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Search of human proteins with 7661936
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7661936 scaffold attachment factor B2 [Homo sapiens]
(953 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7661936 scaffold attachment factor B2 [Homo sapiens] 1924 0.0
gi|21264343 scaffold attachment factor B [Homo sapiens] 1272 0.0
gi|63176611 modulator of estrogen induced transcription isoform ... 451 e-126
gi|62244004 modulator of estrogen induced transcription isoform ... 448 e-125
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 110 8e-24
gi|148746195 trichohyalin [Homo sapiens] 102 1e-21
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 98 3e-20
gi|4503509 eukaryotic translation initiation factor 3, subunit 1... 97 9e-20
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 95 3e-19
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 92 2e-18
gi|239747891 PREDICTED: hypothetical protein [Homo sapiens] 90 9e-18
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 90 1e-17
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 90 1e-17
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 90 1e-17
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 89 1e-17
gi|22035606 mitogen-activated protein kinase kinase kinase kinas... 89 2e-17
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 89 3e-17
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 89 3e-17
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 88 3e-17
gi|22035602 mitogen-activated protein kinase kinase kinase kinas... 87 6e-17
gi|239757964 PREDICTED: hypothetical protein [Homo sapiens] 87 7e-17
gi|22035604 mitogen-activated protein kinase kinase kinase kinas... 86 1e-16
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 86 2e-16
gi|56549694 enabled homolog isoform a [Homo sapiens] 86 2e-16
gi|39930375 enabled homolog isoform b [Homo sapiens] 86 2e-16
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 86 2e-16
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 83 1e-15
gi|239747174 PREDICTED: hypothetical protein XP_002343931, parti... 82 3e-15
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] 80 7e-15
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 79 2e-14
>gi|7661936 scaffold attachment factor B2 [Homo sapiens]
Length = 953
Score = 1924 bits (4984), Expect = 0.0
