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Search of human proteins with 7706541
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7706541 regulator of telomere elongation helicase 1 isoform
1 [Homo sapiens]
(1219 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7706541 regulator of telomere elongation helicase 1 isoform 1... 2466 0.0
gi|91984775 regulator of telomere elongation helicase 1 isoform ... 2465 0.0
gi|100913202 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 iso... 237 6e-62
gi|212549538 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 12 [Ho... 230 7e-60
gi|14042978 BRCA1 interacting protein C-terminal helicase 1 [Hom... 218 3e-56
gi|15834617 excision repair cross-complementing rodent repair de... 202 2e-51
gi|100913204 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 iso... 187 7e-47
gi|132566527 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 iso... 184 4e-46
gi|239755744 PREDICTED: similar to Putative ATP-dependent RNA he... 132 3e-30
gi|195947407 excision repair cross-complementing rodent repair d... 98 5e-20
gi|150417989 cyclin K isoform 1 [Homo sapiens] 42 0.005
gi|112421108 capicua homolog [Homo sapiens] 39 0.030
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] 37 0.11
gi|213972636 tumor protein p53 binding protein 1 isoform 1 [Homo... 36 0.20
gi|213972634 tumor protein p53 binding protein 1 isoform 2 [Homo... 36 0.20
gi|5032189 tumor protein p53 binding protein 1 isoform 3 [Homo s... 36 0.20
gi|13899309 ribosomal protein S6 kinase-like 1 [Homo sapiens] 36 0.20
gi|37693995 Kruppel-like factor 13 [Homo sapiens] 36 0.20
gi|33286446 opioid growth factor receptor [Homo sapiens] 36 0.26
gi|148762940 DVL-binding protein DAPLE [Homo sapiens] 36 0.26
gi|187960109 RNA binding motif protein 28 [Homo sapiens] 35 0.33
gi|148762978 similar to CG15216-PA [Homo sapiens] 35 0.33
gi|215820635 protein phosphatase 1, regulatory subunit 13 like [... 35 0.44
gi|63003907 protein phosphatase 1, regulatory subunit 13 like [H... 35 0.44
gi|13470094 apolipoprotein L5 [Homo sapiens] 35 0.44
gi|61966721 Tctex1 domain containing 4 [Homo sapiens] 35 0.44
gi|209862765 RUN and SH3 domain containing 2 [Homo sapiens] 35 0.57
gi|55741719 RUN and SH3 domain containing 2 [Homo sapiens] 35 0.57
gi|111185957 downstream of tyrosine kinase 7 [Homo sapiens] 34 0.74
gi|109637759 calpastatin isoform f [Homo sapiens] 34 0.74
>gi|7706541 regulator of telomere elongation helicase 1 isoform 1
[Homo sapiens]
Length = 1219
Score = 2466 bits (6392), Expect = 0.0
Identities = 1219/1219 (100%), Positives = 1219/1219 (100%)
Query: 1 MPKIVLNGVTVDFPFQPYKCQQEYMTKVLECLQQKVNGILESPTGTGKTLCLLCTTLAWR 60
MPKIVLNGVTVDFPFQPYKCQQEYMTKVLECLQQKVNGILESPTGTGKTLCLLCTTLAWR
Sbjct: 1 MPKIVLNGVTVDFPFQPYKCQQEYMTKVLECLQQKVNGILESPTGTGKTLCLLCTTLAWR 60
Query: 61 EHLRDGISARKIAERAQGELFPDRALSSWGNAAAAAGDPIACYTDIPKIIYASRTHSQLT 120
EHLRDGISARKIAERAQGELFPDRALSSWGNAAAAAGDPIACYTDIPKIIYASRTHSQLT
Sbjct: 61 EHLRDGISARKIAERAQGELFPDRALSSWGNAAAAAGDPIACYTDIPKIIYASRTHSQLT 120
Query: 121 QVINELRNTSYRPKVCVLGSREQLCIHPEVKKQESNHLQIHLCRKKVASRSCHFYNNVEE 180
QVINELRNTSYRPKVCVLGSREQLCIHPEVKKQESNHLQIHLCRKKVASRSCHFYNNVEE
Sbjct: 121 QVINELRNTSYRPKVCVLGSREQLCIHPEVKKQESNHLQIHLCRKKVASRSCHFYNNVEE 180
Query: 181 KSLEQELASPILDIEDLVKSGSKHRVCPYYLSRNLKQQADIIFMPYNYLLDAKSRRAHNI 240
KSLEQELASPILDIEDLVKSGSKHRVCPYYLSRNLKQQADIIFMPYNYLLDAKSRRAHNI
Sbjct: 181 KSLEQELASPILDIEDLVKSGSKHRVCPYYLSRNLKQQADIIFMPYNYLLDAKSRRAHNI 240
Query: 241 DLKGTVVIFDEAHNVEKMCEESASFDLTPHDLASGLDVIDQVLEEQTKAAQQGEPHPEFS 300
DLKGTVVIFDEAHNVEKMCEESASFDLTPHDLASGLDVIDQVLEEQTKAAQQGEPHPEFS
Sbjct: 241 DLKGTVVIFDEAHNVEKMCEESASFDLTPHDLASGLDVIDQVLEEQTKAAQQGEPHPEFS 300
Query: 301 ADSPSPGLNMELEDIAKLKMILLRLEGAIDAVELPGDDSGVTKPGSYIFELFAEAQITFQ 360
ADSPSPGLNMELEDIAKLKMILLRLEGAIDAVELPGDDSGVTKPGSYIFELFAEAQITFQ
Sbjct: 301 ADSPSPGLNMELEDIAKLKMILLRLEGAIDAVELPGDDSGVTKPGSYIFELFAEAQITFQ 360
Query: 361 TKGCILDSLDQIIQHLAGRAGVFTNTAGLQKLADIIQIVFSVDPSEGSPGSPAGLGALQS 420
TKGCILDSLDQIIQHLAGRAGVFTNTAGLQKLADIIQIVFSVDPSEGSPGSPAGLGALQS
Sbjct: 361 TKGCILDSLDQIIQHLAGRAGVFTNTAGLQKLADIIQIVFSVDPSEGSPGSPAGLGALQS 420
Query: 421 YKVHIHPDAGHRRTAQRSDAWSTTAARKRGKVLSYWCFSPGHSMHELVRQGVRSLILTSG 480
YKVHIHPDAGHRRTAQRSDAWSTTAARKRGKVLSYWCFSPGHSMHELVRQGVRSLILTSG
Sbjct: 421 YKVHIHPDAGHRRTAQRSDAWSTTAARKRGKVLSYWCFSPGHSMHELVRQGVRSLILTSG 480
Query: 481 TLAPVSSFALEMQIPFPVCLENPHIIDKHQIWVGVVPRGPDGAQLSSAFDRRFSEECLSS 540
TLAPVSSFALEMQIPFPVCLENPHIIDKHQIWVGVVPRGPDGAQLSSAFDRRFSEECLSS
Sbjct: 481 TLAPVSSFALEMQIPFPVCLENPHIIDKHQIWVGVVPRGPDGAQLSSAFDRRFSEECLSS 540
Query: 541 LGKALGNIARVVPYGLLIFFPSYPVMEKSLEFWRARDLARKMEALKPLFVEPRSKGSFSE 600
LGKALGNIARVVPYGLLIFFPSYPVMEKSLEFWRARDLARKMEALKPLFVEPRSKGSFSE
Sbjct: 541 LGKALGNIARVVPYGLLIFFPSYPVMEKSLEFWRARDLARKMEALKPLFVEPRSKGSFSE 600
Query: 601 TISAYYARVAAPGSTGATFLAVCRGKASEGLDFSDTNGRGVIVTGLPYPPRMDPRVVLKM 660
TISAYYARVAAPGSTGATFLAVCRGKASEGLDFSDTNGRGVIVTGLPYPPRMDPRVVLKM
Sbjct: 601 TISAYYARVAAPGSTGATFLAVCRGKASEGLDFSDTNGRGVIVTGLPYPPRMDPRVVLKM 660
Query: 661 QFLDEMKGQGGAGGQFLSGQEWYRQQASRAVNQAIGRVIRHRQDYGAVFLCDHRFAFADA 720
QFLDEMKGQGGAGGQFLSGQEWYRQQASRAVNQAIGRVIRHRQDYGAVFLCDHRFAFADA
Sbjct: 661 QFLDEMKGQGGAGGQFLSGQEWYRQQASRAVNQAIGRVIRHRQDYGAVFLCDHRFAFADA 720
Query: 721 RAQLPSWVRPHVRVYDNFGHVIRDVAQFFRVAERTMPAPAPRATAPSVRGEDAVSEAKSP 780
RAQLPSWVRPHVRVYDNFGHVIRDVAQFFRVAERTMPAPAPRATAPSVRGEDAVSEAKSP
Sbjct: 721 RAQLPSWVRPHVRVYDNFGHVIRDVAQFFRVAERTMPAPAPRATAPSVRGEDAVSEAKSP 780
Query: 781 GPFFSTRKAKSLDLHVPSLKQRSSGSPAAGDPESSLCVEYEQEPVPARQRPRGLLAALEH 840
GPFFSTRKAKSLDLHVPSLKQRSSGSPAAGDPESSLCVEYEQEPVPARQRPRGLLAALEH
Sbjct: 781 GPFFSTRKAKSLDLHVPSLKQRSSGSPAAGDPESSLCVEYEQEPVPARQRPRGLLAALEH 840
Query: 841 SEQRAGSPGEEQAHSCSTLSLLSEKRPAEEPRGGRKKIRLVSHPEEPVAGAQTDRAKLFM 900
SEQRAGSPGEEQAHSCSTLSLLSEKRPAEEPRGGRKKIRLVSHPEEPVAGAQTDRAKLFM
