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Search of human proteins with 7706537
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7706537 mitogen-activated protein kinase 8 interacting
protein 2 isoform 2 [Homo sapiens]
(797 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7706537 mitogen-activated protein kinase 8 interacting protei... 1642 0.0
gi|6912492 mitogen-activated protein kinase 8 interacting protei... 1581 0.0
gi|4885433 mitogen-activated protein kinase 8 interacting protei... 414 e-115
gi|239740950 PREDICTED: similar to mitogen-activated protein kin... 352 1e-96
gi|169211037 PREDICTED: similar to mitogen-activated protein kin... 335 1e-91
gi|58761548 tau tubulin kinase 1 [Homo sapiens] 64 4e-10
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 60 1e-08
gi|122937321 UNC homeobox [Homo sapiens] 59 2e-08
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 58 4e-08
gi|38176300 nestin [Homo sapiens] 57 9e-08
gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap... 56 2e-07
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 56 2e-07
gi|151101459 SAPS domain family, member 1 [Homo sapiens] 56 2e-07
gi|122937267 lemur tyrosine kinase 3 [Homo sapiens] 56 2e-07
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 55 2e-07
gi|7705318 GULP, engulfment adaptor PTB domain containing 1 [Hom... 55 3e-07
gi|239753314 PREDICTED: similar to RIKEN cDNA C230030N03 [Homo s... 55 3e-07
gi|116256464 hypothetical protein LOC343990 [Homo sapiens] 55 3e-07
gi|149158690 HLA-B associated transcript-2 [Homo sapiens] 54 4e-07
gi|189181750 human immunodeficiency virus type I enhancer bindin... 54 4e-07
gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap... 54 6e-07
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 54 7e-07
gi|55741677 SET domain containing 1A [Homo sapiens] 54 7e-07
gi|161169015 neuron navigator 2 isoform 3 [Homo sapiens] 54 7e-07
gi|161169013 neuron navigator 2 isoform 1 [Homo sapiens] 54 7e-07
gi|38044282 neuron navigator 2 isoform 2 [Homo sapiens] 54 7e-07
gi|116089331 human immunodeficiency virus type I enhancer bindin... 54 7e-07
gi|226437579 NAC alpha domain containing [Homo sapiens] 53 1e-06
gi|239754540 PREDICTED: NAC alpha domain containing [Homo sapiens] 53 1e-06
gi|239749105 PREDICTED: NAC alpha domain containing [Homo sapiens] 53 1e-06
>gi|7706537 mitogen-activated protein kinase 8 interacting protein 2
isoform 2 [Homo sapiens]
Length = 797
Score = 1642 bits (4252), Expect = 0.0
Identities = 797/797 (100%), Positives = 797/797 (100%)
Query: 1 MLPDFPSPSTWAPGLLLPSGPALLSPSVLQDSLSLGRSEQPHPICSFQDDFQEFEMIDDN 60
MLPDFPSPSTWAPGLLLPSGPALLSPSVLQDSLSLGRSEQPHPICSFQDDFQEFEMIDDN
Sbjct: 1 MLPDFPSPSTWAPGLLLPSGPALLSPSVLQDSLSLGRSEQPHPICSFQDDFQEFEMIDDN 60
Query: 61 EEEDDEDEEEEEEEEEGDGEGQEGGDPGSEAPAPGPLIPSPSVEEPHKHRPTTLRLTTLG 120
EEEDDEDEEEEEEEEEGDGEGQEGGDPGSEAPAPGPLIPSPSVEEPHKHRPTTLRLTTLG
Sbjct: 61 EEEDDEDEEEEEEEEEGDGEGQEGGDPGSEAPAPGPLIPSPSVEEPHKHRPTTLRLTTLG 120
Query: 121 AQDSLNNNGGFDLVRPASWQETALCSPAPEALRELPGPLPATDTGPGGAQSPVRPGCDCE 180
AQDSLNNNGGFDLVRPASWQETALCSPAPEALRELPGPLPATDTGPGGAQSPVRPGCDCE
Sbjct: 121 AQDSLNNNGGFDLVRPASWQETALCSPAPEALRELPGPLPATDTGPGGAQSPVRPGCDCE 180
Query: 181 GNRPAEPPAPGGTSPSSDPGIEADLRSRSSGGRGGRRSSQELSSPGSDSEDAGGARLGRM 240
GNRPAEPPAPGGTSPSSDPGIEADLRSRSSGGRGGRRSSQELSSPGSDSEDAGGARLGRM
Sbjct: 181 GNRPAEPPAPGGTSPSSDPGIEADLRSRSSGGRGGRRSSQELSSPGSDSEDAGGARLGRM 240
Query: 241 ISSISETELELSSDGGSSSSGRSSHLTNSIEEASSPASEPEPPREPPRRPAFLPVGPDDT 300
ISSISETELELSSDGGSSSSGRSSHLTNSIEEASSPASEPEPPREPPRRPAFLPVGPDDT
Sbjct: 241 ISSISETELELSSDGGSSSSGRSSHLTNSIEEASSPASEPEPPREPPRRPAFLPVGPDDT 300
Query: 301 NSEYESGSESEPDLSEDADSPWLLSNLVSRMISEGSSPIRCPGQCLSPAPRPPGEPVSPA 360
NSEYESGSESEPDLSEDADSPWLLSNLVSRMISEGSSPIRCPGQCLSPAPRPPGEPVSPA
Sbjct: 301 NSEYESGSESEPDLSEDADSPWLLSNLVSRMISEGSSPIRCPGQCLSPAPRPPGEPVSPA 360
Query: 361 GGAAQDSQDPEAAAGPGGVELVDMETLCAPPPPAPAAPRPGPAQPGPCLFLSNPTRDTIT 420
GGAAQDSQDPEAAAGPGGVELVDMETLCAPPPPAPAAPRPGPAQPGPCLFLSNPTRDTIT
Sbjct: 361 GGAAQDSQDPEAAAGPGGVELVDMETLCAPPPPAPAAPRPGPAQPGPCLFLSNPTRDTIT 420
Query: 421 PLWAAPGRAARPGRACSAACSEEEDEEDDEEEEDAEDSAGSPGGRGTGPSAPRDASLVYD 480
PLWAAPGRAARPGRACSAACSEEEDEEDDEEEEDAEDSAGSPGGRGTGPSAPRDASLVYD
Sbjct: 421 PLWAAPGRAARPGRACSAACSEEEDEEDDEEEEDAEDSAGSPGGRGTGPSAPRDASLVYD 480
Query: 481 AVKYTLVVDEHTQLELVSLRRCAGLGHDSEEDSGGEASEEEAGAALLGGGQVSGDTSPDS 540
AVKYTLVVDEHTQLELVSLRRCAGLGHDSEEDSGGEASEEEAGAALLGGGQVSGDTSPDS
Sbjct: 481 AVKYTLVVDEHTQLELVSLRRCAGLGHDSEEDSGGEASEEEAGAALLGGGQVSGDTSPDS 540
Query: 541 PDLTFSKKFLNVFVNSTSRSSSTESFGLFSCLVNGEEREQTHRAVFRFIPRHPDELELDV 600
PDLTFSKKFLNVFVNSTSRSSSTESFGLFSCLVNGEEREQTHRAVFRFIPRHPDELELDV
Sbjct: 541 PDLTFSKKFLNVFVNSTSRSSSTESFGLFSCLVNGEEREQTHRAVFRFIPRHPDELELDV 600
Query: 601 DDPVLVEAEEDDFWFRGFNMRTGERGVFPAFYAHAVPGPAKDLLGSKRSPCWVERFDVQF 660
DDPVLVEAEEDDFWFRGFNMRTGERGVFPAFYAHAVPGPAKDLLGSKRSPCWVERFDVQF
Sbjct: 601 DDPVLVEAEEDDFWFRGFNMRTGERGVFPAFYAHAVPGPAKDLLGSKRSPCWVERFDVQF 660
Query: 661 LGSVEVPCHQGNGILCAAMQKIATARKLTVHLRPPASCDLEISLRGVKLSLSGGGPEFQR 720
LGSVEVPCHQGNGILCAAMQKIATARKLTVHLRPPASCDLEISLRGVKLSLSGGGPEFQR
Sbjct: 661 LGSVEVPCHQGNGILCAAMQKIATARKLTVHLRPPASCDLEISLRGVKLSLSGGGPEFQR 720
Query: 721 CSHFFQMKNISFCGCHPRNSCYFGFITKHPLLSRFACHVFVSQESMRPVAQSVGRAFLEY 780
CSHFFQMKNISFCGCHPRNSCYFGFITKHPLLSRFACHVFVSQESMRPVAQSVGRAFLEY
Sbjct: 721 CSHFFQMKNISFCGCHPRNSCYFGFITKHPLLSRFACHVFVSQESMRPVAQSVGRAFLEY 780
Query: 781 YQEHLAYACPTEDIYLE 797
YQEHLAYACPTEDIYLE
Sbjct: 781 YQEHLAYACPTEDIYLE 797
>gi|6912492 mitogen-activated protein kinase 8 interacting protein 2
isoform 1 [Homo sapiens]
Length = 824
Score = 1581 bits (4094), Expect = 0.0
Identities = 767/768 (99%), Positives = 768/768 (100%)
Query: 30 QDSLSLGRSEQPHPICSFQDDFQEFEMIDDNEEEDDEDEEEEEEEEEGDGEGQEGGDPGS 89
+DSLSLGRSEQPHPICSFQDDFQEFEMIDDNEEEDDEDEEEEEEEEEGDGEGQEGGDPGS
Sbjct: 57 KDSLSLGRSEQPHPICSFQDDFQEFEMIDDNEEEDDEDEEEEEEEEEGDGEGQEGGDPGS 116
Query: 90 EAPAPGPLIPSPSVEEPHKHRPTTLRLTTLGAQDSLNNNGGFDLVRPASWQETALCSPAP 149
EAPAPGPLIPSPSVEEPHKHRPTTLRLTTLGAQDSLNNNGGFDLVRPASWQETALCSPAP
Sbjct: 117 EAPAPGPLIPSPSVEEPHKHRPTTLRLTTLGAQDSLNNNGGFDLVRPASWQETALCSPAP 176
Query: 150 EALRELPGPLPATDTGPGGAQSPVRPGCDCEGNRPAEPPAPGGTSPSSDPGIEADLRSRS 209
EALRELPGPLPATDTGPGGAQSPVRPGCDCEGNRPAEPPAPGGTSPSSDPGIEADLRSRS
Sbjct: 177 EALRELPGPLPATDTGPGGAQSPVRPGCDCEGNRPAEPPAPGGTSPSSDPGIEADLRSRS 236
Query: 210 SGGRGGRRSSQELSSPGSDSEDAGGARLGRMISSISETELELSSDGGSSSSGRSSHLTNS 269
SGGRGGRRSSQELSSPGSDSEDAGGARLGRMISSISETELELSSDGGSSSSGRSSHLTNS
Sbjct: 237 SGGRGGRRSSQELSSPGSDSEDAGGARLGRMISSISETELELSSDGGSSSSGRSSHLTNS 296
Query: 270 IEEASSPASEPEPPREPPRRPAFLPVGPDDTNSEYESGSESEPDLSEDADSPWLLSNLVS 329
IEEASSPASEPEPPREPPRRPAFLPVGPDDTNSEYESGSESEPDLSEDADSPWLLSNLVS
Sbjct: 297 IEEASSPASEPEPPREPPRRPAFLPVGPDDTNSEYESGSESEPDLSEDADSPWLLSNLVS 356
Query: 330 RMISEGSSPIRCPGQCLSPAPRPPGEPVSPAGGAAQDSQDPEAAAGPGGVELVDMETLCA 389
RMISEGSSPIRCPGQCLSPAPRPPGEPVSPAGGAAQDSQDPEAAAGPGGVELVDMETLCA
Sbjct: 357 RMISEGSSPIRCPGQCLSPAPRPPGEPVSPAGGAAQDSQDPEAAAGPGGVELVDMETLCA 416
Query: 390 PPPPAPAAPRPGPAQPGPCLFLSNPTRDTITPLWAAPGRAARPGRACSAACSEEEDEEDD 449
PPPPAPAAPRPGPAQPGPCLFLSNPTRDTITPLWAAPGRAARPGRACSAACSEEEDEEDD
Sbjct: 417 PPPPAPAAPRPGPAQPGPCLFLSNPTRDTITPLWAAPGRAARPGRACSAACSEEEDEEDD 476
Query: 450 EEEEDAEDSAGSPGGRGTGPSAPRDASLVYDAVKYTLVVDEHTQLELVSLRRCAGLGHDS 509
EEEEDAEDSAGSPGGRGTGPSAPRDASLVYDAVKYTLVVDEHTQLELVSLRRCAGLGHDS
Sbjct: 477 EEEEDAEDSAGSPGGRGTGPSAPRDASLVYDAVKYTLVVDEHTQLELVSLRRCAGLGHDS 536
Query: 510 EEDSGGEASEEEAGAALLGGGQVSGDTSPDSPDLTFSKKFLNVFVNSTSRSSSTESFGLF 569
EEDSGGEASEEEAGAALLGGGQVSGDTSPDSPDLTFSKKFLNVFVNSTSRSSSTESFGLF
Sbjct: 537 EEDSGGEASEEEAGAALLGGGQVSGDTSPDSPDLTFSKKFLNVFVNSTSRSSSTESFGLF 596
Query: 570 SCLVNGEEREQTHRAVFRFIPRHPDELELDVDDPVLVEAEEDDFWFRGFNMRTGERGVFP 629
SCLVNGEEREQTHRAVFRFIPRHPDELELDVDDPVLVEAEEDDFWFRGFNMRTGERGVFP
Sbjct: 597 SCLVNGEEREQTHRAVFRFIPRHPDELELDVDDPVLVEAEEDDFWFRGFNMRTGERGVFP 656
Query: 630 AFYAHAVPGPAKDLLGSKRSPCWVERFDVQFLGSVEVPCHQGNGILCAAMQKIATARKLT 689
AFYAHAVPGPAKDLLGSKRSPCWVERFDVQFLGSVEVPCHQGNGILCAAMQKIATARKLT
Sbjct: 657 AFYAHAVPGPAKDLLGSKRSPCWVERFDVQFLGSVEVPCHQGNGILCAAMQKIATARKLT 716
Query: 690 VHLRPPASCDLEISLRGVKLSLSGGGPEFQRCSHFFQMKNISFCGCHPRNSCYFGFITKH 749
VHLRPPASCDLEISLRGVKLSLSGGGPEFQRCSHFFQMKNISFCGCHPRNSCYFGFITKH
Sbjct: 717 VHLRPPASCDLEISLRGVKLSLSGGGPEFQRCSHFFQMKNISFCGCHPRNSCYFGFITKH 776
Query: 750 PLLSRFACHVFVSQESMRPVAQSVGRAFLEYYQEHLAYACPTEDIYLE 797
PLLSRFACHVFVSQESMRPVAQSVGRAFLEYYQEHLAYACPTEDIYLE
Sbjct: 777 PLLSRFACHVFVSQESMRPVAQSVGRAFLEYYQEHLAYACPTEDIYLE 824
>gi|4885433 mitogen-activated protein kinase 8 interacting protein 1
[Homo sapiens]
Length = 711
Score = 414 bits (1065), Expect = e-115
Identities = 261/641 (40%), Positives = 343/641 (53%), Gaps = 84/641 (13%)
Query: 190 PGGTSPSSDPGIEADLRSRSSGGRGGRRSSQELSSPGS-DSEDAGGARLGRMISSISETE 248
PG P ++ G E RG +S + PGS D+ + + ++
Sbjct: 122 PGAGPPKAESGQEP-------ASRGQGQSQGQSQGPGSGDTYRPKRPTTLNLFPQVPRSQ 174
Query: 249 LELSSDGGSSSSGRSSHLTNSIEEASSP--ASEPEPPREPPRRPAFLPVGPDDTNSEYES 306
L+++ S G+ + + +SSP E PP E LP +S
Sbjct: 175 DTLNNN----SLGKKHSWQDRVSRSSSPLKTGEQTPPHEHICLSDELPP---------QS 221
Query: 307 GSESEPDLSEDADSPWLLSNLVSRMISEGSSPIRCPGQCLSPAPRPPGEPVSPAGGAAQD 366
G D DSP C + P G P +P GG
Sbjct: 222 GPAPTTDRGTSTDSP-------------------CRRSTATQMAPPGGPPAAPPGGRGHS 262
Query: 367 SQDPEAAAGPGGVELVDMETLCAPPPPAPAAPRPGPAQPGPCLFLSNPTRDTITPLWAAP 426
+D V L E + P P P A+P +R +++ + P
Sbjct: 263 HRD--RIHYQADVRLEATEEIYLTPVQRP----PDAAEPTSAFLPPTESRMSVS---SDP 313
Query: 427 GRAARP---GRACSAACSEEEDEEDDEEEEDAEDSAGS-PGGRGTGPSAPR------DAS 476
AA P GR + EEE + E AE G G G P PR ++
Sbjct: 314 DPAAYPSTAGRPHPSISEEEEGFDCLSSPERAEPPGGGWRGSLGEPPPPPRASLSSDTSA 373
Query: 477 LVYDAVKYTLVVDEHTQLELVSLRRCAGLGHDSEEDSG-----------------GEASE 519
L YD+VKYTLVVDEH QLELVSLR C G + E DS GE E
Sbjct: 374 LSYDSVKYTLVVDEHAQLELVSLRPCFG-DYSDESDSATVYDNCASVSSPYESAIGEEYE 432
Query: 520 EEAGAALLGGGQVSGDTSPDSPDLTFSKKFLNVFVNSTSRSSSTESFGLFSCLVNGEERE 579
E +S D++PD PD+ FSKKFLNVF++ SRSSS ESFGLFSC++NGEE+E
Sbjct: 433 EAPRPQ--PPACLSEDSTPDEPDVHFSKKFLNVFMSGRSRSSSAESFGLFSCIINGEEQE 490
Query: 580 QTHRAVFRFIPRHPDELELDVDDPVLVEAEEDDFWFRGFNMRTGERGVFPAFYAHAVPGP 639
QTHRA+FRF+PRH DELEL+VDDP+LVE + +D+W+ +NMRTG RGVFPA+YA V
Sbjct: 491 QTHRAIFRFVPRHEDELELEVDDPLLVELQAEDYWYEAYNMRTGARGVFPAYYAIEVTKE 550
Query: 640 AKDLLGSKRSPCWVERFDVQFLGSVEVPCHQGNGILCAAMQKIATARKLTVHLRPPASCD 699
+ + ++ WV++F V+FLGSV+VP H+GN +LCAAMQKIAT R+LTVH PP+SC
Sbjct: 551 PEHMAALAKNSDWVDQFRVKFLGSVQVPYHKGNDVLCAAMQKIATTRRLTVHFNPPSSCV 610
Query: 700 LEISLRGVKLSLSGGGPE---FQRCSHFFQMKNISFCGCHPRNSCYFGFITKHPLLSRFA 756
LEIS+RGVK+ + + +CSHFFQ+KNISFCG HP+N+ YFGFITKHP RFA
Sbjct: 611 LEISVRGVKIGVKADDSQEAKGNKCSHFFQLKNISFCGYHPKNNKYFGFITKHPADHRFA 670
Query: 757 CHVFVSQESMRPVAQSVGRAFLEYYQEHLAYACPTEDIYLE 797
CHVFVS++S + +A+SVGRAF ++Y++ + Y CPTEDIYLE
Sbjct: 671 CHVFVSEDSTKALAESVGRAFQQFYKQFVEYTCPTEDIYLE 711
Score = 53.5 bits (127), Expect = 7e-07
Identities = 74/276 (26%), Positives = 106/276 (38%), Gaps = 51/276 (18%)
Query: 48 QDDFQEFEMIDDNEE----EDDEDEEEEEEEEEGDGEGQEGGDPGSEAPAPGPLIPSPSV 103
Q + + ++ID + EDDE++++EE G G + G E + G
Sbjct: 88 QAEMLQMDLIDATGDTPGAEDDEEDDDEERAARRPGAGPPKAESGQEPASRGQGQSQGQS 147
Query: 104 EEP------HKHRPTTLRL--TTLGAQDSLNNNGGFDLVRPASWQETALCSPAP------ 149
+ P RPTTL L +QD+LNNN L + SWQ+ S +P
Sbjct: 148 QGPGSGDTYRPKRPTTLNLFPQVPRSQDTLNNN---SLGKKHSWQDRVSRSSSPLKTGEQ 204
Query: 150 ----------EALRELPGPLPATDTGPGGAQSPVRPGCDCEGNRPAEPPA--PGGTSPSS 197
+ L GP P TD G SP R + P PPA PGG S
Sbjct: 205 TPPHEHICLSDELPPQSGPAPTTDRGT-STDSPCRRSTATQMAPPGGPPAAPPGGRGHSH 263
Query: 198 DPGI--EADLRSRSSGGRGGRRSSQELSSPGSDSEDAGGARLGRMISSISETELELSSD- 254
I +AD+R + + + +P DA A +E+ + +SSD
Sbjct: 264 RDRIHYQADVRLEA--------TEEIYLTPVQRPPDA--AEPTSAFLPPTESRMSVSSDP 313
Query: 255 ---GGSSSSGRSSHLTNSIEEASSPASEPEPPREPP 287
S++GR + EE S PE EPP
Sbjct: 314 DPAAYPSTAGRPHPSISEEEEGFDCLSSPE-RAEPP 348
>gi|239740950 PREDICTED: similar to mitogen-activated protein kinase
8 interacting protein 1 [Homo sapiens]
Length = 442
Score = 352 bits (902), Expect = 1e-96
Identities = 179/337 (53%), Positives = 233/337 (69%), Gaps = 31/337 (9%)
Query: 485 TLVVDEHTQLELVSLRRCAGLGHDSEEDSG---------------------GEASEEEAG 523
TL+VDEH QLELVSLR C G + E DS EAS +
Sbjct: 113 TLLVDEHAQLELVSLRPCFG-DYSDESDSAIVYDNCVSVSSPYESAIGEEYEEASRPQPP 171
Query: 524 AALLGGGQVSGDTSPDSPDLTFSKKFLNVFVNSTSRSSSTESFGLFSCLVNGEEREQTHR 583
A L S D++PD PD+ FSKKFLN+F++ SRSSS ESFGLFSC++N EE+EQTHR
Sbjct: 172 ACL------SKDSTPDEPDVHFSKKFLNIFMSGRSRSSSAESFGLFSCIINREEQEQTHR 225
Query: 584 AVFRFIPRHPDELELDVDDPVLVEAEEDDFWFRGFNMRTGERGVFPAFYAHAVPGPAKDL 643
+FRF+PRH DE EL+VDDP+LVE + +D+W+ +NMRTG RG F A+YA V + +
Sbjct: 226 TIFRFVPRHEDEPELEVDDPLLVELQAEDYWYEAYNMRTGARGFFTAYYAIEVTKEPEHM 285
Query: 644 LGSKRSPCWVERFDVQFLGSVEVPCHQGNGILCAAMQKIATARKLTVHLRPPASCDLEIS 703
++ WV++F V+FLGSV+VP H+G+ +L AAMQKIAT R+LTVH PP+SC LEIS
Sbjct: 286 AALAKNSDWVDQFRVKFLGSVQVPYHKGDVVLSAAMQKIATTRRLTVHFNPPSSCVLEIS 345
Query: 704 LRGVKLSLSGGGPE---FQRCSHFFQMKNISFCGCHPRNSCYFGFITKHPLLSRFACHVF 760
+RGVK+ + + +CSHFFQ+KNISF G HP+N+ YFGFITKH RFACHVF
Sbjct: 346 VRGVKIGVKADDSQEAKGNKCSHFFQLKNISFRGYHPKNNKYFGFITKHLADHRFACHVF 405
