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Search of human proteins with 84370252
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|84370252 MARVEL domain containing 2 isoform 1 [Homo sapiens]
(558 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|84370252 MARVEL domain containing 2 isoform 1 [Homo sapiens] 1157 0.0
gi|21687270 MARVEL domain containing 2 isoform beta [Homo sapiens] 896 0.0
gi|13375756 occludin/ELL domain containing 1 [Homo sapiens] 119 6e-27
gi|155722987 elongation factor, RNA polymerase II, 2 [Homo sapiens] 91 4e-18
gi|5729812 elongation factor RNA polymerase II [Homo sapiens] 89 1e-17
gi|13376768 elongation factor RNA polymerase II-like 3 [Homo sap... 74 4e-13
gi|4505487 occludin [Homo sapiens] 70 5e-12
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 42 0.001
gi|38569495 ELL associated factor 1 [Homo sapiens] 42 0.001
gi|34878904 synaptonemal complex protein 1 [Homo sapiens] 40 0.004
gi|221219020 NYD-SP11 protein [Homo sapiens] 38 0.028
gi|7705755 plasmolipin [Homo sapiens] 38 0.028
gi|5902148 uroplakin 1A [Homo sapiens] 37 0.037
gi|65301122 MARVEL domain containing 3 isoform 1 [Homo sapiens] 37 0.037
gi|32130536 CKLF-like MARVEL transmembrane domain containing 8 [... 37 0.048
gi|169207217 PREDICTED: zinc finger homeobox 2 [Homo sapiens] 37 0.062
gi|169207592 PREDICTED: zinc finger homeobox 2 [Homo sapiens] 37 0.062
gi|169207014 PREDICTED: zinc finger homeobox 2 [Homo sapiens] 37 0.062
gi|187761324 shootin1 isoform a [Homo sapiens] 35 0.14
gi|18426913 drebrin 1 isoform b [Homo sapiens] 35 0.24
gi|18426915 drebrin 1 isoform a [Homo sapiens] 35 0.24
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 34 0.31
gi|219555661 intraflagellar transport 81-like isoform 1 [Homo sa... 34 0.31
gi|34147403 intraflagellar transport 81-like isoform 2 [Homo sap... 34 0.31
gi|32526901 intraflagellar transport 81-like isoform 1 [Homo sap... 34 0.31
gi|50083293 coiled-coil domain containing 123 [Homo sapiens] 34 0.31
gi|4758222 dual-specificity tyrosine-(Y)-phosphorylation regulat... 34 0.40
gi|5922001 dual-specificity tyrosine-(Y)-phosphorylation regulat... 34 0.40
gi|5921999 dual-specificity tyrosine-(Y)-phosphorylation regulat... 34 0.40
gi|18959210 WIRE protein [Homo sapiens] 34 0.40
>gi|84370252 MARVEL domain containing 2 isoform 1 [Homo sapiens]
Length = 558
Score = 1157 bits (2994), Expect = 0.0
Identities = 558/558 (100%), Positives = 558/558 (100%)
Query: 1 MSNDGRSRNRDRRYDEVPSDLPYQDTTIRTHPILHDSERAVSADPLPPPPLPLQPPFGPD 60
MSNDGRSRNRDRRYDEVPSDLPYQDTTIRTHPILHDSERAVSADPLPPPPLPLQPPFGPD
Sbjct: 1 MSNDGRSRNRDRRYDEVPSDLPYQDTTIRTHPILHDSERAVSADPLPPPPLPLQPPFGPD 60
Query: 61 FYSSDTEEPAIAPDLKPVRRFVPDSWKNFFRGKKKDPEWDKPVSDIRYISDGVECSPPAS 120
FYSSDTEEPAIAPDLKPVRRFVPDSWKNFFRGKKKDPEWDKPVSDIRYISDGVECSPPAS
Sbjct: 61 FYSSDTEEPAIAPDLKPVRRFVPDSWKNFFRGKKKDPEWDKPVSDIRYISDGVECSPPAS 120
Query: 121 PARPNHRSPLNSCKDPYGGSEGTFSSRKEADAVFPRDPYGSLDRHTQTVRTYSEKVEEYN 180
PARPNHRSPLNSCKDPYGGSEGTFSSRKEADAVFPRDPYGSLDRHTQTVRTYSEKVEEYN
Sbjct: 121 PARPNHRSPLNSCKDPYGGSEGTFSSRKEADAVFPRDPYGSLDRHTQTVRTYSEKVEEYN 180
Query: 181 LRYSYMKSWAGLLRILGVVELLLGAGVFACVTAYIHKDSEWYNLFGYSQPYGMGGVGGLG 240
LRYSYMKSWAGLLRILGVVELLLGAGVFACVTAYIHKDSEWYNLFGYSQPYGMGGVGGLG
