Guide to the Human Genome
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Search of human proteins with 83035129

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|83035129 coiled-coil domain containing 108 isoform 1 [Homo
sapiens]
         (1925 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|83035129 coiled-coil domain containing 108 isoform 1 [Homo sa...  3956   0.0  
gi|83035133 coiled-coil domain containing 108 isoform 2 [Homo sa...   232   3e-60
gi|17975763 myelin transcription factor 1 [Homo sapiens]               70   3e-11
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    64   2e-09
gi|58761548 tau tubulin kinase 1 [Homo sapiens]                        63   3e-09
gi|221219020 NYD-SP11 protein [Homo sapiens]                           61   1e-08
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li...    61   1e-08
gi|119703749 hydrocephalus inducing isoform a [Homo sapiens]           61   1e-08
gi|46361983 hydrocephalus inducing isoform b [Homo sapiens]            61   1e-08
gi|239745093 PREDICTED: hypothetical protein XP_002343359 [Homo ...    60   3e-08
gi|60498973 myelin transcription factor 1-like [Homo sapiens]          59   5e-08
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom...    59   6e-08
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik...    58   8e-08
gi|4506411 Ran GTPase activating protein 1 [Homo sapiens]              58   1e-07
gi|169210053 PREDICTED: hypothetical protein [Homo sapiens]            57   1e-07
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]           57   1e-07
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]           57   1e-07
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi...    57   2e-07
gi|87298939 hypothetical protein LOC131831 [Homo sapiens]              57   2e-07
gi|210032580 SET domain containing 1B [Homo sapiens]                   57   2e-07
gi|211904182 DDB1 and CUL4 associated factor 8-like 2 [Homo sapi...    56   3e-07
gi|21735415 centromere protein B [Homo sapiens]                        56   3e-07
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li...    56   3e-07
gi|189409130 zinc finger E-box binding homeobox 1 isoform a [Hom...    56   4e-07
gi|189409128 zinc finger E-box binding homeobox 1 isoform b [Hom...    56   4e-07
gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isof...    56   4e-07
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)...    55   5e-07
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa...    55   7e-07
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa...    55   9e-07
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m...    54   1e-06

>gi|83035129 coiled-coil domain containing 108 isoform 1 [Homo
            sapiens]
          Length = 1925

 Score = 3956 bits (10260), Expect = 0.0
 Identities = 1925/1925 (100%), Positives = 1925/1925 (100%)

Query: 1    MFTLTGCRLVEKTQKVENPSVSFASSFPLIPLLLRGKSVQKKQAESKSQIKLHTQSAPFG 60
            MFTLTGCRLVEKTQKVENPSVSFASSFPLIPLLLRGKSVQKKQAESKSQIKLHTQSAPFG
Sbjct: 1    MFTLTGCRLVEKTQKVENPSVSFASSFPLIPLLLRGKSVQKKQAESKSQIKLHTQSAPFG 60

Query: 61   LCPKDMMLTQAPSSVVRSRNSRNHTVNSGGSCLSASTVAIPAINDSSAAMSACSTISAQP 120
            LCPKDMMLTQAPSSVVRSRNSRNHTVNSGGSCLSASTVAIPAINDSSAAMSACSTISAQP
Sbjct: 61   LCPKDMMLTQAPSSVVRSRNSRNHTVNSGGSCLSASTVAIPAINDSSAAMSACSTISAQP 120

Query: 121  ASSMDTQMHSPKKQERVNKRVIWGIEVAEELHWKGWELGKETTRNLVLKNRSLKLQKMKY 180
            ASSMDTQMHSPKKQERVNKRVIWGIEVAEELHWKGWELGKETTRNLVLKNRSLKLQKMKY
Sbjct: 121  ASSMDTQMHSPKKQERVNKRVIWGIEVAEELHWKGWELGKETTRNLVLKNRSLKLQKMKY 180

Query: 181  RPPKTKFFFTVIPQPIFLSPGITLTLPIVFRPLEAKEYMDQLWFEKAEGMFCVGLRATLP 240
            RPPKTKFFFTVIPQPIFLSPGITLTLPIVFRPLEAKEYMDQLWFEKAEGMFCVGLRATLP
Sbjct: 181  RPPKTKFFFTVIPQPIFLSPGITLTLPIVFRPLEAKEYMDQLWFEKAEGMFCVGLRATLP 240

Query: 241  CHRLICRPPSLQLPMCAVGDTTEAFFCLDNVGDLPTFFTWEFSSPFQMLPATGLLEPGQA 300
            CHRLICRPPSLQLPMCAVGDTTEAFFCLDNVGDLPTFFTWEFSSPFQMLPATGLLEPGQA
Sbjct: 241  CHRLICRPPSLQLPMCAVGDTTEAFFCLDNVGDLPTFFTWEFSSPFQMLPATGLLEPGQA 300

Query: 301  SQIKVTFQPLTAVIYEVQATCWYGAGSRQRSSIQLQAVAKCAQLLVSIKHKCPEDQDAEG 360
            SQIKVTFQPLTAVIYEVQATCWYGAGSRQRSSIQLQAVAKCAQLLVSIKHKCPEDQDAEG
Sbjct: 301  SQIKVTFQPLTAVIYEVQATCWYGAGSRQRSSIQLQAVAKCAQLLVSIKHKCPEDQDAEG 360

Query: 361  FQKLLYFGSVAVGCTSERQIRLHNPSAVNAPFRIEISPDELAEDQAFSCPTAHGIVLPGE 420
            FQKLLYFGSVAVGCTSERQIRLHNPSAVNAPFRIEISPDELAEDQAFSCPTAHGIVLPGE
Sbjct: 361  FQKLLYFGSVAVGCTSERQIRLHNPSAVNAPFRIEISPDELAEDQAFSCPTAHGIVLPGE 420

Query: 421  KKCVSVFFHPKTLDTRTVDYCSIMPSGCASKTLLKVVGFCRGPAVSLQHYCVNFSWVNLG 480
            KKCVSVFFHPKTLDTRTVDYCSIMPSGCASKTLLKVVGFCRGPAVSLQHYCVNFSWVNLG
Sbjct: 421  KKCVSVFFHPKTLDTRTVDYCSIMPSGCASKTLLKVVGFCRGPAVSLQHYCVNFSWVNLG 480

Query: 481  ERSEQPLWIENQSDCTAHFQFAIDCLESVFTIRPAFGTLVGKARMTLHCAFQPTHPIICF 540
            ERSEQPLWIENQSDCTAHFQFAIDCLESVFTIRPAFGTLVGKARMTLHCAFQPTHPIICF
Sbjct: 481  ERSEQPLWIENQSDCTAHFQFAIDCLESVFTIRPAFGTLVGKARMTLHCAFQPTHPIICF 540

Query: 541  RRVACLIHHQDPLFLDLMGTCHSDSTKPAILKPQHLTWYRTHLARGLTLYPPDILDAMLK 600
            RRVACLIHHQDPLFLDLMGTCHSDSTKPAILKPQHLTWYRTHLARGLTLYPPDILDAMLK
Sbjct: 541  RRVACLIHHQDPLFLDLMGTCHSDSTKPAILKPQHLTWYRTHLARGLTLYPPDILDAMLK 600

Query: 601  EKKLAQDQNGALMIPIQDLEDMPAPQYPYIPPMTEFFFDGTSDITIFPPPISVEPVEVDF 660
            EKKLAQDQNGALMIPIQDLEDMPAPQYPYIPPMTEFFFDGTSDITIFPPPISVEPVEVDF
Sbjct: 601  EKKLAQDQNGALMIPIQDLEDMPAPQYPYIPPMTEFFFDGTSDITIFPPPISVEPVEVDF 660

Query: 661  GACPGPEAPNPVPLCLMNHTKGKIMVVWTRRSDCPFWVTPESCDVPPLKSMAMRLHFQPP 720
            GACPGPEAPNPVPLCLMNHTKGKIMVVWTRRSDCPFWVTPESCDVPPLKSMAMRLHFQPP
Sbjct: 661  GACPGPEAPNPVPLCLMNHTKGKIMVVWTRRSDCPFWVTPESCDVPPLKSMAMRLHFQPP 720

Query: 721  HPNCLYTVELEAFAIYKVLQSYSNIEEDCTMCPSWCLTVRARGHSYFAGFEHHIPQYSLD 780
            HPNCLYTVELEAFAIYKVLQSYSNIEEDCTMCPSWCLTVRARGHSYFAGFEHHIPQYSLD
Sbjct: 721  HPNCLYTVELEAFAIYKVLQSYSNIEEDCTMCPSWCLTVRARGHSYFAGFEHHIPQYSLD 780

Query: 781  VPKLFPAVSSGEPTYRSLLLVNKDCKLLTFSLAPQRGSDVILRPTSGLVAPGAHQIILIC 840
            VPKLFPAVSSGEPTYRSLLLVNKDCKLLTFSLAPQRGSDVILRPTSGLVAPGAHQIILIC
Sbjct: 781  VPKLFPAVSSGEPTYRSLLLVNKDCKLLTFSLAPQRGSDVILRPTSGLVAPGAHQIILIC 840

Query: 841  TYPEGSSWKQHTFYLQCNASPQYLKEVSMYSREEPLQLKLDTHKSLYFKPTWVGCSSTSP 900
            TYPEGSSWKQHTFYLQCNASPQYLKEVSMYSREEPLQLKLDTHKSLYFKPTWVGCSSTSP
Sbjct: 841  TYPEGSSWKQHTFYLQCNASPQYLKEVSMYSREEPLQLKLDTHKSLYFKPTWVGCSSTSP 900

Query: 901  FTFRNPSRLPLQFEWRVSEQHRKLLAVQPSRGLIQPNERLTLTWTFSPLEETKYLFQVGM 960
            FTFRNPSRLPLQFEWRVSEQHRKLLAVQPSRGLIQPNERLTLTWTFSPLEETKYLFQVGM
Sbjct: 901  FTFRNPSRLPLQFEWRVSEQHRKLLAVQPSRGLIQPNERLTLTWTFSPLEETKYLFQVGM 960

Query: 961  WVWEAGLSPNANPAATTHYMLRLVGVGLTSSLSAKEKELAFGNVLVNSKQSRFLVLLNDG 1020
            WVWEAGLSPNANPAATTHYMLRLVGVGLTSSLSAKEKELAFGNVLVNSKQSRFLVLLNDG
Sbjct: 961  WVWEAGLSPNANPAATTHYMLRLVGVGLTSSLSAKEKELAFGNVLVNSKQSRFLVLLNDG 1020

Query: 1021 NCTLYYRLYLEQGSPEAVDNHPLALQLDRTEGSMPPRSQDTICLTACPKQRSQYSWTITY 1080
            NCTLYYRLYLEQGSPEAVDNHPLALQLDRTEGSMPPRSQDTICLTACPKQRSQYSWTITY
Sbjct: 1021 NCTLYYRLYLEQGSPEAVDNHPLALQLDRTEGSMPPRSQDTICLTACPKQRSQYSWTITY 1080

Query: 1081 SLLSHRDNKAGEKQELCCVSLVAVYPLLSILDVSSMGSAEGITRKHLWRLFSLDLLNSYL 1140
            SLLSHRDNKAGEKQELCCVSLVAVYPLLSILDVSSMGSAEGITRKHLWRLFSLDLLNSYL
Sbjct: 1081 SLLSHRDNKAGEKQELCCVSLVAVYPLLSILDVSSMGSAEGITRKHLWRLFSLDLLNSYL 1140

Query: 1141 ERDPTPCELTYKVPTRHSMSQIPPVLTPLRLDFNFGAAPFKAPPSVVFLALKNSGVVSLD 1200
            ERDPTPCELTYKVPTRHSMSQIPPVLTPLRLDFNFGAAPFKAPPSVVFLALKNSGVVSLD
Sbjct: 1141 ERDPTPCELTYKVPTRHSMSQIPPVLTPLRLDFNFGAAPFKAPPSVVFLALKNSGVVSLD 1200

Query: 1201 WAFLLPSDQRIDVELWAEQAELNSTELHQMRVQDNCLFSISPKAGSLSPGQEQMVELKYS 1260
            WAFLLPSDQRIDVELWAEQAELNSTELHQMRVQDNCLFSISPKAGSLSPGQEQMVELKYS
Sbjct: 1201 WAFLLPSDQRIDVELWAEQAELNSTELHQMRVQDNCLFSISPKAGSLSPGQEQMVELKYS 1260

Query: 1261 HLFIGTDHLPVLFKVSHGREILLNFIGVTVKPEQKYVHFTSTTHQFIPIPIGDTLPPRQI 1320
            HLFIGTDHLPVLFKVSHGREILLNFIGVTVKPEQKYVHFTSTTHQFIPIPIGDTLPPRQI
Sbjct: 1261 HLFIGTDHLPVLFKVSHGREILLNFIGVTVKPEQKYVHFTSTTHQFIPIPIGDTLPPRQI 1320

Query: 1321 YELYNGGSVPVTYEVQTDVLSQVQEKNFDHPIFCCLNPKGEIQPGSTARVLWIFSPIEAK 1380
            YELYNGGSVPVTYEVQTDVLSQVQEKNFDHPIFCCLNPKGEIQPGSTARVLWIFSPIEAK
Sbjct: 1321 YELYNGGSVPVTYEVQTDVLSQVQEKNFDHPIFCCLNPKGEIQPGSTARVLWIFSPIEAK 1380

Query: 1381 TYTVDVPIHILGWNSALIHFQGVGYNPHMMGDTAPFHNISSWDNSSIHSRLVVPGQNVFL 1440
            TYTVDVPIHILGWNSALIHFQGVGYNPHMMGDTAPFHNISSWDNSSIHSRLVVPGQNVFL
Sbjct: 1381 TYTVDVPIHILGWNSALIHFQGVGYNPHMMGDTAPFHNISSWDNSSIHSRLVVPGQNVFL 1440

Query: 1441 SQSHISLGNIPVQSKCSRLLFLNNISKNEEIAFSWQPSPLDFGEVSVSPMIGVVAPEETV 1500
            SQSHISLGNIPVQSKCSRLLFLNNISKNEEIAFSWQPSPLDFGEVSVSPMIGVVAPEETV
Sbjct: 1441 SQSHISLGNIPVQSKCSRLLFLNNISKNEEIAFSWQPSPLDFGEVSVSPMIGVVAPEETV 1500

Query: 1501 PFVVTLRASVHASFYSADLVCKLYSQQLMRQYHKELQEWKDEKVRQEVEFTITDMKVKKR 1560
            PFVVTLRASVHASFYSADLVCKLYSQQLMRQYHKELQEWKDEKVRQEVEFTITDMKVKKR
Sbjct: 1501 PFVVTLRASVHASFYSADLVCKLYSQQLMRQYHKELQEWKDEKVRQEVEFTITDMKVKKR 1560

Query: 1561 TCCTACEPARKYKTLPPIKNQQSVSRPASWKLQTPKEEVSWPCPQPPSPGMLCLGLTARA 1620
            TCCTACEPARKYKTLPPIKNQQSVSRPASWKLQTPKEEVSWPCPQPPSPGMLCLGLTARA
Sbjct: 1561 TCCTACEPARKYKTLPPIKNQQSVSRPASWKLQTPKEEVSWPCPQPPSPGMLCLGLTARA 1620

Query: 1621 HATDYFLANFFSEFPCHFLHRELPKRKAPREESETSEEKSPNKWGPVSKQKKQLLVDILT 1680
            HATDYFLANFFSEFPCHFLHRELPKRKAPREESETSEEKSPNKWGPVSKQKKQLLVDILT
Sbjct: 1621 HATDYFLANFFSEFPCHFLHRELPKRKAPREESETSEEKSPNKWGPVSKQKKQLLVDILT 1680

Query: 1681 TIIRGLLEDKNFHEAVDQSLVEQVPYFRQFWNEQSTKFMDQKNSLYLMPILPVPSSSWED 1740
            TIIRGLLEDKNFHEAVDQSLVEQVPYFRQFWNEQSTKFMDQKNSLYLMPILPVPSSSWED
Sbjct: 1681 TIIRGLLEDKNFHEAVDQSLVEQVPYFRQFWNEQSTKFMDQKNSLYLMPILPVPSSSWED 1740

Query: 1741 GKGKQPKEDRPEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEE 1800
            GKGKQPKEDRPEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEE
Sbjct: 1741 GKGKQPKEDRPEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEE 1800

Query: 1801 ERDEKEEKVSWAGIGPTPQPESQESMQWQWQQQLNVMVKEEQEQDEKEAIRRLPAFANLQ 1860
            ERDEKEEKVSWAGIGPTPQPESQESMQWQWQQQLNVMVKEEQEQDEKEAIRRLPAFANLQ
Sbjct: 1801 ERDEKEEKVSWAGIGPTPQPESQESMQWQWQQQLNVMVKEEQEQDEKEAIRRLPAFANLQ 1860

Query: 1861 EALLENMIQNILVEASRGEVVLTSRPRVIALPPFCVPRSLTPDTLLPTQQAEVLHPVVPL 1920
            EALLENMIQNILVEASRGEVVLTSRPRVIALPPFCVPRSLTPDTLLPTQQAEVLHPVVPL
Sbjct: 1861 EALLENMIQNILVEASRGEVVLTSRPRVIALPPFCVPRSLTPDTLLPTQQAEVLHPVVPL 1920

Query: 1921 PTDLP 1925
            PTDLP
Sbjct: 1921 PTDLP 1925


>gi|83035133 coiled-coil domain containing 108 isoform 2 [Homo
           sapiens]
          Length = 164

 Score =  232 bits (591), Expect = 3e-60
 Identities = 116/116 (100%), Positives = 116/116 (100%)

Query: 66  MMLTQAPSSVVRSRNSRNHTVNSGGSCLSASTVAIPAINDSSAAMSACSTISAQPASSMD 125
           MMLTQAPSSVVRSRNSRNHTVNSGGSCLSASTVAIPAINDSSAAMSACSTISAQPASSMD
Sbjct: 1   MMLTQAPSSVVRSRNSRNHTVNSGGSCLSASTVAIPAINDSSAAMSACSTISAQPASSMD 60

Query: 126 TQMHSPKKQERVNKRVIWGIEVAEELHWKGWELGKETTRNLVLKNRSLKLQKMKYR 181
           TQMHSPKKQERVNKRVIWGIEVAEELHWKGWELGKETTRNLVLKNRSLKLQKMKYR
Sbjct: 61  TQMHSPKKQERVNKRVIWGIEVAEELHWKGWELGKETTRNLVLKNRSLKLQKMKYR 116


>gi|17975763 myelin transcription factor 1 [Homo sapiens]
          Length = 1121

 Score = 69.7 bits (169), Expect = 3e-11
 Identities = 43/106 (40%), Positives = 60/106 (56%), Gaps = 10/106 (9%)

Query: 1757 LGKKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEK-------- 1808
            L  +EE EEE+ EEEEEE +EEEEEEEE EEEE  +EE EE+EEE +E+EE+        
Sbjct: 255  LSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQ 314

Query: 1809 --VSWAGIGPTPQPESQESMQWQWQQQLNVMVKEEQEQDEKEAIRR 1852
               S       P+    ES   + +  + V V+ + ++DE    R+
Sbjct: 315  EDTSHTSAQKAPELRGPESPSPKPEYSVIVEVRSDDDKDEDTHSRK 360



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 29/49 (59%), Positives = 37/49 (75%), Gaps = 1/49 (2%)

Query: 1761 EEGEEEKGE-EEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEK 1808
            EE  ++KG    EEE EEEEEEEEE EE+E  +EE EE+EEE +E+EE+
Sbjct: 246  EESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEE 294



 Score = 31.6 bits (70), Expect = 7.8
 Identities = 24/92 (26%), Positives = 48/92 (52%), Gaps = 6/92 (6%)

Query: 1761 EEGEE--EKGEEEEEELEEEEEEEEETEEEELGKEEIE-EKEEERDEKEEKVSWAGIGPT 1817
            E+ EE  E   E  ++L  +  E+  +EE    K  +  E+E+E +E+EE+         
Sbjct: 219  EDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEE---DE 275

Query: 1818 PQPESQESMQWQWQQQLNVMVKEEQEQDEKEA 1849
             + E +E  + + +++     +EE+E++E+EA
Sbjct: 276  EEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEA 307


>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
            sapiens]
          Length = 1130

 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 54/172 (31%), Positives = 80/172 (46%), Gaps = 40/172 (23%)

Query: 1741 GKGKQPKEDRPEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEE 1800
            G G  P  +       +   +E EEE+ EEEEEE EEEEEEE+  EEEE  +E  EE+EE
Sbjct: 867  GGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEE 926

Query: 1801 ERDEKEEKVSWAGIGPTPQPESQESMQWQWQQQLNVMVKEEQEQDEKEAIRRLPAFANLQ 1860
            E +E EE                     +++++   + +EE+E+DE+E           +
Sbjct: 927  EEEEFEE---------------------EFEEEEGELEEEEEEEDEEE-----------E 954

Query: 1861 EALLENMIQNILVEASRGEVVLTSRPRVIALPPFCVPRSLTPDTLLPTQQAE 1912
            E L E  ++++    + GEV         A PP  +P +L P    P  Q E
Sbjct: 955  EELEE--VEDLEFGTAGGEV------EEGAPPPPTLPPALPPPESPPKVQPE 998



 Score = 58.9 bits (141), Expect = 5e-08
 Identities = 46/140 (32%), Positives = 73/140 (52%), Gaps = 19/140 (13%)

Query: 1728 MPILPVPSSSWEDGKGKQPKEDRPEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETEE 1787
            + ++ + SS  E+ + ++ +E+  E        EE EE++ E  EEE EEEEE EEE EE
Sbjct: 878  LTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEE 937

Query: 1788 EELGKEEIEEKEEERDEKE-EKVSWAGIG-------------PT-----PQPESQESMQW 1828
            EE   EE EE+E+E +E+E E+V     G             PT     P PES   +Q 
Sbjct: 938  EEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQP 997

Query: 1829 QWQQQLNVMVKEEQEQDEKE 1848
            + + +  ++++ E+   E+E
Sbjct: 998  EPEPEPGLLLEVEEPGTEEE 1017


>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
          Length = 1321

 Score = 62.8 bits (151), Expect = 3e-09
 Identities = 36/70 (51%), Positives = 43/70 (61%), Gaps = 9/70 (12%)

Query: 1758 GKKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEKVSWAGIGPT 1817
            GK+EE EEE+ EEEEEE EEEEEEEEE EEEE         EEE +E+EE  +   +G  
Sbjct: 731  GKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEE---------EEEEEEEEEAAAAVALGEV 781

Query: 1818 PQPESQESMQ 1827
              P S  S +
Sbjct: 782  LGPRSGSSSE 791



 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 31/62 (50%), Positives = 37/62 (59%), Gaps = 11/62 (17%)

