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Search of human proteins with 77812670
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|77812670 exosome component 9 isoform 2 [Homo sapiens]
(439 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|77812670 exosome component 9 isoform 2 [Homo sapiens] 870 0.0
gi|77812672 exosome component 9 isoform 1 [Homo sapiens] 859 0.0
gi|31415882 exosome component 8 [Homo sapiens] 120 2e-27
gi|189083688 exosome component 7 [Homo sapiens] 104 2e-22
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 39 0.012
gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens] 37 0.027
gi|83921609 hypothetical protein LOC127254 [Homo sapiens] 37 0.046
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 34 0.23
gi|56550086 WD repeat and HMG-box DNA binding protein 1 isoform ... 34 0.23
gi|5901892 WD repeat and HMG-box DNA binding protein 1 isoform 1... 34 0.23
gi|11067749 bromodomain containing protein 3 [Homo sapiens] 34 0.23
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)... 34 0.30
gi|69354671 ATP-binding cassette, sub-family F, member 1 isoform... 33 0.67
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 33 0.67
gi|41281453 serine/threonine kinase 2 [Homo sapiens] 32 0.88
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 32 0.88
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 32 1.1
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 32 1.1
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f... 32 1.5
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 32 1.5
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 32 1.5
gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ... 32 1.5
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ... 32 1.5
gi|14277682 protocadherin gamma subfamily C, 4 isoform 2 precurs... 32 1.5
gi|11128025 protocadherin gamma subfamily C, 4 isoform 1 precurs... 32 1.5
gi|34996489 pleckstrin homology domain interacting protein [Homo... 31 1.9
gi|168229156 NFKB activating protein [Homo sapiens] 31 2.5
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 31 2.5
gi|50727002 pseudouridylate synthase 7 homolog [Homo sapiens] 31 2.5
gi|16306548 seryl-tRNA synthetase [Homo sapiens] 30 3.3
>gi|77812670 exosome component 9 isoform 2 [Homo sapiens]
Length = 439
Score = 870 bits (2248), Expect = 0.0
Identities = 439/439 (100%), Positives = 439/439 (100%)
Query: 1 MKETPLSNCERRFLLRAIEEKKRLDGRQTYDYRNIRISFGTDYGCCIVELGKTRVLGQVS 60
MKETPLSNCERRFLLRAIEEKKRLDGRQTYDYRNIRISFGTDYGCCIVELGKTRVLGQVS
Sbjct: 1 MKETPLSNCERRFLLRAIEEKKRLDGRQTYDYRNIRISFGTDYGCCIVELGKTRVLGQVS 60
Query: 61 CELVSPKLNRATEGILFFNLELSQMAAPAFEPGRQSDLLVKLNRLMERCLRNSKCIDTES 120
CELVSPKLNRATEGILFFNLELSQMAAPAFEPGRQSDLLVKLNRLMERCLRNSKCIDTES
Sbjct: 61 CELVSPKLNRATEGILFFNLELSQMAAPAFEPGRQSDLLVKLNRLMERCLRNSKCIDTES 120
Query: 121 LCVVAGEKVWQIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGDEVTLYTPEER 180
LCVVAGEKVWQIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGDEVTLYTPEER
Sbjct: 121 LCVVAGEKVWQIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGDEVTLYTPEER 180
Query: 181 DPVPLSIHHMPICVSFAFFQQGTYLLVDPNEREERVMDGLLVIAMNKHREICTIQSSGGI 240
DPVPLSIHHMPICVSFAFFQQGTYLLVDPNEREERVMDGLLVIAMNKHREICTIQSSGGI
Sbjct: 181 DPVPLSIHHMPICVSFAFFQQGTYLLVDPNEREERVMDGLLVIAMNKHREICTIQSSGGI 240
