Guide to the Human Genome
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Search of human proteins with 78486558

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|78486558 dermokine isoform 1 precursor [Homo sapiens]
         (90 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|78486558 dermokine isoform 1 precursor [Homo sapiens]              189   3e-49
gi|186928831 dermokine isoform 6 [Homo sapiens]                       134   1e-32
gi|33504489 dermokine isoform 2 precursor [Homo sapiens]              134   1e-32
gi|186928833 dermokine isoform 7 [Homo sapiens]                       125   9e-30
gi|10835218 topoisomerase (DNA) III alpha [Homo sapiens]               30   0.41 
gi|253970500 Ewing sarcoma breakpoint region 1 isoform 1 [Homo s...    29   0.69 
gi|239756539 PREDICTED: hypothetical protein XP_002344929 [Homo ...    28   1.5  
gi|239751144 PREDICTED: hypothetical protein XP_002347730 [Homo ...    28   1.5  
gi|239745508 PREDICTED: hypothetical protein XP_002343507 [Homo ...    28   1.5  
gi|19923391 homeobox D3 [Homo sapiens]                                 28   2.0  
gi|9665248 transporter 1, ATP-binding cassette, sub-family B [Ho...    27   3.4  
gi|57232746 nuclear receptor interacting protein 1 [Homo sapiens]      27   3.4  
gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma...    26   5.9  
gi|30425553 reticulon 4 receptor-like 1 [Homo sapiens]                 26   5.9  
gi|57864582 hornerin [Homo sapiens]                                    26   7.7  
gi|118572606 hemicentin 1 [Homo sapiens]                               26   7.7  
gi|42794771 thioredoxin domain containing 5 isoform 1 precursor ...    26   7.7  
gi|5729947 neuromedin U [Homo sapiens]                                 26   7.7  
gi|253970506 Ewing sarcoma breakpoint region 1 isoform 5 [Homo s...    25   10.0 
gi|253970504 Ewing sarcoma breakpoint region 1 isoform 4 [Homo s...    25   10.0 
gi|253970502 Ewing sarcoma breakpoint region 1 isoform 3 [Homo s...    25   10.0 
gi|4885225 Ewing sarcoma breakpoint region 1 isoform 2 [Homo sap...    25   10.0 
gi|24497501 forkhead box A1 [Homo sapiens]                             25   10.0 
gi|4503489 ephrin-B3 precursor [Homo sapiens]                          25   10.0 
gi|145199237 transcription elongation factor B polypeptide 3 bin...    25   10.0 

>gi|78486558 dermokine isoform 1 precursor [Homo sapiens]
          Length = 90

 Score =  189 bits (481), Expect = 3e-49
 Identities = 90/90 (100%), Positives = 90/90 (100%)

Query: 1  MNMKPATASALLLLLLGLAWTQGSHGWGADASSLQKRAGRADQNYNYNQHAYPTAYGGKY 60
          MNMKPATASALLLLLLGLAWTQGSHGWGADASSLQKRAGRADQNYNYNQHAYPTAYGGKY
Sbjct: 1  MNMKPATASALLLLLLGLAWTQGSHGWGADASSLQKRAGRADQNYNYNQHAYPTAYGGKY 60

Query: 61 SVKTPAKGGVSPSSSASRVQPGLLQWVKFW 90
          SVKTPAKGGVSPSSSASRVQPGLLQWVKFW
Sbjct: 61 SVKTPAKGGVSPSSSASRVQPGLLQWVKFW 90


>gi|186928831 dermokine isoform 6 [Homo sapiens]
          Length = 189

 Score =  134 bits (338), Expect = 1e-32
 Identities = 63/63 (100%), Positives = 63/63 (100%)

Query: 28  GADASSLQKRAGRADQNYNYNQHAYPTAYGGKYSVKTPAKGGVSPSSSASRVQPGLLQWV 87
           GADASSLQKRAGRADQNYNYNQHAYPTAYGGKYSVKTPAKGGVSPSSSASRVQPGLLQWV
Sbjct: 127 GADASSLQKRAGRADQNYNYNQHAYPTAYGGKYSVKTPAKGGVSPSSSASRVQPGLLQWV 186

