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Search of human proteins with 83267879
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|83267879 eukaryotic translation initiation factor 2B,
subunit 5 epsilon, 82kDa [Homo sapiens]
(721 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|83267879 eukaryotic translation initiation factor 2B, subunit... 1442 0.0
gi|7661744 basic leucine zipper and W2 domains 2 [Homo sapiens] 54 5e-07
gi|229577398 basic leucine zipper and W2 domains 2 [Homo sapiens] 54 5e-07
gi|38201621 eukaryotic translation initiation factor 4 gamma, 1 ... 53 9e-07
gi|38201627 eukaryotic translation initiation factor 4 gamma, 1 ... 53 9e-07
gi|38201625 eukaryotic translation initiation factor 4 gamma, 1 ... 53 9e-07
gi|38201623 eukaryotic translation initiation factor 4 gamma, 1 ... 53 9e-07
gi|38201619 eukaryotic translation initiation factor 4 gamma, 1 ... 53 9e-07
gi|9966779 eukaryotic translation initiation factor 2B, subunit ... 52 3e-06
gi|41281429 basic leucine zipper and W2 domains 1 [Homo sapiens] 49 1e-05
gi|21361337 eukaryotic translation initiation factor 5 [Homo sap... 45 2e-04
gi|37537716 eukaryotic translation initiation factor 5 [Homo sap... 45 2e-04
gi|110630018 eukaryotic translation initiation factor 4 gamma, 2... 45 3e-04
gi|4503539 eukaryotic translation initiation factor 4 gamma, 2 i... 45 3e-04
gi|4504487 histidine rich calcium binding protein precursor [Hom... 43 0.001
gi|10092601 eukaryotic translation initiation factor 4 gamma, 3 ... 40 0.006
gi|24415404 MDN1, midasin homolog [Homo sapiens] 39 0.013
gi|11761619 GDP-mannose pyrophosphorylase B isoform 1 [Homo sapi... 39 0.022
gi|55769548 PHD finger protein 14 isoform 2 [Homo sapiens] 37 0.049
gi|55769550 PHD finger protein 14 isoform 1 [Homo sapiens] 37 0.049
gi|157674363 protein phosphatase 1, regulatory subunit 15A [Homo... 37 0.084
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 37 0.084
gi|55749531 splicing factor 3B subunit 2 [Homo sapiens] 37 0.084
gi|154355000 KH-type splicing regulatory protein [Homo sapiens] 36 0.14
gi|76150625 nucleolar protein 1, 120kDa [Homo sapiens] 35 0.19
gi|76150623 nucleolar protein 1, 120kDa [Homo sapiens] 35 0.19
gi|55956788 nucleolin [Homo sapiens] 35 0.24
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 35 0.24
gi|194248068 synaptic Ras GTPase activating protein 1 [Homo sapi... 35 0.24
gi|78486540 DDB1 and CUL4 associated factor 15 [Homo sapiens] 35 0.32
>gi|83267879 eukaryotic translation initiation factor 2B, subunit 5
epsilon, 82kDa [Homo sapiens]
Length = 721
Score = 1442 bits (3734), Expect = 0.0
Identities = 721/721 (100%), Positives = 721/721 (100%)
Query: 1 MAAPVVAPPGVVVSRANKRSGAGPGGSGGGGARGAEEEPPPPLQAVLVADSFDRRFFPIS 60
MAAPVVAPPGVVVSRANKRSGAGPGGSGGGGARGAEEEPPPPLQAVLVADSFDRRFFPIS
Sbjct: 1 MAAPVVAPPGVVVSRANKRSGAGPGGSGGGGARGAEEEPPPPLQAVLVADSFDRRFFPIS 60
Query: 61 KDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQIKEHLLKSKWCRPTSLNVV 120
KDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQIKEHLLKSKWCRPTSLNVV
Sbjct: 61 KDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQIKEHLLKSKWCRPTSLNVV 120
Query: 121 RIITSELYRSLGDVLRDVDAKALVRSDFLLVYGDVISNINITRALEEHRLRRKLEKNVSV 180
RIITSELYRSLGDVLRDVDAKALVRSDFLLVYGDVISNINITRALEEHRLRRKLEKNVSV
Sbjct: 121 RIITSELYRSLGDVLRDVDAKALVRSDFLLVYGDVISNINITRALEEHRLRRKLEKNVSV 180
Query: 181 MTMIFKESSPSHPTRCHEDNVVVAVDSTTNRVLHFQKTQGLRRFAFPLSLFQGSSDGVEV 240
