BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|7706581 BRCA2 and CDKN1A-interacting protein isoform BCCIPalpha [Homo sapiens] (322 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|7706581 BRCA2 and CDKN1A-interacting protein isoform BCCIPalp... 641 0.0 gi|17402873 BRCA2 and CDKN1A-interacting protein isoform C [Homo... 573 e-164 gi|17402871 BRCA2 and CDKN1A-interacting protein isoform BCCIPbe... 518 e-147 gi|158631177 homeodomain leucine zipper protein [Homo sapiens] 47 3e-05 gi|58761548 tau tubulin kinase 1 [Homo sapiens] 45 7e-05 gi|21361639 DIPB protein [Homo sapiens] 45 1e-04 gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] 45 1e-04 gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] 45 1e-04 gi|17975763 myelin transcription factor 1 [Homo sapiens] 44 1e-04 gi|60498973 myelin transcription factor 1-like [Homo sapiens] 44 1e-04 gi|55956788 nucleolin [Homo sapiens] 44 3e-04 gi|113204617 skeletal muscle ryanodine receptor isoform 2 [Homo ... 44 3e-04 gi|113204615 skeletal muscle ryanodine receptor isoform 1 [Homo ... 44 3e-04 gi|100816397 MYST histone acetyltransferase (monocytic leukemia)... 44 3e-04 gi|51477718 TATA box binding protein-associated factor, RNA poly... 42 6e-04 gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 famil... 42 7e-04 gi|13654270 LAS1-like [Homo sapiens] 42 0.001 gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 41 0.001 gi|86262149 zinc finger and BTB domain containing 7C [Homo sapiens] 41 0.001 gi|195546900 suppressor of Ty 5 homolog isoform a [Homo sapiens] 41 0.002 gi|161169023 suppressor of Ty 5 homolog isoform a [Homo sapiens] 41 0.002 gi|20149524 suppressor of Ty 5 homolog isoform a [Homo sapiens] 41 0.002 gi|210032580 SET domain containing 1B [Homo sapiens] 41 0.002 gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens] 40 0.002 gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo... 40 0.002 gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens] 40 0.003 gi|58331272 zinc finger, CCHC domain containing 6 [Homo sapiens] 40 0.003 gi|4503257 death-domain associated protein isoform a [Homo sapiens] 40 0.004 gi|215422388 death-domain associated protein isoform a [Homo sap... 40 0.004 gi|215422366 death-domain associated protein isoform b [Homo sap... 40 0.004 >gi|7706581 BRCA2 and CDKN1A-interacting protein isoform BCCIPalpha [Homo sapiens] Length = 322 Score = 641 bits (1654), Expect = 0.0 Identities = 322/322 (100%), Positives = 322/322 (100%) Query: 1 MASRSKRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIE 60 MASRSKRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIE Sbjct: 1 MASRSKRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIE 60 Query: 61 FEAYSLSDNDYDGIKKLLQQLFLKAPVNTAELTDLLIQQNHIGSVIKQTDVSEDSNDDMD 120 FEAYSLSDNDYDGIKKLLQQLFLKAPVNTAELTDLLIQQNHIGSVIKQTDVSEDSNDDMD Sbjct: 61 FEAYSLSDNDYDGIKKLLQQLFLKAPVNTAELTDLLIQQNHIGSVIKQTDVSEDSNDDMD 120 Query: 121 EDEVFGFISLLNLTERKGTQCVEQIQELVLRFCEKNCEKSMVEQLDKFLNDTTKPVGLLL 180 EDEVFGFISLLNLTERKGTQCVEQIQELVLRFCEKNCEKSMVEQLDKFLNDTTKPVGLLL Sbjct: 121 EDEVFGFISLLNLTERKGTQCVEQIQELVLRFCEKNCEKSMVEQLDKFLNDTTKPVGLLL 180 Query: 181 SERFINVPPQIALPMYQQLQKELAGAHRTNKPCGKCYFYLLISKTFVEAGKNNSKKKPSN 240 SERFINVPPQIALPMYQQLQKELAGAHRTNKPCGKCYFYLLISKTFVEAGKNNSKKKPSN Sbjct: 181 SERFINVPPQIALPMYQQLQKELAGAHRTNKPCGKCYFYLLISKTFVEAGKNNSKKKPSN 240 Query: 241 KKKAALMFANAEEEFFYEEQGKPEVLGGPDTRRGLEPVPIQHNGGSRGQVTALVSLKAGL 300 KKKAALMFANAEEEFFYEEQGKPEVLGGPDTRRGLEPVPIQHNGGSRGQVTALVSLKAGL Sbjct: 241 KKKAALMFANAEEEFFYEEQGKPEVLGGPDTRRGLEPVPIQHNGGSRGQVTALVSLKAGL 300 Query: 301 IQSRSTLSDFQGTFMTVGIALS 322 IQSRSTLSDFQGTFMTVGIALS Sbjct: 301 IQSRSTLSDFQGTFMTVGIALS 322 >gi|17402873 BRCA2 and CDKN1A-interacting protein isoform C [Homo sapiens] Length = 292 Score = 573 bits (1477), Expect = e-164 Identities = 285/286 (99%), Positives = 285/286 (99%) Query: 1 MASRSKRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIE 60 MASRSKRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIE Sbjct: 1 MASRSKRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIE 60 Query: 61 FEAYSLSDNDYDGIKKLLQQLFLKAPVNTAELTDLLIQQNHIGSVIKQTDVSEDSNDDMD 120 FEAYSLSDNDYDGIKKLLQQLFLKAPVNTAELTDLLIQQNHIGSVIKQTDVSEDSNDDMD Sbjct: 61 FEAYSLSDNDYDGIKKLLQQLFLKAPVNTAELTDLLIQQNHIGSVIKQTDVSEDSNDDMD 120 Query: 121 EDEVFGFISLLNLTERKGTQCVEQIQELVLRFCEKNCEKSMVEQLDKFLNDTTKPVGLLL 180 EDEVFGFISLLNLTERKGTQCVEQIQELVLRFCEKNCEKSMVEQLDKFLNDTTKPVGLLL Sbjct: 121 EDEVFGFISLLNLTERKGTQCVEQIQELVLRFCEKNCEKSMVEQLDKFLNDTTKPVGLLL 180 Query: 181 SERFINVPPQIALPMYQQLQKELAGAHRTNKPCGKCYFYLLISKTFVEAGKNNSKKKPSN 240 SERFINVPPQIALPMYQQLQKELAGAHRTNKPCGKCYFYLLISKTFVEAGKNNSKKKPSN Sbjct: 181 SERFINVPPQIALPMYQQLQKELAGAHRTNKPCGKCYFYLLISKTFVEAGKNNSKKKPSN 240 Query: 241 KKKAALMFANAEEEFFYEEQGKPEVLGGPDTRRGLEPVPIQHNGGS 286 KKKAALMFANAEEEFFYEEQGKPEVLGGPDTRRGLEPVPIQHNG S Sbjct: 241 KKKAALMFANAEEEFFYEEQGKPEVLGGPDTRRGLEPVPIQHNGWS 286 >gi|17402871 BRCA2 and CDKN1A-interacting protein isoform BCCIPbeta [Homo sapiens] Length = 314 Score = 518 bits (1333), Expect = e-147 Identities = 258/259 (99%), Positives = 259/259 (100%) Query: 1 MASRSKRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIE 60 MASRSKRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIE Sbjct: 1 MASRSKRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIE 60 Query: 61 FEAYSLSDNDYDGIKKLLQQLFLKAPVNTAELTDLLIQQNHIGSVIKQTDVSEDSNDDMD 120 FEAYSLSDNDYDGIKKLLQQLFLKAPVNTAELTDLLIQQNHIGSVIKQTDVSEDSNDDMD Sbjct: 61 FEAYSLSDNDYDGIKKLLQQLFLKAPVNTAELTDLLIQQNHIGSVIKQTDVSEDSNDDMD 120 Query: 121 EDEVFGFISLLNLTERKGTQCVEQIQELVLRFCEKNCEKSMVEQLDKFLNDTTKPVGLLL 180 EDEVFGFISLLNLTERKGTQCVEQIQELVLRFCEKNCEKSMVEQLDKFLNDTTKPVGLLL Sbjct: 121 EDEVFGFISLLNLTERKGTQCVEQIQELVLRFCEKNCEKSMVEQLDKFLNDTTKPVGLLL 180 Query: 181 SERFINVPPQIALPMYQQLQKELAGAHRTNKPCGKCYFYLLISKTFVEAGKNNSKKKPSN 240 SERFINVPPQIALPMYQQLQKELAGAHRTNKPCGKCYFYLLISKTFVEAGKNNSKKKPSN Sbjct: 181 SERFINVPPQIALPMYQQLQKELAGAHRTNKPCGKCYFYLLISKTFVEAGKNNSKKKPSN 240 Query: 241 KKKAALMFANAEEEFFYEE 259 KKKAALMFANAEEEFFYE+ Sbjct: 241 KKKAALMFANAEEEFFYEK 259 >gi|158631177 homeodomain leucine zipper protein [Homo sapiens] Length = 550 Score = 46.6 bits (109), Expect = 3e-05 Identities = 21/50 (42%), Positives = 36/50 (72%) Query: 11 ESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIE 60 +S +PQP + V DEEEE+E E EDD++ ++E++E+D+ D++V I+ Sbjct: 500 DSRLPQPAEVVVCLDEEEEEEEEELPEDDEEEEEEEEEDDDDDDDDVIIQ 549 >gi|58761548 tau tubulin kinase 1 [Homo sapiens] Length = 1321 Score = 45.4 bits (106), Expect = 7e-05 Identities = 24/55 (43%), Positives = 36/55 (65%), Gaps = 6/55 (10%) Query: 15 PQPPDPPVQ------RDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEA 63 PQ P PVQ +EEEE+E E E+E+D++ ++E++EE+E +EE E EA Sbjct: 718 PQVPLAPVQPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEA 772 Score = 40.4 bits (93), Expect = 0.002 Identities = 18/49 (36%), Positives = 32/49 (65%) Query: 14 VPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFE 62 VP P P +EEE+E E ++E++++ ++E++EE+E +EE E E Sbjct: 720 VPLAPVQPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEE 768 Score = 28.9 bits (63), Expect = 6.4 Identities = 12/33 (36%), Positives = 23/33 (69%) Query: 25 DEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEV 57 +EEEE+E E E+E++++ ++E++ V EV Sbjct: 749 EEEEEEEEEEEEEEEEEEEEEEEAAAAVALGEV 781 >gi|21361639 DIPB protein [Homo sapiens] Length = 344 Score = 44.7 bits (104), Expect = 1e-04 Identities = 22/68 (32%), Positives = 37/68 (54%), Gaps = 5/68 (7%) Query: 6 KRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYS 65 + R +ES + + + + EEE E E E ED+ D + E+D E+E+ DE+ E+ + Sbjct: 87 QEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQ-----ESEA 141 Query: 66 LSDNDYDG 73 DN +G Sbjct: 142 EEDNQEEG 149 Score = 31.2 bits (69), Expect = 1.3 Identities = 13/50 (26%), Positives = 28/50 (56%) Query: 23 QRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDNDYD 72 + E+E E ED +++ D+++ E +E EE E E + +++++D Sbjct: 115 EESEDESDEESEEDSEEEMEDEQESEAEEDNQEEGESEAEGETEAESEFD 164 Score = 30.4 bits (67), Expect = 2.2 Identities = 18/62 (29%), Positives = 30/62 (48%), Gaps = 3/62 (4%) Query: 11 ESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDND 70 ES + + + EE+ E E EDE + +++++ EE E E E EA S D + Sbjct: 110 ESETEEESEDESDEESEEDSEEEMEDEQESEAEEDNQEEGE---SEAEGETEAESEFDPE 166 Query: 71 YD 72 + Sbjct: 167 IE 168 Score = 30.0 bits (66), Expect = 2.9 Identities = 15/44 (34%), Positives = 29/44 (65%), Gaps = 1/44 (2%) Query: 27 EEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDND 70 E+E+E+E+E ++ +S++E + E+E EE + E E+ S+ D Sbjct: 86 EQEREIESEAGEESESEEESESEEESETEEES-EDESDEESEED 128 >gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] Length = 709 Score = 44.7 bits (104), Expect = 1e-04 Identities = 21/70 (30%), Positives = 41/70 (58%), Gaps = 2/70 (2%) Query: 3 SRSKRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFE 62 + ++ VE V + D V+ D EE++EV+ + E++++ ++E++EE+E +EE + Sbjct: 198 TENEEEGVEEDVEE--DEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDER 255 Query: 63 AYSLSDNDYD 72 NDYD Sbjct: 256 DQKEEGNDYD 265 Score = 37.0 bits (84), Expect = 0.024 Identities = 16/47 (34%), Positives = 30/47 (63%) Query: 19 DPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYS 65 D V D EEE+E E E+E++++ ++E+ E+DE +E +++ S Sbjct: 222 DEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRS 268 Score = 33.1 bits (74), Expect = 0.34 Identities = 14/42 (33%), Positives = 26/42 (61%) Query: 19 DPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIE 60 D + +EEEE+E E E+E+++ E+D+++E D + E Sbjct: 228 DGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSE 269 Score = 30.4 bits (67), Expect = 2.2 Identities = 15/46 (32%), Positives = 25/46 (54%) Query: 23 QRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSD 68 + +EEEE+E E E E D+ KE+ + + E + E+ S +D Sbjct: 237 EEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTD 282 >gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] Length = 727 Score = 44.7 bits (104), Expect = 1e-04 Identities = 21/70 (30%), Positives = 41/70 (58%), Gaps = 2/70 (2%) Query: 3 SRSKRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFE 62 + ++ VE V + D V+ D EE++EV+ + E++++ ++E++EE+E +EE + Sbjct: 198 TENEEEGVEEDVEE--DEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDER 255 Query: 63 AYSLSDNDYD 72 NDYD Sbjct: 256 DQKEEGNDYD 265 Score = 37.0 bits (84), Expect = 0.024 Identities = 16/47 (34%), Positives = 30/47 (63%) Query: 19 DPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYS 65 D V D EEE+E E E+E++++ ++E+ E+DE +E +++ S Sbjct: 222 DEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRS 268 Score = 33.1 bits (74), Expect = 0.34 Identities = 14/42 (33%), Positives = 26/42 (61%) Query: 19 DPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIE 60 D + +EEEE+E E E+E+++ E+D+++E D + E Sbjct: 228 DGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSE 269 Score = 30.4 bits (67), Expect = 2.2 Identities = 15/46 (32%), Positives = 25/46 (54%) Query: 23 QRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSD 68 + +EEEE+E E E E D+ KE+ + + E + E+ S +D Sbjct: 237 EEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTD 282 >gi|17975763 myelin transcription factor 1 [Homo sapiens] Length = 1121 Score = 44.3 bits (103), Expect = 1e-04 Identities = 39/165 (23%), Positives = 72/165 (43%), Gaps = 9/165 (5%) Query: 5 SKRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEA- 63 SK++ + S + + + +EEEE E E E+E++++ ++E++EE+E +EE E EA Sbjct: 249 SKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAA 308 Query: 64 ---YSLSDNDYDGIKKLLQQLFLKAPVNTAELTDLLIQQNHIGSVIKQTDVSEDSNDDMD 120 D + +K + L+ P + + + + K D + D Sbjct: 309 PDVIFQEDTSHTSAQKAPE---LRGPESPSPKPEYSVIVEVRSDDDKDEDTHSRKSTVTD 365 Query: 121 EDEVFGFISLLNLTERKGTQCVEQIQELVLRFCEKNCEKSMVEQL 165 E E+ ++ NL + Q + E V CE C + QL Sbjct: 366 ESEMQDMMTRGNLGLLE--QAIALKAEQVRTVCEPGCPPAEQSQL 408 Score = 32.3 bits (72), Expect = 0.58 Identities = 13/48 (27%), Positives = 29/48 (60%) Query: 15 PQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFE 62 PQ + + ++K + + +E+D++ ++E++EE+E +EE E E Sbjct: 237 PQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEE 284 >gi|60498973 myelin transcription factor 1-like [Homo sapiens] Length = 1184 Score = 44.3 bits (103), Expect = 1e-04 Identities = 39/138 (28%), Positives = 65/138 (47%), Gaps = 17/138 (12%) Query: 11 ESGVPQPPDPPVQRDEEEEKEVENEDEDDD--DSDKEKDEEDEVIDEEVNIEFEAYSLS- 67 E G D R+EEEE E E+ED+D+D D + E++EE+E +EE E E + ++ Sbjct: 116 EPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNC 175 Query: 68 ------------DNDYDGIKKLLQQLFLKAPVNTAELTDLLIQQNHIGSVIKQTDVSEDS 115 DN+ D +L K+ +N ++ + + S + ++ S Sbjct: 176 HNTRIMQDTEKDDNNNDEYDN-YDELVAKSLLNLGKIAEDAAYRARTESEM-NSNTSNSL 233 Query: 116 NDDMDEDEVFGFISLLNL 133 DD D++E G S L+L Sbjct: 234 EDDSDKNENLGRKSELSL 251 Score = 40.8 bits (94), Expect = 0.002 Identities = 35/129 (27%), Positives = 61/129 (47%), Gaps = 4/129 (3%) Query: 8 RAVESGVPQPPDPPVQRDEEEEKEVENED-EDDDDSDKEKDEEDEVIDEEVNIEFEAYSL 66 +A S V + D D +E++E E E+ +D+D ++DEEDE D E E E Sbjct: 81 KADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEED- 139 Query: 67 SDNDYDG--IKKLLQQLFLKAPVNTAELTDLLIQQNHIGSVIKQTDVSEDSNDDMDEDEV 124 D+D DG ++ ++ + E + H +++ T+ +++ND+ D + Sbjct: 140 EDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDE 199 Query: 125 FGFISLLNL 133 SLLNL Sbjct: 200 LVAKSLLNL 208 >gi|55956788 nucleolin [Homo sapiens] Length = 710 Score = 43.5 bits (101), Expect = 3e-04 Identities = 17/35 (48%), Positives = 28/35 (80%) Query: 22 VQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEE 56 V DE+EE++ E+ED+DDD+ D++ D+ED+ +EE Sbjct: 232 VAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEE 266 Score = 40.8 bits (94), Expect = 0.002 Identities = 17/37 (45%), Positives = 28/37 (75%) Query: 26 EEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFE 62 E+E++E ++EDEDDDD + ++D++DE +EE E E Sbjct: 234 EDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEE 270 Score = 39.7 bits (91), Expect = 0.004 Identities = 38/137 (27%), Positives = 58/137 (42%), Gaps = 24/137 (17%) Query: 2 ASRSKRRAVESGVPQPPDPPVQRDEEEEKEVENEDE---------------DDDDSDKEK 46 A K E + D + +E++E E E+EDE +D+D + ++ Sbjct: 134 AKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDE 193 Query: 47 DEEDEVIDEEVNIEFEAYSLSDNDYDGIKKLLQQLFLKAPVNTAELTDLLIQQNHIGSVI 106 D+ED+ DEE + E EA + KK + + +KA N AE D Sbjct: 194 DDEDDDDDEEDDSEEEAMETTPAKG---KKAAKVVPVKAK-NVAEDED-----EEEDDED 244 Query: 107 KQTDVSEDSNDDMDEDE 123 + D ED DD DED+ Sbjct: 245 EDDDDDEDDEDDDDEDD 261 Score = 38.1 bits (87), Expect = 0.011 Identities = 17/43 (39%), Positives = 27/43 (62%) Query: 20 PPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFE 62 P ++ E+++ E +DED+DD D E DE+D+ D+E E E Sbjct: 226 PVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEE 268 Score = 37.7 bits (86), Expect = 0.014 Identities = 14/39 (35%), Positives = 28/39 (71%) Query: 19 DPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEV 57 D + D+E+E + ++ED++DDD + +++EE+E +E V Sbjct: 235 DEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPV 273 Score = 36.2 bits (82), Expect = 0.040 Identities = 33/149 (22%), Positives = 52/149 (34%), Gaps = 32/149 (21%) Query: 18 PDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDNDYDGIKKL 77 P + + +KE +E+EDDD + E+D+EDE D D D I+ Sbjct: 130 PAKGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDE----------------DEDEDEIEPA 173 Query: 78 LQQLFLKAPVNTAELTDLLIQQNHIGSVIKQTDVSEDSNDDMDEDEVFGFISLLNLTERK 137 + AP + E + ED DD D++E + T K Sbjct: 174 AMKAAAAAPASEDE----------------DDEDDEDDEDDDDDEEDDSEEEAMETTPAK 217 Query: 138 GTQCVEQIQELVLRFCEKNCEKSMVEQLD 166 G + + + E E+ E D Sbjct: 218 GKKAAKVVPVKAKNVAEDEDEEEDDEDED 246 Score = 32.7 bits (73), Expect = 0.44 Identities = 12/44 (27%), Positives = 28/44 (63%) Query: 6 KRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEE 49 K + V + D + D+++E + +++DEDD++ ++E++EE Sbjct: 228 KAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEE 271 Score = 30.8 bits (68), Expect = 1.7 Identities = 11/42 (26%), Positives = 28/42 (66%) Query: 35 EDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDNDYDGIKK 76 EDED+++ D+++D++D+ DE+ + E + + + + +K+ Sbjct: 234 EDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKE 275 Score = 29.6 bits (65), Expect = 3.8 Identities = 12/26 (46%), Positives = 18/26 (69%) Query: 20 PPVQRDEEEEKEVENEDEDDDDSDKE 45 PP + +E+ E E +EDE+DD S +E Sbjct: 20 PPKEVEEDSEDEEMSEDEEDDSSGEE 45 >gi|113204617 skeletal muscle ryanodine receptor isoform 2 [Homo sapiens] Length = 5033 Score = 43.5 bits (101), Expect = 3e-04 Identities = 22/69 (31%), Positives = 41/69 (59%) Query: 19 DPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDNDYDGIKKLL 78 +P V +EEEE++ E E E++D+ +KE+DEE+ ++E + E + +G+++ L Sbjct: 1867 EPEVFTEEEEEEDEEEEGEEEDEEEKEEDEEETAQEKEDEEKEEEEAAEGEKEEGLEEGL 1926 Query: 79 QQLFLKAPV 87 Q+ L V Sbjct: 1927 LQMKLPESV 1935 Score = 30.0 bits (66), Expect = 2.9 Identities = 14/49 (28%), Positives = 27/49 (55%) Query: 8 RAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEE 56 + +E V + +EE E+E E E E+D++ ++ E++E +EE Sbjct: 1864 KMIEPEVFTEEEEEEDEEEEGEEEDEEEKEEDEEETAQEKEDEEKEEEE 1912 >gi|113204615 skeletal muscle ryanodine receptor isoform 1 [Homo sapiens] Length = 5038 Score = 43.5 bits (101), Expect = 3e-04 Identities = 22/69 (31%), Positives = 41/69 (59%) Query: 19 DPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDNDYDGIKKLL 78 +P V +EEEE++ E E E++D+ +KE+DEE+ ++E + E + +G+++ L Sbjct: 1867 EPEVFTEEEEEEDEEEEGEEEDEEEKEEDEEETAQEKEDEEKEEEEAAEGEKEEGLEEGL 1926 Query: 79 QQLFLKAPV 87 Q+ L V Sbjct: 1927 LQMKLPESV 1935 Score = 30.0 bits (66), Expect = 2.9 Identities = 14/49 (28%), Positives = 27/49 (55%) Query: 8 RAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEE 56 + +E V + +EE E+E E E E+D++ ++ E++E +EE Sbjct: 1864 KMIEPEVFTEEEEEEDEEEEGEEEDEEEKEEDEEETAQEKEDEEKEEEE 1912 >gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4 [Homo sapiens] Length = 2073 Score = 43.5 bits (101), Expect = 3e-04 Identities = 20/54 (37%), Positives = 35/54 (64%) Query: 23 QRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDNDYDGIKK 76 + +EEEE E E E+E++++ D+E++EE+E +EE NI+ L+ IK+ Sbjct: 1070 EEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKR 1123 Score = 37.4 bits (85), Expect = 0.018 Identities = 14/34 (41%), Positives = 27/34 (79%) Query: 23 QRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEE 56 + EEE+E E+E+E++++ ++E+DEE+E +EE Sbjct: 1066 KESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEE 1099 Score = 34.7 bits (78), Expect = 0.12 Identities = 20/66 (30%), Positives = 35/66 (53%) Query: 4 RSKRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEA 63 +SK + + S +P + E KE E+E+++D ++E++EE+E DEE E E Sbjct: 1040 QSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEE 1099 Query: 64 YSLSDN 69 +N Sbjct: 1100 EEEEEN 1105 Score = 33.5 bits (75), Expect = 0.26 Identities = 13/48 (27%), Positives = 31/48 (64%) Query: 22 VQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDN 69 ++ +E +E E E++++++ ++E++EEDE +EE E E ++ + Sbjct: 1062 LELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSS 1109 Score = 33.1 bits (74), Expect = 0.34 Identities = 24/92 (26%), Positives = 42/92 (45%), Gaps = 5/92 (5%) Query: 14 VPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDNDYDG 73 V + PD + E+EE E+ E ED D ++EE+E + N + +A D+ + Sbjct: 1378 VEKDPDG-AKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMES 1436 Query: 74 I----KKLLQQLFLKAPVNTAELTDLLIQQNH 101 ++L ++ F + N DL +Q H Sbjct: 1437 AEVEKEELPRESFKEVLENQETFLDLNVQPGH 1468 Score = 32.0 bits (71), Expect = 0.76 Identities = 25/120 (20%), Positives = 53/120 (44%), Gaps = 10/120 (8%) Query: 4 RSKRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEA 63 + + R E+ P P+ E++ E+E++++ ++E++EE+E +EE E Sbjct: 1321 QEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVE- 1379 Query: 64 YSLSDNDYDGIKKLLQQLFLKAPVNTAELTDLLIQQNHIGSVIKQTDVSEDSNDDMDEDE 123 D DG K ++ P + E D +H + + S + + D D+++ Sbjct: 1380 -----KDPDGAKSQEKE----EPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDED 1430 Score = 30.4 bits (67), Expect = 2.2 Identities = 15/73 (20%), Positives = 38/73 (52%) Query: 3 SRSKRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFE 62 S +K ++ + P PV + + E+ E ++++ +++++EE+E +EE + E E Sbjct: 1035 SPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEE 1094 Query: 63 AYSLSDNDYDGIK 75 + + + I+ Sbjct: 1095 EEEEEEEEEENIQ 1107 >gi|51477718 TATA box binding protein-associated factor, RNA polymerase II, Q [Homo sapiens] Length = 462 Score = 42.4 bits (98), Expect = 6e-04 Identities = 29/115 (25%), Positives = 56/115 (48%), Gaps = 15/115 (13%) Query: 19 DPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEF---EAYSLSDNDYDGIK 75 D D+E+E E E+EDED+D ++E+D +E ++ ++ EF Y ++ + Sbjct: 333 DDDEDEDDEDEDEDEDEDEDEDKEEEEEDCSEEYLERQLQAEFIESGQYRANEGTSSIVM 392 Query: 76 KLLQQLFLKAP-----VNTAELTDLLIQ-------QNHIGSVIKQTDVSEDSNDD 118 ++ +Q+ K N A+ LI +NH SV++Q ++ E ++ Sbjct: 393 EIQKQIEKKEKKLHKIQNKAQRQKDLIMKVENLTLKNHFQSVLEQLELQEKQKNE 447 Score = 37.4 bits (85), Expect = 0.018 Identities = 39/149 (26%), Positives = 75/149 (50%), Gaps = 13/149 (8%) Query: 24 RDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDNDYDGIKKLLQQLFL 83 R+ + N+D++D+D + E ++EDE DE+ E E D + +++ LQ F+ Sbjct: 322 REMFSDSRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEEE-----DCSEEYLERQLQAEFI 376 Query: 84 KAPVNTA-ELTDLLIQQNHIGSVIKQTDVSEDSNDDMDEDEVFGFISLLNLTERKGTQCV 142 ++ A E T ++ + K+ + + N + ++ + + NLT + Q V Sbjct: 377 ESGQYRANEGTSSIVMEIQKQIEKKEKKLHKIQNKAQRQKDL--IMKVENLTLKNHFQSV 434 Query: 143 EQIQELVLRFCEKNCEK--SMVEQLDKFL 169 +++L L+ +KN EK S+ EQL +FL Sbjct: 435 --LEQLELQEKQKN-EKLISLQEQLQRFL 460 >gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 family, member B [Homo sapiens] Length = 251 Score = 42.0 bits (97), Expect = 7e-04 Identities = 24/59 (40%), Positives = 34/59 (57%), Gaps = 11/59 (18%) Query: 25 DEEEEKEVENEDEDDDDSD------KEKDEEDEVI-----DEEVNIEFEAYSLSDNDYD 72 DEEEE E ++ED+DD D E+D+EDE + D+EV+ E E + L + D D Sbjct: 166 DEEEEDEEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDEDDDEVSEEEEEFGLDEEDED 224 Score = 33.5 bits (75), Expect = 0.26 Identities = 21/56 (37%), Positives = 31/56 (55%), Gaps = 4/56 (7%) Query: 11 ESGVPQPPDPPVQRDEEEEKEVENEDED---DDDSDKEKDEEDEV-IDEEVNIEFE 62 E G + + +EEE E ++EDED D+D D+ +EE+E +DEE E E Sbjct: 172 EEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDEDDDEVSEEEEEFGLDEEDEDEDE 227 Score = 33.1 bits (74), Expect = 0.34 Identities = 14/36 (38%), Positives = 28/36 (77%), Gaps = 4/36 (11%) Query: 25 DEEEEKEVENEDEDDDDSDKEK----DEEDEVIDEE 56 +++E+++VE +++DD+ S++E+ DEEDE DE+ Sbjct: 193 EDDEDEDVEGDEDDDEVSEEEEEFGLDEEDEDEDED 228 Score = 31.2 bits (69), Expect = 1.3 Identities = 19/55 (34%), Positives = 29/55 (52%), Gaps = 4/55 (7%) Query: 19 DPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDNDYDG 73 D + E V+ E+ED++ D E+DE+DE +EE EF+ D D +G Sbjct: 152 DQEAPDSDAEVDGVDEEEEDEEGED-EEDEDDEDGEEE---EFDEEDDEDEDVEG 202 Score = 30.8 bits (68), Expect = 1.7 Identities = 15/37 (40%), Positives = 26/37 (70%), Gaps = 5/37 (13%) Query: 19 DPPVQRDEEEEKEVENEDE----DDDDSDKEKDEEDE 51 D V+ DE+++ EV E+E D++D D+++DEE+E Sbjct: 197 DEDVEGDEDDD-EVSEEEEEFGLDEEDEDEDEDEEEE 232 >gi|13654270 LAS1-like [Homo sapiens] Length = 734 Score = 41.6 bits (96), Expect = 0.001 Identities = 21/49 (42%), Positives = 33/49 (67%), Gaps = 5/49 (10%) Query: 22 VQRDEEEEKEV-----ENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYS 65 V+ +E+EEKEV E E+E+DD ++E+DE+DE +EE +E +S Sbjct: 564 VKEEEKEEKEVLPDQVEEEEENDDQEEEEEDEDDEDDEEEDRMEVGPFS 612 Score = 33.9 bits (76), Expect = 0.20 Identities = 14/33 (42%), Positives = 21/33 (63%) Query: 20 PPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEV 52 P +EEE + E E+ED+DD D E+++ EV Sbjct: 576 PDQVEEEEENDDQEEEEEDEDDEDDEEEDRMEV 608 Score = 33.1 bits (74), Expect = 0.34 Identities = 12/28 (42%), Positives = 20/28 (71%) Query: 18 PDPPVQRDEEEEKEVENEDEDDDDSDKE 45 PD + +E +++E E EDEDD+D ++E Sbjct: 576 PDQVEEEEENDDQEEEEEDEDDEDDEEE 603 Score = 30.8 bits (68), Expect = 1.7 Identities = 10/31 (32%), Positives = 21/31 (67%) Query: 14 VPQPPDPPVQRDEEEEKEVENEDEDDDDSDK 44 +P + + D++EE+E + +DEDD++ D+ Sbjct: 575 LPDQVEEEEENDDQEEEEEDEDDEDDEEEDR 605 >gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo sapiens] Length = 1130 Score = 41.2 bits (95), Expect = 0.001 Identities = 17/44 (38%), Positives = 31/44 (70%) Query: 19 DPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFE 62 D + +EEEE+E E E+E+++D ++E+++E+E +EE E E Sbjct: 887 DEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEE 930 Score = 38.1 bits (87), Expect = 0.011 Identities = 15/38 (39%), Positives = 28/38 (73%) Query: 23 QRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIE 60 + +EEEE++ E E+ED+++ +E++EE+E +EE E Sbjct: 901 EEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEE 938 Score = 37.4 bits (85), Expect = 0.018 Identities = 19/54 (35%), Positives = 33/54 (61%), Gaps = 1/54 (1%) Query: 10 VESGVPQPPDPPVQRDEEEEKEVENED-EDDDDSDKEKDEEDEVIDEEVNIEFE 62 + S + + + +EEEE+E E ED E++++ ++E EE+E +EE EFE Sbjct: 883 INSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFE 936 Score = 36.6 bits (83), Expect = 0.031 Identities = 16/51 (31%), Positives = 32/51 (62%) Query: 23 QRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDNDYDG 73 + +EEEE+E E E+E++++ +E++E++E EE E E + + +G Sbjct: 890 EEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEG 940 Score = 35.4 bits (80), Expect = 0.069 Identities = 15/53 (28%), Positives = 30/53 (56%) Query: 10 VESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFE 62 V G P PP ++ + + DE++++ ++E++EE+E +EE + E E Sbjct: 861 VPEGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEE 913 Score = 34.7 bits (78), Expect = 0.12 Identities = 22/79 (27%), Positives = 35/79 (44%), Gaps = 1/79 (1%) Query: 8 RAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLS 67 R ES PP + +E E+E +D SDK + + +EE+ E EA +L Sbjct: 1039 REGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEMETETEAEALQ 1098 Query: 68 DNDYDGIKKLLQQLFLKAP 86 + + D +L F+ P Sbjct: 1099 EKEQDDTAAMLAD-FIDCP 1116 Score = 34.3 bits (77), Expect = 0.15 Identities = 15/36 (41%), Positives = 28/36 (77%), Gaps = 1/36 (2%) Query: 23 QRDEEEEKEVENE-DEDDDDSDKEKDEEDEVIDEEV 57 + +EEEE+E E E +E++ + ++E++EEDE +EE+ Sbjct: 922 EEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEEL 957 Score = 33.1 bits (74), Expect = 0.34 Identities = 16/37 (43%), Positives = 24/37 (64%) Query: 26 EEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFE 62 EEEE+E E +E+ ++ + E +EE+E DEE E E Sbjct: 922 EEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELE 958 Score = 32.7 bits (73), Expect = 0.44 Identities = 13/40 (32%), Positives = 28/40 (70%) Query: 23 QRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFE 62 + +E+EE+ E E+E++++ ++E +EE+ ++EE E E Sbjct: 912 EEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDE 951 Score = 32.0 bits (71), Expect = 0.76 Identities = 13/36 (36%), Positives = 26/36 (72%) Query: 25 DEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIE 60 +EEEE+E E+ ++++ + E++EE+E +EE +E Sbjct: 923 EEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELE 958 Score = 28.5 bits (62), Expect = 8.4 Identities = 11/55 (20%), Positives = 34/55 (61%) Query: 23 QRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDNDYDGIKKL 77 + ++ EE+E + E+ +++ ++E++ E+E +EE +E E + + + ++++ Sbjct: 906 EEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEV 960 >gi|86262149 zinc finger and BTB domain containing 7C [Homo sapiens] Length = 619 Score = 41.2 bits (95), Expect = 0.001 Identities = 17/42 (40%), Positives = 30/42 (71%) Query: 19 DPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIE 60 +P EE++KE +++DEDDDD + E++EE+E D++ + E Sbjct: 128 EPGGDGGEEDDKEDDDDDEDDDDEEDEEEEEEEEEDDDDDTE 169 Score = 38.1 bits (87), Expect = 0.011 Identities = 16/45 (35%), Positives = 31/45 (68%) Query: 25 DEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDN 69 D EE + E++D+D+DD D+E +EE+E +E+ + + E ++ +N Sbjct: 132 DGGEEDDKEDDDDDEDDDDEEDEEEEEEEEEDDDDDTEDFADQEN 176 Score = 33.9 bits (76), Expect = 0.20 Identities = 13/32 (40%), Positives = 23/32 (71%) Query: 25 DEEEEKEVENEDEDDDDSDKEKDEEDEVIDEE 56 DEE+E+E E E+EDDDD ++ +++ + D + Sbjct: 150 DEEDEEEEEEEEEDDDDDTEDFADQENLPDPQ 181 Score = 33.5 bits (75), Expect = 0.26 Identities = 14/35 (40%), Positives = 23/35 (65%) Query: 25 DEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNI 59 D+EE++E E E+E+DDD D E + E + + +I Sbjct: 149 DDEEDEEEEEEEEEDDDDDTEDFADQENLPDPQDI 183 Score = 32.7 bits (73), Expect = 0.44 Identities = 12/41 (29%), Positives = 27/41 (65%) Query: 30 KEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDND 70 +E + ED+DDD+ D ++++E+E +EE + + + +D + Sbjct: 135 EEDDKEDDDDDEDDDDEEDEEEEEEEEEDDDDDTEDFADQE 175 >gi|195546900 suppressor of Ty 5 homolog isoform a [Homo sapiens] Length = 1087 Score = 40.8 bits (94), Expect = 0.002 Identities = 26/104 (25%), Positives = 53/104 (50%), Gaps = 6/104 (5%) Query: 2 ASRSKRRAVESGVPQPPDPPVQRDEEEEKEV-ENEDEDDDDSDKEKDEEDEVIDEEVNIE 60 A + R +G + +P + +EEEE+E E E+E+DDD +K I +E +++ Sbjct: 24 AEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEEEDDDRPPKKPRHGGFILDEADVD 83 Query: 61 FEAYSLSDNDYDGIKKLLQQLFLKAPVNTAELTDLLIQQNHIGS 104 E Y D DG + +L+ K + + + ++++ ++ G+ Sbjct: 84 DE-YEDEDQWEDGAEDILE----KEEIEASNIDNVVLDEDRSGA 122 >gi|161169023 suppressor of Ty 5 homolog isoform a [Homo sapiens] Length = 1087 Score = 40.8 bits (94), Expect = 0.002 Identities = 26/104 (25%), Positives = 53/104 (50%), Gaps = 6/104 (5%) Query: 2 ASRSKRRAVESGVPQPPDPPVQRDEEEEKEV-ENEDEDDDDSDKEKDEEDEVIDEEVNIE 60 A + R +G + +P + +EEEE+E E E+E+DDD +K I +E +++ Sbjct: 24 AEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEEEDDDRPPKKPRHGGFILDEADVD 83 Query: 61 FEAYSLSDNDYDGIKKLLQQLFLKAPVNTAELTDLLIQQNHIGS 104 E Y D DG + +L+ K + + + ++++ ++ G+ Sbjct: 84 DE-YEDEDQWEDGAEDILE----KEEIEASNIDNVVLDEDRSGA 122 >gi|20149524 suppressor of Ty 5 homolog isoform a [Homo sapiens] Length = 1087 Score = 40.8 bits (94), Expect = 0.002 Identities = 26/104 (25%), Positives = 53/104 (50%), Gaps = 6/104 (5%) Query: 2 ASRSKRRAVESGVPQPPDPPVQRDEEEEKEV-ENEDEDDDDSDKEKDEEDEVIDEEVNIE 60 A + R +G + +P + +EEEE+E E E+E+DDD +K I +E +++ Sbjct: 24 AEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEEEDDDRPPKKPRHGGFILDEADVD 83 Query: 61 FEAYSLSDNDYDGIKKLLQQLFLKAPVNTAELTDLLIQQNHIGS 104 E Y D DG + +L+ K + + + ++++ ++ G+ Sbjct: 84 DE-YEDEDQWEDGAEDILE----KEEIEASNIDNVVLDEDRSGA 122 >gi|210032580 SET