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Search of human proteins with 7706687
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7706687 Enah/Vasp-like [Homo sapiens]
(418 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7706687 Enah/Vasp-like [Homo sapiens] 834 0.0
gi|4507869 vasodilator-stimulated phosphoprotein [Homo sapiens] 314 1e-85
gi|56549694 enabled homolog isoform a [Homo sapiens] 210 2e-54
gi|39930375 enabled homolog isoform b [Homo sapiens] 210 2e-54
gi|110225353 sprouty-related, EVH1 domain containing 3 isoform a... 79 6e-15
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap... 74 3e-13
gi|22749221 sprouty-related protein 1 with EVH-1 domain [Homo sa... 69 8e-12
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 67 4e-11
gi|189571671 sprouty-related protein with EVH-1 domain 2 isoform... 63 4e-10
gi|88853871 sprouty-related, EVH1 domain containing 3 isoform b ... 63 4e-10
gi|189571669 sprouty-related protein with EVH-1 domain 2 isoform... 62 1e-09
gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens] 61 2e-09
gi|32698936 B-cell CLL/lymphoma 9-like [Homo sapiens] 61 2e-09
gi|47132519 Ras association and pleckstrin homology domains 1 is... 60 3e-09
gi|150378503 leiomodin 2 (cardiac) [Homo sapiens] 59 8e-09
gi|7657387 CCR4-NOT transcription complex, subunit 3 [Homo sapiens] 59 8e-09
gi|110431370 espin [Homo sapiens] 59 1e-08
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 58 1e-08
gi|52485606 formin-like 2 [Homo sapiens] 58 2e-08
gi|158854042 hypothetical protein LOC222183 [Homo sapiens] 58 2e-08
gi|4557329 fas ligand [Homo sapiens] 57 3e-08
gi|150170670 piccolo isoform 2 [Homo sapiens] 57 4e-08
gi|150378539 piccolo isoform 1 [Homo sapiens] 57 4e-08
gi|82546824 forkhead box K1 [Homo sapiens] 57 4e-08
gi|157168329 formin 1 [Homo sapiens] 56 7e-08
gi|39812378 RAN binding protein 9 [Homo sapiens] 56 7e-08
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap... 56 7e-08
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 55 9e-08
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 55 9e-08
gi|126090663 zinc finger homeodomain 4 [Homo sapiens] 55 9e-08
>gi|7706687 Enah/Vasp-like [Homo sapiens]
Length = 418
Score = 834 bits (2155), Expect = 0.0
Identities = 418/418 (100%), Positives = 418/418 (100%)
Query: 1 MATSEQSICQARASVMVYDDTSKKWVPIKPGQQGFSRINIYHNTASNTFRVVGVKLQDQQ 60
MATSEQSICQARASVMVYDDTSKKWVPIKPGQQGFSRINIYHNTASNTFRVVGVKLQDQQ
Sbjct: 1 MATSEQSICQARASVMVYDDTSKKWVPIKPGQQGFSRINIYHNTASNTFRVVGVKLQDQQ 60
Query: 61 VVINYSIVKGLKYNQATPTFHQWRDARQVYGLNFASKEEATTFSNAMLFALNIMNSQEGG 120
VVINYSIVKGLKYNQATPTFHQWRDARQVYGLNFASKEEATTFSNAMLFALNIMNSQEGG
Sbjct: 61 VVINYSIVKGLKYNQATPTFHQWRDARQVYGLNFASKEEATTFSNAMLFALNIMNSQEGG 120
Query: 121 PSSQRQVQNGPSPDEMDIQRRQVMEQHQQQRQESLERRTSATGPILPPGHPSSAASAPVS 180
PSSQRQVQNGPSPDEMDIQRRQVMEQHQQQRQESLERRTSATGPILPPGHPSSAASAPVS
Sbjct: 121 PSSQRQVQNGPSPDEMDIQRRQVMEQHQQQRQESLERRTSATGPILPPGHPSSAASAPVS 180
Query: 181 CSGPPPPPPPPVPPPPTGATPPPPPPLPAGGAQGSSHDESSMSGLAAAIAGAKLRRVQRP 240
CSGPPPPPPPPVPPPPTGATPPPPPPLPAGGAQGSSHDESSMSGLAAAIAGAKLRRVQRP
Sbjct: 181 CSGPPPPPPPPVPPPPTGATPPPPPPLPAGGAQGSSHDESSMSGLAAAIAGAKLRRVQRP 240
Query: 241 EDASGGSSPSGTSKSDANRASSGGGGGGLMEEMNKLLAKRRKAASQSDKPAEKKEDESQM 300
EDASGGSSPSGTSKSDANRASSGGGGGGLMEEMNKLLAKRRKAASQSDKPAEKKEDESQM
Sbjct: 241 EDASGGSSPSGTSKSDANRASSGGGGGGLMEEMNKLLAKRRKAASQSDKPAEKKEDESQM 300
Query: 301 EDPSTSPSPGTRAASQPPNSSEAGRKPWERSNSVEKPVSSILSRTPSVAKSPEAKSPLQS 360
EDPSTSPSPGTRAASQPPNSSEAGRKPWERSNSVEKPVSSILSRTPSVAKSPEAKSPLQS
Sbjct: 301 EDPSTSPSPGTRAASQPPNSSEAGRKPWERSNSVEKPVSSILSRTPSVAKSPEAKSPLQS 360
Query: 361 QPHSRMKPAGSVNDMALDAFDLDRMKQEILEEVVRELHKVKEEIIDAIRQELSGISTT 418
QPHSRMKPAGSVNDMALDAFDLDRMKQEILEEVVRELHKVKEEIIDAIRQELSGISTT
Sbjct: 361 QPHSRMKPAGSVNDMALDAFDLDRMKQEILEEVVRELHKVKEEIIDAIRQELSGISTT 418
>gi|4507869 vasodilator-stimulated phosphoprotein [Homo sapiens]
Length = 380
Score = 314 bits (804), Expect = 1e-85
Identities = 199/427 (46%), Positives = 253/427 (59%), Gaps = 72/427 (16%)
Query: 4 SEQSICQARASVMVYDDTSKKWVPIKPGQQGFSRINIYHNTASNTFRVVGVKLQ-DQQVV 62
SE IC +RA+VM+YDD +K+W+P G Q FSR+ IYHN +N+FRVVG K+Q DQQVV
Sbjct: 2 SETVICSSRATVMLYDDGNKRWLPAGTGPQAFSRVQIYHNPTANSFRVVGRKMQPDQQVV 61
Query: 63 INYSIVKGLKYNQATPTFHQWRDARQVYGLNFASKEEATTFSNAMLFALNIMNSQEGGPS 122
IN +IV+G+KYNQATP FHQWRDARQV+GLNF SKE+A F+ M AL + + GGP
Sbjct: 62 INCAIVRGVKYNQATPNFHQWRDARQVWGLNFGSKEDAAQFAAGMASALEAL--EGGGPP 119
Query: 123 SQR-----QVQNGPSPDEMDIQRRQVMEQHQQQRQESLERRTSATGPILPPGHPSSAASA 177
V NGPSP+E++ Q+RQ Q E +ERR S G G P+ A
Sbjct: 120 PPPALPTWSVPNGPSPEEVEQQKRQ-----QPGPSEHIERRVSNAG-----GPPAPPAGG 169
Query: 178 PVSCSGPPPPPPPPVPP--PPTGAT---------PPPPPPLPAGGAQGSSHDESSMSGLA 226
P GPPPPP PP PP PP+G PPP PPLPA AQG + GLA
Sbjct: 170 PPPPPGPPPPPGPPPPPGLPPSGVPAAAHGAGGGPPPAPPLPA--AQGPGGGGAGAPGLA 227
Query: 227 AAIAGAKLRRVQRPEDASGGSSPSGTSKSDANRASSG-GGGGGLMEEMNKLLAKRRKAAS 285
AAIAGAKLR+V + E+ASGG + A +A SG GGGGLMEEMN +LA+RRKA
Sbjct: 228 AAIAGAKLRKVSKQEEASGGPT--------APKAESGRSGGGGLMEEMNAMLARRRKATQ 279
Query: 286 QSDKPAEKKEDESQMEDPSTSPSPGTRAASQPPNSSEAGRKPWERSNSVEKPVSSILSRT 345
+K K++ + E+P ++ P SE+ R+PWE++++ + S S T
Sbjct: 280 VGEK--TPKDESANQEEPE----------ARVPAQSESVRRPWEKNSTTLPRMKSSSSVT 327
Query: 346 PSVAKSPEAKSPLQSQPHSRMKPAGSVNDMALDAFDLDRMKQEILEEVVRELHKVKEEII 405
S ++QP P+ S D DL R+KQE+LEEV +EL KVKEEII
Sbjct: 328 TS-----------ETQP---CTPSSS------DYSDLQRVKQELLEEVKKELQKVKEEII 367
Query: 406 DAIRQEL 412
+A QEL
Sbjct: 368 EAFVQEL 374
>gi|56549694 enabled homolog isoform a [Homo sapiens]
Length = 591
Score = 210 bits (535), Expect = 2e-54
Identities = 108/161 (67%), Positives = 128/161 (79%), Gaps = 11/161 (6%)
Query: 4 SEQSICQARASVMVYDDTSKKWVPIKPGQQGFSRINIYHNTASNTFRVVGVKLQDQQVVI 63
SEQSICQARA+VMVYDD +KKWVP G GFSR++IYH+T +NTFRVVG K+QD QVVI
Sbjct: 2 SEQSICQARAAVMVYDDANKKWVPAG-GSTGFSRVHIYHHTGNNTFRVVGRKIQDHQVVI 60
Query: 64 NYSIVKGLKYNQATPTFHQWRDARQVYGLNFASKEEATTFSNAMLFALNIMNSQEGGPSS 123
N +I KGLKYNQAT TFHQWRDARQVYGLNF SKE+A F++AM+ AL ++NSQE GP+
Sbjct: 61 NCAIPKGLKYNQATQTFHQWRDARQVYGLNFGSKEDANVFASAMMHALEVLNSQETGPTL 120
Query: 124 QR-------QVQNGPSPDEMDIQRRQVMEQHQQQRQESLER 157
R QVQNGPS +E++IQRRQ+ E QQRQ+ LER
Sbjct: 121 PRQNSQLPAQVQNGPSQEELEIQRRQLQE---QQRQKELER 158
Score = 179 bits (454), Expect = 4e-45
Identities = 122/285 (42%), Positives = 162/285 (56%), Gaps = 42/285 (14%)
Query: 164 PILPPGHPSSAASA-----------PVSCSGPPPPPPPP-----VPPPPTGATPPPPPPL 207
P LPPG P+ A+ A P+ +GPPPPPPPP VPPPP PPP PPL
Sbjct: 317 PPLPPG-PAQASVALPPPPGPPPPPPLPSTGPPPPPPPPPLPNQVPPPPP---PPPAPPL 372
Query: 208 PAGG--AQGSSHDESSMSGLAAAIAGAKLRRVQRPEDA---SGGSS---PSGTSKSDANR 259
PA G S D ++GLAAAIAGAKLR+V R ED SGG++ S +SK+D R
Sbjct: 373 PASGFFLASMSEDNRPLTGLAAAIAGAKLRKVSRMEDTSFPSGGNAIGVNSASSKTDTGR 432
Query: 260 ASS--GGGGGGLMEEMNKLLAKRRKAASQ-SDKPAEKKEDESQMEDPSTSPSPGTRAASQ 316
+ GG GLMEEM+ LLA+RR+ A + S E+KED+ + +P TS + T
Sbjct: 433 GNGPLPLGGSGLMEEMSALLARRRRIAEKGSTIETEQKEDKGEDSEPVTSKASST----- 487
Query: 317 PPNSSEAGRKPWERSNSVEKPVSSILSRTPSVAKS----PEAKSPLQSQPHSRMKPAGSV 372
++ E RKPWER+N++ S ++SR S K+ +P S S
Sbjct: 488 --STPEPTRKPWERTNTMNGSKSPVISRRDSPRKNQIVFDNRSYDSLHRPKSTPLSQPSA 545
Query: 373 NDMALDAFDLDRMKQEILEEVVRELHKVKEEIIDAIRQELSGIST 417
N + + D DR+KQ+IL+E+ +EL K+KEE+IDAIRQELS +T
Sbjct: 546 NGVQTEGLDYDRLKQDILDEMRKELTKLKEELIDAIRQELSKSNT 590
Score = 33.5 bits (75), Expect = 0.37
Identities = 34/118 (28%), Positives = 45/118 (38%), Gaps = 16/118 (13%)
Query: 114 MNSQEGGPSSQRQVQNGPSPDEMDIQRRQVMEQHQQQRQESLERR----------TSATG 163
+ QE +R + E + R E+ +++RQE LER +SA
Sbjct: 210 LERQERLERQERLDRERQERQERERLERLERERQERERQEQLEREQLEWERERRISSAAA 269
Query: 164 PI-----LPPGHPSSAASAPVSCSGPPPPPPPPVPPPPTGATP-PPPPPLPAGGAQGS 215
P L S+AS P + P P G PPPPPLP G AQ S
Sbjct: 270 PASVETPLNSVLGDSSASEPGLQAASQPAETPSQQGIVLGPLAPPPPPPLPPGPAQAS 327
>gi|39930375 enabled homolog isoform b [Homo sapiens]
Length = 570
Score = 210 bits (535), Expect = 2e-54
Identities = 108/161 (67%), Positives = 128/161 (79%), Gaps = 11/161 (6%)
Query: 4 SEQSICQARASVMVYDDTSKKWVPIKPGQQGFSRINIYHNTASNTFRVVGVKLQDQQVVI 63
SEQSICQARA+VMVYDD +KKWVP G GFSR++IYH+T +NTFRVVG K+QD QVVI
Sbjct: 2 SEQSICQARAAVMVYDDANKKWVPAG-GSTGFSRVHIYHHTGNNTFRVVGRKIQDHQVVI 60
Query: 64 NYSIVKGLKYNQATPTFHQWRDARQVYGLNFASKEEATTFSNAMLFALNIMNSQEGGPSS 123
N +I KGLKYNQAT TFHQWRDARQVYGLNF SKE+A F++AM+ AL ++NSQE GP+
Sbjct: 61 NCAIPKGLKYNQATQTFHQWRDARQVYGLNFGSKEDANVFASAMMHALEVLNSQETGPTL 120
Query: 124 QR-------QVQNGPSPDEMDIQRRQVMEQHQQQRQESLER 157
R QVQNGPS +E++IQRRQ+ E QQRQ+ LER
Sbjct: 121 PRQNSQLPAQVQNGPSQEELEIQRRQLQE---QQRQKELER 158
Score = 178 bits (452), Expect = 7e-45
Identities = 124/281 (44%), Positives = 163/281 (58%), Gaps = 55/281 (19%)
Query: 164 PILPPGHPSSAASA-----------PVSCSGPPPPPPPP-----VPPPPTGATPPPPPPL 207
P LPPG P+ A+ A P+ +GPPPPPPPP VPPPP PPP PPL
Sbjct: 317 PPLPPG-PAQASVALPPPPGPPPPPPLPSTGPPPPPPPPPLPNQVPPPPP---PPPAPPL 372
Query: 208 PAGG--AQGSSHDESSMSGLAAAIAGAKLRRVQRPEDA---SGGSS---PSGTSKSDANR 259
PA G S D ++GLAAAIAGAKLR+V R ED SGG++ S +SK+D R
Sbjct: 373 PASGFFLASMSEDNRPLTGLAAAIAGAKLRKVSRMEDTSFPSGGNAIGVNSASSKTDTGR 432
Query: 260 ASS--GGGGGGLMEEMNKLLAKRRKAASQ-SDKPAEKKEDESQMEDPSTSPSPGTRAASQ 316
+ GG GLMEEM+ LLA+RR+ A + S E+KED+ + +P TS + T
Sbjct: 433 GNGPLPLGGSGLMEEMSALLARRRRIAEKGSTIETEQKEDKGEDSEPVTSKASST----- 487
Query: 317 PPNSSEAGRKPWERSNSVEKPVSSILSRTPSVAKSPEAKSPLQSQPHSRMKPAGSVNDMA 376
++ E RKPWER+N++ S ++SR S +PL SQP S N +
Sbjct: 488 --STPEPTRKPWERTNTMNGSKSPVISRPKS--------TPL-SQP--------SANGVQ 528
Query: 377 LDAFDLDRMKQEILEEVVRELHKVKEEIIDAIRQELSGIST 417
+ D DR+KQ+IL+E+ +EL K+KEE+IDAIRQELS +T
Sbjct: 529 TEGLDYDRLKQDILDEMRKELTKLKEELIDAIRQELSKSNT 569
>gi|110225353 sprouty-related, EVH1 domain containing 3 isoform a
[Homo sapiens]
Length = 410
Score = 79.3 bits (194), Expect = 6e-15
Identities = 85/328 (25%), Positives = 122/328 (37%), Gaps = 46/328 (14%)
Query: 10 QARASVMVYDDTSKKWVPIKPGQQGFSRINIYH--------NTASNTFRVVGVKLQDQQV 61
+ RA VM DD+S W+P+ G G S++++ + + G +L+DQ+
Sbjct: 3 RVRAVVMARDDSSGGWLPVGGG--GLSQVSVCRVRGARPEGGARQGHYVIHGERLRDQKT 60
Query: 62 VINYSIVKGLKYNQATPTFHQWRDARQVYGLNFASKEEATTFSNAMLFALNIMNSQEGGP 121
+ ++ GL YN+ P FH W +GL F S EA F ++L AL + P
