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Search of human proteins with 82546830
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|82546830 SEC8 protein isoform a [Homo sapiens]
(974 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|82546830 SEC8 protein isoform a [Homo sapiens] 1896 0.0
gi|82546832 SEC8 protein isoform b [Homo sapiens] 914 0.0
gi|215982794 myosin VA isoform 2 [Homo sapiens] 48 4e-05
gi|215982791 myosin VA isoform 1 [Homo sapiens] 48 4e-05
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 44 6e-04
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 44 7e-04
gi|71061468 centromere protein E [Homo sapiens] 44 0.001
gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens] 41 0.005
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] 41 0.006
gi|118498356 kinectin 1 isoform a [Homo sapiens] 39 0.024
gi|118498368 kinectin 1 isoform c [Homo sapiens] 39 0.024
gi|33620775 kinectin 1 isoform a [Homo sapiens] 39 0.024
gi|149363642 coiled-coil domain containing 144A [Homo sapiens] 39 0.024
gi|32189362 PTPRF interacting protein alpha 3 [Homo sapiens] 38 0.053
gi|4758650 kinesin family member 5C [Homo sapiens] 37 0.069
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 37 0.090
gi|112420968 coiled-coil domain containing 158 [Homo sapiens] 37 0.090
gi|151301127 dynein, axonemal, heavy chain 7 [Homo sapiens] 37 0.12
gi|34878904 synaptonemal complex protein 1 [Homo sapiens] 37 0.12
gi|224458301 family with sequence similarity 186, member A [Homo... 36 0.15
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens] 36 0.20
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens] 36 0.20
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] 36 0.20
gi|51972208 leucine, glutamate and lysine rich 1 [Homo sapiens] 35 0.45
gi|8924258 gamma-aminobutyric acid (GABA) receptor, theta precur... 34 0.58
gi|55769583 progesterone-induced blocking factor 1 [Homo sapiens] 34 0.76
gi|109255234 centrosomal protein 290kDa [Homo sapiens] 33 1.00
gi|54792740 transmembrane and coiled-coil domain family 2 [Homo ... 33 1.00
gi|70166430 GRINL1A combined protein isoform 2 [Homo sapiens] 33 1.3
gi|70166414 GRINL1A combined protein isoform 1 [Homo sapiens] 33 1.3
>gi|82546830 SEC8 protein isoform a [Homo sapiens]
Length = 974
Score = 1896 bits (4912), Expect = 0.0
Identities = 974/974 (100%), Positives = 974/974 (100%)
Query: 1 MAAEAAGGKYRSTVSKSKDPSGLLISVIRTLSTSDDVEDRENEKGRLEEAYEKCDRDLDE 60
MAAEAAGGKYRSTVSKSKDPSGLLISVIRTLSTSDDVEDRENEKGRLEEAYEKCDRDLDE
Sbjct: 1 MAAEAAGGKYRSTVSKSKDPSGLLISVIRTLSTSDDVEDRENEKGRLEEAYEKCDRDLDE 60
Query: 61 LIVQHYTELTTAIRTYQSITERITNSRNKIKQVKENLLSCKMLLHCKRDELRKLWIEGIE 120
LIVQHYTELTTAIRTYQSITERITNSRNKIKQVKENLLSCKMLLHCKRDELRKLWIEGIE
Sbjct: 61 LIVQHYTELTTAIRTYQSITERITNSRNKIKQVKENLLSCKMLLHCKRDELRKLWIEGIE 120
Query: 121 HKHVLNLLDEIENIKQVPQKLEQCMASKHYLSATDMLVSAVESLEGPLLQVEGLSDLRLE 180
HKHVLNLLDEIENIKQVPQKLEQCMASKHYLSATDMLVSAVESLEGPLLQVEGLSDLRLE
Sbjct: 121 HKHVLNLLDEIENIKQVPQKLEQCMASKHYLSATDMLVSAVESLEGPLLQVEGLSDLRLE 180
Query: 181 LHSKKMNLHLVLIDELHRHLYIKSTSRVVQRNKEKGKISSLVKDASVPLIDVTNLPTPRK 240
LHSKKMNLHLVLIDELHRHLYIKSTSRVVQRNKEKGKISSLVKDASVPLIDVTNLPTPRK
Sbjct: 181 LHSKKMNLHLVLIDELHRHLYIKSTSRVVQRNKEKGKISSLVKDASVPLIDVTNLPTPRK 240
Query: 241 FLDTSHYSTAGSSSVREINLQDIKEDLELDPEENSTLFMGILIKGLAKLKKIPETVKAII 300
FLDTSHYSTAGSSSVREINLQDIKEDLELDPEENSTLFMGILIKGLAKLKKIPETVKAII
Sbjct: 241 FLDTSHYSTAGSSSVREINLQDIKEDLELDPEENSTLFMGILIKGLAKLKKIPETVKAII 300
Query: 301 ERLEQELKQIVKRSTTQVADSGYQRGENVTVENQPRLLLELLELLFDKFNAVAAAHSVVL 360
ERLEQELKQIVKRSTTQVADSGYQRGENVTVENQPRLLLELLELLFDKFNAVAAAHSVVL
Sbjct: 301 ERLEQELKQIVKRSTTQVADSGYQRGENVTVENQPRLLLELLELLFDKFNAVAAAHSVVL 360
Query: 361 GYLQDTVVTPLTQQEDIKLYDMADVWVKIQDVLQMLLTEYLDMKNTRTASEPSAQLSYAS 420
GYLQDTVVTPLTQQEDIKLYDMADVWVKIQDVLQMLLTEYLDMKNTRTASEPSAQLSYAS
Sbjct: 361 GYLQDTVVTPLTQQEDIKLYDMADVWVKIQDVLQMLLTEYLDMKNTRTASEPSAQLSYAS 420
Query: 421 TGREFAAFFAKKKPQRPKNSLFKFESSSHAISMSAYLREQRRELYSRSGELQGGPDDNLI 480
TGREFAAFFAKKKPQRPKNSLFKFESSSHAISMSAYLREQRRELYSRSGELQGGPDDNLI
Sbjct: 421 TGREFAAFFAKKKPQRPKNSLFKFESSSHAISMSAYLREQRRELYSRSGELQGGPDDNLI 480
Query: 481 EGGGTKFVCKPGARNITVIFHPLLRFIQEIEHALGLGPAKQCPLREFLTVYIKNIFLNQV 540
EGGGTKFVCKPGARNITVIFHPLLRFIQEIEHALGLGPAKQCPLREFLTVYIKNIFLNQV
Sbjct: 481 EGGGTKFVCKPGARNITVIFHPLLRFIQEIEHALGLGPAKQCPLREFLTVYIKNIFLNQV 540
Query: 541 LAEINKEIEGVTKTSDPLKILANADTMKVLGVQRPLLQSTIIVEKTVQDLLNLMHDLSAY 600
LAEINKEIEGVTKTSDPLKILANADTMKVLGVQRPLLQSTIIVEKTVQDLLNLMHDLSAY
Sbjct: 541 LAEINKEIEGVTKTSDPLKILANADTMKVLGVQRPLLQSTIIVEKTVQDLLNLMHDLSAY 600
Query: 601 SDQFLNMVCVKLQEYKDTCTAAYRGIVQSEEKLVISASWAKDDDISRLLKSLPNWMNMAQ 660
SDQFLNMVCVKLQEYKDTCTAAYRGIVQSEEKLVISASWAKDDDISRLLKSLPNWMNMAQ
Sbjct: 601 SDQFLNMVCVKLQEYKDTCTAAYRGIVQSEEKLVISASWAKDDDISRLLKSLPNWMNMAQ 660
Query: 661 PKQLRPKREEEEDFIRAAFGKESEVLIGNLGDKLIPPQDILRDVSDLKALANMHESLEWL 720
PKQLRPKREEEEDFIRAAFGKESEVLIGNLGDKLIPPQDILRDVSDLKALANMHESLEWL
Sbjct: 661 PKQLRPKREEEEDFIRAAFGKESEVLIGNLGDKLIPPQDILRDVSDLKALANMHESLEWL 720
Query: 721 ASRTKSAFSNLSTSQMLSPAQDSHTNTDLPPVSEQIMQTLSELAKSFQDMADRCLLVLHL 780
ASRTKSAFSNLSTSQMLSPAQDSHTNTDLPPVSEQIMQTLSELAKSFQDMADRCLLVLHL
Sbjct: 721 ASRTKSAFSNLSTSQMLSPAQDSHTNTDLPPVSEQIMQTLSELAKSFQDMADRCLLVLHL 780
Query: 781 EVRVHCFHYLIPLAKEGNYAIVANVESMDYDPLVVKLNKDISAIEEAMSASLQQHKFQYI 840
EVRVHCFHYLIPLAKEGNYAIVANVESMDYDPLVVKLNKDISAIEEAMSASLQQHKFQYI
Sbjct: 781 EVRVHCFHYLIPLAKEGNYAIVANVESMDYDPLVVKLNKDISAIEEAMSASLQQHKFQYI 840
Query: 841 FEGLGHLISCILINGAQYFRRISESGIKKMCRNIFVLQQNLTNITMSREADLDFARQYYE 900
FEGLGHLISCILINGAQYFRRISESGIKKMCRNIFVLQQNLTNITMSREADLDFARQYYE
Sbjct: 841 FEGLGHLISCILINGAQYFRRISESGIKKMCRNIFVLQQNLTNITMSREADLDFARQYYE 900
Query: 901 MLYNTADELLNLVVDQGVKYTELEYIHALTLLHRSQTGVGELTTQNTRLQRLKEIICEQA 960
MLYNTADELLNLVVDQGVKYTELEYIHALTLLHRSQTGVGELTTQNTRLQRLKEIICEQA
Sbjct: 901 MLYNTADELLNLVVDQGVKYTELEYIHALTLLHRSQTGVGELTTQNTRLQRLKEIICEQA 960
Query: 961 AIKQATKDKKITTV 974
AIKQATKDKKITTV
Sbjct: 961 AIKQATKDKKITTV 974
>gi|82546832 SEC8 protein isoform b [Homo sapiens]
Length = 473
Score = 914 bits (2362), Expect = 0.0
Identities = 473/473 (100%), Positives = 473/473 (100%)
Query: 1 MAAEAAGGKYRSTVSKSKDPSGLLISVIRTLSTSDDVEDRENEKGRLEEAYEKCDRDLDE 60
