Guide to the Human Genome
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Search of human proteins with 84370252

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|84370252 MARVEL domain containing 2 isoform 1 [Homo sapiens]
         (558 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|84370252 MARVEL domain containing 2 isoform 1 [Homo sapiens]      1157   0.0  
gi|21687270 MARVEL domain containing 2 isoform beta [Homo sapiens]    896   0.0  
gi|13375756 occludin/ELL domain containing 1 [Homo sapiens]           119   6e-27
gi|155722987 elongation factor, RNA polymerase II, 2 [Homo sapiens]    91   4e-18
gi|5729812 elongation factor RNA polymerase II [Homo sapiens]          89   1e-17
gi|13376768 elongation factor RNA polymerase II-like 3 [Homo sap...    74   4e-13
gi|4505487 occludin [Homo sapiens]                                     70   5e-12
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa...    42   0.001
gi|38569495 ELL associated factor 1 [Homo sapiens]                     42   0.001
gi|34878904 synaptonemal complex protein 1 [Homo sapiens]              40   0.004
gi|221219020 NYD-SP11 protein [Homo sapiens]                           38   0.028
gi|7705755 plasmolipin [Homo sapiens]                                  38   0.028
gi|5902148 uroplakin 1A [Homo sapiens]                                 37   0.037
gi|65301122 MARVEL domain containing 3 isoform 1 [Homo sapiens]        37   0.037
gi|32130536 CKLF-like MARVEL transmembrane domain containing 8 [...    37   0.048
gi|169207217 PREDICTED: zinc finger homeobox 2 [Homo sapiens]          37   0.062
gi|169207592 PREDICTED: zinc finger homeobox 2 [Homo sapiens]          37   0.062
gi|169207014 PREDICTED: zinc finger homeobox 2 [Homo sapiens]          37   0.062
gi|187761324 shootin1 isoform a [Homo sapiens]                         35   0.14 
gi|18426913 drebrin 1 isoform b [Homo sapiens]                         35   0.24 
gi|18426915 drebrin 1 isoform a [Homo sapiens]                         35   0.24 
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li...    34   0.31 
gi|219555661 intraflagellar transport 81-like isoform 1 [Homo sa...    34   0.31 
gi|34147403 intraflagellar transport 81-like isoform 2 [Homo sap...    34   0.31 
gi|32526901 intraflagellar transport 81-like isoform 1 [Homo sap...    34   0.31 
gi|50083293 coiled-coil domain containing 123 [Homo sapiens]           34   0.31 
gi|4758222 dual-specificity tyrosine-(Y)-phosphorylation regulat...    34   0.40 
gi|5922001 dual-specificity tyrosine-(Y)-phosphorylation regulat...    34   0.40 
gi|5921999 dual-specificity tyrosine-(Y)-phosphorylation regulat...    34   0.40 
gi|18959210 WIRE protein [Homo sapiens]                                34   0.40 

>gi|84370252 MARVEL domain containing 2 isoform 1 [Homo sapiens]
          Length = 558

 Score = 1157 bits (2994), Expect = 0.0
 Identities = 558/558 (100%), Positives = 558/558 (100%)

Query: 1   MSNDGRSRNRDRRYDEVPSDLPYQDTTIRTHPILHDSERAVSADPLPPPPLPLQPPFGPD 60
           MSNDGRSRNRDRRYDEVPSDLPYQDTTIRTHPILHDSERAVSADPLPPPPLPLQPPFGPD
Sbjct: 1   MSNDGRSRNRDRRYDEVPSDLPYQDTTIRTHPILHDSERAVSADPLPPPPLPLQPPFGPD 60

Query: 61  FYSSDTEEPAIAPDLKPVRRFVPDSWKNFFRGKKKDPEWDKPVSDIRYISDGVECSPPAS 120
           FYSSDTEEPAIAPDLKPVRRFVPDSWKNFFRGKKKDPEWDKPVSDIRYISDGVECSPPAS
Sbjct: 61  FYSSDTEEPAIAPDLKPVRRFVPDSWKNFFRGKKKDPEWDKPVSDIRYISDGVECSPPAS 120

Query: 121 PARPNHRSPLNSCKDPYGGSEGTFSSRKEADAVFPRDPYGSLDRHTQTVRTYSEKVEEYN 180
           PARPNHRSPLNSCKDPYGGSEGTFSSRKEADAVFPRDPYGSLDRHTQTVRTYSEKVEEYN
Sbjct: 121 PARPNHRSPLNSCKDPYGGSEGTFSSRKEADAVFPRDPYGSLDRHTQTVRTYSEKVEEYN 180

Query: 181 LRYSYMKSWAGLLRILGVVELLLGAGVFACVTAYIHKDSEWYNLFGYSQPYGMGGVGGLG 240
           LRYSYMKSWAGLLRILGVVELLLGAGVFACVTAYIHKDSEWYNLFGYSQPYGMGGVGGLG
Sbjct: 181 LRYSYMKSWAGLLRILGVVELLLGAGVFACVTAYIHKDSEWYNLFGYSQPYGMGGVGGLG 240

Query: 241 SMYGGYYYTGPKTPFVLVVAGLAWITTIIILVLGMSMYYRTILLDSNWWPLTEFGINVAL 300
           SMYGGYYYTGPKTPFVLVVAGLAWITTIIILVLGMSMYYRTILLDSNWWPLTEFGINVAL
Sbjct: 241 SMYGGYYYTGPKTPFVLVVAGLAWITTIIILVLGMSMYYRTILLDSNWWPLTEFGINVAL 300

Query: 301 FILYMAAAIVYVNDTNRGGLCYYPLFNTPVNAVFCRVEGGQIAAMIFLFVTMIVYLISAL 360
           FILYMAAAIVYVNDTNRGGLCYYPLFNTPVNAVFCRVEGGQIAAMIFLFVTMIVYLISAL
Sbjct: 301 FILYMAAAIVYVNDTNRGGLCYYPLFNTPVNAVFCRVEGGQIAAMIFLFVTMIVYLISAL 360