Query: 1728 MPILPVPSSSWEDGKGKQPKEDRPEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETEE 1787
            +P+ PV   +     GK+ +E+  E        EE EEE  EEEEEE EEEEEEEEE EE
Sbjct: 720  VPLAPVQPQA----NGKEEEEEEEED-------EEEEEEDEEEEEEEEEEEEEEEEEEEE 768

Query: 1788 EE 1789
            EE
Sbjct: 769  EE 770



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 27/66 (40%), Positives = 38/66 (57%), Gaps = 7/66 (10%)

Query: 1727 LMPILPVPSSSWEDGKGKQPKEDRPEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETE 1786
            L P+ P  +   E+ + ++ +E+  E       +EE EEE+ EEEEEE EEEEEEEE   
Sbjct: 722  LAPVQPQANGKEEEEEEEEDEEEEEED------EEEEEEEEEEEEEEE-EEEEEEEEAAA 774

Query: 1787 EEELGK 1792
               LG+
Sbjct: 775  AVALGE 780



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 30/85 (35%), Positives = 40/85 (47%), Gaps = 40/85 (47%)

Query: 1765 EEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEKVSWAGIGPTPQPESQE 1824
            +  G+EEEEE EE+EEEEEE EEEE         EEE +E+EE+                
Sbjct: 728  QANGKEEEEEEEEDEEEEEEDEEEE---------EEEEEEEEEE---------------- 762

Query: 1825 SMQWQWQQQLNVMVKEEQEQDEKEA 1849
                           EE+E++E+EA
Sbjct: 763  ---------------EEEEEEEEEA 772


>gi|221219020 NYD-SP11 protein [Homo sapiens]
          Length = 2873

 Score = 60.8 bits (146), Expect = 1e-08
 Identities = 53/194 (27%), Positives = 90/194 (46%), Gaps = 16/194 (8%)

Query: 1702 EQVPYFRQFWNEQSTKFMDQKNSLYLMPILPVPSSSWEDGKGKQPKEDRPEHYPGLGKKE 1761
            E +P+ ++ W ++       K        +    S     +  +   D  E    L  +E
Sbjct: 2188 EVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEE 2247

Query: 1762 EGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEKVSWAGIGPTPQPE 1821
            E  EE+ EEEE E EE  EEEEE +EEE G+E+  EKEEE  +K++K          + E
Sbjct: 2248 E--EEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKK--------EKKKE 2297

Query: 1822 SQESMQWQWQQQLNVMVKEEQE----QDEKEAIRRLPAFANLQEALLENMIQNILVEASR 1877
              +  +  ++++  +M +EE E    ++E+E    L    + ++ +L+   Q  L E  R
Sbjct: 2298 EVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQRR 2357

Query: 1878 GEVVLTSRPRVIAL 1891
                L  R RV+++
Sbjct: 2358 KS--LRGRERVLSI 2369



 Score = 39.7 bits (91), Expect = 0.029
 Identities = 38/156 (24%), Positives = 63/156 (40%), Gaps = 41/156 (26%)

Query: 1762 EGEEEKGEEEEE------------------------------ELEEEEEEEEETE----- 1786
            + EEE G EEEE                              E+E EE   EE E     
Sbjct: 2177 DDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDE 2236

Query: 1787 ---EEELGKEEIEEKEEERDEKEEKVSWAGIGPTPQPESQESMQWQWQQQLNVMVKEEQE 1843
               +E L  EE EE+EEE + +EE+V         + E +E  + Q +++     K+++E
Sbjct: 2237 LEKQESLSSEEEEEREEEEEREEEEVREE---EEERKEEEEGEEKQVEKEEEEKKKKKKE 2293

Query: 1844 QDEKEAIRRLPAFANLQEALLENMIQNILVEASRGE 1879
            + ++E   +   F   +E + E   +++  E    E
Sbjct: 2294 KKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEE 2329



 Score = 39.3 bits (90), Expect = 0.038
 Identities = 31/125 (24%), Positives = 64/125 (51%), Gaps = 8/125 (6%)

Query: 1745 QPKEDRPEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDE 1804
            Q  E+ P+    L  +E+   ++ EE E ++EE   +EEE  +EE GK  + E++++  E
Sbjct: 1695 QKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEE-GK--LVEEKKKLAE 1751

Query: 1805 KEEKVSWAGIGPTPQPESQESMQWQWQQQLNVMVKEEQEQDEKEAIRRLPAFANLQEALL 1864
            +EE ++W       +  S+E  +   +++L +  KE+  Q +++           +E L+
Sbjct: 1752 EEEALAW-----QREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLI 1806

Query: 1865 ENMIQ 1869
            E  ++
Sbjct: 1807 EKKMK 1811



 Score = 35.8 bits (81), Expect = 0.41
 Identities = 27/112 (24%), Positives = 50/112 (44%), Gaps = 10/112 (8%)

Query: 1764 EEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEE----------RDEKEEKVSWAG 1813
            E++  +EEE  LEEE   E E +E+++ +E+   +EE           R EK+       
Sbjct: 1535 EQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERK 1594

Query: 1814 IGPTPQPESQESMQWQWQQQLNVMVKEEQEQDEKEAIRRLPAFANLQEALLE 1865
            +    +  +QE  Q   +++       +  QD++E  +    FA  +E L +
Sbjct: 1595 LAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQ 1646



 Score = 34.7 bits (78), Expect = 0.92
 Identities = 28/100 (28%), Positives = 49/100 (49%), Gaps = 15/100 (15%)

Query: 1764 EEEKGEEEEEELEEEEEEEEETEEEELGKEEIE-----------EKEEERDEKEEKVSWA 1812
            +EEK  EEE +L  +  E    +EEE G EE E            KE +R +K ++   +
Sbjct: 2156 KEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSS 2215

Query: 1813 GIGPTPQ----PESQESMQWQWQQQLNVMVKEEQEQDEKE 1848
             +          E  ES+  + ++Q ++  +EE+E++E+E
Sbjct: 2216 QVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEE 2255



 Score = 33.9 bits (76), Expect = 1.6
 Identities = 55/236 (23%), Positives = 98/236 (41%), Gaps = 48/236 (20%)

Query: 1651 EESETSEEKSPNKWGPVSKQKKQLLVDILTTIIRG--LLEDKNFHEAVDQSLVEQVPYFR 1708
            E+     +K   KW  V++++++L         +G  L E KN    +    VE++P   
Sbjct: 1656 EKLAQKRKKLAKKWEKVAREEEKLAK-------KGGKLAEVKN----ILAQKVEELPQRE 1704

Query: 1709 QFWNEQSTKFMDQKNSLYLMPILPVPSSSW-------EDGKGKQPKEDRPEHYPGLG--- 1758
            Q  + Q  +   +   L       +   SW       E+GK  + K+   E    L    
Sbjct: 1705 QNLDWQEKELAQELEELEW----DMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQR 1760

Query: 1759 -KKEEGEEEKGEEEEEELEEEE-----EEEEETEEEELG--KEEIEEKEEERDEKEEKVS 1810
             K  E E +  +EEE  ++E+E     +E+   EEE LG  +E++ EK+ +  +K E+  
Sbjct: 1761 EKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRER-- 1818

Query: 1811 WAGIGPTPQPESQESMQWQWQQQLNVMVKEEQEQDEKEAIRRLPAFANLQEALLEN 1866
            W             SM+   + ++ +  K+   Q++K   +     A  +E LL N
Sbjct: 1819 WI-----------NSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYN 1863



 Score = 32.7 bits (73), Expect = 3.5
 Identities = 45/204 (22%), Positives = 87/204 (42%), Gaps = 46/204 (22%)

Query: 1646 RKAPREESETSEEKSPNKWGPVSKQKKQLLVDILTTIIRGLLEDKNFHEAVDQSLVEQVP 1705
            ++  ++E + + +KSP K G  + QK++ +  I   + +   E+++  E V++    +  
Sbjct: 1385 KEISKKEEKKTFQKSP-KQGRKAVQKERKVGKIKREMTK---EERDMSEEVEEMATLE-- 1438

Query: 1706 YFRQFWNEQSTKFMDQKNSLYLMPILPVPSSSWEDGKGKQPKEDRPEHYPGLGKKEEGEE 1765
                       K + Q+  L ++   P    SW+D K    +           K+  GE 
Sbjct: 1439 ----------EKVVKQEGKLVMIERTP----SWQDWKKAWDE----------WKQVHGET 1474

Query: 1766 EKGEEE-EEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEKVSWAGIGPTPQPESQE 1824
             K  +  +EE E+   +EEE   +     E    EEE  ++++K+ W            E
Sbjct: 1475 RKSWKAWKEEWEKRLLQEEEKLHQ---AGEKLSPEEEMLQEDKKLKW------------E 1519

Query: 1825 SMQWQWQQQLNVMVKEEQEQDEKE 1848
              +  W+  L+   KE+Q +DE+E
Sbjct: 1520 EWKQVWENMLSSKSKEQQYKDEEE 1543


>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
            [Homo sapiens]
          Length = 828

 Score = 60.8 bits (146), Expect = 1e-08
 Identities = 57/219 (26%), Positives = 96/219 (43%), Gaps = 44/219 (20%)

Query: 1641 RELPKRKAPREESETSEEKSPNKWGPVSKQKKQLLVDILTTIIRGLLEDKNFHEAVDQSL 1700
            +EL ++K  RE+ E  +E+    W    K ++Q              E+K + +  ++ L
Sbjct: 297  KELREQKKLREQEEQMQEQEEKMWEQEEKMREQ--------------EEKMWRQ--EERL 340

Query: 1701 VEQVPYFRQFWNEQSTKFMDQKNSLYLMPILPVPSSSWEDGKGKQPKEDRPEHYPGLGKK 1760
             EQ    R    EQ  K  DQ+  +            WE  +  + KE+R        ++
Sbjct: 341  WEQEKQMR----EQEQKMRDQEERM------------WEQDERLREKEERMRE-----QE 379

Query: 1761 EEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEKVSWAGIGPTPQP 1820
            +  E+E+  +EEE + E E++  E EE    +EE  +K+EE   ++E+  W       Q 
Sbjct: 380  KMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQK 439

Query: 1821 E---SQESMQWQ----WQQQLNVMVKEEQEQDEKEAIRR 1852
            E    QE MQ Q    W+Q+  +  +EE    EK+  R+
Sbjct: 440  EKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQ 478



 Score = 58.2 bits (139), Expect = 8e-08
 Identities = 54/218 (24%), Positives = 101/218 (46%), Gaps = 24/218 (11%)

Query: 1650 REESETSEEKSPNKWGPVSKQKKQLLVDILTTIIRGLLEDKNFHEAVDQSLVEQVPYFRQ 1709
            REE +T E++    W    K +++   + +    + + E++      ++ + EQ    R+
Sbjct: 537  REEKKTQEQEKKT-WDQEEKMREE---ERMREREKKMREEEEMMREQEEKMQEQEEKMRE 592

Query: 1710 ----FWNEQSTKFMDQKNSLYLMPILPVPSSSWEDGKGKQPKEDRPEHYPGLGKKEEGEE 1765
                 W EQ  K  +Q+  ++           WE  +  + +E     +    K +E EE
Sbjct: 593  QEEKMW-EQEEKMQEQEEKMWEQE-----EKMWEQEEEDKMQEQEEMMWEQEEKMQEQEE 646

Query: 1766 EKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEKVSWAGIGPTPQPE---S 1822
            +  E+EE+  E+EE+  E+ E+ +  +E++ E+EE+   +EEK+         Q E    
Sbjct: 647  KMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWG 706

Query: 1823 QESMQW-----QWQQQLNVMVKEEQEQDEKEAIR-RLP 1854
            QE   W      W Q+  +  KEE+ +D+KE ++ RLP
Sbjct: 707  QEEKMWGQEEKMWGQE-EMREKEERIRDQKEKMQERLP 743



 Score = 51.2 bits (121), Expect = 1e-05
 Identities = 30/90 (33%), Positives = 53/90 (58%), Gaps = 5/90 (5%)

Query: 1758 GKKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEKVSWAGIGPT 1817
            GK  E +EEK   +E+ L E+E+E  E E+E   ++++ E+EE+  E+EEK+ W      
Sbjct: 269  GKMRE-QEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKM-WE---QE 323

Query: 1818 PQPESQESMQWQWQQQLNVMVKEEQEQDEK 1847
             +   QE   W+ +++L    K+ +EQ++K
Sbjct: 324  EKMREQEEKMWRQEERLWEQEKQMREQEQK 353



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 30/114 (26%), Positives = 63/114 (55%), Gaps = 4/114 (3%)

Query: 1739 EDGKGKQPKED--RPEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIE 1796
            ++GK ++ +E   R E      +KE  E+EK   E+++L E+EE+ +E EE+   +EE  
Sbjct: 267  QEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKM 326

Query: 1797 EKEEERDEKEEKVSWAGIGPTPQPES--QESMQWQWQQQLNVMVKEEQEQDEKE 1848
             ++EE+  ++E+  W       + E   ++  +  W+Q   +  KEE+ +++++
Sbjct: 327  REQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEK 380



 Score = 43.1 bits (100), Expect = 0.003
 Identities = 35/144 (24%), Positives = 72/144 (50%), Gaps = 28/144 (19%)

Query: 1726 YLMPILPVPSSSWEDGKGKQPKEDRPEHYPGLGKKEEGEEEKGEEEEEELEEEE------ 1779
            +L+P   V +++ ++   +Q +E R +      KK   +EEK   +EE L E+E      
Sbjct: 222  FLLP--QVQTNTLQEEMWRQEEELREQE-----KKIRKQEEKMWRQEERLREQEGKMREQ 274

Query: 1780 EEEEETEEEELGKEEIEEKEEERDEKEEKVSWAGIGPTPQPESQESMQWQ---------- 1829
            EE+   +E+ L ++E E +E+E++ +E+K          Q + QE   W+          
Sbjct: 275  EEKMRRQEKRLREQEKELREQEKELREQKKLRE---QEEQMQEQEEKMWEQEEKMREQEE 331

Query: 1830 --WQQQLNVMVKEEQEQDEKEAIR 1851
              W+Q+  +  +E+Q +++++ +R
Sbjct: 332  KMWRQEERLWEQEKQMREQEQKMR 355



 Score = 40.4 bits (93), Expect = 0.017
 Identities = 43/179 (24%), Positives = 76/179 (42%), Gaps = 32/179 (17%)

Query: 1651 EESETSEEKSPNKWGPVSKQKKQLLVDILTTIIRGLLEDKNFHEAVDQSLVEQVPYFRQF 1710
            E+ E  +E+    W    K  +Q   D +      + E +   +  ++ + EQ    R  
Sbjct: 599  EQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMR-- 656

Query: 1711 WNEQSTKFMDQKNSLYLMPILPVPSSSWEDGKGKQPK-EDRPEHYPGLGKKEEGEEEKGE 1769
              EQ  K  +Q+  +                +G++ K  ++ E   G  +K   +EEK  
Sbjct: 657  --EQEEKMREQEEKM----------------QGQEEKMREQEEKMQGQEEKMREQEEKMR 698

Query: 1770 EEEEELEEEEEEEEETEEEELGKEEIEEKEEE-RDEK----------EEKVSWAGIGPT 1817
             +EE++  +EE+    EE+  G+EE+ EKEE  RD+K          EE+ S   + P+
Sbjct: 699  GQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEERCSEPCLPPS 757



 Score = 39.3 bits (90), Expect = 0.038
 Identities = 25/108 (23%), Positives = 54/108 (50%)

Query: 1764 EEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEKVSWAGIGPTPQPESQ 1823
            +EEK  E+EE++ E+EE+    EE    +E+   ++E++   +E+  W       + E +
Sbjct: 315  QEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEER 374

Query: 1824 ESMQWQWQQQLNVMVKEEQEQDEKEAIRRLPAFANLQEALLENMIQNI 1871
               Q +  +Q   M +EE+ ++ ++ +R        QE  ++   +N+
Sbjct: 375  MREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENM 422



 Score = 38.1 bits (87), Expect = 0.084
 Identities = 40/206 (19%), Positives = 89/206 (43%), Gaps = 36/206 (17%)

Query: 1645 KRKAPREESETSEEKSPNKWGPVSKQKKQLLVDILTTIIRGLLEDKNFHEAVDQSLVEQV 1704
            + K  REE ET  E+       + KQ++ +             E+K + +   Q L EQ 
Sbjct: 397  REKKMREEEETMREQEEK----MQKQEENMWEQ----------EEKEWQQ---QRLPEQK 439

Query: 1705 PYFRQFWNEQSTKFMDQKNSLYLMPILPVPSSSWEDGKGKQPKEDRPEHYPGLGKKEEGE 1764
                + W ++  +  ++K               WE  +  + +E+       + ++E+  
Sbjct: 440  ---EKLWEQEKMQEQEEK--------------IWEQEEKIRDQEEMWGQEKKMWRQEKMR 482

Query: 1765 EEKGEE-EEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEKVSWAGIGP-TPQPES 1822
            E++ +  E+EE   ++E++   +EE + +++   +E+E   +E+K  W        + ++
Sbjct: 483  EQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKT 542

Query: 1823 QESMQWQWQQQLNVMVKEEQEQDEKE 1848
            QE  +  W Q+  +  +E   + EK+
Sbjct: 543  QEQEKKTWDQEEKMREEERMREREKK 568


>gi|119703749 hydrocephalus inducing isoform a [Homo sapiens]
          Length = 5120

 Score = 60.8 bits (146), Expect = 1e-08
 Identities = 53/242 (21%), Positives = 99/242 (40%), Gaps = 19/242 (7%)

Query: 166 LVLKNRSLKLQKMKYRPPKTKFFFTVIPQPIF--LSPGITLTLPIVFRPLEAKEYMDQLW 223
           L+L+N     + +K     + +F  + P+ I   ++PG+     I+F P E K+Y   L 
Sbjct: 120 LILRNNDKIPRLVKVVEESSPYFKVISPKDIGHKVAPGVPSIFRILFTPEENKDYAHTLT 179

Query: 224 FEKAEGMFCVGLRATLPCHRLICRPPSLQLPMCAVGDTTEAFFCLDNVGDLPTFFTWEFS 283
                  F V ++A      ++  P  L    C V  +T+    + N+G+    F  +  
Sbjct: 180 CVTEREKFIVPIKAR-GARAILDFPDKLNFSTCPVKYSTQKILLVRNIGNKNAVFHIKTC 238

Query: 284 SPFQMLPATGLLEPGQASQIKVTFQPLTAVIYEVQATCWYGAGSRQRSSIQLQAVAKCAQ 343
            PF + PA G L  G++ Q++V F+P +   +  +    Y  G +   S+   A+     
Sbjct: 239 RPFSIEPAIGTLNVGESMQLEVEFEPQSVGDHSGRLIVCYDTGEKVFVSLYGAAI----- 293

Query: 344 LLVSIKHKCPEDQDAEGFQKLLYFGSVAVGCTSERQIRLHNPSAVNAPFRIEISPDELAE 403
                      D +    +  L      +   ++R I +HN S + A F  ++   +  E
Sbjct: 294 -----------DMNIRLDKNSLTIEKTYISLANQRTITIHNRSNIIAHFLWKVFATQQEE 342

Query: 404 DQ 405
           D+
Sbjct: 343 DR 344



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 59/276 (21%), Positives = 111/276 (40%), Gaps = 25/276 (9%)

Query: 294  LLEPGQASQIKVTFQPLTAVIYEVQATCWYGAGSRQRSSIQLQAVAKCAQLLVSIKHKCP 353
            +++PG   +I +TF P  ++ Y  Q    +      + +++++      ++LV       
Sbjct: 4366 VVKPGNTLEIPITFYPRESINY--QELIPFEINGLSQQTVEIKGKGTKMKILV------- 4416

Query: 354  EDQDAEGFQKLLYFGSVAVGCTSERQIRLHNPSAVNAPFRIEI--SPDELAEDQAFSCPT 411
                 +   +++  G+V  G   +R + + N S     F   I  +  EL E +  +   
Sbjct: 4417 ----LDPANRIVKLGAVLPGQVVKRTVSIMNNSLAQLTFNQSILFTIPELQEPKVLTLAP 4472

Query: 412  AHGIVLPGEKKC-VSVFFHPKTLDTRTVDYCSIMPSGCAS--KTLLKVVGFCRGPAVSLQ 468
             H I L  ++ C + V F PK    R   +   +   C    + L  + G C+   +SL 
Sbjct: 4473 FHNITLKPKEVCKLEVIFAPKK---RVPPFSEEVFMECMGLLRPLFLLSGCCQALEISLD 4529

Query: 469  HYCVNFSWVNLGERSEQPLWIENQSDCTAHFQFAIDCLESVFTIRPAFGTLVGKARMTLH 528
               + F  V    ++ + + + N  D  A F++ I   E  F+I P  G +     ++  
Sbjct: 4530 QEHIPFGPVVYQTQATRRILMMNTGDVGARFKWDIKKFEPHFSISPEEGYITSGMEVSFE 4589

Query: 529  CAFQPTH---PIICFRRVACLIHHQDPLFLDLMGTC 561
              + PT      +C + + C I    PL L L G C
Sbjct: 4590 VTYHPTEVGKESLC-KNILCYIQGGSPLSLTLSGVC 4624



 Score = 48.9 bits (115), Expect = 5e-05
 Identities = 56/234 (23%), Positives = 98/234 (41%), Gaps = 19/234 (8%)

Query: 285  PFQMLPATGLLEPGQASQIKVTFQPLTAVIYEVQATCWYG----------AGSRQRSSIQ 334
            PF + P++G++  G+  + KV F PL    +E    C               ++ RS++ 
Sbjct: 3888 PFSVEPSSGIVPVGKIQKFKVKFSPLDIGDFESNLFCQIPNLPPGEQGPVLVAKGRSTLP 3947

Query: 335  LQAVAKCAQLLVSIKHKCPEDQDAEGFQ-----KLLYFGSVAVGCTSERQIRLHNPSAVN 389
            +          +S   + PE + + G       +++ F +V +G  + R   + NP+   
Sbjct: 3948 ICHFDLKDSDYISGHQRNPELRGSSGGALDPNTRVIEFTTVGIGGKNLRTFTILNPTNST 4007

Query: 390  APFR-IEISPDELAEDQAFSCPTAHGIVLPGEKKCVSVF-FHPKTLDTRTVDYCSIMPSG 447
              F  I    + L    AF+C T  G + P EKK   VF F P  L      +  ++P  
Sbjct: 4008 YSFCWISEEIESLQNPAAFTCLTEKGFIHP-EKKAEIVFQFTPFHLGITESSWTFLIPEH 4066

