Guide to the Human Genome
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Search of human proteins with 83779010

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|83779010 SECIS binding protein 2 [Homo sapiens]
         (854 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|83779010 SECIS binding protein 2 [Homo sapiens]                   1705   0.0  
gi|60685227 SECIS binding protein 2-like [Homo sapiens]               313   4e-85
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1...    48   3e-05
gi|193788653 hypothetical protein LOC100131897 [Homo sapiens]          45   4e-04
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     44   6e-04
gi|153945728 microtubule-associated protein 1B [Homo sapiens]          42   0.002
gi|110349788 absent, small, or homeotic 1-like [Homo sapiens]          42   0.002
gi|197927454 DEK oncogene isoform 2 [Homo sapiens]                     42   0.003
gi|56676335 RAP1 interacting factor 1 [Homo sapiens]                   42   0.003
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa...    41   0.004
gi|239753245 PREDICTED: similar to UPF0634 protein C [Homo sapiens]    41   0.005
gi|117553580 adaptor-related protein complex 3, delta 1 subunit ...    40   0.007
gi|83367077 mucin 16 [Homo sapiens]                                    40   0.007
gi|34335264 zinc finger, MYND-type containing 8 isoform c [Homo ...    40   0.009
gi|34335262 zinc finger, MYND-type containing 8 isoform a [Homo ...    40   0.009
gi|34335266 zinc finger, MYND-type containing 8 isoform b [Homo ...    40   0.009
gi|226817313 SH3 and multiple ankyrin repeat domains 2 isoform 1...    40   0.012
gi|4503249 DEK oncogene isoform 1 [Homo sapiens]                       39   0.016
gi|27734775 hypothetical protein LOC286499 [Homo sapiens]              39   0.016
gi|148746195 trichohyalin [Homo sapiens]                               39   0.020
gi|102467242 inner centromere protein antigens 135/155kDa isofor...    39   0.020
gi|154090979 hypothetical protein LOC57481 [Homo sapiens]              39   0.027
gi|134304846 Rb1-inducible coiled coil protein 1 isoform 2 [Homo...    38   0.035
gi|134304842 Rb1-inducible coiled coil protein 1 isoform 1 [Homo...    38   0.035
gi|219842214 protein phosphatase 1, regulatory (inhibitor) subun...    38   0.046
gi|219842212 protein phosphatase 1, regulatory (inhibitor) subun...    38   0.046
gi|4505317 protein phosphatase 1, regulatory (inhibitor) subunit...    38   0.046
gi|40068059 CBF1 interacting corepressor [Homo sapiens]                37   0.060
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]    37   0.078
gi|4758876 poly(A) binding protein, nuclear 1 [Homo sapiens]           37   0.10 

>gi|83779010 SECIS binding protein 2 [Homo sapiens]
          Length = 854

 Score = 1705 bits (4416), Expect = 0.0
 Identities = 854/854 (100%), Positives = 854/854 (100%)

Query: 1   MASEGPREPESEGIKLSADVKPFVPRFAGLNVAWLESSEACVFPSSAATYYPFVQEPPVT 60
           MASEGPREPESEGIKLSADVKPFVPRFAGLNVAWLESSEACVFPSSAATYYPFVQEPPVT
Sbjct: 1   MASEGPREPESEGIKLSADVKPFVPRFAGLNVAWLESSEACVFPSSAATYYPFVQEPPVT 60

Query: 61  EQKIYTEDMAFGASTFPPQYLSSEITLHPYAYSPYTLDSTQNVYSVPGSQYLYNQPSCYR 120
           EQKIYTEDMAFGASTFPPQYLSSEITLHPYAYSPYTLDSTQNVYSVPGSQYLYNQPSCYR
Sbjct: 61  EQKIYTEDMAFGASTFPPQYLSSEITLHPYAYSPYTLDSTQNVYSVPGSQYLYNQPSCYR 120

Query: 121 GFQTVKHRNENTCPLPQEMKALFKKKTYDEKKTYDQQKFDSERADGTISSEIKSARGSHH 180
           GFQTVKHRNENTCPLPQEMKALFKKKTYDEKKTYDQQKFDSERADGTISSEIKSARGSHH
Sbjct: 121 GFQTVKHRNENTCPLPQEMKALFKKKTYDEKKTYDQQKFDSERADGTISSEIKSARGSHH 180

Query: 181 LSIYAENSLKSDGYHKRTDRKSRIIAKNVSTSKPEFEFTTLDFPELQGAENNMSEIQKQP 240
           LSIYAENSLKSDGYHKRTDRKSRIIAKNVSTSKPEFEFTTLDFPELQGAENNMSEIQKQP
Sbjct: 181 LSIYAENSLKSDGYHKRTDRKSRIIAKNVSTSKPEFEFTTLDFPELQGAENNMSEIQKQP 240

Query: 241 KWGPVHSVSTDISLLREVVKPAAVLSKGEIVVKNNPNESVTANAATNSPSCTRELSWTPM 300
           KWGPVHSVSTDISLLREVVKPAAVLSKGEIVVKNNPNESVTANAATNSPSCTRELSWTPM
Sbjct: 241 KWGPVHSVSTDISLLREVVKPAAVLSKGEIVVKNNPNESVTANAATNSPSCTRELSWTPM 300

Query: 301 GYVVRQTLSTELSAAPKNVTSMINLKTIASSADPKNVSIPSSEALSSDPSYNKEKHIIHP 360
           GYVVRQTLSTELSAAPKNVTSMINLKTIASSADPKNVSIPSSEALSSDPSYNKEKHIIHP
Sbjct: 301 GYVVRQTLSTELSAAPKNVTSMINLKTIASSADPKNVSIPSSEALSSDPSYNKEKHIIHP 360

Query: 361 TQKSKASQGSDLEQNEASRKNKKKKEKSTSKYEVLTVQEPPRIEDAEEFPNLAVASERRD 420
           TQKSKASQGSDLEQNEASRKNKKKKEKSTSKYEVLTVQEPPRIEDAEEFPNLAVASERRD
Sbjct: 361 TQKSKASQGSDLEQNEASRKNKKKKEKSTSKYEVLTVQEPPRIEDAEEFPNLAVASERRD 420

Query: 421 RIETPKFQSKQQPQDNFKNNVKKSQLPVQLDLGGMLTALEKKQHSQHAKQSSKPVVVSVG 480
           RIETPKFQSKQQPQDNFKNNVKKSQLPVQLDLGGMLTALEKKQHSQHAKQSSKPVVVSVG
Sbjct: 421 RIETPKFQSKQQPQDNFKNNVKKSQLPVQLDLGGMLTALEKKQHSQHAKQSSKPVVVSVG 480

Query: 481 AVPVLSKECASGERGRRMSQMKTPHNPLDSSAPLMKKGKQREIPKAKKPTSLKKIILKER 540
           AVPVLSKECASGERGRRMSQMKTPHNPLDSSAPLMKKGKQREIPKAKKPTSLKKIILKER
Sbjct: 481 AVPVLSKECASGERGRRMSQMKTPHNPLDSSAPLMKKGKQREIPKAKKPTSLKKIILKER 540

Query: 541 QERKQRLQENAVSPAFTSDDTQDGESGGDDQFPEQAELSGPEGMDELISTPSVEDKSEEP 600
           QERKQRLQENAVSPAFTSDDTQDGESGGDDQFPEQAELSGPEGMDELISTPSVEDKSEEP
Sbjct: 541 QERKQRLQENAVSPAFTSDDTQDGESGGDDQFPEQAELSGPEGMDELISTPSVEDKSEEP 600

Query: 601 PGTELQRDTEASHLAPNHTTFPKIHSRRFRDYCSQMLSKEVDACVTDLLKELVRFQDRMY 660
           PGTELQRDTEASHLAPNHTTFPKIHSRRFRDYCSQMLSKEVDACVTDLLKELVRFQDRMY
Sbjct: 601 PGTELQRDTEASHLAPNHTTFPKIHSRRFRDYCSQMLSKEVDACVTDLLKELVRFQDRMY 660

Query: 661 QKDPVKAKTKRRLVLGLREVLKHLKLKKLKCVIISPNCEKIQSKGGLDDTLHTIIDYACE 720
           QKDPVKAKTKRRLVLGLREVLKHLKLKKLKCVIISPNCEKIQSKGGLDDTLHTIIDYACE
Sbjct: 661 QKDPVKAKTKRRLVLGLREVLKHLKLKKLKCVIISPNCEKIQSKGGLDDTLHTIIDYACE 720

Query: 721 QNIPFVFALNRKALGRSLNKAVPVSVVGIFSYDGAQDQFHKMVELTVAARQAYKTMLENV 780
           QNIPFVFALNRKALGRSLNKAVPVSVVGIFSYDGAQDQFHKMVELTVAARQAYKTMLENV
Sbjct: 721 QNIPFVFALNRKALGRSLNKAVPVSVVGIFSYDGAQDQFHKMVELTVAARQAYKTMLENV 780

Query: 781 QQELVGEPRPQAPPSLPTQGPSCPAEDGPPALKEKEEPHYIEIWKKHLEAYSGCTLELEE 840
           QQELVGEPRPQAPPSLPTQGPSCPAEDGPPALKEKEEPHYIEIWKKHLEAYSGCTLELEE
Sbjct: 781 QQELVGEPRPQAPPSLPTQGPSCPAEDGPPALKEKEEPHYIEIWKKHLEAYSGCTLELEE 840

Query: 841 SLEASTSQMMNLNL 854
           SLEASTSQMMNLNL
Sbjct: 841 SLEASTSQMMNLNL 854


>gi|60685227 SECIS binding protein 2-like [Homo sapiens]
          Length = 1056

 Score =  313 bits (802), Expect = 4e-85
 Identities = 267/899 (29%), Positives = 410/899 (45%), Gaps = 98/899 (10%)

Query: 7   REPESEGIKLSADVKPFVPRFAGLNVAWLESS-----------EACVFPSSAATYYPFVQ 55
           R P  + +KLSA+V+PF+P+    +   +  +           E    PS   T YPFVQ
Sbjct: 3   RAPTEQNVKLSAEVEPFIPQKKSPDTFMIPMALPNDNGSVSGVEPTPIPSYLITCYPFVQ 62

Query: 56  EPPVTEQ-KIYTEDMAF---GASTFPPQYLSSEITLHPYAYSPYTLDSTQNVYSVPGSQY 111
           E     Q  +Y  D+ +     +   P +    I+  P   + YT      +   P +Q 
Sbjct: 63  ENQSNRQFPLYNNDIRWQQPNPNPTGPYFAYPIISAQPPVSTEYTY---YQLMPAPCAQV 119

Query: 112 LYNQPSCYRGFQTVKHRNENTCPLPQEMKALFKKKTYDEKKTYDQQKFDSERADGTISSE 171
           +      Y  F T      NT      + A+  + T    +        S R+       
Sbjct: 120 M----GFYHPFPTPY---SNTFQAANTVNAITTECTERPSQLGQVFPLSSHRS------- 165

Query: 172 IKSARGSHHLSIYAENSLKSDGYHKRTDRKSRIIAKNVSTSKPEFEFTTLDFPELQGAEN 231
               R S+  S+  +  L          +  R + KNV+T K     T    P+ +    
Sbjct: 166 ----RNSNRGSVVPKQQLLQQHI-----KSKRPLVKNVATQKE----TNAAGPDSRSKIV 212

Query: 232 NMSEIQKQPKWGPVHSVSTDIS--LLREVVKPAAVLSKGEIVVKNNPNESVTANAATNSP 289
            + +  +Q  +       +DI+   L E        SKG     ++P    ++    +  
Sbjct: 213 LLVDASQQTDF------PSDIANKSLSETTATMLWKSKGRRRRASHPTAESSSEQGASEA 266

Query: 290 SCTRELSWTPMGYVVRQTLSTELSAAPKNVTSMINLKTIASSADPKNVSIPSSEA---LS 346
               +  +    +   Q  +  L        + +     A   +  NV+  +++    + 
Sbjct: 267 DIDSDSGYCSPKHSNNQPAAGALRNPDSGTMNHVESSMCAGGVNWSNVTCQATQKKPWME 326

