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Search of human proteins with 7706156
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7706156 lysine-rich coiled-coil 1 [Homo sapiens]
(259 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7706156 lysine-rich coiled-coil 1 [Homo sapiens] 538 e-153
gi|58533176 zinc finger, matrin type 1 isoform 1 [Homo sapiens] 337 8e-93
gi|58533172 zinc finger, matrin type 1 isoform 3 [Homo sapiens] 337 8e-93
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 52 5e-07
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 51 9e-07
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 51 1e-06
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 48 7e-06
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 48 7e-06
gi|148746195 trichohyalin [Homo sapiens] 47 1e-05
gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens] 47 1e-05
gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens] 47 1e-05
gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo ... 47 2e-05
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 47 2e-05
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 46 3e-05
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 46 3e-05
gi|151301228 formin binding protein 3 [Homo sapiens] 46 3e-05
gi|11225260 DNA topoisomerase I [Homo sapiens] 46 4e-05
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 46 4e-05
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 45 5e-05
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 45 5e-05
gi|168229156 NFKB activating protein [Homo sapiens] 45 6e-05
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 45 6e-05
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 45 6e-05
gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens] 45 8e-05
gi|239752449 PREDICTED: hypothetical protein [Homo sapiens] 44 1e-04
gi|239750213 PREDICTED: hypothetical protein [Homo sapiens] 44 1e-04
gi|21396500 HIRA interacting protein 3 [Homo sapiens] 44 2e-04
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 43 2e-04
gi|155969714 nuclear protein, ataxia-telangiectasia locus [Homo... 43 2e-04
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 43 2e-04
>gi|7706156 lysine-rich coiled-coil 1 [Homo sapiens]
Length = 259
Score = 538 bits (1386), Expect = e-153
Identities = 259/259 (100%), Positives = 259/259 (100%)
Query: 1 MKHSKKTYDSFQDELEDYIKVQKARGLEPKTCFRKMKGDYLETCGYKGEVNSRPTYRMFD 60
MKHSKKTYDSFQDELEDYIKVQKARGLEPKTCFRKMKGDYLETCGYKGEVNSRPTYRMFD
Sbjct: 1 MKHSKKTYDSFQDELEDYIKVQKARGLEPKTCFRKMKGDYLETCGYKGEVNSRPTYRMFD 60
Query: 61 QRLPSETIQTYPRSCNIPQTVENRLPQWLPAHDSRLRLDSLSYCQFTRDCFSEKPVPLNF 120
QRLPSETIQTYPRSCNIPQTVENRLPQWLPAHDSRLRLDSLSYCQFTRDCFSEKPVPLNF
Sbjct: 61 QRLPSETIQTYPRSCNIPQTVENRLPQWLPAHDSRLRLDSLSYCQFTRDCFSEKPVPLNF 120
Query: 121 NQQEYICGSHGVEHRVYKHFSSDNSTSTHQASHKQIHQKRKRHPEEGREKSEEERSKHKR 180
NQQEYICGSHGVEHRVYKHFSSDNSTSTHQASHKQIHQKRKRHPEEGREKSEEERSKHKR
Sbjct: 121 NQQEYICGSHGVEHRVYKHFSSDNSTSTHQASHKQIHQKRKRHPEEGREKSEEERSKHKR 180
Query: 181 KKSCEEIDLDKHKSIQRKKTEVEIETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKE 240
KKSCEEIDLDKHKSIQRKKTEVEIETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKE
Sbjct: 181 KKSCEEIDLDKHKSIQRKKTEVEIETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKE 240
Query: 241 QGQERTEEEMLWDQSILGF 259
QGQERTEEEMLWDQSILGF
Sbjct: 241 QGQERTEEEMLWDQSILGF 259
>gi|58533176 zinc finger, matrin type 1 isoform 1 [Homo sapiens]
Length = 638
Score = 337 bits (863), Expect = 8e-93
Identities = 169/257 (65%), Positives = 203/257 (78%), Gaps = 2/257 (0%)
Query: 3 HSKKTYDSFQDELEDYIKVQKARGLEPKTCFRKMKGDYLETCGYKGEVNSRPTYRMFDQR 62
HSK+TYDSFQDELEDYIKVQKARGLEPKTCFRK+ +ET + V+ RP +RM +Q+
Sbjct: 384 HSKRTYDSFQDELEDYIKVQKARGLEPKTCFRKIGDSSVETHRNREMVDVRPRHRMLEQK 443
Query: 63 LPSETIQTYPRSCNIPQTVENRLPQWLPAHDSRLRLDSLSYCQFTRDCFSEKPVPLNFNQ 122
LP ET QTY +I Q VEN+LP LPAHDS+ RLDS+SYCQ TRDCF EKPVPL+ NQ
Sbjct: 444 LPCETFQTYSGPYSISQVVENQLPHCLPAHDSKQRLDSISYCQLTRDCFPEKPVPLSLNQ 503
Query: 123 QEYICGSHGVEHRVYKHFSSDNSTSTHQASHKQIHQKRKRHPEEGREKSEEERSKHKRKK 182
QE GS+ VE VYKH SS+N+T+ HQA HKQ HQKRKRH EEG+E+ E+E+SKHKRKK
Sbjct: 504 QENNSGSYSVESEVYKHLSSENNTADHQAGHKQKHQKRKRHLEEGKERPEKEQSKHKRKK 563
Query: 183 SCEEIDLDKHKSIQRKKTEVEIETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQG 242
S E+ DLDK KSI+++K E + V VS+ KLK+RK+KKS DV S+KEERK K+KK+
Sbjct: 564 SYEDTDLDKDKSIRQRKREE--DRVKVSSGKLKHRKKKKSHDVPSEKEERKHRKEKKKSV 621
Query: 243 QERTEEEMLWDQSILGF 259
+ERTEEEMLWD+SILGF
Sbjct: 622 EERTEEEMLWDESILGF 638
Score = 121 bits (304), Expect = 5e-28
Identities = 73/165 (44%), Positives = 98/165 (59%), Gaps = 23/165 (13%)
Query: 1 MKHSKKTYDSFQDELEDYIKVQKARGLEPKTCFRKMKGDYLETCGYKGEVNSRPTYRMFD 60
+ HSKKTYDSFQDELEDYIKVQKARGL+PKTCFRKM+ + ++T GY+ V+S P RM +
Sbjct: 294 LPHSKKTYDSFQDELEDYIKVQKARGLDPKTCFRKMRENSVDTHGYREMVDSGPRSRMCE 353
Query: 61 QRLPSETIQTYPRSCNIPQTVENRLPQWLPAHDSRLRLDSLSYCQFTRDCFSEKPVPLNF 120
QR E QTY R +I VE++LPQWLP H R T D F ++
Sbjct: 354 QRFSHEASQTYQRPYHI-SPVESQLPQWLPTHSKR-----------TYDSFQDE------ 395
Query: 121 NQQEYI--CGSHGVEHRVYKHFSSDNSTSTHQASHKQIHQKRKRH 163
++YI + G+E + D+S TH+ ++++ R RH
Sbjct: 396 -LEDYIKVQKARGLEPKTCFRKIGDSSVETHR--NREMVDVRPRH 437
Score = 106 bits (264), Expect = 2e-23
Identities = 53/94 (56%), Positives = 67/94 (71%)
Query: 1 MKHSKKTYDSFQDELEDYIKVQKARGLEPKTCFRKMKGDYLETCGYKGEVNSRPTYRMFD 60
+K+S+KT DS+Q+E DYI VQKARGLE KTCFRKM+ LET Y+ V+SRP +RMF+
Sbjct: 210 VKNSRKTQDSYQNECADYINVQKARGLEAKTCFRKMEESSLETRRYREVVDSRPRHRMFE 269
Query: 61 QRLPSETIQTYPRSCNIPQTVENRLPQWLPAHDS 94
QRLP ET +TY NI Q +E +LP +DS
Sbjct: 270 QRLPFETFRTYAAPYNISQAMEKQLPHSKKTYDS 303
>gi|58533172 zinc finger, matrin type 1 isoform 3 [Homo sapiens]
Length = 467
Score = 337 bits (863), Expect = 8e-93
Identities = 169/257 (65%), Positives = 203/257 (78%), Gaps = 2/257 (0%)
Query: 3 HSKKTYDSFQDELEDYIKVQKARGLEPKTCFRKMKGDYLETCGYKGEVNSRPTYRMFDQR 62
HSK+TYDSFQDELEDYIKVQKARGLEPKTCFRK+ +ET + V+ RP +RM +Q+
Sbjct: 213 HSKRTYDSFQDELEDYIKVQKARGLEPKTCFRKIGDSSVETHRNREMVDVRPRHRMLEQK 272
Query: 63 LPSETIQTYPRSCNIPQTVENRLPQWLPAHDSRLRLDSLSYCQFTRDCFSEKPVPLNFNQ 122
LP ET QTY +I Q VEN+LP LPAHDS+ RLDS+SYCQ TRDCF EKPVPL+ NQ
Sbjct: 273 LPCETFQTYSGPYSISQVVENQLPHCLPAHDSKQRLDSISYCQLTRDCFPEKPVPLSLNQ 332
Query: 123 QEYICGSHGVEHRVYKHFSSDNSTSTHQASHKQIHQKRKRHPEEGREKSEEERSKHKRKK 182
QE GS+ VE VYKH SS+N+T+ HQA HKQ HQKRKRH EEG+E+ E+E+SKHKRKK
Sbjct: 333 QENNSGSYSVESEVYKHLSSENNTADHQAGHKQKHQKRKRHLEEGKERPEKEQSKHKRKK 392
Query: 183 SCEEIDLDKHKSIQRKKTEVEIETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQG 242
S E+ DLDK KSI+++K E + V VS+ KLK+RK+KKS DV S+KEERK K+KK+
Sbjct: 393 SYEDTDLDKDKSIRQRKREE--DRVKVSSGKLKHRKKKKSHDVPSEKEERKHRKEKKKSV 450
Query: 243 QERTEEEMLWDQSILGF 259
+ERTEEEMLWD+SILGF
Sbjct: 451 EERTEEEMLWDESILGF 467
Score = 121 bits (304), Expect = 5e-28
Identities = 73/165 (44%), Positives = 98/165 (59%), Gaps = 23/165 (13%)
Query: 1 MKHSKKTYDSFQDELEDYIKVQKARGLEPKTCFRKMKGDYLETCGYKGEVNSRPTYRMFD 60
+ HSKKTYDSFQDELEDYIKVQKARGL+PKTCFRKM+ + ++T GY+ V+S P RM +
Sbjct: 123 LPHSKKTYDSFQDELEDYIKVQKARGLDPKTCFRKMRENSVDTHGYREMVDSGPRSRMCE 182
Query: 61 QRLPSETIQTYPRSCNIPQTVENRLPQWLPAHDSRLRLDSLSYCQFTRDCFSEKPVPLNF 120
QR E QTY R +I VE++LPQWLP H R T D F ++
Sbjct: 183 QRFSHEASQTYQRPYHI-SPVESQLPQWLPTHSKR-----------TYDSFQDE------ 224
Query: 121 NQQEYI--CGSHGVEHRVYKHFSSDNSTSTHQASHKQIHQKRKRH 163
++YI + G+E + D+S TH+ ++++ R RH
Sbjct: 225 -LEDYIKVQKARGLEPKTCFRKIGDSSVETHR--NREMVDVRPRH 266
Score = 106 bits (264), Expect = 2e-23
Identities = 53/94 (56%), Positives = 67/94 (71%)
Query: 1 MKHSKKTYDSFQDELEDYIKVQKARGLEPKTCFRKMKGDYLETCGYKGEVNSRPTYRMFD 60
+K+S+KT DS+Q+E DYI VQKARGLE KTCFRKM+ LET Y+ V+SRP +RMF+
Sbjct: 39 VKNSRKTQDSYQNECADYINVQKARGLEAKTCFRKMEESSLETRRYREVVDSRPRHRMFE 98
Query: 61 QRLPSETIQTYPRSCNIPQTVENRLPQWLPAHDS 94
QRLP ET +TY NI Q +E +LP +DS
Sbjct: 99 QRLPFETFRTYAAPYNISQAMEKQLPHSKKTYDS 132
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 52.0 bits (123), Expect = 5e-07
Identities = 33/96 (34%), Positives = 51/96 (53%), Gaps = 8/96 (8%)
Query: 154 KQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVSTEK 213
K+ +K EE E EEE + KRK+ +E K K ++KK E E E+
Sbjct: 3 KKKKKKETEETEETEETEEEEEKEGKRKEKRKE----KRKEKEKKKKTKETEKRKEKEEE 58
Query: 214 LKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEEE 249
K RK K+ + KKEE +R ++++E+ +E+ EEE
Sbjct: 59 EKKRKRKRKK----KKEEEEREEEEEEEEEEKEEEE 90
Score = 48.9 bits (115), Expect = 4e-06
Identities = 24/86 (27%), Positives = 47/86 (54%)
Query: 154 KQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVSTEK 213
K+ +K+K E R++ EEE K KRK+ ++ + ++ + + ++ E E E +
Sbjct: 38 KEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRR 97
Query: 214 LKNRKEKKSRDVVSKKEERKRTKKKK 239
K +K ++ + KK++R+R KKK
Sbjct: 98 KKKKKRRRKEEEEEKKKKRRRKTKKK 123
Score = 45.4 bits (106), Expect = 5e-05
Identities = 25/104 (24%), Positives = 58/104 (55%), Gaps = 1/104 (0%)
Query: 142 SDNSTSTHQASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTE 201
++ + T + K+ +K KR E+ +EK +++++K K+ +E + K K ++KK E
Sbjct: 13 TEETEETEEEEEKEGKRKEKRK-EKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKE 71
Query: 202 VEIETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQER 245
E E+ + +E+K KK++++R K+++E+ +++
Sbjct: 72 EEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKK 115
Score = 42.4 bits (98), Expect = 4e-04
Identities = 23/92 (25%), Positives = 52/92 (56%), Gaps = 4/92 (4%)
Query: 154 KQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVSTEK 213
K+ +++K+ +E ++ E+E + KRK+ ++ K + +R++ E E E EK
Sbjct: 36 KRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKK----KKEEEEREEEEEEEEEEKEEEEK 91
Query: 214 LKNRKEKKSRDVVSKKEERKRTKKKKEQGQER 245
+ R+ KK + K+EE ++ KK++ + +++
Sbjct: 92 EEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123
Score = 40.0 bits (92), Expect = 0.002
Identities = 21/59 (35%), Positives = 34/59 (57%)
Query: 191 KHKSIQRKKTEVEIETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEEE 249
K K ++K+TE ET E+ K K K+ R K++E+K+ K+ E+ +E+ EEE
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEE 59
Score = 39.7 bits (91), Expect = 0.003
Identities = 23/101 (22%), Positives = 48/101 (47%), Gaps = 15/101 (14%)
Query: 138 KHFSSDNSTSTHQASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQR 197
K T + ++ +++KR + ++K EEER + + ++ E+ + +K + +R
Sbjct: 38 KEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRR 97
Query: 198 KKTEVEIETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKK 238
KK K ++ +K + KK+ R++TKKK
Sbjct: 98 KK---------------KKKRRRKEEEEEKKKKRRRKTKKK 123
Score = 38.9 bits (89), Expect = 0.005
Identities = 24/80 (30%), Positives = 43/80 (53%), Gaps = 12/80 (15%)
Query: 175 RSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVSTEKLKNR-----KEKKSRDVVSKK 229
+ K K+KK EE + + ++TE E E EK K + K+KK+++ +K
Sbjct: 1 KKKKKKKKETEETE-------ETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRK 53
Query: 230 EERKRTKKKKEQGQERTEEE 249
E+ + KK+K + +++ EEE
Sbjct: 54 EKEEEEKKRKRKRKKKKEEE 73
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 51.2 bits (121), Expect = 9e-07
Identities = 30/112 (26%), Positives = 60/112 (53%), Gaps = 4/112 (3%)
Query: 138 KHFSSDNSTSTHQASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQR 197
K + ++ + ++ ++RKR + RE+ +EER K + +K E + K +
Sbjct: 117 KKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERK---ERKKRERKQVGE 173
Query: 198 KKTEVEIETVHVSTEKLKNRKE-KKSRDVVSKKEERKRTKKKKEQGQERTEE 248
K+ E + + ++ +NRKE KK R+ ++E +K KKK+E+ +ER ++
Sbjct: 174 KEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKD 225
Score = 50.4 bits (119), Expect = 1e-06
Identities = 25/89 (28%), Positives = 54/89 (60%), Gaps = 4/89 (4%)
Query: 165 EEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVSTEKLKNRKEKKSRD 224
+EG+++ E ER K +R++ + + +K + +R K E + E E+ K R+EK++++
Sbjct: 49 KEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKE 108
Query: 225 VVSKKEERKRTKKKK----EQGQERTEEE 249
K++ +K+ KK++ ++G+ER +E
Sbjct: 109 GEEKEKRKKKEKKERGRTSKEGKERERKE 137
Score = 50.1 bits (118), Expect = 2e-06
Identities = 32/99 (32%), Positives = 55/99 (55%), Gaps = 7/99 (7%)
Query: 158 QKRKRHPEEGREKSEEERSKHKRKKS---CEEIDLDKHKSIQRKKTE-VEIETVHVSTEK 213
+K++R +E +E E+E+ K K KK + ++ + +RK+ E E E EK
Sbjct: 97 RKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREK 156
Query: 214 LKNRKEKKSRD---VVSKKEERKRTKKKKEQGQERTEEE 249
+ RKE+K R+ V K+EERK ++K+ + +ER +E
Sbjct: 157 ERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKE 195
Score = 47.0 bits (110), Expect = 2e-05
Identities = 36/117 (30%), Positives = 59/117 (50%), Gaps = 11/117 (9%)
Query: 143 DNSTSTHQASHKQIHQKRKRHPEEGREKSEEERSKHKRKK--SCEEIDLDKHKSIQRKKT 200
+ T + K+ +RK+ E REK + ER K ++++ E+ K + +RKK
Sbjct: 42 EREIETRKEGKKERESERKKERRE-REKRKREREKERKRERGKKEKKGERKKEERERKKR 100
Query: 201 EVEIETVHVSTEKLKNRKEKKSRDVVSK-------KEERKR-TKKKKEQGQERTEEE 249
E E ++ + +KEKK R SK KEERKR +K++E+ +E E+E
Sbjct: 101 RREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKE 157
Score = 47.0 bits (110), Expect = 2e-05
Identities = 35/111 (31%), Positives = 54/111 (48%), Gaps = 6/111 (5%)
Query: 141 SSDNSTSTHQASHKQIHQKRKRHPEEGREKSEE--ERSKHKRKKSCEEIDLDKHKSI-QR 197
S + + K+ +K + +E REK E ER K +RK+ E+ + K K +R
Sbjct: 127 SKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKER 186
Query: 198 KKTEVEIETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEE 248
KK E + E+ + R+ KK R KKEERK+ ++K Q R +E
Sbjct: 187 KKRERNRKERKKERERKERRERKKER---KKKEERKKERQKDRQTNWREKE 234
Score = 45.1 bits (105), Expect = 6e-05
Identities = 29/115 (25%), Positives = 64/115 (55%), Gaps = 6/115 (5%)
Query: 138 KHFSSDNSTSTHQASHKQIHQKRKRHPEEGREKSEEERSKHKR--KKSCEEIDLDKHKSI 195
K S+ + ++ ++++R E G+++ + ER K +R KK E + + +
Sbjct: 53 KERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEK 112
Query: 196 QRKKTEVEIETVHVSTE-KLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEEE 249
+++K + + E S E K + RKE++ R+ +++ER+R K+++E+ +ER E +
Sbjct: 113 EKRKKKEKKERGRTSKEGKERERKEERKRE---ERKERERKKEEREKERERKERK 164
Score = 44.7 bits (104), Expect = 8e-05
Identities = 25/96 (26%), Positives = 50/96 (52%), Gaps = 3/96 (3%)
Query: 154 KQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVSTEK 213
K+ ++R R +EG+E+ +E K + +K E ++ K +RK+ + E+
Sbjct: 117 KKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEE 176
Query: 214 LKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEEE 249
+ KE+K R K+E ++ +KK+ + +ER E +
Sbjct: 177 ERKEKERKER---KKRERNRKERKKERERKERRERK 209
Score = 35.4 bits (80), Expect = 0.050
Identities = 21/88 (23%), Positives = 47/88 (53%), Gaps = 14/88 (15%)
Query: 154 KQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVSTEK 213
KQ+ +K EE +EK +ER K +R + + + ++ + +RKK +K
Sbjct: 169 KQVGEKE----EERKEKERKERKKRERNRKERKKERERKERRERKK----------ERKK 214
Query: 214 LKNRKEKKSRDVVSKKEERKRTKKKKEQ 241
+ RK+++ +D + E++R K+++++
Sbjct: 215 KEERKKERQKDRQTNWREKERGKRERKE 242
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 50.8 bits (120), Expect = 1e-06
Identities = 35/102 (34%), Positives = 55/102 (53%), Gaps = 9/102 (8%)
Query: 154 KQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDL----DKHKSIQRKKTEVEI----E 205
K+ +KRK ++ +E+ E+ER K K++K E ++ K +RK+ E E E