Query: 241 MLLKDQVLRCSKIAGVKVAEITELILKALENDQKVRKEGGKFGFAESIANQRITAFKMEK 300
MLLKDQVLRCSKIAGVKVAEITELILKALENDQKVRKEGGKFGFAESIANQRITAFKMEK
Sbjct: 241 MLLKDQVLRCSKIAGVKVAEITELILKALENDQKVRKEGGKFGFAESIANQRITAFKMEK 300
Query: 301 APIDTSDVEEKAEEIIAEAEPPSEVVSTPVLWTPGTAQIGEGVENSWGDLEDSEKEDDEG 360
APIDTSDVEEKAEEIIAEAEPPSEVVSTPVLWTPGTAQIGEGVENSWGDLEDSEKEDDEG
Sbjct: 301 APIDTSDVEEKAEEIIAEAEPPSEVVSTPVLWTPGTAQIGEGVENSWGDLEDSEKEDDEG 360
Query: 361 GGDQAIILDGIKMDTGVEVSDIGSQDAPIILSDSEEEEMIILEPDKNPKKIRTQTTSAKQ 420
GGDQAIILDGIKMDTGVEVSDIGSQDAPIILSDSEEEEMIILEPDKNPKKIRTQTTSAKQ
Sbjct: 361 GGDQAIILDGIKMDTGVEVSDIGSQDAPIILSDSEEEEMIILEPDKNPKKIRTQTTSAKQ 420
Query: 421 EKAPSKKPVKRRKKKRAAN 439
EKAPSKKPVKRRKKKRAAN
Sbjct: 421 EKAPSKKPVKRRKKKRAAN 439
>gi|77812672 exosome component 9 isoform 1 [Homo sapiens]
Length = 456
Score = 859 bits (2220), Expect = 0.0
Identities = 439/456 (96%), Positives = 439/456 (96%), Gaps = 17/456 (3%)
Query: 1 MKETPLSNCERRFLLRAIEEKKRLDGRQTYDYRNIRISFGTDYGCCIVELGKTRVLGQVS 60
MKETPLSNCERRFLLRAIEEKKRLDGRQTYDYRNIRISFGTDYGCCIVELGKTRVLGQVS
Sbjct: 1 MKETPLSNCERRFLLRAIEEKKRLDGRQTYDYRNIRISFGTDYGCCIVELGKTRVLGQVS 60
Query: 61 CELVSPKLNRATEGILFFNLELSQMAAPAFEPGRQSDLLVKLNRLMERCLRNSKCIDTES 120
CELVSPKLNRATEGILFFNLELSQMAAPAFEPGRQSDLLVKLNRLMERCLRNSKCIDTES
Sbjct: 61 CELVSPKLNRATEGILFFNLELSQMAAPAFEPGRQSDLLVKLNRLMERCLRNSKCIDTES 120
Query: 121 LCVVAGEKVWQIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGDEVTLYTPEER 180
LCVVAGEKVWQIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGDEVTLYTPEER
Sbjct: 121 LCVVAGEKVWQIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGDEVTLYTPEER 180
Query: 181 DPVPLSIHHMPICVSFAFFQQGTYLLVDPNEREERVMDGLLVIAMNKHREICTIQSSGGI 240
DPVPLSIHHMPICVSFAFFQQGTYLLVDPNEREERVMDGLLVIAMNKHREICTIQSSGGI
Sbjct: 181 DPVPLSIHHMPICVSFAFFQQGTYLLVDPNEREERVMDGLLVIAMNKHREICTIQSSGGI 240
Query: 241 MLLKDQVLRCSKIAGVKVAEITELILKALENDQKVRKEGGKFGFAESIANQRITAFKMEK 300
MLLKDQVLRCSKIAGVKVAEITELILKALENDQKVRKEGGKFGFAESIANQRITAFKMEK
Sbjct: 241 MLLKDQVLRCSKIAGVKVAEITELILKALENDQKVRKEGGKFGFAESIANQRITAFKMEK 300
Query: 301 APIDTSDVEEKAEEIIAEAEPPSEVVSTPVLWTPGTAQIGEGVENSWGDLEDSEKEDDEG 360
APIDTSDVEEKAEEIIAEAEPPSEVVSTPVLWTPGTAQIGEGVENSWGDLEDSEKEDDEG
Sbjct: 301 APIDTSDVEEKAEEIIAEAEPPSEVVSTPVLWTPGTAQIGEGVENSWGDLEDSEKEDDEG 360
Query: 361 GGDQAIILDGIKMDTGVEVSDIGSQ-----------------DAPIILSDSEEEEMIILE 403
GGDQAIILDGIKMDTGVEVSDIGSQ DAPIILSDSEEEEMIILE
Sbjct: 361 GGDQAIILDGIKMDTGVEVSDIGSQELGFHHVGQTGLEFLTSDAPIILSDSEEEEMIILE 420
Query: 404 PDKNPKKIRTQTTSAKQEKAPSKKPVKRRKKKRAAN 439
PDKNPKKIRTQTTSAKQEKAPSKKPVKRRKKKRAAN
Sbjct: 421 PDKNPKKIRTQTTSAKQEKAPSKKPVKRRKKKRAAN 456
>gi|31415882 exosome component 8 [Homo sapiens]
Length = 276
Score = 120 bits (302), Expect = 2e-27
Identities = 74/259 (28%), Positives = 132/259 (50%), Gaps = 5/259 (1%)
Query: 16 RAIEEKKRLDGRQTYDYRNIRISFG---TDYGCCIVELGKTRVLGQVSCELVSPKLNRAT 72
R ++E R DGR+ ++R ++ G T G +V+LG T V+ V E +P +
Sbjct: 16 RFLKENCRPDGRELGEFRTTTVNIGSISTADGSALVKLGNTTVICGVKAEFAAPSTDAPD 75
Query: 73 EGILFFNLELSQMAAPAFEPGRQSDLLVKLNRLMERCLRNSKCIDTESLCVVAGEKVWQI 132
+G + N++L + + F G + ++ + + NS+ I E LC+ G+ VW +
Sbjct: 76 KGYVVPNVDLPPLCSSRFRSGPPGEEAQVASQFIADVIENSQIIQKEDLCISPGKLVWVL 135
Query: 133 RVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGDEVTLYTPEERDPVPLSIHHMPI 192