Query: 347 SDPSYNKEKHIIHPTQKSKASQGSDLEQNEASRKNKKKKEKSTSKY--------EVLTVQ 398
            + ++++          S+   G        + K++  ++K +SK          +  VQ
Sbjct: 327 KNQTFSRGGRQTEQRNNSQDEDGFQELNENGNAKDENIQQKLSSKVLDDLPENSPINIVQ 386

Query: 399 EP-------PRIEDAEEFPNLAVASERRDRIETPKFQSKQQPQDNFKNNVKKSQLPVQLD 451
            P       P+   +++   LA A            + K+  +   K   KK++ PVQLD
Sbjct: 387 TPIPITTSVPKRAKSQKKKALAAALATAQEYSEISMEQKKLQEALSKAAGKKNKTPVQLD 446

Query: 452 LGGMLTALEKKQHSQHAKQSSKPVVVSVGAVPVLSKECASGERGRRMSQMK---TPHNPL 508
           LG ML ALEK+Q +  A+Q +    +S   V   S         + +++ +   T  N +
Sbjct: 447 LGDMLAALEKQQQAMKARQITNTRPLSYTVVTAASFHTKDSTNRKPLTKSQPCLTSFNSV 506

Query: 509 DSSAPLMKKGKQREIPKAKKPTSLKKIILKERQERKQRLQENAVSPAFTSDDTQDGESGG 568
           D ++   KKGK++EI K K+PT+LKK+ILKER+E+K RL  +       S++  +     
Sbjct: 507 DIASSKAKKGKEKEIAKLKRPTALKKVILKEREEKKGRLTVD--HNLLGSEEPTEMHLDF 564

Query: 569 DDQFPEQAELSGPEGMDELISTPSVEDKSEEPPG--TELQRDTEASHLAPN---HTTFPK 623
            D  P++       G+  + S  S+   S+  P   T + + + AS    +    +T  K
Sbjct: 565 IDDLPQEIVSQEDTGLS-MPSDTSLSPASQNSPYCMTPVSQGSPASSGIGSPMASSTITK 623

Query: 624 IHSRRFRDYCSQMLSKEVDACVTDLLKELVRFQDRMYQKDPVKAKTKRRLVLGLREVLKH 683
           IHS+RFR+YC+Q+L KE+D CVT LL+ELV FQ+R+YQKDPV+AK +RRLV+GLREV KH
Sbjct: 624 IHSKRFREYCNQVLCKEIDECVTLLLQELVSFQERIYQKDPVRAKARRRLVMGLREVTKH 683

Query: 684 LKLKKLKCVIISPNCEKIQSKGGLDDTLHTIIDYACEQNIPFVFALNRKALGRSLNKAVP 743
           +KL K+KCVIISPNCEKIQSKGGLD+ L+ +I  A EQ IPFVFAL RKALGR +NK VP
Sbjct: 684 MKLNKIKCVIISPNCEKIQSKGGLDEALYNVIAMAREQEIPFVFALGRKALGRCVNKLVP 743

Query: 744 VSVVGIFSYDGAQDQFHKMVELTVAARQAYKTMLENVQQELVGEPRPQAP---------- 793
           VSVVGIF+Y GA+  F+K+VELT  AR+AYK M+  ++QE   E                
Sbjct: 744 VSVVGIFNYFGAESLFNKLVELTEEARKAYKDMVAAMEQEQAEEALKNVKKVPHHMGHSR 803

Query: 794 -PSLPTQGPSCPAEDGPPALKEKEEPHYIEIWKKHLEAYSGCTL---ELEESLEASTSQ 848
            PS  +    C     P  + E  E  Y   W+  +E   G      E E S + STS+
Sbjct: 804 NPSAASAISFCSVISEP--ISEVNEKEYETNWRNMVETSDGLEASENEKEVSCKHSTSE 860


>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
           [Homo sapiens]
          Length = 651

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 88/494 (17%), Positives = 179/494 (36%), Gaps = 50/494 (10%)

Query: 142 LFKKKTYDEKKTYDQQKFDSERADGTISSEIKSARGSHHLSIYAENSLKSDGYHKRTDRK 201
           L+  KT+ +K  Y + K   E+    +  + K   GS+  +  ++  ++     +    K
Sbjct: 103 LYTSKTHLKKAEYKKSK--DEKGGTPLKKDSKKKGGSYATNPESKQIVEEKTKRQNEADK 160

Query: 202 SRIIAKNVSTSKPEFEFTTLDFPELQGAENNMSEIQKQPKWGPVHSVSTDISLLREVVKP 261
           + + + + +    + + ++   PE Q ++       ++ K    +S  T+   L     P
Sbjct: 161 TPLKSSHENEQSKKSKSSSETNPESQNSKTVSKNCSQKDKKDSKNSKKTNTEFLHTKNNP 220

Query: 262 AAVLSKG--------EIVVKNNPNESVTANAATNSPSCTRELSW-------TPMGYVVRQ 306
              L +         EI  +N+ N         +        +W           Y ++ 
Sbjct: 221 KKDLKRSKTSNDPISEICSENSLNVDFLMLVGQSDDESINFDAWLRNYSQNNSKNYSLKY 280

Query: 307 TLSTELSAAPKNVTSMINLKTIASSADPKNVSIPSSEALSSDPSYNKEKHIIHPTQKSKA 366
           T  T+     K+        + A S D K+    S +   +    +K+K +   T+ + A
Sbjct: 281 TKYTK-----KDTKKNAKKSSDAESEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTESTDA 335

Query: 367 SQGSDLEQNEASRKNKKK-----KEKSTSKYEVLTVQEPPRIEDA-EEFPNLAVASERRD 420
             G   ++ + ++K+KKK     K+K T KY   T  E    +DA  +  NL  AS+  D
Sbjct: 336 ESGDSKDERKDTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDD 395

Query: 421 RIETPK---FQSKQQPQDNFKNNVKKSQLPVQLDLGGMLTALEKKQHSQHAKQSSKPVVV 477
           + +  K   F +  + +   K + K                 EKK        + K V  
Sbjct: 396 KKKDAKKITFSTDSESELESKESQKD----------------EKKDKKDSKTDNKKSVKN 439

Query: 478 SVGAVPVLSKECASGERGRRMSQMKTPHNPLDSSAPLMKKGKQREIPKAKKPTSLKKIIL 537
              +    S+     ++G++  +     +  D      KK  +    ++       K   
Sbjct: 440 DEESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKDAKKNAESTEMESDLELKKDKKHS 499

Query: 538 KERQERKQRLQENAVSPAFTSDDTQDGESGGDDQFPEQAELSGPE-GMDELISTPSVEDK 596
           KE++  K+ ++++A     ++D   D  S     F    ++ G +   +E +  P  + K
Sbjct: 500 KEKKGSKKDIKKDARKDTESTDAEFDESS--KTGFKTSTKIKGSDTESEESLYKPGAKKK 557

Query: 597 SEEPPGTELQRDTE 610
            +E  GT      E
Sbjct: 558 IDESDGTSANSKME 571



 Score = 33.1 bits (74), Expect = 1.1
 Identities = 52/226 (23%), Positives = 81/226 (35%), Gaps = 12/226 (5%)

Query: 309 STELSAAPKNVTSMINLKTIASSADPKNVSIPSSEALSSDPSYNKEKHIIHP--TQKSKA 366
           S  L  A KN     + K I  S D ++  + S E+   +    K+    +    +  + 
Sbjct: 384 SRNLKKASKNDDKKKDAKKITFSTDSES-ELESKESQKDEKKDKKDSKTDNKKSVKNDEE 442

Query: 367 SQGSDLEQNEASRKNKK--KKEKSTSKYEVLTVQEPPRIEDAEEFPNLAVASERRDRIET 424
           S  +D E    S+K KK  KK K  SK +          E  E   +L +  +++   E 
Sbjct: 443 STDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKDAKKNAESTEMESDLELKKDKKHSKEK 502

Query: 425 PKFQSKQQPQDNFKNNVKKSQLPVQLDLGGMLTALEKKQHSQHAKQS------SKPVVVS 478
            K   K   +D  K+         +    G  T+ + K     +++S       K +  S
Sbjct: 503 -KGSKKDIKKDARKDTESTDAEFDESSKTGFKTSTKIKGSDTESEESLYKPGAKKKIDES 561

Query: 479 VGAVPVLSKECASGERGRRMSQMKTPHNPLDSSAPLMKKGKQREIP 524
            G       E    +RG RMS  KT  N     A   +    RE P
Sbjct: 562 DGTSANSKMEGLESKRGFRMSSKKTTFNEKGEKASTGRVPPSREKP 607


>gi|193788653 hypothetical protein LOC100131897 [Homo sapiens]
          Length = 535

 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 41/142 (28%), Positives = 58/142 (40%), Gaps = 9/142 (6%)

Query: 331 SADPKNVSIPSSEALSSDPSYNKEKHIIHPTQKSKASQGSDLEQNEASRKNKKKKEKSTS 390
           S+  K   +PSS    S PS        HP + S     S+  QN  S K      KS  
Sbjct: 294 SSQSKETCVPSSPRTHSSPSQGSHSQPAHPGRASDCPSSSNNHQNLVSLKT-NSASKSAP 352

Query: 391 KYEVLTVQEPPRIEDAEEFPNLAVAS---ERRDRIETPKFQSKQQPQDNFKNNVKKSQLP 447
             +  T   P    D  EFPN   ++       R ET K QS ++  D  + ++ + +L 
Sbjct: 353 GCQEQTANNPTE-SDTLEFPNCPGSNHLPSSLSRSET-KLQSNREISDINQIHLARGEL- 409

Query: 448 VQLDLGGMLTALEKKQHSQHAK 469
              DL G L ++E+  HS   K
Sbjct: 410 --CDLQGRLQSVEESLHSNQEK 429


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 43.9 bits (102), Expect = 6e-04
 Identities = 89/478 (18%), Positives = 178/478 (37%), Gaps = 59/478 (12%)

Query: 178 SHHLSIYAENSLKSDGYHKRTDRKSRIIAKNVS--------TSKPEFEFTTLDFPELQGA 229
           S H+ + +E  +K     +++++++ I+ +           T + E E    +  E +G 
Sbjct: 433 STHIKVKSEEKIK---VVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGG 489

Query: 230 ENNMSEI-QKQPKWGPVHSVSTDISLLREVVKPAAVLSKGEIVVKNNPNESVTANAATNS 288
           E   +E  +++ K  P    +   S  +E   P    +K     K+   E   + A   S
Sbjct: 490 EEEEAEGGEEETKSPPAEEAA---SPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKS 546

Query: 289 PSCTRELSWTPMGYVVRQTLSTELSAAPKNVTSMINLKTIASSADPKNVSIPSSEALSSD 348
           P    E + +P      +  S   + +P+   +    K+ A    P+    P+ E   S 
Sbjct: 547 P----EKAKSP---AKEEAKSPPEAKSPEKEEA----KSPAEVKSPEKAKSPAKEEAKSP 595

Query: 349 P---SYNKEKHIIHPTQKSKASQGSDLEQNEASRKNKKKKEKSTSKYEVLTVQEPPRIED 405
               S  K K  +    KS A   S +++   S    K  EK+ S          P  E+
Sbjct: 596 AEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKS----------PTKEE 645

Query: 406 AEEFPNLAVASERRDRIETPKFQSKQQPQDNFKNNVKKSQLPVQLDLGGMLTALEKKQHS 465
           A+  P  A + E+ +     K +S  + +     + +K++ PV+ +      A    +  
Sbjct: 646 AKS-PEKAKSPEKEEAKSPEKAKSPVKAE---AKSPEKAKSPVKAEAKSPEKAKSPVKEE 701

Query: 466 QHAKQSSKPVVVSVGAVPVLSKECASGERGRRMSQMKTP-----HNPLDSSAPLMKKGKQ 520
             + + +K  V      P  +K     E  +   + K+P      +P  + +P   K   
Sbjct: 702 AKSPEKAKSPVKEEAKSPEKAKSPVK-EEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLD 760