Sbjct: 73 KERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRE 132
Query: 206 TVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTE 247
K K RKE+K R+ K ERKR K+KKE+ +++ E
Sbjct: 133 RKRKKRRKKKRRKERK-REKERGKRERKRKKRKKEEREKKRE 173
Score = 49.3 bits (116), Expect = 3e-06
Identities = 25/92 (27%), Positives = 53/92 (57%)
Query: 158 QKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVSTEKLKNR 217
+KR+R E RE+ ++E+ K K+++ +E + + + +++K E E EK K
Sbjct: 46 RKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRE 105
Query: 218 KEKKSRDVVSKKEERKRTKKKKEQGQERTEEE 249
++++ R KK+ERK +++ +Q +ER ++
Sbjct: 106 RKQRGRRERKKKKERKERERENKQRRERKRKK 137
Score = 48.9 bits (115), Expect = 4e-06
Identities = 31/102 (30%), Positives = 56/102 (54%), Gaps = 10/102 (9%)
Query: 148 THQASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETV 207
+ + ++ +KRKR E+ R++ ++ K KRKK ++ K +RK+ E E +
Sbjct: 34 SERKKERREREKRKREREKERKRERGKKEKKKRKKR------ERGKERERKRKEREKQRK 87
Query: 208 HV-STEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEE 248
E+ K +KEKK R+ +K+ +R +KKK++ +ER E
Sbjct: 88 ERREKERRKRKKEKKKRE---RKQRGRRERKKKKERKERERE 126
Score = 48.5 bits (114), Expect = 6e-06
Identities = 30/94 (31%), Positives = 51/94 (54%), Gaps = 8/94 (8%)
Query: 158 QKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDK------HKSIQRKKTEVEIETVHVST 211
++RK E +++ E +R K ++KK +E +K K +RKK E E +
Sbjct: 118 KERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRK 177
Query: 212 EKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQER 245
E+ K R+ K+ R+ KKE +K +KKKE+ ++R
Sbjct: 178 ERKKERERKERRE--RKKERKKERRKKKERKKDR 209
Score = 47.4 bits (111), Expect = 1e-05
Identities = 28/115 (24%), Positives = 56/115 (48%), Gaps = 15/115 (13%)
Query: 138 KHFSSDNSTSTHQASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQR 197
K +N + K+ +KR++ + +E+ + ER + KRKK ++ K +R
Sbjct: 121 KERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKE------EREKKRER 174
Query: 198 KKTEVEIETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEEEMLW 252
+ E +K + RKE++ R KKE RK+ ++KK++ +R + ++
Sbjct: 175 NRKE---------RKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQVF 220
Score = 45.8 bits (107), Expect = 4e-05
Identities = 24/92 (26%), Positives = 53/92 (57%), Gaps = 2/92 (2%)
Query: 158 QKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVSTEKLKNR 217
+K+++ E G+E+ + + + K++K E + K K ++KK E + + +K K R
Sbjct: 63 KKKRKKRERGKERERKRKEREKQRKERREKERRKRKK-EKKKRERK-QRGRRERKKKKER 120
Query: 218 KEKKSRDVVSKKEERKRTKKKKEQGQERTEEE 249
KE++ + ++ +RK+ +KKK + + + E+E
Sbjct: 121 KERERENKQRRERKRKKRRKKKRRKERKREKE 152
Score = 45.4 bits (106), Expect = 5e-05
Identities = 26/86 (30%), Positives = 49/86 (56%), Gaps = 1/86 (1%)
Query: 165 EEGREKSEEERSKHKRKKSCE-EIDLDKHKSIQRKKTEVEIETVHVSTEKLKNRKEKKSR 223
E R+K ER K KR++ E + + K + +RKK E E E+ K RKE++ +
Sbjct: 33 ESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREK 92
Query: 224 DVVSKKEERKRTKKKKEQGQERTEEE 249
+ +K+E+K+ ++K+ +ER +++
Sbjct: 93 ERRKRKKEKKKRERKQRGRRERKKKK 118
Score = 43.9 bits (102), Expect = 1e-04
Identities = 27/108 (25%), Positives = 56/108 (51%), Gaps = 8/108 (7%)
Query: 150 QASHKQIHQKRKRHPEEG-REKSEEERSKHKRKKSCEEIDLD-------KHKSIQRKKTE 201
Q ++ ++RKR E+ RE+ + R + K+KK +E + + K K ++KK
Sbjct: 85 QRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRR 144
Query: 202 VEIETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEEE 249
E + ++ + RK++K + K+E ++ +KK+ + +ER E +
Sbjct: 145 KERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERK 192
Score = 43.1 bits (100), Expect = 2e-04
Identities = 22/92 (23%), Positives = 51/92 (55%), Gaps = 8/92 (8%)
Query: 158 QKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVSTEKLKNR 217
+++K+ + RE+ ++R + KRKK + K +RK+ + E E ++ K +
Sbjct: 113 ERKKKKERKERERENKQRRERKRKK--------RRKKKRRKERKREKERGKRERKRKKRK 164
Query: 218 KEKKSRDVVSKKEERKRTKKKKEQGQERTEEE 249
KE++ + ++ERK+ +++KE+ + + E +
Sbjct: 165 KEEREKKRERNRKERKKERERKERRERKKERK 196
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 48.1 bits (113), Expect = 7e-06
Identities = 31/106 (29%), Positives = 62/106 (58%), Gaps = 5/106 (4%)
Query: 154 KQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVSTEK 213
++IH++ K EE R++ EE + ++ + EEI K K +++K + E V EK
Sbjct: 444 EKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEK 503
Query: 214 LKNRKEK--KSRDVVSKKEERKRTKKKKEQGQE---RTEEEMLWDQ 254
+ +++EK + + + ++EE+ R +++K + QE R +EEM+ +Q
Sbjct: 504 MHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQ 549
Score = 39.7 bits (91), Expect = 0.003
Identities = 27/98 (27%), Positives = 56/98 (57%), Gaps = 4/98 (4%)
Query: 158 QKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEV-EIETVHVSTEKLKN 216
+K + E+ RE+ E+ R + ++ + EE+ +K + ++R++ + E E E++
Sbjct: 314 EKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMW 373
Query: 217 RKEKKSRDVVSKKEERKRTKKKKEQGQERTEEEMLWDQ 254
KE+K R++ K E++ K +EQ ++R EEE + +Q
Sbjct: 374 EKEEKIRELEEKMHEQE---KIREQEEKRQEEEKIREQ 408
Score = 39.7 bits (91), Expect = 0.003
Identities = 30/121 (24%), Positives = 62/121 (51%), Gaps = 17/121 (14%)
Query: 150 QASHKQIHQKRKRHPEEGREKSEEERSKHKRKKS------CEEIDLDKHKSI--QRKKTE 201
+ K Q++ R EE R++ E+ R + KR++ EE ++ + I Q KK
Sbjct: 381 ELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMW 440
Query: 202 VEIETVHVSTEKLKNRKEKKSRDVVSKKEER--------KRTKKKKEQGQERTEEEMLWD 253
+ E +H EK++ ++++ ++ + ++EE+ ++ +K EQ + R +EE +W
Sbjct: 441 RQEEKIH-EQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWR 499
Query: 254 Q 254
Q
Sbjct: 500 Q 500
Score = 39.7 bits (91), Expect = 0.003
Identities = 27/143 (18%), Positives = 68/143 (47%), Gaps = 10/143 (6%)
Query: 120 FNQQEYICGSHGVEHRVYKHFSSDNSTSTHQASHKQIHQKRKRHPEEGREKSEEERSKHK 179
+ Q+E + + + K + + + ++ +K R E+ RE+ E+ R + +
Sbjct: 478 WRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEE 537
Query: 180 RKKSCEEIDLDKHKSI--------QRKKTEVEIETVHVSTEKLKNRKEKKSRDVVSKKEE 231
+ + EE+ ++ + + +++K + E + EK++ +KEK E+
Sbjct: 538 KIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQ 597
Query: 232 RKRTKKKKEQGQERTEEEMLWDQ 254
++ ++++E QE +EE +W+Q
Sbjct: 598 EEKIREQEEMMQE--QEEKMWEQ 618
Score = 37.7 bits (86), Expect = 0.010
Identities = 23/106 (21%), Positives = 59/106 (55%), Gaps = 7/106 (6%)
Query: 158 QKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEV--EIETVHVSTEKLK 215
++ + EE + EE+ + ++ + EE ++ + I+ +K ++ + E + EK++
Sbjct: 543 EEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIR 602
Query: 216 NRKE--KKSRDVVSKKEERKRTKKKKEQGQE---RTEEEMLWDQSI 256
++E ++ + + ++EE+ +++K Q QE R +EE +W+Q +
Sbjct: 603 EQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEV 648
Score = 36.2 bits (82), Expect = 0.029
Identities = 28/112 (25%), Positives = 58/112 (51%), Gaps = 11/112 (9%)
Query: 154 KQIHQKRKRHPEEGREKSEEERSKHKRKKSC-EEIDLDKHKSIQRKKTEVEIETVHVSTE 212
K+ Q+ K +E + + +EE+ + + KK +E + + + I+ ++ E E + E
Sbjct: 410 KRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEE 469
Query: 213 KLK------NRKEK-KSRDVVSKKEERKRTKKKKEQGQE---RTEEEMLWDQ 254
K++ +KEK ++ + K+EE+ +++K QE R +EE +W Q
Sbjct: 470 KIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQ 521
Score = 35.4 bits (80), Expect = 0.050
Identities = 26/107 (24%), Positives = 51/107 (47%), Gaps = 9/107 (8%)
Query: 150 QASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSI---------QRKKT 200
Q Q +K +R E+ RE+ E+ R + ++ + EE ++ + I Q +K
Sbjct: 556 QEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKM 615
Query: 201 EVEIETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTE 247
+ E + EK++ ++EK R E+ R ++++E+ QE E
Sbjct: 616 WEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQE 662
Score = 33.9 bits (76), Expect = 0.15
Identities = 20/92 (21%), Positives = 50/92 (54%), Gaps = 2/92 (2%)
Query: 165 EEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVSTEKLKNRKEK--KS 222
EE + EE+ + ++ + EE ++ K +++K + + + EK++ ++EK +
Sbjct: 376 EEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQ 435
Query: 223 RDVVSKKEERKRTKKKKEQGQERTEEEMLWDQ 254
+ ++EE+ ++K + ++R E+E +W Q
Sbjct: 436 EKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQ 467
Score = 33.9 bits (76), Expect = 0.15
Identities = 23/114 (20%), Positives = 58/114 (50%), Gaps = 7/114 (6%)
Query: 143 DNSTSTHQASHKQIHQKRKRHPEEGREKSEEERSKHKRK---KSCEEIDLDKHKSIQRKK 199
D + K Q+ K +E + + +EE+ + + + + E++ + K +++K
Sbjct: 506 DQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEK 565
Query: 200 TEVEIETVHVSTEKLKNRKEK--KSRDVVSKKEERKRTKKK--KEQGQERTEEE 249
+ E + EK++ +KEK + + + ++EE+ R +++ +EQ ++ E+E
Sbjct: 566 MRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQE 619
Score = 32.3 bits (72), Expect = 0.42
Identities = 25/110 (22%), Positives = 54/110 (49%), Gaps = 11/110 (10%)
Query: 150 QASHKQIHQKRKRHPEEGREKSEEERSKHKRKK--SCEEIDLDKHKSIQRKKTEVEIETV 207
+ K Q+ +E + + +EE K +K EE+ +K + I+ E+E
Sbjct: 332 EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIR------ELEEK 385
Query: 208 HVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQE---RTEEEMLWDQ 254
EK++ ++EK+ + +++E+++ ++ K QE R +EE + +Q
Sbjct: 386 MHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQ 435
Score = 31.6 bits (70), Expect = 0.72
Identities = 21/90 (23%), Positives = 45/90 (50%), Gaps = 7/90 (7%)
Query: 172 EEERSKHKRKKSCEEIDLDKHKSIQR--KKTEVEIETVHVSTEKLKNRKEKKSRDVVSKK 229
EE ++ + EE + + IQ +K + + E + EK++ ++EK R
Sbjct: 286 EENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMW 345
Query: 230 EERKRTKKKKEQGQERTE-----EEMLWDQ 254
E+ ++ ++++E E+ E EEM+W++
Sbjct: 346 EKEEKMRRQEEMMWEKEEKMRRLEEMMWEK 375
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 48.1 bits (113), Expect = 7e-06
Identities = 36/128 (28%), Positives = 61/128 (47%), Gaps = 21/128 (16%)
Query: 139 HFSSDNSTSTHQASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEI-----DLDKHK 193
+ S N K + QK+ E R+K +EE++K ++ K EE+ D K K
Sbjct: 211 NIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQK 270
Query: 194 SIQRK------KTEVEIET--VHVSTEKLK--------NRKEKKSRDVVSKKEERKRTKK 237
QRK K++V ++T + S EK + N +KK +D KK E++ +K
Sbjct: 271 ESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEK 330
Query: 238 KKEQGQER 245
+K++G +
Sbjct: 331 EKKKGPSK 338
Score = 38.1 bits (87), Expect = 0.008
Identities = 25/81 (30%), Positives = 41/81 (50%), Gaps = 3/81 (3%)
Query: 171 SEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVSTEKLKNRKEKKSRDVVSKKE 230
+E++ K+KK ++ +K + + KK TV E L KE++ R K+E
Sbjct: 305 AEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEER---QKRE 361
Query: 231 ERKRTKKKKEQGQERTEEEML 251
E +R K+ +E +R EEE L
Sbjct: 362 EEERIKRLEELEAKRKEEERL 382
Score = 35.8 bits (81), Expect = 0.038
Identities = 21/107 (19%), Positives = 55/107 (51%), Gaps = 1/107 (0%)
Query: 141 SSDNSTSTHQASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKT 200
+S+ T A+ +K+ ++ ++ +EE+ K K+K + +++ + K
Sbjct: 294 ASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKE 353
Query: 201 EVEIETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTE 247
E E + E++K +E +++ ++ E+++ ++KK++ +ER E
Sbjct: 354 EEERQK-REEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKE 399
Score = 35.8 bits (81), Expect = 0.038
Identities = 22/103 (21%), Positives = 54/103 (52%), Gaps = 3/103 (2%)
Query: 149 HQASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVH 208
++ K+ +K+K+ +E +EK +++ K+ +E + +R+K E E
Sbjct: 309 NEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKR 368
Query: 209 VSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEEEML 251
+ + K ++E++ + +K ERK+ K+K+ + + + E ++L
Sbjct: 369 LEELEAKRKEEER---LEQEKRERKKQKEKERKERLKKEGKLL 408
Score = 35.8 bits (81), Expect = 0.038
Identities = 27/109 (24%), Positives = 47/109 (43%), Gaps = 15/109 (13%)
Query: 148 THQASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETV 207
T + ++H + K +PEE E+ EEE + ++ EE E E E
Sbjct: 515 TEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEE--------------EGESEGS 560
Query: 208 HVSTEKLKNRKEKKSRDVVSKKEERKRTKKKK-EQGQERTEEEMLWDQS 255
E K EK S + KK ++ + + + +RT+EE +D++
Sbjct: 561 EGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTKEERAYDKA 609
Score = 35.4 bits (80), Expect = 0.050
Identities = 19/90 (21%), Positives = 49/90 (54%), Gaps = 4/90 (4%)
Query: 165 EEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVSTEKLKNRKEKKSRD 224
E+ +KS+ ++ K K+K+ +E D+ K + ++ +E + + E + + + + +
Sbjct: 34 EQEPQKSKGKKKKEKKKQDFDEDDILK----ELEELSLEAQGIKADRETVAVKPTENNEE 89
Query: 225 VVSKKEERKRTKKKKEQGQERTEEEMLWDQ 254
+ K+++K+ +K K+Q + + E L D+
Sbjct: 90 EFTSKDKKKKGQKGKKQSFDDNDSEELEDK 119
Score = 33.1 bits (74), Expect = 0.25
Identities = 19/76 (25%), Positives = 40/76 (52%), Gaps = 6/76 (7%)
Query: 169 EKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVSTEKLKNRKEKKSRDVVSK 228
++ E ++SK K+KK ++ D D+ ++ E+E + + + +K +E +
Sbjct: 33 KEQEPQKSKGKKKKEKKKQDFDEDDILK------ELEELSLEAQGIKADRETVAVKPTEN 86
Query: 229 KEERKRTKKKKEQGQE 244
EE +K KK++GQ+
Sbjct: 87 NEEEFTSKDKKKKGQK 102
Score = 32.0 bits (71), Expect = 0.55
Identities = 27/104 (25%), Positives = 44/104 (42%), Gaps = 10/104 (9%)
Query: 158 QKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVSTEKLKNR 217
+K + +E + K EEE K K I + K+ E + E +K K +
Sbjct: 263 KKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKK 322
Query: 218 KEKKSRDVVSKKEERKRT----------KKKKEQGQERTEEEML 251
EK+ ++ KK K T K++E+ Q+R EEE +
Sbjct: 323 GEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERI 366
Score = 30.8 bits (68), Expect = 1.2
Identities = 21/83 (25%), Positives = 40/83 (48%), Gaps = 7/83 (8%)
Query: 165 EEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVSTEKLKNRKEKKSRD 224
+E K +EE + KR+ EE + + + ++ K+ E E + EK + +K+K+
Sbjct: 345 QEALAKLKEEEERQKRE---EEERIKRLEELEAKRKEEE----RLEQEKRERKKQKEKER 397
Query: 225 VVSKKEERKRTKKKKEQGQERTE 247
K+E K K + + + R E
Sbjct: 398 KERLKKEGKLLTKSQREARARAE 420
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 47.4 bits (111), Expect = 1e-05
Identities = 26/112 (23%), Positives = 67/112 (59%), Gaps = 11/112 (9%)
Query: 149 HQASHKQIH--QKRKRHPEEGRE--KSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEI 204
H+ H+Q Q+ KR EE R+ K EEE +H++++ +++ D+ + +R++ +++
Sbjct: 434 HEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEE--ERRERWLKL 491
Query: 205 ETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEEEMLWDQSI 256
E E+ + ++E++ + + ++EER+ + K+++ +ER ++ + +Q +
Sbjct: 492 E-----EEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQL 538
Score = 44.3 bits (103), Expect = 1e-04
Identities = 28/107 (26%), Positives = 60/107 (56%), Gaps = 4/107 (3%)
Query: 150 QASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDK--HKSIQRKKTEVEIETV 207
Q ++ +KR+ + EK +EE + +R+ EE L K + ++R++ E E +
Sbjct: 239 QEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQ 298
Query: 208 HVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEEEMLWDQ 254
+ E+ RK+++ R ++EER+ ++++EQ +ER E+++ +Q
Sbjct: 299 RLRREQQLRRKQEEERR--EQQEERREQQERREQQEERREQQLRREQ 343
Score = 42.4 bits (98), Expect = 4e-04
Identities = 25/114 (21%), Positives = 63/114 (55%), Gaps = 8/114 (7%)
Query: 143 DNSTSTHQASHKQIHQKRKRHPEEGREK----SEEERSKHKRKKSCE---EIDLDKHKSI 195