DL L++DGNI+DA + A + AL + + P+V++ +E L + L+I P+
Sbjct: 136 YCDLICLDYDGNILDACTFALLAALKNVQLPEVTI-NEETALAEVNLKKKSYLNIRTHPV 194
Query: 193 CVSFAFFQQGTYLLVDPNEREERVMDGLLVIAMNKHREICTIQSSGGIMLLKDQVLRCSK 252
SFA F T L+VDP EE + G L I M++ ++C + GG L ++ C
Sbjct: 195 ATSFAVFDD-TLLIVDPTGEEEHLATGTLTIVMDEEGKLCCLHKPGGSGLTGAKLQDCMS 253
Query: 253 IAGVKVAEITELILKALEN 271
A + E+ +L+ + +++
Sbjct: 254 RAVTRHKEVKKLMDEVIKS 272
>gi|189083688 exosome component 7 [Homo sapiens]
Length = 291
Score = 104 bits (259), Expect = 2e-22
Identities = 78/292 (26%), Positives = 137/292 (46%), Gaps = 11/292 (3%)
Query: 1 MKETPLSNCERRFLLRAIEEKKRLDGRQTYDYRNIRIS---FGTDYGCCIVELGKTRVLG 57
M LS E+ +++ ++E R+DGR DYR + + G V+LG T +L
Sbjct: 1 MASVTLSEAEKVYIVHGVQEDLRVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILV 60
Query: 58 QVSCELVSPKLNRATEGILFFNLELSQMAAPAFEPGRQSDLLVKLNRLMERCLRNSKCID 117
V E+ +PKL + EG L F ++ S A P FE DL ++ + R N +D
Sbjct: 61 GVKAEMGTPKLEKPNEGYLEFFVDCSASATPEFEGRGGDDLGTEIANTLYRIFNNKSSVD 120
Query: 118 TESLCVVAGEKVWQIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSV----QGDEVT 173
++LC+ E W + VD+ LL GN+ DA SIA AL + R P V V +G +
Sbjct: 121 LKTLCISPREHCWVLYVDVLLLECGGNLFDAISIAVKAALFNTRIPRVRVLEDEEGSKDI 180
Query: 174 LYTPEERDPVPLSIHHMPICVSFAFFQQGTYLLVDPNEREERVMDGLLVIAMNKHREICT 233
+ + D + LS+ ++P V+ + G +VD +EE L++++ +
Sbjct: 181 ELSDDPYDCIRLSVENVPCIVTLC--KIGYRHVVDATLQEEACSLASLLVSVTSKGVVTC 238
Query: 234 IQSSGGIMLLKDQVLRCSKIAGVKVAEITELILKA-LENDQKVRKEGGKFGF 284
++ G L + + + G +V ++ L++ + ++ + + K GF
Sbjct: 239 MRKVGKGSLDPESIFEMME-TGKRVGKVLHASLQSVVHKEESLGPKRQKVGF 289
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 38.5 bits (88), Expect = 0.012
Identities = 38/133 (28%), Positives = 53/133 (39%), Gaps = 10/133 (7%)
Query: 297 KMEKAPIDTSDVEEKAEEIIAEAEPPSEVVSTP---VLWTPGTAQIGEGVENSWGDLEDS 353
K K +SD E+ +EE PP++ + P V PG A +S E+S
Sbjct: 76 KKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASESSS---SEES 132
Query: 354 EKEDDEGGGDQAIILDGIKMDTGVEVSDIGSQDAPIILSDSEEEEMIILEPDKNPKKIRT 413
+DDE + + G+K + + SDS E+ EP KN K T
Sbjct: 133 SDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSED----EPPKNQKPKIT 188
Query: 414 QTTSAKQEKAPSK 426
T Q KAP K
Sbjct: 189 PVTVKAQTKAPPK 201
>gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens]
Length = 4374
Score = 37.4 bits (85), Expect = 0.027
Identities = 40/160 (25%), Positives = 69/160 (43%), Gaps = 21/160 (13%)
Query: 268 ALENDQKVRKEGGKFGFAESIANQRITAFKMEKAPIDTSDVEEKAEEIIAEAEPPSEVVS 327
A ++ +++ G+ G AE + + + E A D D E + + ++ +P EV+S
Sbjct: 2282 ASQDSSSNQQDPGEPGEAE-VQEEDHDVTQTEVADGDIMDGEAETDSVVIAGQP--EVLS 2338
Query: 328 TPVLWTPGTAQIGEGVENSWGDLEDSEKEDDEGGGDQAIILDGIKMDTGVEVSDIGSQDA 387
+ + VEN DL D E D G G+ II+ D E D+ +A
Sbjct: 2339 SQEMQ----------VENELEDLIDELLERDGGSGNSTIIVSRSGEDESQE--DVLMDEA 2386
Query: 388 PIILSD------SEEEEMIILEPDKNPKKIRTQTTSAKQE 421
P LS + E+ M IL+P+ + + + +S E
Sbjct: 2387 PSNLSQASTLQANREDSMNILDPEDEEEHTQEEDSSGSNE 2426
>gi|83921609 hypothetical protein LOC127254 [Homo sapiens]
Length = 1530
Score = 36.6 bits (83), Expect = 0.046
Identities = 39/170 (22%), Positives = 72/170 (42%), Gaps = 14/170 (8%)
Query: 256 VKVAEITELILKALENDQKVRKEGGKFGFAESIANQRITAFKMEKAPIDTSDVEEKAEEI 315
V + E T K+LEN +RKEGG E ++ R T K D ++ +
Sbjct: 1154 VPIFEATPGFEKSLENITALRKEGG----GERLSEARDTEHK------DREELSSRENRA 1203