Sbjct: 841 SEQRAGSPGEEQAHSCSTLSLLSEKRPAEEPRGGRKKIRLVSHPEEPVAGAQTDRAKLFM 900
Query: 901 VAVKQELSQANFATFTQALQDYKGSDDFAALAACLGPLFAEDPKKHNLLQGFYQFVRPHH 960
VAVKQELSQANFATFTQALQDYKGSDDFAALAACLGPLFAEDPKKHNLLQGFYQFVRPHH
Sbjct: 901 VAVKQELSQANFATFTQALQDYKGSDDFAALAACLGPLFAEDPKKHNLLQGFYQFVRPHH 960
Query: 961 KQQFEEVCIQLTGRGCGYRPEHSIPRRQRAQPVLDPTGRTAPDPKLTVSTAAAQQLDPQE 1020
KQQFEEVCIQLTGRGCGYRPEHSIPRRQRAQPVLDPTGRTAPDPKLTVSTAAAQQLDPQE
Sbjct: 961 KQQFEEVCIQLTGRGCGYRPEHSIPRRQRAQPVLDPTGRTAPDPKLTVSTAAAQQLDPQE 1020
Query: 1021 HLNQGRPHLSPRPPPTGDPGSQPQWGSGVPRAGKQGQHAVSAYLADARRALGSAGCSQLL 1080
HLNQGRPHLSPRPPPTGDPGSQPQWGSGVPRAGKQGQHAVSAYLADARRALGSAGCSQLL
Sbjct: 1021 HLNQGRPHLSPRPPPTGDPGSQPQWGSGVPRAGKQGQHAVSAYLADARRALGSAGCSQLL 1080
Query: 1081 AALTAYKQDDDLDKVLAVLAALTTAKPEDFPLLHRFSMFVRPHHKQRFSQTCTDLTGRPY 1140
AALTAYKQDDDLDKVLAVLAALTTAKPEDFPLLHRFSMFVRPHHKQRFSQTCTDLTGRPY
Sbjct: 1081 AALTAYKQDDDLDKVLAVLAALTTAKPEDFPLLHRFSMFVRPHHKQRFSQTCTDLTGRPY 1140
Query: 1141 PGMEPPGPQEERLAVPPVLTHRAPQPGPSRSEKTGKTQSKISSFLRQRPAGTVGAGGEDA 1200
PGMEPPGPQEERLAVPPVLTHRAPQPGPSRSEKTGKTQSKISSFLRQRPAGTVGAGGEDA
Sbjct: 1141 PGMEPPGPQEERLAVPPVLTHRAPQPGPSRSEKTGKTQSKISSFLRQRPAGTVGAGGEDA 1200
Query: 1201 GPSQSSGPPHGPAASEWGL 1219
GPSQSSGPPHGPAASEWGL
Sbjct: 1201 GPSQSSGPPHGPAASEWGL 1219
>gi|91984775 regulator of telomere elongation helicase 1 isoform 2
[Homo sapiens]
Length = 1300
Score = 2465 bits (6388), Expect = 0.0
Identities = 1218/1218 (100%), Positives = 1218/1218 (100%)
Query: 1 MPKIVLNGVTVDFPFQPYKCQQEYMTKVLECLQQKVNGILESPTGTGKTLCLLCTTLAWR 60
MPKIVLNGVTVDFPFQPYKCQQEYMTKVLECLQQKVNGILESPTGTGKTLCLLCTTLAWR
Sbjct: 1 MPKIVLNGVTVDFPFQPYKCQQEYMTKVLECLQQKVNGILESPTGTGKTLCLLCTTLAWR 60
Query: 61 EHLRDGISARKIAERAQGELFPDRALSSWGNAAAAAGDPIACYTDIPKIIYASRTHSQLT 120
EHLRDGISARKIAERAQGELFPDRALSSWGNAAAAAGDPIACYTDIPKIIYASRTHSQLT
Sbjct: 61 EHLRDGISARKIAERAQGELFPDRALSSWGNAAAAAGDPIACYTDIPKIIYASRTHSQLT 120
Query: 121 QVINELRNTSYRPKVCVLGSREQLCIHPEVKKQESNHLQIHLCRKKVASRSCHFYNNVEE 180
QVINELRNTSYRPKVCVLGSREQLCIHPEVKKQESNHLQIHLCRKKVASRSCHFYNNVEE
Sbjct: 121 QVINELRNTSYRPKVCVLGSREQLCIHPEVKKQESNHLQIHLCRKKVASRSCHFYNNVEE 180
Query: 181 KSLEQELASPILDIEDLVKSGSKHRVCPYYLSRNLKQQADIIFMPYNYLLDAKSRRAHNI 240
KSLEQELASPILDIEDLVKSGSKHRVCPYYLSRNLKQQADIIFMPYNYLLDAKSRRAHNI
Sbjct: 181 KSLEQELASPILDIEDLVKSGSKHRVCPYYLSRNLKQQADIIFMPYNYLLDAKSRRAHNI 240
Query: 241 DLKGTVVIFDEAHNVEKMCEESASFDLTPHDLASGLDVIDQVLEEQTKAAQQGEPHPEFS 300
DLKGTVVIFDEAHNVEKMCEESASFDLTPHDLASGLDVIDQVLEEQTKAAQQGEPHPEFS
Sbjct: 241 DLKGTVVIFDEAHNVEKMCEESASFDLTPHDLASGLDVIDQVLEEQTKAAQQGEPHPEFS 300
Query: 301 ADSPSPGLNMELEDIAKLKMILLRLEGAIDAVELPGDDSGVTKPGSYIFELFAEAQITFQ 360
ADSPSPGLNMELEDIAKLKMILLRLEGAIDAVELPGDDSGVTKPGSYIFELFAEAQITFQ
Sbjct: 301 ADSPSPGLNMELEDIAKLKMILLRLEGAIDAVELPGDDSGVTKPGSYIFELFAEAQITFQ 360
Query: 361 TKGCILDSLDQIIQHLAGRAGVFTNTAGLQKLADIIQIVFSVDPSEGSPGSPAGLGALQS 420
TKGCILDSLDQIIQHLAGRAGVFTNTAGLQKLADIIQIVFSVDPSEGSPGSPAGLGALQS
Sbjct: 361 TKGCILDSLDQIIQHLAGRAGVFTNTAGLQKLADIIQIVFSVDPSEGSPGSPAGLGALQS 420
Query: 421 YKVHIHPDAGHRRTAQRSDAWSTTAARKRGKVLSYWCFSPGHSMHELVRQGVRSLILTSG 480
YKVHIHPDAGHRRTAQRSDAWSTTAARKRGKVLSYWCFSPGHSMHELVRQGVRSLILTSG
Sbjct: 421 YKVHIHPDAGHRRTAQRSDAWSTTAARKRGKVLSYWCFSPGHSMHELVRQGVRSLILTSG 480
Query: 481 TLAPVSSFALEMQIPFPVCLENPHIIDKHQIWVGVVPRGPDGAQLSSAFDRRFSEECLSS 540
TLAPVSSFALEMQIPFPVCLENPHIIDKHQIWVGVVPRGPDGAQLSSAFDRRFSEECLSS
Sbjct: 481 TLAPVSSFALEMQIPFPVCLENPHIIDKHQIWVGVVPRGPDGAQLSSAFDRRFSEECLSS 540
Query: 541 LGKALGNIARVVPYGLLIFFPSYPVMEKSLEFWRARDLARKMEALKPLFVEPRSKGSFSE 600
LGKALGNIARVVPYGLLIFFPSYPVMEKSLEFWRARDLARKMEALKPLFVEPRSKGSFSE
Sbjct: 541 LGKALGNIARVVPYGLLIFFPSYPVMEKSLEFWRARDLARKMEALKPLFVEPRSKGSFSE 600
Query: 601 TISAYYARVAAPGSTGATFLAVCRGKASEGLDFSDTNGRGVIVTGLPYPPRMDPRVVLKM 660
TISAYYARVAAPGSTGATFLAVCRGKASEGLDFSDTNGRGVIVTGLPYPPRMDPRVVLKM
Sbjct: 601 TISAYYARVAAPGSTGATFLAVCRGKASEGLDFSDTNGRGVIVTGLPYPPRMDPRVVLKM 660
Query: 661 QFLDEMKGQGGAGGQFLSGQEWYRQQASRAVNQAIGRVIRHRQDYGAVFLCDHRFAFADA 720
QFLDEMKGQGGAGGQFLSGQEWYRQQASRAVNQAIGRVIRHRQDYGAVFLCDHRFAFADA
Sbjct: 661 QFLDEMKGQGGAGGQFLSGQEWYRQQASRAVNQAIGRVIRHRQDYGAVFLCDHRFAFADA 720
Query: 721 RAQLPSWVRPHVRVYDNFGHVIRDVAQFFRVAERTMPAPAPRATAPSVRGEDAVSEAKSP 780
RAQLPSWVRPHVRVYDNFGHVIRDVAQFFRVAERTMPAPAPRATAPSVRGEDAVSEAKSP
Sbjct: 721 RAQLPSWVRPHVRVYDNFGHVIRDVAQFFRVAERTMPAPAPRATAPSVRGEDAVSEAKSP 780
Query: 781 GPFFSTRKAKSLDLHVPSLKQRSSGSPAAGDPESSLCVEYEQEPVPARQRPRGLLAALEH 840
GPFFSTRKAKSLDLHVPSLKQRSSGSPAAGDPESSLCVEYEQEPVPARQRPRGLLAALEH
Sbjct: 781 GPFFSTRKAKSLDLHVPSLKQRSSGSPAAGDPESSLCVEYEQEPVPARQRPRGLLAALEH 840
Query: 841 SEQRAGSPGEEQAHSCSTLSLLSEKRPAEEPRGGRKKIRLVSHPEEPVAGAQTDRAKLFM 900
SEQRAGSPGEEQAHSCSTLSLLSEKRPAEEPRGGRKKIRLVSHPEEPVAGAQTDRAKLFM
Sbjct: 841 SEQRAGSPGEEQAHSCSTLSLLSEKRPAEEPRGGRKKIRLVSHPEEPVAGAQTDRAKLFM 900
Query: 901 VAVKQELSQANFATFTQALQDYKGSDDFAALAACLGPLFAEDPKKHNLLQGFYQFVRPHH 960
VAVKQELSQANFATFTQALQDYKGSDDFAALAACLGPLFAEDPKKHNLLQGFYQFVRPHH
Sbjct: 901 VAVKQELSQANFATFTQALQDYKGSDDFAALAACLGPLFAEDPKKHNLLQGFYQFVRPHH 960
Query: 961 KQQFEEVCIQLTGRGCGYRPEHSIPRRQRAQPVLDPTGRTAPDPKLTVSTAAAQQLDPQE 1020
KQQFEEVCIQLTGRGCGYRPEHSIPRRQRAQPVLDPTGRTAPDPKLTVSTAAAQQLDPQE
Sbjct: 961 KQQFEEVCIQLTGRGCGYRPEHSIPRRQRAQPVLDPTGRTAPDPKLTVSTAAAQQLDPQE 1020
Query: 1021 HLNQGRPHLSPRPPPTGDPGSQPQWGSGVPRAGKQGQHAVSAYLADARRALGSAGCSQLL 1080
HLNQGRPHLSPRPPPTGDPGSQPQWGSGVPRAGKQGQHAVSAYLADARRALGSAGCSQLL
Sbjct: 1021 HLNQGRPHLSPRPPPTGDPGSQPQWGSGVPRAGKQGQHAVSAYLADARRALGSAGCSQLL 1080
Query: 1081 AALTAYKQDDDLDKVLAVLAALTTAKPEDFPLLHRFSMFVRPHHKQRFSQTCTDLTGRPY 1140
AALTAYKQDDDLDKVLAVLAALTTAKPEDFPLLHRFSMFVRPHHKQRFSQTCTDLTGRPY
Sbjct: 1081 AALTAYKQDDDLDKVLAVLAALTTAKPEDFPLLHRFSMFVRPHHKQRFSQTCTDLTGRPY 1140
Query: 1141 PGMEPPGPQEERLAVPPVLTHRAPQPGPSRSEKTGKTQSKISSFLRQRPAGTVGAGGEDA 1200
PGMEPPGPQEERLAVPPVLTHRAPQPGPSRSEKTGKTQSKISSFLRQRPAGTVGAGGEDA
Sbjct: 1141 PGMEPPGPQEERLAVPPVLTHRAPQPGPSRSEKTGKTQSKISSFLRQRPAGTVGAGGEDA 1200
