Guide to the Human Genome
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Search of human proteins with 7710154

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7710154 mitochondrial tryptophanyl tRNA synthetase 2 isoform
1 precursor [Homo sapiens]
         (360 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7710154 mitochondrial tryptophanyl tRNA synthetase 2 isoform ...   705   0.0  
gi|41352700 mitochondrial tryptophanyl tRNA synthetase 2 isoform...   425   e-119
gi|223278379 ribosomal RNA processing 12 homolog isoform 1 [Homo...    34   0.18 
gi|10835197 5-hydroxytryptamine (serotonin) receptor 1F [Homo sa...    32   1.2  
gi|167900452 phospholipase C-like 1 isoform a [Homo sapiens]           31   1.5  
gi|167900450 phospholipase C-like 1 isoform b [Homo sapiens]           31   1.5  
gi|24497609 nucleoporin 62kDa [Homo sapiens]                           30   2.6  
gi|24497607 nucleoporin 62kDa [Homo sapiens]                           30   2.6  
gi|24497605 nucleoporin 62kDa [Homo sapiens]                           30   2.6  
gi|24497603 nucleoporin 62kDa [Homo sapiens]                           30   2.6  
gi|62945417 dystrophia myotonica-containing WD repeat motif prot...    30   2.6  
gi|23397456 IQ motif containing K [Homo sapiens]                       30   2.6  
gi|20149640 dual oxidase 1 precursor [Homo sapiens]                    29   5.7  
gi|28872751 dual oxidase 1 precursor [Homo sapiens]                    29   5.7  
gi|51599156 chromodomain helicase DNA binding protein 4 [Homo sa...    29   5.7  
gi|13124883 HsKin17 protein [Homo sapiens]                             29   5.7  
gi|52630326 chromodomain helicase DNA binding protein 3 isoform ...    29   7.5  
gi|52630322 chromodomain helicase DNA binding protein 3 isoform ...    29   7.5  
gi|158420731 chromodomain helicase DNA binding protein 3 isoform...    29   7.5  
gi|112293277 DnaJ (Hsp40) homolog, subfamily C, member 8 [Homo s...    29   7.5  
gi|48762942 huntingtin interacting protein-1-related [Homo sapiens]    28   9.8  
gi|239750456 PREDICTED: similar to KIAA0655 protein [Homo sapiens]     28   9.8  

>gi|7710154 mitochondrial tryptophanyl tRNA synthetase 2 isoform 1
           precursor [Homo sapiens]
          Length = 360

 Score =  705 bits (1820), Expect = 0.0
 Identities = 360/360 (100%), Positives = 360/360 (100%)

Query: 1   MALHSMRKARERWSFIRALHKGSAAAPALQKDSKKRVFSGIQPTGILHLGNYLGAIESWV 60
           MALHSMRKARERWSFIRALHKGSAAAPALQKDSKKRVFSGIQPTGILHLGNYLGAIESWV
Sbjct: 1   MALHSMRKARERWSFIRALHKGSAAAPALQKDSKKRVFSGIQPTGILHLGNYLGAIESWV 60

Query: 61  RLQDEYDSVLYSIVDLHSITVPQDPAVLRQSILDMTAVLLACGINPEKSILFQQSQVSEH 120
           RLQDEYDSVLYSIVDLHSITVPQDPAVLRQSILDMTAVLLACGINPEKSILFQQSQVSEH
Sbjct: 61  RLQDEYDSVLYSIVDLHSITVPQDPAVLRQSILDMTAVLLACGINPEKSILFQQSQVSEH 120

Query: 121 TQLSWILSCMVRLPRLQHLHQWKAKTTKQKHDGTVGLLTYPVLQAADILLYKSTHVPVGE 180
           TQLSWILSCMVRLPRLQHLHQWKAKTTKQKHDGTVGLLTYPVLQAADILLYKSTHVPVGE
Sbjct: 121 TQLSWILSCMVRLPRLQHLHQWKAKTTKQKHDGTVGLLTYPVLQAADILLYKSTHVPVGE 180