Query: 361 VCLKLWRHEAARRHREYMEQQEINEPSLSSKRKMCEMATSGDRQRDSEVNFKELRTAKMK 420
           VCLKLWRHEAARRHREYMEQQEINEPSLSSKRKMCEMATSGDRQRDSEVNFKELRTAKMK
Sbjct: 361 VCLKLWRHEAARRHREYMEQQEINEPSLSSKRKMCEMATSGDRQRDSEVNFKELRTAKMK 420

Query: 421 PELLSGHIPPGHIPKPIVMPDYVAKYPVIQTDDERERYKAVFQDQFSEYKELSAEVQAVL 480
           PELLSGHIPPGHIPKPIVMPDYVAKYPVIQTDDERERYKAVFQDQFSEYKELSAEVQAVL
Sbjct: 421 PELLSGHIPPGHIPKPIVMPDYVAKYPVIQTDDERERYKAVFQDQFSEYKELSAEVQAVL 480

Query: 481 RKFDELDAVMSRLPHHSESRQEHERISRIHEEFKKKKNDPTFLEKKERCDYLKNKLSHIK 540
           RKFDELDAVMSRLPHHSESRQEHERISRIHEEFKKKKNDPTFLEKKERCDYLKNKLSHIK
Sbjct: 481 RKFDELDAVMSRLPHHSESRQEHERISRIHEEFKKKKNDPTFLEKKERCDYLKNKLSHIK 540

Query: 541 QRIQEYDKVMNWDVQGYS 558
           QRIQEYDKVMNWDVQGYS
Sbjct: 541 QRIQEYDKVMNWDVQGYS 558


>gi|21687270 MARVEL domain containing 2 isoform beta [Homo sapiens]
          Length = 457

 Score =  896 bits (2316), Expect = 0.0
 Identities = 430/430 (100%), Positives = 430/430 (100%)

Query: 1   MSNDGRSRNRDRRYDEVPSDLPYQDTTIRTHPILHDSERAVSADPLPPPPLPLQPPFGPD 60
           MSNDGRSRNRDRRYDEVPSDLPYQDTTIRTHPILHDSERAVSADPLPPPPLPLQPPFGPD
Sbjct: 1   MSNDGRSRNRDRRYDEVPSDLPYQDTTIRTHPILHDSERAVSADPLPPPPLPLQPPFGPD 60

Query: 61  FYSSDTEEPAIAPDLKPVRRFVPDSWKNFFRGKKKDPEWDKPVSDIRYISDGVECSPPAS 120
           FYSSDTEEPAIAPDLKPVRRFVPDSWKNFFRGKKKDPEWDKPVSDIRYISDGVECSPPAS
Sbjct: 61  FYSSDTEEPAIAPDLKPVRRFVPDSWKNFFRGKKKDPEWDKPVSDIRYISDGVECSPPAS 120

Query: 121 PARPNHRSPLNSCKDPYGGSEGTFSSRKEADAVFPRDPYGSLDRHTQTVRTYSEKVEEYN 180
           PARPNHRSPLNSCKDPYGGSEGTFSSRKEADAVFPRDPYGSLDRHTQTVRTYSEKVEEYN
Sbjct: 121 PARPNHRSPLNSCKDPYGGSEGTFSSRKEADAVFPRDPYGSLDRHTQTVRTYSEKVEEYN 180

Query: 181 LRYSYMKSWAGLLRILGVVELLLGAGVFACVTAYIHKDSEWYNLFGYSQPYGMGGVGGLG 240
           LRYSYMKSWAGLLRILGVVELLLGAGVFACVTAYIHKDSEWYNLFGYSQPYGMGGVGGLG
Sbjct: 181 LRYSYMKSWAGLLRILGVVELLLGAGVFACVTAYIHKDSEWYNLFGYSQPYGMGGVGGLG 240

Query: 241 SMYGGYYYTGPKTPFVLVVAGLAWITTIIILVLGMSMYYRTILLDSNWWPLTEFGINVAL 300
           SMYGGYYYTGPKTPFVLVVAGLAWITTIIILVLGMSMYYRTILLDSNWWPLTEFGINVAL
Sbjct: 241 SMYGGYYYTGPKTPFVLVVAGLAWITTIIILVLGMSMYYRTILLDSNWWPLTEFGINVAL 300

Query: 301 FILYMAAAIVYVNDTNRGGLCYYPLFNTPVNAVFCRVEGGQIAAMIFLFVTMIVYLISAL 360
           FILYMAAAIVYVNDTNRGGLCYYPLFNTPVNAVFCRVEGGQIAAMIFLFVTMIVYLISAL
Sbjct: 301 FILYMAAAIVYVNDTNRGGLCYYPLFNTPVNAVFCRVEGGQIAAMIFLFVTMIVYLISAL 360

Query: 361 VCLKLWRHEAARRHREYMEQQEINEPSLSSKRKMCEMATSGDRQRDSEVNFKELRTAKMK 420
           VCLKLWRHEAARRHREYMEQQEINEPSLSSKRKMCEMATSGDRQRDSEVNFKELRTAKMK
Sbjct: 361 VCLKLWRHEAARRHREYMEQQEINEPSLSSKRKMCEMATSGDRQRDSEVNFKELRTAKMK 420

Query: 421 PELLSGHIPP 430
           PELLSGHIPP
Sbjct: 421 PELLSGHIPP 430


>gi|13375756 occludin/ELL domain containing 1 [Homo sapiens]
          Length = 264

 Score =  119 bits (299), Expect = 6e-27
 Identities = 63/161 (39%), Positives = 98/161 (60%), Gaps = 3/161 (1%)