MTMIFKESSPSHPTRCHEDNVVVAVDSTTNRVLHFQKTQGLRRFAFPLSLFQGSSDGVEV
Sbjct: 181 MTMIFKESSPSHPTRCHEDNVVVAVDSTTNRVLHFQKTQGLRRFAFPLSLFQGSSDGVEV 240
Query: 241 RYDLLDCHISICSPQVAQLFTDNFDYQTRDDFVRGLLVNEEILGNQIHMHVTAKEYGARV 300
RYDLLDCHISICSPQVAQLFTDNFDYQTRDDFVRGLLVNEEILGNQIHMHVTAKEYGARV
Sbjct: 241 RYDLLDCHISICSPQVAQLFTDNFDYQTRDDFVRGLLVNEEILGNQIHMHVTAKEYGARV 300
Query: 301 SNLHMYSAVCADVIRRWVYPLTPEANFTDSTTQSCTHSRHNIYRGPEVSLGHGSILEENV 360
SNLHMYSAVCADVIRRWVYPLTPEANFTDSTTQSCTHSRHNIYRGPEVSLGHGSILEENV
Sbjct: 301 SNLHMYSAVCADVIRRWVYPLTPEANFTDSTTQSCTHSRHNIYRGPEVSLGHGSILEENV 360
Query: 361 LLGSGTVIGSNCFITNSVIGPGCHIGDNVVLDQTYLWQGVRVAAGAQIHQSLLCDNAEVK 420
LLGSGTVIGSNCFITNSVIGPGCHIGDNVVLDQTYLWQGVRVAAGAQIHQSLLCDNAEVK
Sbjct: 361 LLGSGTVIGSNCFITNSVIGPGCHIGDNVVLDQTYLWQGVRVAAGAQIHQSLLCDNAEVK 420
Query: 421 ERVTLKPRSVLTSQVVVGPNITLPEGSVISLHPPDAEEDEDDGEFSDDSGADQEKDKVKM 480
ERVTLKPRSVLTSQVVVGPNITLPEGSVISLHPPDAEEDEDDGEFSDDSGADQEKDKVKM
Sbjct: 421 ERVTLKPRSVLTSQVVVGPNITLPEGSVISLHPPDAEEDEDDGEFSDDSGADQEKDKVKM 480
Query: 481 KGYNPAEVGAAGKGYLWKAAGMNMEEEEELQQNLWGLKINMEEESESESEQSMDSEEPDS 540
KGYNPAEVGAAGKGYLWKAAGMNMEEEEELQQNLWGLKINMEEESESESEQSMDSEEPDS
Sbjct: 481 KGYNPAEVGAAGKGYLWKAAGMNMEEEEELQQNLWGLKINMEEESESESEQSMDSEEPDS 540
Query: 541 RGGSPQMDDIKVFQNEVLGTLQRGKEENISCDNLVLEINSLKYAYNISLKEVMQVLSHVV 600
RGGSPQMDDIKVFQNEVLGTLQRGKEENISCDNLVLEINSLKYAYNISLKEVMQVLSHVV
Sbjct: 541 RGGSPQMDDIKVFQNEVLGTLQRGKEENISCDNLVLEINSLKYAYNISLKEVMQVLSHVV 600
Query: 601 LEFPLQQMDSPLDSSRYCALLLPLLKAWSPVFRNYIKRAADHLEALAAIEDFFLEHEALG 660
LEFPLQQMDSPLDSSRYCALLLPLLKAWSPVFRNYIKRAADHLEALAAIEDFFLEHEALG
Sbjct: 601 LEFPLQQMDSPLDSSRYCALLLPLLKAWSPVFRNYIKRAADHLEALAAIEDFFLEHEALG 660
Query: 661 ISMAKVLMAFYQLEILAEETILSWFSQRDTTDKGQQLRKNQQLQRFIQWLKEAEEESSED 720
ISMAKVLMAFYQLEILAEETILSWFSQRDTTDKGQQLRKNQQLQRFIQWLKEAEEESSED
Sbjct: 661 ISMAKVLMAFYQLEILAEETILSWFSQRDTTDKGQQLRKNQQLQRFIQWLKEAEEESSED 720
Query: 721 D 721
D
Sbjct: 721 D 721
>gi|7661744 basic leucine zipper and W2 domains 2 [Homo sapiens]
Length = 419
Score = 53.9 bits (128), Expect = 5e-07
Identities = 25/96 (26%), Positives = 56/96 (58%), Gaps = 2/96 (2%)
Query: 625 LKAWSPVFRNYIKRAADHLEALAAIEDFFLEHEALGISMAKVLMAFYQLEILAEETILSW 684
LK ++P+ + + L L ++++ ++ + K+++ FY+ ++L+EE IL W
Sbjct: 322 LKQYAPLLAVFSSQGQSELILLQKVQEYCYDNIHFMKAFQKIVVLFYKADVLSEEAILKW 381
Query: 685 FSQRDTTDKGQQLRKNQQLQRFIQWLKEAEEESSED 720
+ + KG+ + + Q+++F++WL+ AEEES +
Sbjct: 382 YKEAHVA-KGKSVFLD-QMKKFVEWLQNAEEESESE 415
>gi|229577398 basic leucine zipper and W2 domains 2 [Homo sapiens]
Length = 419
Score = 53.9 bits (128), Expect = 5e-07
Identities = 25/96 (26%), Positives = 56/96 (58%), Gaps = 2/96 (2%)
Query: 625 LKAWSPVFRNYIKRAADHLEALAAIEDFFLEHEALGISMAKVLMAFYQLEILAEETILSW 684
LK ++P+ + + L L ++++ ++ + K+++ FY+ ++L+EE IL W
Sbjct: 322 LKQYAPLLAVFSSQGQSELILLQKVQEYCYDNIHFMKAFQKIVVLFYKADVLSEEAILKW 381
Query: 685 FSQRDTTDKGQQLRKNQQLQRFIQWLKEAEEESSED 720
+ + KG+ + + Q+++F++WL+ AEEES +
Sbjct: 382 YKEAHVA-KGKSVFLD-QMKKFVEWLQNAEEESESE 415
>gi|38201621 eukaryotic translation initiation factor 4 gamma, 1
isoform 1 [Homo sapiens]
Length = 1599
Score = 53.1 bits (126), Expect = 9e-07
Identities = 49/241 (20%), Positives = 103/241 (42%), Gaps = 36/241 (14%)
Query: 488 VGAAGKGYLWKAAGMNMEEEEELQQNLWG------LKINMEEESESESEQSMDSEEPDSR 541
+G G LW+ AG++ +E Q++ ++ + EESE+ ++++ SEE
Sbjct: 1387 MGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEE---- 1442