Query: 761 VSQESMRPVAQSVGRAFLEYYQEHLAYACPTEDIYLE 797
VS++S + +A+SVGRAF +++++ + Y CPTEDIYLE
Sbjct: 406 VSEDSTKALAESVGRAFQQFHKQFVEYTCPTEDIYLE 442
Score = 34.7 bits (78), Expect = 0.36
Identities = 23/74 (31%), Positives = 36/74 (48%), Gaps = 4/74 (5%)
Query: 59 DNEEEDDEDEEEEEEEEEGDGEGQEGGDPGS--EAPAPGPLIPSPSVEEPHKHRPTTLRL 116
+++EEDD++E G + + G +P S + + G S + RPTTL L
Sbjct: 17 EDDEEDDDEERAARRPGAGPPKAESGQEPASRGQGQSQGQSQGPGSGDTYRPKRPTTLNL 76
Query: 117 --TTLGAQDSLNNN 128
+QD+LNNN
Sbjct: 77 FPQVQLSQDTLNNN 90
>gi|169211037 PREDICTED: similar to mitogen-activated protein kinase
8 interacting protein 1 [Homo sapiens]
Length = 423
Score = 335 bits (859), Expect = 1e-91
Identities = 171/330 (51%), Positives = 226/330 (68%), Gaps = 31/330 (9%)
Query: 492 TQLELVSLRRCAGLGHDSEEDSG---------------------GEASEEEAGAALLGGG 530
T LELVSLR C + E DS EAS + A L
Sbjct: 101 TLLELVSLRPCFR-DYSDESDSAIVYDNCASVSSPYESAIGEEYEEASRPQPPACL---- 155
Query: 531 QVSGDTSPDSPDLTFSKKFLNVFVNSTSRSSSTESFGLFSCLVNGEEREQTHRAVFRFIP 590
S D++PD PD+ FSKKFLN+F++ SRSSS ESFGLFSC++N EE+EQTHR +FRF+P
Sbjct: 156 --SKDSTPDEPDVHFSKKFLNIFMSGRSRSSSAESFGLFSCIINREEQEQTHRTIFRFVP 213
Query: 591 RHPDELELDVDDPVLVEAEEDDFWFRGFNMRTGERGVFPAFYAHAVPGPAKDLLGSKRSP 650
RH DE EL+VDDP+LVE + +D+W+ +NMRTG RG+F A+YA V + + ++
Sbjct: 214 RHEDEPELEVDDPLLVELQAEDYWYEAYNMRTGARGIFTAYYAIEVTKEPEHMAALAKNS 273
Query: 651 CWVERFDVQFLGSVEVPCHQGNGILCAAMQKIATARKLTVHLRPPASCDLEISLRGVKLS 710
WV++F V+FLGSV+VP H+G+ +L AAMQKIAT R+LTVH PP+SC LEIS+RGVK+
Sbjct: 274 DWVDQFRVKFLGSVQVPYHKGDVVLSAAMQKIATTRRLTVHFNPPSSCVLEISVRGVKIG 333
Query: 711 LSGGGPE---FQRCSHFFQMKNISFCGCHPRNSCYFGFITKHPLLSRFACHVFVSQESMR 767
+ + +CSHFFQ+KNISF G HP+N+ YFGFITKH RFACHVFVS++S +
Sbjct: 334 IKADDSQEAKGNKCSHFFQLKNISFRGYHPKNNKYFGFITKHLADHRFACHVFVSEDSTK 393
Query: 768 PVAQSVGRAFLEYYQEHLAYACPTEDIYLE 797
+A+SVGRAF +++++ + Y CPTE+IYLE
Sbjct: 394 ALAESVGRAFQQFHKQFVEYTCPTENIYLE 423
Score = 32.7 bits (73), Expect = 1.4
Identities = 23/71 (32%), Positives = 33/71 (46%), Gaps = 4/71 (5%)
Query: 62 EEDDEDEEEEEEEEEGDGEGQEGGDPGS--EAPAPGPLIPSPSVEEPHKHRPTTLRL--T 117
EEDD++E G + + G +P S + + G S + RPTTL L
Sbjct: 17 EEDDDEERAARRPGAGPPKAESGQEPASRGQGQSQGQSQGPGSGDTYRPKRPTTLNLFPQ 76
Query: 118 TLGAQDSLNNN 128
+QD+LNNN
Sbjct: 77 VQLSQDTLNNN 87
>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
Length = 1321
Score = 64.3 bits (155), Expect = 4e-10
Identities = 128/500 (25%), Positives = 182/500 (36%), Gaps = 104/500 (20%)
Query: 43 PICSFQDDFQEFEMIDDNEEEDDEDEEEEEEEEEGDGEGQEGGDPGSEAPAPGPLIPSPS 102
P + +++ +E E ++ EEED+E+EEEEEEEEE + E +E + + A A G ++ S
Sbjct: 727 PQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVALGEVLGPRS 786
Query: 103 VEEPHKHRPTTLRL-----TTLGAQDSLNNNGGFDL----VRPASWQET-ALCSPAPEAL 152
+T R +TL A D + G + + P +T L SP
Sbjct: 787 GSSSEGSERSTDRSQEGAPSTLLADDQKESRGRASMADGDLEPEEGSKTLVLVSPGDMKK 846
Query: 153 RELPGPL-PATDTGPGGAQSP--VRP---GCDCEGNRPA----------EPPAP------ 190
+ L P D G A +P RP G + + P +PP P
Sbjct: 847 SPVTAELAPDPDLGTLAALTPQHERPQPTGSQLDVSEPGTLSSVLKSEPKPPGPGAGLGA 906
Query: 191 -------GGTSPSSDPGIEAD-----------LRSRSSGGR--------GGRRSSQELSS 224
GG + +S P + + L SSGG+ G EL+S
Sbjct: 907 GTVTTGVGGVAVTSSPFTKVERTFVHIAEKTHLNVMSSGGQALRSEEFSAGGELGLELAS 966
Query: 225 PGSDSEDAGGARL--GRMISSISETELELSSDGGSSSSGRSSHLTNSIEEASSPASEPEP 282
G E+ A L G +S ++ E+E S+ G+ S TNS+ + A P P
Sbjct: 967 DGGAVEEGARAPLENGLALSGLNGAEIEGSALSGAPRETPSEMATNSLPNGPALADGPAP 1026
Query: 283 --PREP---------PRRPAF--------LPV--GPDDTNSEYESGSESEPDLSEDADSP 321
P EP PRR A +PV +DT SE ++ S+ A
Sbjct: 1027 VSPLEPSPEKVATISPRRHAMPGSRPRSRIPVLLSEEDTGSEPSGSLSAKERWSKRARPQ 1086
Query: 322 WLLSNLVSRMISEGSSPIRCPGQCLSPA---PRPPGEPVSPAGGAAQDSQDPEAAAGPGG 378
L+ LV +G +R S + R E +S G AAA P
Sbjct: 1087 QDLARLVMEK-RQGRLLLRLASGASSSSSEEQRRASETLSGTGSEEDTPASEPAAALPRK 1145
Query: 379 VELVDMETLCAPPPPAPAAPRPGPA-QPGPCLFLSNPTRDTI--------TPLWAA---- 425
P P P P A QP + P DT TP +A
Sbjct: 1146 SGRAAATRSRIPRPIGLRMPMPVAAQQPASRSHGAAPALDTAITSRLQLQTPPGSATAAD 1205
Query: 426 ------PGRAARPGRACSAA 439
PGR PGRA + A
Sbjct: 1206 LRPKQPPGRGLGPGRAQAGA 1225
Score = 32.3 bits (72), Expect = 1.8
Identities = 31/107 (28%), Positives = 46/107 (42%), Gaps = 7/107 (6%)
Query: 442 EEEDEEDDEEEEDAEDSAGSPGGRGTGPSAPRDASLVYDAVKYTLVVDEHTQLELVSLRR 501
EEE+EE++EEEE+ E+ A + G PR S + + T E L++ +
Sbjct: 755 EEEEEEEEEEEEEEEEEAAAAVALGE-VLGPRSGSSSEGSERSTDRSQEGAPSTLLADDQ 813
Query: 502 CAGLGHDSEEDSGGEASEEEAGAALLGGGQ-----VSGDTSPDSPDL 543
G S D E E L+ G V+ + +PD PDL
Sbjct: 814 KESRGRASMADGDLEPEEGSKTLVLVSPGDMKKSPVTAELAPD-PDL 859
Score = 31.2 bits (69), Expect = 4.0
Identities = 44/167 (26%), Positives = 62/167 (37%), Gaps = 28/167 (16%)
Query: 147 PAPEALRELPGPLPATDTGPGGAQSPVRPGCDCEGNRPAEPPAPGGTSPSSDPGIEADLR 206
P P LR P+P P P D + P G++ + ADLR
Sbjct: 1157 PRPIGLRM---PMPVAAQQPASRSHGAAPALDTAITSRLQLQTPPGSATA------ADLR 1207
Query: 207 SRSSGGRG-GRRSSQELSSPGSDSEDAGGARLGRMISSISETELELSSDGGSSSSGRSSH 265
+ GRG G +Q + P + R R+ +S S +S+S RS
Sbjct: 1208 PKQPPGRGLGPGRAQAGARPPAP-------RSPRLPASTSAAR-------NASASPRSQS 1253
Query: 266 LTNSIEEASSPASEPEPPREPPRRPAFLPVGPDDTNSEYESGSESEP 312
L+ E+ SP+ + P PPR PD T S GS+ P
Sbjct: 1254 LSR--RESPSPSHQARPGVPPPRGVPPARAQPDGTPS--PGGSKKGP 1296
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 59.7 bits (143), Expect = 1e-08
Identities = 86/443 (19%), Positives = 169/443 (38%), Gaps = 70/443 (15%)
Query: 48 QDDFQEFEMIDDNEEEDDEDEEEEE--EEEEGDGEGQEGGDPGSEAPAPGPLIPSPSVEE 105
++ +E ++ ++ EE++++ +EEE EEE G+ E EGG+ +++P P+
Sbjct: 458 EEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSP------PAEEAAS 511
Query: 106 PHKHRPTTLRLTTLGAQDSLNNNGGFDLVRPASWQETALCSPAPEALRELPGPLPATDTG 165
P K + V+ + SP E + PA
Sbjct: 512 PEKEAKSP--------------------VKEEAKSPAEAKSPEKEEAKS-----PAEVKS 546
Query: 166 PGGAQSPVRPGCDCEGNRPAEPPAPGGTSPSSDPGIEADLRSRSSGGRGGRRSSQELSSP 225
P A+SP + E P E +P S +++ +++S + +E SP
Sbjct: 547 PEKAKSPAKE----EAKSPPEAKSPEKEEAKSPAEVKSPEKAKSP-------AKEEAKSP 595
Query: 226 G-SDSEDAGGARLGRMISSISETELELSSDGGSSSSGRSSHLTNS--IEEASSPASEPEP 282
+ S + + + S +E + + + S + +S S EEA SP P
Sbjct: 596 AEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSP 655
Query: 283 PREPPRRPAFLPVGPDDTNSEYESGSESEPDLSEDADSPWLLSNLV---SRMISEGSSPI 339
+E + P +E +S +++ + +A SP + V ++ + SP+
Sbjct: 656 EKEEAKSP---EKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPV 712
Query: 340 ----RCPGQCLSPAPRPPGEPVSPAGGAAQDSQDPEAAAGPGGVELVDMETLCAPPPPAP 395
+ P + SP P ++++ PE A P + +D+++ A P
Sbjct: 713 KEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKE 772
Query: 396 AAPRPGPAQPGPCLFLSNPTRDTITPLWAAPGRAARPGRACSAACSEEEDEEDD------ 449
A P P +P ++ + +P +A P + + A +E ++++
Sbjct: 773 EARSPADKFPEKA---KSPVKEEV----KSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVK 825
Query: 450 EEEEDAEDSAGSPGGRGTGPSAP 472
EEE+ E P + AP
Sbjct: 826 EEEKPQEVKVKEPPKKAEEEKAP 848
>gi|122937321 UNC homeobox [Homo sapiens]
Length = 531
Score = 58.9 bits (141), Expect = 2e-08
Identities = 90/342 (26%), Positives = 119/342 (34%), Gaps = 55/342 (16%)
Query: 107 HKHRPTTLRLTTLGAQDSLNNNGGFDLVRPASWQETALCSPAPEALRELPGPLPATDTGP 166
H H P L L + + DS + GG SP P P P P GP
Sbjct: 218 HLHSPGGLSLHSAPSSDSDSGGGGL--------------SPEP------PEPPPPAAKGP 257
Query: 167 GGAQSPVRPGCDCEGNRPAEPPAPGGTSPSSDPGIEADLRSRSSGG---RGGRRSSQELS 223
G S P EPPAPG P+ P RS G R GR + ++ +
Sbjct: 258 GAHASGAAGTAPAP---PGEPPAPGTCDPAFYPS------QRSGAGPQPRPGRPADKDAA 308
Query: 224 SPGSDSEDAGGARLGRMISSISETELE-LSSDGGSSSSGRSSHLTNSIEEASSPASEPEP 282
S G + A R + S +E L SD S+ + P
Sbjct: 309 SCGPGAAVAAVERGAAGLPKASPFSVESLLSDSPPRRKAASNAAAAAAAGLDFAPGLPCA 368
Query: 283 PREPPRRPAFL------PVGPDDTNSEYESGSESEPDLSEDADSPWL-----LSNLVSRM 331
PR + FL P+G + + G+ EP + +P +
Sbjct: 369 PRTLIGKGHFLLYPITQPLGFLVPQAALKGGAGLEPAPKDAPPAPAVPPAPPAQASFGAF 428
Query: 332 ISEGSSPIRCPGQCLSPAPRPPGEPVSPAGGAAQDSQDPEAAAGPGGVELVDMETL-CAP 390
G +P + A PG P +PA +D A G GG + D T AP
Sbjct: 429 SGPGGAPDSAFARRSPDAVASPGAP-APAPAPFRDLASAAATEGGGG-DCADAGTAGPAP 486
Query: 391 PPPAPAAPRPGPAQPGPCLFLSNPTRDTITPLWAAPGRAARP 432
PPPAP +PRPGP P +P + T PG AA P
Sbjct: 487 PPPAP-SPRPGPRPP-------SPAEEPATCGVPEPGAAAGP 520
>gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
Length = 1130
Score = 57.8 bits (138), Expect = 4e-08
Identities = 100/385 (25%), Positives = 133/385 (34%), Gaps = 87/385 (22%)
Query: 97 LIPSPSVEEPHKHRPTTLRLTTLGAQDSLNNNGGFDLVRPASWQETALCSPAPEALRELP 156
L PSP P L+ +LG ++ D + +S+ AL + A +P
Sbjct: 588 LAPSPRCPPP---LACALQAFSLGQRE--------DSLEVSSFCSEALVTCAALTHPRVP 636
Query: 157 GPLPATDTGPGGAQSPVRPGCDCEGNRPAEPPAPGGTSPSSDPGIEADLRSRSSGGRGGR 216
P T P A P P E P+P P PG + S S G
Sbjct: 637 PLQPMGPTCPTPAPVP-----------PPEAPSPFRAPPFHPPGPMPSVGSMPSAG---- 681
Query: 217 RSSQELSSPGSDSEDAGGARLGRMISSISETELELSSDGGSSSS-----GRSSHLTNSIE 271
+ S G AG R + L LS G S G +H S E
Sbjct: 682 ----PMPSAGP-MPSAGPVPSARPGPPTTANHLGLSVPGLVSVPPRLLPGPENHRAGSNE 736
Query: 272 EASSPASEPEPPREPPR--------RPAFLPVGPDDTNSEYESGSESEPDLSEDADSPWL 323
+ S PP PP RPAF+ + + E S+ E L D+D +
Sbjct: 737 DPILAPSGTPPPTIPPDETFGGRVPRPAFV-------HYDKEEASDVEISLESDSDDSVV 789
Query: 324 LSNLVSRMISEGSSPIRCP--GQCLSPAPRPPGEPV-SPAGGAAQDSQDPEAAAGPGGVE 380
+ + EG P+ P P P G P SP A ++ ++ AA GP
Sbjct: 790 I-------VPEGLPPLPPPPPSGATPPPIAPTGPPTASPPVPAKEEPEELPAAPGP---- 838
Query: 381 LVDMETLCAPPPPAPAAPRPGPAQ-PGPCLFLSNPTRDTITPLWAAPGRAARPGRACSAA 439
PPPP P P PGP P P L TP P +
Sbjct: 839 --------LPPPPPPPPPVPGPVTLPPPQLVPEG------TPGGGGPPALEEDLTVININ 884
Query: 440 CS-------EEEDEEDDEEEEDAED 457
S EEE+EE++EEEE+ ED
Sbjct: 885 SSDEEEEEEEEEEEEEEEEEEEEED 909
Score = 47.8 bits (112), Expect = 4e-05
Identities = 29/67 (43%), Positives = 41/67 (61%), Gaps = 2/67 (2%)
Query: 47 FQDDFQEFEMIDDNEEEDDEDEEEEEEEEEGDGE-GQEGGDPGSEAPAPGPLIPS-PSVE 104
F+++F+E E + EEE++++EEEEE EE D E G GG+ AP P L P+ P E
Sbjct: 931 FEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPE 990
Query: 105 EPHKHRP 111
P K +P
Sbjct: 991 SPPKVQP 997
>gi|38176300 nestin [Homo sapiens]
Length = 1621
Score = 56.6 bits (135), Expect = 9e-08
Identities = 125/569 (21%), Positives = 194/569 (34%), Gaps = 104/569 (18%)
Query: 29 LQDSLSLGRSEQPHPICSFQDDFQEFEMIDDNEEEDD---EDEE------------EEEE 73
L++ +LG+ E + S +++ QE D + +D +D+E E E+
Sbjct: 917 LEEEENLGKGEYQESLRSLEEEGQELPQSADVQRWEDTVEKDQELAQESPPGMAGVENED 976
Query: 74 EEEGDGEGQEGGDPGSEAPAPGPLIPSPSVEEPHKHRPTTLR-LTTLGAQDSLNNNGGFD 132
E E + Q+G E G L + V P + P + G + + GG +
Sbjct: 977 EAELNLREQDGFTGKEEVVEQGELNATEEVWIPGEGHPESPEPKEQRGLVEGASVKGGAE 1036
Query: 133 LVRPASWQETALCSP---APEALRELPGPLPATDTGPGGAQSPVRPGCDCEGNRPAEPPA 189
++ Q + +P AP+ L E PL D PGG Q+ G+ PA +
Sbjct: 1037 GLQDPEGQSQQVGAPGLQAPQGLPEAIEPLVEDDVAPGGDQASPEV---MLGSEPAMGES 1093
Query: 190 PGGTSPSSDPGIEADLRSRSSGGRG--GRRSSQELSSPGSDSEDAGGARLGRMISSISET 247
G P G+ GG G G + +E+ P + E R + +
Sbjct: 1094 AAGAEPGPGQGV---------GGLGDPGHLTREEVMEPPLEEESLEAKR----VQGLEGP 1140
Query: 248 ELELSSDGGSSSSGRSSHLTNSIEEASSPASEP-EPPREPPRRPAFLPVGPDDTNSEYES 306
+L GG L E + +P EPPRE G +++ +E
Sbjct: 1141 RKDLEEAGG---------LGTEFSELPGKSRDPWEPPRE----------GREESEAEAPR 1181
Query: 307 GSESE------PDLSEDADSPWLLSNLVSR----MISEGSSPIRCPGQCLSPAPRPPGEP 356
G+E DA SPW L + + + SP P +P P+P E
Sbjct: 1182 GAEEAFPAETLGHTGSDAPSPWPLGSEEAEEDVPPVLVSPSPTYTPILEDAPGPQPQAEG 1241
Query: 357 VSPAGGAAQ---------DSQDPEAAAG--PGGVELVDMETLCAPPPPAPAAPRPGPAQP 405
A Q +S+ E +G P G + E+ P
Sbjct: 1242 SQEASWGVQGRAEALGKVESEQEELGSGEIPEGPQEEGEESREESEEDELGETLPDSTPL 1301
Query: 406 GPCLFLSNPTRDTITPLWAAPGRAARPGRACSA---------------ACSEEEDEEDDE 450
G +L +PT +P W G P + + A E++E ++
Sbjct: 1302 G--FYLRSPT----SPRWDPTGEQRPPPQGETGKEGWDPAVLASEGLEAPPSEKEEGEEG 1355
Query: 451 EEEDAEDSAGSPGGRGTGPSAPRDASLVYDAVKYTLVVDEHTQLELVSLRRCAGLGHDSE 510
EEE DS S G AP + + + V + R G E
Sbjct: 1356 EEECGRDSDLSEEFEDLGTEAPFLPGVPGEVAEPLGQVPQLLLDPAAWDRDGESDGFADE 1415
Query: 511 EDSGGEASEE-----EAGAALLGGGQVSG 534
E+SG E E+ E GA G G G
Sbjct: 1416 EESGEEGEEDQEEGREPGAGRWGPGSSVG 1444
Score = 37.0 bits (84), Expect = 0.072
Identities = 80/336 (23%), Positives = 113/336 (33%), Gaps = 73/336 (21%)
Query: 6 PSPSTWAPGLLLPSGPALLSPSVLQDSLSL-GRSEQPHPICSFQDDFQEFEMIDDNEEED 64
PSP T+ P L GP + + S + GR+E + S Q++ E+ + +EE
Sbjct: 1221 PSP-TYTPILEDAPGPQPQAEGSQEASWGVQGRAEALGKVESEQEELGSGEIPEGPQEEG 1279
Query: 65 DEDEEEEEEEEEGD-----------------------GE---------GQEGGDP----- 87
+E EE EE+E G+ GE G+EG DP
Sbjct: 1280 EESREESEEDELGETLPDSTPLGFYLRSPTSPRWDPTGEQRPPPQGETGKEGWDPAVLAS 1339
Query: 88 -GSEAPAPGPLIPSPSVEEPHKHRPTTLRLTTLGAQDSLNNNGGFDLVRPASWQETALCS 146
G EAP EE + + LG + ++ P L
Sbjct: 1340 EGLEAPPSEKEEGEEGEEECGRDSDLSEEFEDLGTEAPFLPGVPGEVAEPLGQVPQLLLD 1399
Query: 147 PAP-EALRELPGPLPATDTGPGGAQSPVRPGCDCEGNRPAEPPAPGGTSPSSDPGIEADL 205
PA + E G ++G G E P G P S G L
Sbjct: 1400 PAAWDRDGESDGFADEEESGEEGE----------EDQEEGREPGAGRWGPGSSVG---SL 1446
Query: 206 RSRSSGGRGG--RRSSQELSSPGSDSEDAGGARLGRMISSISETELELSSDGGSSSSGRS 263
++ SS RG S +S P DS L ++ +T LE S + SG
Sbjct: 1447 QALSSSQRGEFLESDSVSVSVPWDDS-------LRGAVAGAPKTALETESQDSAEPSGS- 1498
Query: 264 SHLTNSIEEASSPASEPEPPREPPRRPAFLPVGPDD 299
EE S P S + P P +P G +D
Sbjct: 1499 -------EEESDPVSLEREDKVP--GPLEIPSGMED 1525
Score = 35.4 bits (80), Expect = 0.21