Query: 1201 GPSQSSGPPHGPAASEWG 1218
GPSQSSGPPHGPAASEWG
Sbjct: 1201 GPSQSSGPPHGPAASEWG 1218
>gi|100913202 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11
isoform 1 [Homo sapiens]
Length = 906
Score = 237 bits (604), Expect = 6e-62
Identities = 192/701 (27%), Positives = 315/701 (44%), Gaps = 82/701 (11%)
Query: 106 IPKIIYASRTHSQLTQVINELRNTSYRPKVCV--LGSREQLCIHPEVKKQESNHLQIHLC 163
I KI Y SRTHSQL Q ++E++ + + V + LGSR+ LC++ +VK S L C
Sbjct: 226 ITKIYYCSRTHSQLAQFVHEVKKSPFGKDVRLVSLGSRQNLCVNEDVKSLGSVQLINDRC 285
Query: 164 ---------------------RKKVASRSCHFYNNVEEKSLEQELASPILDIEDLVKSGS 202
R++ +C FYN+ + L E + + D+E L+ G
Sbjct: 286 VDMQRSRHEKKKGAEEEKPKRRRQEKQAACPFYNHEQMGLLRDEALAEVKDMEQLLALGK 345
Query: 203 KHRVCPYYLSRNLKQQADIIFMPYNYLLDAKSRRAHNIDLKGTVVIFDEAHNVEKMCEES 262
+ R CPYY SR A ++ +PY LL A +R+A I L+ VVI DEAHN+
Sbjct: 346 EARACPYYGSRLAIPAAQLVVLPYQMLLHAATRQAAGIRLQDQVVIIDEAHNL------- 398
Query: 263 ASFDLTPHDLASGLDVIDQVLEEQTKAAQQGEPHPEFSADSPSPGLNMELEDIAKLKMIL 322
+D I + + +Q + H + G ++ +++ LK IL
Sbjct: 399 -------------IDTITGMHSVEVSGSQLCQAHSQLLQYVERYGKRLKAKNLMYLKQIL 445
Query: 323 LRLEGAIDA----VELPGDDSGVTKPGS-------YIFELFAEAQITFQTKG-CILDSLD 370
LE + ++ + +++ G+ ++F+ + F+ + C +
Sbjct: 446 YLLEKFVAVLGGNIKQNPNTQSLSQTGTELKTINDFLFQSQIDNINLFKVQRYCEKSMIS 505
Query: 371 QIIQHLAGRAGVFTNTAGLQKLADIIQIVFSVDPSE----GSPGSPAGLGALQ--SYKVH 424
+ + R G ++ KLA Q + S+ P +P + L+ S +H
Sbjct: 506 RKLFGFTERYGAVFSSREQPKLAGFQQFLQSLQPRTTEALAAPADESQASTLRPASPLMH 565
Query: 425 IHPDAGHRRTAQRSDAWSTTAARKRGKV----LSYWCFSPGHSMHELVRQGVRSLILTSG 480
I TA + ++G + L + +P ++V++ R++++ G
Sbjct: 566 IQGFLAALTTANQD---GRVILSRQGSLSQSTLKFLLLNPAVHFAQVVKE-CRAVVIAGG 621
Query: 481 TLAPVSSFALEMQIPFPVCLENP------HIIDKHQIWVGVVPRGPDGAQLSSAFDRRFS 534
T+ PVS F ++ V E H+I I V+ G L F +R
Sbjct: 622 TMQPVSDFRQQLLACAGVEAERVVEFSCGHVIPPDNILPLVICSGISNQPLEFTFQKREL 681
Query: 535 EECLSSLGKALGNIARVVPYGLLIFFPSYPVMEKSLEFWRARDLARKMEALKPLFVEPRS 594
+ + +G+ L N+ VVP G++ FFPSY + + W L ++ A K +F EP+S
Sbjct: 682 PQMMDEVGRILCNLCGVVPGGVVCFFPSYEYLRQVHAHWEKGGLLGRLAARKKIFQEPKS 741
Query: 595 KGSFSETISAYYARVAAPGS-----TGATFLAVCRGKASEGLDFSDTNGRGVIVTGLPYP 649
+ + AY + A G TGA L+V GK SEG++FSD GR V++ G+P+P
Sbjct: 742 AHQVEQVLLAYSRCIQACGQERGQVTGALLLSVVGGKMSEGINFSDNLGRCVVMVGMPFP 801
Query: 650 PRMDPRVVLKMQFLDEMKGQGGAGGQFLSGQEWYRQQASRAVNQAIGRVIRHRQDYGAVF 709
+ KM +LD+ + A GQ G+ +AVNQ+IGR IRH++D+ +V
Sbjct: 802 NIRSAELQEKMAYLDQTLPR--APGQAPPGKALVENLCMKAVNQSIGRAIRHQKDFASVV 859
Query: 710 LCDHRFAFADARAQLPSWVRPHVRVYDNFGHVIRDVAQFFR 750
L D R+A A+LP+W+R V V FG I V +F R
Sbjct: 860 LLDQRYARPPVLAKLPAWIRARVEVKATFGPAIAAVQKFHR 900
Score = 57.4 bits (137), Expect = 8e-08
Identities = 35/94 (37%), Positives = 49/94 (52%), Gaps = 10/94 (10%)
Query: 13 FPFQPYKCQQEYMTKVLECLQQKVNGILESPTGTGKTLCLLCTTLAWREHLRDGISAR-- 70
FPF PY Q+++M ++ L+ GI ESPTGTGK+L L+C L+W LRD +
Sbjct: 15 FPFTPYSIQEDFMAELYRVLEAGKIGIFESPTGTGKSLSLICGALSW---LRDFEQKKRE 71
Query: 71 ---KIAERAQGELF--PDRALSSWGNAAAAAGDP 99
++ E G L D +L + AAG P
Sbjct: 72 EEARLLETGTGPLHDEKDESLCLSSSCEGAAGTP 105
>gi|212549538 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 12 [Homo
sapiens]
Length = 906
Score = 230 bits (586), Expect = 7e-60
Identities = 187/701 (26%), Positives = 314/701 (44%), Gaps = 82/701 (11%)
Query: 106 IPKIIYASRTHSQLTQVINELRNTSYRPKVCV--LGSREQLCIHPEVKKQESNHLQIHLC 163
I KI + SRTHSQL Q ++E++ + + V + LGSR+ LC++ +V+ S L + C
Sbjct: 226 ITKIYHCSRTHSQLAQFVHEVKKSPFGKDVRLVSLGSRQNLCVNEDVRSLGSVQLINNRC 285
Query: 164 ---------------------RKKVASRSCHFYNNVEEKSLEQELASPILDIEDLVKSGS 202
R++ +C FYN+ + L E + + D+E L+ G
Sbjct: 286 VDMQRSRHEKKKGAEEEKPKRRRQEKQAACPFYNHEQMGLLRDEALAEVKDMEQLLALGK 345
Query: 203 KHRVCPYYLSRNLKQQADIIFMPYNYLLDAKSRRAHNIDLKGTVVIFDEAHNVEKMCEES 262
+ R CPYY SR A ++ +PY LL A +R+A I L+ VVI DEAHN+
Sbjct: 346 EARACPYYGSRLAIPAAQLVVLPYQMLLHAATRQAAGIRLQDQVVIIDEAHNL------- 398
Query: 263 ASFDLTPHDLASGLDVIDQVLEEQTKAAQQGEPHPEFSADSPSPGLNMELEDIAKLKMIL 322
+D + + +Q + H + G ++ +++ LK IL
Sbjct: 399 -------------IDTTTSMHSVEVSGSQLCQAHSQLLQYMERYGKRLKAKNLMYLKQIL 445
Query: 323 LRLEGAIDA----VELPGDDSGVTKPG-------SYIFELFAEAQITFQTKG-CILDSLD 370
LE + ++ + +++ G ++F+ + F+ + C +
Sbjct: 446 YLLEKFVAVLGGNIKQNPNTQSLSQTGMELKTINDFLFQSQIDNINLFKVQRYCEKSMIS 505
Query: 371 QIIQHLAGRAGVFTNTAGLQKLADIIQIVFSVDP------SEGSPGSPAGLGALQSYKVH 424
+ + R G ++ KLA Q + S+ P + + S A + S +H
Sbjct: 506 RKLFGFTERYGAVFSSREQPKLAGFQQFLQSLQPRTTEALAAPADESQASVPQPASPLMH 565
Query: 425 IHPDAGHRRTAQRSDAWSTTAARKRGKV----LSYWCFSPGHSMHELVRQGVRSLILTSG 480
I TA + ++G + L + +P ++V++ R++++ G
Sbjct: 566 IEGFLAALTTANQD---GRVILSRQGSLSQSTLKFLLLNPAVHFAQVVKE-CRAVVIAGG 621
Query: 481 TLAPVSSFALEMQIPFPVCLENP------HIIDKHQIWVGVVPRGPDGAQLSSAFDRRFS 534
T+ PVS+F ++ V E H+I I V+ G L F +R
Sbjct: 622 TMQPVSNFRQQLLACAGVEAERVVEFSCGHVIPPDNILPLVICSGVSNQPLEFTFQKRDL 681
Query: 535 EECLSSLGKALGNIARVVPYGLLIFFPSYPVMEKSLEFWRARDLARKMEALKPLFVEPRS 594
+ + +G+ L N+ VV G++ FFPSY + + W L ++ A K +F EP+S
Sbjct: 682 PQMMDEVGRILCNLCGVVSGGVVCFFPSYEYLRQVHAHWEKGGLLGRLAARKKIFQEPKS 741
Query: 595 KGSFSETISAYYARVAAPGS-----TGATFLAVCRGKASEGLDFSDTNGRGVIVTGLPYP 649
+ + AY + A G TGA L+V GK SEG++FSD GR V++ G+P+P
Sbjct: 742 AHQVEQVLLAYSRCLQACGQERGPVTGALLLSVVGGKMSEGINFSDNLGRCVVMVGMPFP 801
Query: 650 PRMDPRVVLKMQFLDEMKGQGGAGGQFLSGQEWYRQQASRAVNQAIGRVIRHRQDYGAVF 709
+ KM +LD+ + A GQ G+ +AVNQ+IGR IRH++D+ ++
Sbjct: 802 NIRSAELQEKMAYLDQTLPR--APGQAHPGKALVENLCMKAVNQSIGRAIRHQKDFASIV 859
Query: 710 LCDHRFAFADARAQLPSWVRPHVRVYDNFGHVIRDVAQFFR 750
L D R+A A+LP+W+R V V FG I V +F R
Sbjct: 860 LLDQRYARPPVLAKLPAWIRARVEVKATFGPAIAAVQKFHR 900
Score = 57.4 bits (137), Expect = 8e-08
Identities = 35/94 (37%), Positives = 49/94 (52%), Gaps = 10/94 (10%)
Query: 13 FPFQPYKCQQEYMTKVLECLQQKVNGILESPTGTGKTLCLLCTTLAWREHLRDGISAR-- 70
FPF PY Q+++M ++ L+ GI ESPTGTGK+L L+C L+W LRD +