Query: 181 DQVQHMELVQDLAQGFNKKYGEFFPVPESILTSMKKVKSLRDPSAKMSKSDPDKLATVRI 240
           DQVQHMELVQDLAQGFNKKYGEFFPVPESILTSMKKVKSLRDPSAKMSKSDPDKLATVRI
Sbjct: 181 DQVQHMELVQDLAQGFNKKYGEFFPVPESILTSMKKVKSLRDPSAKMSKSDPDKLATVRI 240

Query: 241 TDSPEEIVQKFRKAVTDFTSEVTYDPAGRAGVSNIVAVHAAVTGLSVEEVVRRSAGMNTA 300
           TDSPEEIVQKFRKAVTDFTSEVTYDPAGRAGVSNIVAVHAAVTGLSVEEVVRRSAGMNTA
Sbjct: 241 TDSPEEIVQKFRKAVTDFTSEVTYDPAGRAGVSNIVAVHAAVTGLSVEEVVRRSAGMNTA 300

Query: 301 RYKLAVADAVIEKFAPIKREIEKLKLDKDHLEKVLQIGSAKAKELAYTVCQEVKKLVGFL 360
           RYKLAVADAVIEKFAPIKREIEKLKLDKDHLEKVLQIGSAKAKELAYTVCQEVKKLVGFL
Sbjct: 301 RYKLAVADAVIEKFAPIKREIEKLKLDKDHLEKVLQIGSAKAKELAYTVCQEVKKLVGFL 360


>gi|41352700 mitochondrial tryptophanyl tRNA synthetase 2 isoform 2
           precursor [Homo sapiens]
          Length = 220

 Score =  425 bits (1093), Expect = e-119
 Identities = 211/212 (99%), Positives = 212/212 (100%)

Query: 1   MALHSMRKARERWSFIRALHKGSAAAPALQKDSKKRVFSGIQPTGILHLGNYLGAIESWV 60
           MALHSMRKARERWSFIRALHKGSAAAPALQKDSKKRVFSGIQPTGILHLGNYLGAIESWV
Sbjct: 1   MALHSMRKARERWSFIRALHKGSAAAPALQKDSKKRVFSGIQPTGILHLGNYLGAIESWV 60

Query: 61  RLQDEYDSVLYSIVDLHSITVPQDPAVLRQSILDMTAVLLACGINPEKSILFQQSQVSEH 120
           RLQDEYDSVLYSIVDLHSITVPQDPAVLRQSILDMTAVLLACGINPEKSILFQQSQVSEH
Sbjct: 61  RLQDEYDSVLYSIVDLHSITVPQDPAVLRQSILDMTAVLLACGINPEKSILFQQSQVSEH 120

Query: 121 TQLSWILSCMVRLPRLQHLHQWKAKTTKQKHDGTVGLLTYPVLQAADILLYKSTHVPVGE 180
           TQLSWILSCMVRLPRLQHLHQWKAKTTKQKHDGTVGLLTYPVLQAADILLYKSTHVPVGE
Sbjct: 121 TQLSWILSCMVRLPRLQHLHQWKAKTTKQKHDGTVGLLTYPVLQAADILLYKSTHVPVGE 180

Query: 181 DQVQHMELVQDLAQGFNKKYGEFFPVPESILT 212
           DQVQHMELVQDLAQGFNKKYGEFFPVPESIL+
Sbjct: 181 DQVQHMELVQDLAQGFNKKYGEFFPVPESILS 212


>gi|223278379 ribosomal RNA processing 12 homolog isoform 1 [Homo
           sapiens]
          Length = 1297

 Score = 34.3 bits (77), Expect = 0.18
 Identities = 16/52 (30%), Positives = 24/52 (46%)

Query: 110 ILFQQSQVSEHTQLSWILSCMVRLPRLQHLHQWKAKTTKQKHDGTVGLLTYP 161
           I+  Q+     + L W+LSC+  L R Q L  W    T Q + G +    +P
Sbjct: 197 IMSAQASSGSTSVLRWVLSCLATLLRKQDLEAWGYPVTLQVYHGLLSFTVHP 248