Identities = 45/174 (25%), Positives = 65/174 (37%), Gaps = 29/174 (16%)
Query: 59 DNEEEDDEDEEEEEEEEEGDGEGQEGGDPGSEAPAPGPLI-----------------PSP 101
D + E D +EEE EEG+ + +EG +PG+ PG + S
Sbjct: 1404 DRDGESDGFADEEESGEEGEEDQEEGREPGAGRWGPGSSVGSLQALSSSQRGEFLESDSV 1463
Query: 102 SVEEPHKHRPTTLRLTTLGAQDSLNNNGGFDLVRPASWQETALCSPAP-EALRELPGPLP 160
SV P +LR GA + D P+ +E + P E ++PGPL
Sbjct: 1464 SVSVPW---DDSLRGAVAGAPKTALETESQDSAEPSGSEEES--DPVSLEREDKVPGPLE 1518
Query: 161 ATDTGPGGAQSPVRPGCDCEGNRPAEPPAPGGTSPSSDPGIEADLRSRSSGGRG 214
P G + PG D G + P G S + G+ L G+G
Sbjct: 1519 I----PSGMED-AGPGADIIGVN-GQGPNLEGKSQHVNGGVMNGLEQSEEVGQG 1566
Score = 31.2 bits (69), Expect = 4.0
Identities = 24/83 (28%), Positives = 30/83 (36%)
Query: 169 AQSPVRPGCDCEGNRPAEPPAPGGTSPSSDPGIEADLRSRSSGGRGGRRSSQELSSPGSD 228
A R G + + PAP P+ P +E R RG R QE +
Sbjct: 143 AHEEERVGLNAQAACAPRCPAPPRGPPAPAPEVEELARRLGEAWRGAVRGYQERVAHMET 202
Query: 229 SEDAGGARLGRMISSISETELEL 251
S RLGR + E LEL
Sbjct: 203 SLGQARERLGRAVQGAREGRLEL 225
>gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sapiens]
Length = 2462
Score = 55.8 bits (133), Expect = 2e-07
Identities = 95/407 (23%), Positives = 137/407 (33%), Gaps = 63/407 (15%)
Query: 48 QDDFQEFEMIDDNEEEDDEDEEE------------EEEEEEGDGEGQEGGDP----GSEA 91
+D+ E + NEEE E+ E E GQ G P G++
Sbjct: 701 EDEEMEASGVSGNEEEMVEEAEATVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADG 760
Query: 92 PAPGPLIPSPSVEEPHKHRPTTLRLTTLGAQDSLNNNGGFDLVRPA-----SWQETALCS 146
P PGP P P + P PT T GA P +ETA
Sbjct: 761 PPPGPPTPPPE-DIPAPTEPTPASEAT-GAPTPPPAPPSPSAPPPVVPKEEKEEETAAAP 818
Query: 147 PAPEALRELPGPLPATDTGPGGAQSPVRPGCDCEGNRPAEPPAPGGTSPSSDPGIEADLR 206
P E + P G A+ PV+ C E E PA G + +++ E L+
Sbjct: 819 PVEEGEEQKPPAAEELAVDTGKAEEPVKSECTEEAE---EGPAKGKDAEAAEATAEGALK 875
Query: 207 SRSSGGRGGRRSSQELSSPGSDS-----------EDAGGARLGRMISSISETELELSSDG 255
+ G GR ++ + S DS ++A G R++S
Sbjct: 876 AEKKEGGSGRATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPR 935
Query: 256 GSSSSGRSSHLTNSIEEASS-----PASEPEPPRE--PPRRPAFLPVGPDDTNSEYESGS 308
++S + L + A++ EPPRE P +PA P P N + ES +
Sbjct: 936 ANASPQKPLDLKQLKQRAAAIPPIQVTKVHEPPREDAAPTKPA-PPAPPPPQNLQPESDA 994
Query: 309 ESEPDLS-------------EDADSPWLLSNLVSRMIS-EGSSPIRCPGQCLSPAPRPPG 354
+P S ++A+ P + G P G P P PP
Sbjct: 995 PQQPGSSPRGKSRSPAPPADKEAEKPVFFPAFAAEAQKLPGDPPCWTSG---LPFPVPPR 1051
Query: 355 EPVSPAGGAAQDSQDPEAAAG-PGGVELVDMETLCAPPPPAPAAPRP 400
E + + A S A G P + L D P PP + P P
Sbjct: 1052 EVIKASPHAPDPSAFSYAPPGHPLPLGLHDTARPVLPRPPTISNPPP 1098
Score = 40.0 bits (92), Expect = 0.009
Identities = 59/272 (21%), Positives = 93/272 (34%), Gaps = 38/272 (13%)
Query: 265 HLTNSIEEASSPASEPEPPREPPRRPAFLPVGPDD-------TNSEYESGSESEPDLSED 317
H +E ++ + + P AF PV D+ + +E E E+E ++
Sbjct: 669 HKLKMEKERNARRKKKKAPAAASEEAAFPPVVEDEEMEASGVSGNEEEMVEEAEATVNNS 728
Query: 318 ADSPWLLSNLVSRMISEGSSPIRCPGQCLSPAPRPPGEPVSPAGGAAQDSQDPEAAAGPG 377
+D+ + S G + + P + P PPG P P PE P
Sbjct: 729 SDTESIPSPHTEAAKDTGQNGPKPPATLGADGP-PPGPPTPP----------PEDIPAPT 777
Query: 378 GVELVDMETLCAPPPPAPAAPRPGPAQPGPCLFLSNPTRDTITPLWAAPGRAARPGRACS 437
T PPPAP P P+ P P + +T G +P A
Sbjct: 778 EPTPASEATGAPTPPPAP----PSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPAAEE 833
Query: 438 AACSEEEDEEDDEEE--EDAEDSAGSPGGRGTGPSAPRDASLVYDAVKYTLVVD-EHTQL 494
A + EE + E E+AE+ GP+ +DA + L + +
Sbjct: 834 LAVDTGKAEEPVKSECTEEAEE----------GPAKGKDAEAAEATAEGALKAEKKEGGS 883
Query: 495 ELVSLRRCAGLGHDSEED---SGGEASEEEAG 523
+ + +G DS+ S E E E G
Sbjct: 884 GRATTAKSSGAPQDSDSSATCSADEVDEAEGG 915
Score = 31.2 bits (69), Expect = 4.0
Identities = 65/274 (23%), Positives = 89/274 (32%), Gaps = 62/274 (22%)
Query: 59 DNEEEDDEDEEEEEE------------------EEEGDGEGQEGGDPGSEA-PAP----- 94
D + E D D E E+ E+ G GG GS + PA
Sbjct: 1790 DRDRERDRDREREKSILTSTTTVEHAPIWRPGTEQSSGSSGSSGGGGGSSSRPASHSHAH 1849
Query: 95 --GPLIPSPSVEEPHKHRPTTLRLTTL---------GAQDSLNNNGGFDLVRPASWQETA 143
P+ SP ++ + RP+ L T + L + VRPA+ A
Sbjct: 1850 QHSPI--SPRTQDALQQRPSVLHNTGMKGIITAVEPSTPTVLRSTSTSSPVRPAATFPPA 1907
Query: 144 LCSPAPEALR----ELPGPLPATDTGPGGAQSPVRPGCDCEGNRPAEPPAPGGTSPSSDP 199
P L L P+ P A+ P RP D A+PPA G P+S P
Sbjct: 1908 THCPLGGTLDGVYPTLMEPVLLPKEAPRVAR-PERPRADTGHAFLAKPPARSGLEPASSP 1966
Query: 200 --GIE-----------ADLRSRSSGGRGGRRSSQELSSPGSDSEDAGGARLGRMISSISE 246
G E A + + +S + +P + + D + SI E
Sbjct: 1967 SKGSEPRPLVPPVSGHATIARTPAKNLAPHHASPDPPAPPASASDPHREKTQSKPFSIQE 2026
Query: 247 TELELSSDGGSSSSGRSSHLTNSIEEASSPASEP 280
EL GSS S E SP S P
Sbjct: 2027 LELRSLGYHGSSYSPEG-------VEPVSPVSSP 2053
Score = 30.4 bits (67), Expect = 6.8
Identities = 33/135 (24%), Positives = 45/135 (33%), Gaps = 35/135 (25%)
Query: 373 AAGPGGV-ELVDMETLCAPPPPAPAAPRPG-------PAQPGPCLFLSNPTRDTITPLWA 424
AAGP G+ +L + L PP P P P P P F S + ++P
Sbjct: 1716 AAGPRGIIDLSQVPHLPVLVPPTPGTPATAMDRLAYLPTAPQP--FSSRHSSSPLSP--G 1771
Query: 425 APGRAARPGRACSAACSEEEDEEDDEEEE-----------------------DAEDSAGS 461
P +P S+ + D E D + E + S+GS
Sbjct: 1772 GPTHLTKPTTTSSSERERDRDRERDRDREREKSILTSTTTVEHAPIWRPGTEQSSGSSGS 1831
Query: 462 PGGRGTGPSAPRDAS 476
GG G S P S
Sbjct: 1832 SGGGGGSSSRPASHS 1846
>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
Length = 2968
Score = 55.8 bits (133), Expect = 2e-07
Identities = 74/287 (25%), Positives = 97/287 (33%), Gaps = 62/287 (21%)
Query: 139 WQETALCSPAPEALRELPGPLPATDTGPGGAQSPVRPGCDCEGNRPAEPPAPGGT----- 193
WQE P++L L PA G+ P P A+ P PG T
Sbjct: 2492 WQE-------PKSLLSLGSYPPAA-----GSSEPKAPWPKATDGDLAQEPGPGLTFEDSG 2539
Query: 194 SPSSDPGIEADL------RSRSSGGRGGRRSSQELSSPGSDSE---------DAGGARLG 238
+P S +A+ S SS G SS SS GS++E D G G
Sbjct: 2540 NPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGG 2599
Query: 239 RMISSISETELELSSDGGSSSSGRSSHLTNSIEEASSPASEPEPPREPPRRPAFLPVGPD 298
R S+ S +S SSSS SS ++S +SS +S
Sbjct: 2600 RNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSS------------------- 2640
Query: 299 DTNSEYESGSESEPDLSEDADSPWLLSNLVSRMISEGSSPIRCPGQCLSPAPRPPGEPVS 358
++S S S S S + S S+ S E SS +P P +
Sbjct: 2641 -SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAAL 2699
Query: 359 PAGGAAQDSQDPEAAAGPGGVELVDMETLCAPPPPAPAAPRPGPAQP 405
P Q + +A PG P P P AP P P QP
Sbjct: 2700 PTKATKQAGKARPSAHSPGK----------KTPAPQPQAPPPQPTQP 2736
Score = 53.1 bits (126), Expect = 1e-06
Identities = 96/396 (24%), Positives = 136/396 (34%), Gaps = 84/396 (21%)
Query: 79 GEGQEGGDPGSEAP--------------APGPLIPSPSVEEPHKHRPTT-LRL---TTLG 120
GEG++GG GSE P A G + P P+T L L +T G
Sbjct: 2312 GEGKDGGTAGSEEPGAKARGRGRKPSAKAKGDRAATLEEGNPTDEVPSTPLALEPSSTPG 2371
Query: 121 AQDS----LNNNGGFDLVRPASWQETA-----LCSPAPEALRELPGP-----------LP 160
++ S ++ RPA Q + PAPE ELP P +P
Sbjct: 2372 SKKSPPEPVDKRAKAPKARPAPPQPSPAPPAFTSCPAPEPFAELPAPATSLAPAPLITMP 2431
Query: 161 ATDTGP--------GGAQSPVRPGCDCEGNRPAEPPAPGGTSPSSDPGIEADLRSRSSGG 212
AT P GA+ P RPG + E + G TSP S EA L R G
Sbjct: 2432 ATRPKPKKARAAEESGAKGPRRPGEEAE--LLVKLDHEGVTSPKSKKAKEA-LLLREDPG 2488
Query: 213 RGGRRSSQELSSPGSDSEDAGGARLGRMISSISETEL----------------------E 250
GG + + L S GS AG + ++ +L +
Sbjct: 2489 AGGWQEPKSLLSLGSYPPAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQ 2548
Query: 251 LSSDG---GSSSSGRSSHLTNSIEEASSPASEPEPPREPPRRPAFLPVGPDDTNSEYESG 307
DG SSS SS ++S +SS SE E E G + + +G
Sbjct: 2549 AEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEE----------GDKNGDGGCGTG 2598
Query: 308 SESEPDLSEDADSPWLLSNLVSRMISEGSSPIRCPGQCLSPAPRPPGEPVSPAGGAAQDS 367
+ S A SP S+ S S SS S + S + ++ S
Sbjct: 2599 GRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2658
Query: 368 QDPEAAAGPGGVELVDMETLCAPPPPAPAAPRPGPA 403
+++ D ++ C+ A AP GP+
Sbjct: 2659 SSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPS 2694
Score = 50.4 bits (119), Expect = 6e-06
Identities = 85/338 (25%), Positives = 120/338 (35%), Gaps = 71/338 (21%)
Query: 6 PSPSTWAPGLLLP----SGPALLSPSVLQDSLSLGRSEQP-------HPIC--------- 45
PS S P LL + A P + + L+ R+ +P P C
Sbjct: 1751 PSSSKLTPSLLCSMVAKNSKAAGGPKLTKRGLAAPRTLKPKPATSRKQPFCLLLREAEAR 1810
Query: 46 -SFQDDFQEFEMIDDNEEEDDEDEEEEEEEEEGDGEGQEGG-----DPGSEAPAPGPL-- 97
SF D +E D++ EE+DE+EE EEE+E G + G PG E G L
Sbjct: 1811 SSFSDSSEESFDQDESSEEEDEEEELEEEDEASGGGYRLGARERALSPGLEESGLGLLAR 1870
Query: 98 -----IPSPSV---------EEPHKHRPTTLRLTTLGAQDSLNNNGGFDLVRPAS----- 138
+PSP+V E K R R + LG + ++ VR S
Sbjct: 1871 FAASALPSPTVGPSLSVVQLEAKQKARKKEERQSLLGTEFEYTDSESEVKVRKRSPAGLL 1930
Query: 139 WQETALCSPAPEALRELPGPLPATDTGPGGAQSPVRPGCDCEGNR-PAEPPAPGGTSPSS 197
+ L P P PG + P A+ V G R P EP G S
Sbjct: 1931 RPKKGLGEPGPSLAAPTPGARGPDPSSPDKAKLAVEKGRKARKLRGPKEPGFEAGPEASD 1990
Query: 198 DPGIEADLRSRSSGGRGGRRSSQELSSPGSDSEDAGGARLGRMISSISETELELSSDGGS 257
D DL +R RRS + S + A +S+ T+ + GG
Sbjct: 1991 D-----DLWTR-------RRSERIFLHDASAAAPA-------PVSTAPATKTSRCAKGGP 2031
Query: 258 SS----SGRSSHLTNSIEEASSPASEPEPPREPPRRPA 291
S +GR+ + ++ + P PPR PA
Sbjct: 2032 LSPRKDAGRAKDRKDPRKKKKGKEAGPGAGLPPPRAPA 2069
Score = 45.1 bits (105), Expect = 3e-04
Identities = 93/414 (22%), Positives = 150/414 (36%), Gaps = 74/414 (17%)
Query: 191 GGTSPSSDPGIEADLRSR--SSGGRGGRRSSQELSSPGSDSEDAGGARLGRMISSISETE 248
GGT+ S +PG +A R R S+ +G R ++ E +P + + T
Sbjct: 2317 GGTAGSEEPGAKARGRGRKPSAKAKGDRAATLEEGNPTDE---------------VPSTP 2361
Query: 249 LELSSDGGSSSSGRSSHLTNSIEE-ASSPASEPEPPREPPRRPAFLPVGPDDTNSEYESG 307
L L SS+ G +++ A +P + P PP+ P PAF + +E +
Sbjct: 2362 LALEP---SSTPGSKKSPPEPVDKRAKAPKARPAPPQPSPAPPAFTSCPAPEPFAELPAP 2418
Query: 308 SES---EPDLSEDADSPWLLSNLVSRMISE-GSSPIRCPGQCLSPAPRPPGEPV-SPAGG 362
+ S P ++ A P +R E G+ R PG+ + E V SP
Sbjct: 2419 ATSLAPAPLITMPATRP---KPKKARAAEESGAKGPRRPGEEAELLVKLDHEGVTSPKSK 2475
Query: 363 AAQDS----QDPEAAAGPGGVELVDMETLCAPPPPA----PAAPRPGPA------QPGPC 408
A+++ +DP A G E + +L + PP A P AP P +PGP
Sbjct: 2476 KAKEALLLREDPGAG---GWQEPKSLLSLGSYPPAAGSSEPKAPWPKATDGDLAQEPGPG 2532
Query: 409 LFL------SNPTRDTITPLWAAPGRAARPGRACSAACSEEEDEEDDEEEEDAEDSAGSP 462
L +P + A ++ + S++ S E E + E
Sbjct: 2533 LTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGD 2592
Query: 463 GGRGTGPSAPRDASLVYDAVKYTLVVDEHTQLELVSLRRCAGLGHDSEEDSGGEASEEEA 522
GG GTG R+ S S R + S S +S +
Sbjct: 2593 GGCGTG---GRNCS-------------------AASSRAASPASSSSSSSSSSSSSSSSS 2630
Query: 523 GAALLGGGQVSGDTSPDSPDLTFSKKFLNVFVNSTSRSSSTESFGLFSCLVNGE 576
++ S +S S + S + +S+S SSS+ + SC + E
Sbjct: 2631 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDE 2684
Score = 40.4 bits (93), Expect = 0.007
Identities = 50/207 (24%), Positives = 69/207 (33%), Gaps = 29/207 (14%)
Query: 88 GSEAPAPGPLIPSPSVEEPHKHRPTTLRLTTLGAQDSLNNNGGFDLVRPASWQETALCSP 147
G A PGP + P P + GA++S +++ +S ++ S
Sbjct: 2523 GDLAQEPGPGLTFEDSGNPKS--PDKAQAEQDGAEESESSSS-------SSSGSSSSSSS 2573
Query: 148 APEALRELPGPLPATDTGPGGAQSPVRPGCDCEGNRPAEPPAPGGTSPSSDPGIEADLRS 207
+ + E G G GG + R C +R A P + +S SS + S
Sbjct: 2574 SSSSGSETEGEEEGDKNGDGGCGTGGR-NCSAASSRAASPASSSSSSSSSSSSSSSSSSS 2632
Query: 208 RSSGGRGGRRSSQELSSPGSDSEDAGGARLGRMISSISETELELSSDGGSSSSGRSSHLT 267
SS SS SS S S + SS SSSS SS T
Sbjct: 2633 SSSSSSSSSSSSSSSSSSSSSSSSS-------------------SSSSSSSSSSSSSSTT 2673
Query: 268 NSIEEASSPASEPEPPREPPRRPAFLP 294
+ SS P P A LP
Sbjct: 2674 DEDSSCSSDDEAAPAPTAGPSAQAALP 2700
Score = 33.9 bits (76), Expect = 0.61
Identities = 34/123 (27%), Positives = 50/123 (40%), Gaps = 21/123 (17%)
Query: 348 PAPRPPGEPVSPAGGAAQDSQDPEAAAGPGGVELVDMETLCAPPP--PAPAAPRPGPAQP 405
PA P ++P+ + +++ +AA GP + L AP P PA R P
Sbjct: 1747 PAQGPSSSKLTPSLLCSMVAKNSKAAGGPK----LTKRGLAAPRTLKPKPATSRKQPF-- 1800
Query: 406 GPCLFLSNPTRDTITPLWAAPGRAARPGRACSAACSEEEDEEDDEEEEDAEDSAGSPGGR 465
CL L A R++ + + +E EE+DEEEE E+ S GG
Sbjct: 1801 --CLLLRE-----------AEARSSFSDSSEESFDQDESSEEEDEEEELEEEDEASGGGY 1847
Query: 466 GTG 468
G
Sbjct: 1848 RLG 1850
Score = 30.0 bits (66), Expect = 8.8
Identities = 65/284 (22%), Positives = 93/284 (32%), Gaps = 49/284 (17%)
Query: 165 GPGGAQSPVRPGCDCEGNRPAEPPA---PGGTSPSSDPGIEADLRSRSSGGRGGRRSSQE 221
GPGG P G+ + P+ PGG S P + R + R GR
Sbjct: 159 GPGG-DGFYLPTAGAPGSLHSHAPSARTPGGGHSSGAPAKGSSSRDGPAKERAGRGGEPP 217
Query: 222 ----LSSPGSDSEDAGGARLGRMISSISETELELSSDGGSSSSGRSSHLTNSIEEASSPA 277
P + E+A G R ++ E E D G + L+ + E+ +
Sbjct: 218 PLFGKKDPRARGEEASGPR--GVVDLTQEARAEGRQDRGPPRL--AERLSPFLAESKTKN 273
Query: 278 SEPEPPREPPRRPAFLPVGPDDTNSEYESGSESEPDLSEDADSPWLLSNLVSRMISEGSS 337
+ +P VG +E G E ++ +R++ +
Sbjct: 274 AALQPSVLTMCNGGAGDVGLPALVAEAGRGGAKEAARQDEG----------ARLLRRTET 323
Query: 338 PIRCPGQCLSPAPRPPGEPVSPAGGAAQDSQDPEAAAGPGGVELVDME-----TLCAP-- 390
+ P C SP P PP P P AA P GV V E + AP
Sbjct: 324 LLPGPRPCPSPLPPPPAPPKGPPA---------PPAATPAGVYTVFREQGREHRVVAPTF 374
Query: 391 -PPPAPAAPRPGPAQPGPCLFLSNPTRDTITPLWAAPGRAARPG 433
P RPGP Q +++ RD A A RPG
Sbjct: 375 VPSVEAFDERPGPIQ------IASQARDA----RAREREAGRPG 408
>gi|151101459 SAPS domain family, member 1 [Homo sapiens]
Length = 881
Score = 55.8 bits (133), Expect = 2e-07
Identities = 57/180 (31%), Positives = 73/180 (40%), Gaps = 17/180 (9%)
Query: 59 DNEEEDDEDEEEEEEEEEGDGEGQEGGDPGSEAPAPGPLIPSPSVEEPHKHRPTTLRLTT 118
D+E+E++EDEEEE E+EEG G GG P+PGP P PS PT
Sbjct: 669 DSEDEEEEDEEEE-EDEEGIGCAARGGATPLSYPSPGPQPPGPSWTATFDPVPT------ 721
Query: 119 LGAQDSLNNNGGFDLVRPASWQETALCSPAPEALRELPGPLPATDTGPGGAQSPVRPGCD 178