Query: 448  CASKTLLKVVGFCRGPAVSLQHYCVNFSWVNLGERSEQPLWIENQSDCTAHFQF 501
              +   L +VG    P +SL    +NFS + +G  + + + I N+ +    F F
Sbjct: 4067 NITVPFL-LVGKTTEPLISLNKSHLNFSSLLIGREARETVQIINKEEQGFDFSF 4119



 Score = 39.7 bits (91), Expect = 0.029
 Identities = 40/169 (23%), Positives = 73/169 (43%), Gaps = 20/169 (11%)

Query: 1241 SPKAGSLSPGQEQMVELKYSHL--FIGTDHLPVLFKVSHGREILLNFIGVTVKPEQKYVH 1298
            SP   ++  GQ     L +  L   + TD L ++ K+SHG   + N  G  V P    +H
Sbjct: 4256 SPIDSTVDVGQSVHATLSFQPLKKCVLTD-LELIIKISHGPTFMCNISGCAVSPA---IH 4311

Query: 1299 FTSTTHQFIPIPIGDT-LPP-RQIYELYNGGSVPVTYEVQTDVLSQVQEKNFDHPIFCCL 1356
            F+ T++ F    I    +PP +Q   + N    P++ +      + ++           +
Sbjct: 4312 FSFTSYNFGTCFIYQAGMPPYKQTLVITNKEETPMSIDCLYTNTTHLE-----------V 4360

Query: 1357 NPKGEI-QPGSTARVLWIFSPIEAKTYTVDVPIHILGWNSALIHFQGVG 1404
            N + ++ +PG+T  +   F P E+  Y   +P  I G +   +  +G G
Sbjct: 4361 NSRVDVVKPGNTLEIPITFYPRESINYQELIPFEINGLSQQTVEIKGKG 4409



 Score = 39.3 bits (90), Expect = 0.038
 Identities = 32/130 (24%), Positives = 59/130 (45%), Gaps = 20/130 (15%)

Query: 1717 KFMDQKNSLYLMPILPVPSSSWEDGKGKQPKEDRPEHYPGLGKKEEGEEEKGEEEEEELE 1776
            K +  +  +Y++ +    ++     K K+ +E+R +H   L K++E  +   EEE + L 
Sbjct: 2252 KAIGSREHIYILNMAQDYAAMKAQEKAKKEQEER-KHKGALEKEKERLQNMDEEEYDALT 2310

Query: 1777 EEEE------------EEEETEEEELGKEEIE-------EKEEERDEKEEKVSWAGIGPT 1817
            EEE+            E ++ E+E L KE  E       E+++E DE + +V     GP 
Sbjct: 2311 EEEKLTFDRGIQQALRERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPI 2370

Query: 1818 PQPESQESMQ 1827
             +    +  Q
Sbjct: 2371 KEEPPMKKSQ 2380



 Score = 36.6 bits (83), Expect = 0.24
 Identities = 33/149 (22%), Positives = 64/149 (42%), Gaps = 21/149 (14%)

Query: 286  FQMLPATGLLEPGQASQIKVTFQPLTAVIYEVQATCWYGAGSRQRSSIQLQAVAKCAQLL 345
            F +LP  G+L+P  + QI  TF     +I + +A C    G     +++ +A        
Sbjct: 1329 FDILPLFGVLQPHSSHQISFTFYGHANIIAQAKALCEVEEGPTYEITLKGEA-------- 1380

Query: 346  VSIKHKCPEDQDAEGFQKLLYFGSVAVGCTSERQIRLHNPSAVNAPFRI----EISPDEL 401
             S+ +   + +D       +++G       +ER+I L N   V   F++    + SPD L
Sbjct: 1381 -SLVNYSFDTKD-------IHYGLQLFDHVTEREITLTNMGKVGFEFKVLTDHQSSPDNL 1432

Query: 402  AEDQAFSCPTAHGIVLPGEKKCVSVFFHP 430
                    P + G +   +++ + V++ P
Sbjct: 1433 LPGVPLILPVS-GFISSHQEQVLKVYYLP 1460



 Score = 35.4 bits (80), Expect = 0.54
 Identities = 22/69 (31%), Positives = 34/69 (49%), Gaps = 1/69 (1%)

Query: 1340 LSQVQEKNFDHPIFCCLNPKGEIQPGSTARVLWIFSPIEAKTYTVDVPIHILGWNSAL-I 1398
            L Q   K F + +F     +G++ P S+A +   F+P+EAK Y   +   ILG    L +
Sbjct: 391  LVQGDSKLFFNNVFTVEPLEGDVWPNSSAEITVYFNPLEAKLYQQTIYCDILGREIRLPL 450

Query: 1399 HFQGVGYNP 1407
              +G G  P
Sbjct: 451  RIKGEGMGP 459



 Score = 35.4 bits (80), Expect = 0.54
 Identities = 42/199 (21%), Positives = 78/199 (39%), Gaps = 18/199 (9%)

Query: 282 FSSPFQMLPATGLLEPGQASQIKVTFQPLTAVIYEVQATCWYGAGSRQRSSIQLQAVAKC 341
           F++ F + P  G + P  +++I V F PL A +Y+               +I    + + 
Sbjct: 400 FNNVFTVEPLEGDVWPNSSAEITVYFNPLEAKLYQ--------------QTIYCDILGRE 445

Query: 342 AQLLVSIKHKCPEDQDAEGFQKLLYFGSVAVGCTSERQIRLHNPSAVNAPFRIEISPDEL 401
            +L + IK +    +    F+ LL  G V  G     +  L+N  +++A F   ++P   
Sbjct: 446 IRLPLRIKGEGMGPKIHFNFE-LLDIGKVFTGSAHCYEAILYNKGSIDALF--NMTPPTS 502

Query: 402 AEDQAFSCPTAHGIVLPGEKKCVSVFFHPKTLDTRTVDYCSIMPSGCASKTLLKVVGFCR 461
           A    F      GI+ P   + + + F    L     ++  +  +G      L + G   
Sbjct: 503 ALGACFVFSPKEGIIEPSGVQAIQISFSSTILGNFEEEFL-VNVNGSPEPVKLTIRGCVI 561

Query: 462 GPAVSLQHYCVNFSWVNLG 480
           GP        ++F  V+ G
Sbjct: 562 GPTFHFNVPALHFGDVSFG 580



 Score = 35.4 bits (80), Expect = 0.54
 Identities = 55/235 (23%), Positives = 93/235 (39%), Gaps = 20/235 (8%)

Query: 286 FQMLPATGLLEPGQASQIKVTFQPLTAVIYEVQATCWY-GAGSRQRSSIQLQAVAKCAQL 344
           F + P  G + P   + I+VT    T   YE+       G G       ++ A+   A+ 
Sbjct: 640 FTISPDCGTIRPQGFAAIRVTLCSNTVQKYELALVVDVEGIGE------EVLALLITARC 693

Query: 345 LVSIKHKCPEDQDAEGFQKLLYFGSVAVGCTSERQIRLHNPSAVNAPFRIEISPDELAED 404
           +V   H    + D         FG   +    E+ ++L N   +   + ++    E    
Sbjct: 694 VVPALHLVNTEVD---------FGHCFLKYPYEKTLQLANQDDLPGFYEVQPQVCEEVPT 744

Query: 405 QAFSCPTAHGIVLPGEKKCVSVFFHPK-TLDTRTVDYCSIMPSGCASKTL-LKVVGFCRG 462
             FS PT  G++ P     + +    + T + R+  Y SI  S        LK  G   G
Sbjct: 745 VLFSSPTPSGVISPSSTIHIPLVLETQVTGEHRSTVYISIFGSQDPPLVCHLKSAG--EG 802

Query: 463 PAVSLQHYCVNFSWVNLGERSEQPLWIENQSDCTAHFQFAIDCLESVFTIRPAFG 517
           P + +    V+F  + + + S + L + NQS   A FQ  +   +S++TI P  G
Sbjct: 803 PVIYVHPNQVDFGNIYVLKDSSRILNLCNQSFIPAFFQAHMAHKKSLWTIEPNEG 857



 Score = 34.3 bits (77), Expect = 1.2
 Identities = 34/141 (24%), Positives = 55/141 (39%), Gaps = 28/141 (19%)

Query: 1718 FMDQKNSLYLMPILPVPSSSWEDGKGKQPKEDRPEHYPGLGKKEEGEEEKGEEEEEELEE 1777
            + D+K  + L P           G  + P E   +    LG    G   + + E E LE+
Sbjct: 2472 YWDRKQGVQLPPA----------GMEEAPHEPDDQRQVPLG----GRRGRKDRERERLEK 2517

Query: 1778 EEEEEEETEEEELGKEEIE-------------EKEEERDEKEEKVSWAGIGPTPQPESQE 1824
            E  E+E  E E+  +E +E             E EE+ + K+EK           P+  E
Sbjct: 2518 ERTEKERLEREKAERERLEKLRALEERSDWEGEGEEDHEGKKEKDLGVPFLDIQTPDF-E 2576

Query: 1825 SMQWQWQQQLNVMVKEEQEQD 1845
             + W+   + + + K EQ  D
Sbjct: 2577 GLSWKQALESDKLPKGEQILD 2597



 Score = 32.3 bits (72), Expect = 4.6
 Identities = 22/67 (32%), Positives = 34/67 (50%), Gaps = 4/67 (5%)

Query: 1238 FSISPKAGSLSPGQEQMVELKYSHLFIGTDHL--PVLFKVSHGREILLNFIGVTVKPE-- 1293
            FSISP+ G ++ G E   E+ Y    +G + L   +L  +  G  + L   GV V P   
Sbjct: 4571 FSISPEEGYITSGMEVSFEVTYHPTEVGKESLCKNILCYIQGGSPLSLTLSGVCVGPPAV 4630

Query: 1294 QKYVHFT 1300
            ++ V+FT
Sbjct: 4631 KEVVNFT 4637



 Score = 32.0 bits (71), Expect = 6.0
 Identities = 23/98 (23%), Positives = 44/98 (44%), Gaps = 5/98 (5%)

Query: 1444 HISLGNIPVQSKCSRLLFLNNISKNEEIAFSWQPSPLDFGEVSVSPMIGVVAPEETVPFV 1503
            HI  G+  +    +    + N S+   I F W  S      ++ SP +G + P      V
Sbjct: 3654 HIQFGDCHIGHSYNASFTVTNHSQVNLIRFEWPVS----ATIAFSPQMGHLHPGCAKDIV 3709

Query: 1504 VTLRASVHASFYSADLVCKLYSQQLMRQYHKELQEWKD 1541
            VT+++ V  +  +  + CKL S+ + +    ++ +W D
Sbjct: 3710 VTMKSDVPINLKNMRIRCKL-SRIMFQLPADQVPDWDD 3746


>gi|46361983 hydrocephalus inducing isoform b [Homo sapiens]
          Length = 1017

 Score = 60.8 bits (146), Expect = 1e-08
 Identities = 53/242 (21%), Positives = 99/242 (40%), Gaps = 19/242 (7%)

Query: 166 LVLKNRSLKLQKMKYRPPKTKFFFTVIPQPIF--LSPGITLTLPIVFRPLEAKEYMDQLW 223
           L+L+N     + +K     + +F  + P+ I   ++PG+     I+F P E K+Y   L 
Sbjct: 120 LILRNNDKIPRLVKVVEESSPYFKVISPKDIGHKVAPGVPSIFRILFTPEENKDYAHTLT 179

Query: 224 FEKAEGMFCVGLRATLPCHRLICRPPSLQLPMCAVGDTTEAFFCLDNVGDLPTFFTWEFS 283
                  F V ++A      ++  P  L    C V  +T+    + N+G+    F  +  
Sbjct: 180 CVTEREKFIVPIKAR-GARAILDFPDKLNFSTCPVKYSTQKILLVRNIGNKNAVFHIKTC 238

Query: 284 SPFQMLPATGLLEPGQASQIKVTFQPLTAVIYEVQATCWYGAGSRQRSSIQLQAVAKCAQ 343
            PF + PA G L  G++ Q++V F+P +   +  +    Y  G +   S+   A+     
Sbjct: 239 RPFSIEPAIGTLNVGESMQLEVEFEPQSVGDHSGRLIVCYDTGEKVFVSLYGAAI----- 293

Query: 344 LLVSIKHKCPEDQDAEGFQKLLYFGSVAVGCTSERQIRLHNPSAVNAPFRIEISPDELAE 403
                      D +    +  L      +   ++R I +HN S + A F  ++   +  E
Sbjct: 294 -----------DMNIRLDKNSLTIEKTYISLANQRTITIHNRSNIIAHFLWKVFATQQEE 342

Query: 404 DQ 405
           D+
Sbjct: 343 DR 344



 Score = 35.4 bits (80), Expect = 0.54
 Identities = 22/69 (31%), Positives = 34/69 (49%), Gaps = 1/69 (1%)

Query: 1340 LSQVQEKNFDHPIFCCLNPKGEIQPGSTARVLWIFSPIEAKTYTVDVPIHILGWNSAL-I 1398
            L Q   K F + +F     +G++ P S+A +   F+P+EAK Y   +   ILG    L +
Sbjct: 391  LVQGDSKLFFNNVFTVEPLEGDVWPNSSAEITVYFNPLEAKLYQQTIYCDILGREIRLPL 450

Query: 1399 HFQGVGYNP 1407
              +G G  P
Sbjct: 451  RIKGEGMGP 459



 Score = 35.4 bits (80), Expect = 0.54
 Identities = 42/199 (21%), Positives = 78/199 (39%), Gaps = 18/199 (9%)

Query: 282 FSSPFQMLPATGLLEPGQASQIKVTFQPLTAVIYEVQATCWYGAGSRQRSSIQLQAVAKC 341
           F++ F + P  G + P  +++I V F PL A +Y+               +I    + + 
Sbjct: 400 FNNVFTVEPLEGDVWPNSSAEITVYFNPLEAKLYQ--------------QTIYCDILGRE 445

Query: 342 AQLLVSIKHKCPEDQDAEGFQKLLYFGSVAVGCTSERQIRLHNPSAVNAPFRIEISPDEL 401
            +L + IK +    +    F+ LL  G V  G     +  L+N  +++A F   ++P   
Sbjct: 446 IRLPLRIKGEGMGPKIHFNFE-LLDIGKVFTGSAHCYEAILYNKGSIDALF--NMTPPTS 502

Query: 402 AEDQAFSCPTAHGIVLPGEKKCVSVFFHPKTLDTRTVDYCSIMPSGCASKTLLKVVGFCR 461
           A    F      GI+ P   + + + F    L     ++  +  +G      L + G   
Sbjct: 503 ALGACFVFSPKEGIIEPSGVQAIQISFSSTILGNFEEEFL-VNVNGSPEPVKLTIRGCVI 561

Query: 462 GPAVSLQHYCVNFSWVNLG 480
           GP        ++F  V+ G
Sbjct: 562 GPTFHFNVPALHFGDVSFG 580



 Score = 35.4 bits (80), Expect = 0.54
 Identities = 55/235 (23%), Positives = 93/235 (39%), Gaps = 20/235 (8%)

Query: 286 FQMLPATGLLEPGQASQIKVTFQPLTAVIYEVQATCWY-GAGSRQRSSIQLQAVAKCAQL 344
           F + P  G + P   + I+VT    T   YE+       G G       ++ A+   A+ 
Sbjct: 640 FTISPDCGTIRPQGFAAIRVTLCSNTVQKYELALVVDVEGIGE------EVLALLITARC 693

Query: 345 LVSIKHKCPEDQDAEGFQKLLYFGSVAVGCTSERQIRLHNPSAVNAPFRIEISPDELAED 404
           +V   H    + D         FG   +    E+ ++L N   +   + ++    E    
Sbjct: 694 VVPALHLVNTEVD---------FGHCFLKYPYEKTLQLANQDDLPGFYEVQPQVCEEVPT 744

Query: 405 QAFSCPTAHGIVLPGEKKCVSVFFHPK-TLDTRTVDYCSIMPSGCASKTL-LKVVGFCRG 462
             FS PT  G++ P     + +    + T + R+  Y SI  S        LK  G   G
Sbjct: 745 VLFSSPTPSGVISPSSTIHIPLVLETQVTGEHRSTVYISIFGSQDPPLVCHLKSAG--EG 802

Query: 463 PAVSLQHYCVNFSWVNLGERSEQPLWIENQSDCTAHFQFAIDCLESVFTIRPAFG 517
           P + +    V+F  + + + S + L + NQS   A FQ  +   +S++TI P  G
Sbjct: 803 PVIYVHPNQVDFGNIYVLKDSSRILNLCNQSFIPAFFQAHMAHKKSLWTIEPNEG 857


>gi|239745093 PREDICTED: hypothetical protein XP_002343359 [Homo
            sapiens]
          Length = 142

 Score = 59.7 bits (143), Expect = 3e-08
 Identities = 34/62 (54%), Positives = 39/62 (62%)

Query: 1744 KQPKEDRPEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERD 1803
            K+ +E R E     GK+ E EEEK EEEEEE EEEEEEEEE EEE        E+E E +
Sbjct: 76   KRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETE 135

Query: 1804 EK 1805
            EK
Sbjct: 136  EK 137



 Score = 50.4 bits (119), Expect = 2e-05
 Identities = 28/66 (42%), Positives = 44/66 (66%), Gaps = 2/66 (3%)

Query: 1759 KKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEKVSWAGIGPTP 1818
            ++E+  EEK  EE+    +  E+EEE EEEE  +EE EE+EEE +E+EE+VS++      
Sbjct: 73   REEKRREEKRREEKRREGKRREKEEEKEEEE--EEEEEEEEEEEEEEEEEVSFSLATRER 130

Query: 1819 QPESQE 1824
            + E++E
Sbjct: 131  ETETEE 136



 Score = 48.9 bits (115), Expect = 5e-05
 Identities = 28/64 (43%), Positives = 38/64 (59%)

Query: 1739 EDGKGKQPKEDRPEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEK 1798
            E  + ++ +E++        K+EE EEE+ EEEEEE EEEEEEEEE       +E   E 
Sbjct: 75   EKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETET 134

Query: 1799 EEER 1802
            EE+R
Sbjct: 135  EEKR 138



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 29/95 (30%), Positives = 45/95 (47%), Gaps = 8/95 (8%)

Query: 1722 KNSLYLMPILPVPSSSWEDGKG-----KQPKEDRP---EHYPGLGKKEEGEEEKGEEEEE 1773
            +N   L+   P P S  E+  G        KE+ P       G   ++    E+   EE+
Sbjct: 17   ENDRILLSTFPYPHSKRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEK 76

Query: 1774 ELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEK 1808
              EE+  EE+  E +   KEE +E+EEE +E+EE+
Sbjct: 77   RREEKRREEKRREGKRREKEEEKEEEEEEEEEEEE 111



 Score = 35.0 bits (79), Expect = 0.71
 Identities = 19/51 (37%), Positives = 29/51 (56%)

Query: 1740 DGKGKQPKEDRPEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETEEEEL 1790
            +GK ++ +E++ E      ++EE EEE+ EEE        E E ETEE+ L
Sbjct: 89   EGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKRL 139


>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
          Length = 1184

 Score = 58.9 bits (141), Expect = 5e-08
 Identities = 30/69 (43%), Positives = 47/69 (68%), Gaps = 4/69 (5%)

Query: 1739 EDGKGKQPKEDRPEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEK 1798
            E+ +G++  ED  E     G ++E +EE   EEEEE+EEE+E+++E  E+   +EE EE+
Sbjct: 103  EEDEGEEYSEDNDEP----GDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEE 158

Query: 1799 EEERDEKEE 1807
            EEE +E+EE
Sbjct: 159  EEEEEEEEE 167



 Score = 52.0 bits (123), Expect = 6e-06
 Identities = 32/102 (31%), Positives = 56/102 (54%), Gaps = 14/102 (13%)

Query: 1745 QPKEDRPEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDE 1804
            + +ED  E Y      E G+E++ E+EE + EEEEE EEE E+++   E++E++EEE +E
Sbjct: 101  EKEEDEGEEYSE-DNDEPGDEDE-EDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEE 158

Query: 1805 KEEKVSWAGIGPTPQPESQESMQWQWQQQLNVMVKEEQEQDE 1846
            +EE+            E +E  +       N  + ++ E+D+
Sbjct: 159  EEEE------------EEEEENEDHQMNCHNTRIMQDTEKDD 188



 Score = 51.2 bits (121), Expect = 1e-05
 Identities = 31/110 (28%), Positives = 59/110 (53%), Gaps = 11/110 (10%)

Query: 1744 KQPKEDRPEHYPGLGKKE-----EGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEK 1798
            KQP+E  P+  P   K +     E ++  G E+ +E EE+E EE   + +E G E+ E++
Sbjct: 66   KQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDE 125

Query: 1799 EEERDEKEEKVSWAGIGPTPQPESQESMQWQWQQQLNVMVKEEQEQDEKE 1848
            E +R+E+EE      I    + + ++    + +++     +EE+E++E E
Sbjct: 126  EGDREEEEE------IEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENE 169



 Score = 40.4 bits (93), Expect = 0.017
 Identities = 26/72 (36%), Positives = 38/72 (52%), Gaps = 3/72 (4%)

Query: 1739 EDGKGKQPKEDRPEHYPGLGKKEEGE--EEKGEEEEEELEEEEEEEEETEEEELGKEEIE 1796
            ED +G + +E+  E        E+GE  E++ EEEEEE EEEEEEE E  +       I 
Sbjct: 123  EDEEGDREEEEEIEEEDE-DDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIM 181

Query: 1797 EKEEERDEKEEK 1808
            +  E+ D   ++
Sbjct: 182  QDTEKDDNNNDE 193


>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
            sapiens]
          Length = 1152

 Score = 58.5 bits (140), Expect = 6e-08
 Identities = 48/125 (38%), Positives = 69/125 (55%), Gaps = 17/125 (13%)

Query: 1739 EDGKGKQPKED-----RPEHYPGLGKKE---EGEEEKGEEEEEELE---EEEEEEEETEE 1787
            EDG+G+  +E+       E   G G++E   EGEE +GE EEEE E   EEEE EEE EE
Sbjct: 942  EDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEE 1001

Query: 1788 EELGKEEIE---EKEEERDEKEEKVSWAGIGPTPQPESQ---ESMQWQWQQQLNVMVKEE 1841
            E  G+EE E   E+EEE + + E     G G   + E +   E  + + + + N   +EE
Sbjct: 1002 EGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREE 1061

Query: 1842 QEQDE 1846
            +E++E
Sbjct: 1062 EEEEE 1066



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 41/113 (36%), Positives = 63/113 (55%), Gaps = 5/113 (4%)

Query: 1740 DGKGKQPKE----DRPEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEI 1795
            +G+G++ +E    +  E   G G++EE EEE+GE EEEE E EEEE E  EEE  GK E 
Sbjct: 802  EGRGEEKEEGGEVEGGEVEEGKGEREE-EEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEE 860