Sbjct: 181 LRYSYMKSWAGLLRILGVVELLLGAGVFACVTAYIHKDSEWYNLFGYSQPYGMGGVGGLG 240
Query: 241 SMYGGYYYTGPKTPFVLVVAGLAWITTIIILVLGMSMYYRTILLDSNWWPLTEFGINVAL 300
SMYGGYYYTGPKTPFVLVVAGLAWITTIIILVLGMSMYYRTILLDSNWWPLTEFGINVAL
Sbjct: 241 SMYGGYYYTGPKTPFVLVVAGLAWITTIIILVLGMSMYYRTILLDSNWWPLTEFGINVAL 300
Query: 301 FILYMAAAIVYVNDTNRGGLCYYPLFNTPVNAVFCRVEGGQIAAMIFLFVTMIVYLISAL 360
FILYMAAAIVYVNDTNRGGLCYYPLFNTPVNAVFCRVEGGQIAAMIFLFVTMIVYLISAL
Sbjct: 301 FILYMAAAIVYVNDTNRGGLCYYPLFNTPVNAVFCRVEGGQIAAMIFLFVTMIVYLISAL 360
Query: 361 VCLKLWRHEAARRHREYMEQQEINEPSLSSKRKMCEMATSGDRQRDSEVNFKELRTAKMK 420
VCLKLWRHEAARRHREYMEQQEINEPSLSSKRKMCEMATSGDRQRDSEVNFKELRTAKMK
Sbjct: 361 VCLKLWRHEAARRHREYMEQQEINEPSLSSKRKMCEMATSGDRQRDSEVNFKELRTAKMK 420
Query: 421 PELLSGHIPPGHIPKPIVMPDYVAKYPVIQTDDERERYKAVFQDQFSEYKELSAEVQAVL 480
PELLSGHIPPGHIPKPIVMPDYVAKYPVIQTDDERERYKAVFQDQFSEYKELSAEVQAVL
Sbjct: 421 PELLSGHIPPGHIPKPIVMPDYVAKYPVIQTDDERERYKAVFQDQFSEYKELSAEVQAVL 480
Query: 481 RKFDELDAVMSRLPHHSESRQEHERISRIHEEFKKKKNDPTFLEKKERCDYLKNKLSHIK 540
RKFDELDAVMSRLPHHSESRQEHERISRIHEEFKKKKNDPTFLEKKERCDYLKNKLSHIK
Sbjct: 481 RKFDELDAVMSRLPHHSESRQEHERISRIHEEFKKKKNDPTFLEKKERCDYLKNKLSHIK 540
Query: 541 QRIQEYDKVMNWDVQGYS 558
QRIQEYDKVMNWDVQGYS
Sbjct: 541 QRIQEYDKVMNWDVQGYS 558
>gi|21687270 MARVEL domain containing 2 isoform beta [Homo sapiens]
Length = 457
Score = 896 bits (2316), Expect = 0.0
Identities = 430/430 (100%), Positives = 430/430 (100%)
Query: 1 MSNDGRSRNRDRRYDEVPSDLPYQDTTIRTHPILHDSERAVSADPLPPPPLPLQPPFGPD 60
MSNDGRSRNRDRRYDEVPSDLPYQDTTIRTHPILHDSERAVSADPLPPPPLPLQPPFGPD
Sbjct: 1 MSNDGRSRNRDRRYDEVPSDLPYQDTTIRTHPILHDSERAVSADPLPPPPLPLQPPFGPD 60
Query: 61 FYSSDTEEPAIAPDLKPVRRFVPDSWKNFFRGKKKDPEWDKPVSDIRYISDGVECSPPAS 120
FYSSDTEEPAIAPDLKPVRRFVPDSWKNFFRGKKKDPEWDKPVSDIRYISDGVECSPPAS
Sbjct: 61 FYSSDTEEPAIAPDLKPVRRFVPDSWKNFFRGKKKDPEWDKPVSDIRYISDGVECSPPAS 120
Query: 121 PARPNHRSPLNSCKDPYGGSEGTFSSRKEADAVFPRDPYGSLDRHTQTVRTYSEKVEEYN 180
PARPNHRSPLNSCKDPYGGSEGTFSSRKEADAVFPRDPYGSLDRHTQTVRTYSEKVEEYN
Sbjct: 121 PARPNHRSPLNSCKDPYGGSEGTFSSRKEADAVFPRDPYGSLDRHTQTVRTYSEKVEEYN 180
Query: 181 LRYSYMKSWAGLLRILGVVELLLGAGVFACVTAYIHKDSEWYNLFGYSQPYGMGGVGGLG 240
LRYSYMKSWAGLLRILGVVELLLGAGVFACVTAYIHKDSEWYNLFGYSQPYGMGGVGGLG
Sbjct: 181 LRYSYMKSWAGLLRILGVVELLLGAGVFACVTAYIHKDSEWYNLFGYSQPYGMGGVGGLG 240
Query: 241 SMYGGYYYTGPKTPFVLVVAGLAWITTIIILVLGMSMYYRTILLDSNWWPLTEFGINVAL 300
SMYGGYYYTGPKTPFVLVVAGLAWITTIIILVLGMSMYYRTILLDSNWWPLTEFGINVAL
Sbjct: 241 SMYGGYYYTGPKTPFVLVVAGLAWITTIIILVLGMSMYYRTILLDSNWWPLTEFGINVAL 300
Query: 301 FILYMAAAIVYVNDTNRGGLCYYPLFNTPVNAVFCRVEGGQIAAMIFLFVTMIVYLISAL 360
FILYMAAAIVYVNDTNRGGLCYYPLFNTPVNAVFCRVEGGQIAAMIFLFVTMIVYLISAL
Sbjct: 301 FILYMAAAIVYVNDTNRGGLCYYPLFNTPVNAVFCRVEGGQIAAMIFLFVTMIVYLISAL 360
Query: 361 VCLKLWRHEAARRHREYMEQQEINEPSLSSKRKMCEMATSGDRQRDSEVNFKELRTAKMK 420
VCLKLWRHEAARRHREYMEQQEINEPSLSSKRKMCEMATSGDRQRDSEVNFKELRTAKMK
Sbjct: 361 VCLKLWRHEAARRHREYMEQQEINEPSLSSKRKMCEMATSGDRQRDSEVNFKELRTAKMK 420
Query: 421 PELLSGHIPP 430
PELLSGHIPP
Sbjct: 421 PELLSGHIPP 430
>gi|13375756 occludin/ELL domain containing 1 [Homo sapiens]
Length = 264
Score = 119 bits (299), Expect = 6e-27
Identities = 63/161 (39%), Positives = 98/161 (60%), Gaps = 3/161 (1%)