Sbjct: 61 TLECTLKPGLVYNKVNPIFHHWSLGDCKFGLTFQSPAEADEFQKSLLAALAALGRGSLTP 120
Query: 122 SSQRQVQNGPSPDEMDIQRRQVMEQHQQQRQESLERRTSATGPILPPGHPSSAASAPV-- 179
SS + SP + + + H S R P SAA+AP+
Sbjct: 121 SSS---SSSSSPSQDTAETPCPLTSHVDSDSSSSHSRQET---------PPSAAAAPIIT 168
Query: 180 --SCSGPPPPPPPPVPPPPTGATPPPPPPLPAGGAQGSSHDESSMSGLAAAIAGAKLRRV 237
S SG P P P + PP LP G S + GL G + R
Sbjct: 169 MESASGFGPTTP---PQRRRSSAQSYPPLLPFTGIPEPSEPLAGAGGLGWGGRGYEDYR- 224
Query: 238 QRPEDASGGSSPSGTSKSDANRASSGGGGGGLMEEMNKLLAKRRKAASQSDKPAEKKEDE 297
SG +P S A +G G + L A +AA + PA
Sbjct: 225 -----RSGPPAPLALSTCVVRFAKTGALRGAALGPPAALPAPLTEAAPPA-PPAR----- 273
Query: 298 SQMEDPSTSPSPGTRAASQPPNSSEAGR 325
P P P + A P + EA R
Sbjct: 274 -----PPPGPGPSSAPAKASPEAEEAAR 296
>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
sapiens]
Length = 505
Score = 73.6 bits (179), Expect = 3e-13
Identities = 60/168 (35%), Positives = 75/168 (44%), Gaps = 44/168 (26%)
Query: 167 PPGHPSSAASAPVSCSGPPPPPP----------PPVPPPPTGATPPPPPPLPAGGAQGSS 216
PP P+ +SAP SGPPPPPP PP PPPP PPPPP LP+ G
Sbjct: 344 PPPPPALPSSAP---SGPPPPPPSVLGVGPVAPPPPPPPPPPPGPPPPPGLPSDG----D 396
Query: 217 HDESSMSGLAAAI-----AGAKLRRVQ---RPEDASG--------------GSSPSGTSK 254
H + +G AA+ GA+L++V+ RP SG S G
Sbjct: 397 HQVPTTAGNKAALLDQIREGAQLKKVEQNSRPVSCSGRDALLDQIRQGIQLKSVADGQES 456
Query: 255 SDANRASSGGGGGGLMEEMNKLLAKRRKAASQSDKPAEKKEDESQMED 302
+ A + G G LME M KR KA SD+ E ++DE ED
Sbjct: 457 TPPTPAPTSGIVGALMEVMQ----KRSKAIHSSDED-EDEDDEEDFED 499
Score = 40.0 bits (92), Expect = 0.004
Identities = 24/55 (43%), Positives = 25/55 (45%), Gaps = 12/55 (21%)
Query: 167 PPGHPSSAASAPVSCSGPP---PPPPP------PVPPP---PTGATPPPPPPLPA 209
PP P S P P PPPPP P PPP PT A PPPPP P+
Sbjct: 277 PPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPS 331
Score = 31.2 bits (69), Expect = 1.8
Identities = 18/77 (23%), Positives = 35/77 (45%), Gaps = 3/77 (3%)
Query: 56 LQDQQVVINYSIVKGLKYNQATPTFHQWRDARQVYGLNFASKEEATTFSNAMLFALNIMN 115
++D +++ + YN FH + LNFA++EEA F A+ +++
Sbjct: 83 IKDGKLLWEQELYNNFVYNSPRGYFHTFAGDTCQVALNFANEEEAKKFRKAV---TDLLG 139
Query: 116 SQEGGPSSQRQVQNGPS 132
++ +R NGP+
Sbjct: 140 RRQRKSEKRRDPPNGPN 156
>gi|22749221 sprouty-related protein 1 with EVH-1 domain [Homo
sapiens]
Length = 444
Score = 68.9 bits (167), Expect = 8e-12
Identities = 40/130 (30%), Positives = 66/130 (50%), Gaps = 9/130 (6%)
Query: 4 SEQSICQARASVMVYDDTSKKWVPIKPGQQGFSRINIY-----HNTASNTFRVVGVKLQD 58
++ S + RA VM DD+S W+P+ G G S + ++ F + G +L+D
Sbjct: 10 NDNSYARVRAVVMTRDDSSGGWLPL--GGSGLSSVTVFKVPHQEENGCADFFIRGERLRD 67
Query: 59 QQVVINYSIVKGLKYNQATPTFHQWRDARQVYGLNFASKEEATTFSNAMLFALNIMNSQE 118
+ VV+ + K L YN+ TPTFH W+ + +GL F S +A F + A I + +
Sbjct: 68 KMVVLECMLKKDLIYNKVTPTFHHWKIDDKKFGLTFQSPADARAFDRGIRRA--IEDISQ 125
Query: 119 GGPSSQRQVQ 128
G P S+ + +
Sbjct: 126 GCPESKNEAE 135
>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
sapiens]
Length = 483
Score = 66.6 bits (161), Expect = 4e-11
Identities = 45/146 (30%), Positives = 61/146 (41%), Gaps = 13/146 (8%)
Query: 184 PPPPPPPPVPPPPTGATPPPPPPLPAGGAQGSSHDESSMSGLAAAIA----GAKLRRVQR 239
PPPPPP P PPPP GA PPPPP P SS + G +A +A G +LR+V +
Sbjct: 5 PPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRKVTQ 64
Query: 240 PEDASGGSSPSGTSKSDANRASSGGGGGGLMEEMNKLLAKRRKAASQSDKPAEKKEDESQ 299
D S S + S+ G + L A P + +
Sbjct: 65 INDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFA--------GGFPVLRPAGQRD 116
Query: 300 MEDPSTSPSPGTRAAS-QPPNSSEAG 324
+ T PG+RA S + PN + +G
Sbjct: 117 VAGGKTGQGPGSRAPSPRLPNKTISG 142
Score = 49.7 bits (117), Expect = 5e-06
Identities = 20/47 (42%), Positives = 26/47 (55%)
Query: 162 TGPILPPGHPSSAASAPVSCSGPPPPPPPPVPPPPTGATPPPPPPLP 208
+GP++PP P ++ + PP P VP PP PPPPPPLP
Sbjct: 141 SGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPPLP 187
Score = 45.8 bits (107), Expect = 7e-05
Identities = 25/66 (37%), Positives = 28/66 (42%), Gaps = 19/66 (28%)
Query: 160 SATGPILPPGHPSSAASAPVSCSGPPPPPPPPVPPPPTGAT-----------------PP 202
S GP+ P + PV C+ PPPPPPPP PPP PP
Sbjct: 202 SPPGPLTKGNLP--VVAPPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPP 259
Query: 203 PPPPLP 208
PPPLP
Sbjct: 260 IPPPLP 265
Score = 43.5 bits (101), Expect = 4e-04
Identities = 20/43 (46%), Positives = 24/43 (55%), Gaps = 2/43 (4%)
Query: 164 PILPPGHPSSAASAPVSCSGPPPPPPPPVPPPPTGATPPPPPP 206
P++ P P + + PV P PPPP PPPP TPPP PP
Sbjct: 199 PLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPP--PTPPPLPP 239
Score = 39.7 bits (91), Expect = 0.005
Identities = 24/63 (38%), Positives = 31/63 (49%), Gaps = 18/63 (28%)
Query: 164 PILPP-GHPSSAA--SAPVSCSGPPPPPPPPVPP----PPTGATPPP-----------PP 205
P+LPP G+P A ++P + PP PPPP+PP P + P P PP
Sbjct: 265 PLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPP 324
Query: 206 PLP 208
PLP
Sbjct: 325 PLP 327
Score = 38.5 bits (88), Expect = 0.011
Identities = 21/65 (32%), Positives = 24/65 (36%), Gaps = 24/65 (36%)
Query: 168 PGHPSSAASAPVSCSGPPPPPPPPVP------------------------PPPTGATPPP 203
P P+ A P + PPPP PPP+P PP PPP
Sbjct: 166 PPRPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPP 225
Query: 204 PPPLP 208
PPP P
Sbjct: 226 PPPPP 230
Score = 36.6 bits (83), Expect = 0.043
Identities = 25/56 (44%), Positives = 27/56 (48%), Gaps = 12/56 (21%)
Query: 164 PILPPGHPSSAA--SAPVSCSGP---------PPPPPPPVPPPPTGATPPPPPPLP 208
P LPP PSS+ + VS GP PP P PPPP PP PPPLP
Sbjct: 184 PPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCA-PPPPPPPPPPTPPPLP 238
Score = 35.0 bits (79), Expect = 0.13
Identities = 28/93 (30%), Positives = 36/93 (38%), Gaps = 18/93 (19%)
Query: 159 TSATGPILPPGHPSSAASAPVSCSGPPPPPPPPVPP-------------PPTGA---TPP 202
+S T P LPP PS AP +G P PP PP P G PP
Sbjct: 319 SSETPPPLPPKSPSF--QAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPP 376
Query: 203 PPPPLPAGGAQGSSHDESSMSGLAAAIAGAKLR 235
P PP + + SS + + + G +LR
Sbjct: 377 PAPPARSPTTELSSKSQQATAWTPTQQPGGQLR 409
Score = 34.7 bits (78), Expect = 0.17
Identities = 31/109 (28%), Positives = 38/109 (34%), Gaps = 12/109 (11%)
Query: 154 SLERRTSATGPILPPGHPSSAASAPVSCSGPPPPPPPPVPPPPTGATPPPPPPLPAGGAQ 213
S R S P LP + SS P+ PP P PP GA P PP P G
Sbjct: 301 SCSPRASLPAPPLPGVNSSSETPPPL----PPKSPSFQAPPQKAGAQALPAPPAPPGSQP 356
Query: 214 GSSHDESSMSGLAAAIAGAKLRRVQRPEDASGGSSPSGTSKSDANRASS 262
G G KL P A SP+ S + +A++
Sbjct: 357 FLQKKRHGRPG----AGGGKL----NPPPAPPARSPTTELSSKSQQATA 397
>gi|189571671 sprouty-related protein with EVH-1 domain 2 isoform b
[Homo sapiens]
Length = 415
Score = 63.2 bits (152), Expect = 4e-10
Identities = 49/183 (26%), Positives = 78/183 (42%), Gaps = 24/183 (13%)
Query: 4 SEQSICQARASVMVYDDTSKKWVPIKPGQQGFSRINIY-----HNTASNTFRVVGVKLQD 58
S+ I + +A VM DD+S W P + G G SR+ + + F + G + +D
Sbjct: 6 SDSYIVRVKAVVMTRDDSSGGWFPQEGG--GISRVGVCKVMHPEGNGRSGFLIHGERQKD 63
Query: 59 QQVVINYSIVKGLKYNQATPTFHQWRDARQVYGLNFASKEEATTFSNAMLFALNIMNSQE 118
+ VV+ + K L Y +A PTFH W+ + +GL F S +A F + A I + E
Sbjct: 64 KLVVLECYVRKDLVYTKANPTFHHWKVDNRKFGLTFQSPADARAFDRGVRKA--IEDLIE 121
Query: 119 GGPSSQRQVQNGPSPDEMDIQRRQVMEQHQQQRQESLERRTSATGPILPPGHPSSAASAP 178
G +S + N E ++ V S ++R P+ S+P
Sbjct: 122 GSTTSSSTIHN-----EAELGDDDVFTTATDSSSNSSQKRE----------QPTRTISSP 166
Query: 179 VSC 181
SC
Sbjct: 167 TSC 169
>gi|88853871 sprouty-related, EVH1 domain containing 3 isoform b
[Homo sapiens]
Length = 152
Score = 63.2 bits (152), Expect = 4e-10
Identities = 40/133 (30%), Positives = 62/133 (46%), Gaps = 11/133 (8%)
Query: 10 QARASVMVYDDTSKKWVPIKPGQQGFSRINIYH--------NTASNTFRVVGVKLQDQQV 61
+ RA VM DD+S W+P+ G G S++++ + + G +L+DQ+
Sbjct: 3 RVRAVVMARDDSSGGWLPVGGG--GLSQVSVCRVRGARPEGGARQGHYVIHGERLRDQKT 60
Query: 62 VINYSIVKGLKYNQATPTFHQWRDARQVYGLNFASKEEATTFSNAMLFALNIMNSQEGGP 121
+ ++ GL YN+ P FH W +GL F S EA F ++L AL + P
Sbjct: 61 TLECTLKPGLVYNKVNPIFHHWSLGDCKFGLTFQSPAEADEFQKSLLAALAALGRGSLTP 120
Query: 122 SSQRQVQNGPSPD 134
SS + PS D
Sbjct: 121 SSSSS-SSSPSQD 132
>gi|189571669 sprouty-related protein with EVH-1 domain 2 isoform a
[Homo sapiens]
Length = 418
Score = 61.6 bits (148), Expect = 1e-09
Identities = 48/179 (26%), Positives = 76/179 (42%), Gaps = 24/179 (13%)
Query: 8 ICQARASVMVYDDTSKKWVPIKPGQQGFSRINIY-----HNTASNTFRVVGVKLQDQQVV 62
I + +A VM DD+S W P + G G SR+ + + F + G + +D+ VV
Sbjct: 13 IVRVKAVVMTRDDSSGGWFPQEGG--GISRVGVCKVMHPEGNGRSGFLIHGERQKDKLVV 70
Query: 63 INYSIVKGLKYNQATPTFHQWRDARQVYGLNFASKEEATTFSNAMLFALNIMNSQEGGPS 122
+ + K L Y +A PTFH W+ + +GL F S +A F + A I + EG +
Sbjct: 71 LECYVRKDLVYTKANPTFHHWKVDNRKFGLTFQSPADARAFDRGVRKA--IEDLIEGSTT 128
Query: 123 SQRQVQNGPSPDEMDIQRRQVMEQHQQQRQESLERRTSATGPILPPGHPSSAASAPVSC 181
S + N E ++ V S ++R P+ S+P SC
Sbjct: 129 SSSTIHN-----EAELGDDDVFTTATDSSSNSSQKRE----------QPTRTISSPTSC 172
>gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens]
Length = 502
Score = 61.2 bits (147), Expect = 2e-09
Identities = 43/155 (27%), Positives = 66/155 (42%), Gaps = 41/155 (26%)
Query: 159 TSATGPILPPGHPSSAASAPVSCSGPP-PPPPPPVPPPPTGATPPPPPPLP--------- 208
T +GP+ PP P GPP PPPPPP PPPP+ P PPPLP
Sbjct: 375 TGRSGPLPPP---------PPGAGGPPMPPPPPPPPPPPSSGNGPAPPPLPPALVPAGGL 425
Query: 209 -AGGAQGSSHDESSMSGLAAAIAGAKLRRVQRPEDASGGSSPSGTSKSDANRASSGGGGG 267
GG +G+ D+ G +L + ++S P +S+
Sbjct: 426 APGGGRGALLDQIRQ--------GIQLNKTPGAPESSALQPPPQSSE------------- 464
Query: 268 GLMEEMNKLLAKRRKAASQSDKPAEKKEDESQMED 302
GL+ + ++ KR +A SD+ ++ DE + ++
Sbjct: 465 GLVGALMHVMQKRSRAIHSSDEGEDQAGDEDEDDE 499
Score = 46.2 bits (108), Expect = 5e-05
Identities = 22/51 (43%), Positives = 25/51 (49%)
Query: 164 PILPPGHPSSAASAPVSCSGPPPPPPPPVPPPPTGATPPPPPPLPAGGAQG 214
P + G+ + P G PPPP P PPP G PPPPP PA G G
Sbjct: 329 PPIVGGNKGRSGPLPPVPLGIAPPPPTPRGPPPPGRGGPPPPPPPATGRSG 379
Score = 34.7 bits (78), Expect = 0.17
Identities = 22/78 (28%), Positives = 37/78 (47%), Gaps = 2/78 (2%)
Query: 56 LQDQQVVINYSIVKGLKYNQATPTFHQWRDARQVYGLNFASKEEATTFSNAMLFALNIMN 115
LQ +++ + L Y+ TP FH + GLNFA ++EA F + + N
Sbjct: 90 LQAGRLLWEQELYSQLVYSTPTPFFHTFAGDDCQAGLNFADEDEAQAFRALVQEKIQKRN 149
Query: 116 SQEGGPSSQRQVQNGPSP 133
++ G +RQ+ P+P
Sbjct: 150 QRQSG--DRRQLPPPPTP 165
Score = 30.4 bits (67), Expect = 3.1
Identities = 19/50 (38%), Positives = 20/50 (40%), Gaps = 24/50 (48%)
Query: 185 PPPPPP---------------------PVPPPPTGATPPPP-P--PLPAG 210
PPPPPP P+PP P G PPPP P P P G
