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Search of human proteins with 14042939
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|14042939 chromosome 10 open reading frame 11 [Homo sapiens]
(198 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|14042939 chromosome 10 open reading frame 11 [Homo sapiens] 395 e-111
gi|50593002 small nuclear ribonucleoprotein polypeptide A' [Homo... 57 8e-09
gi|239754500 PREDICTED: Leucine-rich repeat-containing protein E... 54 7e-08
gi|239749060 PREDICTED: Leucine-rich repeat-containing protein E... 54 7e-08
gi|239743086 PREDICTED: Leucine-rich repeat-containing protein E... 54 7e-08
gi|239508737 PREDICTED: Leucine-rich repeat-containing protein E... 54 7e-08
gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 famil... 48 6e-06
gi|194272228 leucine rich repeat containing 48 isoform b [Homo s... 45 4e-05
gi|194272226 leucine rich repeat containing 48 isoform b [Homo s... 45 4e-05
gi|194272224 leucine rich repeat containing 48 isoform a [Homo s... 45 4e-05
gi|194272222 leucine rich repeat containing 48 isoform a [Homo s... 45 4e-05
gi|31621309 leucine rich repeat containing 6 [Homo sapiens] 45 4e-05
gi|4826651 hypothetical protein LOC755 [Homo sapiens] 43 2e-04
gi|87298937 centrosomal protein 110kDa [Homo sapiens] 43 2e-04
gi|21389483 leucine-rich repeats and guanylate kinase domain con... 41 8e-04
gi|120953300 leucine-rich repeats and IQ motif containing 1 isof... 40 0.001
gi|120953243 leucine-rich repeats and IQ motif containing 1 isof... 40 0.001
gi|15529980 leucine rich repeat containing 46 [Homo sapiens] 39 0.002
gi|53828918 Rab geranylgeranyltransferase alpha [Homo sapiens] 39 0.003
gi|33469951 Rab geranylgeranyltransferase alpha [Homo sapiens] 39 0.003
gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 fami... 38 0.006
gi|116268109 nucleotide-binding oligomerization domains 27 [Homo... 38 0.006
gi|194239701 tubulin folding cofactor E-like [Homo sapiens] 37 0.008
gi|194239699 tubulin folding cofactor E-like [Homo sapiens] 37 0.008
gi|117414162 sodium channel associated protein 2 isoform a [Homo... 37 0.011
gi|55743114 leucine rich repeat containing 49 [Homo sapiens] 37 0.011
gi|206725447 leucine rich repeat containing 23 isoform a [Homo s... 36 0.024
gi|42542396 leucine rich repeat containing 23 isoform a [Homo sa... 36 0.024
gi|62912474 leucine-rich repeat-containing G protein-coupled rec... 35 0.042
gi|239752518 PREDICTED: similar to leucine rich repeat containin... 35 0.054
>gi|14042939 chromosome 10 open reading frame 11 [Homo sapiens]
Length = 198
Score = 395 bits (1016), Expect = e-111
Identities = 198/198 (100%), Positives = 198/198 (100%)
Query: 1 MEKYLSLSGNHSSNKRSLEGLSAFRSLEELILDNNQLGDDLVLPGLPRLHTLTLNKNRIT 60
MEKYLSLSGNHSSNKRSLEGLSAFRSLEELILDNNQLGDDLVLPGLPRLHTLTLNKNRIT
Sbjct: 1 MEKYLSLSGNHSSNKRSLEGLSAFRSLEELILDNNQLGDDLVLPGLPRLHTLTLNKNRIT 60
Query: 61 DLENLLDHLAEVTPALEYLSLLGNVACPNELVSLEKDEEDYKRYRCFVLYKLPNLKFLDA 120
DLENLLDHLAEVTPALEYLSLLGNVACPNELVSLEKDEEDYKRYRCFVLYKLPNLKFLDA
Sbjct: 61 DLENLLDHLAEVTPALEYLSLLGNVACPNELVSLEKDEEDYKRYRCFVLYKLPNLKFLDA 120
Query: 121 QKVTRQEREEALVRGVFMKVVKPKASSEDVASSPERHYTPLPSASRELTSHQGVLGKCRY 180
QKVTRQEREEALVRGVFMKVVKPKASSEDVASSPERHYTPLPSASRELTSHQGVLGKCRY