Query: 316 IAEA--EPPSEVVSTPVLWTPGTAQIGEGVENSWGDLED-SEKEDDEGGGDQAIILDGIK 372
+ E + ++ P G Q EG+ + G E+ + K+ D G +
Sbjct: 1204 LKEGHRQDGEGALAAPEAEPAGKVQAPEGLIPATGQAEELAAKDHDSCAGLEGRAEGQGG 1263
Query: 373 MDTGVEVSDIGSQDAPIILSDSEEEEMIILEPDKNPKKIRTQTTSAKQEK 422
+D + + +++ P I+++ EE + +P++ K T T A Q++
Sbjct: 1264 VDVVLRTQEAVAEEDP-IMAEKFREEAVDEDPEEEEDKECTLETEAMQDR 1312
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 34.3 bits (77), Expect = 0.23
Identities = 21/74 (28%), Positives = 33/74 (44%)
Query: 290 NQRITAFKMEKAPIDTSDVEEKAEEIIAEAEPPSEVVSTPVLWTPGTAQIGEGVENSWGD 349
N ++ + EK I + D+ +KAE +A+ E P GT + G W D
Sbjct: 612 NVKVHGGRKEKTEILSDDLTDKAEVSEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQD 671
Query: 350 LEDSEKEDDEGGGD 363
E + E D+G G+
Sbjct: 672 EEREKGEKDKGRGE 685
>gi|56550086 WD repeat and HMG-box DNA binding protein 1 isoform 2
[Homo sapiens]
Length = 1006
Score = 34.3 bits (77), Expect = 0.23
Identities = 42/212 (19%), Positives = 80/212 (37%), Gaps = 30/212 (14%)
Query: 245 DQVLRCSKIAGVKVAEITELILKALENDQKVRKEGGKFGFAESIANQRITAFKMEKAP-I 303
++ RC ++A + L +K +K+ I Q+++ +EKA +
Sbjct: 653 EREFRCVELADLMTQNAVNLAIKYASRSRKL------------ILAQKLSELAVEKAAEL 700
Query: 304 DTSDVEEKAEEIIAEAEPPSEVVSTPVLWTPGTA--QIGEGVENSWGDLEDSEKEDDEGG 361
+ VEE+ EE + + +T W+ Q+ E E+S G+ +D EK +
Sbjct: 701 TATQVEEEEEEEDFRKKLNAGYSNTATEWSQPRFRNQVEEDAEDS-GEADDEEKPEIHKP 759
Query: 362 GDQAIILDGIKMDTGVEVSDI--------------GSQDAPIILSDSEEEEMIILEPDKN 407
G + D + + S P + +S I+ K+
Sbjct: 760 GQNSFSKSTNSSDVSAKSGAVTFSSQGRVNPFKVSASSKEPAMSMNSARSTNILDNMGKS 819
Query: 408 PKKIRTQTTSAKQEKAPSKKPVKRRKKKRAAN 439
KK + + EK+P KP+ + K + A+
Sbjct: 820 SKKSTALSRTTNNEKSPIIKPLIPKPKPKQAS 851
>gi|5901892 WD repeat and HMG-box DNA binding protein 1 isoform 1
[Homo sapiens]
Length = 1129
Score = 34.3 bits (77), Expect = 0.23
Identities = 42/212 (19%), Positives = 80/212 (37%), Gaps = 30/212 (14%)
Query: 245 DQVLRCSKIAGVKVAEITELILKALENDQKVRKEGGKFGFAESIANQRITAFKMEKAP-I 303
++ RC ++A + L +K +K+ I Q+++ +EKA +
Sbjct: 776 EREFRCVELADLMTQNAVNLAIKYASRSRKL------------ILAQKLSELAVEKAAEL 823
Query: 304 DTSDVEEKAEEIIAEAEPPSEVVSTPVLWTPGTA--QIGEGVENSWGDLEDSEKEDDEGG 361
+ VEE+ EE + + +T W+ Q+ E E+S G+ +D EK +
Sbjct: 824 TATQVEEEEEEEDFRKKLNAGYSNTATEWSQPRFRNQVEEDAEDS-GEADDEEKPEIHKP 882
Query: 362 GDQAIILDGIKMDTGVEVSDI--------------GSQDAPIILSDSEEEEMIILEPDKN 407
G + D + + S P + +S I+ K+
Sbjct: 883 GQNSFSKSTNSSDVSAKSGAVTFSSQGRVNPFKVSASSKEPAMSMNSARSTNILDNMGKS 942
Query: 408 PKKIRTQTTSAKQEKAPSKKPVKRRKKKRAAN 439
KK + + EK+P KP+ + K + A+
Sbjct: 943 SKKSTALSRTTNNEKSPIIKPLIPKPKPKQAS 974
>gi|11067749 bromodomain containing protein 3 [Homo sapiens]
Length = 726
Score = 34.3 bits (77), Expect = 0.23
Identities = 30/157 (19%), Positives = 58/157 (36%), Gaps = 12/157 (7%)
Query: 283 GFAESIANQRITAFKMEKAPIDTSDVEEKAEEIIAE--AEPPSEVVSTPVLWTPGTAQIG 340
GFA + +K + + K +++ A+ P E V P L P +
Sbjct: 375 GFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPVEAPALPAPAAPMVS 434
Query: 341 EGVENSWGDLEDSEKEDDEGGGDQAIILDGIKMDTGVEVSDIGSQDAPIILSDSEEEEMI 400
+G E+S E D G D + + ++++ Q + + +
Sbjct: 435 KGAESS---RSSEESSSDSGSSDS-------EEERATRLAELQEQLKAVHEQLAALSQAP 484
Query: 401 ILEPDKNPKKIRTQTTSAKQEKAPSKKPVKRRKKKRA 437
+ +P K +K + +EK K VK ++K+A
Sbjct: 485 VNKPKKKKEKKEKEKKKKDKEKEKEKHKVKAEEEKKA 521