>gi|10835197 5-hydroxytryptamine (serotonin) receptor 1F [Homo
           sapiens]
          Length = 366

 Score = 31.6 bits (70), Expect = 1.2
 Identities = 54/229 (23%), Positives = 93/229 (40%), Gaps = 51/229 (22%)

Query: 57  ESWVRLQDEYDSVLYSIVDLHSITVPQDPAVLRQSILDMTAVLLACGINPEKSILFQQSQ 116
           ESW+  Q   D  ++  VD+   T          SIL ++A+ L        ++ + + +
Sbjct: 87  ESWIMGQVVCD--IWLSVDITCCTC---------SILHLSAIALDRYRAITDAVEYARKR 135

Query: 117 VSEHTQLS----WILSCMVRLPRLQHLHQWKAKTTKQ--KHDGTVG-------------- 156
             +H  +     WI+S  + +P L   HQ  ++  +   KHD  V               
Sbjct: 136 TPKHAGIMITIVWIISVFISMPPLFWRHQGTSRDDECIIKHDHIVSTIYSTFGAFYIPLA 195

Query: 157 ---LLTYPVLQAADILLYKSTHVPVGEDQVQHMELVQDLAQGFNKKYGEFFPVPESILTS 213
              +L Y + +AA  L +K     + +++V    L++          GE     +S+ TS
Sbjct: 196 LILILYYKIYRAAKTLYHKRQASRIAKEEVNGQVLLES---------GE--KSTKSVSTS 244

Query: 214 MKKVKSLRDPSAKMSKSDPDKL-ATVRITDSPEEIVQKFRKAVTDFTSE 261
               KSL DPS     +D DK+ +TVR   S  +  + +R+     T E
Sbjct: 245 YVLEKSLSDPS-----TDFDKIHSTVRSLRSEFKHEKSWRRQKISGTRE 288


>gi|167900452 phospholipase C-like 1 isoform a [Homo sapiens]
          Length = 1095

 Score = 31.2 bits (69), Expect = 1.5
 Identities = 25/79 (31%), Positives = 36/79 (45%), Gaps = 3/79 (3%)

Query: 184 QHMELVQDLAQGFNKKYGEFFPVP-ESILTSMKKVKSLRDPSAKMSKSDPDKLATVRITD 242
           Q   + Q + + F  K     P+P ES L S +K+K +     K   SDPD L    +TD
Sbjct: 499 QQKVMAQQMKKVFGNKLYTEAPLPSESYLPSPEKLKRMIIVKGKKLPSDPDVLEG-EVTD 557

Query: 243 SPEEIVQKFRKAVTDFTSE 261
             EE  +  R+   D+  E
Sbjct: 558 EDEE-AEMSRRMSVDYNGE 575


>gi|167900450 phospholipase C-like 1 isoform b [Homo sapiens]
          Length = 997

 Score = 31.2 bits (69), Expect = 1.5
 Identities = 25/79 (31%), Positives = 36/79 (45%), Gaps = 3/79 (3%)

Query: 184 QHMELVQDLAQGFNKKYGEFFPVP-ESILTSMKKVKSLRDPSAKMSKSDPDKLATVRITD 242
           Q   + Q + + F  K     P+P ES L S +K+K +     K   SDPD L    +TD
Sbjct: 401 QQKVMAQQMKKVFGNKLYTEAPLPSESYLPSPEKLKRMIIVKGKKLPSDPDVLEG-EVTD 459

Query: 243 SPEEIVQKFRKAVTDFTSE 261
             EE  +  R+   D+  E
Sbjct: 460 EDEE-AEMSRRMSVDYNGE 477


>gi|24497609 nucleoporin 62kDa [Homo sapiens]
          Length = 522

 Score = 30.4 bits (67), Expect = 2.6
 Identities = 14/34 (41%), Positives = 22/34 (64%)

