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Search of human proteins with 14043024
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|14043024 BCL2-associated athanogene 3 [Homo sapiens]
(575 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|14043024 BCL2-associated athanogene 3 [Homo sapiens] 1179 0.0
gi|6631075 BCL2-associated athanogene 4 [Homo sapiens] 103 6e-22
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 75 2e-13
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 75 2e-13
gi|62548856 BCL2-associated athanogene 5 isoform a [Homo sapiens] 73 6e-13
gi|6631077 BCL2-associated athanogene 5 isoform b [Homo sapiens] 73 6e-13
gi|62548854 BCL2-associated athanogene 5 isoform b [Homo sapiens] 73 6e-13
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 72 1e-12
gi|50345997 E1A binding protein p300 [Homo sapiens] 69 1e-11
gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 67 4e-11
gi|163965366 nascent polypeptide-associated complex alpha subuni... 66 8e-11
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 65 1e-10
gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens] 65 2e-10
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 63 6e-10
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 63 6e-10
gi|150170670 piccolo isoform 2 [Homo sapiens] 63 8e-10
gi|150378539 piccolo isoform 1 [Homo sapiens] 63 8e-10
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 62 1e-09
gi|47132519 Ras association and pleckstrin homology domains 1 is... 60 5e-09
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 60 7e-09
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 58 2e-08
gi|110349719 titin isoform N2-A [Homo sapiens] 58 3e-08
gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Hom... 58 3e-08
gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Hom... 58 3e-08
gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo ... 58 3e-08
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 58 3e-08
gi|33286436 gametogenetin [Homo sapiens] 58 3e-08
gi|18079216 CASK interacting protein 1 [Homo sapiens] 57 4e-08
gi|222352183 neural precursor cell expressed, developmentally do... 57 4e-08
gi|21361472 neural precursor cell expressed, developmentally dow... 57 4e-08
>gi|14043024 BCL2-associated athanogene 3 [Homo sapiens]
Length = 575
Score = 1179 bits (3049), Expect = 0.0
Identities = 575/575 (100%), Positives = 575/575 (100%)
Query: 1 MSAATHSPMMQVASGNGDRDPLPPGWEIKIDPQTGWPFFVDHNSRTTTWNDPRVPSEGPK 60
MSAATHSPMMQVASGNGDRDPLPPGWEIKIDPQTGWPFFVDHNSRTTTWNDPRVPSEGPK
Sbjct: 1 MSAATHSPMMQVASGNGDRDPLPPGWEIKIDPQTGWPFFVDHNSRTTTWNDPRVPSEGPK 60
Query: 61 ETPSSANGPSREGSRLPPAREGHPVYPQLRPGYIPIPVLHEGAENRQVHPFHVYPQPGMQ 120
ETPSSANGPSREGSRLPPAREGHPVYPQLRPGYIPIPVLHEGAENRQVHPFHVYPQPGMQ
Sbjct: 61 ETPSSANGPSREGSRLPPAREGHPVYPQLRPGYIPIPVLHEGAENRQVHPFHVYPQPGMQ 120
Query: 121 RFRTEAAAAAPQRSQSPLRGMPETTQPDKQCGQVAAAAAAQPPASHGPERSQSPAASDCS 180
RFRTEAAAAAPQRSQSPLRGMPETTQPDKQCGQVAAAAAAQPPASHGPERSQSPAASDCS
Sbjct: 121 RFRTEAAAAAPQRSQSPLRGMPETTQPDKQCGQVAAAAAAQPPASHGPERSQSPAASDCS 180
Query: 181 SSSSSASLPSSGRSSLGSHQLPRGYISIPVIHEQNVTRPAAQPSFHQAQKTHYPAQQGEY 240
SSSSSASLPSSGRSSLGSHQLPRGYISIPVIHEQNVTRPAAQPSFHQAQKTHYPAQQGEY
Sbjct: 181 SSSSSASLPSSGRSSLGSHQLPRGYISIPVIHEQNVTRPAAQPSFHQAQKTHYPAQQGEY 240
Query: 241 QTHQPVYHKIQGDDWEPRPLRAASPFRSSVQGASSREGSPARSSTPLHSPSPIRVHTVVD 300
QTHQPVYHKIQGDDWEPRPLRAASPFRSSVQGASSREGSPARSSTPLHSPSPIRVHTVVD
Sbjct: 241 QTHQPVYHKIQGDDWEPRPLRAASPFRSSVQGASSREGSPARSSTPLHSPSPIRVHTVVD 300
Query: 301 RPQQPMTHRETAPVSQPENKPESKPGPVGPELPPGHIPIQVIRKEVDSKPVSQKPPPPSE 360
RPQQPMTHRETAPVSQPENKPESKPGPVGPELPPGHIPIQVIRKEVDSKPVSQKPPPPSE
Sbjct: 301 RPQQPMTHRETAPVSQPENKPESKPGPVGPELPPGHIPIQVIRKEVDSKPVSQKPPPPSE 360
Query: 361 KVEVKVPPAPVPCPPPSPGPSAVPSSPKSVATEERAAPSTAPAEATPPKPGEAEAPPKHP 420
KVEVKVPPAPVPCPPPSPGPSAVPSSPKSVATEERAAPSTAPAEATPPKPGEAEAPPKHP
Sbjct: 361 KVEVKVPPAPVPCPPPSPGPSAVPSSPKSVATEERAAPSTAPAEATPPKPGEAEAPPKHP 420
Query: 421 GVLKVEAILEKVQGLEQAVDNFEGKKTDKKYLMIEEYLTKELLALDSVDPEGRADVRQAR 480
GVLKVEAILEKVQGLEQAVDNFEGKKTDKKYLMIEEYLTKELLALDSVDPEGRADVRQAR
Sbjct: 421 GVLKVEAILEKVQGLEQAVDNFEGKKTDKKYLMIEEYLTKELLALDSVDPEGRADVRQAR 480
Query: 481 RDGVRKVQTILEKLEQKAIDVPGQVQVYELQPSNLEADQPLQAIMEMGAVAADKGKKNAG 540
RDGVRKVQTILEKLEQKAIDVPGQVQVYELQPSNLEADQPLQAIMEMGAVAADKGKKNAG
Sbjct: 481 RDGVRKVQTILEKLEQKAIDVPGQVQVYELQPSNLEADQPLQAIMEMGAVAADKGKKNAG 540
Query: 541 NAEDPHTETQQPEATAAATSNPSSMTDTPGNPAAP 575
NAEDPHTETQQPEATAAATSNPSSMTDTPGNPAAP
Sbjct: 541 NAEDPHTETQQPEATAAATSNPSSMTDTPGNPAAP 575
>gi|6631075 BCL2-associated athanogene 4 [Homo sapiens]
Length = 457
Score = 103 bits (256), Expect = 6e-22
Identities = 132/488 (27%), Positives = 186/488 (38%), Gaps = 64/488 (13%)
Query: 23 PPGWEIKIDPQTG-WPFFVDHNSRTTTWNDPRVPSEGPKETPSSANGPSREGSRLPPARE 81
P G ++ + P +P + +W RV GP ET G +G
Sbjct: 23 PGGGDVPVHPPPPLYPLRPEPPQPPISW---RVRGGGPAETTWLGEGGGGDG-------- 71
Query: 82 GHPVYPQLRPGYIPIPVLHEGAENRQVHPFHVYPQPGMQRFRTEAAAAAPQRSQSPLRGM 141
YP G P P G+ Q YP + + A + AP S P+R
Sbjct: 72 ---YYPS--GGAWPEPGRAGGSHQEQPP----YPSYNSNYWNSTARSRAPYPSTYPVR-- 120
Query: 142 PETTQPDKQCGQVAAAAAAQPPASHGPERSQSPA--ASDCSSSSSSASLPSSGRSSLGSH 199
PE A PP S S A A + +S S +PS+ RSS
Sbjct: 121 PELQGQSLNSYTNGAYGPTYPPGPGANTASYSGAYYAPGYTQTSYSTEVPSTYRSS---- 176
Query: 200 QLPRGYISIPV---IHEQNVTRPAAQPSFHQAQKTHYPAQQGEYQTHQPVYHKIQGDDWE 256
G PV I+ Q + A P + Q YP Q T P Y G+
Sbjct: 177 ----GNSPTPVSRWIYPQQDCQTEAPPL--RGQVPGYPPSQNPGMT-LPHYPYGDGNRSV 229
Query: 257 PRPLRAASPFRSSVQGASSREGSPARSSTPLHSPS--PIRVHTVVDRPQQPMTHRETAPV 314
P+ P + + G R P +PS P ++ P + +P
Sbjct: 230 PQSGPTVRP-QEDAWASPGAYGMGGRYPWPSSAPSAPPGNLYMTESTSPWPSSGSPQSPP 288
Query: 315 SQPENKPESKPGPVGPE---LPPGHIPIQVIRKEVDSKPVSQKPPPPSEKVEVKVPPAPV 371
S P +P+ P + + P V + E + +V+ P
Sbjct: 289 SPPVQQPKDSSYPYSQSDQSMNRHNFPCSVHQYESSGTVNNDDSDLLDSQVQYSAEPQ-- 346
Query: 372 PCPPPSPGPSAVPSSPKSVATEERAAPSTAPAEATPPKPGEAEAPPKHPGVLKVEAILEK 431
+ + S + S+ P E P E+ P P + K+ +LEK
Sbjct: 347 -----------LYGNATSDHPNNQDQSSSLPEECVPSD----ESTP--PSIKKIIHVLEK 389
Query: 432 VQGLEQAVDNFEGKKTDKKYLMIEEYLTKELLALDSVDPEGRADVRQARRDGVRKVQTIL 491
VQ LEQ V+ F GKKTDK Y ++EE LTKELL LDSV+ G+ VRQAR++ V K+Q IL
Sbjct: 390 VQYLEQEVEEFVGKKTDKAYWLLEEMLTKELLELDSVETGGQDSVRQARKEAVCKIQAIL 449
Query: 492 EKLEQKAI 499
EKLE+K +
Sbjct: 450 EKLEKKGL 457
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 74.7 bits (182), Expect = 2e-13
Identities = 112/422 (26%), Positives = 156/422 (36%), Gaps = 59/422 (13%)
Query: 52 PRVPSEGPKETPSSANG-----PSREGSRLPPAREG--HPVYPQLRPGYIPIPV------ 98
PR P+EGP+++ SSA+ PS R P A G P L P+
Sbjct: 198 PRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGP 257
Query: 99 LHEGAENRQVHPFHVYPQPGMQRFRT--------EAAAAAPQRSQSPLRG-MPETTQ--- 146
G HP P+ G+Q R +AA A S SPL P T+
Sbjct: 258 SARGTPRAPAHPSQPKPK-GLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARP 316
Query: 147 ---PDKQCGQVAAAAAAQPP-ASHGPERSQSPAASDCSSS--SSSASLPSSGRSSLGSH- 199
PD + A PP A+ P SP+A + S A+ PS S+ +
Sbjct: 317 VPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPP 376
Query: 200 -QLPRGYISIPVIH-EQNVTRPAAQP--------SFHQAQKTHYPAQQGEYQTHQPVYHK 249
Q P +IP I ++T P+ Q S P Q + +
Sbjct: 377 MQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQ 436
Query: 250 IQGDDWEPRPLRAASPFRSSVQGASSREGSPA--RSSTPLHSP--SPIRVHTVVDRPQQP 305
Q P + P +Q S SP S +P SP SP+ +H +
Sbjct: 437 TQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPL-QALSSL 495
Query: 306 MTHRETAPVSQ---PENKPESKPGPVGPELPPGHIPIQVIRKEVD-SKPVSQKPPPPSEK 361
+H AP+S P + +S P + PP + + + P Q P
Sbjct: 496 ASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTT 555
Query: 362 VEVKVPPAPVPCP---PPSPGPSAVPSSPKSVATEERAAPSTAPAEATPPKPGEAEAPPK 418
++ PP P PCP PPSP + P +P S+AT AP PA A+PP G +PP
Sbjct: 556 PHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAP---PALASPPLQG-LPSPPL 611
Query: 419 HP 420
P
Sbjct: 612 SP 613
Score = 63.2 bits (152), Expect = 6e-10
Identities = 88/376 (23%), Positives = 137/376 (36%), Gaps = 28/376 (7%)
Query: 59 PKETPSSANGPSREGSRLPPAREGHPVYPQLR-PGYIPIPVLHEGAENRQVHPFHVYPQP 117
P++T +S PSR S P + P+ L P P+ A + P ++P
Sbjct: 434 PRQTQASLTSPSRPASTPP---DSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQ 490
Query: 118 GMQRFRTEAAAAAPQRSQSPLRGMPETTQPD--KQCGQVAAAAAAQPPASHGPERSQSPA 175
+ + A+ +PQ S L P TQ Q A+ PP + P + P
Sbjct: 491 AL----SSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPL 546
Query: 176 ASDCSSSSSSASLPSSGRSSLGSHQLPRGYISIPVIHEQNVTRPAAQPSFHQAQKTHYPA 235
+ S+ ++ L + + Q P ++ P A P P
Sbjct: 547 QT-ASAPLTTPHLETPPCPAPCPLQAPPSPLTTP---PPETPSSIATPPPQAPPALASPP 602
Query: 236 QQGEYQTHQPVYHKIQGDDWEPRPLRAASPFRSSVQGASSREGSPARSSTPLHSPSPIRV 295
QG P + + P A P ++ +S SP + +P +P+ + V
Sbjct: 603 LQG---LPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSP-QAPNALAV 658
Query: 296 HTVVDRPQQPMTHRETAPVSQPENKPESKPGPVGPELPPGHI--PIQVIRKEVDSKPVSQ 353
H + P + AP S P + P S + PP P+QV S P+S
Sbjct: 659 HLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSP 718
Query: 354 ------KPPPPSEKVEVKVPPAPVPCPPPSPGPSAVPSSPKSVATEERAAPSTAPAEATP 407
+ PPP ++VPP+P PP SP + P P +A P + PA
Sbjct: 719 SATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASL-- 776
Query: 408 PKPGEAEAPPKHPGVL 423
P A+ PP+ P L
Sbjct: 777 PMSPLAKPPPQAPPAL 792
Score = 56.6 bits (135), Expect = 6e-08
Identities = 101/422 (23%), Positives = 146/422 (34%), Gaps = 91/422 (21%)
Query: 54 VPSEGPKETP------SSANGPSR-----EGSRLPPAREGHP--------VYPQLRPGYI 94
+P P+ P SS N SR G R PPA+ P RPG +
Sbjct: 70 IPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPL 129
Query: 95 PIPVLHEGAENRQVHPFHVYPQPGMQRFRTEAAAAAPQRSQSPLRGMPETTQPDK----- 149
L AE + R+ +A A + + P G P +
Sbjct: 130 GQKGLRISAEETVAR-----GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAG 184
Query: 150 -QCGQVAAAAAAQP-PASHGPERSQSPAASDCSSSSSSAS--LPSSGRSSLGSHQLPRGY 205
+ G A +A+P P + GP +S S A+ ++ S A+ PS+G
Sbjct: 185 TEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAG------------- 231
Query: 206 ISIPVIHEQNVTRPAAQPSFHQAQKTHYPAQQGEYQTHQPVYHKIQGDDWEPRP--LRAA 263
+ RPA++ A PA+ G P + +P+P L+A
Sbjct: 232 --------GGLQRPASRSLSSSATPLSSPARSGPSARGTP---RAPAHPSQPKPKGLQAL 280
Query: 264 SPFRSSVQGASSREGSPARSSTPLHSPSPIRVHTVVDRPQQPMTHRET-APVSQPENKPE 322
P + + + SS+PL +PSP RP P + T P + P + P
Sbjct: 281 RPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKA---RPVPPPDNAATPLPATLPPSPPL 337
Query: 323 SKPGPVGPELPPGHIPIQVIRKEVDSKPVSQKPP---------PPSEKVEVKVPPAPVPC 373
+ P P+ P P +Q + + P SQ PP PPS + +PP VP
Sbjct: 338 ATPLPLAPPSPSAPPSLQTL-PSPPATPPSQAPPSMTTPPMQAPPSLQT---IPPIQVPH 393
Query: 374 PPPSPGPSAVPS--------------SPKSVATEERAAPSTAPAEATPPKPGE-AEAPPK 418
SP A PS SP AT S +A+ P A PP
Sbjct: 394 SLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPD 453
Query: 419 HP 420
P
Sbjct: 454 SP 455
Score = 56.6 bits (135), Expect = 6e-08
Identities = 85/334 (25%), Positives = 113/334 (33%), Gaps = 34/334 (10%)
Query: 110 PFHVYPQPGMQRFRTEAAAAAPQRSQSPLRGMPET---------TQPDKQCGQVAAAAAA 160
P P P + T A P + PL+ P P Q A
Sbjct: 602 PLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLL 661
Query: 161 QPPASHGPERS-QSPAASDCSSS-SSSASLPSSGRSSLGSH--QLPRGYISIPVIHEQNV 216
Q P S P Q+P + S S SA+ PS SL + Q+P + P +
Sbjct: 662 QAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSAT 721
Query: 217 TRPAAQPSFHQAQKTHYPAQQGEYQTHQPVYHKIQGDDWEPRPLRAASPFRSSVQGASSR 276
P A P P Q P PL AA P + +S
Sbjct: 722 PPPQAPPPLAAP-----PLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASL 776
Query: 277 EGSPARSSTPLHSPSPIRVHTVVDRPQQPMTHRETAPVSQPENKPESKPGPVGPELPPG- 335
SP P +P + + P P + AP S + P S P+ PP
Sbjct: 777 PMSPLAKPPP-QAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVL 835
Query: 336 HIPIQVIRKEVDSKPVSQ---KPPPPSEKVEVKVPP-----APVPCPPPSPGPSAVPSSP 387
P+ + + P Q +PP P V P AP P PPPS PS+ S P
Sbjct: 836 AAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGP 895
Query: 388 KSVATEERAAPSTAPAEA----TPPKPGEAEAPP 417
+A +A ST P E + P+ G A +PP
Sbjct: 896 -DLAGHSSSATST-PEELRGYDSGPEGGAAASPP 927
Score = 49.3 bits (116), Expect = 1e-05
Identities = 91/383 (23%), Positives = 124/383 (32%), Gaps = 76/383 (19%)
Query: 59 PKETPSSANGPSREGSRLPPAREGHPVYPQLRPGYIPIPVLHEGAENRQVHPFHVYPQPG 118
P ET SS PS + PPA P L P P P+ A H P P
Sbjct: 511 PLETQSSLAPPSLQ---TPPASLTTPPLENL-PSLAPPPLQTASAPLTTPH-LETPPCP- 564
Query: 119 MQRFRTEAAAAAPQRSQSPLRGMPETTQPDKQCGQVAAAAAAQPPASHGPERSQSPAASD 178
AP Q+P P TT P + +A PPA P
Sbjct: 565 -----------APCPLQAP--PSPLTTPPPETPSSIATPPPQAPPALASPPLQ------- 604
Query: 179 CSSSSSSASLPSSGRSSLGSH--QLPRGYISIPVIHEQNVTRPAAQPSFHQAQKTHYPAQ 236
LPS S L + Q P P + + P + P+ P+
Sbjct: 605 --------GLPSPPLSPLATPPPQAP------PXLALPPLQAPPSPPASPPLSPLATPSP 650
Query: 237 QGEYQTHQPVYHKIQGDDWEPRPLRAASPFRSSVQGASSREGSPARSSTPLHSPSPIRVH 296
Q + H +Q P +PF S +P + P + P++V
Sbjct: 651 QAP---NALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQV- 706
Query: 297 TVVDRPQQPMTHRETAPVSQPENKPESKPGPVGPELPPGHIPIQVIRKEVDSKPVSQKPP 356
+P + P P + P P P P P+QV S P+S
Sbjct: 707 -------------PPSPPASPPMSPSATPPPQAPP-PLAAPPLQVPPSPPASPPMSPSAT 752
Query: 357 PPSE------KVEVKVPPAPVPCPPPSPGPSAVPSSPKSVATEERAAPSTAPA------- 403
PP ++VPP+P P SP P +P ++AT A + PA
Sbjct: 753 PPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAP 812
Query: 404 ---EATPPKPGEAEAPPKHPGVL 423
A+ P A PP+ P VL
Sbjct: 813 FSPSASLPMSPLATPPPQAPPVL 835
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 74.7 bits (182), Expect = 2e-13
Identities = 102/406 (25%), Positives = 137/406 (33%), Gaps = 45/406 (11%)
Query: 56 SEGPKETPSSANGPSREGSRLPPAREGHPVYPQ---LRPGYIPIP---VLHEGAENRQVH 109
S GP +P A+G +R G P ++G + + R P L GA
Sbjct: 101 SPGPVSSPGRASGTTRPG---PLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSG 157
Query: 110 PFHVYPQPGM-QRFRTEAAAAAPQRSQSPLRGMPETTQPDKQCGQVAAAAAAQP-PASHG 167
P P P M +R R R R P T P K + + +P PA+
Sbjct: 158 PTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARR 217
Query: 168 PERS----QSPAASDCSSSSSSASLPS-SGRSSLGSHQLPRGYISIPVIHEQNVTRPAAQ 222
+ Q PA+ SSS++ S P+ SG S+ G+ + P Q + P
Sbjct: 218 RPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVT 277
Query: 223 PSFHQAQKTHYPAQQGEYQTHQPVYHKIQGDDWEPRPLRAASPFRSSVQGASSREGSPAR 282
P A P T P P SP + A++ GSP
Sbjct: 278 PPRKDAAPALGPLSSSPLATPSP--SAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTL 335
Query: 283 SSTPLHSPSPIRVHTVVDRPQQPMT------HRETAPVSQPENKPESKPGPVGPEL---- 332
+T PSP PQ P +P + P P + P P P
Sbjct: 336 QATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVH 395
Query: 333 -------PPGHIPIQVIRKEVDSKPVSQKPPPPSEKV-EVKVPPAPVP-----CPPPSPG 379
PP P+Q S PVS PPS+ + PP VP PP SP
Sbjct: 396 LLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPS 455
Query: 380 PSAVPSSPKSVATE----ERAAPSTAPAEATPPKPGEAEAPPKHPG 421
+ P +P +A + P PA ATPP P PG
Sbjct: 456 ATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPG 501
Score = 57.4 bits (137), Expect = 4e-08
Identities = 105/452 (23%), Positives = 146/452 (32%), Gaps = 107/452 (23%)
Query: 52 PRVPSEGPKETPSSANG-----PSREGSRLPPAREG--HPVYPQLRPGYIPIPV------ 98
PR P+EGP+++ SSA+ PS R P A G P L P+
Sbjct: 189 PRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGP 248
Query: 99 LHEGAENRQVHPFHVYPQPGMQRFRTEAAAAAPQRSQSPLRGMPETTQPDKQCGQVAAAA 158
G HP P+ G+Q R P+ T P K
Sbjct: 249 SARGTPRAPAHPSQPKPK-GLQALRP-----------------PQVTPPRKDAAPALGPL 290
Query: 159 AAQPPASHGPERSQSPAASDCSSS--SSSASLPSSGRSSLGSH--QLPRGYISIPVIHEQ 214
++ P A+ P SP+A + S A+ PS +SLGS Q ++ P +
Sbjct: 291 SSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPL 350
Query: 215 NVTRPAAQPSFHQAQKTHYPAQQGE-----YQTHQP------VYHKIQGDDWEPRPLRAA 263
P A P+ P+ T P H +Q P
Sbjct: 351 ATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ 410
Query: 264 SPFRSSVQGASSREGSPARSSTPLHSPSPIRVHTVVDRPQQPMTHRETAPVSQP------ 317
+PF S +P + P + P++V PM+ T P P
Sbjct: 411 APFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPA-SPPMSPSATPPPQAPPPLAAP 469
Query: 318 -----ENKPESKPGPVGPEL-----PPGHIPIQVIRKEVDSKPVSQKPPPPSEKVEV--- 364
+ P++ P P L PP P Q S P+S PP + V
Sbjct: 470 PLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAA 529
Query: 365 ---KVPP--------------------------------APVPCPPPSPGPSAVPSSPKS 389
+VPP AP P PPPS PS+ S P
Sbjct: 530 PLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGP-D 588
Query: 390 VATEERAAPSTAPAEA----TPPKPGEAEAPP 417
+A +A ST P E + P+ G A +PP
Sbjct: 589 LAGHSSSATST-PEELRGYDSGPEGGAAASPP 619
Score = 53.9 bits (128), Expect = 4e-07
Identities = 72/309 (23%), Positives = 113/309 (36%), Gaps = 41/309 (13%)
Query: 149 KQCGQVAAAAAAQPPASHGPERSQSPAASDC------SSSSSSASLPSSGRSSLGSHQLP 202
++ G + A + GP R+ P AS + ++S + S GR+S + P
Sbjct: 60 ERAGGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGP 119
Query: 203 RGYISIPVIHEQNVTRPAAQPSFHQAQKTHYPAQQGEYQTHQP--------VYHKIQGDD 254
G + + E+ V R A +A K + T P + + +
Sbjct: 120 LGQKGLRISAEETVARGKAT----EAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAG 175
Query: 255 WE---PRPLRAASPFRSSVQGASSREGSPARSSTPLHSPSPIRVHTVVDRPQQPMTHRET 311
E PRP +A P R +G S + ST SP+ R + Q+P + +
Sbjct: 176 TEVGLPRPAPSARP-RPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLS 234
Query: 312 APVSQPENKPESKPGPVGPELPPGHIPIQVIRKEVDSKPVSQKPPPPSEKVEVKVPPAPV 371
+ + + S P G P H P Q K + + Q PP + P +
Sbjct: 235 SSATPLSSPARSGPSARGTPRAPAH-PSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSS 293
Query: 372 PCPPPSPGPSAVPSSPKSVATEERAAPSTAPAEAT-----------------PPKPGEAE 414
P PSP PS+P S+ T + P+T P++AT PP A
Sbjct: 294 PLATPSPSAPPSPSAPPSLQTLP-SPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLAT 352
Query: 415 APPKHPGVL 423
PP+ P L
Sbjct: 353 PPPQAPPAL 361
Score = 31.2 bits (69), Expect = 2.7
Identities = 21/80 (26%), Positives = 33/80 (41%), Gaps = 8/80 (10%)
Query: 350 PVSQKPPPPSEKVEVKVPPA-------PVPCPPPSPGPSAVP-SSPKSVATEERAAPSTA 401
P S +PPPP ++V A P+ G + +P S+P++ T P++
Sbjct: 30 PGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRPPASG 89
Query: 402 PAEATPPKPGEAEAPPKHPG 421
E PP + P PG
Sbjct: 90 RGERAPPAKNTSPGPVSSPG 109
>gi|62548856 BCL2-associated athanogene 5 isoform a [Homo sapiens]
Length = 488
Score = 73.2 bits (178), Expect = 6e-13
Identities = 33/93 (35%), Positives = 61/93 (65%), Gaps = 1/93 (1%)
Query: 418 KHPGVLKVEAILEKVQGLEQAVDNFEGKKTDKKYLMIEEYLTKELLALDSVDPEGRADVR 477
+HP + +++ I ++V+ +EQ V F G DK Y +E LTK+L +DSVD EG+ D++
Sbjct: 47 QHPSISRLQEIQKEVKSVEQQVIGFSGLSDDKNYKKLERILTKQLFEIDSVDTEGKGDIQ 106
Query: 478 QARRDGVRKVQTILEKLEQKAIDVPGQVQVYEL 510
QAR+ ++ + +L++LEQ A + P ++++ +
Sbjct: 107 QARKRAAQETERLLKELEQNA-NHPHRIEIQNI 138
Score = 71.2 bits (173), Expect = 2e-12
Identities = 38/85 (44%), Positives = 52/85 (61%), Gaps = 3/85 (3%)
Query: 414 EAPPKHPGVLKVEAILEKVQGLEQAVDNFEGKKTDKKYLMIEEYLTKELLALDSVDPEGR 473
E P H V V L ++QG V +F+G +TDK Y+ +EE LTK+LLALD+VDP+G
Sbjct: 402 EEHPSHKAVWNVLGNLSEIQG---EVLSFDGNRTDKNYIRLEELLTKQLLALDAVDPQGE 458
Query: 474 ADVRQARRDGVRKVQTILEKLEQKA 498
+ AR+ VR Q IL L+ K+
Sbjct: 459 EKCKAARKQAVRLAQNILSYLDLKS 483
Score = 34.7 bits (78), Expect = 0.24
Identities = 29/121 (23%), Positives = 58/121 (47%), Gaps = 3/121 (2%)
Query: 422 VLKVEAILEKVQGLEQAVDNFEGKKTDKKYLMIEEYLTKELLALDSVDPEGRADVRQARR 481
+LK+E +L++++ ++ + + + + YL + L + LD V E +R+ARR
Sbjct: 317 ILKIEKVLKRMREIKNEL--LQAQNPSELYLSSKTELQGLIGQLDEVSLEKNPCIREARR 374
Query: 482 DGVRKVQTILEKLEQKAIDVPGQVQVYELQPSNLEADQPLQAIMEM-GAVAADKGKKNAG 540
V +VQT++ ++ K ++ E PS+ L + E+ G V + G +
Sbjct: 375 RAVIEVQTLITYIDLKEALEKRKLFACEEHPSHKAVWNVLGNLSEIQGEVLSFDGNRTDK 434
Query: 541 N 541
N
Sbjct: 435 N 435
>gi|6631077 BCL2-associated athanogene 5 isoform b [Homo sapiens]
Length = 447
Score = 73.2 bits (178), Expect = 6e-13
Identities = 33/93 (35%), Positives = 61/93 (65%), Gaps = 1/93 (1%)
Query: 418 KHPGVLKVEAILEKVQGLEQAVDNFEGKKTDKKYLMIEEYLTKELLALDSVDPEGRADVR 477
+HP + +++ I ++V+ +EQ V F G DK Y +E LTK+L +DSVD EG+ D++
Sbjct: 6 QHPSISRLQEIQKEVKSVEQQVIGFSGLSDDKNYKKLERILTKQLFEIDSVDTEGKGDIQ 65
Query: 478 QARRDGVRKVQTILEKLEQKAIDVPGQVQVYEL 510
QAR+ ++ + +L++LEQ A + P ++++ +
Sbjct: 66 QARKRAAQETERLLKELEQNA-NHPHRIEIQNI 97
Score = 71.2 bits (173), Expect = 2e-12
Identities = 38/85 (44%), Positives = 52/85 (61%), Gaps = 3/85 (3%)
Query: 414 EAPPKHPGVLKVEAILEKVQGLEQAVDNFEGKKTDKKYLMIEEYLTKELLALDSVDPEGR 473
E P H V V L ++QG V +F+G +TDK Y+ +EE LTK+LLALD+VDP+G
Sbjct: 361 EEHPSHKAVWNVLGNLSEIQG---EVLSFDGNRTDKNYIRLEELLTKQLLALDAVDPQGE 417
Query: 474 ADVRQARRDGVRKVQTILEKLEQKA 498
+ AR+ VR Q IL L+ K+
Sbjct: 418 EKCKAARKQAVRLAQNILSYLDLKS 442
Score = 34.7 bits (78), Expect = 0.24
Identities = 29/121 (23%), Positives = 58/121 (47%), Gaps = 3/121 (2%)
Query: 422 VLKVEAILEKVQGLEQAVDNFEGKKTDKKYLMIEEYLTKELLALDSVDPEGRADVRQARR 481
+LK+E +L++++ ++ + + + + YL + L + LD V E +R+ARR
Sbjct: 276 ILKIEKVLKRMREIKNEL--LQAQNPSELYLSSKTELQGLIGQLDEVSLEKNPCIREARR 333
Query: 482 DGVRKVQTILEKLEQKAIDVPGQVQVYELQPSNLEADQPLQAIMEM-GAVAADKGKKNAG 540
V +VQT++ ++ K ++ E PS+ L + E+ G V + G +
Sbjct: 334 RAVIEVQTLITYIDLKEALEKRKLFACEEHPSHKAVWNVLGNLSEIQGEVLSFDGNRTDK 393
Query: 541 N 541
N
Sbjct: 394 N 394
>gi|62548854 BCL2-associated athanogene 5 isoform b [Homo sapiens]
Length = 447
Score = 73.2 bits (178), Expect = 6e-13
Identities = 33/93 (35%), Positives = 61/93 (65%), Gaps = 1/93 (1%)
Query: 418 KHPGVLKVEAILEKVQGLEQAVDNFEGKKTDKKYLMIEEYLTKELLALDSVDPEGRADVR 477
+HP + +++ I ++V+ +EQ V F G DK Y +E LTK+L +DSVD EG+ D++
Sbjct: 6 QHPSISRLQEIQKEVKSVEQQVIGFSGLSDDKNYKKLERILTKQLFEIDSVDTEGKGDIQ 65
Query: 478 QARRDGVRKVQTILEKLEQKAIDVPGQVQVYEL 510