Query: 389 SSKRKMCEMATSGDRQRDSEVNFKE--LRTAKMKPELLSGHIPPGHIPKPIVMPDYVAKY 446
           S+ R  C+      + +  ++ F++  L  A +  +   G IP GH P+P  +PDY  KY
Sbjct: 94  SAPRPPCQPQPGPHKAKTKKIVFEDELLSQALLGAKKPIGAIPKGHKPRPHPVPDYELKY 153

Query: 447 PVIQTDDERERYKAVFQDQFSEYKELSAEVQAVLRKFDELDAVMSRLPHHSESRQEHERI 506
           P + ++ ER RY AVFQDQ+ E+ EL  EV     K  +L+A++S LP   +S++E +  
Sbjct: 154 PPVSSERERSRYVAVFQDQYGEFLELQHEVGCAQAKLRQLEALLSSLP-PPQSQKEAQVA 212

Query: 507 SRIHEEFKKKKNDPTFLEKKERCDYLKNKLSHIKQRIQEYD 547
           +R+  EF+ K+ DP FL+K+ RC YLK KL H+K +IQ++D
Sbjct: 213 ARVWREFEMKRMDPGFLDKQARCHYLKGKLRHLKTQIQKFD 253


>gi|155722987 elongation factor, RNA polymerase II, 2 [Homo sapiens]
          Length = 640

 Score = 90.5 bits (223), Expect = 4e-18
 Identities = 58/169 (34%), Positives = 90/169 (53%), Gaps = 17/169 (10%)

Query: 381 QEINEPSLSSKRKMCEMATSGDRQRDSEVNFKELRTAKMKPELLSGHIPPGHIPKPIVMP 440
           + I E     KR+  E+A   +   +S    KE  TA M+P  +              +P
Sbjct: 481 ETIEEKEEDLKREE-EIAKLNNSSPNSSGGVKEDCTASMEPSAIE-------------LP 526

Query: 441 DYVAKYPVIQTDDERERYKAVFQDQFSEYKELSAEVQAVLRKFDELDAVMSRL-PHHSES 499
           DY+ KY  I + ++R+ YK  F  ++ EY+ L A ++ V R+F +LDA   RL P   E 
Sbjct: 527 DYLIKYIAIVSYEQRQNYKDDFNAEYDEYRALHARMETVARRFIKLDAQRKRLSPGSKEY 586

Query: 500 RQEHERISRIHEEFKKKKNDPTFLEKKERCDYLKNKLSHIKQRIQEYDK 548
           +  HE +  + E  K K++ P + E+K RC+YL NKL+HIK+ I E+D+
Sbjct: 587 QNVHEEV--LQEYQKIKQSSPNYHEEKYRCEYLHNKLAHIKRLIGEFDQ 633


>gi|5729812 elongation factor RNA polymerase II [Homo sapiens]
          Length = 621

 Score = 89.0 bits (219), Expect = 1e-17
 Identities = 43/111 (38%), Positives = 75/111 (67%), Gaps = 5/111 (4%)

Query: 440 PDYVAKYPVIQTDDERERYKAVFQDQFSEYKELSAEVQAVLRKFDELDAVMSRLPHHSES 499
           PDY+ KY  I + ++R+ YK  F  ++SEY++L A ++ + R+F +LDA + +L   S+ 
Sbjct: 507 PDYLLKYAAISSSEQRQSYKNDFNAEYSEYRDLHARIERITRRFTQLDAQLRQL---SQG 563

Query: 500 RQEHERI-SRIHEEFKK-KKNDPTFLEKKERCDYLKNKLSHIKQRIQEYDK 548
            +E+E    +I +E++K KK +  + ++K RC+YL +KL+HIK+ I EYD+
Sbjct: 564 SEEYETTRGQILQEYRKIKKTNTNYSQEKHRCEYLHSKLAHIKRLIAEYDQ 614


>gi|13376768 elongation factor RNA polymerase II-like 3 [Homo
           sapiens]
          Length = 397

 Score = 73.9 bits (180), Expect = 4e-13
 Identities = 40/116 (34%), Positives = 69/116 (59%), Gaps = 3/116 (2%)

Query: 434 PKPIVMPDYVAKYPVIQTDDERERYKAVFQDQFSEYKELSAEVQAVLRKFDELDAVMSRL 493
           P P  +PDY+ +Y  I + +++  Y+  F+  ++EY+ L A V    ++F EL A + R+
Sbjct: 279 PSPEDIPDYLLQYRAIHSAEQQHAYEQDFETDYAEYRILHARVGTASQRFIELGAEIKRV 338

Query: 494 PHHSESRQEHERISRIHEEFKK-KKNDPTFLEKKERCDYLKNKLSHIKQRIQEYDK 548
              +   +  E   +I +E+KK +K  P++ E+K RC+YL  KLSHIK  I E+++
Sbjct: 339 RRGTPEYKVLE--DKIIQEYKKFRKQYPSYREEKRRCEYLHQKLSHIKGLILEFEE 392


>gi|4505487 occludin [Homo sapiens]
          Length = 522

 Score = 70.1 bits (170), Expect = 5e-12
 Identities = 117/540 (21%), Positives = 203/540 (37%), Gaps = 130/540 (24%)

Query: 113 VECSPPASPA--RPNHRSPLNSCKDPYGGSEGTFSSRKEADAVFPRDPYGSLDRHTQTVR 170
           +E  PP  P   +PNH +P N   D YGG                        R   +  
Sbjct: 6   LESPPPYRPDEFKPNHYAPSN---DIYGGEMHV--------------------RPMLSQP 42

Query: 171 TYSEKVEEYNLRYSYMKSWAGLLRILGVVELLLGAGVFACVTAYIHKDSEW-YNLFGYS- 228
            YS   E+  L +    S  G++RIL ++ +++   +FACV + +  D  +  +L G S 
Sbjct: 43  AYSFYPEDEILHFYKWTSPPGVIRILSMLIIVMCIAIFACVASTLAWDRGYGTSLLGGSV 102