Query: 542 GGSPQMDDIKVFQNEVLGTLQRGKEENISCDNLVLEINSLKYAYNISLKEVMQVL--SHV 599
++ L+ G D + ++ + N ++ +M + S +
Sbjct: 1443 -----------LNRQLEKLLKEGSSNQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAI 1491
Query: 600 VLEFPLQQMDSPLDSSRYCALLLPLLKAWSPVFRNYIKRAADHLEALAAIEDFFLEHEAL 659
+ E PL+ + + +LKA + + + Y+ L+AL A++ + E
Sbjct: 1492 IFETPLR-------------VDVAVLKARAKLLQKYLCDEQKELQALYALQALVVTLEQP 1538
Query: 660 GISMAKVLMAFYQLEILAEETILSWFSQRDTTDKGQQLRKNQQLQRFIQWLKEAEEESSE 719
+ A Y +++ E+ SW S +D ++ + + + F +WL+EAEEES
Sbjct: 1539 PNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDH 1598
Query: 720 D 720
+
Sbjct: 1599 N 1599
>gi|38201627 eukaryotic translation initiation factor 4 gamma, 1
isoform 2 [Homo sapiens]
Length = 1512
Score = 53.1 bits (126), Expect = 9e-07
Identities = 49/241 (20%), Positives = 103/241 (42%), Gaps = 36/241 (14%)
Query: 488 VGAAGKGYLWKAAGMNMEEEEELQQNLWG------LKINMEEESESESEQSMDSEEPDSR 541
+G G LW+ AG++ +E Q++ ++ + EESE+ ++++ SEE
Sbjct: 1300 MGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEE---- 1355
Query: 542 GGSPQMDDIKVFQNEVLGTLQRGKEENISCDNLVLEINSLKYAYNISLKEVMQVL--SHV 599
++ L+ G D + ++ + N ++ +M + S +
Sbjct: 1356 -----------LNRQLEKLLKEGSSNQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAI 1404
Query: 600 VLEFPLQQMDSPLDSSRYCALLLPLLKAWSPVFRNYIKRAADHLEALAAIEDFFLEHEAL 659
+ E PL+ + + +LKA + + + Y+ L+AL A++ + E
Sbjct: 1405 IFETPLR-------------VDVAVLKARAKLLQKYLCDEQKELQALYALQALVVTLEQP 1451
Query: 660 GISMAKVLMAFYQLEILAEETILSWFSQRDTTDKGQQLRKNQQLQRFIQWLKEAEEESSE 719
+ A Y +++ E+ SW S +D ++ + + + F +WL+EAEEES
Sbjct: 1452 PNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDH 1511
Query: 720 D 720
+
Sbjct: 1512 N 1512
>gi|38201625 eukaryotic translation initiation factor 4 gamma, 1
isoform 3 [Homo sapiens]
Length = 1435
Score = 53.1 bits (126), Expect = 9e-07
Identities = 49/241 (20%), Positives = 103/241 (42%), Gaps = 36/241 (14%)
Query: 488 VGAAGKGYLWKAAGMNMEEEEELQQNLWG------LKINMEEESESESEQSMDSEEPDSR 541
+G G LW+ AG++ +E Q++ ++ + EESE+ ++++ SEE
Sbjct: 1223 MGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEE---- 1278
Query: 542 GGSPQMDDIKVFQNEVLGTLQRGKEENISCDNLVLEINSLKYAYNISLKEVMQVL--SHV 599
++ L+ G D + ++ + N ++ +M + S +
Sbjct: 1279 -----------LNRQLEKLLKEGSSNQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAI 1327
Query: 600 VLEFPLQQMDSPLDSSRYCALLLPLLKAWSPVFRNYIKRAADHLEALAAIEDFFLEHEAL 659
+ E PL+ + + +LKA + + + Y+ L+AL A++ + E
Sbjct: 1328 IFETPLR-------------VDVAVLKARAKLLQKYLCDEQKELQALYALQALVVTLEQP 1374
Query: 660 GISMAKVLMAFYQLEILAEETILSWFSQRDTTDKGQQLRKNQQLQRFIQWLKEAEEESSE 719
+ A Y +++ E+ SW S +D ++ + + + F +WL+EAEEES
Sbjct: 1375 PNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDH 1434
Query: 720 D 720
+
Sbjct: 1435 N 1435
>gi|38201623 eukaryotic translation initiation factor 4 gamma, 1
isoform 1 [Homo sapiens]
Length = 1599
Score = 53.1 bits (126), Expect = 9e-07
Identities = 49/241 (20%), Positives = 103/241 (42%), Gaps = 36/241 (14%)
Query: 488 VGAAGKGYLWKAAGMNMEEEEELQQNLWG------LKINMEEESESESEQSMDSEEPDSR 541
+G G LW+ AG++ +E Q++ ++ + EESE+ ++++ SEE
Sbjct: 1387 MGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEE---- 1442
Query: 542 GGSPQMDDIKVFQNEVLGTLQRGKEENISCDNLVLEINSLKYAYNISLKEVMQVL--SHV 599
++ L+ G D + ++ + N ++ +M + S +
Sbjct: 1443 -----------LNRQLEKLLKEGSSNQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAI 1491
Query: 600 VLEFPLQQMDSPLDSSRYCALLLPLLKAWSPVFRNYIKRAADHLEALAAIEDFFLEHEAL 659