+ T H+ ++ KR + EE RE+ EEER + + ++ + E + + + +
Sbjct: 461 EEETERHEQERRKQQLKRDQE-EERRERWLKLEEEERREQQERREQQLRREQEERREQRL 519
Query: 196 QRKKTEVEIETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEEE 249
+R++ E ++ S ++L+ +E++ ++ ++EE++ ++++EQ +R +EE
Sbjct: 520 KRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEE 573
Score = 42.0 bits (97), Expect = 5e-04
Identities = 34/164 (20%), Positives = 73/164 (44%), Gaps = 10/164 (6%)
Query: 87 QWLPAHDSRLRLDSLSYCQFTRDCFSEKPVPLNFNQQEYICGSHGVEHRVYKHFSSDNST 146
QW P ++ +R D+ YC+ + F Q E + +H +
Sbjct: 1226 QWEPEKENAVR-DNKVYCKGREN--------EQFRQLEDSQLRDRQSQQDLQHLLGEQQE 1276
Query: 147 STHQASHKQIHQKRKRHPEEGR-EKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIE 205
+ ++ Q+ + PEE + E+ E++ +K + +KS EE L + + ++++ +
Sbjct: 1277 RDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDR 1336
Query: 206 TVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEEE 249
+ L+ R+E+ R ++ R+ + +EQG++ EEE
Sbjct: 1337 KFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEE 1380
Score = 41.6 bits (96), Expect = 7e-04
Identities = 23/98 (23%), Positives = 54/98 (55%), Gaps = 1/98 (1%)
Query: 154 KQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKH-KSIQRKKTEVEIETVHVSTE 212
+Q+ ++++ E+ ++ EEE +R +S +++ ++ + Q K E E E
Sbjct: 505 QQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERRE 564
Query: 213 KLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEEEM 250
+ R++++ RD + K+EE +R ++ K + +ER E+ +
Sbjct: 565 QRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRL 602
Score = 40.0 bits (92), Expect = 0.002
Identities = 25/92 (27%), Positives = 51/92 (55%), Gaps = 6/92 (6%)
Query: 158 QKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVSTEKLKNR 217
Q R+R E R K EE+ + +R++ ++ K ++++T + E EKL+
Sbjct: 209 QLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKE-----EEKLQEE 263
Query: 218 KEKKSRDVVSKKEERKRTKKKKEQGQERTEEE 249
+ ++ R+ + ++EE+ R +++E +ER EEE
Sbjct: 264 EPQRQRE-LQEEEEQLRKLERQELRRERQEEE 294
Score = 40.0 bits (92), Expect = 0.002
Identities = 23/107 (21%), Positives = 57/107 (53%), Gaps = 12/107 (11%)
Query: 150 QASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHV 209
+ ++ Q+R R ++ R K EEER + + ++ + +R++ + E +
Sbjct: 289 ERQEEEQQQQRLRREQQLRRKQEEERREQQE---------ERREQQERREQQEERREQQL 339
Query: 210 STEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEEEMLWDQSI 256
E+ + R+++ R+ ++EER+ + ++EQ +ER E+++ +Q +
Sbjct: 340 RREQEERREQQLRRE---QEEERREQQLRREQEEERREQQLRREQQL 383
Score = 39.7 bits (91), Expect = 0.003
Identities = 26/116 (22%), Positives = 56/116 (48%), Gaps = 15/116 (12%)
Query: 154 KQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEID--LDKHKSIQRKKTEVEIETVHVST 211
K Q+ +R + RE+ E + KR++ E ++ L + +R++ E+ E +
Sbjct: 635 KSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQAR 694
Query: 212 EKLKNRKEKKSRDVVS-------------KKEERKRTKKKKEQGQERTEEEMLWDQ 254
E++K+R K + S +K+E +R ++++E+ + R E E+ W +
Sbjct: 695 ERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQE 750
Score = 39.3 bits (90), Expect = 0.003
Identities = 28/109 (25%), Positives = 55/109 (50%), Gaps = 17/109 (15%)
Query: 158 QKRKRHPEEGRE---KSEEERSKHKRKKSCEE-------------IDLDKHKSIQRKKTE 201
Q+ KR EE R+ K EEER + + K+ EE ++ ++ + QR K E
Sbjct: 565 QRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERRE-QRLKRE 623
Query: 202 VEIETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEEEM 250
E K + ++E++ + + +++ER+ + K+E+ +ER E+ +
Sbjct: 624 EPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRL 672
Score = 38.9 bits (89), Expect = 0.005
Identities = 26/99 (26%), Positives = 53/99 (53%), Gaps = 5/99 (5%)
Query: 158 QKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVSTEKLKNR 217
+++ R ++ R + EEER + K ++ E L + + +R + E ET E+ R
Sbjct: 416 EQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQER---R 472
Query: 218 KEKKSRDVVSKKEER--KRTKKKKEQGQERTEEEMLWDQ 254
K++ RD ++ ER K ++++ + QER E+++ +Q
Sbjct: 473 KQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQ 511
Score = 37.4 bits (85), Expect = 0.013
Identities = 29/122 (23%), Positives = 57/122 (46%), Gaps = 6/122 (4%)
Query: 133 EHRVYKHFSSDNSTSTHQASHKQIHQKR---KRHPEEGRE---KSEEERSKHKRKKSCEE 186
E R+ + S+ Q ++ KR KR +E RE K E+E + + K EE
Sbjct: 525 EERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEE 584
Query: 187 IDLDKHKSIQRKKTEVEIETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERT 246
+ K Q ++ E ++ V + + R+E++ + ++E R++ K +EQ + R
Sbjct: 585 RRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQ 644
Query: 247 EE 248
++
Sbjct: 645 QQ 646
Score = 37.0 bits (84), Expect = 0.017
Identities = 22/98 (22%), Positives = 56/98 (57%), Gaps = 3/98 (3%)
Query: 158 QKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVSTEKLKNR 217
+KR+RH + +E+ K ++ EE +L + + +R++ E E + + E+L+
Sbjct: 882 RKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQ--YREEEQLQQE 939
Query: 218 KEKKSRDVVSKKEERKRTKK-KKEQGQERTEEEMLWDQ 254
+E+ R+ K+ ++R ++ +K++ ++ EE++L ++
Sbjct: 940 EEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEE 977
Score = 36.6 bits (83), Expect = 0.022
Identities = 25/92 (27%), Positives = 49/92 (53%), Gaps = 6/92 (6%)
Query: 158 QKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVSTEKLKNR 217
Q+R R ++ R + EE R + +++ EE L++ + QR K E E + LK
Sbjct: 529 QQRLRSEQQLRREQEERREQLLKRE--EEKRLEQERREQRLKREQEERR----DQLLKRE 582
Query: 218 KEKKSRDVVSKKEERKRTKKKKEQGQERTEEE 249
+E++ + + ++EER + K+E+ + +EE
Sbjct: 583 EERRQQRLKREQEERLEQRLKREEVERLEQEE 614
Score = 36.6 bits (83), Expect = 0.022
Identities = 23/117 (19%), Positives = 59/117 (50%), Gaps = 8/117 (6%)
Query: 143 DNSTSTHQASHKQIHQKRKRHPEEGR--EKSEEERSKHKRKKSC---EEIDLDKHKSI-- 195
+ T Q +Q ++ + EE + + E+R + +R++ C EE+ ++ + +
Sbjct: 1067 ERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLRE 1126
Query: 196 -QRKKTEVEIETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEEEML 251
+ K+ E+E + E+++ +E+ R+ K+ ++ ++ +E+ + + EEE L
Sbjct: 1127 EREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQL 1183
Score = 36.2 bits (82), Expect = 0.029
Identities = 21/102 (20%), Positives = 57/102 (55%), Gaps = 3/102 (2%)
Query: 152 SHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVST 211
S +Q+ ++++ E+ ++ EE+R + +R++ + + ++ + Q K E E +
Sbjct: 534 SEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRD-QLLKREEERRQQRLKR 592
Query: 212 EKLKNRKEKKSRDVVSK--KEERKRTKKKKEQGQERTEEEML 251
E+ + +++ R+ V + +EER+ + K+E+ +E +++L
Sbjct: 593 EQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLL 634
Score = 35.4 bits (80), Expect = 0.050
Identities = 23/106 (21%), Positives = 54/106 (50%), Gaps = 7/106 (6%)
Query: 150 QASHKQIHQKRKRHPEEGRE----KSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIE 205
Q ++ Q+R+ EE RE + +EER + + ++ EE ++ + R++ E E
Sbjct: 317 QQEERREQQERREQQEERREQQLRREQEERREQQLRREQEE---ERREQQLRREQEEERR 373
Query: 206 TVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEEEML 251
+ E+ R+++ R+ ++E++ R +++ + Q+ E+ L
Sbjct: 374 EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQL 419
Score = 35.0 bits (79), Expect = 0.065
Identities = 24/131 (18%), Positives = 60/131 (45%), Gaps = 7/131 (5%)
Query: 133 EHRVYKHFSSDNSTSTHQASHKQIHQKRKRHPEEGREKSEEE-------RSKHKRKKSCE 185
+ RV++ K+ + ++ P+ RE EEE R + +R++ E
Sbjct: 234 QDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEE 293
Query: 186 EIDLDKHKSIQRKKTEVEIETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQER 245
E + + Q+ + + E E E+ + ++ ++ ++ +++ R+ ++++EQ R
Sbjct: 294 EQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRR 353
Query: 246 TEEEMLWDQSI 256
+EE +Q +
Sbjct: 354 EQEEERREQQL 364
Score = 35.0 bits (79), Expect = 0.065
Identities = 24/99 (24%), Positives = 52/99 (52%), Gaps = 11/99 (11%)
Query: 154 KQIHQKRKRHPEEGREKSE--EERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVST 211
+++ Q+ KR E E+ E E+R K EE + ++ + + + + + E +
Sbjct: 596 ERLEQRLKREEVERLEQEERREQRLKR------EEPEEERRQQLLKSEEQEERRQQQLRR 649
Query: 212 EKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEEEM 250
E+ + R+++ R+ ++EER + K+E +ER E+E+
Sbjct: 650 EQQERREQRLKRE---EEEERLEQRLKREHEEERREQEL 685
Score = 35.0 bits (79), Expect = 0.065
Identities = 21/98 (21%), Positives = 52/98 (53%), Gaps = 2/98 (2%)
Query: 151 ASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVS 210
A +Q+ ++++ EE E EER K +R++ +E + + +Q+++ ++ E
Sbjct: 894 ALQEQLRKEQQLLQEEEEELQREEREKRRRQE--QERQYREEEQLQQEEEQLLREEREKR 951
Query: 211 TEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEE 248
+ + R+ +K + + K+E+ + +K + QER ++
Sbjct: 952 RRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKK 989
Score = 35.0 bits (79), Expect = 0.065
Identities = 20/90 (22%), Positives = 47/90 (52%), Gaps = 3/90 (3%)
Query: 158 QKRKRHPEEGREKSEEE---RSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVSTEKL 214
Q+R+ EE ++ EE+ + KR++ E K K +Q+K+ ++ E +
Sbjct: 926 QERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQE 985
Query: 215 KNRKEKKSRDVVSKKEERKRTKKKKEQGQE 244
+ +K ++ ++ ++E+ R +++K + QE
Sbjct: 986 REKKYREEEELQQEEEQLLREEREKRRRQE 1015
Score = 34.7 bits (78), Expect = 0.085
Identities = 26/108 (24%), Positives = 55/108 (50%), Gaps = 8/108 (7%)
Query: 150 QASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCE--EIDLDKHKSIQRKKTEVEIETV 207
Q +Q ++ ++ E + + E+E +H++K E E L + + +R + E ET
Sbjct: 406 QLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETE 465
Query: 208 HVSTEKLKNR------KEKKSRDVVSKKEERKRTKKKKEQGQERTEEE 249
E+ K + +E++ R + ++EER+ ++++EQ R +EE
Sbjct: 466 RHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEE 513
Score = 34.7 bits (78), Expect = 0.085
Identities = 24/103 (23%), Positives = 52/103 (50%), Gaps = 6/103 (5%)
Query: 154 KQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEI----ETVHV 209
++ +KR+R E + + EEE + + + EE + + + ++R+ E E E +
Sbjct: 1125 REEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLL 1184
Query: 210 STEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEEEMLW 252
E+ K R+E++ + ++EE +R K+K+ E ++ W
Sbjct: 1185 REEQEKRRQERERQ--YREEEELQRQKRKQRYRDEDQRSDLKW 1225
Score = 34.7 bits (78), Expect = 0.085
Identities = 22/97 (22%), Positives = 53/97 (54%), Gaps = 6/97 (6%)
Query: 159 KRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVSTEKLKNRK 218
+R+ + RE+ ++ R + + +K +E + + ++RK E E + TE+ + R+
Sbjct: 1685 RRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREE--EQLRQETEQEQLRR 1742
Query: 219 EKKSRDVVSKKEERKRTKKKKEQGQER----TEEEML 251
+++ R ++ +++ R ++++ + QER EEE L
Sbjct: 1743 QERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQL 1779
Score = 34.3 bits (77), Expect = 0.11
Identities = 28/117 (23%), Positives = 55/117 (47%), Gaps = 18/117 (15%)
Query: 150 QASHKQIHQKRKRHPEEGREKSEEERS-----------KHKRKKSCEEIDLDKHKSIQRK 198
Q ++ ++ RH E+GR+ EEE+ K +++ C+E + + RK
Sbjct: 1356 QERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRK 1415
Query: 199 KTEVEIETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQER----TEEEML 251
E E +S ++ + ++ + V ++ ERK +++++ QER EEE L
Sbjct: 1416 FRE---EEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQL 1469
Score = 34.3 bits (77), Expect = 0.11
Identities = 24/116 (20%), Positives = 56/116 (48%), Gaps = 8/116 (6%)
Query: 138 KHFSSDNSTSTHQASHKQIHQKRKRHPEEGRE--KSEEERSKHKRKKSCEEIDLDKHKSI 195
+ F D Q +Q+ Q+R R E + + EE+ H++++ + L++ +
Sbjct: 1595 RKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQER--DRKFLEEEPQL 1652
Query: 196 QRKKTEVEIETVHVSTEKLKNRKE--KKSRDVVSKKEERKRTKKKKEQGQERTEEE 249
+R++ E ++ H K + ++ ++ + +++ER R +++EQ R E E
Sbjct: 1653 RRQEREQQLR--HDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERE 1706
Score = 33.5 bits (75), Expect = 0.19
Identities = 26/117 (22%), Positives = 55/117 (47%), Gaps = 14/117 (11%)
Query: 149 HQASHKQIHQKRKRHPEEGREKSEEERSK---HKRKKSCEEIDLDKHKSIQR-------- 197
H K Q++ R ++ ++ EEE + KR++ +E + + +Q+
Sbjct: 887 HTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLRE 946
Query: 198 ---KKTEVEIETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEEEML 251
K+ E E + +KL+ ++E+ + K+ ++R KK +E+ + + EEE L
Sbjct: 947 EREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQL 1003
Score = 33.1 bits (74), Expect = 0.25
Identities = 26/127 (20%), Positives = 57/127 (44%), Gaps = 22/127 (17%)
Query: 150 QASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCE--EIDLDKHKSIQRKKTEVEIETV 207
Q ++ Q+ +R +E RE+ EE R + R++ E E L + + +R++ ++ E
Sbjct: 310 QEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQE 369
Query: 208 HVSTEKLKNRKEKKSRDVVSKKEERKRTKK--------------------KKEQGQERTE 247
E+ R+++ R+ ++E++ R ++ ++EQ R +
Sbjct: 370 EERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQ 429
Query: 248 EEMLWDQ 254
EE +Q
Sbjct: 430 EEERHEQ 436
Score = 33.1 bits (74), Expect = 0.25
Identities = 22/95 (23%), Positives = 48/95 (50%), Gaps = 3/95 (3%)
Query: 158 QKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVSTEKLKNR 217
Q+ +R + RE+ EE R + R++ EE + + Q+ + E ++ + + R
Sbjct: 343 QEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLR 402
Query: 218 KEKKSRDVVSKKEE---RKRTKKKKEQGQERTEEE 249
+E++ R + E R+ + ++EQ +ER E++
Sbjct: 403 REQQLRREQQLRREQQLRREQQLRREQEEERHEQK 437
Score = 33.1 bits (74), Expect = 0.25
Identities = 21/98 (21%), Positives = 51/98 (52%), Gaps = 5/98 (5%)
Query: 154 KQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVSTEK 213
+++ Q+ +R RE+ EEER + K +E + + Q ++ + E + E+
Sbjct: 608 ERLEQEERREQRLKREEPEEERRQQLLKSEEQE----ERRQQQLRREQQERREQRLKREE 663
Query: 214 LKNRKEKK-SRDVVSKKEERKRTKKKKEQGQERTEEEM 250
+ R E++ R+ ++ E++ ++++EQ +ER + +
Sbjct: 664 EEERLEQRLKREHEEERREQELAEEEQEQARERIKSRI 701
Score = 33.1 bits (74), Expect = 0.25
Identities = 28/115 (24%), Positives = 61/115 (53%), Gaps = 12/115 (10%)
Query: 150 QASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKK--TEVEIETV 207
Q ++ Q+ +R E EK E+R + +R++ E L++ + +QR++ +++ E
Sbjct: 797 QLRAEERQQREQRFLPEEEEK--EQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEED 854
Query: 208 HVSTEKLKNRKEKKSRDVVSK---KEERKRTK-----KKKEQGQERTEEEMLWDQ 254
+ ++ + R +++ RD + +EERKR + K Q Q R E+++L ++
Sbjct: 855 GLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEE 909
Score = 33.1 bits (74), Expect = 0.25
Identities = 28/115 (24%), Positives = 57/115 (49%), Gaps = 15/115 (13%)
Query: 158 QKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQR---KKTEVEIETVHV-STEK 213
+KR+R E + + EEE + + + EE + + + +R KK E++ E + E+
Sbjct: 979 EKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREER 1038
Query: 214 LKNRKEKKSRDVVSKKE----------ERKRTKKKKE-QGQERTEEEMLWDQSIL 257
K R +++ R ++E E + T++++E + Q R EEE+ ++ L
Sbjct: 1039 EKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQL 1093
Score = 32.7 bits (73), Expect = 0.32
Identities = 25/119 (21%), Positives = 60/119 (50%), Gaps = 15/119 (12%)
Query: 154 KQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQR---KKTEVEIETVHVS 210
++ +KR+ E + + EEE + + + EE + + + ++R K+ E++ E +
Sbjct: 1035 REEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLL 1094
Query: 211 TEKL-KNRKEKKSRDVVSK-----------KEERKRTKKKKEQGQERTEEEMLWDQSIL 257
E+ K R++++ R + +EER++ ++++ + Q R EEE+ ++ L
Sbjct: 1095 REEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQL 1153
Score = 31.2 bits (69), Expect = 0.94
