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Search of human proteins with 77812672
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|77812672 exosome component 9 isoform 1 [Homo sapiens]
(456 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|77812672 exosome component 9 isoform 1 [Homo sapiens] 905 0.0
gi|77812670 exosome component 9 isoform 2 [Homo sapiens] 859 0.0
gi|31415882 exosome component 8 [Homo sapiens] 120 2e-27
gi|189083688 exosome component 7 [Homo sapiens] 104 2e-22
gi|61744477 solute carrier family 3, member 2 isoform b [Homo sa... 36 0.063
gi|56550086 WD repeat and HMG-box DNA binding protein 1 isoform ... 35 0.14
gi|5901892 WD repeat and HMG-box DNA binding protein 1 isoform 1... 35 0.14
gi|11067749 bromodomain containing protein 3 [Homo sapiens] 35 0.14
gi|217035093 cyclic nucleotide gated channel alpha 1 isoform 1 [... 35 0.18
gi|61744475 solute carrier family 3, member 2 isoform a [Homo sa... 35 0.18
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 34 0.24
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 34 0.31
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 34 0.31
gi|50727002 pseudouridylate synthase 7 homolog [Homo sapiens] 33 0.41
gi|65506891 solute carrier family 3, member 2 isoform c [Homo sa... 33 0.54
gi|62243734 signal transducing adaptor family member 2 isoform 1... 33 0.70
gi|69354671 ATP-binding cassette, sub-family F, member 1 isoform... 33 0.70
gi|14277682 protocadherin gamma subfamily C, 4 isoform 2 precurs... 32 1.6
gi|11128025 protocadherin gamma subfamily C, 4 isoform 1 precurs... 32 1.6
gi|195963398 suppressor of G2 allele of SKP1 isoform a [Homo sap... 31 2.0
gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens] 31 2.7
gi|66277202 podocalyxin-like isoform 1 precursor [Homo sapiens] 31 2.7
gi|50726968 microfibrillar-associated protein 1 [Homo sapiens] 31 2.7
gi|223941846 zinc finger protein 652 [Homo sapiens] 30 3.5
gi|7662384 zinc finger protein 652 [Homo sapiens] 30 3.5
gi|4506473 v-rel reticuloendotheliosis viral oncogene homolog [H... 30 3.5
gi|16306548 seryl-tRNA synthetase [Homo sapiens] 30 3.5
gi|50962882 G patch domain containing 8 [Homo sapiens] 30 3.5
gi|169213800 PREDICTED: hypothetical protein [Homo sapiens] 30 4.5
gi|169214229 PREDICTED: hypothetical protein [Homo sapiens] 30 4.5
>gi|77812672 exosome component 9 isoform 1 [Homo sapiens]
Length = 456
Score = 905 bits (2339), Expect = 0.0
Identities = 456/456 (100%), Positives = 456/456 (100%)
Query: 1 MKETPLSNCERRFLLRAIEEKKRLDGRQTYDYRNIRISFGTDYGCCIVELGKTRVLGQVS 60
MKETPLSNCERRFLLRAIEEKKRLDGRQTYDYRNIRISFGTDYGCCIVELGKTRVLGQVS
Sbjct: 1 MKETPLSNCERRFLLRAIEEKKRLDGRQTYDYRNIRISFGTDYGCCIVELGKTRVLGQVS 60
Query: 61 CELVSPKLNRATEGILFFNLELSQMAAPAFEPGRQSDLLVKLNRLMERCLRNSKCIDTES 120
CELVSPKLNRATEGILFFNLELSQMAAPAFEPGRQSDLLVKLNRLMERCLRNSKCIDTES
Sbjct: 61 CELVSPKLNRATEGILFFNLELSQMAAPAFEPGRQSDLLVKLNRLMERCLRNSKCIDTES 120
Query: 121 LCVVAGEKVWQIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGDEVTLYTPEER 180
LCVVAGEKVWQIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGDEVTLYTPEER
Sbjct: 121 LCVVAGEKVWQIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGDEVTLYTPEER 180
Query: 181 DPVPLSIHHMPICVSFAFFQQGTYLLVDPNEREERVMDGLLVIAMNKHREICTIQSSGGI 240
DPVPLSIHHMPICVSFAFFQQGTYLLVDPNEREERVMDGLLVIAMNKHREICTIQSSGGI
Sbjct: 181 DPVPLSIHHMPICVSFAFFQQGTYLLVDPNEREERVMDGLLVIAMNKHREICTIQSSGGI 240
Query: 241 MLLKDQVLRCSKIAGVKVAEITELILKALENDQKVRKEGGKFGFAESIANQRITAFKMEK 300
MLLKDQVLRCSKIAGVKVAEITELILKALENDQKVRKEGGKFGFAESIANQRITAFKMEK
Sbjct: 241 MLLKDQVLRCSKIAGVKVAEITELILKALENDQKVRKEGGKFGFAESIANQRITAFKMEK 300
Query: 301 APIDTSDVEEKAEEIIAEAEPPSEVVSTPVLWTPGTAQIGEGVENSWGDLEDSEKEDDEG 360
APIDTSDVEEKAEEIIAEAEPPSEVVSTPVLWTPGTAQIGEGVENSWGDLEDSEKEDDEG
Sbjct: 301 APIDTSDVEEKAEEIIAEAEPPSEVVSTPVLWTPGTAQIGEGVENSWGDLEDSEKEDDEG 360
Query: 361 GGDQAIILDGIKMDTGVEVSDIGSQELGFHHVGQTGLEFLTSDAPIILSDSEEEEMIILE 420
GGDQAIILDGIKMDTGVEVSDIGSQELGFHHVGQTGLEFLTSDAPIILSDSEEEEMIILE
Sbjct: 361 GGDQAIILDGIKMDTGVEVSDIGSQELGFHHVGQTGLEFLTSDAPIILSDSEEEEMIILE 420
Query: 421 PDKNPKKIRTQTTSAKQEKAPSKKPVKRRKKKRAAN 456
PDKNPKKIRTQTTSAKQEKAPSKKPVKRRKKKRAAN
Sbjct: 421 PDKNPKKIRTQTTSAKQEKAPSKKPVKRRKKKRAAN 456
>gi|77812670 exosome component 9 isoform 2 [Homo sapiens]
Length = 439
Score = 859 bits (2220), Expect = 0.0
Identities = 439/456 (96%), Positives = 439/456 (96%), Gaps = 17/456 (3%)
Query: 1 MKETPLSNCERRFLLRAIEEKKRLDGRQTYDYRNIRISFGTDYGCCIVELGKTRVLGQVS 60
MKETPLSNCERRFLLRAIEEKKRLDGRQTYDYRNIRISFGTDYGCCIVELGKTRVLGQVS
Sbjct: 1 MKETPLSNCERRFLLRAIEEKKRLDGRQTYDYRNIRISFGTDYGCCIVELGKTRVLGQVS 60
Query: 61 CELVSPKLNRATEGILFFNLELSQMAAPAFEPGRQSDLLVKLNRLMERCLRNSKCIDTES 120
CELVSPKLNRATEGILFFNLELSQMAAPAFEPGRQSDLLVKLNRLMERCLRNSKCIDTES
Sbjct: 61 CELVSPKLNRATEGILFFNLELSQMAAPAFEPGRQSDLLVKLNRLMERCLRNSKCIDTES 120
Query: 121 LCVVAGEKVWQIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGDEVTLYTPEER 180
LCVVAGEKVWQIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGDEVTLYTPEER
Sbjct: 121 LCVVAGEKVWQIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGDEVTLYTPEER 180
Query: 181 DPVPLSIHHMPICVSFAFFQQGTYLLVDPNEREERVMDGLLVIAMNKHREICTIQSSGGI 240
DPVPLSIHHMPICVSFAFFQQGTYLLVDPNEREERVMDGLLVIAMNKHREICTIQSSGGI
Sbjct: 181 DPVPLSIHHMPICVSFAFFQQGTYLLVDPNEREERVMDGLLVIAMNKHREICTIQSSGGI 240
Query: 241 MLLKDQVLRCSKIAGVKVAEITELILKALENDQKVRKEGGKFGFAESIANQRITAFKMEK 300
MLLKDQVLRCSKIAGVKVAEITELILKALENDQKVRKEGGKFGFAESIANQRITAFKMEK
Sbjct: 241 MLLKDQVLRCSKIAGVKVAEITELILKALENDQKVRKEGGKFGFAESIANQRITAFKMEK 300
Query: 301 APIDTSDVEEKAEEIIAEAEPPSEVVSTPVLWTPGTAQIGEGVENSWGDLEDSEKEDDEG 360
APIDTSDVEEKAEEIIAEAEPPSEVVSTPVLWTPGTAQIGEGVENSWGDLEDSEKEDDEG
Sbjct: 301 APIDTSDVEEKAEEIIAEAEPPSEVVSTPVLWTPGTAQIGEGVENSWGDLEDSEKEDDEG 360
Query: 361 GGDQAIILDGIKMDTGVEVSDIGSQELGFHHVGQTGLEFLTSDAPIILSDSEEEEMIILE 420
GGDQAIILDGIKMDTGVEVSDIGSQ DAPIILSDSEEEEMIILE
Sbjct: 361 GGDQAIILDGIKMDTGVEVSDIGSQ-----------------DAPIILSDSEEEEMIILE 403
Query: 421 PDKNPKKIRTQTTSAKQEKAPSKKPVKRRKKKRAAN 456
PDKNPKKIRTQTTSAKQEKAPSKKPVKRRKKKRAAN
Sbjct: 404 PDKNPKKIRTQTTSAKQEKAPSKKPVKRRKKKRAAN 439