Sbjct: 15 FPFTPYSIQEDFMAELYRVLEAGKIGIFESPTGTGKSLSLICGALSW---LRDFEQKKRE 71
Query: 71 ---KIAERAQGELF--PDRALSSWGNAAAAAGDP 99
++ E G L D +L + AAG P
Sbjct: 72 EEARLLETGTGPLHDEKDESLCLSSSCEGAAGTP 105
>gi|14042978 BRCA1 interacting protein C-terminal helicase 1 [Homo
sapiens]
Length = 1249
Score = 218 bits (555), Expect = 3e-56
Identities = 119/310 (38%), Positives = 177/310 (57%), Gaps = 10/310 (3%)
Query: 452 VLSYWCFSPGHSMHELVRQGVRSLILTSGTLAPVSSFALEMQIPFPVCLENPHIIDKHQI 511
VL++WC +P + + + V++++LTSGTL+P+ SF+ E+ + F + LE HII Q+
Sbjct: 588 VLNFWCLNPAVAFSD-INGKVQTIVLTSGTLSPMKSFSSELGVTFTIQLEANHIIKNSQV 646
Query: 512 WVGVVPRGPDGAQLSSAFDRRFSEECLSSLGKALGNIARVVPYGLLIFFPSYPVMEKSLE 571
WVG + GP G L + F + E +G L ++ + V G+L F PSY ++EK E
Sbjct: 647 WVGTIGSGPKGRNLCATFQNTETFEFQDEVGALLLSVCQTVSQGILCFLPSYKLLEKLKE 706
Query: 572 FWRARDLARKMEALKPLFVEPR--SKGSFSETISAYYARVAAPG-STGATFLAVCRGKAS 628
W + L +E +K + VEP+ K +F E + YY + G GA +AVCRGK S
Sbjct: 707 RWLSTGLWHNLELVKTVIVEPQGGEKTNFDELLQVYYDAIKYKGEKDGALLVAVCRGKVS 766
Query: 629 EGLDFSDTNGRGVIVTGLPYPPRMDPRVVLKMQFLDEMKGQGGAGGQFLSGQEWYRQQAS 688
EGLDFSD N R VI G+P+P D +V LK Q+ D G L G++WY QA
Sbjct: 767 EGLDFSDDNARAVITIGIPFPNVKDLQVELKRQYNDHHSKLRG----LLPGRQWYEIQAY 822
Query: 689 RAVNQAIGRVIRHRQDYGAVFLCDHRFAFADAR--AQLPSWVRPHVRVYDNFGHVIRDVA 746
RA+NQA+GR IRHR D+GA+ L D RF +R + L WVR ++ + F + +A
Sbjct: 823 RALNQALGRCIRHRNDWGALILVDDRFRNNPSRYISGLSKWVRQQIQHHSTFESALESLA 882
Query: 747 QFFRVAERTM 756
+F + ++ +
Sbjct: 883 EFSKKHQKVL 892
Score = 140 bits (352), Expect = 1e-32
Identities = 76/189 (40%), Positives = 109/189 (57%), Gaps = 6/189 (3%)
Query: 106 IPKIIYASRTHSQLTQVINELRNTSYRP-KVCVLGSREQLCIHPEVKKQESNHLQIHLCR 164
IPKI + +RTH Q+ Q+ ELR T+Y + +L SR+ C+HPEV + + +
Sbjct: 243 IPKIYFGTRTHKQIAQITRELRRTAYSGVPMTILSSRDHTCVHPEVVGNFNRNEKCMELL 302
Query: 165 KKVASRSCHFYNNVEEKSLEQELAS-----PILDIEDLVKSGSKHRVCPYYLSRNLKQQA 219
+SC+FY+ V + S + L + DIE+LV G K + CPYY +R L Q A
Sbjct: 303 DGKNGKSCYFYHGVHKISDQHTLQTFQGMCKAWDIEELVSLGKKLKACPYYTARELIQDA 362
Query: 220 DIIFMPYNYLLDAKSRRAHNIDLKGTVVIFDEAHNVEKMCEESASFDLTPHDLASGLDVI 279
DIIF PYNYLLDA+ R + +++LK VVI DEAHN+E ESAS+ +T L D +
Sbjct: 363 DIIFCPYNYLLDAQIRESMDLNLKEQVVILDEAHNIEDCARESASYSVTEVQLRFARDEL 422
Query: 280 DQVLEEQTK 288
D ++ +
Sbjct: 423 DSMVNNNIR 431
Score = 62.4 bits (150), Expect = 3e-09
Identities = 29/75 (38%), Positives = 47/75 (62%)
Query: 6 LNGVTVDFPFQPYKCQQEYMTKVLECLQQKVNGILESPTGTGKTLCLLCTTLAWREHLRD 65
+ GV + FP++ Y Q M +L L K + +LESPTG+GK+L LLC+ LAW++ L
Sbjct: 10 IGGVKIYFPYKAYPSQLAMMNSILRGLNSKQHCLLESPTGSGKSLALLCSALAWQQSLSG 69
Query: 66 GISARKIAERAQGEL 80
+ ++E+A+ +L
Sbjct: 70 KPADEGVSEKAEVQL 84
>gi|15834617 excision repair cross-complementing rodent repair
deficiency, complementation group 2 protein isoform 1
[Homo sapiens]
Length = 760
Score = 202 bits (514), Expect = 2e-51
Identities = 197/775 (25%), Positives = 325/775 (41%), Gaps = 120/775 (15%)
Query: 3 KIVLNGVTVDFPFQP-YKCQQEYMTKVLECLQQKVNGILESPTGTGKTLCLLCTTLAWRE 61
K+ ++G+ V FP+ Y Q YM ++ L K +G+LE P+GTGKT+ LL +A++
Sbjct: 2 KLNVDGLLVYFPYDYIYPEQFSYMRELKRTLDAKGHGVLEMPSGTGKTVSLLALIMAYQR 61
Query: 62 HLRDGISARKIAERAQGELFPDRALSSWGNAAAAAGDPIACYTDIPKIIYASRTHSQLTQ 121
A ++ K+IY SRT ++ +
Sbjct: 62 ---------------------------------------AYPLEVTKLIYCSRTVPEIEK 82
Query: 122 VINELRNT------SYRPKVCVLG----SREQLCIHPEVKKQESNHLQIHLCRKKVASR- 170
VI ELR K+ LG SR+ LCIHPEV C AS
Sbjct: 83 VIEELRKLLNFYEKQEGEKLPFLGLALSSRKNLCIHPEVTPLRFGKDVDGKCHSLTASYV 142
Query: 171 -----------SCHFYNNVEEKSLEQELASPILDIEDLVKSGSKHRVCPYYLSRNLKQQA 219
C FY + E L + I +++DL G + CPY+L+R A
Sbjct: 143 RAQYQHDTSLPHCRFYEEFDAHGREVPLPAGIYNLDDLKALGRRQGWCPYFLARYSILHA 202
Query: 220 DIIFMPYNYLLDAKSRRAHNIDL-KGTVVIFDEAHNVEKMCEESASFDLTPHDLASGLDV 278
+++ Y+YLLD K + +L + VV+FDEAHN++ +C +S S +LT L
Sbjct: 203 NVVVYSYHYLLDPKIADLVSKELARKAVVVFDEAHNIDNVCIDSMSVNLTRRTLDRCQGN 262
Query: 279 IDQVLEEQTKAAQQGEPHPEFSADSPSPGL---NMELEDIAKLKMILLRLEGAIDAVELP 335
++ + + + + E GL + E A L +L E +AV P
Sbjct: 263 LETLQKTVLRIKETDEQRLRDEYRRLVEGLREASAARETDAHLANPVLPDEVLQEAV--P 320
Query: 336 GDDSGVTKPGSYIFELFAEAQITFQTKGCILDSLDQIIQHLAGRAGVFTNTAGL--QKLA 393
G ++ L + + + + +S + LA R + ++L
Sbjct: 321 GSIRTAEHFLGFLRRLLEYVKWRLRVQHVVQESPPAFLSGLAQRVCIQRKPLRFCAERLR 380
Query: 394 DIIQIVFSVDPSEGSPGSPAGLGALQSYKVHIHPDA-GHRRTAQRSDAWSTTAARKRGKV 452
++ + D ++ SP L L ++ + A G + D + T A +
Sbjct: 381 SLLHTLEITDLADFSP-----LTLLANFATLVSTYAKGFTIIIEPFDDRTPTIANP---I 432
Query: 453 LSYWCFSPGHSMHELVRQGVRSLILTSGTLAPVSSFALEMQIPFPVCLENPHIIDKHQIW 512
L + C ++ + + +S+I+TSGTL+P+ + P I+D H +
Sbjct: 433 LHFSCMDASLAIKPVFER-FQSVIITSGTLSPLDIY--------------PKILDFHPVT 477
Query: 513 VG--------------VVPRGPDGAQLSSAFDRRFSEECLSSLGKALGNIARVVPYGLLI 558
+ ++ RG D +SS F+ R + + G L ++ VVP G++
Sbjct: 478 MATFTMTLARVCLCPMIIGRGNDQVAISSKFETREDIAVIRNYGNLLLEMSAVVPDGIVA 537
Query: 559 FFPSYPVMEKSLEFWRARDLARKMEALKPLFVEPRSKGSFSETISAYYARVAAPGSTGAT 618
FF SY ME ++ W + + ++ K LF+E + S + Y + A GA
Sbjct: 538 FFTSYQYMESTVASWYEQGILENIQRNKLLFIETQDGAETSVALEKY--QEACENGRGAI 595
Query: 619 FLAVCRGKASEGLDFSDTNGRGVIVTGLPYPPRMDPRVVLKMQFLDEMKGQGGAGGQF-L 677
L+V RGK SEG+DF GR VI+ G+PY + ++++L + QF +
Sbjct: 596 LLSVARGKVSEGIDFVHHYGRAVIMFGVPYVYTQSRILKARLEYLRD---------QFQI 646
Query: 678 SGQEWYRQQASRAVNQAIGRVIRHRQDYGAVFLCDHRFAFADARAQLPSWVRPHV 732
++ A R Q +GR IR + DYG + D RFA D R +LP W++ H+
Sbjct: 647 RENDFLTFDAMRHAAQCVGRAIRGKTDYGLMVFADKRFARGDKRGKLPRWIQEHL 701
>gi|100913204 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11
isoform 2 [Homo sapiens]
Length = 856
Score = 187 bits (474), Expect = 7e-47
Identities = 178/695 (25%), Positives = 298/695 (42%), Gaps = 120/695 (17%)
Query: 106 IPKIIYASRTHSQLTQVINELRNTSYRPKVCV--LGSREQLCIHPEVKKQESNHLQIHLC 163
I KI Y SRTHSQL Q ++E++ + + V + LGSR+ LC++ +VK S L C
Sbjct: 226 ITKIYYCSRTHSQLAQFVHEVKKSPFGKDVRLVSLGSRQNLCVNEDVKSLGSVQLINDRC 285