domain containing 1B [Homo sapiens] Length = 1923 Score = 40.8 bits (94), Expect = 0.002 Identities = 21/48 (43%), Positives = 28/48 (58%), Gaps = 1/48 (2%) Query: 25 DEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDNDYD 72 +EEEE E E E+EDDDD D + +E E DE+ + EA + D D Sbjct: 1049 EEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALS-EASEKDEGDSD 1095 Score = 29.6 bits (65), Expect = 3.8 Identities = 10/34 (29%), Positives = 22/34 (64%) Query: 16 QPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEE 49 +PPD D++ + + DE+D++S++E+D + Sbjct: 968 EPPDTTSSGDQKRLRPSTSVDEEDEESERERDRD 1001 Score = 29.3 bits (64), Expect = 4.9 Identities = 20/49 (40%), Positives = 29/49 (59%), Gaps = 4/49 (8%) Query: 25 DEEEEKEVENEDEDDDDSD-KEKDEEDEVIDEEVNI---EFEAYSLSDN 69 D ++ E EN+DED S+ EKDE D +E V+I + EA S S++ Sbjct: 1067 DSDDRDESENDDEDTALSEASEKDEGDSDEEETVSIVTSKAEATSSSES 1115 >gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens] Length = 4374 Score = 40.4 bits (93), Expect = 0.002 Identities = 22/63 (34%), Positives = 35/63 (55%), Gaps = 2/63 (3%) Query: 18 PDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDNDYDGIKKL 77 P+ + +EE+ NEDEDD ++E++EEDE D+E + E D+D DG + Sbjct: 2409 PEDEEEHTQEEDSSGSNEDEDDSQDEEEEEEEDEEDDQEDDEGEEGD--EDDDDDGSEME 2466 Query: 78 LQQ 80 L + Sbjct: 2467 LDE 2469 Score = 37.0 bits (84), Expect = 0.024 Identities = 19/54 (35%), Positives = 31/54 (57%), Gaps = 2/54 (3%) Query: 19 DPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDNDYD 72 DP + + +E++ +ED+DDS E++EE+E DEE + E + D D D Sbjct: 2408 DPEDEEEHTQEEDSSGSNEDEDDSQDEEEEEEE--DEEDDQEDDEGEEGDEDDD 2459 Score = 36.2 bits (82), Expect = 0.040 Identities = 14/50 (28%), Positives = 32/50 (64%) Query: 12 SGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEF 61 SG + D +EEEE++ E++ EDD+ + ++D++D+ + E++ ++ Sbjct: 2422 SGSNEDEDDSQDEEEEEEEDEEDDQEDDEGEEGDEDDDDDGSEMELDEDY 2471 Score = 35.4 bits (80), Expect = 0.069 Identities = 17/56 (30%), Positives = 32/56 (57%), Gaps = 1/56 (1%) Query: 16 QPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDNDY 71 Q D ++E++ + E E+E++D+ D ++D+E E DE+ + + L D DY Sbjct: 2417 QEEDSSGSNEDEDDSQDEEEEEEEDEEDDQEDDEGEEGDEDDDDDGSEMEL-DEDY 2471 >gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo sapiens] Length = 2168 Score = 40.4 bits (93), Expect = 0.002 Identities = 18/49 (36%), Positives = 33/49 (67%) Query: 25 DEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDNDYDG 73 D K+ E+ +ED+++ D+E+DEED+ DE + + E+ S S++D +G Sbjct: 597 DIPSSKDSEDSNEDEEEDDEEEDEEDDEDDESDDSQSESDSNSESDTEG 645 Score = 38.9 bits (89), Expect = 0.006 Identities = 25/76 (32%), Positives = 37/76 (48%), Gaps = 8/76 (10%) Query: 8 RAVESGVPQPPDPPVQRDEEEEKEVENEDEDD-----DDSDKEKD---EEDEVIDEEVNI 59 R +S +P D ++EEE + E ++EDD DDS E D E D EE + Sbjct: 592 RGTDSDIPSSKDSEDSNEDEEEDDEEEDEEDDEDDESDDSQSESDSNSESDTEGSEEEDD 651 Query: 60 EFEAYSLSDNDYDGIK 75 + + SD+D +G K Sbjct: 652 DDKDQDESDSDTEGEK 667 Score = 32.7 bits (73), Expect = 0.44 Identities = 19/56 (33%), Positives = 30/56 (53%), Gaps = 5/56 (8%) Query: 4 RSKRRAVESGVPQPP---DPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEE 56 R ++ G Q P P ++ + + + +D+DDDDSD + DE+DE DEE Sbjct: 1266 RDTSGGIDLGEEQHPLGTPTPGRKRRRKGGDSDYDDDDDDDSDDQGDEDDE--DEE 1319 Score = 31.6 bits (70), Expect = 0.99 Identities = 19/63 (30%), Positives = 31/63 (49%), Gaps = 6/63 (9%) Query: 13 GVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDNDYD 72 G+ ++ DEEEE + E+ +DDDSD E + + + N + + +SD D Sbjct: 259 GISSSDSDDLEEDEEEEDQ-SIEESEDDDSDSESEAQ-----HKSNNQVLLHGISDPKAD 312 Query: 73 GIK 75 G K Sbjct: 313 GQK 315 Score = 28.5 bits (62), Expect = 8.4 Identities = 13/44 (29%), Positives = 25/44 (56%), Gaps = 2/44 (4%) Query: 13 GVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEE 56 G P P +R + + + +++D+DD D ++D+EDE E+ Sbjct: 1282 GTPTPGRK--RRRKGGDSDYDDDDDDDSDDQGDEDDEDEEDKED 1323 >gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens] Length = 1390 Score = 40.0 bits (92), Expect = 0.003 Identities = 16/33 (48%), Positives = 25/33 (75%) Query: 26 EEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVN 58 E+E+ E +++D+DDDD D ++D+EDE EE N Sbjct: 258 EDEDDEDDDDDDDDDDDDDDEDDEDEEDGEEEN 290 Score = 37.7 bits (86), Expect = 0.014 Identities = 14/32 (43%), Positives = 24/32 (75%) Query: 25 DEEEEKEVENEDEDDDDSDKEKDEEDEVIDEE 56 D+E E + E+ED++DDD D + D++D+ D+E Sbjct: 250 DQEHEDDGEDEDDEDDDDDDDDDDDDDDEDDE 281 Score = 37.4 bits (85), Expect = 0.018 Identities = 14/34 (41%), Positives = 24/34 (70%) Query: 23 QRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEE 56 + E++E E + EDEDD+D D + D++D+ DE+ Sbjct: 246 EEGEDQEHEDDGEDEDDEDDDDDDDDDDDDDDED 279 Score = 37.0 bits (84), Expect = 0.024 Identities = 15/46 (32%), Positives = 28/46 (60%) Query: 11 ESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEE 56 E V + Q E++ ++ ++ED+DDDD D + D++++ DEE Sbjct: 239 EGSVESSEEGEDQEHEDDGEDEDDEDDDDDDDDDDDDDDEDDEDEE 284 Score = 37.0 bits (84), Expect = 0.024 Identities = 13/32 (40%), Positives = 26/32 (81%) Query: 25 DEEEEKEVENEDEDDDDSDKEKDEEDEVIDEE 56 ++E++++ +++D+DDDD D E DE++E +EE Sbjct: 