QAR+ ++ + +L++LEQ A + P ++++ +
Sbjct: 66 QARKRAAQETERLLKELEQNA-NHPHRIEIQNI 97
Score = 71.2 bits (173), Expect = 2e-12
Identities = 38/85 (44%), Positives = 52/85 (61%), Gaps = 3/85 (3%)
Query: 414 EAPPKHPGVLKVEAILEKVQGLEQAVDNFEGKKTDKKYLMIEEYLTKELLALDSVDPEGR 473
E P H V V L ++QG V +F+G +TDK Y+ +EE LTK+LLALD+VDP+G
Sbjct: 361 EEHPSHKAVWNVLGNLSEIQG---EVLSFDGNRTDKNYIRLEELLTKQLLALDAVDPQGE 417
Query: 474 ADVRQARRDGVRKVQTILEKLEQKA 498
+ AR+ VR Q IL L+ K+
Sbjct: 418 EKCKAARKQAVRLAQNILSYLDLKS 442
Score = 34.7 bits (78), Expect = 0.24
Identities = 29/121 (23%), Positives = 58/121 (47%), Gaps = 3/121 (2%)
Query: 422 VLKVEAILEKVQGLEQAVDNFEGKKTDKKYLMIEEYLTKELLALDSVDPEGRADVRQARR 481
+LK+E +L++++ ++ + + + + YL + L + LD V E +R+ARR
Sbjct: 276 ILKIEKVLKRMREIKNEL--LQAQNPSELYLSSKTELQGLIGQLDEVSLEKNPCIREARR 333
Query: 482 DGVRKVQTILEKLEQKAIDVPGQVQVYELQPSNLEADQPLQAIMEM-GAVAADKGKKNAG 540
V +VQT++ ++ K ++ E PS+ L + E+ G V + G +
Sbjct: 334 RAVIEVQTLITYIDLKEALEKRKLFACEEHPSHKAVWNVLGNLSEIQGEVLSFDGNRTDK 393
Query: 541 N 541
N
Sbjct: 394 N 394
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 72.0 bits (175), Expect = 1e-12
Identities = 98/404 (24%), Positives = 129/404 (31%), Gaps = 95/404 (23%)
Query: 52 PRVPSEGPKETPSSANG-----PSREGSRLPPAREG--HPVYPQLRPGYIPIPVLHEGAE 104
PR P+EGP+++ SSA+ PS R P A G P L P+
Sbjct: 198 PRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPL-------- 249
Query: 105 NRQVHPFHVYPQPGMQRFRTEAAAAAPQRSQSPLRGMPETTQPDKQCGQVAAAAAAQPPA 164
++P RS RG P Q + A +PP
Sbjct: 250 ------------------------SSPARSGPSARGTPRAPAHPSQ-PKPKGLQALRPPQ 284
Query: 165 SHGPERSQSPAASDCSSSSSSASLPSSGRSSLGSHQLPRGYISIPVIHEQNVTRPAAQPS 224
P + +PA SSS + PS+ S LP S + + P A PS
Sbjct: 285 VTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPS 344
Query: 225 FHQAQKTHYPAQQGEYQTHQPVYHKIQGDDWEPRPLRAASPFRSSVQGASSREGSPARSS 284
P+ QT SP + A++ GSP +
Sbjct: 345 ---------PSAPPSLQT-------------------LPSPPATPPSQATTSLGSPTLQA 376
Query: 285 TPLHSPSPIRVHTVVDRPQQPMT------HRETAPVSQPENKPESKPGPVGPEL------ 332
T PSP PQ P +P + P P + P P P
Sbjct: 377 THSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLL 436
Query: 333 -----PPGHIPIQVIRKEVDSKPVSQKPPPPSEKV-EVKVPPAPVP-----CPPPSPGPS 381
PP P+Q S PVS PPS+ + PP VP PP SP +
Sbjct: 437 QAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSAT 496
Query: 382 AVPSSPKSVATE----ERAAPSTAPAEATPPKPGEAEAPPKHPG 421
P +P +A + P PA ATPP P PG
Sbjct: 497 PPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPG 540
Score = 48.1 bits (113), Expect = 2e-05
Identities = 79/333 (23%), Positives = 117/333 (35%), Gaps = 67/333 (20%)
Query: 147 PDKQCGQVAAAAAAQPPASHGPERSQSPAASDCSSSSSSASLPSSGRSSLGSHQLPRGYI 206
P + G + A++PPAS ER+ + ++S + S GR+S + P G
Sbjct: 79 PTRSAGTSSRNPASRPPASGRGERAPP------AKNTSPGPVSSPGRASGTTRPGPLGQK 132
Query: 207 SIPVIHEQNVTRPAAQPSFHQAQKTHYPAQQGEYQTHQP--------VYHKIQGDDWE-- 256
+ + E+ V R A +A K + T P + + + E
Sbjct: 133 GLRISAEETVARGKAT----EAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVG 188
Query: 257 -PRPLRAASPFRSSVQGASSREGSPARSSTPLHSPSPIRVHTV---VDRPQQPMTHRETA 312
PRP +A P R +G S + ST SP+ R + + RP
Sbjct: 189 LPRPAPSARP-RPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSAT 247
Query: 313 PVSQPENKPESKPG----PVGPELP-PGHI----PIQVIRKEVDSKP----VSQKP---P 356
P+S P S G P P P P + P QV D+ P +S P P
Sbjct: 248 PLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATP 307
Query: 357 PPSEKVEVKVPPA----------------PVPCPPPSPG----------PSAVPSSPKSV 390
PS ++ + PP P+P PPSP P A P S +
Sbjct: 308 SPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATT 367
Query: 391 ATEERAAPSTAPAEATPPKPGEAEAPPKHPGVL 423
+ +T +PP A PP+ P L
Sbjct: 368 SLGSPTLQATHSFLPSPPLSPLATPPPQAPPAL 400
>gi|50345997 E1A binding protein p300 [Homo sapiens]
Length = 2414
Score = 68.9 bits (167), Expect = 1e-11
Identities = 111/472 (23%), Positives = 166/472 (35%), Gaps = 90/472 (19%)
Query: 77 PPAREGHPVYPQLRPGYIPIPVLHEGAENRQVHPFHVYPQPGMQRFRTEAAAAAPQRSQS 136
P G P G +P P + G+ Q+ P + PQ G+ +F + A P
Sbjct: 671 PGPNMGQPQPGMTSNGPLPDPSMIRGSVPNQMMP-RITPQSGLNQFGQMSMAQPPI---- 725
Query: 137 PLRGMPETTQPDKQCGQVAAAAAAQPPASHGPERSQSPA-----------ASDCSSSSSS 185
+P T P + GQ+A A PP +GP R Q P+ S + ++
Sbjct: 726 ----VPRQTPPLQHHGQLAQPGALNPPMGYGP-RMQQPSNQGQFLPQTQFPSQGMNVTNI 780
Query: 186 ASLPSSGRSSLGSHQLPRGYISIPVIHEQNVTRPAAQPSFHQAQKTHYPAQQGEYQTHQP 245
PSSG++ + Q+ S PV P Q H P Q QP
Sbjct: 781 PLAPSSGQAPVSQAQMSSS--SCPV-------NSPIMPPGSQGSHIHCP------QLPQP 825
Query: 246 VYHKIQGDDWEPRPLRAASPFRSSVQGASSREGSPARSSTPLHSPSPIRVHTVVDRPQQP 305
H+ P P+ P+R+ TP H+P I QQP
Sbjct: 826 ALHQNS-----PSPV-------------------PSRTPTPHHTPPSIGA-------QQP 854
Query: 306 MTHRETAPVSQPENKPESKPGPVGPEL--PPGHIPI-------QVIRKEVDSKPVSQKPP 356
APV P P PGP L PP P Q ++ + + P + +P
Sbjct: 855 PATTIPAPVPTP---PAMPPGPQSQALHPPPRQTPTPPTTQLPQQVQPSLPAAPSADQPQ 911
Query: 357 PPSEKVEVKVPPAPVPCPPPSPGPSAVPSSPKSVATEERAA--PSTAPAEATPPKPGEAE 414
+ P P P P A P S +V+ E + + PST+ E +A
Sbjct: 912 QQPRSQQSTAASVPTPTAPLLPPQPATPLSQPAVSIEGQVSNPPSTSSTEVN----SQAI 967
Query: 415 APPKHPGVLKVEAILEKVQ---GLEQAVDNFEGKKTDKKY--LMIEEYLTKELLALDSVD 469
A + +K+EA +E Q Q D E K D K EE T+ + +
Sbjct: 968 AEKQPSQEVKMEAKMEVDQPEPADTQPEDISESKVEDCKMESTETEERSTELKTEIKEEE 1027
Query: 470 PEGRADVRQARRDGVRKVQTILEKLEQKAIDVPGQVQVYELQPSNLEADQPL 521
+ Q+ + + I + E + +P +Y P +L QP+
Sbjct: 1028 DQPSTSATQSSPAPGQSKKKIFKPEELRQALMPTLEALYRQDPESLPFRQPV 1079
Score = 43.9 bits (102), Expect = 4e-04
Identities = 65/304 (21%), Positives = 113/304 (37%), Gaps = 34/304 (11%)
Query: 55 PSEGPKETPSSANGPSREGSRLPPAREGHPVYPQLRPGYIPI-PVLHEGAENRQVHPFHV 113
PS P TP+ + P G++ PPA P +P P + G +++ +HP
Sbjct: 832 PSPVPSRTPTPHHTPPSIGAQQPPA--------TTIPAPVPTPPAMPPGPQSQALHP--- 880
Query: 114 YPQPGMQRFRTEAAAAAPQRSQSPLRGMPETTQPDKQ--CGQVAAAAAAQPPASHGPERS 171
P Q T PQ+ Q L P QP +Q Q AA+ P A P +
Sbjct: 881 ---PPRQT-PTPPTTQLPQQVQPSLPAAPSADQPQQQPRSQQSTAASVPTPTAPLLPPQP 936
Query: 172 QSPAASDCSSSSSSAS-LPSSGRSSLGSHQLPRGYISIPVIHEQNVTRPAAQPSFHQAQK 230
+P + S S PS+ + + S + S V E + +P+ Q
Sbjct: 937 ATPLSQPAVSIEGQVSNPPSTSSTEVNSQAIAEKQPSQEVKMEAKMEVDQPEPADTQ--- 993
Query: 231 THYPAQQGEYQTHQPVYHKIQGDDWEPRPLRAASPFRSSVQGASSREGSPARSSTPLHSP 290
P E + K++ + E R ++ ++ ++ + + A S+P
Sbjct: 994 ---PEDISESKVED---CKMESTETEER----STELKTEIKEEEDQPSTSATQSSPAPGQ 1043
Query: 291 SPIRVHTVVDRPQQPMTHRETAPVSQPENKPESKPGPVGPELPPGHIPIQVIRKEVDSKP 350
S ++ + Q M E PE+ P + PV P+L +++ +D
Sbjct: 1044 SKKKIFKPEELRQALMPTLEALYRQDPESLPFRQ--PVDPQLLGIPDYFDIVKSPMDLST 1101
Query: 351 VSQK 354
+ +K
Sbjct: 1102 IKRK 1105
Score = 42.0 bits (97), Expect = 0.002
Identities = 87/413 (21%), Positives = 142/413 (34%), Gaps = 60/413 (14%)
Query: 51 DPRVPSEGPKETPSSANGPSREGSRLPPAREGHPVYPQLRPGYIPIPVLHEGAENRQVHP 110
+P + GP GP+ + P ++ G P QL+ G +P P + A++ Q P
Sbjct: 1968 NPPPMTRGPSGHLEPGMGPTGMQQQPPWSQGGLPQPQQLQSG-MPRPAMMSVAQHGQ--P 2024
Query: 111 FHVYPQPGMQRFRT---EAAAAAPQRSQSPLRGMPETTQPDKQCGQVAAAAAAQPP--AS 165
++ PQPG+ + + + Q Q+ LR + + P +Q QV + A P A+
Sbjct: 2025 LNMAPQPGLGQVGISPLKPGTVSQQALQNLLRTLRSPSSPLQQ-QQVLSILHANPQLLAA 2083
Query: 166 HGPERSQSPAASDCSSSSSSASLPSSGRSSLGSHQLP--RGYISIPVIHEQNVTRPAAQP 223
+R+ A S+ +P G+ L +P +G S P + N P
Sbjct: 2084 FIKQRAAKYANSNPQPIPGQPGMPQ-GQPGLQPPTMPGQQGVHSNPAMQNMN-------P 2135
Query: 224 SFHQAQKTHYPAQQGEYQTHQPV------------YHKIQGDDWEPRPLRAASPFRSSVQ 271
Q+ P QQ + Q P+ H + R + Q
Sbjct: 2136 MQAGVQRAGLPQQQPQQQLQPPMGGMSPQAQQMNMNHNTMPSQFRDILRRQQMMQQQQQQ 2195
Query: 272 GASSREGSPARSSTPLHSPSPIRVHTVVD-RPQQPMTHRETAPVSQPENKPESKPGPVGP 330
GA G + P + R Q M + + Q P++ G
Sbjct: 2196 GAGPGIGPGMANHNQFQQPQGVGYPPQQQQRMQHHMQQMQQGNMGQIGQLPQALGAEAGA 2255
Query: 331 ELPPGHIPIQVIRKEVDSKPVSQKPPPPSEKV---EVKVP-----------------PAP 370
L Q + ++ PV P P + + + + P P P
Sbjct: 2256 SLQAYQ---QRLLQQQMGSPVQPNPMSPQQHMLPNQAQSPHLQGQQIPNSLSNQVRSPQP 2312
Query: 371 VPCPPPSPGPSAVPSSPKSVATEERAAPSTAPAEATPPKPG--EAEAPPKHPG 421
VP P P P P S S + + +P + + P PG A+A P G
Sbjct: 2313 VPSPRPQSQP---PHSSPSPRMQPQPSPHHVSPQTSSPHPGLVAAQANPMEQG 2362
Score = 36.2 bits (82), Expect = 0.084
Identities = 36/133 (27%), Positives = 50/133 (37%), Gaps = 21/133 (15%)
Query: 290 PSPIRVHTVVDRPQQPMTHRETAPVSQPENKPESKPGPVGPELPPGHIPIQVIRKEVDSK 349
PSP QQP T + P SQP+ P P + P LP + +
Sbjct: 1848 PSPTPATPTTPTGQQPTTPQTPQPTSQPQPTP---PNSMPPYLP----------RTQAAG 1894
Query: 350 PVSQKPPPPSEKVEVKVPPAPVPCPPPSPGPSAVPSSPKSVATEERAAPSTAPAEATP-- 407
PVSQ +V P P PP PGP P++ + +RAA +
Sbjct: 1895 PVSQ----GKAAGQVTPPTPPQTAQPPLPGPP--PAAVEMAMQIQRAAETQRQMAHVQIF 1948
Query: 408 PKPGEAEAPPKHP 420
+P + + PP P
Sbjct: 1949 QRPIQHQMPPMTP 1961
Score = 31.6 bits (70), Expect = 2.1
Identities = 39/181 (21%), Positives = 58/181 (32%), Gaps = 26/181 (14%)
Query: 257 PRPLRAASPFRSSVQGASSREGSPARSSTPLHSPSPIRVHTVVDRPQQPMTHRETAPVSQ 316
PR A + G + P + PL P P V + + T R+ A V
Sbjct: 1888 PRTQAAGPVSQGKAAGQVTPPTPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQI 1947
Query: 317 PENKPESKPGPVGPELPPGHIPIQVIRKEVDSKPVSQKPPP----PSEKVEVKVPPAPVP 372
+ P+ ++PP P+ PPP PS +E + P +
Sbjct: 1948 FQR-------PIQHQMPP----------MTPMAPMGMNPPPMTRGPSGHLEPGMGPTGMQ 1990
Query: 373 CPPP-----SPGPSAVPSSPKSVATEERAAPSTAPAEATPPKPGEAEAPPKHPGVLKVEA 427
PP P P + S A A A P G+ P PG + +A
Sbjct: 1991 QQPPWSQGGLPQPQQLQSGMPRPAMMSVAQHGQPLNMAPQPGLGQVGISPLKPGTVSQQA 2050
Query: 428 I 428
+
Sbjct: 2051 L 2051
Score = 30.0 bits (66), Expect = 6.0
Identities = 69/326 (21%), Positives = 106/326 (32%), Gaps = 51/326 (15%)
Query: 59 PKETPSSANGPSREGSRLP----PAREGHPVYPQLRPGYIP----IPVLHEGAENRQVHP 110
P TP++ P+ + P P + P P P Y+P + +G QV P
Sbjct: 1848 PSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAAGQVTP 1907
Query: 111 FHVYPQPGMQRFRTEAAAAAPQRSQSPLRGMPETTQPDKQCGQVAAAAAAQPPASH---- 166
P P PQ +Q PL G P + Q+ AA Q +H
Sbjct: 1908 ----PTP-------------PQTAQPPLPGPPPAAV--EMAMQIQRAAETQRQMAHVQIF 1948
Query: 167 -GPERSQSPAASDCSSSSSSASLPSSGRSS--------LGSHQLP---RGYISIPVIHEQ 214
P + Q P + + + + G S G Q P +G + P +
Sbjct: 1949 QRPIQHQMPPMTPMAPMGMNPPPMTRGPSGHLEPGMGPTGMQQQPPWSQGGLPQPQQLQS 2008
Query: 215 NVTRPAAQPSFHQAQKTHYPAQQGEYQTH----QPVYHKIQGDDWEPRPLRAASPFRSSV 270
+ RPA Q + Q G Q +P Q R LR+ S
Sbjct: 2009 GMPRPAMMSVAQHGQPLNMAPQPGLGQVGISPLKPGTVSQQALQNLLRTLRSPSSPLQQQ 2068
Query: 271 QGASSREGSPARSSTPLHSPSPIRVHTVVDRPQQPMTHRETAPVSQPENKPESKPGPVGP 330
Q S +P + + R + QP+ + P QP +P + PG G
Sbjct: 2069 QVLSILHANPQLLAAFIKQ----RAAKYANSNPQPIPGQPGMPQGQPGLQPPTMPGQQGV 2124
Query: 331 ELPPGHIPIQVIRKEVDSKPVSQKPP 356
P + ++ V + Q+ P
Sbjct: 2125 HSNPAMQNMNPMQAGVQRAGLPQQQP 2150
>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
Length = 1094
Score = 67.0 bits (162), Expect = 4e-11
Identities = 97/399 (24%), Positives = 138/399 (34%), Gaps = 41/399 (10%)
Query: 59 PKETPSSANGPSREGSRLPPAREGHPVYPQLRPG-YIPIPVLHEGAENRQVHPFHVYPQ- 116
P P + + G +P G P P+ + +P P G+E P P
Sbjct: 497 PPPPPRRTHSLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPTTGGSEGAGAAPCPPNPAN 556
Query: 117 ---PGMQRFRTEAAAAAPQRSQSPLRGMPE-----TTQPDKQCGQVAAAAAAQPPASHGP 168
PG+ + +P+R+ SP G T P G A+ AQPP
Sbjct: 557 SWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPKPERV 616
Query: 169 ERSQSPAASD-------CSSSSSSASLPSSGRSSLGSHQLPRGYISIPVIHEQNVTRPAA 221
+SP AS CSSSS A SG L P G + H + +
Sbjct: 617 TSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQIL----TPLGDRFVIPPHPKVPAPFSP 672
Query: 222 QPSFHQAQKTHYPAQQGEYQTHQPVYHKIQGDDWEPRPLRAASPFRSSVQGASSREGSPA 281
PS ++ PA PV P P +P + S S++ SP
Sbjct: 673 PPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESP--VISKDQSPP 730
Query: 282 RSSTPLHSPSPI---RVHTVVDRPQQPMTHRETAPVSQPENKPESKPGPVGPEL------ 332
S P + P P + VV+ P T E P+ P P P P +L
Sbjct: 731 PSPPPSYHPPPPPTKKPEVVVEAPSASETAEE--PLQDPNWPPPPPPAPEEQDLSMADFP 788
Query: 333 PPGHIPIQVIRKEV-----DSKPVSQKPPPPSEKVEVKVPPAPVPCPPPSP-GPSAVPSS 386
PP V E + VS S +++ P P PPP+P P+ S+
Sbjct: 789 PPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPASSA 848
Query: 387 PKSVATEERAAPSTAPAEATPPKPGEAEAPPKHPGVLKV 425
P VA + P PP+ + AP P +L++
Sbjct: 849 PGHVAKLPQKEPVGCSKGGGPPRE-DVGAPLVTPSLLQM 886
Score = 44.7 bits (104), Expect = 2e-04
Identities = 76/345 (22%), Positives = 117/345 (33%), Gaps = 58/345 (16%)
Query: 134 SQSPLRGMPETTQPDKQCGQVAAAAAAQPPASHGPERSQSPAASDCSSSSSSASLPSSGR 193
S+ G PE++ A+ + PP G R SP+ + +S + S+ SSG+
Sbjct: 434 SKGGSEGQPESS---------TASNSVVPPPQGGSGRG-SPSGGSTAEASDTLSIRSSGQ 483
Query: 194 SSLGS----------------HQLPRGYISIPVIHEQNVTRPAAQPSFHQAQKTHYPAQQ 237
S S H L + +++P + + P Q Q P
Sbjct: 484 LSGRSVSLRKLKRPPPPPRRTHSLHQRGLAVP---DGPLGLPPKPERKQQPQLPRPPTTG 540
Query: 238 GEYQTHQPVYHKIQGDDWEP--------RPLRAASPFRSSVQGASSREGSPA-------- 281
G + W P RP R+ S G SS+ G+P
Sbjct: 541 GSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAG 600
Query: 282 --RSSTPLHSPSPIRVHTVVDRPQQPMTHRETAPVSQPENKPESKPGP-----VGPELP- 333
S P P RV ++ + + S + P + GP +G
Sbjct: 601 PPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVI 660
Query: 334 PGHIPIQVIRKEVDSKPVSQKPPPPSEKVEVKVPPAPVPCPPPSPGPSAVPSSPKSVATE 393
P H + SKP S P P+ VP PV SP P +P++ T
Sbjct: 661 PPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVP-GPVSTTDASP---QSPPTPQTTLTP 716
Query: 394 ERAAPSTAPAEATPPKPGEAEAPPKHPGVLKVEAILEKVQGLEQA 438
+ +P + ++ PP P + PP P K E ++E E A
Sbjct: 717 LQESPVISKDQSPPPSPPPSYHPPP-PPTKKPEVVVEAPSASETA 760
Score = 41.2 bits (95), Expect = 0.003
Identities = 99/450 (22%), Positives = 144/450 (32%), Gaps = 106/450 (23%)
Query: 11 QVASGNGDRDPLPPGWEIK--IDPQTGWPFFVDHNSRTTTWNDPRVPSEGPKETPSSANG 68
Q+ + GDR +PP ++ P P N P V T +S
Sbjct: 649 QILTPLGDRFVIPPHPKVPAPFSPPPSKPR--SPNPAAPALAAPAVVPGPVSTTDASPQS 706
Query: 69 PSREGSRLPPAREGHPVYPQLRPGYIPIPVLHEGAENRQVHPFHVYPQPGMQRFRTEAAA 128
P + L P +E + P P P +H P P + A
Sbjct: 707 PPTPQTTLTPLQESPVISKDQSPPPSPPP------------SYHPPPPPTKKPEVVVEAP 754
Query: 129 AAPQRSQSPLR-----------------GMPETTQPDKQCGQVAAAAAAQPPASHGPERS 171
+A + ++ PL+ M + P++ VA+ A P S PE
Sbjct: 755 SASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGS--PELV 812
Query: 172 QSPAASDCSSSSSSASLPSSG-----------RSSLGSH------QLPRGYISIPVIHEQ 214
SPAAS S+++ P S SS H + P G +
Sbjct: 813 SSPAASSSSATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPRE 872
Query: 215 NVTRPAAQPSFHQAQKTHYPAQQGEYQTHQPVYHKIQGDDWEPRPLRAASPFRSSVQGAS 274
+V P PS Q + G T G +PLR A R+S
Sbjct: 873 DVGAPLVTPSLLQMVRLRSVGAPGGAPT------PALGPSAPQKPLRRALSGRAS----- 921
Query: 275 SREGSPARSSTPLHSPSPIRVHTVVDRPQQPMTHRETAPVSQPENKPESKPGPVGPELPP 334
P+ +PS +H V + E +QP PE++P P P+ P
Sbjct: 922 -----------PVPAPSS-GLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRP--PQSPA 967
Query: 335 ---------GHIPIQVIRKE-------------VDSKPVSQKPPPPSEKVEVKVPPAPVP 372
G +Q+ R + + +S++ PP + K K PP
Sbjct: 968 STASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVAR 1027
Query: 373 CPPPSPGPSAVPSSPKSVATEERAAPSTAP 402
P P A PS P RA P TAP
Sbjct: 1028 KPSVGVPPPASPSYP-------RAEPLTAP 1050
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 66.2 bits (160), Expect = 8e-11
Identities = 97/386 (25%), Positives = 129/386 (33%), Gaps = 57/386 (14%)
Query: 59 PKETPSSANGPSREGSRLPPAR-----EGHPVYPQLRPGYIPIPVLHEGAENRQVHPFHV 113
PK P+S PS +G+ PPA +G P P P + P P P
Sbjct: 927 PKGIPAS---PSPKGAPTPPAATPPSPKGGPATPS--PKWAPTP------------PAAT 969
Query: 114 YPQPGMQRFRTEAAAAAPQRSQSPLRGMPETTQPDKQCGQVAAA--AAAQPPASHGPERS 171
P P + A +P+ + +P P T P + G + A PPA P
Sbjct: 970 PPSP-----KGGPATPSPKGAPTP----PAATPPSPKGGPATPSPKGAPTPPAVTPPSPK 1020
Query: 172 QSPAASDCSSSSSS--ASLPSSGRSSLGSHQLPRGYISIPVIHEQNVTRPAAQPSFHQAQ 229
SPAA+ +S+ A+ P S + S + LP+G + P + A PS A
Sbjct: 1021 GSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAP 1080
Query: 230 KTHY---PAQQGEYQTHQPVYHKIQGDDWEPRPLRAASPFRSSVQGASSREGSPARSSTP 286
P+ +G T P P P A P +G+P +TP
Sbjct: 1081 TPPAATPPSPKGGPATPSP--------KGAPMPPAATPPSPKGGLATPPHKGAP---TTP 1129
Query: 287 LHSPSPIRVHTVVDRPQQPMTHRETAPVSQPEN--KPESKPGPVGPELPPGHIPIQVIRK 344
+P + P+ T P S P K P P P +
Sbjct: 1130 AATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATP 1189
Query: 345 EVDSKPVSQKPPPPSEKVEVKVP-----PAPVPCPPPSPGPSAVPSSPKSVATEERAAP- 398
P + PPS K + P P PPSP SPK T A P
Sbjct: 1190 SPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPP 1249
Query: 399 STAPAEATPPKPGEAEAPPKHPGVLK 424
S ATPP G P P LK
Sbjct: 1250 SPKGGPATPPPKGAPTPPAATPPSLK 1275
Score = 63.9 bits (154), Expect = 4e-10
Identities = 93/381 (24%), Positives = 133/381 (34%), Gaps = 41/381 (10%)
Query: 52 PRVPSEGPKETPSSANGPSREGSRLPPAREGHPVYPQLRPGYIPIPVLHEGAENRQVHPF 111
P PS TP +A PS +G P+ +G P P P + P
Sbjct: 954 PATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPA 1013
Query: 112 HVYPQPGMQRFRT---EAAAAAPQRSQSPLRGMPETTQPDKQCGQVAAAAAAQP---PAS 165
P P T + A+ P + +G P T K AA P PA+
Sbjct: 1014 VTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPAT 1073
Query: 166 HGPERSQSPAASDCSSSSSSASLPSSGRSSL---GSHQLPRGYISIPVIHEQNVTRPAAQ 222
+ + +P A+ S + PS + + + P+G ++ P H+ T PAA
Sbjct: 1074 PSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPP-HKGAPTTPAAT 1132
Query: 223 PSFHQAQKTHYPAQQGEYQTHQPVYHKIQGDDWEPRPLRAASPFRSSVQGASSREGSPAR 282
P P+ +G T P +G P AA+P S +G +
Sbjct: 1133 P----------PSPKGGLATPPP-----KGAPTTP----AATP--PSPKGGLATPPPKGA 1171
Query: 283 SSTPLHSPSPIRVHTVVDRPQQPMTHRETAPVSQPEN--KPESKPGPVGPELPPGHIPIQ 340
+TP +P + P+ T P S P K P P P
Sbjct: 1172 PTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGG 1231
Query: 341 VIRKEVDSKPVSQKPPPPSEKVEVKVPPAPVPCPPPSPGPSAVPSSPKSVAT-EERAAPS 399
+ P + PPS K P P P P+P + PS +AT + AP+
Sbjct: 1232 LATPSPKGAPTTPAATPPSPK---GGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPN 1288
Query: 400 TAPAEATPPKP--GEAEAPPK 418
PA TPP P G A +PPK
Sbjct: 1289 --PAVVTPPSPKGGPATSPPK 1307
Score = 63.2 bits (152), Expect = 6e-10
Identities = 104/400 (26%), Positives = 134/400 (33%), Gaps = 74/400 (18%)
Query: 52 PRVPSEGPKETPSSANGPSREGSRLPPAREGHPVYPQLRPGYIPIPVLHEGAENRQVHPF 111
P PS TP +A PS +G P+ +G P P + P P P A
Sbjct: 977 PATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTP---PSPKGSPAAT------- 1026
Query: 112 HVYPQPGMQRFRTEAAAAAPQRSQSPL-----RGMPET---TQPDKQCGQVAAA--AAAQ 161
P + T AA P SP +G P T T P + G + A
Sbjct: 1027 -----PFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPT 1081
Query: 162 PPASHGPERSQSPAASDCSSSSSSASLPSSGRSSLGSHQLPRGYISIPVIHEQNVTRPAA 221
PPA+ P SP + S A +P + + P+G ++ P H+ T PAA
Sbjct: 1082 PPAATPP----SPKGGPATPSPKGAPMPPAA-----TPPSPKGGLATPP-HKGAPTTPAA 1131
Query: 222 QPSFHQAQKTHYPAQQGEYQTHQPVYHKIQGDDWEPRPLRAAS------PFRSSVQGASS 275
P + P +G T +G P P A + P S
Sbjct: 1132 TPPSPKGGLAT-PPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPS 1190
Query: 276 REGSPAR-SSTP------LHSPSPIRVHTV-VDRPQQPMTHRET-----APVSQPENKPE 322
+G+P ++TP L +PSP T P P T AP + P
Sbjct: 1191 PKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPS 1250
Query: 323 SKPGPVGPELPPGHIPIQVIRKEVDSKPVSQKPPPPSEKVEVKVPP---APVPC--PPPS 377
K GP P PP P PPS K + PP AP P PPS
Sbjct: 1251 PKGGPATP--PP------------KGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPS 1296
Query: 378 PGPSAVPSSPKSVATEERAAPSTAPAEATPPKPGEAEAPP 417
P S PK T A P + P P A PP
Sbjct: 1297 PKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPP 1336
Score = 62.0 bits (149), Expect = 1e-09
Identities = 103/413 (24%), Positives = 141/413 (34%), Gaps = 33/413 (7%)
Query: 32 PQTGWPFFVDHNSRTTTWNDPRVPSEGPKETPSSANGPSREGSRLPPAREGHP-----VY 86
P+ F +S TT + P PS TPS+ S +G LPP P +
Sbjct: 837 PENSLSFQGSKDSPATT-HSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPF 895
Query: 87 PQLRPGYIPIPVLHEGAENRQVHPFHVYPQP---GMQRFRTEAAAAAPQRSQSPL-RGMP 142
P+ P P P P P G+ + A P + P +G P
Sbjct: 896 PKEGPA-TPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGP 954
Query: 143 ETTQPDKQCGQVAAAAAAQP---PASHGPERSQSPAASDCSSSSSSASLPS---SGRSSL 196
T P K AA P PA+ P+ + +P A+ S + PS +
Sbjct: 955 ATPSP-KWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPA 1013
Query: 197 GSHQLPRGYISIPVIHEQNVTRPAAQPSFHQAQKTHYPAQQGEYQTHQPVYHKIQGDDWE 256
+ P+G + + T PAA P + P +G T +G
Sbjct: 1014 VTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPAT 1073
Query: 257 PRPLRAASPFRSSVQGASSREGSPARSSTPLHSPSPIRVHTVVDRPQQPMTHRETAPVSQ 316
P A +P ++ S +G PA S P +P P + + AP +
Sbjct: 1074 PSLKGAPTPPAAT---PPSPKGGPATPS-PKGAPMPPAATPPSPKGGLATPPHKGAPTTP 1129
Query: 317 PENKPESKPGPVGPELPPGHIPIQVIRKEVDSKPVSQKPPPP-SEKVEVKVPPAP----- 370
P K G P PP P K PPP + PP+P
Sbjct: 1130 AATPPSPKGGLATP--PPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLA 1187
Query: 371 VPCPPPSP-GPSAVPSSPK-SVATEERAAPSTAPAEATPPKPGEAEAPPKHPG 421
P P +P P+A P SPK +AT T PA ATPP P A P G
Sbjct: 1188 TPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPA-ATPPSPKGGLATPSPKG 1239
Score = 60.5 bits (145), Expect = 4e-09
Identities = 91/379 (24%), Positives = 128/379 (33%), Gaps = 60/379 (15%)
Query: 55 PSEGPKETPSSANGPSREGSRLPPAREGHPVYPQLRP----GYIPIPVLHEGAENRQVHP 110
PS T +A PS +G P +G P P P G + P H+GA N
Sbjct: 1235 PSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPP-HKGAPN----- 1288
Query: 111 FHVYPQPGMQRFRTEAAAAAPQRSQSPLRGMPETTQPDKQCGQVAAAAAAQPPASHG--- 167
A P P T P K AA P S G
Sbjct: 1289 --------------PAVVTPPSPKGGP------ATSPPKGAPTPPAATPPSPKGSPGTPP 1328
Query: 168 PERSQSPAASDCSSSSSSASLPSSGRSSLGSHQLPRGYISIPVIHEQNVTRPAAQPSFHQ 227
P+ + +P A S + +LP++ SS G P ++ T PAA PS
Sbjct: 1329 PKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSS--------KEGPTPPAATPSHKG 1380
Query: 228 AQKTHYPAQQGEYQTHQPVYHKIQGDDWEPRPLRAASPFRSSVQGASSREGSPARSSTPL 287
PA P +GD P + SP ++ + REG+ S L
Sbjct: 1381 G-----PAMTPPSPKRGPAIPSPKGDPTSPAVI-PLSPKKAPATPVT-REGAATPSKGDL 1433