MAAEAAGGKYRSTVSKSKDPSGLLISVIRTLSTSDDVEDRENEKGRLEEAYEKCDRDLDE
Sbjct: 1 MAAEAAGGKYRSTVSKSKDPSGLLISVIRTLSTSDDVEDRENEKGRLEEAYEKCDRDLDE 60
Query: 61 LIVQHYTELTTAIRTYQSITERITNSRNKIKQVKENLLSCKMLLHCKRDELRKLWIEGIE 120
LIVQHYTELTTAIRTYQSITERITNSRNKIKQVKENLLSCKMLLHCKRDELRKLWIEGIE
Sbjct: 61 LIVQHYTELTTAIRTYQSITERITNSRNKIKQVKENLLSCKMLLHCKRDELRKLWIEGIE 120
Query: 121 HKHVLNLLDEIENIKQVPQKLEQCMASKHYLSATDMLVSAVESLEGPLLQVEGLSDLRLE 180
HKHVLNLLDEIENIKQVPQKLEQCMASKHYLSATDMLVSAVESLEGPLLQVEGLSDLRLE
Sbjct: 121 HKHVLNLLDEIENIKQVPQKLEQCMASKHYLSATDMLVSAVESLEGPLLQVEGLSDLRLE 180
Query: 181 LHSKKMNLHLVLIDELHRHLYIKSTSRVVQRNKEKGKISSLVKDASVPLIDVTNLPTPRK 240
LHSKKMNLHLVLIDELHRHLYIKSTSRVVQRNKEKGKISSLVKDASVPLIDVTNLPTPRK
Sbjct: 181 LHSKKMNLHLVLIDELHRHLYIKSTSRVVQRNKEKGKISSLVKDASVPLIDVTNLPTPRK 240
Query: 241 FLDTSHYSTAGSSSVREINLQDIKEDLELDPEENSTLFMGILIKGLAKLKKIPETVKAII 300
FLDTSHYSTAGSSSVREINLQDIKEDLELDPEENSTLFMGILIKGLAKLKKIPETVKAII
Sbjct: 241 FLDTSHYSTAGSSSVREINLQDIKEDLELDPEENSTLFMGILIKGLAKLKKIPETVKAII 300
Query: 301 ERLEQELKQIVKRSTTQVADSGYQRGENVTVENQPRLLLELLELLFDKFNAVAAAHSVVL 360
ERLEQELKQIVKRSTTQVADSGYQRGENVTVENQPRLLLELLELLFDKFNAVAAAHSVVL
Sbjct: 301 ERLEQELKQIVKRSTTQVADSGYQRGENVTVENQPRLLLELLELLFDKFNAVAAAHSVVL 360
Query: 361 GYLQDTVVTPLTQQEDIKLYDMADVWVKIQDVLQMLLTEYLDMKNTRTASEPSAQLSYAS 420
GYLQDTVVTPLTQQEDIKLYDMADVWVKIQDVLQMLLTEYLDMKNTRTASEPSAQLSYAS
Sbjct: 361 GYLQDTVVTPLTQQEDIKLYDMADVWVKIQDVLQMLLTEYLDMKNTRTASEPSAQLSYAS 420
Query: 421 TGREFAAFFAKKKPQRPKNSLFKFESSSHAISMSAYLREQRRELYSRSGELQG 473
TGREFAAFFAKKKPQRPKNSLFKFESSSHAISMSAYLREQRRELYSRSGELQG
Sbjct: 421 TGREFAAFFAKKKPQRPKNSLFKFESSSHAISMSAYLREQRRELYSRSGELQG 473
>gi|215982794 myosin VA isoform 2 [Homo sapiens]
Length = 1828
Score = 48.1 bits (113), Expect = 4e-05
Identities = 69/322 (21%), Positives = 139/322 (43%), Gaps = 33/322 (10%)
Query: 40 RENEKGRLE----EAYEKCDRDLDELIVQHYTELTTAIRTYQSITERITNSRNKIKQVKE 95
RE +K ++E E Y+K ++ I+Q ++ + Y+ + E++TN E
Sbjct: 903 RELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETE 962
Query: 96 NLLSCKMLLHCKRDELRKLWIEGIEHKHVLNLLDEIENIKQVPQKLEQCMASK------- 148
L S L +E + + VL+L +EI ++ + LEQ + K
Sbjct: 963 KLRSDLERLQLSEEEAK------VATGRVLSLQEEIAKLR---KDLEQTRSEKKCIEEHA 1013
Query: 149 -HYLSATDMLVSAVESLEGPLLQVEGLSDLRLELHSKKM--NLHLVLIDELHRHLYIKST 205
Y T+ LVS ++ L Q + + R+ +K+M + L++E + +
Sbjct: 1014 DRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETKQLELDLND 1073
Query: 206 SRVVQRN--KEKGKISSLVKDASVPLIDVTNLPTP-RKFLDTSHYSTAG----SSSVREI 258
R+ +N E ++ D + + ++P P K D++H S SS + E
Sbjct: 1074 ERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAE- 1132
Query: 259 NLQDIKEDLELDPEENSTLFMGILIKGLAKLKKIPETVKAIIERLEQELKQIVKRSTTQV 318
++DI E E+ L M + +K ++ ++ + + + + L+++ +Q++ RS +
Sbjct: 1133 -MEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQVL-RSKAKE 1190
Query: 319 ADSGYQRGENVTVENQPRLLLE 340
+ RG + E+ R LE
Sbjct: 1191 EERPQIRGAELEYESLKRQELE 1212
Score = 30.4 bits (67), Expect = 8.4
Identities = 38/189 (20%), Positives = 79/189 (41%), Gaps = 26/189 (13%)
Query: 36 DVEDRENEKGRLEEAYEKCDRDLDELIVQHYTELTTAIRTYQSITERITNSRNKIKQVKE 95
D+E +EK +EE ++ ++ ++L+ E T + +++ RI ++ + E
Sbjct: 998 DLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETME 1057
Query: 96 NLLSCKMLLHCKRDELRKLWIE-GIEHKHVLNLLDEIENIKQVPQKLEQCMASKHYL--- 151
L +E ++L ++ E NLL+E +++ L++ M ++
Sbjct: 1058 KKLV---------EETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKP 1108
Query: 152 --SATDMLVSAVES---LEGPLLQVEGLSDLRLELHSKKMNLHLVLIDELHRHLYIKSTS 206
TD S+ ES + ++E + E KK+ L + L++K
Sbjct: 1109 GHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDM--------SLFLKLQK 1160
Query: 207 RVVQRNKEK 215
RV + +EK
Sbjct: 1161 RVTELEQEK 1169
>gi|215982791 myosin VA isoform 1 [Homo sapiens]
Length = 1855
Score = 48.1 bits (113), Expect = 4e-05
Identities = 69/322 (21%), Positives = 139/322 (43%), Gaps = 33/322 (10%)
Query: 40 RENEKGRLE----EAYEKCDRDLDELIVQHYTELTTAIRTYQSITERITNSRNKIKQVKE 95
RE +K ++E E Y+K ++ I+Q ++ + Y+ + E++TN E
Sbjct: 903 RELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETE 962
Query: 96 NLLSCKMLLHCKRDELRKLWIEGIEHKHVLNLLDEIENIKQVPQKLEQCMASK------- 148
L S L +E + + VL+L +EI ++ + LEQ + K
Sbjct: 963 KLRSDLERLQLSEEEAK------VATGRVLSLQEEIAKLR---KDLEQTRSEKKCIEEHA 1013
Query: 149 -HYLSATDMLVSAVESLEGPLLQVEGLSDLRLELHSKKM--NLHLVLIDELHRHLYIKST 205
Y T+ LVS ++ L Q + + R+ +K+M + L++E + +
Sbjct: 1014 DRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETKQLELDLND 1073
Query: 206 SRVVQRN--KEKGKISSLVKDASVPLIDVTNLPTP-RKFLDTSHYSTAG----SSSVREI 258
R+ +N E ++ D + + ++P P K D++H S SS + E
Sbjct: 1074 ERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAE- 1132
Query: 259 NLQDIKEDLELDPEENSTLFMGILIKGLAKLKKIPETVKAIIERLEQELKQIVKRSTTQV 318
++DI E E+ L M + +K ++ ++ + + + + L+++ +Q++ RS +
Sbjct: 1133 -MEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQVL-RSKAKE 1190
Query: 319 ADSGYQRGENVTVENQPRLLLE 340
+ RG + E+ R LE
Sbjct: 1191 EERPQIRGAELEYESLKRQELE 1212
Score = 30.4 bits (67), Expect = 8.4
Identities = 38/189 (20%), Positives = 79/189 (41%), Gaps = 26/189 (13%)
Query: 36 DVEDRENEKGRLEEAYEKCDRDLDELIVQHYTELTTAIRTYQSITERITNSRNKIKQVKE 95
D+E +EK +EE ++ ++ ++L+ E T + +++ RI ++ + E
Sbjct: 998 DLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETME 1057
Query: 96 NLLSCKMLLHCKRDELRKLWIE-GIEHKHVLNLLDEIENIKQVPQKLEQCMASKHYL--- 151
L +E ++L ++ E NLL+E +++ L++ M ++
Sbjct: 1058 KKLV---------EETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKP 1108
Query: 152 --SATDMLVSAVES---LEGPLLQVEGLSDLRLELHSKKMNLHLVLIDELHRHLYIKSTS 206
TD S+ ES + ++E + E KK+ L + L++K
Sbjct: 1109 GHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDM--------SLFLKLQK 1160
Query: 207 RVVQRNKEK 215
RV + +EK
Sbjct: 1161 RVTELEQEK 1169
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 44.3 bits (103), Expect = 6e-04
Identities = 75/358 (20%), Positives = 147/358 (41%), Gaps = 30/358 (8%)
Query: 38 EDRENEKGRLEEAYEKCDRDLDELIVQHYTELTTAIRTYQSITERITNSRNKIKQVKENL 97
E+ ENE LE+ E + + L + E A+ S ER K+K+ ++
Sbjct: 628 EELENELHHLEKENELLQKKITNLKIT--CEKIEALEQENSELER---ENRKLKKTLDSF 682
Query: 98 LSCKMLLHCKRDELRKLWIEGIEHKHVLNLLDEIENIKQVPQKLEQC-MASKHYLSATDM 156
+ L E +L E +E L +E++K K+ Q + +K S +