>gi|31415882 exosome component 8 [Homo sapiens]
Length = 276
Score = 120 bits (302), Expect = 2e-27
Identities = 74/259 (28%), Positives = 132/259 (50%), Gaps = 5/259 (1%)
Query: 16 RAIEEKKRLDGRQTYDYRNIRISFG---TDYGCCIVELGKTRVLGQVSCELVSPKLNRAT 72
R ++E R DGR+ ++R ++ G T G +V+LG T V+ V E +P +
Sbjct: 16 RFLKENCRPDGRELGEFRTTTVNIGSISTADGSALVKLGNTTVICGVKAEFAAPSTDAPD 75
Query: 73 EGILFFNLELSQMAAPAFEPGRQSDLLVKLNRLMERCLRNSKCIDTESLCVVAGEKVWQI 132
+G + N++L + + F G + ++ + + NS+ I E LC+ G+ VW +
Sbjct: 76 KGYVVPNVDLPPLCSSRFRSGPPGEEAQVASQFIADVIENSQIIQKEDLCISPGKLVWVL 135
Query: 133 RVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGDEVTLYTPEERDPVPLSIHHMPI 192
DL L++DGNI+DA + A + AL + + P+V++ +E L + L+I P+
Sbjct: 136 YCDLICLDYDGNILDACTFALLAALKNVQLPEVTI-NEETALAEVNLKKKSYLNIRTHPV 194
Query: 193 CVSFAFFQQGTYLLVDPNEREERVMDGLLVIAMNKHREICTIQSSGGIMLLKDQVLRCSK 252
SFA F T L+VDP EE + G L I M++ ++C + GG L ++ C
Sbjct: 195 ATSFAVFDD-TLLIVDPTGEEEHLATGTLTIVMDEEGKLCCLHKPGGSGLTGAKLQDCMS 253
Query: 253 IAGVKVAEITELILKALEN 271
A + E+ +L+ + +++
Sbjct: 254 RAVTRHKEVKKLMDEVIKS 272
>gi|189083688 exosome component 7 [Homo sapiens]
Length = 291
Score = 104 bits (259), Expect = 2e-22
Identities = 78/292 (26%), Positives = 137/292 (46%), Gaps = 11/292 (3%)
Query: 1 MKETPLSNCERRFLLRAIEEKKRLDGRQTYDYRNIRIS---FGTDYGCCIVELGKTRVLG 57
M LS E+ +++ ++E R+DGR DYR + + G V+LG T +L
Sbjct: 1 MASVTLSEAEKVYIVHGVQEDLRVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILV 60
Query: 58 QVSCELVSPKLNRATEGILFFNLELSQMAAPAFEPGRQSDLLVKLNRLMERCLRNSKCID 117
V E+ +PKL + EG L F ++ S A P FE DL ++ + R N +D
Sbjct: 61 GVKAEMGTPKLEKPNEGYLEFFVDCSASATPEFEGRGGDDLGTEIANTLYRIFNNKSSVD 120
Query: 118 TESLCVVAGEKVWQIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSV----QGDEVT 173
++LC+ E W + VD+ LL GN+ DA SIA AL + R P V V +G +
Sbjct: 121 LKTLCISPREHCWVLYVDVLLLECGGNLFDAISIAVKAALFNTRIPRVRVLEDEEGSKDI 180
Query: 174 LYTPEERDPVPLSIHHMPICVSFAFFQQGTYLLVDPNEREERVMDGLLVIAMNKHREICT 233
+ + D + LS+ ++P V+ + G +VD +EE L++++ +
Sbjct: 181 ELSDDPYDCIRLSVENVPCIVTLC--KIGYRHVVDATLQEEACSLASLLVSVTSKGVVTC 238
Query: 234 IQSSGGIMLLKDQVLRCSKIAGVKVAEITELILKA-LENDQKVRKEGGKFGF 284
++ G L + + + G +V ++ L++ + ++ + + K GF
Sbjct: 239 MRKVGKGSLDPESIFEMME-TGKRVGKVLHASLQSVVHKEESLGPKRQKVGF 289
>gi|61744477 solute carrier family 3, member 2 isoform b [Homo
sapiens]
Length = 631
Score = 36.2 bits (82), Expect = 0.063
Identities = 26/91 (28%), Positives = 38/91 (41%), Gaps = 22/91 (24%)
Query: 357 DDEGGGDQAIILDGIKMDTGVEVSDIGSQ------ELGFHHVGQTGLEFLTSDAPIILS- 409
DD G + G+++ + + S+ E GFHHV Q +EFLTS P +
Sbjct: 35 DDSETGSDCVTQAGLQLLASSDPPALASKNAEVTVETGFHHVSQADIEFLTSIDPTASAS 94
Query: 410 ---------------DSEEEEMIILEPDKNP 425
D +E E+ LEP+K P
Sbjct: 95 GSAGITGTMSQDTEVDMKEVELNELEPEKQP 125
>gi|56550086 WD repeat and HMG-box DNA binding protein 1 isoform 2
[Homo sapiens]
Length = 1006
Score = 35.0 bits (79), Expect = 0.14
Identities = 43/215 (20%), Positives = 84/215 (39%), Gaps = 19/215 (8%)
Query: 245 DQVLRCSKIAGVKVAEITELILKALENDQKVRKEGGKFGFAESIANQRITAFKMEKAP-I 303