Query: 288 HSPSPIRVHTVVDRPQQPMTHRETAPVSQPENKPESKPGPVGPELPPGHIPIQVIRKEVD 347
P+ T V + P T +AP P P SK P P + P K+V
Sbjct: 1434 TPPAV----TPVSLKKAPAT---SAPKGGPAT-PSSKGDPTLPAVTPPSPKEPPAPKQVA 1485
Query: 348 SKPVSQKPPPPSEKVEVKVPPAPVPCPPP----SPGPSAVPSSPKSVATEERAAPSTAPA 403
+ +K P + PA +P P +P P +P + ++ + AP
Sbjct: 1486 TSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPK 1545
Query: 404 EATPPKPGEAEAPPKHPGV 422
EA P +P K P +
Sbjct: 1546 EALIPPAMTVPSPKKTPAI 1564
Score = 54.7 bits (130), Expect = 2e-07
Identities = 88/374 (23%), Positives = 124/374 (33%), Gaps = 80/374 (21%)
Query: 58 GPKETPSSANGPSREGSRLPPAREGH---PVYPQLRPGYIPIPVLHEGAENRQVHPFHVY 114
G +P + P+++GS P G+ PV P + ++P L H
Sbjct: 798 GVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSP-VEASFLPENSLSFQGSKDSPATTHS- 855
Query: 115 PQPGMQRFRTEAAAAAPQRSQSPLRGMPETTQPDKQCGQVAAAAAAQPPASHGPERSQSP 174
P P + +A P + ET P V + PA+ P+ Q+P
Sbjct: 856 PTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSV----VNLPFPKEGPATPAPK--QAP 909
Query: 175 AASDCSSSSSSASLPSSGRSSLGSHQLPRGYISIPVIHEQNVTRPAAQPSFHQAQKTHYP 234
A S SSS P R++ P+G + P + T PAA P P
Sbjct: 910 ALSMTSSS------PKKARAT----PAPKGIPASPS-PKGAPTPPAATP----------P 948
Query: 235 AQQGEYQTHQPVYHKIQGDDWEPRPLRAASPFRSSVQGASSREGSPARSSTPLHSPSPIR 294
+ +G T P W P P A P S +G PA S P +P+P
Sbjct: 949 SPKGGPATPSP--------KWAPTPPAATPP---------SPKGGPATPS-PKGAPTP-- 988
Query: 295 VHTVVDRPQQPMTHRETAPVSQPENKPESKPGPVGPELPPGHIPIQVIRKEVDSKPVSQK 354
P + P P K GP P P V P +
Sbjct: 989 ------------------PAATP---PSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATP 1027
Query: 355 PPPPSEKVEVKVPPAPVPCPPPSPGPSAVPSSPKSVATEERAAPST-------APAEATP 407
P + PP+P P +P P P++P + + P+T P ATP
Sbjct: 1028 FPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATP 1087
Query: 408 PKPGEAEAPPKHPG 421
P P A P G
Sbjct: 1088 PSPKGGPATPSPKG 1101
Score = 51.6 bits (122), Expect = 2e-06
Identities = 68/294 (23%), Positives = 105/294 (35%), Gaps = 19/294 (6%)
Query: 142 PETTQPDKQCGQVAAAAAAQPPASHGPERSQSPAASDCSSSSSSASLPSSGRSSLG--SH 199
P++ P + + AA P S P A S+ +++AS G SL +H
Sbjct: 629 PDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNH 688
Query: 200 QLPRGYIS-IPVIHEQNVTRPAAQPSFHQAQKTHYPAQQGEYQTHQPVYHKIQGDDWEPR 258
+ G ++ +P++ + P A PS Q T P P +
Sbjct: 689 PVKEGTLTTLPLVPTASENCPVA-PS---PQNTCAPLATLVLAPEIP-----KSVPSPSL 739
Query: 259 PLRAASPFRSSVQGASSREGSPARSSTPLHSPSPIRVHTVVDRPQQPMTHRETAP----- 313
P P V G S +S+P P+ + + +T+ +P
Sbjct: 740 PPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGV 799
Query: 314 -VSQPENKPESKPGPVGPELPPGHIPIQVIRKEVDSKPVSQKPPPPSEKVEVKVPPAPVP 372
VS +P +K G GP+ P G++ V E P + S+ P
Sbjct: 800 SVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPP 859
Query: 373 CPPPSPGPSAV-PSSPKSVATEERAAPSTAPAEATPPKPGEAEAPPKHPGVLKV 425
P +P PSAV P SPK V + P+ + PK G A PK L +
Sbjct: 860 SPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSM 913
Score = 50.1 bits (118), Expect = 6e-06
Identities = 90/407 (22%), Positives = 138/407 (33%), Gaps = 50/407 (12%)
Query: 55 PSEGPKETPSSANGPSREGSRLPPAREGHPVYPQLRPGYIPIPVLHEGAENRQVHPFHVY 114
P +G TP+ A PS +G P +G P P P + + P
Sbjct: 1121 PHKGAPTTPA-ATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATP 1179
Query: 115 PQP--GMQRFRTEAAAAAPQRSQSPLRGMPETTQPDKQCGQVAAAAAAQPPASHGPERSQ 172
P P G+ + A P + +G T P AA PP+ G +
Sbjct: 1180 PSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKG----APTTPAATPPSPKGGLATP 1235
Query: 173 SPAASDCSSSSSSASLPSSGRSSLGSHQLPRGYISIPVIHEQNVTRPAAQPSFHQAQKTH 232
SP + + +++ S P G ++ P + P + + P + + + A T
Sbjct: 1236 SPKGAPTTPAATPPS-PKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTP 1294
Query: 233 YPAQQGEYQTHQPVYHKIQGDDWEPRPLRAASPFRSSVQGASSREGSPARSSTPLHSP-- 290
P+ +G T P P P A P G +G+P + SP
Sbjct: 1295 -PSPKGGPATSPP--------KGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKG 1345
Query: 291 SPIRVHTVVDRPQQPMTHRETAPVSQPENKPESKPGPV--------GPELP--------P 334
+P T P T + P P K GP GP +P P
Sbjct: 1346 TPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSP 1405
Query: 335 GHIPIQVIRKEVDSKPVSQKPPPPSEKVEVKVPPAPVPCP----PPSPGPSAVPSSPKSV 390
IP+ K+ + PV+++ K ++ PPA P P + P P++P S
Sbjct: 1406 AVIPLSP--KKAPATPVTREGAATPSKGDL-TPPAVTPVSLKKAPATSAPKGGPATPSSK 1462
Query: 391 ATEERAA-----PSTAPAE---ATPPKPGEAEAPPKHPGVLKVEAIL 429
A P PA AT P +A A P G + A++
Sbjct: 1463 GDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVI 1509
Score = 50.1 bits (118), Expect = 6e-06
Identities = 80/369 (21%), Positives = 117/369 (31%), Gaps = 48/369 (13%)
Query: 52 PRVPSEGPKE--TPSSANGPSREGSRLPPAREGHPVYPQLRPGYIPIPVLHEGAENRQVH 109
P V S PKE TP + PS E PA +G P P PV ++
Sbjct: 1603 PAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSP---------PVTPSSLKDSPTS 1653
Query: 110 PFHVYPQPGMQRFRTEAAAAAPQRSQSPLRGMPETTQPDKQCGQVAAAAAAQPPASHGPE 169
P V + G A PQ S +G+P P + A A P P
Sbjct: 1654 PASVTCKMG---------ATVPQAS----KGLPAKKGPTALKEVLVAPAPESTPIITAPT 1700
Query: 170 RSQSPAASDCSSSSSSASLPSSGRSSLGSHQLPRGYISIPVIHEQNVTRPAAQPSFHQAQ 229
R ++S PS+ S G +PV + + T S
Sbjct: 1701 RKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKG 1760
Query: 230 KTHYPAQQGEYQTHQPVYHKIQGDDWEPRPLRAASPFRSSVQGASSREGSPARSSTPLHS 289
P + + K+ P+P A+ S + SP + P
Sbjct: 1761 PLAPPESKASTPLTAAAFEKVL-----PKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQ 1815
Query: 290 PSPIRVHTVVDRPQQPMTHRETAPVSQPENKPESKPGPVGPELPPGHIPIQVIRKEVDSK 349
P V++ P +P+ AP + E P P P+ G +P Q +
Sbjct: 1816 FLPSSPGLVLESPSKPL-----APADEDELLPLIPPEPIS-----GGVPFQSV------- 1858
Query: 350 PVSQKPPPPSEKVEVKVPPAPVPCPPPSPGPSAVPSSPKSV-ATEERAAPSTAPAEATPP 408
+ P P S + V P A P + G S +SV EE+ + +A
Sbjct: 1859 -LVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQATTQQAQLA 1917
Query: 409 KPGEAEAPP 417
E + P
Sbjct: 1918 AAAEIDEEP 1926
Score = 43.5 bits (101), Expect = 5e-04
Identities = 86/396 (21%), Positives = 123/396 (31%), Gaps = 93/396 (23%)
Query: 59 PKETPSSANGP----SREGSRLPPAREGHPVYPQLRPGYIP----IPVLHEGAENRQVHP 110
P TPSS GP S+EG P A H P + P IP + V P
Sbjct: 1350 PATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIP 1409
Query: 111 FHVYPQPGMQRFRTEAAAAA------PQRSQSPLRGMPETTQPDKQCGQVAAAAAAQP-- 162
P R AA + P + L+ P T+ P + G ++ P
Sbjct: 1410 LSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAP--KGGPATPSSKGDPTL 1467
Query: 163 PASHGPERSQSPAASDCSSSSSSASLPSSGRSSLGSHQLPRGYISIPVIHEQNVTRPAAQ 222
PA P + PA ++SSS P++ P G ++P + + A
Sbjct: 1468 PAVTPPSPKEPPAPKQVATSSSPKKAPAT--------PAPMGAPTLPAVIPSSPKEVPAT 1519
Query: 223 PSFHQAQKTHYPAQQGEYQTHQPVYHKIQGDDWEPRPLRAASPFRSSVQGASSREGSPAR 282
PS + P+ +P + + + +P
Sbjct: 1520 PSSRR----------------DPI-----------------APTATLLSKKTPATLAPKE 1546
Query: 283 SSTP--LHSPSPIRVHTVVDRPQQPMTHRETAPVSQPENKPESKPGPVGPELPPGHIPIQ 340
+ P + PSP + + + P T S P P + G P
Sbjct: 1547 ALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSP---------- 1596
Query: 341 VIRKEVDSKPVSQKPPPPSEKVEVKVPPAPVPCPPPSPGPSAVPSSPKSVATEERAAPS- 399
KE+ P P P K P P PPSP +PK T PS
Sbjct: 1597 ---KELLIPPAVTSPSP-------KEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSS 1646
Query: 400 -----TAPAE------ATPPKPGEAEAPPKHPGVLK 424
T+PA AT P+ + K P LK
Sbjct: 1647 LKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALK 1682
Score = 35.0 bits (79), Expect = 0.19
Identities = 34/134 (25%), Positives = 50/134 (37%), Gaps = 10/134 (7%)
Query: 279 SPARSSTPLHSPSPIRVHTVVDRPQQPMTHRETAPVSQPENKPESKPGPVGPELPPGHIP 338
S A ++P SPS I T ++ P + P+ P P +GP + P +
Sbjct: 59 SAANQASPFPSPSTI-ASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALA 117
Query: 339 IQ--VIRKEVDSKPVSQKPPPPSEKVEVKVPPAPVPCPPPSPGPSAVPSSPKSVATEERA 396
+ +I + P S P V AP S P + +SP SVA E
Sbjct: 118 LASPMIAPTLKGTPSSSAPL-------ALVALAPHSVQKSSAFPPNLLTSPPSVAVAESG 170
Query: 397 APSTAPAEATPPKP 410
+ T A P +P
Sbjct: 171 SVITLSAPIAPSEP 184
Score = 32.7 bits (73), Expect = 0.93
Identities = 51/208 (24%), Positives = 80/208 (38%), Gaps = 24/208 (11%)
Query: 279 SPARSSTPLHSPSPIRVHTVVDRP---QQPMTHRETA---PVSQPENKPE---SKPGPVG 329
SP SS P+ + P +V P ++P T T PVS P PE + P V
Sbjct: 464 SPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVL 523
Query: 330 PELPPGHIPIQVIRKEVDSKPVSQKPPPPSEKVEVKVPPAPVPCPPPSPGPSAVPSSPKS 389
+ P +Q + ++ P S + K + V P P SP + SSP+
Sbjct: 524 VKFPTQK-DLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEI 582
Query: 390 VATEERAAPSTAPAEATP-PKPGEAEAPPKHPGVLKVEAILEKVQGLEQAVDNFEGKKTD 448
+ E + E P KP + P GV ++++ D++ G +
Sbjct: 583 PLSPEATLAKKSLGEPLPIGKPASSMTSPL--GVNSSASVIK--------TDSYAGPDSA 632
Query: 449 KKYLMIEEYLTKELLA--LDSVDPEGRA 474
L+ +T + A L+S DP G A
Sbjct: 633 GP-LLKSSLITPTVAAFPLESADPAGVA 659
Score = 31.2 bits (69), Expect = 2.7
Identities = 24/85 (28%), Positives = 31/85 (36%), Gaps = 18/85 (21%)
Query: 349 KPVSQKPPPPSEKVEVKVPPAPVPCP-------PPSPGPSAVPSSPKSVATEERAAPSTA 401
+P PPP S PAP CP P P PS + S+P V + ++ +
Sbjct: 40 QPGPTLPPPCS--------PAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQSSSGTAL 91
Query: 402 PAEATPPKP---GEAEAPPKHPGVL 423
P P P PP P L
Sbjct: 92 PLGTAPEAPTFLPNLIGPPISPAAL 116
Score = 30.4 bits (67), Expect = 4.6
Identities = 54/202 (26%), Positives = 75/202 (37%), Gaps = 34/202 (16%)
Query: 257 PRPLRAAS-----PFRSSVQGASSREGSPARSST-------PLHSPSPIRVHTVVDRPQQ 304
P P AS PF S G + G+ + T P SP+ + + + + P
Sbjct: 68 PSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIAPTL 127
Query: 305 PMTHRETAPVSQPENKPES--KPGPVGPELPPGHIPIQVIRKEVDSKPVSQKPPPPSE-K 361
T +AP++ P S K P L P V E S P PSE K
Sbjct: 128 KGTPSSSAPLALVALAPHSVQKSSAFPPNLLTS--PPSVAVAESGSVITLSAPIAPSEPK 185
Query: 362 VEV-KVPPAPVPCPPPSPGP----SAVP--------SSPKSVATEERAAPSTAPAEATPP 408
+ KVP VP P +P P S VP S VA+ + P+T A A+P
Sbjct: 186 TNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQ 245
Query: 409 KP----GEAEAPPKHPGVLKVE 426
P++PG L ++
Sbjct: 246 VKDTTISSVLISPQNPGSLSLK 267
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 65.5 bits (158), Expect = 1e-10
Identities = 104/428 (24%), Positives = 161/428 (37%), Gaps = 68/428 (15%)
Query: 1 MSAATHSPMMQVASGNGDRDPLPPGWEIKIDPQTGWPFFVDHNSRTTTWNDPRVPSEGPK 60
+++A +P + A+ R PL +E ++ +T P SRT P PS+
Sbjct: 2366 LTSARMAPALSGANLTSPRVPLS-AYE-RVSGRTSPPLLDRARSRTP----PSAPSQSRM 2419
Query: 61 ET-----PSSANGPSREGSRLPPAREGHPVYPQLRPGYIPIPVLHEGAENRQVHPFHVYP 115
+ PSS G + S LPPA++ Q R PV ++ + P
Sbjct: 2420 TSERAPSPSSRMGQAPSQSLLPPAQD------QPRS-----PVPSAFSDQSRCLIAQTTP 2468
Query: 116 QPGMQRFRTEAAAAAPQRS--QSPLRGMPETTQPDKQCGQVAAAAAAQPPAS-----HGP 168
G Q + A A + + + +P P G+ A+ AQ P++
Sbjct: 2469 VAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAK 2528
Query: 169 ERSQSPAASDCSSSSSSASLPSSGRSSLGSHQLPRGYISIPVIHEQNVTR-PAAQPSFHQ 227
ER S ++S SSSSSS+S SS SS GS S+PV E + R P+ P+ +
Sbjct: 2529 ERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKE 2588
Query: 228 AQKTHYPAQQGEYQTHQPVYHKIQGDDWEPRPLRAASPFRSSVQGASSREGSPARSSTPL 287
A + P P P A RSS +SS S + SS+
Sbjct: 2589 AVREGRP----------------------PEPTPAKRKRRSSSSSSSSSSSSSSSSSSSS 2626
Query: 288 HSPSPIRVHTVVDRPQQPMTHRETAPVSQPENKPESKPGPVGPELPP-----GHIPIQVI 342
S S + + ++ S + P++ P P P+ PP P + I
Sbjct: 2627 SSSS----SSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPI 2682
Query: 343 RKEVDSKPVSQKPPPPSEKVEVKVPPAPVPCPPPSPGPSAVPSSPKSVATEERAAPSTAP 402
DS+ +S P VE + P+P P P S+ S + + R+
Sbjct: 2683 DSLRDSRSLSYSP------VE-RRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRR 2735
Query: 403 AEATPPKP 410
E P+P
Sbjct: 2736 RETPSPRP 2743
Score = 56.2 bits (134), Expect = 8e-08
Identities = 74/319 (23%), Positives = 125/319 (39%), Gaps = 44/319 (13%)
Query: 119 MQRFRTEAAAAAPQRSQSPLRGMPETTQPDKQCGQVAAAAAAQPPASHGPERSQSPAASD 178
++R + ++ Q+SQ+P R + K + + + ++S++P+
Sbjct: 775 LRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQS 834
Query: 179 CSSSSSSASLPSSGRSSLGSHQLPRGYISIPVIHEQNVTRPAAQPSFHQAQKTHYPAQQG 238
SSSS + S GS I+ P +EQ+VT P + F +
Sbjct: 835 HSSSSPHPKVKSGTPPRQGS-------ITSPQANEQSVT-PQRRSCFESSPDP------- 879
Query: 239 EYQTHQPVYHKIQGDDWEPRPLRAASPFRSSVQGASSREG------SPA-RSSTPLHSPS 291
E ++ P H G P +++++P R S +SS + SP RS + SPS
Sbjct: 880 ELKSRTPSRHSCSGSS--PPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPS 937
Query: 292 PIRVHTVVDRPQQPMTHRETAPVSQPENKPESKPGPVGPELPPGHIPIQVIRKEVDSKPV 351
P RV + P R +P S E++ + G P + + ++ S +
Sbjct: 938 PSRVTSRTT----PRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSI 993
Query: 352 SQKPPPPSEKVEVKVPPAPV------PCPPPSPGPSAVPSSPKSVATEERAAPSTAPAE- 404
S P KV+ + PP P PCP S V S P S++ ST P E
Sbjct: 994 SPYP-----KVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGES 1048
Query: 405 ----ATPPKPGEAEAPPKH 419
++ G+++ P H
Sbjct: 1049 YFGVSSLQLKGQSQTSPDH 1067
Score = 46.2 bits (108), Expect = 8e-05
Identities = 58/269 (21%), Positives = 98/269 (36%), Gaps = 21/269 (7%)
Query: 157 AAAAQPPASHGPERSQSPAASDCSSSSSSASLPSSGRSSLGSHQLPRGYISIPVIHEQNV 216
A A+ PA P+ P + SSSS + P + + R S P +
Sbjct: 157 AREAKQPAPEPPK----PYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKS 212
Query: 217 TRPAAQPSFHQAQKTHYPAQQGEYQTHQPVYHKIQGDDWEPRPLRAASPFRSSVQGASSR 276
++ S +++K + + + + + + P P + +S ASS
Sbjct: 213 SKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSS 272
Query: 277 EGSPARSSTPLHSPSPIRVHT--VVDRPQQPMTHRE---TAPVSQPENKPESKPGPVGPE 331
+ S +RS + + + HT + R P + R AP S+P +P
Sbjct: 273 DTSRSRSRS-----AAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETA 327
Query: 332 LPPGHIPIQVIRKEVDSKPVSQKPPPPSEKVEVKVPPAPVPCPPPSPGPSAVPSSPKSVA 391
P + K+ K ++ P P PPAP P G S P + ++
Sbjct: 328 TKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLS 387
Query: 392 TEERAAPSTAPAEATPPKPGEAEAPPKHP 420
E P P+EA+P + +PPK P
Sbjct: 388 QE----PVNPPSEASPTRD---RSPPKSP 409
Score = 46.2 bits (108), Expect = 8e-05
Identities = 71/302 (23%), Positives = 103/302 (34%), Gaps = 21/302 (6%)
Query: 117 PGMQRFRTEAAAAAPQRSQSPLRGMPETTQPDKQCGQVAAAAAAQPPASHGPERSQSPAA 176
P + R R+ +AP +S+ P P + GQ A + + PPA P A
Sbjct: 2400 PLLDRARSRTPPSAPSQSRMTSERAPS---PSSRMGQ-APSQSLLPPAQDQPRSPVPSAF 2455
Query: 177 SDCSSSSSSASLPSSGRSSLGSHQLPRGYISIPVIHEQNVTRPAAQPSFHQAQKTHYPAQ 236
SD S + + P +G SL S + S H ++ PA P + PA
Sbjct: 2456 SDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGD-HNGMLSVPA--PGVPHSDVGEPPAS 2512
Query: 237 QGEYQTHQPVYHKIQGDDWEPRPLRAASPFRSSVQGASSREGSPARSSTPLHSPSPIRVH 296
G Q +P R +S SS +SS S + SS+ S S
Sbjct: 2513 TGAQQPSALAA-------LQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEG 2565
Query: 297 TVVDRPQQPMTHRETAPVSQPENKPESKPGPVGPELPPGHIPIQVIRKEVDSKPVSQKPP 356
+ + P QP + P P K + G PP P + R+ S S
Sbjct: 2566 SSL--PVQPEVALKRVPSPTPAPKEAVREGR-----PPEPTPAKRKRRSSSSSSSSSSSS 2618
Query: 357 PPSEKVEVKVPPAPVPCPPPSPGPSAVPSSPKSVATEERAAPSTAPAEATPPKPGEAEAP 416
S + S S+ SSP +A P A + PP + +P
Sbjct: 2619 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSP 2678
Query: 417 PK 418
K
Sbjct: 2679 RK 2680
Score = 42.0 bits (97), Expect = 0.002
Identities = 60/248 (24%), Positives = 91/248 (36%), Gaps = 39/248 (15%)
Query: 132 QRSQSPLRGMPETTQPDKQCGQVAAAAAAQPPASHGPERSQSPAASDCSSSSSSASL--- 188
++S+ R +T P + + + +A +S RS+S +A+ + +++ A
Sbjct: 238 RKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPS 297
Query: 189 PSSGRSSLGSHQLPRGYISIPVIHEQNVTRPAAQPSFHQAQKTHYPAQQGEYQTHQPV-- 246
P+SGR G P ++P Q+ P E T QP
Sbjct: 298 PASGRRGEGD-------------------APFSEPGTTSTQRPSSP----ETATKQPSSP 334
Query: 247 YHKIQGDDWEPRPLRAA-SPFRSSVQGASSREGSPARSSTPLHSPSPIRVHTVVDRPQQP 305
Y D E R + SP RSS G +P + SP P+ + P P
Sbjct: 335 YEDKDKDKKEKSATRPSPSPERSST-GPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNP 393
Query: 306 MTH----RETAPVSQPENKPESKPGPVGPELPPGHIPIQVIRKEVDSKPVSQKP-PPPSE 360
+ R+ +P PE P+S P P P +V R S P S KP P P
Sbjct: 394 PSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQ---PTKVSR-HASSSPESPKPAPAPGS 449
Query: 361 KVEVKVPP 368
E+ P
Sbjct: 450 HREISSSP 457
Score = 42.0 bits (97), Expect = 0.002
Identities = 41/158 (25%), Positives = 59/158 (37%), Gaps = 17/158 (10%)
Query: 273 ASSREG---SPARSSTPLHSPSPIRVHTVVDRPQQPMTHRETAPVSQPENKPESKP--GP 327
AS R G +P + P T +P P ++ + +P P
Sbjct: 299 ASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSS 358
Query: 328 VGPELPPGHIPIQVIR-----KEVDSKPVSQKP-PPPSEKVEVKVPPAPVPCPPPSPGPS 381
GPE PP P+ R + + + P+SQ+P PPSE P PP SP
Sbjct: 359 TGPE-PPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSE-----ASPTRDRSPPKSPEKL 412
Query: 382 AVPSSPKSVATEERAAPSTAPAEATPPKPGEAEAPPKH 419
SS +S + + A ++P P A AP H
Sbjct: 413 PQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSH 450
Score = 38.9 bits (89), Expect = 0.013
Identities = 83/370 (22%), Positives = 131/370 (35%), Gaps = 54/370 (14%)
Query: 2 SAATHSPMMQVASGNGDRD---PLPPGWEIKIDPQTGWPFFVDHNSRTTTWNDPRVPSEG 58
S ++ SP +V SG R P E + PQ S + DP + S
Sbjct: 834 SHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQ--------RRSCFESSPDPELKSRT 885
Query: 59 PKETPSSANGPSREGSRLP----PAREGHPVYPQLRPGYIPIPVLHEGAENRQVHPFHVY 114
P S + P R S P P+R P P+++ P H G+ + P V
Sbjct: 886 PSRHSCSGSSPPRVKSSTPPRQSPSRSSSP-QPKVKAIISPRQRSHSGSSSPS--PSRVT 942
Query: 115 PQPGMQRFRTEAAAA------APQRSQS-----PLRGMPETTQPDKQCGQVA--AAAAAQ 161
+ +R R+ + + P+ S S + PET G ++ AQ
Sbjct: 943 SRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQ 1002
Query: 162 PPASHGPERSQSPAASDCSSSSSSASLPSS-------------GRSSLGSHQLP-RGYIS 207
P S+SP + S S S P S G S G L +G
Sbjct: 1003 TPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQ 1062
Query: 208 IPVIHEQNVTRPAAQPSFHQA----QKTHYPAQQGEYQTHQPVYH-KIQGDDWEPRPLRA 262
H + + P + S ++ K+ + G ++ PV + + R +
Sbjct: 1063 TSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFS 1122
Query: 263 ASP-FRSSVQGASSREGSPARSSTPLHSPSPI---RVHTVVDRPQQPMTHRETAPVSQPE 318
ASP +S + SR S + S + S S + R+ T + + + +E A S P
Sbjct: 1123 ASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPR 1182
Query: 319 NKPESKPGPV 328
K + P PV
Sbjct: 1183 QKDKFSPFPV 1192
Score = 38.1 bits (87), Expect = 0.022
Identities = 101/477 (21%), Positives = 169/477 (35%), Gaps = 88/477 (18%)
Query: 13 ASGNGDRDP------LPPGWEIKIDPQTGWPFFVDHNSRTTTWNDPRVPSEGP-KETPSS 65
AS DR P LP + P + P V ++ ++ + P+ G +E SS
Sbjct: 397 ASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSS 456
Query: 66 ANGPSREGSRLPPAREGHPVYPQLRPGYIPIPVLHEGAENRQVHPF---HVYPQ-PGMQR 121
+R R + H P R G P + +R P H + P +R
Sbjct: 457 PTSKNRSHGRAKRDKS-HSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRR 515
Query: 122 FRTE---AAAAAPQR---SQSPLRGMPETTQPDKQCGQVAAA----AAAQPPASHGPERS 171
R+ + +PQR S+SP R ++ ++ G+ +A + ++ PA+ G RS
Sbjct: 516 SRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRS 575
Query: 172 QSPAASDCSSS-----------------SSSASLPSSGRSSLGSHQLPRGYISIPVIHEQ 214
++PA S S S S + GRS + R PV
Sbjct: 576 RTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRS 635
Query: 215 NVTRPAAQ--------PSFHQAQKTHYPAQQGEYQTHQPVYHKIQGDDWEP--------- 257
PA + P+ ++ PA++G ++ P + P
Sbjct: 636 RSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSR 695
Query: 258 RPLRAASPFRSSVQGASSREGSPAR-----SSTPLHSPSPI-----RVHTVVDRPQQPMT 307
P R S RS V+ S +P R SS+ + S R ++ + + ++
Sbjct: 696 TPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRIS 755
Query: 308 HRETAPVSQPENKPESKPGPVGPELPPGHIPIQVIRKEVDSKPV---SQKPPPPSEKVEV 364
R + +S P +K +S+ + + R S P + PP +
Sbjct: 756 SRRSRSLSSPRSKAKSR--------------LSLRRSLSGSSPCPKQKSQTPPRRSRSGS 801
Query: 365 KVPPAPVPCPP-PSPGPSAVPSSPKSVATEERAAPSTAP----AEATPPKPGEAEAP 416
P A PP S S+ P KS ++ S++P TPP+ G +P
Sbjct: 802 SQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSP 858
Score = 37.4 bits (85), Expect = 0.038
Identities = 84/396 (21%), Positives = 137/396 (34%), Gaps = 44/396 (11%)
Query: 40 VDHNSRTTTWNDPRVPSEGPKETPSSANGPSREGSRLPPA--REGHPVYPQLRPGYIPIP 97
V+ S ++W P E + +N P RE S P R P+ ++ G+
Sbjct: 1296 VEVPSMASSWGGPHFSPEHKE----LSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSS-- 1349
Query: 98 VLHEGAENRQVHPFHVYPQPGMQRFRTEAAAAAPQRSQSPLRGMPETTQPDKQCGQVAAA 157
+ E ++ P M+ T ++ S S L P+ + + +
Sbjct: 1350 EVKEDLNGPFLNQLETDPSLDMKEQSTRSSG----HSSSELS--PDAVEKAGMSSNQSIS 1403
Query: 158 AAAQPPASHGPERSQSPAASDCSSSSSSASLPSSGRSSLGSHQLPRGYISIPVIHEQNVT 217
+ P R +S +AS PS RS GS R P H + +
Sbjct: 1404 SPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSR-RSRSGSSPGLRDGSGTPSRHSLSGS 1462
Query: 218 RPAAQ-----PSFHQAQKTHYPAQQGEYQTHQPVYHKIQGDDWEPRPLRAASPFRSSVQG 272
P + PS +++ P + QT +P + + L +P R G
Sbjct: 1463 SPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCL---TPQRER-SG 1518
Query: 273 ASSREGSPARSSTPLHSPSPIRVHTVVDRPQQPMTHRETAPVSQPENKPESKPGPVGPEL 332
+ S + TPL S +D + S P++K +++ P+
Sbjct: 1519 SESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRT-PLRQRS 1577
Query: 333 PPGHIPIQVIRKEVDSKP-VSQKPPPPSEKVEVKVPPAPVPCP---------PPSPGPSA 382
G P EVDSK +S + EVK P P P +P P A
Sbjct: 1578 RSGSSP------EVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRA 1631
Query: 383 VPSSPKSVATEERAAPSTAPAEATPPKPGEAEAPPK 418
+P +S ++ + PS + +T P E PPK
Sbjct: 1632 LPRRSRSGSSSKGRGPSPEGSSSTESSP---EHPPK 1664
Score = 36.6 bits (83), Expect = 0.064
Identities = 43/214 (20%), Positives = 81/214 (37%), Gaps = 18/214 (8%)
Query: 56 SEGPKETPSSANGPSREGSRLPPAREGHPVYPQLRPGYIPIPVLHEGAENRQVHPFHVYP 115
S + S ++ EGS LP V P++ +P P R+ P P
Sbjct: 2548 SSSSSSSSSGSSSSDSEGSSLP-------VQPEVALKRVPSPTPAPKEAVREGRPPE--P 2598
Query: 116 QPGMQRFRTEAAAAAPQRSQSPLRGMPETTQPDKQCGQVAAAAAAQP-----PASHGPER 170
P ++ R+ +++++ S S ++ ++++++ PA GP+
Sbjct: 2599 TPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQA 2658