Query: 164 ---------------------RKKVASRSCHFYNNVEEKSLEQELASPILDIEDLVKSGS 202
R++ +C FYN+ + L E + + D+E L+ G
Sbjct: 286 VDMQRSRHEKKKGAEEEKPKRRRQEKQAACPFYNHEQMGLLRDEALAEVKDMEQLLALGK 345
Query: 203 KHRVCPYYLSRNLKQQADIIFMPYNYLLDAKSRRAHNIDLKGTVVIFDEAHNVEKMCEES 262
+ R CPYY SR A ++ +PY LL A +R+A I L+ VVI DEAHN+
Sbjct: 346 EARACPYYGSRLAIPAAQLVVLPYQMLLHAATRQAAGIRLQDQVVIIDEAHNL------- 398
Query: 263 ASFDLTPHDLASGLDVIDQVLEEQTKAAQQGEPHPEFSADSPSPGLNMELEDIAKLKMIL 322
+D I + + +Q + H + G ++ +++ LK IL
Sbjct: 399 -------------IDTITGMHSVEVSGSQLCQAHSQLLQYVERYGKRLKAKNLMYLKQIL 445
Query: 323 LRLEGAIDA----VELPGDDSGVTKPGS-------YIFELFAEAQITFQTKG-CILDSLD 370
LE + ++ + +++ G+ ++F+ + F+ + C +
Sbjct: 446 YLLEKFVAVLGGNIKQNPNTQSLSQTGTELKTINDFLFQSQIDNINLFKVQRYCEKSMIS 505
Query: 371 QIIQHLAGRAGVFTNTAGLQKLADIIQIVFSVDPSE----GSPGSPAGLGALQ--SYKVH 424
+ + R G ++ KLA Q + S+ P +P + L+ S +H
Sbjct: 506 RKLFGFTERYGAVFSSREQPKLAGFQQFLQSLQPRTTEALAAPADESQASTLRPASPLMH 565
Query: 425 IHPDAGHRRTAQRSDAWSTTAARKRGKV----LSYWCFSPGHSMHELVRQGVRSLILTSG 480
I TA + ++G + L + +P ++V++ R++++ G
Sbjct: 566 IQGFLAALTTANQD---GRVILSRQGSLSQSTLKFLLLNPAVHFAQVVKE-CRAVVIAGG 621
Query: 481 TLAPVSSFALEMQIPFPVCLENPHIIDKHQIWVGVVPRGPDGAQLSSAFDRRFSEECLSS 540
T+ PVS F Q+ +E +++ FS
Sbjct: 622 TMQPVSDF--RQQLLACAGVEAERVVE-------------------------FS------ 648
Query: 541 LGKALGNIARVVPYGLLIFFPSYPVMEKSLEFWRARDLARKMEALKPLFVEPRSKGSFSE 600
G++ + P +L + + LEF +K E + +F EP+S +
Sbjct: 649 ----CGHV--IPPDNILPLVICSGISNQPLEF-----TFQKRELPQMIFQEPKSAHQVEQ 697
Query: 601 TISAYYARVAAPGS-----TGATFLAVCRGKASEGLDFSDTNGRGVIVTGLPYPPRMDPR 655
+ AY + A G TGA L+V GK SEG++FSD GR V++ G+P+P
Sbjct: 698 VLLAYSRCIQACGQERGQVTGALLLSVVGGKMSEGINFSDNLGRCVVMVGMPFPNIRSAE 757
Query: 656 VVLKMQFLDEMKGQGGAGGQFLSGQEWYRQQASRAVNQAIGRVIRHRQDYGAVFLCDHRF 715
+ KM +LD+ + A GQ G+ +AVNQ+IGR IRH++D+ +V L D R+
Sbjct: 758 LQEKMAYLDQTLPR--APGQAPPGKALVENLCMKAVNQSIGRAIRHQKDFASVVLLDQRY 815
Query: 716 AFADARAQLPSWVRPHVRVYDNFGHVIRDVAQFFR 750
A A+LP+W+R V V FG I V +F R
Sbjct: 816 ARPPVLAKLPAWIRARVEVKATFGPAIAAVQKFHR 850
Score = 57.4 bits (137), Expect = 8e-08
Identities = 35/94 (37%), Positives = 49/94 (52%), Gaps = 10/94 (10%)
Query: 13 FPFQPYKCQQEYMTKVLECLQQKVNGILESPTGTGKTLCLLCTTLAWREHLRDGISAR-- 70
FPF PY Q+++M ++ L+ GI ESPTGTGK+L L+C L+W LRD +
Sbjct: 15 FPFTPYSIQEDFMAELYRVLEAGKIGIFESPTGTGKSLSLICGALSW---LRDFEQKKRE 71
Query: 71 ---KIAERAQGELF--PDRALSSWGNAAAAAGDP 99
++ E G L D +L + AAG P
Sbjct: 72 EEARLLETGTGPLHDEKDESLCLSSSCEGAAGTP 105
>gi|132566527 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11
isoform 3 [Homo sapiens]
Length = 970
Score = 184 bits (467), Expect = 4e-46
Identities = 159/616 (25%), Positives = 269/616 (43%), Gaps = 80/616 (12%)
Query: 106 IPKIIYASRTHSQLTQVINELRNTSYRPKVCV--LGSREQLCIHPEVKKQESNHLQIHLC 163
I KI Y SRTHSQL Q ++E++ + + V + LGSR+ LC++ +VK S L C
Sbjct: 226 ITKIYYCSRTHSQLAQFVHEVKKSPFGKDVRLVSLGSRQNLCVNEDVKSLGSVQLINDRC 285
Query: 164 ---------------------RKKVASRSCHFYNNVEEKSLEQELASPILDIEDLVKSGS 202
R++ +C FYN+ + L E + + D+E L+ G
Sbjct: 286 VDMQRSRHEKKKGAEEEKPKRRRQEKQAACPFYNHEQMGLLRDEALAEVKDMEQLLALGK 345
Query: 203 KHRVCPYYLSRNLKQQADIIFMPYNYLLDAKSRRAHNIDLKGTVVIFDEAHNVEKMCEES 262
+ R CPYY SR A ++ +PY LL A +R+A I L+ VVI DEAHN+
Sbjct: 346 EARACPYYGSRLAIPAAQLVVLPYQMLLHAATRQAAGIRLQDQVVIIDEAHNL------- 398
Query: 263 ASFDLTPHDLASGLDVIDQVLEEQTKAAQQGEPHPEFSADSPSPGLNMELEDIAKLKMIL 322
+D I + + +Q + H + G ++ +++ LK IL
Sbjct: 399 -------------IDTITGMHSVEVSGSQLCQAHSQLLQYVERYGKRLKAKNLMYLKQIL 445
Query: 323 LRLEGAIDA----VELPGDDSGVTKPGS-------YIFELFAEAQITFQTKG-CILDSLD 370
LE + ++ + +++ G+ ++F+ + F+ + C +
Sbjct: 446 YLLEKFVAVLGGNIKQNPNTQSLSQTGTELKTINDFLFQSQIDNINLFKVQRYCEKSMIS 505
Query: 371 QIIQHLAGRAGVFTNTAGLQKLADIIQIVFSVDPSE----GSPGSPAGLGALQ--SYKVH 424
+ + R G ++ KLA Q + S+ P +P + L+ S +H
Sbjct: 506 RKLFGFTERYGAVFSSREQPKLAGFQQFLQSLQPRTTEALAAPADESQASTLRPASPLMH 565
Query: 425 IHPDAGHRRTAQRSDAWSTTAARKRGKV----LSYWCFSPGHSMHELVRQGVRSLILTSG 480
I TA + ++G + L + +P ++V++ R++++ G
Sbjct: 566 IQGFLAALTTANQD---GRVILSRQGSLSQSTLKFLLLNPAVHFAQVVKE-CRAVVIAGG 621
Query: 481 TLAPVSSFALEMQIPFPVCLENP------HIIDKHQIWVGVVPRGPDGAQLSSAFDRRFS 534
T+ PVS F ++ V E H+I I V+ G L F +R
Sbjct: 622 TMQPVSDFRQQLLACAGVEAERVVEFSCGHVIPPDNILPLVICSGISNQPLEFTFQKREL 681
Query: 535 EECLSSLGKALGNIARVVPYGLLIFFPSYPVMEKSLEFWRARDLARKMEALKPLFVEPRS 594
+ + +G+ L N+ VVP G++ FFPSY + + W L ++ A K +F EP+S
Sbjct: 682 PQMMDEVGRILCNLCGVVPGGVVCFFPSYEYLRQVHAHWEKGGLLGRLAARKKIFQEPKS 741
Query: 595 KGSFSETISAYYARVAAPGS-----TGATFLAVCRGKASEGLDFSDTNGRGVIVTGLPYP 649
+ + AY + A G TGA L+V GK SEG++FSD GR V++ G+P+P
Sbjct: 742 AHQVEQVLLAYSRCIQACGQERGQVTGALLLSVVGGKMSEGINFSDNLGRCVVMVGMPFP 801
Query: 650 PRMDPRVVLKMQFLDE 665
+ KM +LD+
Sbjct: 802 NIRSAELQEKMAYLDQ 817
Score = 57.4 bits (137), Expect = 8e-08
Identities = 35/94 (37%), Positives = 49/94 (52%), Gaps = 10/94 (10%)
Query: 13 FPFQPYKCQQEYMTKVLECLQQKVNGILESPTGTGKTLCLLCTTLAWREHLRDGISAR-- 70
FPF PY Q+++M ++ L+ GI ESPTGTGK+L L+C L+W LRD +
Sbjct: 15 FPFTPYSIQEDFMAELYRVLEAGKIGIFESPTGTGKSLSLICGALSW---LRDFEQKKRE 71
Query: 71 ---KIAERAQGELF--PDRALSSWGNAAAAAGDP 99
++ E G L D +L + AAG P
Sbjct: 72 EEARLLETGTGPLHDEKDESLCLSSSCEGAAGTP 105
>gi|239755744 PREDICTED: similar to Putative ATP-dependent RNA
helicase DDX11-like protein [Homo sapiens]
Length = 223
Score = 132 bits (331), Expect = 3e-30
Identities = 77/218 (35%), Positives = 116/218 (53%), Gaps = 7/218 (3%)
Query: 538 LSSLGKALGNIARVVPYGLLIFFPSYPVMEKSLEFWRARDLARKMEALKPLFVEPRSKGS 597
+ +G+ L N+ VV G++ FFPSY + + W L ++ A K +F EP+S
Sbjct: 2 MDEVGRILCNLCVVVSGGVVCFFPSYEYLRQVHAHWEKGGLLGRLAARKKIFQEPKSAHQ 61
Query: 598 FSETISAYYARVAAPGS-----TGATFLAVCRGKASEGLDFSDTNGRGVIVTGLPYPPRM 652
+ + AY + A G T A L+V GK SEG++FSD GR V++ G+P+P
Sbjct: 62 VEQVLLAYSRCIQACGQERGQVTEALLLSVVGGKMSEGINFSDNLGRCVVMVGMPFPNIR 121