Sbjct: 314 PPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRGPPPPG 363
Score = 30.0 bits (66), Expect = 4.1
Identities = 14/29 (48%), Positives = 16/29 (55%), Gaps = 1/29 (3%)
Query: 188 PPPPVPPPPTGATPPPPPPLPAGGAQGSS 216
P PP PPP G P PP+ GG +G S
Sbjct: 312 PLPPPPPPSRGGNQLPRPPI-VGGNKGRS 339
>gi|32698936 B-cell CLL/lymphoma 9-like [Homo sapiens]
Length = 1499
Score = 61.2 bits (147), Expect = 2e-09
Identities = 66/286 (23%), Positives = 107/286 (37%), Gaps = 48/286 (16%)
Query: 152 QESLERRTSATGPILPPGHPSSAASAPVSCSGPPPPPPPPVPPPPTGATPPPPPPLPAGG 211
Q+++ R P +PP S P +G P PPP+PPPP A PP LP G
Sbjct: 268 QQNVPRAKLDQAPKVPPTPEPLPLSTP--SAGTPQSQPPPLPPPPPPAPGSAPPALPPEG 325
Query: 212 AQGSSHDESSMSGLAAAIAGAKLRRVQRPEDASGGSSPSGTSKSDANR------------ 259
S + + + + AA G +GG+ P+ + + AN
Sbjct: 326 PPEDSSQDLAPNSVGAASTGG----------GTGGTHPNTPTATTANNPLPPGGDPSSAP 375
Query: 260 --------ASSGGGGGGLM--EEMNKLLAKRRKAASQSDKPAEK-----KEDESQMEDPS 304
A+ G G L+ E ++K + R+ + Q+ + E+ E E ++ P
Sbjct: 376 GPALLGEAAAPGNGQRSLVGSEGLSKEQLEHRERSLQTLRDIERLLLRSGETEPFLKGPP 435
Query: 305 TSPSPGTRAASQPPNSSEAGRKPWERSNSVEKPVSSILSRTPSVAKSPEAKSPLQSQPHS 364
G A PP + P E+P+ S++S+T S+ P P
Sbjct: 436 GGAGEGGPPAQAPPPPQQPPTAPPSGLKKYEEPLQSMISQTQSLGGPPLEHEVPGHPPGG 495
Query: 365 RMKPAGSVNDMALDAFDLDRMKQE------ILEEVVRELHKVKEEI 404
M G +M + D + E + EE E + +E+I
Sbjct: 496 DM---GQQMNMMIQRLGQDSLTPEQVAWRKLQEEYYEEKRRKEEQI 538
Score = 32.3 bits (72), Expect = 0.82
Identities = 37/148 (25%), Positives = 50/148 (33%), Gaps = 19/148 (12%)
Query: 112 NIMNSQEGGPSSQRQVQNGPSPDEMDIQRRQVMEQHQQQRQESLERRTSATGPILPPGHP 171
N M GGP S GP P Q + QQ GP L +P
Sbjct: 1200 NSMMMAPGGPDSLN-APCGPVPSSS--QMMPFPPRLQQPHGAMAPTGGGGGGPGLQQHYP 1256
Query: 172 SSAASAPVSCSGPPPPPPPPVPPPPTGATPPPPPPLPAGGAQGSSHDESSMSGLAAAIAG 231
S A P PP P PP A G G ++ + G+A+ +
Sbjct: 1257 SGMALPPEDLPNQPPGPMPPQQHLMGKA---------MAGRMGDAYPPGVLPGVASVLND 1307
Query: 232 AKLRRVQRPEDASGGSSPSGTSKSDANR 259
+L V RP +P+G + D +R
Sbjct: 1308 PELSEVIRP-------TPTGIPEFDLSR 1328
>gi|47132519 Ras association and pleckstrin homology domains 1
isoform 1 [Homo sapiens]
Length = 1250
Score = 60.5 bits (145), Expect = 3e-09
Identities = 36/106 (33%), Positives = 52/106 (49%), Gaps = 10/106 (9%)
Query: 139 QRRQVMEQHQQQRQESLERRTSATGPILPPGHPSSAASAPVSCSGPPPPPPPPVPPPPTG 198
+R +E+ + R ES+ R ++ ++PP P P + S P PP PPP PPPP
Sbjct: 582 KRGTQLEESSKARMESMNRPYTS---LVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPP 638
Query: 199 ATPPPPPPLPAGGAQGSSHDESSMSGLAAAIAGAKLRRVQRPEDAS 244
PPPPPP P +S+ S +AA K + R ++AS
Sbjct: 639 PPPPPPPPPPL-------PSQSAPSAGSAAPMFVKYSTITRLQNAS 677
Score = 45.8 bits (107), Expect = 7e-05
Identities = 46/182 (25%), Positives = 63/182 (34%), Gaps = 28/182 (15%)
Query: 131 PSPDEMDIQR-RQVMEQHQQQRQESLERRTSATGPILPPGHPSSAASAPVSCSGPPPPPP 189
P+P M+ Q + V Q +++ + +P P P S PPPPP
Sbjct: 873 PTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPP 932
Query: 190 PPVPPPPTGATPPPPPPLPAGGAQGSSHDESSMSGLAAAIAGAKLRRVQRPEDASGGSSP 249
PVP PP PPPP P GS G K + P GG P
Sbjct: 933 SPVPAPP---PPPPPTASPTPDKSGS--------------PGKKTSKTSSP----GGKKP 971
Query: 250 SGTSKSDANRASSGGGGGGLMEEMNKLLAKRRKAASQSDKPAEK-KEDESQMEDPSTSPS 308
T + +++ SS G E S+ PAE + + P+ P
Sbjct: 972 PPTPQRNSSIKSSSGA-----EHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPK 1026
Query: 309 PG 310
PG
Sbjct: 1027 PG 1028
Score = 42.0 bits (97), Expect = 0.001
Identities = 48/216 (22%), Positives = 69/216 (31%), Gaps = 27/216 (12%)
Query: 168 PGHPSSAASAPVSCSGPPPPPPPPVPP---------------PPTGATPPPPPPLPAGGA 212
P S+ APV PP P PPVPP PPT P PPP LP +
Sbjct: 786 PAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQS 845
Query: 213 QGSSHDESSMSGLAAAIAGAKLRRVQRPEDASGGSSPSGTSKSDANRASSGGGGGGLMEE 272
+ S +S + + + + P + S P ++ S +
Sbjct: 846 FCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQ 905
Query: 273 MNKLLAKRRKAASQSDKPAEKKEDESQMEDPSTSPSPG------TRAASQPPNSSEAGRK 326
+ + D P E P SP P A+ P S G+K
Sbjct: 906 PSSI------PVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKK 959
Query: 327 PWERSNSVEKPVSSILSRTPSVAKSPEAKSPLQSQP 362
+ S+ K R S+ S A+ P +P
Sbjct: 960 TSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRP 995
Score = 37.0 bits (84), Expect = 0.033
Identities = 24/84 (28%), Positives = 28/84 (33%), Gaps = 36/84 (42%)
Query: 162 TGPILPPGHPSSAASAPVSCSGPPPPPPPP------------------------VPPPP- 196
T P++ P + PPPPPPPP PPPP
Sbjct: 688 TPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPL 747
Query: 197 -----------TGATPPPPPPLPA 209
TPPPPPP+PA
Sbjct: 748 KIHQVQHITQVAPPTPPPPPPIPA 771
Score = 35.8 bits (81), Expect = 0.074
Identities = 27/89 (30%), Positives = 30/89 (33%), Gaps = 26/89 (29%)
Query: 146 QHQQQRQESLERRTSATGPILPPGHPSSAASA-----PVSC-------SGPPPP------ 187
Q Q + + L P PP P + SA P C S PPPP
Sbjct: 693 QSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQV 752
Query: 188 --------PPPPVPPPPTGATPPPPPPLP 208
P PP PPP PP PP P
Sbjct: 753 QHITQVAPPTPPPPPPIPAPLPPQAPPKP 781
Score = 31.6 bits (70), Expect = 1.4
Identities = 19/52 (36%), Positives = 24/52 (46%), Gaps = 6/52 (11%)
Query: 164 PILPPGHPSSAASAPVSCSGPPPPPPPPVPP--PPTGATPPPPPPLPAGGAQ 213
P+ PP P + C+ PPP P PVP + PPPP PA +Q
Sbjct: 834 PVPPPTLPKQQSF----CAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQ 881
Score = 30.8 bits (68), Expect = 2.4
Identities = 19/54 (35%), Positives = 20/54 (37%), Gaps = 24/54 (44%)
Query: 184 PPPPPPPPVPPPP-----------------------TGATPP-PPPPLPAGGAQ 213
PPPPPP P P PP T A PP P PP+P Q
Sbjct: 763 PPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQ 816
>gi|150378503 leiomodin 2 (cardiac) [Homo sapiens]
Length = 547
Score = 58.9 bits (141), Expect = 8e-09
Identities = 35/99 (35%), Positives = 50/99 (50%), Gaps = 26/99 (26%)
Query: 136 MDIQRRQVMEQHQQQ---------RQESLERRTSATGPILPPGHP-----------SSAA 175
MD QR++ +++ +QQ R + +R T ++ P + P H +
Sbjct: 352 MDKQRQKRLQEQKQQEGYDGGPNLRTKVWQRGTPSSSPYVSPRHSPWSSPKLPKKVQTVR 411
Query: 176 SAPVS-CSGPPPPPPPPVPPPPTG-----ATPPPPPPLP 208
S P+S + PPPPPPPP PPPP+ PPPPPPLP
Sbjct: 412 SRPLSPVATPPPPPPPPPPPPPSSQRLPPPPPPPPPPLP 450
>gi|7657387 CCR4-NOT transcription complex, subunit 3 [Homo sapiens]
Length = 753
Score = 58.9 bits (141), Expect = 8e-09
Identities = 79/315 (25%), Positives = 117/315 (37%), Gaps = 55/315 (17%)
Query: 131 PSPDEMDIQRRQVMEQHQQQRQESLERRTSATG--PILPPGHPSSAASAPVSCSGPPPPP 188
PSP + + ++ + + + + G P+ HP S A P SGPPP
Sbjct: 272 PSPANCTTENSEDDKKRGRSTDSEVSQSPAKNGSKPVHSNQHPQSPAVPPTYPSGPPPAA 331
Query: 189 PPPVPPPPTGATPPPPPPLPAGGAQGS---SHDESSMSGLAAAIA-----GAKLRRVQRP 240
P P P P A G + S SH+ + + A A+A G + + P
Sbjct: 332 SALSTTPGNNGVPAPAAPPSALGPKASPAPSHNSGTPAPYAQAVAPPAPSGPSTTQPRPP 391
Query: 241 --EDASGGSSPSGTSKSDANRASSGGGGGGLMEEMNKLLAKRRKAASQS----DKPAE-- 292
+ + GG SG S ++ SS GGG G K+ A S S D PAE
Sbjct: 392 SVQPSGGGGGGSGGGGSSSSSNSSAGGGAG----------KQNGATSYSSVVADSPAEVA 441
Query: 293 -----KKEDESQMEDPSTSPSPGTRAASQPPNSS----EAGRKPWERSNS------VEKP 337
SQ P + P + S+ P+++ G P +NS V P
Sbjct: 442 LSSSGGNNASSQALGPPSGPHNPPPSTSKEPSAAAPTGAGGVAPGSGNNSGGPSLLVPLP 501
Query: 338 VSSILSRTPSVAKSPEAKSPLQSQPH-------SRMKPAGSVNDMALDAFDLDRMKQEIL 390
V+ S TPS + + A + L P +P S+ MA A +
Sbjct: 502 VNPPSSPTPSFSDAKAAGALLNGPPQFSTAPEIKAPEPLSSLKSMAERA-----AISSGI 556
Query: 391 EEVVRELHKVKEEII 405
E+ V LH + +II
Sbjct: 557 EDPVPTLHLTERDII 571
>gi|110431370 espin [Homo sapiens]
Length = 854
Score = 58.5 bits (140), Expect = 1e-08
Identities = 69/239 (28%), Positives = 90/239 (37%), Gaps = 39/239 (16%)
Query: 165 ILPPGH-PSSAASAP-VSCSGPPPPPPPPVPPPPTGATPPPPPPLPAGGAQGSSHDESSM 222
+LP H P+ A+ P S PPPPPPPP P P ++PPP PPLP
Sbjct: 575 LLPGNHVPNGCAADPKASRELPPPPPPPPPPLPEAASSPPPAPPLP-------------- 620
Query: 223 SGLAAAIAGAKLRRVQRPEDASGGSSPSGTSKSDANRASSGGGGGGLMEEMNKLLAKRRK 282
L +A G RR SS +G++KS N S G L+ E+ K K
Sbjct: 621 --LESAGPGCGQRR---------SSSSTGSTKS-FNMMSPTGDNSELLAEIK--AGKSLK 666
Query: 283 AASQSDKPAEKKEDESQMEDPSTSPSPGTRAASQP---PNSSEAGRKPWERSNSVEKPVS 339
QS Q SP P A P P AG +P + V P +
Sbjct: 667 PTPQSKGLTTVFSGIGQPAFQPDSPLPSVSPALSPVRSPTPPAAGFQPLLNGSLVPVPPT 726
Query: 340 SILSRTPSVAKSPEAKSPL---QSQPHSRMKPAGSVNDMALDAFDLDRMKQEILEEVVR 395
+ P V EA P Q +P K V M L + + +++ EE R
Sbjct: 727 ---TPAPGVQLDVEALIPTHDEQGRPIPEWKRQVMVRKMQLKMQEEEEQRRKEEEEEAR 782
Score = 45.8 bits (107), Expect = 7e-05
Identities = 51/202 (25%), Positives = 71/202 (35%), Gaps = 39/202 (19%)
Query: 184 PPPPPP--PPVPPPPTGATPPPPP----PLPAGGAQGSSHDESSMSGLAAAIAGAKLRRV 237
PPPPPP PP PPPP PPPPP P P G Q + + + KLR V
Sbjct: 430 PPPPPPSFPPPPPPPGTQLPPPPPGYPAPKPPVGPQAADIYMQTKN---------KLRHV 480
Query: 238 QR---PEDASGGSSPSGTSKSDANRA----SSGGGGGGLMEEMNK-----LLAK------ 279
+ ++ S G + D++R S G ++ + L A+
Sbjct: 481 ETEALKKELSSCDGHDGLRRQDSSRKPRAFSKQPSTGDYYRQLGRCPGETLAARPGMAHS 540
Query: 280 ---RRKAASQSDKPAEKKEDESQMEDPSTSPSPGTRAASQPPNSSEAGRKPWERSNSVEK 336
R + +++ P +E PS P + PN A K S +
Sbjct: 541 EEVRARQPARAGCPRLGPAARGSLEGPSAPPQAALLPGNHVPNGCAADPK---ASRELPP 597
Query: 337 PVSSILSRTPSVAKSPEAKSPL 358
P P A SP PL
Sbjct: 598 PPPPPPPPLPEAASSPPPAPPL 619
Score = 40.0 bits (92), Expect = 0.004
Identities = 33/123 (26%), Positives = 42/123 (34%), Gaps = 24/123 (19%)
Query: 89 VYGLNFASKEEATTFSNAMLFALNIMNSQEGGPSSQRQVQNGPSPDEMDIQRRQVMEQHQ 148
V LNF +T SN + SS ++ P + R ++ +
Sbjct: 363 VQPLNFDLSSPTSTLSN-----------YDSCSSSHSSIKGQHPPCGLSSARAADIQSYM 411
Query: 149 QQRQESLERRTSATGPILPPGHPSSAASAPVSCSGPPPPPPPP---VPPPPTGATPPPPP 205
L G PP P S PPPPPPP +PPPP G P PP
Sbjct: 412 DMLNPELGLPRGTIGKPTPPPPPPSF----------PPPPPPPGTQLPPPPPGYPAPKPP 461
Query: 206 PLP 208
P
Sbjct: 462 VGP 464
Score = 31.6 bits (70), Expect = 1.4
Identities = 17/50 (34%), Positives = 20/50 (40%)
Query: 164 PILPPGHPSSAASAPVSCSGPPPPPPPPVPPPPTGATPPPPPPLPAGGAQ 213
P P P + S +S P PP P G+ P PP PA G Q
Sbjct: 684 PAFQPDSPLPSVSPALSPVRSPTPPAAGFQPLLNGSLVPVPPTTPAPGVQ 733
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 58.2 bits (139), Expect = 1e-08
Identities = 41/166 (24%), Positives = 65/166 (39%), Gaps = 21/166 (12%)
Query: 115 NSQEGGPSSQRQVQNGPSPDEMDIQRRQVMEQHQQQRQESLERRTSATGPILPPGHPSSA 174
+ Q G P ++Q Q ++D + + E+ ++ ++ + + ++P A
Sbjct: 346 SGQGGSPCWKKQEQ------KLDDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEA 399