Query: 1796 EEKEEERDEKEEKVSWAGIGPTPQPESQESMQWQWQQQLNVMVKEEQEQDEKE 1848
            E +E E +E+ E+    G     + E +E  + + +++      EE+ + E E
Sbjct: 861  EGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGE 913



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 44/117 (37%), Positives = 64/117 (54%), Gaps = 11/117 (9%)

Query: 1739 EDGKGKQPKED---RPEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETEEEE---LGK 1792
            E+G+G++  E+     E   G G+ EE  E +GEEEE E E EEE E E EEEE    G+
Sbjct: 863  EEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGE 922

Query: 1793 EEIEEKEEERDEKEEKVSWAGIGPTPQPESQESM-QWQWQQQLNVMVKEEQEQDEKE 1848
            EE EE E E +E+E +    G G   + E +E   +W+ +++      EE+ + E E
Sbjct: 923  EEGEEGEGEGEEEEGE----GEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGE 975



 Score = 55.8 bits (133), Expect = 4e-07
 Identities = 46/127 (36%), Positives = 63/127 (49%), Gaps = 18/127 (14%)

Query: 1740 DGKGKQPKEDRPEHYPGLGKKEE--GEEEKGEEEEEELEEEEEEEEETEEEELG------ 1791
            DG+ ++ KE    H     ++ E  GEEE GE EEEE + EEEEE+E E +E G      
Sbjct: 706  DGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVE 765

Query: 1792 ----KEEIEEKEEERDEKEEKVSWAGIGPTPQPESQESMQWQWQQQLNV------MVKEE 1841
                KEE E K+EER  KEEK    G     + E  E    + ++   V        K E
Sbjct: 766  GEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGE 825

Query: 1842 QEQDEKE 1848
            +E++E+E
Sbjct: 826  REEEEEE 832



 Score = 54.7 bits (130), Expect = 9e-07
 Identities = 44/114 (38%), Positives = 63/114 (55%), Gaps = 8/114 (7%)

Query: 1739 EDGKGKQPKEDRPEHYPGLGKKEEGEEEKGEEEEEELE---EEEEEEEETEEEELGKEEI 1795
            E+GKG++ +E+  E   G  ++ EGEEE+GE EEEE E   EEE EE E EEE  G+E  
Sbjct: 820  EEGKGEREEEE--EEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEE--GEEGE 875

Query: 1796 EEKEEERDEKEEKVSWAGIGPTPQPESQESMQWQWQ-QQLNVMVKEEQEQDEKE 1848
             E EEE  E E +    G G   + E +   + + + ++     K E+E +E E
Sbjct: 876  GEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGE 929



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 38/108 (35%), Positives = 57/108 (52%), Gaps = 9/108 (8%)

Query: 1739 EDGKGKQPKEDRPEHYPGLGKKEEGEEE------KGEEEEEELEEEEEEEEETEEEELGK 1792
            E+ +G+   E   E   G G++EEGEEE      +GE EE     EEEEEEE + +E G+
Sbjct: 1015 EEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGE 1074

Query: 1793 EEIEEKEEERDEKEEKVSWA---GIGPTPQPESQESMQWQWQQQLNVM 1837
            EE E ++ E  +K  K+  +   G   T Q +S  + Q   ++Q + M
Sbjct: 1075 EENERQDGEEYKKVSKIKGSVKYGKHKTYQKKSVTNTQGNGKEQRSKM 1122



 Score = 53.5 bits (127), Expect = 2e-06
 Identities = 43/110 (39%), Positives = 62/110 (56%), Gaps = 11/110 (10%)

Query: 1739 EDGKGKQPKEDRPEHYPGLGKKEEGEEE----KGEEEEEELE-EEEEEEEETEEEELGKE 1793
            E+G+GK   E+  E   G G++EEGE E    +GE EEEE E E EEEE E E EE G+ 
Sbjct: 915  EEGEGKG--EEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEG 972

Query: 1794 EIEEKEEERDEKEEKVSWAGIGPTPQPESQESMQWQWQQQLNVMVKEEQE 1843
            E EE E E +E+E +    G G   + E +   + + +++     +EE+E
Sbjct: 973  EGEEGEGEGEEEEGE----GEGEEEEGEEEGEEEGEGEEEGEGEGEEEEE 1018



 Score = 53.1 bits (126), Expect = 3e-06
 Identities = 39/116 (33%), Positives = 63/116 (54%), Gaps = 7/116 (6%)

Query: 1740 DGKGKQPKEDRPEHYPGLGKKEEGE----EEKGEEEEEEL---EEEEEEEEETEEEELGK 1792
            +G+G++  E   E   G G++EEGE    EE+GEEE EE    EEE E E E EEE   +
Sbjct: 963  EGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVE 1022

Query: 1793 EEIEEKEEERDEKEEKVSWAGIGPTPQPESQESMQWQWQQQLNVMVKEEQEQDEKE 1848
             E+E +E E + +EE+    G     + E +E+ + + +++      +E  ++E E
Sbjct: 1023 GEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENE 1078



 Score = 52.4 bits (124), Expect = 4e-06
 Identities = 35/109 (32%), Positives = 57/109 (52%)

Query: 1740 DGKGKQPKEDRPEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKE 1799
            +G+G++  E   E   G G+ EE  E +GEEEE E + EEE EE   E E  + E E ++
Sbjct: 884  EGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGED 943

Query: 1800 EERDEKEEKVSWAGIGPTPQPESQESMQWQWQQQLNVMVKEEQEQDEKE 1848
             E + +EE+  W G     + E +E  + + ++      +EE E + +E
Sbjct: 944  GEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEE 992



 Score = 52.0 bits (123), Expect = 6e-06
 Identities = 44/114 (38%), Positives = 62/114 (54%), Gaps = 12/114 (10%)

Query: 1739 EDGKGKQPKED---RPEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETEE-EELGKEE 1794
            E+G+G+  +E+     E   G G++EEGE E GEEEE E E EEE E E EE E  G+EE
Sbjct: 926  EEGEGEGEEEEGEGEGEDGEGEGEEEEGEWE-GEEEEGEGEGEEEGEGEGEEGEGEGEEE 984

Query: 1795 IEEKEEERDEKEEKVSWAGIGPTPQPESQESMQWQWQQQLNVMVKEEQEQDEKE 1848
              E E E +E EE+    G       E +E  + + +++    V+ E E +E E
Sbjct: 985  EGEGEGEEEEGEEEGEEEG-------EGEEEGEGEGEEEEEGEVEGEVEGEEGE 1031



 Score = 52.0 bits (123), Expect = 6e-06
 Identities = 43/122 (35%), Positives = 67/122 (54%), Gaps = 12/122 (9%)

Query: 1740 DGKGKQPK-EDRPEHYPGLGKKEEGEEE-----KGEEE-EEELEEEEEEEEETE-EEELG 1791
            +G+G++ + E   E   G G++EEGEEE     +GEEE E E EEEEE E E E E E G
Sbjct: 971  EGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEG 1030

Query: 1792 KEEIEEKEEERDEKEEKVSWAGIGPTPQPESQESMQWQWQQQLNVMVKEEQEQDEKEAIR 1851
            + E EE+E E + +E +    G       E +E  + ++Q+      +EE E+ + E  +
Sbjct: 1031 EGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQE----TGEEENERQDGEEYK 1086

Query: 1852 RL 1853
            ++
Sbjct: 1087 KV 1088



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 38/120 (31%), Positives = 63/120 (52%), Gaps = 11/120 (9%)

Query: 1738 WEDG---KGKQPKEDRPEHYPGLGKKEEGEEEK-----GEEEEE-ELEEEEEEEEETEEE 1788
            W+D    KG++ K       PG G+KE  E+E+     GEE+E+ E E+  ++E   E E
Sbjct: 669  WQDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEME 728

Query: 1789 ELGKEEIEEKEEERDEKEEKVSWAGIGPTPQPESQESMQWQWQQQLNVMVKEEQEQDEKE 1848
            E G+EE  E EEE  ++EE+    G G   +    E ++ + +++     KEE+   E++
Sbjct: 729  EGGEEEHGEGEEEEGDREEEEEKEGEG--KEEGEGEEVEGEREKEEGERKKEERAGKEEK 786



 Score = 48.1 bits (113), Expect = 8e-05
 Identities = 39/95 (41%), Positives = 53/95 (55%), Gaps = 21/95 (22%)

Query: 1739 EDGKGKQPKEDRPEHYPGLGKKEEGEEE--KGEEEEEELE---EEEEEEEETE----EEE 1789
            E  +G++ KE+R       GK+E+GEEE  +GE EEEE E   EE+EE  E E    EE 
Sbjct: 769  EKEEGERKKEERA------GKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEG 822

Query: 1790 LGKEEIEEKEEERDEKEEKVSWAGIGPTPQPESQE 1824
             G+ E EE+E E +E+E      G G   + E +E
Sbjct: 823  KGEREEEEEEGEGEEEE------GEGEEEEGEGEE 851



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 48/139 (34%), Positives = 70/139 (50%), Gaps = 33/139 (23%)

Query: 1739 EDGKGKQPKEDRPEHYP--GLGKKE-EGEE-------EKGEEEEEELEEEEE-------- 1780
            E G+G++ + DR E     G GK+E EGEE       E+GE ++EE   +EE        
Sbjct: 734  EHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQ 793

Query: 1781 ---EEEET----EEEELGKE----EIEEKEEERDEKEEKVSWAGIGPTPQPESQESMQWQ 1829
               EEEET    EE+E G E    E+EE + ER+E+EE+    G G   + E +E     
Sbjct: 794  GEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEE----GEGEEEEGEGEEEEGEG 849

Query: 1830 WQQQLNVMVKEEQEQDEKE 1848
             +++     +EE E+ E E
Sbjct: 850  EEEEGEGKGEEEGEEGEGE 868



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 37/114 (32%), Positives = 57/114 (50%), Gaps = 14/114 (12%)

Query: 1739 EDGKGKQPKEDRPEHYPGLGKKEEGEEEKGEEEEE-----ELE--------EEEEEEEET 1785
            E+G+G+  +E+  E     G+ EE  E +GEEEEE     E+E        EEEE EEE 
Sbjct: 984  EEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEG 1043

Query: 1786 EEEELGKEEIEEKEEERDEKEEKVSWAGIGPTPQPESQESMQWQWQQQLNVMVK 1839
            EE E   E  E +    +E+EE+  +   G   + E Q+  +++   ++   VK
Sbjct: 1044 EEREKEGEGEENRRNREEEEEEEGKYQETG-EEENERQDGEEYKKVSKIKGSVK 1096



 Score = 40.8 bits (94), Expect = 0.013
 Identities = 59/227 (25%), Positives = 93/227 (40%), Gaps = 48/227 (21%)

Query: 1653 SETSEEKSPNKWGPVSKQKKQLLVDILTTIIRGLLEDKNFHEAVDQSLVEQVPYFRQ--- 1709
            S  S EKS  K  PV KQKKQ  +  LT     L E+ +  E  + S +++    +Q   
Sbjct: 507  SLNSNEKSL-KLSPVQKQKKQQTIGELTQDT-ALTENDDSDEYEEMSEMKEGKACKQHVS 564

Query: 1710 ---FWNEQSTK---FMDQKNSLYLMPILPVPSSSWEDGKGKQPKEDRPEHYPGLGKKEEG 1763
               F  + +T    F D++  +      P      ED KG   +E   E      K   G
Sbjct: 565  QGIFMTQPATTIEAFSDEEVEI------PEEKEGAEDSKGNGIEEQEVEANEENVKVHGG 618

Query: 1764 EEEKGEEEEEELEEEEEEEE-------------------ETEEEELGKEEIEEKEEERDE 1804
             +EK E   ++L ++ E  E                     EE   G E  +++E E+ E
Sbjct: 619  RKEKTEILSDDLTDKAEVSEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGE 678

Query: 1805 KEEKVSWAGIGPTPQP---ESQESMQWQWQQQLNVMVKEEQEQDEKE 1848
            K++     G G   +P   E + + + +W+++      EEQEQ E+E
Sbjct: 679  KDK-----GRGEMERPGEGEKELAEKEEWKKRDG----EEQEQKERE 716


>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
            protein 6 [Homo sapiens]
          Length = 724

 Score = 58.2 bits (139), Expect = 8e-08
 Identities = 33/96 (34%), Positives = 59/96 (61%), Gaps = 14/96 (14%)

Query: 1761 EEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEKVSWAGIGPTPQP 1820
            +E EE+ GE+EE+  E+EE+ +E+ E+    +E+I E+E++  E+EEK+           
Sbjct: 609  QEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIR---------- 658

Query: 1821 ESQESMQWQ----WQQQLNVMVKEEQEQDEKEAIRR 1852
            E +E MQ Q    W+Q+  +  +EE+ Q+++E +RR
Sbjct: 659  EQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRR 694



 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 27/87 (31%), Positives = 53/87 (60%), Gaps = 6/87 (6%)

Query: 1765 EEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEKVSWAGIGPTPQPESQE 1824
            EEK +E+EE++ E+EE+  E EE+   +EE+  ++EE+  ++E++ W       +   QE
Sbjct: 374  EEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWE---KEEKMRRQE 430

Query: 1825 SMQWQWQQQLNVMVKEEQEQDEKEAIR 1851
             M W+ ++++  +   E++  E+E IR
Sbjct: 431  EMMWEKEEKIREL---EEKMHEQEKIR 454



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 34/125 (27%), Positives = 66/125 (52%), Gaps = 3/125 (2%)

Query: 1739 EDGKGKQPKEDRPEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEK 1798
            ++ K ++ +E        + ++E+  EE+  +E+EE+  +EE+  E EE    KE+I E+
Sbjct: 489  QEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQ 548

Query: 1799 EEERDEKEEKVSWAGIGPTPQPES--QESMQWQWQQQLNVMVKEEQEQDEKEAIRRLPAF 1856
            EE+  ++EEK+ W         E   +E  +  W+Q+  +  +EE+ ++++E IR     
Sbjct: 549  EEKIRKQEEKM-WRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEM 607

Query: 1857 ANLQE 1861
               QE
Sbjct: 608  TQEQE 612



 Score = 49.3 bits (116), Expect = 4e-05
 Identities = 30/102 (29%), Positives = 58/102 (56%), Gaps = 5/102 (4%)

Query: 1764 EEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEKVSWAGIGPTPQPESQ 1823
            +EEK   +EE+++E EE+ +E EE+   +EE   ++EE+  ++E++ W       +   Q
Sbjct: 359  QEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWE---KEEKMRRQ 415

Query: 1824 ESMQWQWQQQLNVMVKEEQEQDEKEAIRRLPAFANLQEALLE 1865
            E M W+ ++++    +EE   +++E IR L    + QE + E
Sbjct: 416  EEMMWEKEEKMR--RQEEMMWEKEEKIRELEEKMHEQEKIRE 455



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 30/95 (31%), Positives = 57/95 (60%), Gaps = 8/95 (8%)

Query: 1759 KKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEE-IEEKEEERDEKEEKVSWAGIGPT 1817
            +K + +EEK   +EE++ E+E++  E EE+   +EE ++E+EE+  E+EEK+        
Sbjct: 627  EKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQ---EE 683

Query: 1818 PQPESQESMQWQ----WQQQLNVMVKEEQEQDEKE 1848
               E +E M+ Q    W+Q++ +  +EE+ Q+ +E
Sbjct: 684  KMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQE 718



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 34/108 (31%), Positives = 60/108 (55%), Gaps = 7/108 (6%)

Query: 1759 KKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEE-IEEKEEERDEKEEKVSWAGIGPT 1817
            +K   +EEK  E+EE++  +EE+  E EE+   +EE I E+EE   E+EEK+   G    
Sbjct: 564  EKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKM---GEQEE 620

Query: 1818 PQPESQESMQWQWQQQLNVMVKEEQEQDEKEAIRRLPAFANLQEALLE 1865
               E +E MQ   +Q+  +  +EE+ +++++ IR        QE +++
Sbjct: 621  KMCEQEEKMQ---EQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQ 665



 Score = 45.8 bits (107), Expect = 4e-04
 Identities = 35/123 (28%), Positives = 69/123 (56%), Gaps = 9/123 (7%)

Query: 1738 WE-DGKGKQPKEDRPEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEE-TEEEELGKEEI 1795
            WE + K ++ +E   E    + ++EE   EK EE+  ELEE+  E+E+  E+EE  +EE 
Sbjct: 406  WEKEEKMRRQEEMMWEKEEKMRRQEEMMWEK-EEKIRELEEKMHEQEKIREQEEKRQEEE 464

Query: 1796 EEKEEERDEKEEKVSWAGIGPTPQPE----SQESMQWQWQQQLNVM--VKEEQEQDEKEA 1849
            + +E+E+ +++E   W       + E     QE   W+ +++++    ++EE+++ E+E 
Sbjct: 465  KIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEE 524

Query: 1850 IRR 1852
            + R
Sbjct: 525  MWR 527



 Score = 45.8 bits (107), Expect = 4e-04
 Identities = 29/98 (29%), Positives = 55/98 (56%), Gaps = 14/98 (14%)

Query: 1764 EEEKGEEEEEELEEEEE-----EEEETEEEELGKEEIEEKEEERDEKEEKVS-----WAG 1813
            +EEK  E+EE++ E+EE     EE+  E+E++ +EE  +++EE   +EEK+      W  
Sbjct: 482  QEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQ 541

Query: 1814 IGPTPQPE----SQESMQWQWQQQLNVMVKEEQEQDEK 1847
                 + E     QE   W+ +++++   ++ +EQ+EK
Sbjct: 542  KEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEK 579



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 24/90 (26%), Positives = 51/90 (56%), Gaps = 6/90 (6%)

Query: 1759 KKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEKVSWAGIGPTP 1818
            +K   +EEK  E+EE++  +EE   E EE+   +EE+  ++EE+  ++E++ W       
Sbjct: 382  EKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMW------E 435

Query: 1819 QPESQESMQWQWQQQLNVMVKEEQEQDEKE 1848
            + E    ++ +  +Q  +  +EE+ Q+E++
Sbjct: 436  KEEKIRELEEKMHEQEKIREQEEKRQEEEK 465



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 36/113 (31%), Positives = 59/113 (52%), Gaps = 14/113 (12%)

Query: 1759 KKEEGEEEKGEEEEEELEEEE---EEEE---ETEEEELGKEEIEEKEEERDEKEEKVSWA 1812
            K    EE   E+EE+   +EE   E+EE   E EE+   +E+I E+EE+R E EEK+   
Sbjct: 411  KMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQE-EEKI--- 466

Query: 1813 GIGPTPQPESQESMQWQWQQQLNVMVKEEQEQDEKEAIRRLPAFANLQEALLE 1865
                  Q + QE     W+Q+  +  +EE+ ++++E + R     + QE + E
Sbjct: 467  ----REQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIRE 515



 Score = 41.6 bits (96), Expect = 0.008
 Identities = 40/176 (22%), Positives = 79/176 (44%), Gaps = 23/176 (13%)

Query: 1713 EQSTKFMDQKNSLYLMPILPVPSSSWEDGKGKQPKEDRPEHYPGLGKKEE--GEEEKGEE 1770
            EQ  K  +Q+  ++             + + +Q +E+       + ++EE   ++EK  E
Sbjct: 488  EQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHE 547

Query: 1771 EEEELEEEEE-----------EEEETEEEELGKEEIEEKEEERDEK----EEKVSWAGIG 1815
            +EE++ ++EE           +EE+  E+E      EEK  E++EK    EEK+      
Sbjct: 548  QEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIR----- 602

Query: 1816 PTPQPESQESMQWQWQQQLNVMVKEEQEQDEKEAIRRLPAFANLQEALLENMIQNI 1871
               +  +QE  +   +Q+  +  +EE+ Q+++E +RR       QE  +    + I
Sbjct: 603  -EQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKI 657



 Score = 40.4 bits (93), Expect = 0.017
 Identities = 39/168 (23%), Positives = 78/168 (46%), Gaps = 29/168 (17%)

Query: 1698 QSLVEQVPYFRQFWNEQSTKFMDQKNSLYLMPILPVPSSSWEDGKGKQPKEDRPEHYPGL 1757
            Q+ VE+   + +   +Q  K   Q+  +            WE+ K ++ +E   E    +
Sbjct: 343  QAQVEENELWNRLNQQQEEKMWRQEEKI----------QEWEE-KIQEQEEKIREQEEKI 391

Query: 1758 GKKEEG---EEEKGEEEEEELEEEEEEEEETEEEELGKEEI----EEKEEE--------- 1801
             ++EE    +EE   E+EE++  +EE   E EE+   +EE+    EEK  E         
Sbjct: 392  REQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQE 451

Query: 1802 --RDEKEEKVSWAGIGPTPQPESQESMQWQWQQQLNVMVKEEQEQDEK 1847
              R+++E++     I    + + QE+  W+ ++++    ++ +EQ+EK
Sbjct: 452  KIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEK 499



 Score = 35.0 bits (79), Expect = 0.71
 Identities = 41/181 (22%), Positives = 81/181 (44%), Gaps = 16/181 (8%)

Query: 1639 LHRELPKRKAPREESETSEEKSPNKWGPVSKQKKQLL-----VDILTTIIRGLLEDKNFH 1693
            +H +  K +   E+    EEK  ++   + +Q++++      +      IR   E     
Sbjct: 545  IHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQ 604

Query: 1694 EAVDQSLVEQVPYFRQFWNEQSTKFMDQKNSLYLMPILPVPSSSWEDGKGKQPKEDRPEH 1753
            E + Q   E++    +   EQ  K  +Q+  +             ++ K ++ +E   E 
Sbjct: 605  EEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQE----EKIREQEKKIREQEEKIREQ 660

Query: 1754 YPGLGKKEEG---EEEKGEEEEEELEEEEE----EEEETEEEELGKEEIEEKEEERDEKE 1806
               + ++EE    +EEK  E+EE+++E+EE    +EE+  E+E+   + EEK +E  E  
Sbjct: 661  EEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHL 720

Query: 1807 E 1807
            E
Sbjct: 721  E 721


>gi|4506411 Ran GTPase activating protein 1 [Homo sapiens]
          Length = 587

 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 29/51 (56%), Positives = 40/51 (78%), Gaps = 2/51 (3%)

Query: 1760 KEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEKVS 1810
            ++E EEE+GEEEEEE EEEEEE+EE EEEE  +EE EE+ ++R + E+  +
Sbjct: 361  EDEEEEEEGEEEEEEAEEEEEEDEEEEEEE--EEEEEEEPQQRGQGEKSAT 409



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 24/42 (57%), Positives = 33/42 (78%)

Query: 1765 EEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKE 1806
            +++ EEEEEE EEEEEE EE EEE+  +EE EE+EEE + ++
Sbjct: 359  DDEDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQ 400



 Score = 49.3 bits (116), Expect = 4e-05
 Identities = 26/50 (52%), Positives = 33/50 (66%)