>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
[Homo sapiens]
Length = 2073
Score = 33.9 bits (76), Expect = 0.30
Identities = 34/134 (25%), Positives = 51/134 (38%), Gaps = 15/134 (11%)
Query: 307 DVEEKAEEIIAEAEPPSEVVSTPVLWTPGTA-------------QIGEGVENSWGDLEDS 353
+V+E E ++ + E E PV +P T+ + E E + E+
Sbjct: 1310 EVKETGEALLPQEENRREETCAPV--SPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEE 1367
Query: 354 EKEDDEGGGDQAIILDGIKMDTGVEVSDIGSQDAPIILSDSEEEEMIILEPDKNPKKIRT 413
E E++EGGG+ DG K E ++ L D EEEE EP N
Sbjct: 1368 EGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDAD 1427
Query: 414 QTTSAKQEKAPSKK 427
+ E A +K
Sbjct: 1428 DEDDSHMESAEVEK 1441
>gi|69354671 ATP-binding cassette, sub-family F, member 1 isoform a
[Homo sapiens]
Length = 845
Score = 32.7 bits (73), Expect = 0.67
Identities = 20/60 (33%), Positives = 30/60 (50%), Gaps = 11/60 (18%)
Query: 306 SDVEEKAEEIIAEAEPPSEVVSTPVLWTPGTAQIGEGVENSWGDLEDSEKEDDEGGGDQA 365
++ E+K EEII E EPP + G+ + GEG E+E++EGG +A
Sbjct: 198 NEEEDKEEEIIKEKEPPKQGKEKAKKAEQGSEEEGEG-----------EEEEEEGGESKA 246
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 32.7 bits (73), Expect = 0.67
Identities = 22/100 (22%), Positives = 45/100 (45%), Gaps = 2/100 (2%)
Query: 338 QIGEGVENSWGDLEDSEKEDDEGGGDQAIILDGIKMDTGVEVSDIGSQDAPIILSDSEEE 397
++ E E G + S++++ + ++ + + +DTGV + + P D E
Sbjct: 252 KLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEG 311
Query: 398 EMIILEPDKNPKKIRTQTTSAKQEKAPSKKPVKRRKKKRA 437
+ + DK KK + +++K PSK VK ++ A
Sbjct: 312 DK--KKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALA 349
>gi|41281453 serine/threonine kinase 2 [Homo sapiens]
Length = 1235
Score = 32.3 bits (72), Expect = 0.88
Identities = 37/138 (26%), Positives = 57/138 (41%), Gaps = 18/138 (13%)
Query: 286 ESIANQRITAFKMEKAPIDTSDVEEKAEEIIAEAEPPSEVVSTPVLWTPGTAQIGEGVEN 345
E + R T ++ + P T D + E+IAEA+ A++ E VE+
Sbjct: 274 EKNVDARWTTSQLLQHPFVTVDSNKPIRELIAEAK----------------AEVTEEVED 317
Query: 346 SWGDLEDSEKEDDEGGGDQAIILDGIKMDTGVEVSDIGSQDAPIILSDSEEEEMIILEPD 405
G ED E+E + A + D SQ+A I+ S SE+ E E
Sbjct: 318 --GKEEDEEEETENSLPIPASKRASSDLSIASSEEDKLSQNACILESVSEKTERSNSEDK 375
Query: 406 KNPKKIRTQTTSAKQEKA 423
N K + + T+ + EKA
Sbjct: 376 LNSKILNEKPTTDEPEKA 393
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 32.3 bits (72), Expect = 0.88
Identities = 37/161 (22%), Positives = 60/161 (37%), Gaps = 8/161 (4%)
Query: 270 ENDQKVRKEGGKFGFAESIANQRITAFKMEKAPIDTSDVEEKAEEIIAEAEPPSEVVSTP 329
E D + +G + AE A + + + + A+E EA+P SE V P
Sbjct: 2045 EGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAP 2104
Query: 330 VLWTPGTAQIGEGVENSWGDLEDSEKEDDEGGGDQAIILDGIKMDTGVEVSDIGSQDAPI 389
G AQ EG+E + E + + EG + GVE D + P
Sbjct: 2105 E--AEGEAQKAEGIEAP--ETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQP- 2159
Query: 390 ILSDSEEEEMIILEPDKNPKKIRTQTTSAKQEKAPSKKPVK 430
+SE E E + P+ + A+ E P + ++
Sbjct: 2160 ---ESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIE 2197
Score = 28.9 bits (63), Expect = 9.7
Identities = 34/142 (23%), Positives = 55/142 (38%), Gaps = 17/142 (11%)
Query: 300 KAPIDTSDVEEKAEEIIAEAEPPSEVVSTP-VLW----------TPGTAQIGEGVENSWG 348
+A ++ DVE A E EA+P SE V TP W P + + S
Sbjct: 1866 EAQPESEDVE--APEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVE 1923