Sbjct: 121 QKVTRQEREEALVRGVFMKVVKPKASSEDVASSPERHYTPLPSASRELTSHQGVLGKCRY 180
Query: 181 VYYGKNSEGNRFIRDDQL 198
VYYGKNSEGNRFIRDDQL
Sbjct: 181 VYYGKNSEGNRFIRDDQL 198
>gi|50593002 small nuclear ribonucleoprotein polypeptide A' [Homo
sapiens]
Length = 255
Score = 57.4 bits (137), Expect = 8e-09
Identities = 43/119 (36%), Positives = 65/119 (54%), Gaps = 18/119 (15%)
Query: 16 RSLEGLSAFRSLEELILDNNQL---GDDLVLPGLPRLHTLTLNKNRITDLENLLDHLAEV 72
R L+G R L+ L+++NN++ G+ L LP L L L N + +L +L D LA +
Sbjct: 55 RKLDGFPLLRRLKTLLVNNNRICRIGEGLD-QALPCLTELILTNNSLVELGDL-DPLASL 112
Query: 73 TPALEYLSLLGNVACPNELVSLEKDEEDYKRYRCFVLYKLPNLKFLDAQKVTRQEREEA 131
+L YLS+L N + K YR +V+YK+P ++ LD QKV +ER+EA
Sbjct: 113 K-SLTYLSILRNPVT------------NKKHYRLYVIYKVPQVRVLDFQKVKLKERQEA 158
>gi|239754500 PREDICTED: Leucine-rich repeat-containing protein
ENSP00000371558 [Homo sapiens]
Length = 336
Score = 54.3 bits (129), Expect = 7e-08
Identities = 40/130 (30%), Positives = 62/130 (47%), Gaps = 16/130 (12%)
Query: 3 KYLSLSGNHSSNKRSLEGLSAFRSLEELILDNNQLGDDLVLPGLPRLHTLTLNKNRITDL 62
KYL L H + + L+ L EL L+NN + + L LP LH L L+ N +T++
Sbjct: 119 KYLWL---HHNKLHGITFLTRNYCLTELYLNNNAIFEIEGLHYLPSLHILLLHHNELTNI 175
Query: 63 ENLLDHLAEVTPALEYLSLLGNVACPNELVSLEKDEEDYKRYRCFVLYKLPNLKFLDAQK 122
+ + L + L+ LSL N C Y YR +++Y LP ++ LD +
Sbjct: 176 DATVKELKGMLN-LKILSLYQNPLC------------QYNLYRLYIIYHLPGVELLDRNQ 222
Query: 123 VTRQEREEAL 132
VT +ER +
Sbjct: 223 VTEKERRSMI 232
>gi|239749060 PREDICTED: Leucine-rich repeat-containing protein
ENSP00000371558 [Homo sapiens]
Length = 336
Score = 54.3 bits (129), Expect = 7e-08
Identities = 40/130 (30%), Positives = 62/130 (47%), Gaps = 16/130 (12%)
Query: 3 KYLSLSGNHSSNKRSLEGLSAFRSLEELILDNNQLGDDLVLPGLPRLHTLTLNKNRITDL 62
KYL L H + + L+ L EL L+NN + + L LP LH L L+ N +T++
Sbjct: 119 KYLWL---HHNKLHGITFLTRNYCLTELYLNNNAIFEIEGLHYLPSLHILLLHHNELTNI 175
Query: 63 ENLLDHLAEVTPALEYLSLLGNVACPNELVSLEKDEEDYKRYRCFVLYKLPNLKFLDAQK 122
+ + L + L+ LSL N C Y YR +++Y LP ++ LD +
Sbjct: 176 DATVKELKGMLN-LKILSLYQNPLC------------QYNLYRLYIIYHLPGVELLDRNQ 222
Query: 123 VTRQEREEAL 132
VT +ER +
Sbjct: 223 VTEKERRSMI 232
>gi|239743086 PREDICTED: Leucine-rich repeat-containing protein
ENSP00000371558 [Homo sapiens]
Length = 336
Score = 54.3 bits (129), Expect = 7e-08
Identities = 40/130 (30%), Positives = 62/130 (47%), Gaps = 16/130 (12%)
Query: 3 KYLSLSGNHSSNKRSLEGLSAFRSLEELILDNNQLGDDLVLPGLPRLHTLTLNKNRITDL 62
KYL L H + + L+ L EL L+NN + + L LP LH L L+ N +T++
Sbjct: 119 KYLWL---HHNKLHGITFLTRNYCLTELYLNNNAIFEIEGLHYLPSLHILLLHHNELTNI 175
Query: 63 ENLLDHLAEVTPALEYLSLLGNVACPNELVSLEKDEEDYKRYRCFVLYKLPNLKFLDAQK 122
+ + L + L+ LSL N C Y YR +++Y LP ++ LD +
Sbjct: 176 DATVKELKGMLN-LKILSLYQNPLC------------QYNLYRLYIIYHLPGVELLDRNQ 222
Query: 123 VTRQEREEAL 132
VT +ER +
Sbjct: 223 VTEKERRSMI 232
>gi|239508737 PREDICTED: Leucine-rich repeat-containing protein
ENSP00000371558 [Homo sapiens]
Length = 336
Score = 54.3 bits (129), Expect = 7e-08
Identities = 40/130 (30%), Positives = 62/130 (47%), Gaps = 16/130 (12%)
Query: 3 KYLSLSGNHSSNKRSLEGLSAFRSLEELILDNNQLGDDLVLPGLPRLHTLTLNKNRITDL 62
KYL L H + + L+ L EL L+NN + + L LP LH L L+ N +T++
Sbjct: 119 KYLWL---HHNKLHGITFLTRNYCLTELYLNNNAIFEIEGLHYLPSLHILLLHHNELTNI 175