Sbjct: 683 KNLTFQLESLEKENSQLDEENLE------LRRNVESLKCASMKMAQLQLENKELESEKEQ 736
Query: 157 LVSAVESLEGPLLQVEGLSDLRLELHSKKMNLHLVL------IDELHRHLY-IKSTSRVV 209
L +E L+ + E L L + L L I +L L ++ ++ +
Sbjct: 737 LKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTL 796
Query: 210 QRNKEKGKISS-----LVKDASVPLIDVTNLPTPRKFLDTSHYSTAGSSSVREINLQDIK 264
Q+N E+ KISS L K+ + + L +K L+ + + +++ L++
Sbjct: 797 QKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENN 856
Query: 265 EDLELDPEENSTLF--MGILIKGLAKLKKIPETVKAIIERLEQELKQIVKRSTTQVADSG 322
+ +EN TL +GI + +LK++ + K +++R ++K +V V++
Sbjct: 857 VKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKL 916
Query: 323 YQRGENVTVENQPRLL----LELLELLFDKFNAVAAAHSVVLGYLQDTVVTPLTQQED 376
+ N +E L L LL D+ + + + ++ L+ T+ L +E+
Sbjct: 917 KTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEE 974
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 43.9 bits (102), Expect = 7e-04
Identities = 63/289 (21%), Positives = 121/289 (41%), Gaps = 26/289 (8%)
Query: 38 EDRENEKGRLEEAYEKCDRDLDELIVQHYTELTTAIRTYQSITERITNSRNKIKQVKENL 97
E+ ENE LE+ E + + L + E A+ S ER K+K+ ++
Sbjct: 628 EELENELHHLEKENELLQKKITNLKIT--CEKIEALEQENSELER---ENRKLKKTLDSF 682
Query: 98 LSCKMLLHCKRDELRKLWIEGIEHKHVLNLLDEIENIKQVPQKLEQC-MASKHYLSATDM 156
+ L E +L E +E L +E++K K+ Q + +K S +
Sbjct: 683 KNLTFQLESLEKENSQLDEENLE------LRRNVESLKCASMKMAQLQLENKELESEKEQ 736
Query: 157 LVSAVESLEGPLLQVEGLSDLRLELHSKKMNLHLVL------IDELHRHLY-IKSTSRVV 209
L +E L+ + E L L + L L I +L L ++ ++ +
Sbjct: 737 LKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTL 796
Query: 210 QRNKEKGKISS-----LVKDASVPLIDVTNLPTPRKFLDTSHYSTAGSSSVREINLQDIK 264
Q+N E+ KISS L K+ + + L +K L+ + + +++ L++
Sbjct: 797 QKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENN 856
Query: 265 EDLELDPEENSTLF--MGILIKGLAKLKKIPETVKAIIERLEQELKQIV 311
+ +EN TL +GI + +LK++ + K +++R ++K +V
Sbjct: 857 VKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLV 905
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 43.5 bits (101), Expect = 0.001
Identities = 57/292 (19%), Positives = 128/292 (43%), Gaps = 25/292 (8%)
Query: 32 STSDDVEDRENEKGRLEEAYEKCDRDLDELIVQHYT---ELTTAIRTYQSITERITNSRN 88
S + + +D + + L+ ++ ++ E++ +H EL A + E I R
Sbjct: 1439 SVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRV 1498
Query: 89 KIKQVKENLLSCKMLLHCKRDELRKLWIEGIEHKHVLNLLDEIENIKQVPQKLEQCMASK 148
+ + + + + + L D+L+ E E + N I+ I +V +K+ + K
Sbjct: 1499 NLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFN----IKQISEVQEKVNELKQFK 1554
Query: 149 HYLSATDMLVSAVESLEGPLLQV-----EGLSDLRLELHSKKMNLHLVLIDELHRHLYIK 203
+ A D SA++S+E +L++ E ++++ + K+ + ++ R +
Sbjct: 1555 EHRKAKD---SALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQLKE 1611
Query: 204 STSRVVQRNKEKGKISSLVKDASVPLIDVTNLPTPRKFLDTSHYSTAGSSSVREINLQDI 263
+T +V + KE S K+ + N T K + H +++NL++I
Sbjct: 1612 NTKEIVAKMKE-----SQEKEYQFLKMTAVN-ETQEKMCEIEHLKE--QFETQKLNLENI 1663
Query: 264 K-EDLELDPEENSTL-FMGILIKGLAKLKKIPETVKAIIERLEQELKQIVKR 313
+ E++ L + L M + K L+ + ET+K ++L++ L++ + R
Sbjct: 1664 ETENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRETITR 1715
Score = 40.8 bits (94), Expect = 0.006
Identities = 65/331 (19%), Positives = 148/331 (44%), Gaps = 37/331 (11%)
Query: 49 EAYEKCDR--DLDELIVQHYTELTTAIRTYQSITERITNSRNKIKQVKENLLSCKMLLHC 106
E CDR +++E + + +L + ++ E ++ + KI ++ ENL K L
Sbjct: 1114 ELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEI-ENL---KNELKN 1169
Query: 107 KRDELRKLWIEGIEHKHVLNL-LDEIENIKQVPQKLEQCMASKHYLSATDMLVSAVESLE 165
K L + E +E LN +E+++I + + L++ K + + D L + +E
Sbjct: 1170 KELTLEHMETERLELAQKLNENYEEVKSITKERKVLKELQ--KSFETERDHLRGYIREIE 1227
Query: 166 GPLLQVEGLSDLRL-ELHSKKMNLHLVLIDELHRHLYIKSTSRVVQRNKEKGKISSLVKD 224
LQ + +L++ +H K+ H IDEL R + K+ + ++ EK + L ++
Sbjct: 1228 ATGLQTK--EELKIAHIHLKE---HQETIDELRRSVSEKTAQIINTQDLEKSH-TKLQEE 1281
Query: 225 ASVPLIDVTNLPTPRKFLDTSHY-----------STAGSSSVREINLQDIKEDLELDPEE 273
V + LP ++ +T +T S+++ I ++ ++ + + +
Sbjct: 1282 IPVLHEEQELLPNVKEVSETQETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQESQ 1341
Query: 274 NSTLFMGILIKGLAKLKKIPETVKAIIERLEQELKQIVKRSTTQVADSGYQRGENVTV-- 331
IK L K + +T+K +E +LK+ ++ + ++ +S ++ +++ +
Sbjct: 1342 EE-------IKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQSKQEQSLNMKE 1394
Query: 332 -ENQPRLLLELLELLFDKFNAVAAAHSVVLG 361
+N+ ++ +E K +A+ +LG
Sbjct: 1395 KDNETTKIVSEMEQFKPKDSALLRIEIEMLG 1425
Score = 38.5 bits (88), Expect = 0.031
Identities = 122/622 (19%), Positives = 249/622 (40%), Gaps = 105/622 (16%)
Query: 170 QVEGLSDLRLELHSKKMNLHLVLIDELHRHLYIKSTSRVVQRNKEKGKISSLVKDASVPL 229
+++ L+ R L + K L V D+L H I+ T +Q ++ K + S +K+
Sbjct: 1343 EIKSLTKERDNLKTIKEALE-VKHDQLKEH--IRETLAKIQESQSKQEQSLNMKEKDNET 1399
Query: 230 IDVTNLPTPRKFLDTSHYSTAGSSSVR-EINLQDIKEDLELDPEENSTLFMGILIKGLAK 288
+ + + + S+ +R EI + + + L+ +E M + K
Sbjct: 1400 TKIVS--------EMEQFKPKDSALLRIEIEMLGLSKRLQESHDE-----MKSVAKEKDD 1446
Query: 289 LKKIPETVKAIIERLEQELKQIVKRSTTQVADSGYQRGENVTVENQPRLLLELLELLFDK 348
L+++ E +++ ++L++ +K+IV + + + + ++ Q + EL L +K
Sbjct: 1447 LQRLQEVLQSESDQLKENIKEIVAKHLETEEEL---KVAHCCLKEQEETINELRVNLSEK 1503
Query: 349 FNAVAAAHS---VVLGYLQDTVVTPLTQQEDIKLYDMADVWVKIQDVLQMLLTEYLDMKN 405
++ + LQ+ + ++E + +++V K+ ++ Q E+ K+
Sbjct: 1504 ETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEKVNELKQF--KEHRKAKD 1561
Query: 406 TRTASEPSAQLSYAS----TGREFAAFFAKKKPQRPKNSLFKFESSSHAISMSAYLREQR 461
+ S S L + + E +K+ + + E L+E
Sbjct: 1562 SALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQ--------LKENT 1613
Query: 462 RELYSRSGELQGGPDDNLIEGGGTKFVCKPGARNITVIFHPLLRFIQEIEHALGLGPAKQ 521
+E+ ++ E Q L K A N T + EIEH ++
Sbjct: 1614 KEIVAKMKESQEKEYQFL----------KMTAVNETQ------EKMCEIEHLKEQFETQK 1657
Query: 522 CPLREFLTVYIKNIFLNQVLAEINKEIEGVTKTSDPLKILANADTMKVLGVQ-RPLLQST 580
L T +NI L Q+L E +E+ VTK D L+ + +T+KV Q + L+ T
Sbjct: 1658 LNLENIET---ENIRLTQILHENLEEMRSVTKERDDLRSV--EETLKVERDQLKENLRET 1712
Query: 581 IIVEKTVQDLLNLMHDLSAYSDQFLNMVCVKLQEYKDTCTAAYRGIVQSEEKLVISASWA 640
I + Q+ L ++H + L+E+++T RGIV
Sbjct: 1713 ITRDLEKQEELKIVH--------------MHLKEHQETID-KLRGIVSE----------- 1746
Query: 641 KDDDISRLLKSLPNWMNMAQPKQLRPKREEEEDFIRAAFGKESEVLIGNLGDKLIPPQDI 700