Identities = 23/97 (23%), Positives = 51/97 (52%), Gaps = 5/97 (5%)
Query: 158 QKRKRHPEEGREKSEEERSKHKRKKSCE-EIDLDKHKSIQRKKTEVEIETVHVST--EKL 214
Q+ +R + RE+ + +R++ E L + + ++R++ E E H E+
Sbjct: 387 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQR 446
Query: 215 KNRKEKKSRDVVSKKEERKR--TKKKKEQGQERTEEE 249
R++++ RD + ++EE +R +++K+Q + EEE
Sbjct: 447 LKREQEERRDWLKREEETERHEQERRKQQLKRDQEEE 483
Score = 31.2 bits (69), Expect = 0.94
Identities = 18/91 (19%), Positives = 46/91 (50%)
Query: 158 QKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVSTEKLKNR 217
++ KR +E + +++ ++++ + +K + +R+K E E + E+L
Sbjct: 947 EREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLRE 1006
Query: 218 KEKKSRDVVSKKEERKRTKKKKEQGQERTEE 248
+ +K R +++ RK+ + ++E+ Q EE
Sbjct: 1007 EREKRRRQEWERQYRKKDELQQEEEQLLREE 1037
Score = 31.2 bits (69), Expect = 0.94
Identities = 26/110 (23%), Positives = 55/110 (50%), Gaps = 8/110 (7%)
Query: 150 QASHKQIHQKRKRHPEEGREKSEE--ERSKHKR-KKSCEEIDLDKH-----KSIQRKKTE 201
Q +Q + +K +E + EE +R + +R KK EE +L + + + K+
Sbjct: 954 QERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRR 1013
Query: 202 VEIETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEEEML 251
E E + ++L+ +E+ R+ K+ ++R ++ +E+ + + EEE L
Sbjct: 1014 QEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQL 1063
Score = 30.8 bits (68), Expect = 1.2
Identities = 21/112 (18%), Positives = 52/112 (46%), Gaps = 2/112 (1%)
Query: 138 KHFSSDNSTSTHQASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQR 197
+ F + Q ++ ++ R E R+ EEE+ H++++ + + ++ Q
Sbjct: 1485 RKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQE 1544
Query: 198 KKTEVEIETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEEE 249
+ + + E+ + R+E++ + + ++ER R + +EQ R E+E
Sbjct: 1545 RGQQRRQDRDRKFREEEQLRQEREEQQL--SRQERDRKFRLEEQKVRRQEQE 1594
Score = 30.0 bits (66), Expect = 2.1
Identities = 24/121 (19%), Positives = 54/121 (44%), Gaps = 17/121 (14%)
Query: 146 TSTHQASHKQIHQKRKRHPEEGREKSE------EERSKHKRKKSCE---------EIDLD 190
+ + KQ Q+R++ EE R + E EE H++++ E + +
Sbjct: 717 SKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEK 776
Query: 191 KHKSIQRKKTEVEIETVHVSTEKLKNRKEKKSRDV--VSKKEERKRTKKKKEQGQERTEE 248
+ QR + + + R++++ R + +KE+R+R ++++E+ + EE
Sbjct: 777 SERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEE 836
Query: 249 E 249
E
Sbjct: 837 E 837
Score = 30.0 bits (66), Expect = 2.1
Identities = 28/116 (24%), Positives = 57/116 (49%), Gaps = 14/116 (12%)
Query: 150 QASHKQIHQKRKRHPEEG---REKSEEERSKHKRKKSCEEIDLDKHKSI-----QRKKTE 201
Q +Q +K + EE RE+ E+ R + + ++ EE +L + + + +
Sbjct: 1014 QEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRR 1073
Query: 202 VEIETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEEEMLWDQSIL 257
E+E + E+L+ +E+ R+ E KR ++++E+ Q R EEE+ ++ L
Sbjct: 1074 QELERQYRKEEELQQEEEQLLRE-----EPEKRRRQERER-QCREEEELQQEEEQL 1123
Score = 30.0 bits (66), Expect = 2.1
Identities = 21/122 (17%), Positives = 59/122 (48%), Gaps = 3/122 (2%)
Query: 120 FNQQEYICGSHGVEHRVYKHFSSDNSTSTHQASHKQIHQKRKRHPEEGREKSEEERSKHK 179
F ++E + G E ++ + Q +Q +++ E+ + E ER +
Sbjct: 1669 FREEEQLL-QEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFRE 1727
Query: 180 RKKSCEEIDLDKHKSIQRKKTEVEIETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKK 239
++ +E + ++ + +R + +E E + E+ + R++++ R ++EE+ R ++++
Sbjct: 1728 EEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKF--REEEQLRQEREE 1785
Query: 240 EQ 241
+Q
Sbjct: 1786 QQ 1787
Score = 29.6 bits (65), Expect = 2.7
Identities = 18/87 (20%), Positives = 40/87 (45%), Gaps = 9/87 (10%)
Query: 165 EEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVSTEKLKNRKEKKSRD 224
++ R +S+E+R K + EE +RK+ + E+L+ ++ +
Sbjct: 859 DQERRRSQEQRRDQKWRWQLEE---------ERKRRRHTLYAKPALQEQLRKEQQLLQEE 909
Query: 225 VVSKKEERKRTKKKKEQGQERTEEEML 251
+ E + ++++EQ ++ EEE L
Sbjct: 910 EEELQREEREKRRRQEQERQYREEEQL 936
Score = 29.6 bits (65), Expect = 2.7
Identities = 21/100 (21%), Positives = 52/100 (52%), Gaps = 2/100 (2%)
Query: 154 KQIHQKRKRHPEEGREKSEEERSKHKRKKSCE-EIDLDKHKSIQRKKTEVEIETVHVSTE 212
++ Q R+ + R++ ++ +H + E + + ++ + QR + E E + +
Sbjct: 1245 RENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQ 1304
Query: 213 KLKNRKEKKSRDVVSK-KEERKRTKKKKEQGQERTEEEML 251
K R+++KS++ +EER+ ++++E ++ EEE L
Sbjct: 1305 KEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQL 1344
Score = 29.6 bits (65), Expect = 2.7
Identities = 22/100 (22%), Positives = 49/100 (49%), Gaps = 5/100 (5%)
Query: 154 KQIHQKRKR--HPEEGREKSEEERSKHKR---KKSCEEIDLDKHKSIQRKKTEVEIETVH 208
+Q+ Q+R R EE + EE+ H++ +K EE + + RK E E+ +
Sbjct: 1453 QQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQE 1512
Query: 209 VSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEE 248
+ L+ ++ + K + ++ +++E+GQ+R ++
Sbjct: 1513 PERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQD 1552
Score = 29.3 bits (64), Expect = 3.6
Identities = 22/94 (23%), Positives = 48/94 (51%), Gaps = 3/94 (3%)
Query: 159 KRKRHPEEGREKSEEERSKHKRKKSCEEID--LDKHKSIQRKKTEVEIETVHVSTEKLKN 216
+ KR +G+E ++R + + ++ E D L++ +R++ E E E+
Sbjct: 97 EEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSE 156
Query: 217 RKEK-KSRDVVSKKEERKRTKKKKEQGQERTEEE 249
++E+ + RD + EE R +++ ++ +ER EE
Sbjct: 157 KQERLEQRDRQRRDEELWRQRQEWQEREERRAEE 190
Score = 29.3 bits (64), Expect = 3.6
Identities = 23/104 (22%), Positives = 55/104 (52%), Gaps = 6/104 (5%)
Query: 154 KQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVSTEK 213
+Q ++ R E R + E ER ++++K ++ + + + K+ E E + E+
Sbjct: 997 QQEEEQLLREEREKRRRQEWER-QYRKKDELQQEEEQLLREEREKRRLQERERQYREEEE 1055
Query: 214 LKNRKEK---KSRDVVSKKEERKRTKKKKEQGQERTEEEMLWDQ 254
L+ +E+ + R+ ++E ++ +K++E QE EE++L ++
Sbjct: 1056 LQQEEEQLLGEERETRRRQELERQYRKEEELQQE--EEQLLREE 1097
Score = 29.3 bits (64), Expect = 3.6
Identities = 23/103 (22%), Positives = 48/103 (46%), Gaps = 8/103 (7%)
Query: 158 QKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQ---RKKTEVEIETVHV---ST 211
Q+++R E + + EEE + KRK+ + D Q K+ V V+
Sbjct: 1188 QEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGREN 1247
Query: 212 EKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEEEMLWDQ 254
E+ + ++ + RD S+++ + +++E ++R +E W Q
Sbjct: 1248 EQFRQLEDSQLRDRQSQQDLQHLLGEQQE--RDREQERRRWQQ 1288
Score = 29.3 bits (64), Expect = 3.6
Identities = 20/107 (18%), Positives = 53/107 (49%), Gaps = 5/107 (4%)
Query: 150 QASHKQIHQKR--KRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETV 207
Q H+Q ++ + P+ R++ E++ + +K EE L + Q+ + +
Sbjct: 1634 QQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKF 1693
Query: 208 HVSTEKLKNRKEKKS---RDVVSKKEERKRTKKKKEQGQERTEEEML 251
++L+ ++ ++ + +++E +R +++EQ ++ TE+E L
Sbjct: 1694 REEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQL 1740
Score = 28.9 bits (63), Expect = 4.7
Identities = 21/104 (20%), Positives = 48/104 (46%), Gaps = 1/104 (0%)
Query: 154 KQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVSTEK 213
+Q +R+ P + R+ EE + ++K+ +E +L + + K+ +E E+
Sbjct: 114 RQEEDQRRFEPRD-RQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEE 172
Query: 214 LKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEEEMLWDQSIL 257
L ++++ + EE + K + +E +EE L + +L
Sbjct: 173 LWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELL 216
Score = 28.5 bits (62), Expect = 6.1
Identities = 21/104 (20%), Positives = 50/104 (48%), Gaps = 6/104 (5%)
Query: 150 QASHKQIHQKRKRHPE----EGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIE 205
+ +H+Q ++ +R + EKSE R + + E + ++ +R++ E
Sbjct: 752 ERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRF- 810
Query: 206 TVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEEE 249
+ EK + R++++ R+ + E + +++E+ Q+ EEE
Sbjct: 811 -LPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEE 853
>gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens]
Length = 237
Score = 47.4 bits (111), Expect = 1e-05
Identities = 30/103 (29%), Positives = 53/103 (51%), Gaps = 4/103 (3%)
Query: 139 HFSSDNSTSTHQASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRK 198
H SS++S S ++ K +K+K+ ++G EK ++ + K++K E DK S +
Sbjct: 130 HKSSESSMSETESDSKDSLKKKKKS-KDGTEKEKDIKGLSKKRKMYSE---DKPLSSESL 185
Query: 199 KTEVEIETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQ 241
IE V +K +EK + KK+ +K +KKKK++
Sbjct: 186 SESEYIEEVRAKKKKSSEEREKATEKTKKKKKHKKHSKKKKKK 228
Score = 42.0 bits (97), Expect = 5e-04
Identities = 28/95 (29%), Positives = 47/95 (49%), Gaps = 4/95 (4%)
Query: 147 STHQASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIET 206
S ++S K+ +K+K + GR S S S + D DK + +RKK +
Sbjct: 72 SGSESSSKKRQRKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKK---NR 128
Query: 207 VHVSTEKLKNRKEKKSRDVVSKKEERK-RTKKKKE 240
H S+E + E S+D + KK++ K T+K+K+
Sbjct: 129 SHKSSESSMSETESDSKDSLKKKKKSKDGTEKEKD 163
Score = 35.0 bits (79), Expect = 0.065
Identities = 30/127 (23%), Positives = 57/127 (44%), Gaps = 18/127 (14%)
Query: 141 SSDNSTSTHQASHKQIHQKRKRHPEEGRE-----------KSEEERSKHKRKKSCEEIDL 189
SSD+S+S+ + + Q ++R ++ R +S+ + S K+KKS + +
Sbjct: 101 SSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMSETESDSKDSLKKKKKSKDGTEK 160
Query: 190 DKHKSIQRKKTEVEIETVHVSTEKLKN-------RKEKKSRDVVSKKEERKRTKKKKEQG 242
+K KK ++ E +S+E L R +KK +K K KKKK +
Sbjct: 161 EKDIKGLSKKRKMYSEDKPLSSESLSESEYIEEVRAKKKKSSEEREKATEKTKKKKKHKK 220
Query: 243 QERTEEE 249
+ +++
Sbjct: 221 HSKKKKK 227
Score = 34.7 bits (78), Expect = 0.085
Identities = 33/117 (28%), Positives = 56/117 (47%), Gaps = 13/117 (11%)
Query: 137 YKHFSSDNSTSTHQASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQ 196
Y SS +S S+ +S + K++ R K ++ RS + S E + D S++
Sbjct: 94 YSSSSSSSSDSSSSSSDSEDEDKKQGK----RRKKKKNRSHKSSESSMSETESDSKDSLK 149
Query: 197 RKK-----TEVEIETVHVSTEKLKNRKEKK-SRDVVSKKE--ERKRTKKKKEQGQER 245
+KK TE E + +S ++ ++K S + +S+ E E R KKKK +ER
Sbjct: 150 KKKKSKDGTEKEKDIKGLSKKRKMYSEDKPLSSESLSESEYIEEVRAKKKK-SSEER 205
Score = 32.3 bits (72), Expect = 0.42
Identities = 28/110 (25%), Positives = 48/110 (43%), Gaps = 9/110 (8%)
Query: 148 THQASHKQIHQKRK------RHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTE 201
T + +Q+ +K+K E+ E ++E KH+ K K + QRKK E
Sbjct: 30 TWEEVKEQLEKKKKGSKALAEFEEKMNENWKKELEKHREKLLSGSESSSKKR--QRKKKE 87
Query: 202 VEIETVHVSTEKLKNRKEKKSRDVVSK-KEERKRTKKKKEQGQERTEEEM 250
+ + S+ + S D + K++ KR KKKK + + +E M
Sbjct: 88 KKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSM 137
>gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens]
Length = 247
Score = 47.4 bits (111), Expect = 1e-05
Identities = 30/103 (29%), Positives = 53/103 (51%), Gaps = 4/103 (3%)
Query: 139 HFSSDNSTSTHQASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRK 198
H SS++S S ++ K +K+K+ ++G EK ++ + K++K E DK S +
Sbjct: 140 HKSSESSMSETESDSKDSLKKKKKS-KDGTEKEKDIKGLSKKRKMYSE---DKPLSSESL 195
Query: 199 KTEVEIETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQ 241
IE V +K +EK + KK+ +K +KKKK++
Sbjct: 196 SESEYIEEVRAKKKKSSEEREKATEKTKKKKKHKKHSKKKKKK 238
Score = 42.0 bits (97), Expect = 5e-04
Identities = 28/95 (29%), Positives = 47/95 (49%), Gaps = 4/95 (4%)
Query: 147 STHQASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIET 206
S ++S K+ +K+K + GR S S S + D DK + +RKK +
Sbjct: 82 SGSESSSKKRQRKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKK---NR 138
Query: 207 VHVSTEKLKNRKEKKSRDVVSKKEERK-RTKKKKE 240
H S+E + E S+D + KK++ K T+K+K+
Sbjct: 139 SHKSSESSMSETESDSKDSLKKKKKSKDGTEKEKD 173
Score = 35.0 bits (79), Expect = 0.065
Identities = 30/127 (23%), Positives = 57/127 (44%), Gaps = 18/127 (14%)
Query: 141 SSDNSTSTHQASHKQIHQKRKRHPEEGRE-----------KSEEERSKHKRKKSCEEIDL 189
SSD+S+S+ + + Q ++R ++ R +S+ + S K+KKS + +
Sbjct: 111 SSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMSETESDSKDSLKKKKKSKDGTEK 170
Query: 190 DKHKSIQRKKTEVEIETVHVSTEKLKN-------RKEKKSRDVVSKKEERKRTKKKKEQG 242
+K KK ++ E +S+E L R +KK +K K KKKK +
Sbjct: 171 EKDIKGLSKKRKMYSEDKPLSSESLSESEYIEEVRAKKKKSSEEREKATEKTKKKKKHKK 230
Query: 243 QERTEEE 249
+ +++
Sbjct: 231 HSKKKKK 237
Score = 34.7 bits (78), Expect = 0.085
Identities = 33/117 (28%), Positives = 56/117 (47%), Gaps = 13/117 (11%)
Query: 137 YKHFSSDNSTSTHQASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQ 196
Y SS +S S+ +S + K++ R K ++ RS + S E + D S++
Sbjct: 104 YSSSSSSSSDSSSSSSDSEDEDKKQGK----RRKKKKNRSHKSSESSMSETESDSKDSLK 159
Query: 197 RKK-----TEVEIETVHVSTEKLKNRKEKK-SRDVVSKKE--ERKRTKKKKEQGQER 245
+KK TE E + +S ++ ++K S + +S+ E E R KKKK +ER
Sbjct: 160 KKKKSKDGTEKEKDIKGLSKKRKMYSEDKPLSSESLSESEYIEEVRAKKKK-SSEER 215
Score = 32.3 bits (72), Expect = 0.42
Identities = 28/110 (25%), Positives = 48/110 (43%), Gaps = 9/110 (8%)
Query: 148 THQASHKQIHQKRK------RHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTE 201
T + +Q+ +K+K E+ E ++E KH+ K K + QRKK E
Sbjct: 40 TWEEVKEQLEKKKKGSKALAEFEEKMNENWKKELEKHREKLLSGSESSSKKR--QRKKKE 97
Query: 202 VEIETVHVSTEKLKNRKEKKSRDVVSK-KEERKRTKKKKEQGQERTEEEM 250
+ + S+ + S D + K++ KR KKKK + + +E M
Sbjct: 98 KKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSM 147
>gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo
sapiens]
Length = 956
Score = 47.0 bits (110), Expect = 2e-05
Identities = 61/234 (26%), Positives = 107/234 (45%), Gaps = 20/234 (8%)
Query: 29 PKTCFRKMKGDYLETCG--YKGEVNSRPTYRMFDQRLPS-ETIQTYPRSCNIPQTVENRL 85
P+ C RK + + E G +KG+V + R P +++ P+ N+ T E+ +
Sbjct: 214 PRMCPRKEQDSWSEAGGILFKGKVPMVVLQDILAVRPPQIKSLPATPQGKNM--TPESEV 271
Query: 86 PQWLPAHDSRLRLDSLSYCQFTRDCFSEKPVPLNFNQQEYICGSHGVEHRVYKHF---SS 142
+ P DS L SLS T P + S + R+ K F S+
Sbjct: 272 LESFPEEDSVLSHSSLSSPSSTSSPEGPPAPPKQHSSTSPFPTSTPLR-RITKKFVKGST 330
Query: 143 DNSTSTHQASHKQIHQKRKRHPE-EGREKSEEERSKHK---RKKSCEEIDL-DKHKSIQR 197
+ + Q +++ ++ K E E +EK +EE + K +KK EE +L +K + +R
Sbjct: 331 EKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKR 390
Query: 198 KKTEVEIETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEEEML 251
+K E E ++LK + K+ ++ + K E KR KK+E+ + R EE+ +
Sbjct: 391 EKDEKE----KAEKQRLKEERRKERQEALEAKLEEKR--KKEEEKRLREEEKRI 438
Score = 38.9 bits (89), Expect = 0.005
Identities = 26/88 (29%), Positives = 45/88 (51%), Gaps = 8/88 (9%)
Query: 154 KQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVSTEK 213
K+ ++ K+ EE +E E+ER + + K E+ + + K +RK+ + +E EK
Sbjct: 365 KRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEKQRLKEERRKERQEALEA--KLEEK 422
Query: 214 LKNRKEKKSRDVVSKKEERKRTKKKKEQ 241
K +EK+ R EE KR K +K +
Sbjct: 423 RKKEEEKRLR------EEEKRIKAEKAE 444
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 46.6 bits (109), Expect = 2e-05
Identities = 24/101 (23%), Positives = 55/101 (54%), Gaps = 3/101 (2%)
Query: 154 KQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVSTEK 213
K+ ++ K+ ++ + EEER + + KK EE ++ + Q +K + + E + EK
Sbjct: 540 KKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMRE---QEEKMQEQEEKMREQEEK 596
Query: 214 LKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEEEMLWDQ 254
+ ++EK E+ ++ +++E+ + + +EEM+W+Q
Sbjct: 597 MWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQ 637
Score = 43.5 bits (101), Expect = 2e-04
Identities = 29/111 (26%), Positives = 58/111 (52%), Gaps = 6/111 (5%)
Query: 150 QASHKQIHQKRKRHPEEGR--EKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETV 207