Query: 171 SQSPAASDCSSSSSSASLPSSGRSSLGSHQLPRGYISIPVIHEQNVTRPAAQPSFHQAQK 230
PA+ S S R + S + R PV E+ P P Q+
Sbjct: 2659 LPKPASPKKPPPGERRS--RSPRKPIDSLRDSRSLSYSPV--ERRRPSPQPSPRDQQSSS 2714
Query: 231 THYPAQQGEYQTHQPVYHKIQGDDWEPRPLRAAS 264
+ +++G+ + HK + + PRP+R S
Sbjct: 2715 SERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRS 2748
Score = 33.1 bits (74), Expect = 0.71
Identities = 64/292 (21%), Positives = 101/292 (34%), Gaps = 40/292 (13%)
Query: 52 PRVPSEGPKETPSSANGPSREGSRLPPAREGHPVYPQLRPGYIPIPVLHEGAENRQVHPF 111
PR PS G E SS + + P +R P P+L + G+E+ V
Sbjct: 1470 PRTPSRGRSECDSSPEPKALPQTPRPRSRS--PSSPELNNKCLTPQRERSGSES-SVDQK 1526
Query: 112 HVYPQPGMQRFRTEAA-------AAAPQR---SQSPLRGMPETTQPDKQCGQVAAAAAAQ 161
V P QR R+ ++ +A+PQ S S +T P +Q + ++
Sbjct: 1527 TVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVD 1586
Query: 162 PPASHGPERSQSPAASDCSSSSSSASLPSSGRSSLGSHQLPRGYISIPVIHEQNVTRPAA 221
+ P RS+S ++ + +A SG S + P P A
Sbjct: 1587 SKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPA---------------PRA 1631
Query: 222 QPSFHQA---QKTHYPAQQGEYQTHQPVYHKIQ------GDDWEPRPLRAASPFRSSVQG 272
P ++ K P+ +G T H + G P P + R+ +
Sbjct: 1632 LPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKS---RTPPRR 1688
Query: 273 ASSREGSPARSSTPLHSPSPIRVHTVVDRPQQPMTHRETAPVSQPENKPESK 324
SSR L S + R + P HR + VS PE +S+
Sbjct: 1689 RSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSR 1740
Score = 29.6 bits (65), Expect = 7.9
Identities = 29/125 (23%), Positives = 43/125 (34%), Gaps = 17/125 (13%)
Query: 343 RKEVDSKPVSQKPPPPSEKVEVKVPP-------APVPCPPPSPGPSAVPSSPKSVATEER 395
R E +SK + P P K + K P P + ++ S+ S + R
Sbjct: 219 RSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSR 278
Query: 396 AAPSTAPAEATP-----PKP-----GEAEAPPKHPGVLKVEAILEKVQGLEQAVDNFEGK 445
+ + A T P P GE +AP PG + +Q +E K
Sbjct: 279 SRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDK 338
Query: 446 KTDKK 450
DKK
Sbjct: 339 DKDKK 343
>gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]
Length = 825
Score = 65.1 bits (157), Expect = 2e-10
Identities = 72/306 (23%), Positives = 108/306 (35%), Gaps = 51/306 (16%)
Query: 127 AAAAPQRSQSPLRGMPETTQPDKQCGQVAAAAAAQPPASHGPERSQSPAASDCSSSSSSA 186
A AP QSPL P+ T ++ ++ AA +PPA P ++SP + + S+ + A
Sbjct: 450 AEEAPTEFQSPL---PKETTAEEASAEIQLLAATEPPADETPAEARSPLSEETSAEEAHA 506
Query: 187 SLPSSGRSSLGSHQLPRGYISIPVIHEQNVTRPAAQPSFHQAQKTHYPAQQGEYQTHQPV 246
+ S P+ E +A+ A + PA + + P+
Sbjct: 507 EVQS------------------PLAEETTAEEASAEIQLLAAIEA--PADETPAEAQSPL 546
Query: 247 YHKIQGDDWEPRPLRAASPFRSSVQGASSREGSPARSSTPLHSPSPIRVHTVVDRPQQPM 306
+ E P SP S +G S E PL P T + +
Sbjct: 547 SEETSA---EEAPAEVQSP---SAKGVSIEE-------APLELQPPSGEETTAEEASAAI 593
Query: 307 THRETAPVSQPENKPESKPGPVGPELPPGHI---PIQVIRKEVDSKPVSQKP----PPPS 359
S E E +P P E P + P + EV P + P PPP+
Sbjct: 594 QLLAATEASAEEAPAEVQPPPA--EEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPA 651
Query: 360 EKVEVKVPPAP---VPCPPPSPGPSAVPSSPKSVATEERAAPSTAPAEATPPK---PGEA 413
E+ +V P P P P P+ +S+ EE T A +PP P E
Sbjct: 652 EEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQSLPAEETPIEETLAAVHSPPADDVPAEE 711
Query: 414 EAPPKH 419
+ KH
Sbjct: 712 ASVDKH 717
Score = 63.9 bits (154), Expect = 4e-10
Identities = 110/499 (22%), Positives = 175/499 (35%), Gaps = 65/499 (13%)
Query: 63 PSSANGPSRE--GSRLPPAREGHPVYPQLRPGYIPIPVLHEGAENRQVHPFHVYPQPGMQ 120
PS+ PS E LPP E P L G I P + Q P V P P
Sbjct: 353 PSAEESPSEEPPAEILPPPAEKSPSVELL--GEIRSP-------SAQKAPIEVQPLPAEG 403
Query: 121 RFRTEAAAAAPQRSQSPLRG----MPETTQPDKQCGQVAAAAAAQPPASHGPERSQSPAA 176
A P + L +PE P ++ ++ + A + PA P QSP
Sbjct: 404 ALEEAPAKVEPPTVEETLADVQPLLPEEA-PREEARELQLSTAMETPAEEAPTEFQSPLP 462
Query: 177 SDCSSSSSSASLPSSGRSSLGSHQLPRGYISIPVIHEQNVTRPAAQPSFHQAQKTHYPAQ 236
+ ++ +SA + + + + P S P+ E + A+ A++T
Sbjct: 463 KETTAEEASAEIQLLAATEPPADETPAEARS-PLSEETSAEEAHAEVQSPLAEETTAEEA 521
Query: 237 QGEYQTHQPVYHKIQGDDWEPRPLRAASPFRSSVQGASSREGSPARSSTPLHSPSPIRVH 296
E Q + + D+ P A SP S E S + + SPS V
Sbjct: 522 SAEIQLLAAI--EAPADE---TPAEAQSPL--------SEETSAEEAPAEVQSPSAKGVS 568
Query: 297 TVVDRPQQPMTHRETAPVSQPENKPESKPGPVGPELPPGHIPIQVIRKEVDSKPVSQKPP 356
E AP+ E +P S E + + P +PP
Sbjct: 569 I------------EEAPL---ELQPPSGEETTAEEASAAIQLLAATEASAEEAPAEVQPP 613
Query: 357 PPSEKVEVKVPPAPVPCPPPSPGPSAVPSSPKSVATEERAAP--STAPAEATPP----KP 410
P E PA V PP P+ V P A E P APAE PP P
Sbjct: 614 PAEE------APAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAP 667
Query: 411 GEAEAPPKHPGVLKVEAILEKVQGLEQ---AVDNFEGKKTDKKYLMIEEYLTKELLALDS 467
E + PP +V+++ + +E+ AV + + ++++ L L
Sbjct: 668 AEVQPPPAEEAPAEVQSLPAEETPIEETLAAVHSPPADDVPAEEASVDKHSPPADLLLTE 727
Query: 468 VDP--EGRADVRQARRDGVRKVQTILEKL--EQKAIDVPGQVQVYELQPSNLEADQPLQA 523
P E A+V + + + ++E + E ++ V G + +L LE + +
Sbjct: 728 EFPIGEASAEVSPPPSEQTPEDEALVENVSTEFQSPQVAG-IPAVKLGSVVLEGEAKFEE 786
Query: 524 IMEMGAVAADKGKKNAGNA 542
+ ++ +V D N G A
Sbjct: 787 VSKINSVLKDLSNTNDGQA 805
Score = 37.0 bits (84), Expect = 0.049
Identities = 64/319 (20%), Positives = 112/319 (35%), Gaps = 35/319 (10%)
Query: 259 PLRAASPFRSSVQGASSREGSPAR--SSTPLHSPSPIRVHTVVDRPQQPMTHRETAPVS- 315
P+ R V +EGS + +S + PS + + Q P+ TA
Sbjct: 227 PVLLEDELREEVTVPVVQEGSAVKKVASAEIEPPSTEKFPAKI---QPPLVEEATAKAEP 283
Query: 316 QPENKPESKPGPVGPELPPGHIPIQVIRKEVDSKPVSQKPPPPSEKVEVKVPPAPVPCPP 375
+P + + P E P V V +P PP+E+ + PA + P
Sbjct: 284 RPAEETHVQVQPSTEETPDAEAATAVAENSVKVQP------PPAEEAPLVEFPAEIQPPS 337
Query: 376 PSPGPSAVPSSPKSVATEERAAPSTAPAEATPPKP---------GEAEAPPKHPGVLKVE 426
PS + + E + PAE PP GE +P ++V+
Sbjct: 338 AEESPSVELLAEILPPSAEESPSEEPPAEILPPPAEKSPSVELLGEIRSPSAQKAPIEVQ 397
Query: 427 AILEKVQGLEQAVDNFEGKKTDKKYLMIEEYLTKELLALDSVDPEGRADVRQARRDGVRK 486
L LE+A E ++ ++ L +E ++ + + + + +
Sbjct: 398 P-LPAEGALEEAPAKVEPPTVEETLADVQPLLPEEAPREEARELQLSTAMETPAEEAPTE 456
Query: 487 VQTILEKLEQKAIDVPGQVQVYELQPSNLEADQ-PLQAIMEMGAVAADKGKKNAGNAEDP 545
Q+ L K E A + ++Q+ L + AD+ P +A + +AE+
Sbjct: 457 FQSPLPK-ETTAEEASAEIQL--LAATEPPADETPAEARSPL---------SEETSAEEA 504
Query: 546 HTETQQPEATAAATSNPSS 564
H E Q P A S+
Sbjct: 505 HAEVQSPLAEETTAEEASA 523
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 63.2 bits (152), Expect = 6e-10
Identities = 90/350 (25%), Positives = 122/350 (34%), Gaps = 93/350 (26%)
Query: 140 GMPE---TTQPDKQCGQVAAAAAAQPPASHGPERSQSPAASDCSSSSSSASLPSSG-RSS 195
GMP+ T D G ++PP RS S S +PS G RS
Sbjct: 107 GMPKLRSTANRDNDSG------GSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSG 160
Query: 196 LGSHQLPRGYISIPVIHEQNVTRPAAQPSFHQAQKTHYPAQQGEYQTHQPVYHKIQGDDW 255
Q R P + + + P PS T P Q + P + G
Sbjct: 161 PPEPQRNRMPPPRPDVGSKPDSIPPPVPS------TPRPIQSSPHNRGSP---PVPGGPR 211
Query: 256 EPRPLRAASPF---RSSVQGASSREGSPARSSTPLHS-----PSPIRVHTVVDRP----- 302
+P P PF R + G S SP SS+P + P+P R + D+P
Sbjct: 212 QPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRA--LDDKPPPPPP 269
Query: 303 ---QQPMTHRETAPVSQPENK---------------------PESKPGPVGPELPPG--- 335
+P HRE P P+N P S+PGP P LPP
Sbjct: 270 PVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGP--PPLPPSSSG 327
Query: 336 -----HIPIQVIRKEVDSKPVSQK------PPPPSEKVEVKVPPAPV--------PCPPP 376
+P + + + P+ PPPPSE+ PP PV P PPP
Sbjct: 328 NDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSER-----PPPPVRDPPGRSGPLPPP 382
Query: 377 SP------GPSAVPSSPKSVATEERAAPSTAPAEATPPKPGEAEAPPKHP 420
P A+P++P+ + +P + P PP A APP P
Sbjct: 383 PPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPP 432
Score = 50.4 bits (119), Expect = 4e-06
Identities = 47/165 (28%), Positives = 60/165 (36%), Gaps = 34/165 (20%)
Query: 280 PARSSTPLHSPSPIRVHTVVDRPQQPMTHRETAPVSQPENKPESKPGPVGPELPPGHIPI 339
P S P P P+ RP Q H +P P + PGP P P G+
Sbjct: 174 PDVGSKPDSIPPPV---PSTPRPIQSSPHNRGSP-PVPGGPRQPSPGPTPPPFP-GNRGT 228
Query: 340 QVIRKEVDSKPVSQK---------PPPPSEKVEVKVPPAP-------------VPCPPPS 377
+ + P+S PP PS ++ K PP P VP PPP
Sbjct: 229 ALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQ 288
Query: 378 PGPSAVPSSPKSVATEERAAPSTAPAEATPP-KPGEAEAPPKHPG 421
VPS+P+ +A S AP PP +PG PP G
Sbjct: 289 NNKPPVPSTPRP------SASSQAPPPPPPPSRPGPPPLPPSSSG 327
Score = 50.1 bits (118), Expect = 6e-06
Identities = 92/430 (21%), Positives = 128/430 (29%), Gaps = 89/430 (20%)
Query: 17 GDRDPL-PPGWEIKIDPQTGWPFFVDHNSRTTTWNDPRVPSEGPKETPSSANGPSR-EGS 74
G R PL PPG ++ ++ P P P +P +GP + +
Sbjct: 123 GSRPPLLPPG---------------GRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRN 167
Query: 75 RLPPAREGHPVYPQL--RPGYIPIPVLHEGAENRQVHPFHVYPQPGMQRFRTEAAAAAPQ 132
R+PP R P + +P IP PV P+P + P
Sbjct: 168 RMPPPR------PDVGSKPDSIPPPVPST-------------PRPIQSSPHNRGSPPVPG 208
Query: 133 RSQSPLRGMPETTQPDKQCGQVAAAAAAQPPASHGPERSQSPAASDCSSSSSSASLPSSG 192
+ P G P + + + Q P S S P S + P
Sbjct: 209 GPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPP- 267
Query: 193 RSSLGSHQLPRGYISIPVIHEQNVTRPAAQPSFHQAQKTHYPAQQGEYQTHQPVYHKIQG 252
P + P IH + V P Q + T P+ + P +
Sbjct: 268 ---------PPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPG- 317
Query: 253 DDWEPRPLRAASPFRSSVQGASSREGSPARSSTPLHSPSPIRVHTVV----DRPQQPMTH 308
P PL +S R S + S+ PL PSP R + +RP P+
Sbjct: 318 ----PPPLPPSSSGNDETPRLPQRNLSLSSSTPPL--PSPGRSGPLPPPPSERPPPPVRD 371
Query: 309 RETAPVSQPENKPESKPGPVGPELPPGHIPIQVIRKEVDSKPVSQKPPPPSEKVEVKVPP 368
P P S+ G LP P R VDS +PP P ++ PP
Sbjct: 372 PPGRSGPLPPPPPVSRNGSTSRALPA--TPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPP 429
Query: 369 APVPC----------------------------PPPSPGPSAVPSSPKSVATEERAAPST 400
P P PPP P S P +A E + S
Sbjct: 430 PPPPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPEPYVQTTKSYPSKLARNESRSGSN 489
Query: 401 APAEATPPKP 410
PP P
Sbjct: 490 RRERGAPPLP 499
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 63.2 bits (152), Expect = 6e-10
Identities = 90/350 (25%), Positives = 122/350 (34%), Gaps = 93/350 (26%)
Query: 140 GMPE---TTQPDKQCGQVAAAAAAQPPASHGPERSQSPAASDCSSSSSSASLPSSG-RSS 195
GMP+ T D G ++PP RS S S +PS G RS
Sbjct: 107 GMPKLRSTANRDNDSG------GSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSG 160
Query: 196 LGSHQLPRGYISIPVIHEQNVTRPAAQPSFHQAQKTHYPAQQGEYQTHQPVYHKIQGDDW 255
Q R P + + + P PS T P Q + P + G
Sbjct: 161 PPEPQRNRMPPPRPDVGSKPDSIPPPVPS------TPRPIQSSPHNRGSP---PVPGGPR 211
Query: 256 EPRPLRAASPF---RSSVQGASSREGSPARSSTPLHS-----PSPIRVHTVVDRP----- 302
+P P PF R + G S SP SS+P + P+P R + D+P
Sbjct: 212 QPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRA--LDDKPPPPPP 269
Query: 303 ---QQPMTHRETAPVSQPENK---------------------PESKPGPVGPELPPG--- 335
+P HRE P P+N P S+PGP P LPP
Sbjct: 270 PVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGP--PPLPPSSSG 327
Query: 336 -----HIPIQVIRKEVDSKPVSQK------PPPPSEKVEVKVPPAPV--------PCPPP 376
+P + + + P+ PPPPSE+ PP PV P PPP
Sbjct: 328 NDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSER-----PPPPVRDPPGRSGPLPPP 382
Query: 377 SP------GPSAVPSSPKSVATEERAAPSTAPAEATPPKPGEAEAPPKHP 420
P A+P++P+ + +P + P PP A APP P
Sbjct: 383 PPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPP 432
Score = 50.4 bits (119), Expect = 4e-06
Identities = 47/165 (28%), Positives = 60/165 (36%), Gaps = 34/165 (20%)
Query: 280 PARSSTPLHSPSPIRVHTVVDRPQQPMTHRETAPVSQPENKPESKPGPVGPELPPGHIPI 339
P S P P P+ RP Q H +P P + PGP P P G+
Sbjct: 174 PDVGSKPDSIPPPV---PSTPRPIQSSPHNRGSP-PVPGGPRQPSPGPTPPPFP-GNRGT 228
Query: 340 QVIRKEVDSKPVSQK---------PPPPSEKVEVKVPPAP-------------VPCPPPS 377
+ + P+S PP PS ++ K PP P VP PPP
Sbjct: 229 ALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQ 288
Query: 378 PGPSAVPSSPKSVATEERAAPSTAPAEATPP-KPGEAEAPPKHPG 421
VPS+P+ +A S AP PP +PG PP G
Sbjct: 289 NNKPPVPSTPRP------SASSQAPPPPPPPSRPGPPPLPPSSSG 327
Score = 50.1 bits (118), Expect = 6e-06
Identities = 92/430 (21%), Positives = 128/430 (29%), Gaps = 89/430 (20%)
Query: 17 GDRDPL-PPGWEIKIDPQTGWPFFVDHNSRTTTWNDPRVPSEGPKETPSSANGPSR-EGS 74
G R PL PPG ++ ++ P P P +P +GP + +
Sbjct: 123 GSRPPLLPPG---------------GRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRN 167
Query: 75 RLPPAREGHPVYPQL--RPGYIPIPVLHEGAENRQVHPFHVYPQPGMQRFRTEAAAAAPQ 132
R+PP R P + +P IP PV P+P + P
Sbjct: 168 RMPPPR------PDVGSKPDSIPPPVPST-------------PRPIQSSPHNRGSPPVPG 208
Query: 133 RSQSPLRGMPETTQPDKQCGQVAAAAAAQPPASHGPERSQSPAASDCSSSSSSASLPSSG 192
+ P G P + + + Q P S S P S + P
Sbjct: 209 GPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPP- 267
Query: 193 RSSLGSHQLPRGYISIPVIHEQNVTRPAAQPSFHQAQKTHYPAQQGEYQTHQPVYHKIQG 252
P + P IH + V P Q + T P+ + P +
Sbjct: 268 ---------PPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPG- 317
Query: 253 DDWEPRPLRAASPFRSSVQGASSREGSPARSSTPLHSPSPIRVHTVV----DRPQQPMTH 308
P PL +S R S + S+ PL PSP R + +RP P+
Sbjct: 318 ----PPPLPPSSSGNDETPRLPQRNLSLSSSTPPL--PSPGRSGPLPPPPSERPPPPVRD 371
Query: 309 RETAPVSQPENKPESKPGPVGPELPPGHIPIQVIRKEVDSKPVSQKPPPPSEKVEVKVPP 368
P P S+ G LP P R VDS +PP P ++ PP
Sbjct: 372 PPGRSGPLPPPPPVSRNGSTSRALPA--TPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPP 429
Query: 369 APVPC----------------------------PPPSPGPSAVPSSPKSVATEERAAPST 400
P P PPP P S P +A E + S
Sbjct: 430 PPPPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPEPYVQTTKSYPSKLARNESRSGSN 489
Query: 401 APAEATPPKP 410
PP P
Sbjct: 490 RRERGAPPLP 499
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 62.8 bits (151), Expect = 8e-10
Identities = 101/407 (24%), Positives = 132/407 (32%), Gaps = 97/407 (23%)
Query: 55 PSEGPKETPSS--ANGPSREGSRLPPARE-----GHPVYPQL-RPGYIPIPVLHEGAENR 106
P +GP +TP + A P + + P ++ G V P L P PI G
Sbjct: 257 PIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPA 316
Query: 107 QVHPFHVYPQPGMQRFRTEAAAAAPQRSQSPLRGMPETTQPDKQCGQVAAAAAAQPPASH 166
Q P H QPG + A P PL P T +P Q +PPA
Sbjct: 317 Q-QPGHEKSQPGPAK-----PPAQPSGLTKPLAQQPGTVKPPVQ-----PPGTTKPPAQ- 364
Query: 167 GPERSQSPAASDCSSSSSSASLPSSGRSSLGSHQLPRGYISIPVIHEQNVTRPAAQPSFH 226
P P A S S+ P P+ P + + PA QP
Sbjct: 365 -PLGPAKPPAQQTGSEKPSSEQPG-----------PKALAQPPGVGKT----PAQQPG-- 406
Query: 227 QAQKTHYPAQQGEYQTHQPVYHKIQGDDWEPRPLRAASPFRSSVQGASSREGSPARSSTP 286
PA+ Q P +PL A P G S +P + TP
Sbjct: 407 -------PAKPPTQQVGTP------------KPL-AQQP------GLQSPAKAPGPTKTP 440
Query: 287 LHSPSPIRVHTVVDRPQQPMTHRETAPVSQPENKPESKPGPV-------GPELPPGHIPI 339
+ P P ++ QQ + +A + P P PGP GP PP P
Sbjct: 441 VQQPGPGKIPA-----QQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQP- 494
Query: 340 QVIRKEVDSKPVSQKP----PPPSEKVEVKVPPAPVPCPPPSPGPSAVPSSPKSVATEER 395
+KP SQ+P PPP + P P P PG + PS A
Sbjct: 495 ------GSAKPPSQQPGSTKPPPQQ-------PGPAKPSPQQPGSTKPPSQQPGSAKPSA 541
Query: 396 AAPSTAPAEA---TPPKPGEAEAPPKHPGVLKVEAILEKVQGLEQAV 439
PS A A T P P P + A QGL + +
Sbjct: 542 QQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTI 588
Score = 60.5 bits (145), Expect = 4e-09
Identities = 80/326 (24%), Positives = 110/326 (33%), Gaps = 52/326 (15%)
Query: 125 EAAAAAPQRSQSPLRGMPETTQPDKQCGQVAAAAAAQPPASHGPERSQSPAASDCSSSSS 184
E + P + P++G +T Q D A+ P R Q+ A S
Sbjct: 245 EKIKSQPPGTGKPIQGPTQTPQTDH----------AKLPLQRDASRPQTKQADIVRGESV 294
Query: 185 SASLPSSGRSSLGSHQLPRGYISIPVIHEQNVTRPA---AQPS-----FHQAQKTHYPAQ 236
SLPS + + + P HE++ PA AQPS Q T P
Sbjct: 295 KPSLPSPSKPPIQQPTPGKPPAQQPG-HEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPV 353
Query: 237 QGEYQTHQPVYHKIQGDDWEPRPLRAASPFRSSVQGASSREGSPARSSTPLHSPSPIRVH 296
Q T P + G P + S G + P TP P P +
Sbjct: 354 QPPGTTKPPA--QPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPP 411
Query: 297 TVVDRPQQPMTHR----ETAPVSQPENKPESKPGPVGPELPPGHIPIQVI-------RKE 345
T +P+ + A P P +PGP G IP Q ++
Sbjct: 412 TQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGP-------GKIPAQQAGPGKTSAQQT 464
Query: 346 VDSKPVSQKP----PPPSEKVEVKVPPAPVPCPPPSPGPSAVPSSPKSVATEERAAPSTA 401
+KP SQ P PPP + P P PP PG + PS P
Sbjct: 465 GPTKPPSQLPGPAKPPPQQ-------PGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPG-- 515
Query: 402 PAEATPPKPGEAEAPPKHPGVLKVEA 427
PA+ +P +PG + P + PG K A
Sbjct: 516 PAKPSPQQPGSTKPPSQQPGSAKPSA 541
Score = 50.4 bits (119), Expect = 4e-06
Identities = 86/400 (21%), Positives = 135/400 (33%), Gaps = 68/400 (17%)
Query: 53 RVPSE--GPKETPSSANGPSREGSRLP------PAREGHPVYPQLRPGYIPIPVLHEGAE 104
++P++ GP +T + GP++ S+LP P + G P +PG P G+
Sbjct: 448 KIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGST 507
Query: 105 N---RQVHPFHVYPQ-PGMQRFRTEAAAAAPQRSQSPLRGMPETTQPDKQCGQVAAAAAA 160
+Q P PQ PG + ++ +A +Q P P Q K Q +
Sbjct: 508 KPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPL 567
Query: 161 QPPASHGPERSQSPAASDCSSSSSSASLPSSGRSSLGSHQLPRGYISIPVIHEQNVTRPA 220
QPP P Q P S P + L H + + + V
Sbjct: 568 QPPTV-SPSAKQPP-----SQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLC 621
Query: 221 A-QPSFHQAQKTHYPAQQGEYQTHQPVYHKIQGDDWEPRPLRAASPFRSSVQGASSREGS 279
P+ H + + + + + G D P P +++
Sbjct: 622 GFNPNPHLTEVKEWLCLNCQMK-------RALGGDLAPVPSSPQPKLKTA---------- 664
Query: 280 PARSSTPLHSPSPIRVHTVVDRPQQPMTHRETAPVSQPENKPESKPGPVGPELPPGHIPI 339
P +++ + SP +PQQ ++ AP PE K P + P H
Sbjct: 665 PVTTTSAVSKSSP--------QPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSP 716
Query: 340 QVIRKEVDSKPVSQKPPPPSE-KVEVKVPPAPV----PCPPPSPGPSA------------ 382
K+ KP PP E V + APV P P P+
Sbjct: 717 SAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKP 776
Query: 383 -VPSSPKSVATEERAAP-----STAPAEATPPKPGEAEAP 416
+PSS EE+ P S P+++ PP GE +P
Sbjct: 777 DIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPP-TGEKVSP 815
Score = 44.3 bits (103), Expect = 3e-04
Identities = 76/379 (20%), Positives = 130/379 (34%), Gaps = 52/379 (13%)
Query: 115 PQPGMQRFRTEAAAAAPQRSQSPLRGMPETTQPDKQCGQVAAAAAAQPPASHGPERSQSP 174
PQP ++ +A + S P + P+ KQ A PP P SP
Sbjct: 657 PQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSP 716
Query: 175 AA-SDCSSSSSSASLPSSGRSSLGSHQLPRGYISIPVIHEQNVTRPAAQ--PSFHQAQKT 231
+A + + S S P+ + + + ++ + + +P S K
Sbjct: 717 SAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKP 776
Query: 232 HYPAQQGEYQTHQPVYHKIQGDDWEPRPLRAASPFRSSVQGASSRE-GSPARSSTPLHSP 290
P+ + + Q + ++ D +P ++ P V S+ PA S + P
Sbjct: 777 DIPSSKVQSQAEEKTTPPLKTD--SAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHP 834
Query: 291 SPIRVHTVVDRPQQPMTHRETAPVSQPE--NKPESKPGPVGPELPPGHIPIQVIRKEVDS 348
P + + P+ +E +Q + KP++KP P G PPG P + V +
Sbjct: 835 GP-SSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPG--PRPTAGQTVPT 891
Query: 349 KPVSQKPPPPSEKVEVKV-----PPAPVPCPP---------------------------- 375
S KP S + + + P P P
Sbjct: 892 PQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQ 951
Query: 376 PSPGPSAVPSSPKSVATEERAAPSTAPAEATPPK-PGEAEAPPKHPGVLKVEA---ILEK 431
P P + P +P ++ APS P PPK G+A P +K E EK
Sbjct: 952 PGPHSQSGPGAP----MKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEK 1007
Query: 432 VQGLEQAVDNFEGKKTDKK 450
++ + + +T+KK
Sbjct: 1008 LEPKAEQAPTVKRTETEKK 1026
Score = 43.5 bits (101), Expect = 5e-04
Identities = 81/375 (21%), Positives = 133/375 (35%), Gaps = 45/375 (12%)
Query: 58 GPKETPSSANGPSREGSRLP----PAREGHPVYPQLR---PGYIPIPVLHEGAENRQ--- 107
GP + P+ G + ++ P PA+ P ++ PG IP G + Q
Sbjct: 406 GPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTG 465
Query: 108 -VHPFHVYPQPGMQRFRTEAAAAAPQR---SQSPLRGMPETTQPDKQCGQVAAAAAAQPP 163
P P P + A P + S P P +T+P Q A + QP
Sbjct: 466 PTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPG 525
Query: 164 ASHGPERSQSPAASDCSSSSSSASLPSSGRSSLGSHQLPRGYISIPVIHEQNVTRPAAQP 223
++ P SQ P ++ S+ S + PS+ +S+ Q G + V+ A QP
Sbjct: 526 STKPP--SQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSG----KPLQPPTVSPSAKQP 579
Query: 224 SFHQAQKTHYP-AQQGEYQTHQPVYHKIQGDDWEPRPLRAASPFRSSVQGASSREGSPAR 282
KT P E H P E + +++V +P
Sbjct: 580 PSQGLPKTICPLCNTTELLLHVP----------EKANFNTCTECQTTVCSLCGFNPNPHL 629
Query: 283 SSTPLHSPSPIRVHTVVDR-----PQQPMTHRETAPVSQPENKPESKPGPVGPELPPGHI 337
+ ++ + P P +TAPV+ +S P P
Sbjct: 630 TEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAA 689
Query: 338 PIQVIRKEVDSKPVSQKPPPPSEKVEVKVPPAPVPCPPPSPGPSAVPSSPK--SVATEER 395
P ++++ P +KPPP ++ + P+ PP + P+ PK SV +E+
Sbjct: 690 P----KQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQD 745
Query: 396 AAPSTAPAEATPPKP 410
AP A+ P +P
Sbjct: 746 KAP---VADDKPKQP 757
Score = 42.4 bits (98), Expect = 0.001
Identities = 81/400 (20%), Positives = 125/400 (31%), Gaps = 66/400 (16%)
Query: 47 TTWNDPRVPSEGPKET-PSSANGPSREGSRLPPAREGHPVYPQLRPGYIPIPVLHEGAEN 105
TT + S P++T P P ++ S+ P ++ P+ Q P LH
Sbjct: 667 TTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQ--------PTLHGSPSA 718
Query: 106 RQVHPFHVY-------PQPGMQRFRTEAAAAAPQRSQSPLRGMPETTQPDKQCGQVAAAA 158
+ P P+ + A A + + P P T
Sbjct: 719 KAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDI 778
Query: 159 AAQPPASHGPERSQSPAASDCSSSSSSASLPSSGR--SSLGSHQLPRGYISIPVI-HEQN 215
+ S E++ P +D S+ S S P +G S S +PR +I H
Sbjct: 779 PSSKVQSQAEEKTTPPLKTD--SAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGP 836
Query: 216 VTRPAAQPSFHQAQKTHYPAQQGEYQTHQPVYHKIQGDDWEPRPLRAASPFRSSVQGASS 275
+ Q QK P + + +P D +P P + +P
Sbjct: 837 SSESKGQKQVDPVQKKEEPKKAQTKMSPKP--------DAKPMPKGSPTP-------PGP 881
Query: 276 REGSPARSSTPLHSPSP--------IRVHTVVDRPQ-QPMTHRET---------APVSQP 317
R + TP SP P + + ++ D P+ QP T +ET A +
Sbjct: 882 RPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQ 941
Query: 318 ENKPESKPGPVGPELPPGHIPIQVIRKEVDSKPVSQKPPPPSEKVEVKVPPAPVPCPPPS 377
+ S G GP G P+ Q P P S+ + PP PP+
Sbjct: 942 ASNLISTAGQPGPHSQSG-----------PGAPMKQAPAP-SQPPTSQGPPKSTGQAPPA 989
Query: 378 PGPSAVPSSPKSVATEERAAPSTAPAEATPPKPGEAEAPP 417
P S E+ P A E + PP