Query: 229 -QPYGMGGVGGLGSMYG-----GYYYTGPKTP-----FVLVVAGLAWITTIIILVLGMSM 277
             PYG  G G  GS YG     GY Y G   P     F+L +A   +I  ++I V  +  
Sbjct: 103 GYPYGGSGFGSYGSGYGYGYGYGYGYGGYTDPRAAKGFMLAMAAFCFIAALVIFVTSV-- 160

Query: 278 YYRTILLDSNWWPLTEFGINVALFILYMAAAIVYVNDTNRGGLCYYPLFNTPVNAV---- 333
             R+ +  +  + L+   ++  L I+   A IVY+   N        L+ + + A+    
Sbjct: 161 -IRSEMSRTRRYYLSVIIVSAILGIMVFIATIVYIMGVNPTAQSSGSLYGSQIYALCNQF 219

Query: 334 ----------------FCRVEGGQIAAMIFLFVTMIVYLISALVCLKLWRH-EAARRHRE 376
                           +C V+  +  A++  F+ ++ + +     +K  R  +   +   
Sbjct: 220 YTPAATGLYVDQYLYHYCVVDPQEAIAIVLGFMIIVAFALIIFFAVKTRRKMDRYDKSNI 279

Query: 377 YMEQQEINEPSLSSKRKMCEMATSGDRQRDSEVNFKELRTAKMKPELLSGHIP-----PG 431
             +++ I +    +  +  +  ++G +   S  +    R         +G +      P 
Sbjct: 280 LWDKEHIYDEQPPNVEEWVKNVSAGTQDVPSPPSDYVERVDSPMAYSSNGKVNDKRFYPE 339

Query: 432 HIPKPIVMPDYVAKYPVIQ-TDDERE-----------------------RYKAVFQDQFS 467
              K   +P+ V + P+    DD R+                       R K   QD + 
Sbjct: 340 SSYKSTPVPEVVQELPLTSPVDDFRQPRYSSGGNFETPSKRAPAKGRAGRSKRTEQDHYE 399

Query: 468 -------------------EYKELSAEVQAVL--RKFD-----------ELDAV---MSR 492
                              EY  ++++ Q  L  R FD           ELD +   +SR
Sbjct: 400 TDYTTGGESCDELEEDWIREYPPITSDQQRQLYKRNFDTGLQEYKSLQSELDEINKELSR 459

Query: 493 LPHH-SESRQEHERISRIHEEF---KKKKNDPTFLEKKERCDYLKNKLSHIKQRIQEYDK 548
           L     + R+E E      +E+   K+ K    +  KK  C  LK+KLSHIK+ + +YD+
Sbjct: 460 LDKELDDYREESEEYMAAADEYNRLKQVKGSADYKSKKNHCKQLKSKLSHIKKMVGDYDR 519


>gi|84043963 eukaryotic translation initiation factor 5B [Homo
           sapiens]
          Length = 1220

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 43/189 (22%), Positives = 84/189 (44%), Gaps = 21/189 (11%)

Query: 369 EAARRHREYMEQQEINEPSLSSKRKMCEMATSGDRQRDSEVNFKELRTAKMKPELLSGHI 428
           E   R R+  ++++     L  K ++        +Q++S+  F+E  T K K  + +G I
Sbjct: 234 EKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEE-ETVKSKVTVDTGVI 292

Query: 429 PPGHIPKPIVMPDYVAKYPVIQTDD------ERERYKAVFQDQFSEYKELSAEVQAVLRK 482
           P           +  A+ P    DD      ++++ K   + +  E ++     +A ++ 
Sbjct: 293 PAS---------EEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKA 343

Query: 483 FDELDAVMSRLPHHSESRQEHERISRIHE-EFKKKKNDPTFLEKKERCDYLKNKLSHIKQ 541
             E  A +       + R+E ERI R+ E E K+K+ +    EK+ER    K K    K+
Sbjct: 344 MQEALAKLKE-EEERQKREEEERIKRLEELEAKRKEEERLEQEKRER---KKQKEKERKE 399

Query: 542 RIQEYDKVM 550
           R+++  K++
Sbjct: 400 RLKKEGKLL 408


>gi|38569495 ELL associated factor 1 [Homo sapiens]
          Length = 268

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 32/101 (31%), Positives = 45/101 (44%), Gaps = 12/101 (11%)

Query: 42  SADPLPPPPLPLQ----PPFGPDFYSSDTEEPAIAPDLKPVRRF------VPDSWKNFFR 91
           S  P PPPP+P +    PP GP   S   + P+  P L  ++R       + +   +   
Sbjct: 134 SQPPPPPPPMPFRAPTKPPVGPKT-SPLKDNPSPEPQLDDIKRELRAEVDIIEQMSSSSG 192

Query: 92  GKKKDPEWDKPVSDIRYISDGVECSPPASPARPNHRSPLNS 132
               D E     SD    S G E + PASP +P+H+ P NS
Sbjct: 193 SSSSDSE-SSSGSDDDSSSSGGEDNGPASPPQPSHQQPYNS 232


>gi|34878904 synaptonemal complex protein 1 [Homo sapiens]
          Length = 976

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 30/159 (18%), Positives = 74/159 (46%), Gaps = 13/159 (8%)

Query: 363 LKLWRHEAARRHREYMEQQEINEPSLSSKRKMCEMATSGDRQRDSEVNFKELRTAKMKPE 422
           +K W+       R+   + + N   + ++RK  +    G+ +    V+ K     +   +
Sbjct: 116 IKKWKVSTEAELRQKESKLQENRKIIEAQRKAIQELQFGNEK----VSLKLEEGIQENKD 171