++ RC ++A + L +K +K+ I Q+++ +EKA +
Sbjct: 653 EREFRCVELADLMTQNAVNLAIKYASRSRKL------------ILAQKLSELAVEKAAEL 700
Query: 304 DTSDVEEKAEEIIAEAEPPSEVVSTPVLWTPGTA--QIGEGVENSWGDLEDSEKEDDEGG 361
+ VEE+ EE + + +T W+ Q+ E E+S G+ +D EK +
Sbjct: 701 TATQVEEEEEEEDFRKKLNAGYSNTATEWSQPRFRNQVEEDAEDS-GEADDEEKPEIHKP 759
Query: 362 GDQAIILDGIKMDTGVEVSDIGSQELGFHHVGQTGLEFLTSDAPIILSDSEEEEMIILEP 421
G + D + + G + + +S P + +S I+
Sbjct: 760 GQNSFSKSTNSSDVSAKSGAVTFSSQGRVNPFKVSA---SSKEPAMSMNSARSTNILDNM 816
Query: 422 DKNPKKIRTQTTSAKQEKAPSKKPVKRRKKKRAAN 456
K+ KK + + EK+P KP+ + K + A+
Sbjct: 817 GKSSKKSTALSRTTNNEKSPIIKPLIPKPKPKQAS 851
>gi|5901892 WD repeat and HMG-box DNA binding protein 1 isoform 1
[Homo sapiens]
Length = 1129
Score = 35.0 bits (79), Expect = 0.14
Identities = 43/215 (20%), Positives = 84/215 (39%), Gaps = 19/215 (8%)
Query: 245 DQVLRCSKIAGVKVAEITELILKALENDQKVRKEGGKFGFAESIANQRITAFKMEKAP-I 303
++ RC ++A + L +K +K+ I Q+++ +EKA +
Sbjct: 776 EREFRCVELADLMTQNAVNLAIKYASRSRKL------------ILAQKLSELAVEKAAEL 823
Query: 304 DTSDVEEKAEEIIAEAEPPSEVVSTPVLWTPGTA--QIGEGVENSWGDLEDSEKEDDEGG 361
+ VEE+ EE + + +T W+ Q+ E E+S G+ +D EK +
Sbjct: 824 TATQVEEEEEEEDFRKKLNAGYSNTATEWSQPRFRNQVEEDAEDS-GEADDEEKPEIHKP 882
Query: 362 GDQAIILDGIKMDTGVEVSDIGSQELGFHHVGQTGLEFLTSDAPIILSDSEEEEMIILEP 421
G + D + + G + + +S P + +S I+
Sbjct: 883 GQNSFSKSTNSSDVSAKSGAVTFSSQGRVNPFKVSA---SSKEPAMSMNSARSTNILDNM 939
Query: 422 DKNPKKIRTQTTSAKQEKAPSKKPVKRRKKKRAAN 456
K+ KK + + EK+P KP+ + K + A+
Sbjct: 940 GKSSKKSTALSRTTNNEKSPIIKPLIPKPKPKQAS 974
>gi|11067749 bromodomain containing protein 3 [Homo sapiens]
Length = 726
Score = 35.0 bits (79), Expect = 0.14
Identities = 34/174 (19%), Positives = 69/174 (39%), Gaps = 15/174 (8%)
Query: 283 GFAESIANQRITAFKMEKAPIDTSDVEEKAEEIIAE--AEPPSEVVSTPVLWTPGTAQIG 340
GFA + +K + + K +++ A+ P E V P L P +
Sbjct: 375 GFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPVEAPALPAPAAPMVS 434
Query: 341 EGVENSWGDLEDSEKEDDEGGGDQAIILDGIKMDTGVEVSDIGSQELGFHHVGQTGLEFL 400
+G E+S E D G D + + ++++ ++L H L
Sbjct: 435 KGAESS---RSSEESSSDSGSSDS-------EEERATRLAEL-QEQLKAVHEQLAALSQA 483
Query: 401 TSDAPIILSDSEEEEMIILEPDKNPKKIRTQTTSAKQEKAPSKKPVKRRKKKRA 454
+ P + +E+E + DK +K + + + +++KA P K+ ++K+A
Sbjct: 484 PVNKPKKKKEKKEKEK--KKKDKEKEKEKHKVKAEEEKKAKVAPPAKQAQQKKA 535
>gi|217035093 cyclic nucleotide gated channel alpha 1 isoform 1
[Homo sapiens]
Length = 759
Score = 34.7 bits (78), Expect = 0.18
Identities = 17/27 (62%), Positives = 19/27 (70%), Gaps = 1/27 (3%)
Query: 386 ELGFHHVGQTGLEFL-TSDAPIILSDS 411
E+GFHHVGQ GLE L +SD P S S
Sbjct: 38 EMGFHHVGQAGLELLISSDLPTSASQS 64
>gi|61744475 solute carrier family 3, member 2 isoform a [Homo
sapiens]
Length = 661
Score = 34.7 bits (78), Expect = 0.18
Identities = 21/56 (37%), Positives = 26/56 (46%), Gaps = 16/56 (28%)
Query: 386 ELGFHHVGQTGLEFLTSDAPIILS----------------DSEEEEMIILEPDKNP 425
E GFHHV Q +EFLTS P + D +E E+ LEP+K P
Sbjct: 100 ETGFHHVSQADIEFLTSIDPTASASGSAGITGTMSQDTEVDMKEVELNELEPEKQP 155
Score = 33.1 bits (74), Expect = 0.54