K ++IS + K L + + + + L K +EE ++ E + DKL + I
Sbjct: 1747 KTNEISNMQKDLEHSNDALKAQDL--KIQEELRIAHMHLKEQQETI-----DKL---RGI 1796
Query: 701 LRDVSDLKALANMHESLEWLASRTKSAFSNLSTSQMLSPAQDSHTNTDLPPVSEQIMQTL 760
+ + +D L+NM + LE ++ + L ++ H L + + +
Sbjct: 1797 VSEKTD--KLSNMQKDLENSNAKLQEKIQELKANE--------HQLITLKKDVNETQKKV 1846
Query: 761 SELAKSFQDMADRCLLVLHLEV 782
SE+ + + + D+ L + LE+
Sbjct: 1847 SEMEQLKKQIKDQSLTLSKLEI 1868
Score = 30.8 bits (68), Expect = 6.5
Identities = 61/292 (20%), Positives = 121/292 (41%), Gaps = 31/292 (10%)
Query: 35 DDVEDRENEKGRLEEAYEKCDRDLDELIVQHYTELTTAIRTYQSITERITNSRNKIKQVK 94
++ E E L + +K D L L TEL+ + Q T + N+++Q+K
Sbjct: 838 EENERMNQEIVNLSKEAQKFDSSLGAL----KTELSYKTQELQEKTREVQERLNEMEQLK 893
Query: 95 ENLLSCKMLLHCKRDELRKLWIEGIEH--KHVLNLLDEIENIKQVPQKL--EQCMASKHY 150
E L + L E + L E ++ + V L E +++KQ+ + L E+
Sbjct: 894 EQLENRDSTLQTVERE-KTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQLKSDI 952
Query: 151 LSATDMLVSAVESLEGPLLQVEGLSDLRLELHSKKMN-LHLVLIDELHRHLYIKSTSRVV 209
+M + E L L L+ H + +N L + +E+ R+L+++ +
Sbjct: 953 HDTVNMNIDTQEQLRNALES--------LKQHQETINTLKSKISEEVSRNLHMEENTGET 1004
Query: 210 QRNKEKGKISSLVKDASVPLIDVTNLPTPRKFLDTSHYSTAGSSSVREIN-LQDI----- 263
+++ + K+ + K + + L K + S ++E N LQ +
Sbjct: 1005 -KDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQQMLESVI 1063
Query: 264 --KEDLELDPEENSTLFMGILIKGLAKLKKIPETVKAIIERLEQELKQIVKR 313
KE L+ D +EN + + I+ +L+ + + +K E + QE +K+
Sbjct: 1064 AEKEQLKTDLKEN----IEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKK 1111
>gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]
Length = 1979
Score = 41.2 bits (95), Expect = 0.005
Identities = 56/257 (21%), Positives = 110/257 (42%), Gaps = 24/257 (9%)
Query: 37 VEDRENEKGRLEEAYEKCDRDLDELIVQHYTELTTAIRTYQSITERITNSRNKIKQVKEN 96
+ED+ K +L ++ ++ +++DE QH T + + E I + + I+Q+K
Sbjct: 919 IEDQNQSKMQLLQSLQEQKKEMDEFRYQHEQMNATHTQLFLEKDEEIKSLQKTIEQIKTQ 978
Query: 97 LLSCKMLLHCKRDEL------RKLWIEGIEHKHVLNLLDEIENIKQVPQK-LEQCMASKH 149
L + + ++ + L IE KH L+ + +K + ++ LE + ++
Sbjct: 979 LHEERQDIQTDNSDIFQETKVQSLNIENGSEKHDLSKAETERLVKGIKERELEIKLLNEK 1038
Query: 150 YLSATDMLVSAVESLEGPLLQVEGLSDLRLE-LHSK-KMNLHLVLIDELHRHL--YIKST 205
+S T + + G L Q+ DL ++ LH++ H + L + L Y
Sbjct: 1039 NISLTKQIDQLSKDEVGKLTQIIQQKDLEIQALHARISSTSHTQDVVYLQQQLQAYAMER 1098
Query: 206 SRVVQRNKEKGKISSLVKDASVPLIDVT--------NLPTPRKFLDTSHYSTAGSSSVRE 257
+V EK + +S +K ++D+ L K L T + ++G RE
Sbjct: 1099 EKVFAVLNEKTRENSHLKTEYHKMMDIVAAKEAALIKLQDENKKLST-RFESSGQDMFRE 1157
Query: 258 I--NLQDI--KEDLELD 270
NL I ++D+E+D
Sbjct: 1158 TIQNLSRIIREKDIEID 1174
>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
Length = 1684
Score = 40.8 bits (94), Expect = 0.006
Identities = 56/262 (21%), Positives = 112/262 (42%), Gaps = 36/262 (13%)
Query: 41 ENEKGRLEEAYEKCD---RDLDELIVQHYTELTTAIRTYQSITERITNSRNKIKQVKENL 97
+ EK +L++ ++ + +D + + + E+ R + + +++TN NKI+ +++ +
Sbjct: 1132 QKEKKQLQKTMQELELVKKDAQQTTLMNM-EIADYERLMKELNQKLTNKNNKIEDLEQEI 1190
Query: 98 LSCKMLLHCKRDELRKLWIEGIEHKHVLNLLDEIENIKQVPQKLEQCMASKHYLSATDML 157
K ++E+ L V ++ IKQ+ K ++ +A ++
Sbjct: 1191 KIQKQKQETLQEEITSL------QSSVQQYEEKNTKIKQLLVKTKKELADSKQAETDHLI 1244
Query: 158 VSAVESLEGPL----LQVE----GLSDLRLELHSKKMNLHLVLIDELHRHLYIKSTSRVV 209
+ A SL+G L QVE L+++ E H K++ HL E H+ RV
Sbjct: 1245 LQA--SLKGELEASQQQVEVYKIQLAEITSEKH--KIHEHLKTSAEQHQRTLSAYQQRVT 1300
Query: 210 QRNKE----KGKISSLVKDASVPLIDVTNLPTPRKFLDTSHYSTAGSSSVRE-------- 257
+E K + +++ + + V N+ +K S T G+ RE
Sbjct: 1301 ALQEECRAAKAEQATVTSEFESYKVRVHNVLKQQKNKSMSQAETEGAKQEREHLEMLIDQ 1360
Query: 258 --INLQDIKEDLELDPEENSTL 277
I LQD + +L+++ E TL
Sbjct: 1361 LKIKLQDSQNNLQINVSELQTL 1382
>gi|118498356 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 38.9 bits (89), Expect = 0.024
Identities = 97/503 (19%), Positives = 201/503 (39%), Gaps = 93/503 (18%)
Query: 14 VSKSKDPSGLLISVIRTLSTSDDVEDR-----ENEKGRL--EEAYEKCDRDLDEL----- 61
V+K + L + TL + +E R E+E+ R+ EE+ + +D+ E
Sbjct: 523 VAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALK 582
Query: 62 --IVQHYTEL---TTAIRTYQSITERITNSRNKIKQVKENLLSCKMLLHCKRDELRKLWI 116
I Q ++++ T+A + + + I +IKQ +++L S + L K +EL+ +
Sbjct: 583 AQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQN 642
Query: 117 EGIEHKHVLNLLDEIENIK-QVPQKLEQCMASKHYLSATDMLV--SAVESLEGPLLQVEG 173
K + L + N + +LE+ S + L+ + + + +
Sbjct: 643 MNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKI 702
Query: 174 LSDLRLELHSKKMNLHLVLIDELHRHLYIKSTSRVVQRNKEKGKISSLVKDASVPLIDVT 233
L+D L S+ L ++ ++ ++ + ++ + +Q EK
Sbjct: 703 LNDQNKALKSEVQKLQTLVSEQPNKDV-VEQMEKCIQEKDEK------------------ 743
Query: 234 NLPTPRKFLDTSHYSTAGS----SSVREINLQDIKEDLELDPEENSTLFMGILIKGL--- 286
L T + L+T A +++R N KE +L ++N + L++ L
Sbjct: 744 -LKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKV 802
Query: 287 -----AKLKKIPETVKAII------ERLEQELKQIVKRSTTQVADSGYQRGENVTVENQP 335
K+K + E ++A + E+ Q+LKQ +K ++ + ++ + +++ ++
Sbjct: 803 IHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKV 862
Query: 336 RLLLELLELLFDKFNAVAAAHSVVLGYLQDTVVTPLTQQEDIKLYDMADVWVKIQDVLQM 395
+ L LL+ ++ N + A L ++E D+A+ +QD+ +
Sbjct: 863 QELQNLLKGKEEQMNTMKAV---------------LEEKEK----DLANTGKWLQDLQEE 903
Query: 396 LLTEYLDMKNTRTASEPSAQLSYASTGREFAAFFAKKKPQRPKNSLFKFESSSHAISMSA 455
E L A + S AS E +K +N L + E A
Sbjct: 904 --NESLKAHVQEVAQHNLKEASSASQFEELEIVLKEK-----ENELKRLE---------A 947
Query: 456 YLREQRRELYSRSGELQGGPDDN 478
L+E+ +L S++ LQ D+N
Sbjct: 948 MLKERESDLSSKTQLLQDVQDEN 970
>gi|118498368 kinectin 1 isoform c [Homo sapiens]
Length = 1300
Score = 38.9 bits (89), Expect = 0.024
Identities = 97/503 (19%), Positives = 201/503 (39%), Gaps = 93/503 (18%)
Query: 14 VSKSKDPSGLLISVIRTLSTSDDVEDR-----ENEKGRL--EEAYEKCDRDLDEL----- 61
V+K + L + TL + +E R E+E+ R+ EE+ + +D+ E
Sbjct: 523 VAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALK 582
Query: 62 --IVQHYTEL---TTAIRTYQSITERITNSRNKIKQVKENLLSCKMLLHCKRDELRKLWI 116
I Q ++++ T+A + + + I +IKQ +++L S + L K +EL+ +
Sbjct: 583 AQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQN 642
Query: 117 EGIEHKHVLNLLDEIENIK-QVPQKLEQCMASKHYLSATDMLV--SAVESLEGPLLQVEG 173
K + L + N + +LE+ S + L+ + + + +
Sbjct: 643 MNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKI 702