Query: 423 LLSGHIPPGHIPKPIVMPDYVAKYPVIQTDDERERYKAVFQDQFSEYKELSAEVQAVLRK 482
           L+  +    H+         + K    ++ ++ ++Y+   ++    Y +L+  ++ ++  
Sbjct: 172 LIKENNATRHLCN-------LLKETCARSAEKTKKYEYEREETRQVYMDLNNNIEKMITA 224

Query: 483 FDEL--DAVMSRLPHHSESRQEHERISRIHEEFKKKKND 519
           F+EL   A  SRL  H + ++++E+I  + +E+KK+ ND
Sbjct: 225 FEELRVQAENSRLEMHFKLKEDYEKIQHLEQEYKKEIND 263


>gi|221219020 NYD-SP11 protein [Homo sapiens]
          Length = 2873

 Score = 37.7 bits (86), Expect = 0.028
 Identities = 36/179 (20%), Positives = 80/179 (44%), Gaps = 9/179 (5%)

Query: 379  EQQEINEPSLSSKRKMCEMATSGDRQ--RDSEVNFKELRTAKMKPELLSGHIPPGHIPKP 436
            ++ E+ +      RK  ++A    R   ++ ++  +E + A+   E++      G I + 
Sbjct: 2128 KRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIEEE 2187

Query: 437  IVMPDYVAKYPVIQTDDERERYKAVFQDQFSEYKE---LSAEVQAVLRKFDELDAVMSRL 493
             V+P    ++   +     ++ K  F  Q  E +     S E++++L + ++ +++ S  
Sbjct: 2188 EVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEE 2247

Query: 494  PHHSESRQEHERISRIHEEFKKKKNDPTFLEK---KERCDYLKNKLSHIKQRIQEYDKV 549
                E  +E E    + EE +++K +    EK   KE  +  K K    K+ +QE ++V
Sbjct: 2248 EEEREEEEEREE-EEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEV 2305


>gi|7705755 plasmolipin [Homo sapiens]
          Length = 182

 Score = 37.7 bits (86), Expect = 0.028
 Identities = 30/121 (24%), Positives = 50/121 (41%), Gaps = 14/121 (11%)

Query: 247 YYTGPKTPFVLVVAGLAWITTIIILVLGMSMYYRTILLDSNWWPLTEFGINVALFILYMA 306
           Y+  P   +V+ VA   W+ TI++  L +   +  + +    WPL     N++  +LY+ 
Sbjct: 60  YHLYPAYGWVMFVAVFLWLVTIVLFNLYLFQLHMKLYMVP--WPLVLMIFNISATVLYIT 117

Query: 307 AAIVYVNDTNRGGLCYYPLFNTPVNAVFCRVEGGQIAAMIFLFVTMIVYLISALVCLKLW 366
           A I           C   +  T +     R    + AA  F  + MI Y +SA    + W
Sbjct: 118 AFIA----------CSAAVDLTSLRGT--RPYNQRAAASFFACLVMIAYGVSAFFSYQAW 165

Query: 367 R 367
           R
Sbjct: 166 R 166


>gi|5902148 uroplakin 1A [Homo sapiens]
          Length = 258

 Score = 37.4 bits (85), Expect = 0.037
 Identities = 35/152 (23%), Positives = 71/152 (46%), Gaps = 24/152 (15%)

Query: 258 VVAGLAWITTIIILVLGMSMYYRTILLDSNW---WPLTEFGINVALFILYMAAAIVYVND 314
           VV GL  +  IIIL+ G+S++  TI + ++    +PL   G++    +   A   ++   
Sbjct: 15  VVVGLLVVGNIIILLSGLSLFAETIWVTADQYRVYPL--MGVSGKDDVFAGAWIAIFC-- 70

Query: 315 TNRGGLCYYPLFNTPVNAVFCRVEGGQIAAMIFLFVTMIVYLISALVCLKLWRHEAARRH 374
               G  ++ + +  V A  CR    +   + +L + +IVY+     C+       +  H
Sbjct: 71  ----GFSFFMVASFGVGAALCR---RRSMVLTYLVLMLIVYIFECASCI------TSYTH 117

Query: 375 REYMEQQEINEPSLSSKRKMCEMATSGDRQRD 406
           R+YM    ++ PSL +K+ +   +   D+ ++
Sbjct: 118 RDYM----VSNPSLITKQMLTFYSADTDQGQE 145


>gi|65301122 MARVEL domain containing 3 isoform 1 [Homo sapiens]
          Length = 410

 Score = 37.4 bits (85), Expect = 0.037
 Identities = 48/209 (22%), Positives = 90/209 (43%), Gaps = 37/209 (17%)

Query: 195 ILGVVELLLGAGVFACVTAYIHKDSEWYNLFGYSQPYGMGGVGGLGSMYGGYY------- 247
           ++ +VE++L   V  C+ A       ++ L G+S  +  GG  G G+ Y   +       
Sbjct: 200 VVQIVEVVLNGMVLICIVA------SYFVLAGFSASFSSGG--GFGNNYYSPFEGTELEQ 251

Query: 248 -------YTGPKTPFVLVVAGLAWITTIIILVLGMSMY---YRTILLDSNWWPLTEFGIN 297
                  YT  ++P  L+  G+A    + +L +G+ +     RT+L  S  W LTE   +
Sbjct: 252 VRQLDQQYTILRSP--LIYGGVAVSLGLGVLTMGVLLQGAKSRTML--SGKWLLTEAAFS 307

Query: 298 VALFILYMAAAIVY------VNDTNRGGLCYYPLFNTPVNAVFCRVEGGQIAAMIFLFVT 351
           +   + Y     VY      +N T+             +  + C++ G   AA  F  + 
Sbjct: 308 LLAAVGYCTGIGVYLHVALQINSTDTCKTRERLYARKGLTWMDCQLAGTDGAAATFACLL 367

Query: 352 MIVYLISALVCLKLWRHEAARRHREYMEQ 380
           +I+Y  S ++ L+ +R +  +R++   EQ
Sbjct: 368 VIMYGASVVLALRSYREQ--KRYKGSREQ 394