Query: 63 ENLLDHLAEVTPALEYLSLLGNVACPNELVSLEKDEEDYKRYRCFVLYKLPNLKFLDAQK 122
+ + L + L+ LSL N C Y YR +++Y LP ++ LD +
Sbjct: 176 DATVKELKGMLN-LKILSLYQNPLC------------QYNLYRLYIIYHLPGVELLDRNQ 222
Query: 123 VTRQEREEAL 132
VT +ER +
Sbjct: 223 VTEKERRSMI 232
>gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 family,
member B [Homo sapiens]
Length = 251
Score = 47.8 bits (112), Expect = 6e-06
Identities = 47/136 (34%), Positives = 61/136 (44%), Gaps = 17/136 (12%)
Query: 10 NHSSNKRSLEGLSA-FRSLEELILDNNQLGDDLVLPGLPRLHTLTLNKNRITDLENLLDH 68
N SN +EGL+A F +LE L L N L LP LP+L L L++NRI LD
Sbjct: 26 NCKSNDGKIEGLTAEFVNLEFLSLINVGLISVSNLPKLPKLKKLELSENRIF---GGLDM 82
Query: 69 LAEVTPALEYLSLLGN-------------VACPNELVSLEKDEEDYKRYRCFVLYKLPNL 115
LAE P L +L+L GN + C L + + YR V LP L
Sbjct: 83 LAEKLPNLTHLNLSGNKLKDISTLEPLKKLECLKSLDLFNCEVTNLNDYRESVFKLLPQL 142
Query: 116 KFLDAQKVTRQEREEA 131
+LD QE ++
Sbjct: 143 TYLDGYDREDQEAPDS 158
>gi|194272228 leucine rich repeat containing 48 isoform b [Homo
sapiens]
Length = 457
Score = 45.1 bits (105), Expect = 4e-05
Identities = 38/120 (31%), Positives = 58/120 (48%), Gaps = 17/120 (14%)
Query: 4 YLSLSGNHSSNKRSLEGLSAFRSLEELILDNNQLGDDLVLPGLPRLHTLTLNKNRITDLE 63
+L LS N N ++EGL +LE+L L NN++ L L +L L+L NRI ++
Sbjct: 91 WLDLSFN---NIETIEGLDTLVNLEDLSLFNNRISKIDSLDALVKLQVLSLGNNRIDNMM 147
Query: 64 NLLDHLAEVTPALEYLSLLGNVACPNELVSLEKDEEDYKRYRCFVLYKLPNLKFLDAQKV 123
N++ L LSL N + EDYK + C LP+L +LD +++
Sbjct: 148 NII--YLRRFKCLRTLSLSRNPI---------SEAEDYKMFICAY---LPDLMYLDYRRI 193
>gi|194272226 leucine rich repeat containing 48 isoform b [Homo
sapiens]
Length = 457
Score = 45.1 bits (105), Expect = 4e-05
Identities = 38/120 (31%), Positives = 58/120 (48%), Gaps = 17/120 (14%)
Query: 4 YLSLSGNHSSNKRSLEGLSAFRSLEELILDNNQLGDDLVLPGLPRLHTLTLNKNRITDLE 63
+L LS N N ++EGL +LE+L L NN++ L L +L L+L NRI ++
Sbjct: 91 WLDLSFN---NIETIEGLDTLVNLEDLSLFNNRISKIDSLDALVKLQVLSLGNNRIDNMM 147
Query: 64 NLLDHLAEVTPALEYLSLLGNVACPNELVSLEKDEEDYKRYRCFVLYKLPNLKFLDAQKV 123
N++ L LSL N + EDYK + C LP+L +LD +++
Sbjct: 148 NII--YLRRFKCLRTLSLSRNPI---------SEAEDYKMFICAY---LPDLMYLDYRRI 193
>gi|194272224 leucine rich repeat containing 48 isoform a [Homo
sapiens]
Length = 523
Score = 45.1 bits (105), Expect = 4e-05
Identities = 38/120 (31%), Positives = 58/120 (48%), Gaps = 17/120 (14%)
Query: 4 YLSLSGNHSSNKRSLEGLSAFRSLEELILDNNQLGDDLVLPGLPRLHTLTLNKNRITDLE 63
+L LS N N ++EGL +LE+L L NN++ L L +L L+L NRI ++
Sbjct: 91 WLDLSFN---NIETIEGLDTLVNLEDLSLFNNRISKIDSLDALVKLQVLSLGNNRIDNMM 147
Query: 64 NLLDHLAEVTPALEYLSLLGNVACPNELVSLEKDEEDYKRYRCFVLYKLPNLKFLDAQKV 123
N++ L LSL N + EDYK + C LP+L +LD +++
Sbjct: 148 NII--YLRRFKCLRTLSLSRNPI---------SEAEDYKMFICAY---LPDLMYLDYRRI 193
>gi|194272222 leucine rich repeat containing 48 isoform a [Homo
sapiens]
Length = 523
Score = 45.1 bits (105), Expect = 4e-05
Identities = 38/120 (31%), Positives = 58/120 (48%), Gaps = 17/120 (14%)
Query: 4 YLSLSGNHSSNKRSLEGLSAFRSLEELILDNNQLGDDLVLPGLPRLHTLTLNKNRITDLE 63
+L LS N N ++EGL +LE+L L NN++ L L +L L+L NRI ++
Sbjct: 91 WLDLSFN---NIETIEGLDTLVNLEDLSLFNNRISKIDSLDALVKLQVLSLGNNRIDNMM 147
Query: 64 NLLDHLAEVTPALEYLSLLGNVACPNELVSLEKDEEDYKRYRCFVLYKLPNLKFLDAQKV 123
N++ L LSL N + EDYK + C LP+L +LD +++
Sbjct: 148 NII--YLRRFKCLRTLSLSRNPI---------SEAEDYKMFICAY---LPDLMYLDYRRI 193