Query: 1769 EEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEKVSWAGIGPTP 1818
            E+EEEE E EEEEEE  EEEE  +EE EE+EEE +E+ ++        TP
Sbjct: 361  EDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQRGQGEKSATP 410



 Score = 48.9 bits (115), Expect = 5e-05
 Identities = 24/46 (52%), Positives = 32/46 (69%)

Query: 1748 EDRPEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKE 1793
            ED  E   G  ++EE EEE+ E+EEEE EEEEEEEEE ++   G++
Sbjct: 361  EDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQRGQGEK 406



 Score = 48.5 bits (114), Expect = 6e-05
 Identities = 26/52 (50%), Positives = 35/52 (67%), Gaps = 4/52 (7%)

Query: 1757 LGKKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEK 1808
            L    + E+E+ EEE EE EEE EEEEE +EE    EE EE+EEE +E +++
Sbjct: 354  LASLSDDEDEEEEEEGEEEEEEAEEEEEEDEE----EEEEEEEEEEEEPQQR 401



 Score = 48.1 bits (113), Expect = 8e-05
 Identities = 24/46 (52%), Positives = 33/46 (71%)

Query: 1770 EEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEKVSWAGIG 1815
            ++E+E EEEE EEEE E EE  +E+ EE+EEE +E+EE+    G G
Sbjct: 359  DDEDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQRGQG 404



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 24/47 (51%), Positives = 32/47 (68%)

Query: 1748 EDRPEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEE 1794
            +D  E     G++EE E E+ EEE+EE EEEEEEEEE E ++ G+ E
Sbjct: 359  DDEDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQRGQGE 405



 Score = 39.3 bits (90), Expect = 0.038
 Identities = 25/48 (52%), Positives = 30/48 (62%), Gaps = 4/48 (8%)

Query: 1776 EEEEEEEEETEEEELGKEEIEEKEEERDEKEEKVSWAGIGPTPQPESQ 1823
            +E+EEEEEE EEEE   EE EE+EEE DE+EE+         PQ   Q
Sbjct: 360  DEDEEEEEEGEEEE---EEAEEEEEE-DEEEEEEEEEEEEEEPQQRGQ 403



 Score = 36.6 bits (83), Expect = 0.24
 Identities = 19/60 (31%), Positives = 34/60 (56%)

Query: 1736 SSWEDGKGKQPKEDRPEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEI 1795
            +S  D + ++ +E+  E      ++EE +EE+ EEEEEE EEE ++  + E+      +I
Sbjct: 355  ASLSDDEDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQRGQGEKSATPSRKI 414



 Score = 35.8 bits (81), Expect = 0.41
 Identities = 24/53 (45%), Positives = 32/53 (60%), Gaps = 6/53 (11%)

Query: 1761 EEGEEEKGEEEE-----EELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEK 1808
            EEG E+  E  E     + L    ++E+E EEEE G+EE EE EEE +E EE+
Sbjct: 335  EEGCEQLQEVLEGFNMAKVLASLSDDEDEEEEEE-GEEEEEEAEEEEEEDEEE 386


>gi|169210053 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 185

 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 32/53 (60%), Positives = 41/53 (77%), Gaps = 2/53 (3%)

Query: 1759 KKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEK--EEKV 1809
            ++EE EEE+ E EEEE EEE+EE+EE EE+E  KEE EE+EE+  +K  EEKV
Sbjct: 119  EEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKV 171



 Score = 55.8 bits (133), Expect = 4e-07
 Identities = 31/65 (47%), Positives = 43/65 (66%)

Query: 1742 KGKQPKEDRPEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEE 1801
            +G   +E+  E      ++EE EEEK E+EEEE +EEE+EE+E EEE+ GK+  EEK EE
Sbjct: 114  QGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEE 173

Query: 1802 RDEKE 1806
              + E
Sbjct: 174  EIDTE 178



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 27/47 (57%), Positives = 33/47 (70%)

Query: 1761 EEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEE 1807
            EE   ++G   EEE  EEEEEE E EE+E  KEE EE+EE+ +EKEE
Sbjct: 108  EECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEE 154



 Score = 48.9 bits (115), Expect = 5e-05
 Identities = 25/48 (52%), Positives = 36/48 (75%)

Query: 1761 EEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEK 1808
            ++G   + EE EEE EE EEEE+E E+EE  +EE +E+E+E DE+EE+
Sbjct: 113  QQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEE 160



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 28/66 (42%), Positives = 42/66 (63%), Gaps = 5/66 (7%)

Query: 1731 LPVPSSSWEDGKGKQPKEDRPEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETEEEEL 1790
            LPV     E+ + +  +E++ E      K+E+ EEE+ EEE+EE EEEEE+E +  EEE 
Sbjct: 116  LPVEEEEVEEEEEEVEEEEKEEE-----KEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEK 170

Query: 1791 GKEEIE 1796
             +EEI+
Sbjct: 171  VEEEID 176



 Score = 44.7 bits (104), Expect = 9e-04
 Identities = 23/44 (52%), Positives = 31/44 (70%)

Query: 1765 EEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEK 1808
            EE   ++   +EEEE EEEE E EE  KEE +E++EE +EKEE+
Sbjct: 108  EECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEE 151



 Score = 35.0 bits (79), Expect = 0.71
 Identities = 20/56 (35%), Positives = 34/56 (60%), Gaps = 4/56 (7%)

Query: 1739 EDGKGKQPKEDRPEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEE 1794
            E+ K ++ +ED  E      K+EE EE++ EEE+E  + EEE+ EE  + E+ + +
Sbjct: 132  EEEKEEEKEEDEEEEE----KEEEKEEDEEEEEKEGKKMEEEKVEEEIDTEIQRTQ 183


>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
          Length = 709

 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 32/73 (43%), Positives = 48/73 (65%), Gaps = 4/73 (5%)

Query: 1736 SSWEDGKGKQPKEDRPEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEI 1795
            SS E G   + +E+  E       +E+ E E+  EE+EE++E+ EEEEE EEEE  +EE 
Sbjct: 190  SSDEQGNNTENEEEGVEE----DVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEE 245

Query: 1796 EEKEEERDEKEEK 1808
            EE+E E+DE+++K
Sbjct: 246  EEEEYEQDERDQK 258



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 32/65 (49%), Positives = 43/65 (66%), Gaps = 3/65 (4%)

Query: 1739 EDGKGKQPKEDRPEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEK 1798
            E+G  +  +ED  E      +++E  +E GEEEEEE EEEEEEEEE EEEE  ++E ++K
Sbjct: 202  EEGVEEDVEED--EEVEEDAEEDEEVDEDGEEEEEE-EEEEEEEEEEEEEEYEQDERDQK 258

Query: 1799 EEERD 1803
            EE  D
Sbjct: 259  EEGND 263



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 32/90 (35%), Positives = 50/90 (55%), Gaps = 25/90 (27%)

Query: 1761 EEGEEEKGEEE--EEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEKVSWAGIGPTP 1818
            E+G   + EEE  EE++EE+EE EE+ EE+E   E+ EE+EEE +E+EE+          
Sbjct: 193  EQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEE---------- 242

Query: 1819 QPESQESMQWQWQQQLNVMVKEEQEQDEKE 1848
              E +E  ++           E+ E+D+KE
Sbjct: 243  --EEEEEEEY-----------EQDERDQKE 259



 Score = 48.5 bits (114), Expect = 6e-05
 Identities = 28/55 (50%), Positives = 37/55 (67%), Gaps = 5/55 (9%)

Query: 1761 EEGEEEKGEEEEEELEEEEEEEEETEEEELGKEE----IEEKEEERDEKEEKVSW 1811
            E+GEEE+ EEEEEE EEEEEEEEE E++E  ++E     + + E  D   E VS+
Sbjct: 227  EDGEEEEEEEEEEE-EEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSF 280



 Score = 48.1 bits (113), Expect = 8e-05
 Identities = 27/96 (28%), Positives = 48/96 (50%), Gaps = 10/96 (10%)

Query: 1752 EHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEKVSW 1811
            +H  G     + +    E EEE +EE+ EE+EE EE+    EE++E  EE +E+EE+   
Sbjct: 182  DHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEE--- 238

Query: 1812 AGIGPTPQPESQESMQWQWQQQLNVMVKEEQEQDEK 1847
                   + E +E  + +++Q      +E  + D +
Sbjct: 239  -------EEEEEEEEEEEYEQDERDQKEEGNDYDTR 267



 Score = 37.7 bits (86), Expect = 0.11
 Identities = 24/75 (32%), Positives = 36/75 (48%), Gaps = 27/75 (36%)

Query: 1761 EEGEEEKGEEE---------------------------EEELEEEEEEEEETEEEELGKE 1793
            +  +EE   EE                           EE++EE+EE EE+ EE+E   E
Sbjct: 168  QSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDE 227

Query: 1794 EIEEKEEERDEKEEK 1808
            + EE+EEE +E+EE+
Sbjct: 228  DGEEEEEEEEEEEEE 242



 Score = 35.8 bits (81), Expect = 0.41
 Identities = 27/91 (29%), Positives = 42/91 (46%), Gaps = 14/91 (15%)

Query: 1758 GKKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEKVSWAGIGPT 1817
            G   E       +E+    E EEE  E + EE   EE+EE  EE +E +E       G  
Sbjct: 180  GSDHETGSSGSSDEQGNNTENEEEGVEEDVEE--DEEVEEDAEEDEEVDED------GEE 231

Query: 1818 PQPESQESMQWQWQQQLNVMVKEEQEQDEKE 1848
             + E +E  + + +++      EE EQDE++
Sbjct: 232  EEEEEEEEEEEEEEEE------EEYEQDERD 256



 Score = 33.5 bits (75), Expect = 2.1
 Identities = 24/105 (22%), Positives = 46/105 (43%), Gaps = 15/105 (14%)

Query: 1739 EDGKGKQPKEDRPEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEI--- 1795
            EDG+ ++ +E+  E      ++EE EEE  ++E ++ EE  + +  +E  + G E +   
Sbjct: 227  EDGEEEEEEEEEEEE-----EEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFT 281

Query: 1796 -------EEKEEERDEKEEKVSWAGIGPTPQPESQESMQWQWQQQ 1833
                      +   ++K+E+    GI P     S  S    +  Q
Sbjct: 282  DGSVRSGSGTDGSDEKKKERKRARGISPIVFDRSGSSASESYADQ 326


>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
          Length = 727

 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 32/73 (43%), Positives = 48/73 (65%), Gaps = 4/73 (5%)

Query: 1736 SSWEDGKGKQPKEDRPEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEI 1795
            SS E G   + +E+  E       +E+ E E+  EE+EE++E+ EEEEE EEEE  +EE 
Sbjct: 190  SSDEQGNNTENEEEGVEE----DVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEE 245

Query: 1796 EEKEEERDEKEEK 1808
            EE+E E+DE+++K
Sbjct: 246  EEEEYEQDERDQK 258



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 32/65 (49%), Positives = 43/65 (66%), Gaps = 3/65 (4%)

Query: 1739 EDGKGKQPKEDRPEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEK 1798
            E+G  +  +ED  E      +++E  +E GEEEEEE EEEEEEEEE EEEE  ++E ++K
Sbjct: 202  EEGVEEDVEED--EEVEEDAEEDEEVDEDGEEEEEE-EEEEEEEEEEEEEEYEQDERDQK 258

Query: 1799 EEERD 1803
            EE  D
Sbjct: 259  EEGND 263



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 32/90 (35%), Positives = 50/90 (55%), Gaps = 25/90 (27%)

Query: 1761 EEGEEEKGEEE--EEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEKVSWAGIGPTP 1818
            E+G   + EEE  EE++EE+EE EE+ EE+E   E+ EE+EEE +E+EE+          
Sbjct: 193  EQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEE---------- 242

Query: 1819 QPESQESMQWQWQQQLNVMVKEEQEQDEKE 1848
              E +E  ++           E+ E+D+KE
Sbjct: 243  --EEEEEEEY-----------EQDERDQKE 259



 Score = 48.5 bits (114), Expect = 6e-05
 Identities = 28/55 (50%), Positives = 37/55 (67%), Gaps = 5/55 (9%)

Query: 1761 EEGEEEKGEEEEEELEEEEEEEEETEEEELGKEE----IEEKEEERDEKEEKVSW 1811
            E+GEEE+ EEEEEE EEEEEEEEE E++E  ++E     + + E  D   E VS+
Sbjct: 227  EDGEEEEEEEEEEE-EEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSF 280



 Score = 48.1 bits (113), Expect = 8e-05
 Identities = 27/96 (28%), Positives = 48/96 (50%), Gaps = 10/96 (10%)

Query: 1752 EHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEKVSW 1811
            +H  G     + +    E EEE +EE+ EE+EE EE+    EE++E  EE +E+EE+   
Sbjct: 182  DHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEE--- 238

Query: 1812 AGIGPTPQPESQESMQWQWQQQLNVMVKEEQEQDEK 1847
                   + E +E  + +++Q      +E  + D +
Sbjct: 239  -------EEEEEEEEEEEYEQDERDQKEEGNDYDTR 267



 Score = 37.7 bits (86), Expect = 0.11
 Identities = 24/75 (32%), Positives = 36/75 (48%), Gaps = 27/75 (36%)

Query: 1761 EEGEEEKGEEE---------------------------EEELEEEEEEEEETEEEELGKE 1793
            +  +EE   EE                           EE++EE+EE EE+ EE+E   E
Sbjct: 168  QSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDE 227

Query: 1794 EIEEKEEERDEKEEK 1808
            + EE+EEE +E+EE+
Sbjct: 228  DGEEEEEEEEEEEEE 242



 Score = 35.8 bits (81), Expect = 0.41
 Identities = 27/91 (29%), Positives = 42/91 (46%), Gaps = 14/91 (15%)

Query: 1758 GKKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEKVSWAGIGPT 1817
            G   E       +E+    E EEE  E + EE   EE+EE  EE +E +E       G  
Sbjct: 180  GSDHETGSSGSSDEQGNNTENEEEGVEEDVEE--DEEVEEDAEEDEEVDED------GEE 231

Query: 1818 PQPESQESMQWQWQQQLNVMVKEEQEQDEKE 1848
             + E +E  + + +++      EE EQDE++
Sbjct: 232  EEEEEEEEEEEEEEEE------EEYEQDERD 256



 Score = 33.1 bits (74), Expect = 2.7
 Identities = 16/57 (28%), Positives = 32/57 (56%), Gaps = 5/57 (8%)

Query: 1739 EDGKGKQPKEDRPEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEI 1795
            EDG+ ++ +E+  E      ++EE EEE  ++E ++ EE  + +  +E  + G E +
Sbjct: 227  EDGEEEEEEEEEEEE-----EEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESV 278


>gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapiens]
          Length = 436

 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 34/115 (29%), Positives = 65/115 (56%), Gaps = 6/115 (5%)

Query: 1739 EDGKGKQPKEDRPEHYPGLGKKEEGE-EEKGEEEEEELEEEEEEEEETEEEELGKEEIEE 1797
            E+   +Q ++ R +    L +KE+ E EE+  E+EE++ E+EE+  E EE+   +EE   
Sbjct: 261  EEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMR 320

Query: 1798 KEEERDEKEEKVSWAGIGPTPQPESQESMQWQWQQQLNVMVKEEQEQDEKEAIRR 1852
            ++EE+  K+E+  W       + +  E  +  W+Q+  +  +EEQ Q ++E +R+
Sbjct: 321  EQEEQMGKQEEQMW-----EQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRK 370



 Score = 52.0 bits (123), Expect = 6e-06
 Identities = 26/91 (28%), Positives = 54/91 (59%)

Query: 1758 GKKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEKVSWAGIGPT 1817
            G+  E EE+ GE+EE+  ++EE+  E+ E+    +E++ E+EE+  ++EE+V        
Sbjct: 199  GQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMR 258

Query: 1818 PQPESQESMQWQWQQQLNVMVKEEQEQDEKE 1848
             Q E     + Q ++Q   M+K++++ +++E
Sbjct: 259  KQEEQMREQEEQMREQEEQMLKQKEQTEQEE 289



 Score = 48.9 bits (115), Expect = 5e-05
 Identities = 30/113 (26%), Positives = 64/113 (56%), Gaps = 4/113 (3%)

Query: 1739 EDGKGKQPKEDRPEHYPGLGKKEEG---EEEKGEEEEEELEEEEEEEEETEEEELGKEEI 1795
            E+  G+Q ++ R +    +G++EE    +EE+ +++EE++ ++EE+  E EE+   +EE 
Sbjct: 219  EEQMGEQEEQMRKQEEQ-MGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQ 277

Query: 1796 EEKEEERDEKEEKVSWAGIGPTPQPESQESMQWQWQQQLNVMVKEEQEQDEKE 1848
              K++E+ E+EE+          Q E     + Q ++Q   M ++E++  ++E
Sbjct: 278  MLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQE 330



 Score = 48.5 bits (114), Expect = 6e-05
 Identities = 33/117 (28%), Positives = 69/117 (58%), Gaps = 12/117 (10%)

Query: 1739 EDGKGKQPKEDRPEHYPGLGKKEEG---EEEKGEEEEEELEEEEEEEEETEEEELGKEE- 1794
            E+  G+Q +E   +    +G++EE    +EE+  E+EE+++++EE+ ++ EE+   +EE 
Sbjct: 205  EEQMGEQ-EEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQ 263

Query: 1795 IEEKEEERDEKEEKVSWAGIGPTPQPESQESMQWQWQQQLNVMVKEEQEQDEKEAIR 1851
            + E+EE+  E+EE++         Q E  E  +   +Q+  +  +EEQ ++++E +R
Sbjct: 264  MREQEEQMREQEEQM-------LKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMR 313



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 25/90 (27%), Positives = 53/90 (58%), Gaps = 4/90 (4%)

Query: 1758 GKKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEKVSWAGIGPT 1817
            G+  E E + GE+EE+  E+EE+ +++ E+    +E++ ++EE+  E+EE+V        
Sbjct: 192  GQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQ----KQE 247

Query: 1818 PQPESQESMQWQWQQQLNVMVKEEQEQDEK 1847
             Q + QE    + ++Q+    ++ +EQ+E+
Sbjct: 248  EQVQKQEEQMRKQEEQMREQEEQMREQEEQ 277



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 27/91 (29%), Positives = 52/91 (57%), Gaps = 7/91 (7%)

Query: 1758 GKKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEKVSWAGIGPT 1817
            G+  E E + GE+E +  E+EE+  E+ E+ +  +E++ E+EE+  ++EE++        
Sbjct: 185  GQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMG------- 237

Query: 1818 PQPESQESMQWQWQQQLNVMVKEEQEQDEKE 1848
             Q E  +  + Q Q+Q   M K+E++  E+E
Sbjct: 238  EQEEQVQKQEEQVQKQEEQMRKQEEQMREQE 268



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 45/202 (22%), Positives = 94/202 (46%), Gaps = 18/202 (8%)

Query: 1651 EESETSEEKSPNKWGPVSKQKKQLLVDILTTIIRGLLEDK-NFHEAVDQSLVEQVPYFRQ 1709
            E+ +  EE+   +   + KQ++Q+          G  E++    E   Q   EQ+    +
Sbjct: 213  EQMQKQEEQMGEQEEQMRKQEEQM----------GEQEEQVQKQEEQVQKQEEQMRKQEE 262

Query: 1710 FWNEQSTKFMDQKNSLYLMPILPVPSSSWEDGKGKQPKEDRPEHYPGLGKKE---EGEEE 1766
               EQ  +  +Q+  +    +     +  E+  G+Q ++ R +      ++E   E EE+
Sbjct: 263  QMREQEEQMREQEEQM----LKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQ 318

Query: 1767 KGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEKVSWAGIGPTPQPESQESM 1826
              E+EE+  ++EE+  E+ E+    KE++ ++EE+  E+EE++         Q E     
Sbjct: 319  MREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQ 378

Query: 1827 QWQWQQQLNVMVKEEQEQDEKE 1848
            + Q ++Q   M K+E++  E++
Sbjct: 379  EEQMRKQEEQMRKQEEQMGEQK 400



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 35/142 (24%), Positives = 74/142 (52%), Gaps = 19/142 (13%)

Query: 1747 KEDRPEHYPGLGKKEEGE--EEKGEEEEEELEEEEEEEEETEEE-ELGKEEIE--EKEEE 1801
            +E +     G  +++EG+  E++G+  E+E +  E+E +  E+E ++G++E +  E+EE+
Sbjct: 155  QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQ 214

Query: 1802 RDEKEEKVSWAGIGPTPQPESQESMQWQ----WQQQLNVMVKEEQEQDEKEAIRRLPAFA 1857
              ++EE++           E +E M+ Q     +Q+  V  +EEQ Q ++E +R+     
Sbjct: 215  MQKQEEQMG----------EQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQM 264

Query: 1858 NLQEALLENMIQNILVEASRGE 1879
              QE  +    + +L +  + E
Sbjct: 265  REQEEQMREQEEQMLKQKEQTE 286



 Score = 40.4 bits (93), Expect = 0.017
 Identities = 30/120 (25%), Positives = 59/120 (49%), Gaps = 17/120 (14%)

Query: 1739 EDGKGKQP------KEDRPEHYPGLGKKEEG----EEEKGEEEEEELEEEEEEEEETEEE 1788
            E+  GKQ       KE   E    + K+EE     EE+  ++EE+  ++EE+  ++ E+ 
Sbjct: 323  EEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQM 382

Query: 1789 ELGKEEIEEKEEERDEKEEKVSWAGIGPTPQPESQESMQWQWQQQLNVMVKEEQEQDEKE 1848
               +E++ ++EE+  E++E++         Q E     + Q  +Q   M K+E+   E++
Sbjct: 383  RKQEEQMRKQEEQMGEQKEQMG-------EQKEQMREQEEQMGEQKEQMRKQEEHMGEQK 435



 Score = 40.0 bits (92), Expect = 0.022
 Identities = 28/107 (26%), Positives = 54/107 (50%), Gaps = 5/107 (4%)

Query: 1747 KEDRPEHYPGLGKKEEGE--EEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDE 1804
            +E +     G  +++EG+  E++G+  E+E +  E+E +  E+E   +E+  +  E+  +
Sbjct: 134  QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 193

Query: 1805 KEEKVSWAGIGPTPQPESQESMQWQWQQ---QLNVMVKEEQEQDEKE 1848
              E+    G       E +E MQ Q +Q   Q   M K+E++  E+E
Sbjct: 194  MGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQE 240



 Score = 38.5 bits (88), Expect = 0.064
 Identities = 29/106 (27%), Positives = 60/106 (56%), Gaps = 18/106 (16%)