Sbjct: 990 PAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPP 1029
Score = 41.6 bits (96), Expect = 0.002
Identities = 21/61 (34%), Positives = 27/61 (44%), Gaps = 4/61 (6%)
Query: 348 SKPVSQKPPPPSEKVEVKVPPAPVPCPPPSPGPSAVPSSPKSVATEERAAPSTAPAEATP 407
S +S +PPPP PP P P PPP P P P+SPK ++ +P
Sbjct: 2398 SLDISAQPPPPPPPP----PPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTAT 2453
Query: 408 P 408
P
Sbjct: 2454 P 2454
Score = 40.4 bits (93), Expect = 0.004
Identities = 44/159 (27%), Positives = 56/159 (35%), Gaps = 22/159 (13%)
Query: 278 GSPARSSTPLHSPSPIRVHTVVDRPQQPMTHRETAPVSQPENKPESKPGPVGPELPPGHI 337
GSP+ SS P P P + +D QP P P P P P P LPP
Sbjct: 2379 GSPSVSSLPA-KPRPFFRSSSLDISAQP-----PPPPPPPPPPPPPPPPPPPPPLPPPTS 2432
Query: 338 PIQVI---RKEVDSKPVSQKPPPPSEKVEVKVP--------PAPVPC----PPPSPGPSA 382
P I +K + PV+ P ++ P C PP P PS+
Sbjct: 2433 PKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSS 2492
Query: 383 VPSSPKSVATEERAAPSTAPAEATPPKPGEAEAPPK-HP 420
+PS E + P AP P P + P HP
Sbjct: 2493 IPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHP 2531
Score = 38.1 bits (87), Expect = 0.022
Identities = 26/89 (29%), Positives = 33/89 (37%), Gaps = 8/89 (8%)
Query: 329 GPELPPGHIPIQVIRKEVDSKPVSQKPPPPSEKVEVKVPPAPVPCPPPSPGPSAVPSSPK 388
G E P +P V S P +P S +++ P P P PPP P P P P
Sbjct: 2368 GQEKPASQLPSG--SPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPP 2425
Query: 389 SVATEERAAPSTAPAEATPPKPGEAEAPP 417
+ P T+P PK A P
Sbjct: 2426 PL------PPPTSPKPTILPKKKLTVASP 2448
Score = 34.3 bits (77), Expect = 0.32
Identities = 75/327 (22%), Positives = 124/327 (37%), Gaps = 69/327 (21%)
Query: 140 GMPETTQPDKQCGQVAAAAAAQPPASHG-PERSQSPAASDCSSSSSSASLPSSGRSSLGS 198
G+PE G AAAAA + G P + PA + S S + +
Sbjct: 11 GLPE--------GLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQIAAVMSR 62
Query: 199 HQ-LPRGYISIPVIHEQNVTRPAA--QPSFHQAQK---THYPAQQGEY----QTHQPVYH 248
Q LP+G S+P PAA PS H+ Q+ +H P Q G + QP
Sbjct: 63 AQGLPKG--SVP---------PAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLS 111
Query: 249 KIQGDDW--EPRPLRAASPFRSSVQGASSRE------------------GSPARSSTPLH 288
K + D + L SP S++ + SR + + S+ ++
Sbjct: 112 KSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVN 171
Query: 289 SPSPIRVHTVVDRPQQPMTHRETAPVSQPENKPESKPGPVGPELPPGHIPIQ------VI 342
+P + + + Q+ T ++ V + + KPE P + PP IP Q +
Sbjct: 172 KFNPFDLISDSEASQEETTKKQKV-VQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPL 230
Query: 343 RKEVDSKPVSQKPPPPSEKVEVKVP----PAPVPCPPPSPGPSAVP-----SSPKSVATE 393
+++ K +S + P EK++ + P P P P + +P S P++ +
Sbjct: 231 QQDGTPKSISSQQP---EKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQAD 287
Query: 394 ERAAPSTAPAEATPPKPGEAEAPPKHP 420
S P+ +P KP + P P
Sbjct: 288 IVRGESVKPSLPSPSKPPIQQPTPGKP 314
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 62.8 bits (151), Expect = 8e-10
Identities = 101/407 (24%), Positives = 132/407 (32%), Gaps = 97/407 (23%)
Query: 55 PSEGPKETPSS--ANGPSREGSRLPPARE-----GHPVYPQL-RPGYIPIPVLHEGAENR 106
P +GP +TP + A P + + P ++ G V P L P PI G
Sbjct: 257 PIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPA 316
Query: 107 QVHPFHVYPQPGMQRFRTEAAAAAPQRSQSPLRGMPETTQPDKQCGQVAAAAAAQPPASH 166
Q P H QPG + A P PL P T +P Q +PPA
Sbjct: 317 Q-QPGHEKSQPGPAK-----PPAQPSGLTKPLAQQPGTVKPPVQ-----PPGTTKPPAQ- 364
Query: 167 GPERSQSPAASDCSSSSSSASLPSSGRSSLGSHQLPRGYISIPVIHEQNVTRPAAQPSFH 226
P P A S S+ P P+ P + + PA QP
Sbjct: 365 -PLGPAKPPAQQTGSEKPSSEQPG-----------PKALAQPPGVGKT----PAQQPG-- 406
Query: 227 QAQKTHYPAQQGEYQTHQPVYHKIQGDDWEPRPLRAASPFRSSVQGASSREGSPARSSTP 286
PA+ Q P +PL A P G S +P + TP
Sbjct: 407 -------PAKPPTQQVGTP------------KPL-AQQP------GLQSPAKAPGPTKTP 440
Query: 287 LHSPSPIRVHTVVDRPQQPMTHRETAPVSQPENKPESKPGPV-------GPELPPGHIPI 339
+ P P ++ QQ + +A + P P PGP GP PP P
Sbjct: 441 VQQPGPGKIPA-----QQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQP- 494
Query: 340 QVIRKEVDSKPVSQKP----PPPSEKVEVKVPPAPVPCPPPSPGPSAVPSSPKSVATEER 395
+KP SQ+P PPP + P P P PG + PS A
Sbjct: 495 ------GSAKPPSQQPGSTKPPPQQ-------PGPAKPSPQQPGSTKPPSQQPGSAKPSA 541
Query: 396 AAPSTAPAEA---TPPKPGEAEAPPKHPGVLKVEAILEKVQGLEQAV 439
PS A A T P P P + A QGL + +
Sbjct: 542 QQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTI 588
Score = 60.5 bits (145), Expect = 4e-09
Identities = 80/326 (24%), Positives = 110/326 (33%), Gaps = 52/326 (15%)
Query: 125 EAAAAAPQRSQSPLRGMPETTQPDKQCGQVAAAAAAQPPASHGPERSQSPAASDCSSSSS 184
E + P + P++G +T Q D A+ P R Q+ A S
Sbjct: 245 EKIKSQPPGTGKPIQGPTQTPQTDH----------AKLPLQRDASRPQTKQADIVRGESV 294
Query: 185 SASLPSSGRSSLGSHQLPRGYISIPVIHEQNVTRPA---AQPS-----FHQAQKTHYPAQ 236
SLPS + + + P HE++ PA AQPS Q T P
Sbjct: 295 KPSLPSPSKPPIQQPTPGKPPAQQPG-HEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPV 353
Query: 237 QGEYQTHQPVYHKIQGDDWEPRPLRAASPFRSSVQGASSREGSPARSSTPLHSPSPIRVH 296
Q T P + G P + S G + P TP P P +
Sbjct: 354 QPPGTTKPPA--QPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPP 411
Query: 297 TVVDRPQQPMTHR----ETAPVSQPENKPESKPGPVGPELPPGHIPIQVI-------RKE 345
T +P+ + A P P +PGP G IP Q ++
Sbjct: 412 TQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGP-------GKIPAQQAGPGKTSAQQT 464
Query: 346 VDSKPVSQKP----PPPSEKVEVKVPPAPVPCPPPSPGPSAVPSSPKSVATEERAAPSTA 401
+KP SQ P PPP + P P PP PG + PS P
Sbjct: 465 GPTKPPSQLPGPAKPPPQQ-------PGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPG-- 515
Query: 402 PAEATPPKPGEAEAPPKHPGVLKVEA 427
PA+ +P +PG + P + PG K A
Sbjct: 516 PAKPSPQQPGSTKPPSQQPGSAKPSA 541
Score = 50.4 bits (119), Expect = 4e-06
Identities = 86/400 (21%), Positives = 135/400 (33%), Gaps = 68/400 (17%)
Query: 53 RVPSE--GPKETPSSANGPSREGSRLP------PAREGHPVYPQLRPGYIPIPVLHEGAE 104
++P++ GP +T + GP++ S+LP P + G P +PG P G+
Sbjct: 448 KIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGST 507
Query: 105 N---RQVHPFHVYPQ-PGMQRFRTEAAAAAPQRSQSPLRGMPETTQPDKQCGQVAAAAAA 160
+Q P PQ PG + ++ +A +Q P P Q K Q +
Sbjct: 508 KPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPL 567
Query: 161 QPPASHGPERSQSPAASDCSSSSSSASLPSSGRSSLGSHQLPRGYISIPVIHEQNVTRPA 220
QPP P Q P S P + L H + + + V
Sbjct: 568 QPPTV-SPSAKQPP-----SQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLC 621
Query: 221 A-QPSFHQAQKTHYPAQQGEYQTHQPVYHKIQGDDWEPRPLRAASPFRSSVQGASSREGS 279
P+ H + + + + + G D P P +++
Sbjct: 622 GFNPNPHLTEVKEWLCLNCQMK-------RALGGDLAPVPSSPQPKLKTA---------- 664
Query: 280 PARSSTPLHSPSPIRVHTVVDRPQQPMTHRETAPVSQPENKPESKPGPVGPELPPGHIPI 339
P +++ + SP +PQQ ++ AP PE K P + P H
Sbjct: 665 PVTTTSAVSKSSP--------QPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSP 716
Query: 340 QVIRKEVDSKPVSQKPPPPSE-KVEVKVPPAPV----PCPPPSPGPSA------------ 382
K+ KP PP E V + APV P P P+
Sbjct: 717 SAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKP 776
Query: 383 -VPSSPKSVATEERAAP-----STAPAEATPPKPGEAEAP 416
+PSS EE+ P S P+++ PP GE +P
Sbjct: 777 DIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPP-TGEKVSP 815
Score = 44.3 bits (103), Expect = 3e-04
Identities = 76/379 (20%), Positives = 130/379 (34%), Gaps = 52/379 (13%)
Query: 115 PQPGMQRFRTEAAAAAPQRSQSPLRGMPETTQPDKQCGQVAAAAAAQPPASHGPERSQSP 174
PQP ++ +A + S P + P+ KQ A PP P SP
Sbjct: 657 PQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSP 716
Query: 175 AA-SDCSSSSSSASLPSSGRSSLGSHQLPRGYISIPVIHEQNVTRPAAQ--PSFHQAQKT 231
+A + + S S P+ + + + ++ + + +P S K
Sbjct: 717 SAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKP 776
Query: 232 HYPAQQGEYQTHQPVYHKIQGDDWEPRPLRAASPFRSSVQGASSRE-GSPARSSTPLHSP 290
P+ + + Q + ++ D +P ++ P V S+ PA S + P
Sbjct: 777 DIPSSKVQSQAEEKTTPPLKTD--SAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHP 834
Query: 291 SPIRVHTVVDRPQQPMTHRETAPVSQPE--NKPESKPGPVGPELPPGHIPIQVIRKEVDS 348
P + + P+ +E +Q + KP++KP P G PPG P + V +
Sbjct: 835 GP-SSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPG--PRPTAGQTVPT 891
Query: 349 KPVSQKPPPPSEKVEVKV-----PPAPVPCPP---------------------------- 375
S KP S + + + P P P
Sbjct: 892 PQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQ 951
Query: 376 PSPGPSAVPSSPKSVATEERAAPSTAPAEATPPK-PGEAEAPPKHPGVLKVEA---ILEK 431
P P + P +P ++ APS P PPK G+A P +K E EK
Sbjct: 952 PGPHSQSGPGAP----MKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEK 1007
Query: 432 VQGLEQAVDNFEGKKTDKK 450
++ + + +T+KK
Sbjct: 1008 LEPKAEQAPTVKRTETEKK 1026
Score = 43.5 bits (101), Expect = 5e-04
Identities = 81/375 (21%), Positives = 133/375 (35%), Gaps = 45/375 (12%)
Query: 58 GPKETPSSANGPSREGSRLP----PAREGHPVYPQLR---PGYIPIPVLHEGAENRQ--- 107
GP + P+ G + ++ P PA+ P ++ PG IP G + Q
Sbjct: 406 GPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTG 465
Query: 108 -VHPFHVYPQPGMQRFRTEAAAAAPQR---SQSPLRGMPETTQPDKQCGQVAAAAAAQPP 163
P P P + A P + S P P +T+P Q A + QP
Sbjct: 466 PTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPG 525
Query: 164 ASHGPERSQSPAASDCSSSSSSASLPSSGRSSLGSHQLPRGYISIPVIHEQNVTRPAAQP 223
++ P SQ P ++ S+ S + PS+ +S+ Q G + V+ A QP
Sbjct: 526 STKPP--SQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSG----KPLQPPTVSPSAKQP 579
Query: 224 SFHQAQKTHYP-AQQGEYQTHQPVYHKIQGDDWEPRPLRAASPFRSSVQGASSREGSPAR 282
KT P E H P E + +++V +P
Sbjct: 580 PSQGLPKTICPLCNTTELLLHVP----------EKANFNTCTECQTTVCSLCGFNPNPHL 629
Query: 283 SSTPLHSPSPIRVHTVVDR-----PQQPMTHRETAPVSQPENKPESKPGPVGPELPPGHI 337
+ ++ + P P +TAPV+ +S P P
Sbjct: 630 TEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAA 689
Query: 338 PIQVIRKEVDSKPVSQKPPPPSEKVEVKVPPAPVPCPPPSPGPSAVPSSPK--SVATEER 395
P ++++ P +KPPP ++ + P+ PP + P+ PK SV +E+
Sbjct: 690 P----KQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQD 745
Query: 396 AAPSTAPAEATPPKP 410
AP A+ P +P
Sbjct: 746 KAP---VADDKPKQP 757
Score = 42.4 bits (98), Expect = 0.001
Identities = 81/400 (20%), Positives = 125/400 (31%), Gaps = 66/400 (16%)
Query: 47 TTWNDPRVPSEGPKET-PSSANGPSREGSRLPPAREGHPVYPQLRPGYIPIPVLHEGAEN 105
TT + S P++T P P ++ S+ P ++ P+ Q P LH
Sbjct: 667 TTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQ--------PTLHGSPSA 718
Query: 106 RQVHPFHVY-------PQPGMQRFRTEAAAAAPQRSQSPLRGMPETTQPDKQCGQVAAAA 158
+ P P+ + A A + + P P T
Sbjct: 719 KAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDI 778
Query: 159 AAQPPASHGPERSQSPAASDCSSSSSSASLPSSGR--SSLGSHQLPRGYISIPVI-HEQN 215
+ S E++ P +D S+ S S P +G S S +PR +I H
Sbjct: 779 PSSKVQSQAEEKTTPPLKTD--SAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGP 836
Query: 216 VTRPAAQPSFHQAQKTHYPAQQGEYQTHQPVYHKIQGDDWEPRPLRAASPFRSSVQGASS 275
+ Q QK P + + +P D +P P + +P
Sbjct: 837 SSESKGQKQVDPVQKKEEPKKAQTKMSPKP--------DAKPMPKGSPTP-------PGP 881
Query: 276 REGSPARSSTPLHSPSP--------IRVHTVVDRPQ-QPMTHRET---------APVSQP 317
R + TP SP P + + ++ D P+ QP T +ET A +
Sbjct: 882 RPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQ 941
Query: 318 ENKPESKPGPVGPELPPGHIPIQVIRKEVDSKPVSQKPPPPSEKVEVKVPPAPVPCPPPS 377
+ S G GP G P+ Q P P S+ + PP PP+
Sbjct: 942 ASNLISTAGQPGPHSQSG-----------PGAPMKQAPAP-SQPPTSQGPPKSTGQAPPA 989
Query: 378 PGPSAVPSSPKSVATEERAAPSTAPAEATPPKPGEAEAPP 417
P S E+ P A E + PP
Sbjct: 990 PAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPP 1029
Score = 41.6 bits (96), Expect = 0.002
Identities = 21/61 (34%), Positives = 27/61 (44%), Gaps = 4/61 (6%)
Query: 348 SKPVSQKPPPPSEKVEVKVPPAPVPCPPPSPGPSAVPSSPKSVATEERAAPSTAPAEATP 407
S +S +PPPP PP P P PPP P P P+SPK ++ +P
Sbjct: 2398 SLDISAQPPPPPPPP----PPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTAT 2453
Query: 408 P 408
P
Sbjct: 2454 P 2454
Score = 40.4 bits (93), Expect = 0.004
Identities = 44/159 (27%), Positives = 56/159 (35%), Gaps = 22/159 (13%)
Query: 278 GSPARSSTPLHSPSPIRVHTVVDRPQQPMTHRETAPVSQPENKPESKPGPVGPELPPGHI 337
GSP+ SS P P P + +D QP P P P P P P LPP
Sbjct: 2379 GSPSVSSLPA-KPRPFFRSSSLDISAQP-----PPPPPPPPPPPPPPPPPPPPPLPPPTS 2432
Query: 338 PIQVI---RKEVDSKPVSQKPPPPSEKVEVKVP--------PAPVPC----PPPSPGPSA 382
P I +K + PV+ P ++ P C PP P PS+
Sbjct: 2433 PKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSS 2492
Query: 383 VPSSPKSVATEERAAPSTAPAEATPPKPGEAEAPPK-HP 420
+PS E + P AP P P + P HP
Sbjct: 2493 IPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHP 2531
Score = 38.1 bits (87), Expect = 0.022
Identities = 26/89 (29%), Positives = 33/89 (37%), Gaps = 8/89 (8%)
Query: 329 GPELPPGHIPIQVIRKEVDSKPVSQKPPPPSEKVEVKVPPAPVPCPPPSPGPSAVPSSPK 388
G E P +P V S P +P S +++ P P P PPP P P P P
Sbjct: 2368 GQEKPASQLPSG--SPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPP 2425
Query: 389 SVATEERAAPSTAPAEATPPKPGEAEAPP 417
+ P T+P PK A P
Sbjct: 2426 PL------PPPTSPKPTILPKKKLTVASP 2448
Score = 34.3 bits (77), Expect = 0.32
Identities = 75/327 (22%), Positives = 124/327 (37%), Gaps = 69/327 (21%)
Query: 140 GMPETTQPDKQCGQVAAAAAAQPPASHG-PERSQSPAASDCSSSSSSASLPSSGRSSLGS 198
G+PE G AAAAA + G P + PA + S S + +
Sbjct: 11 GLPE--------GLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQIAAVMSR 62
Query: 199 HQ-LPRGYISIPVIHEQNVTRPAA--QPSFHQAQK---THYPAQQGEY----QTHQPVYH 248
Q LP+G S+P PAA PS H+ Q+ +H P Q G + QP
Sbjct: 63 AQGLPKG--SVP---------PAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLS 111
Query: 249 KIQGDDW--EPRPLRAASPFRSSVQGASSRE------------------GSPARSSTPLH 288
K + D + L SP S++ + SR + + S+ ++
Sbjct: 112 KSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVN 171
Query: 289 SPSPIRVHTVVDRPQQPMTHRETAPVSQPENKPESKPGPVGPELPPGHIPIQ------VI 342
+P + + + Q+ T ++ V + + KPE P + PP IP Q +
Sbjct: 172 KFNPFDLISDSEASQEETTKKQKV-VQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPL 230
Query: 343 RKEVDSKPVSQKPPPPSEKVEVKVP----PAPVPCPPPSPGPSAVP-----SSPKSVATE 393
+++ K +S + P EK++ + P P P P + +P S P++ +
Sbjct: 231 QQDGTPKSISSQQP---EKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQAD 287
Query: 394 ERAAPSTAPAEATPPKPGEAEAPPKHP 420
S P+ +P KP + P P
Sbjct: 288 IVRGESVKPSLPSPSKPPIQQPTPGKP 314
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 62.4 bits (150), Expect = 1e-09
Identities = 78/339 (23%), Positives = 120/339 (35%), Gaps = 56/339 (16%)
Query: 100 HEGAENRQVHPFHVYPQPGMQRFRTEAAAAAPQRSQSPLRGMPETTQPDKQCGQVAAAAA 159
H G E ++ H H + +A A PQ+ P + P P +Q
Sbjct: 730 HPGREQKKHHHHH-------HQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQ--------- 773
Query: 160 AQPPASHGPERSQSPAASDCSSSSS---SASLPSSGRSSLGSHQLPRGYISIPVIHEQNV 216
QPP P AA SS + +P GS P G+ + P++H +
Sbjct: 774 QQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILH---L 830
Query: 217 TRPAAQPSFHQAQKTHYPAQQGEYQTHQP--VYHKIQGDDWEPRPLRAASPFRSSVQGAS 274
+P P Q + P ++ P +++ + P AA P + + A
Sbjct: 831 PQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAV 890
Query: 275 SREGSPARSSTPLHSPSPIRVHTVV-----DRPQQPMTHRETAPVSQPENKPESKPGPVG 329
S PA + TPL P+ V + P P+T + Q K + P P+
Sbjct: 891 S----PALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQP-PTPLL 945
Query: 330 PELPPGHIPIQVIRKEVDSKPVSQKPPPPSEKVEVKVPPAPVPCPPP----------SPG 379
P + +V S+P PPPP V+ ++ P P PPP P
Sbjct: 946 PSV------------KVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPP 993
Query: 380 PSAVPSSPKSVATEERAAPSTAPAEATPPKPGEAEAPPK 418
P V P +T + P + P PG+ PP+
Sbjct: 994 PRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQ 1032
Score = 42.0 bits (97), Expect = 0.002
Identities = 34/110 (30%), Positives = 47/110 (42%), Gaps = 9/110 (8%)
Query: 315 SQPENKPESKP-GPVGPELPPGHIPIQVIRKEVDSKPVSQKPPPPSEKVEVKVPPAPVPC 373
S+ E P+SK G G E H ++ + PV Q+PPPP ++ PP
Sbjct: 717 SETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPA-PVPQQPPPPPQQPPPPPPPQQQQQ 775
Query: 374 PPPSPGPSAVPSSPKSVATEERAAP----STAPAEATPPKPGEAEAPPKH 419
PPP P P PS P+ A +++P +T P PG P H
Sbjct: 776 PPPPPPP---PSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGH 822
Score = 38.9 bits (89), Expect = 0.013
Identities = 28/107 (26%), Positives = 39/107 (36%), Gaps = 13/107 (12%)
Query: 311 TAPVSQPENKPESKPGPVGPELPPGHIPIQVIRKEVDSKPVSQKPPPPSEKVEVKVPPAP 370
T S P +P P + P P V + ++ PP P ++ P P
Sbjct: 199 TTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQP---LQTPPPVPP 255
Query: 371 VPCPPPSPGPSAVPSSPKSVATE----------ERAAPSTAPAEATP 407
P PPP+P P V S P +A +R A +T P P
Sbjct: 256 QPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDP 302
Score = 38.9 bits (89), Expect = 0.013
Identities = 77/340 (22%), Positives = 111/340 (32%), Gaps = 48/340 (14%)
Query: 63 PSSANGPSREGSRLPPAREGHPVYPQLRPGYIPIPVLHEGAENRQVHPFHVYPQPGMQRF 122
P + PS + LPP + P P + P P+L + P PQ ++
Sbjct: 867 PQQPSRPSNRAAALPP-KPARP--PAVSPALTQTPLLPQP-------PMAQPPQVLLEDE 916
Query: 123 RTEAAAAAPQRSQSPLRGMPETTQPDKQCGQVAAAAAAQPPASHGPERSQSPAASDCSSS 182
A + Q L+ + + P V + PP P S
Sbjct: 917 EPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPS---VQQQLQQQ 973
Query: 183 SSSASLPSSGRSSLGSHQLPRGYISIPVI----HEQNVTRPAAQPSFH----QAQKTHYP 234
P HQ P + + + H Q P Q H Q P
Sbjct: 974 PPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQP 1033
Query: 235 A--QQGEYQTHQPVYHKIQGDDWE-------PRPLRAASPFRSSVQGASSREGSPARSST 285
A QQ H P +HK D + P PL SP S Q + + P ++
Sbjct: 1034 AKPQQVIQHHHSPRHHK--SDPYSTGHLREAPSPLMIHSPQMSQFQSLT-HQSPPQQNVQ 1090
Query: 286 P----LHSPSPIRVHTVV----DRPQQPMTHRETAPVS---QPENKPESKPGPV----GP 330
P L + S ++ +V ++ P+ E S +P PES PV P
Sbjct: 1091 PKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRP 1150
Query: 331 ELPPGHIPIQVIRKEVDSKPVSQKPPPPSEKVEVKVPPAP 370
E+ P + VIR + P P +K E K P AP
Sbjct: 1151 EMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQEPKTPVAP 1190
Score = 32.7 bits (73), Expect = 0.93
Identities = 67/298 (22%), Positives = 109/298 (36%), Gaps = 40/298 (13%)
Query: 147 PDKQCGQVAAAA--AAQPPASHGPERSQSPAASDCSSSSSSASLPSSGRSSLGSHQLPRG 204
PD+ V A + A PP S S ++SD SS S S++ S + +L
Sbjct: 458 PDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQE- 516
Query: 205 YISIPVIHEQNVTRPAAQPSFHQAQKTHYPAQQGEYQTH---QPVYHKIQGDDWEPRPLR 261
+ +HEQ +QP ++ +K ++ + + H + V + EP P
Sbjct: 517 --QLKAVHEQ--LAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPP-- 570
Query: 262 AASPFRSSVQGASSREGSPARSSTPLHSPSPIRVHTVVDRPQQPMTHRETAPVSQPENK- 320
+ + + SS + P+ S P + + +PM++ E +S NK
Sbjct: 571 -----KKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKL 625
Query: 321 PESKPGPV-------GPELP---PGHIPIQV------IRKEVDSKPVS---QKPPPPSEK 361
P K G V P L P I I +E++ S +K P +EK
Sbjct: 626 PGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEK 685
Query: 362 VEVKVPPAPVPCPPPSPGPSAVPSSPKSVATEERAAPSTAPAEATPPKPGEAEAPPKH 419
V+V + + S S SS S + E + AP PG + H
Sbjct: 686 VDVIAGSSKMKGFSSSESES---SSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHH 740
Score = 31.6 bits (70), Expect = 2.1
Identities = 39/169 (23%), Positives = 67/169 (39%), Gaps = 38/169 (22%)
Query: 263 ASPFRSSVQGASSREGSPARSSTPLHSPSPIR------------------VHTVVDRPQQ 304
A P S+V +++ +P ++ TP +P P++ V TVV P Q
Sbjct: 189 AKPGVSTVPN-TTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVV--PPQ 245
Query: 305 PMTHRETAPVSQPENKPESKPGPVGPELPPGHI-----PIQV---IRKEVDSK------P 350
P+ +T P P+ +P P P + P I P++ ++++ D+ P
Sbjct: 246 PL---QTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDP 302
Query: 351 VSQKPPPPSEKVEVKVPPAPVPCPPPSPGPSAVPSSPKSVATEERAAPS 399
+ + P P E K+ P P VP S + A E+ + S
Sbjct: 303 IHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVS 351
>gi|47132519 Ras association and pleckstrin homology domains 1
isoform 1 [Homo sapiens]
Length = 1250
Score = 60.1 bits (144), Expect = 5e-09
Identities = 89/364 (24%), Positives = 125/364 (34%), Gaps = 73/364 (20%)
Query: 77 PPAREGHPVYPQLRP---GYIPIPVLHEGAENRQVHPFHVYPQPGMQRFRTEAAAAAPQR 133
PP + V PQ+ G +P P P P PG + + A AP
Sbjct: 689 PPVMQSQSVKPQILVPPNGVVPPPP-----------PPPPPPTPGSAMAQLKPAPCAPSL 737
Query: 134 SQSPLRGMPETTQPDKQCGQVAAAAAAQPPASHGPERSQSPAASDCSSSSSSASLPSSGR 193
Q P + QVA PP P Q+P ++P+
Sbjct: 738 PQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPP-------KPLVTIPAPTS 790
Query: 194 SSLGSHQLPRGYISIPVIHEQNVTRPAAQPSFHQAQKTHYPAQQGEYQTHQPVYHKIQGD 253
+ + + + + P V QP+F + P P K Q
Sbjct: 791 TKTVAPVVTQ---AAPPTPTPPVPPAKKQPAFPASYIPPSPPTP-PVPVPPPTLPKQQSF 846
Query: 254 DWEPRPLRAASPFRSSVQGASSR----EGSPARSSTPLHSPSPIRVHTVVDRPQQPMTHR 309
+P P SP S V+ +S+ PA S PL P P V PQ P
Sbjct: 847 CAKPPP-SPLSPVPSVVKQIASQFPPPPTPPAMESQPL-KPVPANV-----APQSP---- 895
Query: 310 ETAPVSQPENKPESKPGPVGPELPPGHIPIQVIRKEVDSKPVSQKPPPPSEKVEVKVPPA 369
A ++P+ +P S P P P+ PP PPP S V PP+
Sbjct: 896 -PAVKAKPKWQPSSIPVP-SPDFPP--------------------PPPESSLVFPPPPPS 933
Query: 370 PVPCPPPSPGPSAVPSSPKSVATEERAAPSTAPAEATPP-----------KPGEAEAPPK 418
PVP PPP P P+A P+ KS + ++ + +++P PP G PK
Sbjct: 934 PVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPK 993
Query: 419 HPGV 422
P V
Sbjct: 994 RPSV 997
Score = 54.7 bits (130), Expect = 2e-07
Identities = 52/180 (28%), Positives = 74/180 (41%), Gaps = 41/180 (22%)
Query: 279 SPARSSTPLHS--PSPIRVHTVVDRPQQPMTHRETAPVSQPENKPESKPGPVGPELPPGH 336
+P S P S P P+++H V Q +T + AP + P P P P+ P+ PP
Sbjct: 731 APCAPSLPQFSAPPPPLKIHQV-----QHIT--QVAPPTPPP--PPPIPAPLPPQAPPKP 781
Query: 337 ---IPIQVIRKEVD------SKPVSQKPPPPSEK--------VEVKVPPAPVPCPPPS-- 377
IP K V + P P PP++K + P PVP PPP+
Sbjct: 782 LVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLP 841
Query: 378 ----------PGP-SAVPSSPKSVATEERAAPSTAPAEATPPKPGEAEAPPKHPGVLKVE 426
P P S VPS K +A++ P+ E+ P KP A P+ P +K +
Sbjct: 842 KQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAK 901
Score = 44.7 bits (104), Expect = 2e-04
Identities = 46/165 (27%), Positives = 61/165 (36%), Gaps = 29/165 (17%)
Query: 271 QGASSREGSPARSSTPLHSPSPIRVHTVVDRPQ--QPMTHRETAPVSQPENKPESKPGPV 328