Query: 389 SSKRKMCEMATSGDRQRDSEVNFKE--LRTAKMKPELLSGHIPPGHIPKPIVMPDYVAKY 446
S+ R C+ + + ++ F++ L A + + G IP GH P+P +PDY KY
Sbjct: 94 SAPRPPCQPQPGPHKAKTKKIVFEDELLSQALLGAKKPIGAIPKGHKPRPHPVPDYELKY 153
Query: 447 PVIQTDDERERYKAVFQDQFSEYKELSAEVQAVLRKFDELDAVMSRLPHHSESRQEHERI 506
P + ++ ER RY AVFQDQ+ E+ EL EV K +L+A++S LP +S++E +
Sbjct: 154 PPVSSERERSRYVAVFQDQYGEFLELQHEVGCAQAKLRQLEALLSSLP-PPQSQKEAQVA 212
Query: 507 SRIHEEFKKKKNDPTFLEKKERCDYLKNKLSHIKQRIQEYD 547
+R+ EF+ K+ DP FL+K+ RC YLK KL H+K +IQ++D
Sbjct: 213 ARVWREFEMKRMDPGFLDKQARCHYLKGKLRHLKTQIQKFD 253
>gi|155722987 elongation factor, RNA polymerase II, 2 [Homo sapiens]
Length = 640
Score = 90.5 bits (223), Expect = 4e-18
Identities = 58/169 (34%), Positives = 90/169 (53%), Gaps = 17/169 (10%)
Query: 381 QEINEPSLSSKRKMCEMATSGDRQRDSEVNFKELRTAKMKPELLSGHIPPGHIPKPIVMP 440
+ I E KR+ E+A + +S KE TA M+P + +P
Sbjct: 481 ETIEEKEEDLKREE-EIAKLNNSSPNSSGGVKEDCTASMEPSAIE-------------LP 526
Query: 441 DYVAKYPVIQTDDERERYKAVFQDQFSEYKELSAEVQAVLRKFDELDAVMSRL-PHHSES 499
DY+ KY I + ++R+ YK F ++ EY+ L A ++ V R+F +LDA RL P E
Sbjct: 527 DYLIKYIAIVSYEQRQNYKDDFNAEYDEYRALHARMETVARRFIKLDAQRKRLSPGSKEY 586
Query: 500 RQEHERISRIHEEFKKKKNDPTFLEKKERCDYLKNKLSHIKQRIQEYDK 548
+ HE + + E K K++ P + E+K RC+YL NKL+HIK+ I E+D+
Sbjct: 587 QNVHEEV--LQEYQKIKQSSPNYHEEKYRCEYLHNKLAHIKRLIGEFDQ 633
>gi|5729812 elongation factor RNA polymerase II [Homo sapiens]
Length = 621
Score = 89.0 bits (219), Expect = 1e-17
Identities = 43/111 (38%), Positives = 75/111 (67%), Gaps = 5/111 (4%)
Query: 440 PDYVAKYPVIQTDDERERYKAVFQDQFSEYKELSAEVQAVLRKFDELDAVMSRLPHHSES 499
PDY+ KY I + ++R+ YK F ++SEY++L A ++ + R+F +LDA + +L S+
Sbjct: 507 PDYLLKYAAISSSEQRQSYKNDFNAEYSEYRDLHARIERITRRFTQLDAQLRQL---SQG 563
Query: 500 RQEHERI-SRIHEEFKK-KKNDPTFLEKKERCDYLKNKLSHIKQRIQEYDK 548
+E+E +I +E++K KK + + ++K RC+YL +KL+HIK+ I EYD+
Sbjct: 564 SEEYETTRGQILQEYRKIKKTNTNYSQEKHRCEYLHSKLAHIKRLIAEYDQ 614
>gi|13376768 elongation factor RNA polymerase II-like 3 [Homo
sapiens]
Length = 397
Score = 73.9 bits (180), Expect = 4e-13
Identities = 40/116 (34%), Positives = 69/116 (59%), Gaps = 3/116 (2%)
Query: 434 PKPIVMPDYVAKYPVIQTDDERERYKAVFQDQFSEYKELSAEVQAVLRKFDELDAVMSRL 493
P P +PDY+ +Y I + +++ Y+ F+ ++EY+ L A V ++F EL A + R+
Sbjct: 279 PSPEDIPDYLLQYRAIHSAEQQHAYEQDFETDYAEYRILHARVGTASQRFIELGAEIKRV 338
Query: 494 PHHSESRQEHERISRIHEEFKK-KKNDPTFLEKKERCDYLKNKLSHIKQRIQEYDK 548
+ + E +I +E+KK +K P++ E+K RC+YL KLSHIK I E+++
Sbjct: 339 RRGTPEYKVLE--DKIIQEYKKFRKQYPSYREEKRRCEYLHQKLSHIKGLILEFEE 392
>gi|4505487 occludin [Homo sapiens]
Length = 522
Score = 70.1 bits (170), Expect = 5e-12
Identities = 117/540 (21%), Positives = 203/540 (37%), Gaps = 130/540 (24%)
Query: 113 VECSPPASPA--RPNHRSPLNSCKDPYGGSEGTFSSRKEADAVFPRDPYGSLDRHTQTVR 170
+E PP P +PNH +P N D YGG R +
Sbjct: 6 LESPPPYRPDEFKPNHYAPSN---DIYGGEMHV--------------------RPMLSQP 42
Query: 171 TYSEKVEEYNLRYSYMKSWAGLLRILGVVELLLGAGVFACVTAYIHKDSEW-YNLFGYS- 228
YS E+ L + S G++RIL ++ +++ +FACV + + D + +L G S
Sbjct: 43 AYSFYPEDEILHFYKWTSPPGVIRILSMLIIVMCIAIFACVASTLAWDRGYGTSLLGGSV 102
Query: 229 -QPYGMGGVGGLGSMYG-----GYYYTGPKTP-----FVLVVAGLAWITTIIILVLGMSM 277
PYG G G GS YG GY Y G P F+L +A +I ++I V +
Sbjct: 103 GYPYGGSGFGSYGSGYGYGYGYGYGYGGYTDPRAAKGFMLAMAAFCFIAALVIFVTSV-- 160