Query: 88  KFW 90
           KFW
Sbjct: 187 KFW 189


>gi|33504489 dermokine isoform 2 precursor [Homo sapiens]
          Length = 476

 Score =  134 bits (338), Expect = 1e-32
 Identities = 63/63 (100%), Positives = 63/63 (100%)

Query: 28  GADASSLQKRAGRADQNYNYNQHAYPTAYGGKYSVKTPAKGGVSPSSSASRVQPGLLQWV 87
           GADASSLQKRAGRADQNYNYNQHAYPTAYGGKYSVKTPAKGGVSPSSSASRVQPGLLQWV
Sbjct: 414 GADASSLQKRAGRADQNYNYNQHAYPTAYGGKYSVKTPAKGGVSPSSSASRVQPGLLQWV 473

Query: 88  KFW 90
           KFW
Sbjct: 474 KFW 476


>gi|186928833 dermokine isoform 7 [Homo sapiens]
          Length = 137

 Score =  125 bits (313), Expect = 9e-30
 Identities = 63/77 (81%), Positives = 63/77 (81%), Gaps = 14/77 (18%)

Query: 28  GADASSLQKRAGRADQ--------------NYNYNQHAYPTAYGGKYSVKTPAKGGVSPS 73
           GADASSLQKRAGRADQ              NYNYNQHAYPTAYGGKYSVKTPAKGGVSPS
Sbjct: 61  GADASSLQKRAGRADQPGAGWQEVAAVTSKNYNYNQHAYPTAYGGKYSVKTPAKGGVSPS 120

Query: 74  SSASRVQPGLLQWVKFW 90
           SSASRVQPGLLQWVKFW
Sbjct: 121 SSASRVQPGLLQWVKFW 137


>gi|10835218 topoisomerase (DNA) III alpha [Homo sapiens]
          Length = 1001

 Score = 30.0 bits (66), Expect = 0.41
 Identities = 13/35 (37%), Positives = 20/35 (57%)

Query: 27  WGADASSLQKRAGRADQNYNYNQHAYPTAYGGKYS 61
           WGA A S+ +R G   +N N +  A+P  +  KY+
Sbjct: 389 WGAFAQSILERGGPTPRNGNKSDQAHPPIHPTKYT 423


>gi|253970500 Ewing sarcoma breakpoint region 1 isoform 1 [Homo
          sapiens]
          Length = 661

 Score = 29.3 bits (64), Expect = 0.69
 Identities = 18/59 (30%), Positives = 28/59 (47%), Gaps = 5/59 (8%)

Query: 23 GSHGWGADASSLQKRAGRADQNYNYNQHAYPTAYGGKYSVKTPAKGGVSPSSSASRVQP 81
          G++G   D S  Q     A     Y Q AY T+YG   +V+  + G  +P++  +  QP
Sbjct: 42 GTYGQPTDVSYTQ-----AQTTATYGQTAYATSYGQPPTVEGTSTGYTTPTAPQAYSQP 95


>gi|239756539 PREDICTED: hypothetical protein XP_002344929 [Homo
           sapiens]
          Length = 223

 Score = 28.1 bits (61), Expect = 1.5
 Identities = 23/76 (30%), Positives = 31/76 (40%), Gaps = 3/76 (3%)

Query: 11  LLLLLLGLAWTQGSHGWGADASSLQKRAGRADQNYNYN-QHAYPTAYGGKYSVKTPAKGG 69
           LLLLL G  W    HG G       +RAG   Q  N       P+A   + +    A  G
Sbjct: 68  LLLLLRGQCWILVGHGAGCGGRG--RRAGEWIQGENAGLVTRTPSAARSERNAADLASEG 125

Query: 70  VSPSSSASRVQPGLLQ 85
            +  +   +  PGLL+
Sbjct: 126 AAQEAGRRKAAPGLLK 141


>gi|239751144 PREDICTED: hypothetical protein XP_002347730 [Homo
           sapiens]
          Length = 223