+ E PL+ + + +LKA + + + Y+ L+AL A++ + E
Sbjct: 1492 IFETPLR-------------VDVAVLKARAKLLQKYLCDEQKELQALYALQALVVTLEQP 1538
Query: 660 GISMAKVLMAFYQLEILAEETILSWFSQRDTTDKGQQLRKNQQLQRFIQWLKEAEEESSE 719
+ A Y +++ E+ SW S +D ++ + + + F +WL+EAEEES
Sbjct: 1539 PNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDH 1598
Query: 720 D 720
+
Sbjct: 1599 N 1599
>gi|38201619 eukaryotic translation initiation factor 4 gamma, 1
isoform 4 [Homo sapiens]
Length = 1403
Score = 53.1 bits (126), Expect = 9e-07
Identities = 49/241 (20%), Positives = 103/241 (42%), Gaps = 36/241 (14%)
Query: 488 VGAAGKGYLWKAAGMNMEEEEELQQNLWG------LKINMEEESESESEQSMDSEEPDSR 541
+G G LW+ AG++ +E Q++ ++ + EESE+ ++++ SEE
Sbjct: 1191 MGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEE---- 1246
Query: 542 GGSPQMDDIKVFQNEVLGTLQRGKEENISCDNLVLEINSLKYAYNISLKEVMQVL--SHV 599
++ L+ G D + ++ + N ++ +M + S +
Sbjct: 1247 -----------LNRQLEKLLKEGSSNQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAI 1295
Query: 600 VLEFPLQQMDSPLDSSRYCALLLPLLKAWSPVFRNYIKRAADHLEALAAIEDFFLEHEAL 659
+ E PL+ + + +LKA + + + Y+ L+AL A++ + E
Sbjct: 1296 IFETPLR-------------VDVAVLKARAKLLQKYLCDEQKELQALYALQALVVTLEQP 1342
Query: 660 GISMAKVLMAFYQLEILAEETILSWFSQRDTTDKGQQLRKNQQLQRFIQWLKEAEEESSE 719
+ A Y +++ E+ SW S +D ++ + + + F +WL+EAEEES
Sbjct: 1343 PNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDH 1402
Query: 720 D 720
+
Sbjct: 1403 N 1403
>gi|9966779 eukaryotic translation initiation factor 2B, subunit 3
gamma [Homo sapiens]
Length = 452
Score = 51.6 bits (122), Expect = 3e-06
Identities = 93/433 (21%), Positives = 159/433 (36%), Gaps = 64/433 (14%)
Query: 44 QAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCC--WKAAQ 101
QAV++A R ++ P+ LLP+ N LI Y L L G +E V + A
Sbjct: 4 QAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDVQKAL 63
Query: 102 IKEHLLKSKWCRPTSLNVVRIITSELYRSLGDVLRDVDAKALVRSDFLLVYGDVISNINI 161
E +K K + I + D LR + K +++D L++ D+I+++ +
Sbjct: 64 CAEFKMKMK-------PDIVCIPDDADMGTADSLRYIYPK--LKTDVLVLSCDLITDVAL 114
Query: 162 TRALEEHRLRRKLEKNVSVMTMIFKESSPSHP-----TRCHEDNVVVAVDSTTNRVLHFQ 216
++ L R + +++++ ++S P + E + VDST R+L
Sbjct: 115 HEVVD---LFRAYDASLAMLMRKGQDSIEPVPGQKGKKKAVEQRDFIGVDSTGKRLLFMA 171
Query: 217 KTQGLRRFAFPLSLFQGSSDGVEVRYDLLDCHISICSPQVAQLFTDN----------FDY 266
L + L+D H+ + +N Y
Sbjct: 172 NEADLDEELVIKGSILQKHPRIRFHTGLVDAHLYCLKKYIVDFLMENGSITSIRSELIPY 231
Query: 267 QTRDDF-----VRGLLVNEEILGNQ----IHMHVTAKEYGARVSNLHMYSA--------- 308
R F +G EE L + + ++ KE A NL Y A
Sbjct: 232 LVRKQFSSASSQQGQEEKEEDLKKKELKSLDIYSFIKE--ANTLNLAPYDACWNACRGDR 289
Query: 309 ---VCADVIRRWVYPLTPEANFTDSTTQSCTHSRHNIYR-----GPEVSLGHGS------ 354
+ +R +V+ + ST + + + PE H S
Sbjct: 290 WEDLSRSQVRCYVHIMKEGLCSRVSTLGLYMEANRQVPKLLSALCPEEPPVHSSAQIVSK 349
Query: 355 -ILEENVLLGSGTVIGSNCFITNSVIGPGCHIGDNVVLDQTYLWQGVRVAAGAQIHQSLL 413
++ + L+G T IG I SVIG C I D V + L V V G+ I S++
Sbjct: 350 HLVGVDSLIGPETQIGEKSSIKRSVIGSSCLIKDRVTITNCLLMNSVTVEEGSNIQGSVI 409
Query: 414 CDNAEVKERVTLK 426
C+NA +++ +K
Sbjct: 410 CNNAVIEKGADIK 422
>gi|41281429 basic leucine zipper and W2 domains 1 [Homo sapiens]
Length = 353
Score = 49.3 bits (116), Expect = 1e-05
Identities = 22/56 (39%), Positives = 38/56 (67%), Gaps = 2/56 (3%)
Query: 665 KVLMAFYQLEILAEETILSWFSQRDTTDKGQQLRKNQQLQRFIQWLKEAEEESSED 720
K+++ FY+ E+L+EE IL W+ KG+ + +Q+++F++WLK AEEES +
Sbjct: 295 KIVVLFYKAEVLSEEPILKWYKDAHVA-KGKSVFL-EQMKKFVEWLKNAEEESESE 348