Query: 278 YYRTILLDSNWWPLTEFGINVALFILYMAAAIVYVNDTNRGGLCYYPLFNTPVNAV---- 333
R+ + + + L+ ++ L I+ A IVY+ N L+ + + A+
Sbjct: 161 -IRSEMSRTRRYYLSVIIVSAILGIMVFIATIVYIMGVNPTAQSSGSLYGSQIYALCNQF 219
Query: 334 ----------------FCRVEGGQIAAMIFLFVTMIVYLISALVCLKLWRH-EAARRHRE 376
+C V+ + A++ F+ ++ + + +K R + +
Sbjct: 220 YTPAATGLYVDQYLYHYCVVDPQEAIAIVLGFMIIVAFALIIFFAVKTRRKMDRYDKSNI 279
Query: 377 YMEQQEINEPSLSSKRKMCEMATSGDRQRDSEVNFKELRTAKMKPELLSGHIP-----PG 431
+++ I + + + + ++G + S + R +G + P
Sbjct: 280 LWDKEHIYDEQPPNVEEWVKNVSAGTQDVPSPPSDYVERVDSPMAYSSNGKVNDKRFYPE 339
Query: 432 HIPKPIVMPDYVAKYPVIQ-TDDERE-----------------------RYKAVFQDQFS 467
K +P+ V + P+ DD R+ R K QD +
Sbjct: 340 SSYKSTPVPEVVQELPLTSPVDDFRQPRYSSGGNFETPSKRAPAKGRAGRSKRTEQDHYE 399
Query: 468 -------------------EYKELSAEVQAVL--RKFD-----------ELDAV---MSR 492
EY ++++ Q L R FD ELD + +SR
Sbjct: 400 TDYTTGGESCDELEEDWIREYPPITSDQQRQLYKRNFDTGLQEYKSLQSELDEINKELSR 459
Query: 493 LPHH-SESRQEHERISRIHEEF---KKKKNDPTFLEKKERCDYLKNKLSHIKQRIQEYDK 548
L + R+E E +E+ K+ K + KK C LK+KLSHIK+ + +YD+
Sbjct: 460 LDKELDDYREESEEYMAAADEYNRLKQVKGSADYKSKKNHCKQLKSKLSHIKKMVGDYDR 519
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 42.4 bits (98), Expect = 0.001
Identities = 43/189 (22%), Positives = 84/189 (44%), Gaps = 21/189 (11%)
Query: 369 EAARRHREYMEQQEINEPSLSSKRKMCEMATSGDRQRDSEVNFKELRTAKMKPELLSGHI 428
E R R+ ++++ L K ++ +Q++S+ F+E T K K + +G I
Sbjct: 234 EKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEE-ETVKSKVTVDTGVI 292
Query: 429 PPGHIPKPIVMPDYVAKYPVIQTDD------ERERYKAVFQDQFSEYKELSAEVQAVLRK 482
P + A+ P DD ++++ K + + E ++ +A ++
Sbjct: 293 PAS---------EEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKA 343
Query: 483 FDELDAVMSRLPHHSESRQEHERISRIHE-EFKKKKNDPTFLEKKERCDYLKNKLSHIKQ 541
E A + + R+E ERI R+ E E K+K+ + EK+ER K K K+
Sbjct: 344 MQEALAKLKE-EEERQKREEEERIKRLEELEAKRKEEERLEQEKRER---KKQKEKERKE 399
Query: 542 RIQEYDKVM 550
R+++ K++
Sbjct: 400 RLKKEGKLL 408
>gi|38569495 ELL associated factor 1 [Homo sapiens]
Length = 268
Score = 42.0 bits (97), Expect = 0.001
Identities = 32/101 (31%), Positives = 45/101 (44%), Gaps = 12/101 (11%)
Query: 42 SADPLPPPPLPLQ----PPFGPDFYSSDTEEPAIAPDLKPVRRF------VPDSWKNFFR 91
S P PPPP+P + PP GP S + P+ P L ++R + + +
Sbjct: 134 SQPPPPPPPMPFRAPTKPPVGPKT-SPLKDNPSPEPQLDDIKRELRAEVDIIEQMSSSSG 192
Query: 92 GKKKDPEWDKPVSDIRYISDGVECSPPASPARPNHRSPLNS 132
D E SD S G E + PASP +P+H+ P NS
Sbjct: 193 SSSSDSE-SSSGSDDDSSSSGGEDNGPASPPQPSHQQPYNS 232
>gi|34878904 synaptonemal complex protein 1 [Homo sapiens]
Length = 976
Score = 40.4 bits (93), Expect = 0.004
Identities = 30/159 (18%), Positives = 74/159 (46%), Gaps = 13/159 (8%)
Query: 363 LKLWRHEAARRHREYMEQQEINEPSLSSKRKMCEMATSGDRQRDSEVNFKELRTAKMKPE 422
+K W+ R+ + + N + ++RK + G+ + V+ K + +
Sbjct: 116 IKKWKVSTEAELRQKESKLQENRKIIEAQRKAIQELQFGNEK----VSLKLEEGIQENKD 171
Query: 423 LLSGHIPPGHIPKPIVMPDYVAKYPVIQTDDERERYKAVFQDQFSEYKELSAEVQAVLRK 482
L+ + H+ + K ++ ++ ++Y+ ++ Y +L+ ++ ++
Sbjct: 172 LIKENNATRHLCN-------LLKETCARSAEKTKKYEYEREETRQVYMDLNNNIEKMITA 224
Query: 483 FDEL--DAVMSRLPHHSESRQEHERISRIHEEFKKKKND 519
F+EL A SRL H + ++++E+I + +E+KK+ ND
Sbjct: 225 FEELRVQAENSRLEMHFKLKEDYEKIQHLEQEYKKEIND 263