 Score = 28.1 bits (61), Expect = 1.5
 Identities = 23/76 (30%), Positives = 31/76 (40%), Gaps = 3/76 (3%)

Query: 11  LLLLLLGLAWTQGSHGWGADASSLQKRAGRADQNYNYN-QHAYPTAYGGKYSVKTPAKGG 69
           LLLLL G  W    HG G       +RAG   Q  N       P+A   + +    A  G
Sbjct: 68  LLLLLRGQCWILVGHGAGCGGRG--RRAGEWIQGENAGLVTRTPSAARSERNAADLASEG 125

Query: 70  VSPSSSASRVQPGLLQ 85
            +  +   +  PGLL+
Sbjct: 126 AAQEAGRRKAAPGLLK 141


>gi|239745508 PREDICTED: hypothetical protein XP_002343507 [Homo
           sapiens]
          Length = 223

 Score = 28.1 bits (61), Expect = 1.5
 Identities = 23/76 (30%), Positives = 31/76 (40%), Gaps = 3/76 (3%)

Query: 11  LLLLLLGLAWTQGSHGWGADASSLQKRAGRADQNYNYN-QHAYPTAYGGKYSVKTPAKGG 69
           LLLLL G  W    HG G       +RAG   Q  N       P+A   + +    A  G
Sbjct: 68  LLLLLRGQCWILVGHGAGCGGRG--RRAGEWIQGENAGLVTRTPSAARSERNAADLASEG 125

Query: 70  VSPSSSASRVQPGLLQ 85
            +  +   +  PGLL+
Sbjct: 126 AAQEAGRRKAAPGLLK 141


>gi|19923391 homeobox D3 [Homo sapiens]
          Length = 432

 Score = 27.7 bits (60), Expect = 2.0
 Identities = 14/36 (38%), Positives = 20/36 (55%), Gaps = 1/36 (2%)

Query: 53  PTAYGGKYSVKTPAKGGVSPSSSASRVQPGLLQWVK 88
           PT  GG    K P KGG + SSS++ +   +  W+K
Sbjct: 131 PTNPGGGVPAKKP-KGGPNASSSSATISKQIFPWMK 165


>gi|9665248 transporter 1, ATP-binding cassette, sub-family B [Homo
           sapiens]
          Length = 808

 Score = 26.9 bits (58), Expect = 3.4
 Identities = 22/64 (34%), Positives = 30/64 (46%), Gaps = 9/64 (14%)

Query: 3   MKPATASALLLLLLGLAWTQGSHGWGADASSLQKRAGRADQNYNYNQHAYPTAYGGKYSV 62
           +KP  A+AL L L GLA  +    WGA         G AD     +  ++PTA+   Y+ 
Sbjct: 156 LKPL-AAALGLALPGLALFRELISWGA--------PGSADSTRLLHWGSHPTAFVVSYAA 206

Query: 63  KTPA 66
             PA
Sbjct: 207 ALPA 210


>gi|57232746 nuclear receptor interacting protein 1 [Homo sapiens]
          Length = 1158

 Score = 26.9 bits (58), Expect = 3.4
 Identities = 15/46 (32%), Positives = 20/46 (43%)

Query: 9  SALLLLLLGLAWTQGSHGWGADASSLQKRAGRADQNYNYNQHAYPT 54
          S +L  L GL   Q + G G             DQN+N +  A+PT
Sbjct: 15 SIVLTYLEGLLMHQAAGGSGTAVDKKSAGHNEEDQNFNISGSAFPT 60


>gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma)
           [Homo sapiens]
          Length = 526

 Score = 26.2 bits (56), Expect = 5.9
 Identities = 15/59 (25%), Positives = 22/59 (37%)

Query: 23  GSHGWGADASSLQKRAGRADQNYNYNQHAYPTAYGGKYSVKTPAKGGVSPSSSASRVQP 81
           GS G    + S Q   G+      Y Q   P++  G Y   + +     P S +   QP
Sbjct: 76  GSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQP 134