Identities = 953/953 (100%), Positives = 953/953 (100%)
Query: 1 MAETLPGSGDSGPGTASLGPGVAETGTRRLSELRVIDLRAELKKRNLDTGGNKSVLMERL 60
MAETLPGSGDSGPGTASLGPGVAETGTRRLSELRVIDLRAELKKRNLDTGGNKSVLMERL
Sbjct: 1 MAETLPGSGDSGPGTASLGPGVAETGTRRLSELRVIDLRAELKKRNLDTGGNKSVLMERL 60
Query: 61 KKAVKEEGQDPDEIGIELEATSKKSAKRCVKGLKMEEEGTEDNGLEDDSRDGQEDMEASL 120
KKAVKEEGQDPDEIGIELEATSKKSAKRCVKGLKMEEEGTEDNGLEDDSRDGQEDMEASL
Sbjct: 61 KKAVKEEGQDPDEIGIELEATSKKSAKRCVKGLKMEEEGTEDNGLEDDSRDGQEDMEASL 120
Query: 121 ENLQNMGMMDMSVLDETEVANSSAPDFGEDGTDGLLDSFCDSKEYVAAQLRQLPAQPPEH 180
ENLQNMGMMDMSVLDETEVANSSAPDFGEDGTDGLLDSFCDSKEYVAAQLRQLPAQPPEH
Sbjct: 121 ENLQNMGMMDMSVLDETEVANSSAPDFGEDGTDGLLDSFCDSKEYVAAQLRQLPAQPPEH 180
Query: 181 AVDGEGFKNTLETSSLNFKVTPDIEESLLEPENEKILDILGETCKSEPVKEESSELEQPF 240
AVDGEGFKNTLETSSLNFKVTPDIEESLLEPENEKILDILGETCKSEPVKEESSELEQPF
Sbjct: 181 AVDGEGFKNTLETSSLNFKVTPDIEESLLEPENEKILDILGETCKSEPVKEESSELEQPF 240
Query: 241 AQDTSSVGPDRKLAEEEDLFDSAHPEEGDLDLASESTAHAQSSKADSLLAVVKREPAEQP 300
AQDTSSVGPDRKLAEEEDLFDSAHPEEGDLDLASESTAHAQSSKADSLLAVVKREPAEQP
Sbjct: 241 AQDTSSVGPDRKLAEEEDLFDSAHPEEGDLDLASESTAHAQSSKADSLLAVVKREPAEQP 300
Query: 301 GDGERTDCEPVGLEPAVEQSSAASELAEASSEELAEAPTEAPSPEARDSKEDGRKFDFDA 360
GDGERTDCEPVGLEPAVEQSSAASELAEASSEELAEAPTEAPSPEARDSKEDGRKFDFDA
Sbjct: 301 GDGERTDCEPVGLEPAVEQSSAASELAEASSEELAEAPTEAPSPEARDSKEDGRKFDFDA 360
Query: 361 CNEVPPAPKESSTSEGADQKMSSFKEEKDIKPIIKDEKGRVGSGSGRNLWVSGLSSTTRA 420
CNEVPPAPKESSTSEGADQKMSSFKEEKDIKPIIKDEKGRVGSGSGRNLWVSGLSSTTRA
Sbjct: 361 CNEVPPAPKESSTSEGADQKMSSFKEEKDIKPIIKDEKGRVGSGSGRNLWVSGLSSTTRA 420
Query: 421 TDLKNLFSKYGKVVGAKVVTNARSPGARCYGFVTMSTSDEATKCISHLHRTELHGRMISV 480
TDLKNLFSKYGKVVGAKVVTNARSPGARCYGFVTMSTSDEATKCISHLHRTELHGRMISV
Sbjct: 421 TDLKNLFSKYGKVVGAKVVTNARSPGARCYGFVTMSTSDEATKCISHLHRTELHGRMISV 480
Query: 481 EKAKNEPAGKKLSDRKECEVKKEKLSSVDRHHSVEIKIEKTVIKKEEKIEKKEEKKPEDI 540
EKAKNEPAGKKLSDRKECEVKKEKLSSVDRHHSVEIKIEKTVIKKEEKIEKKEEKKPEDI
Sbjct: 481 EKAKNEPAGKKLSDRKECEVKKEKLSSVDRHHSVEIKIEKTVIKKEEKIEKKEEKKPEDI 540
Query: 541 KKEEKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVKTTSRSKERSSKSQD 600
KKEEKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVKTTSRSKERSSKSQD
Sbjct: 541 KKEEKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVKTTSRSKERSSKSQD 600
Query: 601 RKSESKEKRDILSFDKIKEQRERERQRQREREIRETERRREREQREREQRLEAFHERKEK 660
RKSESKEKRDILSFDKIKEQRERERQRQREREIRETERRREREQREREQRLEAFHERKEK
Sbjct: 601 RKSESKEKRDILSFDKIKEQRERERQRQREREIRETERRREREQREREQRLEAFHERKEK 660