Query: 174 LSDLRLELHSKKMNLHLVLIDELHRHLYIKSTSRVVQRNKEKGKISSLVKDASVPLIDVT 233
L+D L S+ L ++ ++ ++ + ++ + +Q EK
Sbjct: 703 LNDQNKALKSEVQKLQTLVSEQPNKDV-VEQMEKCIQEKDEK------------------ 743
Query: 234 NLPTPRKFLDTSHYSTAGS----SSVREINLQDIKEDLELDPEENSTLFMGILIKGL--- 286
L T + L+T A +++R N KE +L ++N + L++ L
Sbjct: 744 -LKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKV 802
Query: 287 -----AKLKKIPETVKAII------ERLEQELKQIVKRSTTQVADSGYQRGENVTVENQP 335
K+K + E ++A + E+ Q+LKQ +K ++ + ++ + +++ ++
Sbjct: 803 IHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKV 862
Query: 336 RLLLELLELLFDKFNAVAAAHSVVLGYLQDTVVTPLTQQEDIKLYDMADVWVKIQDVLQM 395
+ L LL+ ++ N + A L ++E D+A+ +QD+ +
Sbjct: 863 QELQNLLKGKEEQMNTMKAV---------------LEEKEK----DLANTGKWLQDLQEE 903
Query: 396 LLTEYLDMKNTRTASEPSAQLSYASTGREFAAFFAKKKPQRPKNSLFKFESSSHAISMSA 455
E L A + S AS E +K +N L + E A
Sbjct: 904 --NESLKAHVQEVAQHNLKEASSASQFEELEIVLKEK-----ENELKRLE---------A 947
Query: 456 YLREQRRELYSRSGELQGGPDDN 478
L+E+ +L S++ LQ D+N
Sbjct: 948 MLKERESDLSSKTQLLQDVQDEN 970
>gi|33620775 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 38.9 bits (89), Expect = 0.024
Identities = 97/503 (19%), Positives = 201/503 (39%), Gaps = 93/503 (18%)
Query: 14 VSKSKDPSGLLISVIRTLSTSDDVEDR-----ENEKGRL--EEAYEKCDRDLDEL----- 61
V+K + L + TL + +E R E+E+ R+ EE+ + +D+ E
Sbjct: 523 VAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALK 582
Query: 62 --IVQHYTEL---TTAIRTYQSITERITNSRNKIKQVKENLLSCKMLLHCKRDELRKLWI 116
I Q ++++ T+A + + + I +IKQ +++L S + L K +EL+ +
Sbjct: 583 AQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQN 642
Query: 117 EGIEHKHVLNLLDEIENIK-QVPQKLEQCMASKHYLSATDMLV--SAVESLEGPLLQVEG 173
K + L + N + +LE+ S + L+ + + + +
Sbjct: 643 MNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKI 702
Query: 174 LSDLRLELHSKKMNLHLVLIDELHRHLYIKSTSRVVQRNKEKGKISSLVKDASVPLIDVT 233
L+D L S+ L ++ ++ ++ + ++ + +Q EK
Sbjct: 703 LNDQNKALKSEVQKLQTLVSEQPNKDV-VEQMEKCIQEKDEK------------------ 743
Query: 234 NLPTPRKFLDTSHYSTAGS----SSVREINLQDIKEDLELDPEENSTLFMGILIKGL--- 286
L T + L+T A +++R N KE +L ++N + L++ L
Sbjct: 744 -LKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKV 802
Query: 287 -----AKLKKIPETVKAII------ERLEQELKQIVKRSTTQVADSGYQRGENVTVENQP 335
K+K + E ++A + E+ Q+LKQ +K ++ + ++ + +++ ++
Sbjct: 803 IHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKV 862
Query: 336 RLLLELLELLFDKFNAVAAAHSVVLGYLQDTVVTPLTQQEDIKLYDMADVWVKIQDVLQM 395
+ L LL+ ++ N + A L ++E D+A+ +QD+ +
Sbjct: 863 QELQNLLKGKEEQMNTMKAV---------------LEEKEK----DLANTGKWLQDLQEE 903
Query: 396 LLTEYLDMKNTRTASEPSAQLSYASTGREFAAFFAKKKPQRPKNSLFKFESSSHAISMSA 455
E L A + S AS E +K +N L + E A
Sbjct: 904 --NESLKAHVQEVAQHNLKEASSASQFEELEIVLKEK-----ENELKRLE---------A 947
Query: 456 YLREQRRELYSRSGELQGGPDDN 478
L+E+ +L S++ LQ D+N
Sbjct: 948 MLKERESDLSSKTQLLQDVQDEN 970
>gi|149363642 coiled-coil domain containing 144A [Homo sapiens]
Length = 1427
Score = 38.9 bits (89), Expect = 0.024
Identities = 65/307 (21%), Positives = 135/307 (43%), Gaps = 36/307 (11%)
Query: 79 ITERITNSRNKIKQVKENLLSCKMLLHCKRDELRKLWIEGIEHKHVLNLLDEIENIKQVP 138
++E+++N+ +KI S ++ LH RD L + E + + V L + + K+
Sbjct: 968 LSEKLSNAESKIN-------SLQIQLHNTRDALGR---ESLILERVQRDLSQTQCQKKET 1017
Query: 139 QKLEQCMASK--HYLSATDMLVSAVESLEGP-LLQVEGLSDLRLELHSKKMNLHLVLIDE 195
+++ Q SK Y++ + + + L+ +L + L D + +S++ + D+
Sbjct: 1018 EQMYQIEQSKLKKYIAKQESVEERLSQLQSENMLLRQQLDDAHKKANSQEKTSSTIQ-DQ 1076
Query: 196 LHRHLYIKSTSRVVQRNKEKGKISSLVKDASVPLIDVTNLPTPRKFLDTSHYSTAGSSSV 255
H S ++ +Q EK +S +++ + L+D N R +D AG
Sbjct: 1077 FH------SAAKNLQAESEKQILS--LQEKNKELMDEYNHLKER--MDQCEKEKAG---- 1122
Query: 256 REINLQDIKED-----LELDPEENSTLFMGILIKGLAKLKKIPETVKAIIERLEQELKQI 310
R+I+L + +E L LD E N L + + + ++K ET++ ++L+QE+ +
Sbjct: 1123 RKIDLTEAQETVPSRCLHLDAE-NEVLQLQQTLFSMKAIQKQCETLQKNKKQLKQEVVNL 1181
Query: 311 VKRSTTQVADSGYQRGENVTVENQPRLLLE--LLELLFDKFNAVAAAHSVVLGYLQDTVV 368
+ + G + +E + R +E L E + A +H ++ +D
Sbjct: 1182 KSYMERNMLERGKAEWHKLLIEERARKEIEEKLNEAILTLQKQAAVSHEQLVQLREDNTT 1241
Query: 369 TPLTQQE 375
+ TQ E
Sbjct: 1242 SIKTQME 1248
>gi|32189362 PTPRF interacting protein alpha 3 [Homo sapiens]
Length = 1194
Score = 37.7 bits (86), Expect = 0.053
Identities = 34/149 (22%), Positives = 68/149 (45%), Gaps = 8/149 (5%)
Query: 4 EAAGGKYRSTVSKSKDPSGLLISVIRTLSTSDDVEDRENEKGRLEEAYEKCDRDLDELIV 63
E A + R+ V + ++ +L + L +++ E G+ EEA K RDL E +
Sbjct: 239 EEALERQRAEVCQLRERLAVLCRQMSQLE--EELGTAHRELGKAEEANSKLQRDLKEALA 296
Query: 64 QH---YTELTTAIRTYQSITERITNSRNKIKQVKENLLSCKMLLHCKRDELRKL--WIEG 118
Q +TT + Y S T+ + +++ L S + L ++ R+L W++
Sbjct: 297 QREDMEERITTLEKRYLSAQREATSLHDANDKLENELASKESLYRQSEEKSRQLAEWLDD 356
Query: 119 IEHKHVLNLLDEIENIKQVPQKLEQCMAS 147
+ K + L + E + ++ +L Q +A+
Sbjct: 357 AKQK-LQQTLQKAETLPEIEAQLAQRVAA 384
>gi|4758650 kinesin family member 5C [Homo sapiens]
Length = 957
Score = 37.4 bits (85), Expect = 0.069
Identities = 55/256 (21%), Positives = 105/256 (41%), Gaps = 24/256 (9%)
Query: 68 ELTTAIRTYQSITERITNSRNKIKQVKENLLSCKMLLHCKRDELRKLWIEGIEHK-HVLN 126
E T A + + + N+ KQ++ + ++ EL + +H+ + +
Sbjct: 583 EFTMARLYISKMKSEVKSLVNRSKQLESAQMDSNRKMNASERELAACQLLISQHEAKIKS 642
Query: 127 LLDEIENIKQVPQKLEQCMASKHYLSATDMLVSAVESLEGPLLQVEGLSDLRLELHSKKM 186
L D ++N++Q ++LE+ S+ LS + A E + Q + L +++M
Sbjct: 643 LTDYMQNMEQKRRQLEE---SQDSLSEELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEM 699
Query: 187 NLHLVLIDELHRHLYIKSTSRVVQRNKEKGKISSLVKDASVPL-IDVTNLPTPRKFLDTS 245
L E HR + K SR+ +EK KI ++D + L ++ L
Sbjct: 700 KKALEQQMESHREAHQKQLSRLRDEIEEKQKIIDEIRDLNQKLQLEQEKL---------- 749
Query: 246 HYSTAGSSSVREINLQDIKEDLELDPEENSTLFMGILIKGLAKLKKIPETVKAIIERLEQ 305
SS ++ ++D + +++L E L + LK + ETV ++ L
Sbjct: 750 ------SSDYNKLKIEDQEREMKL---EKLLLLNDKREQAREDLKGLEETVSRELQTLHN 800
Query: 306 ELKQIVKRSTTQVADS 321
K V+ TT+V S
Sbjct: 801 LRKLFVQDLTTRVKKS 816
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 37.0 bits (84), Expect = 0.090
Identities = 67/311 (21%), Positives = 126/311 (40%), Gaps = 44/311 (14%)
Query: 25 ISVIRTLST--SDDVEDRENEKGRLEEAYEKCDRDLDELIVQHYTELTTAIRTYQSITER 82
+ V+R L ++ ED E+EK +A EK RDL E + TEL + T + E
