Guide to the Human Genome
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Search of human proteins with 7705268

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7705268 family with sequence similarity 8, member A1 [Homo
sapiens]
         (413 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7705268 family with sequence similarity 8, member A1 [Homo sa...   838   0.0  
gi|14249464 zinc finger and BTB domain containing 45 [Homo sapiens]    49   6e-06
gi|163965366 nascent polypeptide-associated complex alpha subuni...    48   2e-05
gi|149773456 hypothetical protein LOC643314 [Homo sapiens]             47   3e-05
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ...    47   3e-05
gi|14249622 ajuba isoform 1 [Homo sapiens]                             46   5e-05
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    46   7e-05
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    45   9e-05
gi|241982780 programmed cell death 6 interacting protein isoform...    45   1e-04
gi|22027538 programmed cell death 6 interacting protein isoform ...    45   1e-04
gi|239754516 PREDICTED: hypothetical protein [Homo sapiens]            44   4e-04
gi|206597556 kelch domain containing 7B [Homo sapiens]                 44   4e-04
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]      43   5e-04
gi|116734706 interferon regulatory factor 2 binding protein 2 is...    43   5e-04
gi|116734704 interferon regulatory factor 2 binding protein 2 is...    43   5e-04
gi|239754042 PREDICTED: similar to hCG1646049 [Homo sapiens]           43   6e-04
gi|239748572 PREDICTED: similar to hCG1646049 [Homo sapiens]           43   6e-04
gi|169167670 PREDICTED: similar to hCG1646049 [Homo sapiens]           43   6e-04
gi|210032580 SET domain containing 1B [Homo sapiens]                   43   6e-04
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    42   8e-04
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    42   8e-04
gi|61966741 TMF regulated nuclear protein [Homo sapiens]               42   0.001
gi|27894344 nuclear receptor subfamily 4, group A, member 1 [Hom...    42   0.001
gi|21361342 nuclear receptor subfamily 4, group A, member 1 [Hom...    42   0.001
gi|116268127 kinase non-catalytic C-lobe domain (KIND) containin...    41   0.002
gi|85815829 SH3-domain binding protein 1 [Homo sapiens]                41   0.002
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    40   0.003
gi|239749077 PREDICTED: hypothetical protein XP_002346898 [Homo ...    40   0.004
gi|239743103 PREDICTED: hypothetical protein XP_002342755 [Homo ...    40   0.004
gi|239508758 PREDICTED: hypothetical protein [Homo sapiens]            40   0.004

>gi|7705268 family with sequence similarity 8, member A1 [Homo
           sapiens]
          Length = 413

 Score =  838 bits (2166), Expect = 0.0
 Identities = 413/413 (100%), Positives = 413/413 (100%)

Query: 1   MAEGPEEARGHPPGQDDGGGDHEPVPSLRGPPTTAVPCPRDDPQAEPQAPGRPTAPGLAA 60
           MAEGPEEARGHPPGQDDGGGDHEPVPSLRGPPTTAVPCPRDDPQAEPQAPGRPTAPGLAA
Sbjct: 1   MAEGPEEARGHPPGQDDGGGDHEPVPSLRGPPTTAVPCPRDDPQAEPQAPGRPTAPGLAA 60

Query: 61  AAAADKLEPPRELRKRGEAASGSGAELQEQAGCEAPEAAAPRERPARLSAREYSRQVHEW 120
           AAAADKLEPPRELRKRGEAASGSGAELQEQAGCEAPEAAAPRERPARLSAREYSRQVHEW
Sbjct: 61  AAAADKLEPPRELRKRGEAASGSGAELQEQAGCEAPEAAAPRERPARLSAREYSRQVHEW 120

Query: 121 LWQSYCGYLTWHSGLAAFPAYCSPQPSPQSFPSGGAAVPQAAAPPPPQLGYYNPFYFLSP 180
           LWQSYCGYLTWHSGLAAFPAYCSPQPSPQSFPSGGAAVPQAAAPPPPQLGYYNPFYFLSP
Sbjct: 121 LWQSYCGYLTWHSGLAAFPAYCSPQPSPQSFPSGGAAVPQAAAPPPPQLGYYNPFYFLSP 180

Query: 181 GAAGPDPRTAAGISTPAPVAGLGPRAPHVQASVRATPVTRVGSAAPSRSPSETGRQAGRE 240
           GAAGPDPRTAAGISTPAPVAGLGPRAPHVQASVRATPVTRVGSAAPSRSPSETGRQAGRE
Sbjct: 181 GAAGPDPRTAAGISTPAPVAGLGPRAPHVQASVRATPVTRVGSAAPSRSPSETGRQAGRE 240

Query: 241 YVIPSLAHRFMAEMVDFFILFFIKATIVLSIMHLSGIKDISKFAMHYIIEEIDEDTSMED 300
           YVIPSLAHRFMAEMVDFFILFFIKATIVLSIMHLSGIKDISKFAMHYIIEEIDEDTSMED
Sbjct: 241 YVIPSLAHRFMAEMVDFFILFFIKATIVLSIMHLSGIKDISKFAMHYIIEEIDEDTSMED 300

Query: 301 LQKMMVVALIYRLLVCFYEIICIWGAGGATPGKFLLGLRVVTCDTSVLIAPSRVLVIPSS 360
           LQKMMVVALIYRLLVCFYEIICIWGAGGATPGKFLLGLRVVTCDTSVLIAPSRVLVIPSS
Sbjct: 301 LQKMMVVALIYRLLVCFYEIICIWGAGGATPGKFLLGLRVVTCDTSVLIAPSRVLVIPSS 360

Query: 361 NVSITTSTIRALIKNFSIASFFPAFITLLFFQHNRTAYDIVAGTIVVKRNGVR 413
           NVSITTSTIRALIKNFSIASFFPAFITLLFFQHNRTAYDIVAGTIVVKRNGVR
Sbjct: 361 NVSITTSTIRALIKNFSIASFFPAFITLLFFQHNRTAYDIVAGTIVVKRNGVR 413


>gi|14249464 zinc finger and BTB domain containing 45 [Homo sapiens]
          Length = 511

 Score = 49.3 bits (116), Expect = 6e-06
 Identities = 71/259 (27%), Positives = 93/259 (35%), Gaps = 50/259 (19%)

Query: 10  GHPPGQDDGGGDHEPVP-SLRGPPTTAVPCPRDDPQAEPQAPGRPTAPGLAAAAAADKLE 68
           GHP G        +P    L  PPT   P   + P A+P     P   G       D+ +
Sbjct: 163 GHP-GAAHSRKQRQPARLQLPAPPT---PAKAEGPDADPSLSAAPDDRG-------DEDD 211

Query: 69  PPRELRKRGEAASGSGAELQEQAGCEAPEAAAP----------RERPARLSAREYSRQVH 118
              +    GE   G G   + QA    P+ AA            E PA     +YS    
Sbjct: 212 EESDDETDGEDGEGGGPG-EGQAPPSFPDCAAGFLTAAADSACEEPPAPTGLADYSGAGR 270

Query: 119 EWLW----------QSYCGYLTWHSGLAAFPAYCSPQ-PSPQSFPSGGAAVPQAAAPPPP 167
           ++L            SY    TWH    A P  C  + P        G+  P    P PP
Sbjct: 271 DFLRGAGSAEDVFPDSYVS--TWHDEDGAVPEGCPTETPVQPDCILSGSRPPGVKTPGPP 328

Query: 168 QLGYYNPFYFLSPGAAGPDPRTAAGISTPAPVAGLGPRAPHVQASVRATPVTRVG----- 222
              +  PF+  +PG   P P   +G   PAP     P A +      A P T++G     
Sbjct: 329 VALF--PFHLGAPGPPAPPPSAPSG-PAPAP-----PPAFYPTLQPEAAPSTQLGEVPAP 380

Query: 223 SAAPSRSPSET-GRQAGRE 240
           SAAP+ +PS T  R  G E
Sbjct: 381 SAAPTTAPSGTPARTPGAE 399


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 57/218 (26%), Positives = 80/218 (36%), Gaps = 27/218 (12%)

Query: 26   PSLRGPPTTAVPCPRDDPQAE--PQAPGRPTAPGLAAAAAADKLEPPRELRKRGEAASGS 83
            PS +G P T  P     P A   P   G P  P    A     + PP        +  GS
Sbjct: 971  PSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPP--------SPKGS 1022

Query: 84   GAELQEQAGCEAPEAA---APRERPARLSAREYSRQVHEWLWQSYCGYLTWHSGLAAFPA 140
             A      G   P AA   +P+  PA     + +         S  G     S   A   
Sbjct: 1023 PAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTP 1082

Query: 141  YCSPQPSPQSFPSG----GAAVPQAAAPPPPQLGYYNPFYF---LSPGAAGPDPRTAAGI 193
              +  PSP+  P+     GA +P AA PP P+ G   P +     +P A  P P+   G+
Sbjct: 1083 PAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPK--GGL 1140

Query: 194  STPAPVAGLGPRAPHVQASVRATPVTRVGSAAPSRSPS 231
            +TP P       AP   A+   +P   + +  P  +P+
Sbjct: 1141 ATPPPKG-----APTTPAATPPSPKGGLATPPPKGAPT 1173



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 61/260 (23%), Positives = 85/260 (32%), Gaps = 68/260 (26%)

Query: 12   PPGQDDGGGDHEPVPSLRGP--PTTAVPCPRD--------DPQAEPQAPGRPTAPGLAAA 61
            PP +    G   P+ +L  P  P  A   P +        D  A   +P  P+  G    
Sbjct: 808  PPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTP 867

Query: 62   AAADKLEPPRELRKRGEAASGSGAELQEQAGCEAPEAAAPRERPARLSAREYSRQVHEWL 121
            +A   L P        E  + S   L      E P   AP++ PA               
Sbjct: 868  SAVTPLSPKGVTLPPKETPTPSVVNLPFPK--EGPATPAPKQAPAL-------------- 911

Query: 122  WQSYCGYLTWHSGLAAFPAYCSPQPSPQSFPSG----GAAVPQAAAPPPPQLGYYNPFYF 177
                       S  ++ P      P+P+  P+     GA  P AA PP P+ G   P   
Sbjct: 912  -----------SMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPK 960

Query: 178  LSP------------GAAGPDPRTA------------AGISTPAPVAGLGPRA---PHVQ 210
             +P            G A P P+ A             G +TP+P     P A   P  +
Sbjct: 961  WAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPK 1020

Query: 211  ASVRATPVTRVGSAAPSRSP 230
             S  ATP  +  S  P+ +P
Sbjct: 1021 GSPAATPFPKGASTPPAATP 1040



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 58/230 (25%), Positives = 71/230 (30%), Gaps = 53/230 (23%)