+ K Q++K +E R E+ E R K +R + +++ + K + KKT+ + +
Sbjct: 490 EQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKT 549
Query: 208 HVSTEKLKNRKEKKSRD-VVSKKEERKRTKKKKEQGQE---RTEEEMLWDQ 254
EK++ + + R+ + ++EE R +++K Q QE R +EE +W+Q
Sbjct: 550 WDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQ 600
Score = 42.4 bits (98), Expect = 4e-04
Identities = 30/123 (24%), Positives = 60/123 (48%), Gaps = 18/123 (14%)
Query: 150 QASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSI------QRKKTEVE 203
+ K Q+ K +E + + +EE+ + +K E+ + DK + Q +K + +
Sbjct: 585 EQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQ 644
Query: 204 IETVHVSTEKLKNRKEK--KSRDVVSKKEERKRTKKKKEQGQE----------RTEEEML 251
E + EK++ ++EK + + + +EE+ R +++K QGQE R +EE +
Sbjct: 645 EEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKM 704
Query: 252 WDQ 254
W Q
Sbjct: 705 WGQ 707
Score = 42.0 bits (97), Expect = 5e-04
Identities = 28/109 (25%), Positives = 61/109 (55%), Gaps = 8/109 (7%)
Query: 154 KQIHQKRKRHPEEGREKSEEERSKHKRKKSCE---EIDLDKHKSIQRKKTEVEIETVHVS 210
K Q+ + +EG+ + +EE+ + + K+ E E+ + + ++KK + E +
Sbjct: 256 KMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQ 315
Query: 211 TEKLKNRKEK--KSRDVVSKKEER--KRTKKKKEQGQE-RTEEEMLWDQ 254
EK+ ++EK + + + ++EER ++ K+ +EQ Q+ R +EE +W+Q
Sbjct: 316 EEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQ 364
Score = 38.1 bits (87), Expect = 0.008
Identities = 23/93 (24%), Positives = 48/93 (51%), Gaps = 3/93 (3%)
Query: 165 EEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVSTEKLKNRKEKKSRD 224
E REK E R + K + E++ ++ + KK E ET+ EK++ ++E
Sbjct: 366 ERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQ 425
Query: 225 VVSKKEERKRTKKKK---EQGQERTEEEMLWDQ 254
+ ++++ ++K+ EQ + + +EE +W+Q
Sbjct: 426 EEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQ 458
Score = 36.6 bits (83), Expect = 0.022
Identities = 24/105 (22%), Positives = 55/105 (52%), Gaps = 8/105 (7%)
Query: 150 QASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHV 209
Q + ++ R EE RE+ ++ R + ++ EE ++ ++ ++ ++ +
Sbjct: 226 QVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQ---- 281
Query: 210 STEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEEEMLWDQ 254
EK +EK+ R+ + E+K+ ++++EQ QE +EE +W+Q
Sbjct: 282 --EKRLREQEKELREQEKELREQKKLREQEEQMQE--QEEKMWEQ 322
Score = 35.8 bits (81), Expect = 0.038
Identities = 24/104 (23%), Positives = 53/104 (50%), Gaps = 7/104 (6%)
Query: 154 KQIHQKRKRHPEEGREKSEEERSKHKRKKSC---EEIDLDKHKSIQRKKTEVEIETVHVS 210
++I ++ K+ EE E+E K++++ EE + + + ++K+ E E +
Sbjct: 392 ERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQ 451
Query: 211 TEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEEEMLWDQ 254
EK+ ++EK + ++E + KK Q + R +E+ +W+Q
Sbjct: 452 EEKIWEQEEK----IRDQEEMWGQEKKMWRQEKMREQEDQMWEQ 491
Score = 35.0 bits (79), Expect = 0.065
Identities = 24/100 (24%), Positives = 52/100 (52%), Gaps = 5/100 (5%)
Query: 158 QKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVSTEKLKNR 217
Q++K +E + +EER + + K E+ + K + +++ E E E E + +
Sbjct: 246 QEKKIRKQEEKMWRQEERLREQEGKMREQEE--KMRRQEKRLREQEKELREQEKELREQK 303
Query: 218 KEKKSRDVVSKKEERKRTKKKKEQGQERT---EEEMLWDQ 254
K ++ + + ++EE+ +++K + QE +EE LW+Q
Sbjct: 304 KLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQ 343
Score = 34.7 bits (78), Expect = 0.085
Identities = 24/115 (20%), Positives = 55/115 (47%), Gaps = 13/115 (11%)
Query: 150 QASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHV 209
+ K Q+ K +E + +EER + K+ E+ ++ Q ++ + E +
Sbjct: 314 EQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQ---EQKMRDQEERMWEQDERLRE 370
Query: 210 STEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERT----------EEEMLWDQ 254
E+++ +++ ++ ++EER R ++KK + +E T +EE +W+Q
Sbjct: 371 KEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQ 425
Score = 34.3 bits (77), Expect = 0.11
Identities = 20/90 (22%), Positives = 48/90 (53%), Gaps = 2/90 (2%)
Query: 168 REKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVSTEKLKNRKEKKSRDVVS 227
RE+ ++ R + +R +E +K + ++ ++ E E E+++ R++K + +
Sbjct: 348 REQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEET 407
Query: 228 KKEERKRTKKKKEQGQERTEEEMLWDQSIL 257
+E+ ++ +K++E E+ E+E W Q L
Sbjct: 408 MREQEEKMQKQEENMWEQEEKE--WQQQRL 435
Score = 34.3 bits (77), Expect = 0.11
Identities = 30/110 (27%), Positives = 53/110 (48%), Gaps = 13/110 (11%)
Query: 154 KQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVSTEK 213
K Q++ R E+ + EE+ ++K +E + + R+K E E + ++
Sbjct: 474 KMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQE 533
Query: 214 LKNRKEKKSRDVVSK---------KEERKRTKKKKEQGQERTEEEMLWDQ 254
K R+EKK+++ K +EER R ++KK R EEEM+ +Q
Sbjct: 534 EKMREEKKTQEQEKKTWDQEEKMREEERMREREKK----MREEEEMMREQ 579
Score = 33.9 bits (76), Expect = 0.15
Identities = 22/103 (21%), Positives = 54/103 (52%), Gaps = 10/103 (9%)
Query: 154 KQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVSTEK 213
K++ ++ K E+ + + +EE+ + + +K E+ + + + + + E + EK
Sbjct: 290 KELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLW----EQEK 345
Query: 214 LKNRKEKKSRDVVSKKEER--KRTKKKKEQGQERTEEEMLWDQ 254
+E+K RD +EER ++ ++ +E+ + E+E +W+Q
Sbjct: 346 QMREQEQKMRD----QEERMWEQDERLREKEERMREQEKMWEQ 384
Score = 32.3 bits (72), Expect = 0.42
Identities = 24/105 (22%), Positives = 49/105 (46%), Gaps = 9/105 (8%)
Query: 150 QASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHV 209
+ K Q+ K +E + + +EE+ + + +K E+ ++ Q +K + E +
Sbjct: 643 EQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQ---EEKMQGQEEKMREQEEKMRG 699
Query: 210 STEKLKNRKEK------KSRDVVSKKEERKRTKKKKEQGQERTEE 248
EK+ ++EK K +E+ +R + +KE+ QER E
Sbjct: 700 QEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPE 744
Score = 32.0 bits (71), Expect = 0.55
Identities = 30/107 (28%), Positives = 55/107 (51%), Gaps = 10/107 (9%)
Query: 158 QKRKRHPE---EGREKS-EEERSKHKRKKSCEEIDLDKHKSIQRKKTEV---EIETVHVS 210
++R R E E EK EEER + + KK EE + + + + +K E E E
Sbjct: 372 EERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQ 431
Query: 211 TEKLKNRKEKK-SRDVVSKKEERKRTKKKKEQGQERT--EEEMLWDQ 254
++L +KEK ++ + ++EE+ +++K + QE +E+ +W Q
Sbjct: 432 QQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQ 478
Score = 29.6 bits (65), Expect = 2.7
Identities = 24/99 (24%), Positives = 48/99 (48%), Gaps = 7/99 (7%)
Query: 158 QKRKRHPEE--GREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVSTEKLK 215
+++ R EE G+EK + K + ++ +K + ++K + E E + E+L+
Sbjct: 459 EEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQE-ERMWEQDERLR 517
Query: 216 NRKEKKSRDVVSKKEERKRTKKKKEQGQERTEEEMLWDQ 254
++E+ ++E K ++KK Q QE+ WDQ
Sbjct: 518 EKEERMREQKKMWQQEEKMREEKKTQEQEK----KTWDQ 552
Score = 29.3 bits (64), Expect = 3.6
Identities = 21/98 (21%), Positives = 51/98 (52%), Gaps = 4/98 (4%)
Query: 158 QKRKRHPEEGREKSEEERSKHKRK-KSCEEIDLDKHKSIQRKKTEVEIETVHVSTEKLKN 216
QK K +E ++ EE+ + + K + EE+ + K +++K + + + EK+++
Sbjct: 438 QKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRD 497
Query: 217 RKEKKSRDVVSKKEERKRTKKKKEQGQERTEEEMLWDQ 254
+++K E+ +R ++K+E+ E++ +W Q
Sbjct: 498 QEQKMWDQEERMWEQDERLREKEER---MREQKKMWQQ 532
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 46.2 bits (108), Expect = 3e-05
Identities = 27/105 (25%), Positives = 51/105 (48%), Gaps = 12/105 (11%)
Query: 145 STSTHQASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEI 204
S S H+ K +++ R R+K ++ R K K K+ +E D +K + ++++
Sbjct: 351 SKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKER----- 405
Query: 205 ETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEEE 249
EK K R + K RD +K+ K +K +E+ +E+ E+
Sbjct: 406 -------EKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEK 443
Score = 43.1 bits (100), Expect = 2e-04
Identities = 26/111 (23%), Positives = 55/111 (49%), Gaps = 10/111 (9%)
Query: 138 KHFSSDNSTSTHQASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQR 197
K S +S + + ++I +K + ++ ++ E E+ + K K+ + D DK + R
Sbjct: 366 KSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDR 425
Query: 198 KKTEVEIETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEE 248
+K + EK + R+ +K + KE+ K K+KE+ ++R++E
Sbjct: 426 EKDK----------EKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKE 466
Score = 41.6 bits (96), Expect = 7e-04
Identities = 27/125 (21%), Positives = 54/125 (43%), Gaps = 3/125 (2%)
Query: 128 GSHGVEHRVYKHFSSDNSTSTH---QASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSC 184
G H K SS S S Q+ H+ R R ++ R +S+ K + +
Sbjct: 305 GGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRER 364
Query: 185 EEIDLDKHKSIQRKKTEVEIETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQE 244
+ H +RK T +I+ EK + ++ ++ ++ +KE K + KE+ ++
Sbjct: 365 RKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKD 424
Query: 245 RTEEE 249
R +++
Sbjct: 425 REKDK 429
Score = 41.2 bits (95), Expect = 0.001
Identities = 29/94 (30%), Positives = 49/94 (52%), Gaps = 2/94 (2%)
Query: 154 KQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVSTEK 213
K+ ++++R E+ REK E+ER K+K + E D +K K R++ + EK
Sbjct: 391 KEKDREKEREREKEREK-EKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEK 449
Query: 214 LKNRKEKKSRDVVSKKE-ERKRTKKKKEQGQERT 246
K + ++K R+ KE + KR K KK + R+
Sbjct: 450 EKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRS 483
Score = 40.0 bits (92), Expect = 0.002
Identities = 31/115 (26%), Positives = 51/115 (44%), Gaps = 12/115 (10%)
Query: 141 SSDNSTSTHQASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKT 200
S S S +++ +Q ++R + P + R KS E R R S DK K + K
Sbjct: 331 SKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHS-----RDKRKDTREKIK 385
Query: 201 EVEIETVHVSTEKLKNRKEKKSRDVV------SKKEERKRTKKKKEQGQERTEEE 249
E E EK + R++++ ++ KE K +K KE+ +ER E+
Sbjct: 386 EKE-RVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREK 439
Score = 38.5 bits (88), Expect = 0.006
Identities = 26/123 (21%), Positives = 51/123 (41%), Gaps = 13/123 (10%)
Query: 138 KHFSSDNSTSTHQASHKQIHQKRKRHPEE---------GREKSEEERSKHKRKKSCEEID 188
K D + K+I +KRK+ + R R + +R+
Sbjct: 449 KEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRS 508
Query: 189 LDKHKSIQRKKTEVEIETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEE 248
K+I+RK + + + K++K +K RD +S++ ER+R+ ++ +R +
Sbjct: 509 PRTSKTIKRKSSR----SPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGK 564
Query: 249 EML 251
E L
Sbjct: 565 EKL 567
Score = 37.0 bits (84), Expect = 0.017
Identities = 25/108 (23%), Positives = 48/108 (44%), Gaps = 3/108 (2%)
Query: 145 STSTHQASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEI 204
S + S K +K R R KS H R+K + + + R + +
Sbjct: 290 SAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRR 349
Query: 205 ETVHVSTEKLKNRKEKKSRDVVSKKEERKRTK---KKKEQGQERTEEE 249
+ ++ K+R+ +KSR +++RK T+ K+KE+ +E+ E+
Sbjct: 350 RSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREK 397
Score = 35.4 bits (80), Expect = 0.050
Identities = 25/89 (28%), Positives = 44/89 (49%), Gaps = 2/89 (2%)
Query: 157 HQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVSTEKLKN 216
++ R + E+ REK +E+ + +R+K E+ D DK K ++ K E E E K
Sbjct: 414 NKDRDKEREKDREKDKEKDREREREKEHEK-DRDKEKEKEQDK-EKEREKDRSKEIDEKR 471
Query: 217 RKEKKSRDVVSKKEERKRTKKKKEQGQER 245
+K+KKSR +R++ + + R
Sbjct: 472 KKDKKSRTPPRSYNASRRSRSSSRERRRR 500
Score = 35.4 bits (80), Expect = 0.050
Identities = 26/119 (21%), Positives = 48/119 (40%), Gaps = 3/119 (2%)
Query: 129 SHGVEHRVYKHFSSDNSTSTHQASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEID 188
S ++ + K S ++ AS + R+R R S R+ K+
Sbjct: 464 SKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSP 523
Query: 189 LDKHKSIQRKKTEVEIETVHVSTEKLKN---RKEKKSRDVVSKKEERKRTKKKKEQGQE 244
+ ++ + KK E E + + E+ ++ RK RD K E+ + K+KE +E
Sbjct: 524 SPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKE 582
Score = 33.5 bits (75), Expect = 0.19
Identities = 25/109 (22%), Positives = 46/109 (42%), Gaps = 16/109 (14%)
Query: 157 HQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDK----------------HKSIQRKKT 200
H+K + +E + E+ER K + K+ E+ DK S +R++
Sbjct: 441 HEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRR 500
Query: 201 EVEIETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEEE 249
+ T K RK +S S+ ++ K+ +K+++ ER E E
Sbjct: 501 RSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERE 549
Score = 30.0 bits (66), Expect = 2.1
Identities = 20/94 (21%), Positives = 45/94 (47%), Gaps = 4/94 (4%)
Query: 158 QKRKRHPEEGREKSEEERSKHKRKKSCE-EIDLDKHKSIQRKKTEVEIETVHVSTEKLKN 216
+++ R ++ +++ E +H++ + E E + DK K ++ +++ EI+ +K +
Sbjct: 421 REKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSK-EIDEKRKKDKKSRT 479
Query: 217 --RKEKKSRDVVSKKEERKRTKKKKEQGQERTEE 248
R SR S ER+R + + RT +
Sbjct: 480 PPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSK 513
Score = 28.1 bits (61), Expect = 8.0
Identities = 22/107 (20%), Positives = 43/107 (40%), Gaps = 6/107 (5%)
Query: 145 STSTHQASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEI 204
S+S + K I +K R P S R+K +K+ E + + + +R + +
Sbjct: 504 SSSRSPRTSKTIKRKSSRSP------SPRSRNKKDKKREKERDHISERRERERSTSMRKS 557
Query: 205 ETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEEEML 251
EKL+ +K+ + +K+ ++ RTEE +
Sbjct: 558 SNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENKI 604
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 46.2 bits (108), Expect = 3e-05
Identities = 27/105 (25%), Positives = 51/105 (48%), Gaps = 12/105 (11%)
Query: 145 STSTHQASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEI 204
S S H+ K +++ R R+K ++ R K K K+ +E D +K + ++++
Sbjct: 235 SKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKER----- 289
Query: 205 ETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEEE 249
EK K R + K RD +K+ K +K +E+ +E+ E+
Sbjct: 290 -------EKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEK 327
Score = 43.1 bits (100), Expect = 2e-04
Identities = 26/111 (23%), Positives = 55/111 (49%), Gaps = 10/111 (9%)
Query: 138 KHFSSDNSTSTHQASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQR 197
K S +S + + ++I +K + ++ ++ E E+ + K K+ + D DK + R
Sbjct: 250 KSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDR 309
Query: 198 KKTEVEIETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEE 248
+K + EK + R+ +K + KE+ K K+KE+ ++R++E
Sbjct: 310 EKDK----------EKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKE 350
Score = 41.6 bits (96), Expect = 7e-04
Identities = 27/125 (21%), Positives = 54/125 (43%), Gaps = 3/125 (2%)
Query: 128 GSHGVEHRVYKHFSSDNSTSTH---QASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSC 184
G H K SS S S Q+ H+ R R ++ R +S+ K + +
Sbjct: 189 GGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRER 248
Query: 185 EEIDLDKHKSIQRKKTEVEIETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQE 244
+ H +RK T +I+ EK + ++ ++ ++ +KE K + KE+ ++
Sbjct: 249 RKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKD 308
Query: 245 RTEEE 249
R +++
Sbjct: 309 REKDK 313
Score = 41.2 bits (95), Expect = 0.001
Identities = 29/94 (30%), Positives = 49/94 (52%), Gaps = 2/94 (2%)
Query: 154 KQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVSTEK 213
K+ ++++R E+ REK E+ER K+K + E D +K K R++ + EK