A S +G +L + L P + L P PA D +Q P P
Sbjct: 722 -DAPTSPRVSGEEELHTGPPAPQGPLSVPQGLPTQSLASP-PARDALQLRSQDPTPPSAP 779
Query: 179 ---CEGNRPAEPPAPGGTSPSSDPGIEADLRSRSSGGRGGRRSSQELSSPGSDSEDAGGA 235
EG++ EP AP S DL++ G R SS + S S A GA
Sbjct: 780 QEATEGSKVTEPSAPCQALVSI-----GDLQATFHGIRSAPSSSDSATRDPSTSVPASGA 834
Score = 46.2 bits (108), Expect = 1e-04
Identities = 74/326 (22%), Positives = 115/326 (35%), Gaps = 56/326 (17%)
Query: 44 ICSFQDDFQEFEMIDDNEEEDDEDEEEEEEEEEGDGEGQEGGDPGSEAPAPGPLIPSPSV 103
IC ++D Q+F+ +D+E+E+EEE + G+ +G++G GS+ L P V
Sbjct: 611 IC-YKDRIQQFD-------DDEEEEDEEEAQGSGESDGEDGAWQGSQLARGARLGQPPGV 662
Query: 104 EEPHKHRPTTLRLTTLGAQDSLNNNGGFDLVRPASWQETALCSPAPEALRELPGPLPATD 163
T ++ + G + SP P+ PGP
Sbjct: 663 RSGGS---TDSEDEEEEDEEEEEDEEGIGCAARGGATPLSYPSPGPQP----PGPSWTAT 715
Query: 164 TGPGGAQSPVRPGCDCEGNRPAEPPAPGGTSPSSDP-GIEADLRSRSSGGRGGRRSSQEL 222
P +P P E PPAP G P S P G+ + + SQ+
Sbjct: 716 FDPVPTDAPTSPRVSGEEELHTGPPAPQG--PLSVPQGLPTQSLASPPARDALQLRSQDP 773
Query: 223 SSPGSDSEDAGGARLGRMISSISETELELSSDGGSSSSGRSSHLTNSIEEASSPASEPEP 282
+ P + E G++ ++ S L S G ++ S+P+S
Sbjct: 774 TPPSAPQEATEGSK----VTEPSAPCQALVSIGDLQATFHGIR--------SAPSSSDSA 821
Query: 283 PREPPRRPAFLPVGPDDTNSEYESGSESEPDLSEDADSPWLLSNLVSRMISEGSSPIRCP 342
R+P + S SG+ P +E SP L P
Sbjct: 822 TRDP-------------STSVPASGAHQPPQTTEGEKSPEPL-----------GLPQSQS 857
Query: 343 GQCLSPAPRPPGEPVSPAGGAAQDSQ 368
Q L+P P P G +P G A+ SQ
Sbjct: 858 AQALTPPPIPNGS--APEGPASPGSQ 881
Score = 33.9 bits (76), Expect = 0.61
Identities = 56/235 (23%), Positives = 84/235 (35%), Gaps = 17/235 (7%)
Query: 181 GNRPAEPPA--PGGTSPSSDPGIEADLRSRSSGGRG--GRRSSQELSSPGSDSEDAGGAR 236
G R +PP GG++ S D E + G G R + LS P + G +
Sbjct: 653 GARLGQPPGVRSGGSTDSEDEEEEDEEEEEDEEGIGCAARGGATPLSYPSPGPQPPGPSW 712
Query: 237 LGRM--ISSISETELELSSDGGSSSSGRSSHLTNSIEEASSPASEPEPP-REPPRRPAFL 293
+ + + T +S + + + S+ + S PP R+ + +
Sbjct: 713 TATFDPVPTDAPTSPRVSGEEELHTGPPAPQGPLSVPQGLPTQSLASPPARDALQLRSQD 772
Query: 294 PVGPDDTNSEYESGSESEPDLSEDADSPWLLSNLVSRMISEGSSPIRCPGQCLSPAPRPP 353
P P E +EP S + + +L + S+P A R P
Sbjct: 773 PTPPSAPQEATEGSKVTEP--SAPCQALVSIGDLQATFHGIRSAP-----SSSDSATRDP 825
Query: 354 GEPVSPAGGAAQDSQDPEAAAGPGGVELVDMETLCA-PPPPAPAAPRP-GPAQPG 406
V PA GA Q Q E P + L ++ A PPP P P GPA PG
Sbjct: 826 STSV-PASGAHQPPQTTEGEKSPEPLGLPQSQSAQALTPPPIPNGSAPEGPASPG 879
Score = 33.1 bits (74), Expect = 1.0
Identities = 22/52 (42%), Positives = 28/52 (53%), Gaps = 13/52 (25%)
Query: 432 PG-RACSAACSEEEDEEDDEEEEDAED------------SAGSPGGRGTGPS 470
PG R+ + SE+E+EED+EEEED E S SPG + GPS
Sbjct: 660 PGVRSGGSTDSEDEEEEDEEEEEDEEGIGCAARGGATPLSYPSPGPQPPGPS 711
>gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]
Length = 1489
Score = 55.8 bits (133), Expect = 2e-07
Identities = 70/245 (28%), Positives = 89/245 (36%), Gaps = 48/245 (19%)
Query: 65 DEDEEEEEEEEEGDGEGQEGGDPGSEAPAPGPLIPSPSVEEPHKHRPTTLRLTTLGAQDS 124
+E+EEEEE G+ GG P P P PL R L D+
Sbjct: 668 EEEEEEEEGSSPGEDSSSLGGGPSRRGPLPCPLC----------SREGACSCLPLERGDA 717
Query: 125 LNNNGGFD-LVRPASWQETALCSPAPEALRELPGPLPATDTGP-----GGAQSPVRPGCD 178
+ GG L P ++ + +L +LP PA+ GA +P PG
Sbjct: 718 VAGWGGHPALGCPHPPEDDSSLRAERGSLADLPMAPPASAPPEFLDPLMGAAAPQYPG-- 775
Query: 179 CEGNRPAEPPAPGGTSPSSDPGIEADLRSR-SSGGRGGRRSSQELSSPGSDSEDAGGARL 237
G PA PP P +DP D S +S G G LSSPG D+G
Sbjct: 776 -RGPPPAPPPPPPPPRAPADPAASPDPPSAVASPGSG-------LSSPGPKPGDSG---- 823
Query: 238 GRMISSISETELELSSDGGSSSSGRSSHLTNSIEEASSPASEPEPP----REPPRRPAFL 293
ETE S +G G + E P + PEPP PP P L
Sbjct: 824 -------YETETPFSPEGAFPGGGAAEE-----EGVPRPRAPPEPPDPGAPRPPPDPGPL 871
Query: 294 PV-GP 297
P+ GP
Sbjct: 872 PLPGP 876
Score = 50.4 bits (119), Expect = 6e-06
Identities = 143/628 (22%), Positives = 200/628 (31%), Gaps = 150/628 (23%)
Query: 4 DFPSPSTWAPGLLLPSGPALLSPSVLQDSLSLGRSEQPHPICSFQDDFQEFEMIDDNEEE 63
D P P W P P L SP L D P + + + + +
Sbjct: 457 DGPFPWPWPPAHSAPRPGTLSSPFPLLDGFP---GADPDDVLTVTESSRGLNL------- 506
Query: 64 DDEDEEEEEEEEEGDGEGQEGGDPGSEAPAPGP--------------LIPSPSVEEPHKH 109
E E+ G G G P S PAP ++P S P
Sbjct: 507 --ECLWEKARRGAGRGGGAPAWQPASAPPAPHANPSNPFYEALSTPSVLPVISARSPSVS 564
Query: 110 RPTTLRLTTLGAQDSLNNNGGFDLVRPASWQETALCSPA--PEALREL--------PGPL 159
+RL G+ +D + P A +P+ P+ + E P P
Sbjct: 565 SEYYIRLEEHGSPPEPLFPNDWDPLDPGVPAPQAPQAPSEVPQLVSETWASPLFPAPRPF 624
Query: 160 PATDTGPGGAQSPVRPGCDCEGNRPAEP----PAPGGTSPSSDPGIEADLRSRSSGGRGG 215
PA + G S + G D EG E PA + P +E +
Sbjct: 625 PAQSSASG---SFLLSGWDPEGRGAGETLAGDPAEVLGERGTAPWVEEE----------- 670
Query: 216 RRSSQELSSPGSDSEDAGG--ARLGRMISSISETELELSS---DGGSSSSGRSSHLTNSI 270
+E SSPG DS GG +R G + + E S + G + +G H
Sbjct: 671 -EEEEEGSSPGEDSSSLGGGPSRRGPLPCPLCSREGACSCLPLERGDAVAGWGGH----- 724
Query: 271 EEASSPASE-PEPPREPPRRPAFLPVGPDDTNSEYESGSESEPDLSEDADSP-WLLSNLV 328
PA P PP DD++ E GS ++ ++ A +P L L+
Sbjct: 725 -----PALGCPHPPE-------------DDSSLRAERGSLADLPMAPPASAPPEFLDPLM 766
Query: 329 SRMISEGSSPIRCPGQCLSPAPRPPGEPVSPAGGAAQDSQDPEAAAGPGGVELVDMETLC 388
G++ + PG+ PAP PP P P A A P
Sbjct: 767 ------GAAAPQYPGRGPPPAPPPPPPP-------------PRAPADPAA---------S 798
Query: 389 APPPPAPAAPRPGPAQPGPCLFLSN-PTRDTITPLWAAPGRAARPGRACSAACSEEEDEE 447
PP A A+P G + PGP S T +P A PG A EE
Sbjct: 799 PDPPSAVASPGSGLSSPGPKPGDSGYETETPFSPEGAFPG---------GGAAEEEGVPR 849
Query: 448 DDEEEEDAEDSAGSPGGRGTGPSAPRDASLVYDAVKYTLVVDEHTQLELVSLRRCAGLGH 507
E + A P P P L K T VV T+ L+SLR
Sbjct: 850 PRAPPEPPDPGAPRP------PPDPGPLPLPGPREKPTFVVQVSTEQLLMSLR------E 897
Query: 508 DSEEDSGGE--ASEEEAGAALLGGGQVSGDTSP-------------DSPDLTFSKKFLNV 552
D + GE A+ E G G G + + P +P L+ + V
Sbjct: 898 DVTRNLLGEKGATARETGPRKAGRGPGNREKVPGLNRDPTVLGNGKQAPSLSLPVNGVTV 957
Query: 553 FVNSTSRSSSTESFGLFSCLVNGEEREQ 580
N R+ E + + ERE+
Sbjct: 958 LENGDQRAPGIEEKAAENGALGSPEREE 985
Score = 47.0 bits (110), Expect = 7e-05
Identities = 84/379 (22%), Positives = 126/379 (33%), Gaps = 94/379 (24%)
Query: 116 LTTLGAQDSLNNNGGFDLVR-------------PASWQET--------ALCSPAPE-ALR 153
LT ++D ++ NGG R P W++T + PAPE +L
Sbjct: 1023 LTPPKSEDKVSENGGLRFPRNTERPPETGPWRAPGPWEKTPESWGPAPTIGEPAPETSLE 1082
Query: 154 ELPGPLPATDTGPGGAQSPVRPGCDCEGNRPAEPPAPGGTSPSSDPGIEADLRSRSSGGR 213
P P + GG +P P P + + +PG E R+ +GG
Sbjct: 1083 RAPAPSAVVSSRNGGETAP-------------GPLGPAPKNGTLEPGTER--RAPETGGA 1127
Query: 214 GGRRSSQELSSPGSDSEDAGGARLGRMISSISETELELSSDGGSSSSGRSSHL--TNSIE 271
+PG+ D G GR ++ GG SG + ++
Sbjct: 1128 P--------RAPGAGRLDLGSG--GRAPVGTG------TAPGGGPGSGVDAKAGWVDNTR 1171
Query: 272 EASSPASEPEPPREPPRRPAFLPVGPDDTNSEYESGSESEPDLSEDADSPWLLSNLVSRM 331
P P PP PRR + P + E E EP +
Sbjct: 1172 PQPPPPPLPPPPEAQPRR-----LEPAPPRARPEVAPEGEPGAPDSR------------- 1213
Query: 332 ISEGSSPIRCPGQCLSPAPRPPGEP--VSPAGGAAQDSQDPEAAAGPGGVELVDMETLCA 389
+ G + + G P + P P G +S+ +A + +L
Sbjct: 1214 -AGGDTALSGDGDPPKPERKGPEMPRLFLDLGPPQGNSEQIKAR--------LSRLSLAL 1264
Query: 390 PPPPAPAAPRPGPAQPGPCLFLSNPTRDTITPLWAAPGRAARPGRACSAACSEEEDEEDD 449
PP P PGP +P P AA G A G A E+++ED+
Sbjct: 1265 PPLTLTPFPGPGPRRP--------PWEGA--DAGAAGGEAGGAGAPGPAEEDGEDEDEDE 1314
Query: 450 EEEEDAEDSAGSPGGRGTG 468
EE+E+A + G RG G
Sbjct: 1315 EEDEEAAAPGAAAGPRGPG 1333
Score = 36.6 bits (83), Expect = 0.094
Identities = 38/149 (25%), Positives = 57/149 (38%), Gaps = 22/149 (14%)
Query: 58 DDNEEEDDEDEEEEEEEEEGDGEGQEGGDPGSEAPAPGPLIPSPSVEEPHKHRPTTLRLT 117
+D E+ED+++EE+EE G G G PG AP P++ S + + RP L
Sbjct: 1305 EDGEDEDEDEEEDEEAAAPGAAAGPRG--PGRARAAPVPVVVSSA--DADAARPLRGLLK 1360
Query: 118 TLGAQDSLNNNGGFDLVRPASWQETALC------SPAPEALRELPGPLPATDTGPGGAQS 171
+ D ++ + S+ +P E + P P DT P +
Sbjct: 1361 SPRGADEPEDSELERKRKMVSFHGDVTVYLFDQETPTNELSVQAP---PEGDTDPSTPPA 1417
Query: 172 PVRPGCDCEGNRPAEPPAPGGTSPSSDPG 200
P P P PG PS+D G
Sbjct: 1418 P---------PTPPHPATPGDGFPSNDSG 1437
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 55.5 bits (132), Expect = 2e-07
Identities = 100/394 (25%), Positives = 127/394 (32%), Gaps = 73/394 (18%)
Query: 91 APAPGPLIPSP--SVEEPHKHRPTTLRLTTLGAQDSLNNN---------GGFDLVRPASW 139
A APG L P P S P P LR+ LGA ++ GG + A
Sbjct: 19 ARAPGLLTPRPPGSPRPPPPVTPAALRV--LGAAGAVGRKPLAERAGGIGGATIPESAPR 76
Query: 140 QETALCSPAPEALRELPGPLPATDTGPGGAQSPVRPGCDCEGNRPAEPPAPGGTSPSSDP 199
S P + R P PA +T PG SP R G P G S++
Sbjct: 77 AGPTRTSRPPASGRGERAP-PAKNTSPGPVSSPGR----ASGTTRPGPLGQKGLRISAEE 131
Query: 200 ----GIEADLRSRSSGGRGGRRSSQELSSPGSDS------EDAGGARLG----------- 238
G + RS+ G RR + +PG+ S A G +G
Sbjct: 132 TVARGKATEAPKRSALSAGARRDTSG-PTPGTPSPAMARRSRAAGTEVGLPRPAPSARPR 190
Query: 239 -------RMISSISETEL--------ELSSDGGSSSSGRSSHLTNSIEEASSPASEPEPP 283
+ +SS SE S GG S L++S SSPA
Sbjct: 191 PPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSA 250
Query: 284 REPPRRPAFLPVGPDDTNSEYESGSESEPDLSEDADSPWLLSNLVSRMISEGSSPIRCPG 343
R PR PA P P + + P + A + LS SSP+ P
Sbjct: 251 RGTPRAPAH-PSQPKPKGLQALRPPQVTPPRKDAAPALGPLS----------SSPLATPS 299
Query: 344 QCLSPAPRPP-------GEPVSPAGGAAQDSQDPEAAAGPGGVELVDMETLCAPPPPAPA 396
P+P P P +P A P A + + L PPP AP
Sbjct: 300 PSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPP 359
Query: 397 APRPGPAQPGPCLFLSNPTRDTITPLWAAPGRAA 430
A P Q P S P TP AP A
Sbjct: 360 ALALPPLQAPPSPPASPPLSPLATPSPQAPNALA 393
Score = 41.6 bits (96), Expect = 0.003
Identities = 95/367 (25%), Positives = 121/367 (32%), Gaps = 53/367 (14%)
Query: 84 GGDPGSEAPAPGPLIPSPSVEEPHKHRPTTLRLTTLGAQDSLNN--NGGFDLVRPASWQ- 140
G + G PAP P P E P K + +T + + G L RPAS
Sbjct: 175 GTEVGLPRPAPSAR-PRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSL 233
Query: 141 ---ETALCSPA---PEALRELPGPLPATDTGPGGAQSPVRPGCDCEGNRPAEPP-APGGT 193
T L SPA P A P + P G Q+ +RP + A P P +
Sbjct: 234 SSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQA-LRPPQVTPPRKDAAPALGPLSS 292
Query: 194 SPSSDPGIEADLRSRSSGGRGGRRSSQELSSPGSDSEDAGGARLGRMISSISETELELSS 253
SP + P A + S Q L SP + LG + + L
Sbjct: 293 SPLATPSPSAPPSPSAPP------SLQTLPSPPATPPSQATTSLGSPTLQATHSFLP--- 343
Query: 254 DGGSSSSGRSSHLTNSIEEASSPASEPEPPREPPRRPAFLPVGPDDTNSEYESGSESEPD 313
S S L +A PA P + PP PA P+ P T S + +
Sbjct: 344 ------SPPLSPLATPPPQAP-PALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHL 396
Query: 314 LSEDADSPWLLSNLVSRMISEGSSPIRCPGQCLSPAPRPPGEP-VSPAGGAAQDSQDPEA 372
L P S P++ P SP PP P +P A P
Sbjct: 397 LQAPFSPP-------------PSPPVQAP---FSPPASPPVSPSATPPSQAPPSLAAPPL 440
Query: 373 AAGPGGVELVDMETLCAPPPPAP---AAPRPGPAQPGPCLFLSNPTRDTITPLWAAPG-R 428
P M PPP AP AAP A+P P P PL A P
Sbjct: 441 QVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPP----QAPPALATPPLQALPSPP 496
Query: 429 AARPGRA 435
A+ PG+A
Sbjct: 497 ASFPGQA 503
Score = 40.4 bits (93), Expect = 0.007
Identities = 43/134 (32%), Positives = 56/134 (41%), Gaps = 22/134 (16%)
Query: 136 PASWQETALCSPAPE-ALRELPG-PLP-ATDTGPGGAQSPVRPGCDCEGNRPAEPPAPGG 192
PA+W PAP A R PG PLP TGPG A + + EG A P APG
Sbjct: 629 PAAWSR----GPAPPLAFRGAPGAPLPWPPATGPGSADG-LCTIYETEGPESATP-APGA 682
Query: 193 TSPSSDPGIEADLRSRSSGGRGGRRSSQELSSPGSDSEDAGGARLGRMISSI-----SET 247
P PG +SGG+ + SS G LG + +S+ S T
Sbjct: 683 LDPGPSPG--------TSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRT 734
Query: 248 ELELSSDGGSSSSG 261
L +++G + SG
Sbjct: 735 LLLAAAEGAAGGSG 748
Score = 37.7 bits (86), Expect = 0.042
Identities = 92/390 (23%), Positives = 121/390 (31%), Gaps = 42/390 (10%)
Query: 91 APAPGPLIPSPSVEEPHKHRPTTLRLTTLGAQDSLNNNGGFDLVRPASWQETALCSPAPE 150
APA GPL SP P+ +L S P S T+L SP +
Sbjct: 284 APALGPLSSSPLATPSPSAPPSPSAPPSLQTLPS-------PPATPPSQATTSLGSPTLQ 336
Query: 151 ALRE-LPGP--LPATDTGPGGAQSPVRPGCDCEGNRPAEPP-APGGT-SPSSDPGIEADL 205
A LP P P P + P + PA PP +P T SP + + L
Sbjct: 337 ATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHL 396
Query: 206 RSRSSGGRGGRRSSQELSSPGSDSEDAGGARLGRMISSISETELELSSDGGSSSSGRSSH 265
S P S + S++ L++ +S S
Sbjct: 397 LQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPS- 455
Query: 266 LTNSIEEASSPASEPEPPREPPRRPAFLPVGPDDTNSEYESGSESEPDLSEDADSPWLLS 325
A+ P P P PP + A P + + P S +P+
Sbjct: 456 -------ATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPF--- 505
Query: 326 NLVSRMISEGSSPIRCPGQCLSPAPRPPGEPVSPAGGAAQDSQDPEAAAGPGGVELVDME 385
S S SP+ P P P V P+ A+ Q P PG V
Sbjct: 506 ---SPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGP 562
Query: 386 TLC---APPPPAPAAPRPGPAQPGPCLFLSNPTRDTITPLWAAPGRAARPGRACSAACSE 442
L AP PP P + P GP L + + T TP R G AA S
Sbjct: 563 RLTLALAPGPPPPPSRSPSSTLSGPDL-AGHSSSATSTP---EELRGYDSGPEGGAAAS- 617
Query: 443 EEDEEDDEEEEDAEDSAGSPGGRGTGPSAP 472
DAE +A P GP+ P
Sbjct: 618 --------PPPDAELAACHPAAWSRGPAPP 639
Score = 35.8 bits (81), Expect = 0.16
Identities = 48/160 (30%), Positives = 58/160 (36%), Gaps = 37/160 (23%)
Query: 340 RCPGQCLSPAPRPPGEPVSP------------AGGAAQDSQDPEAAAGPGGVELVDMETL 387
R PG PRPPG P P A GA E A G GG + +
Sbjct: 20 RAPGLL---TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPR 76
Query: 388 CAP-----PPPAPAAPRPGPAQ---PGPCLFLSNPTRDTITPLWAAPGRAARPGRACSAA 439
P PP + R PA+ PGP +S+P R + T PG + G SA
Sbjct: 77 AGPTRTSRPPASGRGERAPPAKNTSPGP---VSSPGRASGT---TRPGPLGQKGLRISA- 129
Query: 440 CSEEEDEEDDEEEEDAEDSAGSPGGR----GTGPSAPRDA 475
EE + E + SA S G R G P P A
Sbjct: 130 ---EETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPA 166
Score = 33.5 bits (75), Expect = 0.80