Query: 175 ASAPVSCSGPPPPPPPPVPPPPTGATPP--PPPPLPAG--------GAQGSSHDESSMSG 224
P + P P PPPP+PPP T PP PPPP P E S
Sbjct: 400 KLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPP 459
Query: 225 LAAAIAGAK-----LRRVQRPEDASGGSSPSGTSKSDANRASSGGG 265
+ A K L QR E + + P GTS +++ GG
Sbjct: 460 VVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGG 505
Score = 45.4 bits (106), Expect = 9e-05
Identities = 53/220 (24%), Positives = 82/220 (37%), Gaps = 46/220 (20%)
Query: 148 QQQRQESLERRTSATGPILPPGHPS--------SAASAPVSCSGPPPPPPPPVPPPP--T 197
Q R + E T PPG P+ + A + + P P PPPPV P T
Sbjct: 204 QAPRSRACEPSTPRRSRGRPPGRPAGPCRRKQQAVVVAEAAVTIPKPEPPPPVVPVKHQT 263
Query: 198 GAT-----PPPPPPLPAGGAQGSSHDESSMS-----GLAAAIAG-AKLRRVQRPEDASGG 246
G+ P P P P G Q S GL I ++ ++V+ + + G
Sbjct: 264 GSWKCKEGPGPGPGTPRRGGQSSRGGRGGRGRGRGGGLPFVIKFVSRAKKVKMGQLSLGL 323
Query: 247 SSPSGTSKSDAN-------RASSGGGGGGLMEEMNKLL---AKRRKAASQSDKPAEKKED 296
S G + + + R SG GG ++ + L + +K + DK E+KE+
Sbjct: 324 ESGQGQGQHEESWQDVPQRRVGSGQGGSPCWKKQEQKLDDEEEEKKEEEEKDKEGEEKEE 383
Query: 297 ESQMED---------------PSTSPSPGTRAASQPPNSS 321
+ E+ P T P+P PP++S
Sbjct: 384 RAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTS 423
Score = 39.3 bits (90), Expect = 0.007
Identities = 23/54 (42%), Positives = 25/54 (46%), Gaps = 2/54 (3%)
Query: 157 RRTSATGPILPPG-HPSSAASAPVSCSGPPPPPPPPVPPPPTGATPPPPP-PLP 208
RR P PP S P++ S P P P PVP PP TPP P PLP
Sbjct: 544 RRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLP 597
Score = 38.9 bits (89), Expect = 0.009
Identities = 13/19 (68%), Positives = 14/19 (73%)
Query: 187 PPPPPVPPPPTGATPPPPP 205
PPPPP PPPP +PPP P
Sbjct: 619 PPPPPAPPPPPAPSPPPAP 637
Score = 37.4 bits (85), Expect = 0.025
Identities = 54/245 (22%), Positives = 88/245 (35%), Gaps = 38/245 (15%)
Query: 167 PPGHPSSAASAPVSCSGPPPPPPPPVPPPPTGATPPPPPPLPAGGAQGSSHDESSMSGLA 226
PP P+ + +AP S + PP P +P PPPPP P S +
Sbjct: 2218 PPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSSGPASPPRQAI- 2276
Query: 227 AAIAGAKLRRVQRPEDASGGSSPS------------GTSKSDANRASSGGGGGGLMEEMN 274
RV+R SG S P+ G + D + G GG M
Sbjct: 2277 ---------RVKRVSTFSGRSPPAPPPYKAPRLDEDGEASEDTPQVPGLGSGGFSRVRMK 2327
Query: 275 KLLAKRRKAASQSDKPAEKKEDESQMEDPSTSPSP---GTRAASQPPN---SSEAGRKPW 328
+ + +PA ++ E P P + PP+ S+
Sbjct: 2328 TPTVRGVLDLDRPGEPAGEESPGPLQERSPLLPLPEDGPPQVPDGPPDLLLESQWHHYSG 2387
Query: 329 ERSNSVEKPVSSILSRTPSVAKSPEAKSPLQSQPHSRMKPAGSVNDMALDAFDLDRMKQE 388
E S+S E+P S E ++P ++ PH R + S + +++A L+ +
Sbjct: 2388 EASSSEEEPPS---------PDDKENQAPKRTGPHLRFE-ISSEDGFSVEAESLEGAWRT 2437
Query: 389 ILEEV 393
++E+V
Sbjct: 2438 LIEKV 2442
Score = 36.2 bits (82), Expect = 0.057
Identities = 15/24 (62%), Positives = 15/24 (62%), Gaps = 4/24 (16%)
Query: 186 PPPPPPVPPPPTGATPPPPPPLPA 209
PPPPP PPPP P PPP PA
Sbjct: 619 PPPPPAPPPPPA----PSPPPAPA 638
Score = 35.4 bits (80), Expect = 0.097
Identities = 28/82 (34%), Positives = 34/82 (41%), Gaps = 13/82 (15%)
Query: 157 RRTSATGPILPPGHPSSAASAPVSCSGPPPPPPP-----PVPP-----PPTGATPPPPPP 206
RR+ P+ P PS AS P+ S PPP + P P G P PPPP
Sbjct: 1911 RRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSPPPP 1970
Query: 207 LPAGGAQGSSHDESSMSGLAAA 228
G D +SGL+AA
Sbjct: 1971 EDLG---PDFEDMEVVSGLSAA 1989
Score = 34.7 bits (78), Expect = 0.17
Identities = 28/88 (31%), Positives = 35/88 (39%), Gaps = 23/88 (26%)
Query: 121 PSSQRQVQNGPSPDEMDIQRRQVMEQHQQQRQESLERRTSATGPILPPGHPSSAASAPVS 180
PS R +P + +RR ++ +E R TS T + PP
Sbjct: 581 PSPPRAPTPPSTPVPLPEKRRSIL-------REPTFRWTSLTRELPPP------------ 621
Query: 181 CSGPPPPPPPPVP-PPPTGATPPPPPPL 207
PP PPPPP P PPP AT P L
Sbjct: 622 ---PPAPPPPPAPSPPPAPATSSRRPLL 646
Score = 33.5 bits (75), Expect = 0.37
Identities = 40/168 (23%), Positives = 57/168 (33%), Gaps = 21/168 (12%)
Query: 171 PSSAASAPVSCSGPPPP------PPPPVPPPPTGATPPPPPPLPA--GGAQGSSHDESSM 222
PSS SA S G P P+PPP P PP PA G +G+ ++
Sbjct: 134 PSSLRSALRSQRGRAPRGRGRKHKTTPLPPPRLADVAPTPPKTPARKRGEEGTERMVQAL 193
Query: 223 SGLAAAIAGAKLRRVQRPEDASGGSSPSGTSKSDANRASSGGGGGGLMEEMNKLLAKRRK 282
+ L LRR Q P+ + T + R G ++ ++A+
Sbjct: 194 TEL--------LRRAQAPQAPRSRACEPSTPRRSRGRPPGRPAGPCRRKQQAVVVAEAAV 245
Query: 283 AASQSDKPAE----KKEDESQMEDPSTSPSPGT-RAASQPPNSSEAGR 325
+ + P K + S P PGT R Q GR
Sbjct: 246 TIPKPEPPPPVVPVKHQTGSWKCKEGPGPGPGTPRRGGQSSRGGRGGR 293
Score = 32.7 bits (73), Expect = 0.63
Identities = 42/158 (26%), Positives = 54/158 (34%), Gaps = 34/158 (21%)
Query: 163 GPILPPGHPSSAASAPVSCSGPPPPPPP----------PVPPPPTGATPP--------PP 204
GP+ PG PSS + P P PP P PPP A+PP P
Sbjct: 1883 GPLPSPGSPSSLTHHIPTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVP 1942
Query: 205 PPLPAGGAQGSSHDESSMSGLAAAIAGAKLRRVQRPEDASGGSSP----SGTSKSDANRA 260
PP A + E + G A + PED SG S +D + A
Sbjct: 1943 PPTSVVTALTPTSGELAPPGPAPS--------PPPPEDLGPDFEDMEVVSGLSAADLDFA 1994
Query: 261 SSGGGGGGLMEEMNKLLAKRRKAASQSDKPAEKKEDES 298
+S G EE + S P + E+ES
Sbjct: 1995 ASLLGTEPFQEE----IVAAGAMGSSHGGPGDSSEEES 2028
Score = 32.0 bits (71), Expect = 1.1
Identities = 44/206 (21%), Positives = 72/206 (34%), Gaps = 28/206 (13%)
Query: 186 PPPPPPVPPPPTGATPPPPPPLPAGGAQGSSHDESSMSGLAA-AIAGAKLRRVQRPEDAS 244
PPP P + PPP +P PPL +++ ++G+ + ++G + + + A
Sbjct: 754 PPPQPQLQPPP---SPQQMPPL----------EKARIAGVGSLPLSGVEEKMFSLLKRAK 800
Query: 245 GGSSPSGTSKSDANRASSGGGGGGLMEEMN---KLLAKRRKAASQSDKPAEKKEDESQME 301
+ AS GG MEE+ K ++ R S+ + K+E S E
Sbjct: 801 VQLFKIDQQQQQKVAASMPLSPGGQMEEVAGAVKQISDRGPVRSEDESVEAKRERPSGPE 860
Query: 302 DPSTSP-----------SPGTRAASQPPNSSEAGRKPWERSNSVEKPVSSILSRTPSVAK 350
P P + G A P + P + +S S T SV
Sbjct: 861 SPVQGPRIKHVCRHAAVALGQARAMVPEDVPRLSALPLRDRQDLATEDTSSASETESVPS 920
Query: 351 SPEAKSPLQSQPHSRMKPAGSVNDMA 376
+ P +P GS +A
Sbjct: 921 RSRRGKVEAAGPGGESEPTGSGGTLA 946
Score = 30.8 bits (68), Expect = 2.4
Identities = 22/71 (30%), Positives = 23/71 (32%), Gaps = 22/71 (30%)
Query: 168 PGHPSSAASAPVSCSGPPPPPPP-PVP---------------------PPPTGATPPPPP 205
P P A P P PP P P+P PPP A PPPP
Sbjct: 571 PPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPA 630
Query: 206 PLPAGGAQGSS 216
P P SS
Sbjct: 631 PSPPPAPATSS 641
Score = 29.3 bits (64), Expect = 6.9
Identities = 18/74 (24%), Positives = 31/74 (41%), Gaps = 2/74 (2%)
Query: 167 PPGHPSSAASAPVSCSGPPPPPPPPVPPPPTGATPPPPPPLPAGGAQGSSHDESSMSGLA 226
PP PS A + +GP PP P P+ AT PP P + ++ ++ +
Sbjct: 472 PPLTPSQRAEREAARAGPEGTSPP--TPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIM 529
Query: 227 AAIAGAKLRRVQRP 240
++ R ++ P
Sbjct: 530 PVVSARSSRVIKTP 543
Score = 29.3 bits (64), Expect = 6.9
Identities = 25/83 (30%), Positives = 28/83 (33%), Gaps = 27/83 (32%)
Query: 162 TGPILPPGHPSSAASAPVSCSG---PPPPPPPPVPPPPTG-------------------- 198
T P L P+S +A SG PP P P P PP G
Sbjct: 1935 TSPQLRVPPPTSVVTALTPTSGELAPPGPAPSPPPPEDLGPDFEDMEVVSGLSAADLDFA 1994
Query: 199 ----ATPPPPPPLPAGGAQGSSH 217
T P + A GA GSSH
Sbjct: 1995 ASLLGTEPFQEEIVAAGAMGSSH 2017
>gi|52485606 formin-like 2 [Homo sapiens]
Length = 1092
Score = 57.8 bits (138), Expect = 2e-08
Identities = 27/52 (51%), Positives = 31/52 (59%), Gaps = 4/52 (7%)
Query: 164 PILPPGH--PSSAASAPVSCSGPPPPPPPPVPPPPTGATPPPPPPLPAGGAQ 213
P LPP P + + PV+ P PPPPPP PPPP PPPPPPLP A+
Sbjct: 531 PPLPPSSDTPETVQNGPVT--PPMPPPPPPPPPPPPPPPPPPPPPLPGPAAE 580
Score = 50.4 bits (119), Expect = 3e-06
Identities = 23/51 (45%), Positives = 30/51 (58%), Gaps = 2/51 (3%)
Query: 160 SATGPILPPGHP--SSAASAPVSCSGPPPPPPPPVPPPPTGATPPPPPPLP 208
+++GP+ PP P S+ + +GP PP PP PPPP PPPPPP P
Sbjct: 521 ASSGPLPPPPPPLPPSSDTPETVQNGPVTPPMPPPPPPPPPPPPPPPPPPP 571
Score = 49.3 bits (116), Expect = 6e-06
Identities = 29/73 (39%), Positives = 35/73 (47%), Gaps = 5/73 (6%)
Query: 159 TSATGPILPPGHPSSAASAPVSCSGPPPPPPPPVPPPPTGATPPPP--PPLPAGGAQGSS 216
T GP+ PP P P PPPPPPPP+P P P PP PPLP+ +
Sbjct: 542 TVQNGPVTPPMPPPPPPPPPPP-PPPPPPPPPPLPGPAAETVPAPPLAPPLPSAPPLPGT 600
Query: 217 HDESSM--SGLAA 227
+ + SGLAA
Sbjct: 601 SSPTVVFNSGLAA 613
Score = 44.7 bits (104), Expect = 2e-04
Identities = 33/114 (28%), Positives = 49/114 (42%), Gaps = 44/114 (38%)
Query: 135 EMDIQRRQVMEQ--HQQQRQESLERRTSATG-----PILPPGHPS--------------- 172
E IQR+ +E+ H+ ++Q +++ + G P++ G S
Sbjct: 459 EEAIQRQSTLEKKIHELEKQGTIKIQKKGDGDIAILPVVASGTLSMGSEVVAGNSVGPTM 518
Query: 173 -SAASAPVSCSGPPPPPP-----------------PPVPPPPTGATPPPPPPLP 208
+A+S P+ PPPPPP PP+PPPP PPPPPP P
Sbjct: 519 GAASSGPL----PPPPPPLPPSSDTPETVQNGPVTPPMPPPPPPPPPPPPPPPP 568
>gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
Length = 653
Score = 57.8 bits (138), Expect = 2e-08
Identities = 65/244 (26%), Positives = 84/244 (34%), Gaps = 47/244 (19%)
Query: 150 QRQESLERRTSATGPILPPGHPSSAASAPVSCSGPPPPPPPPVPPPPTGATPPPPPPLPA 209
QR +R+ A G G P SA S P P P P V A P PP
Sbjct: 312 QRNGGSGQRSGAHG-----GRPGSAHSPP----DKPSSPSPRVRDKAAAAAPTPPARGKE 362
Query: 210 GGAQGSSHDESSMSGLAAAIAGAKLRRVQRPEDASGGSS--------------PSGTSKS 255
+ S+ G AA AG + RR +R + +S P G+S+S
Sbjct: 363 SPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRS 422
Query: 256 DANRASSGGGGGGLMEEMNKLLAKRRKAASQSDKPAEK----------KEDESQMEDPST 305
+ SS G G R A +P + KE + ST
Sbjct: 423 LSRARSSSDSGSG------------RGAPGPGPEPGSERGHGGHGKRAKERPPRARPAST 470
Query: 306 SPSPGTRAASQPPNSSEAGRKPWERSNSVEKPVSSILSRTPSVAKSPE--AKSPLQSQPH 363
SPSPG P + R P S S SR+ S K P ++SP +P
Sbjct: 471 SPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPL 530
Query: 364 SRMK 367
SR K
Sbjct: 531 SRDK 534
>gi|4557329 fas ligand [Homo sapiens]
Length = 281
Score = 57.0 bits (136), Expect = 3e-08
Identities = 28/54 (51%), Positives = 32/54 (59%), Gaps = 7/54 (12%)
Query: 159 TSATGPILPPGH----PSSAASAPVSCSGPPPPPPPPVPPPPTGATPPPPPPLP 208
+SA+ P PPG P+S P PPPPPPPP+PPPP PPP PPLP
Sbjct: 17 SSASSPWAPPGTVLPCPTSVPRRPGQRRPPPPPPPPPLPPPP---PPPPLPPLP 67
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 56.6 bits (135), Expect = 4e-08
Identities = 26/53 (49%), Positives = 30/53 (56%), Gaps = 10/53 (18%)
Query: 166 LPPGHPSSAA----------SAPVSCSGPPPPPPPPVPPPPTGATPPPPPPLP 208
LP G PS ++ S+ + S PPPPPPP PPPP PPPPPPLP
Sbjct: 2376 LPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLP 2428
Score = 50.8 bits (120), Expect = 2e-06
Identities = 58/243 (23%), Positives = 79/243 (32%), Gaps = 14/243 (5%)
Query: 131 PSPDEMDIQRRQVMEQHQQQRQESLERRTSATGPILPPGHPSSAASAPVSCSGPPPPP-- 188