Query: 521 REIPKAKKPTS--LKKIILKERQERKQRLQENAVSPAFTSDDTQDGESGGDDQFPEQAEL 578
            + P+AK P     +    K  ++ K  ++E   SP       ++     + + P++ E+
Sbjct: 761 VKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEV 820

Query: 579 SGPEGMDELISTPSV--------EDKSEEPPGTELQRDTEASHLAPNHTTFPKIHSRR 628
             P   +E      V        E+K+   P TE ++D++           PK+  ++
Sbjct: 821 KSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKK 878



 Score = 43.5 bits (101), Expect = 8e-04
 Identities = 82/444 (18%), Positives = 163/444 (36%), Gaps = 52/444 (11%)

Query: 197 RTDRKSRIIAKNVSTSKPEFEFTTLDFP----ELQGAENNMSEIQKQPKWGPVHSVSTDI 252
           ++  K++  AK  + S PE +    +      E++  E   S  +++ K  P  + S + 
Sbjct: 545 KSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAK-SPAEAKSPE- 602

Query: 253 SLLREVVKPAAVLSKGEIVVKNNPNESVTANAATNSP----SCTRELSWTPMGYVVRQTL 308
               +   P    +K     K+   E   + A   SP    S T+E + +P      ++ 
Sbjct: 603 ----KAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEK---AKSP 655

Query: 309 STELSAAPKNVTSMINLKTIASSADPKNVSIP-SSEALSSDPSYNKEKHIIHPTQKSKAS 367
             E + +P+   S +     A +  P+    P  +EA S + + +  K      +K+K+ 
Sbjct: 656 EKEEAKSPEKAKSPVK----AEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSP 711

Query: 368 QGSDLEQNEASRKNKKKKEKSTSKYEVLTVQEPPRIEDAEEFPNLAVASERRDRIETPKF 427
              + +  E ++   K++ K+  K +    +E    E A+          +    +TP  
Sbjct: 712 VKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAK 771

Query: 428 QSKQQPQDNFKNNVK-----------KSQLPVQLDLGGMLTALEKKQH-SQHAKQSSKPV 475
           +  + P D F    K           K++ P++ D       + KK+      K+  KP 
Sbjct: 772 EEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQ 831

Query: 476 VVSVGAVPVLSKECASGERGRRMSQMKTPHNPLDSSAPLMKKGKQREIPKAKKPTSLKKI 535
            V V   P  ++E  +    +   +  +             K ++++ P  +KP   K  
Sbjct: 832 EVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVE 891

Query: 536 ILKERQERKQRL---QENAVSPAFTSDDTQ------------DGESGGDDQFPEQAELSG 580
             KE  E K+++   ++ A +     +D +            D     +   P + + + 
Sbjct: 892 AKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAA 951

Query: 581 PEGMDELISTPSVEDKSEEPPGTE 604
           PE  D   +      K EE P TE
Sbjct: 952 PEKKD---TKEEKAKKPEEKPKTE 972


>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
          Length = 2468

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 57/269 (21%), Positives = 107/269 (39%), Gaps = 38/269 (14%)

Query: 304 VRQTLSTELSAAPKNVTSMINLKTIASSADPKNVSIPSSEALSSDPSYNKEKHIIHPTQK 363
           ++Q L+T+     +  T ++    +   AD +    P+++ L S  S  KE     P + 
Sbjct: 511 LKQPLATQKDLTGQVPTPVVKQTKLKQRADSRESLKPAAKPLPSK-SVRKESKEETP-EV 568

Query: 364 SKASQGSDLEQNEASRKNKKKKEK--------STSKYEVLTVQEPPRIEDAEEFPNLAVA 415
           +K +      + E+  K   KK+K        S ++ EV + +EP  ++           
Sbjct: 569 TKVNHVEKPPKVESKEKVMVKKDKPIKTETKPSVTEKEVPSKEEPSPVKAEVAEKQATDV 628

Query: 416 SERRDRIETPKFQSKQQPQDNF---------------KNNVKKSQLP----VQLDLGGML 456
             +  + +T K ++K +P+D                 K  +KK + P    V+ ++   +
Sbjct: 629 KPKAAKEKTVKKETKVKPEDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEI 688

Query: 457 TALEKKQHSQHAKQSSKPVVVSVGAVPVLSKECASGERGRRMSQMKTPHNPLDSSAPLMK 516
              EKK+  +  K+ + P  V         KE    E+  +    K P +   SS PL  
Sbjct: 689 KKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPKKEIKKLPKDAKKSSTPL-- 746

Query: 517 KGKQREIPKAKKPTSLKKIILKERQERKQ 545
                   +AKKP +LK  + K+ +  K+
Sbjct: 747 -------SEAKKPAALKPKVPKKEESVKK 768


>gi|110349788 absent, small, or homeotic 1-like [Homo sapiens]
          Length = 2964

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 111/565 (19%), Positives = 197/565 (34%), Gaps = 104/565 (18%)

Query: 178  SHHLSIYAENSLKSDGYHKRTDRKSR-------IIAKNVSTSKPEF--EFTTLDFPELQG 228
            S  LS   ++S  S  + K   R+++        + K +   + E   E T +       
Sbjct: 449  SQELSESLKDSATSKTFEKNVVRQNKESILEKFSVRKEIINLEKEMFNEGTCIQQDSFSS 508

Query: 229  AENNMSEIQKQPKWGPVHSVSTDISL-----LREVVKPAAVLSKGEIVVKNNPNESVTAN 283
            +E    E  K  K  PV+  S D  +     +     P + + +  +    +P+ +V+ N
Sbjct: 509  SEKGSYETSKHEKQPPVYCTSPDFKMGGASDVSTAKSPFSAVGESNLP---SPSPTVSVN 565

Query: 284  AATNSPSCTR-ELSWTPM----------------GYVVRQTLSTELSAAPKNVTSMINLK 326
              T SP  T  +L+  P+                G     + ST L+   ++V   I+++
Sbjct: 566  PLTRSPPETSSQLAPNPLLLSSTTELIEEISESVGKNQFTSESTHLNVGHRSVGHSISIE 625

Query: 327  TIA-----SSADPKNVSIPS-SEALSSDPSYNKEK--HIIHPTQ-------------KSK 365
                    + +   ++ IP  S +L   PS   E   H I P+              K  
Sbjct: 626  CKGIDKEVNDSKTTHIDIPRISSSLGKKPSLTSESSIHTITPSVVNFTSLFSNKPFLKLG 685

Query: 366  ASQGSDLE-----------QNEASRKNKKKKEKSTSKYEVLTVQEPP--RIEDAEEFPNL 412
            A   SD             Q++  +K K +K + T      T + P    +E +E F N+
Sbjct: 686  AVSASDKHCQVAESLSTSLQSKPLKKRKGRKPRWTKVVARSTCRSPKGLELERSELFKNV 745

Query: 413  AVASERRDRIETPKFQSKQQPQDNFKNNVKKSQLPVQLDLG-----GMLTALEKKQHSQH 467
            + +S      E  KF     P     ++  K +LP +L         +L   EK  H   
Sbjct: 746  SCSSLSNSNSEPAKFMKNIGPPSFVDHDFLKRRLP-KLSKSTAPSLALLADSEKPSHKSF 804

Query: 468  AKQS-SKPVVVSVGAVPVLSKECASGERGRRMSQMKTPHN-----PLDSSAPLMKKGKQR 521
            A    S  + VS   +  + K      + + M Q++ P       P      L  K +Q 
Sbjct: 805  ATHKLSSSMCVSSDLLSDIYKPKRGRPKSKEMPQLEGPPKRTLKIPASKVFSLQSKEEQE 864

Query: 522  --------EIPKAKKPTSLKKIILKERQERKQRLQENAVSPAFTS-------------DD 560
                    EIP  K+  S+     K  + ++Q      + P   S             + 
Sbjct: 865  PPILQPEIEIPSFKQGLSVSPFPKKRGRPKRQMRSPVKMKPPVLSVAPFVATESPSKLES 924

Query: 561  TQDGESGGDDQFPEQAELSGPEGMDELISTPSVEDKS--EEPPGTELQRDTEASHLAPNH 618
              D      D F  + +L  P+ +D+    PSV   S  E  P  ++ +      +    
Sbjct: 925  ESDNHRSSSDFFESEDQLQDPDDLDD-SHRPSVCSMSDLEMEPDKKITKRNNGQLMKTII 983

Query: 619  TTFPKIHSRRFRDYCSQMLSKEVDA 643
                K+ + + +   +Q+LS  V++
Sbjct: 984  RKINKMKTLKRKKLLNQILSSSVES 1008



 Score = 30.4 bits (67), Expect = 7.3
 Identities = 62/275 (22%), Positives = 106/275 (38%), Gaps = 48/275 (17%)

Query: 303 VVRQTLSTELSAAPKNVTSMINLKTIASSA--------DPKNVSIPSSEALSSDPSYNKE 354
           +V + L  +L +    V      K +ASSA          K +S P +  +S D + N +
Sbjct: 367 LVNKDLGKKLGSTVGLVAKDCAKKIVASSAMGLVNKDIGKKLMSCPLAGLISKD-AINLK 425

Query: 355 KHIIHPTQKS-KASQGSDLEQNEASRKNKKKKEKSTSKYEVLTVQEPPRIEDAEEFPNLA 413
              + PTQ+  KAS  +++   E+   ++  K+ +TSK     V    +    E+F    
Sbjct: 426 AEALLPTQEPLKASCSTNINNQESQELSESLKDSATSKTFEKNVVRQNKESILEKF---- 481

Query: 414 VASERRDRIETPKFQSKQQ---PQDNFKNNVKKSQLPVQLDLGGMLTALEKKQHSQHAKQ 470
             S R++ I   K    +     QD+F ++ K S                  + S+H KQ
Sbjct: 482 --SVRKEIINLEKEMFNEGTCIQQDSFSSSEKGSY-----------------ETSKHEKQ 522

Query: 471 ----SSKPVVVSVGAVPVLSKECASGERGRRMSQMKTPHNPLDSSAPLMKKGKQREIPKA 526
                + P     GA  V + +      G   S + +P +P  S  PL      R  P+ 
Sbjct: 523 PPVYCTSPDFKMGGASDVSTAKSPFSAVGE--SNLPSP-SPTVSVNPL-----TRSPPET 574

Query: 527 KKPTSLKKIILKERQERKQRLQENAVSPAFTSDDT 561
               +   ++L    E  + + E+     FTS+ T
Sbjct: 575 SSQLAPNPLLLSSTTELIEEISESVGKNQFTSEST 609


>gi|197927454 DEK oncogene isoform 2 [Homo sapiens]
          Length = 341

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 55/268 (20%), Positives = 97/268 (36%), Gaps = 47/268 (17%)

Query: 343 EALSSDPSYNKEKHIIHPTQKSKASQGSDLEQNEASRKNK---------------KKKEK 387
           E   + P+  KE  +  P ++S+  +  D E+ E   K K               KKK  
Sbjct: 11  EGTPTQPASEKEPEMPGPREESEEEEDEDDEEEEEEEKGKGQKLCEIERIHFFLSKKKTD 70

Query: 388 STSKYEVLTVQEPPRIEDAEEFPNLAVASERRDRIETPKFQSKQQPQDNFKNNVKKSQLP 447
                  L    P  +   ++  N+   S       + +++ K++    F+N + KS   
Sbjct: 71  ELRNLHKLLYNRPGTVSSLKK--NVGQFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSICE 128

Query: 448 V-QLDLGGMLTALEKK--QHSQHAKQSSKPVVVS-----------------------VGA 481
           V  L+  G+ + L K+      H K S KP+  S                          
Sbjct: 129 VLDLERSGVNSELVKRILNFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKC 188

Query: 482 VPVLSKECASGERGRRMSQMKTPHNPLDSSAPLMKKGKQREIPKAKKPTSLKKII----L 537
             +LS E +S E  ++  +  +     +S     KK  +RE PK K  +  KK +    +
Sbjct: 189 PEILSDESSSDEDEKKNKEESSDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANV 248