>gi|21361337 eukaryotic translation initiation factor 5 [Homo
sapiens]
Length = 431
Score = 45.1 bits (105), Expect = 2e-04
Identities = 31/85 (36%), Positives = 47/85 (55%), Gaps = 5/85 (5%)
Query: 637 KRAADHLEALAAIEDFFLEHEALGIS-MAKVLMAFYQLEILAEETILSWFSQRDTTDKGQ 695
K+A +L L +E H+A IS + +L Y ++L EE I+SW + +
Sbjct: 308 KKAQRYL--LHGLECVVAMHQAQLISKIPHILKEMYDADLLEEEVIISWSEKASKKYVSK 365
Query: 696 QLRKNQQLQR--FIQWLKEAEEESS 718
+L K +++ FI+WLKEAEEESS
Sbjct: 366 ELAKEIRVKAEPFIKWLKEAEEESS 390
>gi|37537716 eukaryotic translation initiation factor 5 [Homo
sapiens]
Length = 431
Score = 45.1 bits (105), Expect = 2e-04
Identities = 31/85 (36%), Positives = 47/85 (55%), Gaps = 5/85 (5%)
Query: 637 KRAADHLEALAAIEDFFLEHEALGIS-MAKVLMAFYQLEILAEETILSWFSQRDTTDKGQ 695
K+A +L L +E H+A IS + +L Y ++L EE I+SW + +
Sbjct: 308 KKAQRYL--LHGLECVVAMHQAQLISKIPHILKEMYDADLLEEEVIISWSEKASKKYVSK 365
Query: 696 QLRKNQQLQR--FIQWLKEAEEESS 718
+L K +++ FI+WLKEAEEESS
Sbjct: 366 ELAKEIRVKAEPFIKWLKEAEEESS 390
>gi|110630018 eukaryotic translation initiation factor 4 gamma, 2
isoform 2 [Homo sapiens]
Length = 869
Score = 44.7 bits (104), Expect = 3e-04
Identities = 38/153 (24%), Positives = 70/153 (45%), Gaps = 6/153 (3%)
Query: 572 DNLVLEINSLKYAYNISLKEVMQVLSHVVLEFPLQQMDSPLDSSRYCALLLPLLKAWSPV 631
DN+ +++ K NI + +Q +S V + S S LL ++ PV
Sbjct: 718 DNISPKLHVDKGFVNILMTSFLQYISSEVNPPSDETDSSSAPSKEQLEQEKQLLLSFKPV 777
Query: 632 FRNYIKRAAD-HLEALAAIEDFFLEHEALGISMAKVLMAFYQLEILAEETILSWFSQ--R 688
+ ++ D + AL A++ + + + FY +EI+ EE L+W +
Sbjct: 778 MQKFLHDHVDLQVSALYALQVHCYNSNFPKGMLLRFFVHFYDMEIIEEEAFLAWKEDITQ 837
Query: 689 DTTDKGQQLRKNQQLQRFIQWLKEAEEESSEDD 721
+ KG+ L Q+ +++ WL+ AEEE SE++
Sbjct: 838 EFPGKGKALF---QVNQWLTWLETAEEEESEEE 867
>gi|4503539 eukaryotic translation initiation factor 4 gamma, 2
isoform 1 [Homo sapiens]
Length = 907
Score = 44.7 bits (104), Expect = 3e-04
Identities = 38/153 (24%), Positives = 70/153 (45%), Gaps = 6/153 (3%)
Query: 572 DNLVLEINSLKYAYNISLKEVMQVLSHVVLEFPLQQMDSPLDSSRYCALLLPLLKAWSPV 631
DN+ +++ K NI + +Q +S V + S S LL ++ PV
Sbjct: 756 DNISPKLHVDKGFVNILMTSFLQYISSEVNPPSDETDSSSAPSKEQLEQEKQLLLSFKPV 815
Query: 632 FRNYIKRAAD-HLEALAAIEDFFLEHEALGISMAKVLMAFYQLEILAEETILSWFSQ--R 688
+ ++ D + AL A++ + + + FY +EI+ EE L+W +
Sbjct: 816 MQKFLHDHVDLQVSALYALQVHCYNSNFPKGMLLRFFVHFYDMEIIEEEAFLAWKEDITQ 875
Query: 689 DTTDKGQQLRKNQQLQRFIQWLKEAEEESSEDD 721
+ KG+ L Q+ +++ WL+ AEEE SE++
Sbjct: 876 EFPGKGKALF---QVNQWLTWLETAEEEESEEE 905
>gi|4504487 histidine rich calcium binding protein precursor [Homo
sapiens]
Length = 699
Score = 42.7 bits (99), Expect = 0.001
Identities = 25/93 (26%), Positives = 47/93 (50%), Gaps = 1/93 (1%)
Query: 449 ISLHPPDAEEDEDDGEFSDDSGADQEKDKVKMKGYNPAEVGAAGKGYLWKAAGMNMEEEE 508
+S HPP +D D +++EK+K + G + + ++ +G G +E+E
Sbjct: 461 MSHHPPGHTVVKDRSHLRKDD-SEEEKEKEEDPGSHEEDDESSEQGEKGTHHGSRDQEDE 519
Query: 509 ELQQNLWGLKINMEEESESESEQSMDSEEPDSR 541
E ++ GL +N EEE E + E+ + E+ + R
Sbjct: 520 EDEEEGHGLSLNQEEEEEEDKEEEEEEEDEERR 552
>gi|10092601 eukaryotic translation initiation factor 4 gamma, 3 [Homo
sapiens]
Length = 1585
Score = 40.4 bits (93), Expect = 0.006
Identities = 22/98 (22%), Positives = 47/98 (47%), Gaps = 1/98 (1%)
Query: 624 LLKAWSPVFRNYIKRAAD-HLEALAAIEDFFLEHEALGISMAKVLMAFYQLEILAEETIL 682
++K P+ Y+ + L+AL A++ ++ + + Y E+++E+
Sbjct: 1488 VIKQRVPILLKYLDSDTEKELQALYALQASIVKLDQPANLLRMFFDCLYDEEVISEDAFY 1547
Query: 683 SWFSQRDTTDKGQQLRKNQQLQRFIQWLKEAEEESSED 720
W S +D ++ + + + F WL+EAEEES ++