Sbjct: 1110 LKVVRELQAQIAELQEDFESEKASRNKA-EKQKRDLSEELEALKTELEDTLDTTAAQQEL 1168
Query: 83 ITNSRNKIKQVKENLLSCKMLLHCKRDELRKLWIEGIEHKHVLNLLDEIENIKQVPQKLE 142
T ++ ++K+ L K E + I+ + +H L + E ++Q +
Sbjct: 1169 RTKREQEVAELKKALEE-----ETKNHEAQ---IQDMRQRHATALEELSEQLEQAKRFKA 1220
Query: 143 QCMASKHYLSATDMLVSAVESLEGPLLQVEGLSDLRLELHSKKMNLHLVLIDELHR---- 198
+K L + ++ +V+ L ++ E K+ L + ELH
Sbjct: 1221 NLEKNKQGLETDNKELAC---------EVKVLQQVKAESEHKRKKLD-AQVQELHAKVSE 1270
Query: 199 --HLYIKSTSRVVQRNKEKGKISSLVKDASVPLI----DVTNL-----PTPRKFLDTSHY 247
L ++ + + E +S+L+++A I D +L T + +
Sbjct: 1271 GDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQ 1330
Query: 248 STAGSSSVREINLQDIKEDLELDPEENSTLFMGILIKGLAKLKKIPETVKAI------IE 301
SS +R+ L++ K L+ EE + + LA ++ +T K + IE
Sbjct: 1331 KLNLSSRIRQ--LEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIE 1388
Query: 302 RLEQELKQIVK 312
LE+ K+++K
Sbjct: 1389 SLEEAKKKLLK 1399
>gi|112420968 coiled-coil domain containing 158 [Homo sapiens]
Length = 1113
Score = 37.0 bits (84), Expect = 0.090
Identities = 79/439 (17%), Positives = 180/439 (41%), Gaps = 44/439 (10%)
Query: 37 VEDRENEKGRLEEAYEKCDRDLDELIVQHYTELTTAIRTYQSITERITNSRNKIKQVKEN 96
V +E + YE +L++ +V +ELT A ++ N ++++++ +
Sbjct: 326 VSQLRSELREAKRMYEDKTEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLAD 385
Query: 97 LLSCKMLLHCKRDELRKLWIEGIEHKHVL-NLLDEIENIKQVPQKLEQCMASKHYLSATD 155
L + L ++++ ++LW + + +L E++N Q+LE + +
Sbjct: 386 LHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDNRNMEVQRLEALLKALK-SECQG 444
Query: 156 MLVSAVESLEGPLLQVEGLSDLRLELHSKKMNLHLVLIDELHRHLYIKSTSRVVQRNKEK 215
+ + +++G +E +S L +L S K L V+ + + + ++S+ R
Sbjct: 445 QMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERT------- 497
Query: 216 GKISSLVKDASVPLIDVTNLPTPRKFLDTSHYSTAGSSSVREINLQDIKE-DLELDPEEN 274
IS L T+L + ++ ++ S ++ LQ+++ E D N
Sbjct: 498 --ISDL----------TTSLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRN 545
Query: 275 STLFMGILIKGLAKLKKIPETVK-AIIERLEQELKQIVKRSTTQVADSGYQRGENVTVE- 332
++ + K+ T K +IE L Q+++ + + +G + E +E
Sbjct: 546 --------VQTECEALKLQMTEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEK 597
Query: 333 --NQPRLLLELLELLFDKFNAVAAAHSVVLGYLQDTVVTPLTQQEDIKLYDMADVWVKIQ 390
N R+ L+ L++L DK +A + L+ V L +L + D+ +
Sbjct: 598 EINDRRMELKELKILKDKKDAKIRELEARVSDLELEKV-KLVNAGSERLRAVKDIKQERD 656
Query: 391 DVLQMLLTEYLDMKN--------TRTASEPSAQLSYASTGREFAAFFAKKKPQRPKNSLF 442
+L + T ++ N R S ++ + + A+ + ++ +N+L
Sbjct: 657 QLLNEVKTSRSELNNLSEEYEVLKRNFRNKSEEMEMTTNKLKMQLKSAQSELEQTRNTLK 716
Query: 443 KFE-SSSHAISMSAYLREQ 460
E S HA+ ++ +++Q
Sbjct: 717 SMEGSDGHAMKVAMGMQKQ 735
>gi|151301127 dynein, axonemal, heavy chain 7 [Homo sapiens]
Length = 4024
Score = 36.6 bits (83), Expect = 0.12
Identities = 37/175 (21%), Positives = 82/175 (46%), Gaps = 11/175 (6%)
Query: 28 IRTLSTSDDVEDRENEKGRLEEAYEKCDRDLDELIVQHYTELTTAIRTYQSITERITNSR 87
+ + +S D+ + E+GR A +K RD+ ++Q LT + T + ER+ S
Sbjct: 990 LEPIFSSPDIMSQMPEEGRRFTAVDKTWRDIMRSVMQDKHVLT--VVTIDRMLERLKKSN 1047
Query: 88 NKIKQVKENLLSCKMLLHCKRDELRKLWIEGIEHKHVLNLLDEIENIKQVPQKLEQCMAS 147
++ + + L L KR + + + + +L +L E ++ +V L++C
Sbjct: 1048 ELLELILKGL---NEYLEKKRLFFPRFFF--LSNDELLEILSETKDPTRVQPHLKKCFEG 1102
Query: 148 KHYLSATDML-VSAVESLEG---PLLQVEGLSDLRLELHSKKMNLHLVLIDELHR 198
+ T+ L ++ ++S EG L+++ + R ++ + L V+I+ +H+
Sbjct: 1103 IAKVEFTETLDITHMKSSEGEVVELIEIISTAKARGQVEKWLVELERVMINSIHK 1157
>gi|34878904 synaptonemal complex protein 1 [Homo sapiens]
Length = 976
Score = 36.6 bits (83), Expect = 0.12
Identities = 65/323 (20%), Positives = 135/323 (41%), Gaps = 33/323 (10%)
Query: 17 SKDPSGLLISVIRTLSTSDDVEDRENEKGRLEEAYEKCDRDLDELIVQHYTELTTAIRTY 76
+K+ + +S+ R++ST LEE + + + +L + T++ + +
Sbjct: 321 TKELEDIKVSLQRSVSTQK----------ALEEDLQIATKTICQLTEEKETQMEESNKAR 370
Query: 77 QSITERITNSRNKIKQVKENLLSCKMLLHCKRDELRKLWIEGIEHKHVLNLLDEIENIKQ 136
+ + +T + ++E L + + L D+L+ L +E + L + ++ N K+
Sbjct: 371 AAHSFVVTEFETTVCSLEELLRTEQQRLEKNEDQLKILTMELQKKSSELEEMTKLTNNKE 430
Query: 137 VP-QKLEQCMASKHYLSATDMLVSAV-ESLEGPLLQVEGLSDLR-LELHSKKMNLHLVLI 193
V ++L++ + K L + + E L+G ++ GL R E+H ++ L +
Sbjct: 431 VELEELKKVLGEKETLLYENKQFEKIAEELKGTEQELIGLLQAREKEVHDLEIQLTAITT 490
Query: 194 DELHRHLYIKSTSRVVQRNKEKG--------KISSLVKDASVPLIDVTNLPTPRKFLDTS 245
E + +K ++ K K K+S K+ + D+T L + D +
Sbjct: 491 SEQYYSKEVKDLKTELENEKLKNTELTSHCNKLSLENKELTQETSDMT-LELKNQQEDIN 549
Query: 246 HYSTAGSSSVREI-NLQD----IKEDLELDPEENSTLFMGILIK------GLAKLKKIPE 294
+ +++I NLQ+ ++ +LE EE + K L+K E
Sbjct: 550 NNKKQEERMLKQIENLQETETQLRNELEYVREELKQKRDEVKCKLDKSEENCNNLRKQVE 609
Query: 295 TVKAIIERLEQELKQIVKRSTTQ 317
IE L+QE K + K+ T +
Sbjct: 610 NKNKYIEELQQENKALKKKGTAE 632
Score = 30.4 bits (67), Expect = 8.4
Identities = 92/481 (19%), Positives = 183/481 (38%), Gaps = 70/481 (14%)
Query: 39 DRENEKGRLEEAYEKCDRDLDELI---VQHYTELTTAIRTYQSITERITNSRNKIKQVKE 95
D EN +G L Y K ++ +++ V EL Q + I R I++++
Sbjct: 95 DLENSEG-LSRVYSKLYKEAEKIKKWKVSTEAELRQKESKLQENRKIIEAQRKAIQELQF 153
Query: 96 NLLSCKMLLHCKRDELRKLWIEGIEHKHVLNLLDEI-----ENIKQVPQKLEQCMASKHY 150
+ L E + L E +H+ NLL E E K+ + E+ + Y
Sbjct: 154 GNEKVSLKLEEGIQENKDLIKENNATRHLCNLLKETCARSAEKTKKYEYEREE--TRQVY 211
Query: 151 LSATDMLVSAVESLEGPLLQVEGLSDLRLELHSKKMNLHLVLIDELHRHLYIKSTSRVVQ 210
+ + + + + E +LR++ + ++ +H L ++ + +++
Sbjct: 212 MDLNNNIEKMITAFE----------ELRVQAENSRLEMHFKLKEDYEKIQHLE------- 254
Query: 211 RNKEKGKISSLVKDASVPLIDVTNLPTPRKFLDTSHYSTAGSSSVREINLQDIKEDLELD 270
+ K +I+ K S+ LI +T K L + S ++N + K L+ +
Sbjct: 255 -QEYKKEINDKEKQVSLLLIQITEKENKMKDL-----TFLLEESRDKVNQLEEKTKLQSE 308
Query: 271 PEENSTLFMGILIKGL----AKLKKIPETVKAIIERLEQELK---QIVKRSTTQVADSGY 323
+ S L K L L++ T KA+ E L+ K Q+ + TQ+ +S
Sbjct: 309 NLKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQIATKTICQLTEEKETQMEESNK 368
Query: 324 QRGEN-----------VTVENQPRLLLELLELLFDKFNAVAAAHSVVLGYLQDTVVTPLT 372
R + ++E R + LE D+ + L++ +T LT
Sbjct: 369 ARAAHSFVVTEFETTVCSLEELLRTEQQRLEKNEDQLKILTMELQKKSSELEE--MTKLT 426
Query: 373 QQEDIKLYDMADV-------------WVKIQDVLQMLLTEYLDMKNTR--TASEPSAQLS 417
++++L ++ V + KI + L+ E + + R + QL+
Sbjct: 427 NNKEVELEELKKVLGEKETLLYENKQFEKIAEELKGTEQELIGLLQAREKEVHDLEIQLT 486
Query: 418 YASTGREFAAFFAKK-KPQRPKNSLFKFESSSHAISMSAYLREQRRELYSRSGELQGGPD 476