Query: 312 EKFAPIKREIEKLKLDKDHLEKVLQIGSAKAKEL 345
           EK   + RE+EK+KLD+  L++ L    ++ KEL
Sbjct: 370 EKITSLHREVEKVKLDQKRLDQELDFILSQQKEL 403


>gi|24497607 nucleoporin 62kDa [Homo sapiens]
          Length = 522

 Score = 30.4 bits (67), Expect = 2.6
 Identities = 14/34 (41%), Positives = 22/34 (64%)

Query: 312 EKFAPIKREIEKLKLDKDHLEKVLQIGSAKAKEL 345
           EK   + RE+EK+KLD+  L++ L    ++ KEL
Sbjct: 370 EKITSLHREVEKVKLDQKRLDQELDFILSQQKEL 403


>gi|24497605 nucleoporin 62kDa [Homo sapiens]
          Length = 522

 Score = 30.4 bits (67), Expect = 2.6
 Identities = 14/34 (41%), Positives = 22/34 (64%)

Query: 312 EKFAPIKREIEKLKLDKDHLEKVLQIGSAKAKEL 345
           EK   + RE+EK+KLD+  L++ L    ++ KEL
Sbjct: 370 EKITSLHREVEKVKLDQKRLDQELDFILSQQKEL 403


>gi|24497603 nucleoporin 62kDa [Homo sapiens]
          Length = 522

 Score = 30.4 bits (67), Expect = 2.6
 Identities = 14/34 (41%), Positives = 22/34 (64%)

Query: 312 EKFAPIKREIEKLKLDKDHLEKVLQIGSAKAKEL 345
           EK   + RE+EK+KLD+  L++ L    ++ KEL
Sbjct: 370 EKITSLHREVEKVKLDQKRLDQELDFILSQQKEL 403


>gi|62945417 dystrophia myotonica-containing WD repeat motif protein
           [Homo sapiens]
          Length = 674

 Score = 30.4 bits (67), Expect = 2.6
 Identities = 31/116 (26%), Positives = 48/116 (41%), Gaps = 9/116 (7%)

Query: 10  RERWSFIRALHKGSAAAPALQKDSKKRVFSGIQPTGILHLGNYLGAIESWVRLQDEYDSV 69
           RE + +     +GS  +  L K   KR++ G QPT   H  N   A    + L   + + 
Sbjct: 132 RELYFYPGCCRRGSQRSIDLNKPIDKRIYKGTQPT--CHDFNQFTAATETISLLVGFSAG 189

Query: 70  LYSIVDLHSITVPQDPAVL--RQSILDMTAVLLACGINPEKSILFQQSQVSEHTQL 123
               +DL    + +D + L   + ++D T V     + PE   LF  S  S H  L
Sbjct: 190 QVQYLDL----IKKDTSKLFNEERLIDKTKVTYLKWL-PESESLFLASHASGHLYL 240


>gi|23397456 IQ motif containing K [Homo sapiens]
          Length = 287

 Score = 30.4 bits (67), Expect = 2.6
 Identities = 15/44 (34%), Positives = 25/44 (56%), Gaps = 2/44 (4%)

Query: 109 SILFQQSQVSEHTQLSWILSCMVRL-PRLQHLHQWKAKTTKQKH 151
           S+L  + + + + Q  W  +C+VR  P +Q L QW+ K  + KH
Sbjct: 210 SLLLTEEEAALYIQSFW-RACVVRCDPEIQELRQWQKKLREAKH 252


>gi|20149640 dual oxidase 1 precursor [Homo sapiens]
          Length = 1551

 Score = 29.3 bits (64), Expect = 5.7
 Identities = 17/41 (41%), Positives = 23/41 (56%), Gaps = 6/41 (14%)

Query: 224  SAKMSKSD------PDKLATVRITDSPEEIVQKFRKAVTDF 258
            SA+ S+SD      P +L     TD P+EI ++F K VT F
Sbjct: 969  SARCSRSDIETELTPQRLQCPMDTDPPQEIRRRFGKKVTSF 1009