Query: 538 KERQERKQRLQENAVSPAFTSDDTQDGE 565
           K+      +  +N+      S+D+ D E
Sbjct: 249 KKADSSTTKKNQNSSKKESESEDSSDDE 276



 Score = 39.3 bits (90), Expect = 0.016
 Identities = 34/159 (21%), Positives = 71/159 (44%), Gaps = 5/159 (3%)

Query: 334 PKNVSIPSSEALSSDPSYNKEKHIIHPTQKSKASQGSDLEQNEAS--RKNKKKKEKSTSK 391
           P    +P S+   S  S  KE++     +K+K ++  ++  +E+S     KK KE+S+  
Sbjct: 154 PSGKPLPKSKKTCSKGS-KKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDD 212

Query: 392 YEVLTVQEPPRIEDAEEFPNLAVASERRDRIETP--KFQSKQQPQDNFKNNVKKSQLPVQ 449
            +  + +EPP+     E P     S+ +  +++   K       + N  ++ K+S+    
Sbjct: 213 EDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDS 272

Query: 450 LDLGGMLTALEKKQHSQHAKQSSKPVVVSVGAVPVLSKE 488
            D   ++  L+K    +  K++ K ++ S     V  K+
Sbjct: 273 SDDEPLIKKLKKPPTDEELKETIKKLLASANLEEVTMKQ 311


>gi|56676335 RAP1 interacting factor 1 [Homo sapiens]
          Length = 2472

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 61/300 (20%), Positives = 120/300 (40%), Gaps = 32/300 (10%)

Query: 318  NVTSMINLKTIASSADPKNVSIPSSEALSSDPSYNKEKHIIHPTQKS-----KASQGSDL 372
            N++S + +K    +   K   +P ++      S +  + I++ T++S     KA Q  + 
Sbjct: 1242 NISSTVTVKNNQETMI-KTDFLPKAKQREGTFSKSDSEKIVNGTKRSSRRAGKAEQTGNK 1300

Query: 373  EQNEASRKNKKKKEKSTSKYEVLTVQEPPRIEDAEEFPNLAVASERRDRIETPKFQSKQQ 432
                  R   +K  + + +  V+    PP + +  E       S+ +  +     +    
Sbjct: 1301 RSKPLMRSEPEKNTEESVEGIVVLENNPPGLLNQTE-----CVSDNQVHLSESTME---- 1351

Query: 433  PQDNFKNNVKKSQLPVQLDLGGMLTALEKK-QHSQHAKQSSKPVVVSV-------GAVPV 484
              DN K      +  V L+     T  EK  + +  +K+++ PVV+S          V +
Sbjct: 1352 -HDNTKLKAATVENAVLLETN---TVEEKNVEINLESKENTPPVVISADQMVNEDSQVQI 1407

Query: 485  LSKECASGERGRRMSQM---KTPHNPLDSSAPLMKKGKQREIPKAKKPTSLKKIIL-KER 540
               +       RR S++    T     ++S    ++ K+ E P  K P  +K  +L K++
Sbjct: 1408 TPNQKTLRRSSRRRSEVVESTTESQDKENSHQKKERRKEEEKPLQKSPLHIKDDVLPKQK 1467

Query: 541  QERKQRLQENAVSPAFTSDDTQDGESGGDDQFPEQAELSGPEGM-DELISTPSVEDKSEE 599
               +Q LQEN +       +   GE+  + +  +  + + PE +  E   T  + DKS E
Sbjct: 1468 LIAEQTLQENLIEKGSNLHEKTLGETSANAETEQNKKKADPENIKSEGDGTQDIVDKSSE 1527


>gi|84043963 eukaryotic translation initiation factor 5B [Homo
           sapiens]
          Length = 1220

 Score = 41.2 bits (95), Expect = 0.004
 Identities = 46/232 (19%), Positives = 88/232 (37%), Gaps = 35/232 (15%)

Query: 343 EALSSDPSYNKEKHIIHPTQKSKASQGS-----DLEQNEASRKNKKKKEKSTSKYEVLTV 397
           E ++  P+ N E+      +K K  +G      D +  E   K+ K K+ +  K E+ + 
Sbjct: 77  ETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSG 136

Query: 398 QEPPRIEDAEEFPNLAVASERRDRIETPKFQSKQQPQDNFKNNVKKSQLPVQLDLGGMLT 457
            +     D ++F  L   ++ + +    K+   ++ +DN K   ++S++    + G    
Sbjct: 137 SD-----DDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESD 191

Query: 458 ALEKKQHSQHAKQSSKPVV----------VSVGAVPVLSKECASGERGRRMSQMKTPHNP 507
              + +  Q   Q +KP             S     V  K+    ER R+          
Sbjct: 192 EFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRD------- 244

Query: 508 LDSSAPLMKKGKQREIPKAKKPTSLKKIILKERQERKQRLQENAVSPAFTSD 559
            +  A L K  ++ E+   KK  S +K       E +++ +E  V    T D
Sbjct: 245 -EEKAKLRKLKEKEELETGKKDQSKQK-------ESQRKFEEETVKSKVTVD 288



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 59/307 (19%), Positives = 118/307 (38%), Gaps = 57/307 (18%)

Query: 326 KTIASSADPKNVSIPSSEALSSDPSYNKEKHIIHPTQKSKASQGSDLEQNEASRKNKKKK 385
           +T+ S        IP+SE  +  P+  ++ +     +K K  +  + E+ E      K+K
Sbjct: 279 ETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKE------KEK 332

Query: 386 EKSTSKYEVLTVQEP-PRIEDAEE------------FPNLAVASERRDRIETPKFQSKQQ 432
           +K  SK  V  +QE   ++++ EE               L    +  +R+E  K + K+Q
Sbjct: 333 KKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQ 392

Query: 433 PQDNFKNNVKKSQLPVQLDLGGMLTALEKKQHSQHAKQSSKPVVVSVGAVPVLSKECASG 492
            +   K  +KK         G +LT   K Q    A+  +   ++    V V SK+    
Sbjct: 393 KEKERKERLKKE--------GKLLT---KSQREARARAEATLKLLQAQGVEVPSKD---- 437

Query: 493 ERGRRMSQMKTPHNPLDSSAPLMKKGKQREIP---KAKKPTSLKKIILKERQERKQRLQE 549
                          L    P+ +  K+++IP   ++K+ +   ++        +   ++
Sbjct: 438 --------------SLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEK 483

Query: 550 NAVSPAFTSDDTQDGESGGDDQF------PEQAELSGPEGMDELISTPSVEDKSEEPPGT 603
               P    ++ +D E  G D +       E  ++ G +   E+   P  E++ EE    
Sbjct: 484 EETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEE 543

Query: 604 ELQRDTE 610
           + + + E
Sbjct: 544 DEESEEE 550



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 45/235 (19%), Positives = 90/235 (38%), Gaps = 24/235 (10%)

Query: 326 KTIASSADPKNVSIPSSEALSSDPSYNKEKHIIHPTQKSKASQGSDLEQNEASRKNKKKK 385
           K     A   N     SE    +    KE+  I+ + +S       L+  +  +KN+K K
Sbjct: 148 KKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNK 207

Query: 386 EKSTSKYEVLTVQEPPRIEDAEEFPNLAVASERRDRIETPKFQSKQQPQDNFKNNVKKSQ 445
                          P IE   E  + +   +   + +  K + +++ +D  K  ++K +
Sbjct: 208 -------------PGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLK 254

Query: 446 LPVQLDLGGMLTALEKKQHSQHAKQSSK-PVVVSVGAVPVLSKECAS-------GERGRR 497
              +L+ G    + +K+   +  +++ K  V V  G +P   ++  +        E  ++
Sbjct: 255 EKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKK 314

Query: 498 MSQMKTPHNPLDSSAPLMKKGKQREIPKAKKPTSLKKIILKERQERKQRLQENAV 552
               K      +      KKG  +   KA +    K   LKE +ER++R +E  +
Sbjct: 315 KKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAK---LKEEEERQKREEEERI 366


>gi|239753245 PREDICTED: similar to UPF0634 protein C [Homo sapiens]
          Length = 710

 Score = 40.8 bits (94), Expect = 0.005
 Identities = 90/482 (18%), Positives = 179/482 (37%), Gaps = 57/482 (11%)

Query: 160 DSERADGTISSEIKSARGSHHLSIYAENSLKSDGYHKRT------DRKSRIIAKNVSTSK 213
           D E +   I++EIK    S  +S   + +LK+    K +      ++K   I++ VS+ K
Sbjct: 207 DEEGSVSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQK 266

Query: 214 PEFEFTTLDFPELQGA---ENNMSEIQKQPKWGPV-HSVSTD----ISLLREVVKPAAVL 265
           P         P L+     E+++  I ++ K G    +VS D    +   R+       +
Sbjct: 267 P---------PALKATSVKEDSVLNIAREKKDGEKSRTVSFDQPPGLKATRDEKDSLLNI 317

Query: 266 SKGE--------IVVKNNPNESVTANAATNSPSCTRELSWTPMGYVVRQTLSTELSAAPK 317
           ++G+        +  +  P    T++   +  + TR      +   V       L     
Sbjct: 318 ARGKKNGEKTRRVSSRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSD 377

Query: 318 NVTSMINL---------KTIASSADPKNVSIPSSEA-----LSSDPSYNKEKHIIHPTQK 363
              S++ +             SS  P  +   S E      ++    Y ++   +   +K
Sbjct: 378 EEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKK 437

Query: 364 SKASQGSDLEQNEASRKNKKKKEKSTSKYEVLTVQEPPRIEDA--EEFPNLAVASERRDR 421
                 SD E++  S   ++KK+   S+   ++ Q+PP ++    EE   L +A E +D 
Sbjct: 438 PSLEATSD-EKDSFSNITREKKDGEISRK--VSSQKPPALKGTSDEEDSVLGIARENKDG 494

Query: 422 IETPKFQSKQQPQDNFKNNVKKSQLPVQLDLGGMLTALEKKQHSQHAKQSSKPVVVSVGA 481
            ++    S++ P     ++ K S L +     G     + +  S   K + K       +
Sbjct: 495 EKSRTVSSEKPPGLKATSDEKDSVLNIAR---GKKDGEKTRTVSSRKKPALKATSDEKDS 551

Query: 482 VPVLSKECASGERGRRMSQMKTPHNPLDSSAPLMKKGKQREIPKAKKPTSLKKIILKERQ 541
           V  +++E   GE+ R +S  K P       A   K+     +   KK   +   +  ++Q
Sbjct: 552 VLYIAREKKDGEKSRTVSSQKQP----ALKAICDKEDSVPNMATEKKDEQISGTVSSQKQ 607

Query: 542 ERKQRLQENAVSPAFTSDDTQDGESGGDDQFPEQAELSGPEGMDELISTPSVEDKSEEPP 601
              +   +   S +    + +DG+  G     +Q          + +S  + E K  +  
Sbjct: 608 PALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIR 667

Query: 602 GT 603
           GT
Sbjct: 668 GT 669



 Score = 31.2 bits (69), Expect = 4.3
 Identities = 39/186 (20%), Positives = 76/186 (40%), Gaps = 11/186 (5%)

Query: 362 QKSKASQGSDLEQNEASRKNKKKKEKSTSKYEVLTVQEPPRIEDAEEFPNLAVASERRDR 421
           QK  A + +  E++  S    + KE   S       Q   ++   ++   L +A+     
Sbjct: 95  QKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRIMGG 154

Query: 422 IETPKFQSKQQPQDNFKNNVKKSQLPVQLDLGGMLTALEKKQHSQHAKQSSKPVVVSVGA 481
            ++    S++QP     ++   S L    ++      L+    S   +Q+ K      G+
Sbjct: 155 GKSGTVSSQKQPASKTASDKTDSALNTATEIKD---GLQCGTVSSQKQQALKATTDEEGS 211

Query: 482 VPVLSKECASGERGRRMSQMKTP-----HNPLDSSAPLMKKGKQREIPK---AKKPTSLK 533
           V  ++ E   GE+   +S  K P      +  DS + + ++ K  EI +   ++KP +LK
Sbjct: 212 VSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALK 271