+G E S AR + ++ P V + +P+ P T + +P P P P P
Sbjct: 583 RGTQLEESSKARMES-MNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPP 641
Query: 329 GPELPPGHIPIQVIRKEVDSKPV-------------SQ------KPPPP------SEKVE 363
P PP +P Q + P+ SQ KPP P S K +
Sbjct: 642 PPP-PPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQ 700
Query: 364 VKVPPAPVPCPPPSPGPSAVPSSPKSVATEERAAPSTAPAEATPP 408
+ VPP V PPP P P P S + APS A PP
Sbjct: 701 ILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPP 745
Score = 43.1 bits (100), Expect = 7e-04
Identities = 39/144 (27%), Positives = 56/144 (38%), Gaps = 18/144 (12%)
Query: 280 PARSSTPLHSPSPIRV-HTVVDRPQQPMTHRETAPVSQPENKPESKPGPVGPEL--PPGH 336
P++S+ S +P+ V ++ + R Q H + + +P P + V P++ PP
Sbjct: 650 PSQSAPSAGSAAPMFVKYSTITRLQNASQH--SGALFKPPTPPVMQSQSVKPQILVPPNG 707
Query: 337 IPIQVIRKEVDSKPVSQKPPPPSEKVEVKVPPAPVPCPPPSPGPSAVPSSPK--SVATEE 394
+ P PPPP P PC P P SA P K V
Sbjct: 708 VV-----------PPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHIT 756
Query: 395 RAAPSTAPAEATPPKPGEAEAPPK 418
+ AP T P P P +APPK
Sbjct: 757 QVAPPTPPPPPPIPAPLPPQAPPK 780
Score = 40.0 bits (92), Expect = 0.006
Identities = 40/162 (24%), Positives = 62/162 (38%), Gaps = 6/162 (3%)
Query: 268 SSVQGASSREGSPARSSTPLHSPSP-IRVHTVVDRPQQPMTHRETAPVSQPENKPESKPG 326
SS+ + S + + S P+ +R ++V R T + + ES
Sbjct: 541 SSIPESQSNHSNQSDSGVSDTQPAGHVRSQSIVSSVFSEAWKRGTQLEESSKARMESMNR 600
Query: 327 PVGPELPPGHIPIQVIRKEVDSKPVSQKPPPPSEKVEVKVPPAPVPCPPPS-PGPSAVPS 385
P +PP +++ S+P PPPP PP P P P PS PSA +
Sbjct: 601 PYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSA 660
Query: 386 SPK----SVATEERAAPSTAPAEATPPKPGEAEAPPKHPGVL 423
+P S T + A + A PP P ++ P +L
Sbjct: 661 APMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQIL 702
Score = 35.0 bits (79), Expect = 0.19
Identities = 93/445 (20%), Positives = 138/445 (31%), Gaps = 99/445 (22%)
Query: 52 PRVPSEGPKETPSSANGPSREGSRLPPAREGHPVYPQLRPGYIPIPVL--HEGAENRQVH 109
P P P TP SA ++L PA P P L P P L H+ QV
Sbjct: 710 PPPPPPPPPPTPGSAM------AQLKPA----PCAPSLPQFSAPPPPLKIHQVQHITQVA 759
Query: 110 PFHVYPQPGMQRFRTEAAAAAPQRSQSPLRGMPETTQPDKQCGQVAAAAAAQPPASHGPE 169
P P P + A PQ PL +P T K V AA P P
Sbjct: 760 PPTPPPPPPIP------APLPPQAPPKPLVTIPAPTST-KTVAPVVTQAAPPTPTPPVPP 812
Query: 170 RSQSPA--ASDCSSSSSSASLPSSG-----RSSLGSHQLPRGYISIPVIHEQNVTR---P 219
+ PA AS S + +P + S + P +P + +Q ++ P
Sbjct: 813 AKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPP 872
Query: 220 AAQPSFHQAQKTHYPAQQGEYQTH--------QPVYHKIQGDDWEPRPLRAASPFRS--- 268
P+ PA QP + D+ P P ++ F
Sbjct: 873 PTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPP 932
Query: 269 ------------SVQGASSREGSPARSSTPLHSP------------SPIRVHTVVDRPQ- 303
+ + GSP + ++ SP S I+ + + P+
Sbjct: 933 SPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEP 992
Query: 304 -----QPMTHRETAPVSQPENKPESKPGPVGPELP----------PGHIPIQVIRK---- 344
+ + T P E+ P P P P PG + +
Sbjct: 993 KRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPV 1052
Query: 345 ----------EVDSKPVSQKPPPPSEKVEVKVPPAPVPC---PPPSPGPSAVPSSPK--S 389
E S P PPP + E+ +PP +P SP + V P+ S
Sbjct: 1053 LSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWS 1112
Query: 390 VATEERAAPSTAPAEATPPKPGEAE 414
+ ++A P T P + +AE
Sbjct: 1113 KMSVKKAPPPTRPKRNDSTRLTQAE 1137
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 59.7 bits (143), Expect = 7e-09
Identities = 105/511 (20%), Positives = 186/511 (36%), Gaps = 72/511 (14%)
Query: 125 EAAAAAPQRSQSPLRGMPETTQPDKQCGQVAAAAAAQPPASHGPERSQSPAASDCSS--- 181
E A + ++SP E P+K+ A P + PE+ ++ + ++ S
Sbjct: 492 EEAEGGEEETKSP--PAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEK 549
Query: 182 ----SSSSASLPSSGRSSLGSHQLPRGYISIPVIHEQNVTRPAAQPSFHQA-QKTHYPAQ 236
+ A P +S + P + A P+ ++ +K P +
Sbjct: 550 AKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVK 609
Query: 237 Q---GEYQTHQPVYHKIQGDDWEPRPLRAASPFR---SSVQGASSREGSPARSSTPLHSP 290
+ + PV + + P +A SP + S + A S E A+S SP
Sbjct: 610 EEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSP 669
Query: 291 ------------SPIRVHT-VVDRPQQPM------THRETAPVSQPENKPESKPGPVGPE 331
SP++ ++ + P+ + +PV + PE PV E
Sbjct: 670 VKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEE 729
Query: 332 LPPGHIPIQVIRKEVDSKPVSQKPPPPSEKVEVKVPPAPVPCPPPSPGPS-AVPSSPKSV 390
+++E S P K P ++ ++VK P A P + P+ P KS
Sbjct: 730 AKTPEKAKSPVKEEAKS-PEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSP 788
Query: 391 ATEERAAPSTAPA---------EATPPKPGEAEAPPKH---PGVLKVEAILEKVQGLE-Q 437
EE +P A + E PK E ++P K P +KV+ +K + +
Sbjct: 789 VKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAP 848
Query: 438 AVDNFEGKKTDKKYLMIEEYLTKEL---LALDSVDP------EGRADVRQARRDGVRKVQ 488
A E KK KK EE KE + +P E + + ++ + +KV
Sbjct: 849 ATPKTEEKKDSKK----EEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVP 904
Query: 489 T----ILEKLEQKAIDVPGQ-VQVYELQPSNLEADQPLQAIMEMGAVAADKGKKNAGNAE 543
T K+E K P + +V + +P + +A +P + + A K K E
Sbjct: 905 TPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKE----E 960
Query: 544 DPHTETQQPEATAAATSNPSSMTDTPGNPAA 574
++P+ A A + +++ P P A
Sbjct: 961 KAKKPEEKPKTEAKAKEDDKTLSKEPSKPKA 991
Score = 58.5 bits (140), Expect = 2e-08
Identities = 98/443 (22%), Positives = 157/443 (35%), Gaps = 78/443 (17%)
Query: 61 ETPSSANGPSREGSRLP-----PAREGHPVYPQLR-PGYIPIPVLHEGAENRQVHPFHVY 114
++P A P++E ++ P P + PV + + P PV E +V
Sbjct: 579 KSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVK----- 633
Query: 115 PQPGMQRFRTEAAAAAPQRSQSPLRGMPETTQPDKQCGQVAAAAAAQPPASHGPERSQSP 174
P + T+ A +P++++SP + E P+K V A A + PE+++SP
Sbjct: 634 -SPEKAKSPTKEEAKSPEKAKSPEK--EEAKSPEKAKSPVKAEAKS-------PEKAKSP 683
Query: 175 AASDCSSSSSS-------ASLPSSGRSSLGSHQLPRGYISIPVIHEQNVTRPAAQPSFHQ 227
++ S + A P +S + PV E A P +
Sbjct: 684 VKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEE 743
Query: 228 A---QKTHYPAQQGEYQTHQPVYHKIQGDDW----EPRPLRAASPFRSSVQGASSREGSP 280
A +K P + P ++ + P +A SP + V+ SP
Sbjct: 744 AKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVK-------SP 796
Query: 281 ARSSTPLHS---------PSPIRVHTVVDRPQQPMTHRETAPVSQPENKPESKPGPVGPE 331
++ +PL P V + V ++P + V +P K E + P P+
Sbjct: 797 EKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKP----QEVKVKEPPKKAEEEKAPATPK 852
Query: 332 LPPGHIPIQVIRKEVDSKPVSQKPPPPSEKVEVKVPPAPVPCPPPSP--GPSAVPSSPKS 389
K+ K + K P KVE K PA V P S K
Sbjct: 853 TE---------EKKDSKKEEAPKKEAPKPKVEEKKEPA-VEKPKESKVEAKKEEAEDKKK 902
Query: 390 VATEERAAPSTA----------PAEATPPKPGEAEAPPKHPGVLKVEAILEKVQGLEQAV 439
V T E+ AP+ E +P +A+A K EA EK E+
Sbjct: 903 VPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKA 962
Query: 440 DNFEGK-KTDKKYLMIEEYLTKE 461
E K KT+ K ++ L+KE
Sbjct: 963 KKPEEKPKTEAKAKEDDKTLSKE 985
Score = 45.8 bits (107), Expect = 1e-04
Identities = 55/256 (21%), Positives = 95/256 (37%), Gaps = 35/256 (13%)
Query: 195 SLGSHQLPRGYISIPVIHEQNVTRPAAQPSFHQAQKTHYPAQQGEYQTHQPVYHKIQGDD 254
S+ +H + I V+ + + + Q T ++ E + + + +G +
Sbjct: 431 SVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGE 490
Query: 255 WE-----------PRPLRAASPFRSSVQGASSREGSPARSSTPL--HSPSPIRVHTVVDR 301
E P AASP + + SPA + +P + SP V + ++
Sbjct: 491 EEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSP-EK 549
Query: 302 PQQPMTHRETAPVSQPENKPESKPGPVGPELPPGHIPIQVIRKEVDSKPVSQKPPPPSEK 361
+ P +P PE+K PE P +V E P ++ P+E
Sbjct: 550 AKSPAKEEAKSP-------PEAK----SPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEA 598
Query: 362 VEVKVPPAPVPCPPPSPGPSAVP-----SSPKSVATEERAAPST-----APAEATPPKPG 411
+ +PV SP + P SP V + E+A T +P +A P+
Sbjct: 599 KSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKE 658
Query: 412 EAEAPPKHPGVLKVEA 427
EA++P K +K EA
Sbjct: 659 EAKSPEKAKSPVKAEA 674
Score = 42.4 bits (98), Expect = 0.001
Identities = 68/363 (18%), Positives = 121/363 (33%), Gaps = 48/363 (13%)
Query: 55 PSEGPKETPSSANGPSREGSRLPPAREGHPVYPQLRPGYIPIPVLHEGAENRQVHPFHVY 114
P + ++P A P +E ++ P + P PV E +
Sbjct: 683 PVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAK----- 737
Query: 115 PQPGMQRFRTEAAAAAPQRSQSPLRGMPETTQPDKQCGQVAAAAAAQPPASHGPERSQSP 174
P + ++ A +P+++++ PE P K+ A+ PA PE+++SP
Sbjct: 738 -SPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKE--------EARSPADKFPEKAKSP 788
Query: 175 AASDCSSSSSSASLPSSGRSSLGSHQLPRGY-ISIPVIHEQNVTRPAAQPSFHQAQKTHY 233
+ S + S P + ++P+ + PV E+ + +A++
Sbjct: 789 VKEEVKSPEKAKS-PLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKA 847
Query: 234 PA------QQGEYQTHQPVYHKIQGDDWEPRPLRAASPFRSSVQGASSREGSPARSSTPL 287
PA ++ + P + E + P S V+ + TP
Sbjct: 848 PATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTP- 906
Query: 288 HSPSPIRVHTVVD------------RPQQPMTHRETAPVSQPENKPESKPGPVGPELPPG 335
+P +V D P + P + E PE K P
Sbjct: 907 EKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPE 966
Query: 336 HIPIQVIRKEVDSKPVSQKP-PPPSEKVEVKVPPAPVPCPPPSPGPSAVPSSPKSVATEE 394
P + + D K +S++P P +EK E S S P ATE+
Sbjct: 967 EKPKTEAKAKEDDKTLSKEPSKPKAEKAE------------KSSSTDQKDSKPPEKATED 1014
Query: 395 RAA 397
+AA
Sbjct: 1015 KAA 1017
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 58.2 bits (139), Expect = 2e-08
Identities = 86/363 (23%), Positives = 129/363 (35%), Gaps = 32/363 (8%)
Query: 69 PSREGSRLPPAREGHPVYPQLRPGYIPIPVLHEGAENRQVHPFHVYPQPGMQRF--RTEA 126
P EG L P E + PQ ++ PV E + Q H+ PQ R E
Sbjct: 790 PQAEGPHLSPQPEELHLSPQTEEPHLS-PVPEEPCLSPQPEESHLSPQSEEPCLSPRPEE 848
Query: 127 AAAAPQRSQSPLRGMPETTQPDKQCGQVAAAAAAQ--PPASH-------GPERSQSPAAS 177
+ +P+ + PL PE +P ++ GQ A PP G P
Sbjct: 849 SHLSPELEKPPLSPRPE--KPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEP 906
Query: 178 DCSSSSSSASLPSSGRSSLGSHQLPRGYISIPVIHEQNVTRPAAQPSFHQAQKTHYP-AQ 236
S L SG SL +P + P+ + AA P+ + YP
Sbjct: 907 PLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPL---SPIITAAAPPALSPLGELEYPFGA 963
Query: 237 QGEYQTHQPVYHKIQGDDWEPRP-LRAASPFRSSVQGASSREGSPARSSTP-LHSPSPIR 294
+G+ P+ I P P P GSP ++P L P P +
Sbjct: 964 KGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQ 1023
Query: 295 VHTVVDRPQQPMTHRETAPVSQ--PENKPESKPGPVGPELPPGHIPIQVIRKEVDSKPVS 352
++ P + +P SQ P P S P P+ P + + E++++ VS
Sbjct: 1024 CSPLLQHSLVP----QNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVS 1079
Query: 353 QKPPPPSEKVEVKVPPAPV---PCPPPSPGPSAVPSSPKSVATEERAAPSTAPAEATPPK 409
+ P E P+P+ CP PSP P+ S E+ A A + P+
Sbjct: 1080 EPECPALEPSATSPLPSPMGDLSCPAPSPAPAL---DDFSGLGEDTAPLDGIDAPGSQPE 1136
Query: 410 PGE 412
PG+
Sbjct: 1137 PGQ 1139
Score = 48.5 bits (114), Expect = 2e-05
Identities = 77/331 (23%), Positives = 111/331 (33%), Gaps = 42/331 (12%)
Query: 116 QPGMQRFRTEAAAAAPQRSQSPLRGMPET--TQPDKQCGQVAAAAAAQPPASHGPER--- 170
+P ++ E P +SPL PE T P + +++ + PAS PE
Sbjct: 427 EPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPE-ELPASPLPEALHL 485
Query: 171 ----SQSPAASDCSSSSSSASLPSSGRSSLGSHQL--PRGYISIPVIHEQNVTRPAAQPS 224
+SP + S S SS S L L P P + P A P
Sbjct: 486 SRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPL 545
Query: 225 FHQAQKTHYPAQQGEYQTHQPVYHKIQGDDWEPRPLRAASPFRSSVQGASSREG--SPAR 282
+++ E T P P R + P S E SP
Sbjct: 546 SPPFEESPLSPPPEELPTSPP-----------PEASRLSPPPEESPMSPPPEESPMSPPP 594
Query: 283 SSTPLHSP------SPIRVHTVVDRPQQPMTHRETAPVSQPENKPESKPGPVGPELPPGH 336
++ L P SP + + P P R + P PE+ P S P P PP
Sbjct: 595 EASRLFPPFEESPLSPPPEESPLSPP--PEASRLSPP---PEDSPMSPPPEESPMSPPPE 649
Query: 337 I----PIQVIRKEVDSKPVSQKPPPPSEKVEVKVPPAPVPCPPPSPGPSAVPSSPKSVAT 392
+ P+ V+ + S PPP E P A PPP P++ P +
Sbjct: 650 VSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASP 709
Query: 393 EERAAPSTAPAEATP--PKPGEAEAPPKHPG 421
+ + P E +P P P E + P+ G
Sbjct: 710 PPEDSLMSLPLEESPLLPLPEEPQLCPRSEG 740
Score = 48.1 bits (113), Expect = 2e-05
Identities = 83/387 (21%), Positives = 131/387 (33%), Gaps = 37/387 (9%)
Query: 56 SEGPKETPSSANGPSREGSRLPPAREGHPVYPQLRPGYI-PIPVLHEGAENRQVHPFHVY 114
S P+E P+S P E SRL P E P+ P + P P + P
Sbjct: 555 SPPPEELPTS---PPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPP 611
Query: 115 PQPGMQRFRTEAAAAAPQRSQSPLRGMPETT--QPDKQCGQVAAAAAA--------QPPA 164
P+ EA+ +P SP+ PE + P + +++ + P
Sbjct: 612 PEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPL 671
Query: 165 SHGPERSQS---PAASDCSSSSSSASLPSSGRSSLGSHQLPRGYISIPVIHEQNVTRPAA 221
S PE S + P AS S + S S +S+P+ + P
Sbjct: 672 SPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEE 731
Query: 222 QPSFHQAQKTHY-PAQQGEYQTHQPVYHKIQGDDWEPRPLRAASPFRSSVQGASSREGSP 280
+++ H P + + + +P + EP + P +
Sbjct: 732 PQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPH--LSPQPEEPCLCAVPEEPHLS 789
Query: 281 ARSSTPLHSPSPIRVHTVVDRPQQPMTHRETAPVS-----QPENK---PESKPGPVGPEL 332
++ P SP P +H PQ H P QPE P+S+ + P
Sbjct: 790 PQAEGPHLSPQPEELHL---SPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRP 846
Query: 333 PPGHIPIQVIRKEVDSKPVSQKPPPPSEKVEVKVPPAPVPCPPPSPGPSAVPSSPKSVAT 392
H+ E++ P+S +P P E+ P +P PP PS P + +
Sbjct: 847 EESHLS-----PELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALS 901
Query: 393 EERAAPSTAPAEATPPKP-GEAEAPPK 418
E P + E P P GE P+
Sbjct: 902 EPGEPPLSPLPEELPLSPSGEPSLSPQ 928
Score = 47.8 bits (112), Expect = 3e-05
Identities = 34/117 (29%), Positives = 48/117 (41%), Gaps = 24/117 (20%)
Query: 302 PQQPMTHRETAPVSQPENKPESKPGPVGPELPPGHIPIQVIRKEVDSKPVSQKPPPPSEK 361
P+ P H T VS + + S P P P PP P++ P P +
Sbjct: 4886 PEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPS--------------PLAPSPASPPTE 4931
Query: 362 VEVKVPPAPVPCPPPSPGPSAVPSSPKSVATEERAAPSTAPAEATPPKPGEAEAPPK 418
V++P P+ PP P P + SSP+S + RA P P+ GE PP+
Sbjct: 4932 PLVELPTEPL-AEPPVPSPLPLASSPESARPKPRARP---------PEEGEDSRPPR 4978
Score = 46.2 bits (108), Expect = 8e-05
Identities = 94/410 (22%), Positives = 137/410 (33%), Gaps = 56/410 (13%)
Query: 52 PRVPSEGPKETPSSANGPSREGSRLPPAREGHPVYPQLRPGYIPIPVLHEGAENR----Q 107
P+VP++ P + P R P A +P YP P+L GA +R Q
Sbjct: 2165 PQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPML--GASSRPGAGQ 2222
Query: 108 VHPFHVYPQPGMQRFRTEAAAAAPQRSQSPLRGMPETTQPDKQCGQVAAAAAAQPPASHG 167
FH P PG R + + L + P G+ + + PP
Sbjct: 2223 PGEFHTTP-PGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFG-- 2279
Query: 168 PERSQSPAASDCSSSSSSASLPSSGRSSLGSHQLPRG-------YISIPVIHEQNVTRPA 220
+S A + AS PS G +LG P + P + + +T A
Sbjct: 2280 ----ESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRA 2335
Query: 221 AQ-----PSFHQAQKTHYPAQQ--GEYQTHQPVYHKIQGDD------WEPRPLR------ 261
+Q P + PAQ +H ++ D PRP
Sbjct: 2336 SQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESC 2395
Query: 262 AASPFRSSVQGASSR----EGSPARSSTPLHSPSPIRVHTVVDRPQQPMTHRETAPVSQP 317
A P RS SR S + S +PL +P P+ P P + P S+P
Sbjct: 2396 CALPPRSLPSDPFSRVPASPQSQSSSQSPL-TPRPLSAEAFCPSPVTPR-FQSPDPYSRP 2453
Query: 318 ENKPESKPGPVGPELPPGHIPIQVIRKEVDSKPVS--------QKPPPPSEKVEVKVPPA 369
++P+S+ PP P +V K S P P+ ++ KVP
Sbjct: 2454 PSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSG 2513
Query: 370 PVPCPPPSPGPSAVPSSPKSVATEERAAPSTAPAEATPPKPGEAEAPPKH 419
P SPG A +P + A + P+PG PP H
Sbjct: 2514 QPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPG---LPPPH 2560
Score = 42.4 bits (98), Expect = 0.001
Identities = 92/396 (23%), Positives = 133/396 (33%), Gaps = 50/396 (12%)
Query: 55 PSEGPKETP--SSANGPSREGSRLPPAREGHPVYPQLRPGYIPIPVLHEGAENRQVHPFH 112
P E P P SS P E PP E P P L P P + + P
Sbjct: 498 PEESPLSPPPESSPFSPLEESPLSPP--EESPPSPALETPLSPPPEASPLSPPFEESPLS 555
Query: 113 VYPQPGMQRFRTEAAAAAPQRSQSPLRGMPETT--QPDKQCGQVAAAAAAQP-------- 162
P+ EA+ +P +SP+ PE + P + ++ P
Sbjct: 556 PPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEES 615
Query: 163 PASHGPERSQ-SPAASDCSSSSSSASLPSSGRSSLGSHQLPRGYIS--IPVIHEQNVTRP 219
P S PE S+ SP D S P S + S P +S P E ++ P
Sbjct: 616 PLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEV-SRLSPLPVVSRLSPPPEESPLSPP 674
Query: 220 AAQ-PSFHQAQKTHYPAQQGEYQTHQPVYHKIQGDDWEPRPLRAASPFRSSVQGASSREG 278
+ P+ + + + T P P A+ P S+ E
Sbjct: 675 PEESPTSPPPEASRLSPPPEDSPTSPP-----------PEDSPASPPPEDSLMSLPLEE- 722
Query: 279 SPA-----------RSSTPLHSPSPIRVHTVVDRPQQP-MTHRETAPVSQPENKPESKPG 326
SP RS P SP P H + RP++P ++ + P P+ PE
Sbjct: 723 SPLLPLPEEPQLCPRSEGPHLSPRPEEPH-LSPRPEEPHLSPQAEEPHLSPQ--PEEPCL 779
Query: 327 PVGPELPPGHIPIQVIRKEVDSKPVSQKPPPPSEKVEVKVPPAPVPCPPPSPGPSAV-PS 385
PE P H+ Q + +P P +E+ + P PC P P S + P
Sbjct: 780 CAVPEEP--HLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEE-PCLSPQPEESHLSPQ 836
Query: 386 SPKSVATEERAAPSTAPAEATPPKPGEAEAPPKHPG 421
S + + +P PP E PP+ PG
Sbjct: 837 SEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPG 872
Score = 42.4 bits (98), Expect = 0.001
Identities = 76/332 (22%), Positives = 119/332 (35%), Gaps = 33/332 (9%)
Query: 101 EGAENRQVHPFHVYPQPGMQRFRTEAAAAAPQRSQSPLRGMPETTQPDKQCGQVAAAAAA 160
EG Q P + P E+ A P + L G + Q ++
Sbjct: 4039 EGPSTHQGGPLAIGTTP-------ESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQL 4091
Query: 161 QPPASHGPERSQSPAASDCSSSSSSASLPSSGRSSLGS--HQLPRGYISI---PVIHEQN 215
QPP ++ Q + + S L S S S H L + +S+ P QN
Sbjct: 4092 QPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQN 4151
Query: 216 VTRPAAQPSFHQAQKTHYPAQQGEYQTHQPVYHKIQGDDWEPRPLRAASPFRSSVQGASS 275
+ P QP + + + Q + PV QG + R+ +QG +
Sbjct: 4152 LLGPQ-QPMLERPMQNNTGPQPPK---PGPVLQSGQGLPGVGI-MPTVGQLRAQLQGVLA 4206
Query: 276 REGSPARSSTPLHSPSPIRVHTVVDRPQQPMTHRETAPVSQPENKPESKPGPVG--PELP 333
+ +P ++ + + QQ R+T P +P + G +G P+L
Sbjct: 4207 K--NPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLG 4264
Query: 334 PGHIPIQVIRKEVDSKPVSQKPPP-PSEKVEVKVPPAPVPCPPPSPGPSAVPSSPKSVAT 392
P +E+ + P Q PP P+ + P P P P PSSP
Sbjct: 4265 GFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPP-----PSSP----- 4314
Query: 393 EERAAPSTAPAEATPPKPGEAEAPPKHPGVLK 424
+E PS P+ ++ P EA+ PP HPG K
Sbjct: 4315 QEPKRPSQLPSPSSQ-LPTEAQLPPTHPGTPK 4345
Score = 42.0 bits (97), Expect = 0.002
Identities = 83/378 (21%), Positives = 130/378 (34%), Gaps = 62/378 (16%)
Query: 63 PSSANGPSREGSRLPPAREGHPVYPQLRPGYIPIPVLHEGAENRQVHPFHVYPQP-GMQR 121
P + P+ E L A +G P + G++ + ++ P +P G
Sbjct: 375 PEPGDTPTDEPDALYVACQGQP-----KGGHVT------SMQPKEPGPLQCEAKPLGKAG 423
Query: 122 FRTEAAAAAPQRSQSPLRGMPETTQPDKQCGQVAAAAAAQPPASHGPERSQ-SPAASDCS 180
+ E AP + PL PE + + + P S PE S+ SP +
Sbjct: 424 VQLEPQLEAPLNEEMPLLPPPEESP--------LSPPPEESPTSPPPEASRLSPPPEELP 475
Query: 181 SSSSSASLPSSGRSSLGSHQLPRGYISIPVIHEQNVTRPAAQPSFHQAQKTHYPAQQGEY 240
+S LP + S + P P E ++ P F +++ P E
Sbjct: 476 ASP----LPEALHLSRPLEESPLS----PPPEESPLSPPPESSPFSPLEES--PLSPPEE 525
Query: 241 QTHQPVYHKIQGDDWEPRPLRAASPFRSSVQGASSRE--GSPARSSTPLHSPSPIRVHTV 298
P E PL + PF S E SP ++ L SP P
Sbjct: 526 SPPSPALETPLSPPPEASPL--SPPFEESPLSPPPEELPTSPPPEASRL-SPPP------ 576
Query: 299 VDRPQQPMTHRETAPVSQPENK----PESKPGPVGPELPPGHIPIQVIRKEVDSKPVSQK 354
+ P P E +P+S P P + P+ P PP P+ + P +
Sbjct: 577 EESPMSPPP--EESPMSPPPEASRLFPPFEESPLSP--PPEESPLSPPPEASRLSPPPED 632
Query: 355 PP--PPSEKVEVKVPP-----APVPC-----PPPSPGPSAVPSSPKSVATEERAAPSTAP 402
P PP E+ + PP +P+P PPP P + P + A+ + P
Sbjct: 633 SPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPP 692
Query: 403 AEATPPKPGEAEAPPKHP 420
E +P P ++P P
Sbjct: 693 PEDSPTSPPPEDSPASPP 710
Score = 41.2 bits (95), Expect = 0.003
Identities = 88/423 (20%), Positives = 129/423 (30%), Gaps = 110/423 (26%)
Query: 55 PSEGPKETPSSAN--GPSREGSRLPPAREGHPVYPQLRPGYI-PIPVLHEGAENRQVHPF 111
P E P P A+ P E S + P E P+ P + P+PV+ + + P
Sbjct: 612 PEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPL 671
Query: 112 HVYPQPGMQRFRTEAAAAAPQRSQSPLRGMPETTQPDKQCGQVAAAAAAQPPASHGPERS 171
P+ EA+ +P SP PE + PAS PE S
Sbjct: 672 SPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDS-----------------PASPPPEDS 714
Query: 172 QSPAASDCSSSSSSASLPSSGRSSLGSHQLPRG---YISIPVIHEQNVTRPAAQPSFHQA 228
+ S P S G H PR ++S P E +++ A +P
Sbjct: 715 LMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLS-PRPEEPHLSPQAEEPHLSPQ 773
Query: 229 ----------QKTHY-PAQQGEYQTHQPVYHKIQGDDWEPRPLRAASPFRSSVQGASSRE 277
++ H P +G + + QP + EP + P +
Sbjct: 774 PEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPH--LSPVPEEPCLSPQPEES 831
Query: 278 GSPARSSTPLHSPSPIRVHTVVDRPQQPMTHRETAPVSQPENKPESK-----PGPVGPEL 332
+S P SP P H + + P++ R P +P P + P P P L
Sbjct: 832 HLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSL 891
Query: 333 PP----------GHIPIQVIRKEVDSKPVSQK------------PPPPSEKVEVKVPPA- 369
P G P+ + +E+ P + PPP S + PPA
Sbjct: 892 SPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPAL 951
Query: 370 -----------------------------------------PVPCPP----PSPGPSAVP 384
P P PP PSPG P
Sbjct: 952 SPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGP 1011
Query: 385 SSP 387
+SP
Sbjct: 1012 ASP 1014
Score = 39.3 bits (90), Expect = 0.010
Identities = 123/540 (22%), Positives = 183/540 (33%), Gaps = 93/540 (17%)
Query: 55 PSEGPKETPSSANGPSREGSRLPPAREGHPVYPQLRPGYIP---IPVLHEGAENRQ--VH 109
PS P S + G S S L P P + P P +P L GA R
Sbjct: 2589 PSGSPLGPSSGSTGESYGLSPLRP--------PSVLPPPAPDGSLPYLSHGASQRSGITS 2640
Query: 110 PFHVYPQPGMQRFRTEAAAAAPQRSQSPLRGMPETTQPDKQCGQ---------------- 153
P PG + A A P + G+ +T ++ Q
Sbjct: 2641 PVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTL 2700
Query: 154 -------VAAAAAAQPPASHGPERSQSPAASDCSSSSSSASLPSSGRSSLGSHQLPRGYI 206
AAA A PP S G E S SPA S + + S +G LP +
Sbjct: 2701 RQEKETAAAAAGAVGPPGSWGAEPS-SPAFEQLSRGQTPFAGTQDKSSLVG---LPPSKL 2756
Query: 207 SIPVI------HEQNVTR--PAAQPSFHQA-------------QKTHYPAQQGEYQTHQP 245
S P++ + ++R P A PS Q+ YP Q Q
Sbjct: 2757 SGPILGPGSFPSDDRLSRPPPPATPSSMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQ 2816