Sbjct: 1548 KWESSKDPAEQNGKGVALKSVTAFFTWLREAEEESEDN 1585
>gi|24415404 MDN1, midasin homolog [Homo sapiens]
Length = 5596
Score = 39.3 bits (90), Expect = 0.013
Identities = 27/118 (22%), Positives = 50/118 (42%), Gaps = 28/118 (23%)
Query: 451 LHPPDAEEDEDDGEFSDDSGADQEKDKVKMKGYNPAEVGAAGKGYLWKAAGMNMEEEEEL 510
+H + EE E+D E SD G D +K +N EE ++L
Sbjct: 4737 MHDGELEEQEEDDEKSDSEGGDLDK----------------------HMGDLNGEEADKL 4774
Query: 511 QQNLWGLKINMEEESESESEQSMDSEEPDSRGGSPQMDDIKVFQNEVLGTLQRGKEEN 568
+ LWG ++ E E E+ D++ ++ G + D V +++ L + K+++
Sbjct: 4775 DERLWG------DDDEEEDEEEEDNKTEETGPGMDEEDSELVAKDDNLDSGNSNKDKS 4826
>gi|11761619 GDP-mannose pyrophosphorylase B isoform 1 [Homo
sapiens]
Length = 387
Score = 38.5 bits (88), Expect = 0.022
Identities = 32/110 (29%), Positives = 52/110 (47%), Gaps = 12/110 (10%)
Query: 345 GPEVSLGHGSILEENVLLGSGTV-----IGSNCFITNSVIGPGCHIGDNVVLDQTYLWQG 399
GP VSLG G ++E+ V + TV I S+ ++ + ++G C +G V LW G
Sbjct: 269 GPNVSLGPGVVVEDGVCIRRCTVLRDARIRSHSWLESCIVGWRCRVGQWV-----SLWAG 323
Query: 400 VRVAAGAQIHQSLLCDNAEVKERVTLKPRSVLTSQVVVGPNITLPEGSVI 449
+ G + + L D A V ++ +VL V+V + L SV+
Sbjct: 324 LGGERGGEC--ACLPDKAYPLLEVRMENVTVLGEDVIVNDELYLNGASVL 371
>gi|55769548 PHD finger protein 14 isoform 2 [Homo sapiens]
Length = 888
Score = 37.4 bits (85), Expect = 0.049
Identities = 38/143 (26%), Positives = 58/143 (40%), Gaps = 12/143 (8%)
Query: 455 DAEEDEDDGEFSDDSGADQEKDKVKMKGYNPAEVGAAGKGYLWKAAGMNMEEEEELQQNL 514
D E+DED+G SD+ D+ D+ +PA G K K N ++EEL +
Sbjct: 235 DNEDDEDEGSGSDEDENDEGNDE---DHSSPASEGGCKKKKS-KVLSRNSADDEELTNDS 290
Query: 515 WGLKINMEEESESESEQSMDSEEPDSRGGSPQMDDIKVFQNEVLGTLQRGKEENISCDNL 574
L S+S+S + E S +MD I + LG +E I CDN
Sbjct: 291 LTL-------SQSKSNEDSLILEKSQNWSSQKMDHILIC-CVCLGDNSEDADEIIQCDNC 342
Query: 575 VLEINSLKYAYNISLKEVMQVLS 597
+ ++ Y + +M S
Sbjct: 343 GITVHEGCYGVDGESDSIMSSAS 365
>gi|55769550 PHD finger protein 14 isoform 1 [Homo sapiens]
Length = 948
Score = 37.4 bits (85), Expect = 0.049
Identities = 38/143 (26%), Positives = 58/143 (40%), Gaps = 12/143 (8%)
Query: 455 DAEEDEDDGEFSDDSGADQEKDKVKMKGYNPAEVGAAGKGYLWKAAGMNMEEEEELQQNL 514
D E+DED+G SD+ D+ D+ +PA G K K N ++EEL +
Sbjct: 235 DNEDDEDEGSGSDEDENDEGNDE---DHSSPASEGGCKKKKS-KVLSRNSADDEELTNDS 290
Query: 515 WGLKINMEEESESESEQSMDSEEPDSRGGSPQMDDIKVFQNEVLGTLQRGKEENISCDNL 574
L S+S+S + E S +MD I + LG +E I CDN
Sbjct: 291 LTL-------SQSKSNEDSLILEKSQNWSSQKMDHILIC-CVCLGDNSEDADEIIQCDNC 342
Query: 575 VLEINSLKYAYNISLKEVMQVLS 597
+ ++ Y + +M S
Sbjct: 343 GITVHEGCYGVDGESDSIMSSAS 365
>gi|157674363 protein phosphatase 1, regulatory subunit 15A [Homo
sapiens]
Length = 674
Score = 36.6 bits (83), Expect = 0.084
Identities = 26/79 (32%), Positives = 44/79 (55%), Gaps = 7/79 (8%)
Query: 455 DAEEDEDDGEFSD-DSGADQEKDKVKMKGYNPAEVGAAGKGYLWKAAGMNMEEEEELQQN 513
D EE+ED+ E D DSG+D+E+ + + PA G K ++++ G + EEEE+ +
Sbjct: 349 DTEEEEDEEEDEDSDSGSDEEEGEAEASSSTPA-TGVFLKSWVYQ-PGEDTEEEEDEDSD 406
Query: 514 LWGLKINMEEESESESEQS 532
+ E+E E+E+ S
Sbjct: 407 TG----SAEDEREAETSAS 421
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 36.6 bits (83), Expect = 0.084
Identities = 29/114 (25%), Positives = 51/114 (44%), Gaps = 10/114 (8%)
Query: 455 DAEEDEDDGEFSDDSGADQEKDKVKMKGYNPAEVG-AAGKGYLWKAAGMNMEEEEELQQN 513
+ EE+E +GE ++ + E+++ + KG E G G+ + G + E E E ++
Sbjct: 894 EGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEG 953
Query: 514 LWGLKINMEEESESESEQSMDSEEPDSRGGSPQMDDIKVFQNEVLGTLQRGKEE 567