Query: 1709 QFWNEQSTKFMDQKNSLYLMPILPVPSSSWEDGKGKQPKEDRPEHYPGLGKKEEG---EE 1765
            Q W EQ  +  +QK  ++            E+  G+Q +E   +    + K+EE    +E
Sbjct: 332  QMW-EQKEQMWEQKEQMWKQ----------EEQMGEQ-EEQMQKQEEQVRKQEEQMRKQE 379

Query: 1766 EKGEEEEEELEEEEEEEEETEEEELG--KEEIEEKEEERDEKEEKV 1809
            E+  ++EE++ ++EE+  E ++E++G  KE++ E+EE+  E++E++
Sbjct: 380  EQMRKQEEQMRKQEEQMGE-QKEQMGEQKEQMREQEEQMGEQKEQM 424



 Score = 37.7 bits (86), Expect = 0.11
 Identities = 27/127 (21%), Positives = 61/127 (48%), Gaps = 5/127 (3%)

Query: 1747 KEDRPEHYPGLGKKEEGE--EEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDE 1804
            +E +     G  +++EG+  E++G+  E+E +  E+E +  E+E   +E+  +  E+  +
Sbjct: 127  QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 186

Query: 1805 KEEKVSWAGIGPTPQPESQESMQWQWQQQLNVMVKEEQEQDEKEAIRRLPAFANLQEALL 1864
              E+    G       E +E M    +Q+  +  +EEQ  +++E +R+       QE  +
Sbjct: 187  VREQEGQMGEQEGQMGEQEEQM---GEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQV 243

Query: 1865 ENMIQNI 1871
            +   + +
Sbjct: 244  QKQEEQV 250



 Score = 33.9 bits (76), Expect = 1.6
 Identities = 26/109 (23%), Positives = 56/109 (51%), Gaps = 9/109 (8%)

Query: 1739 EDGKGKQPKEDRPEHYPGLGKKEEGE--EEKGEEEEEELEEEEEEEEETEEE-ELGKEEI 1795
            E  K   P+E +     G  +++EG+  E++G+  E+E +  E+E +  E+E ++ ++E 
Sbjct: 42   ETDKIPLPQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 101

Query: 1796 EEKEEERDEKEEKVSWAGIGPTPQPESQESMQWQWQQQLNVMVKEEQEQ 1844
            + +E+E   +E++      G   + E Q   Q    ++    V+E++ Q
Sbjct: 102  QVREQEGQVREQE------GQVREQEGQVREQEGQVREQEGQVREQEGQ 144



 Score = 31.6 bits (70), Expect = 7.8
 Identities = 24/106 (22%), Positives = 57/106 (53%), Gaps = 10/106 (9%)

Query: 1747 KEDRPEHYPGLGKKEEGE--EEKGEEEEEELEEEEEEEEETEEE-ELGKEEIEEKEEERD 1803
            +E +     G  +++EG+  E++G+  E+E +  E+E +  E+E ++ ++E + +E+E  
Sbjct: 99   QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 158

Query: 1804 EKEEKVSWAGIGPTPQPESQ-ESMQWQWQQQLNVMVKEEQEQDEKE 1848
             +E++      G   + E Q    + Q ++Q   + ++E +  E+E
Sbjct: 159  VREQE------GQVREQEGQVREQEGQVREQEGQVREQEGQMGEQE 198


>gi|87298939 hypothetical protein LOC131831 [Homo sapiens]
          Length = 663

 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 32/56 (57%), Positives = 39/56 (69%), Gaps = 3/56 (5%)

Query: 1751 PEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKE 1806
            P  +   GKK++ E E+  EEEEE EE EEEEEE EEEE   EE+EE+EEE  E+E
Sbjct: 7    PSGFGDPGKKDQKESEEELEEEEEEEEVEEEEEEVEEEE---EEVEEEEEEVVEEE 59



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 30/55 (54%), Positives = 38/55 (69%)

Query: 1755 PGLGKKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEKV 1809
            PG   ++E EEE  EEEEEE  EEEEEE E EEEE+ +EE E  EEE   +E+++
Sbjct: 13   PGKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQEL 67



 Score = 52.0 bits (123), Expect = 6e-06
 Identities = 25/51 (49%), Positives = 38/51 (74%)

Query: 1759 KKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEKV 1809
            +   G  + G+++++E EEE EEEEE EE E  +EE+EE+EEE +E+EE+V
Sbjct: 5    RSPSGFGDPGKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEV 55



 Score = 51.2 bits (121), Expect = 1e-05
 Identities = 31/76 (40%), Positives = 48/76 (63%), Gaps = 6/76 (7%)

Query: 1758 GKKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEKVSWAGIGPT 1817
            G  + G++++ E EEE  EEEEEEE E EEEE+ +EE E +EEE +  EE++    +G  
Sbjct: 9    GFGDPGKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEEL----VGEE 64

Query: 1818 PQPESQE--SMQWQWQ 1831
             + E+ E  S ++ W+
Sbjct: 65   QELEAPETFSEEYLWK 80



 Score = 49.3 bits (116), Expect = 4e-05
 Identities = 32/72 (44%), Positives = 44/72 (61%), Gaps = 1/72 (1%)

Query: 1743 GKQPKEDRPEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKE-EIEEKEEE 1801
            GK+ +++  E      ++EE EEE+ E EEEE E EEEEEE  EEE +G+E E+E  E  
Sbjct: 14   GKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAPETF 73

Query: 1802 RDEKEEKVSWAG 1813
             +E   KV+  G
Sbjct: 74   SEEYLWKVTDIG 85



 Score = 48.1 bits (113), Expect = 8e-05
 Identities = 33/68 (48%), Positives = 40/68 (58%), Gaps = 2/68 (2%)

Query: 1741 GKGKQPKEDRPEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETE--EEELGKEEIEEK 1798
            G G   K+D+ E    L ++EE EE + EEEE E EEEE EEEE E  EEEL  EE E +
Sbjct: 9    GFGDPGKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELE 68

Query: 1799 EEERDEKE 1806
              E   +E
Sbjct: 69   APETFSEE 76


>gi|210032580 SET domain containing 1B [Homo sapiens]
          Length = 1923

 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 33/121 (27%), Positives = 64/121 (52%), Gaps = 11/121 (9%)

Query: 1739 EDGKGKQPKEDRPEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEK 1798
            + G  +  KE   E      ++EE EEE+ EE++++ + ++ +E E ++E+    E  EK
Sbjct: 1030 DSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEK 1089

Query: 1799 EEERDEKEEKVS--WAGIGPTPQPESQESMQWQ---------WQQQLNVMVKEEQEQDEK 1847
            +E   ++EE VS   +    T   ES ES +++          + +  V+ +EE+E++E+
Sbjct: 1090 DEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEE 1149

Query: 1848 E 1848
            E
Sbjct: 1150 E 1150



 Score = 38.5 bits (88), Expect = 0.064
 Identities = 31/117 (26%), Positives = 48/117 (41%), Gaps = 3/117 (2%)

Query: 1735 SSSWEDGKGKQPKEDRPEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEE 1794
            S + E  +G   +E+         +     E     E E   E      E EEE + +EE
Sbjct: 1084 SEASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREE 1143

Query: 1795 IEEKEEERDEKEEKVSWAGIGPTP-QPESQESMQWQWQQQLNVMVKEEQEQDEKEAI 1850
             EE+EEE    EE  S A  GP   + + +E+        ++ +  EE+   E EA+
Sbjct: 1144 EEEEEEEEMVAEE--SMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAV 1198



 Score = 32.0 bits (71), Expect = 6.0
 Identities = 34/120 (28%), Positives = 52/120 (43%), Gaps = 22/120 (18%)

Query: 1720 DQKNSLYLMPILPVPSSSWEDGKGKQPKEDRPEHYPGLGKKEEG----EEEKGEEEEEEL 1775
            D++ ++ ++      +SS E  +  +  E   E  P   + EE     EEE+ EEEEE +
Sbjct: 1095 DEEETVSIVTSKAEATSSSESSESSE-FESSSESSPSSSEDEEEVVAREEEEEEEEEEMV 1153

Query: 1776 EEE-------EEEEEETEE----------EELGKEEIEEKEEERDEKEEKVSWAGIGPTP 1818
             EE       E+ E++ EE          + LG EE  + E E    EE+ S     P P
Sbjct: 1154 AEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSMLDEPPLP 1213


>gi|211904182 DDB1 and CUL4 associated factor 8-like 2 [Homo sapiens]
          Length = 631

 Score = 56.2 bits (134), Expect = 3e-07
 Identities = 33/75 (44%), Positives = 44/75 (58%), Gaps = 7/75 (9%)

Query: 1753 HYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEKVSWA 1812
            HYP +G++E   EE+ EE +EE  EEEEEEEE EEE       EE+EEE +E++ +    
Sbjct: 102  HYPLVGEEETEREEEDEEIQEEGGEEEEEEEEEEEE-------EEEEEEEEEEQPRAGPQ 154

Query: 1813 GIGPTPQPESQESMQ 1827
            G G   +  S E  Q
Sbjct: 155  GSGGNHEQYSLEEDQ 169



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 36/111 (32%), Positives = 51/111 (45%), Gaps = 10/111 (9%)

Query: 1713 EQSTKFMDQKNSLYLMPILPVPSSSWEDGKGKQPKEDRPEHYPGLGKKEEGEEEKGEEEE 1772
            E    F+    SL+  P++         G+ +  +E+  E     G +EE EEE+ EEEE
Sbjct: 88   EDFEHFLMSGESLFHYPLV---------GEEETEREEEDEEIQEEGGEEEEEEEEEEEEE 138

Query: 1773 EELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEKVSWAGIGPTPQPESQ 1823
            EE EEEEEE+     +  G    +   EE    EE VS +     P+P  Q
Sbjct: 139  EEEEEEEEEQPRAGPQGSGGNHEQYSLEEDQALEEWVS-SETSALPRPRWQ 188



 Score = 32.0 bits (71), Expect = 6.0
 Identities = 35/132 (26%), Positives = 57/132 (43%), Gaps = 23/132 (17%)

Query: 1765 EEKGEEEEEELEEEEEEEEETEEEELGKEE-------IEEKEEERDEKEEKVSWAGIGPT 1817
            E +  ++E   E+ E E  E  E  L   E       + E+E ER+E++E++   G G  
Sbjct: 69   ENRSSDQESASEDIELESLEDFEHFLMSGESLFHYPLVGEEETEREEEDEEIQEEG-GEE 127

Query: 1818 PQPESQESMQWQWQQQLNVMVKEEQEQDEKEAIRRLP--AFANLQEALLENMIQNILVEA 1875
             + E +E  +           +EE+E++E+E  R  P  +  N ++  LE      L E 
Sbjct: 128  EEEEEEEEEE-----------EEEEEEEEEEQPRAGPQGSGGNHEQYSLEE--DQALEEW 174

Query: 1876 SRGEVVLTSRPR 1887
               E     RPR
Sbjct: 175  VSSETSALPRPR 186


>gi|21735415 centromere protein B [Homo sapiens]
          Length = 599

 Score = 56.2 bits (134), Expect = 3e-07
 Identities = 30/50 (60%), Positives = 37/50 (74%)

Query: 1759 KKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEK 1808
            ++EE EEE+GE EEEE E EEEEEE  E EELG+EE  E+E + D  EE+
Sbjct: 411  EEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEE 460



 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 39/91 (42%), Positives = 51/91 (56%), Gaps = 19/91 (20%)

Query: 1765 EEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEKVSWAGIGPTPQPESQE 1824
            + +GEEEEEE EEEEEEE E EEEE   EE EE+EEE  E EE      +G   + E   
Sbjct: 402  KSEGEEEEEEEEEEEEEEGEGEEEE---EEGEEEEEEGGEGEE------LGEEEEVE--- 449

Query: 1825 SMQWQWQQQLNVMVKEEQEQDEKEAIRRLPA 1855
                   ++ +V   EE+E+DE+ +   L A
Sbjct: 450  -------EEGDVDSDEEEEEDEESSSEGLEA 473



 Score = 52.4 bits (124), Expect = 4e-06
 Identities = 35/73 (47%), Positives = 41/73 (56%), Gaps = 1/73 (1%)

Query: 1761 EEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEKVSWAGIGPTPQP 1820
            EE EEE+ EEEEEE E EEEEEE  EEEE G E  E  EEE  E+E  V         + 
Sbjct: 406  EEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEEDEE 465

Query: 1821 ESQESMQWQ-WQQ 1832
             S E ++ + W Q
Sbjct: 466  SSSEGLEAEDWAQ 478



 Score = 52.0 bits (123), Expect = 6e-06
 Identities = 32/85 (37%), Positives = 48/85 (56%), Gaps = 1/85 (1%)

Query: 1729 PILPVPSSSWEDGKGKQPKEDRPEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETEEE 1788
            P   + +S   +G+ ++ +E+  E   G G++EE E E+ EEE  E EE  EEEE  EE 
Sbjct: 393  PNATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEG 452

Query: 1789 ELGKEEIEEKEEE-RDEKEEKVSWA 1812
            ++  +E EE++EE   E  E   WA
Sbjct: 453  DVDSDEEEEEDEESSSEGLEAEDWA 477



 Score = 38.9 bits (89), Expect = 0.049
 Identities = 31/106 (29%), Positives = 49/106 (46%), Gaps = 37/106 (34%)

Query: 1739 EDGKGKQPKEDRPEHYPGLGKKEE-GEEEKGEEEEE-ELEEEEEEEEETEEEEL------ 1790
            E+G+G++ +E+  E     G+ EE GEEE+ EEE + + +EEEEE+EE+  E L      
Sbjct: 418  EEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWA 477

Query: 1791 -----------------------------GKEEIEEKEEERDEKEE 1807
                                         G++   + EEE DE+E+
Sbjct: 478  QGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEED 523



 Score = 35.0 bits (79), Expect = 0.71
 Identities = 15/41 (36%), Positives = 27/41 (65%)

Query: 1755 PGLGKKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEI 1795
            P L   E GE+   + EEE+ EEE++E+E+ +++E   +E+
Sbjct: 499  PTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEV 539



 Score = 32.3 bits (72), Expect = 4.6
 Identities = 15/39 (38%), Positives = 26/39 (66%), Gaps = 5/39 (12%)

Query: 1766 EKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDE 1804
            E GE+ + + EEE++EEE+ E+     E+ ++ EE+ DE
Sbjct: 505  EGGEDSDSDSEEEDDEEEDDED-----EDDDDDEEDGDE 538


>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
            [Homo sapiens]
          Length = 899

 Score = 56.2 bits (134), Expect = 3e-07
 Identities = 60/234 (25%), Positives = 98/234 (41%), Gaps = 54/234 (23%)

Query: 1641 RELPKRKAPREESETSEEKSPNKWGPVSKQKKQLLVDILTTIIRGLLEDKNFHEAVDQSL 1700
            +EL ++K  RE+ E  +E+    W    K ++Q              E+K + +  ++ L
Sbjct: 335  KELREQKELREQEEQMQEQEEKMWEQEEKMREQ--------------EEKMWRQ--EERL 378

Query: 1701 VEQVPYFRQFWNEQSTKFMDQKNSLYLMPILPVPSSSWEDGKGKQPKEDRPEHYPGLGKK 1760
             EQ    R    EQ  K  DQ+  +            WE  +  + KE+R      + ++
Sbjct: 379  WEQEKQMR----EQEQKMRDQEERM------------WEQDERLREKEERMREQEKMWEQ 422

Query: 1761 EEG--EEEKGEE-------------EEEELEEEEEEEEETEEEELGKEEIEEKEEERDEK 1805
             E   EE+K +E             EEE + E E++  E EE    +EE  +K+EE   +
Sbjct: 423  VEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWE 482

Query: 1806 EEKVSWAGIGPTPQPE---SQESMQWQ----WQQQLNVMVKEEQEQDEKEAIRR 1852
            +E+  W       Q E    QE MQ Q    W+Q+  +  +EE    EK+  R+
Sbjct: 483  QEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQ 536



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 56/220 (25%), Positives = 99/220 (45%), Gaps = 14/220 (6%)

Query: 1629 NFFSEFPCHFLHRELPKRKAPREESETSEEKSPNKWGPVSKQKKQLLVDILTTIIRGLLE 1688
            N + +    +  + LP++K    E E  +E+    W    K + Q   + +    + +  
Sbjct: 479  NMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQ---EEMWGQEKKMWR 535

Query: 1689 DKNFHEAVDQSLVEQVPYFRQFWNEQSTKFMDQKNSLYLMPILPVPSSSWEDGKGKQPKE 1748
             +   E  DQ + EQ    R    +Q  K  DQ+  +           +W D + K  +E
Sbjct: 536  QEKMREQEDQ-MWEQEEKMR----DQEQKMWDQEERME-KKTQEQEKKTW-DQEEKMREE 588

Query: 1749 DRPEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEE-IEEKEEERDEKEE 1807
            +R        KK   EEE   E+EE+++E+EE+ +E EE+   +EE ++E+EE+  E+EE
Sbjct: 589  ERMRERE---KKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEE 645

Query: 1808 KVSWAGIGPTPQPESQESMQWQWQQQLNVMVKEEQEQDEK 1847
            K+         Q    E  +  W+ +     ++ QEQ+EK
Sbjct: 646  KMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEK 685



 Score = 51.6 bits (122), Expect = 7e-06
 Identities = 53/208 (25%), Positives = 92/208 (44%), Gaps = 38/208 (18%)

Query: 1651 EESETSEEKSPNKWGPVSKQKKQLLVDILTTIIRGLLEDKNFHEAVDQSLVEQVPYFRQF 1710
            E+ E  +E+    W    K  +Q              E+K + +   Q L EQ     + 
Sbjct: 628  EQEEKMQEQEEKMWEQEEKMWEQ--------------EEKMWEQ---QRLPEQK---EKL 667

Query: 1711 WN----EQSTKFMDQKNSLYLMPILPVPSSSWEDGKGKQPKEDRPEHYPGLGKKEEGEEE 1766
            W     ++  K  +Q+  ++    +   +   E     Q K    E      KK   EEE
Sbjct: 668  WEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEE 727

Query: 1767 KGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEKVSWAGIGPTPQPESQESM 1826
               E+EE+++E+EE+ +E E      EE+ E+EE+  E+EEK+ W        PE +E +
Sbjct: 728  MMREQEEKMQEQEEKMQEQE------EEMWEQEEKMWEQEEKM-WE---QQRLPEQKEKL 777

Query: 1827 QWQ---WQQQLNVMVKEEQEQDEKEAIR 1851
             W+    Q+Q  +  +EE+ +D++E +R
Sbjct: 778  -WEHEKMQEQEKIWEQEEKMRDQEEKMR 804



 Score = 51.2 bits (121), Expect = 1e-05
 Identities = 46/203 (22%), Positives = 92/203 (45%), Gaps = 28/203 (13%)

Query: 1650 REESETSEEKSPNKWGPVSKQKKQLLVDILTTIIRGLLEDKNFHEAVDQSLVEQVPYFR- 1708
            RE+ E  +++  N W    K+ +Q     L      L E +   E  ++ + EQ    R 
Sbjct: 467  REQEEKMQKQEENMWEQEEKEWQQ---QRLPEQKEKLWEQEKMQEQ-EEKIWEQEEKIRD 522

Query: 1709 --QFWNEQSTKFMDQKNSLYLMPILPVPSSSWEDGKGKQPKEDRPEHYPGLGKKEEGEEE 1766
              + W ++   +  +K       +       WE  +  + +E +      +  +EE  E+
Sbjct: 523  QEEMWGQEKKMWRQEK-------MREQEDQMWEQEEKMRDQEQK------MWDQEERMEK 569

Query: 1767 KGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEKVSWAGIGPTPQPESQESM 1826
            K +E+E++  ++EE+  E E     ++++ E+EE   E+EEK+         + + QE  
Sbjct: 570  KTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQ------EQEEKMQEQE 623

Query: 1827 QWQWQQQLNVMVKEEQ--EQDEK 1847
            +  W+Q+  +  +EE+  EQ+EK
Sbjct: 624  EKMWEQEEKMQEQEEKMWEQEEK 646



 Score = 48.9 bits (115), Expect = 5e-05
 Identities = 55/224 (24%), Positives = 102/224 (45%), Gaps = 27/224 (12%)

Query: 1645 KRKAPREESETSEEKSPNKWGPVSKQKKQLLVDILTTIIRGLLEDKNFHEAVDQSLVEQV 1704
            + K P  ESE SE +   K     K+K +    +L  +    L+++ + +  ++ L EQ 
Sbjct: 231  QEKLPLAESEKSEIQLNVK---ELKRKLERAKFLLPQVQTNTLQEEMWRQ--EEELREQE 285

Query: 1705 PYFRQFWNEQSTKFMDQKNSLYLMPILPVPSSSWEDGKGKQPKED--RPEHYPGLGKKEE 1762
               R+    Q  K   Q+  L             ++GK ++ +E   R E      +KE 
Sbjct: 286  KKIRK----QEEKMWRQEERL-----------REQEGKMREQEEKMWRQEKRLREQEKEL 330

Query: 1763 GEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEKVSWAGIGPTPQPE- 1821
             E+EK   E++EL E+EE+ +E EE+   +EE   ++EE+  ++E+  W       + E 
Sbjct: 331  REQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQ 390

Query: 1822 ---SQESMQWQWQQQLNVMVKEEQEQDEK-EAIRRLPAFANLQE 1861
                QE   W+  ++L    +  +EQ++  E + ++     +QE
Sbjct: 391  KMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQE 434



 Score = 48.1 bits (113), Expect = 8e-05
 Identities = 47/209 (22%), Positives = 91/209 (43%), Gaps = 26/209 (12%)

Query: 1651 EESETSEEKSPNKWGPVSKQKKQLLVDILTTIIRGLLEDKNFHEAVDQSLVEQVPYFRQF 1710
            +E E  +E+    W     +KK    +  T     + E+++  E  ++ + E+    R+ 
Sbjct: 674  QEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMRER-EKKMREEEEMMREQ 732

Query: 1711 ---WNEQSTKFMDQKNSLYLMPILPVPSSSWEDGKGKQPKEDRPEHYPGLGKKEEGEEEK 1767
                 EQ  K  +Q+  ++           WE  +    ++  PE      +KE+  E +
Sbjct: 733  EEKMQEQEEKMQEQEEEMWEQE-----EKMWEQEEKMWEQQRLPE------QKEKLWEHE 781

Query: 1768 GEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEKVSWAGIGPTPQPESQESMQ 1827
              +E+E++ E+EE+  + EE+  G+EE    +EE+   +E+  W   G   +   QE   
Sbjct: 782  KMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMW---GQEEKMWGQEEKM 838

Query: 1828 W-----QWQQQLNVMVKEEQEQDEKEAIR 1851
            W      W Q+  +   EE+ Q ++E +R
Sbjct: 839  WGQEEKMWGQEEKM---EEKMQGQEEKMR 864