>gi|30425553 reticulon 4 receptor-like 1 [Homo sapiens]
          Length = 441

 Score = 26.2 bits (56), Expect = 5.9
 Identities = 23/66 (34%), Positives = 30/66 (45%), Gaps = 7/66 (10%)

Query: 26  GWGADASSLQKRAGRADQNYNYNQHAYPTAYG---GKYSVKTP--AKGGVSPSSSASRVQ 80
           G G  A  L   A   D  + ++    PTA     GK + +TP  A  GV  +SSAS + 
Sbjct: 369 GAGKQAPELPDYA--PDYQHKFSFDIMPTARPKRKGKCARRTPIRAPSGVQQASSASSLG 426

Query: 81  PGLLQW 86
             LL W
Sbjct: 427 ASLLAW 432


>gi|57864582 hornerin [Homo sapiens]
          Length = 2850

 Score = 25.8 bits (55), Expect = 7.7
 Identities = 20/74 (27%), Positives = 28/74 (37%), Gaps = 8/74 (10%)

Query: 17  GLAWTQGSHGWGADASSLQKRAGRADQNYNYNQHAYPTAYGGKYSVKTPAKG-------- 68
           G + + G HG G+  SS       + Q+  Y QH   + +   Y       G        
Sbjct: 914 GRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQH 973

Query: 69  GVSPSSSASRVQPG 82
           G S  SS+S  Q G
Sbjct: 974 GSSSGSSSSYGQHG 987


>gi|118572606 hemicentin 1 [Homo sapiens]
          Length = 5635

 Score = 25.8 bits (55), Expect = 7.7
 Identities = 14/52 (26%), Positives = 26/52 (50%), Gaps = 1/52 (1%)

Query: 38   AGRADQNYNYNQHAYPTAYGGKYSVKTPA-KGGVSPSSSASRVQPGLLQWVK 88
            AGR D+N++ N +  P+  G +  V        V+ +  A+ + P  + W+K
Sbjct: 3136 AGRDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTCDATGIPPPTIAWLK 3187


>gi|42794771 thioredoxin domain containing 5 isoform 1 precursor
          [Homo sapiens]
          Length = 432

 Score = 25.8 bits (55), Expect = 7.7
 Identities = 15/28 (53%), Positives = 17/28 (60%), Gaps = 3/28 (10%)

Query: 4  KPATASALLLLLLGLAWTQGSHGWGADA 31
          +PA  +ALLLLLLG     G   WGA A
Sbjct: 14 RPAALTALLLLLLGHG---GGGRWGARA 38


>gi|5729947 neuromedin U [Homo sapiens]
          Length = 174

 Score = 25.8 bits (55), Expect = 7.7
 Identities = 13/19 (68%), Positives = 14/19 (73%)

Query: 6  ATASALLLLLLGLAWTQGS 24
          A AS LLLLLL LAW  G+
Sbjct: 17 AAASPLLLLLLLLAWCAGA 35


>gi|253970506 Ewing sarcoma breakpoint region 1 isoform 5 [Homo
          sapiens]
          Length = 354

 Score = 25.4 bits (54), Expect = 10.0
 Identities = 18/59 (30%), Positives = 25/59 (42%), Gaps = 11/59 (18%)

Query: 23 GSHGWGADASSLQKRAGRADQNYNYNQHAYPTAYGGKYSVKTPAKGGVSPSSSASRVQP 81
          G++G   D S  Q     A     Y Q AY T+YG       P  G  +P++  +  QP
Sbjct: 42 GTYGQPTDVSYTQ-----AQTTATYGQTAYATSYG------QPPTGYTTPTAPQAYSQP 89


>gi|253970504 Ewing sarcoma breakpoint region 1 isoform 4 [Homo
          sapiens]
          Length = 600

 Score = 25.4 bits (54), Expect = 10.0
 Identities = 18/59 (30%), Positives = 25/59 (42%), Gaps = 11/59 (18%)

Query: 23 GSHGWGADASSLQKRAGRADQNYNYNQHAYPTAYGGKYSVKTPAKGGVSPSSSASRVQP 81
          G++G   D S  Q     A     Y Q AY T+YG       P  G  +P++  +  QP
Sbjct: 42 GTYGQPTDVSYTQ-----AQTTATYGQTAYATSYG------QPPTGYTTPTAPQAYSQP 89