Query: 26   PSLRGPPTT--AVPCPRDDPQAEPQAPGRPTAPGLAAAAAADKLEPPRELRKRGEAASG- 82
            PS +G PTT  A P       A P   G PT P     +    L  P         A+  
Sbjct: 1189 PSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP 1248

Query: 83   ----SGAELQEQAGCEAPEAAAPRERPARLSAREYSRQVHEWLWQSYCGYLTWHSGLAAF 138
                 G       G   P AA P      L+                      H G A  
Sbjct: 1249 PSPKGGPATPPPKGAPTPPAATPPSLKGGLATPP-------------------HKG-APN 1288

Query: 139  PAYC---SPQPSPQSFPSGGAAVPQAAAPP--------PPQLGYYNPFYFLSPGAAGPDP 187
            PA     SP+  P + P  GA  P AA PP        PP  G   P     P    P P
Sbjct: 1289 PAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTP-----PAVTPPSP 1343

Query: 188  RTAAGISTPAPVAGLGPRAPHVQASVRATPVTRVGSAAPSRSPSETGRQA 237
            +    +    P +  GP           TP ++ G   P+ +PS  G  A
Sbjct: 1344 KGTPTLPATTPSSKGGP----------TTPSSKEGPTPPAATPSHKGGPA 1383



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 60/223 (26%), Positives = 75/223 (33%), Gaps = 40/223 (17%)

Query: 19   GGDHEPVPSLRGPPTT--AVPCPRDDPQAEPQAPGRPTAPGLAAAAAADKLEPPRELRKR 76
            GG   P P  +G PTT  A P       A P   G PT P     +    L  P     +
Sbjct: 1138 GGLATPPP--KGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSP---K 1192

Query: 77   GEAASGSGAELQEQAGCEAPEAAAPRERPARLSAREYSRQVHEWLWQSYCGYLTWHS--G 134
            G   + +      + G   P   +P+  P   +A   S +          G L   S  G
Sbjct: 1193 GAPTTPAATPPSPKGGLATP---SPKGAPTTPAATPPSPK----------GGLATPSPKG 1239

Query: 135  LAAFPAYCSPQPS--PQSFPSGGAAVPQAAAPP--------PPQLGYYNPFYFLSPGAAG 184
                PA   P P   P + P  GA  P AA PP        PP  G  NP     P   G
Sbjct: 1240 APTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKG 1299

Query: 185  PDPRTAAGISTPAPVAGLGPRAPHVQASVRATPVTRVGSAAPS 227
              P T+     P P A   P       S + +P T     AP+
Sbjct: 1300 -GPATSPPKGAPTPPAATPP-------SPKGSPGTPPPKGAPT 1334



 Score = 39.3 bits (90), Expect = 0.007
 Identities = 58/237 (24%), Positives = 72/237 (30%), Gaps = 75/237 (31%)

Query: 26   PSLRGPPTTAV---PCPRDDPQAEPQAPGRPTAPGLAAAAAADKLEPPRELRKRGEA--- 79
            PS +G PTT     P P+  P A P   G PT P     +    L  P        A   
Sbjct: 1235 PSPKGAPTTPAATPPSPKGGP-ATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVT 1293

Query: 80   --ASGSGAELQEQAGCEAPEAAAPRERPARLSAREYSRQVHEWLWQSYCGYLTWHSGLAA 137
              +   G       G   P AA P                                    
Sbjct: 1294 PPSPKGGPATSPPKGAPTPPAATPP----------------------------------- 1318

Query: 138  FPAYCSPQPSPQSFPSGGAAVPQAAAPPPPQLGYYNPFYFLS---------------PGA 182
                 SP+ SP + P  GA  P A  PP P+     P    S               P A
Sbjct: 1319 -----SPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPA 1373

Query: 183  AGPDPRTAAGISTPAPVAGLG-------PRAPHV----QASVRATPVTRVGSAAPSR 228
            A P  +    ++ P+P  G         P +P V         ATPVTR G+A PS+
Sbjct: 1374 ATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSK 1430



 Score = 38.5 bits (88), Expect = 0.011
 Identities = 67/273 (24%), Positives = 98/273 (35%), Gaps = 62/273 (22%)

Query: 8    ARGHP--PGQDDGGGDHEPVPSLRGPPTTAVPCPRDDPQAEPQAPGRPTAPGLAAAAAAD 65
            ++G P  P   +G       PS +G P    P P+  P A P   G PT+P  A    + 
Sbjct: 1356 SKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGP-AIPSPKGDPTSP--AVIPLSP 1412

Query: 66   KLEPPRELRKRGEAASGSGAELQEQAGC-----EAPEAAAPRERPARLSAREYSRQVHEW 120
            K  P   + + G AA+ S  +L   A       +AP  +AP+  PA  S++         
Sbjct: 1413 KKAPATPVTREG-AATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSK--------- 1462

Query: 121  LWQSYCGYLTWHSGLAAFPAYCSPQP-------------SPQSFPSG----GAAVPQAAA 163
                         G    PA   P P             SP+  P+     GA    A  
Sbjct: 1463 -------------GDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVI 1509

Query: 164  PPPPQLGYYNPFYFLSPGAAGPDPRTAAGISTPAPVAGLGPRAPHVQASVR--------- 214
            P  P+     P     P A      +    +T AP   L P A  V +  +         
Sbjct: 1510 PSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKE 1569

Query: 215  --ATPVTRVGSAAPSRSPSE-TGRQAGREYVIP 244
              ATP ++  S+ P+ +PS   G  + +E +IP
Sbjct: 1570 APATPSSKEASSPPAVTPSTYKGAPSPKELLIP 1602



 Score = 35.8 bits (81), Expect = 0.073
 Identities = 57/229 (24%), Positives = 76/229 (33%), Gaps = 28/229 (12%)

Query: 19   GGDHEPVPSLRGPPTTAVPCPRDDPQAEPQAPGRPTAPGLAAAAAADKLEPPRELRKRGE 78
            GG   P P     P  A P       A P   G PT P     +    L  P     +G 
Sbjct: 1092 GGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATP---PPKGA 1148

Query: 79   AASGSGAELQEQAGCEAPEAAAPRERPARLSAREYSRQVHEWLWQSYCGYLTWHSGLAAF 138
              + +      + G   P    P+  P   +A   S +          G L   S   A 
Sbjct: 1149 PTTPAATPPSPKGGLATP---PPKGAPTTPAATPPSPK----------GGLATPSPKGAP 1195

Query: 139  PAYCSPQPSPQ---SFPS-GGAAVPQAAAPPPPQLGYYNPF---YFLSPGAAGPDPRTAA 191
                +  PSP+   + PS  GA    AA PP P+ G   P       +P A  P P+   
Sbjct: 1196 TTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPK--G 1253

Query: 192  GISTPAPVAGLGPRA---PHVQASVRATPVTRVGSAAPSRSPSETGRQA 237
            G +TP P     P A   P ++  +   P     + A    PS  G  A
Sbjct: 1254 GPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPA 1302



 Score = 28.9 bits (63), Expect = 8.9
 Identities = 53/237 (22%), Positives = 72/237 (30%), Gaps = 36/237 (15%)

Query: 12   PPGQDDGGGDHEPVPSLRGPPTT----AVPCPRDDPQAEPQAPGRPTAPGLAAAAAADKL 67
            PP          P P    PP+     A P P+  P + P  P        + A+   K+
Sbjct: 1602 PPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKM 1661

Query: 68   EPPRELRKRGEAASGSGAELQEQAGCEAPEAAAPRERPARLSAREYSRQVHEWLWQSYCG 127
                    +G  A      L+E     APE+      P R   +                
Sbjct: 1662 GATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQT--------------- 1706

Query: 128  YLTWHSGLAAFPAYCSPQPSPQSFPSGGAAVPQAAAPPPPQLGYYNPFYFLSPG------ 181
                    A  P  C P PS ++    G+  P +   P P L         + G      
Sbjct: 1707 ----KKSSATSPPIC-PDPSAKN----GSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHS 1757

Query: 182  AAGPDPRTAAGISTPAPVAGLGPRAPHVQ-ASVRATPVTRVG-SAAPSRSPSETGRQ 236
              GP     +  STP   A      P  + ASV A P   V    APS  P+   +Q
Sbjct: 1758 PKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQ 1814


>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
          Length = 1427

 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 56/234 (23%), Positives = 70/234 (29%), Gaps = 44/234 (18%)

Query: 11   HPPGQDDGGGDHEPVPSLRGPPTTAVPCPRD--DPQAEPQAPGRPTAPGLAAAAAADKLE 68
            H P + D        P     P  AVP P +   P A    P  PT+P  A     +   
Sbjct: 982  HAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTS 1041

Query: 69   PPRELRKRGEAASGSGAELQEQAGCEAPEAAAPRERPARLSAREYSRQVHEWLWQSYCGY 128
            P   +    E  S + A    +       A    E P                       
Sbjct: 1042 PAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTS--------------------- 1080

Query: 129  LTWHSGLAAFPAYCSPQPSPQSFPSGGAAVPQAAAPPPPQLGYYNPFYFLSPGAAGPDPR 188
                      PA   P P   + P+  AAVP    P  P      P    SP AA P P 
Sbjct: 1081 ----------PAAAVPTPEEPTSPA--AAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPE 1128

Query: 189  ----TAAGISTPAPVAGLGPRAPHVQASVRA-----TPVTRVGSAAPSRSPSET 233
                 AA + TP   A   P  P  + S  A     TP      AA   +P+E+
Sbjct: 1129 EPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAES 1182



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 63/244 (25%), Positives = 80/244 (32%), Gaps = 28/244 (11%)

Query: 3    EGPEEARGHPPGQDDGGGDHEPVPSLRGPPTTAVPCPRDDPQAEPQAPGRPTAPGLAAAA 62
            E P       P  ++       VP+     + AV  P  +  A P A     A   + AA
Sbjct: 1128 EEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAA 1187

Query: 63   AADKLEPPRELRKRGEAASGSGAELQEQAGCEAPEAAAPR-ERPARLSAREYSRQVHEWL 121
                LE P          +   A L+E     +P A+ P  E PA L+A   + +     
Sbjct: 1188 VVATLEEPTSPAASVPTPAAMVATLEEFT---SPAASVPTSEEPASLAAAVSNPEEPT-- 1242

Query: 122  WQSYCGYLTWHSGLAAFPAYCSPQPS------PQSFPSGGAAVPQAAAPPPPQLGYYNPF 175
                       S  AA P    P  S      P+   S  A+VP    P  P     N  
Sbjct: 1243 -----------SPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLE 1291