Query: 246 VYHKIQGDDWEPRPLRAASPFRSSVQGASSRE--GSP-ARSSTPLHSPSPIRVHTVVDRP 302
++ + Q ++ F S+ R+ GSP A ST L P V P
Sbjct: 2817 LWQQQQATAATSMRFAMSARFPSTPGPELGRQALGSPLAGISTRLPGPG-----EPVPGP 2871
Query: 303 QQPMTHRETAPVSQPENKPESKPGP-VGPELPPGHIPI-----QVIRKEVDSKPVSQKPP 356
P E Q P P P GP P P+ ++ + + VS PP
Sbjct: 2872 AGPAQFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVSEDPHRLAPEGLRGLAVSGLPP 2931
Query: 357 -----PPSEKVEVKVPPAPVPCPPPSPGPSAVPSSPKSVATEERAAPSTAPAEATPPKPG 411
PP+ ++ + P P P P + + P S R P A P +
Sbjct: 2932 QKPSAPPAPELNNSLHPTPHTKGPTLPTGLELVNRPPSSTELGRPNPLALEAGKLPCEDP 2991
Query: 412 EAEAP-PKHPGVLKVEAILEKVQGLEQA-----VDNFEGKKTDKKYLMIEEYLT-KELLA 464
E + H + E + G++ A + E +T+ +L ++ L E
Sbjct: 2992 ELDDDFDAHKALEDDEELAHLGLGVDVAKGDDELGTLENLETNDPHL--DDLLNGDEFDL 3049
Query: 465 LDSVDPE-GRADVRQARRDGVRKVQTILEKLEQKAI---DVPGQVQVYELQPSNLEADQP 520
L DPE D + + +R V++ EK E++A+ PG + E P +A +P
Sbjct: 3050 LAYTDPELDTGDKKDIFNEHLRLVESANEKAEREALLRGVEPGPLGPEERPPPAADASEP 3109
Score = 35.8 bits (81), Expect = 0.11
Identities = 74/352 (21%), Positives = 118/352 (33%), Gaps = 64/352 (18%)
Query: 97 PVLHEGAENRQVHPFH-VYPQPGMQRFRTEAAAAAPQRSQSPLRGMPETTQPDKQCGQVA 155
P L + +NR H + V Q Q + +++ P + QP
Sbjct: 2059 PYLQKAKDNRAAHRINKVQKQAESQINKQTKVGDIARKTDRPALHLRIPPQP-------- 2110
Query: 156 AAAAAQPPASHGPERSQSPAASDCSSSSSSASLPSSGRSSLGSHQLPRGYISIPVIHEQN 215
A + PPA+ SP S+S+ L S G ++ +P Q
Sbjct: 2111 GALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLP---PQV 2167
Query: 216 VTRPAAQPSFHQAQKTHYPAQQGEYQTHQPVYHKIQGDDWEPRPLRAASPFRSSVQGASS 275
+ +Q F A YP + + T P Y P P +P + + GASS
Sbjct: 2168 PAQVPSQDPFGLAPA--YPLEP-RFPTAPPTY--------PPYPSPTGAPAQPPMLGASS 2216
Query: 276 REGS-------PARSSTPLHSPSPIRVHTVVDRPQQPMTHRETAPVSQ-----PENKPES 323
R G+ TP H PS +P+ P P S ++P
Sbjct: 2217 RPGAGQPGEFHTTPPGTPRHQPSTPDPFL---KPRCPSLDNLAVPESPGVGGGKASEPLL 2273
Query: 324 KPGPVGPELPPGHIPIQVIRKEVDSKPVSQKPP------PPSEK-----VEVKVPPAPVP 372
P P G ++V ++E+ + S PP PS +E+K P
Sbjct: 2274 SPPPFGESRKA----LEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDV--- 2326
Query: 373 CPPPSPGPSAVPSSPKSVATEERAAPSTAPAEATPPKPGEAEAPPKHPGVLK 424
P +P++ E ++ + PP A +PP HP + +
Sbjct: 2327 --------FKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFR 2370
Score = 35.8 bits (81), Expect = 0.11
Identities = 34/130 (26%), Positives = 52/130 (40%), Gaps = 30/130 (23%)
Query: 301 RPQQPMTHRETAPVSQPENKPESKPGP-VGPELPPGHIPIQVIRKEVDSKPVSQKPPPPS 359
RPQ+P + AP S P + +PG P P P++ +P PP
Sbjct: 2348 RPQEPPPAQALAP-SPPSHPDIFRPGSYTDPYAQP---------------PLTPRPQPPP 2391
Query: 360 EKVEVKVPPAPVPCPPPSPGPSAVPSSPKSVATEER-------AAPSTAPAEATP--PKP 410
+ +PP +P P S VP+SP+S ++ + +A + P+ TP P
Sbjct: 2392 PESCCALPPRSLPSDP----FSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSP 2447
Query: 411 GEAEAPPKHP 420
PP P
Sbjct: 2448 DPYSRPPSRP 2457
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 57.8 bits (138), Expect = 3e-08
Identities = 44/135 (32%), Positives = 58/135 (42%), Gaps = 4/135 (2%)
Query: 301 RPQQPMTHRETAPVSQPENKPESKPGPVGPELPPGHIPIQVIRKEVDSKPVSQKPPPPSE 360
+P+ P AP K P P PE+PP +P +V + V K V + PP E
Sbjct: 10517 KPEAPPPKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVP-EVPKAAVPEKKVPEAIPPKPE 10575
Query: 361 KVEVKVPPAPVPCPPPSPGPSAVPSSPKSVATEERAAP-STAPAEATP-PKPGEAEAPP- 417
+VP AP P P+A P P+ + AP P + P P P + E PP
Sbjct: 10576 SPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPPT 10635
Query: 418 KHPGVLKVEAILEKV 432
K P V KV +KV
Sbjct: 10636 KVPEVPKVAVPEKKV 10650
Score = 56.6 bits (135), Expect = 6e-08
Identities = 58/206 (28%), Positives = 78/206 (37%), Gaps = 15/206 (7%)
Query: 226 HQAQKTHYPAQQGEYQTHQPVYHKIQGDDWEPRPLRAASPFRSSVQGASSREGSPARSST 285
H+ +K H + E + + V+ K + P P + R+ PA+
Sbjct: 10413 HRVEKVHRVIEVFEAEEVE-VFEKPKAPPKGPEISEKIIPPKKPPTKVVPRKEPPAKVP- 10470
Query: 286 PLHSPSPIRVHTVVDRPQQPMTHRETAPVSQPENK--PESK---PGPVGPELPPGHIPIQ 340
P I V V P++P P P + PE K P PE PP +P +
Sbjct: 10471 --EVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVPVPPAKKPEAPPPKVP-E 10527
Query: 341 VIRKEVDSKPVSQKPPPPSEKVEVKVPPAPVPCPPPSPGPSAVPSSPKSVATEERAAPST 400
++ V K V PP E KVP P P P A+P P+S E
Sbjct: 10528 APKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPE----VPE 10583
Query: 401 APAEATPPKPGEAEAPPKHPGVLKVE 426
AP E P K A APPK P V V+
Sbjct: 10584 APKEVVPEKKVPA-APPKKPEVTPVK 10608
Score = 54.3 bits (129), Expect = 3e-07
Identities = 58/198 (29%), Positives = 85/198 (42%), Gaps = 36/198 (18%)
Query: 292 PIRVHTVVDRPQQPMTHRETAPVSQPENKPESKPG--PVGPELPPGHIPIQVIRKE---- 345
P++V V P++P+ E PV P+ K E+ P P P+ P +P+ + +KE
Sbjct: 9947 PVKVPEV---PRKPVPE-EKKPVPVPKKK-EAPPAKVPEVPKKPEEKVPVLIPKKEKPPP 10001
Query: 346 -----VDSKPVSQKPPPPSEKVEVKVPPAPVP-----------CPPPSP-----GPSAVP 384
V KPV ++ P +V+ PPA VP P P+P P+ VP
Sbjct: 10002 AKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVP 10061
Query: 385 SSPKSVATEE-RAAPSTAPAEATPPKPGEAEAPPKHPGVLKVEAILEKVQGLEQAVDNFE 443
PK + EE + P EA PPK + P P L E E+V E+ V E
Sbjct: 10062 EVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQE---EEVLFEEEIVPEEE 10118
Query: 444 GKKTDKKYLMIEEYLTKE 461
+++ L EE + E
Sbjct: 10119 VLPEEEEVLPEEEEVLPE 10136
Score = 53.9 bits (128), Expect = 4e-07
Identities = 41/131 (31%), Positives = 52/131 (39%), Gaps = 13/131 (9%)
Query: 302 PQQPMTHRETAPVSQPENKPESKPGPVGPELPPGHIPIQVIRKEVDSKPVSQKPPPPSEK 361
P +P + P + E PE K P P P P++V + P + P PP +K
Sbjct: 10571 PPKPESPPPEVPEAPKEVVPEKKV-PAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKK 10629
Query: 362 VEV---KVPPAPVPCPPPSPGPSAVPSSPKSVATE-----ERAAPSTAPAEAT----PPK 409
EV KVP P P P A+P P+S E E A PAE P
Sbjct: 10630 PEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAA 10689
Query: 410 PGEAEAPPKHP 420
P + PPK P
Sbjct: 10690 PPQVTVPPKKP 10700
Score = 52.0 bits (123), Expect = 1e-06
Identities = 63/247 (25%), Positives = 99/247 (40%), Gaps = 35/247 (14%)
Query: 292 PIRVHTVVDRPQQPMTHRETAPVSQPENKPESKPGPVGPELPPGHIPIQVIRKEVDSKPV 351
P+ V V+ P + PV PE K P P E PP +P +V +K + P
Sbjct: 10018 PVPVPKKVEAPPAKVPEVPKKPV--PEKKVPV-PAPKKVEAPPAKVP-EVPKKLI---PE 10070
Query: 352 SQKPPPPSEKVEVKVPPAPVPCP-PPSPGPSAVPSSPKSVATEERAAPSTAPAEATPPKP 410
+KP P +KVE PP VP P P P A+P + + EE E P
Sbjct: 10071 EKKPTPVPKKVEA--PPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEEVLPEEEEVLP 10128
Query: 411 GEAEAPPKHPGVLKVEAILEKVQGLEQAVDNFEGKKTDKKYLMIEEYLTKELLALDSVDP 470
E E P+ VL E E++ E+ V +++Y+ EE E L V P
Sbjct: 10129 EEEEVLPEEEEVLPEE---EEIPPEEEEV------PPEEEYVPEEEEFVPEEEVLPEVKP 10179
Query: 471 ----------------EGRADVRQARRDGVRKVQTILEKLEQKAIDVPGQVQVYELQPSN 514
E + + + KV + +K+E+K I +P + +V ++ +
Sbjct: 10180 KVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEKRIILPKEEEVLPVEVTE 10239
Query: 515 LEADQPL 521
++P+
Sbjct: 10240 EPEEEPI 10246
Score = 49.3 bits (116), Expect = 1e-05
Identities = 47/144 (32%), Positives = 59/144 (40%), Gaps = 19/144 (13%)
Query: 330 PELPPGHIPIQVIRKEVDSKPVSQKPPPPSEKVEVK-VPPAPVPCPPPS---PGPSAVPS 385
PE P IP+ K V +PV KP P KV K VP VP P P P P VP
Sbjct: 9789 PEKP---IPV----KPVPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKPPPPKVPE 9841
Query: 386 SPKSV--------ATEERAAPSTAPAEATPPKPGEAEAPPKHPGVLKVEAILEKVQGLEQ 437
PK V T+ T PA P KP A K P K A +V + +
Sbjct: 9842 EPKKVFEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPK 9901
Query: 438 AVDNFEGKKTDKKYLMIEEYLTKE 461
++ E ++ +EEYL +E
Sbjct: 9902 ELEPEEVAFEEEVVTHVEEYLVEE 9925
Score = 48.1 bits (113), Expect = 2e-05
Identities = 49/160 (30%), Positives = 65/160 (40%), Gaps = 29/160 (18%)
Query: 297 TVVDRPQQP--MTHRETAPVSQPENKPESKPGPVGPELPPGHIPIQVIRKEVDSKPVSQK 354
T V P+ P + + PV P+ KPE P V PE+P +P + + + + KP S
Sbjct: 10605 TPVKVPEAPKEVVPEKKVPVPPPK-KPEVPPTKV-PEVPKVAVPEKKVPEAIPPKPESPP 10662
Query: 355 P------------PPPSEKVEVKVPPAP--VPCPPPSPGPSAVPSSPKSVATEERAAP-- 398
P PP+E VE P AP V PP P P +P VA + P
Sbjct: 10663 PEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPE--KKAPAVVAKKPELPPVK 10720
Query: 399 -STAPAEATPPK------PGEAEAPPKHPGVLKVEAILEK 431
P E P K P + EAPP + E + EK
Sbjct: 10721 VPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEK 10760
Score = 47.4 bits (111), Expect = 4e-05
Identities = 97/422 (22%), Positives = 150/422 (35%), Gaps = 50/422 (11%)
Query: 52 PRVPSEGPKETPSSANG--PSREGSRLPPAR-EGHPV-YPQLRPGYIP---IPVLHEGAE 104
P P P E P + P ++ PP + E PV P+ +P +PV +
Sbjct: 10571 PPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPV--PPPK 10628
Query: 105 NRQVHPFHVYPQPGMQRFRTEAAAAAPQRSQSPLRGMPETTQPDKQCGQVAAAAAAQPPA 164
+V P V P + + A P + +SP PE + ++ A +PPA
Sbjct: 10629 KPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESP---PPEVFEEPEE------VALEEPPA 10679
Query: 165 SHGPERSQSPAASDCSSSSSSASLPSSGRSSLGSHQLPRGYISIPVIHEQNVTR---PAA 221
E PAA + +P ++ + + + +P + ++ V P
Sbjct: 10680 EVVEE--PEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLV 10737
Query: 222 QPSFHQAQKTHYPAQQGEYQTHQPVYHKIQGDDWEPRPLRAASPFRSSVQGASSREGSPA 281
P +A P E + V + E P + + V P
Sbjct: 10738 VPKKPEAPPAKVPEVPKEVVPEKKVAVPKKP---EVPPAKVPEVPKKPVLEEKPAVPVPE 10794
Query: 282 RSSTPLHSPSPIRVHTVVDRPQQPMTHRETAPVSQPENKPESKPGPVGPELPPGHIPIQV 341
R+ +P P + P++ + E PV E + P P PE P IP +
Sbjct: 10795 RAESP---PPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKK 10851
Query: 342 IRKEVDSKPVSQKPPPPS-EKVEVKVPPAPVPCPPPSPGPSAVPSSPKSVATEERAAPST 400
+ V KP + PPP E +V P P PPP P P+ PK E+
Sbjct: 10852 V--PVIKKP--EAPPPKEPEPEKVIEKPKLKPRPPPPP-----PAPPKEDVKEKIFQLKA 10902
Query: 401 APAEATPPKPGEAEAPPKHPGVLKVEAILEKVQGLEQAVDNF--EGKKTDKKYLMIEEYL 458
P + P KP E KVE KV G E+ V E K K+ ++++ L
Sbjct: 10903 IPKKKVPEKPQVPE---------KVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVL 10953
Query: 459 TK 460
K
Sbjct: 10954 RK 10955
Score = 46.2 bits (108), Expect = 8e-05
Identities = 94/437 (21%), Positives = 157/437 (35%), Gaps = 73/437 (16%)
Query: 131 PQRSQSPLRGMPETTQPDKQCGQVAAAAAAQPPASHGPERSQSPAASDCSSSSSSASLPS 190
P++ ++P +PE + ++ V +PP + PE + P + + +
Sbjct: 9968 PKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEA 10027
Query: 191 SGRSSLGSHQLPRGYISIPVIHEQNVTRPAAQPSFHQAQKTHYPAQQGEYQTHQPVYHKI 250
+ P +PV + V P A+ + K P E + PV K+
Sbjct: 10028 PPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAK--VPEVPKKLIP----EEKKPTPVPKKV 10081
Query: 251 QG------DDWEPRPLRAASPFRSSVQGASSREGSPARSSTPLHSPSPIRVHTVVDRPQQ 304
+ EP P+ A P V E P P V+ ++
Sbjct: 10082 EAPPPKVPKKREPVPVPVALPQEEEV--LFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEE 10139
Query: 305 PMTHRETAPVSQPENKPESKPGP----------VGPELPPG---HIPIQVIRKEVDSK-- 349
+ E P + E PE + P V PE+ P P+ I+K+V K
Sbjct: 10140 VLPEEEEIPPEEEEVPPEEEYVPEEEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKV 10199
Query: 350 --PVSQKPPPPS-----EKVEVK---------VPPAPVPCPPPSP--GPSAVPSSPKSVA 391
P ++ PP +KVE K V P V P +P P S+
Sbjct: 10200 VIPKKEEAPPAKVPEVPKKVEEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIE 10259
Query: 392 TEERAAPSTAP-------AEATPPKPGEAEAPP----KHPGVLKVEAILEKVQGLEQAVD 440
E AP P EA P P + EAPP K KV ++K + V
Sbjct: 10260 EVEEVAPPRVPEVIKKAVPEAPTPVPKKVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVP 10319
Query: 441 NFEGKKTDKKYLMIEEYLTKELLALDSVDP-EGRADVRQA-----RRDGVRKVQTILEKL 494
K +KK L+ ++ ++V P +GR + + R++ V K + LE +
Sbjct: 10320 EVPKKVPEKKVLVPKK---------EAVPPAKGRTVLEEKVSVAFRQEVVVKERLELEVV 10370
Query: 495 EQKAIDVPGQVQVYELQ 511
E + ++P + + +E++
Sbjct: 10371 EAEVEEIPEEEEFHEVE 10387
Score = 46.2 bits (108), Expect = 8e-05
Identities = 40/120 (33%), Positives = 52/120 (43%), Gaps = 15/120 (12%)
Query: 310 ETAPVSQPENKPESKPGPVGPELPPGHIPIQVIRKEVDSKPVSQKPPPPSEKVEVKVPPA 369
E P +P+ K E P PE PP P++ + +K +K P P++ E+K P
Sbjct: 10959 EEEPKVEPK-KLEKVKKPAVPEPPPPK-PVEEVEVPTVTKR-ERKIPEPTKVPEIK-PAI 11014
Query: 370 PVPCPPPSPGPSAVPSSPKSVATEERAAPSTAP---------AEATPPKPGEAEAPPKHP 420
P+P P P P P A + K E P AP AEA PK E A PK P
Sbjct: 11015 PLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTVPVVGKKAEAKAPK--EEAAKPKGP 11072
Score = 43.9 bits (102), Expect = 4e-04
Identities = 43/207 (20%), Positives = 80/207 (38%), Gaps = 8/207 (3%)
Query: 348 SKPVSQKPPPPSEKVEVKVPPAP-VPCPPPSPGPSAVPSSPKSVATEERAAPSTAPAEAT 406
SK V +P +E+ E K+ P +P P P+ VP +PK + E++ P+ P +
Sbjct: 9544 SKRVEAEPAEVTERQEKKIVLKPKIPAKIEEPPPAKVPEAPKKIVPEKK-VPAPVPKKEK 9602
Query: 407 PPKPGEAEAPPKHPGVLKVEAILEKVQGLEQAVDNFEGKKTDKKYLMIEEYLTKELLALD 466
P P E P K KV + K++ + K T++ + +E +
Sbjct: 9603 VPPPKVPEEPKKPVPEKKVPPKVIKME------EPLPAKVTERHMQITQEEKVLVAVTKK 9656
Query: 467 SVDPEGRADVRQARRDGVRKVQTILEKLEQKAIDVPGQVQVYELQPSNLEADQPLQAIME 526
P+ R R KV + K E++ + + ++ + + P +
Sbjct: 9657 EAPPKARVPEEPKRAVPEEKVLKLKPKREEEPPAKVTEFRKRVVKEEKVSIEAPKREPQP 9716
Query: 527 MGAVAADKGKKNAGNAEDPHTETQQPE 553
+ V + K+ A E+ Q+ E
Sbjct: 9717 IKEVTIMEEKERAYTLEEEAVSVQREE 9743
Score = 43.1 bits (100), Expect = 7e-04
Identities = 42/157 (26%), Positives = 67/157 (42%), Gaps = 26/157 (16%)
Query: 289 SPSPIRVHTVVDRPQQPMTHRETAPV--SQPENKPESKPGPVGPELPPGHIPIQVIRKEV 346
+P V++V+ R + R TA + + E K E KP P++P +PI +
Sbjct: 8896 TPDDEGVYSVIARLEPRGEARSTAELYLTTKEIKLELKP----PDIPDSRVPIPTM---- 8947
Query: 347 DSKPVSQKPPPPSEKVEVKVPPAPVPCPPP---SPGPSAVPSSPKSVATEERAAPSTAPA 403
P+ + PP E V PP P+ P P P P + + K+V + + + P
Sbjct: 8948 ---PI--RAVPPEEIPPVVAPPIPLLLPTPEEKKPPPKRIEVTKKAVKKDAKKVVA-KPK 9001
Query: 404 EATP-------PKPGEAEAPPKHPGVLKVEAILEKVQ 433
E TP P P P K P ++ V + E+V+
Sbjct: 9002 EMTPREEIVKKPPPPTTLIPAKAPEIIDVSSKAEEVK 9038
Score = 42.7 bits (99), Expect = 9e-04
Identities = 48/198 (24%), Positives = 73/198 (36%), Gaps = 38/198 (19%)
Query: 298 VVDRPQQPMTHRETAPVSQPENK----PESK---PGPVGPELPPGHIPIQ----VIRKEV 346
+V +P+ P E P PE PE K P P ++PP +P + V K+V
Sbjct: 9562 IVLKPKIPAKIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPKVPEEPKKPVPEKKV 9621
Query: 347 DSKPVSQKPPPPSEKVE----------VKVPPAPVPCPPPSPGPSAVPSSPKSVATEERA 396
K + + P P++ E V V PP + VP PK EE+
Sbjct: 9622 PPKVIKMEEPLPAKVTERHMQITQEEKVLVAVTKKEAPPKA----RVPEEPKRAVPEEKV 9677
Query: 397 APSTAPAEATPP-------------KPGEAEAPPKHPGVLKVEAILEKVQGLEQAVDNFE 443
E PP + EAP + P +K I+E+ + +
Sbjct: 9678 LKLKPKREEEPPAKVTEFRKRVVKEEKVSIEAPKREPQPIKEVTIMEEKERAYTLEEEAV 9737
Query: 444 GKKTDKKYLMIEEYLTKE 461
+ +++Y EEY KE
Sbjct: 9738 SVQREEEYEEYEEYDYKE 9755
Score = 42.0 bits (97), Expect = 0.002
Identities = 57/238 (23%), Positives = 92/238 (38%), Gaps = 42/238 (17%)
Query: 206 ISIPVIHEQNVTRPAAQPSF----HQAQKTHYPAQQGEYQTHQPVYHKIQGDDWEPRPLR 261
+ +P +H + + + F + P Q E T + ++ I EP P
Sbjct: 9230 VKVPAVHTKKMVISEEKMFFASHTEEEVSVTVPEVQKEIVTEEKIHVAIS-KRVEPPPKV 9288
Query: 262 AASPFRSSVQGASSREGSPARSSTPLHSPSPIRVHTVVDRPQQPMTHRETAPVSQPENKP 321
P + + + E +P + P+P V + P++P+ E PV P+ +P
Sbjct: 9289 PELPEKPAPE-----EVAPVPIPKKVEPPAP----KVPEVPKKPVPE-EKKPVPVPKKEP 9338
Query: 322 ESKPG-PVGPE--LPPGHIPIQVIRK---------EVDSKPVSQKP----------PPPS 359
+ P P P+ +P IP+ V +K EV V+++ PPP+
Sbjct: 9339 AAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPA 9398
Query: 360 --EKVEVKVPPAPVPCPPPS---PGPSAVPSSPKSVATEERAAPSTAPAEATPPKPGE 412
E + KVP P P P P VP+ PK EE+ A A+ PP E
Sbjct: 9399 VPEIPKKKVPEERKPVPRKEEEVPPPPKVPALPKKPVPEEKVAVPVPVAKKAPPPRAE 9456
Score = 42.0 bits (97), Expect = 0.002
Identities = 87/397 (21%), Positives = 138/397 (34%), Gaps = 76/397 (19%)
Query: 52 PRVPSEGPKETPSSANGPSREGSRLPPAREGHPVYPQL-------------RPGYIPIPV 98
P+ P +GP E P + +++ P +E P++ +P
Sbjct: 10436 PKAPPKGP-EISEKIIPPKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTK 10494
Query: 99 LHEGAENRQVHPFHVYPQPGMQRFRTEAAAAAPQRSQSPLRGMPE--TTQPDKQCGQVAA 156
+ E ++V P P P ++ A P+ ++P +PE P + +V
Sbjct: 10495 VPEVLPPKEVVPEKKVPVPPAKK----PEAPPPKVPEAPKEVVPEKKVPVPPPKKPEVPP 10550
Query: 157 AAAAQPPASHGPERSQSPAASDCSSSSSSASLPSSGRSSLGSHQLPRGYISIPVIHEQNV 216
+ P + PE+ + P A S +P + + V+ E+ V
Sbjct: 10551 TKVPEVPKAAVPEK-KVPEAIPPKPESPPPEVPEAPKE---------------VVPEKKV 10594
Query: 217 TRPAAQPSFHQAQKTHYPAQQGEYQTHQPVYHKIQGDDWEPRPLRAASPFRSSVQGASSR 276
PAA P + P E + V P P + + +V
Sbjct: 10595 --PAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVP-PTKVPEVPKVAVPEKKVP 10651
Query: 277 EGSPARSSTP----LHSPSPIRVHT----VVDRPQQPMTHRETAPVSQPENKPESKPGPV 328
E P + +P P + + VV+ P+ + T P +P PE K V
Sbjct: 10652 EAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPV--PEKKAPAV 10709
Query: 329 ---GPELPPGHIPIQVIRKEVDSKPVSQKPPPPSEKVEVKVPPAPVPCPPPSPGPSAVPS 385
PELPP +P EV + V P +KV + VP P P+ VP
Sbjct: 10710 VAKKPELPPVKVP------EVPKEVV------PEKKVPLVVP------KKPEAPPAKVPE 10751
Query: 386 SPKSVATEERAA----PSTAPAEA--TPPKPGEAEAP 416
PK V E++ A P PA+ P KP E P
Sbjct: 10752 VPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKP 10788
Score = 41.2 bits (95), Expect = 0.003
Identities = 32/137 (23%), Positives = 59/137 (43%), Gaps = 8/137 (5%)
Query: 296 HTVVDRPQQPMTHRETAPVSQPENKPESKPGPVGPELPPGHIPIQVIRKEVDSKPVSQKP 355
+ V++ P++ + + +S+ + E++P V + I +++ P ++ P
Sbjct: 9525 YEVMEEPEEYVVEEKLHIISK---RVEAEPAEVTERQEKKIVLKPKIPAKIEEPPPAKVP 9581
Query: 356 PPPSEKVEVKVPPAPVPCPPPSPGPSAVPSSPKSVATEERAAPSTAPAEATPPKPGEAEA 415
P + V K PAPVP P P VP PK E++ P E +P A+
Sbjct: 9582 EAPKKIVPEKKVPAPVPKKEKVP-PPKVPEEPKKPVPEKKVPPKVIKME----EPLPAKV 9636
Query: 416 PPKHPGVLKVEAILEKV 432
+H + + E +L V
Sbjct: 9637 TERHMQITQEEKVLVAV 9653
Score = 40.0 bits (92), Expect = 0.006
Identities = 74/325 (22%), Positives = 120/325 (36%), Gaps = 47/325 (14%)
Query: 213 EQNVTRPAAQPSFHQAQKTHYP-AQQGEYQTHQP-VYHKIQGDDWEPRPL-RAASPFRSS 269
E +VT P Q +K H +++ E P + K ++ P P+ + P
Sbjct: 9256 EVSVTVPEVQKEIVTEEKIHVAISKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPK 9315
Query: 270 VQGASSREGSPARSSTPLHSPSPIRVHTVVDRPQQPMTH----------RETAPVSQPE- 318
V + + P+ P V + P++P+ +E P PE
Sbjct: 9316 VPEVPKKPVPEEKKPVPVPKKEPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEV 9375
Query: 319 -------------NKPESKPGPVGPELPPGHIPIQ---VIRKEVDSKPVSQKP-----PP 357
+ E P P PE+P +P + V RKE + P + P P
Sbjct: 9376 QKGVVTEEKITIVTQREESPPPAVPEIPKKKVPEERKPVPRKEEEVPPPPKVPALPKKPV 9435
Query: 358 PSEKVEVKVPPAPVPCPPPSPGPSAVPSSPKSVATEERAAPSTAPAEATPPK----PGEA 413
P EKV V VP A PPP S K+V E+R + A P + E
Sbjct: 9436 PEEKVAVPVPVAK-KAPPP-----RAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEV 9489
Query: 414 EAPPKHPGVLKVEAILEKVQGLEQAVDNFEGKKTDKKYL-MIEEYLTKELLALDSVDPEG 472
A + + E + V E+ + E + T+ + + EEY+ +E L + S E
Sbjct: 9490 SAEEEWSYSEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEA 9549
Query: 473 R-ADVRQARRDGVRKVQTILEKLEQ 496
A+V + + + I K+E+
Sbjct: 9550 EPAEVTERQEKKIVLKPKIPAKIEE 9574
Score = 39.3 bits (90), Expect = 0.010
Identities = 37/125 (29%), Positives = 53/125 (42%), Gaps = 17/125 (13%)
Query: 302 PQQPMTHRETAPVSQPENK-PESKPGP-VGPELPPGHIPIQVIRKEVDSKPVSQKPPPPS 359
P +P+ E V++ E K PE P + P +P +P + + +++ + KPPP
Sbjct: 10982 PPKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIP---LPAPEPKPKPEAEVKTIKPPP-- 11036
Query: 360 EKVEVKVPPAPVPCPPPSPGPSAVPSSPKSVATEERAAPSTAPAEATP---PKPGEAEAP 416
VE + P P P G A +PK E AA P + P P P EAE
Sbjct: 11037 --VEPEPTPIAAPVTVPVVGKKAEAKAPK-----EEAAKPKGPIKGVPKKTPSPIEAERR 11089
Query: 417 PKHPG 421
PG
Sbjct: 11090 KLRPG 11094
Score = 38.9 bits (89), Expect = 0.013
Identities = 38/175 (21%), Positives = 67/175 (38%), Gaps = 10/175 (5%)
Query: 290 PSPIRVHTVVDRPQQPMTHRETAPVSQPE----NKPESKPGPVGPELPPGHIPIQVIRKE 345
PS V V + P H + +S+ + + E + PE+ + + I
Sbjct: 9218 PSRTPVQEEVIEVKVPAVHTKKMVISEEKMFFASHTEEEVSVTVPEVQKEIVTEEKIHVA 9277
Query: 346 VDSK--PVSQKPPPPSEKVEVKVPPAPVP--CPPPSPGPSAVPSSPKSVATEERAAPSTA 401
+ + P + P P + +V P P+P PP+P VP P V E++ P
Sbjct: 9278 ISKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKP--VPEEKKPVPVPK 9335
Query: 402 PAEATPPKPGEAEAPPKHPGVLKVEAILEKVQGLEQAVDNFEGKKTDKKYLMIEE 456
A PPK E P + V +K + + +G T++K ++ +
Sbjct: 9336 KEPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQ 9390
Score = 38.9 bits (89), Expect = 0.013
Identities = 80/403 (19%), Positives = 135/403 (33%), Gaps = 35/403 (8%)
Query: 29 KIDPQTGWPFFVDHNSRTTTWNDPRVPSEGPKE----TPSSANGPSREGSRLP--PAREG 82
++ P+ P V P VP E E P P + +P P E
Sbjct: 10727 EVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEE 10786
Query: 83 HPVYPQLRPGYIPIPVLHEGAEN----RQVHPFHVYPQPGMQRFRTEAAAAAPQRSQSPL 138
P P P P ++E E ++ P P P + E P + P
Sbjct: 10787 KPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEE--EEPEVPPPAVPEEPK 10844
Query: 139 RGMPETTQPDKQCGQVAAAAAAQPPASHGPERS-QSPAASDCSSSSSSASLPSSGRSSLG 197
+ +PE P V A PP PE+ + P A + +
Sbjct: 10845 KIIPEKKVP------VIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIF 10898
Query: 198 SHQ-LPRGYI-SIPVIHEQNVTRPAAQPSFHQAQKTHYPAQQGEYQTHQPVYHKIQGDDW 255
+ +P+ + P + E+ P P + + P ++ E + + ++
Sbjct: 10899 QLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPE 10958
Query: 256 EPRPLRAASPFRSSVQGASSREGSPARSSTPLHSPSPIRVHTVVDRPQQPMTHRETAPVS 315
E P + V+ + E P + + P+ + + P + + P+
Sbjct: 10959 EEEP-KVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLP 11017
Query: 316 QPENKPES-------KPGPVGPELPP--GHIPIQVIRKEVDSKPVSQKPPPPSEKVEVKV 366
PE KP+ KP PV PE P + + V+ K+ ++K ++ P K +K
Sbjct: 11018 APEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTVPVVGKKAEAKAPKEEAAKP--KGPIKG 11075
Query: 367 PPAPVPCPPPSPGPSAVPSSPKSVATEERAAPSTAPAEATPPK 409
P P P + P S +E AP T +A P K
Sbjct: 11076 VPKKTPSPIEAERRKLRPGSGGEKPPDE--APFTYQLKAVPLK 11116
Score = 37.7 bits (86), Expect = 0.029
Identities = 31/98 (31%), Positives = 37/98 (37%), Gaps = 13/98 (13%)
Query: 345 EVDSKPVSQKPPPPSEKVEVKVPPA---PVPCPPPSPGPSAVPSSPKSVATEERA----- 396
EV KP K PP ++ K+ P P P P+ VP PK + EE+