PSP + IQ+ + QQ S GP PP PS G PP
Sbjct: 299 PSPSKPPIQQPTPGKPPAQQPGHE----KSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQ 354
Query: 189 PPPVPPPPTGATPPPPPPLPAGGAQGSSHDESSMSGLAAAIAGAKLRRVQRPEDASGGSS 248
PP PP P PP G++ S ++ LA G Q+P A +
Sbjct: 355 PPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQP-PGVGKTPAQQPGPAKPPTQ 413
Query: 249 PSGTSKSDANRAS--SGGGGGGLMEEMNKLLAKRRKAASQSDKPAEKKEDESQMEDPSTS 306
GT K A + S G + + + A Q+ + + PS
Sbjct: 414 QVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQL 473
Query: 307 PSPGTRAASQPPNSSEAGRKPWERSNSVEKPVSSILSRTPSVAKSPEAKSPLQSQPHSRM 366
P P ++PP KP + KP S T + P P QP S
Sbjct: 474 PGP-----AKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTK 528
Query: 367 KPA 369
P+
Sbjct: 529 PPS 531
Score = 48.9 bits (115), Expect = 8e-06
Identities = 55/223 (24%), Positives = 77/223 (34%), Gaps = 41/223 (18%)
Query: 115 NSQEGGPSSQRQ---VQNGPS--PDEMDIQRRQVMEQHQQQRQESLERRTSATGPILPPG 169
+S++ GP + Q V P+ P +QV +Q L+ A GP P
Sbjct: 382 SSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPV 441
Query: 170 HPSSAASAPVSCSGP---------PPPPPPPVP----PPPTGATPPPPPPLPAGGAQGSS 216
P +GP P PP +P PPP P PPP G A+ S
Sbjct: 442 QQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPS 501
Query: 217 HDESSMSGLAAAIAGAKLRRVQRPEDASGGSSPSGTSKSDANRASSGGGGGGLMEEMNKL 276
S AK Q+P S G++K A + S
Sbjct: 502 QQPGSTKPPPQQPGPAK-PSPQQPGSTKPPSQQPGSAKPSAQQPSPA------------- 547
Query: 277 LAKRRKAASQSDKPAEKKEDESQMEDPSTSPSPGTRAASQPPN 319
+ +A QS KP + ++ P+ SPS A QPP+
Sbjct: 548 ----KPSAQQSTKPVSQTGSGKPLQPPTVSPS-----AKQPPS 581
Score = 46.2 bits (108), Expect = 5e-05
Identities = 17/25 (68%), Positives = 17/25 (68%)
Query: 184 PPPPPPPPVPPPPTGATPPPPPPLP 208
PPPPPPPP PPPP PPP P P
Sbjct: 2411 PPPPPPPPPPPPPPPPLPPPTSPKP 2435
Score = 43.5 bits (101), Expect = 4e-04
Identities = 19/33 (57%), Positives = 20/33 (60%), Gaps = 4/33 (12%)
Query: 174 AASAPVSCSGPPPPPPPPVPPPPTGATPPPPPP 206
+A P PPPPPPPP PPPP PP PPP
Sbjct: 2402 SAQPPPPPPPPPPPPPPPPPPPP----PPLPPP 2430
Score = 41.6 bits (96), Expect = 0.001
Identities = 52/229 (22%), Positives = 72/229 (31%), Gaps = 23/229 (10%)
Query: 163 GPILPPGHPSSAASAPVSCSGPPPP------PPPPVPPPPTGATPP--PPPPLPAGGAQG 214
G PP P A P +G P P PP G TP P P P G
Sbjct: 357 GTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVG 416
Query: 215 SSHDESSMSGLA--AAIAGAKLRRVQRPEDASGGSSPSGTSKSDANRASSGGGGGGLMEE 272
+ + GL A G VQ+P + +G K+ A + L
Sbjct: 417 TPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGP 476
Query: 273 MNKLLAKRRKAASQSDKPAEKKEDESQ--------MEDPSTSPSPGTRAASQPPNSSEAG 324
+ A +P K Q + PSP +++PP+
Sbjct: 477 AKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGS 536
Query: 325 RKPWERSNSVEKPVSSILSRTPSVAKS-----PEAKSPLQSQPHSRMKP 368
KP + S KP + ++ S S P SP QP S+ P
Sbjct: 537 AKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLP 585
Score = 40.8 bits (94), Expect = 0.002
Identities = 57/254 (22%), Positives = 87/254 (34%), Gaps = 63/254 (24%)
Query: 128 QNGPSPDEMDIQRRQVMEQHQQQRQESLERRTSATG-PILPP-----------------G 169
Q GP D + Q+ + Q+ E ++ + TG PI P
Sbjct: 222 QQGPGRDPL--QQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDAS 279
Query: 170 HPSSAASAPVSCSGPPPPPPPPVPPP---PTGATPPPPPPLPAGGAQGSSHDESSMSGLA 226
P + + V P P P PP PT PP P G + + SGL
Sbjct: 280 RPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLT 339
Query: 227 AAIAGAKLRRVQRPEDASGGSSPSGTSKSDANRASSGGGGGGLMEEMNKLLAKRRKAASQ 286
+A Q+P P GT+K A Q
Sbjct: 340 KPLA-------QQPGTVKPPVQPPGTTKPPA----------------------------Q 364
Query: 287 SDKPAEKKEDESQMEDPSTSPSPGTRAASQPPNSSEAGRKPWERSNSVEKPVSSILSRTP 346
PA+ ++ E PS S PG +A +QPP G+ P ++ + P + + P
Sbjct: 365 PLGPAKPPAQQTGSEKPS-SEQPGPKALAQPPG---VGKTPAQQPGPAKPPTQQVGTPKP 420
Query: 347 SVAKSPEAKSPLQS 360
+A+ P +SP ++
Sbjct: 421 -LAQQPGLQSPAKA 433
Score = 40.4 bits (93), Expect = 0.003
Identities = 25/58 (43%), Positives = 26/58 (44%), Gaps = 13/58 (22%)
Query: 151 RQESLERRTSATGPILPPGHPSSAASAPVSCSGPPPPPPPPVPPPPTGATPPPPPPLP 208
R SL+ SA P PP P PPPPPPPP PPP T P P LP
Sbjct: 2395 RSSSLD--ISAQPPPPPPPPPP-----------PPPPPPPPPPPPLPPPTSPKPTILP 2439
Score = 30.8 bits (68), Expect = 2.4
Identities = 44/239 (18%), Positives = 82/239 (34%), Gaps = 37/239 (15%)
Query: 121 PSSQRQVQNGPSPDEMDIQRRQVMEQHQQQRQESLERRTSATGPILPPGHPSSAASAPVS 180
P+S ++ + P P ++QV +++ + + + S P P
Sbjct: 824 PASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPK----PDAKPM-------- 871
Query: 181 CSGPPPPPPPPVPPPPTGATPPPPPPLPAGGAQGSSHDESSMSGLAAAIAGAKLRRVQRP 240
P P PP P P G T P P P Q S +I A + P
Sbjct: 872 ---PKGSPTPPGPRPTAGQTVPTPQQSPKPQEQ-----SRRFSLNLGSITDAPKSQPTTP 923
Query: 241 EDASGGSSPSGTSKSDANRASSGGGGGGLMEEMNKLLAKRRKAA--SQSDKPAEKKEDES 298
++ G G G + + + L++ + SQS A K+ +
Sbjct: 924 QETVTG--------------KLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPA 969
Query: 299 QMEDPSTSPSPGTRAASQPPNSSEAGRKPWERSNSVEKPVSSILSRTPSVAKSPEAKSP 357
+ P++ P + + P + K ++ + EK + + P+V ++ K P
Sbjct: 970 PSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEK-LEPKAEQAPTVKRTETEKKP 1027
Score = 30.0 bits (66), Expect = 4.1
Identities = 33/159 (20%), Positives = 58/159 (36%), Gaps = 27/159 (16%)
Query: 208 PAGGAQGSSHDESSMSGLAAAIAGAKLRRVQRPEDASGGSSPSGTSKSDANRASSGGGGG 267
P G + H S+S +A++I + + + + P + + + K +A G G
Sbjct: 2252 PPDGRASADHIVISLSDMASSIIESVVPKPEGPVADTVSTDLLISEKDPVKKAKKETGNG 2311
Query: 268 GLMEEMNKLLAKRRKAASQSDKPAEKKEDESQMEDPSTSPSPGTRAASQPPNSSEAGRKP 327
++E + E D+ ++E T S PP+S A
Sbjct: 2312 IILEVL------------------EAYRDKKELEAERTKSSLSETVFDHPPSSVIALPMK 2353
Query: 328 WERSNSV---------EKPVSSILSRTPSVAKSPEAKSP 357
+ S + EKP S + S +PSV+ P P
Sbjct: 2354 EQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRP 2392
Score = 29.6 bits (65), Expect = 5.3
Identities = 52/254 (20%), Positives = 81/254 (31%), Gaps = 31/254 (12%)
Query: 119 GGPSSQRQVQNGPSPDEMDIQRRQVMEQHQQQRQESLERRTSATGPILPPGHPSSAA--- 175
GG S + P M+ Q+ E+ ++Q + R +PP S +
Sbjct: 24 GGASGAGSPSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPKGSVPPAAAESPSMHR 83
Query: 176 ------SAPVSCSGPPPPPPPPVPPPPTGATPPPPPPLPAGGAQGSSHDESSMSGLAAAI 229
S P SG PP P P P L + E + G + +
Sbjct: 84 KQELDSSHPPKQSGRPPDPGRPA-----------QPGLSKSRTTDTFRSEQKLPGRSPST 132
Query: 230 AGAK--LRRVQRPEDASGGSSPSGTSKSDANRASSGGGGGGLMEEMNKLLAKRRKAASQS 287
K R E+ P S+ +A A S ++ + N ASQ
Sbjct: 133 ISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVS-----SVVNKFNPFDLISDSEASQE 187
Query: 288 DKPAEKKEDESQMEDPSTSPSPGTRAASQPPNSSEAGRKPWERSNSVEKPVSSILSRTPS 347
+ ++K + + P P + QPP + P + SI S+ P
Sbjct: 188 ETTKKQKVVQKEQGKPEGIIKPPLQ--QQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPE 245
Query: 348 VAKS--PEAKSPLQ 359
KS P P+Q
Sbjct: 246 KIKSQPPGTGKPIQ 259
Score = 28.9 bits (63), Expect = 9.1
Identities = 43/191 (22%), Positives = 75/191 (39%), Gaps = 18/191 (9%)
Query: 220 SSMSGLAAAIAGAKLRRVQRPEDASGGSSPSGTSKSDANRASSGGGGGGLMEEMNKLL-- 277
S M+ ++I G R +D + G + T + +S G G G L + L
Sbjct: 4218 SYMTSSTSSIGGISSRARLLQDDITFGLRKNITDQQKFMGSSLGTGLGTLGNTIRSALQD 4277
Query: 278 -AKRRKAASQSDKPAEKKE-----DESQMEDPSTSPSPGTRAASQPPNSSEAGRKPWERS 331
A + ++ +P+ + D S D S+S ++ + S + R+
Sbjct: 4278 EADKPYSSGSRSRPSSRPSSVYGLDLSIKRDSSSSSLRLKAQEAEALDVSFSHASSSART 4337
Query: 332 NSVEKPVSSILSRTPSVAKSPEAKSPLQ--SQPHSRMK-PAGSVNDMALDAFD------- 381
P+S R P VA++ E +SPL QP + AG + ++ D D
Sbjct: 4338 KPTSLPISQSRGRIPIVAQNSEEESPLSPVGQPMGMARAAAGPLPPISADTRDQFGSSHS 4397
Query: 382 LDRMKQEILEE 392
L ++Q + EE
Sbjct: 4398 LPEVQQHMREE 4408
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 56.6 bits (135), Expect = 4e-08
Identities = 26/53 (49%), Positives = 30/53 (56%), Gaps = 10/53 (18%)
Query: 166 LPPGHPSSAA----------SAPVSCSGPPPPPPPPVPPPPTGATPPPPPPLP 208
LP G PS ++ S+ + S PPPPPPP PPPP PPPPPPLP
Sbjct: 2376 LPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLP 2428
Score = 50.8 bits (120), Expect = 2e-06
Identities = 58/243 (23%), Positives = 79/243 (32%), Gaps = 14/243 (5%)
Query: 131 PSPDEMDIQRRQVMEQHQQQRQESLERRTSATGPILPPGHPSSAASAPVSCSGPPPPP-- 188
PSP + IQ+ + QQ S GP PP PS G PP
Sbjct: 299 PSPSKPPIQQPTPGKPPAQQPGHE----KSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQ 354
Query: 189 PPPVPPPPTGATPPPPPPLPAGGAQGSSHDESSMSGLAAAIAGAKLRRVQRPEDASGGSS 248
PP PP P PP G++ S ++ LA G Q+P A +
Sbjct: 355 PPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQP-PGVGKTPAQQPGPAKPPTQ 413
Query: 249 PSGTSKSDANRAS--SGGGGGGLMEEMNKLLAKRRKAASQSDKPAEKKEDESQMEDPSTS 306
GT K A + S G + + + A Q+ + + PS
Sbjct: 414 QVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQL 473
Query: 307 PSPGTRAASQPPNSSEAGRKPWERSNSVEKPVSSILSRTPSVAKSPEAKSPLQSQPHSRM 366
P P ++PP KP + KP S T + P P QP S
Sbjct: 474 PGP-----AKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTK 528
Query: 367 KPA 369
P+
Sbjct: 529 PPS 531
Score = 48.9 bits (115), Expect = 8e-06
Identities = 55/223 (24%), Positives = 77/223 (34%), Gaps = 41/223 (18%)
Query: 115 NSQEGGPSSQRQ---VQNGPS--PDEMDIQRRQVMEQHQQQRQESLERRTSATGPILPPG 169
+S++ GP + Q V P+ P +QV +Q L+ A GP P
Sbjct: 382 SSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPV 441
Query: 170 HPSSAASAPVSCSGP---------PPPPPPPVP----PPPTGATPPPPPPLPAGGAQGSS 216
P +GP P PP +P PPP P PPP G A+ S
Sbjct: 442 QQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPS 501
Query: 217 HDESSMSGLAAAIAGAKLRRVQRPEDASGGSSPSGTSKSDANRASSGGGGGGLMEEMNKL 276
S AK Q+P S G++K A + S
Sbjct: 502 QQPGSTKPPPQQPGPAK-PSPQQPGSTKPPSQQPGSAKPSAQQPSPA------------- 547
Query: 277 LAKRRKAASQSDKPAEKKEDESQMEDPSTSPSPGTRAASQPPN 319
+ +A QS KP + ++ P+ SPS A QPP+
Sbjct: 548 ----KPSAQQSTKPVSQTGSGKPLQPPTVSPS-----AKQPPS 581
Score = 46.2 bits (108), Expect = 5e-05
Identities = 17/25 (68%), Positives = 17/25 (68%)
Query: 184 PPPPPPPPVPPPPTGATPPPPPPLP 208
PPPPPPPP PPPP PPP P P
Sbjct: 2411 PPPPPPPPPPPPPPPPLPPPTSPKP 2435
Score = 43.5 bits (101), Expect = 4e-04
Identities = 19/33 (57%), Positives = 20/33 (60%), Gaps = 4/33 (12%)
Query: 174 AASAPVSCSGPPPPPPPPVPPPPTGATPPPPPP 206
+A P PPPPPPPP PPPP PP PPP
Sbjct: 2402 SAQPPPPPPPPPPPPPPPPPPPP----PPLPPP 2430
Score = 41.6 bits (96), Expect = 0.001
Identities = 52/229 (22%), Positives = 72/229 (31%), Gaps = 23/229 (10%)
Query: 163 GPILPPGHPSSAASAPVSCSGPPPP------PPPPVPPPPTGATPP--PPPPLPAGGAQG 214