+T ++ + K K + L E +SH +S +E +E + EL+ +
Sbjct: 487 AITTSEQYYSKEVKDLKTELENEKLKNTELTSHCNKLSLENKELTQETSDMTLELKNQQE 546
Query: 477 D 477
D
Sbjct: 547 D 547
>gi|224458301 family with sequence similarity 186, member A [Homo
sapiens]
Length = 2351
Score = 36.2 bits (82), Expect = 0.15
Identities = 46/216 (21%), Positives = 89/216 (41%), Gaps = 19/216 (8%)
Query: 215 KGKISSLVKDASVPLIDVTNLPTPRKFLDTSHYSTAGSSSVREINLQDIKEDLELDPEEN 274
KG+I SLV+ S+ D T P K H+ ++G+ + +E ++ KE+L + +
Sbjct: 579 KGEIRSLVEPLSMIQFDDTAEPQKGKIKGKKHHISSGTITSKEEKTEE-KEELTKQVKSH 637
Query: 275 STLFMGILIKGLAKLKKIPETVKAIIERLE--------QELKQIVKRSTTQVADSGYQRG 326
L+K L+++ K ++E + +E ++ + Q D+ +
Sbjct: 638 Q------LVKSLSRVAKETSESTRVLESPDGKSEQSNLEEFQEAIMAFLKQKIDNIGKAF 691
Query: 327 ENVTVENQPRLLLELLELLFDKFNAVAAAHSVVLGYLQDTVVTPLTQQEDIKLYD-MADV 385
+ TV + LL +K + A + +TV L + +D K + + +
Sbjct: 692 DKKTVPKEEELLKRAEA---EKLGIIKAKMEEYFQKVAETVTKILRKYKDTKKEEQVGEK 748
Query: 386 WVKIQDVLQMLLTEYLDMKNTRTASEPSAQLSYAST 421
+K + V+ + + SE S LSY ST
Sbjct: 749 PIKQKKVVSFMPGLHFQKSPISAKSESSTLLSYEST 784
>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
Length = 3907
Score = 35.8 bits (81), Expect = 0.20
Identities = 70/384 (18%), Positives = 157/384 (40%), Gaps = 39/384 (10%)
Query: 37 VEDRENEKGRLEEAYEKCDRDLDELIVQHYTELTTAIRTYQSITERITNSRNKIKQVKEN 96
+E E+E + E+ +R+L+E+ V + TE ++ Q I I Q+ N
Sbjct: 157 LEMMESELAGKQHEIEELNRELEEMRVTYGTE---GLQQLQEFEAAIKQRDGIITQLTAN 213
Query: 97 LLSCKMLLHCKRDELRKLWIEGIEHKHVLNLLDEIENIKQVPQKLEQCMASKHYLSATDM 156
L + ++DE + ++E E L + +Q+ Q E S H +A D+
Sbjct: 214 LQQARR----EKDETMREFLELTEQSQKLQI-----QFQQL-QASETLRNSTHSSTAADL 263
Query: 157 LVSAVESLEGPLLQVEGLSDLRLELHSKK--MNLHLVLIDELHRHLYIKSTSRVVQRNKE 214
L A + + Q+E L + KK + + + E + ++ +V NKE
Sbjct: 264 L-QAKQQILTHQQQLEEQDHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQDKKVENSNKE 322
Query: 215 KGKISSLVKDASVPLIDVTNLPTPRKFLDTSHYSTAGSSSVREINLQDIKEDLEL----- 269
+ + K+ + ++ + +K L+ T + E+ Q ++++ E+
Sbjct: 323 EIQ----EKETIIEELNTKIIEEEKKTLELKDKLTTADKLLGELQEQIVQKNQEIKNMKL 378
Query: 270 ----------DPEENSTLFMGILIKGLAKLKKIPETVKAIIERLEQELKQIVKRSTTQVA 319
E MG + + + K + I++R+EQE ++ +++ ++
Sbjct: 379 ELTNSKQKERQSSEEIKQLMGTVEELQKRNHKDSQFETDIVQRMEQETQRKLEQLRAELD 438
Query: 320 DSGYQRGENVTVENQPRLLLELLELLF----DKFNAVAAAHSVVLGYLQDTVVTPLTQQE 375
+ Q+ + E + + ++ E+ + NA+ + ++ + Q ++ +
Sbjct: 439 EMYGQQIVQMKQELIRQHMAQMEEMKTRHKGEMENALRSYSNITVNEDQIKLMNVAINEL 498
Query: 376 DIKLYDMADVWVKIQDVLQMLLTE 399
+IKL D K+++ L ++L E
Sbjct: 499 NIKLQDTNSQKEKLKEELGLILEE 522
>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
Length = 3899
Score = 35.8 bits (81), Expect = 0.20
Identities = 70/384 (18%), Positives = 157/384 (40%), Gaps = 39/384 (10%)
Query: 37 VEDRENEKGRLEEAYEKCDRDLDELIVQHYTELTTAIRTYQSITERITNSRNKIKQVKEN 96
+E E+E + E+ +R+L+E+ V + TE ++ Q I I Q+ N
Sbjct: 157 LEMMESELAGKQHEIEELNRELEEMRVTYGTE---GLQQLQEFEAAIKQRDGIITQLTAN 213
Query: 97 LLSCKMLLHCKRDELRKLWIEGIEHKHVLNLLDEIENIKQVPQKLEQCMASKHYLSATDM 156
L + ++DE + ++E E L + +Q+ Q E S H +A D+
Sbjct: 214 LQQARR----EKDETMREFLELTEQSQKLQI-----QFQQL-QASETLRNSTHSSTAADL 263
Query: 157 LVSAVESLEGPLLQVEGLSDLRLELHSKK--MNLHLVLIDELHRHLYIKSTSRVVQRNKE 214
L A + + Q+E L + KK + + + E + ++ +V NKE
Sbjct: 264 L-QAKQQILTHQQQLEEQDHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQDKKVENSNKE 322
Query: 215 KGKISSLVKDASVPLIDVTNLPTPRKFLDTSHYSTAGSSSVREINLQDIKEDLEL----- 269
+ + K+ + ++ + +K L+ T + E+ Q ++++ E+
Sbjct: 323 EIQ----EKETIIEELNTKIIEEEKKTLELKDKLTTADKLLGELQEQIVQKNQEIKNMKL 378
Query: 270 ----------DPEENSTLFMGILIKGLAKLKKIPETVKAIIERLEQELKQIVKRSTTQVA 319
E MG + + + K + I++R+EQE ++ +++ ++
Sbjct: 379 ELTNSKQKERQSSEEIKQLMGTVEELQKRNHKDSQFETDIVQRMEQETQRKLEQLRAELD 438
Query: 320 DSGYQRGENVTVENQPRLLLELLELLF----DKFNAVAAAHSVVLGYLQDTVVTPLTQQE 375
+ Q+ + E + + ++ E+ + NA+ + ++ + Q ++ +
Sbjct: 439 EMYGQQIVQMKQELIRQHMAQMEEMKTRHKGEMENALRSYSNITVNEDQIKLMNVAINEL 498
Query: 376 DIKLYDMADVWVKIQDVLQMLLTE 399
+IKL D K+++ L ++L E
Sbjct: 499 NIKLQDTNSQKEKLKEELGLILEE 522
>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
Length = 1946
Score = 35.8 bits (81), Expect = 0.20
Identities = 84/399 (21%), Positives = 167/399 (41%), Gaps = 39/399 (9%)
Query: 41 ENEKG---RLEEAYEKCDRDLDELIVQHYTELTTAI---RTYQSITERITNSRNKIKQVK 94
ENEKG +L++ ++ + +L + E TT R +T+ + + ++++V
Sbjct: 1107 ENEKGLVAQLQKTVKELQTQIKDLKEKLEAERTTRAKMERERADLTQDLADLNERLEEVG 1166
Query: 95 ENLLSCKMLLHCKRDELRKLWIE-------------GIEHKHVLNLLD---EIENIKQVP 138
+ L+ + + + +KL + ++ +H +L + ++EN++QV
Sbjct: 1167 GSSLAQLEITKKQETKFQKLHRDMEEATLHFETTSASLKKRHADSLAELEGQVENLQQVK 1226
Query: 139 QKLEQCMASKHYLSATDMLVSAVESLEGPLLQVEGLSDL---RLELHSKKMNLHLVLIDE 195
QKLE+ + D L++ VE + E L L RL + K++ L ++
Sbjct: 1227 QKLEKDKSDLQL--EVDDLLTRVEQMTRAKANAEKLCTLYEERLHEATAKLDKVTQLAND 1284
Query: 196 L---HRHLYIKSTSRVVQRNKEKGKISSLVKDASVPLIDVTNL--PTPRKFLDTSHYSTA 250
L L+ +S + + +++ I+ L ++ S + +L ++ S + A
Sbjct: 1285 LAAQKTKLWSESGEFLRRLEEKEALINQLSREKSNFTRQIEDLRGQLEKETKSQSALAHA 1344
Query: 251 GSSSVREINL--QDIKEDLELDPEENSTLFMGILIKGLAKLKKIPETVKAIIERLEQELK 308
+ R+ +L + +E+ E+ E + TL + + + K V E LE K
Sbjct: 1345 LQKAQRDCDLLREQYEEEQEVKAELHRTL-SKVNAEMVQWRMKYENNVIQRTEDLEDAKK 1403
Query: 309 QIVKRSTTQVADSGYQRGENVTVEN-QPRLLLELLELLFDKFNAVAAAHSVVLGYLQDTV 367
++ R G N ++E + +L LEL + L D +AA + LQ
Sbjct: 1404 ELAIRLQEAAEAMGVANARNASLERARHQLQLELGDALSDLGKVRSAAARLDQKQLQSGK 1463
Query: 368 VTPLTQQEDIKLYDMADVWVKIQDVLQMLLTEYLDMKNT 406
+Q+ + + D Q +Q L TE L +KNT
Sbjct: 1464 ALADWKQKHEESQALLDA---SQKEVQALSTELLKLKNT 1499
>gi|51972208 leucine, glutamate and lysine rich 1 [Homo sapiens]
Length = 388
Score = 34.7 bits (78), Expect = 0.45
Identities = 63/300 (21%), Positives = 122/300 (40%), Gaps = 42/300 (14%)
Query: 61 LIVQHYTELTTAIRTYQSITERITNSRNKIKQVK------ENLLSC-KMLLHCKRDELRK 113
L+ + L T + Y+++ E +T + + +K EN L K LL+ R+E+
Sbjct: 2 LLKEKEDSLMTCQQIYKALQEELTVKEKQEEDIKRRINLAENELEITKTLLNQTREEVLT 61
Query: 114 LWIEGIEHKHVLNLLDEIENIKQVPQKLEQCMASKHYLSATDMLVSAVESLEGPLLQVEG 173
L +++ L L+ ++I+Q+ + L Q + S E +E L +
Sbjct: 62 L-----KNERELMLISHQKSIEQLQETLRQKLLSDDNWK---------EKIEAELAKERA 107
Query: 174 LSDLRLE----LHSKKMNLHLVLIDELHRHLYIKSTSRVVQRNKEKGKISSLVKDASVPL 229
+ E L ++ L L + E H+ + K ++ + + KIS L+ A+ L