Query: 176  YFLSPGAAGPDPRTAA--GISTPAPVAGLGPRA---PHVQASVRATPVTRVGSAAPSRSP 230
               SP AA P P  AA    S P P     P A   P  + S    P   V +   S   
Sbjct: 1292 EPASPAAAVPTPEVAAIPAASVPTPEVPAIPAAAVPPMEEVSPIGVPFLGVSAHTDSVPI 1351

Query: 231  SETG 234
            SE G
Sbjct: 1352 SEEG 1355



 Score = 36.6 bits (83), Expect = 0.043
 Identities = 32/101 (31%), Positives = 39/101 (38%), Gaps = 9/101 (8%)

Query: 146  PSPQSFPSGGAAVPQAAAPPPPQLGYYNPFYFLSPGAAGPDPR----TAAGISTP----A 197
            P+P+   S  AAVP    P  P      P    SP AA P P      AA + TP    +
Sbjct: 1021 PTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTS 1080

Query: 198  PVAGL-GPRAPHVQASVRATPVTRVGSAAPSRSPSETGRQA 237
            P A +  P  P   A+   TP      AA   +P E    A
Sbjct: 1081 PAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPA 1121


>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
           subunit [Homo sapiens]
          Length = 551

 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 31/90 (34%), Positives = 33/90 (36%), Gaps = 5/90 (5%)

Query: 144 PQPSPQSFPSGGAAVPQAAAPPPPQLGYYNPFYFLSPGAAGPDPRTAAGISTPAPVAGLG 203
           P P P   P  G   PQ   PPPP      PF    PG  GP    A     P P  G  
Sbjct: 297 PPPVPGYGPPPGPPPPQQGPPPPP-----GPFPPRPPGPLGPPLTLAPPPHLPGPPPGAP 351

Query: 204 PRAPHVQASVRATPVTRVGSAAPSRSPSET 233
           P APHV  +    P       + SR P  T
Sbjct: 352 PPAPHVNPAFFPPPTNSGMPTSDSRGPPPT 381



 Score = 31.6 bits (70), Expect = 1.4
 Identities = 23/64 (35%), Positives = 25/64 (39%), Gaps = 15/64 (23%)

Query: 138 FPAYCSPQPSPQSFPSGGAAVPQAAAPPPPQLGYYNPFYFLSPGAAGPDPRTAAGISTPA 197
           FP    P   P  FP+G         PP P LG   P     PG  GP P    G   P 
Sbjct: 217 FPGPAGPGGPPPPFPAG-------QTPPRPPLGPPGP-----PGPPGPPP---PGQVLPP 261

Query: 198 PVAG 201
           P+AG
Sbjct: 262 PLAG 265


>gi|14249622 ajuba isoform 1 [Homo sapiens]
          Length = 538

 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 63/271 (23%), Positives = 91/271 (33%), Gaps = 47/271 (17%)

Query: 4   GPEEARGHP------PGQDDGGGDHE-------PVPSLRG------PPTTAVPCPRDDP- 43
           GP  A G P      P ++ G  D E         P   G      PPT A+P P+  P 
Sbjct: 48  GPRGATGGPGDEPLEPAREQGSLDAERNQRGSFEAPRYEGSFPAGPPPTRALPLPQSLPP 107

Query: 44  --QAEPQAPGRPTAPGLAAAAAADKLEPPRELRKRGEAASGSGAELQEQAGCEAPEAAAP 101
             + EP AP        A+++A+D  +P          +S  G+ L + AG      + P
Sbjct: 108 DFRLEPTAPALSPRSSFASSSASDASKP----------SSPRGSLLLDGAGAGGAGGSRP 157

Query: 102 RERPARLSAREYSRQVHEWLWQSYCGYLTWHSGLAAFPAYCSPQPSPQSFPSGGAAVPQA 161
                   +  Y ++    L    C    +   LA  PA  SP   P ++P   AA+ + 
Sbjct: 158 CSNRTSGISMGYDQRHGSPLPAGPC---LFGPPLAGAPAGYSPGGVPSAYPELHAALDRL 214

Query: 162 AAPPPPQLGYYNPFYFLSPGAAGPDPRTAAGISTPAP------------VAGLGPRAPHV 209
            A  P   G     +   P    P     AG+    P            V G G  A   
Sbjct: 215 YAQRPAGFGCQESRHSYPPALGSPGALAGAGVGAAGPLERRGAQPGRHSVTGYGDCAVGA 274

Query: 210 QASVRATPVTRVGSAAPSRSPSETGRQAGRE 240
           +     T + R+      R     G  +G E
Sbjct: 275 RYQDELTALLRLTVGTGGREAGARGEPSGIE 305


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 45.8 bits (107), Expect = 7e-05
 Identities = 69/257 (26%), Positives = 87/257 (33%), Gaps = 60/257 (23%)

Query: 18  GGGDHEPVPSLRGPPTTAVPCP-RDDPQAE--PQAPGRPTAPGLAAAAAADKLEPPRELR 74
           GGG   P         T +  P R  P A   P+AP  P+ P      A   L PP+   
Sbjct: 231 GGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQA---LRPPQVTP 287

Query: 75  KRGEAASGSGAELQEQAGCEAPEAAAPRERPARLSAREYSRQVHEWLWQSYCGYLTWHSG 134
            R +AA   G          +P AA   + P  L A  +S  +        C   T    
Sbjct: 288 PRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSL-------TCQLAT---P 337

Query: 135 LAAFPAYCSPQPSPQSFPSGGAAVPQAA------------------------APPPPQLG 170
           L   P   S  PS Q+ PS  A  P  A                        A PPPQ  
Sbjct: 338 LPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQA- 396

Query: 171 YYNPFYFLSPGAAGPDPRTAAGIS---TPAPVAGLG------------PRAPHVQA--SV 213
              P   L P  A P P  +  +S   TP+P A               P +P VQA  S 
Sbjct: 397 --PPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSP 454

Query: 214 RATPVTRVGSAAPSRSP 230
            A+P     +  PS++P
Sbjct: 455 PASPPVSPSATPPSQAP 471



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 53/202 (26%), Positives = 69/202 (34%), Gaps = 26/202 (12%)

Query: 34  TAVPCPRDDPQAEPQAPGRPTAPGLAAAAAADKLEPPRELRKRGEAASGSGAELQEQAGC 93
           T V  PR  P A P+ P       +++A+     EP    R+R  A  G    LQ  A  
Sbjct: 185 TEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGG----LQRPASR 240

Query: 94  EAPEAAAPRERPARL--SAREYSR------QVHEWLWQSYCGYLTWHSGLAAFPAYCSPQ 145
               +A P   PAR   SAR   R      Q      Q+            A PA     
Sbjct: 241 SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLS 300

Query: 146 PSPQSFPSGGAAVPQAAAPPPPQLGYYNPFYFLSPGAAGPDPRTAAGISTPAPVAGLGPR 205
            SP + PS  AA+   A P  P              A          ++TP P+A   P 
Sbjct: 301 SSPLATPSPSAALQSQAPPTLP--------------ATPHSSSLTCQLATPLPLAPPSPS 346

Query: 206 APHVQASVRATPVTRVGSAAPS 227
           AP    ++ + P T    A  S
Sbjct: 347 APPSLQTLPSPPATPPSQATTS 368



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 58/231 (25%), Positives = 69/231 (29%), Gaps = 57/231 (24%)

Query: 3   EGPEEARGHPPGQDDGGGDHEPVPSLRGPPTTAVPCPRDDPQAEPQAPGRPTAPGLAAAA 62
           + P      PP         +  PSL  PP    P P   P   P A   P AP   AA 
Sbjct: 449 QAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAA- 507

Query: 63  AADKLEPPRELRKRGEAASGSGAELQEQAGCEAPEAAAPRERPARLSAREYSRQVHEWLW 122
                 PP +L K    A  + A    QA   +P A+ P + P                 
Sbjct: 508 ------PPLQLAKPPPQAPPALATPPLQA-LPSPPASFPGQAP----------------- 543

Query: 123 QSYCGYLTWHSGLAAFPAYCSPQPSPQSFPSGGAAVPQAAAPPPPQLGYYNPFYFLSPGA 182
                     S  A+ P      P PQ+ P   A + Q    PP       P     P  
Sbjct: 544 ---------FSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAP---RRPPT 591

Query: 183 AGPDPRTAAGISTPAPVAGLGPRAPHVQASVRATPVTRVGSAAPSRSPSET 233
            GPD      +S P     L P  P                  PSRSPS T
Sbjct: 592 PGPD----TSVSGPRLTLALAPGPP----------------PPPSRSPSST 622



 Score = 37.7 bits (86), Expect = 0.019
 Identities = 63/253 (24%), Positives = 80/253 (31%), Gaps = 73/253 (28%)

Query: 1   MAEGPEEARGHPPGQDDGGGDHEPVPSL----------RGPPTTAVPCPR--DDPQAEP- 47
           +A  P +A   PP    G     P  SL          + PP  A P  +    P A P 
Sbjct: 523 LATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPT 582

Query: 48  -QAPGRPTAPGLAAAAAADKLE-------PPRELRKRGEAASGSGAELQEQAGCEAPE-- 97
            QAP RP  PG   + +  +L        PP   R      SG        +    PE  
Sbjct: 583 LQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEEL 642

Query: 98  ----------AAAPRERPARLSAREYSRQVHEWLWQSYCGYLTWHSG----LAAFPAYCS 143
                     AAA     A L+A               C    W  G    LA   A  +
Sbjct: 643 RGYDSGPEGGAAASPPPDAELAA---------------CHPAAWSRGPAPPLAFRGAPGA 687

Query: 144 PQPSPQSFPSGGA---------AVPQAAAPPPPQLGYYNPFYFLSPGAAGPDPRTAAGIS 194
           P P P +   G A           P++A P P   G  +P         GP P T+ G +
Sbjct: 688 PLPWPPATGPGSADGLCTIYETEGPESATPAP---GALDP---------GPSPGTSGGKA 735

Query: 195 TPAPVAGLGPRAP 207
                AG   R+P
Sbjct: 736 AAGAGAGASSRSP 748


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 45.4 bits (106), Expect = 9e-05
 Identities = 58/217 (26%), Positives = 76/217 (35%), Gaps = 53/217 (24%)

Query: 34  TAVPCPRDDPQAEPQAPGRPTAPGLAAAAAADKLEPPRELRKRGEAASGSGAELQEQAGC 93
           T V  PR  P A P+ P       +++A+     EP    R+R  A  G    LQ  A  
Sbjct: 185 TEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGG----LQRPASR 240

Query: 94  EAPEAAAPRERPARL--SAREYSRQVHEWLWQSYCGYLTWHSGLAAFPAYCSPQPSPQSF 151
               +A P   PAR   SAR                      G    PA+ S QP P+  
Sbjct: 241 SLSSSATPLSSPARSGPSAR----------------------GTPRAPAHPS-QPKPKGL 277