Identities = 23/51 (45%), Positives = 27/51 (52%), Gaps = 2/51 (3%)
Query: 368 LDGIKMDTGVEVSDIGSQ-ELGFHHVGQTGLEFLTSDAPIILSDSEEEEMI 417
L G + GV+ G ELG H V QTGLE L S P + S S+ EMI
Sbjct: 19 LPGSHSEAGVQGLSAGDDSELGSHCVAQTGLELLASGDP-LPSASQNAEMI 68
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 34.3 bits (77), Expect = 0.24
Identities = 21/74 (28%), Positives = 33/74 (44%)
Query: 290 NQRITAFKMEKAPIDTSDVEEKAEEIIAEAEPPSEVVSTPVLWTPGTAQIGEGVENSWGD 349
N ++ + EK I + D+ +KAE +A+ E P GT + G W D
Sbjct: 612 NVKVHGGRKEKTEILSDDLTDKAEVSEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQD 671
Query: 350 LEDSEKEDDEGGGD 363
E + E D+G G+
Sbjct: 672 EEREKGEKDKGRGE 685
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 33.9 bits (76), Expect = 0.31
Identities = 44/177 (24%), Positives = 68/177 (38%), Gaps = 13/177 (7%)
Query: 286 ESIANQRITAFKMEKAPIDTSDVEEKAEEIIAEAEPPSEVVSTPVLWTPGTAQIGEGVEN 345
+S + +TA E A + +E AEE E E E V+ TA + E
Sbjct: 466 KSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEG 525
Query: 346 SWGDLEDSEKEDDEGGG---DQAIILDGIKMDTGVEVSDIGSQELGFHHVGQTGLEFLTS 402
+ E E+E++E G DQA +G G + G QE G G E
Sbjct: 526 EKEEEEGQEEEEEEDEGAKSDQA--EEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAK 583
Query: 403 DAPIILSDSEE----EEMI----ILEPDKNPKKIRTQTTSAKQEKAPSKKPVKRRKK 451
+ + SEE EE++ + +P+K + K + K PV+ + K
Sbjct: 584 EEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGK 640
Score = 30.0 bits (66), Expect = 4.5
Identities = 36/157 (22%), Positives = 62/157 (39%), Gaps = 19/157 (12%)
Query: 300 KAPIDTSDVEEKAEEIIAEAEPPSEVVSTPVLWTPGTAQIGEGVENSWGDLEDSEKEDDE 359
K+P+ S VEEKA+ S V +PV A++G+G + E+ EKE E
Sbjct: 666 KSPVSKSPVEEKAK---------SPVPKSPVEEAKSKAEVGKGEQK-----EEEEKEVKE 711
Query: 360 GGGDQAIILDGIKMDTGVEVSDIGSQELGFHHVGQTGLEFLTSDAPIILSDSEEEEMIIL 419
++ + K + +V + E + +T + L +EE L
Sbjct: 712 APKEEKV---EKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPL 768
Query: 420 EPDKNPKKIRTQTTSAKQEKAPSKKPVKRRKKKRAAN 456
+ +K +K + +E+ K RK+ A N
Sbjct: 769 QQEKEKEKAGGE--GGSEEEGSDKGAKGSRKEDIAVN 803
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 33.9 bits (76), Expect = 0.31
Identities = 44/177 (24%), Positives = 68/177 (38%), Gaps = 13/177 (7%)
Query: 286 ESIANQRITAFKMEKAPIDTSDVEEKAEEIIAEAEPPSEVVSTPVLWTPGTAQIGEGVEN 345
+S + +TA E A + +E AEE E E E V+ TA + E
Sbjct: 90 KSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEG 149
Query: 346 SWGDLEDSEKEDDEGGG---DQAIILDGIKMDTGVEVSDIGSQELGFHHVGQTGLEFLTS 402
+ E E+E++E G DQA +G G + G QE G G E
Sbjct: 150 EKEEEEGQEEEEEEDEGAKSDQA--EEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAK 207
Query: 403 DAPIILSDSEE----EEMI----ILEPDKNPKKIRTQTTSAKQEKAPSKKPVKRRKK 451
+ + SEE EE++ + +P+K + K + K PV+ + K
Sbjct: 208 EEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGK 264
Score = 30.0 bits (66), Expect = 4.5
Identities = 36/157 (22%), Positives = 62/157 (39%), Gaps = 19/157 (12%)
Query: 300 KAPIDTSDVEEKAEEIIAEAEPPSEVVSTPVLWTPGTAQIGEGVENSWGDLEDSEKEDDE 359
K+P+ S VEEKA+ S V +PV A++G+G + E+ EKE E
Sbjct: 290 KSPVSKSPVEEKAK---------SPVPKSPVEEAKSKAEVGKGEQK-----EEEEKEVKE 335