Query: 653 DPRVVLKMQFLDEMKGQGGAGGQFLSGQEWYRQQASRAVNQAIGRVIRHRQDYGAVFLCD 712
+ KM +LD+ + A GQ G+ +AVNQ+IGR IRH++D+ ++ L D
Sbjct: 122 SAELQEKMAYLDQTLPR--APGQAPPGKALVENLCMKAVNQSIGRAIRHQKDFASIVLLD 179
Query: 713 HRFAFADARAQLPSWVRPHVRVYDNFGHVIRDVAQFFR 750
R+A A+LP+W+R V V FG I V +F R
Sbjct: 180 QRYARPPVLAKLPAWIRARVEVKATFGPAIAAVQKFHR 217
>gi|195947407 excision repair cross-complementing rodent repair
deficiency, complementation group 2 protein isoform 2
[Homo sapiens]
Length = 405
Score = 97.8 bits (242), Expect = 5e-20
Identities = 78/271 (28%), Positives = 116/271 (42%), Gaps = 62/271 (22%)
Query: 25 MTKVLECLQQKVNGILESPTGTGKTLCLLCTTLAWREHLRDGISARKIAERAQGELFPDR 84
M ++ L K +G+LE P+GTGKT+ LL +A++
Sbjct: 1 MRELKRTLDAKGHGVLEMPSGTGKTVSLLALIMAYQR----------------------- 37
Query: 85 ALSSWGNAAAAAGDPIACYTDIPKIIYASRTHSQLTQVINELRNT------SYRPKVCVL 138
A ++ K+IY SRT ++ +VI ELR K+ L
Sbjct: 38 ----------------AYPLEVTKLIYCSRTVPEIEKVIEELRKLLNFYEKQEGEKLPFL 81
Query: 139 G----SREQLCIHPEVKKQESNHLQIHLCRKKVASR------------SCHFYNNVEEKS 182
G SR+ LCIHPEV C AS C FY +
Sbjct: 82 GLALSSRKNLCIHPEVTPLRFGKDVDGKCHSLTASYVRAQYQHDTSLPHCRFYEEFDAHG 141
Query: 183 LEQELASPILDIEDLVKSGSKHRVCPYYLSRNLKQQADIIFMPYNYLLDAKSRRAHNIDL 242
E L + I +++DL G + CPY+L+R A+++ Y+YLLD K + +L
Sbjct: 142 REVPLPAGIYNLDDLKALGRRQGWCPYFLARYSILHANVVVYSYHYLLDPKIADLVSKEL 201
Query: 243 -KGTVVIFDEAHNVEKMCEESASFDLTPHDL 272
+ VV+FDEAHN++ +C +S S +LT L
Sbjct: 202 ARKAVVVFDEAHNIDNVCIDSMSVNLTRRTL 232
>gi|150417989 cyclin K isoform 1 [Homo sapiens]
Length = 580
Score = 41.6 bits (96), Expect = 0.005
Identities = 69/272 (25%), Positives = 98/272 (36%), Gaps = 50/272 (18%)
Query: 954 QFVRPHHKQQFEEVCIQ---LTGRGCGYRPEHSIPRRQRAQPVLDPTGRTAP----DPKL 1006
QFV+ E++C Q L +G P H+ P + + P L PT + P
Sbjct: 237 QFVQDVPVDVLEDICHQILDLYSQGKQQMPHHT-PHQLQQPPSLQPTPQVPQVQQSQPSQ 295
Query: 1007 TVSTAAAQQLDPQEHLNQGRPHLSPRPPPTGDPGSQPQWGSGVPRAGKQGQHAVSAYLAD 1066
+ + QQ DPQ+ Q +P P+ P PQ P + +Q + AV +
Sbjct: 296 SSEPSQPQQKDPQQPAQQQQPAQQPKKP-------SPQ-----PSSPRQVKRAVVVSPKE 343
Query: 1067 ARRALGSAGCSQLLAALTAYKQDDDLDKVLAVLAALTTAKP---EDFPLLHRFSMFVRPH 1123
+A A + K+ L A P PL P
Sbjct: 344 ENKA--------------AEPPPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPG 389
Query: 1124 HKQRFSQTCTDLTGRPYPGMEPPGPQEERLAVPPVLTHRAPQPGPSRSEKTGKTQSKISS 1183
TDL P P P + PP L HR P P PS S TG S SS
Sbjct: 390 -----PVDATDLPKVQIPPPAHPAPVHQ----PPPLPHRPPPPPPS-SYMTG--MSTTSS 437
Query: 1184 FLRQRPAGTVGAGGEDAGPSQSSGPP-HGPAA 1214
++ ++ + + GPS + PP +GP A
Sbjct: 438 YMSGEGYQSLQSMMKTEGPSYGALPPAYGPPA 469
>gi|112421108 capicua homolog [Homo sapiens]
Length = 1608
Score = 38.9 bits (89), Expect = 0.030
Identities = 36/151 (23%), Positives = 62/151 (41%), Gaps = 15/151 (9%)
Query: 756 MPAPAPRATAPSVRGEDAVSEAKSPGPFFSTRKAKSLDLHVPSLKQRSSGSPAAGDPESS 815
+P AP PSV+ +A A P ++ ++K +R G + DPE
Sbjct: 41 VPFLAPSQPDPSVQPSEAQQPASHP---VASNQSKEPAESAAVAHERPPGGTGSADPERP 97
Query: 816 LCVEYEQEPVPARQRPRGLLAALEH-----SEQRAGSPGE-------EQAHSCSTLSLLS 863
+ P P P G++ + + E+ +G PGE E H + LS++S
Sbjct: 98 PGATCPESPGPGPPHPLGVVESGKGPPPTTEEEASGPPGEPRLDSETESDHDDAFLSIMS 157
Query: 864 EKRPAEEPRGGRKKIRLVSHPEEPVAGAQTD 894
+ P G R+ L + P+E + ++ D
Sbjct: 158 PEIQLPLPPGKRRTQSLSALPKERDSSSEKD 188
Score = 33.5 bits (75), Expect = 1.3
Identities = 26/85 (30%), Positives = 32/85 (37%), Gaps = 8/85 (9%)
Query: 1141 PGMEPPGPQEERLAVPPVLTHRAPQPGPSRSEKTGKTQSKISSFLRQR-------PAGTV 1193
P +PPG + PP T AP P PS + T S Q P
Sbjct: 1524 PTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESGP 1583
Query: 1194 GAGGEDAGPSQSSGPPHGPAASEWG 1218
G G + P Q S PP GP+ + G
Sbjct: 1584 GQPGWEGAP-QPSPPPPGPSTAATG 1607
>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
Length = 748
Score = 37.0 bits (84), Expect = 0.11
Identities = 77/339 (22%), Positives = 124/339 (36%), Gaps = 57/339 (16%)
Query: 897 KLFMVAVKQELSQANFATFTQAL----QDYKGSDDFAALAACLGPLFAEDPKKHNLLQGF 952
+L VA++Q+ Q F QA Q + F A + + F ++ LQ
Sbjct: 154 QLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQ 213
Query: 953 YQ----FVRPHHK---------QQFEEVCIQLTGRGCGYRPEHSIPRRQRA---QPVLDP 996
Q ++ HH+ QQ + + QL + + + ++Q+A QP +
Sbjct: 214 QQQQQHLIKLHHQNQQQIQQQQQQLQRIA-QLQLQQQQQQQQQQQQQQQQALQAQPPIQQ 272
Query: 997 TGRTAPDPKLTVSTAAAQQLDPQEHLNQGRPHLSPRPPPTGDPGSQPQWGSGVPRAGKQG 1056
P P S A QQL H +P P+ PP +QP S +P Q
Sbjct: 273 PPMQQPQPP--PSQALPQQLQQMHHTQHHQPPPQPQQPPVAQ--NQP---SQLP-PQSQT 324
Query: 1057 QHAVSAYLADARRALGSAGCSQLLAALTAYKQDDDLDKVLAVLAALTTAKPEDFPLLHRF 1116
Q VS A + L + + + A +Q +V A+ TA+
Sbjct: 325 QPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQA--------- 375
Query: 1117 SMFVRPHHKQRFSQTCTDLTGRPYPGMEPPGPQEERLAVPPVLTHRAPQPGPSRSEKTGK 1176
+ V P + SQ+ + P PG + PQ ++PP PQP P + + +
Sbjct: 376 AQMVAP--GVQVSQSSLPMLSSPSPGQQVQTPQ----SMPP-----PPQPSPQPGQPSSQ 424
Query: 1177 TQSKISSFLRQRPAGTVGAGGEDAGPSQSSGPPHGPAAS 1215
S +SS P+ + PS S P P +
Sbjct: 425 PNSNVSSGPAPSPSSFL--------PSPSPQPSQSPVTA 455
>gi|213972636 tumor protein p53 binding protein 1 isoform 1 [Homo
sapiens]
Length = 1977
Score = 36.2 bits (82), Expect = 0.20
Identities = 26/110 (23%), Positives = 43/110 (39%), Gaps = 5/110 (4%)
Query: 739 GHVIRDVAQFFRVAERTMPAPAPRATAPSVRGEDAVSEAKSPGPFFSTRKAKSLDLHVPS 798
G + +++Q V E T+P + SV + + + + + +P
Sbjct: 174 GFGVLELSQSQDVEENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPI 233
Query: 799 LKQRSSGSPAAGDPESSLCVEYEQEPVPARQR-----PRGLLAALEHSEQ 843
+Q S P P + V EQ P PAR P+ +AA+E EQ
Sbjct: 234 AEQSSKDIPVTAQPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQ 283
>gi|213972634 tumor protein p53 binding protein 1 isoform 2 [Homo
sapiens]
Length = 1975
Score = 36.2 bits (82), Expect = 0.20
Identities = 26/110 (23%), Positives = 43/110 (39%), Gaps = 5/110 (4%)
Query: 739 GHVIRDVAQFFRVAERTMPAPAPRATAPSVRGEDAVSEAKSPGPFFSTRKAKSLDLHVPS 798