Query: 152 PSGGAAVPQAAAPP----PPQLGYYNPFYFLSPGAAG------PDPRTAA---------- 191
               A  P    PP     P LG  +     +P  +G      P P  AA          
Sbjct: 278 Q---ALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPS 334

Query: 192 -GISTPAPVAGLGPRAPHVQASVRATPVTRVGSAAPS 227
             ++TP P+A   P AP    ++ + P T    A PS
Sbjct: 335 PPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPS 371



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 57/238 (23%), Positives = 71/238 (29%), Gaps = 27/238 (11%)

Query: 3   EGPEEARGHPPGQDDGGGDHEPVPSLRGPPTTAVPCPRDDPQAEPQAPGRPTAPGLAAAA 62
           + P      PP         +  PSL  PP    P P   P   P A   P AP      
Sbjct: 674 QAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP---PPL 730

Query: 63  AADKLEPPRELRKRGEAASGSGAELQEQAGCEAPEAAAPRERPARLSAREYSRQVHEWLW 122
           AA  L+ P         +  +    +      AP    P   PA L     ++   +   
Sbjct: 731 AAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQ--- 787

Query: 123 QSYCGYLTWHSGLAAFPAYCSPQPSPQSFPSGGAAVPQAAAP------PPPQLGYYNPFY 176
                       LA  P    P P P SFP      P A+ P      PPPQ        
Sbjct: 788 --------APPALATPPLQALPSP-PASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAP 838

Query: 177 FLS-PGAAGPDPRTAAGISTPAPVAGLGPRAPHVQASVRATPVTRVGSAAPSRSPSET 233
            L  P +    P   A    P P        P +  ++   P        PSRSPS T
Sbjct: 839 LLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGP-----PPPPSRSPSST 891



 Score = 37.7 bits (86), Expect = 0.019
 Identities = 63/253 (24%), Positives = 80/253 (31%), Gaps = 73/253 (28%)

Query: 1    MAEGPEEARGHPPGQDDGGGDHEPVPSL----------RGPPTTAVPCPR--DDPQAEP- 47
            +A  P +A   PP    G     P  SL          + PP  A P  +    P A P 
Sbjct: 792  LATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPT 851

Query: 48   -QAPGRPTAPGLAAAAAADKLE-------PPRELRKRGEAASGSGAELQEQAGCEAPE-- 97
             QAP RP  PG   + +  +L        PP   R      SG        +    PE  
Sbjct: 852  LQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEEL 911

Query: 98   ----------AAAPRERPARLSAREYSRQVHEWLWQSYCGYLTWHSG----LAAFPAYCS 143
                      AAA     A L+A               C    W  G    LA   A  +
Sbjct: 912  RGYDSGPEGGAAASPPPDAELAA---------------CHPAAWSRGPAPPLAFRGAPGA 956

Query: 144  PQPSPQSFPSGGA---------AVPQAAAPPPPQLGYYNPFYFLSPGAAGPDPRTAAGIS 194
            P P P +   G A           P++A P P   G  +P         GP P T+ G +
Sbjct: 957  PLPWPPATGPGSADGLCTIYETEGPESATPAP---GALDP---------GPSPGTSGGKA 1004

Query: 195  TPAPVAGLGPRAP 207
                 AG   R+P
Sbjct: 1005 AAGAGAGASSRSP 1017



 Score = 34.7 bits (78), Expect = 0.16
 Identities = 60/216 (27%), Positives = 76/216 (35%), Gaps = 37/216 (17%)

Query: 26  PSLRGPPTTAVPCPRDDPQA--EPQAPGRPTAPGLAAAAAADKLEPPRELRKRGEAASGS 83
           P+L  PP   +P P   P A   PQAP     P L A  +     P   L      A  +
Sbjct: 596 PALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNA 655

Query: 84  GAELQEQAGCEAPEA-------AAPRERPARLSAREYSRQVHEWLWQSYCGYLTWHSGLA 136
            A    QA    P +       + P   P   SA   S+                   LA
Sbjct: 656 LAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQA---------------PPSLA 700

Query: 137 AFPAYCSPQPSPQSFPSGGAAVPQAAAPPP---PQLGYYNPFYFLSP---GAAGPDPRTA 190
           A P    P P P S P   +A P   APPP   P L    P    SP    +A P PR  
Sbjct: 701 APPLQVPPSP-PASPPMSPSATPPPQAPPPLAAPPL-QVPPSPPASPPMSPSATPPPRVP 758

Query: 191 AGISTPAPVAGLGPRAPHVQASVRATPVTRVGSAAP 226
             ++  AP   + P  P   AS+  +P+ +    AP
Sbjct: 759 PLLA--APPLQVPPSPP---ASLPMSPLAKPPPQAP 789



 Score = 33.1 bits (74), Expect = 0.47
 Identities = 49/212 (23%), Positives = 68/212 (32%), Gaps = 28/212 (13%)

Query: 18  GGGDHEPVPSLRGPPTTAVPCP-RDDPQAE--PQAPGRPTAPGLAAAAAADKLEPPRELR 74
           GGG   P         T +  P R  P A   P+AP  P+ P      A   L PP+   
Sbjct: 231 GGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQA---LRPPQVTP 287

Query: 75  KRGEAASGSGAELQEQAGCEAPEAAAPRERPARLSAREYSRQVHEWLWQSYCGYLTWHSG 134
            R +AA   G          +P     R  P   +A                      + 
Sbjct: 288 PRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAAT-----------------PLPAT 330

Query: 135 LAAFPAYCSPQPSPQSFPSGGAAVPQAAAPPPPQLGYYNPFYFLSPGAAGPDPRTAAGIS 194
           L   P   +P P     PS   ++    +PP        P     P  A P  +T   I 
Sbjct: 331 LPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQ 390

Query: 195 TPAPVAG---LGPRAPHVQASVRATPVTRVGS 223
            P  +       P +P   +S++AT  T +GS
Sbjct: 391 VPHSLTSPSLQAPPSPLALSSLQAT--TSLGS 420



 Score = 30.0 bits (66), Expect = 4.0
 Identities = 22/73 (30%), Positives = 28/73 (38%), Gaps = 4/73 (5%)

Query: 139 PAYCSPQPSPQSFPSGGAAVPQAAAPPPPQLGYYNPFYFLSPGAAGPDPRTAAGISTPAP 198
           PA C  Q  P    +     P + A PPPQ     P    SP   G      + ++TP P
Sbjct: 564 PAPCPLQAPPSPLTTPPPETPSSIATPPPQA----PPALASPPLQGLPSPPLSPLATPPP 619

Query: 199 VAGLGPRAPHVQA 211
            A      P +QA
Sbjct: 620 QAPPXLALPPLQA 632


>gi|241982780 programmed cell death 6 interacting protein isoform 2
           [Homo sapiens]
          Length = 873

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 45/161 (27%), Positives = 52/161 (32%), Gaps = 20/161 (12%)

Query: 12  PPGQDDGGGDHEPVPSLRGPPTTAVPCPRDDPQAEPQAPGRPTAPGLAAAAAADKLEPPR 71
           P  Q    G H P P     PT   P PR  P  +PQ P RP  P L A  A     P  
Sbjct: 730 PAYQSSPAGGHAPTP-----PT---PAPRTMPPTKPQPPARPPPPVLPANRAPSATAP-- 779

Query: 72  ELRKRGEAASGSGAELQEQAGCEAPEAAAPRERPARLSAREYSRQVHEWLWQSYCGYLTW 131
                    +G+ A    Q    AP   A  + P   +   Y       +   Y  Y   
Sbjct: 780 -----SPVGAGTAAPAPSQTPGSAPPPQA--QGPPYPTYPGYPGYCQMPMPMGYNPYAYG 832

Query: 132 HSGLAAFPAYCSPQPSPQSFPSGGAAVPQAAAPPPPQLGYY 172
              +   P Y     SP   P  G   P    P PPQ  YY
Sbjct: 833 QYNMPYPPVY---HQSPGQAPYPGPQQPSYPFPQPPQQSYY 870


>gi|22027538 programmed cell death 6 interacting protein isoform 1
           [Homo sapiens]
          Length = 868

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 45/161 (27%), Positives = 52/161 (32%), Gaps = 20/161 (12%)

Query: 12  PPGQDDGGGDHEPVPSLRGPPTTAVPCPRDDPQAEPQAPGRPTAPGLAAAAAADKLEPPR 71
           P  Q    G H P P     PT   P PR  P  +PQ P RP  P L A  A     P  
Sbjct: 725 PAYQSSPAGGHAPTP-----PT---PAPRTMPPTKPQPPARPPPPVLPANRAPSATAP-- 774

Query: 72  ELRKRGEAASGSGAELQEQAGCEAPEAAAPRERPARLSAREYSRQVHEWLWQSYCGYLTW 131
                    +G+ A    Q    AP   A  + P   +   Y       +   Y  Y   
Sbjct: 775 -----SPVGAGTAAPAPSQTPGSAPPPQA--QGPPYPTYPGYPGYCQMPMPMGYNPYAYG 827

Query: 132 HSGLAAFPAYCSPQPSPQSFPSGGAAVPQAAAPPPPQLGYY 172
              +   P Y     SP   P  G   P    P PPQ  YY
Sbjct: 828 QYNMPYPPVY---HQSPGQAPYPGPQQPSYPFPQPPQQSYY 865


>gi|239754516 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 334

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 59/217 (27%), Positives = 77/217 (35%), Gaps = 40/217 (18%)

Query: 28  LRGPPTTAVPCPRDDPQAEPQAPGRPTAPGLAAAAAADK---LEPPRELRKRGEAASGS- 83
           L G  T  V C       + +  GR  APG  A    +K      PR    RG    G  
Sbjct: 14  LCGSDTAGVTCRVSSQDGDRRGLGREAAPGAPAEGEKEKGKNSRRPRPTCSRGRTERGRV 73

Query: 84  --GAELQEQAGCEAPEAAAPRERPARLSAREYSRQVHEWLWQSYCGYLTWHSGLAAFPAY 141
             GA+ QE+       A AP  RP   +A      VH  L                  A 
Sbjct: 74  ERGADHQERP------AGAPAHRPVPAAAAILRAAVHRVL--------------RVLRAA 113

Query: 142 CSPQPSPQSFPSGGAAVPQAAAPPPPQLGYYNPFYFLSPGAAGPDPRTAAGISTPAPVAG 201
            + + + +     G   P+  APP  QL           G  G     +AG     P  G
Sbjct: 114 AAVRDAERGLRREG---PRRHAPPRKQLR----------GRRGAAGLVSAGHLGREPPRG 160