Query: 360 GGGDQAIILDGIKMDTGVEVSDIGSQELGFHHVGQTGLEFLTSDAPIILSDSEEEEMIIL 419
++ + K + +V + E + +T + L +EE L
Sbjct: 336 APKEEKV---EKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPL 392
Query: 420 EPDKNPKKIRTQTTSAKQEKAPSKKPVKRRKKKRAAN 456
+ +K +K + +E+ K RK+ A N
Sbjct: 393 QQEKEKEKAGGE--GGSEEEGSDKGAKGSRKEDIAVN 427
>gi|50727002 pseudouridylate synthase 7 homolog [Homo sapiens]
Length = 661
Score = 33.5 bits (75), Expect = 0.41
Identities = 21/76 (27%), Positives = 37/76 (48%), Gaps = 4/76 (5%)
Query: 326 VSTPVLWTPGTAQIGEGVENSWGDLEDSEKEDDEGGGDQAIILDGIK----MDTGVEVSD 381
+S V P T G+G +NS LED E+E+++G ++ + M G+ +D
Sbjct: 54 ISEDVPRPPDTVSTGKGGKNSEAQLEDEEEEEEDGLSEECEEEESESFADMMKHGLTEAD 113
Query: 382 IGSQELGFHHVGQTGL 397
+G + H G +G+
Sbjct: 114 VGITKFVSSHQGFSGI 129
>gi|65506891 solute carrier family 3, member 2 isoform c [Homo
sapiens]
Length = 630
Score = 33.1 bits (74), Expect = 0.54
Identities = 23/51 (45%), Positives = 27/51 (52%), Gaps = 2/51 (3%)
Query: 368 LDGIKMDTGVEVSDIGSQ-ELGFHHVGQTGLEFLTSDAPIILSDSEEEEMI 417
L G + GV+ G ELG H V QTGLE L S P + S S+ EMI
Sbjct: 19 LPGSHSEAGVQGLSAGDDSELGSHCVAQTGLELLASGDP-LPSASQNAEMI 68
>gi|62243734 signal transducing adaptor family member 2 isoform 1
[Homo sapiens]
Length = 449
Score = 32.7 bits (73), Expect = 0.70
Identities = 14/20 (70%), Positives = 14/20 (70%)
Query: 386 ELGFHHVGQTGLEFLTSDAP 405
E GFHHV Q GLE LTS P
Sbjct: 359 EKGFHHVAQAGLELLTSSDP 378
>gi|69354671 ATP-binding cassette, sub-family F, member 1 isoform a
[Homo sapiens]
Length = 845
Score = 32.7 bits (73), Expect = 0.70
Identities = 20/60 (33%), Positives = 30/60 (50%), Gaps = 11/60 (18%)
Query: 306 SDVEEKAEEIIAEAEPPSEVVSTPVLWTPGTAQIGEGVENSWGDLEDSEKEDDEGGGDQA 365
++ E+K EEII E EPP + G+ + GEG E+E++EGG +A
Sbjct: 198 NEEEDKEEEIIKEKEPPKQGKEKAKKAEQGSEEEGEG-----------EEEEEEGGESKA 246
>gi|14277682 protocadherin gamma subfamily C, 4 isoform 2 precursor
[Homo sapiens]
Length = 871
Score = 31.6 bits (70), Expect = 1.6
Identities = 29/110 (26%), Positives = 48/110 (43%), Gaps = 21/110 (19%)
Query: 125 AGEKVWQIRVDLHLLNHD----------GNIIDAASIAAIVALCHFRRPDVSVQGDEVTL 174
A E+ +RVDL +N + G + ++A +VAL + PD GD V+L
Sbjct: 329 AMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVALISVQDPDSGSNGD-VSL 387
Query: 175 YTPEERDPVPLSIHHMPICVSFAFFQQGTYLLVDPNEREERVMDGLLVIA 224
P+ H+P + AF Q + + P +RE + ++V A
Sbjct: 388 RIPD----------HLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTA 427
>gi|11128025 protocadherin gamma subfamily C, 4 isoform 1 precursor
[Homo sapiens]
Length = 938
Score = 31.6 bits (70), Expect = 1.6
Identities = 29/110 (26%), Positives = 48/110 (43%), Gaps = 21/110 (19%)
Query: 125 AGEKVWQIRVDLHLLNHD----------GNIIDAASIAAIVALCHFRRPDVSVQGDEVTL 174
A E+ +RVDL +N + G + ++A +VAL + PD GD V+L
Sbjct: 329 AMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVALISVQDPDSGSNGD-VSL 387
Query: 175 YTPEERDPVPLSIHHMPICVSFAFFQQGTYLLVDPNEREERVMDGLLVIA 224
P+ H+P + AF Q + + P +RE + ++V A
Sbjct: 388 RIPD----------HLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTA 427