Sbjct: 275 KEKDREKEREREKEREK-EKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEK 333
Query: 214 LKNRKEKKSRDVVSKKE-ERKRTKKKKEQGQERT 246
K + ++K R+ KE + KR K KK + R+
Sbjct: 334 EKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRS 367
Score = 40.0 bits (92), Expect = 0.002
Identities = 31/115 (26%), Positives = 51/115 (44%), Gaps = 12/115 (10%)
Query: 141 SSDNSTSTHQASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKT 200
S S S +++ +Q ++R + P + R KS E R R S DK K + K
Sbjct: 215 SKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHS-----RDKRKDTREKIK 269
Query: 201 EVEIETVHVSTEKLKNRKEKKSRDVV------SKKEERKRTKKKKEQGQERTEEE 249
E E EK + R++++ ++ KE K +K KE+ +ER E+
Sbjct: 270 EKE-RVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREK 323
Score = 38.5 bits (88), Expect = 0.006
Identities = 26/123 (21%), Positives = 51/123 (41%), Gaps = 13/123 (10%)
Query: 138 KHFSSDNSTSTHQASHKQIHQKRKRHPEE---------GREKSEEERSKHKRKKSCEEID 188
K D + K+I +KRK+ + R R + +R+
Sbjct: 333 KEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRS 392
Query: 189 LDKHKSIQRKKTEVEIETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEE 248
K+I+RK + + + K++K +K RD +S++ ER+R+ ++ +R +
Sbjct: 393 PRTSKTIKRKSSR----SPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGK 448
Query: 249 EML 251
E L
Sbjct: 449 EKL 451
Score = 37.0 bits (84), Expect = 0.017
Identities = 25/108 (23%), Positives = 48/108 (44%), Gaps = 3/108 (2%)
Query: 145 STSTHQASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEI 204
S + S K +K R R KS H R+K + + + R + +
Sbjct: 174 SAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRR 233
Query: 205 ETVHVSTEKLKNRKEKKSRDVVSKKEERKRTK---KKKEQGQERTEEE 249
+ ++ K+R+ +KSR +++RK T+ K+KE+ +E+ E+
Sbjct: 234 RSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREK 281
Score = 35.4 bits (80), Expect = 0.050
Identities = 25/89 (28%), Positives = 44/89 (49%), Gaps = 2/89 (2%)
Query: 157 HQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVSTEKLKN 216
++ R + E+ REK +E+ + +R+K E+ D DK K ++ K E E E K
Sbjct: 298 NKDRDKEREKDREKDKEKDREREREKEHEK-DRDKEKEKEQDK-EKEREKDRSKEIDEKR 355
Query: 217 RKEKKSRDVVSKKEERKRTKKKKEQGQER 245
+K+KKSR +R++ + + R
Sbjct: 356 KKDKKSRTPPRSYNASRRSRSSSRERRRR 384
Score = 35.4 bits (80), Expect = 0.050
Identities = 26/119 (21%), Positives = 48/119 (40%), Gaps = 3/119 (2%)
Query: 129 SHGVEHRVYKHFSSDNSTSTHQASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEID 188
S ++ + K S ++ AS + R+R R S R+ K+
Sbjct: 348 SKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSP 407
Query: 189 LDKHKSIQRKKTEVEIETVHVSTEKLKN---RKEKKSRDVVSKKEERKRTKKKKEQGQE 244
+ ++ + KK E E + + E+ ++ RK RD K E+ + K+KE +E
Sbjct: 408 SPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKE 466
Score = 33.5 bits (75), Expect = 0.19
Identities = 25/109 (22%), Positives = 46/109 (42%), Gaps = 16/109 (14%)
Query: 157 HQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDK----------------HKSIQRKKT 200
H+K + +E + E+ER K + K+ E+ DK S +R++
Sbjct: 325 HEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRR 384
Query: 201 EVEIETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEEE 249
+ T K RK +S S+ ++ K+ +K+++ ER E E
Sbjct: 385 RSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERE 433
Score = 30.0 bits (66), Expect = 2.1
Identities = 20/94 (21%), Positives = 45/94 (47%), Gaps = 4/94 (4%)
Query: 158 QKRKRHPEEGREKSEEERSKHKRKKSCE-EIDLDKHKSIQRKKTEVEIETVHVSTEKLKN 216
+++ R ++ +++ E +H++ + E E + DK K ++ +++ EI+ +K +
Sbjct: 305 REKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSK-EIDEKRKKDKKSRT 363
Query: 217 --RKEKKSRDVVSKKEERKRTKKKKEQGQERTEE 248
R SR S ER+R + + RT +
Sbjct: 364 PPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSK 397
Score = 28.1 bits (61), Expect = 8.0
Identities = 22/107 (20%), Positives = 43/107 (40%), Gaps = 6/107 (5%)
Query: 145 STSTHQASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEI 204
S+S + K I +K R P S R+K +K+ E + + + +R + +
Sbjct: 388 SSSRSPRTSKTIKRKSSRSP------SPRSRNKKDKKREKERDHISERRERERSTSMRKS 441
Query: 205 ETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEEEML 251
EKL+ +K+ + +K+ ++ RTEE +
Sbjct: 442 SNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENKI 488
>gi|151301228 formin binding protein 3 [Homo sapiens]
Length = 930
Score = 46.2 bits (108), Expect = 3e-05
Identities = 29/119 (24%), Positives = 53/119 (44%), Gaps = 10/119 (8%)
Query: 130 HGVEHRVYKHFSSDNSTSTHQASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDL 189
H +EH H S + H K+ H+KR R ++ SK KR++S
Sbjct: 771 HVLEHECQHHHSKNKK---HSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKRQRS------ 821
Query: 190 DKHKSIQRKKTEVEIETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEE 248
+ +S + E E + ++K K + +K+ S + + +R K KKE+ +E ++
Sbjct: 822 -ESRSASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDAEREKDKKEKDRESEKD 879
Score = 33.5 bits (75), Expect = 0.19
Identities = 24/101 (23%), Positives = 49/101 (48%), Gaps = 1/101 (0%)
Query: 141 SSDNSTSTHQASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKT 200
+S++S+S + +K K+ ++ R KS+ S +R+K +E D + K R+++
Sbjct: 826 ASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDAEREKDKKEKDRESEKDRTRQRS 885
Query: 201 EVEIETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQ 241
E + ++ T K + + +S+ E KR + EQ
Sbjct: 886 ESKHKSPKKKTGKDSGNWDTSGSE-LSEGELEKRRRTLLEQ 925
>gi|11225260 DNA topoisomerase I [Homo sapiens]
Length = 765
Score = 45.8 bits (107), Expect = 4e-05
Identities = 29/96 (30%), Positives = 47/96 (48%), Gaps = 16/96 (16%)
Query: 153 HKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVSTE 212
HK H+ R+ +E +++ + E+SKH + HK ++K E E +T H
Sbjct: 24 HKDKHKDREHRHKEHKKEKDREKSKHSNSE---------HKDSEKKHKEKE-KTKHKDGS 73
Query: 213 KLKNRKEKKSRDVVSKKEERKRT------KKKKEQG 242
K++ + K RD +KEE+ R KK+KE G
Sbjct: 74 SEKHKDKHKDRDKEKRKEEKVRASGDAKIKKEKENG 109
Score = 32.7 bits (73), Expect = 0.32
Identities = 25/89 (28%), Positives = 44/89 (49%), Gaps = 17/89 (19%)
Query: 163 HPEEGREKSEEERSK-HKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVSTEKLKNRKEKK 221
H + + K E R K HK++K E+ KH + + K +E +K K +++ K
Sbjct: 22 HKHKDKHKDREHRHKEHKKEKDREK---SKHSNSEHKDSE----------KKHKEKEKTK 68
Query: 222 SRDVVSKKEERKRTKKKKEQGQERTEEEM 250
+D S+K + K + KE +R EE++
Sbjct: 69 HKDGSSEKHKDKHKDRDKE---KRKEEKV 94
Score = 31.2 bits (69), Expect = 0.94
Identities = 37/140 (26%), Positives = 55/140 (39%), Gaps = 34/140 (24%)
Query: 143 DNSTSTHQASHKQIHQKRKRHPEEGREKSEEERSKHKR---------------------- 180
D S+ H+ HK K KR E+ R + + K K
Sbjct: 71 DGSSEKHKDKHKD-RDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPP 129
Query: 181 -------KKSCEEIDLD-KHKSIQRKKTEVEIETVHVSTE--KLKNRKEK-KSRDVVSKK 229
K+ +E D D K K I+ + T+ E + E KLK K K K + V
Sbjct: 130 KEDIKPLKRPRDEDDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDKDKKVPEPD 189
Query: 230 EERKRTKKKKEQGQERTEEE 249
++K+ KK++EQ + EEE
Sbjct: 190 NKKKKPKKEEEQKWKWWEEE 209
Score = 28.9 bits (63), Expect = 4.7
Identities = 18/72 (25%), Positives = 34/72 (47%)
Query: 178 HKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKK 237
H S E D + S + K + E H +K K+R++ K + K E+K +K
Sbjct: 5 HLHNDSQIEADFRLNDSHKHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEK 64
Query: 238 KKEQGQERTEEE 249
+K + ++ + E+
Sbjct: 65 EKTKHKDGSSEK 76
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 45.8 bits (107), Expect = 4e-05
Identities = 32/95 (33%), Positives = 54/95 (56%), Gaps = 6/95 (6%)
Query: 150 QASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHV 209
Q S ++I + R+R E REK E+ + +R+K E+ D+ + Q K+ E+E E
Sbjct: 498 QPSPEEIRE-REREKEREREKELEKEQEQEREKEREK---DRERQ-QEKEKELEKEQ-EK 551
Query: 210 STEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQE 244
E K RK++K +++ +KE+ K +K KEQ +E
Sbjct: 552 QREMEKERKQEKEKELERQKEKEKELQKMKEQEKE 586
Score = 37.4 bits (85), Expect = 0.013
Identities = 27/118 (22%), Positives = 57/118 (48%), Gaps = 21/118 (17%)
Query: 151 ASHKQIHQKRKRHPEE---------GREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTE 201
A +I ++R+R E R + EE R + +RK +C E ++R +
Sbjct: 439 ADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAE-------KLKRLDEK 491
Query: 202 VEIETVHVSTEKLKNRKEKKSRD-----VVSKKEERKRTKKKKEQGQERTEEEMLWDQ 254
+ I S E+++ R+ +K R+ +++ER++ ++K + Q+ E+E+ +Q
Sbjct: 492 LGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQ 549
Score = 36.2 bits (82), Expect = 0.029
Identities = 30/115 (26%), Positives = 53/115 (46%), Gaps = 15/115 (13%)
Query: 150 QASHKQIHQKRKRHPEEGRE---KSEEERSKHKRKKSCEEIDL----DKHKSIQRKK--- 199
Q K+ + R+R E+ +E + E++R K +K +E +L +K K +Q+ K
Sbjct: 525 QEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQE 584
Query: 200 TEVEIETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKE-----QGQERTEEE 249
E E+E E+ +E +V K+E K++E Q R+E+E
Sbjct: 585 KECELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKE 639
Score = 34.7 bits (78), Expect = 0.085
Identities = 22/97 (22%), Positives = 48/97 (49%), Gaps = 2/97 (2%)
Query: 156 IHQKRKRHPEEGREKSEEERSK--HKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVSTEK 213
+ + RKR EE R E+ ++ K K+ E++ + + + + E E E ++
Sbjct: 459 VERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKE 518
Query: 214 LKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEEEM 250
L+ +E++ K ER++ K+K+ + ++ + EM
Sbjct: 519 LEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREM 555
Score = 34.7 bits (78), Expect = 0.085
Identities = 27/122 (22%), Positives = 56/122 (45%), Gaps = 12/122 (9%)
Query: 133 EHRVYKHFSSDNSTSTHQASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKH 192
E + K + + K+ Q++++ E +EK +E + +++K CE L+K
Sbjct: 536 ERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECE---LEK- 591
Query: 193 KSIQRKKTEVEIETVHVSTEKLKNRKE-----KKSRDVVSKKEERKRTKKKKEQGQERTE 247
+R+K E +IE + E + ++E K + V +++ R++K+ TE
Sbjct: 592 ---EREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEATPVVHETE 648
Query: 248 EE 249
E
Sbjct: 649 PE 650
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 45.4 bits (106), Expect = 5e-05
Identities = 28/115 (24%), Positives = 58/115 (50%), Gaps = 9/115 (7%)
Query: 138 KHFSSDNSTSTHQASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEE---IDLDKHKS 194
+H S H ++ H++RKRH EE ++K+ E + KR++ E + D+ +
Sbjct: 110 RHHSHSAEGGKHARVKEREHERRKRHREE-QDKARREWERQKRREMAREHSRRERDRLEQ 168
Query: 195 IQRKKTEVEIETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEEE 249
++RK+ E E+ K ++E+K R+ +++ ++R +++ RT E
Sbjct: 169 LERKR-----ERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMRE 218
Score = 37.7 bits (86), Expect = 0.010
Identities = 29/109 (26%), Positives = 53/109 (48%), Gaps = 14/109 (12%)
Query: 147 STHQASHKQIHQKRK---RH----PEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKK 199
S + H + +KRK RH E G+ +ER +RK+ EE D + + ++K+
Sbjct: 92 SRKEKVHHRKDEKRKEKCRHHSHSAEGGKHARVKEREHERRKRHREEQDKARREWERQKR 151
Query: 200 TEVEIETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEE 248
E+ E ++L+ + K+ R ERK +++KEQ +++ E
Sbjct: 152 REMAREHSRRERDRLEQLERKRER-------ERKMREQQKEQREQKERE 193
Score = 30.4 bits (67), Expect = 1.6
Identities = 24/116 (20%), Positives = 52/116 (44%), Gaps = 9/116 (7%)
Query: 134 HRVYKHFSSDNSTSTHQASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHK 193
HR + SD ++H + + + +GR+ +EE+ + + S DL
Sbjct: 213 HRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLS----DLQDIS 268
Query: 194 SIQRKKTEVEIETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEEE 249
+RK + E S+ + + E++ + ++EE +++ +E+ +E EEE
Sbjct: 269 DSERKTSSAES-----SSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEE 319
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 45.4 bits (106), Expect = 5e-05
Identities = 29/95 (30%), Positives = 48/95 (50%), Gaps = 4/95 (4%)
Query: 154 KQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVSTEK 213
+Q +R R E REK+ +ER + +R++ E D+H R++ E E ET TE
Sbjct: 167 RQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRER-ERERET---ETET 222
Query: 214 LKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEE 248
+ R+ + RD K E + + ++E+ ER E
Sbjct: 223 ERKRQTDRERDRQRKTEREREKQAERERASERETE 257
Score = 42.4 bits (98), Expect = 4e-04
Identities = 28/130 (21%), Positives = 60/130 (46%), Gaps = 13/130 (10%)
Query: 133 EHRVYKHFSSDNSTSTHQASHKQIHQKRKRHPEEGREK-------SEEERSKHKRKKSCE 185
+ R + ++ + ++ + RKR E RE+ +E +R K + +K
Sbjct: 288 QRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKR 347
Query: 186 EIDLDKHKSIQ-----RKKTEVEIETVHVSTEKLKNRKEKKSRD-VVSKKEERKRTKKKK 239
+ ++D+ ++ Q R++ E E E + +E++ RD +++ER+R +K
Sbjct: 348 QTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKD 407
Query: 240 EQGQERTEEE 249
GQ TE++
Sbjct: 408 RDGQRETEKQ 417
Score = 41.6 bits (96), Expect = 7e-04
Identities = 23/91 (25%), Positives = 44/91 (48%), Gaps = 3/91 (3%)
Query: 162 RHPEEGREKSEE---ERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVSTEKLKNRK 218
RH E GRE+ E E +++++ E D + +R+K TE+ K R+
Sbjct: 204 RHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERE 263
Query: 219 EKKSRDVVSKKEERKRTKKKKEQGQERTEEE 249
++ RD + +++R ++ + Q RTE +
Sbjct: 264 RERDRDRDRDRRQKERERQTDRKRQRRTERD 294
Score = 40.4 bits (93), Expect = 0.002
Identities = 22/106 (20%), Positives = 52/106 (49%), Gaps = 4/106 (3%)
Query: 143 DNSTSTHQASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEV 202
D + K+ ++ +R E GR++ + + + +R++ E+ ++ + R++
Sbjct: 114 DRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEK---ERERQTDRERQRQ 170
Query: 203 EIETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEE 248
E+ KNR+E++ R+ +++E K + E+G+ER E
Sbjct: 171 TERNRQKEREREKNRQERRERE-RQREKENKTEDRHSERGRERERE 215
Score = 40.0 bits (92), Expect = 0.002
Identities = 36/138 (26%), Positives = 67/138 (48%), Gaps = 20/138 (14%)
Query: 113 EKPVPLNFNQQEYICGSHGVEHR-----VYKHFSSDNSTSTHQASHKQIHQKRKRHPEEG 167
E +PL+F+++ GS R +K D+ Q ++ +KR+ E
Sbjct: 19 EVTIPLDFSRRRP--GSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETD 76
Query: 168 REKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVSTEKLKNRKEKKSRDVVS 227
R K E R K + +K D+H+ QR + E E E T++ ++R+ +K R+
Sbjct: 77 R-KRERRREKDRHRKR------DRHRERQRDR-EKERER---QTDRERDRQREKERN--R 123
Query: 228 KKEERKRTKKKKEQGQER 245
+KE + T+++ E+G++R
Sbjct: 124 QKERERETEREGERGRDR 141
Score = 40.0 bits (92), Expect = 0.002
Identities = 26/115 (22%), Positives = 55/115 (47%), Gaps = 11/115 (9%)
Query: 143 DNSTSTHQASHKQIHQKRKRHPEEGREK-SEEERSKHKRKKSCEEIDLDKHKSIQRKKTE 201
+ T T + + R+R E REK +E ER+ + + +E + ++ + R + +
Sbjct: 217 ETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQ 276
Query: 202 VEIETVHVSTEKLKNRKEKKSRDVVSKKE-------ERKRTKKKKEQGQERTEEE 249
E E T++ + R+ ++ R+ K+E ER+R +K++ + + E E
Sbjct: 277 KERER---QTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERE 328
Score = 38.9 bits (89), Expect = 0.005
Identities = 29/124 (23%), Positives = 57/124 (45%), Gaps = 22/124 (17%)
Query: 143 DNSTSTHQASHKQIHQKRKRHPE-----------EGREKSEEERSKHK-------RKKSC 184
+ T + K+ +KRKR E EGR ++E ER + + R++
Sbjct: 328 ERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREE 387
Query: 185 EEIDLDKHKSIQRKKTEVEIETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQE 244
E D D+ + +R++ + TEK + R+ +D S++ + +++K++G+E