Sbjct: 108 QHLVEFEEQALLFKEETKLQLDIEKEKHQDVIQKYKK---EQEELQMKISDLITGATRDL 164
Query: 230 IDVTNLPTPRKFLDTSHYSTAGSSSVREINLQDIKEDLELDPEENSTLFMGILIKGLAKL 289
+ T ++ L SH S+ +E ++++K + F L K +
Sbjct: 165 RQ--EVTTLKEKLHKSHTRYTEESNSKEKEIENLKNLV--------AEFESRLKKEIDSN 214
Query: 290 KKIPETVKAIIERLEQELKQIVKRSTTQVADSGYQRGENV----TVENQPRLLLELLELL 345
+ E ++ +E+ ELK+++ T + + EN TV + EL E L
Sbjct: 215 DSVSENLRKEMEQKSDELKRVMLAQTQLIEQFNQSQEENTFLQETVRRECEERFELTEAL 274
>gi|8924258 gamma-aminobutyric acid (GABA) receptor, theta precursor
[Homo sapiens]
Length = 632
Score = 34.3 bits (77), Expect = 0.58
Identities = 37/142 (26%), Positives = 65/142 (45%), Gaps = 16/142 (11%)
Query: 654 NWMNMAQPKQLRPKREEEEDFIRAAFGKESEVLIGNLGDKLIPPQDILRDVSDLKALANM 713
N++ ++ + +P+R + A + + +V++GN+ D LI +D + + A A +
Sbjct: 350 NYLFYSRGPRRQPRRHRRPRRVIARY-RYQQVVVGNVQDGLINVEDGVSSLPITPAQAPL 408
Query: 714 H--ESLEWLASRTKSAFSNLSTSQMLSPAQD---------SHTNTDLPPVSEQIMQTLSE 762
ESL L S ++ A L+TS+ LSP + +DLP SEQ +
Sbjct: 409 ASPESLGSLTSTSEQA--QLATSESLSPLTSLSGQAPLATGESLSDLPSTSEQARHSYGV 466
Query: 763 LAKSFQDMADRCLLVLHLEVRV 784
FQ AD ++ + RV
Sbjct: 467 RFNGFQ--ADDSIIPTEIRNRV 486
>gi|55769583 progesterone-induced blocking factor 1 [Homo sapiens]
Length = 757
Score = 33.9 bits (76), Expect = 0.76
Identities = 53/239 (22%), Positives = 105/239 (43%), Gaps = 41/239 (17%)
Query: 36 DVEDRENEKGRLEEAYEKCDRDLDELIVQ-----HYTELTTAIRTYQSITERITNSRNKI 90
+++ + +E + YEK +++LDE+I+Q + E + +Y T ++ ++
Sbjct: 515 ELQAQNSEHQARLDIYEKLEKELDEIIMQTAEIENEDEAERVLFSYGYGANVPTTAKRRL 574
Query: 91 KQ-----------VKENLLSCKMLLHCKRDELRKLWIEGIEHKHVLNLLDE-----IENI 134
KQ K+N L K L H ++D++ +L E +LN + IE++
Sbjct: 575 KQSVHLARRVLQLEKQNSLILKDLEH-RKDQVTQLSQELDRANSLLNQTQQPYRYLIESV 633
Query: 135 KQVPQKLEQCMASKHYLSATDMLVSAVESLEGPLLQVEGLSDLRLEL---HSKKMNLHLV 191
+Q K++ S ++ + VS + + LLQ + L LE H +++
Sbjct: 634 RQRDSKIDSLTES---IAQLEKDVSNLNKEKSALLQTKNQMALDLEQLLNHREELAAMKQ 690
Query: 192 LIDELH-RH-----LYIKSTSRVVQRNKEKGKISSLVKDASVPLIDVTNLPTPRKFLDT 244
++ ++H +H L K+ + V N++ K +VP N+ TP+ L T
Sbjct: 691 ILVKMHSKHSENSLLLTKTEPKHVTENQKS-------KTLNVPKEHEDNIFTPKPTLFT 742
>gi|109255234 centrosomal protein 290kDa [Homo sapiens]
Length = 2479
Score = 33.5 bits (75), Expect = 1.00
Identities = 81/376 (21%), Positives = 159/376 (42%), Gaps = 66/376 (17%)
Query: 29 RTLSTSDDVEDRENEKGRLEEAYEKCDRDLDEL------IVQHYTELTTAIR------TY 76
R S +D++ D NE + ++AY K R+ +E+ + + LT+ ++
Sbjct: 1811 RENSLTDNLNDLNNELQKKQKAYNKILREKEEIDQENDELKRQIKRLTSGLQGKPLTDNK 1870
Query: 77 QSITERITNSRNKIK-----QVKENLLSCKMLLHCKRDELR----KLW---IEGIEHK-- 122
QS+ E + K++ +V+E L + K + +R K W IEGI +K
Sbjct: 1871 QSLIEELQRKVKKLENQLEGKVEEVDLKPMKEKNAKEELIRWEEGKKWQAKIEGIRNKLK 1930
Query: 123 ----HVLNLLDEIENIKQVPQKLE-QCMASKHYLSATDMLVS---AVESLEGPLLQVEGL 174
V L ++ +K + K + + + + L T M V + +LE ++E L
Sbjct: 1931 EKEGEVFTLTKQLNTLKDLFAKADKEKLTLQRKLKTTGMTVDQVLGIRALESE-KELEEL 1989
Query: 175 SDLRLELHSK--KMNLHLVL-----IDELH---RHLYIKSTSRVVQRNKE---KGKISSL 221
L+L + M H L +++LH R+L K + Q +K+ K IS +
Sbjct: 1990 KKRNLDLENDILYMRAHQALPRDSVVEDLHLQNRYLQEKLHALEKQFSKDTYSKPSISGI 2049
Query: 222 VKDASVPL---IDVTNLPTPRKFLDTSHYSTAGSSSVREI--NLQDIKEDLELDPEENST 276
D + NL + ++ + + + ++D+KE E +E +
Sbjct: 2050 ESDDHCQREQELQKENLKLSSENIELKFQLEQANKDLPRLKNQVRDLKEMCEFLKKEKAE 2109
Query: 277 L--------FMGILIKGLAKLKKIPETVKAIIERLEQELKQIVKRSTTQVADSGYQRGEN 328
+ G K + +L+K +K ++E++++E +Q+ K S + ++ N
Sbjct: 2110 VQRKLGHVRGSGRSGKTIPELEKTIGLMKKVVEKVQRENEQLKKASGILTS----EKMAN 2165
Query: 329 VTVENQPRLLLELLEL 344
+ EN+ +L EL +L
Sbjct: 2166 IEQENE-KLKAELEKL 2180
>gi|54792740 transmembrane and coiled-coil domain family 2 [Homo
sapiens]
Length = 709
Score = 33.5 bits (75), Expect = 1.00
Identities = 20/88 (22%), Positives = 45/88 (51%), Gaps = 4/88 (4%)
Query: 51 YEKCDRDLDELIVQHYTELTTAIRTYQSITERIT-NSRNKIKQVKENLLSC---KMLLHC 106
YE+ + L++L H E+T + S+ E++ S + + ++E + SC L
Sbjct: 562 YERLEEQLNDLTELHQNEMTNLKQELASMEEKVAYQSYERARDIQEAVESCLTRVTKLEL 621
Query: 107 KRDELRKLWIEGIEHKHVLNLLDEIENI 134
++ + + + +EG+E+ + LL + N+
Sbjct: 622 QQQQQQVVQLEGVENANARALLGKFINV 649
>gi|70166430 GRINL1A combined protein isoform 2 [Homo sapiens]
Length = 445
Score = 33.1 bits (74), Expect = 1.3
Identities = 36/155 (23%), Positives = 67/155 (43%), Gaps = 34/155 (21%)
Query: 35 DDVEDRENEKGRLEEAYEKCDRDLDELIVQHYTELTTAI-----RTYQSITERITNSRNK 89
++ + R E RL E EK L +++H TE++ + YQ + E + R +
Sbjct: 293 EEKDQRIGELDRLIERMEKERHQLQLQLLEHETEMSGELTDSDKERYQQLEEASASLRER 352
Query: 90 IKQVKENLLSCKMLLHCKRDELRKLWIEGIEHKHVLNLLDEIENIKQVPQKLEQCMASKH 149
I+ + + ++HC + K V +++EIE++K +KL+Q K
Sbjct: 353 IRHLDD-------MVHC-------------QQKKVKQMVEEIESLK---KKLQQ----KQ 385
Query: 150 YLSATDMLVSAVESLEGPLLQVEGLSDLRLELHSK 184
L L+ + LEG +++ D E +K
Sbjct: 386 LLIL--QLLEKISFLEGENNELQSRLDYLTETQAK 418
>gi|70166414 GRINL1A combined protein isoform 1 [Homo sapiens]
Length = 550
Score = 33.1 bits (74), Expect = 1.3
Identities = 36/155 (23%), Positives = 67/155 (43%), Gaps = 34/155 (21%)
Query: 35 DDVEDRENEKGRLEEAYEKCDRDLDELIVQHYTELTTAI-----RTYQSITERITNSRNK 89
++ + R E RL E EK L +++H TE++ + YQ + E + R +
Sbjct: 293 EEKDQRIGELDRLIERMEKERHQLQLQLLEHETEMSGELTDSDKERYQQLEEASASLRER 352
Query: 90 IKQVKENLLSCKMLLHCKRDELRKLWIEGIEHKHVLNLLDEIENIKQVPQKLEQCMASKH 149
I+ + + ++HC + K V +++EIE++K +KL+Q K
Sbjct: 353 IRHLDD-------MVHC-------------QQKKVKQMVEEIESLK---KKLQQ----KQ 385
Query: 150 YLSATDMLVSAVESLEGPLLQVEGLSDLRLELHSK 184
L L+ + LEG +++ D E +K
Sbjct: 386 LLIL--QLLEKISFLEGENNELQSRLDYLTETQAK 418
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.132 0.367
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,891,350
Number of Sequences: 37866
Number of extensions: 1392864
Number of successful extensions: 4932
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 89
Number of HSP's that attempted gapping in prelim test: 4835
Number of HSP's gapped (non-prelim): 212
length of query: 974
length of database: 18,247,518
effective HSP length: 112
effective length of query: 862
effective length of database: 14,006,526
effective search space: 12073625412
effective search space used: 12073625412
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.