Identities = 37/137 (27%), Positives = 47/137 (34%), Gaps = 22/137 (16%)
Query: 277 ASEPEPPREPPRRPAFLPVGPDDTNSEYESGSESEPDLSEDADSPWLLSNLVSRMISEGS 336
A P PP P R P+ GPD + S + S P+ DS EG
Sbjct: 567 ALAPGPPPPPSRSPSSTLSGPDLAG--HSSSATSTPEELRGYDSG-----------PEGG 613
Query: 337 SPIRCPGQCLSPAPRP------PGEPVSPAGGAAQDSQDPEAAAGPGGVELVDMETLCAP 390
+ P A P P P++ G P A GPG + + T+
Sbjct: 614 AAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPAT-GPGSAD--GLCTIYET 670
Query: 391 PPPAPAAPRPGPAQPGP 407
P A P PG PGP
Sbjct: 671 EGPESATPAPGALDPGP 687
>gi|7705318 GULP, engulfment adaptor PTB domain containing 1 [Homo
sapiens]
Length = 304
Score = 55.1 bits (131), Expect = 3e-07
Identities = 39/132 (29%), Positives = 69/132 (52%), Gaps = 7/132 (5%)
Query: 656 FDVQFLGSVEVPCHQGNGILCAAMQKIATAR--KLTVHLRPPASCDLEISLRGVKLSLSG 713
++ +FLGS EV +G ++ A++K+ AR K + + P +L+IS+ GVK+
Sbjct: 27 YNAKFLGSTEVEQPKGTEVVRDAVRKLKFARHIKKSEGQKIP-KVELQISIYGVKIL--- 82
Query: 714 GGPEFQRCSHFFQMKNISFCGCHPRNSCYFGFITKHPLLSRFACHVFVSQESMRPVAQSV 773
P+ + H Q+ ISFC + F FI K ++ C+VF S++ + ++
Sbjct: 83 -EPKTKEVQHNCQLHRISFCADDKTDKRIFTFICKDSESNKHLCYVFDSEKCAEEITLTI 141
Query: 774 GRAFLEYYQEHL 785
G+AF Y++ L
Sbjct: 142 GQAFDLAYRKFL 153
>gi|239753314 PREDICTED: similar to RIKEN cDNA C230030N03 [Homo
sapiens]
Length = 1183
Score = 55.1 bits (131), Expect = 3e-07
Identities = 119/473 (25%), Positives = 162/473 (34%), Gaps = 92/473 (19%)
Query: 62 EEDDEDEEEEEEEEEGDGE-GQEGGDPGSEAPAPGPLIPSPSVEEPHKHRPTTLRLTTLG 120
EE + E G GE G E G A A G P++E P P LR G
Sbjct: 660 EEPPGERLRGESRSSGSGERGPEEAPEGGAAAARGQRPRVPALEPPQP--PRGLRK---G 714
Query: 121 AQDSLNNNGGFDLVRPASWQETALCSPAPEALRELPGPLPATDT-----GPGGAQSPVRP 175
AQ+ RP + T+ P A E PG +PA T G G + R
Sbjct: 715 AQEPGK--------RPTFSKVTSFRKGRPLAT-ESPGGVPAPTTEGRRWGSSGPEGLPRE 765
Query: 176 GCDCEGNRPAEPPAPGGTS--PSSDPGIEADLRSRSSGGRGGRRSSQELSSPGSDSEDAG 233
R A P G S P P D R+ G G +S +L S G SE
Sbjct: 766 NPPAAAGRDAPPLHHGDASAWPEFVPQAAGD-RTAGPAGAGHTGTSGDLGSRGPSSESCN 824
Query: 234 GARLGRMISSISETELELSSDGGSSSSGRSSHLTNSIEEA--------SSPASEPEPPR- 284
RL TE +L + + S+ + + + E SSP E E R
Sbjct: 825 AKRL-------KTTEKKLRARLALAHKTFSNFIESIVLEKENTHERSPSSPKGEKEKSRL 877
Query: 285 --------------EPPRRPAF--LPVGPD-----DTNSEYESGSESEPDL------SED 317
P++P LP+GP+ +T+S E +E + +
Sbjct: 878 RQGSWRAFLKSKDAGSPKKPTLVSLPLGPEVLSPAETDSHCEERAEDKEGYVFSDHWAPP 937
Query: 318 ADSPWLLSNLVSRMISEGSSP-IRCP-----GQCLSPAPRP-------PGEPVSPAGGAA 364
S L S+LVS S P I+C G+ L P PG P + G A
Sbjct: 938 LASTPLSSSLVSPEHRRKSEPTIKCTATQEGGRYLPSGIFPEKSWLASPGSPRAQQAGIA 997
Query: 365 QDSQDPEAAAGPGGVELVDMETLCAPPPPAPAAPRPG--------PAQPGPCLFLSNPTR 416
A + + T C P P P +PRP P + +S +
Sbjct: 998 HTLPSSSACC----LAYENPGTPCRPTSPKPLSPRPSAQRMGLHYPGRGSAISMVSLGSY 1053
Query: 417 DTITPLWAAPGRAARPGRACSAACSEEEDEEDDEEEEDAEDSAGSPGGRGTGP 469
+ P R P S S + +D+++EE E G P G GT P
Sbjct: 1054 SYVDSSSGDPERPKIPKGQTSFLLSLQTLNQDEQKEESREGGQG-PRGLGTVP 1105
Score = 40.8 bits (94), Expect = 0.005
Identities = 77/353 (21%), Positives = 121/353 (34%), Gaps = 58/353 (16%)
Query: 146 SPAPEALRELPGPLPATDTGPGGAQSPVRPGCDCEGNRPAEPPAPG----------GTSP 195
SPAP +L GP+PA +G Q P +PG + P+ G S
Sbjct: 380 SPAPT---QLSGPIPAFQSGAPHLQGPCKPGGFRLQRASQDTPSAGLLGENQLRQDSRSC 436
Query: 196 SSDPGIEADLRSRSSGGRGGRRSSQELSSPGSDSEDAGGARLGRMISSISETELEL---S 252
+ ++L S+ + SP S +++ G +L + ET+ L S
Sbjct: 437 LVASCLTSELVKLSAEEVPEPAECKSEQSPESRTQEPQGTQLAPRAADERETQKHLWGIS 496
Query: 253 SDGGSSSSGRSSHLTNSIEEASSPASEPEPPREPPRRPAFLPVG--------PDDTNSEY 304
G+ +S +S S EE+ SP + + PR+P + G D +++
Sbjct: 497 VQAGNQTSNYTSKYVLS-EESKSP-TRAKFPRQPSSEGTQVWSGDLMGCLEVSDSSDAPE 554
Query: 305 ESGSESEPDLSEDADSPWLLSNLVSRMISEGSSPIRCP-----GQCLSPAPRPPGEPVSP 359
+ S D S+ A+ +L + +G S + G + PG +P
Sbjct: 555 TTQKSSAIDTSKAAEEAMVLDPIYREQALQGLSEFKAATVSHCGPGAEEGEQGPGGGKTP 614
Query: 360 AGGAAQDSQDPEAAAGPGGVELVDMETLCAPPPPAPAAPRPGPAQPGPCLFLSNPTRDTI 419
AG + P AG G ++ V AA P+ P
Sbjct: 615 AGNECELPAAPIQGAGDGALQRVAQAAELGRVLVPQAASEETPSTEEP------------ 662
Query: 420 TPLWAAPGRAARPGRACSAACSEEEDEEDDEEEEDAEDSAGSPGGRGTGPSAP 472
PG R G + S+ E EE E G+ RG P P
Sbjct: 663 ------PGERLR-GESRSSGSGERGPEEAPE--------GGAAAARGQRPRVP 700
>gi|116256464 hypothetical protein LOC343990 [Homo sapiens]
Length = 962
Score = 54.7 bits (130), Expect = 3e-07
Identities = 91/370 (24%), Positives = 130/370 (35%), Gaps = 65/370 (17%)
Query: 61 EEEDDEDEEEEEEEEEGDGEGQEGGDPGSEAPAPGPLIPSPSVEEPHKHRPTTLRLTTLG 120
EEE++E E EE GQ+ P P PGP P P P R RL
Sbjct: 261 EEENEEKPLLEVSPEERPSSGQQDVAP-DRGPEPGPPAPLP---PPGGARARRARLQHSS 316
Query: 121 AQDSLNNNGGFDLVRPASWQETALCSPAPEALRELPGPLPATDTGPGGAQSPVRPGCDCE 180
A + GG P+S PA L E P + P PG D
Sbjct: 317 ALTASVEEGGVPGEDPSS-------RPATPELAEPESAPTLRVEPPSPPEGPPNPGPD-G 368
Query: 181 GNRPAEPPAPGGTSPSSDPGIEADLRSRSSGGRGGRRSSQELSSPGSDSEDAGGARLGRM 240
G + E P G +P++D E + ++++SP + G
Sbjct: 369 GKQDGEAPPAGPCAPATDKAEEVVC------------APEDVASPFPTAIPEGD------ 410
Query: 241 ISSISETELELSSDGGSSSSGRSSHLTNSIEEASSPASEPEPPREPPRRPAFLPVGPDDT 300
++ ET+ +S+ S+ G + E +P P+ + PP PA P +T
Sbjct: 411 -TTPPETDPAATSEAPSARDGPERSVPKEAE--PTPPVLPDEEKGPP-GPAPEPEREAET 466
Query: 301 NSEYESGSE-----SEPDLSEDADSPWLLSNLVSRMISEGSSPIRCPGQCLSPAPRPPGE 355
E +G+E +EP + P S L R + P P L+ A PP E
Sbjct: 467 EPERGAGTEPERIGTEPSTAPAPSPPAPKSCLKHRPAAASEGPAASPP--LAAAESPPVE 524
Query: 356 P--------------------VSPAGGAAQDSQDPEAAAGPGGVELVDMETLCAPPPPAP 395
P +P GA + + PE A GG EL +
Sbjct: 525 PGPGSLDAEAAAPERPKAERAEAPPAGAERAA--PERKAERGGAELRGAKKFSV--SSCR 580
Query: 396 AAPRPGPAQP 405
A PRPG ++P
Sbjct: 581 ARPRPGVSRP 590
Score = 41.6 bits (96), Expect = 0.003
Identities = 85/332 (25%), Positives = 111/332 (33%), Gaps = 49/332 (14%)
Query: 145 CSPAPEALRELPGPLPATDTGPGGAQSPVRPGCDCEGNRPAEPPAPGGTSP--SSDPGIE 202
C+P E E P + + P Q V P E PA P PGG +
Sbjct: 257 CTPEEEENEEKPLLEVSPEERPSSGQQDVAPDRGPEPGPPAPLPPPGGARARRARLQHSS 316
Query: 203 ADLRSRSSGGRGGRRSSQELSSPG-SDSEDAGGARLGRMISSISETELELSSDGGSSS-- 259
A S GG G S ++P ++ E A R+ S E DGG
Sbjct: 317 ALTASVEEGGVPGEDPSSRPATPELAEPESAPTLRVEP--PSPPEGPPNPGPDGGKQDGE 374
Query: 260 ---SGRSSHLTNSIEEASSPASEPEPPREPPRRPAFLPVGPDDTNSEYESGSESEPDLSE 316
+G + T+ EE PE P P +P G D T E + + SE +
Sbjct: 375 APPAGPCAPATDKAEEV---VCAPEDVASP--FPTAIPEG-DTTPPETDPAATSEAPSAR 428
Query: 317 DADSPWLLSNLVSRMISEGSSPIRCPGQCLSPAPRPPGEPVSPAGGAAQDSQDPEAAAGP 376
D R + + + P P PPG P A +PE AG
Sbjct: 429 DGP---------ERSVPKEAEP--TPPVLPDEEKGPPGPAPEPEREA---ETEPERGAGT 474
Query: 377 GGVEL-VDMETLCAPPPPAPAA---PRPGPAQPGPCLFLSNPTRDTITPLWAAPGRAARP 432
+ + T AP PPAP + RP A GP ++P PL AA P
Sbjct: 475 EPERIGTEPSTAPAPSPPAPKSCLKHRPAAASEGPA---ASP------PLAAAESPPVEP 525
Query: 433 GRACSAACSEEEDEEDDEEEEDAEDSAGSPGG 464
G A E E AE + P G
Sbjct: 526 GPGSLDA------EAAAPERPKAERAEAPPAG 551
Score = 34.7 bits (78), Expect = 0.36
Identities = 90/442 (20%), Positives = 137/442 (30%), Gaps = 45/442 (10%)
Query: 65 DEDEEEEEEEEEGDG-EGQEGGDPGSEAPAPGPLIPSPSVEEPHKHRPTT-----LRLTT 118
+ + E E E E G G E + G S APAP P P + KHRP
Sbjct: 459 EPEREAETEPERGAGTEPERIGTEPSTAPAPSPPAPKSCL----KHRPAAASEGPAASPP 514
Query: 119 LGAQDSLNNNGGFDLVRPASWQETALCSPAPEALRELPGPLPATDTGPGGAQSPVRPGCD 178
L A +S G P S A P+A R P A P + R G +
Sbjct: 515 LAAAESPPVEPG-----PGSLDAEAAAPERPKAERAEAPPAGAERAAP--ERKAERGGAE 567
Query: 179 CEGNRP------AEPPAPGGTSPSSDPGIEADLRSRSSGGRGGRRSSQELSSPGSDSEDA 232
G + P PG + P L R P
Sbjct: 568 LRGAKKFSVSSCRARPRPGVSRPLERASGRLPLARSGPVWRSEAALDDLQGLPEPQHAKP 627
Query: 233 GGARLGRMISSISETELELSSDGGSSSSGRSSHLTNSIEEASSPASEPEPPREPPRRPAF 292
G +L ++ +S G S + + E A EP P + R P
Sbjct: 628 GPRKLAE--RGPQDSGDRAASPAGPRKSPQEAAAAPGTREPCPAAQEPAPSED--RNPFP 683
Query: 293 LPVGPDDTNSEYESGSESEPDLSEDADSPWLLSNLVSRMISEGSSPIRCPGQCLSPAPRP 352
+ + + +Y G+ E + + L ++ + E P+ +PA R
Sbjct: 684 VKLRSTSLSLKYRDGASQEVKGVKRYSAEVRLERSLTVLPKEEKCPLG-----TAPALRG 738
Query: 353 PGEPVSPAGGAAQDSQDPEAAAGPGGVELVDMETLCAPPPPAPAAPRPGPAQP--GPCLF 410
P G A+ + + L+ TL P PAP PG +P P
Sbjct: 739 TRAPSDQGKGKARPPEPLSSKPPLPRKPLLQSFTL--PHQPAPPDAGPGEREPRKEPRTA 796
Query: 411 LSNPTR----DTITPLWAAPGRAARPGRACSAACSEE-----EDEEDDEEEEDAEDSAGS 461
P R ++ P PG +P ++ + + E++ A
Sbjct: 797 EKRPLRRGAEKSLPPAATGPGADGQPAPPWITVTRQKRRGTLDQPPNQEDKPGARTLKSE 856
Query: 462 PGGRGTGPSAPRDASLVYDAVK 483
PG + P ++ D V+
Sbjct: 857 PGKQAKVPERGQEPVKQADFVR 878
Score = 31.6 bits (70), Expect = 3.0
Identities = 76/316 (24%), Positives = 95/316 (30%), Gaps = 111/316 (35%)
Query: 271 EEASSPASEPEPPREPPRRPAFLPVGP---------------DDTNSEYESGSESEP--D 313
E+A + + PR PP VGP D T S S + P D
Sbjct: 149 EDAGMSSEDDGLPRSPPEMSLLHDVGPGTTIKVSVVSPDHVSDSTVSARISDNSLAPVAD 208
Query: 314 LSEDADSPWLLSN---------------------LVSRMISEGSSPIRC----------P 342
S A+S L N L SR SE S + C P
Sbjct: 209 FSYPAESSSCLDNSAAKHKLQVKPRNQRSSKMRRLSSRAQSESLSDLTCTPEEEENEEKP 268
Query: 343 GQCLSPAPRP----------------PGEPVSPAGGA------AQDSQDPEAAAGPGGV- 379
+SP RP P P+ P GGA Q S A+ GGV
Sbjct: 269 LLEVSPEERPSSGQQDVAPDRGPEPGPPAPLPPPGGARARRARLQHSSALTASVEEGGVP 328
Query: 380 -----------ELVDMETL----CAPPPPAPAAPRPGP--------AQP-GPCLFLSNPT 415
EL + E+ PP P P PGP A P GPC ++
Sbjct: 329 GEDPSSRPATPELAEPESAPTLRVEPPSPPEGPPNPGPDGGKQDGEAPPAGPCAPATDKA 388
Query: 416 -------RDTITPL-WAAPGRAARPGRACSAACSEEEDEEDDEEEEDAEDSAGSP----- 462
D +P A P P AA SE D E +++ +P
Sbjct: 389 EEVVCAPEDVASPFPTAIPEGDTTPPETDPAATSEAPSARDGPERSVPKEAEPTPPVLPD 448
Query: 463 ---GGRGTGPSAPRDA 475
G G P R+A
Sbjct: 449 EEKGPPGPAPEPEREA 464
>gi|149158690 HLA-B associated transcript-2 [Homo sapiens]
Length = 2157
Score = 54.3 bits (129), Expect = 4e-07
Identities = 104/440 (23%), Positives = 135/440 (30%), Gaps = 119/440 (27%)
Query: 50 DFQEFEMIDDNEEEDDEDEEEEE----------EEEEGDGEGQEGGDPGSEAPAPGPLIP 99
D+ E D E+ D DEE E EE + +G++G P SE P P
Sbjct: 334 DYTEKLKFSDEEDGRDSDEEGAEGHRDSQSASGEERPPEADGKKGNSPNSEPPTP----- 388
Query: 100 SPSVEEPHKHRPTTLRLTTLGAQDSLNNNGGFDLVRPASWQETALCSPAPEALRELPGPL 159
T A+ S RP ET PAP+ PL
Sbjct: 389 -----------------KTAWAETS----------RPP---ETEPGPPAPKP------PL 412
Query: 160 PATDTGPGGAQSPVRPGCDCEGNRPAEPPAPGGTSPSSDPGIEADLRSRSSGG------R 213
P GP G P D G P +PPAP + R +SS R
Sbjct: 413 PPPHRGPAGNWGPPGDYPD-RGGPPCKPPAP-----EDEDEAWRQRRKQSSSEISLAVER 466
Query: 214 GGRRSSQELSSPGSDSEDAGGARLGRMISSISETELELSSDGGSSSSGRSSHLTNSIEEA 273
RR +E + A +L R+ + L ++ + +
Sbjct: 467 ARRRREEEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAA-----------P 515
Query: 274 SSPASEPEPPREPPRRPAFLPVGPDDTNSEYESGSESEPDLSEDADSPWLLSNLVS---- 329
S+PA P P+E P PA P +E E +++ P S LVS
Sbjct: 516 STPAPPPAVPKELPAPPAPPPASAPTPETEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGS 575
Query: 330 -RMISEGS---SPIRC---------PGQCLSPAPRPPGEPVSPAG-GAAQDSQDPEAAAG 375
S GS SP+ P + + P PP V P G G Q P G
Sbjct: 576 TSSTSSGSFEASPVEPQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLG 635
Query: 376 --------PGGVELVDMETL---------------CAPPPPAPAAPRPGPAQPGPCLFLS 412
P + E L APP P P P P QP +
Sbjct: 636 YPKYQKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPVP----PSPPQPVTLGAVP 691
Query: 413 NPTRDTITPLWAAPGRAARP 432
P P PG RP
Sbjct: 692 APQAPPPPPKALYPGALGRP 711
Score = 37.7 bits (86), Expect = 0.042
Identities = 61/235 (25%), Positives = 87/235 (37%), Gaps = 31/235 (13%)
Query: 84 GGDPGSEAPAP-GPLIPSPSVEEPHKHRPTTLRLTTLGAQDSLNNNGGFDLVRPASWQET 142
GG P + P P PSP P ++ P + + L + G + +++
Sbjct: 1494 GGHPRHKPGLPQAPQGPSP--RPPTRYEPQRVN-SGLSSDPHFEEPGPMVRGVGGTPRDS 1550
Query: 143 ALCSPAPEALRELPGPLPATDTGPGGAQSPVRPGCDCEGNRPAEPPAPGGTSPSSDPGIE 202
A SP P RE P P Q P G ++P PG + S D G E
Sbjct: 1551 AGVSPFPPKRRERPPRKPEL------LQEESLPPPHSSGFLGSKPEGPGPQAESRDTGTE 1604
Query: 203 A------DLRSRSSGGRGGRRSSQE-LSSPGSDSEDAGGARLGRMISSISET-ELELSSD 254
A + ++ + R SS E P S ED G + + S + + + ++SS
Sbjct: 1605 ALTPHIWNRLHTATSRKSYRPSSMEPWMEPLSPFEDVAGTEMSQSDSGVDLSGDSQVSSG 1664
Query: 255 GGSSSSGRSSHLTNSIEE------ASSPAS----EPEPPREPPRRPAFLPVGPDD 299
S S L + E SSP + E P EPPRRP P P D
Sbjct: 1665 PCSQRSSPDGGLKGAAEGPPKRPGGSSPLNAVPCEGPPGSEPPRRP---PPAPHD 1716
Score = 35.8 bits (81), Expect = 0.16
Identities = 65/281 (23%), Positives = 89/281 (31%), Gaps = 44/281 (15%)
Query: 53 EFEMIDDNEEEDDEDEEEEEEEEEGDGEGQEGGDPGSEAPAPGPLIPSPSVEEPHKHRPT 112
E+E I + + E E + +E P PL P P P P
Sbjct: 1093 EYEEIPKRRRQRGSETGSETHESDLAPSDKEAPTPKEGTLTQVPLAPPPPGAPPS---PA 1149
Query: 113 TLRLTTLGAQ-------DSLNNNGGFDLVRPASWQETALCSPAPEALRELP--GPLPATD 163
R T G + S GG RP PA + P GPLP +
Sbjct: 1150 PARFTARGGRVFTPRGVPSRRGRGGG---RPPPQVCPGWSPPAKSLAPKKPPTGPLPPSK 1206
Query: 164 TGPGGAQSPVRPGCDCEGNRPAEPPAPGGTSPSSDPGIEADLRSRSSGGRGGRRSSQELS 223
+ + PG P P A GG++ S+ G+E R R R GR Q+
Sbjct: 1207 EP---LKEKLIPG-------PLSPVARGGSNGGSNVGMEDGERPRRR--RHGRAQQQD-- 1252
Query: 224 SPGSDSEDAGGARLGRMISSISETELELSSDGGSSSSGRSSHLTNSIEEASSPASEPEPP 283
+ R E E G S + E ++ P P
Sbjct: 1253 ------------KPPRFRRLKQERENAARGSEGKPSLTLPASAPGPEEALTTVTVAPAPR 1300
Query: 284 REPPRRPAFLPVGPDDTNSEYESGSESEPDLSE---DADSP 321
R + P D N E+E+ SES SE D ++P
Sbjct: 1301 RAAAKSPDLSNQNSDQANEEWETASESSDFTSERRGDKEAP 1341
Score = 34.7 bits (78), Expect = 0.36
Identities = 92/405 (22%), Positives = 127/405 (31%), Gaps = 107/405 (26%)
Query: 72 EEEEEGDGEGQEGGDPGSEAPA--PGPLIPSPSVEEPHKHRPTTLRLTTLGAQDSLNNNG 129
++E E G EG P PA PGP +V R + L Q+S N