Query: 202 LGPRAPHVQASVRATPVTRVGSAAPS-RSPSETGRQA 237
            GPR P +     ATP+   G + PS R+ + +GRQA
Sbjct: 161 GGPRPPALVPVPLATPLLLEGRSEPSTRACAVSGRQA 197


>gi|206597556 kelch domain containing 7B [Homo sapiens]
          Length = 594

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 36/108 (33%), Positives = 51/108 (47%), Gaps = 9/108 (8%)

Query: 4   GPEEARGHPP---GQDDGGGDHEPVPSLRGPPTTAVPCPRDDPQAEPQAPGRPTA---PG 57
           G  EA G P     + +G    +P P LRG  T           A P+ P +P A   PG
Sbjct: 55  GLVEAGGQPQPRSSETNGSPSPDPPPGLRGEGTREKSLDPLPQAAMPRGPAQPPAQRPPG 114

Query: 58  LAAAAAADKLEPPRELRKRG--EAASGSGAELQEQAGCEAPEAAAPRE 103
            AA+++A + +P  +LRKR   E A  S  E++  A  + P+  AP E
Sbjct: 115 PAASSSARRSQPVPQLRKRSRCEIAPSSEQEVRPAASGD-PQGEAPGE 161


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 62/239 (25%), Positives = 80/239 (33%), Gaps = 39/239 (16%)

Query: 4   GPEEARGHP--PG-QDDGGGDHEPVP-SLRGPPTTAVPCPRDDPQAEPQAPGRPTAPGLA 59
           GP+   G P  PG + D G   EP P  ++GPP  A    +   + EP   G P  PG  
Sbjct: 428 GPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPG-- 485

Query: 60  AAAAADKLEPPRELRKRGEAASGSGAELQEQAGCEAP--EAAAPRERPARLSAREYSRQV 117
                          +RG   S         AG + P  E  +P     + S  E  R  
Sbjct: 486 ---------------ERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPG 530

Query: 118 HEWLWQSYCGYLTWHSGLAAFPAYCSPQPSPQSFPSGGAAVPQAAAPPPPQ--LGYYNPF 175
              L  +         GL   P   SP P  ++ P G A       PP P    G     
Sbjct: 531 EAGLPGA--------KGLTGSPG--SPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVM 580

Query: 176 YFLSPGAAGPDPRTAAGISTPAPVAGLGPRAPHVQASVRATPVTRVGSAAPSRSPSETG 234
            F  P  A  +P  A     P P   +GP     +A  +  P    G A P+    E G
Sbjct: 581 GFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPP----GPAGPAGERGEQG 635



 Score = 36.2 bits (82), Expect = 0.056
 Identities = 56/242 (23%), Positives = 69/242 (28%), Gaps = 30/242 (12%)

Query: 4    GPEEARGHPPGQD--DGGGDHEPVPSLRGPPTTAVPCPRDDPQAEPQAPGRPTAPGLAAA 61
            GP    G PPG+   +G    E  P   G P          P   P APG P APG    
Sbjct: 1001 GPPGLAG-PPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPG---- 1055

Query: 62   AAADKLEPPRELRKRGEAASGSGAELQEQAGCEAPEAAAPRERPARLSAREYSRQVHEWL 121
                 + P  +   RGE      A      G   P            +  +  R +    
Sbjct: 1056 ----PVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGI---- 1107

Query: 122  WQSYCGYLTWHSGLAAFPAYCSPQPSPQSFPSGGAAVPQAAAPPPPQLGYYNPFYFLS-P 180
                      H G +       P  SP      GA+ P     PP   G          P
Sbjct: 1108 --------KGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLP 1159

Query: 181  GAAG-PDPRTAAGISTPAPVAGLGPRAPHVQASVRATPVTRVGSAAPSRSPSETGRQAGR 239
            G  G P PR   G + P     +GP  P         P      +   + P E     GR
Sbjct: 1160 GPIGPPGPRGRTGDAGP-----VGPPGPPGPPGPPGPPSAGFDFSFLPQPPQEKAHDGGR 1214

Query: 240  EY 241
             Y
Sbjct: 1215 YY 1216



 Score = 31.6 bits (70), Expect = 1.4
 Identities = 65/248 (26%), Positives = 77/248 (31%), Gaps = 57/248 (22%)

Query: 12  PPGQDDGGGDH-EPVPSLRGPPTTAVPCPRDDPQAEPQAPGRPTAPGLAAAAAADKLEPP 70
           PPG     GD  E  PS    PT A   P D  +     PG P   G A    AD    P
Sbjct: 771 PPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGE-----PGPPGPAGFAGPPGAD--GQP 823

Query: 71  RELRKRGEAASGSGAELQEQAGCEAP-----EAAAPRERPARLSAREYSRQVHEWLWQSY 125
               + G+A +   A     AG   P        AP  + AR SA               
Sbjct: 824 GAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGP------------- 870

Query: 126 CGYLTWHSGLAAFPAYCS----PQPSPQSFPSG--------GAAVPQAAAPPPPQLGYYN 173
                   G   FP        P PS  + P G        G   P+    P  + G   
Sbjct: 871 -------PGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVG 923

Query: 174 PFYFLSPGAAGP-DPRTAAGISTPAPVAGL-GPRAPHVQASVRATPVTR-----VGSAAP 226
           P     PG  GP   + + G   PA   G  GP+    Q  V   P  R      G   P
Sbjct: 924 P-----PGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGP 978

Query: 227 SRSPSETG 234
           S  P + G
Sbjct: 979 SGEPGKQG 986


>gi|116734706 interferon regulatory factor 2 binding protein 2
           isoform B [Homo sapiens]
          Length = 571

 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 56/195 (28%), Positives = 78/195 (40%), Gaps = 48/195 (24%)

Query: 50  PGRPTAPGLAAAAAADKLEPP----RELRKRGEAASGSGAELQEQAGCEAPEA------A 99
           P   + PG AA+AAA   +PP    +++  + +   G G     +A   AP+A      A
Sbjct: 67  PEGRSPPGAAASAAA---KPPPLSAKDILLQQQQQLGHGGP---EAAPRAPQALERYPLA 120

Query: 100 APRERPARLSAREYSRQVHEWLWQSYCGYLTWHSGLAAFPAYCSPQPSPQSFPSGGAAVP 159
           A  ERP RL +                       G +   A  +  P+PQ  P  G  VP
Sbjct: 121 AAAERPPRLGS---------------------DFGSSRPAASLAQPPTPQPPPVNGILVP 159

Query: 160 QAAAP--PPPQLGYYNPFYFLSPGAAGPDPRTAA----GISTPAPVA-GLGPRAPHVQAS 212
              +    PP+L   +P    +P      P T      G +TP P A GLG RA    A+
Sbjct: 160 NGFSKLEEPPELNRQSP----NPRRGHAVPPTLVPLMNGSATPLPTALGLGGRAAASLAA 215

Query: 213 VRATPVTRVGSAAPS 227
           V  T    +GSA P+
Sbjct: 216 VSGTAAASLGSAQPT 230


>gi|116734704 interferon regulatory factor 2 binding protein 2
           isoform A [Homo sapiens]
          Length = 587

 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 56/195 (28%), Positives = 78/195 (40%), Gaps = 48/195 (24%)

Query: 50  PGRPTAPGLAAAAAADKLEPP----RELRKRGEAASGSGAELQEQAGCEAPEA------A 99
           P   + PG AA+AAA   +PP    +++  + +   G G     +A   AP+A      A
Sbjct: 67  PEGRSPPGAAASAAA---KPPPLSAKDILLQQQQQLGHGGP---EAAPRAPQALERYPLA 120

Query: 100 APRERPARLSAREYSRQVHEWLWQSYCGYLTWHSGLAAFPAYCSPQPSPQSFPSGGAAVP 159
           A  ERP RL +                       G +   A  +  P+PQ  P  G  VP
Sbjct: 121 AAAERPPRLGS---------------------DFGSSRPAASLAQPPTPQPPPVNGILVP 159

Query: 160 QAAAP--PPPQLGYYNPFYFLSPGAAGPDPRTAA----GISTPAPVA-GLGPRAPHVQAS 212
              +    PP+L   +P    +P      P T      G +TP P A GLG RA    A+
Sbjct: 160 NGFSKLEEPPELNRQSP----NPRRGHAVPPTLVPLMNGSATPLPTALGLGGRAAASLAA 215

Query: 213 VRATPVTRVGSAAPS 227
           V  T    +GSA P+
Sbjct: 216 VSGTAAASLGSAQPT 230


>gi|239754042 PREDICTED: similar to hCG1646049 [Homo sapiens]
          Length = 346

 Score = 42.7 bits (99), Expect = 6e-04
 Identities = 54/186 (29%), Positives = 78/186 (41%), Gaps = 19/186 (10%)

Query: 75  KRGEAASGSGAELQEQAGCEAPEAAAPRERPARLSAREYSRQVHEWLWQSY---CGYLTW 131
           KR    +G+ +E + QA   AP    PRER    S R  + +      +      G    
Sbjct: 44  KRSSGQAGNKSERELQARTPAP----PRERGESSSPRGPTLRGRAKTTRGRSQGAGATET 99

Query: 132 HSGLAAFPAYCSPQPSPQSFPSGGAAVPQAAAPPPPQL-GYYNPFYFL----SPGAAGPD 186
            +G +A  A  +P P+P S+P G  + PQ  AP P +  G   P + +    +  A  P+
Sbjct: 100 SAGNSA--ATAAPHPTPASYPQGTISPPQLPAPRPKRFGGKQRPLWRIRGWETTVARLPE 157

Query: 187 PRTA-AGISTPAPVAGLGPR-APHVQAS--VRATPVTRVGSAAP-SRSPSETGRQAGREY 241
           PR    G   P   A  G R  P  +A+  +R       G  AP +R P  T R  GR  
Sbjct: 158 PRVGKLGKGPPPRPAPPGTRCCPGARAAQLLREAAAAAQGLRAPAARLPEPTRRAPGRPG 217

Query: 242 VIPSLA 247
            +P+ A
Sbjct: 218 CLPTAA 223


>gi|239748572 PREDICTED: similar to hCG1646049 [Homo sapiens]
          Length = 346

 Score = 42.7 bits (99), Expect = 6e-04
 Identities = 54/186 (29%), Positives = 78/186 (41%), Gaps = 19/186 (10%)

Query: 75  KRGEAASGSGAELQEQAGCEAPEAAAPRERPARLSAREYSRQVHEWLWQSY---CGYLTW 131
           KR    +G+ +E + QA   AP    PRER    S R  + +      +      G    
Sbjct: 44  KRSSGQAGNKSERELQARTPAP----PRERGESSSPRGPTLRGRAKTTRGRSQGAGATET 99