Query: 534 KIILKE 539
              +KE
Sbjct: 272 ATSVKE 277


>gi|117553580 adaptor-related protein complex 3, delta 1 subunit
           isoform 2 [Homo sapiens]
          Length = 1153

 Score = 40.4 bits (93), Expect = 0.007
 Identities = 51/242 (21%), Positives = 100/242 (41%), Gaps = 31/242 (12%)

Query: 372 LEQNEASRKNKKKKEKSTSKYEVLTVQEPPRIEDAEEFPNLAVASERRDRIETPKFQSKQ 431
           LE+++  +K K+K++K   ++  L  +    I  A++   + + +E       P  +  +
Sbjct: 737 LEKDKRRKKRKEKEKKGKRRHSSLPTESDEDIAPAQQ---VDIVTEEMPENALPSDEDDK 793

Query: 432 QPQDNFKNNVKKSQLPVQLDLGGMLTALEKKQHSQHAK-QSSKPVVVSVGAVPVLSKECA 490
            P D ++         + +DL   L   EK    +H   ++SK     V  V   SK+  
Sbjct: 794 DPNDPYR--------ALDIDLDKPLADSEKLPIQKHRNTETSKSPEKDVPMVEKKSKKPK 845

Query: 491 SGERGRRMSQMKTPHNPLDSSAPLMKKGKQREIPKAKKPTSLKKIILKERQERKQRLQEN 550
             E+  +  +                K K++E  K K P   KK   KE++ER +  +++
Sbjct: 846 KKEKKHKEKERD--------------KEKKKEKEKKKSPKPKKKKHRKEKEERTKGKKKS 891

Query: 551 AVSPAFTSDDTQDGESGGDDQFPEQAELSGPEGMDELISTPSVEDKSEEPPGTELQRDTE 610
              P  + +   +    G    PE+ +L  PE    L++  S    + +  G+ LQ D++
Sbjct: 892 KKQPPGSEEAAGEPVQNG---APEEEQLP-PESSYSLLAENSYVKMTCDIRGS-LQEDSQ 946

Query: 611 AS 612
            +
Sbjct: 947 VT 948



 Score = 31.2 bits (69), Expect = 4.3
 Identities = 23/118 (19%), Positives = 49/118 (41%), Gaps = 10/118 (8%)

Query: 339 IPSSEALSSDPSYNKEKHIIHPTQKSKASQGSDLEQNEASRKNKKKKEKSTSKYEVLTVQ 398
           +P  E  S  P   ++KH      K K  +    +  +  +K  +K+++  +K +  + +
Sbjct: 834 VPMVEKKSKKPKKKEKKHKEKERDKEKKKEKEKKKSPKPKKKKHRKEKEERTKGKKKSKK 893

Query: 399 EPPRIEDAEEFPNLAVASERRDRIETPKFQSKQQPQDNFKNNVKKSQLPVQLDLGGML 456
           +PP  E+A   P    A E          + +  P+ ++    + S + +  D+ G L
Sbjct: 894 QPPGSEEAAGEPVQNGAPE----------EEQLPPESSYSLLAENSYVKMTCDIRGSL 941



 Score = 30.0 bits (66), Expect = 9.5
 Identities = 27/119 (22%), Positives = 52/119 (43%), Gaps = 4/119 (3%)

Query: 319 VTSMINLKTIASSADPKNVSIPSSEALSSD---PSYNKEKHIIHPTQKSKASQGSDLEQN 375
           VT  +    + S  D K+ + P   AL  D   P  + EK  I   + ++ S+  + +  
Sbjct: 777 VTEEMPENALPSDEDDKDPNDPY-RALDIDLDKPLADSEKLPIQKHRNTETSKSPEKDVP 835

Query: 376 EASRKNKKKKEKSTSKYEVLTVQEPPRIEDAEEFPNLAVASERRDRIETPKFQSKQQPQ 434
              +K+KK K+K     E    +E  + ++ ++ P       R+++ E  K + K + Q
Sbjct: 836 MVEKKSKKPKKKEKKHKEKERDKEKKKEKEKKKSPKPKKKKHRKEKEERTKGKKKSKKQ 894


>gi|83367077 mucin 16 [Homo sapiens]
          Length = 14507

 Score = 40.4 bits (93), Expect = 0.007
 Identities = 80/365 (21%), Positives = 130/365 (35%), Gaps = 42/365 (11%)

Query: 270  IVVKNNPNES--VTANAATNSPS-CTRELSWTPMGYVVRQ-TLSTELSAAPKNVTSMINL 325
            I VK    ES  +T  +A++SPS     L+  P  + + Q TL+ E S  P   T   +L
Sbjct: 2848 IPVKPTSAESGLLTPVSASSSPSKAFASLTTAPPTWGIPQSTLTFEFSEVPSLDTKSASL 2907

Query: 326  KTIASSADPKNVSIPSSEALSSDPSYNKEKHIIHPTQKSKASQGSDLEQNEASRKNKKKK 385
             T   S +    +IP S+A ++  S +K                   E+N  +R     K
Sbjct: 2908 PTPGQSLN----TIPDSDASTASSSLSKSP-----------------EKNPRARMMTSTK 2946

Query: 386  EKSTSKYEVLTVQEPPRIEDAEEFPNLAVASERRDRIET--PKFQSKQQPQDNFKNNVKK 443
              S S ++     E P   +    P++A    R     T  P++ S+     ++ +  K 
Sbjct: 2947 AISASSFQSTGFTETP---EGSASPSMAGHEPRVPTSGTGDPRYASESM---SYPDPSKA 3000

Query: 444  SQLPVQLDLGGMLTALEKKQHSQHAKQSSKPVVVSVGAVPVLSKECASGER------GRR 497
            S       L   LT L     +  +  SS P+ +S           AS  R      G  
Sbjct: 3001 SSAMTSTSLASKLTTLFSTGQAARSGSSSSPISLSTEKETSFLSPTASTSRKTSLFLGPS 3060

Query: 498  MSQMKTPHNPLDSSAPLMKKGKQREIPKAKKPTSLKKIILKERQERKQRLQENAVSPAFT 557
            M++       L +SA  +       + + + P       + E +      Q    +P+ T
Sbjct: 3061 MARQPNILVHLQTSALTLSPTSTLNMSQEEPPELTSSQTIAEEEGTTAETQTLTFTPSET 3120

Query: 558  SDDTQDGESGGDDQFPEQAELSGPEGMDELISTPSVEDKSEEPPGTELQRDTEASHLAPN 617
                    S  +   P     S PE     IS P+     E   GT +     +S  A  
Sbjct: 3121 PTSLLPVSSPTE---PTARRKSSPETWASSISVPAKTSLVETTDGTLVTTIKMSSQAAQG 3177

Query: 618  HTTFP 622
            ++T+P
Sbjct: 3178 NSTWP 3182



 Score = 33.1 bits (74), Expect = 1.1
 Identities = 76/358 (21%), Positives = 122/358 (34%), Gaps = 47/358 (13%)

Query: 279 SVTANAATNSPSCTRELSWTPMGYVVRQTLSTELSAAPKNVTSMINLKTIASSADPKNVS 338
           +V+  AA +SP    + S+T +  V+ +T S + S+A +  TS+           P N  
Sbjct: 654 AVSKTAAGSSPPGGTKPSYTMVSSVIPETSSLQ-SSAFREGTSL--------GLTPLNTR 704

Query: 339 IPSSEALSSDPSYNKEKHIIHPTQKSKASQGSDLEQNEASRKNKKKKEKSTSKYEVLTVQ 398
            P S        + K    I P   S +     +        +K     +T   E+ T  
Sbjct: 705 HPFSSPEPDSAGHTKISTSI-PLLSSASVLEDKVSATSTFSHHKATSSITTGTPEISTKT 763

Query: 399 EPPR-IEDAEEFPNLAVASERRDRIETPKFQSKQQPQDNFKNNVKKSQLPVQLDLGGMLT 457
           +P   +  +    N A + ER     +P        ++                 G +LT
Sbjct: 764 KPSSAVLSSMTLSNAATSPERVRNATSPLTHPSPSGEET---------------AGSVLT 808

Query: 458 ALEKKQHSQHAKQSSKPVVVSVGAVPVLSKECASGERGRRMSQMKTPHNPLDSSAPLMKK 517
                  S  A+ +  P +   G +   S E  S      +S +KT  +    S  L   
Sbjct: 809 L------STSAETTDSPNIHPTGTLTSESSESPSTLSLPSVSGVKTTFSSSTPSTHLFTS 862

Query: 518 GKQREI---PKAKKP-TSLKKIILKERQERKQRLQENAVSPAFTSDDTQDGESGGDDQFP 573
           G++ E    P   +P TS+ ++       R      +  +P F + DT    S       
Sbjct: 863 GEETEETSNPSVSQPETSVSRV-------RTTLASTSVPTPVFPTMDTWPTRSAQFSSSH 915

Query: 574 EQAELSGPEGMDELISTPSVEDKSEEPPGT----ELQRDTEASHLAPNHTTFPKIHSR 627
             +EL          ST S   K     GT    +  RDT     AP  TT+P+   R
Sbjct: 916 LVSELRATSSTSVTNSTGSALPKISHLTGTATMSQTNRDTFNDSAAPQSTTWPETSPR 973



 Score = 31.2 bits (69), Expect = 4.3
 Identities = 53/246 (21%), Positives = 91/246 (36%), Gaps = 31/246 (12%)

Query: 274   NNPNESVTANAATNSPSCTRELSWTPMGYVVRQTLSTELSAAPKNVTSMINLKTIASSAD 333
             + P    T++ + +SP  T  ++ +P        L+T    AP+ VTS I     A+S  
Sbjct: 11698 STPVSRTTSSFSHSSPDATPVMATSPRTEASSAVLTTISPGAPEMVTSQITSSGAATSTT 11757

Query: 334   PKNVS----IPSSEALSSDPSYNKEKHIIHP-TQKSKASQGS----DLEQNEASRKNKKK 384
                ++    +P + AL S           HP T+ SK    S     + +  AS   +  
Sbjct: 11758 VPTLTHSPGMPETTALLS----------THPRTETSKTFPASTVFPQVSETTASLTIRPG 11807

Query: 385   KEKSTSKYEVLTVQEPPRIEDAEEFPNLAVASERRDRIET--PKFQSKQQPQDNFKNNVK 442
              E ST+          P    +  F  L   + R D   T  P   +K  P         
Sbjct: 11808 AETSTAL---------PTQTTSSLFTLLVTGTSRVDLSPTASPGVSAKTAPLSTHPGTET 11858

Query: 443   KSQLPVQLDLGGMLTALEKKQHSQHAKQSSKPVVVSVG-AVPVLSKECASGERGRRMSQM 501
              + +P      G+L        S  A+ S+  + ++V  AV  LS    + ++ + ++  
Sbjct: 11859 STMIPTSTLSLGLLETTGLLATSSSAETSTSTLTLTVSPAVSGLSSASITTDKPQTVTSW 11918

Query: 502   KTPHNP 507
              T  +P
Sbjct: 11919 NTETSP 11924


>gi|34335264 zinc finger, MYND-type containing 8 isoform c [Homo
           sapiens]
          Length = 1135

 Score = 40.0 bits (92), Expect = 0.009
 Identities = 39/166 (23%), Positives = 64/166 (38%), Gaps = 5/166 (3%)

Query: 484 VLSKECASGERGRRMSQMKTPHNPLDSSAPLMKKGKQREIPKAKKPTSLKKIILKERQER 543
           ++SK   SG  GRR+S    P +P+ +++  +  G   E    KK TS         +E 
Sbjct: 405 LMSKPVLSGGTGRRISLSDMPRSPMSTNSS-VHTGSDVEQDAEKKATSSH---FSASEES 460

Query: 544 KQRLQENAVSPAFTSDDTQDGESGGDDQFPEQAELSGPEGMDELISTPSVEDKSEEPPGT 603
              L ++  SPA T        SG    F  Q         D+  +T S+ + + +    
Sbjct: 461 MDFLDKSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKA 520

Query: 604 ELQRDTEASHLAPNHTTFPKIH-SRRFRDYCSQMLSKEVDACVTDL 648
           E+     +  +    T  P I   R+ R      L K +++C   L
Sbjct: 521 EMDLKELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQL 566