Sbjct: 1261 KQERENAARGSEG-KPSLTLPASAPGPEEALTTVTVAPAPRRAAAKSPDLSNQNSDQANE 1319
Query: 130 GFDLVRPAS--WQETALCSPAPEALRELPGPLPATDTGPGGAQ----------------- 170
++ +S E AP + P + G GGA
Sbjct: 1320 EWETASESSDFTSERRGDKEAPPPVLLTPKAVGTPGGGGGGAVPGISAMSRGDLSQRAKD 1379
Query: 171 ------SPVRPGCDCEGNRPAEPPAPGGTSPSSDPGIEADLRSRSSGGRGGRRS------ 218
S RPG + + RP P G+S SS G R+ GRG +RS
Sbjct: 1380 LSKRSFSSQRPGMERQNRRPG-PGGKAGSSGSSSGGGGGGPGGRTGPGRGDKRSWPSPKN 1438
Query: 219 --------SQELSSPGSDSEDAGGARLGRMISS----ISETELELSSDGGS--SSSGRSS 264
L P + RL ++I S I + +LSS GS + G
Sbjct: 1439 RSRPPEERPPGLPLPPPPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGSVTAPGGHPR 1498
Query: 265 HLTNSIEEASSPASEPEPPREPPRRPAFLPVGPDDTNSEYESGSESEPDLSEDADSPWLL 324
H + P+ P EP R SG S+P E
Sbjct: 1499 HKPGLPQAPQGPSPRPPTRYEPQR---------------VNSGLSSDPHFEEPG------ 1537
Query: 325 SNLVSRMISEGSSPIRCPGQCLSPAP-----RPPGEPVSPAGGAAQDSQDPEAAAGPGGV 379
+ G +P G +SP P RPP +P
Sbjct: 1538 ----PMVRGVGGTPRDSAG--VSPFPPKRRERPPRKP----------------------- 1568
Query: 380 ELVDMETLCAPPPPAPAAPRPGPAQPGPCLFLSNPTRDTITP-LW 423
EL+ E+L PPP + P PGP + + +TP +W
Sbjct: 1569 ELLQEESL--PPPHSSGFLGSKPEGPGPQAESRDTGTEALTPHIW 1611
Score = 32.7 bits (73), Expect = 1.4
Identities = 67/274 (24%), Positives = 88/274 (32%), Gaps = 39/274 (14%)
Query: 147 PAPEALRELPG-PLPATDTGPGGAQSPVRPGCDCEGNRPAEPPAPGGTSPSSDPGIEADL 205
P P + ELP PL D P + + P E P G SP+ P + D
Sbjct: 956 PPPTKVEELPPKPLEQGDETPKPPKPDPLKITKGKLGGPKETPPNGNLSPA--PRLRRDY 1013
Query: 206 RSRSSGG---RGGRRSSQELSSPGSDSEDAGGARLGRMISSISETELELSSDGGSSSSGR 262
G RG R G G R R S E G + G
Sbjct: 1014 SYERVGPTSCRGRGRGEYFARGRGFRGTYGGRGRGARSREFRSYREFRGDDGRGGGTGGP 1073
Query: 263 SSHLTNSIEEASSPASEPEPPREPPRRPAFLPVGPDDTNSEYESGSES-EPDLS-EDADS 320
+ AS SE E P+R E+GSE+ E DL+ D ++
Sbjct: 1074 NHPPAPRGRTASETRSEGSEYEEIPKRRR---------QRGSETGSETHESDLAPSDKEA 1124
Query: 321 PWLLSNLVSRMISEGSSPIRCPGQCLSPAPRPPGEPVSPA-------GGAAQDSQDPEAA 373
P ++++ P+ AP PPG P SPA GG + +
Sbjct: 1125 PTPKEGTLTQV------PL---------APPPPGAPPSPAPARFTARGGRVFTPRGVPSR 1169
Query: 374 AGPGGVELVDMETLCAPPPPAPAAPRPGPAQPGP 407
G GG PP AP+ P P P
Sbjct: 1170 RGRGGGRPPPQVCPGWSPPAKSLAPKKPPTGPLP 1203
Score = 32.0 bits (71), Expect = 2.3
Identities = 96/396 (24%), Positives = 129/396 (32%), Gaps = 83/396 (20%)
Query: 147 PAPEALRELPGPLPAT-DTGPGGAQSPV----------RPG-CDCEGNRPAEPPAPG--- 191
P P+ L+ G L +T P G SP R G C G E A G
Sbjct: 979 PKPDPLKITKGKLGGPKETPPNGNLSPAPRLRRDYSYERVGPTSCRGRGRGEYFARGRGF 1038
Query: 192 -GTSPSSDPGIEA-DLRS----RSSGGRGGR------------RSSQELSSPGSDSEDAG 233
GT G + + RS R GRGG R++ E S GS+ E+
Sbjct: 1039 RGTYGGRGRGARSREFRSYREFRGDDGRGGGTGGPNHPPAPRGRTASETRSEGSEYEEIP 1098
Query: 234 GARLGRMISSISET-ELELSSDGGSSSSGRSSHLTNSIEEASSPASEPEPPREPPRRPA- 291
R R + SET E +L+ + + + LT P + P P P R A
Sbjct: 1099 KRRRQRGSETGSETHESDLAPSDKEAPTPKEGTLTQVPLAPPPPGAPPSPA--PARFTAR 1156
Query: 292 ----FLPVGPDDTNSEYESGSESEPDLSEDADSPWLLSNLVSRMISEGSSPIRCPGQCLS 347
F P G G P + P ++ +P + P L
Sbjct: 1157 GGRVFTPRGVPSRRGR--GGGRPPPQVCPGWSPP-----------AKSLAPKKPPTGPLP 1203
Query: 348 PAPRPPGEPVSPAGGAAQDSQDPEAAAGPGGVELVDMETLCAP-------------PP-- 392
P+ P E + P P A G G V ME P PP
Sbjct: 1204 PSKEPLKEKLIPG------PLSPVARGGSNGGSNVGMEDGERPRRRRHGRAQQQDKPPRF 1257
Query: 393 -----PAPAAPRPGPAQPGPCLFLSNP-TRDTITPLWAAPGRAARPGRACSAACSEEEDE 446
A R +P L S P + +T + AP A R A S S + +
Sbjct: 1258 RRLKQERENAARGSEGKPSLTLPASAPGPEEALTTVTVAP--APRRAAAKSPDLSNQNSD 1315
Query: 447 EDDEEEEDAEDSAGSPGGRGTGPSAPRDASLVYDAV 482
+ +EE E A +S+ R AP L AV
Sbjct: 1316 QANEEWETASESSDFTSERRGDKEAPPPVLLTPKAV 1351
>gi|189181750 human immunodeficiency virus type I enhancer binding
protein 3 b [Homo sapiens]
Length = 2405
Score = 54.3 bits (129), Expect = 4e-07
Identities = 89/347 (25%), Positives = 127/347 (36%), Gaps = 59/347 (17%)
Query: 53 EFEMIDDNEEEDDEDEEEEEEEEEGDGEGQEGGDPGSEAPAPGPLIPSPSVEEPHKHRPT 112
+F ++D++ + D DE+E+E+EEE E P SEAP PGP PH R
Sbjct: 1846 QFSDLEDSDSDSDLDEDEDEDEEESQDELSR---PSSEAPPPGP---------PHALRAD 1893
Query: 113 TLRLTTLGAQDSLNNNGGFDLVRPASWQE-----TALCSPAPEALRELP--GPLP----A 161
+ + LG Q G + R +S E + CS + +++ LP GP P
Sbjct: 1894 SSPI--LGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVE 1951
Query: 162 TDTGPGGAQSPVRPGCDCEGNRPA--EPP------------APGGTSPSSDPGIEADLRS 207
DTG + PV P ++ A PP +P SP+ +P A
Sbjct: 1952 KDTGSALSYKPVSPRRPWSPSKEAGSRPPLARKHSLTKNDSSPQRCSPAREPQASAPSPP 2011
Query: 208 RSSGGRGGRRSSQELSSPGSDSEDAGGARLGRMISSISETELELSSDGGSSSSGRSSHLT 267
G + SP LGR ++ + LS G++ G +
Sbjct: 2012 GLHVDPGRGMGALPCGSPRLQLSPLTLCPLGRELAPRAHV---LSKLEGTTDPGLPRY-- 2066
Query: 268 NSIEEASSPASEPEPPRE-PPRRPAFLPVGPDDTNSEYESGSESEPDLSEDADSPWLLSN 326
S SP PPR PP + A GP S E P L D + +
Sbjct: 2067 -SPTRRWSPGQAESPPRSAPPGKWAL--AGPGS-----PSAGEHGPGLGLDPRVLFPPAP 2118
Query: 327 LVSRMISEGSSPIRCPGQCLSPAPRPPGEPVSPAGGAAQDSQDPEAA 373
L +++S R P C SP P G A S P +A
Sbjct: 2119 LPHKLLS------RSPETCASPWKAESRSPSCSPGPAHPLSSRPFSA 2159
Score = 41.6 bits (96), Expect = 0.003
Identities = 82/337 (24%), Positives = 114/337 (33%), Gaps = 49/337 (14%)
Query: 71 EEEEEEGDGEGQEGGD-PGSEAPAPGPLIPSPSVEEPHKHRPTTLRLTTLGAQDSLNNNG 129
E+ + G EG D P ++ P+P P +P H +P +R + + L
Sbjct: 807 EKSDSLEQPSGLEGEDKPLAQFPSPPP---APHGRSAHSLQPKLVRQPNIQVPEILVTE- 862
Query: 130 GFDLVRPASWQETALCSPAPEALRELPGP--------LPATDTGPGGAQSPVRPGCDCEG 181
+ RP + E PE E P LPA P + + G
Sbjct: 863 --EPDRPDTEPEPP--PKEPEKTEEFQWPQRSQTLAQLPAEKLPPKKKRLRLAEMAQSSG 918
Query: 182 NRPAEPPAPGGTSPSSDPGIEADLRSRSSGGRGGRRSSQELSSPGSD--SEDAGGARLGR 239
E P SPS + + SRS+ E SP SD + G L
Sbjct: 919 ESSFESSVPLSRSPSQESNVSLSGSSRSASFERDDHGKAEAPSPSSDMRPKPLGTHMLTV 978
Query: 240 MISSISETELELSSDGGSSSSGRSSHLTN-----------SIEEASSPASEPEPPR--EP 286
E+ S+ S + S+H+T S+ S+PA P R P
Sbjct: 979 PSHHPHAREMRRSASEQSPNVSHSAHMTETRSKSFDYGSLSLTGPSAPAPVAPPARVAPP 1038
Query: 287 PRRPAFLPVGPDDTNSEYESGSESEPDLSEDADSPW----------LLSNLVSRMISEGS 336
RR FL V + ES E P ++++ P LS + S S G
Sbjct: 1039 ERRKCFL-VRQASLSRPPESELEVAPKGRQESEEPQPSSSKPSAKSSLSQISSAATSHGG 1097
Query: 337 SP-IRCPGQCLSPAPRPPGEPVSPAGGAAQDSQDPEA 372
P + PGQ RPP P P A Q P A
Sbjct: 1098 PPGGKGPGQ-----DRPPLGPTVPYTEALQVFHHPVA 1129
>gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sapiens]
Length = 2524
Score = 53.9 bits (128), Expect = 6e-07
Identities = 91/382 (23%), Positives = 129/382 (33%), Gaps = 51/382 (13%)
Query: 60 NEEEDDEDEEEEEEEEEGDGEGQEGGDP----GSEAPAPGPLIPSPSVEEPHKHRPTTLR 115
N D E E D GQ G P G++ P PGP P P + P PT
Sbjct: 743 NNSSDTESIPSPHTEAAKD-TGQNGPKPPATLGADGPPPGPPTPPPE-DIPAPTEPTPAS 800
Query: 116 LTTLGAQDSLNNNGGFDLVRPA-----SWQETALCSPAPEALRELPGPLPATDTGPGGAQ 170
T GA P +ETA P E + P G A+
Sbjct: 801 EAT-GAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPAAEELAVDTGKAE 859
Query: 171 SPVRPGCDCEGNRPAEPPAPGGTSPSSDPGIEADLRSRSSGGRGGRRSSQELSSPGSDS- 229
PV+ C E E PA G + +++ E L++ G GR ++ + S DS
Sbjct: 860 EPVKSECTEEAE---EGPAKGKDAEAAEATAEGALKAEKKEGGSGRATTAKSSGAPQDSD 916
Query: 230 ----------EDAGGARLGRMISSISETELELSSDGGSSSSGRSSHLTNSIEEASS---- 275
++A G R++S ++S + L + A++
Sbjct: 917 SSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKPLDLKQLKQRAAAIPPI 976
Query: 276 PASEPEPPRE--PPRRPAFLPVGPDDTNSEYESGSESEPDLS-------------EDADS 320
EPPRE P +PA P P N + ES + +P S ++A+
Sbjct: 977 VTKVHEPPREDAAPTKPA-PPAPPPPQNLQPESDAPQQPGSSPRGKSRSPAPPADKEAEK 1035
Query: 321 PWLLSNLVSRMIS-EGSSPIRCPGQCLSPAPRPPGEPVSPAGGAAQDSQDPEAAAG-PGG 378
P + G P G P P PP E + + A S A G P
Sbjct: 1036 PVFFPAFAAEAQKLPGDPPCWTSG---LPFPVPPREVIKASPHAPDPSAFSYAPPGHPLP 1092
Query: 379 VELVDMETLCAPPPPAPAAPRP 400
+ L D P PP + P P
Sbjct: 1093 LGLHDTARPVLPRPPTISNPPP 1114
Score = 37.4 bits (85), Expect = 0.055
Identities = 64/283 (22%), Positives = 97/283 (34%), Gaps = 43/283 (15%)
Query: 265 HLTNSIEEASSPASEPEPPREPPRRPAFLPVGPDDTNSEYESGSESEPDLSEDADSPWLL 324
H +E ++ + + P AF PV +D E S +E ++ E+A++
Sbjct: 669 HKLKMEKERNARRKKKKAPAAASEEAAFPPV-VEDEEMEASGVSGNEEEMVEEAEALHAS 727
Query: 325 SNLVSRMISEGSSPIRCPGQCLSPAPRPPGEPVSPAGGAAQDSQDPEAAAG----PGGVE 380
N V R G + + S P P E G Q+ P A G P G
Sbjct: 728 GNEVPRGECSGPATVNNSSDTES-IPSPHTEAAKDTG---QNGPKPPATLGADGPPPGPP 783
Query: 381 LVDMETLCAP--------------PPPAPAAPRPGPAQPGPCLFLSNPTRDTITPLWAAP 426
E + AP PPPAP P P+ P P + +T
Sbjct: 784 TPPPEDIPAPTEPTPASEATGAPTPPPAP----PSPSAPPPVVPKEEKEEETAAAPPVEE 839
Query: 427 GRAARPGRACSAACSEEEDEEDDEEE--EDAEDSAGSPGGRGTGPSAPRDASLVYDAVKY 484
G +P A A + EE + E E+AE+ GP+ +DA +
Sbjct: 840 GEEQKPPAAEELAVDTGKAEEPVKSECTEEAEE----------GPAKGKDAEAAEATAEG 889
Query: 485 TLVVD-EHTQLELVSLRRCAGLGHDSEED---SGGEASEEEAG 523
L + + + + +G DS+ S E E E G
Sbjct: 890 ALKAEKKEGGSGRATTAKSSGAPQDSDSSATCSADEVDEAEGG 932
Score = 31.2 bits (69), Expect = 4.0
Identities = 65/274 (23%), Positives = 89/274 (32%), Gaps = 62/274 (22%)
Query: 59 DNEEEDDEDEEEEEE------------------EEEGDGEGQEGGDPGSEA-PAP----- 94
D + E D D E E+ E+ G GG GS + PA
Sbjct: 1806 DRDRERDRDREREKSILTSTTTVEHAPIWRPGTEQSSGSSGSSGGGGGSSSRPASHSHAH 1865
Query: 95 --GPLIPSPSVEEPHKHRPTTLRLTTL---------GAQDSLNNNGGFDLVRPASWQETA 143
P+ SP ++ + RP+ L T + L + VRPA+ A
Sbjct: 1866 QHSPI--SPRTQDALQQRPSVLHNTGMKGIITAVEPSTPTVLRSTSTSSPVRPAATFPPA 1923
Query: 144 LCSPAPEALR----ELPGPLPATDTGPGGAQSPVRPGCDCEGNRPAEPPAPGGTSPSSDP 199
P L L P+ P A+ P RP D A+PPA G P+S P
Sbjct: 1924 THCPLGGTLDGVYPTLMEPVLLPKEAPRVAR-PERPRADTGHAFLAKPPARSGLEPASSP 1982
Query: 200 --GIE-----------ADLRSRSSGGRGGRRSSQELSSPGSDSEDAGGARLGRMISSISE 246
G E A + + +S + +P + + D + SI E
Sbjct: 1983 SKGSEPRPLVPPVSGHATIARTPAKNLAPHHASPDPPAPPASASDPHREKTQSKPFSIQE 2042
Query: 247 TELELSSDGGSSSSGRSSHLTNSIEEASSPASEP 280
EL GSS S E SP S P
Sbjct: 2043 LELRSLGYHGSSYSPEG-------VEPVSPVSSP 2069
Score = 30.4 bits (67), Expect = 6.8
Identities = 33/135 (24%), Positives = 45/135 (33%), Gaps = 35/135 (25%)
Query: 373 AAGPGGV-ELVDMETLCAPPPPAPAAPRPG-------PAQPGPCLFLSNPTRDTITPLWA 424
AAGP G+ +L + L PP P P P P P F S + ++P
Sbjct: 1732 AAGPRGIIDLSQVPHLPVLVPPTPGTPATAMDRLAYLPTAPQP--FSSRHSSSPLSP--G 1787
Query: 425 APGRAARPGRACSAACSEEEDEEDDEEEE-----------------------DAEDSAGS 461
P +P S+ + D E D + E + S+GS
Sbjct: 1788 GPTHLTKPTTTSSSERERDRDRERDRDREREKSILTSTTTVEHAPIWRPGTEQSSGSSGS 1847
Query: 462 PGGRGTGPSAPRDAS 476
GG G S P S
Sbjct: 1848 SGGGGGSSSRPASHS 1862
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 53.5 bits (127), Expect = 7e-07
Identities = 88/352 (25%), Positives = 118/352 (33%), Gaps = 28/352 (7%)
Query: 88 GSEAPAPGPLIPSPSVEEPHKHRPTTLRLTTLGAQDSLNNNGGFDLVRPASWQETALCSP 147
G AP P P V P + TT R LG Q L + + R + + +
Sbjct: 100 GERAPPAKNTSPGP-VSSPGRASGTT-RPGPLG-QKGLRISAEETVARGKATEAPKRSAL 156
Query: 148 APEALRELPGPLPATDTGPGGAQSPVRPGCDCEGNRPAEPPAPGGTSPSSDPGIEADLRS 207
+ A R+ GP P T + P A+ G + RPA P P+ P
Sbjct: 157 SAGARRDTSGPTPGTPS-PAMARRSRAAGTEVGLPRPAPSARP--RPPTEGP-------- 205
Query: 208 RSSGGRGGRRSSQELSSPGSDSEDAGGARLGRMISSISETELELSSDGGSSSSGRSSHLT 267
R S S+ E S AGG S+S + LSS S S R +
Sbjct: 206 RKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRA 265
Query: 268 NSIEEASSPASEP--EPPR-EPPRRPAFLPVGPDDTNSEYESG------SESEPDLSEDA 318
+ P PP+ PPR+ A +GP ++ S++ P L
Sbjct: 266 PAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATP 325
Query: 319 DSPWLLSNLVSRMISEGSSPIRCPGQCLSPAPRPPGEPVSPAGGAAQDSQDPEAAAGPGG 378
S L L + + SP P P+P P +P A P A
Sbjct: 326 HSSSLTCQLATPLPLAPPSPSAPPSLQTLPSP-----PATPPSQATTSLGSPTLQATHSF 380
Query: 379 VELVDMETLCAPPPPAPAAPRPGPAQPGPCLFLSNPTRDTITPLWAAPGRAA 430
+ + L PPP AP A P Q P S P TP AP A
Sbjct: 381 LPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALA 432
Score = 43.1 bits (100), Expect = 0.001
Identities = 100/378 (26%), Positives = 137/378 (36%), Gaps = 45/378 (11%)
Query: 84 GGDPGSEAPAPGPLIPSPSVEEPHKHRPTTLRLTTLGAQDSLNN--NGGFDLVRPASWQ- 140
G + G PAP P P E P K + +T + + G L RPAS
Sbjct: 184 GTEVGLPRPAPSAR-PRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSL 242
Query: 141 ---ETALCSPA---PEALRELPGPLPATDTGPGGAQSPVRPGCDCEGNRPAEPP-APGGT 193
T L SPA P A P + P G Q+ +RP + A P P +
Sbjct: 243 SSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQA-LRPPQVTPPRKDAAPALGPLSS 301
Query: 194 SPSSDPGIEADLRSRSSGGRGGRRSSQELSSPGSDSEDAGGARLGRMISSISETELELSS 253
SP + P A L+S++ S L+ + A L S + L S
Sbjct: 302 SPLATPSPSAALQSQAPPTLPATPHSSSLTC-----QLATPLPLAPPSPSAPPSLQTLPS 356
Query: 254 DGGSSSSGRSSHLTNSIEEASSPASEPEPPREP-----PRRPAFLPVGPDDTNSEYESGS 308
+ S ++ L + +A+ + P PP P P+ P L + P +
Sbjct: 357 PPATPPSQATTSLGSPTLQATH-SFLPSPPLSPLATPPPQAPPALALPP----LQAPPSP 411
Query: 309 ESEPDLSEDAD-SPWLLSNLVSRMISEGSSPIRCPGQCLSPAPRPPGEPVSPAGGAAQDS 367
+ P LS A SP + L ++ SP P +P P PVSP+ A S
Sbjct: 412 PASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP-PVQAPFSPPASPPVSPS--ATPPS 468
Query: 368 QDPEAAAGP------GGVELVDMETLCAPPPPAP---AAPRPGPAQPGPCLFLSNPTRDT 418
Q P + A P M PPP AP AAP A+P P P
Sbjct: 469 QAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPP----QAPPALA 524
Query: 419 ITPLWAAPG-RAARPGRA 435
PL A P A+ PG+A
Sbjct: 525 TPPLQALPSPPASFPGQA 542
Score = 40.4 bits (93), Expect = 0.007
Identities = 43/134 (32%), Positives = 56/134 (41%), Gaps = 22/134 (16%)
Query: 136 PASWQETALCSPAPE-ALRELPG-PLP-ATDTGPGGAQSPVRPGCDCEGNRPAEPPAPGG 192
PA+W PAP A R PG PLP TGPG A + + EG A P APG