>gi|28872751 dual oxidase 1 precursor [Homo sapiens]
          Length = 1551

 Score = 29.3 bits (64), Expect = 5.7
 Identities = 17/41 (41%), Positives = 23/41 (56%), Gaps = 6/41 (14%)

Query: 224  SAKMSKSD------PDKLATVRITDSPEEIVQKFRKAVTDF 258
            SA+ S+SD      P +L     TD P+EI ++F K VT F
Sbjct: 969  SARCSRSDIETELTPQRLQCPMDTDPPQEIRRRFGKKVTSF 1009


>gi|51599156 chromodomain helicase DNA binding protein 4 [Homo
            sapiens]
          Length = 1912

 Score = 29.3 bits (64), Expect = 5.7
 Identities = 20/73 (27%), Positives = 38/73 (52%), Gaps = 4/73 (5%)

Query: 285  LSVEEVVRRSAGMNTARYKLAVADAVIEKFAPIKREIEKLKLDKDHLEKVLQIGSAKAKE 344
            L +EE +RR+A +N +      + A+  +FA    E+E L     HL K    G+  A  
Sbjct: 1793 LVIEEQLRRAAYLNMSEDPSHPSMALNTRFA----EVECLAESHQHLSKESMAGNKPANA 1848

Query: 345  LAYTVCQEVKKLV 357
            + + V +++++L+
Sbjct: 1849 VLHKVLKQLEELL 1861


>gi|13124883 HsKin17 protein [Homo sapiens]
          Length = 393

 Score = 29.3 bits (64), Expect = 5.7
 Identities = 15/36 (41%), Positives = 23/36 (63%), Gaps = 3/36 (8%)

Query: 303 KLAVADAVIEKFAPIKREIE---KLKLDKDHLEKVL 335
           K A+   VI+K+  + + I+   KLKLD+ HLE V+
Sbjct: 301 KKAIVKEVIDKYTAVVKMIDSGDKLKLDQTHLETVI 336


>gi|52630326 chromodomain helicase DNA binding protein 3 isoform 1
            [Homo sapiens]
          Length = 2000

 Score = 28.9 bits (63), Expect = 7.5
 Identities = 21/73 (28%), Positives = 37/73 (50%), Gaps = 4/73 (5%)

Query: 285  LSVEEVVRRSAGMNTARYKLAVADAVIEKFAPIKREIEKLKLDKDHLEKVLQIGSAKAKE 344
            L +EE +RR+A +N ++     A A+  +FA    E E L     HL K    G+  A  
Sbjct: 1804 LVIEEQLRRAAYLNLSQEPAHPAMALHARFA----EAECLAESHQHLSKESLAGNKPANA 1859

Query: 345  LAYTVCQEVKKLV 357
            + + V  ++++L+
Sbjct: 1860 VLHKVLNQLEELL 1872


>gi|52630322 chromodomain helicase DNA binding protein 3 isoform 2
            [Homo sapiens]
          Length = 1966

 Score = 28.9 bits (63), Expect = 7.5
 Identities = 21/73 (28%), Positives = 37/73 (50%), Gaps = 4/73 (5%)

Query: 285  LSVEEVVRRSAGMNTARYKLAVADAVIEKFAPIKREIEKLKLDKDHLEKVLQIGSAKAKE 344
            L +EE +RR+A +N ++     A A+  +FA    E E L     HL K    G+  A  
Sbjct: 1770 LVIEEQLRRAAYLNLSQEPAHPAMALHARFA----EAECLAESHQHLSKESLAGNKPANA 1825

Query: 345  LAYTVCQEVKKLV 357
            + + V  ++++L+
Sbjct: 1826 VLHKVLNQLEELL 1838


>gi|158420731 chromodomain helicase DNA binding protein 3 isoform 3
            [Homo sapiens]
          Length = 2059

 Score = 28.9 bits (63), Expect = 7.5
 Identities = 21/73 (28%), Positives = 37/73 (50%), Gaps = 4/73 (5%)