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 46/219 (21%), Positives = 98/219 (44%), Gaps = 15/219 (6%)

Query: 1642 ELPKRKAPREESETSEEKSPNKWGPVSKQKKQLLVDILTTIIRGLLEDKNFHEAV---DQ 1698
            E  +R   +EE    +EK    W  V K +++  +       R   E     E +   ++
Sbjct: 401  EQDERLREKEERMREQEKM---WEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREK 457

Query: 1699 SLVEQVPYFRQF---WNEQSTKFMDQKNSLYLMPILPVPSSS-WEDGKGKQPKEDRPEHY 1754
             + E+    R+      +Q     +Q+   +    LP      WE  K ++ +E   E  
Sbjct: 458  KMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQE 517

Query: 1755 PGLGKKEE--GEEEKGEEEEEELEEEE---EEEEETEEEELGKEEIEEKEEERDEKEEKV 1809
              +  +EE  G+E+K   +E+  E+E+   E+EE+  ++E    + EE+ E++ +++EK 
Sbjct: 518  EKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKK 577

Query: 1810 SWAGIGPTPQPESQESMQWQWQQQLNVMVKEEQEQDEKE 1848
            +W       + E     + + +++  +M ++E++  E+E
Sbjct: 578  TWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQE 616



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 45/204 (22%), Positives = 95/204 (46%), Gaps = 16/204 (7%)

Query: 1652 ESETSEEKSPNKWGPVSKQKKQLLVDILTTIIRGLLEDKNFHEAVDQSLVEQVPYFRQ-- 1709
            E E  E+K+  +      Q+K    + +    + + E++      ++ + EQ    ++  
Sbjct: 688  EQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQE 747

Query: 1710 --FWNEQSTKFMDQKNSLYLMPILPVPSSS-WEDGKGKQPKE--DRPEHYPGLGKKEEGE 1764
               W EQ  K  +Q+  ++    LP      WE  K ++ ++  ++ E      +K  G+
Sbjct: 748  EEMW-EQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQ 806

Query: 1765 EEKGEEEEEELEEEEEEEEETEEEELGKEE-IEEKEEERDEKEEKVSWAGIGPTPQPESQ 1823
            EEK   +EE++  +EE+    EE+  G+EE +  +EE+   +EEK+         + + Q
Sbjct: 807  EEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKME-------EKMQGQ 859

Query: 1824 ESMQWQWQQQLNVMVKEEQEQDEK 1847
            E    + ++++    ++ +EQ+EK
Sbjct: 860  EEKMREQEEKMRGQEEKMREQEEK 883



 Score = 45.8 bits (107), Expect = 4e-04
 Identities = 45/205 (21%), Positives = 97/205 (47%), Gaps = 21/205 (10%)

Query: 1650 REESETSEEKSPNKWGPVSKQKKQLLVDILTTIIRGLLEDKNFHEAVDQSLVEQVPYFRQ 1709
            R E +T E++    W    K +++   + +    + + E++      ++ + EQ    ++
Sbjct: 566  RMEKKTQEQEKKT-WDQEEKMREE---ERMREREKKMREEEEMMREQEEKMQEQEEKMQE 621

Query: 1710 ----FWNEQSTKFMDQKNSLYLMP--ILPVPSSSWEDGKGKQPKEDRPEHYPGLGKKEEG 1763
                 W EQ  K  +Q+  ++     +       WE  +  + KE   EH     +++  
Sbjct: 622  QEEKMW-EQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQ 680

Query: 1764 EEEKGEEEEEELEEE-EEEEEETEEEELGKEEIEEKEEERDEKEEKVSWAGIGPTPQPES 1822
            E+E+   E+E++E++ +E+E++T ++E  +EE   +E E+  +EE+            E 
Sbjct: 681  EQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEE--------EMMREQ 732

Query: 1823 QESMQWQWQQQLNVMVKEEQEQDEK 1847
            +E MQ Q ++++    +E  EQ+EK
Sbjct: 733  EEKMQEQ-EEKMQEQEEEMWEQEEK 756



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 31/124 (25%), Positives = 70/124 (56%), Gaps = 12/124 (9%)

Query: 1739 EDGKGKQPKEDRPEHYPGLGKKEEG---EEEKGEEEEEELEEEEEEEEE-----TEEEEL 1790
            ++ K ++ +E   E    + ++EE    +EEK  E+EE++ E+EE+  E      ++E+L
Sbjct: 608  QEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKL 667

Query: 1791 GKEEIEEKEEERDEKEEKVSWAGIGPTPQPESQESMQW---QWQQQLNVMVKEEQEQDEK 1847
             + E  +++E+  E+EEK+ W       + + QE   W   + +++ ++  +E++ ++E+
Sbjct: 668  WEHEKMQEQEKMQEQEEKI-WEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEE 726

Query: 1848 EAIR 1851
            E +R
Sbjct: 727  EMMR 730



 Score = 39.3 bits (90), Expect = 0.038
 Identities = 25/133 (18%), Positives = 63/133 (47%), Gaps = 5/133 (3%)

Query: 1744 KQPKEDRPEHYPGLGKKEEGEEEKGEEEEEELEEE-----EEEEEETEEEELGKEEIEEK 1798
            +Q +E   + +    K  E EE+   +EE   E+E     +E++   +EE + +++   +
Sbjct: 348  EQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLR 407

Query: 1799 EEERDEKEEKVSWAGIGPTPQPESQESMQWQWQQQLNVMVKEEQEQDEKEAIRRLPAFAN 1858
            E+E   +E++  W  +    + +  +  + + + Q   M +EE+ ++ ++ +R       
Sbjct: 408  EKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMR 467

Query: 1859 LQEALLENMIQNI 1871
             QE  ++   +N+
Sbjct: 468  EQEEKMQKQEENM 480



 Score = 36.6 bits (83), Expect = 0.24
 Identities = 16/36 (44%), Positives = 26/36 (72%)

Query: 1759 KKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEE 1794
            +K +G+EEK  E+EE++  +EE+  E EE+  G+EE
Sbjct: 854  EKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEE 889


>gi|189409130 zinc finger E-box binding homeobox 1 isoform a [Homo
            sapiens]
          Length = 1108

 Score = 55.8 bits (133), Expect = 4e-07
 Identities = 40/116 (34%), Positives = 60/116 (51%), Gaps = 15/116 (12%)

Query: 1741 GKGKQPKEDRPEHYPGLGKKEEGEEEKGEEEE----EELEEEEE-------EEEETEEEE 1789
            G    P +   +    L ++E+ + EK EEEE    EEL+EE+E       EEEE EEEE
Sbjct: 996  GARASPSQGDSDERESLTREEDEDSEKEEEEEDKEMEELQEEKECEKPQGDEEEEEEEEE 1055

Query: 1790 LGKEEIEEKEEERDEKEEKVSWAGIGPTPQPESQESMQWQWQQQLNVMVKEEQEQD 1845
            + +EE+EE E E +E + +    G+    + ESQ S   Q   + +  V EE+  +
Sbjct: 1056 VEEEEVEEAENEGEEAKTE----GLMKDDRAESQASSLGQKVGESSEQVSEEKTNE 1107



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 31/88 (35%), Positives = 49/88 (55%), Gaps = 2/88 (2%)

Query: 1739 EDGKGKQPKEDRPEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEK 1798
            ED   ++ +E+  +    L +++E E+ +G+EEEEE EEE EEEE  E E  G+E   E 
Sbjct: 1016 EDEDSEKEEEEEDKEMEELQEEKECEKPQGDEEEEEEEEEVEEEEVEEAENEGEEAKTEG 1075

Query: 1799 EEERDEKEEKVSWAG--IGPTPQPESQE 1824
              + D  E + S  G  +G + +  S+E
Sbjct: 1076 LMKDDRAESQASSLGQKVGESSEQVSEE 1103



 Score = 38.5 bits (88), Expect = 0.064
 Identities = 29/82 (35%), Positives = 45/82 (54%), Gaps = 6/82 (7%)

Query: 1735 SSSWEDGKGKQPKEDRPEHYPGLGKKEEGEEEKGEE-EEEELEEEEEEEEETEEEELGKE 1793
            S   E+ + K+ +E + E      + +E EEE+ EE EEEE+EE E E EE + E L K+
Sbjct: 1020 SEKEEEEEDKEMEELQEEKECEKPQGDEEEEEEEEEVEEEEVEEAENEGEEAKTEGLMKD 1079

Query: 1794 EIEEKE-----EERDEKEEKVS 1810
            +  E +     ++  E  E+VS
Sbjct: 1080 DRAESQASSLGQKVGESSEQVS 1101



 Score = 33.5 bits (75), Expect = 2.1
 Identities = 27/100 (27%), Positives = 44/100 (44%), Gaps = 21/100 (21%)

Query: 1760 KEEGEEEKGEEEEEELEEEEEEE-----------EETEEEELGKEEIEEKEEERDEKEEK 1808
            K E EE    E+EE   E    E           +  E E L +EE E+ E+E +E++++
Sbjct: 971  KREAEERDSTEQEEAGPEILSNEHVGARASPSQGDSDERESLTREEDEDSEKEEEEEDKE 1030

Query: 1809 VSWAGIGPTPQPESQESMQWQWQQQLNVMVKEEQEQDEKE 1848
            +           E QE  + +  Q      +EE+E +E+E
Sbjct: 1031 ME----------ELQEEKECEKPQGDEEEEEEEEEVEEEE 1060


>gi|189409128 zinc finger E-box binding homeobox 1 isoform b [Homo
            sapiens]
          Length = 1124

 Score = 55.8 bits (133), Expect = 4e-07
 Identities = 40/116 (34%), Positives = 60/116 (51%), Gaps = 15/116 (12%)

Query: 1741 GKGKQPKEDRPEHYPGLGKKEEGEEEKGEEEE----EELEEEEE-------EEEETEEEE 1789
            G    P +   +    L ++E+ + EK EEEE    EEL+EE+E       EEEE EEEE
Sbjct: 1012 GARASPSQGDSDERESLTREEDEDSEKEEEEEDKEMEELQEEKECEKPQGDEEEEEEEEE 1071

Query: 1790 LGKEEIEEKEEERDEKEEKVSWAGIGPTPQPESQESMQWQWQQQLNVMVKEEQEQD 1845
            + +EE+EE E E +E + +    G+    + ESQ S   Q   + +  V EE+  +
Sbjct: 1072 VEEEEVEEAENEGEEAKTE----GLMKDDRAESQASSLGQKVGESSEQVSEEKTNE 1123



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 31/88 (35%), Positives = 49/88 (55%), Gaps = 2/88 (2%)

Query: 1739 EDGKGKQPKEDRPEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEK 1798
            ED   ++ +E+  +    L +++E E+ +G+EEEEE EEE EEEE  E E  G+E   E 
Sbjct: 1032 EDEDSEKEEEEEDKEMEELQEEKECEKPQGDEEEEEEEEEVEEEEVEEAENEGEEAKTEG 1091

Query: 1799 EEERDEKEEKVSWAG--IGPTPQPESQE 1824
              + D  E + S  G  +G + +  S+E
Sbjct: 1092 LMKDDRAESQASSLGQKVGESSEQVSEE 1119



 Score = 38.5 bits (88), Expect = 0.064
 Identities = 29/82 (35%), Positives = 45/82 (54%), Gaps = 6/82 (7%)

Query: 1735 SSSWEDGKGKQPKEDRPEHYPGLGKKEEGEEEKGEE-EEEELEEEEEEEEETEEEELGKE 1793
            S   E+ + K+ +E + E      + +E EEE+ EE EEEE+EE E E EE + E L K+
Sbjct: 1036 SEKEEEEEDKEMEELQEEKECEKPQGDEEEEEEEEEVEEEEVEEAENEGEEAKTEGLMKD 1095

Query: 1794 EIEEKE-----EERDEKEEKVS 1810
            +  E +     ++  E  E+VS
Sbjct: 1096 DRAESQASSLGQKVGESSEQVS 1117



 Score = 33.5 bits (75), Expect = 2.1
 Identities = 27/100 (27%), Positives = 44/100 (44%), Gaps = 21/100 (21%)

Query: 1760 KEEGEEEKGEEEEEELEEEEEEE-----------EETEEEELGKEEIEEKEEERDEKEEK 1808
            K E EE    E+EE   E    E           +  E E L +EE E+ E+E +E++++
Sbjct: 987  KREAEERDSTEQEEAGPEILSNEHVGARASPSQGDSDERESLTREEDEDSEKEEEEEDKE 1046

Query: 1809 VSWAGIGPTPQPESQESMQWQWQQQLNVMVKEEQEQDEKE 1848
            +           E QE  + +  Q      +EE+E +E+E
Sbjct: 1047 ME----------ELQEEKECEKPQGDEEEEEEEEEVEEEE 1076


>gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isoform 3
            [Homo sapiens]
          Length = 526

 Score = 55.8 bits (133), Expect = 4e-07
 Identities = 33/75 (44%), Positives = 43/75 (57%), Gaps = 6/75 (8%)

Query: 1735 SSSWEDGKGKQPKEDRPEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEE 1794
            SSS E G G + +E+  E      ++EEG   +  EEEEE EEEEEEE  +  EE  ++ 
Sbjct: 25   SSSAESGSGSEEEEEEEEE-----EEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQS 79

Query: 1795 IEE-KEEERDEKEEK 1808
             EE  EEE  E EE+
Sbjct: 80   AEEVSEEEMSEDEER 94



 Score = 51.6 bits (122), Expect = 7e-06
 Identities = 35/110 (31%), Positives = 49/110 (44%), Gaps = 9/110 (8%)

Query: 1740 DGKGKQPKEDRPEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKE 1799
            D + K    +      G G +EE EEE+ EEEE    EE EEEEE EEEE         E
Sbjct: 15   DSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEE---------E 65

Query: 1800 EERDEKEEKVSWAGIGPTPQPESQESMQWQWQQQLNVMVKEEQEQDEKEA 1849
            EE     E+ S        + E  E  + + +  L V+ +   ++D  E+
Sbjct: 66   EETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGES 115



 Score = 51.6 bits (122), Expect = 7e-06
 Identities = 31/96 (32%), Positives = 52/96 (54%), Gaps = 9/96 (9%)

Query: 1759 KKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEKVSWAGIGPTP 1818
            +K    E    E     EEEEEEEEE EEE    EE EE+EEE +E+EE+      G   
Sbjct: 18   RKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEET-----GSNS 72

Query: 1819 QPESQESMQWQWQQQLNVMVKEEQEQDEKEAIRRLP 1854
            +  S++S +   +++++    E++E++ +  +  +P
Sbjct: 73   EEASEQSAEEVSEEEMS----EDEERENENHLLVVP 104


>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
            [Homo sapiens]
          Length = 2073

 Score = 55.5 bits (132), Expect = 5e-07
 Identities = 30/56 (53%), Positives = 37/56 (66%)

Query: 1751 PEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKE 1806
            PE  P  G++ +  E   E  EEE EEE+EEEEE EEEE   EE EE+EEE +E+E
Sbjct: 1049 PESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEE 1104



 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 28/51 (54%), Positives = 34/51 (66%)

Query: 1760 KEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEKVS 1810
            +EE EEE  EEEEEE EEEE+EEEE EEEE  +EE  +    R  K + V+
Sbjct: 1070 EEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVA 1120



 Score = 49.3 bits (116), Expect = 4e-05
 Identities = 24/38 (63%), Positives = 31/38 (81%)

Query: 1759 KKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIE 1796
            ++EE EE++ EEEEEE EEE+EEEEE EEEE  +E I+
Sbjct: 1070 EEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQ 1107



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 36/119 (30%), Positives = 59/119 (49%), Gaps = 24/119 (20%)

Query: 1739 EDGKGKQPKEDR----------PEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETEEE 1788
            E G+   P+E+           P   PG   +++  + + EEEEEE EEEEEEEEE EEE
Sbjct: 1313 ETGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEE 1372

Query: 1789 ELGKEEIEEKEEERDEKEEKVSWAGIGPTPQPESQESMQWQWQQQLNVMVKEEQEQDEK 1847
            E G    ++ +  + +++E+       P    E ++S +    +       EE+E+DE+
Sbjct: 1373 EGGGNVEKDPDGAKSQEKEE-------PEISTEKEDSARLDDHE-------EEEEEDEE 1417



 Score = 45.1 bits (105), Expect = 7e-04
 Identities = 27/54 (50%), Positives = 34/54 (62%), Gaps = 1/54 (1%)

Query: 1766 EKGEEEEEELEE-EEEEEEETEEEELGKEEIEEKEEERDEKEEKVSWAGIGPTP 1818
            E+G+  E   E  EEEEEEE EEEE  +EE EE EEE +E+EE+     I  +P
Sbjct: 1057 ERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSP 1110



 Score = 42.0 bits (97), Expect = 0.006
 Identities = 22/38 (57%), Positives = 26/38 (68%)

Query: 1747 KEDRPEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEE 1784
            KE   E      ++EE EEE+ EE+EEE EEEEEEEEE
Sbjct: 1066 KESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEE 1103



 Score = 41.2 bits (95), Expect = 0.010
 Identities = 26/81 (32%), Positives = 44/81 (54%), Gaps = 3/81 (3%)

Query: 1768 GEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEKVSWAGIGPTPQPESQESMQ 1827
            GE+ E++L + EEEEEE   EE  +EE EE+E E +E    V     G   Q + +  + 
Sbjct: 1340 GEKPEDDLIKPEEEEEE---EEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEIS 1396

Query: 1828 WQWQQQLNVMVKEEQEQDEKE 1848
             + +    +   EE+E++++E
Sbjct: 1397 TEKEDSARLDDHEEEEEEDEE 1417



 Score = 40.8 bits (94), Expect = 0.013
 Identities = 21/39 (53%), Positives = 26/39 (66%)

Query: 1744 KQPKEDRPEHYPGLGKKEEGEEEKGEEEEEELEEEEEEE 1782
            K+  E+  E      ++EE EEE+ EEEEEE EEEEEEE
Sbjct: 1066 KESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEE 1104



 Score = 40.0 bits (92), Expect = 0.022
 Identities = 24/58 (41%), Positives = 33/58 (56%), Gaps = 5/58 (8%)

Query: 1737 SWEDGKGKQPKEDRPEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEE 1794
            S E  + ++ +ED  E      ++EE EEE  EEEEEE EEEEEE  ++    L K +
Sbjct: 1065 SKESSEEEEEEEDEEEE-----EEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQ 1117



 Score = 37.0 bits (84), Expect = 0.19
 Identities = 31/101 (30%), Positives = 43/101 (42%), Gaps = 41/101 (40%)

Query: 1743 GKQPKED--RPEHYPGLGKKEEGEEEKGEEEEEELEEEE--------------------- 1779
            G++P++D  +PE      ++EE EEE+ EEEEEE EEEE                     
Sbjct: 1340 GEKPEDDLIKPEE-----EEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPE 1394

Query: 1780 -------------EEEEETEEEELGKEEIEEKEEERDEKEE 1807
                          EEEE E+EE    E  + ++E D   E
Sbjct: 1395 ISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHME 1435



 Score = 34.3 bits (77), Expect = 1.2
 Identities = 22/68 (32%), Positives = 31/68 (45%), Gaps = 7/68 (10%)

Query: 1740 DGKGKQPKEDRPEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKE 1799
            DG   Q KE+     P +  ++E      + EEEE  EE+EE    E+ +   E+    E
Sbjct: 1383 DGAKSQEKEE-----PEISTEKEDSARLDDHEEEE--EEDEEPSHNEDHDADDEDDSHME 1435

Query: 1800 EERDEKEE 1807
                EKEE
Sbjct: 1436 SAEVEKEE 1443



 Score = 33.9 bits (76), Expect = 1.6
 Identities = 19/78 (24%), Positives = 38/78 (48%)

Query: 1730 ILPVPSSSWEDGKGKQPKEDRPEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETEEEE 1789
            I P      E+ + ++ +E+  E   G G  E+  +    +E+EE E   E+E+    ++
Sbjct: 1348 IKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDD 1407

Query: 1790 LGKEEIEEKEEERDEKEE 1807
              +EE E++E   +E  +
Sbjct: 1408 HEEEEEEDEEPSHNEDHD 1425



 Score = 32.0 bits (71), Expect = 6.0
 Identities = 15/48 (31%), Positives = 29/48 (60%), Gaps = 3/48 (6%)

Query: 1759 KKEEGEEEKGEEEEEELEEEEE---EEEETEEEELGKEEIEEKEEERD 1803
            ++EE +EE    E+ + ++E++   E  E E+EEL +E  +E  E ++
Sbjct: 1410 EEEEEDEEPSHNEDHDADDEDDSHMESAEVEKEELPRESFKEVLENQE 1457


>gi|84043963 eukaryotic translation initiation factor 5B [Homo
            sapiens]
          Length = 1220

 Score = 55.1 bits (131), Expect = 7e-07
 Identities = 46/131 (35%), Positives = 60/131 (45%), Gaps = 9/131 (6%)

Query: 1760 KEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEKVSWAGIGPTPQ 1819
            KE  EEE+ EEEEEE +EE EEEEE E E  G E  EE E+  DEK+   S   +   P 
Sbjct: 528  KENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKD---SGKTLDKKPS 584

Query: 1820 PESQESMQWQWQQQLNVMVKEEQEQDE-KEAI--RRLPAFANLQEALLENMIQNILVEAS 1876
             E     ++          KEE+  D+ K  I  RRL    N+    L   I  +L    
Sbjct: 585  KEMSSDSEYDSDDD---RTKEERAYDKAKRRIEKRRLEHSKNVNTEKLRAPIICVLGHVD 641

Query: 1877 RGEVVLTSRPR 1887
             G+  +  + R
Sbjct: 642  TGKTKILDKLR 652



 Score = 44.7 bits (104), Expect = 9e-04
 Identities = 31/89 (34%), Positives = 53/89 (59%), Gaps = 17/89 (19%)

Query: 1734 PSSSWEDGKGKQPKEDRPEHYPGLGKKEEGEEEKG-----------EEEEEELEEEEEEE 1782
            P+++ +D +G + K+D+ +     G+KEE E+EK            +E   +L+EEEE +
Sbjct: 302  PTAAEDDNEGDKKKKDKKKKK---GEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQ 358

Query: 1783 EETEEEELGK-EEIE--EKEEERDEKEEK 1808
            +  EEE + + EE+E   KEEER E+E++
Sbjct: 359  KREEEERIKRLEELEAKRKEEERLEQEKR 387



 Score = 43.1 bits (100), Expect = 0.003
 Identities = 31/118 (26%), Positives = 61/118 (51%), Gaps = 4/118 (3%)

Query: 1760 KEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEKVSWAGIGPTPQ 1819
            KEE E +K EEEE     EE E +  EEE L +E+ E K+++  E++E++   G   T  
Sbjct: 352  KEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLT-- 409