Sbjct: 388 RERDRDRDRQKERERQTEKDRDGQRETEKQRERE----KDRESERGRERGREREKQKGRE 443
Query: 245 RTEE 248
R E
Sbjct: 444 RDRE 447
Score = 38.5 bits (88), Expect = 0.006
Identities = 26/98 (26%), Positives = 52/98 (53%), Gaps = 7/98 (7%)
Query: 154 KQIHQKRKRHPEEGREKSEE-ERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIE-----TV 207
K H+KR RH E R++ +E ER + + E + ++ K +R +TE E E
Sbjct: 85 KDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERER-ETEREGERGRDRQT 143
Query: 208 HVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQER 245
E+ + R +K R+ + +E +++T++ +++ +ER
Sbjct: 144 DGQRERERQRDAEKERERQTDRERQRQTERNRQKERER 181
Score = 38.1 bits (87), Expect = 0.008
Identities = 27/137 (19%), Positives = 60/137 (43%), Gaps = 4/137 (2%)
Query: 112 SEKPVPLNFNQQEYICGSHGVEHRVYKHFSSDNSTSTHQASHKQIHQKRKRHPEEGREKS 171
++K VP +Q G+ VE + FS S + + Q K + RE++
Sbjct: 2 AKKIVPATADQ----LGTLWVEVTIPLDFSRRRPGSQESPRRRGLGQAHKDADGDDRERN 57
Query: 172 EEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVSTEKLKNRKEKKSRDVVSKKEE 231
++ + +R+K E + D+ + +R+K H ++ + ++ ++ D ++
Sbjct: 58 RQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQR 117
Query: 232 RKRTKKKKEQGQERTEE 248
K ++KE+ +E E
Sbjct: 118 EKERNRQKERERETERE 134
Score = 37.4 bits (85), Expect = 0.013
Identities = 22/107 (20%), Positives = 50/107 (46%), Gaps = 2/107 (1%)
Query: 142 SDNSTSTHQASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTE 201
S+ + + +RKR + RE+ + +++ +R+K E + ++ + K+ E
Sbjct: 206 SERGRERERERETETETERKRQTD--RERDRQRKTEREREKQAERERASERETERDKERE 263
Query: 202 VEIETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEE 248
E + + K R+ + R + E + T++K+E+ +ER E
Sbjct: 264 RERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERE 310
Score = 36.2 bits (82), Expect = 0.029
Identities = 21/96 (21%), Positives = 47/96 (48%), Gaps = 6/96 (6%)
Query: 154 KQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVSTEK 213
+Q +KR+R E RE +E +R + + ++ E + + + +R++ EK
Sbjct: 281 RQTDRKRQRRTERDRE-TERKRERQRERERERERNRKRERERERERERERQRETERDREK 339
Query: 214 LKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEEE 249
+ RK K+ ++ +R+R ++ +G+ + E E
Sbjct: 340 ERERKRKRQTEM-----DRERNRQTGREGRRQAERE 370
Score = 35.8 bits (81), Expect = 0.038
Identities = 19/94 (20%), Positives = 50/94 (53%), Gaps = 8/94 (8%)
Query: 152 SHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVST 211
+ ++ ++R+R + RE+ E ER + + ++ E +K + QR+ +
Sbjct: 367 AERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEK--------QR 418
Query: 212 EKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQER 245
E+ K+R+ ++ R+ ++E++K ++ +E+ +R
Sbjct: 419 EREKDRESERGRERGREREKQKGRERDRERQTDR 452
Score = 35.0 bits (79), Expect = 0.065
Identities = 20/98 (20%), Positives = 47/98 (47%), Gaps = 1/98 (1%)
Query: 152 SHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCE-EIDLDKHKSIQRKKTEVEIETVHVS 210
+ ++ +KR+R E+ R + + + +R + E E D+ + QR+K +
Sbjct: 71 TERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERE 130
Query: 211 TEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEE 248
TE+ R + D ++E ++ +K++E+ +R +
Sbjct: 131 TEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQ 168
Score = 34.3 bits (77), Expect = 0.11
Identities = 18/95 (18%), Positives = 45/95 (47%), Gaps = 10/95 (10%)
Query: 154 KQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVSTEK 213
++ +++ +R E REK + +H + E + + +RK+ T++
Sbjct: 181 REKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKR----------QTDR 230
Query: 214 LKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEE 248
++R+ K R+ + E + ++++ E+ +ER E
Sbjct: 231 ERDRQRKTEREREKQAERERASERETERDKERERE 265
Score = 34.3 bits (77), Expect = 0.11
Identities = 20/115 (17%), Positives = 51/115 (44%), Gaps = 4/115 (3%)
Query: 138 KHFSSDNSTSTHQASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQR 197
K + ++ K+ ++R R + R + E ER ++++ E D + + +R
Sbjct: 244 KQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRER 303
Query: 198 KKTEVEIETVHVSTEKLKNRKEKKSRDVVSK----KEERKRTKKKKEQGQERTEE 248
++ + E+ + R+ ++ R ++ KE ++ K++ E +ER +
Sbjct: 304 QRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQ 358
Score = 33.5 bits (75), Expect = 0.19
Identities = 19/89 (21%), Positives = 43/89 (48%), Gaps = 2/89 (2%)
Query: 161 KRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVSTEKLKNRKEK 220
+R P G ++S R + K + D ++++ +R++ + +T + K + R+EK
Sbjct: 28 RRRP--GSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREK 85
Query: 221 KSRDVVSKKEERKRTKKKKEQGQERTEEE 249
+ ER+R ++K+ + Q E +
Sbjct: 86 DRHRKRDRHRERQRDREKERERQTDRERD 114
Score = 31.2 bits (69), Expect = 0.94
Identities = 17/96 (17%), Positives = 45/96 (46%), Gaps = 5/96 (5%)
Query: 158 QKRKRHPEEGREK-----SEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVSTE 212
++R+R + R++ E ER + ++++ E + ++ + +R++ +
Sbjct: 277 KERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERD 336
Query: 213 KLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEE 248
+ K R+ K+ R +E ++T ++ + ER E
Sbjct: 337 REKERERKRKRQTEMDRERNRQTGREGRRQAERERE 372
>gi|168229156 NFKB activating protein [Homo sapiens]
Length = 415
Score = 45.1 bits (105), Expect = 6e-05
Identities = 29/119 (24%), Positives = 51/119 (42%), Gaps = 3/119 (2%)
Query: 133 EHRVYKHFSSDNSTSTHQASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKH 192
EH + ST++ S ++ +K R E +++ +++ SK K KK E+ D D
Sbjct: 159 EHTPVEDEEPKKSTTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSD-- 216
Query: 193 KSIQRKKTEVEIETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEEEML 251
S + E K K +K+K KK +K K+ + + ++EE L
Sbjct: 217 -SDSETDSSDEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQEEFL 274
Score = 28.9 bits (63), Expect = 4.7
Identities = 18/73 (24%), Positives = 35/73 (47%), Gaps = 2/73 (2%)
Query: 133 EHRVYKHFSSDNSTSTHQASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKH 192
+H+ Y S +S S +S + KR+ + +EK ++ RSK +KK ++ +
Sbjct: 205 KHKKYSEDSDSDSDSETDSSDED--NKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESS 262
Query: 193 KSIQRKKTEVEIE 205
S ++ E +E
Sbjct: 263 DSSSKESQEEFLE 275
>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
5 [Homo sapiens]
Length = 748
Score = 45.1 bits (105), Expect = 6e-05
Identities = 28/120 (23%), Positives = 61/120 (50%), Gaps = 9/120 (7%)
Query: 133 EHRVYKHFSSDNSTSTHQASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEE---IDL 189
E R ++ S++ ++ H++RKRH EE ++K+ E + KR++ E +
Sbjct: 73 EKRRHRSHSAEGGKHARVKEKEREHERRKRHREE-QDKARREWERQKRREMAREHSRRER 131
Query: 190 DKHKSIQRKKTEVEIETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEEE 249
D+ + ++RK+ E E+ K ++E+K R+ +++ ++R +++ RT E
Sbjct: 132 DRLEQLERKR-----ERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMRE 186
Score = 33.5 bits (75), Expect = 0.19
Identities = 21/96 (21%), Positives = 43/96 (44%), Gaps = 6/96 (6%)
Query: 154 KQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVSTEK 213
+Q+ +K K H + +E+ K KR+ + KH ++ K+ E E H +
Sbjct: 55 QQMSRKEKVHHRK------DEKRKEKRRHRSHSAEGGKHARVKEKEREHERRKRHREEQD 108
Query: 214 LKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEEE 249
R+ ++ + +E +R + + EQ + + E E
Sbjct: 109 KARREWERQKRREMAREHSRRERDRLEQLERKRERE 144
Score = 32.0 bits (71), Expect = 0.55
Identities = 27/101 (26%), Positives = 51/101 (50%), Gaps = 15/101 (14%)
Query: 157 HQKRKRHPEEGREKSEE-ERSKHKRKKSCEEIDLDKHKSIQRKKT-EVEIETVHVSTEKL 214
H+K ++ E+ R +S E KH R K +K + +R+K E + E+
Sbjct: 65 HRKDEKRKEKRRHRSHSAEGGKHARVK-------EKEREHERRKRHREEQDKARREWERQ 117
Query: 215 KNRK-----EKKSRDVVSKKE-ERKRTKKKKEQGQERTEEE 249
K R+ ++ RD + + E +R+R +K +EQ +E+ E++
Sbjct: 118 KRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQK 158
Score = 30.4 bits (67), Expect = 1.6
Identities = 24/116 (20%), Positives = 52/116 (44%), Gaps = 9/116 (7%)
Query: 134 HRVYKHFSSDNSTSTHQASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHK 193
HR + SD ++H + + + +GR+ +EE+ + + S DL
Sbjct: 181 HRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLS----DLQDIS 236
Query: 194 SIQRKKTEVEIETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEEE 249
+RK + E S+ + + E++ + ++EE +++ +E+ +E EEE
Sbjct: 237 DSERKTSSAES-----SSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEE 287
>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
2 [Homo sapiens]
Length = 782
Score = 45.1 bits (105), Expect = 6e-05
Identities = 28/120 (23%), Positives = 61/120 (50%), Gaps = 9/120 (7%)
Query: 133 EHRVYKHFSSDNSTSTHQASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEE---IDL 189
E R ++ S++ ++ H++RKRH EE ++K+ E + KR++ E +
Sbjct: 107 EKRRHRSHSAEGGKHARVKEKEREHERRKRHREE-QDKARREWERQKRREMAREHSRRER 165
Query: 190 DKHKSIQRKKTEVEIETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEEE 249
D+ + ++RK+ E E+ K ++E+K R+ +++ ++R +++ RT E
Sbjct: 166 DRLEQLERKR-----ERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMRE 220
Score = 33.5 bits (75), Expect = 0.19
Identities = 21/96 (21%), Positives = 43/96 (44%), Gaps = 6/96 (6%)
Query: 154 KQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVSTEK 213
+Q+ +K K H + +E+ K KR+ + KH ++ K+ E E H +
Sbjct: 89 QQMSRKEKVHHRK------DEKRKEKRRHRSHSAEGGKHARVKEKEREHERRKRHREEQD 142
Query: 214 LKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEEE 249
R+ ++ + +E +R + + EQ + + E E
Sbjct: 143 KARREWERQKRREMAREHSRRERDRLEQLERKRERE 178
Score = 32.0 bits (71), Expect = 0.55
Identities = 27/101 (26%), Positives = 51/101 (50%), Gaps = 15/101 (14%)
Query: 157 HQKRKRHPEEGREKSEE-ERSKHKRKKSCEEIDLDKHKSIQRKKT-EVEIETVHVSTEKL 214
H+K ++ E+ R +S E KH R K +K + +R+K E + E+
Sbjct: 99 HRKDEKRKEKRRHRSHSAEGGKHARVK-------EKEREHERRKRHREEQDKARREWERQ 151
Query: 215 KNRK-----EKKSRDVVSKKE-ERKRTKKKKEQGQERTEEE 249
K R+ ++ RD + + E +R+R +K +EQ +E+ E++
Sbjct: 152 KRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQK 192
Score = 30.4 bits (67), Expect = 1.6
Identities = 24/116 (20%), Positives = 52/116 (44%), Gaps = 9/116 (7%)
Query: 134 HRVYKHFSSDNSTSTHQASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHK 193
HR + SD ++H + + + +GR+ +EE+ + + S DL
Sbjct: 215 HRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLS----DLQDIS 270
Query: 194 SIQRKKTEVEIETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEEE 249
+RK + E S+ + + E++ + ++EE +++ +E+ +E EEE
Sbjct: 271 DSERKTSSAES-----SSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEE 321
>gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens]
Length = 569
Score = 44.7 bits (104), Expect = 8e-05
Identities = 29/116 (25%), Positives = 52/116 (44%), Gaps = 8/116 (6%)
Query: 133 EHRVYKHFSSDNSTSTHQASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKH 192
E Y D H+ K ++ + +E +EK EEE K + K EE + ++
Sbjct: 339 EDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKEEEEE 398
Query: 193 KSIQRKKTEVEIETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEE 248
+ +++K+ E EI KN +E +S+D + E+ + + + Q TEE
Sbjct: 399 EEMKQKEEEEEIRN--------KNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEE 446
Score = 37.4 bits (85), Expect = 0.013
Identities = 26/138 (18%), Positives = 61/138 (44%), Gaps = 29/138 (21%)
Query: 114 KPVPLNFNQQEYICGSHGVEHRVYKHFSSDNSTSTHQASH--KQIHQKRKRHPEEGREKS 171
KP+PL GV + ++ S N + + + Q+ +RH +++
Sbjct: 315 KPIPLP-----------GVRNIIFPFAPSPNEEESEDEEYYSEDEDQEARRHRLHSKDQR 363
Query: 172 EEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVSTEKLKNRKEKKSRDVVSKKEE 231
+ R+ + K EE ++ K + +++K+ ++E++ ++ K+EE
Sbjct: 364 KRMRAFQQEMKEKEEEEMKKEEEMKKKE----------------EKEEEEEEEMKQKEEE 407
Query: 232 RKRTKKKKEQGQERTEEE 249
+ K +E+G+ + EE+
Sbjct: 408 EEIRNKNEEEGESKDEED 425
Score = 29.3 bits (64), Expect = 3.6
Identities = 24/87 (27%), Positives = 40/87 (45%), Gaps = 7/87 (8%)
Query: 164 PEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVSTEKLKNRKEKKSR 223
P E+SE+E + + E H QRK+ + + K K +E K
Sbjct: 331 PSPNEEESEDEEY-YSEDEDQEARRHRLHSKDQRKRMRAFQQEM-----KEKEEEEMKKE 384
Query: 224 DVVSKKEERKRTKKKKEQGQERTEEEM 250
+ + KKEE K ++++E Q+ EEE+
Sbjct: 385 EEMKKKEE-KEEEEEEEMKQKEEEEEI 410
>gi|239752449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 170
Score = 43.9 bits (102), Expect = 1e-04
Identities = 34/116 (29%), Positives = 59/116 (50%), Gaps = 20/116 (17%)
Query: 129 SHGVEHRVYKHFSSDNSTSTHQASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEID 188
+H ++ +++ H S + H +H +R EE +EK +E++ K K+KK ++
Sbjct: 70 THRLKGKIF-HLISIAFCDAGPSLHLPLHGLPQR--EEKKEKEKEKKKKKKKKKKKKK-- 124
Query: 189 LDKHKSIQRKKTEVEIETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQE 244
K K ++KK + +K K RK K+ R +K ++KR KKKK+ G E
Sbjct: 125 --KKKKKKKKKKK----------KKKKKRKRKRKR---KRKRKKKRKKKKKKTGNE 165
Score = 34.3 bits (77), Expect = 0.11
Identities = 13/44 (29%), Positives = 31/44 (70%)
Query: 206 TVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEEE 249
++H+ L R+EKK ++ KK+++K+ KKKK++ +++ +++
Sbjct: 91 SLHLPLHGLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKK 134
Score = 32.3 bits (72), Expect = 0.42
Identities = 13/38 (34%), Positives = 27/38 (71%)
Query: 212 EKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEEE 249
EK K +K+KK + KK+++K+ KKKK++ +++ + +
Sbjct: 107 EKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRK 144
Score = 32.3 bits (72), Expect = 0.42
Identities = 13/38 (34%), Positives = 26/38 (68%)
Query: 212 EKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEEE 249
EK K +K+KK + KK+++K+ KKKK++ + + + +
Sbjct: 111 EKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRK 148
Score = 32.0 bits (71), Expect = 0.55
Identities = 13/38 (34%), Positives = 26/38 (68%)
Query: 212 EKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEEE 249
EK K +K+KK + KK+++K+ KKKK++ + + + +
Sbjct: 109 EKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRK 146
Score = 31.2 bits (69), Expect = 0.94
Identities = 13/55 (23%), Positives = 34/55 (61%)
Query: 195 IQRKKTEVEIETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEEE 249
+ +++ + E E +K K +K+KK + KK+++K+ K+K+++ ++R ++
Sbjct: 99 LPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKK 153
Score = 30.4 bits (67), Expect = 1.6
Identities = 14/63 (22%), Positives = 36/63 (57%)
Query: 187 IDLDKHKSIQRKKTEVEIETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERT 246
+ L H QR++ + + + +K K +K+KK + KK+++K+ +K+K + + +
Sbjct: 92 LHLPLHGLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKR 151
Query: 247 EEE 249
+++
Sbjct: 152 KKK 154
>gi|239750213 PREDICTED: hypothetical protein [Homo sapiens]
Length = 248
Score = 43.9 bits (102), Expect = 1e-04
Identities = 24/103 (23%), Positives = 58/103 (56%), Gaps = 3/103 (2%)
Query: 149 HQASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVH 208
H + K+ KR R + ++K +++ + K+KK+ + K + +K+T +T
Sbjct: 14 HVITEKESAWKRGRKKKTTKKKKKKKTTMKKKKKTTTK---KKTTTKTKKRTTTTKKTTT 70
Query: 209 VSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEEEML 251
+T++ + KEK+ K++E+++ KKKK++ +++ +++ L
Sbjct: 71 TTTKEKEKEKEKEKEKEKEKEKEKEKEKKKKKKKKKKKKKKKL 113
Score = 33.1 bits (74), Expect = 0.25
Identities = 16/40 (40%), Positives = 24/40 (60%)
Query: 202 VEIETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQ 241
V +E VHV TEK K + + KK+++K T KKK++
Sbjct: 8 VAMEKVHVITEKESAWKRGRKKKTTKKKKKKKTTMKKKKK 47