Query: 349 DLEDSEKEDDEGGGDQAIILDGIKMDTGVEVSDIGSQDAPIILSDSEEEEMIILEPDKNP 408
LE +++ E G +A + + E ++ +I S EEE D
Sbjct: 1924 ALETEGEDEPESEGAEAQEAE----EAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEA 1979
Query: 409 KKIRTQTTSAKQEKAPSKKPVK 430
++ +T A+ E P + V+
Sbjct: 1980 LEVEVETQEAEGEAQPESEDVE 2001
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 32.0 bits (71), Expect = 1.1
Identities = 40/153 (26%), Positives = 62/153 (40%), Gaps = 7/153 (4%)
Query: 286 ESIANQRITAFKMEKAPIDTSDVEEKAEEIIAEAEPPSEVVSTPVLWTPGTAQIGEGVEN 345
+S + +TA E A + +E AEE E E E V+ TA + E
Sbjct: 466 KSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEG 525
Query: 346 SWGDLEDSEKEDDEGGG---DQAIILDGIKMDTGVEVSDIGSQDAPIILSDSEEEEMIIL 402
+ E E+E++E G DQA +G G + G Q+ +++E EE
Sbjct: 526 EKEEEEGQEEEEEEDEGAKSDQA--EEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAK 583
Query: 403 EPDKNPKKIRTQTTSAKQEKAPSKKPVKRRKKK 435
E K +K ++ + K+E K K K K
Sbjct: 584 EEKKVEEK--SEEVATKEELVADAKVEKPEKAK 614
Score = 29.3 bits (64), Expect = 7.4
Identities = 32/156 (20%), Positives = 63/156 (40%), Gaps = 17/156 (10%)
Query: 286 ESIANQRITAFKMEKAPIDTSDVEEKAEEIIAEAEPPSEVVSTPVLWTP----GTAQIGE 341
E +A+ ++ + K+P+ S VEEK + + ++ P E +PV +P G + + +
Sbjct: 600 ELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKS-PVEEKGKSPVPKSPVEEKGKSPVPK 658
Query: 342 GVENSWGDLEDSEKEDDEGGGDQAIILDGIKMDTGVEVSDIGSQDAPIILSDSEEEEMII 401
G S+ +E K + V S + + + E++E
Sbjct: 659 SPVEEKGKSPVSKSPVEE------------KAKSPVPKSPVEEAKSKAEVGKGEQKEEEE 706
Query: 402 LEPDKNPKKIRTQTTSAKQEKAPSKKPVKRRKKKRA 437
E + PK+ + + K + P KK + K+ A
Sbjct: 707 KEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEA 742
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 32.0 bits (71), Expect = 1.1
Identities = 40/153 (26%), Positives = 62/153 (40%), Gaps = 7/153 (4%)
Query: 286 ESIANQRITAFKMEKAPIDTSDVEEKAEEIIAEAEPPSEVVSTPVLWTPGTAQIGEGVEN 345
+S + +TA E A + +E AEE E E E V+ TA + E
Sbjct: 90 KSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEG 149
Query: 346 SWGDLEDSEKEDDEGGG---DQAIILDGIKMDTGVEVSDIGSQDAPIILSDSEEEEMIIL 402
+ E E+E++E G DQA +G G + G Q+ +++E EE
Sbjct: 150 EKEEEEGQEEEEEEDEGAKSDQA--EEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAK 207
Query: 403 EPDKNPKKIRTQTTSAKQEKAPSKKPVKRRKKK 435
E K +K ++ + K+E K K K K
Sbjct: 208 EEKKVEEK--SEEVATKEELVADAKVEKPEKAK 238
Score = 29.3 bits (64), Expect = 7.4
Identities = 32/156 (20%), Positives = 63/156 (40%), Gaps = 17/156 (10%)
Query: 286 ESIANQRITAFKMEKAPIDTSDVEEKAEEIIAEAEPPSEVVSTPVLWTP----GTAQIGE 341
E +A+ ++ + K+P+ S VEEK + + ++ P E +PV +P G + + +
Sbjct: 224 ELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKS-PVEEKGKSPVPKSPVEEKGKSPVPK 282
Query: 342 GVENSWGDLEDSEKEDDEGGGDQAIILDGIKMDTGVEVSDIGSQDAPIILSDSEEEEMII 401
G S+ +E K + V S + + + E++E
Sbjct: 283 SPVEEKGKSPVSKSPVEE------------KAKSPVPKSPVEEAKSKAEVGKGEQKEEEE 330
Query: 402 LEPDKNPKKIRTQTTSAKQEKAPSKKPVKRRKKKRA 437
E + PK+ + + K + P KK + K+ A
Sbjct: 331 KEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEA 366
>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
[Homo sapiens]
Length = 1412
Score = 31.6 bits (70), Expect = 1.5
Identities = 17/67 (25%), Positives = 35/67 (52%), Gaps = 2/67 (2%)
Query: 372 KMDTGVEVSDIGSQDAPIILSDSEEEEMIILEPDKNPKKIRTQTTSAKQEKAPSKKPVKR 431