>gi|34335262 zinc finger, MYND-type containing 8 isoform a [Homo
           sapiens]
          Length = 1188

 Score = 40.0 bits (92), Expect = 0.009
 Identities = 39/166 (23%), Positives = 64/166 (38%), Gaps = 5/166 (3%)

Query: 484 VLSKECASGERGRRMSQMKTPHNPLDSSAPLMKKGKQREIPKAKKPTSLKKIILKERQER 543
           ++SK   SG  GRR+S    P +P+ +++  +  G   E    KK TS         +E 
Sbjct: 430 LMSKPVLSGGTGRRISLSDMPRSPMSTNSS-VHTGSDVEQDAEKKATSSH---FSASEES 485

Query: 544 KQRLQENAVSPAFTSDDTQDGESGGDDQFPEQAELSGPEGMDELISTPSVEDKSEEPPGT 603
              L ++  SPA T        SG    F  Q         D+  +T S+ + + +    
Sbjct: 486 MDFLDKSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKA 545

Query: 604 ELQRDTEASHLAPNHTTFPKIH-SRRFRDYCSQMLSKEVDACVTDL 648
           E+     +  +    T  P I   R+ R      L K +++C   L
Sbjct: 546 EMDLKELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQL 591


>gi|34335266 zinc finger, MYND-type containing 8 isoform b [Homo
           sapiens]
          Length = 1160

 Score = 40.0 bits (92), Expect = 0.009
 Identities = 39/166 (23%), Positives = 64/166 (38%), Gaps = 5/166 (3%)

Query: 484 VLSKECASGERGRRMSQMKTPHNPLDSSAPLMKKGKQREIPKAKKPTSLKKIILKERQER 543
           ++SK   SG  GRR+S    P +P+ +++  +  G   E    KK TS         +E 
Sbjct: 430 LMSKPVLSGGTGRRISLSDMPRSPMSTNSS-VHTGSDVEQDAEKKATSSH---FSASEES 485

Query: 544 KQRLQENAVSPAFTSDDTQDGESGGDDQFPEQAELSGPEGMDELISTPSVEDKSEEPPGT 603
              L ++  SPA T        SG    F  Q         D+  +T S+ + + +    
Sbjct: 486 MDFLDKSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKA 545

Query: 604 ELQRDTEASHLAPNHTTFPKIH-SRRFRDYCSQMLSKEVDACVTDL 648
           E+     +  +    T  P I   R+ R      L K +++C   L
Sbjct: 546 EMDLKELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQL 591


>gi|226817313 SH3 and multiple ankyrin repeat domains 2 isoform 1
            [Homo sapiens]
          Length = 1849

 Score = 39.7 bits (91), Expect = 0.012
 Identities = 68/310 (21%), Positives = 113/310 (36%), Gaps = 60/310 (19%)

Query: 320  TSMINLKTIASSADPKNVSIPSSEALSSDPSYNKEKHIIHPTQKSKASQGSDLEQNEASR 379
            T  +++   +    P   S+P S    S  +YN  K    PT +   +      QN A+ 
Sbjct: 875  TRSLSMPDTSEDIPPPPQSVPPSPPPPSPTTYNCPKS---PTPRVYGTIKPAFNQNSAA- 930

Query: 380  KNKKKKEKSTSKYEVLTVQEPPRIEDAEEFPNLAVASERRDRIETPKFQSKQQPQDNFKN 439
                K   +T    V T+     +    E    ++ SE         +     PQ NF+N
Sbjct: 931  ----KVSPATRSDTVATMMREKGMYFRRELDRYSLDSE-------DLYSRNAGPQANFRN 979

Query: 440  NVKKSQLPVQLDLGGMLTALEKKQHSQHAKQSSKPVVVSVGAVP---VLSKECASGERGR 496
              K+ Q+P             +  +S+  K +SK V V         +L K+    +   
Sbjct: 980  --KRGQMP-------------ENPYSEVGKIASKAVYVPAKPARRKGMLVKQSNVEDSPE 1024

Query: 497  RMSQMKTP----HNPLDSSAPLMKKGKQREI-PKAKKPTSLKK-------------IILK 538
            +   +  P      P  SS+    +G   EI P+A +P S  +              I  
Sbjct: 1025 KTCSIPIPTIIVKEPSTSSSGKSSQGSSMEIDPQAPEPPSQLRPDESLTVSSPFAAAIAG 1084

Query: 539  ERQERKQRLQENAVSPAFTSDDTQDGESG--------GDDQFPEQAELSGPEGMDELIST 590
              ++R++RL+    SPAF S D  D + G            FPE+ + +  +  ++L S+
Sbjct: 1085 AVRDREKRLEARRNSPAFLSTDLGDEDVGLGPPAPRTRPSMFPEEGDFADEDSAEQL-SS 1143

Query: 591  PSVEDKSEEP 600
            P       EP
Sbjct: 1144 PMPSATPREP 1153


>gi|4503249 DEK oncogene isoform 1 [Homo sapiens]
          Length = 375

 Score = 39.3 bits (90), Expect = 0.016
 Identities = 34/159 (21%), Positives = 71/159 (44%), Gaps = 5/159 (3%)

Query: 334 PKNVSIPSSEALSSDPSYNKEKHIIHPTQKSKASQGSDLEQNEAS--RKNKKKKEKSTSK 391
           P    +P S+   S  S  KE++     +K+K ++  ++  +E+S     KK KE+S+  
Sbjct: 188 PSGKPLPKSKKTCSKGS-KKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDD 246

Query: 392 YEVLTVQEPPRIEDAEEFPNLAVASERRDRIETP--KFQSKQQPQDNFKNNVKKSQLPVQ 449
            +  + +EPP+     E P     S+ +  +++   K       + N  ++ K+S+    
Sbjct: 247 EDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDS 306

Query: 450 LDLGGMLTALEKKQHSQHAKQSSKPVVVSVGAVPVLSKE 488
            D   ++  L+K    +  K++ K ++ S     V  K+
Sbjct: 307 SDDEPLIKKLKKPPTDEELKETIKKLLASANLEEVTMKQ 345



 Score = 34.7 bits (78), Expect = 0.39
 Identities = 61/302 (20%), Positives = 108/302 (35%), Gaps = 81/302 (26%)

Query: 343 EALSSDPSYNKEKHIIHPTQKSKASQGSDLEQNEASRKNKK-----KKEKSTSKYEVLTV 397
           E   + P+  KE  +  P ++S+  +  D E+ E   K K      K+EK   K E LT+
Sbjct: 11  EGTPTQPASEKEPEMPGPREESEEEEDEDDEEEEEEEKEKSLIVEGKREKK--KVERLTM 68

Query: 398 Q------EPPRIEDAE-------EFPNLAVASERRDRIE--------------------- 423
           Q      EP  I   +       E  +  ++ ++ D +                      
Sbjct: 69  QVSSLQREPFTIAQGKGQKLCEIERIHFFLSKKKTDELRNLHKLLYNRPGTVSSLKKNVG 128

Query: 424 ----------TPKFQSKQQPQDNFKNNVKKSQLPV-QLDLGGMLTALEKK--QHSQHAKQ 470
                     + +++ K++    F+N + KS   V  L+  G+ + L K+      H K 
Sbjct: 129 QFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSICEVLDLERSGVNSELVKRILNFLMHPKP 188

Query: 471 SSKPVVVS-----------------------VGAVPVLSKECASGERGRRMSQMKTPHNP 507
           S KP+  S                            +LS E +S E  ++  +  +    
Sbjct: 189 SGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDDED 248

Query: 508 LDSSAPLMKKGKQREIPKAKKPTSLKKII----LKERQERKQRLQENAVSPAFTSDDTQD 563
            +S     KK  +RE PK K  +  KK +    +K+      +  +N+      S+D+ D
Sbjct: 249 KESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSD 308

Query: 564 GE 565
            E
Sbjct: 309 DE 310


>gi|27734775 hypothetical protein LOC286499 [Homo sapiens]
          Length = 248

 Score = 39.3 bits (90), Expect = 0.016
 Identities = 31/147 (21%), Positives = 64/147 (43%), Gaps = 17/147 (11%)

Query: 329 ASSADPKNVSIPSSEALSSDPSYNKEKHIIHPTQKSKASQGSDLEQNEASRKNKKKKEKS 388
           +SS+D  + S  S +         K+K          ++  S+ E  E+ +K KK K+++
Sbjct: 108 SSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDET 167

Query: 389 TSKYEVLTVQEPPRIEDAEEFPNLAVASERRDRIETPKFQSKQ--QPQDNFKNNVKKSQL 446
             + +V ++ +  +    ++ P  + +S   D  E  + + K+  + ++  K  VKK   
Sbjct: 168 EKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKK-- 225

Query: 447 PVQLDLGGMLTALEKKQHSQHAKQSSK 473
                        +KKQH +H+K+  K
Sbjct: 226 -------------KKKQHKKHSKKKKK 239


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 38.9 bits (89), Expect = 0.020
 Identities = 60/301 (19%), Positives = 119/301 (39%), Gaps = 16/301 (5%)

Query: 372 LEQNEASRKNKKKKEKSTSKYEVLTVQEPPRIEDAEEFPNLAVASERRDRIETPKFQSKQ 431
           L++ E  R+ + K+E+     + L  +E  R+E  E         E+R + E P+ + +Q
Sbjct: 579 LKREEERRQQRLKREQEERLEQRLKREEVERLEQEER-------REQRLKREEPEEERRQ 631

Query: 432 QPQDNFKNNVKKSQLPVQLDLGGMLTALEKKQHSQHAKQSSKPVVVSVGAVPVLSKECAS 491
           Q   + +   ++ Q   +         L++++  +  +Q  K           L++E   
Sbjct: 632 QLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQE 691

Query: 492 GERGRRMSQMKTPHNPLDSSAPLMKKGKQREIPKAKKPTSLKKIILKERQERKQRLQENA 551
             R R  S++      L+S A   ++ K    P+ ++    ++   ++R+ R+  LQ   
Sbjct: 692 QARERIKSRIPKWQWQLESEAD-ARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQE 750

Query: 552 VSPAFTSDDTQDGESGGDDQFPEQAELSGPEGMDELISTPSVEDKSEEPPGTELQRDTEA 611
              A      Q+ E   D  +  QAE     G   L + P + ++ E     E ++  E 
Sbjct: 751 EERAHRQQ--QEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQ 808

Query: 612 SHLAPNHTTFPKIHSRRFRDYCSQMLSKEVDACVTDLLKELVRFQDRMYQKDPVKAKTKR 671
             L        +   RR R+   Q L +E      + L+   R Q    ++D ++   +R
Sbjct: 809 RFLPEEEEKEQRRRQRREREKELQFLEEE------EQLQRRERAQQLQEEEDGLQEDQER 862

Query: 672 R 672
           R
Sbjct: 863 R 863



 Score = 32.3 bits (72), Expect = 1.9
 Identities = 38/204 (18%), Positives = 89/204 (43%), Gaps = 15/204 (7%)

Query: 351  YNKEKHIIHPTQKSKASQGSDLEQNEASRKNKKKKEKSTSKYEVLTVQEPPRIEDAE--- 407
            Y +E+ +    ++    +     + E  R+ ++++E    + ++L  ++  R ++ E   
Sbjct: 1140 YREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQY 1199

Query: 408  --EFPNLAVASERRDRIETPKFQSKQQPQDNFKNNVKKSQLPVQLDLGGMLTALEKKQHS 465
              E        ++R R E  +   K Q +   +N V+ +++  +         LE  Q  
Sbjct: 1200 REEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLR 1259

Query: 466  QHAKQSSKPVVVSVGAVPVLSKECASGERGRRMSQMKTPHNPLDSSAPLMKKGKQREIPK 525
               +QS + +   +G      ++    E+ RR  Q +  H P +     +++ +Q+E  +
Sbjct: 1260 D--RQSQQDLQHLLG-----EQQERDREQERRRWQQRDRHFPEEEQ---LEREEQKEAKR 1309