>gi|195963398 suppressor of G2 allele of SKP1 isoform a [Homo
sapiens]
Length = 365
Score = 31.2 bits (69), Expect = 2.0
Identities = 13/20 (65%), Positives = 14/20 (70%)
Query: 386 ELGFHHVGQTGLEFLTSDAP 405
E GFH VGQ GL+ LTS P
Sbjct: 111 ETGFHRVGQAGLQLLTSSDP 130
>gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens]
Length = 4374
Score = 30.8 bits (68), Expect = 2.7
Identities = 40/177 (22%), Positives = 69/177 (38%), Gaps = 38/177 (21%)
Query: 268 ALENDQKVRKEGGKFGFAESIANQRITAFKMEKAPIDTSDVEEKAEEIIAEAEPPSEVVS 327
A ++ +++ G+ G AE + + + E A D D E + + ++ +P EV+S
Sbjct: 2282 ASQDSSSNQQDPGEPGEAE-VQEEDHDVTQTEVADGDIMDGEAETDSVVIAGQP--EVLS 2338
Query: 328 TPVLWTPGTAQIGEGVENSWGDLEDSEKEDDEGGGDQAIILDGIKMDTGVEVSDIGSQEL 387
+ + VEN DL D E D G G+ II+ D E
Sbjct: 2339 SQEMQ----------VENELEDLIDELLERDGGSGNSTIIVSRSGEDESQE--------- 2379
Query: 388 GFHHVGQTGLEFLTSDAPIILSD------SEEEEMIILEPDKNPKKIRTQTTSAKQE 438
+ L +AP LS + E+ M IL+P+ + + + +S E
Sbjct: 2380 ----------DVLMDEAPSNLSQASTLQANREDSMNILDPEDEEEHTQEEDSSGSNE 2426
>gi|66277202 podocalyxin-like isoform 1 precursor [Homo sapiens]
Length = 558
Score = 30.8 bits (68), Expect = 2.7
Identities = 16/27 (59%), Positives = 17/27 (62%), Gaps = 1/27 (3%)
Query: 386 ELGFHHVGQTGLEFLTS-DAPIILSDS 411
E FHHV Q GLE LTS D P + S S
Sbjct: 237 ETVFHHVSQAGLELLTSGDLPTLASQS 263
>gi|50726968 microfibrillar-associated protein 1 [Homo sapiens]
Length = 439
Score = 30.8 bits (68), Expect = 2.7
Identities = 48/216 (22%), Positives = 88/216 (40%), Gaps = 40/216 (18%)
Query: 275 VRKEGGKFGFAESIANQRITAFKMEKAPIDTSDVEE-------KAEEIIAEAEPPSEVVS 327
VR E G+ + + ++ + + AP+++SD E+ KA+E AE E E S
Sbjct: 22 VRNEKGEISMEKVKVKRYVSGKRPDYAPMESSDEEDEEFQFIKKAKEQEAEPEEQEEDSS 81
Query: 328 TPVLWTPGTAQIGEGVE------------------------NSWG-DLEDSEKEDDEGGG 362
+ +I E VE ++W + EDS +E++E
Sbjct: 82 SDPRLRRLQNRISEDVEERLARHRKIVEPEVVGESDSEVEGDAWRMEREDSSEEEEEEID 141
Query: 363 DQAI-ILDGIKMDTGVEVSDIGSQELGFHHVGQTGLEFLTSDAPIILSDSEEEEMIILEP 421
D+ I G+ E + + + G++G E + +DSE+E +EP
Sbjct: 142 DEEIERRRGMMRQRAQERKNEEMEVMEVEDEGRSGEESESESEYEEYTDSEDE----MEP 197
Query: 422 DKNPKKIRTQ---TTSAKQEKAPSKKPVKRRKKKRA 454
P IR + T ++ +A +K +++ K+ A
Sbjct: 198 RLKPVFIRKKDRVTVQEREAEALKQKELEQEAKRMA 233
>gi|223941846 zinc finger protein 652 [Homo sapiens]
Length = 606
Score = 30.4 bits (67), Expect = 3.5
Identities = 26/107 (24%), Positives = 47/107 (43%), Gaps = 5/107 (4%)
Query: 351 EDSEKEDDEGGGDQAIILDGIKMDTGVEVSDIGSQELGFHHVGQTGLEFLTSDAPIILSD 410
ED E DD ++ + K + + ++ +Q L G+ G+ + + P++ +
Sbjct: 95 EDRENSDDTEEEEEEV---SYKREQIIVEVNLNNQTLNVSK-GEKGVSSQSKETPVLKTS 150
Query: 411 S-EEEEMIILEPDKNPKKIRTQTTSAKQEKAPSKKPVKRRKKKRAAN 456
S EEEE E + K+EK K V +R+ +RAA+
Sbjct: 151 SEEEEEESEEEATDDSNDYGENEKQKKKEKIVEKVSVTQRRTRRAAS 197
>gi|7662384 zinc finger protein 652 [Homo sapiens]
Length = 606
Score = 30.4 bits (67), Expect = 3.5
Identities = 26/107 (24%), Positives = 47/107 (43%), Gaps = 5/107 (4%)
Query: 351 EDSEKEDDEGGGDQAIILDGIKMDTGVEVSDIGSQELGFHHVGQTGLEFLTSDAPIILSD 410