G + +++Q V E T+P + SV + + + + + +P
Sbjct: 174 GFGVLELSQSQDVEENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPI 233
Query: 799 LKQRSSGSPAAGDPESSLCVEYEQEPVPARQR-----PRGLLAALEHSEQ 843
+Q S P P + V EQ P PAR P+ +AA+E EQ
Sbjct: 234 AEQSSKDIPVTAQPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQ 283
>gi|5032189 tumor protein p53 binding protein 1 isoform 3 [Homo
sapiens]
Length = 1972
Score = 36.2 bits (82), Expect = 0.20
Identities = 26/110 (23%), Positives = 43/110 (39%), Gaps = 5/110 (4%)
Query: 739 GHVIRDVAQFFRVAERTMPAPAPRATAPSVRGEDAVSEAKSPGPFFSTRKAKSLDLHVPS 798
G + +++Q V E T+P + SV + + + + + +P
Sbjct: 169 GFGVLELSQSQDVEENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPI 228
Query: 799 LKQRSSGSPAAGDPESSLCVEYEQEPVPARQR-----PRGLLAALEHSEQ 843
+Q S P P + V EQ P PAR P+ +AA+E EQ
Sbjct: 229 AEQSSKDIPVTAQPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQ 278
>gi|13899309 ribosomal protein S6 kinase-like 1 [Homo sapiens]
Length = 541
Score = 36.2 bits (82), Expect = 0.20
Identities = 26/83 (31%), Positives = 37/83 (44%), Gaps = 12/83 (14%)
Query: 1141 PGMEPPG--PQEERLAVPP-------VLTHRAPQPGPSRS---EKTGKTQSKISSFLRQR 1188
P P G P ++R+A+ P +L AP P R E T +T + SS L +
Sbjct: 231 PARLPSGHAPGQDRIALEPPRTSPNLLLAGEAPSTRPQREAEGEPTARTSTSGSSDLPKA 290
Query: 1189 PAGTVGAGGEDAGPSQSSGPPHG 1211
P G + AG + +GPP G
Sbjct: 291 PGGHLHLQARRAGQNSDAGPPRG 313
>gi|37693995 Kruppel-like factor 13 [Homo sapiens]
Length = 288
Score = 36.2 bits (82), Expect = 0.20
Identities = 32/122 (26%), Positives = 44/122 (36%), Gaps = 16/122 (13%)
Query: 743 RDVAQFFRVA--------ERTMPAPAPRATAPSVRGEDAVSEAKSPGPFFSTRKAKSLDL 794
+D A F VA + PAPA R + R P P ++ A+
Sbjct: 56 KDSASLFVVARILADLNQQAPAPAPAERREGAAARKARTPCRLPPPAPEPTSPGAEGAAA 115
Query: 795 HVPSLKQRSSGSPAAGDPESSLCVEYEQEPVPARQRPRGLLAALEHSEQRAGSPGEEQAH 854
PS PA +PE +E E+EP PA GL + RA ++ H
Sbjct: 116 APPS--------PAWSEPEPEAGLEPEREPGPAGSGEPGLRQRVRRGRSRADLESPQRKH 167
Query: 855 SC 856
C
Sbjct: 168 KC 169
>gi|33286446 opioid growth factor receptor [Homo sapiens]
Length = 677
Score = 35.8 bits (81), Expect = 0.26
Identities = 30/78 (38%), Positives = 34/78 (43%), Gaps = 8/78 (10%)
Query: 1141 PGMEPPGPQEERLAVPPVLTHRAPQPGPSRSEKTGKTQSKISSFLRQRPAGTVGAGGEDA 1200
PG P GP + A P T GP+R E S RPAG AG E A
Sbjct: 562 PGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPA----ESPSETPGPRPAGP--AGDEPA 615
Query: 1201 -GPSQSSGP-PHGPAASE 1216
PS++ GP P GPA E
Sbjct: 616 ESPSETPGPRPAGPAGDE 633
Score = 32.0 bits (71), Expect = 3.7
Identities = 27/78 (34%), Positives = 36/78 (46%), Gaps = 8/78 (10%)
Query: 1141 PGMEPPGPQEERLAVPPVLTHRAPQPGPSRSEKTGKTQSKISSFLRQRPAGTVGAGGEDA 1200
PG P GP + A P T P+P ++ ++ S+ RPAG AG E A
Sbjct: 522 PGPSPAGPAGDEPAESPSET-PGPRPAGPAGDEPAESPSETPG---PRPAGP--AGDEPA 575
Query: 1201 -GPSQSSGP-PHGPAASE 1216
PS++ GP P GP E
Sbjct: 576 ESPSETPGPSPAGPTRDE 593
>gi|148762940 DVL-binding protein DAPLE [Homo sapiens]
Length = 2028
Score = 35.8 bits (81), Expect = 0.26
Identities = 52/225 (23%), Positives = 72/225 (32%), Gaps = 36/225 (16%)
Query: 994 LDPTGRTAPDPKLTVSTA----AAQQLDPQEHLNQGRPHLSPRPPPTGDPGSQPQWGSGV 1049
L P P+ +LT + A A +Q P + L+ GRP +P PP + P S+
Sbjct: 1745 LKPGQYVKPNFRLTEAEAPPSVAPRQAQPPQSLSLGRPRQAPVPPASHAPASR------- 1797
Query: 1050 PRAGKQGQHAVSAYLADARRALGSAGCSQLLAALTAYKQDDDLDKVLAVLAALTTAKPED 1109
A S AD RA G C Q + + L AL +
Sbjct: 1798 ---SASLSRAFSLASADLLRASGPEACKQ------------ESPQKLGAPEALGGRETGS 1842
Query: 1110 FPLLHRFSMFVRPHHKQRFSQTCTDLTGRPYPGMEPPGPQEERLAVPPVLTHRAPQPGPS 1169
L P ++ T L G+ + PGP+ P+ T R P
Sbjct: 1843 HTL-----QSPAPPSSHSLARERTPLVGKAGSSCQGPGPRSR-----PLDTRRFSLAPPK 1892
Query: 1170 RSEKTGKTQSKISSFLRQRPAGTVGAGGEDAGPSQSSGPPHGPAA 1214
QS + + AG AG P PAA
Sbjct: 1893 EERLAPLHQSATAPAIATAGAGAAAAGSGSNSQLLHFSPAAAPAA 1937
>gi|187960109 RNA binding motif protein 28 [Homo sapiens]
Length = 759
Score = 35.4 bits (80), Expect = 0.33
Identities = 35/131 (26%), Positives = 57/131 (43%), Gaps = 17/131 (12%)
Query: 787 RKAKSLDLHVPSLKQRSSGSPAAGDPESSLCVEYEQEPVPARQRPRGLLAALEHSEQRAG 846
RK K +L + Q+ PA G+P+ +P PA+ + + AA H+E+++
Sbjct: 583 RKLKMKELRIQRSLQKMRSKPATGEPQKG-------QPEPAKDQQQ--KAAQHHTEEQSK 633
Query: 847 SPGEEQAHSCST----LSLLSEKRPAEEPRG--GRKKIRLVSHPEEPVAGAQTDRAKLFM 900
P E++ + ST +E E P G RK + L SH + D+ K+
Sbjct: 634 VPPEQKRKAGSTSWTGFQTKAEVEQVELPDGKKRRKVLALPSHRGPKI--RLRDKGKVKP 691
Query: 901 VAVKQELSQAN 911
V K+ Q N
Sbjct: 692 VHPKKPKPQIN 702
>gi|148762978 similar to CG15216-PA [Homo sapiens]
Length = 976
Score = 35.4 bits (80), Expect = 0.33
Identities = 57/238 (23%), Positives = 85/238 (35%), Gaps = 43/238 (18%)
Query: 1002 PDPKLTVSTAAAQQLDPQEHLNQGRPHLSPRPPP--TGDPGSQPQWGSGVPRAGKQGQHA 1059
P P+ V A ++ +P+ + R +PR PP T P S P +PR G++ Q A
Sbjct: 71 PPPESAVPRARTREAEPRR---RARSKSAPRAPPGLTPAPASPPV----LPRRGREAQRA 123
Query: 1060 VSAYLADARRALGSA--GCSQLLAALTAYKQDDDLDKVLAVLAALTTAKPED---FPLLH 1114
A + R A + L + Q +V + AA P + P H
Sbjct: 124 ARAEASPRREPAYPALRALANELHPIKLQPQRGGPGRVAPLCAAAGRCAPPEPPAGPAPH 183
Query: 1115 -RFSMFVRP-----HHKQRFSQTCTDLT----GRPYP---GMEPPGPQEERLAVPPVLTH 1161
R + ++P H R S++C RP P G+ PGP+ L+ P +
Sbjct: 184 VRCRLDIKPDDAVLQHATRGSRSCGPTEAAHWARPAPQFHGLTVPGPRHMALSRTPTPSD 243
Query: 1162 R-----------APQPGP-----SRSEKTGKTQSKISSFLRQRPAGTVGAGGEDAGPS 1203
P PGP RS F + P G G+ GP+
Sbjct: 244 SYCADPRAFYCDGPLPGPRDYAERRSLPFTTPPGPTQFFYTEEPQGFRGSFAASPGPT 301
>gi|215820635 protein phosphatase 1, regulatory subunit 13 like [Homo
sapiens]
Length = 828
Score = 35.0 bits (79), Expect = 0.44
Identities = 48/201 (23%), Positives = 77/201 (38%), Gaps = 27/201 (13%)
Query: 991 QPVLDPTGRTAPDPKLTVSTAAAQQLDPQEH---LNQGRPHLSPRPPPTGDPGSQPQWG- 1046
QP P + P P+ T PQ+ +N+G P+PP +P + +
Sbjct: 415 QPQSQPQPQLPPQPQTQPQTPTPAPQHPQQTWPPVNEG----PPKPPTELEPEPEIEGLL 470