++ G+ + G Q P + ++ + + +K KK + + S K ++PS+K K+
Sbjct: 1344 ELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQK--KK 1401
Query: 432 RKKKRAA 438
+KKK+ A
Sbjct: 1402 KKKKKTA 1408
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 31.6 bits (70), Expect = 1.5
Identities = 17/67 (25%), Positives = 35/67 (52%), Gaps = 2/67 (2%)
Query: 372 KMDTGVEVSDIGSQDAPIILSDSEEEEMIILEPDKNPKKIRTQTTSAKQEKAPSKKPVKR 431
++ G+ + G Q P + ++ + + +K KK + + S K ++PS+K K+
Sbjct: 1383 ELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQK--KK 1440
Query: 432 RKKKRAA 438
+KKK+ A
Sbjct: 1441 KKKKKTA 1447
>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
[Homo sapiens]
Length = 1488
Score = 31.6 bits (70), Expect = 1.5
Identities = 17/67 (25%), Positives = 35/67 (52%), Gaps = 2/67 (2%)
Query: 372 KMDTGVEVSDIGSQDAPIILSDSEEEEMIILEPDKNPKKIRTQTTSAKQEKAPSKKPVKR 431
++ G+ + G Q P + ++ + + +K KK + + S K ++PS+K K+
Sbjct: 1420 ELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQK--KK 1477
Query: 432 RKKKRAA 438
+KKK+ A
Sbjct: 1478 KKKKKTA 1484
>gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b [Homo
sapiens]
Length = 1411
Score = 31.6 bits (70), Expect = 1.5
Identities = 17/67 (25%), Positives = 35/67 (52%), Gaps = 2/67 (2%)
Query: 372 KMDTGVEVSDIGSQDAPIILSDSEEEEMIILEPDKNPKKIRTQTTSAKQEKAPSKKPVKR 431
++ G+ + G Q P + ++ + + +K KK + + S K ++PS+K K+
Sbjct: 1343 ELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQK--KK 1400
Query: 432 RKKKRAA 438
+KKK+ A
Sbjct: 1401 KKKKKTA 1407
>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a [Homo
sapiens]
Length = 1450
Score = 31.6 bits (70), Expect = 1.5
Identities = 17/67 (25%), Positives = 35/67 (52%), Gaps = 2/67 (2%)
Query: 372 KMDTGVEVSDIGSQDAPIILSDSEEEEMIILEPDKNPKKIRTQTTSAKQEKAPSKKPVKR 431
++ G+ + G Q P + ++ + + +K KK + + S K ++PS+K K+
Sbjct: 1382 ELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQK--KK 1439
Query: 432 RKKKRAA 438
+KKK+ A
Sbjct: 1440 KKKKKTA 1446
>gi|14277682 protocadherin gamma subfamily C, 4 isoform 2 precursor
[Homo sapiens]
Length = 871
Score = 31.6 bits (70), Expect = 1.5
Identities = 29/110 (26%), Positives = 48/110 (43%), Gaps = 21/110 (19%)
Query: 125 AGEKVWQIRVDLHLLNHD----------GNIIDAASIAAIVALCHFRRPDVSVQGDEVTL 174
A E+ +RVDL +N + G + ++A +VAL + PD GD V+L
Sbjct: 329 AMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVALISVQDPDSGSNGD-VSL 387
Query: 175 YTPEERDPVPLSIHHMPICVSFAFFQQGTYLLVDPNEREERVMDGLLVIA 224
P+ H+P + AF Q + + P +RE + ++V A
Sbjct: 388 RIPD----------HLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTA 427
>gi|11128025 protocadherin gamma subfamily C, 4 isoform 1 precursor
[Homo sapiens]
Length = 938
Score = 31.6 bits (70), Expect = 1.5
Identities = 29/110 (26%), Positives = 48/110 (43%), Gaps = 21/110 (19%)
Query: 125 AGEKVWQIRVDLHLLNHD----------GNIIDAASIAAIVALCHFRRPDVSVQGDEVTL 174
A E+ +RVDL +N + G + ++A +VAL + PD GD V+L
Sbjct: 329 AMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVALISVQDPDSGSNGD-VSL 387
Query: 175 YTPEERDPVPLSIHHMPICVSFAFFQQGTYLLVDPNEREERVMDGLLVIA 224
P+ H+P + AF Q + + P +RE + ++V A
Sbjct: 388 RIPD----------HLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTA 427
>gi|34996489 pleckstrin homology domain interacting protein [Homo
sapiens]
Length = 1821
Score = 31.2 bits (69), Expect = 1.9