>gi|31621309 leucine rich repeat containing 6 [Homo sapiens]
Length = 466
Score = 45.1 bits (105), Expect = 4e-05
Identities = 38/131 (29%), Positives = 61/131 (46%), Gaps = 9/131 (6%)
Query: 11 HSSNKRSLEGLSAF-RSLEELILDNNQLGDDLVLPGLPRLHTLTLNKNRITDLENL--LD 67
H LE + + R L+ L L NN +G + L +L L L N I +ENL +
Sbjct: 29 HQQEIERLEHIDKWCRDLKILYLQNNLIGKIENVSKLKKLEYLNLALNNIEKIENLEGCE 88
Query: 68 HLAEVTPALEYLSLLGNVACPN------ELVSLEKDEEDYKRYRCFVLYKLPNLKFLDAQ 121
LA++ + ++ L ++ EL + + YR FV+ LP LK+LD +
Sbjct: 89 ELAKLDLTVNFIGELSSIKNLQHNIHLKELFLMGNPCASFDHYREFVVATLPQLKWLDGK 148
Query: 122 KVTRQEREEAL 132
++ ER +AL
Sbjct: 149 EIEPSERIKAL 159
>gi|4826651 hypothetical protein LOC755 [Homo sapiens]
Length = 256
Score = 43.1 bits (100), Expect = 2e-04
Identities = 42/134 (31%), Positives = 53/134 (39%), Gaps = 24/134 (17%)
Query: 26 SLEELILDNNQLGDDLVLPGLPRLHTLTLNKNRITDLENLLDHLAEVTPALEYLSLLGNV 85
SLE + L N + + RL L L +NRI L L + P L L L N
Sbjct: 41 SLEVITLSVNSISTLEPVSRCQRLSELYLRRNRIPSLAELF--YLKGLPRLRVLWLAENP 98
Query: 86 ACPNELVSLEKDEEDYKRYRCFVLYKLPNLKFLDAQKVTRQEREEALVRGVFMKVVKPKA 145
C RYR VL LP L+ LD Q VT +E AL G
Sbjct: 99 CCGTSP----------HRYRMTVLRTLPRLQKLDNQAVTEEELSRALSEG---------- 138
Query: 146 SSEDVASSPERHYT 159
E++ ++PER T
Sbjct: 139 --EEITAAPEREGT 150
>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
Length = 2325
Score = 43.1 bits (100), Expect = 2e-04
Identities = 42/138 (30%), Positives = 71/138 (51%), Gaps = 18/138 (13%)
Query: 1 MEKYLSLSG-NHSSNKRS-LEGLSAFRSLEELILDNNQLGDDLVLPG--LPRLHTLTLNK 56
++K L L N S NK S +EG+ +L++L L N++ V G L L L L
Sbjct: 143 LDKLLKLRELNLSYNKISKIEGIENMCNLQKLNLAGNEIEHIPVWLGKKLKSLRVLNLKG 202
Query: 57 NRITDLENLLDHLAEVTPALEYLSLLGNVACPNELVSLEKDEEDYKRYRCFVLYKLPNLK 116
N+I+ L+++ +++ P + +SL + N +V+L Y F ++ L +L+
Sbjct: 203 NKISSLQDI----SKLKPLQDLISL---ILVENPVVTLP-------HYLQFTIFHLRSLE 248
Query: 117 FLDAQKVTRQEREEALVR 134
L+ Q VT Q+R+EA R
Sbjct: 249 SLEGQPVTTQDRQEAFER 266
>gi|21389483 leucine-rich repeats and guanylate kinase domain
containing [Homo sapiens]
Length = 825
Score = 40.8 bits (94), Expect = 8e-04
Identities = 39/137 (28%), Positives = 62/137 (45%), Gaps = 12/137 (8%)
Query: 4 YLSLSGNHSSNKRSLEGLSAFRSLEELILDNNQLGDDLVLPGLPRLHTLTLNKNRITDLE 63
+LSL+ N + L L ++ L L NNQ+ L L L L L+ N+I+ L+
Sbjct: 241 HLSLANNKITTINGLNKLP----IKILCLSNNQIEMITGLEDLKALQNLDLSHNQISSLQ 296
Query: 64 NLLDH-LAEV-------TPALEYLSLLGNVACPNELVSLEKDEEDYKRYRCFVLYKLPNL 115
L +H L EV L + + N+ L LE ++ Y FV++ L L
Sbjct: 297 GLENHDLLEVINLEDNKIAELREIEYIKNLPILRVLNLLENPIQEKSEYWFFVIFMLLRL 356
Query: 116 KFLDAQKVTRQEREEAL 132
LD +K+ +E+ A+
Sbjct: 357 TELDQKKIKVEEKVSAV 373
Score = 29.6 bits (65), Expect = 1.8
Identities = 17/45 (37%), Positives = 26/45 (57%)
Query: 21 LSAFRSLEELILDNNQLGDDLVLPGLPRLHTLTLNKNRITDLENL 65
LSA+ +L +LILD N++ + L L L+L N+IT + L
Sbjct: 211 LSAYHALTKLILDGNEIEEISGLEMCNNLIHLSLANNKITTINGL 255
>gi|120953300 leucine-rich repeats and IQ motif containing 1 isoform 1
[Homo sapiens]
Length = 1722
Score = 40.0 bits (92), Expect = 0.001
Identities = 34/106 (32%), Positives = 50/106 (47%), Gaps = 16/106 (15%)
Query: 20 GLSAFRSLEELILDNNQLGDDLVLPGLPRLHTLTLNKNRITDLENLLDHLAEVTPALEYL 79
GL + ++L++LILD+NQL + L P + L + N +TD+E + E L+ L
Sbjct: 964 GLESLKNLQQLILDHNQLINTKGLCDTPTIVYLDCSHNHLTDVEGV-----ENCGLLQIL 1018