W EEE E E E+ + E + G + + E G + G+EE
Sbjct: 954 EWE---GEEEEGEGEGEEEGEGEGEEGEGEGEEE------EGEGEGEEEEGEEE 998
Score = 35.4 bits (80), Expect = 0.19
Identities = 28/113 (24%), Positives = 56/113 (49%), Gaps = 10/113 (8%)
Query: 457 EEDEDDGEFSDDS-GADQEKDKVKMKGYNPAEVGAA-GKGYLWKAAGMNMEEEEELQQNL 514
EE E++GE ++ G +E+++ +++G E G G+ + G E+E E ++N
Sbjct: 997 EEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEEN- 1055
Query: 515 WGLKINMEEESESESEQSMDSEEPDSRGGSPQMDDIKVFQNEVLGTLQRGKEE 567
+ N EEE E E + EE + R + + +++ G+++ GK +
Sbjct: 1056 ---RRNREEEEEEEGKYQETGEEENERQDGEEYKKV----SKIKGSVKYGKHK 1101
Score = 35.0 bits (79), Expect = 0.24
Identities = 29/98 (29%), Positives = 42/98 (42%), Gaps = 12/98 (12%)
Query: 445 EGSVISLHPPDAEEDEDDGEFSDDSGADQEKDKVKMKGYNPAEVGAAGKGYLWKAAGMNM 504
EG + + EE+E++GE ++ G +E++ G E G GKG G
Sbjct: 815 EGGEVEEGKGEREEEEEEGEGEEEEGEGEEEE-----GEGEEEEG-EGKGEEEGEEGEGE 868
Query: 505 EEEEELQQNLWGLKINMEEESESESEQSMDSEEPDSRG 542
EE EE G EEE E E E+ + E + G
Sbjct: 869 EEGEE------GEGEGEEEEGEGEGEEEGEGEGEEEEG 900
Score = 31.2 bits (69), Expect = 3.5
Identities = 25/95 (26%), Positives = 38/95 (40%), Gaps = 18/95 (18%)
Query: 455 DAEEDEDDGEFSDDSGADQEKDKVKMKGYNPAEVGAAGKGYLWKAAGMNMEEEEELQQNL 514
+ E D+ +GE + G +EK+ E G G + + G EEEEE +
Sbjct: 788 EEEGDQGEGEEEETEGRGEEKE----------EGGEVEGGEVEEGKGEREEEEEEGE--- 834
Query: 515 WGLKINMEEESESESEQSMDSEEPDSRGGSPQMDD 549
EEE E E E+ EE G + ++
Sbjct: 835 -----GEEEEGEGEEEEGEGEEEEGEGKGEEEGEE 864
>gi|55749531 splicing factor 3B subunit 2 [Homo sapiens]
Length = 895
Score = 36.6 bits (83), Expect = 0.084
Identities = 23/68 (33%), Positives = 31/68 (45%), Gaps = 7/68 (10%)
Query: 482 GYNPAEVGAAGKGYLWKAAGMNMEE------EEELQQNLWG-LKINMEEESESESEQSMD 534
G+ V GK G N E EEE+ + WG L+ + EE SE E E+ D
Sbjct: 669 GWGKPPVDETGKPLYGDVFGTNAAEFQTKTEEEEIDRTPWGELEPSDEESSEEEEEEESD 728
Query: 535 SEEPDSRG 542
++PD G
Sbjct: 729 EDKPDETG 736
>gi|154355000 KH-type splicing regulatory protein [Homo sapiens]
Length = 711
Score = 35.8 bits (81), Expect = 0.14
Identities = 22/56 (39%), Positives = 27/56 (48%), Gaps = 10/56 (17%)
Query: 4 PVVAPPGVVVSRANKRSGAGPGGSG-GGGARGAEEEPP----PPLQAVLVADSFDR 54
P PPG A R G GPGG G GGG+ G +PP P ++ AD+ R
Sbjct: 30 PPPGPPG-----AGDRGGGGPGGGGPGGGSAGGPSQPPGGGGPGIRKDAFADAVQR 80
>gi|76150625 nucleolar protein 1, 120kDa [Homo sapiens]
Length = 808
Score = 35.4 bits (80), Expect = 0.19
Identities = 45/193 (23%), Positives = 80/193 (41%), Gaps = 39/193 (20%)
Query: 455 DAEED-----------EDDGEFSDDSGAD-QEKDKVKMKGYNPAEVGA-------AGKGY 495
D+EED EDD + DD GAD +D+ + + P E A A G
Sbjct: 115 DSEEDGMVNHGDLWGSEDDADTVDDYGADSNSEDEEEGEALLPIERAARKQKAREAAAGI 174
Query: 496 LWKAAGMNMEEEE----------ELQQNLWGLKINMEEES---ESESEQSMDSEEPDSRG 542
W EEEE ++++ GL+IN++EE E D++ PD +
Sbjct: 175 QWSEEETEDEEEEKEVTPESGPPKVEEADGGLQINVDEEPFVLPPAGEMEQDAQAPDLQR 234
Query: 543 GSPQMDDIKVFQNEVLGTLQRGKEENISCDNLVLEINSLKYAYNISLKEVMQVLSHVVLE 602
++ DI + + G+ + + L ++ ++ Y+Y L L ++
Sbjct: 235 VHKRIQDIVGILRDFGAQREEGRSRSEYLNRLKKDL-AIYYSYGDFL------LGKLMDL 287
Query: 603 FPLQQMDSPLDSS 615
FPL ++ L+++
Sbjct: 288 FPLSELVEFLEAN 300
>gi|76150623 nucleolar protein 1, 120kDa [Homo sapiens]
Length = 808
Score = 35.4 bits (80), Expect = 0.19
Identities = 45/193 (23%), Positives = 80/193 (41%), Gaps = 39/193 (20%)
Query: 455 DAEED-----------EDDGEFSDDSGAD-QEKDKVKMKGYNPAEVGA-------AGKGY 495
D+EED EDD + DD GAD +D+ + + P E A A G