G PP P A P +G P P PP G TP P P P G
Sbjct: 357 GTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVG 416
Query: 215 SSHDESSMSGLA--AAIAGAKLRRVQRPEDASGGSSPSGTSKSDANRASSGGGGGGLMEE 272
+ + GL A G VQ+P + +G K+ A + L
Sbjct: 417 TPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGP 476
Query: 273 MNKLLAKRRKAASQSDKPAEKKEDESQ--------MEDPSTSPSPGTRAASQPPNSSEAG 324
+ A +P K Q + PSP +++PP+
Sbjct: 477 AKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGS 536
Query: 325 RKPWERSNSVEKPVSSILSRTPSVAKS-----PEAKSPLQSQPHSRMKP 368
KP + S KP + ++ S S P SP QP S+ P
Sbjct: 537 AKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLP 585
Score = 40.8 bits (94), Expect = 0.002
Identities = 57/254 (22%), Positives = 87/254 (34%), Gaps = 63/254 (24%)
Query: 128 QNGPSPDEMDIQRRQVMEQHQQQRQESLERRTSATG-PILPP-----------------G 169
Q GP D + Q+ + Q+ E ++ + TG PI P
Sbjct: 222 QQGPGRDPL--QQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDAS 279
Query: 170 HPSSAASAPVSCSGPPPPPPPPVPPP---PTGATPPPPPPLPAGGAQGSSHDESSMSGLA 226
P + + V P P P PP PT PP P G + + SGL
Sbjct: 280 RPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLT 339
Query: 227 AAIAGAKLRRVQRPEDASGGSSPSGTSKSDANRASSGGGGGGLMEEMNKLLAKRRKAASQ 286
+A Q+P P GT+K A Q
Sbjct: 340 KPLA-------QQPGTVKPPVQPPGTTKPPA----------------------------Q 364
Query: 287 SDKPAEKKEDESQMEDPSTSPSPGTRAASQPPNSSEAGRKPWERSNSVEKPVSSILSRTP 346
PA+ ++ E PS S PG +A +QPP G+ P ++ + P + + P
Sbjct: 365 PLGPAKPPAQQTGSEKPS-SEQPGPKALAQPPG---VGKTPAQQPGPAKPPTQQVGTPKP 420
Query: 347 SVAKSPEAKSPLQS 360
+A+ P +SP ++
Sbjct: 421 -LAQQPGLQSPAKA 433
Score = 40.4 bits (93), Expect = 0.003
Identities = 25/58 (43%), Positives = 26/58 (44%), Gaps = 13/58 (22%)
Query: 151 RQESLERRTSATGPILPPGHPSSAASAPVSCSGPPPPPPPPVPPPPTGATPPPPPPLP 208
R SL+ SA P PP P PPPPPPPP PPP T P P LP
Sbjct: 2395 RSSSLD--ISAQPPPPPPPPPP-----------PPPPPPPPPPPPLPPPTSPKPTILP 2439
Score = 30.8 bits (68), Expect = 2.4
Identities = 44/239 (18%), Positives = 82/239 (34%), Gaps = 37/239 (15%)
Query: 121 PSSQRQVQNGPSPDEMDIQRRQVMEQHQQQRQESLERRTSATGPILPPGHPSSAASAPVS 180
P+S ++ + P P ++QV +++ + + + S P P
Sbjct: 824 PASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPK----PDAKPM-------- 871
Query: 181 CSGPPPPPPPPVPPPPTGATPPPPPPLPAGGAQGSSHDESSMSGLAAAIAGAKLRRVQRP 240
P P PP P P G T P P P Q S +I A + P
Sbjct: 872 ---PKGSPTPPGPRPTAGQTVPTPQQSPKPQEQ-----SRRFSLNLGSITDAPKSQPTTP 923
Query: 241 EDASGGSSPSGTSKSDANRASSGGGGGGLMEEMNKLLAKRRKAA--SQSDKPAEKKEDES 298
++ G G G + + + L++ + SQS A K+ +
Sbjct: 924 QETVTG--------------KLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPA 969
Query: 299 QMEDPSTSPSPGTRAASQPPNSSEAGRKPWERSNSVEKPVSSILSRTPSVAKSPEAKSP 357
+ P++ P + + P + K ++ + EK + + P+V ++ K P
Sbjct: 970 PSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEK-LEPKAEQAPTVKRTETEKKP 1027
Score = 30.0 bits (66), Expect = 4.1
Identities = 33/159 (20%), Positives = 58/159 (36%), Gaps = 27/159 (16%)
Query: 208 PAGGAQGSSHDESSMSGLAAAIAGAKLRRVQRPEDASGGSSPSGTSKSDANRASSGGGGG 267
P G + H S+S +A++I + + + + P + + + K +A G G
Sbjct: 2252 PPDGRASADHIVISLSDMASSIIESVVPKPEGPVADTVSTDLLISEKDPVKKAKKETGNG 2311
Query: 268 GLMEEMNKLLAKRRKAASQSDKPAEKKEDESQMEDPSTSPSPGTRAASQPPNSSEAGRKP 327
++E + E D+ ++E T S PP+S A
Sbjct: 2312 IILEVL------------------EAYRDKKELEAERTKSSLSETVFDHPPSSVIALPMK 2353
Query: 328 WERSNSV---------EKPVSSILSRTPSVAKSPEAKSP 357
+ S + EKP S + S +PSV+ P P
Sbjct: 2354 EQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRP 2392
Score = 29.6 bits (65), Expect = 5.3
Identities = 52/254 (20%), Positives = 81/254 (31%), Gaps = 31/254 (12%)
Query: 119 GGPSSQRQVQNGPSPDEMDIQRRQVMEQHQQQRQESLERRTSATGPILPPGHPSSAA--- 175
GG S + P M+ Q+ E+ ++Q + R +PP S +
Sbjct: 24 GGASGAGSPSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPKGSVPPAAAESPSMHR 83
Query: 176 ------SAPVSCSGPPPPPPPPVPPPPTGATPPPPPPLPAGGAQGSSHDESSMSGLAAAI 229
S P SG PP P P P L + E + G + +
Sbjct: 84 KQELDSSHPPKQSGRPPDPGRPA-----------QPGLSKSRTTDTFRSEQKLPGRSPST 132
Query: 230 AGAK--LRRVQRPEDASGGSSPSGTSKSDANRASSGGGGGGLMEEMNKLLAKRRKAASQS 287
K R E+ P S+ +A A S ++ + N ASQ
Sbjct: 133 ISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVS-----SVVNKFNPFDLISDSEASQE 187
Query: 288 DKPAEKKEDESQMEDPSTSPSPGTRAASQPPNSSEAGRKPWERSNSVEKPVSSILSRTPS 347
+ ++K + + P P + QPP + P + SI S+ P
Sbjct: 188 ETTKKQKVVQKEQGKPEGIIKPPLQ--QQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPE 245
Query: 348 VAKS--PEAKSPLQ 359
KS P P+Q
Sbjct: 246 KIKSQPPGTGKPIQ 259
Score = 28.9 bits (63), Expect = 9.1
Identities = 43/191 (22%), Positives = 75/191 (39%), Gaps = 18/191 (9%)
Query: 220 SSMSGLAAAIAGAKLRRVQRPEDASGGSSPSGTSKSDANRASSGGGGGGLMEEMNKLL-- 277
S M+ ++I G R +D + G + T + +S G G G L + L
Sbjct: 4218 SYMTSSTSSIGGISSRARLLQDDITFGLRKNITDQQKFMGSSLGTGLGTLGNTIRSALQD 4277
Query: 278 -AKRRKAASQSDKPAEKKE-----DESQMEDPSTSPSPGTRAASQPPNSSEAGRKPWERS 331
A + ++ +P+ + D S D S+S ++ + S + R+
Sbjct: 4278 EADKPYSSGSRSRPSSRPSSVYGLDLSIKRDSSSSSLRLKAQEAEALDVSFSHASSSART 4337
Query: 332 NSVEKPVSSILSRTPSVAKSPEAKSPLQ--SQPHSRMK-PAGSVNDMALDAFD------- 381
P+S R P VA++ E +SPL QP + AG + ++ D D
Sbjct: 4338 KPTSLPISQSRGRIPIVAQNSEEESPLSPVGQPMGMARAAAGPLPPISADTRDQFGSSHS 4397
Query: 382 LDRMKQEILEE 392
L ++Q + EE
Sbjct: 4398 LPEVQQHMREE 4408
>gi|82546824 forkhead box K1 [Homo sapiens]
Length = 733
Score = 56.6 bits (135), Expect = 4e-08
Identities = 35/80 (43%), Positives = 45/80 (56%), Gaps = 9/80 (11%)
Query: 155 LERRTSATGPILPPGHPSSAASAPVSCSGPPPPPPPPVPPPPTGATPPPPPPLPAG--GA 212
L R++ P+L ++AA+A + PPP P P PPP G PPPPPPLP G
Sbjct: 14 LALRSAPCSPVLC----AAAAAAAFPAAAPPPAPAQPQPPP--GPPPPPPPPLPPGAIAG 67
Query: 213 QGSSHDESSMSGLAAAIAGA 232
GSS S +SG +A+AGA
Sbjct: 68 AGSSGGSSGVSG-DSAVAGA 86
Score = 42.0 bits (97), Expect = 0.001
Identities = 25/63 (39%), Positives = 33/63 (52%), Gaps = 4/63 (6%)
Query: 177 APVSCSGPPPPPPPPVPPPPTGATPPPPPPLPAGGAQGSSHDESSMSGLAAAIAGAKLRR 236
AP PP PPPPP PP P GA +GG+ G S D S+++G A A+ A
Sbjct: 42 APAQPQPPPGPPPPPPPPLPPGAIAGAG---SSGGSSGVSGD-SAVAGAAPALVAAAAAS 97
Query: 237 VQR 239
V++
Sbjct: 98 VRQ 100
Score = 29.6 bits (65), Expect = 5.3
Identities = 22/66 (33%), Positives = 28/66 (42%), Gaps = 2/66 (3%)
Query: 191 PVPPPPTGATPPPPPPLPAGGAQGSSHD--ESSMSGLAAAIAGAKLRRVQRPEDASGGSS 248
PVP P + P P GA SS+ ++ S L A A ++ D SGG S
Sbjct: 240 PVPSPTGTISVPNSCPASPRGAGSSSYRFVQNVTSDLQLAAEFAAKAASEQQADTSGGDS 299
Query: 249 PSGTSK 254
P SK
Sbjct: 300 PKDESK 305
>gi|157168329 formin 1 [Homo sapiens]
Length = 1196
Score = 55.8 bits (133), Expect = 7e-08
Identities = 31/71 (43%), Positives = 34/71 (47%), Gaps = 15/71 (21%)
Query: 161 ATGPILPPGHPSSAASAPVSCSGPPPPP-PPPVP--------------PPPTGATPPPPP 205
+ GP LPP P P S +GPPPPP PPP+P PPP G PPPPP
Sbjct: 675 SAGPPLPPPPPPPPPLPPPSSAGPPPPPPPPPLPNSPAPPNPGGPPPAPPPPGLAPPPPP 734
Query: 206 PLPAGGAQGSS 216
L G SS
Sbjct: 735 GLFFGLGSSSS 745
Score = 50.8 bits (120), Expect = 2e-06
Identities = 33/91 (36%), Positives = 40/91 (43%), Gaps = 11/91 (12%)
Query: 128 QNGPSPDEMDIQRR-QVMEQHQQQRQESLERRTSATGPILP---------PGHPSSAASA 177
Q P D DI Q ME +Q++L ++ P P P P SA
Sbjct: 617 QLSPPNDHKDIHAALQPMEGMASNQQKALPPPPASIPPPPPLPSGLGSLSPAPPMPPVSA 676
Query: 178 PVSCSGPPPPPPPPVPPPPTGATPPPPPPLP 208
PPPPPP P+PPP + PPPPPP P
Sbjct: 677 GPPLPPPPPPPP-PLPPPSSAGPPPPPPPPP 706
Score = 32.7 bits (73), Expect = 0.63
Identities = 17/51 (33%), Positives = 22/51 (43%), Gaps = 2/51 (3%)
Query: 160 SATGPILPPGHPSSAASAPVSCSGPPPPPPPPVPPPPTGATPPPPPPLPAG 210
S+ + PP +A G +PPPP PPPPPLP+G
Sbjct: 613 SSLSQLSPPNDHKDIHAALQPMEGMASNQQKALPPPPASI--PPPPPLPSG 661
>gi|39812378 RAN binding protein 9 [Homo sapiens]
Length = 729
Score = 55.8 bits (133), Expect = 7e-08
Identities = 48/158 (30%), Positives = 61/158 (38%), Gaps = 40/158 (25%)
Query: 148 QQQRQESLERRTSA-----TGPILPPGHPSSAASAPVSCSG------------------P 184
QQQ+Q+ L A +G +LP SA S+P G P
Sbjct: 12 QQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLGAAAAALLLHP 71
Query: 185 PPPPPPPVPPPPTGATPPPPPPLPAGGAQGSSHDESSMSGLAAAIAGAKLRRVQRPEDAS 244
PPPPPP PP PPPPPP P A + + GLAA P A
Sbjct: 72 PPPPPPATAAPP----PPPPPPPPPASAAAPASGPPAPPGLAAG-----------PGPAG 116
Query: 245 GGSSPSGTSKSDANRASSGGGGGGLMEEMNKLLAKRRK 282
G +P+ + S A A+ G + E K L +R K
Sbjct: 117 GAPTPALVAGSSA--AAPFPHGDSALNEQEKELQRRLK 152
Score = 42.4 bits (98), Expect = 8e-04
Identities = 47/182 (25%), Positives = 61/182 (33%), Gaps = 42/182 (23%)
Query: 182 SGPPPPPPPPVPPPPTGATPPPPPPLPAGGAQGSSHDESSMSGLAAAIAGAKLRRVQRPE 241
SG PPPPPP +PPPP L A ++G L P
Sbjct: 2 SGQPPPPPPQQQQQQQQLSPPPPAAL-------------------APVSGVVL---PAPP 39
Query: 242 DASGGSSPSGTSKSDANRASSGGGGGGLMEEMNKLLAKRRKAASQSDKPAEKKEDESQME 301
S GSSP+G S GGG GG + L A P +
Sbjct: 40 AVSAGSSPAG---------SPGGGAGG------EGLGAAAAALLLHPPPPPPPATAAPPP 84
Query: 302 DPSTSPSPGTRA--ASQPPNSSEAGRKPWERSNSVEKPVSSILSRTPSVAKSPEAKSPLQ 359
P P P + A AS PP P + P ++++ + + A P S L
Sbjct: 85 PPPPPPPPASAAAPASGPPAPPGLAAGPGPAGGA---PTPALVAGSSAAAPFPHGDSALN 141
Query: 360 SQ 361
Q
Sbjct: 142 EQ 143
>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens]
Length = 2161
Score = 55.8 bits (133), Expect = 7e-08
Identities = 76/281 (27%), Positives = 111/281 (39%), Gaps = 71/281 (25%)
Query: 115 NSQEGGP--SSQRQVQNGPSPDEMDIQRRQVMEQHQQQRQESLERRTSATGPILPPGHPS 172
N GGP +S +GPSP + + R+ H +GP LPP H
Sbjct: 955 NPGSGGPLPASSPASFDGPSPPDTRVGSREKSLYH--------------SGP-LPPAHHH 999
Query: 173 SAASAPVSCSGPPPPP------PPPVPPPPTGATPPPPPPLPAGGAQGSSHDESSMSGLA 226
PPP P PP P TG +P PPP A G Q S
Sbjct: 1000 PPHHH--HHHAPPPQPHHHHAHPPHPPEMETGGSPDDPPPRLALGPQPS----------- 1046
Query: 227 AAIAGAKLRRVQRPEDASGGSSPSGTSKSDANRASSGGGGGGLMEEMNKLLAKRRKAASQ 286
+ G + GG SP+ + S ++ S+GGGGG + +AAS
Sbjct: 1047 --LRGWR----------GGGPSPTPGAPSPSHHGSAGGGGGSSQGPALRYFQLPPRAASA 1094
Query: 287 S-DKPAE-------------KKEDESQMEDP-STSPSPGTRAASQPPNSSEAGRKPWERS 331
+ PA K E E Q +PSP + A+ QPP + A P E+
Sbjct: 1095 AMYVPARSGRGRKGPLVKQTKVEGEPQKGGGLPPAPSPTSPASPQPPPAVAA---PSEK- 1150
Query: 332 NSVEKPVSSILSRTPSVAKSPEAK--SPLQSQPHSRMKPAG 370
NS+ P+ +I+ + PS + S + S +++P ++ +P G
Sbjct: 1151 NSI--PIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQPEPTG 1189
Score = 48.9 bits (115), Expect = 8e-06
Identities = 56/227 (24%), Positives = 84/227 (37%), Gaps = 45/227 (19%)