Query: 80 SLLGNVACPNELVSLEK---------DEEDYKRYRCFVLYKLPNLK 116
L GN +EL SLE D+ F Y LP L+
Sbjct: 1019 KLQGNYL--SELPSLENLVLLRELHLDDNSISTVEAFSSYWLPLLQ 1062
Score = 30.4 bits (67), Expect = 1.0
Identities = 30/94 (31%), Positives = 44/94 (46%), Gaps = 12/94 (12%)
Query: 5 LSLSGNHSSNKRSLEGLSAFRSLEELILDNNQLGDDLVLPG--LPRLHTLTLNKNRITDL 62
L L GN+ S SLE L R EL LD+N + LP L +T+++N +T +
Sbjct: 1018 LKLQGNYLSELPSLENLVLLR---ELHLDDNSISTVEAFSSYWLPLLQNITISQNSLTKI 1074
Query: 63 ENLLDHLAEVTPALEYLSLLGNVACPNELVSLEK 96
L + +LE L + N C ++L S K
Sbjct: 1075 VPLFHFV-----SLEKLDVSHN--CLSDLKSAIK 1101
Score = 27.3 bits (59), Expect = 8.7
Identities = 24/70 (34%), Positives = 32/70 (45%), Gaps = 6/70 (8%)
Query: 24 FRSLEELILDNNQLGDDLV----LPGLPRLHTLTLNKNRITDLENLLDHLAEVTPALEYL 79
F SLE+L + +N L D LH L+L N + N D L +V PAL L
Sbjct: 1080 FVSLEKLDVSHNCLSDLKSAIKWFDACYSLHELSLTGNPLLQETNWRDSLLKVLPALRIL 1139
Query: 80 SLLGNVACPN 89
+ GN+ N
Sbjct: 1140 N--GNILNSN 1147
>gi|120953243 leucine-rich repeats and IQ motif containing 1 isoform 2
[Homo sapiens]
Length = 1336
Score = 40.0 bits (92), Expect = 0.001
Identities = 34/106 (32%), Positives = 50/106 (47%), Gaps = 16/106 (15%)
Query: 20 GLSAFRSLEELILDNNQLGDDLVLPGLPRLHTLTLNKNRITDLENLLDHLAEVTPALEYL 79
GL + ++L++LILD+NQL + L P + L + N +TD+E + E L+ L
Sbjct: 964 GLESLKNLQQLILDHNQLINTKGLCDTPTIVYLDCSHNHLTDVEGV-----ENCGLLQIL 1018
Query: 80 SLLGNVACPNELVSLEK---------DEEDYKRYRCFVLYKLPNLK 116
L GN +EL SLE D+ F Y LP L+
Sbjct: 1019 KLQGNYL--SELPSLENLVLLRELHLDDNSISTVEAFSSYWLPLLQ 1062
Score = 30.4 bits (67), Expect = 1.0
Identities = 30/94 (31%), Positives = 44/94 (46%), Gaps = 12/94 (12%)
Query: 5 LSLSGNHSSNKRSLEGLSAFRSLEELILDNNQLGDDLVLPG--LPRLHTLTLNKNRITDL 62
L L GN+ S SLE L R EL LD+N + LP L +T+++N +T +
Sbjct: 1018 LKLQGNYLSELPSLENLVLLR---ELHLDDNSISTVEAFSSYWLPLLQNITISQNSLTKI 1074
Query: 63 ENLLDHLAEVTPALEYLSLLGNVACPNELVSLEK 96
L + +LE L + N C ++L S K
Sbjct: 1075 VPLFHFV-----SLEKLDVSHN--CLSDLKSAIK 1101
Score = 27.3 bits (59), Expect = 8.7
Identities = 24/70 (34%), Positives = 32/70 (45%), Gaps = 6/70 (8%)
Query: 24 FRSLEELILDNNQLGDDLV----LPGLPRLHTLTLNKNRITDLENLLDHLAEVTPALEYL 79
F SLE+L + +N L D LH L+L N + N D L +V PAL L
Sbjct: 1080 FVSLEKLDVSHNCLSDLKSAIKWFDACYSLHELSLTGNPLLQETNWRDSLLKVLPALRIL 1139
Query: 80 SLLGNVACPN 89
+ GN+ N
Sbjct: 1140 N--GNILNSN 1147
>gi|15529980 leucine rich repeat containing 46 [Homo sapiens]
Length = 321
Score = 39.3 bits (90), Expect = 0.002
Identities = 42/130 (32%), Positives = 58/130 (44%), Gaps = 22/130 (16%)
Query: 16 RSLEGLSAFRSLEELILDNNQLGDDLVLPGLPRLHTLTLNKNRITDLENLLDHLAEVTPA 75
R+LEGL ++L L L N++ L +P L L+L N+I +ENLLD P
Sbjct: 60 RNLEGL---QNLHSLYLQGNKIQQIENLACIPSLRFLSLAGNQIRQVENLLD-----LPC 111
Query: 76 LEYLSLLGNV-------ACPNELVSLEKDEE---DYKRYRCFVLYKLPNLKFLDAQKVTR 125
L++L L N+ P L+ L + YR V LP L LD Q V
Sbjct: 112 LQFLDLSENLIETLKLDEFPQSLLILNLSGNSCTNQDGYRELVTEALPLLLDLDGQPVVE 171
Query: 126 Q----EREEA 131
+ E +EA
Sbjct: 172 RWISDEEDEA 181
Score = 35.4 bits (80), Expect = 0.032
Identities = 25/64 (39%), Positives = 33/64 (51%), Gaps = 8/64 (12%)
Query: 24 FRSLEELI---LDNNQLGDDLVLPGLPRLHTLTLNKNRITDLENLLDHLAEVTPALEYLS 80
F +L+EL LD + L GL LH+L L N+I +ENL P+L +LS
Sbjct: 40 FHTLDELQTVRLDREGITTIRNLEGLQNLHSLYLQGNKIQQIENL-----ACIPSLRFLS 94