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 37.7 bits (86), Expect = 0.028
Identities = 36/179 (20%), Positives = 80/179 (44%), Gaps = 9/179 (5%)
Query: 379 EQQEINEPSLSSKRKMCEMATSGDRQ--RDSEVNFKELRTAKMKPELLSGHIPPGHIPKP 436
++ E+ + RK ++A R ++ ++ +E + A+ E++ G I +
Sbjct: 2128 KRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIEEE 2187
Query: 437 IVMPDYVAKYPVIQTDDERERYKAVFQDQFSEYKE---LSAEVQAVLRKFDELDAVMSRL 493
V+P ++ + ++ K F Q E + S E++++L + ++ +++ S
Sbjct: 2188 EVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEE 2247
Query: 494 PHHSESRQEHERISRIHEEFKKKKNDPTFLEK---KERCDYLKNKLSHIKQRIQEYDKV 549
E +E E + EE +++K + EK KE + K K K+ +QE ++V
Sbjct: 2248 EEEREEEEEREE-EEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEV 2305
>gi|7705755 plasmolipin [Homo sapiens]
Length = 182
Score = 37.7 bits (86), Expect = 0.028
Identities = 30/121 (24%), Positives = 50/121 (41%), Gaps = 14/121 (11%)
Query: 247 YYTGPKTPFVLVVAGLAWITTIIILVLGMSMYYRTILLDSNWWPLTEFGINVALFILYMA 306
Y+ P +V+ VA W+ TI++ L + + + + WPL N++ +LY+
Sbjct: 60 YHLYPAYGWVMFVAVFLWLVTIVLFNLYLFQLHMKLYMVP--WPLVLMIFNISATVLYIT 117
Query: 307 AAIVYVNDTNRGGLCYYPLFNTPVNAVFCRVEGGQIAAMIFLFVTMIVYLISALVCLKLW 366
A I C + T + R + AA F + MI Y +SA + W
Sbjct: 118 AFIA----------CSAAVDLTSLRGT--RPYNQRAAASFFACLVMIAYGVSAFFSYQAW 165
Query: 367 R 367
R
Sbjct: 166 R 166
>gi|5902148 uroplakin 1A [Homo sapiens]
Length = 258
Score = 37.4 bits (85), Expect = 0.037
Identities = 35/152 (23%), Positives = 71/152 (46%), Gaps = 24/152 (15%)
Query: 258 VVAGLAWITTIIILVLGMSMYYRTILLDSNW---WPLTEFGINVALFILYMAAAIVYVND 314
VV GL + IIIL+ G+S++ TI + ++ +PL G++ + A ++
Sbjct: 15 VVVGLLVVGNIIILLSGLSLFAETIWVTADQYRVYPL--MGVSGKDDVFAGAWIAIFC-- 70
Query: 315 TNRGGLCYYPLFNTPVNAVFCRVEGGQIAAMIFLFVTMIVYLISALVCLKLWRHEAARRH 374
G ++ + + V A CR + + +L + +IVY+ C+ + H
Sbjct: 71 ----GFSFFMVASFGVGAALCR---RRSMVLTYLVLMLIVYIFECASCI------TSYTH 117
Query: 375 REYMEQQEINEPSLSSKRKMCEMATSGDRQRD 406
R+YM ++ PSL +K+ + + D+ ++
Sbjct: 118 RDYM----VSNPSLITKQMLTFYSADTDQGQE 145
>gi|65301122 MARVEL domain containing 3 isoform 1 [Homo sapiens]
Length = 410
Score = 37.4 bits (85), Expect = 0.037
Identities = 48/209 (22%), Positives = 90/209 (43%), Gaps = 37/209 (17%)
Query: 195 ILGVVELLLGAGVFACVTAYIHKDSEWYNLFGYSQPYGMGGVGGLGSMYGGYY------- 247
++ +VE++L V C+ A ++ L G+S + GG G G+ Y +
Sbjct: 200 VVQIVEVVLNGMVLICIVA------SYFVLAGFSASFSSGG--GFGNNYYSPFEGTELEQ 251
Query: 248 -------YTGPKTPFVLVVAGLAWITTIIILVLGMSMY---YRTILLDSNWWPLTEFGIN 297
YT ++P L+ G+A + +L +G+ + RT+L S W LTE +
Sbjct: 252 VRQLDQQYTILRSP--LIYGGVAVSLGLGVLTMGVLLQGAKSRTML--SGKWLLTEAAFS 307
Query: 298 VALFILYMAAAIVY------VNDTNRGGLCYYPLFNTPVNAVFCRVEGGQIAAMIFLFVT 351
+ + Y VY +N T+ + + C++ G AA F +
Sbjct: 308 LLAAVGYCTGIGVYLHVALQINSTDTCKTRERLYARKGLTWMDCQLAGTDGAAATFACLL 367
Query: 352 MIVYLISALVCLKLWRHEAARRHREYMEQ 380
+I+Y S ++ L+ +R + +R++ EQ
Sbjct: 368 VIMYGASVVLALRSYREQ--KRYKGSREQ 394
>gi|32130536 CKLF-like MARVEL transmembrane domain containing 8
[Homo sapiens]
Length = 173
Score = 37.0 bits (84), Expect = 0.048
Identities = 20/67 (29%), Positives = 34/67 (50%), Gaps = 2/67 (2%)
Query: 244 GGYYYTGPKTPFVLVVAGLAWITTIIILVLGMSMYYRTILLDSNWWPLTEFGINVALFIL 303
G Y+ P +V+ VA W+ T+ L++ ++M Y I W N + F+L