>gi|32130536 CKLF-like MARVEL transmembrane domain containing 8
           [Homo sapiens]
          Length = 173

 Score = 37.0 bits (84), Expect = 0.048
 Identities = 20/67 (29%), Positives = 34/67 (50%), Gaps = 2/67 (2%)

Query: 244 GGYYYTGPKTPFVLVVAGLAWITTIIILVLGMSMYYRTILLDSNWWPLTEFGINVALFIL 303
           G  Y+  P   +V+ VA   W+ T+  L++ ++M Y  I      W       N + F+L
Sbjct: 61  GTEYFRVPAFGWVMFVAVFYWVLTVFFLIIYITMTYTRI--PQVPWTTVGLCFNGSAFVL 118

Query: 304 YMAAAIV 310
           Y++AA+V
Sbjct: 119 YLSAAVV 125


>gi|169207217 PREDICTED: zinc finger homeobox 2 [Homo sapiens]
          Length = 2790

 Score = 36.6 bits (83), Expect = 0.062
 Identities = 25/74 (33%), Positives = 34/74 (45%), Gaps = 7/74 (9%)

Query: 3    NDGRSRNRDRRYDEVPSDLPYQDTTIRT--HPILHDSERAVSADPLPPPPLPLQPPFGPD 60
            +DG  R   +R  E P+  PY   T+ +   P L   + A +  P P PPLPL PP  P 
Sbjct: 2169 DDGTGREAPKR--EAPA-FPYPTATLASGPQPFLPPGKEATT--PTPEPPLPLLPPPPPS 2223

Query: 61   FYSSDTEEPAIAPD 74
                  E P  +P+
Sbjct: 2224 EEEGPEEPPKASPE 2237


>gi|169207592 PREDICTED: zinc finger homeobox 2 [Homo sapiens]
          Length = 2706

 Score = 36.6 bits (83), Expect = 0.062
 Identities = 25/74 (33%), Positives = 34/74 (45%), Gaps = 7/74 (9%)

Query: 3    NDGRSRNRDRRYDEVPSDLPYQDTTIRT--HPILHDSERAVSADPLPPPPLPLQPPFGPD 60
            +DG  R   +R  E P+  PY   T+ +   P L   + A +  P P PPLPL PP  P 
Sbjct: 2085 DDGTGREAPKR--EAPA-FPYPTATLASGPQPFLPPGKEATT--PTPEPPLPLLPPPPPS 2139

Query: 61   FYSSDTEEPAIAPD 74
                  E P  +P+
Sbjct: 2140 EEEGPEEPPKASPE 2153


>gi|169207014 PREDICTED: zinc finger homeobox 2 [Homo sapiens]
          Length = 2706

 Score = 36.6 bits (83), Expect = 0.062
 Identities = 25/74 (33%), Positives = 34/74 (45%), Gaps = 7/74 (9%)

Query: 3    NDGRSRNRDRRYDEVPSDLPYQDTTIRT--HPILHDSERAVSADPLPPPPLPLQPPFGPD 60
            +DG  R   +R  E P+  PY   T+ +   P L   + A +  P P PPLPL PP  P 
Sbjct: 2085 DDGTGREAPKR--EAPA-FPYPTATLASGPQPFLPPGKEATT--PTPEPPLPLLPPPPPS 2139

Query: 61   FYSSDTEEPAIAPD 74
                  E P  +P+
Sbjct: 2140 EEEGPEEPPKASPE 2153


>gi|187761324 shootin1 isoform a [Homo sapiens]
          Length = 631

 Score = 35.4 bits (80), Expect = 0.14
 Identities = 40/170 (23%), Positives = 60/170 (35%), Gaps = 35/170 (20%)

Query: 15  DEVPSDLPYQDTTIRTHPILHD----------SERAVSADPLPPPPLPLQPPFGPDFYSS 64
           D+   +L YQ++  +   + H           SE +V   P PPPPLP  PP        
Sbjct: 316 DKKELELKYQNSEEKARNLKHSVDELQKRVNQSENSVPPPPPPPPPLPPPPP-------- 367

Query: 65  DTEEPAIAPDLKPVRRFVPDSWKNFFRGKKKDPEWDKPVSDIR---------YISDGVEC 115
                 I   +  +R+    S     + K   PE  + V+D++          I  GV  
Sbjct: 368 ----NPIRSLMSMIRKRSHPSGSGAKKEKATQPETTEEVTDLKRQAVEEMMDRIKKGVHL 423

Query: 116 SPPASPARPNHR----SPLNSCKDPYGGSEGTFSSRKEADAVFPRDPYGS 161
            P    ARP  +        S  D   G  GT +    + ++   DP  S
Sbjct: 424 RPVNQTARPKTKPESSKGCESAVDELKGILGTLNKSTSSRSLKSLDPENS 473


>gi|18426913 drebrin 1 isoform b [Homo sapiens]
          Length = 651

 Score = 34.7 bits (78), Expect = 0.24
 Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 17/76 (22%)

Query: 17  VPSDLPYQDTTIRTHPILHDSERAVSA------DPLPPPPLPLQPPFGPDFYSSDTEEPA 70
           +P+  P   +T  T P+    ERA+         PLPPPP P Q          +T+EP+
Sbjct: 335 IPTRSPSDSSTAST-PVAEQIERALDEVTSSQPPPLPPPPPPAQ----------ETQEPS 383

Query: 71  IAPDLKPVRRFVPDSW 86
              D +  R   P +W
Sbjct: 384 PILDSEETRAAAPQAW 399


>gi|18426915 drebrin 1 isoform a [Homo sapiens]
          Length = 649

 Score = 34.7 bits (78), Expect = 0.24
 Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 17/76 (22%)