Query: 81 LLGN 84
L GN
Sbjct: 95 LAGN 98
>gi|53828918 Rab geranylgeranyltransferase alpha [Homo sapiens]
Length = 567
Score = 38.9 bits (89), Expect = 0.003
Identities = 24/63 (38%), Positives = 36/63 (57%), Gaps = 3/63 (4%)
Query: 17 SLEGLSAFRSLEELILDNNQLGDDLVLPGL---PRLHTLTLNKNRITDLENLLDHLAEVT 73
SL+G++ L+EL+L NN+L VL L PRL L L N + +L+ LAE+
Sbjct: 500 SLDGVTNLPRLQELLLCNNRLQQPAVLQPLASCPRLVLLNLQGNPLCQAVGILEQLAELL 559
Query: 74 PAL 76
P++
Sbjct: 560 PSV 562
Score = 30.0 bits (66), Expect = 1.3
Identities = 26/78 (33%), Positives = 36/78 (46%), Gaps = 2/78 (2%)
Query: 10 NHSSNKRSLEGLSAFRSLEELILDNNQLGDDLVLPGLPRLHTLTLNKNRITDLENLLDHL 69
+H+ + L+A R LE L +N + + LPRL L L NR+ +L L
Sbjct: 471 SHNRLRTLPPALAALRCLEVLQASDNAIESLDGVTNLPRLQELLLCNNRLQQ-PAVLQPL 529
Query: 70 AEVTPALEYLSLLGNVAC 87
A P L L+L GN C
Sbjct: 530 AS-CPRLVLLNLQGNPLC 546
>gi|33469951 Rab geranylgeranyltransferase alpha [Homo sapiens]
Length = 567
Score = 38.9 bits (89), Expect = 0.003
Identities = 24/63 (38%), Positives = 36/63 (57%), Gaps = 3/63 (4%)
Query: 17 SLEGLSAFRSLEELILDNNQLGDDLVLPGL---PRLHTLTLNKNRITDLENLLDHLAEVT 73
SL+G++ L+EL+L NN+L VL L PRL L L N + +L+ LAE+
Sbjct: 500 SLDGVTNLPRLQELLLCNNRLQQPAVLQPLASCPRLVLLNLQGNPLCQAVGILEQLAELL 559
Query: 74 PAL 76
P++
Sbjct: 560 PSV 562
Score = 30.0 bits (66), Expect = 1.3
Identities = 26/78 (33%), Positives = 36/78 (46%), Gaps = 2/78 (2%)
Query: 10 NHSSNKRSLEGLSAFRSLEELILDNNQLGDDLVLPGLPRLHTLTLNKNRITDLENLLDHL 69
+H+ + L+A R LE L +N + + LPRL L L NR+ +L L
Sbjct: 471 SHNRLRTLPPALAALRCLEVLQASDNAIESLDGVTNLPRLQELLLCNNRLQQ-PAVLQPL 529
Query: 70 AEVTPALEYLSLLGNVAC 87
A P L L+L GN C
Sbjct: 530 AS-CPRLVLLNLQGNPLC 546
>gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 family,
member E isoform 1 [Homo sapiens]
Length = 268
Score = 37.7 bits (86), Expect = 0.006
Identities = 37/103 (35%), Positives = 50/103 (48%), Gaps = 18/103 (17%)
Query: 18 LEGLS-AFRSLEELILDNNQLGDDLVLPGLPRLHTLTLNKNRITDLENLLDHLAEVTPAL 76
+EGL+ F+ LE L + N +L LP L +L L L+ N I+ L+ LAE P L
Sbjct: 34 IEGLNDTFKELEFLSMANVELSSLARLPSLNKLRKLELSDNIIS---GGLEVLAEKCPNL 90
Query: 77 EYLSLLGNVACPNELVSLEKDEEDYKRYRCFVLYKLPNLKFLD 119
YL+L GN +L ++E L L NLK LD
Sbjct: 91 TYLNLSGNKI--KDLSTVE------------ALQNLKNLKSLD 119
>gi|116268109 nucleotide-binding oligomerization domains 27 [Homo
sapiens]
Length = 1866
Score = 37.7 bits (86), Expect = 0.006
Identities = 22/48 (45%), Positives = 28/48 (58%), Gaps = 6/48 (12%)
Query: 19 EGLSAFRSLEELILDNNQLGD------DLVLPGLPRLHTLTLNKNRIT 60
E L A SLEEL L +NQ+GD +LPGLP L + L+ N I+
Sbjct: 1600 EALRAATSLEELDLSHNQIGDAGVQHLATILPGLPELRKIDLSGNSIS 1647
Score = 28.9 bits (63), Expect = 3.0
Identities = 18/43 (41%), Positives = 25/43 (58%), Gaps = 6/43 (13%)
Query: 26 SLEELILDNNQLGDDL------VLPGLPRLHTLTLNKNRITDL 62
+LE ++L N LGD+ VLP + RL + L KN+IT L
Sbjct: 1769 ALEVILLSWNLLGDEAAAELAQVLPQMGRLKRVDLEKNQITAL 1811
Score = 28.5 bits (62), Expect = 3.9
Identities = 17/39 (43%), Positives = 22/39 (56%), Gaps = 6/39 (15%)
Query: 27 LEELILDNNQLGDDLVL------PGLPRLHTLTLNKNRI 59
L+E+ +NQL D +VL P LPRL L L+ N I
Sbjct: 744 LKEVSFRDNQLSDQVVLNIVEVLPHLPRLRKLDLSSNSI 782
>gi|194239701 tubulin folding cofactor E-like [Homo sapiens]
Length = 424
Score = 37.4 bits (85), Expect = 0.008