Sbjct: 61 GTEYFRVPAFGWVMFVAVFYWVLTVFFLIIYITMTYTRI--PQVPWTTVGLCFNGSAFVL 118
Query: 304 YMAAAIV 310
Y++AA+V
Sbjct: 119 YLSAAVV 125
>gi|169207217 PREDICTED: zinc finger homeobox 2 [Homo sapiens]
Length = 2790
Score = 36.6 bits (83), Expect = 0.062
Identities = 25/74 (33%), Positives = 34/74 (45%), Gaps = 7/74 (9%)
Query: 3 NDGRSRNRDRRYDEVPSDLPYQDTTIRT--HPILHDSERAVSADPLPPPPLPLQPPFGPD 60
+DG R +R E P+ PY T+ + P L + A + P P PPLPL PP P
Sbjct: 2169 DDGTGREAPKR--EAPA-FPYPTATLASGPQPFLPPGKEATT--PTPEPPLPLLPPPPPS 2223
Query: 61 FYSSDTEEPAIAPD 74
E P +P+
Sbjct: 2224 EEEGPEEPPKASPE 2237
>gi|169207592 PREDICTED: zinc finger homeobox 2 [Homo sapiens]
Length = 2706
Score = 36.6 bits (83), Expect = 0.062
Identities = 25/74 (33%), Positives = 34/74 (45%), Gaps = 7/74 (9%)
Query: 3 NDGRSRNRDRRYDEVPSDLPYQDTTIRT--HPILHDSERAVSADPLPPPPLPLQPPFGPD 60
+DG R +R E P+ PY T+ + P L + A + P P PPLPL PP P
Sbjct: 2085 DDGTGREAPKR--EAPA-FPYPTATLASGPQPFLPPGKEATT--PTPEPPLPLLPPPPPS 2139
Query: 61 FYSSDTEEPAIAPD 74
E P +P+
Sbjct: 2140 EEEGPEEPPKASPE 2153
>gi|169207014 PREDICTED: zinc finger homeobox 2 [Homo sapiens]
Length = 2706
Score = 36.6 bits (83), Expect = 0.062
Identities = 25/74 (33%), Positives = 34/74 (45%), Gaps = 7/74 (9%)
Query: 3 NDGRSRNRDRRYDEVPSDLPYQDTTIRT--HPILHDSERAVSADPLPPPPLPLQPPFGPD 60
+DG R +R E P+ PY T+ + P L + A + P P PPLPL PP P
Sbjct: 2085 DDGTGREAPKR--EAPA-FPYPTATLASGPQPFLPPGKEATT--PTPEPPLPLLPPPPPS 2139
Query: 61 FYSSDTEEPAIAPD 74
E P +P+
Sbjct: 2140 EEEGPEEPPKASPE 2153
>gi|187761324 shootin1 isoform a [Homo sapiens]
Length = 631
Score = 35.4 bits (80), Expect = 0.14
Identities = 40/170 (23%), Positives = 60/170 (35%), Gaps = 35/170 (20%)
Query: 15 DEVPSDLPYQDTTIRTHPILHD----------SERAVSADPLPPPPLPLQPPFGPDFYSS 64
D+ +L YQ++ + + H SE +V P PPPPLP PP
Sbjct: 316 DKKELELKYQNSEEKARNLKHSVDELQKRVNQSENSVPPPPPPPPPLPPPPP-------- 367
Query: 65 DTEEPAIAPDLKPVRRFVPDSWKNFFRGKKKDPEWDKPVSDIR---------YISDGVEC 115
I + +R+ S + K PE + V+D++ I GV
Sbjct: 368 ----NPIRSLMSMIRKRSHPSGSGAKKEKATQPETTEEVTDLKRQAVEEMMDRIKKGVHL 423
Query: 116 SPPASPARPNHR----SPLNSCKDPYGGSEGTFSSRKEADAVFPRDPYGS 161
P ARP + S D G GT + + ++ DP S
Sbjct: 424 RPVNQTARPKTKPESSKGCESAVDELKGILGTLNKSTSSRSLKSLDPENS 473
>gi|18426913 drebrin 1 isoform b [Homo sapiens]
Length = 651
Score = 34.7 bits (78), Expect = 0.24
Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 17/76 (22%)
Query: 17 VPSDLPYQDTTIRTHPILHDSERAVSA------DPLPPPPLPLQPPFGPDFYSSDTEEPA 70
+P+ P +T T P+ ERA+ PLPPPP P Q +T+EP+
Sbjct: 335 IPTRSPSDSSTAST-PVAEQIERALDEVTSSQPPPLPPPPPPAQ----------ETQEPS 383
Query: 71 IAPDLKPVRRFVPDSW 86
D + R P +W
Sbjct: 384 PILDSEETRAAAPQAW 399
>gi|18426915 drebrin 1 isoform a [Homo sapiens]
Length = 649
Score = 34.7 bits (78), Expect = 0.24
Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 17/76 (22%)
Query: 17 VPSDLPYQDTTIRTHPILHDSERAVSA------DPLPPPPLPLQPPFGPDFYSSDTEEPA 70
+P+ P +T T P+ ERA+ PLPPPP P Q +T+EP+
Sbjct: 333 IPTRSPSDSSTAST-PVAEQIERALDEVTSSQPPPLPPPPPPAQ----------ETQEPS 381
Query: 71 IAPDLKPVRRFVPDSW 86
D + R P +W
Sbjct: 382 PILDSEETRAAAPQAW 397
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 34.3 bits (77), Expect = 0.31
Identities = 38/193 (19%), Positives = 79/193 (40%), Gaps = 10/193 (5%)