Query: 1047 SGVPRAGKQGQHAVSAYLADARRALGSAGCSQLLAALTAYKQD-DDLDKVLAVLAALTTA 1105
+ V AG + V+ L+ R L AL Q +L++V VLA +
Sbjct: 471 TPVLEAGDVDEGPVARPLSPTR----------LQPALPPEAQSVPELEEVARVLAEIPRP 520
Query: 1106 KPEDFPLLHRFSMFVRPHHKQRFSQTCTDL--------TGRPYPGMEPPGPQEERLAVPP 1157
+ ++ + P HK+++ Q + L G P P + P E A PP
Sbjct: 521 LKRRGSMEQAPAVALPPTHKKQYQQIISRLFHRHGGPGPGGPEPELSPITEGSEARAGPP 580
Query: 1158 VLTHRAPQPGPSRSEKTGKTQ 1178
AP P P+ S+ + Q
Sbjct: 581 APAPPAPIPPPAPSQSSPPEQ 601
>gi|63003907 protein phosphatase 1, regulatory subunit 13 like [Homo
sapiens]
Length = 828
Score = 35.0 bits (79), Expect = 0.44
Identities = 48/201 (23%), Positives = 77/201 (38%), Gaps = 27/201 (13%)
Query: 991 QPVLDPTGRTAPDPKLTVSTAAAQQLDPQEH---LNQGRPHLSPRPPPTGDPGSQPQWG- 1046
QP P + P P+ T PQ+ +N+G P+PP +P + +
Sbjct: 415 QPQSQPQPQLPPQPQTQPQTPTPAPQHPQQTWPPVNEG----PPKPPTELEPEPEIEGLL 470
Query: 1047 SGVPRAGKQGQHAVSAYLADARRALGSAGCSQLLAALTAYKQD-DDLDKVLAVLAALTTA 1105
+ V AG + V+ L+ R L AL Q +L++V VLA +
Sbjct: 471 TPVLEAGDVDEGPVARPLSPTR----------LQPALPPEAQSVPELEEVARVLAEIPRP 520
Query: 1106 KPEDFPLLHRFSMFVRPHHKQRFSQTCTDL--------TGRPYPGMEPPGPQEERLAVPP 1157
+ ++ + P HK+++ Q + L G P P + P E A PP
Sbjct: 521 LKRRGSMEQAPAVALPPTHKKQYQQIISRLFHRHGGPGPGGPEPELSPITEGSEARAGPP 580
Query: 1158 VLTHRAPQPGPSRSEKTGKTQ 1178
AP P P+ S+ + Q
Sbjct: 581 APAPPAPIPPPAPSQSSPPEQ 601
>gi|13470094 apolipoprotein L5 [Homo sapiens]
Length = 433
Score = 35.0 bits (79), Expect = 0.44
Identities = 23/69 (33%), Positives = 33/69 (47%), Gaps = 2/69 (2%)
Query: 1123 HHKQRFSQTCTDLTGRPYPGMEPPGPQEERLAVP-PVLTHRAPQPGPSRSEKTGKTQSKI 1181
H Q+ SQTC+ GR G P+ R +P PV+ H+ P+ GP + +T K
Sbjct: 349 HLPQKASQTCSSSRGRAVRGSRVVKPEGSRSPLPWPVVEHQ-PRLGPGVALRTPKRTVSA 407
Query: 1182 SSFLRQRPA 1190
L +PA
Sbjct: 408 PRMLGHQPA 416
>gi|61966721 Tctex1 domain containing 4 [Homo sapiens]
Length = 221
Score = 35.0 bits (79), Expect = 0.44
Identities = 23/74 (31%), Positives = 30/74 (40%)
Query: 1146 PGPQEERLAVPPVLTHRAPQPGPSRSEKTGKTQSKISSFLRQRPAGTVGAGGEDAGPSQS 1205
P P R +P + R PGP+ + + G +SF R+ GAG PS
Sbjct: 23 PSPVRPRGCLPSIDEARPAGPGPAPASRRGSMLGLAASFSRRNSLVGPGAGPGGQRPSLG 82
Query: 1206 SGPPHGPAASEWGL 1219
PP G S GL
Sbjct: 83 PVPPLGSRVSFSGL 96
>gi|209862765 RUN and SH3 domain containing 2 [Homo sapiens]
Length = 1516
Score = 34.7 bits (78), Expect = 0.57
Identities = 58/234 (24%), Positives = 79/234 (33%), Gaps = 31/234 (13%)
Query: 1006 LTVSTAAAQQLDPQEHLNQGRPHLSPRP-PPTGDPGSQPQWGSGVPRAGKQ--GQHAVSA 1062
L T + L P L G L P P PP Q S +P AG + GQ + A
Sbjct: 587 LDEGTCCSHSLPPMP-LGPGMDLLGPDPSPPWSTQVCQGPHSSEMPPAGLRATGQGPL-A 644
Query: 1063 YLADARRALGSAGCSQLLAALTAYKQDDDLDKVLAVLAALTTAKPEDFPLLHRFSMFVRP 1122
L D AL + + + D + VL +P P+ FV
Sbjct: 645 QLMDPGPALPGSPANSHTQRDARARADGGGTESRPVLRYSKEQRPTTLPI----QPFVFQ 700
Query: 1123 HH--------------KQRFSQTCTDLTGRPYPGMEP------PGPQEERLAVPPVLTHR 1162
HH Q +S + T +P P P P P E A P T R
Sbjct: 701 HHFPKQLAKARALHSLSQLYSLSGCSRTQQPAPLAAPAAQVSVPAPSGEPQASTPRATGR 760
Query: 1163 APQPGPSRSEKTGKTQSKISSFLRQRPAGTVGAGGEDAGPSQSSGPPHGPAASE 1216
+ S E + S + S+ R G G + + + S PP P A+E
Sbjct: 761 GARKAGSEPETS--RPSPLGSYSPIRSVGPFGPSTDSSASTSCSPPPEQPTATE 812
>gi|55741719 RUN and SH3 domain containing 2 [Homo sapiens]
Length = 1516
Score = 34.7 bits (78), Expect = 0.57
Identities = 58/234 (24%), Positives = 79/234 (33%), Gaps = 31/234 (13%)
Query: 1006 LTVSTAAAQQLDPQEHLNQGRPHLSPRP-PPTGDPGSQPQWGSGVPRAGKQ--GQHAVSA 1062
L T + L P L G L P P PP Q S +P AG + GQ + A
Sbjct: 587 LDEGTCCSHSLPPMP-LGPGMDLLGPDPSPPWSTQVCQGPHSSEMPPAGLRATGQGPL-A 644
Query: 1063 YLADARRALGSAGCSQLLAALTAYKQDDDLDKVLAVLAALTTAKPEDFPLLHRFSMFVRP 1122
L D AL + + + D + VL +P P+ FV
Sbjct: 645 QLMDPGPALPGSPANSHTQRDARARADGGGTESRPVLRYSKEQRPTTLPI----QPFVFQ 700
Query: 1123 HH--------------KQRFSQTCTDLTGRPYPGMEP------PGPQEERLAVPPVLTHR 1162
HH Q +S + T +P P P P P E A P T R
Sbjct: 701 HHFPKQLAKARALHSLSQLYSLSGCSRTQQPAPLAAPAAQVSVPAPSGEPQASTPRATGR 760
Query: 1163 APQPGPSRSEKTGKTQSKISSFLRQRPAGTVGAGGEDAGPSQSSGPPHGPAASE 1216
+ S E + S + S+ R G G + + + S PP P A+E
Sbjct: 761 GARKAGSEPETS--RPSPLGSYSPIRSVGPFGPSTDSSASTSCSPPPEQPTATE 812
>gi|111185957 downstream of tyrosine kinase 7 [Homo sapiens]
Length = 504
Score = 34.3 bits (77), Expect = 0.74
Identities = 27/57 (47%), Positives = 28/57 (49%), Gaps = 11/57 (19%)
Query: 807 PAAGDPESSLC------VEYEQEPVPAR---QRPRGL-LAALEHSEQRAGSPGEEQA 853
PAAG PE SLC VEY Q P R PR L LA +HS GSPG A
Sbjct: 376 PAAGAPEPSLCTCLPGTVEY-QVPTSLRAHYDTPRSLCLAPRDHSPPSQGSPGNSAA 431
>gi|109637759 calpastatin isoform f [Homo sapiens]
Length = 750
Score = 34.3 bits (77), Expect = 0.74
Identities = 37/160 (23%), Positives = 61/160 (38%), Gaps = 29/160 (18%)
Query: 753 ERTMPAPAPRATAPSVRGEDAVSEAKSPGPFFSTRKAKSLDLHVPSLKQRSSGSPAAG-- 810
++ +P PR A + R + VSE S P K S + SL S AG
Sbjct: 6 QKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRTYAGGT 65
Query: 811 -------------------DPESSLCVEYEQEPVPARQRPRGLLAALEHSEQRAGSPGEE 851
+P + V+ E E +P+ L ++A G
Sbjct: 66 ASATKVSASSGATSKSSSMNPTETKAVKTEPEKKSQSTKPKSL-------PKQASDTGSN 118
Query: 852 QAHSCSTLSLLSEKRPAEEPRGGRKKIR-LVSHPEEPVAG 890
AH+ +S +E++P+E+ + K + ++S E VAG
Sbjct: 119 DAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAG 158
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.403
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 53,879,886
Number of Sequences: 37866
Number of extensions: 2905742
Number of successful extensions: 12298
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 143
Number of HSP's that attempted gapping in prelim test: 11971
Number of HSP's gapped (non-prelim): 442
length of query: 1219
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1105
effective length of database: 13,930,794
effective search space: 15393527370
effective search space used: 15393527370
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.