Identities = 40/135 (29%), Positives = 65/135 (48%), Gaps = 17/135 (12%)
Query: 3 KYLSLSGNHSSNKRSLEGLSA-FRSLEELILDNNQLG-----DDLVLPGLPRLHTLTLNK 56
K L ++ N+ + + L F SL+ L+L NN L DD + P L +++L+K
Sbjct: 177 KLLHITDNNLQDWTEIRKLGVMFPSLDTLVLANNHLNAIEEPDDSLARLFPNLRSISLHK 236
Query: 57 NRITDLENLLDHLAEVTPALEYLSLLGNVACPNELVSLEKDEEDYKRYRCFVLYKLPNLK 116
+ + E++ D L P LE + LLG L+ EE K V+ +LP++
Sbjct: 237 SGLQSWEDI-DKLNSF-PKLEEVRLLGI-----PLLQPYTTEERRK----LVIARLPSVS 285
Query: 117 FLDAQKVTRQEREEA 131
L+ VT ERE++
Sbjct: 286 KLNGSVVTDGEREDS 300
>gi|194239699 tubulin folding cofactor E-like [Homo sapiens]
Length = 424
Score = 37.4 bits (85), Expect = 0.008
Identities = 40/135 (29%), Positives = 65/135 (48%), Gaps = 17/135 (12%)
Query: 3 KYLSLSGNHSSNKRSLEGLSA-FRSLEELILDNNQLG-----DDLVLPGLPRLHTLTLNK 56
K L ++ N+ + + L F SL+ L+L NN L DD + P L +++L+K
Sbjct: 177 KLLHITDNNLQDWTEIRKLGVMFPSLDTLVLANNHLNAIEEPDDSLARLFPNLRSISLHK 236
Query: 57 NRITDLENLLDHLAEVTPALEYLSLLGNVACPNELVSLEKDEEDYKRYRCFVLYKLPNLK 116
+ + E++ D L P LE + LLG L+ EE K V+ +LP++
Sbjct: 237 SGLQSWEDI-DKLNSF-PKLEEVRLLGI-----PLLQPYTTEERRK----LVIARLPSVS 285
Query: 117 FLDAQKVTRQEREEA 131
L+ VT ERE++
Sbjct: 286 KLNGSVVTDGEREDS 300
>gi|117414162 sodium channel associated protein 2 isoform a [Homo
sapiens]
Length = 1032
Score = 37.0 bits (84), Expect = 0.011
Identities = 41/152 (26%), Positives = 62/152 (40%), Gaps = 39/152 (25%)
Query: 11 HSSNKRSLEGLSAFRSLEELILDNNQLGDDLVLPGLPRLHTLTLNKNRITDLENL----- 65
H +N +E + +L+ L L +NQ+ L L +L TL L+ N IT +E L
Sbjct: 51 HCNNISKIEAIDHIWNLQHLDLSSNQISRIEGLNTLTKLCTLNLSCNLITKVEGLEELIN 110
Query: 66 ----------LDHLAEVTPA------LEYLSLLGN--------VACPNEL-----VSLEK 96
+D L+ + P L Y+ L N + C L + LEK
Sbjct: 111 LTRLNVSYNHIDDLSGLIPLHGIKHKLRYIDLHSNRIDSIHHLLQCMVGLHFLTNLILEK 170
Query: 97 DEED-----YKRYRCFVLYKLPNLKFLDAQKV 123
D +D YR +L LP L+ LD + +
Sbjct: 171 DGDDNPVCRLPGYRAVILQTLPQLRILDCKNI 202
>gi|55743114 leucine rich repeat containing 49 [Homo sapiens]
Length = 686
Score = 37.0 bits (84), Expect = 0.011
Identities = 30/94 (31%), Positives = 47/94 (50%), Gaps = 2/94 (2%)
Query: 1 MEKYLSLSGNHSSNKRSLEGLSAFRSLEELILDNNQLGDDLVLPGLPRLHTLTLNKNRIT 60
++K +SL + + + GLS R L L+L N++ L L L L L+ N+IT
Sbjct: 133 LQKLISLD-LYDNQIEEISGLSTLRCLRVLLLGKNRIKKISNLENLKSLDVLDLHGNQIT 191
Query: 61 DLENLLDHLAEVTPALEYLSLLGNVACPNELVSL 94
+EN ++HL E+ + L +V N L SL
Sbjct: 192 KIEN-INHLCELRVLNLARNFLSHVDNLNGLDSL 224
Score = 34.7 bits (78), Expect = 0.054
Identities = 36/131 (27%), Positives = 60/131 (45%), Gaps = 17/131 (12%)
Query: 3 KYLSLSGNHSSNKRSLEGLSAFRSLEELILDNNQLGDDLVLPGLPRLHTLTLNKNRITDL 62
+ L+L+ N S+ +L GL SL EL L +NQ+ + LP L L L+ N I+
Sbjct: 203 RVLNLARNFLSHVDNLNGLD---SLTELNLRHNQITFVRDVDNLPCLQHLFLSFNNISSF 259
Query: 63 ENLLDHLAEVTPALEYLSLLGNVACPNELVSLEKDEEDYKRYRCFVLYKLPNLKFLDAQK 122
+++ L S L ++ ++ E Y+ VL + L+ LD ++
Sbjct: 260 DSV--------SCLADSSSLSDITFDGNPIAQE------SWYKHTVLQNMMQLRQLDMKR 305
Query: 123 VTRQEREEALV 133
+T +ER A V
Sbjct: 306 ITEEERRMASV 316
Score = 30.0 bits (66), Expect = 1.3
Identities = 23/67 (34%), Positives = 33/67 (49%), Gaps = 5/67 (7%)
Query: 18 LEGLSAFRSLEELILDNNQLGDDLVLPGLPRLHTLTLNKNRITDLENLLDHLAEVTPALE 77
++ +S + L L L +NQ+ + L L L L L KNRI + NL E +L+
Sbjct: 127 IQNISNLQKLISLDLYDNQIEEISGLSTLRCLRVLLLGKNRIKKISNL-----ENLKSLD 181