Query: 285  LSVEEVVRRSAGMNTARYKLAVADAVIEKFAPIKREIEKLKLDKDHLEKVLQIGSAKAKE 344
            L +EE +RR+A +N ++     A A+  +FA    E E L     HL K    G+  A  
Sbjct: 1863 LVIEEQLRRAAYLNLSQEPAHPAMALHARFA----EAECLAESHQHLSKESLAGNKPANA 1918

Query: 345  LAYTVCQEVKKLV 357
            + + V  ++++L+
Sbjct: 1919 VLHKVLNQLEELL 1931


>gi|112293277 DnaJ (Hsp40) homolog, subfamily C, member 8 [Homo
           sapiens]
          Length = 253

 Score = 28.9 bits (63), Expect = 7.5
 Identities = 31/125 (24%), Positives = 58/125 (46%), Gaps = 2/125 (1%)

Query: 208 ESILTSMKKVKSLRDPSAKMSKSDPDKLATVRITDSPEEIVQKFRKAVTDFTSEVTYDPA 267
           +S+LTS  +++ L  P +     +P ++  +    + EEI ++FR+       +   D A
Sbjct: 34  DSVLTSKNQIERLTRPGSSYFNLNPFEVLQIDPEVTDEEIKKRFRQLSILVHPDKNQDDA 93

Query: 268 GRAGVSNIVAVHAAVTGLSVEEVVRRSAGMNTARYKLAVADAVIEKFAPIKREIEKLKLD 327
            RA  +   AV  A   L  +E  +R+  +  A  K  V   V E+   +K+E +   ++
Sbjct: 94  DRAQKA-FEAVDKAYKLLLDQEQKKRALDVIQAG-KEYVEHTVKERKKQLKKEGKPTIVE 151

Query: 328 KDHLE 332
           +D  E
Sbjct: 152 EDDPE 156


>gi|48762942 huntingtin interacting protein-1-related [Homo sapiens]
          Length = 1068

 Score = 28.5 bits (62), Expect = 9.8
 Identities = 22/75 (29%), Positives = 36/75 (48%), Gaps = 1/75 (1%)

Query: 273 SNIVAVHAAVTGLSVEEVVRRSAGMNTARYKLAVADAVIEKFAPIKREIE-KLKLDKDHL 331
           S +V VHA +   + +   + +    +      V + +  +   +KRE E KL+   D L
Sbjct: 455 SELVHVHAELLRKNADTAKQLTVTQQSQEEVARVKEQLAFQVEQVKRESELKLEEKSDQL 514

Query: 332 EKVLQIGSAKAKELA 346
           EK+ +   AKA ELA
Sbjct: 515 EKLKRELEAKAGELA 529


>gi|239750456 PREDICTED: similar to KIAA0655 protein [Homo sapiens]
          Length = 1048

 Score = 28.5 bits (62), Expect = 9.8
 Identities = 22/75 (29%), Positives = 36/75 (48%), Gaps = 1/75 (1%)

Query: 273 SNIVAVHAAVTGLSVEEVVRRSAGMNTARYKLAVADAVIEKFAPIKREIE-KLKLDKDHL 331
           S +V VHA +   + +   + +    +      V + +  +   +KRE E KL+   D L
Sbjct: 435 SELVHVHAELLRKNADTAKQLTVTQQSQEEVARVKEQLAFQVEQVKRESELKLEEKSDQL 494

Query: 332 EKVLQIGSAKAKELA 346
           EK+ +   AKA ELA
Sbjct: 495 EKLKRELEAKAGELA 509


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.132    0.374 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,659,358
Number of Sequences: 37866
Number of extensions: 528585
Number of successful extensions: 1572
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 1562
Number of HSP's gapped (non-prelim): 25
length of query: 360
length of database: 18,247,518
effective HSP length: 103
effective length of query: 257
effective length of database: 14,347,320
effective search space: 3687261240
effective search space used: 3687261240
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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