>gi|253970502 Ewing sarcoma breakpoint region 1 isoform 3 [Homo
          sapiens]
          Length = 655

 Score = 25.4 bits (54), Expect = 10.0
 Identities = 18/59 (30%), Positives = 25/59 (42%), Gaps = 11/59 (18%)

Query: 23 GSHGWGADASSLQKRAGRADQNYNYNQHAYPTAYGGKYSVKTPAKGGVSPSSSASRVQP 81
          G++G   D S  Q     A     Y Q AY T+YG       P  G  +P++  +  QP
Sbjct: 42 GTYGQPTDVSYTQ-----AQTTATYGQTAYATSYG------QPPTGYTTPTAPQAYSQP 89


>gi|4885225 Ewing sarcoma breakpoint region 1 isoform 2 [Homo
          sapiens]
          Length = 656

 Score = 25.4 bits (54), Expect = 10.0
 Identities = 18/59 (30%), Positives = 25/59 (42%), Gaps = 11/59 (18%)

Query: 23 GSHGWGADASSLQKRAGRADQNYNYNQHAYPTAYGGKYSVKTPAKGGVSPSSSASRVQP 81
          G++G   D S  Q     A     Y Q AY T+YG       P  G  +P++  +  QP
Sbjct: 42 GTYGQPTDVSYTQ-----AQTTATYGQTAYATSYG------QPPTGYTTPTAPQAYSQP 89


>gi|24497501 forkhead box A1 [Homo sapiens]
          Length = 472

 Score = 25.4 bits (54), Expect = 10.0
 Identities = 15/35 (42%), Positives = 17/35 (48%), Gaps = 4/35 (11%)

Query: 50  HAYPTAYGGKYSVKTPAKGGVSPSSSASRVQPGLL 84
           H+  TA GG   +KTPA     P SS     PG L
Sbjct: 337 HSGATATGGASELKTPASSTAPPISSG----PGAL 367


>gi|4503489 ephrin-B3 precursor [Homo sapiens]
          Length = 340

 Score = 25.4 bits (54), Expect = 10.0
 Identities = 24/83 (28%), Positives = 38/83 (45%), Gaps = 18/83 (21%)

Query: 5   PATASA---LLLLLLGLAWTQGSHGWGADASSLQKRAGRADQNYNYNQHAYPTAYGGKYS 61
           PA A A   L LLLLG+A   G+  W       ++R  +  +    ++H  P ++G   S
Sbjct: 226 PAVAGAAGGLALLLLGVAGAGGAMCW-------RRRRAKPSE----SRHPGPGSFGRGGS 274

Query: 62  VKTPAKGGVSPSSSASRVQPGLL 84
           +     GG+ P  +    +PG L
Sbjct: 275 LGLGGGGGMGPREA----EPGEL 293


>gi|145199237 transcription elongation factor B polypeptide 3
           binding protein 1 [Homo sapiens]
          Length = 1221

 Score = 25.4 bits (54), Expect = 10.0
 Identities = 19/55 (34%), Positives = 25/55 (45%), Gaps = 1/55 (1%)

Query: 28  GADASSLQKRAGRADQNYNYNQHAYPTAYGGKYSVKTPAKGGVSPSSSASRVQPG 82
           G  ASS +++A R +        A P A  GK     PA+   SP+S  SR   G
Sbjct: 417 GPQASSPRRKAERPEGTKKKPSSATPVATSGKGRPDRPAR-RPSPTSGDSRPAAG 470


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.127    0.402 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 3,654,952
Number of Sequences: 37866
Number of extensions: 137940
Number of successful extensions: 408
Number of sequences better than 10.0: 25
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 397
Number of HSP's gapped (non-prelim): 27
length of query: 90
length of database: 18,247,518
effective HSP length: 62
effective length of query: 28
effective length of database: 15,899,826
effective search space: 445195128
effective search space used: 445195128
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 54 (25.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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