Query: 132 HSGLAAFPAYCSPQPSPQSFPSGGAAVPQAAAPPPPQL-GYYNPFYFL----SPGAAGPD 186
            +G +A  A  +P P+P S+P G  + PQ  AP P +  G   P + +    +  A  P+
Sbjct: 100 SAGNSA--ATAAPHPTPASYPQGTISPPQLPAPRPKRFGGKQRPLWRIRGWETTVARLPE 157

Query: 187 PRTA-AGISTPAPVAGLGPR-APHVQAS--VRATPVTRVGSAAP-SRSPSETGRQAGREY 241
           PR    G   P   A  G R  P  +A+  +R       G  AP +R P  T R  GR  
Sbjct: 158 PRVGKLGKGPPPRPAPPGTRCCPGARAAQLLREAAAAAQGLRAPAARLPEPTRRAPGRPG 217

Query: 242 VIPSLA 247
            +P+ A
Sbjct: 218 CLPTAA 223


>gi|169167670 PREDICTED: similar to hCG1646049 [Homo sapiens]
          Length = 346

 Score = 42.7 bits (99), Expect = 6e-04
 Identities = 54/186 (29%), Positives = 78/186 (41%), Gaps = 19/186 (10%)

Query: 75  KRGEAASGSGAELQEQAGCEAPEAAAPRERPARLSAREYSRQVHEWLWQSY---CGYLTW 131
           KR    +G+ +E + QA   AP    PRER    S R  + +      +      G    
Sbjct: 44  KRSSGQAGNKSERELQARTPAP----PRERGESSSPRGPTLRGRAKTTRGRSQGAGATET 99

Query: 132 HSGLAAFPAYCSPQPSPQSFPSGGAAVPQAAAPPPPQL-GYYNPFYFL----SPGAAGPD 186
            +G +A  A  +P P+P S+P G  + PQ  AP P +  G   P + +    +  A  P+
Sbjct: 100 SAGNSA--ATAAPHPTPASYPQGTISPPQLPAPRPKRFGGKQRPLWRIRGWETTVARLPE 157

Query: 187 PRTA-AGISTPAPVAGLGPR-APHVQAS--VRATPVTRVGSAAP-SRSPSETGRQAGREY 241
           PR    G   P   A  G R  P  +A+  +R       G  AP +R P  T R  GR  
Sbjct: 158 PRVGKLGKGPPPRPAPPGTRCCPGARAAQLLREAAAAAQGLRAPAARLPEPTRRAPGRPG 217

Query: 242 VIPSLA 247
            +P+ A
Sbjct: 218 CLPTAA 223


>gi|210032580 SET domain containing 1B [Homo sapiens]
          Length = 1923

 Score = 42.7 bits (99), Expect = 6e-04
 Identities = 52/220 (23%), Positives = 71/220 (32%), Gaps = 51/220 (23%)

Query: 12  PPGQDDGGGDHEPVPSLRGPPTTAV------PCPRDDPQAE---------PQAPGRPTAP 56
           P G +   G   P P    P +T +      P P  D   E         P  PG P   
Sbjct: 545 PFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGLGPRPPPEPGPPDPA 604

Query: 57  GLAAAAAADKLE------PPRELRKRGEAASGSGAELQEQAGCEAPEAAAPRERPARLSA 110
           GL +  A   L+      P  E    G+ +SG   E+ +     AP  +A   +P     
Sbjct: 605 GLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPM---- 660

Query: 111 REYSRQVHEWLWQSYCGYLTWHSGLAAFPAYCSPQ---PSPQSFPSGGAAVPQAAAPPPP 167
                             +T  +   A P+  +P    P P  FP     +P    PPPP
Sbjct: 661 -----------------VVTPGAAAVAAPSVLAPTLPLPPPPGFPP----LPPPPPPPPP 699

Query: 168 QLGYYNPFYFLSPGAAGPDPRTAAGISTPAPVAGLGPRAP 207
           Q G+  P     P    P P     ++ P P     P  P
Sbjct: 700 QPGF--PMPPPLPPPPPPPPPAHPAVTVPPPPLPAPPGVP 737


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 42.4 bits (98), Expect = 8e-04
 Identities = 52/199 (26%), Positives = 71/199 (35%), Gaps = 50/199 (25%)

Query: 34  TAVPCPRDDPQAEPQAPGRPTAPGLAAAAAADKLEPPRELRKRGEAASGSGAELQEQAGC 93
           T V  PR  P A P+ P       +++A+     EP    R+R  A  G    LQ  A  
Sbjct: 176 TEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGG----LQRPASR 231

Query: 94  EAPEAAAPRERPARL--SAREYSRQVHEWLWQSYCGYLTWHSGLAAFPAYCSPQPSPQSF 151
               +A P   PAR   SAR                      G    PA+ S QP P+  
Sbjct: 232 SLSSSATPLSSPARSGPSAR----------------------GTPRAPAHPS-QPKPKGL 268

Query: 152 PSGGAAVPQAAAPP---PPQLGYYNPFYFLSPGAAGPDPRTAAGISTPAPVAGLGPRAPH 208
                   QA  PP   PP+             A    P +++ ++TP+P A   P AP 
Sbjct: 269 --------QALRPPQVTPPR----------KDAAPALGPLSSSPLATPSPSAPPSPSAPP 310

Query: 209 VQASVRATPVTRVGSAAPS 227
              ++ + P T    A  S
Sbjct: 311 SLQTLPSPPATPPSQATTS 329



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 62/222 (27%), Positives = 80/222 (36%), Gaps = 20/222 (9%)

Query: 18  GGGDHEPVPSLRGPPTTAVPCP-RDDPQAE--PQAPGRPTAPGLAAAAAADKLEPPRELR 74
           GGG   P         T +  P R  P A   P+AP  P+ P      A   L PP+   
Sbjct: 222 GGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQA---LRPPQVTP 278

Query: 75  KRGEAASGSGAELQEQAGCEAPEAAAPRERPARLSAREYSRQVHEWLWQSYCGYLT---W 131
            R +AA   G          +P A      P  L               +  G  T    
Sbjct: 279 PRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQAT 338

Query: 132 HSGLAAFPAYCSPQPSPQSFPSGGAAVPQAAAPP-PPQLGYYNPFYFLSPGAAGPDPRTA 190
           HS L + P      P PQ+ P+   A+P   APP PP     +P    SP A    P   
Sbjct: 339 HSFLPSPPLSPLATPPPQAPPA--LALPPLQAPPSPPASPPLSPLATPSPQA----PNAL 392

Query: 191 AGISTPAPVAGLGPRAPHVQA--SVRATPVTRVGSAAPSRSP 230
           A     AP +   P +P VQA  S  A+P     +  PS++P
Sbjct: 393 AVHLLQAPFS--PPPSPPVQAPFSPPASPPVSPSATPPSQAP 432



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 58/231 (25%), Positives = 69/231 (29%), Gaps = 57/231 (24%)

Query: 3   EGPEEARGHPPGQDDGGGDHEPVPSLRGPPTTAVPCPRDDPQAEPQAPGRPTAPGLAAAA 62
           + P      PP         +  PSL  PP    P P   P   P A   P AP   AA 
Sbjct: 410 QAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAA- 468

Query: 63  AADKLEPPRELRKRGEAASGSGAELQEQAGCEAPEAAAPRERPARLSAREYSRQVHEWLW 122
                 PP +L K    A  + A    QA   +P A+ P + P                 
Sbjct: 469 ------PPLQLAKPPPQAPPALATPPLQA-LPSPPASFPGQAP----------------- 504

Query: 123 QSYCGYLTWHSGLAAFPAYCSPQPSPQSFPSGGAAVPQAAAPPPPQLGYYNPFYFLSPGA 182
                     S  A+ P      P PQ+ P   A + Q    PP       P     P  
Sbjct: 505 ---------FSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAP---RRPPT 552

Query: 183 AGPDPRTAAGISTPAPVAGLGPRAPHVQASVRATPVTRVGSAAPSRSPSET 233
            GPD      +S P     L P  P                  PSRSPS T
Sbjct: 553 PGPD----TSVSGPRLTLALAPGPP----------------PPPSRSPSST 583



 Score = 38.1 bits (87), Expect = 0.015
 Identities = 53/205 (25%), Positives = 66/205 (32%), Gaps = 43/205 (20%)

Query: 26  PSLRGPPTTAVPCPRDDPQAEPQAPGRPTAP-GLAAAAAADKLEPPRELRKRGEAASGSG 84
           P+L  PP  A P P   P   P A   P AP  LA         PP     +   +  + 
Sbjct: 359 PALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPAS 418

Query: 85  AELQEQAGCEAPEAAAPRERPARLSAREYSRQVHEWLWQSYCGYLTWHSGLAAFPAYCSP 144
             +       +P A  P + P                             LAA P    P
Sbjct: 419 PPV-------SPSATPPSQAP---------------------------PSLAAPPLQVPP 444

Query: 145 QPSPQSFPSGGAAVPQAAAPPP---PQLGYYNPFYFLSPGAAGPDPRTAAGISTPAPVAG 201
            P P S P   +A P   APPP   P L    P     P  A P  +     S PA   G
Sbjct: 445 SP-PASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALP--SPPASFPG 501

Query: 202 LGPRAPHVQASVRATPVTRVGSAAP 226
             P +P   AS+  +P+      AP
Sbjct: 502 QAPFSP--SASLPMSPLATPPPQAP 524



 Score = 37.7 bits (86), Expect = 0.019
 Identities = 63/253 (24%), Positives = 80/253 (31%), Gaps = 73/253 (28%)

Query: 1   MAEGPEEARGHPPGQDDGGGDHEPVPSL----------RGPPTTAVPCPR--DDPQAEP- 47
           +A  P +A   PP    G     P  SL          + PP  A P  +    P A P 
Sbjct: 484 LATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPT 543

Query: 48  -QAPGRPTAPGLAAAAAADKLE-------PPRELRKRGEAASGSGAELQEQAGCEAPE-- 97
            QAP RP  PG   + +  +L        PP   R      SG        +    PE  
Sbjct: 544 LQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEEL 603

Query: 98  ----------AAAPRERPARLSAREYSRQVHEWLWQSYCGYLTWHSG----LAAFPAYCS 143
                     AAA     A L+A               C    W  G    LA   A  +
Sbjct: 604 RGYDSGPEGGAAASPPPDAELAA---------------CHPAAWSRGPAPPLAFRGAPGA 648