Identities = 34/140 (24%), Positives = 52/140 (37%), Gaps = 10/140 (7%)
Query: 305 TSDVEEKAEEIIAEAEPPSEVVSTPVLWTPGTAQIGEGVENSWGDLEDSEK--EDDEGGG 362
T+ + + E PSE + ++ GE V S G E+ E+ D
Sbjct: 791 TNQHNYRTRSALEETPRPSEEIENG----SSSSDEGEVVAVSGGTSEEEERAWHSDGSSS 846
Query: 363 DQAIILDGIKMDTGVEVSD---IGSQDAPIILSDSEEEEMIILEPDKNPKKIRTQTTSAK 419
D + D G+ + + S S+EEE + K KK + + K
Sbjct: 847 DYSSDYSDWTADAGINLQPPKKVPKNKTKKAESSSDEEEESEKQKQKQIKKEKKKVNEEK 906
Query: 420 QEK-APSKKPVKRRKKKRAA 438
+P KK K RK+KR A
Sbjct: 907 DGPISPKKKKPKERKQKRLA 926
>gi|168229156 NFKB activating protein [Homo sapiens]
Length = 415
Score = 30.8 bits (68), Expect = 2.5
Identities = 26/103 (25%), Positives = 40/103 (38%), Gaps = 23/103 (22%)
Query: 342 GVENSWGDLEDSEKEDDEGGGDQAIILDGIKMDTGVEVSDIGSQDAPIILS--------D 393
G + W L D E+E+ ++ E IG AP + D
Sbjct: 109 GSDKPWPSLLDKEREES------------LRQKRLSERERIGELGAPEVWGLSPKNPEPD 156
Query: 394 SEEEEMIILEPDKNPKKIRTQTTSAKQEKAPSKKPVKRRKKKR 436
S+E + D+ PKK T +++++EK K R KKR
Sbjct: 157 SDEHTPV---EDEEPKKSTTSASTSEEEKKKKSSRSKERSKKR 196
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 30.8 bits (68), Expect = 2.5
Identities = 29/139 (20%), Positives = 65/139 (46%), Gaps = 11/139 (7%)
Query: 298 MEKAPIDTSDVEEKAEE---IIAEAEPPSEVVSTPVLWTPGTAQIGEGVENSWGDLEDSE 354
+ K P ++ ++ K+EE ++ ++E + +V T T ++ E E + ++ E
Sbjct: 426 LPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEK---EAKEEE 482
Query: 355 KEDDEGGGDQAIILDGIKMDTGVEVSDIGSQDAPIILSDSEEEEMIILE---PDKNPKKI 411
+++EGG ++ +G + +T ++ + S +EE E P+K K
Sbjct: 483 GKEEEGGEEEE--AEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKS 540
Query: 412 RTQTTSAKQEKAPSKKPVK 430
+ S ++ K+P+K+ K
Sbjct: 541 PAEVKSPEKAKSPAKEEAK 559
>gi|50727002 pseudouridylate synthase 7 homolog [Homo sapiens]
Length = 661
Score = 30.8 bits (68), Expect = 2.5
Identities = 14/35 (40%), Positives = 21/35 (60%)
Query: 326 VSTPVLWTPGTAQIGEGVENSWGDLEDSEKEDDEG 360
+S V P T G+G +NS LED E+E+++G
Sbjct: 54 ISEDVPRPPDTVSTGKGGKNSEAQLEDEEEEEEDG 88
>gi|16306548 seryl-tRNA synthetase [Homo sapiens]
Length = 514
Score = 30.4 bits (67), Expect = 3.3
Identities = 33/138 (23%), Positives = 59/138 (42%), Gaps = 15/138 (10%)
Query: 250 CSKIAGVKVAEITELILKALENDQKVRKEGGKFG--FAESIANQRITAFKMEKAPIDTSD 307
CSK G K+ + + + +D+ V + F A+++AN +++ K + ID +
Sbjct: 60 CSKTIGEKMKK-----KEPVGDDESVPENVLSFDDLTADALANLKVSQIKKVRLLIDEAI 114
Query: 308 VEEKAEEIIAEAEPPSEVVSTPVLWTPGT-----AQIGEGVENSWGDLEDSEKEDDEGGG 362
++ AE I EAE + L P + VE WGD +K
Sbjct: 115 LKCDAERIKLEAERFENLREIGNLLHPSVPISNDEDVDNKVERIWGDCTVRKKYSHV--- 171
Query: 363 DQAIILDGIKMDTGVEVS 380
D +++DG + + G V+
Sbjct: 172 DLVVMVDGFEGEKGAVVA 189
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.134 0.384
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,669,187
Number of Sequences: 37866
Number of extensions: 749262
Number of successful extensions: 3121
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 60
Number of HSP's that attempted gapping in prelim test: 2988
Number of HSP's gapped (non-prelim): 172
length of query: 439
length of database: 18,247,518
effective HSP length: 105
effective length of query: 334
effective length of database: 14,271,588
effective search space: 4766710392
effective search space used: 4766710392
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.