Query: 1820 PESQESMQWQWQQQLNVMVKEEQEQDEKEAI-RRLPAFANLQEALLENMIQNILVEAS 1876
             +SQ   + + +  L ++  +  E   K+++ ++ P + + +   +   +++  V  S
Sbjct: 410  -KSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSES 466



 Score = 36.2 bits (82), Expect = 0.32
 Identities = 29/116 (25%), Positives = 63/116 (54%), Gaps = 20/116 (17%)

Query: 1748 EDRPEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETE----------EEELGKEEIEE 1797
            E++ E         EG+++K ++++++ E+EE+E+E+ +          +E L K + EE
Sbjct: 296  EEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLK-EE 354

Query: 1798 KEEERDEKEEKVSWAGIGPTPQPESQESMQWQWQQQLNVMVKEEQEQDEKEAIRRL 1853
            +E ++ E+EE++         + E  E+ + + +++L    +E ++Q EKE   RL
Sbjct: 355  EERQKREEEERIK--------RLEELEAKRKE-EERLEQEKRERKKQKEKERKERL 401



 Score = 34.3 bits (77), Expect = 1.2
 Identities = 32/128 (25%), Positives = 57/128 (44%), Gaps = 31/128 (24%)

Query: 1757 LGKKEEGE-----EEKGEEEEEELEEE---------------EEEEEET----EEEELGK 1792
            L +KEE E     + K +E + + EEE                EE+ ET    E++  G 
Sbjct: 253  LKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGD 312

Query: 1793 EEIEEKEEERDEKEEKVSWAGIGPTPQPESQESMQWQWQQQLNVMVKEEQEQDEKEAIRR 1852
            ++ ++K++++ EKEEK      GP+              Q+    +KEE+E+ ++E   R
Sbjct: 313  KKKKDKKKKKGEKEEKEKEKKKGPSKATVKA-------MQEALAKLKEEEERQKREEEER 365

Query: 1853 LPAFANLQ 1860
            +     L+
Sbjct: 366  IKRLEELE 373



 Score = 33.9 bits (76), Expect = 1.6
 Identities = 33/120 (27%), Positives = 62/120 (51%), Gaps = 20/120 (16%)

Query: 1759 KKEEGEEEKGEEEEEELEEEEEEEE-ETEEEELGKEEIEEKEEERDEKEEKVSW-----A 1812
            +K+E E +K +EE+ +L + +E+EE ET +    K++ ++KE +R  +EE V        
Sbjct: 234  EKKERERKKRDEEKAKLRKLKEKEELETGK----KDQSKQKESQRKFEEETVKSKVTVDT 289

Query: 1813 GI---------GPTPQPESQESMQWQWQQQLNVMVKEEQEQDEKEAIRRLPAFANLQEAL 1863
            G+          PT   +  E  + +  ++     KEE+E+++K+   +    A +QEAL
Sbjct: 290  GVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKA-MQEAL 348


>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
            sapiens]
          Length = 750

 Score = 54.7 bits (130), Expect = 9e-07
 Identities = 52/214 (24%), Positives = 91/214 (42%), Gaps = 33/214 (15%)

Query: 1650 REESETSEEKSPNKWGPVSKQKKQLLVDILTTIIRGLLEDKNFHEAVDQSLVEQVPYFRQ 1709
            RE+ E   E+    W    K ++Q  +           E++  HE              +
Sbjct: 520  REQEEKIREQEEKMWRQEEKIREQEEM---------WREEEKMHEQ------------EK 558

Query: 1710 FWNEQSTKFMDQKNSLYLMPILPVPSSSW-EDGKGKQPKEDRPEHYPGLGKKEEGEEEKG 1768
             W E+  +  + K       I       W ++ K ++ +E R E    + K    +EEK 
Sbjct: 559  IWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWK----QEEKI 614

Query: 1769 EEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEKVSWAGIGPTPQPES-QESMQ 1827
             E+EE+++E+EE+  E EE+      I E+EE   E+EEK+         Q E  QE  +
Sbjct: 615  REQEEKIQEQEEKIREQEEK------IREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEE 668

Query: 1828 WQWQQQLNVMVKEEQEQDEKEAIRRLPAFANLQE 1861
              W+Q+  +  +E++ ++++E IR        QE
Sbjct: 669  TMWRQEEKIREQEKKIREQEEKIREQEEMMQEQE 702



 Score = 53.1 bits (126), Expect = 3e-06
 Identities = 31/101 (30%), Positives = 59/101 (58%), Gaps = 5/101 (4%)

Query: 1765 EEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEKVSWAGIGPTPQPESQE 1824
            EEK +E+EE++ E+EE+  E EE+   +EE+  ++EE+  ++E++ W       +   QE
Sbjct: 313  EEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWE---KEEKMRRQE 369

Query: 1825 SMQWQWQQQLNVMVKEEQEQDEKEAIRRLPAFANLQEALLE 1865
             M W+ ++++    +EE   +++E IR L    + QE + E
Sbjct: 370  EMMWEKEEKMR--RQEEMMWEKEEKIRELEEKMHEQEKIRE 408



 Score = 50.4 bits (119), Expect = 2e-05
 Identities = 39/116 (33%), Positives = 64/116 (55%), Gaps = 19/116 (16%)

Query: 1747 KEDRPEHYPGLGKKEEG---EEEKGEEEEEELEEEEE-----EEEETEEEELGKEE---- 1794
            KE   E    + K+EE    +EEK  E+EE++ E+EE     EE+  E+EE+ +EE    
Sbjct: 495  KEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMH 554

Query: 1795 IEEK---EEERDEKEEKVSWAGIGPTPQPESQESMQWQWQQQLNVMVKEEQEQDEK 1847
             +EK   EE+R E+E+K+ W       +   QE   W+ ++++    ++ QEQ+EK
Sbjct: 555  EQEKIWEEEKRQEQEDKM-WR---QEEKIREQEEKVWRQEEKIREQEEKRQEQEEK 606



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 27/93 (29%), Positives = 53/93 (56%), Gaps = 6/93 (6%)

Query: 1759 KKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEKVSWAGIGPTP 1818
            +K   +EEK  E+EE++  +EE   E EE+   +EE+  ++EE+  ++E++ W       
Sbjct: 321  EKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWE---KEE 377

Query: 1819 QPESQESMQWQWQQQLNVMVKEEQEQDEKEAIR 1851
            +   QE M W+ ++++  +   E++  E+E IR
Sbjct: 378  KMRRQEEMMWEKEEKIREL---EEKMHEQEKIR 407



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 36/120 (30%), Positives = 63/120 (52%), Gaps = 14/120 (11%)

Query: 1759 KKEEGEEEKGEEEEEELEEEE---EEEEETEEEELGKEEIEEKEEER--------DEKEE 1807
            K  E EE+   +EE+  E+EE   EEE+  E+E++ +EE  +++E++         E+EE
Sbjct: 525  KIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEE 584

Query: 1808 KVSWAGIGPTPQPES--QESMQWQWQQQLNVMVKEEQEQDEKEAIRRLPAFANLQEALLE 1865
            KV W       + E   QE  +  W+Q+  +  +EE+ Q+++E IR        QE + +
Sbjct: 585  KV-WRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQ 643



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 37/134 (27%), Positives = 73/134 (54%), Gaps = 9/134 (6%)

Query: 1738 WE-DGKGKQPKEDRPEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEE-TEEEELGKEEI 1795
            WE + K ++ +E   E    + ++EE   EK EE+  ELEE+  E+E+  E+EE  +EE 
Sbjct: 359  WEKEEKMRRQEEMMWEKEEKMRRQEEMMWEK-EEKIRELEEKMHEQEKIREQEEKRQEEE 417

Query: 1796 EEKEEERDEKEEKVSWAGIGPTPQPE----SQESMQWQWQQQLNVM--VKEEQEQDEKEA 1849
            + +E+E+ +++E   W       + E     QE   W+ +++++    ++EE+++ E+E 
Sbjct: 418  KIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEE 477

Query: 1850 IRRLPAFANLQEAL 1863
            + R     + QE +
Sbjct: 478  MWRQEEKIHEQEEI 491



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 31/99 (31%), Positives = 56/99 (56%), Gaps = 8/99 (8%)

Query: 1759 KKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEKVSWAGIGPTP 1818
            ++E+  EE+  +E+EE+  +EE+  E EE    KE++ E+EE+  ++EEKV W       
Sbjct: 462  EQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKV-WRQEEKIR 520

Query: 1819 QPE----SQESMQWQWQQQL---NVMVKEEQEQDEKEAI 1850
            + E     QE   W+ ++++     M +EE++  E+E I
Sbjct: 521  EQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKI 559



 Score = 45.8 bits (107), Expect = 4e-04
 Identities = 29/109 (26%), Positives = 57/109 (52%), Gaps = 11/109 (10%)

Query: 1739 EDGKGKQPKEDRPEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEK 1798
            ++ K ++ +E   E    + ++EE   E+ +  EEE  +E+EE    EE+   +EEI  +
Sbjct: 435  QEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQ 494

Query: 1799 EEERDEKEEKVSWAGIGPTPQPESQESMQWQWQQQLNVMVKEEQEQDEK 1847
            +E+  E+EEK+             QE   W+ ++++    ++ +EQ+EK
Sbjct: 495  KEKMHEQEEKI-----------RKQEEKVWRQEEKIREQEEKIREQEEK 532



 Score = 45.1 bits (105), Expect = 7e-04
 Identities = 39/163 (23%), Positives = 73/163 (44%), Gaps = 23/163 (14%)

Query: 1650 REESETSEEKSPNKWGPVSKQKKQL-LVDILTTIIRGLLEDKNFHEAVDQSLVEQVPYFR 1708
            RE+ E  +E+    W    K ++Q   +      IR   E     E + Q   E++    
Sbjct: 594  REQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQE 653

Query: 1709 QFWNEQSTKFMDQKNSLYLMPILPVPSSSWEDGKGKQPKEDRPEHYPGLGKKEEGEEEKG 1768
            +   EQ  K  +Q+ +++                 +Q ++ R +      KK   +EEK 
Sbjct: 654  EKMCEQEEKMQEQEETMW-----------------RQEEKIREQE-----KKIREQEEKI 691

Query: 1769 EEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEKVSW 1811
             E+EE ++E+EE+  E EE+   +EE  +++EE+  ++E+  W
Sbjct: 692  REQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMW 734



 Score = 43.1 bits (100), Expect = 0.003
 Identities = 35/154 (22%), Positives = 75/154 (48%), Gaps = 20/154 (12%)

Query: 1698 QSLVEQVPYFRQFWNEQSTKFMDQKNSLYLMPILPVPSSSWEDGKGKQPKEDRPEHYPGL 1757
            Q+ VE+   + +   +Q  K   Q+  +            WE+ K ++ +E   E    +
Sbjct: 282  QAQVEENELWNRLNQQQEEKMWRQEEKI----------QEWEE-KIQEQEEKIREQEEKI 330

Query: 1758 GKKEEG---EEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEKVSWAGI 1814
             ++EE    +EE   E+EE++  +EE   E EE+   +EE+  ++EE+  ++E++ W   
Sbjct: 331  REQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMW--- 387

Query: 1815 GPTPQPESQESMQWQWQQQLNVMVKEEQEQDEKE 1848
                + E    ++ +  +Q  +  +EE+ Q+E++
Sbjct: 388  ---EKEEKIRELEEKMHEQEKIREQEEKRQEEEK 418



 Score = 43.1 bits (100), Expect = 0.003
 Identities = 30/125 (24%), Positives = 59/125 (47%), Gaps = 12/125 (9%)

Query: 1759 KKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEKVSWAGIGPTP 1818
            K  + EE+   +EE+  E+EE+  E+ E+    +E+I E+EE   E+E+      I    
Sbjct: 504  KIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEE 563

Query: 1819 QPESQESMQWQ------------WQQQLNVMVKEEQEQDEKEAIRRLPAFANLQEALLEN 1866
            + + QE   W+            W+Q+  +  +EE+ Q+++E + +       QE  ++ 
Sbjct: 564  KRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQE 623

Query: 1867 MIQNI 1871
              + I
Sbjct: 624  QEEKI 628



 Score = 42.4 bits (98), Expect = 0.004
 Identities = 35/113 (30%), Positives = 59/113 (52%), Gaps = 14/113 (12%)

Query: 1759 KKEEGEEEKGEEEEEELEEEE---EEEE---ETEEEELGKEEIEEKEEERDEKEEKVSWA 1812
            K    EE   E+EE+   +EE   E+EE   E EE+   +E+I E+EE+R E EEK+   
Sbjct: 364  KMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQE-EEKI--- 419

Query: 1813 GIGPTPQPESQESMQWQWQQQLNVMVKEEQEQDEKEAIRRLPAFANLQEALLE 1865
                  Q + QE     W+Q+  +  +EE+ +++++ + R     + QE + E
Sbjct: 420  ----REQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIRE 468



 Score = 39.3 bits (90), Expect = 0.038
 Identities = 31/107 (28%), Positives = 63/107 (58%), Gaps = 10/107 (9%)

Query: 1747 KEDRPEHYPGLGKKEEGEEEKGE--EEEEELEEEEEEEEETEEEELGKEE-IEEKEEERD 1803
            +E++ +    + ++EE   E+ E   ++E++ E+EE+  + EE+   +EE I E+EE+  
Sbjct: 468  EEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIR 527

Query: 1804 EKEEKVSWAGIGPTPQPESQESMQWQWQQQLNVMVK--EEQEQDEKE 1848
            E+EEK+ W       +   QE M W+ +++++   K  EE+++ E+E
Sbjct: 528  EQEEKM-WR---QEEKIREQEEM-WREEEKMHEQEKIWEEEKRQEQE 569



 Score = 33.5 bits (75), Expect = 2.1
 Identities = 29/111 (26%), Positives = 54/111 (48%), Gaps = 6/111 (5%)

Query: 1746 PKEDRPEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEER-DE 1804
            P++        LGK+ +    K + + EE E      ++ EE+   +EE  ++ EE+  E
Sbjct: 259  PQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQE 318

Query: 1805 KEEKVSWAGIGPTPQPES---QESMQWQWQQQLNVMVKEEQEQDEKEAIRR 1852
            +EEK+         Q E    QE M W+ ++++    +EE   +++E +RR
Sbjct: 319  QEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMR--RQEEMMWEKEEKMRR 367


>gi|239745153 PREDICTED: similar to Putative golgin subfamily A member
            6-like protein 6 [Homo sapiens]
          Length = 655

 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 30/100 (30%), Positives = 60/100 (60%), Gaps = 11/100 (11%)

Query: 1748 EDRPEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEE 1807
            +D+ E    + +K + EEEK +E+EE+++ +EE+ +E EE+   +E++ ++EE+  E+EE
Sbjct: 444  QDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEE 503

Query: 1808 KVSWAGIGPTPQPESQESMQWQWQQQLNVMVKEEQEQDEK 1847
            K+ W           QE   W+ ++++    ++ Q Q+EK
Sbjct: 504  KM-W----------RQEEKMWEQEEKMQEQEEKMQRQEEK 532



 Score = 51.2 bits (121), Expect = 1e-05
 Identities = 46/174 (26%), Positives = 81/174 (46%), Gaps = 33/174 (18%)

Query: 1713 EQSTKFMDQKNSLYLMPILPVPSSSWEDGKGKQPKEDRPEHYPGLGKKEEGEEEKGEEEE 1772
            EQ  K  +Q+  ++            ++ K ++ +E R E      KK   ++EK  E+E
Sbjct: 378  EQDEKIQEQEEEMWR-----------QEEKIREQEEKRQEKMWRQEKKMREQDEKIREQE 426

Query: 1773 EELEEEEEEEEETE------EEELG--KEEIEEKEEERDEKEEKVSWAGIGPTPQPE--- 1821
            EE+  +EE+  E E      EE+L   +E+++E+EE+  E+EEK+         Q E   
Sbjct: 427  EEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTW 486

Query: 1822 ------SQESMQWQ-----WQQQLNVMVKEEQEQDEKEAIRRLPAFANLQEALL 1864
                   QE   W+     W+Q+  +  +EE+ Q+++E ++R       QE  L
Sbjct: 487  RQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRL 540



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 38/138 (27%), Positives = 70/138 (50%), Gaps = 16/138 (11%)

Query: 1739 EDGKGKQPKEDRPEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEE-IEE 1797
            ED   +Q ++ R +      +K   +EEK   +EE++ E++E+ +E EEE   +EE I E
Sbjct: 345  EDKMWRQEEKIREQE-----EKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIRE 399

Query: 1798 KEEERDEK----EEKVSWAGIGPTPQPESQESMQWQWQQQLNVMVKEEQEQDEKEAIRRL 1853
            +EE+R EK    E+K+           + +E  +  W+Q+  +   EE  QD++E +R +
Sbjct: 400  QEEKRQEKMWRQEKKMR------EQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREV 453

Query: 1854 PAFANLQEALLENMIQNI 1871
                  +E  ++   + I
Sbjct: 454  EEKMQEEEEKMQEQEEKI 471



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 35/123 (28%), Positives = 65/123 (52%), Gaps = 19/123 (15%)

Query: 1764 EEEKGEEEEEELEEEEE----EEEETEEEELGKEEIEEKEEERDEKEEKVSWAGIGPTPQ 1819
            +EEK  E+EE++ E+EE    +EE+  E++   E+I+E+EEE   +EEK+         Q
Sbjct: 351  QEEKIREQEEKIREQEEKMWRQEEKIREQD---EKIQEQEEEMWRQEEKI-------REQ 400

Query: 1820 PESQESMQWQWQQQLNVMVKEEQEQDE-----KEAIRRLPAFANLQEALLENMIQNILVE 1874
             E ++   W+ ++++    ++ +EQ+E     +E IR L      QE  L  + + +  E
Sbjct: 401  EEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEE 460

Query: 1875 ASR 1877
              +
Sbjct: 461  EEK 463



 Score = 45.1 bits (105), Expect = 7e-04
 Identities = 29/85 (34%), Positives = 50/85 (58%), Gaps = 2/85 (2%)

Query: 1764 EEEKGEEEEEELEEEEEEEEETEEEELGKEE-IEEKEEERDEKEEKVSWAGIGPTPQPES 1822
            +EEK   +EE++ E+EE+  E E++   +EE I E+EE+  E+EEK+         Q E 
Sbjct: 323  QEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEK 382

Query: 1823 -QESMQWQWQQQLNVMVKEEQEQDE 1846
             QE  +  W+Q+  +  +EE+ Q++
Sbjct: 383  IQEQEEEMWRQEEKIREQEEKRQEK 407



 Score = 45.1 bits (105), Expect = 7e-04
 Identities = 48/212 (22%), Positives = 96/212 (45%), Gaps = 26/212 (12%)

Query: 1645 KRKAPREESETSEEKSPNKWGPVSKQKKQLLVDILTTIIRGLLEDKNFHEAVDQSLVEQV 1704
            + K  RE+ E   E+    W    ++K + L +++      L E +   +  ++ + EQ 
Sbjct: 411  QEKKMREQDEKIREQEEEMWR--QEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQE 468

Query: 1705 PYFRQFWNEQSTKFMDQKNSLYLMP-ILPVPSSSWEDGKGKQPKEDRPEHYPGLGKKEEG 1763
               ++    Q  K  +Q+   +    +L      WE  +    +E++        +K + 
Sbjct: 469  EKIQR----QEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQE---EKMQE 521

Query: 1764 EEEKGEEEEEELEEEE----EEEEETEEEELGKEEIEEKEEERDEKEEKVSWAGIG---- 1815
            +EEK + +EE++ E+E    ++EE+ +E+E+  +E+EE+  +  +K E +  AG      
Sbjct: 522  QEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQ 581

Query: 1816 --PTPQPESQESMQWQWQQQLNVMVKEEQEQD 1845
              PT  P  Q  ++ Q  Q L      +Q+QD
Sbjct: 582  RLPTLTPILQVELKSQEAQSL------QQQQD 607



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 25/91 (27%), Positives = 52/91 (57%), Gaps = 2/91 (2%)

Query: 1764 EEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEKVSWAGIGPTPQPES- 1822
            +EEK +E+EE++ E+E +  E EE+   +EE   ++EE+  ++E   W       + E  
Sbjct: 302  QEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEK 361

Query: 1823 -QESMQWQWQQQLNVMVKEEQEQDEKEAIRR 1852
             +E  +  W+Q+  +  ++E+ Q+++E + R
Sbjct: 362  IREQEEKMWRQEEKIREQDEKIQEQEEEMWR 392



 Score = 41.2 bits (95), Expect = 0.010
 Identities = 28/88 (31%), Positives = 48/88 (54%), Gaps = 18/88 (20%)

Query: 1764 EEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEK----EEERDEKEEKVSWAGIGPTPQ 1819
            +EEK   +EE+++E+EE+     E+EL   E EEK    EE+  E+EEK+          
Sbjct: 295  QEEKMWRQEEKIQEQEEK---MCEQELKIREQEEKMWRQEEKMHEQEEKI---------- 341

Query: 1820 PESQESMQWQWQQQLNVMVKEEQEQDEK 1847
               QE   W+ ++++    ++ +EQ+EK
Sbjct: 342  -REQEDKMWRQEEKIREQEEKIREQEEK 368



 Score = 41.2 bits (95), Expect = 0.010
 Identities = 33/150 (22%), Positives = 78/150 (52%), Gaps = 20/150 (13%)

Query: 1712 NEQSTKFMDQKNSLYLMPILPVPSSSWEDGKGKQPKEDRPEHYPGLGKKEEG---EEEKG 1768
            +EQ  K  +Q++ ++            ++ K ++ +E   E    + ++EE    ++EK 
Sbjct: 335  HEQEEKIREQEDKMWR-----------QEEKIREQEEKIREQEEKMWRQEEKIREQDEKI 383

Query: 1769 EEEEEELEEEEE----EEEETEEEELGKEEIEEKEEERDEKEEKVSWAGIGPTPQPESQE 1824
            +E+EEE+  +EE    +EE+ +E+   +E+   +++E+  ++E+  W       + E   
Sbjct: 384  QEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMM 443

Query: 1825 SMQWQWQQQLNVMVKEEQE--QDEKEAIRR 1852
              Q +  +++   ++EE+E  Q+++E I+R
Sbjct: 444  QDQEEKLREVEEKMQEEEEKMQEQEEKIQR 473


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.134    0.416 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 84,346,994
Number of Sequences: 37866
Number of extensions: 4409247
Number of successful extensions: 80023
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 843
Number of HSP's successfully gapped in prelim test: 467
Number of HSP's that attempted gapping in prelim test: 28813
Number of HSP's gapped (non-prelim): 18560
length of query: 1925
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1808
effective length of database: 13,817,196
effective search space: 24981490368
effective search space used: 24981490368
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 70 (31.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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