Query: 144 PQPSPQSFPSGGA---------AVPQAAAPPPPQLGYYNPFYFLSPGAAGPDPRTAAGIS 194
           P P P +   G A           P++A P P   G  +P         GP P T+ G +
Sbjct: 649 PLPWPPATGPGSADGLCTIYETEGPESATPAP---GALDP---------GPSPGTSGGKA 696

Query: 195 TPAPVAGLGPRAP 207
                AG   R+P
Sbjct: 697 AAGAGAGASSRSP 709


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 42.4 bits (98), Expect = 8e-04
 Identities = 55/212 (25%), Positives = 67/212 (31%), Gaps = 55/212 (25%)

Query: 12  PPGQDDGGGDHEPVPSLRGPPTTAVPCPRDDPQAEPQAP-----------GRPTAPGLAA 60
           PP Q       +  P  + PP    P P+   Q +P  P           G   APG+ +
Sbjct: 64  PPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGS 123

Query: 61  AAAADKLEPPRELRKRGEAASGSG---AELQEQAGCEAPEAAAPRERPARLSAREYSRQV 117
           A  A    PP      G A  GSG         A   AP  A P   P+           
Sbjct: 124 APPASSSAPPATPPTSG-APPGSGPGPTPTPPPAVTSAPPGAPPPTPPS----------- 171

Query: 118 HEWLWQSYCGYLTWHSGLAAFPAYC-SPQPSPQSFPSGGAAVPQAAAPPPPQLGYYNPFY 176
                          SG+   P     P P P + P  G    Q   P  P+ G      
Sbjct: 172 ---------------SGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPKGG------ 210

Query: 177 FLSPGAAGPDPRTAAGISTPAPVAGLGPRAPH 208
              PG  GP P    G+STP    G  P+ PH
Sbjct: 211 -KMPG--GPKPGGGPGLSTP----GGHPKPPH 235



 Score = 29.6 bits (65), Expect = 5.2
 Identities = 26/89 (29%), Positives = 29/89 (32%), Gaps = 19/89 (21%)

Query: 145 QPSPQSFPSGGAAVPQAAAPPPPQLGYYNPFYFLSPGAAGPDPRTAAGISTPAPVAGLGP 204
           QP P   P       Q   PPPPQ                  P  A G   P P  G+G 
Sbjct: 81  QPPPHQPPPHPQPHQQQQPPPPPQ--------------DSSKPVVAQG---PGPAPGVGS 123

Query: 205 RAPHVQASVRATPVTRVGSAAPSRSPSET 233
             P   ++  ATP T    A P   P  T
Sbjct: 124 APPASSSAPPATPPT--SGAPPGSGPGPT 150


>gi|61966741 TMF regulated nuclear protein [Homo sapiens]
          Length = 227

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 38/117 (32%), Positives = 48/117 (41%), Gaps = 23/117 (19%)

Query: 3   EGPEEARGHPPGQDDGGGDHEPVPSLRGPPTTAVPCPRDDPQAEPQAPGRPTAPGLAAAA 62
           EG  E R  PP +D       P+PS + PP T    P   P    Q+P  P A G +A A
Sbjct: 15  EGTAEQRSPPPPRD-------PMPSSQPPPPTPTLTPTPTP---GQSPPLPDAAGASAGA 64

Query: 63  AADKLEPPRELRK--------RGEAASGSGAELQEQAGCEAPEAAAPRERPARLSAR 111
           A D     +EL++         G A  G G+     AG  A E A  R R   +  R
Sbjct: 65  AED-----QELQRWRQGASGIAGLAGPGGGSGAAAGAGGRALELAEARRRLLEVEGR 116


>gi|27894344 nuclear receptor subfamily 4, group A, member 1 [Homo
           sapiens]
          Length = 598

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 54/228 (23%), Positives = 76/228 (33%), Gaps = 66/228 (28%)

Query: 32  PTTAVPCPRDDPQAEPQAPGRPTAPGLAAAAAAD---------KLEPPRELRKRGEAASG 82
           P T  PC      A   +    T+P  A+    D          L  P +     EA S 
Sbjct: 72  PGTVQPCSSASSSASSTSSSSATSPASASFKFEDFQVYGCYPGPLSGPVD-----EALSS 126

Query: 83  SGAELQEQAGCEAPEAAAPRERPARLSAREYSRQVHEWLWQSYCGYLTWHSGLAAFPAYC 142
           SG++      C AP  + P  +P +LS            W    G+              
Sbjct: 127 SGSDYYGSP-CSAPSPSTPSFQPPQLSP-----------WDGSFGHF------------- 161

Query: 143 SPQPSPQSFPSGGAAVPQAAAPPPPQLGYYNPFYFLSPGAAGPDPRTAAG---------- 192
           SP  + +   +    +P+A+ PP P      P +F      GP P  A            
Sbjct: 162 SPSQTYEGLRAWTEQLPKASGPPQP------PAFFSFSPPTGPSPSLAQSPLKLFPSQAT 215

Query: 193 --------ISTPAPVAGLGPRAPHVQAS-VRATPV--TRVGSAAPSRS 229
                    S P    GL P +PH++ S +  TPV  T+  S AP  S
Sbjct: 216 HQLGEGESYSMPTAFPGLAPTSPHLEGSGILDTPVTSTKARSGAPGGS 263


>gi|21361342 nuclear receptor subfamily 4, group A, member 1 [Homo
           sapiens]
          Length = 598

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 54/228 (23%), Positives = 76/228 (33%), Gaps = 66/228 (28%)

Query: 32  PTTAVPCPRDDPQAEPQAPGRPTAPGLAAAAAAD---------KLEPPRELRKRGEAASG 82
           P T  PC      A   +    T+P  A+    D          L  P +     EA S 
Sbjct: 72  PGTVQPCSSASSSASSTSSSSATSPASASFKFEDFQVYGCYPGPLSGPVD-----EALSS 126

Query: 83  SGAELQEQAGCEAPEAAAPRERPARLSAREYSRQVHEWLWQSYCGYLTWHSGLAAFPAYC 142
           SG++      C AP  + P  +P +LS            W    G+              
Sbjct: 127 SGSDYYGSP-CSAPSPSTPSFQPPQLSP-----------WDGSFGHF------------- 161

Query: 143 SPQPSPQSFPSGGAAVPQAAAPPPPQLGYYNPFYFLSPGAAGPDPRTAAG---------- 192
           SP  + +   +    +P+A+ PP P      P +F      GP P  A            
Sbjct: 162 SPSQTYEGLRAWTEQLPKASGPPQP------PAFFSFSPPTGPSPSLAQSPLKLFPSQAT 215

Query: 193 --------ISTPAPVAGLGPRAPHVQAS-VRATPV--TRVGSAAPSRS 229
                    S P    GL P +PH++ S +  TPV  T+  S AP  S
Sbjct: 216 HQLGEGESYSMPTAFPGLAPTSPHLEGSGILDTPVTSTKARSGAPGGS 263


>gi|116268127 kinase non-catalytic C-lobe domain (KIND) containing 1
           isoform a [Homo sapiens]
          Length = 1749

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 31/106 (29%), Positives = 43/106 (40%), Gaps = 12/106 (11%)

Query: 12  PPGQDDGGGDHEPVPSLRGPPTTAVPCPRDDPQAEPQAPG------RPTAPGLAAAAAAD 65
           P  Q +G     P   +  PPT A   P +   AEP  PG      RP A G   A    
Sbjct: 766 PANQPEGASSAAPGSPVPAPPTKASALPVEQGPAEPIPPGVASGGLRPDALGPTTAHHGP 825

Query: 66  KLEPPRELRKR-----GEAASGSGAELQEQAGCEAPEAAAPRERPA 106
           +  PP+  R +     G+   G GA    +   ++P++   R RPA
Sbjct: 826 R-HPPKPPRSKATERPGQEPEGPGATPAGERDDQSPDSVPERPRPA 870



 Score = 30.8 bits (68), Expect = 2.3
 Identities = 57/248 (22%), Positives = 79/248 (31%), Gaps = 40/248 (16%)

Query: 1   MAEGPEEARGHPPGQDDGGGDHEPVPSLRGPPTTAVPCPRDDPQAEPQAPGRPT--APGL 58
           +A  PE + G  P   D G     + ++ GP     PC  +  Q         T   P +
Sbjct: 627 VAPAPEPSPGFLPVNSDTG-----LVAVPGPVPGQHPCGEEATQLPAAFTSEATHFKPIV 681

Query: 59  AAAAAADKLEPP----RELRKRGEAASGSGAE---LQEQAGC---EAPEAAAPRERPARL 108
            A  A+   + P     E  +RG    G G E   L+  AG    + P+   P   P   
Sbjct: 682 LAQNASVARDQPALAQEESEERGGQREGEGEEKLSLEAHAGSPSLKTPDGPVPGPGPQGA 741

Query: 109 SAREYSRQVHEWLWQSYCGYLTWHSGLAAFPAYCSPQPSPQSFPSG-GAAVPQAAAPPPP 167
           +       V     Q                  C P  +P + P G  +A P +  P PP
Sbjct: 742 APEPLGASVQRDSAQG---------------RPCPPPQAPANQPEGASSAAPGSPVPAPP 786

Query: 168 QLGYYNPFYFLSPGAAGP-DPRTAAGISTPAPVAGLGPRAPHVQASVRATPVTRVGSAAP 226
                 P   +  G A P  P  A+G   P     LGP   H        P     +  P
Sbjct: 787 TKASALP---VEQGPAEPIPPGVASGGLRP---DALGPTTAHHGPRHPPKPPRSKATERP 840

Query: 227 SRSPSETG 234
            + P   G
Sbjct: 841 GQEPEGPG 848


>gi|85815829 SH3-domain binding protein 1 [Homo sapiens]
          Length = 701

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 60/207 (28%), Positives = 73/207 (35%), Gaps = 60/207 (28%)

Query: 32  PTTAVPCPRDDPQAEPQAPGRPTAPGLAAAAAADKLE---PPRELRKRGEAASGSGAELQ 88
           P+TAVP P   P   P AP    AP LA+AA  ++ E   PPR    +   +        
Sbjct: 500 PSTAVPTPATTPAPAP-APAPAPAPALASAATKERTESEVPPRPASPKVTRS-------- 550

Query: 89  EQAGCEAPEAAAPRERPARLSAREYSRQVHEWLWQSYCGYLTWHSGLAAFPAYCSP-QPS 147
                  PE AAP E  AR + R                           PA   P  P 
Sbjct: 551 ------PPETAAPVEDMARRTKR---------------------------PAPARPTMPP 577

Query: 148 PQSFPSGGAAVPQAAAPPPPQLGYYNPFYFLSPGAAGPDPRTAAGISTPAPVA--GLGPR 205
           PQ   SG  + P  A P PP  G        SPG     PR   G S  AP     L P 
Sbjct: 578 PQ--VSGSRSSP-PAPPLPPGSG--------SPGTPQALPRRLVGSSLRAPTVPPPLPPT 626