Query: 526  AKKPTSLKKIILKERQERKQRLQE 549
              + +  +K +L+E +E K+R QE
Sbjct: 1310 RDRKSQEEKQLLREEREEKRRRQE 1333


>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
           [Homo sapiens]
          Length = 914

 Score = 38.9 bits (89), Expect = 0.020
 Identities = 38/202 (18%), Positives = 83/202 (41%), Gaps = 19/202 (9%)

Query: 353 KEKHIIHPTQKSKASQGSDLEQNEASRKNKKKKEKSTSKYEVLTVQEPPRIEDAEEFPNL 412
           + + ++ PT   ++   S +++N   R + K+KE+         ++   R E+AE+    
Sbjct: 501 RNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQR-------LENLRRKEEAEQLRRQ 553

Query: 413 AVASERRDRIETPKFQSKQQPQDNFK--------NNVKKSQLPVQLDLGGMLTALEKKQH 464
            V  ++R R+E  K + +++ +   +           KK Q+  +       T   K++ 
Sbjct: 554 KVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEER 613

Query: 465 SQHAKQSSKPVVVSVGAVPVLSKECASGERGRRMSQMKTPHNPLDSSAPLMKKGKQREIP 524
               K   K     +  V    K+     R R + Q +      +    L++K K+ E  
Sbjct: 614 LAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQE----LLQKKKEEEQE 669

Query: 525 KAKKPTSLKKIILKERQERKQR 546
           + +K    K++  +  QER+++
Sbjct: 670 RLRKAAEAKRLAEQREQERREQ 691


>gi|154090979 hypothetical protein LOC57481 [Homo sapiens]
          Length = 1709

 Score = 38.5 bits (88), Expect = 0.027
 Identities = 45/182 (24%), Positives = 75/182 (41%), Gaps = 19/182 (10%)

Query: 252 ISLLREVVKPAAVLSKGEIVVKNNPNESVTANAATNSPSCTRELSWTPMGYVVRQTLSTE 311
           +S++  V++P       EI+ KN     V  +    SP   ++ +         Q+ S E
Sbjct: 313 LSIIPPVIQP-------EIISKN----LVEISLDDESPKNPQKKALPHKSLTATQSFS-E 360

Query: 312 LSAAPKNVTSMINLKTIASSAD---PKNVSIPSSEALSSDPSYNKEKHIIHPTQKSKASQ 368
           LS+ P    S+    T+AS++    P   S P++     D S  + K  ++P ++ K  Q
Sbjct: 361 LSSGPDCSQSLTAFATLASTSSTQLPIGFSTPATTQGCLDSSAARHKMTLNPRKQKKNLQ 420

Query: 369 ----GSDLEQNEASRKNKKKKEKSTSKYEVLTVQEPPRIEDAEEFPNLAVASERRDRIET 424
               G  +  +      +   +  T   E   + EP  +E  EE PNL + SE    I  
Sbjct: 421 VIIRGLPVWFSHFQGILEGSLQCVTQTLETPNLDEPLPVEPKEEEPNLPLVSEEEKSITK 480

Query: 425 PK 426
           PK
Sbjct: 481 PK 482



 Score = 31.6 bits (70), Expect = 3.3
 Identities = 48/214 (22%), Positives = 80/214 (37%), Gaps = 27/214 (12%)

Query: 330  SSADPKNVSIPSSEALSSDPSYNKEKHIIHPTQKSKASQGSDLEQN--------EASRKN 381
            SS  P NV +  S      PS +  +  +H +  + A++ S  E N        + +   
Sbjct: 1347 SSKGPVNVPVKQSSGEKHLPSSSPFQQQVHSSSVNAAARRSVFESNSDNWFLGRDEAFAI 1406

Query: 382  KKKKEKSTSKYEVLTVQEPPRIEDAEEFPNLAVASERRDRIETPKFQSKQQPQDNFKNNV 441
            K KK    SK  + ++  P     A +     +A  R+       +  K+  +    NN 
Sbjct: 1407 KTKKFSQGSKNPIKSIPAP-----ATKPGKFTIAPVRQTSTSGGIYSKKEDLESGDGNNN 1461

Query: 442  KKSQLPVQLDL----GGMLTALEKKQHSQHAKQSSKPVVVSVGAVPVLSKECASGERGRR 497
            + + L  Q D+    G  L      Q  +  KQ +   + SV + P+      S   GR 
Sbjct: 1462 QHANLSNQDDVEKLFGVRLKRAPPSQKYKSEKQDNFTQLASVPSGPI------SSSVGRG 1515

Query: 498  MSQMKTPHNPLDSSAPLMK----KGKQREIPKAK 527
                 T    LD++  L K      KQ+  PK++
Sbjct: 1516 HKIRSTSQGLLDAAGNLTKISYVADKQQSRPKSE 1549


>gi|134304846 Rb1-inducible coiled coil protein 1 isoform 2 [Homo
            sapiens]
          Length = 1591

 Score = 38.1 bits (87), Expect = 0.035
 Identities = 62/317 (19%), Positives = 128/317 (40%), Gaps = 34/317 (10%)

Query: 361  TQKSKASQGSDLEQNEASRKNKKKKEKSTSKYEV--LTVQEPPRIEDAEEFPNLAVASER 418
            T KS   Q ++  + E S+ N+K ++ + + Y+V    ++    IE  +    L    E 
Sbjct: 1088 TLKSLLEQETENLRTEISKLNQKIQDNNEN-YQVGLAELRTLMTIEKDQCISELISRHEE 1146

Query: 419  RDRI---ETPKFQSKQQPQDNFKNNVKKSQLPVQLDLGGMLTALEKKQHSQHAKQSSKPV 475
               I   E  K  S        + N+K+  + +Q  L   L+ALE+++  +  +Q  K  
Sbjct: 1147 ESNILKAELNKVTSLHNQAFEIEKNLKEQIIELQSKLDSELSALERQKDEKITQQEEKYE 1206

Query: 476  VVSVGAVPVLSKECASGERGRRMSQMKTPHNPLDSSAPLMKKGKQREIPKAKKPTSLKKI 535
             +         K  +S E+ R     K            +   K   I  A K   L++ 
Sbjct: 1207 AIIQNLEKDRQKLVSSQEQDREQLIQK------------LNCEKDEAIQTALKEFKLERE 1254

Query: 536  ILKERQERKQRLQENAVSPAFTSDDTQDGESGGDDQFPEQAELSGPEGMDELISTPSVED 595
            ++++    K +  EN ++ +   D T+   S    +  E+ +    + +++L        
Sbjct: 1255 VVEKELLEKVKHLENQIAKSPAIDSTRGDSSSLVAELQEKLQEEKAKFLEQL-------- 1306

Query: 596  KSEEPPGTELQRDTEASHLAPNHTTFPKIHSRRFRDYCSQMLSKEVDACVTDLLKELVRF 655
            + +E    E  ++   S +A   T F  + +R       +M  + +   ++D LK  ++ 
Sbjct: 1307 EEQEKRKNEEMQNVRTSLIAEQQTNFNTVLTR------EKMRKENIINDLSDKLKSTMQQ 1360

Query: 656  QDRMYQKDPVKAKTKRR 672
            Q+R   KD +++ ++ R
Sbjct: 1361 QER--DKDLIESLSEDR 1375


>gi|134304842 Rb1-inducible coiled coil protein 1 isoform 1 [Homo
            sapiens]
          Length = 1594

 Score = 38.1 bits (87), Expect = 0.035
 Identities = 62/317 (19%), Positives = 128/317 (40%), Gaps = 34/317 (10%)

Query: 361  TQKSKASQGSDLEQNEASRKNKKKKEKSTSKYEV--LTVQEPPRIEDAEEFPNLAVASER 418
            T KS   Q ++  + E S+ N+K ++ + + Y+V    ++    IE  +    L    E 
Sbjct: 1088 TLKSLLEQETENLRTEISKLNQKIQDNNEN-YQVGLAELRTLMTIEKDQCISELISRHEE 1146

Query: 419  RDRI---ETPKFQSKQQPQDNFKNNVKKSQLPVQLDLGGMLTALEKKQHSQHAKQSSKPV 475
               I   E  K  S        + N+K+  + +Q  L   L+ALE+++  +  +Q  K  
Sbjct: 1147 ESNILKAELNKVTSLHNQAFEIEKNLKEQIIELQSKLDSELSALERQKDEKITQQEEKYE 1206

Query: 476  VVSVGAVPVLSKECASGERGRRMSQMKTPHNPLDSSAPLMKKGKQREIPKAKKPTSLKKI 535
             +         K  +S E+ R     K            +   K   I  A K   L++ 
Sbjct: 1207 AIIQNLEKDRQKLVSSQEQDREQLIQK------------LNCEKDEAIQTALKEFKLERE 1254

Query: 536  ILKERQERKQRLQENAVSPAFTSDDTQDGESGGDDQFPEQAELSGPEGMDELISTPSVED 595
            ++++    K +  EN ++ +   D T+   S    +  E+ +    + +++L        
Sbjct: 1255 VVEKELLEKVKHLENQIAKSPAIDSTRGDSSSLVAELQEKLQEEKAKFLEQL-------- 1306

Query: 596  KSEEPPGTELQRDTEASHLAPNHTTFPKIHSRRFRDYCSQMLSKEVDACVTDLLKELVRF 655
            + +E    E  ++   S +A   T F  + +R       +M  + +   ++D LK  ++ 
Sbjct: 1307 EEQEKRKNEEMQNVRTSLIAEQQTNFNTVLTR------EKMRKENIINDLSDKLKSTMQQ 1360

Query: 656  QDRMYQKDPVKAKTKRR 672
            Q+R   KD +++ ++ R
Sbjct: 1361 QER--DKDLIESLSEDR 1375


>gi|219842214 protein phosphatase 1, regulatory (inhibitor) subunit
           12A isoform b [Homo sapiens]
          Length = 943

 Score = 37.7 bits (86), Expect = 0.046
 Identities = 85/462 (18%), Positives = 182/462 (39%), Gaps = 68/462 (14%)

Query: 259 VKPAAVLSKGEIVVKNNPNESVTANAATNSPSCTRELSWTPMGYVVRQTLSTELSAAPKN 318
           V  AA L K  +   +   +  T +++  + S T    W         +   E  + P  
Sbjct: 489 VTSAAGLQKSLLSSTSTTTKITTGSSSAGTQSSTSNRLWA------EDSTEKEKDSVPTA 542

Query: 319 VTSMINLKTIASSADPKNVSIPSSEALSSDPSYNKEKHIIHPTQKSKASQGSDLEQNEAS 378
           VT  +    + ++A    ++  ++  +SS     + +       + + S+     Q +A 
Sbjct: 543 VTIPVAPTVVNAAASTTTLTTTTAGTVSSTTEVRERRRSYLTPVRDEESES----QRKAR 598

Query: 379 RKNKKKKEKSTSKYEVLTVQEPPRIEDAEEFPNLAVASERRDRIETPKFQSKQQPQDNFK 438
            +  ++  +ST    +  +QE      AE+    + ++  R++    K + +++ QD  K
Sbjct: 599 SRQARQSRRSTQGVTLTDLQE------AEKTIGRSRSTRTREQENEEKEKEEKEKQDKEK 652

Query: 439 NNVKKSQLPVQLDLGGMLTALEKKQHSQ---HAKQSSKPVVVSVGAVPVLSKECASGERG 495
              KK     + D         K+++S+      Q  +PV  S    P  S    S    
Sbjct: 653 QEEKKESETSREDE-------YKQKYSRTYDETYQRYRPVSTSSSTTPSSSLSTMSSSL- 704

Query: 496 RRMSQMKTPHNPLDSSAPLMK--------KGKQREIPKAKKPTSLKKIILKERQERKQR- 546
              SQ+  P++ +  ++   +        +G++RE  K  +  S  K I + R+ R++R 
Sbjct: 705 YASSQLNRPNSLVGITSAYSRGITKENEREGEKREEEKEGEDKSQPKSIRERRRPREKRR 764