258 EDEDDEDDDDDDDDDDDDDDEDDEDEEDGEEE 289 Score = 35.8 bits (81), Expect = 0.053 Identities = 15/52 (28%), Positives = 32/52 (61%) Query: 11 ESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFE 62 + G + + ++ E++ E E++++DDDD D + D++DE ++E + E E Sbjct: 238 QEGSVESSEEGEDQEHEDDGEDEDDEDDDDDDDDDDDDDDEDDEDEEDGEEE 289 Score = 35.0 bits (79), Expect = 0.090 Identities = 15/45 (33%), Positives = 29/45 (64%) Query: 25 DEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDN 69 +E E++E E++ ED+DD D + D++D+ D++ + E E +N Sbjct: 246 EEGEDQEHEDDGEDEDDEDDDDDDDDDDDDDDEDDEDEEDGEEEN 290 Score = 28.5 bits (62), Expect = 8.4 Identities = 21/85 (24%), Positives = 41/85 (48%), Gaps = 6/85 (7%) Query: 1 MASRSKRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIE 60 M +R K++ + Q D ++E E E ED + D +DE+DE D++ + + Sbjct: 218 MYTRGKQKDI-----QRTDEETTDNQEGSVESSEEGEDQEHEDDGEDEDDEDDDDDDDDD 272 Query: 61 FEAYSLSDND-YDGIKKLLQQLFLK 84 + D D DG ++ ++ +L+ Sbjct: 273 DDDDDEDDEDEEDGEEENQKRYYLR 297 >gi|58331272 zinc finger, CCHC domain containing 6 [Homo sapiens] Length = 1495 Score = 40.0 bits (92), Expect = 0.003 Identities = 39/179 (21%), Positives = 79/179 (44%), Gaps = 20/179 (11%) Query: 25 DEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDNDYDGIKKLLQQLFLK 84 +EEE+ E E E+E+ + ++++ED + +E+ E + D D + + +L Sbjct: 846 EEEEDDEEEEEEEEPRLTINQREDEDGMANED---ELDNTYTGSGDEDALSEEDDELGEA 902 Query: 85 APVNTAELTD------LLIQQNHIGSVIKQTDVSEDSNDDMDEDEVFGFISLLNLTERKG 138 A + LL++ N I +K+ +V E+ N +D+ + F S L T+ K Sbjct: 903 AKYEDVKECGKHVERALLVELNKIS--LKEENVCEEKNSPVDQSDFFYEFSKLIFTKGKS 960 Query: 139 TQCVEQIQELVLRFCEKNCEKSMVEQLDKFLNDTTKPVGLLLSERFINVPPQIALPMYQ 197 V + + E + +K E + + P L+ +F+N+ Q+ + Y+ Sbjct: 961 PTVVCSLCKR-----EGHLKKDCPEDFKRIQLEPLPP----LTPKFLNILDQVCIQCYK 1010 >gi|4503257 death-domain associated protein isoform a [Homo sapiens] Length = 740 Score = 39.7 bits (91), Expect = 0.004 Identities = 23/59 (38%), Positives = 35/59 (59%), Gaps = 4/59 (6%) Query: 23 QRDEEEEKEVENEDEDDDDSDKEKD----EEDEVIDEEVNIEFEAYSLSDNDYDGIKKL 77 + DEEEE+E E E+E+ DS++E+D +E + DEE + E EA + D D + L Sbjct: 442 ESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSL 500 Score = 34.3 bits (77), Expect = 0.15 Identities = 13/24 (54%), Positives = 21/24 (87%) Query: 33 ENEDEDDDDSDKEKDEEDEVIDEE 56 E +DEDD++SD+E++EE+E +EE Sbjct: 434 ETDDEDDEESDEEEEEEEEEEEEE 457 Score = 33.9 bits (76), Expect = 0.20 Identities = 14/49 (28%), Positives = 30/49 (61%) Query: 12 SGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIE 60 SG+ P R E ++++ E DE++++ ++E++EE +EE ++E Sbjct: 420 SGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLE 468 >gi|215422388 death-domain associated protein isoform a [Homo sapiens] Length = 740 Score = 39.7 bits (91), Expect = 0.004 Identities = 23/59 (38%), Positives = 35/59 (59%), Gaps = 4/59 (6%) Query: 23 QRDEEEEKEVENEDEDDDDSDKEKD----EEDEVIDEEVNIEFEAYSLSDNDYDGIKKL 77 + DEEEE+E E E+E+ DS++E+D +E + DEE + E EA + D D + L Sbjct: 442 ESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSL 500 Score = 34.3 bits (77), Expect = 0.15 Identities = 13/24 (54%), Positives = 21/24 (87%) Query: 33 ENEDEDDDDSDKEKDEEDEVIDEE 56 E +DEDD++SD+E++EE+E +EE Sbjct: 434 ETDDEDDEESDEEEEEEEEEEEEE 457 Score = 33.9 bits (76), Expect = 0.20 Identities = 14/49 (28%), Positives = 30/49 (61%) Query: 12 SGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIE 60 SG+ P R E ++++ E DE++++ ++E++EE +EE ++E Sbjct: 420 SGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLE 468 >gi|215422366 death-domain associated protein isoform b [Homo sapiens] Length = 752 Score = 39.7 bits (91), Expect = 0.004 Identities = 23/59 (38%), Positives = 35/59 (59%), Gaps = 4/59 (6%) Query: 23 QRDEEEEKEVENEDEDDDDSDKEKD----EEDEVIDEEVNIEFEAYSLSDNDYDGIKKL 77 + DEEEE+E E E+E+ DS++E+D +E + DEE + E EA + D D + L Sbjct: 454 ESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSL 512 Score = 34.3 bits (77), Expect = 0.15 Identities = 13/24 (54%), Positives = 21/24 (87%) Query: 33 ENEDEDDDDSDKEKDEEDEVIDEE 56 E +DEDD++SD+E++EE+E +EE Sbjct: 446 ETDDEDDEESDEEEEEEEEEEEEE 469 Score = 33.9 bits (76), Expect = 0.20 Identities = 14/49 (28%), Positives = 30/49 (61%) Query: 12 SGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIE 60 SG+ P R E ++++ E DE++++ ++E++EE +EE ++E Sbjct: 432 SGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLE 480 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.312 0.132 0.366 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 13,181,038 Number of Sequences: 37866 Number of extensions: 691275 Number of successful extensions: 17442 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 459 Number of HSP's successfully gapped in prelim test: 189 Number of HSP's that attempted gapping in prelim test: 7189 Number of HSP's gapped (non-prelim): 5020 length of query: 322 length of database: 18,247,518 effective HSP length: 102 effective length of query: 220 effective length of database: 14,385,186 effective search space: 3164740920 effective search space used: 3164740920 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.