ED E DD ++ + K + + ++ +Q L G+ G+ + + P++ +
Sbjct: 95 EDRENSDDTEEEEEEV---SYKREQIIVEVNLNNQTLNVSK-GEKGVSSQSKETPVLKTS 150
Query: 411 S-EEEEMIILEPDKNPKKIRTQTTSAKQEKAPSKKPVKRRKKKRAAN 456
S EEEE E + K+EK K V +R+ +RAA+
Sbjct: 151 SEEEEEESEEEATDDSNDYGENEKQKKKEKIVEKVSVTQRRTRRAAS 197
>gi|4506473 v-rel reticuloendotheliosis viral oncogene homolog [Homo
sapiens]
Length = 619
Score = 30.4 bits (67), Expect = 3.5
Identities = 16/27 (59%), Positives = 17/27 (62%), Gaps = 1/27 (3%)
Query: 386 ELGFHHVGQTGLEFLTS-DAPIILSDS 411
E GF HV Q GLE LTS D P + S S
Sbjct: 309 ETGFRHVDQDGLELLTSGDPPTLASQS 335
>gi|16306548 seryl-tRNA synthetase [Homo sapiens]
Length = 514
Score = 30.4 bits (67), Expect = 3.5
Identities = 33/138 (23%), Positives = 59/138 (42%), Gaps = 15/138 (10%)
Query: 250 CSKIAGVKVAEITELILKALENDQKVRKEGGKFG--FAESIANQRITAFKMEKAPIDTSD 307
CSK G K+ + + + +D+ V + F A+++AN +++ K + ID +
Sbjct: 60 CSKTIGEKMKK-----KEPVGDDESVPENVLSFDDLTADALANLKVSQIKKVRLLIDEAI 114
Query: 308 VEEKAEEIIAEAEPPSEVVSTPVLWTPGT-----AQIGEGVENSWGDLEDSEKEDDEGGG 362
++ AE I EAE + L P + VE WGD +K
Sbjct: 115 LKCDAERIKLEAERFENLREIGNLLHPSVPISNDEDVDNKVERIWGDCTVRKKYSHV--- 171
Query: 363 DQAIILDGIKMDTGVEVS 380
D +++DG + + G V+
Sbjct: 172 DLVVMVDGFEGEKGAVVA 189
>gi|50962882 G patch domain containing 8 [Homo sapiens]
Length = 1502
Score = 30.4 bits (67), Expect = 3.5
Identities = 32/134 (23%), Positives = 56/134 (41%), Gaps = 10/134 (7%)
Query: 333 TPGTAQ---IGEGVENSWGDLEDSE-KEDDEGGGDQAIILDGIKMD---TGVEVSDIGSQ 385
T GT + IG ++ L+ E + E GG++ + G +MD +G S + Q
Sbjct: 586 TKGTEKPKDIGSSSKDHLQGLDPGEPNKSKEVGGEKIVRSSGGRMDAPASGSACSGLNKQ 645
Query: 386 ELGFHHVGQT---GLEFLTSDAPIILSDSEEEEMIILEPDKNPKKIRTQTTSAKQEKAPS 442
E G H +T G + S +++ + K+ +K + T +
Sbjct: 646 EPGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKAESG 705
Query: 443 KKPVKRRKKKRAAN 456
+K KR+K+KR N
Sbjct: 706 EKSKKRKKRKRKKN 719
>gi|169213800 PREDICTED: hypothetical protein [Homo sapiens]
Length = 142
Score = 30.0 bits (66), Expect = 4.5
Identities = 12/19 (63%), Positives = 14/19 (73%)
Query: 387 LGFHHVGQTGLEFLTSDAP 405
+G +HVGQ GLE LTS P
Sbjct: 1 MGLYHVGQAGLELLTSSDP 19
>gi|169214229 PREDICTED: hypothetical protein [Homo sapiens]
Length = 142
Score = 30.0 bits (66), Expect = 4.5
Identities = 12/19 (63%), Positives = 14/19 (73%)
Query: 387 LGFHHVGQTGLEFLTSDAP 405
+G +HVGQ GLE LTS P
Sbjct: 1 MGLYHVGQAGLELLTSSDP 19
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.135 0.386
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,258,434
Number of Sequences: 37866
Number of extensions: 775635
Number of successful extensions: 3118
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 35
Number of HSP's that attempted gapping in prelim test: 3031
Number of HSP's gapped (non-prelim): 95
length of query: 456
length of database: 18,247,518
effective HSP length: 106
effective length of query: 350
effective length of database: 14,233,722
effective search space: 4981802700
effective search space used: 4981802700
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.