Query: 180 SCSGPP-----------PPPPPPVPPPPTGATP-----------PPPPPLPAGGAQGSSH 217
+CSGPP P PPVP P + P PPPPPLP AQ +
Sbjct: 1802 ACSGPPTAGVAGGPVAVEPEVPPVPLPTASSLPRKLLPWEEGPGPPPPPLPGPLAQPQA- 1860
Query: 218 DESSMSGLAAAIAGAKLRRVQR--PEDASGGSSPSGTSKSDANRASSGGGGGGLMEEMNK 275
S+++ + A+I ++Q+ A+GG+ P S S GG + E +
Sbjct: 1861 --SALATVKASIISELSSKLQQFGGSSAAGGALPWARGGSGGGGDSHHGGASYVPERTSS 1918
Query: 276 LLAKRRKAASQSD--------------KPAEKKEDESQMEDPSTSPSPGTRAASQPPNSS 321
L +R SQS KP P+ + +PG A S +SS
Sbjct: 1919 LQRQRLSDDSQSSLLSKPVSSLFQNWPKPPLPPLPTGTGVSPTAAAAPG--ATSPSASSS 1976
Query: 322 EAGRKPWERSNSVEKPVSSILSRTPSVAKSPEAKSPLQSQPHSRMKP 368
+ + +P +L R PS + P ++ + P P
Sbjct: 1977 STSTRHLQGVEFEMRP--PLLRRAPSPSLLPASEHKVSPAPRPSSLP 2021
Score = 42.0 bits (97), Expect = 0.001
Identities = 27/95 (28%), Positives = 37/95 (38%), Gaps = 17/95 (17%)
Query: 174 AASAPVSCSGPPPPPPPPVPPPPTGATPPPPPPLPAGGAQGSSHDESSMSGLAAAIAGAK 233
A++AP G P PP PP P P A P P P P G G +S S
Sbjct: 1638 ASAAP----GDPHPPGPPAPAAPAPAAPQPGPDPPPGTDSGIEEVDSRSSS--------- 1684
Query: 234 LRRVQRPEDASGGSSPSGTSKSDANRASSGGGGGG 268
P + +S + ++ ++ GGGG G
Sbjct: 1685 ----DHPLETISSASTLSSLSAEGGGSAGGGGGAG 1715
Score = 39.7 bits (91), Expect = 0.005
Identities = 26/94 (27%), Positives = 36/94 (38%)
Query: 164 PILPPGHPSSAASAPVSCSGPPPPPPPPVPPPPTGATPPPPPPLPAGGAQGSSHDESSMS 223
P+ PP S++ P S P PP P P P P PP PPP A SS++
Sbjct: 1566 PLPPPLEFSNSFEKPESPLTPGPPHPLPDTPAPATPLPPVPPPAVAAAPPTLDSTASSLT 1625
Query: 224 GLAAAIAGAKLRRVQRPEDASGGSSPSGTSKSDA 257
+ +A P D P+ + + A
Sbjct: 1626 SYDSEVATLTQGASAAPGDPHPPGPPAPAAPAPA 1659
Score = 37.4 bits (85), Expect = 0.025
Identities = 28/100 (28%), Positives = 33/100 (33%), Gaps = 13/100 (13%)
Query: 170 HPSSAASAPVSCSGPPPPPPPPVPPPPTGATP--PPPPPLPAGGAQGSSHDESSMSGLAA 227
+ S A+ S P P PP PP P P P P P P G + S S
Sbjct: 1627 YDSEVATLTQGASAAPGDPHPPGPPAPAAPAPAAPQPGPDPPPGTDSGIEEVDSRSSSDH 1686
Query: 228 AIAGAKLRRVQRPEDASGGSSPSGTSKSDANRASSGGGGG 267
+ E S S+ S S A GGG G
Sbjct: 1687 PL-----------ETISSASTLSSLSAEGGGSAGGGGGAG 1715
Score = 36.2 bits (82), Expect = 0.057
Identities = 70/266 (26%), Positives = 85/266 (31%), Gaps = 67/266 (25%)
Query: 162 TGPILPPGHPSSAASAP------VSCSG---PPPPPPPPVP----PPPT----------- 197
TG L P P A A S G P PPP PP P PPPT
Sbjct: 1343 TGKALDPASPLGLALAARERALKESSEGGGAPQPPPRPPSPRYEAPPPTPHHHSPHAHHE 1402
Query: 198 ------GATPPPPPPLPAGGAQGSSHDESSMSGLAAAIAGAKLRRVQRPEDASGGSS--- 248
GA+PP P G G E S+ A + L R+ P A G
Sbjct: 1403 PVLRLWGASPPDPARRELGYRAGLGSQEKSLPASPPAARRSLLHRL--PPTAPGVGPLLL 1460
Query: 249 PSGTSKSDANRASSGGGGGGLMEEMNKL------LAKRRKAASQSDKPAEKKEDESQMED 302
GT + S EE +L L + A + ED +
Sbjct: 1461 QLGTEPPAPHPGVSKPWRSAAPEEPERLPLHVRFLENCQPRAPVTSGRGPPSEDGPGVPP 1520
Query: 303 PS----TSPSPGTRAASQ----------PPNSS-----------EAGRKPWERSNSVEKP 337
PS PSP + AS+ PP S E P E SNS EKP
Sbjct: 1521 PSPRRSVPPSPTSPRASEENGLPLLVLPPPAPSVDVEDGEFLFVEPLPPPLEFSNSFEKP 1580
Query: 338 VSSILSRTP-SVAKSPEAKSPLQSQP 362
S + P + +P +PL P
Sbjct: 1581 ESPLTPGPPHPLPDTPAPATPLPPVP 1606
Score = 35.4 bits (80), Expect = 0.097
Identities = 23/82 (28%), Positives = 35/82 (42%), Gaps = 17/82 (20%)
Query: 190 PPVPPPPTGATPPPPPPLPAGGAQGSSHDESSMSGLAAAIAGAKLRRVQRPEDASGGSSP 249
PP P P + A+P PPP + A + S + + ++ P +S G S
Sbjct: 1127 PPAPSPTSPASPQPPPAVAAPSEKNSIPIPTII--------------IKAPSTSSSGRSS 1172
Query: 250 SGTS---KSDANRASSGGGGGG 268
G+S + +GGGGGG
Sbjct: 1173 QGSSTEAEPPTQPEPTGGGGGG 1194
Score = 34.7 bits (78), Expect = 0.17
Identities = 21/54 (38%), Positives = 23/54 (42%), Gaps = 6/54 (11%)
Query: 164 PILPPGHPSSAASAPVSCSGPPPPPPPPVPPPPTGATPPPP------PPLPAGG 211
P L P + S V S PPPP PP P +TPP P P P GG
Sbjct: 899 PYLAPPAMKFSRSLSVPGSEDIPPPPTTSPPEPPYSTPPVPSSSGRLTPSPRGG 952
Score = 33.9 bits (76), Expect = 0.28
Identities = 31/103 (30%), Positives = 39/103 (37%), Gaps = 11/103 (10%)
Query: 167 PPGHPSSAASAPVSCSGPPPPPPPPVPPPPTGATPPPPPPLPAGGAQGSSHDESSMSGLA 226
PP P G P P P + P P +P P P P+G A + D +S G
Sbjct: 1181 PPTQPEPTGGG--GGGGSSPSPAPAMSPVPPSPSPVPTPASPSGPA---TLDFTSQFG-- 1233
Query: 227 AAIAGAKLRRVQRPEDASGGSSPSGTSKSDANRASSGGGGGGL 269
AA+ GA R +A S T + GG GGL
Sbjct: 1234 AALVGAARREGGWQNEARRRS----TLFLSTDAGDEDGGDGGL 1272
Score = 32.0 bits (71), Expect = 1.1
Identities = 33/90 (36%), Positives = 37/90 (41%), Gaps = 7/90 (7%)
Query: 156 ERRTSATGPILPPGHPSSAASAPVSCSGPPPPPPPPVPPPPTGATPPPPPPLPAGGAQGS 215
ER +S L SS S PVS S P PP+PP PTG T P A GA
Sbjct: 1914 ERTSSLQRQRLSDDSQSSLLSKPVS-SLFQNWPKPPLPPLPTG-TGVSPTAAAAPGATSP 1971
Query: 216 SHDESSMS-----GLAAAIAGAKLRRVQRP 240
S SS S G+ + LRR P
Sbjct: 1972 SASSSSTSTRHLQGVEFEMRPPLLRRAPSP 2001
Score = 31.6 bits (70), Expect = 1.4
Identities = 17/39 (43%), Positives = 21/39 (53%), Gaps = 6/39 (15%)
Query: 159 TSATGPILPPGHPSSAASAPVSCSGPPPPPPPPVPPPPT 197
++A G PPG P+ AA AP + P P P PPP T
Sbjct: 1639 SAAPGDPHPPGPPAPAAPAPAA------PQPGPDPPPGT 1671
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 55.5 bits (132), Expect = 9e-08
Identities = 52/207 (25%), Positives = 79/207 (38%), Gaps = 33/207 (15%)
Query: 191 PVPPPPTGATPPPPPPLPAGGAQGSSHDESSMSGLAAAIA----GAKLRR---------- 236
PVPPPP PPPPP + + +++ +G A ++ G KL++
Sbjct: 2 PVPPPPA---PPPPPTFALANTEKPTLNKTEQAGRNALLSDISKGKKLKKTVTNDRSAPI 58
Query: 237 VQRPEDASGGSSPSGTSKSDANRASSGGGGGGLMEEMNKL-LAKRRKAASQSDKPAEKKE 295
+ +P+ A G G GGGGGG L +A + ++
Sbjct: 59 LDKPKGAGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLFQAGMPKLRSTANRD 118
Query: 296 DESQMEDPSTSPSPGTRAASQPPNSSEAG------RKPWERSNSVEKPVSSILSRTPSVA 349
++S P P PG R+ S P S +G P RS E + + P V
Sbjct: 119 NDSGGSRPPLLP-PGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVG 177
Query: 350 KSPEA--------KSPLQSQPHSRMKP 368
P++ P+QS PH+R P
Sbjct: 178 SKPDSIPPPVPSTPRPIQSSPHNRGSP 204
Score = 42.7 bits (99), Expect = 6e-04
Identities = 53/223 (23%), Positives = 82/223 (36%), Gaps = 33/223 (14%)
Query: 158 RTSATGPILPPGHPSS-AASAPVSCSGPPPPPPPPVPP--PPTGATP---PPPPPLPAGG 211
R+++ P PP P +P SGPP P +PP P G+ P PPP P
Sbjct: 134 RSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRP 193
Query: 212 AQGSSHDESSMSGLAAAIAGAKLRRVQRPEDASGGSSPSGTSKSDANRASSGGGGGGLME 271
Q S H+ S + G P S G +P NR ++ GGG
Sbjct: 194 IQSSPHNRGS-----PPVPGG-------PRQPSPGPTP---PPFPGNRGTALGGGSIRQS 238
Query: 272 EMNKLLAKRRKAASQSDKPAEKKEDESQMEDPSTSPSPGTRAASQPPNSSEAGRKPWERS 331
++ ++ S++P ++D P P ++P EA P ++
Sbjct: 239 PLS-------SSSPFSNRPPLPPTPSRALDDKPPPPPP--PVGNRPSIHREAVPPPPPQN 289
Query: 332 NSVEKPVSSILSRTPSVAKSPEAKSPLQSQPHSRMKPAGSVND 374
N KP R + +++P P + P+ S ND
Sbjct: 290 N---KPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGND 329
Score = 42.7 bits (99), Expect = 6e-04
Identities = 37/110 (33%), Positives = 48/110 (43%), Gaps = 26/110 (23%)
Query: 150 QRQESLERRTSATGPILPPGHPSSAASAPVSCSGPPPPPPPPVPPPPTGATP------PP 203
QR SL +S+T P+ PG SGP PPPP PPPP P PP
Sbjct: 336 QRNLSL---SSSTPPLPSPGR-----------SGPLPPPPSERPPPPVRDPPGRSGPLPP 381
Query: 204 PPPLPAGG----AQGSSHDESSMSGLAAAIAGAKLRRVQRPEDASGGSSP 249
PPP+ G A ++ S SG+ + +G R P+ S G+ P
Sbjct: 382 PPPVSRNGSTSRALPATPQLPSRSGVDSPRSGP--RPPLPPDRPSAGAPP 429
Score = 39.7 bits (91), Expect = 0.005
Identities = 34/117 (29%), Positives = 40/117 (34%), Gaps = 33/117 (28%)
Query: 121 PSSQRQVQNGPSPDEMDIQRRQVMEQHQQQRQESLERRTSATGPILPPGHPSSAASAPVS 180
P RQ GP+P R + ++ + P LPP PS A
Sbjct: 207 PGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPT-PSRALD---- 261
Query: 181 CSGPPPPPPP----------PVPPPP-----------------TGATPPPPPPLPAG 210
PPPPPPP VPPPP + A PPPPPP G
Sbjct: 262 -DKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPG 317
Score = 38.1 bits (87), Expect = 0.015
Identities = 32/110 (29%), Positives = 46/110 (41%), Gaps = 24/110 (21%)
Query: 121 PSSQRQVQNGPSPDEMDIQRRQVMEQHQQQRQESLERRTSATGPILPPGHPSSAASAPVS 180
P+ R + + P P + R + H++ + P P PS+++ AP
Sbjct: 254 PTPSRALDDKPPPPPPPVGNRPSI--HREAVPPPPPQNNKPPVPSTP--RPSASSQAPP- 308
Query: 181 CSGPPPPP----PPPVPPPPTG--ATPPPP----------PPLPAGGAQG 214
PPPPP PPP+PP +G TP P PPLP+ G G
Sbjct: 309 ---PPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSG 355
Score = 37.4 bits (85), Expect = 0.025
Identities = 39/181 (21%), Positives = 60/181 (33%), Gaps = 35/181 (19%)
Query: 167 PPGHPSSAASAP-VSCSGPPPPPP-------------------PPVPPPPTGATPPPPPP 206
PP P + P + PPPPP PP PPPP+ PPP PP
Sbjct: 264 PPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPP 323
Query: 207 LPAGGAQGSSHDESSMSGLAAAIAGAKLRRVQRPEDASGGSSPSGTSKSDANRASSGGGG 266
+G + + ++S ++ P G P S+ G
Sbjct: 324 SSSGNDETPRLPQRNLSLSSST--------PPLPSPGRSGPLPPPPSERPPPPVRDPPGR 375
Query: 267 GGLMEEMNKLLAKRRKAASQSDKPAEKKEDESQMEDPSTSPSPGTRAASQPPNSSEAGRK 326
G + + R + S++ + S ++ P + P P PP+ AG
Sbjct: 376 SGPLPPPPPV--SRNGSTSRALPATPQLPSRSGVDSPRSGPRP-----PLPPDRPSAGAP 428
Query: 327 P 327
P
Sbjct: 429 P 429
Score = 34.3 bits (77), Expect = 0.22
Identities = 21/47 (44%), Positives = 22/47 (46%), Gaps = 4/47 (8%)
Query: 159 TSATGPILPPGHPSSAASAPVSCSGPPPPPPPPVPPPPTGATPPPPP 205
TS P P S +P S GP PP PP P GA PPPPP
Sbjct: 391 TSRALPATPQLPSRSGVDSPRS--GPRPPLPP--DRPSAGAPPPPPP 433
Score = 32.7 bits (73), Expect = 0.63
Identities = 25/64 (39%), Positives = 30/64 (46%), Gaps = 16/64 (25%)
Query: 160 SATGPILPPGHPSSAAS----------APVSCSGPPPPPPP---PVPPPPTGATPPPPPP 206
S GP PP PSS+ + +S S PP P P P+PPPP+ PPPP
Sbjct: 314 SRPGP--PPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPS-ERPPPPVR 370
Query: 207 LPAG 210
P G
Sbjct: 371 DPPG 374
Score = 32.3 bits (72), Expect = 0.82
Identities = 49/212 (23%), Positives = 69/212 (32%), Gaps = 24/212 (11%)
Query: 164 PILPPGHPSSAASAPVSCSGPPPPPPPPVPPPPTG-ATPPP-------PPPLPAGGAQGS 215
P+LPPG S++A P S PP P P P G + PP PPP P G++
Sbjct: 127 PLLPPGGRSTSAK-PFS----PPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPD 181
Query: 216 SHDESSMSGLAAAIAGAKLRRVQRPEDASGG---SSPSGTSKSDANRASSGGGGGGLMEE 272
S + I + R P GG SP T + GGG + +
Sbjct: 182 S-IPPPVPSTPRPIQSSPHNRGSPP--VPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQS 238
Query: 273 MNKLLAKRRKAASQSDKPAEKKEDESQMEDPSTSPSPGTRAASQPPNSSEAGRKPWERSN 332
+ P+ +D+ P P + PP + + P +
Sbjct: 239 PLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPST- 297
Query: 333 SVEKPVSSILSRTPSVAKSPEAKSPLQSQPHS 364
P S S+ P P P P S
Sbjct: 298 ----PRPSASSQAPPPPPPPSRPGPPPLPPSS 325
Score = 32.3 bits (72), Expect = 0.82