Query: 547 -------LQENAVSPAFTSDDTQDGESGGDDQFP-----EQAELSGPEGMDELISTPSVE 594
                   Q++  +      DT++G +  + Q       E +  S  +  D L+      
Sbjct: 765 STGVSFWTQDSDENEQEQQSDTEEGSNKKETQTDSISRYETSSTSAGDRYDSLLGRSGSY 824

Query: 595 DKSEE--PPGTELQRDTEASHLAPNHTTFPKIHSRRFRDYCSQMLSKEV---DACVTDL- 648
              EE  P  + L++D        + T F K++ +   +  ++ L  ++   +  +TDL 
Sbjct: 825 SYLEERKPYSSRLEKD--------DSTDFKKLYEQILAE--NEKLKAQLHDTNMELTDLK 874

Query: 649 --LKELVRFQDRMYQKDPVKAKTKRRLVLGLR--EVLKHLKL 686
             L++  + Q+R   +  ++ + + R  L  R  E+ + LK+
Sbjct: 875 LQLEKATQRQERFADRSLLEMEKRERRALERRISEMEEELKM 916


>gi|219842212 protein phosphatase 1, regulatory (inhibitor) subunit
            12A isoform a [Homo sapiens]
          Length = 1030

 Score = 37.7 bits (86), Expect = 0.046
 Identities = 85/462 (18%), Positives = 182/462 (39%), Gaps = 68/462 (14%)

Query: 259  VKPAAVLSKGEIVVKNNPNESVTANAATNSPSCTRELSWTPMGYVVRQTLSTELSAAPKN 318
            V  AA L K  +   +   +  T +++  + S T    W         +   E  + P  
Sbjct: 576  VTSAAGLQKSLLSSTSTTTKITTGSSSAGTQSSTSNRLWA------EDSTEKEKDSVPTA 629

Query: 319  VTSMINLKTIASSADPKNVSIPSSEALSSDPSYNKEKHIIHPTQKSKASQGSDLEQNEAS 378
            VT  +    + ++A    ++  ++  +SS     + +       + + S+     Q +A 
Sbjct: 630  VTIPVAPTVVNAAASTTTLTTTTAGTVSSTTEVRERRRSYLTPVRDEESES----QRKAR 685

Query: 379  RKNKKKKEKSTSKYEVLTVQEPPRIEDAEEFPNLAVASERRDRIETPKFQSKQQPQDNFK 438
             +  ++  +ST    +  +QE      AE+    + ++  R++    K + +++ QD  K
Sbjct: 686  SRQARQSRRSTQGVTLTDLQE------AEKTIGRSRSTRTREQENEEKEKEEKEKQDKEK 739

Query: 439  NNVKKSQLPVQLDLGGMLTALEKKQHSQ---HAKQSSKPVVVSVGAVPVLSKECASGERG 495
               KK     + D         K+++S+      Q  +PV  S    P  S    S    
Sbjct: 740  QEEKKESETSREDE-------YKQKYSRTYDETYQRYRPVSTSSSTTPSSSLSTMSSSL- 791

Query: 496  RRMSQMKTPHNPLDSSAPLMK--------KGKQREIPKAKKPTSLKKIILKERQERKQR- 546
               SQ+  P++ +  ++   +        +G++RE  K  +  S  K I + R+ R++R 
Sbjct: 792  YASSQLNRPNSLVGITSAYSRGITKENEREGEKREEEKEGEDKSQPKSIRERRRPREKRR 851

Query: 547  -------LQENAVSPAFTSDDTQDGESGGDDQFP-----EQAELSGPEGMDELISTPSVE 594
                    Q++  +      DT++G +  + Q       E +  S  +  D L+      
Sbjct: 852  STGVSFWTQDSDENEQEQQSDTEEGSNKKETQTDSISRYETSSTSAGDRYDSLLGRSGSY 911

Query: 595  DKSEE--PPGTELQRDTEASHLAPNHTTFPKIHSRRFRDYCSQMLSKEV---DACVTDL- 648
               EE  P  + L++D        + T F K++ +   +  ++ L  ++   +  +TDL 
Sbjct: 912  SYLEERKPYSSRLEKD--------DSTDFKKLYEQILAE--NEKLKAQLHDTNMELTDLK 961

Query: 649  --LKELVRFQDRMYQKDPVKAKTKRRLVLGLR--EVLKHLKL 686
              L++  + Q+R   +  ++ + + R  L  R  E+ + LK+
Sbjct: 962  LQLEKATQRQERFADRSLLEMEKRERRALERRISEMEEELKM 1003


>gi|4505317 protein phosphatase 1, regulatory (inhibitor) subunit 12A
            isoform a [Homo sapiens]
          Length = 1030

 Score = 37.7 bits (86), Expect = 0.046
 Identities = 85/462 (18%), Positives = 182/462 (39%), Gaps = 68/462 (14%)

Query: 259  VKPAAVLSKGEIVVKNNPNESVTANAATNSPSCTRELSWTPMGYVVRQTLSTELSAAPKN 318
            V  AA L K  +   +   +  T +++  + S T    W         +   E  + P  
Sbjct: 576  VTSAAGLQKSLLSSTSTTTKITTGSSSAGTQSSTSNRLWA------EDSTEKEKDSVPTA 629

Query: 319  VTSMINLKTIASSADPKNVSIPSSEALSSDPSYNKEKHIIHPTQKSKASQGSDLEQNEAS 378
            VT  +    + ++A    ++  ++  +SS     + +       + + S+     Q +A 
Sbjct: 630  VTIPVAPTVVNAAASTTTLTTTTAGTVSSTTEVRERRRSYLTPVRDEESES----QRKAR 685

Query: 379  RKNKKKKEKSTSKYEVLTVQEPPRIEDAEEFPNLAVASERRDRIETPKFQSKQQPQDNFK 438
             +  ++  +ST    +  +QE      AE+    + ++  R++    K + +++ QD  K
Sbjct: 686  SRQARQSRRSTQGVTLTDLQE------AEKTIGRSRSTRTREQENEEKEKEEKEKQDKEK 739

Query: 439  NNVKKSQLPVQLDLGGMLTALEKKQHSQ---HAKQSSKPVVVSVGAVPVLSKECASGERG 495
               KK     + D         K+++S+      Q  +PV  S    P  S    S    
Sbjct: 740  QEEKKESETSREDE-------YKQKYSRTYDETYQRYRPVSTSSSTTPSSSLSTMSSSL- 791

Query: 496  RRMSQMKTPHNPLDSSAPLMK--------KGKQREIPKAKKPTSLKKIILKERQERKQR- 546
               SQ+  P++ +  ++   +        +G++RE  K  +  S  K I + R+ R++R 
Sbjct: 792  YASSQLNRPNSLVGITSAYSRGITKENEREGEKREEEKEGEDKSQPKSIRERRRPREKRR 851

Query: 547  -------LQENAVSPAFTSDDTQDGESGGDDQFP-----EQAELSGPEGMDELISTPSVE 594
                    Q++  +      DT++G +  + Q       E +  S  +  D L+      
Sbjct: 852  STGVSFWTQDSDENEQEQQSDTEEGSNKKETQTDSISRYETSSTSAGDRYDSLLGRSGSY 911

Query: 595  DKSEE--PPGTELQRDTEASHLAPNHTTFPKIHSRRFRDYCSQMLSKEV---DACVTDL- 648
               EE  P  + L++D        + T F K++ +   +  ++ L  ++   +  +TDL 
Sbjct: 912  SYLEERKPYSSRLEKD--------DSTDFKKLYEQILAE--NEKLKAQLHDTNMELTDLK 961

Query: 649  --LKELVRFQDRMYQKDPVKAKTKRRLVLGLR--EVLKHLKL 686
              L++  + Q+R   +  ++ + + R  L  R  E+ + LK+
Sbjct: 962  LQLEKATQRQERFADRSLLEMEKRERRALERRISEMEEELKM 1003


>gi|40068059 CBF1 interacting corepressor [Homo sapiens]
          Length = 450

 Score = 37.4 bits (85), Expect = 0.060
 Identities = 25/77 (32%), Positives = 38/77 (49%), Gaps = 3/77 (3%)

Query: 329 ASSADPKNVSIPSSEALSSDPSYNKEKHIIHPTQKSKASQGSDLEQNEASRKNKKKK--- 385
           +SS+   + S  +SE+ S   S NKEK I    +K     G +   +E   K+KK+K   
Sbjct: 261 SSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHE 320

Query: 386 EKSTSKYEVLTVQEPPR 402
           E S+S +     +E PR
Sbjct: 321 ELSSSHHNREKAKEKPR 337


>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
          Length = 1976

 Score = 37.0 bits (84), Expect = 0.078
 Identities = 34/146 (23%), Positives = 67/146 (45%), Gaps = 11/146 (7%)

Query: 362  QKSKASQGSDLEQNEASRKNKKKKEKSTSKYEVLTVQEPPRIEDAEEFPNLAVASERRDR 421
            Q  KA    DL+  +   +N++KK     +   L  +    +ED  +   LAVAS+++  
Sbjct: 1570 QAMKAQFERDLQTRD--EQNEEKKRLLIKQVRELEAE----LEDERKQRALAVASKKKME 1623

Query: 422  IETPKFQSKQQPQDNFKNNVKKSQLPVQLDLGGMLTALEKKQHSQ-----HAKQSSKPVV 476
            I+    +++ +  +  ++ V K    +Q  +      LE+ + S+      +K+S K + 
Sbjct: 1624 IDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLK 1683

Query: 477  VSVGAVPVLSKECASGERGRRMSQMK 502
                 +  L +E AS ER RR ++ +
Sbjct: 1684 SLEAEILQLQEELASSERARRHAEQE 1709



 Score = 32.0 bits (71), Expect = 2.5
 Identities = 47/226 (20%), Positives = 85/226 (37%), Gaps = 34/226 (15%)

Query: 352  NKEKHIIHPTQKSKASQGSDLEQNEASRKNKKKKEKSTSK------------YEVLTVQE 399
            N    ++   Q   A    D E  +ASR   +K+++  S+             +    Q+
Sbjct: 1107 NNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQ 1166

Query: 400  PPRIEDAEEFPNLAVASERRDRIETPKFQSKQQ--------------PQDNFKNNVKKSQ 445
              R +  +E   L  A E   +    + Q  +Q                  FK N++K++
Sbjct: 1167 ELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNK 1226

Query: 446  LPVQLDLGGMLTALEKKQHSQHAKQSSKPVVVSVGAVPVLSKECASGERGRRMSQMKTP- 504
              ++ D      A E K   Q   +S          V  L  + + G+R R     K   
Sbjct: 1227 QGLETD--NKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASK 1284

Query: 505  -HNPLDSSAPLMKKGKQREIPKAKKPTSLKKIILKERQERKQRLQE 549
              N LD+ + L+++ +++ I  AK   SL+     + Q+ ++ LQE
Sbjct: 1285 LQNELDNVSTLLEEAEKKGIKFAKDAASLE----SQLQDTQELLQE 1326


>gi|4758876 poly(A) binding protein, nuclear 1 [Homo sapiens]
          Length = 306

 Score = 36.6 bits (83), Expect = 0.10
 Identities = 24/63 (38%), Positives = 30/63 (47%), Gaps = 10/63 (15%)

Query: 788 PRPQAPPSLPTQGPSCPAEDGPPALKEKEEPHYIE-------IWKKHLEAYSGCTLELEE 840
           PRP+APP  P  GP   A   P + +E+EEP  +E       I    LEA      E+EE
Sbjct: 75  PRPRAPPGAPGPGPGSGA---PGSQEEEEEPGLVEGDPGDGAIEDPELEAIKARVREMEE 131

Query: 841 SLE 843
             E
Sbjct: 132 EAE 134


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.127    0.358 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,364,610
Number of Sequences: 37866
Number of extensions: 1652906
Number of successful extensions: 7940
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 42
Number of HSP's successfully gapped in prelim test: 228
Number of HSP's that attempted gapping in prelim test: 7525
Number of HSP's gapped (non-prelim): 679
length of query: 854
length of database: 18,247,518
effective HSP length: 111
effective length of query: 743
effective length of database: 14,044,392
effective search space: 10434983256
effective search space used: 10434983256
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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