Sbjct: 115 DSEEDGMVNHGDLWGSEDDADTVDDYGADSNSEDEEEGEALLPIERAARKQKAREAAAGI 174
Query: 496 LWKAAGMNMEEEE----------ELQQNLWGLKINMEEES---ESESEQSMDSEEPDSRG 542
W EEEE ++++ GL+IN++EE E D++ PD +
Sbjct: 175 QWSEEETEDEEEEKEVTPESGPPKVEEADGGLQINVDEEPFVLPPAGEMEQDAQAPDLQR 234
Query: 543 GSPQMDDIKVFQNEVLGTLQRGKEENISCDNLVLEINSLKYAYNISLKEVMQVLSHVVLE 602
++ DI + + G+ + + L ++ ++ Y+Y L L ++
Sbjct: 235 VHKRIQDIVGILRDFGAQREEGRSRSEYLNRLKKDL-AIYYSYGDFL------LGKLMDL 287
Query: 603 FPLQQMDSPLDSS 615
FPL ++ L+++
Sbjct: 288 FPLSELVEFLEAN 300
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 35.0 bits (79), Expect = 0.24
Identities = 24/85 (28%), Positives = 39/85 (45%), Gaps = 12/85 (14%)
Query: 455 DAEEDEDDGEFSDDSGADQEKDKVKMKGYNPAEVGAAGKGYLWKAAGMNMEEEEELQQNL 514
D E+DEDD + DD D E++ ++ PA+ A K KA + +E+EE
Sbjct: 188 DDEDDEDDEDDDDDEEDDSEEEAMET---TPAKGKKAAKVVPVKAKNVAEDEDEEEDD-- 242
Query: 515 WGLKINMEEESESESEQSMDSEEPD 539
E+E + + E D ++ D
Sbjct: 243 -------EDEDDDDDEDDEDDDDED 260
Score = 30.0 bits (66), Expect = 7.8
Identities = 23/86 (26%), Positives = 38/86 (44%), Gaps = 18/86 (20%)
Query: 455 DAEEDEDDGEFSDDSGADQEKDKVKMKGYNPAEVGAAGKGYLWKAAGMNMEEEEELQQNL 514
+A++++ D E DDS D+E D+ + + + E A KAA E+E
Sbjct: 139 NAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAA------MKAAAAAPASEDE----- 187
Query: 515 WGLKINMEEESESESEQSMDSEEPDS 540
++E + + E D EE DS
Sbjct: 188 -------DDEDDEDDEDDDDDEEDDS 206
>gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
Length = 1130
Score = 35.0 bits (79), Expect = 0.24
Identities = 24/100 (24%), Positives = 48/100 (48%), Gaps = 7/100 (7%)
Query: 438 GPNITLPEGSVISLHPPDAEEDEDDGEFSDDSGADQEKDKVKMKGYNPAEVGAAGKGYLW 497
GP + +VI+++ D EE+E++ E ++ ++E++ + + + E Y
Sbjct: 870 GPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEE-------YFE 922
Query: 498 KAAGMNMEEEEELQQNLWGLKINMEEESESESEQSMDSEE 537
+ E EEE ++ L+ EEE E E E+ + E+
Sbjct: 923 EEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVED 962
>gi|194248068 synaptic Ras GTPase activating protein 1 [Homo sapiens]
Length = 1343
Score = 35.0 bits (79), Expect = 0.24
Identities = 15/40 (37%), Positives = 24/40 (60%), Gaps = 1/40 (2%)
Query: 5 VVAPPGVVVSRANKRSGAGPGGSGGGGARGAEEEPPPPLQ 44
+++PP + + + + +GPGG GGG+ G PPPLQ
Sbjct: 1031 MLSPPQITIG-PQRPAPSGPGGGSGGGSGGGGGGQPPPLQ 1069
>gi|78486540 DDB1 and CUL4 associated factor 15 [Homo sapiens]
Length = 600
Score = 34.7 bits (78), Expect = 0.32
Identities = 24/71 (33%), Positives = 33/71 (46%), Gaps = 8/71 (11%)
Query: 14 SRANKRSGAGPGGSGGGGARG------AEEEPPPPLQAVLVADSFDRRFFPISKDQPRVL 67
S++ + SGAG GG G GGA G E L+ V ++ R F K PRV
Sbjct: 5 SKSERNSGAGSGGGGPGGAGGKRAAGRRREHVLKQLERVKISGQLSPRLF--RKLPPRVC 62
Query: 68 LPLANVALIDY 78
+ L N+ D+
Sbjct: 63 VSLKNIVDEDF 73
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.134 0.392
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,297,910
Number of Sequences: 37866
Number of extensions: 1361720
Number of successful extensions: 11535
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 55
Number of HSP's successfully gapped in prelim test: 101
Number of HSP's that attempted gapping in prelim test: 10804
Number of HSP's gapped (non-prelim): 599
length of query: 721
length of database: 18,247,518
effective HSP length: 110
effective length of query: 611
effective length of database: 14,082,258
effective search space: 8604259638
effective search space used: 8604259638
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.