Query: 78 YLSLLGN 84
L L GN
Sbjct: 182 VLDLHGN 188
>gi|206725447 leucine rich repeat containing 23 isoform a [Homo
sapiens]
Length = 343
Score = 35.8 bits (81), Expect = 0.024
Identities = 40/143 (27%), Positives = 56/143 (39%), Gaps = 17/143 (11%)
Query: 27 LEELILDNNQLGDDLVLPGLPRLHTLTLNKNRITDLENLLDHLAEVTPALEYLSLLGNVA 86
L+ L L N L L L L TL L N+I L + +L+YL+L GN+
Sbjct: 202 LKNLYLAQNMLKKVEGLEDLSNLTTLHLRDNQIDTLSGFSREMK----SLQYLNLRGNMV 257
Query: 87 CP-------------NELVSLEKDEEDYKRYRCFVLYKLPNLKFLDAQKVTRQEREEALV 133
LV L+ D YR L ++P L+ LD + +ER EA V
Sbjct: 258 ANLGELAKLRDLPKLRALVLLDNPCTDETSYRQEALVQMPYLERLDKEFYEEEERAEADV 317
Query: 134 RGVFMKVVKPKASSEDVASSPER 156
+K K + PE+
Sbjct: 318 IRQRLKEEKEQEPEPQRDLEPEQ 340
>gi|42542396 leucine rich repeat containing 23 isoform a [Homo
sapiens]
Length = 343
Score = 35.8 bits (81), Expect = 0.024
Identities = 40/143 (27%), Positives = 56/143 (39%), Gaps = 17/143 (11%)
Query: 27 LEELILDNNQLGDDLVLPGLPRLHTLTLNKNRITDLENLLDHLAEVTPALEYLSLLGNVA 86
L+ L L N L L L L TL L N+I L + +L+YL+L GN+
Sbjct: 202 LKNLYLAQNMLKKVEGLEDLSNLTTLHLRDNQIDTLSGFSREMK----SLQYLNLRGNMV 257
Query: 87 CP-------------NELVSLEKDEEDYKRYRCFVLYKLPNLKFLDAQKVTRQEREEALV 133
LV L+ D YR L ++P L+ LD + +ER EA V
Sbjct: 258 ANLGELAKLRDLPKLRALVLLDNPCTDETSYRQEALVQMPYLERLDKEFYEEEERAEADV 317
Query: 134 RGVFMKVVKPKASSEDVASSPER 156
+K K + PE+
Sbjct: 318 IRQRLKEEKEQEPEPQRDLEPEQ 340
>gi|62912474 leucine-rich repeat-containing G protein-coupled
receptor 6 isoform 3 [Homo sapiens]
Length = 828
Score = 35.0 bits (79), Expect = 0.042
Identities = 25/59 (42%), Positives = 33/59 (55%), Gaps = 3/59 (5%)
Query: 5 LSLSGNHSSNKRSLEGLSAFRSLEELILDNNQLG--DDLVLPGLPRLHTLTLNKNRITD 61
L LSGNH S+ + S SL+ L+L NNQLG L LP L +L LN N++ +
Sbjct: 52 LRLSGNHLSHIPG-QAFSGLYSLKILMLQNNQLGGIPAEALWELPSLQSLDLNYNKLQE 109
>gi|239752518 PREDICTED: similar to leucine rich repeat containing
50, partial [Homo sapiens]
Length = 489
Score = 34.7 bits (78), Expect = 0.054
Identities = 36/131 (27%), Positives = 60/131 (45%), Gaps = 17/131 (12%)
Query: 3 KYLSLSGNHSSNKRSLEGLSAFRSLEELILDNNQLGDDLVLPGLPRLHTLTLNKNRITDL 62
+ L+L+ N S+ +L GL SL EL L +NQ+ + LP L L L+ N I+
Sbjct: 28 RVLNLARNFLSHVDNLNGLD---SLTELNLRHNQITFVRDVDNLPCLQHLFLSFNNISSF 84
Query: 63 ENLLDHLAEVTPALEYLSLLGNVACPNELVSLEKDEEDYKRYRCFVLYKLPNLKFLDAQK 122
+++ L S L ++ ++ E Y+ VL + L+ LD ++
Sbjct: 85 DSV--------SCLADSSSLSDITFDGNPIAQE------SWYKHTVLQNMMQLRQLDMKR 130
Query: 123 VTRQEREEALV 133
+T +ER A V
Sbjct: 131 ITEEERRMASV 141
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.134 0.379
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,488,171
Number of Sequences: 37866
Number of extensions: 319266
Number of successful extensions: 1134
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 19
Number of HSP's successfully gapped in prelim test: 73
Number of HSP's that attempted gapping in prelim test: 1044
Number of HSP's gapped (non-prelim): 160
length of query: 198
length of database: 18,247,518
effective HSP length: 97
effective length of query: 101
effective length of database: 14,574,516
effective search space: 1472026116
effective search space used: 1472026116
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.5 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.