Sbjct: 668 PAAWSR----GPAPPLAFRGAPGAPLPWPPATGPGSADG-LCTIYETEGPESATP-APGA 721
Query: 193 TSPSSDPGIEADLRSRSSGGRGGRRSSQELSSPGSDSEDAGGARLGRMISSI-----SET 247
P PG +SGG+ + SS G LG + +S+ S T
Sbjct: 722 LDPGPSPG--------TSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRT 773
Query: 248 ELELSSDGGSSSSG 261
L +++G + SG
Sbjct: 774 LLLAAAEGAAGGSG 787
Score = 35.4 bits (80), Expect = 0.21
Identities = 92/392 (23%), Positives = 121/392 (30%), Gaps = 36/392 (9%)
Query: 89 SEAPAPGPLIPSPSVEEPHKHRPTTLRLTTLGAQDSLNNNGGFDLVRPASWQETALCSPA 148
S+AP P P S P L + A SL P S T+L SP
Sbjct: 315 SQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPS-PPATPPSQATTSLGSPT 373
Query: 149 PEALRE-LPGP--LPATDTGPGGAQSPVRPGCDCEGNRPAEPP-APGGT-SPSSDPGIEA 203
+A LP P P P + P + PA PP +P T SP + +
Sbjct: 374 LQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAV 433
Query: 204 DLRSRSSGGRGGRRSSQELSSPGSDSEDAGGARLGRMISSISETELELSSDGGSSSSGRS 263
L S P S + S++ L++ +S
Sbjct: 434 HLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSP 493
Query: 264 SHLTNSIEEASSPASEPEPPREPPRRPAFLPVGPDDTNSEYESGSESEPDLSEDADSPWL 323
S A+ P P P PP + A P + + P S +P+
Sbjct: 494 S--------ATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPF- 544
Query: 324 LSNLVSRMISEGSSPIRCPGQCLSPAPRPPGEPVSPAGGAAQDSQDPEAAAGPGGVELVD 383
S S SP+ P P P V P+ A+ Q P PG V
Sbjct: 545 -----SPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVS 599
Query: 384 METLC---APPPPAPAAPRPGPAQPGPCLFLSNPTRDTITPLWAAPGRAARPGRACSAAC 440
L AP PP P + P GP L + + T TP R G AA
Sbjct: 600 GPRLTLALAPGPPPPPSRSPSSTLSGPDL-AGHSSSATSTP---EELRGYDSGPEGGAAA 655
Query: 441 SEEEDEEDDEEEEDAEDSAGSPGGRGTGPSAP 472
S DAE +A P GP+ P
Sbjct: 656 S---------PPPDAELAACHPAAWSRGPAPP 678
Score = 33.5 bits (75), Expect = 0.80
Identities = 46/165 (27%), Positives = 56/165 (33%), Gaps = 38/165 (23%)
Query: 340 RCPGQCLSPAPRPPGEPVSP------------AGGAAQDSQDPEAAAGPGGVELVDMETL 387
R PG PRPPG P P A GA E A G GG + +
Sbjct: 20 RAPGLL---TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPR 76
Query: 388 CAPP--------PPAPAAPRPGPAQPGPCLFLSNPTRDTITPLWAAPGRAA---RPGRAC 436
P PA P G + P P ++T ++PGRA+ RPG
Sbjct: 77 AGPTRSAGTSSRNPASRPPASGRGERAP------PAKNTSPGPVSSPGRASGTTRPGPLG 130
Query: 437 SAA--CSEEEDEEDDEEEEDAEDSAGSPGGR----GTGPSAPRDA 475
S EE + E + SA S G R G P P A
Sbjct: 131 QKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPA 175
Score = 33.5 bits (75), Expect = 0.80
Identities = 37/137 (27%), Positives = 47/137 (34%), Gaps = 22/137 (16%)
Query: 277 ASEPEPPREPPRRPAFLPVGPDDTNSEYESGSESEPDLSEDADSPWLLSNLVSRMISEGS 336
A P PP P R P+ GPD + S + S P+ DS EG
Sbjct: 606 ALAPGPPPPPSRSPSSTLSGPDLAG--HSSSATSTPEELRGYDSG-----------PEGG 652
Query: 337 SPIRCPGQCLSPAPRP------PGEPVSPAGGAAQDSQDPEAAAGPGGVELVDMETLCAP 390
+ P A P P P++ G P A GPG + + T+
Sbjct: 653 AAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPAT-GPGSAD--GLCTIYET 709
Query: 391 PPPAPAAPRPGPAQPGP 407
P A P PG PGP
Sbjct: 710 EGPESATPAPGALDPGP 726
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 53.5 bits (127), Expect = 7e-07
Identities = 111/439 (25%), Positives = 149/439 (33%), Gaps = 89/439 (20%)
Query: 55 EMIDDNEEEDDEDEEEEEEEEEGDGEGQEGGDPGSEAPAPGPLIPSPSVEEPHKHRPTTL 114
E+ + +EE+ EE+E+ + +E G+PG P P + KHR
Sbjct: 902 EISEASEEKRPRPSTPAEEDEDDPEQEKEAGEPGRPGTKP-PKRDEERGKTQGKHR---- 956
Query: 115 RLTTLGAQDSLNNNGGFDLVRPASWQETALCSPAPEALRELPGPLPATDTGPGGAQSPVR 174
+ AL S EA +E D
Sbjct: 957 -------------------------KSFALDSEGEEASQESSSEKDEEDDEEDEEDEDRE 991
Query: 175 PGCDCEGNRPAEPPAPGGTSPSSDPGIEADLRSRSSGGRGGRRSSQELSSPGSDSEDAGG 234
D E G SD + L + S G S+ SS S S +
Sbjct: 992 EAVD---TTKKETEVSDGEDEESDSSSKCSLYADSDGENDSTSDSESSSSSSSSSSSS-- 1046
Query: 235 ARLGRMISSISETELELSSDGGSSSSGRSSHLTNSIEEASSPASEPE---PPRE---PPR 288
SS SSSS S + EE PA+ P PPRE P
Sbjct: 1047 -----------------SSSSSSSSSSSSESSSEDEEEEERPAALPSASPPPREVPVPTP 1089
Query: 289 RPAFLPVGPDDTNSEYESGSESEPDLSEDADSPWLLSNLVSRMISEGSSPIRCPGQCL-- 346
P +PV E +GS P L E SP + S S+P+R P
Sbjct: 1090 APVEVPV------PERVAGSPVTP-LPEQEASPARPAGPTEE--SPPSAPLRPPEPPAGP 1140
Query: 347 -SPAPRPPGEPVSPAGGAAQDSQDPEAAAGPGGVELVDMETLCAP-PPPA--PAAPRPGP 402
+PAPRP P SP P V +E + AP PPPA P A PGP
Sbjct: 1141 PAPAPRPDERPSSPI------PLLPPPKKRRKTVSFSAIEVVPAPEPPPATPPQAKFPGP 1194
Query: 403 AQ----PGPCLFLSNPTRDTITPLWAAPGRAARPGRACSAA---CSEEEDEEDDEEEEDA 455
A G + N D + + + P +R GR+ + +EEE+ E E + A
Sbjct: 1195 ASRKAPRGVERTIRNLPLDHASLVKSWPEEVSRGGRSRAGGRGRLTEEEEAEPGTEVDLA 1254
Query: 456 --EDSAGSPGGRGTGPSAP 472
D A +P RG P+ P
Sbjct: 1255 VLADLALTPARRGL-PALP 1272
Score = 50.1 bits (118), Expect = 8e-06
Identities = 117/478 (24%), Positives = 171/478 (35%), Gaps = 119/478 (24%)
Query: 48 QDDFQEFEMIDDNEEEDDEDEEE-----EEEEEEGDGEGQEGGDPGSE----APAPGPLI 98
Q+ E + DD E+E+DED EE ++E E DGE +E D S+ A + G
Sbjct: 970 QESSSEKDEEDDEEDEEDEDREEAVDTTKKETEVSDGEDEE-SDSSSKCSLYADSDGEND 1028
Query: 99 PSPSVEEPHKHRPTTLRLTTLGAQDSLNNNGGFDLVRPASWQETALCSPAPEALRELPGP 158
+ E ++ ++ + S +++ + AL S +P RE+P P
Sbjct: 1029 STSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAALPSASPPP-REVPVP 1087
Query: 159 LPA--------------TDTGPGGAQSPVRPGCDCEGN------RPAEPPA-PGGTSPSS 197
PA P SP RP E + RP EPPA P +P
Sbjct: 1088 TPAPVEVPVPERVAGSPVTPLPEQEASPARPAGPTEESPPSAPLRPPEPPAGPPAPAPRP 1147
Query: 198 D-------PGIEADLRSRSSGGRG------------GRRSSQELSSPGSDSEDAGGARLG 238
D P + + R + + P S G R
Sbjct: 1148 DERPSSPIPLLPPPKKRRKTVSFSAIEVVPAPEPPPATPPQAKFPGPASRKAPRGVERTI 1207
Query: 239 RMI----SSISETELELSSDGGSSSSGRSSHLTNSIEEASSPASE------PEPPREPPR 288
R + +S+ ++ E S GG S +G LT EE + P +E + P R
Sbjct: 1208 RNLPLDHASLVKSWPEEVSRGGRSRAGGRGRLTE--EEEAEPGTEVDLAVLADLALTPAR 1265
Query: 289 RPAFLPVGPDDTNSEYESGSESEPDLSEDADSPWLLSNLVSRMISEGSSPIRCPGQCLSP 348
R LP P +SE + S++A+ P L+S ++ E + + +P
Sbjct: 1266 RG--LPALPAVEDSE-------ATETSDEAERP---RPLLSHILLEHNYALAVKPTPPAP 1313
Query: 349 APRPPGEPVSPAGGAAQDSQDPEAAAGPGGVELVDMETLCAPPPPAPAAPRPGPAQPGPC 408
A RPP EPV PA A S E P E+V E A P P Q
Sbjct: 1314 ALRPP-EPV-PAPAALFSSPADEVLEAP---EVVVAE-----------AEEPKPQQ---- 1353
Query: 409 LFLSNPTRDTITPLWAAPGRAARPGRACSAACSEEEDEEDDEEEEDAEDSAGSPGGRG 466
L + EE +EE +EEEE++ DS+ S G G
Sbjct: 1354 --LQQQREEG----------------------EEEGEEEGEEEEEESSDSSSSSDGEG 1387
Score = 43.5 bits (101), Expect = 8e-04
Identities = 77/348 (22%), Positives = 122/348 (35%), Gaps = 41/348 (11%)
Query: 158 PLPATDTGPGGAQSPVRPGCDCEGNRPAEPPAPGGTSPSSDPGIEADLRSRSSGGRGGRR 217
P T G G +P +R P + G +P S G R + +
Sbjct: 228 PAGTTAVGTPGNGTPCSQDTSFSSSRQDTPSSFGQFTPQSSQGTPYTSRGSTPYSQDSAY 287
Query: 218 SSQELSSP------GSDSEDAGGAR--LGRMISSISETELELSSDGGSSSSGRSSHLTNS 269
SS S+ + +DA R S+ + T + ++ +SSS SS L++S
Sbjct: 288 SSSTTSTSFKPRRSENSYQDAFSRRHFSASSASTTASTAIAATTAATASSSASSSSLSSS 347
Query: 270 IEEASSPASEPEPPREPPRRPAFLPVGPDDTNSEYESGSESEPDLSEDADSPW--LLSNL 327
+SS +S + PA+ ++ + Y+ + P + + P N
Sbjct: 348 -SSSSSSSSSSQFRSSDANYPAYY-----ESWNRYQRHTSYPPRRATREEPPGAPFAENT 401
Query: 328 VSRMISEGSS-----PIRCPGQCLSP--APRPPGEPVSPAGGAAQDSQDPEAAAGPGGVE 380
R +S P R Q P + PP EP P GG PE
Sbjct: 402 AERFPPSYTSYLPPEPSRPTDQDYRPPASEAPPPEPPEPGGGGGGGGPSPERE------- 454
Query: 381 LVDMETLCAPPPPAPA-APRPGPAQPGPCL-FLSNPTRDTITPLWAAPGRAARPGRACSA 438
E +P P +PA + P P + F + + D+ + R+ +
Sbjct: 455 ----EVRTSPRPASPARSGSPAPETTNESVPFAQHSSLDSRIEMLLKEQRS----KFSFL 506
Query: 439 ACSEEEDEEDDEEEEDAEDSAGS-PGGRGTGPSAPRDASLVYDAVKYT 485
A EE+EE+ A D+ P G G GP P A ++ V T
Sbjct: 507 ASDTEEEEENSSMVLGARDTGSEVPSGSGHGPCTPPPAPANFEDVAPT 554
Score = 43.5 bits (101), Expect = 8e-04
Identities = 89/424 (20%), Positives = 137/424 (32%), Gaps = 93/424 (21%)
Query: 31 DSLSLGRSEQPHPICSFQDDFQEFEMIDDNEEEDDEDEEEEEEEEEGDGEGQEGGDPGSE 90
DS S S S + E EDEEEEE P E
Sbjct: 1028 DSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEER----PAALPSASPPPRE 1083
Query: 91 APAPGPLIPSPSVEEPHKHRPTTLRLTTLGAQDSLNNNGGFDLVRPAS-WQETALCSP-- 147
P P P VE P R +T L Q++ RPA +E+ +P
Sbjct: 1084 VPVPTP----APVEVPVPERVAGSPVTPLPEQEA-------SPARPAGPTEESPPSAPLR 1132
Query: 148 APEALRELPGPLPATDTGPGG-----------------AQSPVRPGCDCEGNRPAEPPAP 190
PE P P P D P + V P + P + P
Sbjct: 1133 PPEPPAGPPAPAPRPDERPSSPIPLLPPPKKRRKTVSFSAIEVVPAPEPPPATPPQAKFP 1192
Query: 191 GGTSPSSDPGIEADLRS--------------------RSSGGRGGRRSSQELSSPGSDSE 230
G S + G+E +R+ RS G GR + +E + PG++ +
Sbjct: 1193 GPASRKAPRGVERTIRNLPLDHASLVKSWPEEVSRGGRSRAGGRGRLTEEEEAEPGTEVD 1252
Query: 231 DAGGARLG--------RMISSISETELELSSDGGSSSSGRSSHLTNSIEEASSPASEPEP 282
A A L + ++ ++E +SD SH+ +E + A +P P
Sbjct: 1253 LAVLADLALTPARRGLPALPAVEDSEATETSDEAERPRPLLSHIL--LEHNYALAVKPTP 1310
Query: 283 PREPPRRPAFLPVGPDDTNSEYESGSESEPDLSEDADSPWLLSNLVSRMISEGSSPIRCP 342
P R P +P +S + E+ + +A+ P P +
Sbjct: 1311 PAPALRPPEPVPAPAALFSSPADEVLEAPEVVVAEAEEP---------------KPQQLQ 1355
Query: 343 GQCLSPAPRPPGEPVSPAGGAAQDSQDPEAAAGPGGVELVDMETLCA-------PPPPAP 395
Q R GE G ++ + ++++ G + +L + PPPP P
Sbjct: 1356 QQ------REEGEEEGEEEGEEEEEESSDSSSSSDGEGALRRRSLRSHARRRRPPPPPPP 1409
Query: 396 AAPR 399
PR
Sbjct: 1410 PPPR 1413
Score = 42.7 bits (99), Expect = 0.001
Identities = 61/260 (23%), Positives = 84/260 (32%), Gaps = 43/260 (16%)
Query: 154 ELPGPLPATDTGPGGAQSPVRPGCDCEGN-RPAEP-----PAPGGTSPSSDPGIEADLRS 207
E P P P G GG P + + RPA P PAP T+ S + L S
Sbjct: 431 EAPPPEPPEPGGGGGGGGPSPEREEVRTSPRPASPARSGSPAPETTNESVPFAQHSSLDS 490
Query: 208 RSSGGRGGRRSSQELSSPGSDSEDAGGARLGRMISSISETELELSSDGGSSSSGRSSHLT 267
R +RS + ++ E+ + M+ +T E+ S G
Sbjct: 491 RIEMLLKEQRSKFSFLASDTEEEEENSS----MVLGARDTGSEVPSGSGHGPCTPPPAPA 546
Query: 268 NSIEEASSPASEPEPPREPPRRPAFLPVGPDDTNSEYESGSESEPDLSEDADSPWLLSNL 327
N + A + + EP RE P+ + N S + ++S+D
Sbjct: 547 NFEDVAPTGSGEPGATRESPKA--------NGQNQASPCSSGDDMEISDD---------- 588
Query: 328 VSRMISEGSSPIRCPGQCLSPAPRPPGEPVSPAGGAAQDSQDPEAAAGPGGVELVDMETL 387
G SP P P P PP P P P A+ P G L
Sbjct: 589 -----DRGGSPPPAPTPPQQPPPPPPPPPPPP----------PYLASLPLGYPPHQPAYL 633
Query: 388 CAPPPPAPAAPRPGPAQPGP 407
P P P P P P P
Sbjct: 634 LPPRPDGPPPPEYPPPPPPP 653
Score = 35.4 bits (80), Expect = 0.21
Identities = 46/178 (25%), Positives = 61/178 (34%), Gaps = 44/178 (24%)
Query: 433 GRACSAACSEEEDEEDDEEEEDAEDSAGSPGGRGTGPSAPRDASLVYDAVKYTLVVDEHT 492
G S S E+DEEDDEE+E+ ED V K T V D
Sbjct: 965 GEEASQESSSEKDEEDDEEDEEDEDR----------------EEAVDTTKKETEVSD--- 1005
Query: 493 QLELVSLRRCAGLGHDSEEDSGGEASEEEAGAALLGGGQVSGDTSPDSPDLTFSKKFLNV 552
G D E DS + S L D++ DS + S
Sbjct: 1006 -------------GEDEESDSSSKCS-------LYADSDGENDSTSDSESSSSSSS---- 1041
Query: 553 FVNSTSRSSSTESFGLFSCLVNGEEREQTHRAVFRFIPRHPDELELDVDDPVLVEAEE 610
+S+S SSS+ S S + +E E+ A P E+ + PV V E
Sbjct: 1042 -SSSSSSSSSSSSSSSSSESSSEDEEEEERPAALPSASPPPREVPVPTPAPVEVPVPE 1098
Score = 34.3 bits (77), Expect = 0.47
Identities = 25/94 (26%), Positives = 37/94 (39%)
Query: 18 PSGPALLSPSVLQDSLSLGRSEQPHPICSFQDDFQEFEMIDDNEEEDDEDEEEEEEEEEG 77
P PAL P + +L S + + + E E + + +E EEE EEEG
Sbjct: 1310 PPAPALRPPEPVPAPAALFSSPADEVLEAPEVVVAEAEEPKPQQLQQQREEGEEEGEEEG 1369
Query: 78 DGEGQEGGDPGSEAPAPGPLIPSPSVEEPHKHRP 111
+ E +E D S + G L + RP
Sbjct: 1370 EEEEEESSDSSSSSDGEGALRRRSLRSHARRRRP 1403
Score = 33.9 bits (76), Expect = 0.61
Identities = 53/228 (23%), Positives = 76/228 (33%), Gaps = 47/228 (20%)
Query: 82 QEGGDPGSEAPAPGPLIP---------SPSVEEPHKH-RPTTLRLTTLGAQDSLNNNGGF 131
Q+ P SEAP P P P SP EE RP + + A ++ N + F
Sbjct: 423 QDYRPPASEAPPPEPPEPGGGGGGGGPSPEREEVRTSPRPASPARSGSPAPETTNESVPF 482
Query: 132 DLVRPASWQETALCSPAPEALRELPGPLP--ATDTGPGGAQSPVRPGCDCEGNRPAEPPA 189
Q ++L S L+E A+DT S + G G+
Sbjct: 483 A-------QHSSLDSRIEMLLKEQRSKFSFLASDTEEEEENSSMVLGARDTGSEVPSGSG 535
Query: 190 PGGTSPSSDPGIEADLRSRSSGGRGGRRSSQELSSPGSDSEDAGGARLGRMISSISETEL 249
G +P P D+ SG G R S + + S + G ++
Sbjct: 536 HGPCTPPPAPANFEDVAPTGSGEPGATRESPKANGQNQASPCSSG------------DDM 583
Query: 250 ELSSDGGSSSSGRSSHLTNSIEEASSPASEPEPPREPPRRPAFLPVGP 297
E+S D + SP P PP++PP P P P
Sbjct: 584 EISDD----------------DRGGSPPPAPTPPQQPPPPPPPPPPPP 615
Score = 32.0 bits (71), Expect = 2.3
Identities = 43/180 (23%), Positives = 65/180 (36%), Gaps = 20/180 (11%)
Query: 443 EEDEEDDEEEEDAEDSAGSPGGRGTGPSAPRDASLVYDAVKYTLVVDEHTQLELVSLRRC 502
EEDE+D E+E++A G PG GT P RD K+ ++ E S
Sbjct: 919 EEDEDDPEQEKEA----GEPGRPGTKP-PKRDEERGKTQGKHRKSFALDSEGEEASQESS 973
Query: 503 AGLGHDSEEDSGGEASEEEAGAALLGGGQVSGDTSPDSP---------------DLTFSK 547
+ + +E+ + EEA +VS +S D T
Sbjct: 974 SEKDEEDDEEDEEDEDREEAVDTTKKETEVSDGEDEESDSSSKCSLYADSDGENDSTSDS 1033
Query: 548 KFLNVFVNSTSRSSSTESFGLFSCLVNGEEREQTHRAVFRFIPRHPDELELDVDDPVLVE 607
+ + +S+S SSS+ S S + E E+ P E+ V P VE
Sbjct: 1034 ESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAALPSASPPPREVPVPTPAPVE 1093
>gi|161169015 neuron navigator 2 isoform 3 [Homo sapiens]
Length = 2365
Score = 53.5 bits (127), Expect = 7e-07
Identities = 80/352 (22%), Positives = 130/352 (36%), Gaps = 81/352 (23%)
Query: 140 QETALCSPAPEALRELPGPLPATDTGPGGAQSPVRPGCDCEGNRPAEPPAPGGTSPSSDP 199
Q+ L SP P A+ ++ G G Q PV P C+ ++PA P
Sbjct: 134 QKQHLSSPLPPAVSQVAGAPSQCQAGTPQQQVPVTPQAPCQPHQPA---------PHQQS 184
Query: 200 GIEADLRSRSSGGRGGRRSSQELSSPGSDSEDAGGARLGRMISSISETELELSSDGGSSS 259
+A+++SR G + +S+ GS+++ GG+ +++
Sbjct: 185 KAQAEMQSRLPG------PTARVSAAGSEAKTRGGS---------------------TTA 217
Query: 260 SGRSSHLTNSIEEASSPASEPEPPREPPRRP-----AFLPVGPDDTNSEYESGSESEPDL 314