Query: 17  VPSDLPYQDTTIRTHPILHDSERAVSA------DPLPPPPLPLQPPFGPDFYSSDTEEPA 70
           +P+  P   +T  T P+    ERA+         PLPPPP P Q          +T+EP+
Sbjct: 333 IPTRSPSDSSTAST-PVAEQIERALDEVTSSQPPPLPPPPPPAQ----------ETQEPS 381

Query: 71  IAPDLKPVRRFVPDSW 86
              D +  R   P +W
Sbjct: 382 PILDSEETRAAAPQAW 397


>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 828

 Score = 34.3 bits (77), Expect = 0.31
 Identities = 38/193 (19%), Positives = 79/193 (40%), Gaps = 10/193 (5%)

Query: 364 KLWRHEAARRHREYMEQQEINEPSLSSKRKMCE----MATSGDRQRDSEVNFKELRTAKM 419
           K+WR E  R   + M +QE  E     ++KM +    M    +R R+ E   +E +    
Sbjct: 474 KMWRQEKMREQEDQMWEQE--EKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQ 531

Query: 420 KPELLSGHIPPGHIPKPIVMPDYVAKYPVIQTDDERERYKAVFQDQFSEYKELSAEVQAV 479
           + E +          K     D   K    +   ERE+     ++   E +E   E +  
Sbjct: 532 QEEKMREEKKTQEQEKKTW--DQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEK 589

Query: 480 LRKFDELDAVMSRLPHHSESR--QEHERISRIHEEFKKKKNDPTFLEKKERCDYLKNKLS 537
           +R+ +E            E +  ++ E++    EE K ++ +    E++E+    + K+ 
Sbjct: 590 MREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMW 649

Query: 538 HIKQRIQEYDKVM 550
             +++++E ++ M
Sbjct: 650 EQEEKMREQEEKM 662


>gi|219555661 intraflagellar transport 81-like isoform 1 [Homo
           sapiens]
          Length = 676

 Score = 34.3 bits (77), Expect = 0.31
 Identities = 27/117 (23%), Positives = 57/117 (48%), Gaps = 12/117 (10%)

Query: 438 VMPDYVAKYPVIQTDDERERYKAVFQDQFSEYKEL------SAEVQAVLRKFDE-LDAVM 490
           V  +++    V  T+ + E     F+    EY++L      +AE++  +   +E  D ++
Sbjct: 127 VPSEFLQDETVADTNKQYEELMEAFKTLHKEYEQLKISGFSTAEIRKDISAMEEEKDQLI 186

Query: 491 SRLPH---HSESRQEHERISRIHEEFKKKKNDPTFLEKKERCDYLKNKLSHIKQRIQ 544
            R+ H     E+ Q H+ + +I  + + +K    +L ++++    KN+L H  QR+Q
Sbjct: 187 KRVEHLKKRVETAQNHQWMLKIARQLRVEKEREEYLAQQKQ--EQKNQLFHAVQRLQ 241


>gi|34147403 intraflagellar transport 81-like isoform 2 [Homo
           sapiens]
          Length = 431

 Score = 34.3 bits (77), Expect = 0.31
 Identities = 27/117 (23%), Positives = 57/117 (48%), Gaps = 12/117 (10%)

Query: 438 VMPDYVAKYPVIQTDDERERYKAVFQDQFSEYKEL------SAEVQAVLRKFDE-LDAVM 490
           V  +++    V  T+ + E     F+    EY++L      +AE++  +   +E  D ++
Sbjct: 127 VPSEFLQDETVADTNKQYEELMEAFKTLHKEYEQLKISGFSTAEIRKDISAMEEEKDQLI 186

Query: 491 SRLPH---HSESRQEHERISRIHEEFKKKKNDPTFLEKKERCDYLKNKLSHIKQRIQ 544
            R+ H     E+ Q H+ + +I  + + +K    +L ++++    KN+L H  QR+Q
Sbjct: 187 KRVEHLKKRVETAQNHQWMLKIARQLRVEKEREEYLAQQKQ--EQKNQLFHAVQRLQ 241


>gi|32526901 intraflagellar transport 81-like isoform 1 [Homo
           sapiens]
          Length = 676

 Score = 34.3 bits (77), Expect = 0.31
 Identities = 27/117 (23%), Positives = 57/117 (48%), Gaps = 12/117 (10%)

Query: 438 VMPDYVAKYPVIQTDDERERYKAVFQDQFSEYKEL------SAEVQAVLRKFDE-LDAVM 490
           V  +++    V  T+ + E     F+    EY++L      +AE++  +   +E  D ++
Sbjct: 127 VPSEFLQDETVADTNKQYEELMEAFKTLHKEYEQLKISGFSTAEIRKDISAMEEEKDQLI 186

Query: 491 SRLPH---HSESRQEHERISRIHEEFKKKKNDPTFLEKKERCDYLKNKLSHIKQRIQ 544
            R+ H     E+ Q H+ + +I  + + +K    +L ++++    KN+L H  QR+Q
Sbjct: 187 KRVEHLKKRVETAQNHQWMLKIARQLRVEKEREEYLAQQKQ--EQKNQLFHAVQRLQ 241


>gi|50083293 coiled-coil domain containing 123 [Homo sapiens]
          Length = 783

 Score = 34.3 bits (77), Expect = 0.31
 Identities = 40/188 (21%), Positives = 78/188 (41%), Gaps = 3/188 (1%)

Query: 363 LKLWRHEAARRHREYMEQQEINEPSLSSKRKMCEMATSGDRQRDSEVNFKELRTAKMKPE 422
           L L + E  +R  +   Q+ + E S  +K+ M   A +  ++++   N ++L   + K +
Sbjct: 439 LLLEQLEIQQRKAKDSHQERLQEVSKLTKQLMLLEAKTHGQEKELAENREQLEILRAKCQ 498