Query: 206 APH-VQASVRATPVTRVGSAAPSRSPS 231
            P   +   R +P +   ++    SPS
Sbjct: 627 PPQPARRQSRRSPASPSPASPGPASPS 653



 Score = 32.7 bits (73), Expect = 0.62
 Identities = 37/142 (26%), Positives = 49/142 (34%), Gaps = 21/142 (14%)

Query: 29  RGPPTTAVPCPRDDPQAEPQAPGRPTAPGLAAAAAADKLEPPRELRKRGEAASGSGAELQ 88
           R PP TA P      + +  AP RPT P      +  +  PP      G  + G+   L 
Sbjct: 549 RSPPETAAPVEDMARRTKRPAPARPTMP--PPQVSGSRSSPPAPPLPPGSGSPGTPQALP 606

Query: 89  EQ---AGCEAPEAAAPRERPARLSAREYSRQVHEWLWQSYCGYLTWHSGLAAFPAYCSPQ 145
            +   +   AP    P        AR  SR+             +  S   A P   SP 
Sbjct: 607 RRLVGSSLRAPTVPPPLPPTPPQPARRQSRR-------------SPASPSPASPGPASPS 653

Query: 146 PSPQSFPSG---GAAVPQAAAP 164
           P   S P+    GAA  +  AP
Sbjct: 654 PVSLSNPAQVDLGAATAEGGAP 675


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 40.4 bits (93), Expect = 0.003
 Identities = 71/251 (28%), Positives = 86/251 (34%), Gaps = 26/251 (10%)

Query: 2   AEGPEEARGHPP--GQDD--GGGDHEP-VPSLRGPPTTAVPCPRDDPQAEPQAPGRPTAP 56
           AEG   A   PP  G+    GGG   P  PS R P   A P P   P A+ + P   +A 
Sbjct: 79  AEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAP---PAAKLRPPPEGSAG 135

Query: 57  GLAAAAAADKLEPPRELRKRGEAASGSGAELQEQAGCEAPEAAAPRERPARLSAREYSRQ 116
             A   AA  +    E    G A     A L  +AG        P   P     +     
Sbjct: 136 SCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPG--PGKPAGPG 193

Query: 117 VHEWLWQSYCGYLTWHSGLAAF------PAYCSPQPSP-------QSFPSGGAAVPQAAA 163
             + L  S     + H+   A       PA   P P P       Q+ P  GAA P A A
Sbjct: 194 AAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPA 253

Query: 164 PPPPQLGYYNPFYFLSPGAAGPDPRTAAGISTPAPVAGLGPRAPHVQASVRATPVTRVGS 223
            P P           +P    P P T A    P   AG    AP V     A      G 
Sbjct: 254 APSPPAAPAPAAPAAAPPPPPPAPATLA--RPPGHPAGPPTAAPAVPPPAAAQNGGSAG- 310

Query: 224 AAPSRSPSETG 234
           AAP+ +P+  G
Sbjct: 311 AAPAPAPAAGG 321



 Score = 33.5 bits (75), Expect = 0.36
 Identities = 55/218 (25%), Positives = 71/218 (32%), Gaps = 40/218 (18%)

Query: 24  PVPSLRGPPTTAVPCPRDDPQAEPQAPGRPTAPGLAAAAAADKLEPPRELRKRGEAASGS 83
           P   ++ PP      P       P AP  P AP  AA AAA    PP            +
Sbjct: 234 PGTVIQTPPFVGAAAP-----PAPAAPSPPAAPAPAAPAAAPPPPPP------------A 276

Query: 84  GAELQEQAGCEA-PEAAAPRERPARLSAREYSRQVHEWLWQSYCGYLTWHSGLAAFPAYC 142
            A L    G  A P  AAP   P   +    S            G     +  A  PA  
Sbjct: 277 PATLARPPGHPAGPPTAAPAVPPPAAAQNGGS-----------AGAAPAPAPAAGGPAGV 325

Query: 143 SPQPSPQSFPSGGAAVPQAAAPPPPQLGYYNPFYFLSPGAAGP---------DPRTAAGI 193
           S QP P +  +  A  P   A  P ++    P    +  A+GP          P     +
Sbjct: 326 SGQPGPGA--AAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGAL 383

Query: 194 STPAPVAGLGPRAPHVQASVRATPVTRVGSAAPSRSPS 231
            +PA V    P  P       A  VT+  S  P+ + S
Sbjct: 384 PSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTS 421



 Score = 32.0 bits (71), Expect = 1.1
 Identities = 27/97 (27%), Positives = 35/97 (36%), Gaps = 1/97 (1%)

Query: 143 SPQPSPQSFPSGGAAVPQAAAPPPPQLGYYNPFYFLSPGAAGPDPRTAAGISTPA-PVAG 201
           SP  +  + P+  A     AAP PP  G   P          P PR     + PA P A 
Sbjct: 66  SPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAK 125

Query: 202 LGPRAPHVQASVRATPVTRVGSAAPSRSPSETGRQAG 238
           L P       S    P     +A P  +P+   + AG
Sbjct: 126 LRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAG 162


>gi|239749077 PREDICTED: hypothetical protein XP_002346898 [Homo
           sapiens]
          Length = 334

 Score = 40.0 bits (92), Expect = 0.004
 Identities = 58/217 (26%), Positives = 76/217 (35%), Gaps = 40/217 (18%)

Query: 28  LRGPPTTAVPCPRDDPQAEPQAPGRPTAPGLAAAAAADK---LEPPRELRKRGEAASGS- 83
           LRG  T  V C       + +  GR  APG  A    +K      PR    RG    G  
Sbjct: 14  LRGSDTAGVTCRVSSQDGDRRGLGREAAPGAPAEGEKEKGKNSRRPRPTCSRGRTERGRV 73

Query: 84  --GAELQEQAGCEAPEAAAPRERPARLSAREYSRQVHEWLWQSYCGYLTWHSGLAAFPAY 141
             GA+ QE+       A AP  RP   +A      VH  L                  A 
Sbjct: 74  ERGADHQERP------AGAPAHRPVPAAAAILRAAVHRVL--------------RVLRAA 113

Query: 142 CSPQPSPQSFPSGGAAVPQAAAPPPPQLGYYNPFYFLSPGAAGPDPRTAAGISTPAPVAG 201
            + + + +     G   P+  APP  QL           G  G     +AG     P  G
Sbjct: 114 AAVRDAERGLRREG---PRRHAPPRKQLR----------GRRGAAGLVSAGHLGREPPRG 160

Query: 202 LGPRAPHVQASVRATPVTRVGSAAPS-RSPSETGRQA 237
            G R P +     ATP+   G + PS R+ + +G QA
Sbjct: 161 GGLRPPALVPVPLATPLLLEGRSEPSTRACAVSGGQA 197


>gi|239743103 PREDICTED: hypothetical protein XP_002342755 [Homo
           sapiens]
          Length = 329

 Score = 40.0 bits (92), Expect = 0.004
 Identities = 58/217 (26%), Positives = 76/217 (35%), Gaps = 40/217 (18%)

Query: 28  LRGPPTTAVPCPRDDPQAEPQAPGRPTAPGLAAAAAADK---LEPPRELRKRGEAASGS- 83
           LRG  T  V C       + +  GR  APG  A    +K      PR    RG    G  
Sbjct: 9   LRGSDTAGVTCRVSSQDGDRRGLGREAAPGAPAEGEKEKGKNSRRPRPTCSRGRTERGRV 68

Query: 84  --GAELQEQAGCEAPEAAAPRERPARLSAREYSRQVHEWLWQSYCGYLTWHSGLAAFPAY 141
             GA+ QE+       A AP  RP   +A      VH  L                  A 
Sbjct: 69  ERGADHQERP------AGAPAHRPVPAAAAILRAAVHRVL--------------RVLRAA 108

Query: 142 CSPQPSPQSFPSGGAAVPQAAAPPPPQLGYYNPFYFLSPGAAGPDPRTAAGISTPAPVAG 201
            + + + +     G   P+  APP  QL           G  G     +AG     P  G
Sbjct: 109 AAVRDAERGLRREG---PRRHAPPRKQLR----------GRRGAAGLVSAGHLGREPPRG 155

Query: 202 LGPRAPHVQASVRATPVTRVGSAAPS-RSPSETGRQA 237
            G R P +     ATP+   G + PS R+ + +G QA
Sbjct: 156 GGLRPPALVPVPLATPLLLEGRSEPSTRACAVSGGQA 192


>gi|239508758 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 329

 Score = 40.0 bits (92), Expect = 0.004
 Identities = 58/217 (26%), Positives = 76/217 (35%), Gaps = 40/217 (18%)

Query: 28  LRGPPTTAVPCPRDDPQAEPQAPGRPTAPGLAAAAAADK---LEPPRELRKRGEAASGS- 83
           LRG  T  V C       + +  GR  APG  A    +K      PR    RG    G  
Sbjct: 9   LRGSDTAGVTCRVSSQDGDRRGLGREAAPGAPAEGEKEKGKNSRRPRPTCSRGRTERGRV 68

Query: 84  --GAELQEQAGCEAPEAAAPRERPARLSAREYSRQVHEWLWQSYCGYLTWHSGLAAFPAY 141
             GA+ QE+       A AP  RP   +A      VH  L                  A 
Sbjct: 69  ERGADHQERP------AGAPAHRPVPAAAAILRAAVHRVL--------------RVLRAA 108

Query: 142 CSPQPSPQSFPSGGAAVPQAAAPPPPQLGYYNPFYFLSPGAAGPDPRTAAGISTPAPVAG 201
            + + + +     G   P+  APP  QL           G  G     +AG     P  G
Sbjct: 109 AAVRDAERGLRREG---PRRHAPPRKQLR----------GRRGAAGLVSAGHLGREPPRG 155

Query: 202 LGPRAPHVQASVRATPVTRVGSAAPS-RSPSETGRQA 237
            G R P +     ATP+   G + PS R+ + +G QA
Sbjct: 156 GGLRPPALVPVPLATPLLLEGRSEPSTRACAVSGGQA 192


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.135    0.416 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,308,482
Number of Sequences: 37866
Number of extensions: 1293222
Number of successful extensions: 12390
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 127
Number of HSP's successfully gapped in prelim test: 863
Number of HSP's that attempted gapping in prelim test: 8904
Number of HSP's gapped (non-prelim): 3810
length of query: 413
length of database: 18,247,518
effective HSP length: 105
effective length of query: 308
effective length of database: 14,271,588
effective search space: 4395649104
effective search space used: 4395649104
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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