Query: 364 KLWRHEAARRHREYMEQQEINEPSLSSKRKMCE----MATSGDRQRDSEVNFKELRTAKM 419
K+WR E R + M +QE E ++KM + M +R R+ E +E +
Sbjct: 474 KMWRQEKMREQEDQMWEQE--EKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQ 531
Query: 420 KPELLSGHIPPGHIPKPIVMPDYVAKYPVIQTDDERERYKAVFQDQFSEYKELSAEVQAV 479
+ E + K D K + ERE+ ++ E +E E +
Sbjct: 532 QEEKMREEKKTQEQEKKTW--DQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEK 589
Query: 480 LRKFDELDAVMSRLPHHSESR--QEHERISRIHEEFKKKKNDPTFLEKKERCDYLKNKLS 537
+R+ +E E + ++ E++ EE K ++ + E++E+ + K+
Sbjct: 590 MREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMW 649
Query: 538 HIKQRIQEYDKVM 550
+++++E ++ M
Sbjct: 650 EQEEKMREQEEKM 662
>gi|219555661 intraflagellar transport 81-like isoform 1 [Homo
sapiens]
Length = 676
Score = 34.3 bits (77), Expect = 0.31
Identities = 27/117 (23%), Positives = 57/117 (48%), Gaps = 12/117 (10%)
Query: 438 VMPDYVAKYPVIQTDDERERYKAVFQDQFSEYKEL------SAEVQAVLRKFDE-LDAVM 490
V +++ V T+ + E F+ EY++L +AE++ + +E D ++
Sbjct: 127 VPSEFLQDETVADTNKQYEELMEAFKTLHKEYEQLKISGFSTAEIRKDISAMEEEKDQLI 186
Query: 491 SRLPH---HSESRQEHERISRIHEEFKKKKNDPTFLEKKERCDYLKNKLSHIKQRIQ 544
R+ H E+ Q H+ + +I + + +K +L ++++ KN+L H QR+Q
Sbjct: 187 KRVEHLKKRVETAQNHQWMLKIARQLRVEKEREEYLAQQKQ--EQKNQLFHAVQRLQ 241
>gi|34147403 intraflagellar transport 81-like isoform 2 [Homo
sapiens]
Length = 431
Score = 34.3 bits (77), Expect = 0.31
Identities = 27/117 (23%), Positives = 57/117 (48%), Gaps = 12/117 (10%)
Query: 438 VMPDYVAKYPVIQTDDERERYKAVFQDQFSEYKEL------SAEVQAVLRKFDE-LDAVM 490
V +++ V T+ + E F+ EY++L +AE++ + +E D ++
Sbjct: 127 VPSEFLQDETVADTNKQYEELMEAFKTLHKEYEQLKISGFSTAEIRKDISAMEEEKDQLI 186
Query: 491 SRLPH---HSESRQEHERISRIHEEFKKKKNDPTFLEKKERCDYLKNKLSHIKQRIQ 544
R+ H E+ Q H+ + +I + + +K +L ++++ KN+L H QR+Q
Sbjct: 187 KRVEHLKKRVETAQNHQWMLKIARQLRVEKEREEYLAQQKQ--EQKNQLFHAVQRLQ 241
>gi|32526901 intraflagellar transport 81-like isoform 1 [Homo
sapiens]
Length = 676
Score = 34.3 bits (77), Expect = 0.31
Identities = 27/117 (23%), Positives = 57/117 (48%), Gaps = 12/117 (10%)
Query: 438 VMPDYVAKYPVIQTDDERERYKAVFQDQFSEYKEL------SAEVQAVLRKFDE-LDAVM 490
V +++ V T+ + E F+ EY++L +AE++ + +E D ++
Sbjct: 127 VPSEFLQDETVADTNKQYEELMEAFKTLHKEYEQLKISGFSTAEIRKDISAMEEEKDQLI 186
Query: 491 SRLPH---HSESRQEHERISRIHEEFKKKKNDPTFLEKKERCDYLKNKLSHIKQRIQ 544
R+ H E+ Q H+ + +I + + +K +L ++++ KN+L H QR+Q
Sbjct: 187 KRVEHLKKRVETAQNHQWMLKIARQLRVEKEREEYLAQQKQ--EQKNQLFHAVQRLQ 241
>gi|50083293 coiled-coil domain containing 123 [Homo sapiens]
Length = 783
Score = 34.3 bits (77), Expect = 0.31
Identities = 40/188 (21%), Positives = 78/188 (41%), Gaps = 3/188 (1%)
Query: 363 LKLWRHEAARRHREYMEQQEINEPSLSSKRKMCEMATSGDRQRDSEVNFKELRTAKMKPE 422
L L + E +R + Q+ + E S +K+ M A + ++++ N ++L + K +
Sbjct: 439 LLLEQLEIQQRKAKDSHQERLQEVSKLTKQLMLLEAKTHGQEKELAENREQLEILRAKCQ 498
Query: 423 LLSGHIPPGHIPKPIVMPDYVAKYPVIQTDDERERYKAVFQDQFSEYKELSAEVQAVLRK 482
L H G I + + + Q E E+ +A ++ + L A+ +++L +
Sbjct: 499 ELKTH-SDGKIA--VEVHKSIVNELKSQLQKEEEKERAEMEELMEKLTVLQAQKKSLLLE 555
Query: 483 FDELDAVMSRLPHHSESRQEHERISRIHEEFKKKKNDPTFLEKKERCDYLKNKLSHIKQR 542
+ L L E Q+ R S+ E KK+ + + YL N + +
Sbjct: 556 KNSLTEQNKALEAELERAQKINRKSQKKIEVLKKQVEKAMGNEMSAHQYLANLVGLAENI 615