Sbjct: 10431 EVFEKP---KAPPKGPEISEKIIPPKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEE 10487
Query: 397 --APSTAPAEATPPKPGEAEAPPKHPGVLKVEAILEKV 432
P T E PPK E P K EA KV
Sbjct: 10488 PRVPPTKVPEVLPPKEVVPEKKVPVPPAKKPEAPPPKV 10525
Score = 37.0 bits (84), Expect = 0.049
Identities = 41/156 (26%), Positives = 58/156 (37%), Gaps = 39/156 (25%)
Query: 309 RETAPVSQPENKPESKPGPVGPELPPGHIP-IQVIRKEVDSKPVSQKPPPPSEKVEVKVP 367
R+ P +PE K E V + P P ++ + E KP +PPPP EV+VP
Sbjct: 10933 RKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVP 10992
Query: 368 ------------------------PAPVPCPPPS------------PGPSAVPSSPKSVA 391
PAP P P P P P+ + ++P +V
Sbjct: 10993 TVTKRERKIPEPTKVPEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPI-AAPVTVP 11051
Query: 392 TEERAAPSTAP-AEATPPKPGEAEAPPKHPGVLKVE 426
+ A + AP EA PK P K P ++ E
Sbjct: 11052 VVGKKAEAKAPKEEAAKPKGPIKGVPKKTPSPIEAE 11087
Score = 35.4 bits (80), Expect = 0.14
Identities = 41/146 (28%), Positives = 58/146 (39%), Gaps = 22/146 (15%)
Query: 292 PIRVHTVVDRPQQPMTHRETAP-VSQPENKPESKPGPVG-PELPPGHIPIQVIRKEVDSK 349
P++ VV + P+ +E AP V PE E +P V E H+ ++ +E +
Sbjct: 9871 PMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKELEPEEVAFEEEVVTHVEEYLVEEEEEYI 9930
Query: 350 PVSQKPPPPSEKVEV---KVP------------PAPVPCPPPSPGPSAVPSSPKSVATEE 394
++ E V V KVP P PVP +P P+ VP PK E
Sbjct: 9931 HEEEEFITEEEVVPVIPVKVPEVPRKPVPEEKKPVPVPKKKEAP-PAKVPEVPKK---PE 9986
Query: 395 RAAPSTAPAEATPPKPGEAEAPPKHP 420
P P + PP P + PK P
Sbjct: 9987 EKVPVLIPKKEKPP-PAKVPEVPKKP 10011
Score = 35.4 bits (80), Expect = 0.14
Identities = 39/126 (30%), Positives = 52/126 (41%), Gaps = 11/126 (8%)
Query: 298 VVDRPQQPMTHRETAPVSQPENKPESKPGPVGPELPPGHIPIQVIRKEVDSKPVSQKPPP 357
V ++PQ P E P+ P E K + PE P V++ + +P ++P
Sbjct: 10908 VPEKPQVP-EKVELTPLKVPGG--EKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKV 10964
Query: 358 PSEKVE-VKVPPAPVPCPPPSPGPSA-VPSSPKSVATEERAAPS-TAPAEATPPKPGEAE 414
+K+E VK P P P PPP P VP +V ER P T E P P A
Sbjct: 10965 EPKKLEKVKKPAVPEP-PPPKPVEEVEVP----TVTKRERKIPEPTKVPEIKPAIPLPAP 11019
Query: 415 APPKHP 420
P P
Sbjct: 11020 EPKPKP 11025
Score = 32.3 bits (72), Expect = 1.2
Identities = 28/91 (30%), Positives = 34/91 (37%), Gaps = 13/91 (14%)
Query: 340 QVIRKEVDSKPVSQKPPPPSEKVEVKVPPAPVPCPPPSPGPSAVPSSPKSVATEERAAPS 399
+V K V S P + P P + E P V P PS PK+V+ E
Sbjct: 32654 RVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPE--------PSHPKAVSPTETKPTP 32705
Query: 400 TAPAEATPPKPGEAEAPPKHPGVLKVEAILE 430
T + P APPK LK EA E
Sbjct: 32706 TEKVQHLP-----VSAPPKITQFLKAEASKE 32731
Score = 31.2 bits (69), Expect = 2.7
Identities = 49/219 (22%), Positives = 80/219 (36%), Gaps = 19/219 (8%)
Query: 302 PQQPMTHRETAPVSQPENKPESKPGPVGPELPPGHIPIQVIRKEVDSKPVSQKPPPPSEK 361
P + + E PV P P P P + PP I + + D+K V KP + +
Sbjct: 8948 PIRAVPPEEIPPVVAPPI-PLLLPTPEEKKPPPKRIEVTKKAVKKDAKKVVAKPKEMTPR 9006
Query: 362 VEVKVPPAPVPCPPPSPGPSAVPSSPKSVATEERAAPSTAPAEATPPKPGEAEAPPKHPG 421
E+ P P P+ P + S K A E + T E K E K
Sbjct: 9007 EEIVKKPPPPTTLIPAKAPEIIDVSSK--AEEVKIMTITRKKEVQKEKEAVYE---KKQA 9061
Query: 422 VLKVEAILEKVQGLEQAVDNFEGKKTDKKYLM------IEEYLTKELLALDSVDPEGRAD 475
V K + + ++ E+ D E + + + E+Y ++ A V E D
Sbjct: 9062 VHKEKRVF--IESFEEPYDELEVEPYTEPFEQPYYEEPDEDYEEIKVEAKKEVHEEWEED 9119
Query: 476 VRQA-----RRDGVRKVQTILEKLEQKAIDVPGQVQVYE 509
+ R +G + + E+ Q+ + Q +VYE
Sbjct: 9120 FEEGQEYYEREEGYDEGEEEWEEAYQEREVIQVQKEVYE 9158
Score = 30.8 bits (68), Expect = 3.5
Identities = 37/153 (24%), Positives = 57/153 (37%), Gaps = 18/153 (11%)
Query: 261 RAASPFRSSVQGASSREGSPARSSTPLHSPSPIRVHTVVDRPQQPMTHRETAPVSQPENK 320
RA S VQG E PA+ + + S + I ++ H + ++ E
Sbjct: 184 RATSTAELLVQG---EEEVPAKKTKTIVSTAQISESRQTRIEKKIEAHFDARSIATVEMV 240
Query: 321 PESKPGPVGPELPPGHIPIQVIRKEVDSKPVSQKPPPPSEKVEVKVPPAPVPCP-PPSPG 379
+ G P P IP KP S+ P PPS + ++ P P SP
Sbjct: 241 IDGAAGQQLPHKTPPRIP---------PKPKSRSPTPPSIAAKAQLARQQSPSPIRHSPS 291
Query: 380 P-----SAVPSSPKSVATEERAAPSTAPAEATP 407
P + PS +SV+ R + S + +P
Sbjct: 292 PVRHVRAPTPSPVRSVSPAARISTSPIRSVRSP 324
>gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Homo
sapiens]
Length = 305
Score = 57.8 bits (138), Expect = 3e-08
Identities = 44/154 (28%), Positives = 57/154 (37%), Gaps = 16/154 (10%)
Query: 287 LHSPSPIRVHTVVDRPQQPMTHRETAPVSQPENKPESKPGPVGPELPPGHIPIQVIRKEV 346
L +P P+ V V P +P PE P S P P PP P+ V+
Sbjct: 92 LLAPRPVAVAVAVSPPLEPAAESLDGLEEAPEQLP-SVPVPAPASTPP---PVPVLAPAP 147
Query: 347 DSKPVSQKPPPPSEKVEVKVPPAPVPCPPPSPGPSAVPSSPKSVATEERAAPSTAPAEAT 406
P P + + PAP P P P+P P+ V AAP+ APA A
Sbjct: 148 APAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPV------------AAPAPAPAPAP 195
Query: 407 PPKPGEAEAPPKHPGVLKVEAILEKVQGLEQAVD 440
P P A AP P + + +G E D
Sbjct: 196 APAPAPAPAPDAAPQESAEQGANQGQRGQEPLAD 229
>gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Homo
sapiens]
Length = 305
Score = 57.8 bits (138), Expect = 3e-08
Identities = 44/154 (28%), Positives = 57/154 (37%), Gaps = 16/154 (10%)
Query: 287 LHSPSPIRVHTVVDRPQQPMTHRETAPVSQPENKPESKPGPVGPELPPGHIPIQVIRKEV 346
L +P P+ V V P +P PE P S P P PP P+ V+
Sbjct: 92 LLAPRPVAVAVAVSPPLEPAAESLDGLEEAPEQLP-SVPVPAPASTPP---PVPVLAPAP 147
Query: 347 DSKPVSQKPPPPSEKVEVKVPPAPVPCPPPSPGPSAVPSSPKSVATEERAAPSTAPAEAT 406
P P + + PAP P P P+P P+ V AAP+ APA A
Sbjct: 148 APAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPV------------AAPAPAPAPAP 195
Query: 407 PPKPGEAEAPPKHPGVLKVEAILEKVQGLEQAVD 440
P P A AP P + + +G E D
Sbjct: 196 APAPAPAPAPDAAPQESAEQGANQGQRGQEPLAD 229
>gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo
sapiens]
Length = 316
Score = 57.8 bits (138), Expect = 3e-08
Identities = 44/154 (28%), Positives = 57/154 (37%), Gaps = 16/154 (10%)
Query: 287 LHSPSPIRVHTVVDRPQQPMTHRETAPVSQPENKPESKPGPVGPELPPGHIPIQVIRKEV 346
L +P P+ V V P +P PE P S P P PP P+ V+
Sbjct: 103 LLAPRPVAVAVAVSPPLEPAAESLDGLEEAPEQLP-SVPVPAPASTPP---PVPVLAPAP 158
Query: 347 DSKPVSQKPPPPSEKVEVKVPPAPVPCPPPSPGPSAVPSSPKSVATEERAAPSTAPAEAT 406
P P + + PAP P P P+P P+ V AAP+ APA A
Sbjct: 159 APAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPV------------AAPAPAPAPAP 206
Query: 407 PPKPGEAEAPPKHPGVLKVEAILEKVQGLEQAVD 440
P P A AP P + + +G E D
Sbjct: 207 APAPAPAPAPDAAPQESAEQGANQGQRGQEPLAD 240
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 57.8 bits (138), Expect = 3e-08
Identities = 100/454 (22%), Positives = 147/454 (32%), Gaps = 109/454 (24%)
Query: 59 PKETPSSANGPSREGSRLPPA--------REGHPVYPQLRPGYIPIP------------- 97
PK+ P + P R+ RL P+ R P P + + P P
Sbjct: 371 PKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSV 430
Query: 98 ---------VLHEGAENRQVHPFHVYPQPGMQRFRTEAAA---------AAPQRSQSPLR 139
H+G E R+ P P + + E + AA Q +
Sbjct: 431 SPGRTSGKVTKHKGTEKRES------PSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQ 484
Query: 140 GMPETTQPDKQCGQVAAAAAAQPPASH------------GPERSQSPAASDCSSSSS--- 184
+ Q G +++ +P SH P RS SP+ +S
Sbjct: 485 YRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRG 544
Query: 185 ----SASLPSSGRSSLGSHQLPRGYISIPVIHEQNVTRPAAQPSFHQAQKTHY-PAQQGE 239
S S P + R S P P + T P+ P Y P Q
Sbjct: 545 RRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRT-PSPPPRRRSPSPRRYSPPIQRR 603
Query: 240 YQTHQPVYHKIQGDDWEPRPLRAASPF-----------------------RSSVQGASSR 276
Y P + P P R ASP RS + R
Sbjct: 604 YSPSPPPKRRTASPP--PPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHR 661
Query: 277 EGS-PARSSTPLHSPSPIRVHTVVDRPQQPMTHRETAPVSQ-PENKPESKPGPVGPELPP 334
+GS P+RS+ SP P + H+ RP+ P T PV + + P+ + P P
Sbjct: 662 KGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSP-----SP 716
Query: 335 GHIPIQVIRKEVDSKPVSQKPPPPSEKVE----------VKVPPAPVPCPPPSPGPSAVP 384
PI+ + + + K + + P + V P A P PPSP S P
Sbjct: 717 STRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSP 776
Query: 385 SSPKSVATEERAAPSTAPAEATPPKPGEAEAPPK 418
S+ S A + A S P+ +PP+ + E K
Sbjct: 777 STNWSPAVPVKKAKSPTPS-PSPPRNSDQEGGGK 809
Score = 56.6 bits (135), Expect = 6e-08
Identities = 98/435 (22%), Positives = 153/435 (35%), Gaps = 82/435 (18%)
Query: 44 SRTTTWNDPRVPSEGPKETPSSANGPSREGSRLPPAREGHPVYPQLRPGYIPIPVLHEGA 103
SR+ + + R S P T SR S P R P+ RP +
Sbjct: 278 SRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPS----PRRRP-----------S 322
Query: 104 ENRQVHPFHVYPQPGMQRFRT--------------EAAAAAPQRSQSPLRGMPE-TTQPD 148
R+ P + P P +R R+ +++++ RS+SP + P+ T+ P
Sbjct: 323 PRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPP 382
Query: 149 KQCGQVAAAAAA-------QPPASHGPERSQSPAASDCSSSSSSASLPSSGRSSLGSHQL 201
++ +++ +A+ PPA+ P+ SP + + S S GR+S G
Sbjct: 383 RKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTS-GKVTK 441
Query: 202 PRGYISIPVIHEQNVTRPAAQP-----SFHQAQKTHYPAQQGEYQTHQPVYHKIQ---GD 253
+G ++ PA +P S + K A Q + + Q D
Sbjct: 442 HKG------TEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSD 495
Query: 254 DWEPRPLRAASPFRSSVQGAS---SREGSPARSSTPLHSPSPIRVHTVVD-----RPQQP 305
P RS V+ R SP+RS++P SP + T P P
Sbjct: 496 SGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASP--SPRKRQKETSPRGRRRRSPSPP 553
Query: 306 MTHRETAPVSQPENKPESKPGPVGPELPPGHIPIQVIRKEVDSKPVSQK---PPPPSEKV 362
T R +P P + P P P P + P Q+ P PP ++
Sbjct: 554 PTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRR 613
Query: 363 EVKVPPAPVPCPPPSPGP------SAVPSSPKSVATEER-----------AAPSTAPAEA 405
PP P PSP P S P S T+ R ++PS + EA
Sbjct: 614 TASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREA 673
Query: 406 TPPKPGEAEAPPKHP 420
P+P + +P P
Sbjct: 674 RSPQPNKRHSPSPRP 688
Score = 37.0 bits (84), Expect = 0.049
Identities = 43/159 (27%), Positives = 62/159 (38%), Gaps = 30/159 (18%)
Query: 44 SRTTTWNDPRVPSEGPKETPSSANGPSREGSRLPPAREGHPVYPQLRPGYIPIPVLHEGA 103
SR+T + R P + +PS + S PP R G PQ R P
Sbjct: 667 SRST--REARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSP-------- 716
Query: 104 ENRQVHPFHVYPQPGMQRFRTEAAAAAPQ--RSQSPLRGMPETTQPDKQCGQVAAAAAAQ 161
R + P+P + +AA+ +PQ R S R + + +P AA +
Sbjct: 717 STRPIRRVSRTPEPKKIK---KAASPSPQSVRRVSSSRSVSGSPEP----------AAKK 763
Query: 162 PPASHGPERSQSPA-----ASDCSSSSSSASLPSSGRSS 195
PPA P +SQSP+ A + S PS R+S
Sbjct: 764 PPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNS 802
Score = 33.5 bits (75), Expect = 0.54
Identities = 35/162 (21%), Positives = 61/162 (37%), Gaps = 24/162 (14%)
Query: 249 KIQGDDWEPRPLRAASPFRSSVQGASSREGSPARSSTPLHSPSPIRVHTVVDRPQQPMTH 308
K Q +D + R R + + S +RS +P SP+R + P
Sbjct: 145 KKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHR 204
Query: 309 RET-APVSQPENKPESKPGPVGPELPPGHIPIQVIRKEVDSKPVSQKPPPPSEKVEVKVP 367
++ +P PE K ++ PELP + ++ +P Q+ S+ ++V
Sbjct: 205 TKSRSPSPAPEKKEKT------PELPEPSVKVK--------EPSVQEATSTSDILKV--- 247
Query: 368 PAPVPCPPPSPGPSAVPSSPKSVATEERAAPSTAPAEATPPK 409
P P P P SP+ + +E+ T P + K
Sbjct: 248 ------PKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSK 283
>gi|33286436 gametogenetin [Homo sapiens]
Length = 652
Score = 57.8 bits (138), Expect = 3e-08
Identities = 99/417 (23%), Positives = 138/417 (33%), Gaps = 91/417 (21%)
Query: 70 SREGSRLPPAREGHPVYPQLRPGYIPIPVLHEGAENRQVHPFHVY-PQPGMQRFRTEAAA 128
S G PP+ P+ P P + + A ++ P + P P + R A
Sbjct: 129 SHRGQGDPPSLR--PLKPPPPPRQLSVKDTVPRAPSQFPPPLETWKPPPPLPSERQPADR 186
Query: 129 AAPQRSQSPLRGMPETTQPDKQCGQVAAAAAAQPPASHGPERSQSPAASDC--------- 179
+P E+ + GQ A A P G PA S+
Sbjct: 187 RITPALATPASPPTESQAGPRNQGQTAGRARGGAPPHAGEGEMAQPADSESGLSLLCKIT 246
Query: 180 ----------SSSSSSASLPSSGRSSLGSHQLPRGYISIPVIHEQNVTRPAAQPSFHQAQ 229
++SSS A+ S G G G IS + +Q P A +
Sbjct: 247 FKSRPSLAPPAASSSLAAKASLGGGGGGGLFAASGAISYAEVLKQGPLPPGAARPLGEVS 306
Query: 230 KTHYPAQQGEYQTH-----------------QPVYHKIQGD----DWEPRPLRAASPFRS 268
+ A+ G+ P Y G DW P FR
Sbjct: 307 RGAQEAEGGDGDGEGCSGPPSAPASQARALPPPPYTTFPGSKPKFDWVSAPDGPERHFRF 366
Query: 269 SVQGASSREGSPARSSTPLHSP------SPIRVHTVVD--RPQQPMTHRETAPVSQPENK 320
+ GA G+P R + L P P ++H+ RP + T P N
Sbjct: 367 N--GAGGGIGAPRRRAAALSGPWGSPPPPPEQIHSAPGPRRPAPALLAPPTFIFPAPTNG 424
Query: 321 PESKPGPVG-PELPPGHIPIQVIRKEVDSKPVSQKPPPPSEKVEVKVPPAPVP-----CP 374
+PGP G ELPP +P PP P ++ PPA P P
Sbjct: 425 EPMRPGPPGLQELPP--LP----------------PPTPPPTLQ---PPALQPTPLPVAP 463
Query: 375 PPSPG---------PSAVPSSPKSVATEERAAPSTAPAE--ATPPKPGEAEAPPKHP 420
P +PG P+A P+ P ++A ++ APS APA A P P A AP P
Sbjct: 464 PLTPGLGHKESALAPTAAPALPPALAADQAPAPSPAPAPTVAEPSPPVSAPAPAAAP 520
Score = 50.1 bits (118), Expect = 6e-06
Identities = 47/146 (32%), Positives = 63/146 (43%), Gaps = 19/146 (13%)
Query: 291 SPIRVHTVVDRPQQPMTH-RETAPVSQPENKPESK--PGPVGPELPPGHIPIQVIRKEVD 347
SP + ++RP M E A VS P P PGP + P G P+ IR+ ++
Sbjct: 69 SPSTLPLTLERPSPVMPPPEEAAAVSAPPPAPAGTLLPGPSKWQKPAG-TPVPRIRRLLE 127
Query: 348 SKPVSQ---------KPPPPSEKVEVK--VPPAPVPCPPPSPGPSAVPSSPKSVATEERA 396
+ Q KPPPP ++ VK VP AP PPP P P +R
Sbjct: 128 ASHRGQGDPPSLRPLKPPPPPRQLSVKDTVPRAPSQFPPPLETWKPPPPLPSERQPADR- 186
Query: 397 APSTAPAEATPPK-PGEAEAPPKHPG 421
PA ATP P E++A P++ G
Sbjct: 187 --RITPALATPASPPTESQAGPRNQG 210
>gi|18079216 CASK interacting protein 1 [Homo sapiens]
Length = 1431
Score = 57.4 bits (137), Expect = 4e-08
Identities = 63/234 (26%), Positives = 85/234 (36%), Gaps = 27/234 (11%)
Query: 277 EGSPARSSTPLHSPSPIRVHTVVDRPQQPMTHRETAPVSQPENKPESKPGPVGPELPPGH 336
EG + + P SP P+ QP+ + +P P +K PGP PE+ H
Sbjct: 1215 EGEARKPAKPPVSPKPVLT--------QPVPKLQGSPT--PTSKKVPLPGPGSPEVKRAH 1264
Query: 337 IPIQVIRKEVDSKPVSQKPPPP--SEKVEVKVPPAPVPCPPPSPGPSAVPSSPKSVATEE 394
PVS KPPPP + K V P PSP PS P ++A
Sbjct: 1265 ---------GTPPPVSPKPPPPPTAPKPVKAVAGLPSGSAGPSPAPSPARQPPAALAKPP 1315
Query: 395 RAAPSTAPAEATPPKPGEAEAPPKHPGVLKVEAILEKVQGLEQAVDNFEGKKT-DKKYLM 453
PS + A PP PG AP H A EG D
Sbjct: 1316 GTPPSLGASPAKPPSPG---APALHVPAKPPRAAAAAAAAAAAPPAPPEGASPGDSARQK 1372
Query: 454 IEEYLTKELLALDSVDPEGRADVRQARRDGVRKVQT--ILEKLEQKAIDVPGQV 505
+EE AL +V+ + R + Q RD + T IL+ + D+ Q+
Sbjct: 1373 LEETSACLAAALQAVEEKIRQEDAQGPRDSAAEKSTGSILDDIGSMFDDLADQL 1426
Score = 41.6 bits (96), Expect = 0.002
Identities = 36/123 (29%), Positives = 52/123 (42%), Gaps = 24/123 (19%)
Query: 318 ENKPESKPGPVGPELPPGHIPIQVIRK---EVDSKPVSQK--------PPPPSEKVEVKV 366
+ +P++K GPE PP P+ V V +P S++ PPPP+E +
Sbjct: 1149 KRRPKAKEREAGPEPPP---PLSVYHNGTGTVRRRPASEQAGPPELPPPPPPAEPPPTDL 1205
Query: 367 PPAPVPCPPP---SPGPSAVPSSPKSVATEERAAPSTAPAEATPPKPGEAEAPPKHPGVL 423
P P PPP + P+ P SPK V T+ P P P + P PG
Sbjct: 1206 AHLP-PLPPPEGEARKPAKPPVSPKPVLTQP------VPKLQGSPTPTSKKVPLPGPGSP 1258
Query: 424 KVE 426
+V+
Sbjct: 1259 EVK 1261
Score = 40.4 bits (93), Expect = 0.004
Identities = 52/200 (26%), Positives = 66/200 (33%), Gaps = 24/200 (12%)
Query: 23 PPGWEIKIDPQTGWPFFVDHNSRTTTWNDPRVPSEGPKE---TPSSANGPSREGSRLP-- 77
P E + P+ P V HN T P GP E P A P + + LP
Sbjct: 1152 PKAKEREAGPEPPPPLSVYHNGTGTVRRRPASEQAGPPELPPPPPPAEPPPTDLAHLPPL 1211
Query: 78 PAREGHPVYPQLRPGYIPIPVLHEGAENRQVHPFHV-----YPQPGMQRFRTEAAAAAPQ 132
P EG P +P P PVL + Q P P PG + P
Sbjct: 1212 PPPEGEARKP-AKPPVSPKPVLTQPVPKLQGSPTPTSKKVPLPGPGSPEVKRAHGTPPPV 1270
Query: 133 RSQSPLRGMPETTQPDKQCGQVAAAAAAQPPASHGPERSQSPAASDCSSSSSSASLPSSG 192
+ P P T P + A A P S GP SPA S ++ + P
Sbjct: 1271 SPKPP----PPPTAP-----KPVKAVAGLPSGSAGP----SPAPSPARQPPAALAKPPGT 1317
Query: 193 RSSLGSHQLPRGYISIPVIH 212
SLG+ P +H
Sbjct: 1318 PPSLGASPAKPPSPGAPALH 1337
Score = 40.0 bits (92), Expect = 0.006
Identities = 58/234 (24%), Positives = 80/234 (34%), Gaps = 55/234 (23%)
Query: 237 QGEYQTHQPVYHKIQGDDWEPRPLRAASPFRSSVQ-------GASSREGSPARSSTPLHS 289
+GE P K++ R +RA + +V+ R + R + P
Sbjct: 1105 KGEAGVEGPPLAKVEASATLKRRIRAKQNQQENVKFILTESDTVKRRPKAKEREAGP-EP 1163
Query: 290 PSPIRVH-----TVVDRPQQPMTHRETAPVSQPENKPESKPGPVG-PELPPGHIPIQVIR 343
P P+ V+ TV RP + P P P ++P P LPP P R
Sbjct: 1164 PPPLSVYHNGTGTVRRRPAS----EQAGPPELPPPPPPAEPPPTDLAHLPPLPPPEGEAR 1219
Query: 344 KEVDSKPVSQKPPPPSEKVEVKVPPAPVPCPPPSPGPSA-------------------VP 384
K PVS KP +++ P P P PGP + P
Sbjct: 1220 KPA-KPPVSPKPVLTQPVPKLQGSPTPTSKKVPLPGPGSPEVKRAHGTPPPVSPKPPPPP 1278
Query: 385 SSPKSVAT-----EERAAPSTAPAEA------------TPPKPGEAEAPPKHPG 421
++PK V A PS AP+ A TPP G + A P PG
Sbjct: 1279 TAPKPVKAVAGLPSGSAGPSPAPSPARQPPAALAKPPGTPPSLGASPAKPPSPG 1332
Score = 36.2 bits (82), Expect = 0.084
Identities = 41/154 (26%), Positives = 55/154 (35%), Gaps = 22/154 (14%)
Query: 277 EGSPARSSTP-------LHSPSPIRVHTVVDRPQQPMTHRETAPVSQPENKPESKPGPVG 329
EG P R P + SP P T D MT + + +S + P VG
Sbjct: 614 EGGPLRRKAPQSLEVMAIESPPPPEP-TPADCQSPKMTTFQDSELSDELQAAMTGPAEVG 672
Query: 330 P--ELPPGHIPIQVIRKEVDSKPVSQKPPPPSEKVEVKVPPAPVPCPPPSPGPSAVPSSP 387
P E P H+P + + S E+ + P PGPS+ S
Sbjct: 673 PTTEKPSSHLPPTPRATTRQDSSLGGRARHMSSSQEL-LGDGP-------PGPSSPMSRS 724
Query: 388 KSVATEERAAPSTAPAEATPPKPG----EAEAPP 417
+ +E AP T P EA P + G A PP
Sbjct: 725 QEYLLDEGPAPGTPPREARPGRHGHSIKRASVPP 758
Score = 36.2 bits (82), Expect = 0.084
Identities = 64/274 (23%), Positives = 93/274 (33%), Gaps = 47/274 (17%)
Query: 157 AAAAQPPASHGPERSQSPAASDCSSSSSSASLPSSGRSSLGSHQLPRGYISIPVIHEQNV 216
A + PP P QSP + S S L ++ ++ P
Sbjct: 630 AIESPPPPEPTPADCQSPKMTTFQDSELSDELQAA--------------MTGPAEVGPTT 675
Query: 217 TRPAAQPSFHQAQKTHYPAQQGEYQTHQPVYHKIQGDDWEPRPLRAASPFRSSVQGASSR 276
+P++ T + G H ++ GD P P S + +
Sbjct: 676 EKPSSHLPPTPRATTRQDSSLGGRARHMSSSQELLGDG-PPGPSSPMSRSQEYLLDEGPA 734
Query: 277 EGSPARSSTPL---HSPSPIRVHTVVDRPQQ---PMTHRETAPVSQPENKPESKP---GP 327
G+P R + P HS V V +P+Q P T T P + + +P S GP
Sbjct: 735 PGTPPREARPGRHGHSIKRASVPPVPGKPRQVLPPGTSHFTPPQTPTKTRPGSPQALGGP 794
Query: 328 VGPELPPGHIPIQVIRKEVDSKPVSQKPPPPS-----------EKVEVKV-PPAPVPCPP 375
GP + +P+S + P S + VE +V P AP P PP
Sbjct: 795 HGPAPATAKVKPTPQLLPPTERPMSPRSLPQSPTHRGFAYVLPQPVEGEVGPAAPGPAPP 854
Query: 376 PSPGPSAVPSSPKSVATEERAAPSTAPAEATPPK 409
P P+AVP+ P A AE PK
Sbjct: 855 PV--PTAVPT---------LCLPPEADAEPGRPK 877
Score = 33.5 bits (75), Expect = 0.54
Identities = 26/92 (28%), Positives = 35/92 (38%), Gaps = 9/92 (9%)
Query: 325 PGPVGPELPPGHIPIQVIRKEVDSKPVSQKPPPPSEKVEVKVPPAPVPCPPPSPGPSAVP 384
PG E PG + R V PP P + +V +PP PP P
Sbjct: 735 PGTPPREARPGRHGHSIKRASV--------PPVPGKPRQV-LPPGTSHFTPPQTPTKTRP 785
Query: 385 SSPKSVATEERAAPSTAPAEATPPKPGEAEAP 416
SP+++ AP+TA + TP E P
Sbjct: 786 GSPQALGGPHGPAPATAKVKPTPQLLPPTERP 817
>gi|222352183 neural precursor cell expressed, developmentally
down-regulated 4-like isoform 2 [Homo sapiens]
Length = 854
Score = 57.4 bits (137), Expect = 4e-08
Identities = 30/60 (50%), Positives = 39/60 (65%), Gaps = 3/60 (5%)
Query: 22 LPPGWEIKIDPQTGWPFFVDHNSRTTTWNDPRVPSEGPKETPSSANGPSREGSRLPPARE 81
LPPGWE++I P G PFF+DHN++TTTW DPR+ + +S N P+ G LPP E
Sbjct: 378 LPPGWEMRIAPN-GRPFFIDHNTKTTTWEDPRLKFPVHMRSKTSLN-PNDLGP-LPPGWE 434
Score = 48.5 bits (114), Expect = 2e-05
Identities = 27/73 (36%), Positives = 35/73 (47%), Gaps = 13/73 (17%)
Query: 18 DRDPLPPGWEIKIDPQTGWPFFVDHNSRTTTWNDPRVPSEGPKETPSSANGPSREGSRLP 77
D PLPPGWE +I G F++DHNS+ T W DPR+ P+ G +P
Sbjct: 425 DLGPLPPGWEERIHLD-GRTFYIDHNSKITQWEDPRL------------QNPAITGPAVP 471
Query: 78 PAREGHPVYPQLR 90
+RE Y R
Sbjct: 472 YSREFKQKYDYFR 484
Score = 44.7 bits (104), Expect = 2e-04
Identities = 18/32 (56%), Positives = 24/32 (75%), Gaps = 1/32 (3%)
Query: 21 PLPPGWEIKIDPQTGWPFFVDHNSRTTTWNDP 52
PLPPGWE K+D G ++V+HN+RTT W+ P
Sbjct: 73 PLPPGWEEKVD-NLGRTYYVNHNNRTTQWHRP 103
Score = 38.5 bits (88), Expect = 0.017
Identities = 18/48 (37%), Positives = 31/48 (64%), Gaps = 3/48 (6%)
Query: 22 LPPGWEIKIDPQTGWPFFVDHNSRTTTWNDP--RVPSEGPKETPSSAN 67
LP GWE + D + G ++V+HN+RTTTW P ++ +G + +++N
Sbjct: 266 LPSGWEERKDAK-GRTYYVNHNNRTTTWTRPIMQLAEDGASGSATNSN 312
>gi|21361472 neural precursor cell expressed, developmentally
down-regulated 4-like isoform 3 [Homo sapiens]
Length = 955
Score = 57.4 bits (137), Expect = 4e-08
Identities = 30/60 (50%), Positives = 39/60 (65%), Gaps = 3/60 (5%)
Query: 22 LPPGWEIKIDPQTGWPFFVDHNSRTTTWNDPRVPSEGPKETPSSANGPSREGSRLPPARE 81
LPPGWE++I P G PFF+DHN++TTTW DPR+ + +S N P+ G LPP E
Sbjct: 479 LPPGWEMRIAPN-GRPFFIDHNTKTTTWEDPRLKFPVHMRSKTSLN-PNDLGP-LPPGWE 535
Score = 48.5 bits (114), Expect = 2e-05
Identities = 27/73 (36%), Positives = 35/73 (47%), Gaps = 13/73 (17%)
Query: 18 DRDPLPPGWEIKIDPQTGWPFFVDHNSRTTTWNDPRVPSEGPKETPSSANGPSREGSRLP 77
D PLPPGWE +I G F++DHNS+ T W DPR+ P+ G +P
Sbjct: 526 DLGPLPPGWEERIHLD-GRTFYIDHNSKITQWEDPRL------------QNPAITGPAVP 572
Query: 78 PAREGHPVYPQLR 90
+RE Y R
Sbjct: 573 YSREFKQKYDYFR 585
Score = 44.7 bits (104), Expect = 2e-04
Identities = 18/32 (56%), Positives = 24/32 (75%), Gaps = 1/32 (3%)
Query: 21 PLPPGWEIKIDPQTGWPFFVDHNSRTTTWNDP 52
PLPPGWE K+D G ++V+HN+RTT W+ P
Sbjct: 194 PLPPGWEEKVD-NLGRTYYVNHNNRTTQWHRP 224
Score = 38.5 bits (88), Expect = 0.017
Identities = 18/48 (37%), Positives = 31/48 (64%), Gaps = 3/48 (6%)
Query: 22 LPPGWEIKIDPQTGWPFFVDHNSRTTTWNDP--RVPSEGPKETPSSAN 67
LP GWE + D + G ++V+HN+RTTTW P ++ +G + +++N
Sbjct: 367 LPSGWEERKDAK-GRTYYVNHNNRTTTWTRPIMQLAEDGASGSATNSN 413
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.127 0.376
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,676,563
Number of Sequences: 37866
Number of extensions: 2059831
Number of successful extensions: 36201
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 613
Number of HSP's successfully gapped in prelim test: 1676
Number of HSP's that attempted gapping in prelim test: 14358
Number of HSP's gapped (non-prelim): 12048
length of query: 575
length of database: 18,247,518
effective HSP length: 108
effective length of query: 467
effective length of database: 14,157,990
effective search space: 6611781330
effective search space used: 6611781330
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.