Identities = 26/90 (28%), Positives = 31/90 (34%), Gaps = 33/90 (36%)
Query: 162 TGPILPPG--HPSSAASAPVSCSGPPPPPPP-----------PVPP----------PPTG 198
+GP+ PP P P SGP PPPPP P P P +G
Sbjct: 354 SGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSG 413
Query: 199 ATPP----------PPPPLPAGGAQGSSHD 218
PP PPPP P+ + D
Sbjct: 414 PRPPLPPDRPSAGAPPPPPPSTSIRNGFQD 443
Score = 30.8 bits (68), Expect = 2.4
Identities = 20/67 (29%), Positives = 28/67 (41%), Gaps = 13/67 (19%)
Query: 128 QNGPSPDEMDIQR-----RQVMEQHQQQRQESLERRTSATGPILPPGHPSSAASAPVSCS 182
++GP P + R R + Q + ++ S P LPP PS+ A
Sbjct: 375 RSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGA------- 427
Query: 183 GPPPPPP 189
PPPPPP
Sbjct: 428 -PPPPPP 433
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 55.5 bits (132), Expect = 9e-08
Identities = 52/207 (25%), Positives = 79/207 (38%), Gaps = 33/207 (15%)
Query: 191 PVPPPPTGATPPPPPPLPAGGAQGSSHDESSMSGLAAAIA----GAKLRR---------- 236
PVPPPP PPPPP + + +++ +G A ++ G KL++
Sbjct: 2 PVPPPPA---PPPPPTFALANTEKPTLNKTEQAGRNALLSDISKGKKLKKTVTNDRSAPI 58
Query: 237 VQRPEDASGGSSPSGTSKSDANRASSGGGGGGLMEEMNKL-LAKRRKAASQSDKPAEKKE 295
+ +P+ A G G GGGGGG L +A + ++
Sbjct: 59 LDKPKGAGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLFQAGMPKLRSTANRD 118
Query: 296 DESQMEDPSTSPSPGTRAASQPPNSSEAG------RKPWERSNSVEKPVSSILSRTPSVA 349
++S P P PG R+ S P S +G P RS E + + P V
Sbjct: 119 NDSGGSRPPLLP-PGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVG 177
Query: 350 KSPEA--------KSPLQSQPHSRMKP 368
P++ P+QS PH+R P
Sbjct: 178 SKPDSIPPPVPSTPRPIQSSPHNRGSP 204
Score = 42.7 bits (99), Expect = 6e-04
Identities = 53/223 (23%), Positives = 82/223 (36%), Gaps = 33/223 (14%)
Query: 158 RTSATGPILPPGHPSS-AASAPVSCSGPPPPPPPPVPP--PPTGATP---PPPPPLPAGG 211
R+++ P PP P +P SGPP P +PP P G+ P PPP P
Sbjct: 134 RSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRP 193
Query: 212 AQGSSHDESSMSGLAAAIAGAKLRRVQRPEDASGGSSPSGTSKSDANRASSGGGGGGLME 271
Q S H+ S + G P S G +P NR ++ GGG
Sbjct: 194 IQSSPHNRGS-----PPVPGG-------PRQPSPGPTP---PPFPGNRGTALGGGSIRQS 238
Query: 272 EMNKLLAKRRKAASQSDKPAEKKEDESQMEDPSTSPSPGTRAASQPPNSSEAGRKPWERS 331
++ ++ S++P ++D P P ++P EA P ++
Sbjct: 239 PLS-------SSSPFSNRPPLPPTPSRALDDKPPPPPP--PVGNRPSIHREAVPPPPPQN 289
Query: 332 NSVEKPVSSILSRTPSVAKSPEAKSPLQSQPHSRMKPAGSVND 374
N KP R + +++P P + P+ S ND
Sbjct: 290 N---KPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGND 329
Score = 42.7 bits (99), Expect = 6e-04
Identities = 37/110 (33%), Positives = 48/110 (43%), Gaps = 26/110 (23%)
Query: 150 QRQESLERRTSATGPILPPGHPSSAASAPVSCSGPPPPPPPPVPPPPTGATP------PP 203
QR SL +S+T P+ PG SGP PPPP PPPP P PP
Sbjct: 336 QRNLSL---SSSTPPLPSPGR-----------SGPLPPPPSERPPPPVRDPPGRSGPLPP 381
Query: 204 PPPLPAGG----AQGSSHDESSMSGLAAAIAGAKLRRVQRPEDASGGSSP 249
PPP+ G A ++ S SG+ + +G R P+ S G+ P
Sbjct: 382 PPPVSRNGSTSRALPATPQLPSRSGVDSPRSGP--RPPLPPDRPSAGAPP 429
Score = 39.7 bits (91), Expect = 0.005
Identities = 34/117 (29%), Positives = 40/117 (34%), Gaps = 33/117 (28%)
Query: 121 PSSQRQVQNGPSPDEMDIQRRQVMEQHQQQRQESLERRTSATGPILPPGHPSSAASAPVS 180
P RQ GP+P R + ++ + P LPP PS A
Sbjct: 207 PGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPT-PSRALD---- 261
Query: 181 CSGPPPPPPP----------PVPPPP-----------------TGATPPPPPPLPAG 210
PPPPPPP VPPPP + A PPPPPP G
Sbjct: 262 -DKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPG 317
Score = 38.1 bits (87), Expect = 0.015
Identities = 32/110 (29%), Positives = 46/110 (41%), Gaps = 24/110 (21%)
Query: 121 PSSQRQVQNGPSPDEMDIQRRQVMEQHQQQRQESLERRTSATGPILPPGHPSSAASAPVS 180
P+ R + + P P + R + H++ + P P PS+++ AP
Sbjct: 254 PTPSRALDDKPPPPPPPVGNRPSI--HREAVPPPPPQNNKPPVPSTP--RPSASSQAPP- 308
Query: 181 CSGPPPPP----PPPVPPPPTG--ATPPPP----------PPLPAGGAQG 214
PPPPP PPP+PP +G TP P PPLP+ G G
Sbjct: 309 ---PPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSG 355
Score = 37.4 bits (85), Expect = 0.025
Identities = 39/181 (21%), Positives = 60/181 (33%), Gaps = 35/181 (19%)
Query: 167 PPGHPSSAASAP-VSCSGPPPPPP-------------------PPVPPPPTGATPPPPPP 206
PP P + P + PPPPP PP PPPP+ PPP PP
Sbjct: 264 PPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPP 323
Query: 207 LPAGGAQGSSHDESSMSGLAAAIAGAKLRRVQRPEDASGGSSPSGTSKSDANRASSGGGG 266
+G + + ++S ++ P G P S+ G
Sbjct: 324 SSSGNDETPRLPQRNLSLSSST--------PPLPSPGRSGPLPPPPSERPPPPVRDPPGR 375
Query: 267 GGLMEEMNKLLAKRRKAASQSDKPAEKKEDESQMEDPSTSPSPGTRAASQPPNSSEAGRK 326
G + + R + S++ + S ++ P + P P PP+ AG
Sbjct: 376 SGPLPPPPPV--SRNGSTSRALPATPQLPSRSGVDSPRSGPRP-----PLPPDRPSAGAP 428
Query: 327 P 327
P
Sbjct: 429 P 429
Score = 34.3 bits (77), Expect = 0.22
Identities = 21/47 (44%), Positives = 22/47 (46%), Gaps = 4/47 (8%)
Query: 159 TSATGPILPPGHPSSAASAPVSCSGPPPPPPPPVPPPPTGATPPPPP 205
TS P P S +P S GP PP PP P GA PPPPP
Sbjct: 391 TSRALPATPQLPSRSGVDSPRS--GPRPPLPP--DRPSAGAPPPPPP 433
Score = 32.7 bits (73), Expect = 0.63
Identities = 25/64 (39%), Positives = 30/64 (46%), Gaps = 16/64 (25%)
Query: 160 SATGPILPPGHPSSAAS----------APVSCSGPPPPPPP---PVPPPPTGATPPPPPP 206
S GP PP PSS+ + +S S PP P P P+PPPP+ PPPP
Sbjct: 314 SRPGP--PPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPS-ERPPPPVR 370
Query: 207 LPAG 210
P G
Sbjct: 371 DPPG 374
Score = 32.3 bits (72), Expect = 0.82
Identities = 49/212 (23%), Positives = 69/212 (32%), Gaps = 24/212 (11%)
Query: 164 PILPPGHPSSAASAPVSCSGPPPPPPPPVPPPPTG-ATPPP-------PPPLPAGGAQGS 215
P+LPPG S++A P S PP P P P G + PP PPP P G++
Sbjct: 127 PLLPPGGRSTSAK-PFS----PPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPD 181
Query: 216 SHDESSMSGLAAAIAGAKLRRVQRPEDASGG---SSPSGTSKSDANRASSGGGGGGLMEE 272
S + I + R P GG SP T + GGG + +
Sbjct: 182 S-IPPPVPSTPRPIQSSPHNRGSPP--VPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQS 238
Query: 273 MNKLLAKRRKAASQSDKPAEKKEDESQMEDPSTSPSPGTRAASQPPNSSEAGRKPWERSN 332
+ P+ +D+ P P + PP + + P +
Sbjct: 239 PLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPST- 297
Query: 333 SVEKPVSSILSRTPSVAKSPEAKSPLQSQPHS 364
P S S+ P P P P S
Sbjct: 298 ----PRPSASSQAPPPPPPPSRPGPPPLPPSS 325
Score = 32.3 bits (72), Expect = 0.82
Identities = 26/90 (28%), Positives = 31/90 (34%), Gaps = 33/90 (36%)
Query: 162 TGPILPPG--HPSSAASAPVSCSGPPPPPPP-----------PVPP----------PPTG 198
+GP+ PP P P SGP PPPPP P P P +G
Sbjct: 354 SGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSG 413
Query: 199 ATPP----------PPPPLPAGGAQGSSHD 218
PP PPPP P+ + D
Sbjct: 414 PRPPLPPDRPSAGAPPPPPPSTSIRNGFQD 443
Score = 30.8 bits (68), Expect = 2.4
Identities = 20/67 (29%), Positives = 28/67 (41%), Gaps = 13/67 (19%)
Query: 128 QNGPSPDEMDIQR-----RQVMEQHQQQRQESLERRTSATGPILPPGHPSSAASAPVSCS 182
++GP P + R R + Q + ++ S P LPP PS+ A
Sbjct: 375 RSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGA------- 427
Query: 183 GPPPPPP 189
PPPPPP
Sbjct: 428 -PPPPPP 433
>gi|126090663 zinc finger homeodomain 4 [Homo sapiens]
Length = 3571
Score = 55.5 bits (132), Expect = 9e-08
Identities = 25/49 (51%), Positives = 28/49 (57%), Gaps = 4/49 (8%)
Query: 160 SATGPILPPGHPSSAASAPVSCSGPPPPPPPPVPPPPTGATPPPPPPLP 208
S+ GP+ P S+ AP PPPPPPPP PPPP PPPPP P
Sbjct: 1975 SSMGPVKIPNTVSTPLQAPPPTPPPPPPPPPPPPPPP----PPPPPSAP 2019
Score = 54.3 bits (129), Expect = 2e-07
Identities = 27/57 (47%), Positives = 31/57 (54%), Gaps = 7/57 (12%)
Query: 164 PILPPGHPSSAASAPV----SCSGP---PPPPPPPVPPPPTGATPPPPPPLPAGGAQ 213
P LPP P ++ PV + S P PPP PPP PPPP PPPPPP P+ Q
Sbjct: 1965 PPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPPPPPPPPPPPPPSAPPQ 2021
Score = 45.4 bits (106), Expect = 9e-05
Identities = 24/74 (32%), Positives = 36/74 (48%), Gaps = 5/74 (6%)
Query: 169 GHPSSAASAP-VSCSGPPPPPPPPVPPPPTGATPPPPPPLPAGGAQGSSHDESSMSGLAA 227
G P+SA S+P +S S P P PPPP PPPPPP P+ G ++ +
Sbjct: 3092 GFPTSATSSPALSLSSAPTKPLLQTPPPP----PPPPPPPPSSSLSGQQTEQQNKESEKK 3147
Query: 228 AIAGAKLRRVQRPE 241
K+++++ E
Sbjct: 3148 QTKPNKVKKIKEEE 3161
Score = 42.0 bits (97), Expect = 0.001
Identities = 20/49 (40%), Positives = 21/49 (42%), Gaps = 24/49 (48%)
Query: 184 PPPPPPPPVP------------------------PPPTGATPPPPPPLP 208
PPPPPPPP+P PPPT PPPPPP P
Sbjct: 1959 PPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPPPP 2007
Score = 37.0 bits (84), Expect = 0.033
Identities = 32/120 (26%), Positives = 54/120 (45%), Gaps = 17/120 (14%)
Query: 247 SSPSGTSKSDANRASSGGGGGGLMEEMNKLLAKRRKAASQSDKPAEKKEDESQMEDPSTS 306
S + +K+ A A+S G G L+ + ++ E ++ + DPS
Sbjct: 2322 SGQTDAAKNAAAPAASSGSGTS-----TPLIPSPKPEPEKTSPKPEYPAEKPKQSDPSP- 2375
Query: 307 PSPGTRAA-------SQPPNSSEAGRKPWERSNSVEKPVSSILSRTPSVAKSPEAKSPLQ 359
PS GT+ A S PP +S A +P + ++P ++ R PS +++P SPLQ
Sbjct: 2376 PSQGTKPALPLASTSSDPPQASTA--QPQPQPQPPKQP--QLIGRPPSASQTPVPSSPLQ 2431
Score = 35.0 bits (79), Expect = 0.13
Identities = 17/33 (51%), Positives = 17/33 (51%), Gaps = 5/33 (15%)
Query: 184 PPPPPPPPVPPPPTGATPPPPPPLPAGGAQGSS 216
P P P PPPP PPPPPLP Q SS
Sbjct: 1949 PISPSSPETPPPP-----PPPPPLPPAPPQPSS 1976
Score = 32.7 bits (73), Expect = 0.63
Identities = 13/27 (48%), Positives = 13/27 (48%)
Query: 184 PPPPPPPPVPPPPTGATPPPPPPLPAG 210
P P PP PPPP P PP P G
Sbjct: 1952 PSSPETPPPPPPPPPLPPAPPQPSSMG 1978
Score = 30.8 bits (68), Expect = 2.4
Identities = 19/65 (29%), Positives = 24/65 (36%), Gaps = 5/65 (7%)
Query: 148 QQQRQESLERRTSATGPILPPGHPSSAASAPVSCSGPPPPPPPPVP-----PPPTGATPP 202
++ +Q + T P LP SS + P P PP P PP TP
Sbjct: 2366 EKPKQSDPSPPSQGTKPALPLASTSSDPPQASTAQPQPQPQPPKQPQLIGRPPSASQTPV 2425
Query: 203 PPPPL 207
P PL
Sbjct: 2426 PSSPL 2430
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.307 0.124 0.353
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,397,337
Number of Sequences: 37866
Number of extensions: 1496839
Number of successful extensions: 66126
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1479
Number of HSP's successfully gapped in prelim test: 1705
Number of HSP's that attempted gapping in prelim test: 17234
Number of HSP's gapped (non-prelim): 21228
length of query: 418
length of database: 18,247,518
effective HSP length: 105
effective length of query: 313
effective length of database: 14,271,588
effective search space: 4467007044
effective search space used: 4467007044
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.