Query: 543 IQEYDKVM 550
QE D +M
Sbjct: 616 TQERDSLM 623
>gi|4758222 dual-specificity tyrosine-(Y)-phosphorylation regulated
kinase 1B isoform a [Homo sapiens]
Length = 629
Score = 33.9 bits (76), Expect = 0.40
Identities = 23/84 (27%), Positives = 33/84 (39%), Gaps = 4/84 (4%)
Query: 45 PLPPPPLPLQPPFGPDFYSSDTEEPAIAPDLKPVRRFVPDSWKNFFRGKKKDPEWDKP-- 102
P PP PL+P G D + PA A L +P + + G+ P P
Sbjct: 505 PQVPPSQPLRPWAGGDVPHKTHQAPASASSLPGTGAQLPPQPR--YLGRPPSPTSPPPPE 562
Query: 103 VSDIRYISDGVECSPPASPARPNH 126
+ D+ + +CSPP P H
Sbjct: 563 LMDVSLVGGPADCSPPHPAPAPQH 586
>gi|5922001 dual-specificity tyrosine-(Y)-phosphorylation regulated
kinase 1B isoform c [Homo sapiens]
Length = 601
Score = 33.9 bits (76), Expect = 0.40
Identities = 23/84 (27%), Positives = 33/84 (39%), Gaps = 4/84 (4%)
Query: 45 PLPPPPLPLQPPFGPDFYSSDTEEPAIAPDLKPVRRFVPDSWKNFFRGKKKDPEWDKP-- 102
P PP PL+P G D + PA A L +P + + G+ P P
Sbjct: 477 PQVPPSQPLRPWAGGDVPHKTHQAPASASSLPGTGAQLPPQPR--YLGRPPSPTSPPPPE 534
Query: 103 VSDIRYISDGVECSPPASPARPNH 126
+ D+ + +CSPP P H
Sbjct: 535 LMDVSLVGGPADCSPPHPAPAPQH 558
>gi|5921999 dual-specificity tyrosine-(Y)-phosphorylation regulated
kinase 1B isoform b [Homo sapiens]
Length = 589
Score = 33.9 bits (76), Expect = 0.40
Identities = 23/84 (27%), Positives = 33/84 (39%), Gaps = 4/84 (4%)
Query: 45 PLPPPPLPLQPPFGPDFYSSDTEEPAIAPDLKPVRRFVPDSWKNFFRGKKKDPEWDKP-- 102
P PP PL+P G D + PA A L +P + + G+ P P
Sbjct: 465 PQVPPSQPLRPWAGGDVPHKTHQAPASASSLPGTGAQLPPQPR--YLGRPPSPTSPPPPE 522
Query: 103 VSDIRYISDGVECSPPASPARPNH 126
+ D+ + +CSPP P H
Sbjct: 523 LMDVSLVGGPADCSPPHPAPAPQH 546
>gi|18959210 WIRE protein [Homo sapiens]
Length = 440
Score = 33.9 bits (76), Expect = 0.40
Identities = 13/28 (46%), Positives = 19/28 (67%)
Query: 47 PPPPLPLQPPFGPDFYSSDTEEPAIAPD 74
PPPP P PP P F+ ++TE+P ++ D
Sbjct: 5 PPPPPPPGPPPPPTFHQANTEQPKLSRD 32
Score = 30.0 bits (66), Expect = 5.8
Identities = 40/161 (24%), Positives = 57/161 (35%), Gaps = 30/161 (18%)
Query: 47 PPPPLPLQPPFGPDFYSSDTEEPAIAPDLK------------PVRRFVP----DSWKNFF 90
PPPP QPP P+ SS T E AP+L PVR P + +
Sbjct: 250 PPPPPYRQPPGVPNGPSSPTNES--APELPQRHNSLHRKTPGPVRGLAPPPPTSASPSLL 307
Query: 91 RGKKKDPEWDKPVSDIR------YISDGVECSPPASPARPNHRSPLNSCKDPYGGSEGTF 144
+ P D P I +G +PP P H S + P G
Sbjct: 308 SNRPPPPARDPPSRGAAPPPPPPVIRNGARDAPPPPPPYRMHGS-----EPPSRGKPPPP 362
Query: 145 SSRKEADAVFPRDPYGSLDRHTQTVRTYSEKVEEYNLRYSY 185
SR A P P + H ++ T ++++ +YS+
Sbjct: 363 PSRTPAGPP-PPPPPPLRNGHRDSITTVRSFLDDFESKYSF 402
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.137 0.425
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,112,998
Number of Sequences: 37866
Number of extensions: 1238542
Number of successful extensions: 8029
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 33
Number of HSP's successfully gapped in prelim test: 144
Number of HSP's that attempted gapping in prelim test: 7622
Number of HSP's gapped (non-prelim): 470
length of query: 558
length of database: 18,247,518
effective HSP length: 107
effective length of query: 451
effective length of database: 14,195,856
effective search space: 6402331056
effective search space used: 6402331056
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.