+ R S N+ +++ S P PP + P + P D+ + ESGS S P
Sbjct: 218 NNRRSQSFNNYDKSKPVTSPPPPPSSHEKEPLASSASSHPGMSDNAPASLESGSSSTPTN 277
Query: 315 SED---------ADSPWLLSNL-VSRMISEGSSPIRCPGQCLSPAPRPPGEPVSPAGGAA 364
A PW +L V + ++ PG APRP E + PA
Sbjct: 278 CSTSSAIPQPGAATKPWRSKSLSVKHSATVSMLSVKPPG---PEAPRPTPEAMKPAPNNQ 334
Query: 365 QDSQD----------PEAAAGPGG--VELVDMETLCA--PPPPAPAAPR----PGPAQPG 406
+ + +A GPG +ETL + AA R GPA
Sbjct: 335 KSMLEKLKLFNSKGGSKAGEGPGSRDTSCERLETLPSFEESEELEAASRMLTTVGPASSS 394
Query: 407 PCLFLSNPTRDTITPLWAAPGRAARPGRACSAACSEEEDEEDDEEEEDAEDS 458
P + L + T + RA + S+ E+++E + E+D E S
Sbjct: 395 PKIALKGIAQRTFS-------RALTNKK--SSLKGNEKEKEKQQREKDKEKS 437
>gi|161169013 neuron navigator 2 isoform 1 [Homo sapiens]
Length = 2432
Score = 53.5 bits (127), Expect = 7e-07
Identities = 80/352 (22%), Positives = 130/352 (36%), Gaps = 81/352 (23%)
Query: 140 QETALCSPAPEALRELPGPLPATDTGPGGAQSPVRPGCDCEGNRPAEPPAPGGTSPSSDP 199
Q+ L SP P A+ ++ G G Q PV P C+ ++PA P
Sbjct: 198 QKQHLSSPLPPAVSQVAGAPSQCQAGTPQQQVPVTPQAPCQPHQPA---------PHQQS 248
Query: 200 GIEADLRSRSSGGRGGRRSSQELSSPGSDSEDAGGARLGRMISSISETELELSSDGGSSS 259
+A+++SR G + +S+ GS+++ GG+ +++
Sbjct: 249 KAQAEMQSRLPG------PTARVSAAGSEAKTRGGS---------------------TTA 281
Query: 260 SGRSSHLTNSIEEASSPASEPEPPREPPRRP-----AFLPVGPDDTNSEYESGSESEPDL 314
+ R S N+ +++ S P PP + P + P D+ + ESGS S P
Sbjct: 282 NNRRSQSFNNYDKSKPVTSPPPPPSSHEKEPLASSASSHPGMSDNAPASLESGSSSTPTN 341
Query: 315 SED---------ADSPWLLSNL-VSRMISEGSSPIRCPGQCLSPAPRPPGEPVSPAGGAA 364
A PW +L V + ++ PG APRP E + PA
Sbjct: 342 CSTSSAIPQPGAATKPWRSKSLSVKHSATVSMLSVKPPG---PEAPRPTPEAMKPAPNNQ 398
Query: 365 QDSQD----------PEAAAGPGG--VELVDMETLCA--PPPPAPAAPR----PGPAQPG 406
+ + +A GPG +ETL + AA R GPA
Sbjct: 399 KSMLEKLKLFNSKGGSKAGEGPGSRDTSCERLETLPSFEESEELEAASRMLTTVGPASSS 458
Query: 407 PCLFLSNPTRDTITPLWAAPGRAARPGRACSAACSEEEDEEDDEEEEDAEDS 458
P + L + T + RA + S+ E+++E + E+D E S
Sbjct: 459 PKIALKGIAQRTFS-------RALTNKK--SSLKGNEKEKEKQQREKDKEKS 501
>gi|38044282 neuron navigator 2 isoform 2 [Homo sapiens]
Length = 2429
Score = 53.5 bits (127), Expect = 7e-07
Identities = 80/352 (22%), Positives = 130/352 (36%), Gaps = 81/352 (23%)
Query: 140 QETALCSPAPEALRELPGPLPATDTGPGGAQSPVRPGCDCEGNRPAEPPAPGGTSPSSDP 199
Q+ L SP P A+ ++ G G Q PV P C+ ++PA P
Sbjct: 198 QKQHLSSPLPPAVSQVAGAPSQCQAGTPQQQVPVTPQAPCQPHQPA---------PHQQS 248
Query: 200 GIEADLRSRSSGGRGGRRSSQELSSPGSDSEDAGGARLGRMISSISETELELSSDGGSSS 259
+A+++SR G + +S+ GS+++ GG+ +++
Sbjct: 249 KAQAEMQSRLPG------PTARVSAAGSEAKTRGGS---------------------TTA 281
Query: 260 SGRSSHLTNSIEEASSPASEPEPPREPPRRP-----AFLPVGPDDTNSEYESGSESEPDL 314
+ R S N+ +++ S P PP + P + P D+ + ESGS S P
Sbjct: 282 NNRRSQSFNNYDKSKPVTSPPPPPSSHEKEPLASSASSHPGMSDNAPASLESGSSSTPTN 341
Query: 315 SED---------ADSPWLLSNL-VSRMISEGSSPIRCPGQCLSPAPRPPGEPVSPAGGAA 364
A PW +L V + ++ PG APRP E + PA
Sbjct: 342 CSTSSAIPQPGAATKPWRSKSLSVKHSATVSMLSVKPPG---PEAPRPTPEAMKPAPNNQ 398
Query: 365 QDSQD----------PEAAAGPGG--VELVDMETLCA--PPPPAPAAPR----PGPAQPG 406
+ + +A GPG +ETL + AA R GPA
Sbjct: 399 KSMLEKLKLFNSKGGSKAGEGPGSRDTSCERLETLPSFEESEELEAASRMLTTVGPASSS 458
Query: 407 PCLFLSNPTRDTITPLWAAPGRAARPGRACSAACSEEEDEEDDEEEEDAEDS 458
P + L + T + RA + S+ E+++E + E+D E S
Sbjct: 459 PKIALKGIAQRTFS-------RALTNKK--SSLKGNEKEKEKQQREKDKEKS 501
>gi|116089331 human immunodeficiency virus type I enhancer binding
protein 3 [Homo sapiens]
Length = 2406
Score = 53.5 bits (127), Expect = 7e-07
Identities = 47/154 (30%), Positives = 67/154 (43%), Gaps = 31/154 (20%)
Query: 53 EFEMIDDNEEEDDEDEEEEEEEEEGDGEGQEGGDPGSEAPAPGPLIPSPSVEEPHKHRPT 112
+F ++D++ + D DE+E+E+EEE E P SEAP PGP PH R
Sbjct: 1846 QFSDLEDSDSDSDLDEDEDEDEEESQDELSR---PSSEAPPPGP---------PHALRAD 1893
Query: 113 TLRLTTLGAQDSLNNNGGFDLVRPASWQE-----TALCSPAPEALRELP--GPLP----A 161
+ + LG Q G + R +S E + CS + +++ LP GP P
Sbjct: 1894 SSPI--LGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVE 1951
Query: 162 TDTGPGGAQSPVRPGCDCEGNRPAEPPAPGGTSP 195
DTG + PV P RP P G+ P
Sbjct: 1952 KDTGSALSYKPVSP------RRPWSPSKEAGSRP 1979
Score = 41.6 bits (96), Expect = 0.003
Identities = 82/337 (24%), Positives = 114/337 (33%), Gaps = 49/337 (14%)
Query: 71 EEEEEEGDGEGQEGGD-PGSEAPAPGPLIPSPSVEEPHKHRPTTLRLTTLGAQDSLNNNG 129
E+ + G EG D P ++ P+P P +P H +P +R + + L
Sbjct: 807 EKSDSLEQPSGLEGEDKPLAQFPSPPP---APHGRSAHSLQPKLVRQPNIQVPEILVTE- 862
Query: 130 GFDLVRPASWQETALCSPAPEALRELPGP--------LPATDTGPGGAQSPVRPGCDCEG 181
+ RP + E PE E P LPA P + + G
Sbjct: 863 --EPDRPDTEPEPP--PKEPEKTEEFQWPQRSQTLAQLPAEKLPPKKKRLRLAEMAQSSG 918
Query: 182 NRPAEPPAPGGTSPSSDPGIEADLRSRSSGGRGGRRSSQELSSPGSD--SEDAGGARLGR 239
E P SPS + + SRS+ E SP SD + G L
Sbjct: 919 ESSFESSVPLSRSPSQESNVSLSGSSRSASFERDDHGKAEAPSPSSDMRPKPLGTHMLTV 978
Query: 240 MISSISETELELSSDGGSSSSGRSSHLTN-----------SIEEASSPASEPEPPR--EP 286
E+ S+ S + S+H+T S+ S+PA P R P
Sbjct: 979 PSHHPHAREMRRSASEQSPNVSHSAHMTETRSKSFDYGSLSLTGPSAPAPVAPPARVAPP 1038
Query: 287 PRRPAFLPVGPDDTNSEYESGSESEPDLSEDADSPW----------LLSNLVSRMISEGS 336
RR FL V + ES E P ++++ P LS + S S G
Sbjct: 1039 ERRKCFL-VRQASLSRPPESELEVAPKGRQESEEPQPSSSKPSAKSSLSQISSAATSHGG 1097
Query: 337 SP-IRCPGQCLSPAPRPPGEPVSPAGGAAQDSQDPEA 372
P + PGQ RPP P P A Q P A
Sbjct: 1098 PPGGKGPGQ-----DRPPLGPTVPYTEALQVFHHPVA 1129
>gi|226437579 NAC alpha domain containing [Homo sapiens]
Length = 1562
Score = 53.1 bits (126), Expect = 1e-06
Identities = 114/473 (24%), Positives = 170/473 (35%), Gaps = 79/473 (16%)
Query: 14 GLLLPSGPALLSPSVLQDSLSLGRSEQPHPICSFQDDFQEFEMIDDNEEEDDEDEEEEEE 73
GL LP A+ P LQD+ S P P+ + Q+ E +D
Sbjct: 873 GLTLPQDSAMTPPLPLQDT---DLSSAPKPVAAATPVSQQAEE-GLTLPQDSAMTAPLPL 928
Query: 74 EEEGDGEGQEGGDPGSEAPAPGPLIPSPSVEEPHKHRPTTLRLTTLGAQDSLNNNGGFDL 133
++ G G P P + +++ P T + T+ Q+ G
Sbjct: 929 QDTGPTSG----------PEPLAVATPQTLQAEAGCAPGTEPVATMAQQEVGEALGP--- 975
Query: 134 VRPASWQETALCS--PAPEALRELP--GPLPATDTG-PGGAQSPVRPGCDCEGNRPAEPP 188
RPA ++ A P P AL ++ P PA + G P AQ E EP
Sbjct: 976 -RPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSLPEPA 1034
Query: 189 APGGTSPS---SDPGIEADLRSRSSGGRGGRRSSQELSSPGSDSEDAGGARLGRMISSIS 245
+ G + S PG EA L +R+ G G + S + + +++ GG + ++
Sbjct: 1035 SGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEGG------LKPLA 1088
Query: 246 ETELELSSDGGSSSSGRSSHLTNSIEEASSPASEPEPPREPPRRPAFLPVGPDDTNSEYE 305
+ S+ GG+ E P PP P+ + +
Sbjct: 1089 QEHGPRSALGGAR----------------------EVPDAPPA------ACPEVSQARLL 1120
Query: 306 SGSESEPDLSEDADSPWLLSNLVSRMISEGSSPIRCPGQCLSPAPRPPGEPVSPAGGAAQ 365
S + E LS + L + V+ S S P G +S R G P +PA +A
Sbjct: 1121 SPAREERGLSGKSTPEPTLPSAVATEASLDSCPESSVG-AVSSLDR--GCPDAPAPTSAP 1177
Query: 366 DSQDPEAAAGPGGVELVDMETLCAPPPPAPAAPRPGPAQPGPCLFLSNPTRDTITPLW-- 423
SQ PE G G VE P P+ QP L P+ PL
Sbjct: 1178 TSQQPEPVLGLGSVE---------QPHEVPSVLGTPLLQPPENLAKGQPSTPVDRPLGPD 1228
Query: 424 -AAPGR---AARPGRACSAACSEEEDEEDDEEEEDAEDSAGSPGGR-GTGPSA 471
+APG AA P A C ++ +ED E+E+ S G P + G P+A
Sbjct: 1229 PSAPGTLAGAALPPLEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQPAA 1281
Score = 32.0 bits (71), Expect = 2.3
Identities = 29/104 (27%), Positives = 42/104 (40%), Gaps = 8/104 (7%)
Query: 268 NSIEEASSPASEPEPPREPPRRPAFLPVGPDDTNSEYESGSESEPDLSEDADSPWLLSNL 327
+S+E+ P S PP + +PA V T +G P +S SP L +
Sbjct: 1257 DSVEDEEPPGSLGLPPPQAGVQPAAAAVS--GTTQPLGTG----PRVSLSPHSPLLSPKV 1310
Query: 328 VSRMISEGSSPIRCPGQCLSPAPRPPGEPVSPAGGAAQDSQDPE 371
S + + I P C P P P P P G +A + Q+ E
Sbjct: 1311 ASMDAKDLALQILPP--CQVPPPSGPQSPAGPQGLSAPEQQEDE 1352
Score = 30.0 bits (66), Expect = 8.8
Identities = 28/105 (26%), Positives = 42/105 (40%), Gaps = 10/105 (9%)
Query: 311 EPDLSEDADSPWLLSNLVSRMISEG---------SSPIRCPGQCLSPAPRPPGEPVSPAG 361
+ DLS A P + +VS+ EG + P+ LS AP+P +
Sbjct: 810 DTDLSS-APKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQ 868
Query: 362 GAAQDSQDPEAAAGPGGVELVDMETLCAPPPPAPAAPRPGPAQPG 406
A + P+ +A + L D + AP P A A P A+ G
Sbjct: 869 QAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEG 913
>gi|239754540 PREDICTED: NAC alpha domain containing [Homo sapiens]
Length = 1522
Score = 53.1 bits (126), Expect = 1e-06
Identities = 114/473 (24%), Positives = 170/473 (35%), Gaps = 79/473 (16%)
Query: 14 GLLLPSGPALLSPSVLQDSLSLGRSEQPHPICSFQDDFQEFEMIDDNEEEDDEDEEEEEE 73
GL LP A+ P LQD+ S P P+ + Q+ E +D
Sbjct: 833 GLTLPQDSAMTPPLPLQDT---DLSSAPKPVAAATPVSQQAEE-GLTLPQDSAMTAPLPL 888
Query: 74 EEEGDGEGQEGGDPGSEAPAPGPLIPSPSVEEPHKHRPTTLRLTTLGAQDSLNNNGGFDL 133
++ G G P P + +++ P T + T+ Q+ G
Sbjct: 889 QDTGPTSG----------PEPLAVATPQTLQAEAGCAPGTEPVATMAQQEVGEALGP--- 935
Query: 134 VRPASWQETALCS--PAPEALRELP--GPLPATDTG-PGGAQSPVRPGCDCEGNRPAEPP 188
RPA ++ A P P AL ++ P PA + G P AQ E EP
Sbjct: 936 -RPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSLPEPA 994
Query: 189 APGGTSPS---SDPGIEADLRSRSSGGRGGRRSSQELSSPGSDSEDAGGARLGRMISSIS 245
+ G + S PG EA L +R+ G G + S + + +++ GG + ++
Sbjct: 995 SGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEGG------LKPLA 1048
Query: 246 ETELELSSDGGSSSSGRSSHLTNSIEEASSPASEPEPPREPPRRPAFLPVGPDDTNSEYE 305
+ S+ GG+ E P PP P+ + +
Sbjct: 1049 QEHGPRSALGGAR----------------------EVPDAPPA------ACPEVSQARLL 1080
Query: 306 SGSESEPDLSEDADSPWLLSNLVSRMISEGSSPIRCPGQCLSPAPRPPGEPVSPAGGAAQ 365
S + E LS + L + V+ S S P G +S R G P +PA +A
Sbjct: 1081 SPAREERGLSGKSTPEPTLPSAVATEASLDSCPESSVG-AVSSLDR--GCPDAPAPTSAP 1137
Query: 366 DSQDPEAAAGPGGVELVDMETLCAPPPPAPAAPRPGPAQPGPCLFLSNPTRDTITPLW-- 423
SQ PE G G VE P P+ QP L P+ PL
Sbjct: 1138 TSQQPEPVLGLGSVE---------QPHEVPSVLGTPLLQPPENLAKGQPSTPVDRPLGPD 1188
Query: 424 -AAPGR---AARPGRACSAACSEEEDEEDDEEEEDAEDSAGSPGGR-GTGPSA 471
+APG AA P A C ++ +ED E+E+ S G P + G P+A
Sbjct: 1189 PSAPGTLAGAALPPLEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQPAA 1241
Score = 32.0 bits (71), Expect = 2.3
Identities = 29/104 (27%), Positives = 42/104 (40%), Gaps = 8/104 (7%)
Query: 268 NSIEEASSPASEPEPPREPPRRPAFLPVGPDDTNSEYESGSESEPDLSEDADSPWLLSNL 327
+S+E+ P S PP + +PA V T +G P +S SP L +
Sbjct: 1217 DSVEDEEPPGSLGLPPPQAGVQPAAAAVS--GTTQPLGTG----PRVSLSPHSPLLSPKV 1270
Query: 328 VSRMISEGSSPIRCPGQCLSPAPRPPGEPVSPAGGAAQDSQDPE 371
S + + I P C P P P P P G +A + Q+ E
Sbjct: 1271 ASMDAKDLALQILPP--CQVPPPSGPQSPAGPQGLSAPEQQEDE 1312
>gi|239749105 PREDICTED: NAC alpha domain containing [Homo sapiens]
Length = 1522
Score = 53.1 bits (126), Expect = 1e-06
Identities = 114/473 (24%), Positives = 170/473 (35%), Gaps = 79/473 (16%)
Query: 14 GLLLPSGPALLSPSVLQDSLSLGRSEQPHPICSFQDDFQEFEMIDDNEEEDDEDEEEEEE 73
GL LP A+ P LQD+ S P P+ + Q+ E +D
Sbjct: 833 GLTLPQDSAMTPPLPLQDT---DLSSAPKPVAAATPVSQQAEE-GLTLPQDSAMTAPLPL 888
Query: 74 EEEGDGEGQEGGDPGSEAPAPGPLIPSPSVEEPHKHRPTTLRLTTLGAQDSLNNNGGFDL 133
++ G G P P + +++ P T + T+ Q+ G
Sbjct: 889 QDTGPTSG----------PEPLAVATPQTLQAEAGCAPGTEPVATMAQQEVGEALGP--- 935
Query: 134 VRPASWQETALCS--PAPEALRELP--GPLPATDTG-PGGAQSPVRPGCDCEGNRPAEPP 188
RPA ++ A P P AL ++ P PA + G P AQ E EP
Sbjct: 936 -RPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSLPEPA 994
Query: 189 APGGTSPS---SDPGIEADLRSRSSGGRGGRRSSQELSSPGSDSEDAGGARLGRMISSIS 245
+ G + S PG EA L +R+ G G + S + + +++ GG + ++
Sbjct: 995 SGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEGG------LKPLA 1048
Query: 246 ETELELSSDGGSSSSGRSSHLTNSIEEASSPASEPEPPREPPRRPAFLPVGPDDTNSEYE 305
+ S+ GG+ E P PP P+ + +
Sbjct: 1049 QEHGPRSALGGAR----------------------EVPDAPPA------ACPEVSQARLL 1080
Query: 306 SGSESEPDLSEDADSPWLLSNLVSRMISEGSSPIRCPGQCLSPAPRPPGEPVSPAGGAAQ 365
S + E LS + L + V+ S S P G +S R G P +PA +A
Sbjct: 1081 SPAREERGLSGKSTPEPTLPSAVATEASLDSCPESSVG-AVSSLDR--GCPDAPAPTSAP 1137
Query: 366 DSQDPEAAAGPGGVELVDMETLCAPPPPAPAAPRPGPAQPGPCLFLSNPTRDTITPLW-- 423
SQ PE G G VE P P+ QP L P+ PL
Sbjct: 1138 TSQQPEPVLGLGSVE---------QPHEVPSVLGTPLLQPPENLAKGQPSTPVDRPLGPD 1188
Query: 424 -AAPGR---AARPGRACSAACSEEEDEEDDEEEEDAEDSAGSPGGR-GTGPSA 471
+APG AA P A C ++ +ED E+E+ S G P + G P+A
Sbjct: 1189 PSAPGTLAGAALPPLEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQPAA 1241
Score = 32.0 bits (71), Expect = 2.3
Identities = 29/104 (27%), Positives = 42/104 (40%), Gaps = 8/104 (7%)
Query: 268 NSIEEASSPASEPEPPREPPRRPAFLPVGPDDTNSEYESGSESEPDLSEDADSPWLLSNL 327
+S+E+ P S PP + +PA V T +G P +S SP L +
Sbjct: 1217 DSVEDEEPPGSLGLPPPQAGVQPAAAAVS--GTTQPLGTG----PRVSLSPHSPLLSPKV 1270
Query: 328 VSRMISEGSSPIRCPGQCLSPAPRPPGEPVSPAGGAAQDSQDPE 371
S + + I P C P P P P P G +A + Q+ E
Sbjct: 1271 ASMDAKDLALQILPP--CQVPPPSGPQSPAGPQGLSAPEQQEDE 1312
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.133 0.403
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 44,380,760
Number of Sequences: 37866
Number of extensions: 3039229
Number of successful extensions: 56939
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 750
Number of HSP's successfully gapped in prelim test: 1678
Number of HSP's that attempted gapping in prelim test: 23977
Number of HSP's gapped (non-prelim): 21842
length of query: 797
length of database: 18,247,518
effective HSP length: 110
effective length of query: 687
effective length of database: 14,082,258
effective search space: 9674511246
effective search space used: 9674511246
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.