Query: 423 LLSGHIPPGHIPKPIVMPDYVAKYPVIQTDDERERYKAVFQDQFSEYKELSAEVQAVLRK 482
            L  H   G I   + +   +      Q   E E+ +A  ++   +   L A+ +++L +
Sbjct: 499 ELKTH-SDGKIA--VEVHKSIVNELKSQLQKEEEKERAEMEELMEKLTVLQAQKKSLLLE 555

Query: 483 FDELDAVMSRLPHHSESRQEHERISRIHEEFKKKKNDPTFLEKKERCDYLKNKLSHIKQR 542
            + L      L    E  Q+  R S+   E  KK+ +     +     YL N +   +  
Sbjct: 556 KNSLTEQNKALEAELERAQKINRKSQKKIEVLKKQVEKAMGNEMSAHQYLANLVGLAENI 615

Query: 543 IQEYDKVM 550
            QE D +M
Sbjct: 616 TQERDSLM 623


>gi|4758222 dual-specificity tyrosine-(Y)-phosphorylation regulated
           kinase 1B isoform a [Homo sapiens]
          Length = 629

 Score = 33.9 bits (76), Expect = 0.40
 Identities = 23/84 (27%), Positives = 33/84 (39%), Gaps = 4/84 (4%)

Query: 45  PLPPPPLPLQPPFGPDFYSSDTEEPAIAPDLKPVRRFVPDSWKNFFRGKKKDPEWDKP-- 102
           P  PP  PL+P  G D      + PA A  L      +P   +  + G+   P    P  
Sbjct: 505 PQVPPSQPLRPWAGGDVPHKTHQAPASASSLPGTGAQLPPQPR--YLGRPPSPTSPPPPE 562

Query: 103 VSDIRYISDGVECSPPASPARPNH 126
           + D+  +    +CSPP     P H
Sbjct: 563 LMDVSLVGGPADCSPPHPAPAPQH 586


>gi|5922001 dual-specificity tyrosine-(Y)-phosphorylation regulated
           kinase 1B isoform c [Homo sapiens]
          Length = 601

 Score = 33.9 bits (76), Expect = 0.40
 Identities = 23/84 (27%), Positives = 33/84 (39%), Gaps = 4/84 (4%)

Query: 45  PLPPPPLPLQPPFGPDFYSSDTEEPAIAPDLKPVRRFVPDSWKNFFRGKKKDPEWDKP-- 102
           P  PP  PL+P  G D      + PA A  L      +P   +  + G+   P    P  
Sbjct: 477 PQVPPSQPLRPWAGGDVPHKTHQAPASASSLPGTGAQLPPQPR--YLGRPPSPTSPPPPE 534

Query: 103 VSDIRYISDGVECSPPASPARPNH 126
           + D+  +    +CSPP     P H
Sbjct: 535 LMDVSLVGGPADCSPPHPAPAPQH 558


>gi|5921999 dual-specificity tyrosine-(Y)-phosphorylation regulated
           kinase 1B isoform b [Homo sapiens]
          Length = 589

 Score = 33.9 bits (76), Expect = 0.40
 Identities = 23/84 (27%), Positives = 33/84 (39%), Gaps = 4/84 (4%)

Query: 45  PLPPPPLPLQPPFGPDFYSSDTEEPAIAPDLKPVRRFVPDSWKNFFRGKKKDPEWDKP-- 102
           P  PP  PL+P  G D      + PA A  L      +P   +  + G+   P    P  
Sbjct: 465 PQVPPSQPLRPWAGGDVPHKTHQAPASASSLPGTGAQLPPQPR--YLGRPPSPTSPPPPE 522

Query: 103 VSDIRYISDGVECSPPASPARPNH 126
           + D+  +    +CSPP     P H
Sbjct: 523 LMDVSLVGGPADCSPPHPAPAPQH 546


>gi|18959210 WIRE protein [Homo sapiens]
          Length = 440

 Score = 33.9 bits (76), Expect = 0.40
 Identities = 13/28 (46%), Positives = 19/28 (67%)

Query: 47 PPPPLPLQPPFGPDFYSSDTEEPAIAPD 74
          PPPP P  PP  P F+ ++TE+P ++ D
Sbjct: 5  PPPPPPPGPPPPPTFHQANTEQPKLSRD 32



 Score = 30.0 bits (66), Expect = 5.8
 Identities = 40/161 (24%), Positives = 57/161 (35%), Gaps = 30/161 (18%)

Query: 47  PPPPLPLQPPFGPDFYSSDTEEPAIAPDLK------------PVRRFVP----DSWKNFF 90
           PPPP   QPP  P+  SS T E   AP+L             PVR   P     +  +  
Sbjct: 250 PPPPPYRQPPGVPNGPSSPTNES--APELPQRHNSLHRKTPGPVRGLAPPPPTSASPSLL 307

Query: 91  RGKKKDPEWDKPVSDIR------YISDGVECSPPASPARPNHRSPLNSCKDPYGGSEGTF 144
             +   P  D P            I +G   +PP  P    H S     + P  G     
Sbjct: 308 SNRPPPPARDPPSRGAAPPPPPPVIRNGARDAPPPPPPYRMHGS-----EPPSRGKPPPP 362

Query: 145 SSRKEADAVFPRDPYGSLDRHTQTVRTYSEKVEEYNLRYSY 185
            SR  A    P  P    + H  ++ T    ++++  +YS+
Sbjct: 363 PSRTPAGPP-PPPPPPLRNGHRDSITTVRSFLDDFESKYSF 402


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.137    0.425 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,112,998
Number of Sequences: 37866
Number of extensions: 1238542
Number of successful extensions: 8029
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 33
Number of HSP's successfully gapped in prelim test: 144
Number of HSP's that attempted gapping in prelim test: 7622
Number of HSP's gapped (non-prelim): 470
length of query: 558
length of database: 18,247,518
effective HSP length: 107
effective length of query: 451
effective length of database: 14,195,856
effective search space: 6402331056
effective search space used: 6402331056
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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