Score = 33.1 bits (74), Expect = 0.25
Identities = 22/107 (20%), Positives = 47/107 (43%), Gaps = 4/107 (3%)
Query: 138 KHFSSDNSTSTHQASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQR 197
K ++ T+T K+ +++++ E+ +EK +E+ K K+KK ++ K K +
Sbjct: 60 KRTTTTKKTTTTTTKEKEKEKEKEKEKEKEKEKEKEKEKKKKKKKKKKK----KKKKLNA 115
Query: 198 KKTEVEIETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQE 244
K +EI + T E++ V + + + G+E
Sbjct: 116 KVCGLEIASWSEMTTAAAGEGEEQGSMVQAAGVSISNSSPSRSDGKE 162
Score = 31.2 bits (69), Expect = 0.94
Identities = 16/51 (31%), Positives = 27/51 (52%)
Query: 188 DLDKHKSIQRKKTEVEIETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKK 238
+LDK ++++ E E+ K K K+KK + KK+++ TKKK
Sbjct: 3 ELDKGVAMEKVHVITEKESAWKRGRKKKTTKKKKKKKTTMKKKKKTTTKKK 53
Score = 28.1 bits (61), Expect = 8.0
Identities = 19/92 (20%), Positives = 43/92 (46%), Gaps = 6/92 (6%)
Query: 146 TSTHQASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIE 205
T+ + K +K+K+ + + ++ ++ KK+ +K K +++K + + +
Sbjct: 31 TTKKKKKKKTTMKKKKKTTTKKKTTTKTKKRTTTTKKTTTTTTKEKEKEKEKEKEKEKEK 90
Query: 206 TVHVSTEKLKNRKEKKSRDVVSKKEERKRTKK 237
EK K +K+KK KK+++K K
Sbjct: 91 EKEKEKEKKKKKKKKK------KKKKKKLNAK 116
>gi|21396500 HIRA interacting protein 3 [Homo sapiens]
Length = 556
Score = 43.5 bits (101), Expect = 2e-04
Identities = 34/117 (29%), Positives = 54/117 (46%), Gaps = 10/117 (8%)
Query: 143 DNSTSTHQASHKQIHQKRKRH--PEEGREKSEEERSKHK---RKKSCEEIDLDKHKSIQR 197
+N +A + ++R+R + G E SEEE +K RKK + S+ R
Sbjct: 130 ENPRRASKAVEESSDEERQRDLPAQRGEESSEEEEKGYKGKTRKKPVVKKQAPGKASVSR 189
Query: 198 KKT-----EVEIETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEEE 249
K+ E E E V + +K++ K KS ++ E + +KKEQ +E EEE
Sbjct: 190 KQAREESEESEAEPVQRTAKKVEGNKGTKSLKESEQESEEEILAQKKEQREEEVEEE 246
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 43.1 bits (100), Expect = 2e-04
Identities = 32/107 (29%), Positives = 60/107 (56%), Gaps = 6/107 (5%)
Query: 154 KQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHK-SIQRKKTEVEIETVHVSTE 212
++IH++ K EE R++ EE + ++ + EEI K K Q +K + E + E
Sbjct: 505 EKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEE 564
Query: 213 KLKNRKEK--KSRDVVSKKEERKRTKKKKEQGQE---RTEEEMLWDQ 254
K+ +++EK + + V ++EE+ R +++K + QE R +EEM +Q
Sbjct: 565 KMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQ 611
Score = 42.0 bits (97), Expect = 5e-04
Identities = 26/111 (23%), Positives = 58/111 (52%), Gaps = 8/111 (7%)
Query: 149 HQASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVH 208
H K Q+ K +E + + +EE+ + + +K E+ ++ + Q +K + E +
Sbjct: 567 HDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQE---QEEKMGEQEEKMC 623
Query: 209 VSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTE-----EEMLWDQ 254
EK++ ++EK R +E+ K+ ++++E+ +E+ E EE +W+Q
Sbjct: 624 EQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQ 674
Score = 40.4 bits (93), Expect = 0.002
Identities = 24/108 (22%), Positives = 59/108 (54%), Gaps = 9/108 (8%)
Query: 158 QKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEI----ETVHVSTEK 213
Q+ K +E + +EE+ + +K CE+ + + + + ++ E +I + + EK
Sbjct: 597 QEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEK 656
Query: 214 LKNRKE--KKSRDVVSKKEERKRTKKKKEQGQE---RTEEEMLWDQSI 256
++ ++E ++ + + ++EE+ +++K Q QE R +EE +W+Q +
Sbjct: 657 IREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEV 704
Score = 39.7 bits (91), Expect = 0.003
Identities = 31/110 (28%), Positives = 60/110 (54%), Gaps = 9/110 (8%)
Query: 154 KQIHQKRKRHPEEGREKSEEE---RSKHKRKKSCEEIDLDKHK-SIQRKKTEVEIETVHV 209
K Q+ K H +E + + +EE R + K ++ E+I + K Q + T+ + E +
Sbjct: 558 KMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGE 617
Query: 210 STEKLKNRKEK--KSRDVVSKKEERKRTKKKKEQGQE---RTEEEMLWDQ 254
EK+ ++EK + + + ++EE+ R ++KK + QE R +EEM+ +Q
Sbjct: 618 QEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQ 667
Score = 38.9 bits (89), Expect = 0.005
Identities = 23/97 (23%), Positives = 51/97 (52%), Gaps = 5/97 (5%)
Query: 158 QKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVSTEKLKNR 217
+++ R EE + E+ R + ++++ E+I + + Q K + E + EK++ +
Sbjct: 437 EEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQ 496
Query: 218 KEKKSRDVVSKKEERKRTKKKKEQGQERTEEEMLWDQ 254
+EK R +EE+ ++K + ++R E+E +W Q
Sbjct: 497 EEKMWR-----QEEKIHEQEKIREEEKRQEQEEMWRQ 528
Score = 38.5 bits (88), Expect = 0.006
Identities = 25/108 (23%), Positives = 56/108 (51%), Gaps = 11/108 (10%)
Query: 158 QKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRK---------KTEVEIETVH 208
+K + E+ RE+ E+ R + ++ + EE+ +K + ++R+ K + E +
Sbjct: 375 EKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMW 434
Query: 209 VSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEEE--MLWDQ 254
EK++ +EK +++E KR +++K + QE+ +E+ +W Q
Sbjct: 435 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQ 482
Score = 38.1 bits (87), Expect = 0.008
Identities = 25/106 (23%), Positives = 56/106 (52%), Gaps = 7/106 (6%)
Query: 150 QASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHV 209
+ K Q++ R EE R++ E+ R + KR++ +E + + Q +K + E +
Sbjct: 442 ELEEKMHEQEKIREQEEKRQEEEKIREQEKRQE--QEAKMWR----QEEKIREQEEKIRE 495
Query: 210 STEKLKNRKEK-KSRDVVSKKEERKRTKKKKEQGQERTEEEMLWDQ 254
EK+ ++EK ++ + ++E+R+ ++ Q ++ E+E +W Q
Sbjct: 496 QEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQ 541
Score = 36.6 bits (83), Expect = 0.022
Identities = 25/105 (23%), Positives = 56/105 (53%), Gaps = 9/105 (8%)
Query: 154 KQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEV-EIETVHVSTE 212
++I ++ ++ E+ + +E H+++K EE + + + R++ ++ E E + E
Sbjct: 484 EKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKE 543
Query: 213 KLKNRKEKKSRDVVSKKEERKRTKKKKEQGQE---RTEEEMLWDQ 254
K+ ++EK + K+EE+ +++K QE R +EE +W Q
Sbjct: 544 KIHEQEEK-----IRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQ 583
Score = 36.6 bits (83), Expect = 0.022
Identities = 23/117 (19%), Positives = 54/117 (46%), Gaps = 4/117 (3%)
Query: 135 RVYKHFSSDNSTSTHQASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKS 194
R + + + + K Q+ K +E + + +EE+ + + KK E+ + + +
Sbjct: 602 REQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQE 661
Query: 195 IQRKKTEVEI----ETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTE 247
++ E ++ E + EK++ ++EK R E+ R ++++E+ QE E
Sbjct: 662 EMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQE 718
Score = 33.5 bits (75), Expect = 0.19
Identities = 22/90 (24%), Positives = 51/90 (56%), Gaps = 7/90 (7%)
Query: 172 EEERSKHKRKKSCEEIDLDKHKSIQR--KKTEVEIETVHVSTEKLKNRKEKKSR--DVVS 227
EE ++ + EE + + IQ +K + + E + EK++ ++EK R +++
Sbjct: 347 EENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMW 406
Query: 228 KKEERKRTKKK---KEQGQERTEEEMLWDQ 254
+KEE+ R +++ +++ + R +EEM+W++
Sbjct: 407 EKEEKMRRQEEMMWEKEEKMRRQEEMMWEK 436
Score = 33.1 bits (74), Expect = 0.25
Identities = 21/103 (20%), Positives = 53/103 (51%), Gaps = 4/103 (3%)
Query: 158 QKRKRHPEEGREKSEEERSKHKRKK--SCEEIDLDKHKSIQRKKTEV--EIETVHVSTEK 213
QK K H +E + + +EE+ + +K EE ++ + + R++ ++ + E + EK
Sbjct: 541 QKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEK 600
Query: 214 LKNRKEKKSRDVVSKKEERKRTKKKKEQGQERTEEEMLWDQSI 256
++ ++E E+ ++ +++E+ QE+ E+ ++ I
Sbjct: 601 IREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKI 643
Score = 32.7 bits (73), Expect = 0.32
Identities = 26/112 (23%), Positives = 55/112 (49%), Gaps = 8/112 (7%)
Query: 150 QASHKQIHQKRKRHPEEGREKSEEERSKHKRKK--SCEEIDLDKHKSIQRKKTEVEIETV 207
+ K Q+ +E + + +EE K +K EE+ +K + I R+ E E
Sbjct: 393 EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKI-RELEEKMHEQE 451
Query: 208 HVSTEKLKNRKEKKSRDVVSKKEE-----RKRTKKKKEQGQERTEEEMLWDQ 254
+ ++ K ++E+K R+ ++E+ R+ K ++++ + R +EE +W Q
Sbjct: 452 KIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQ 503
>gi|155969714 nuclear protein, ataxia-telangiectasia locus [Homo
sapiens]
Length = 1427
Score = 43.1 bits (100), Expect = 2e-04
Identities = 41/220 (18%), Positives = 81/220 (36%), Gaps = 24/220 (10%)
Query: 20 KVQKARGLEPKTCFRKMKGDYLETCGYKGEVNSRPTYRMFDQRLPSETIQTYPRSCNIPQ 79
K QKA+GL K C K + +++ G+ +++ T + D+ + ++ + +P
Sbjct: 990 KSQKAQGLRNKPCIGKQVNNLVDSSGHSVGCHAQKT-EVSDKSIATD-LGKKSEETTVPF 1047
Query: 80 TVENRLPQWLPAHDSRLRLDSLSYCQFTRDCFSEKPVPLNFNQQEYICGSHGVEHRVYKH 139
E+ +P P H L CF P + + G H++
Sbjct: 1048 PEESIVPAAKPCHRRVL-------------CFDSTTAP--------VANTQGPNHKMVSQ 1086
Query: 140 FSSDNSTSTHQASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKK 199
N+ S + K P K E+E+ + S E + +H +I+ +
Sbjct: 1087 NKERNAVSFPNLDSPNVSSTLK-PPSNNAIKREKEKPPLPKILSKSESAISRHTTIRETQ 1145
Query: 200 TEVEIETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKK 239
+E ++ + E K ++ S E +K + K
Sbjct: 1146 SEKKVSPTEIVLESFHKATANKENELCSDVERQKNPENSK 1185
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 43.1 bits (100), Expect = 2e-04
Identities = 22/80 (27%), Positives = 38/80 (47%)
Query: 172 EEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVSTEKLKNRKEKKSRDVVSKKEE 231
+EE+ +HK S D S + + ++ + EK K RK+K ++ K+E
Sbjct: 185 KEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRKHKKE 244
Query: 232 RKRTKKKKEQGQERTEEEML 251
+K+ KK K+ +E E L
Sbjct: 245 KKKRKKSKKSASSESEAENL 264
Score = 42.7 bits (99), Expect = 3e-04
Identities = 27/118 (22%), Positives = 56/118 (47%), Gaps = 2/118 (1%)
Query: 133 EHRVYKHFSSDNSTSTHQASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKH 192
E ++ H + S + K++ + E ++ E+ K+K K +
Sbjct: 403 ERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRS 462
Query: 193 KSIQRKKTEVEIETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKK-KEQGQERTEEE 249
KS ++ K++ E ++ H E+ + R K RD + KE+ K++ K K+Q + R++E+
Sbjct: 463 KSKEKSKSK-ERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEK 519
Score = 38.1 bits (87), Expect = 0.008
Identities = 22/101 (21%), Positives = 50/101 (49%), Gaps = 4/101 (3%)
Query: 141 SSDNSTSTHQASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKT 200
SS +S+ + A+ ++ +++K+H + R+ +E++ + K KKS ++ Q + T
Sbjct: 212 SSSDSSDSESATEEKSKKRKKKHRKNSRKHKKEKKKRKKSKKSASSESEAENLEAQPQST 271
Query: 201 EVEIETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQ 241
E + + RK D ++ERK ++++E+
Sbjct: 272 VRPEEIPPIPENRFLMRKSPPKAD----EKERKNRERERER 308
Score = 37.4 bits (85), Expect = 0.013
Identities = 31/127 (24%), Positives = 55/127 (43%), Gaps = 12/127 (9%)
Query: 133 EHRVYKHFSSDNSTSTHQASHKQIHQKRK---------RHPEEGREKSEEERSKHKRKKS 183
E +V H S+ + S K K K R + + KS+E SKH R +
Sbjct: 423 EKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEE 482
Query: 184 CEEIDLDKHKSIQRKKTEVEIETVHVSTEKLKNRKEKKSRDVVSKKEE--RKRTKKKKEQ 241
K + + K E E ++ ++ ++R ++KS+ + SK E ++K+K +
Sbjct: 483 KRMRSRSKGRDHENVK-EKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRR 541
Query: 242 GQERTEE 248
Q R+ E
Sbjct: 542 AQSRSRE 548
Score = 34.7 bits (78), Expect = 0.085
Identities = 29/122 (23%), Positives = 55/122 (45%), Gaps = 18/122 (14%)
Query: 141 SSDNSTSTHQAS-HKQIHQKRKRHPEEGRE----KSEEERSKHKRKKSCEEIDLDKHKSI 195
S + S S + S H + +KR R +GR+ K +E++S K K +K K +
Sbjct: 464 SKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQL 523
Query: 196 QRKKTEVEIETVHVSTEKLKNRKEKKSRD---------VVSKKEERKRTKKKKEQGQERT 246
+ K E + H +++ R + +SR+ S+ ER R++ + + + RT
Sbjct: 524 ESKSNEHD----HSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRT 579
Query: 247 EE 248
+
Sbjct: 580 HD 581
Score = 33.9 bits (76), Expect = 0.15
Identities = 21/96 (21%), Positives = 47/96 (48%), Gaps = 8/96 (8%)
Query: 160 RKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVSTEKLKNRKE 219
++R + R SE K++++K ++ HKS +++ +I +K KN+ +
Sbjct: 402 KERKITDHRNVSESPNRKNEKEKKVKD-----HKSNSKER---DIRRNSEKDDKYKNKVK 453
Query: 220 KKSRDVVSKKEERKRTKKKKEQGQERTEEEMLWDQS 255
K+++ K + K K+++ R EE+ + +S
Sbjct: 454 KRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRS 489
Score = 33.5 bits (75), Expect = 0.19
Identities = 51/257 (19%), Positives = 95/257 (36%), Gaps = 14/257 (5%)
Query: 4 SKKTYDSFQDELEDYIKVQKARGLEPKTCFRKMKGDYLETCGYKGEVNSRPTYRMFDQRL 63
S DS D E K+ RK K K + + + +
Sbjct: 200 SSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRKHKKEKKKRKKSKKSASSES 259
Query: 64 PSETIQTYPRSC----NIPQTVENR--LPQWLPAHDSRLRLDSLSYCQFTRDCFSEKPVP 117
+E ++ P+S IP ENR + + P D + R + + R+C P
Sbjct: 260 EAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERKNRER--ERERECNPPNSQP 317
Query: 118 LNFNQQEYICGS----HGVEHRVYKHFSSDNSTSTHQASHKQIHQKRKRHPEEGREKSEE 173
++ ++ + S G R Y+ S S + S H +++ + S
Sbjct: 318 ASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSG 377
Query: 174 ERSKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVSTEKLKNRKEKKSRDVVSKKEER- 232
ER K EI ++ ++ K+ ++ + KN KEKK +D S +ER
Sbjct: 378 ERWIKGDKSELNEIKENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERD 437
Query: 233 -KRTKKKKEQGQERTEE 248
+R +K ++ + + ++
Sbjct: 438 IRRNSEKDDKYKNKVKK 454
Score = 32.7 bits (73), Expect = 0.32
Identities = 28/121 (23%), Positives = 54/121 (44%), Gaps = 11/121 (9%)
Query: 138 KHFSSDNSTSTHQASHKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKHKSIQR 197
+H SS +S+S+ S + + E + EE+SK ++KK + K + +R
Sbjct: 190 RHKSSSSSSSSSSDSDSSSDSQSSSDSSDS-ESATEEKSKKRKKKHRKNSRKHKKEKKKR 248
Query: 198 KK------TEVEIETVHVSTEKLKNRKE----KKSRDVVSKKEERKRTKKKKEQGQERTE 247
KK +E E E + + +E ++R ++ K + K++K + +ER
Sbjct: 249 KKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERKNRERERER 308
Query: 248 E 248
E
Sbjct: 309 E 309
Score = 31.6 bits (70), Expect = 0.72
Identities = 23/99 (23%), Positives = 48/99 (48%), Gaps = 15/99 (15%)
Query: 153 HKQIHQKRKRHPEEGREKSEEERSKHKRKKSCEEIDLDKH---------KSIQRKKTEVE 203
H+ + +K K+ +G++ +ERS+ K K E ++H + Q + E +
Sbjct: 494 HENVKEKEKQSDSKGKD---QERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECD 550
Query: 204 I---ETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKK 239
I + + S + ++R +SR V S+ +R R++ K+
Sbjct: 551 ITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKE 589
Score = 30.4 bits (67), Expect = 1.6
Identities = 29/136 (21%), Positives = 55/136 (40%), Gaps = 19/136 (13%)
Query: 128 GSHGVEHRVYKHFSS-DNSTSTHQASH-------KQIHQKRKR-HPEEGREKSEEER--- 175
G H R + S D S +H K+ H+ R++ + GR +S E R
Sbjct: 554 GKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPP 613
Query: 176 ----SKHKRKKSCEEIDLDKHKSIQRKKTEVEIETVHVSTEKLKNRKEKKSRDVVSKKEE 231
SK +R++ + ++ +S R K + + S K + EK+ + SK +
Sbjct: 614 GRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSESEKR---MYSKSRD 670
Query: 232 RKRTKKKKEQGQERTE 247
+ +E+ +R +
Sbjct: 671 HNSSNNSREKKADRDQ 686
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.128 0.372
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,813,101
Number of Sequences: 37866
Number of extensions: 537675
Number of successful extensions: 11519
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 373
Number of HSP's successfully gapped in prelim test: 618
Number of HSP's that attempted gapping in prelim test: 4836
Number of HSP's gapped (non-prelim): 4575
length of query: 259
length of database: 18,247,518
effective HSP length: 100
effective length of query: 159
effective length of database: 14,460,918
effective search space: 2299285962
effective search space used: 2299285962
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.