Query: 661 ARLQRERLQLECQRQRLERERMERERLERERMRVERERRKEQERIHREREELRRQQEQLR 720
ARLQRERLQLECQRQRLERERMERERLERERMRVERERRKEQERIHREREELRRQQEQLR
Sbjct: 661 ARLQRERLQLECQRQRLERERMERERLERERMRVERERRKEQERIHREREELRRQQEQLR 720
Query: 721 YEQERRPGRRPYDLDRRDDAYWPEGKRVAMEDRYRADFPRPDHRFHDFDHRDRGQYQDHA 780
YEQERRPGRRPYDLDRRDDAYWPEGKRVAMEDRYRADFPRPDHRFHDFDHRDRGQYQDHA
Sbjct: 721 YEQERRPGRRPYDLDRRDDAYWPEGKRVAMEDRYRADFPRPDHRFHDFDHRDRGQYQDHA 780
Query: 781 IDRREGSRPMMGDHRDGQHYGDDRHGHGGPPERHGRDSRDGWGGYGSDKRLSEGRGLPPP 840
IDRREGSRPMMGDHRDGQHYGDDRHGHGGPPERHGRDSRDGWGGYGSDKRLSEGRGLPPP
Sbjct: 781 IDRREGSRPMMGDHRDGQHYGDDRHGHGGPPERHGRDSRDGWGGYGSDKRLSEGRGLPPP 840
Query: 841 PRGGRDWGEHNQRLEEHQARAWQGAMDAGAASREHARWQGGERGLSGPSGPGHMASRGGV 900
PRGGRDWGEHNQRLEEHQARAWQGAMDAGAASREHARWQGGERGLSGPSGPGHMASRGGV
Sbjct: 841 PRGGRDWGEHNQRLEEHQARAWQGAMDAGAASREHARWQGGERGLSGPSGPGHMASRGGV 900
Query: 901 AGRGGFAQGGHSQGHVVPGGGLEGGGVASQDRGSRVPHPHPHPPPYPHFTRRY 953
AGRGGFAQGGHSQGHVVPGGGLEGGGVASQDRGSRVPHPHPHPPPYPHFTRRY
Sbjct: 901 AGRGGFAQGGHSQGHVVPGGGLEGGGVASQDRGSRVPHPHPHPPPYPHFTRRY 953
>gi|21264343 scaffold attachment factor B [Homo sapiens]
Length = 915
Score = 1272 bits (3291), Expect = 0.0
Identities = 673/958 (70%), Positives = 774/958 (80%), Gaps = 48/958 (5%)
Query: 1 MAETLPGSGDSGP-GTASLGPGVAETGTRRLSELRVIDLRAELKKRNLDTGGNKSVLMER 59
MAETL G GDSG G A+L +ETGTRRLS+LRVIDLRAEL+KRN+D+ GNKSVLMER
Sbjct: 1 MAETLSGLGDSGAAGAAALSSASSETGTRRLSDLRVIDLRAELRKRNVDSSGNKSVLMER 60
Query: 60 LKKAVKEEGQDPDEIGIELEATSKKSAKRCVKGLKMEEEGTEDNGLEDDSRDGQEDMEAS 119
LKKA+++EG +PDEI I E +KK++KR KG K EEEG EDNGLE++S DGQED+E S
Sbjct: 61 LKKAIEDEGGNPDEIEITSEG-NKKTSKRSSKGRKPEEEGVEDNGLEENSGDGQEDVETS 119
Query: 120 LENLQNMGMMDMSVLDETEVANSSAPDFGEDG-TDGLLDSFCDSKEYVAAQLRQLPAQPP 178
LENLQ++ +MD+SVLDE E+ N S D ED D L +S DS+E V ++++LP Q
Sbjct: 120 LENLQDIDIMDISVLDEAEIDNGSVADCVEDDDADNLQESLSDSRELVEGEMKELPEQLQ 179
Query: 179 EHAVDGEGFKNTLETSSLNFKVTPDIEESLLEPENEKILDILGETCKSEPVKEESSELEQ 238
EHA++ + N L+TSS +F + +IEE LEPENEKILDILGETCKSEPVKEESSELEQ
Sbjct: 180 EHAIEDKETINNLDTSSSDFTILQEIEEPSLEPENEKILDILGETCKSEPVKEESSELEQ 239
Query: 239 PFAQDTSSVGPDRKLAEEEDLFDSAHPEEGDLDLASESTAHAQSSKADSLLAVVKREPAE 298
PFAQDTSSVGPDRKLAEEEDLFDSAHPEEGDLDLASESTAHAQSSKADSLLAVVKREPAE
Sbjct: 240 PFAQDTSSVGPDRKLAEEEDLFDSAHPEEGDLDLASESTAHAQSSKADSLLAVVKREPAE 299
Query: 299 QPGDGERTDCEPVGLEPAVEQSSAASELAEASSEELAEAPTEAPSPEARDSKEDGRKFDF 358
QPGDGERTDCEPVGLEPAVEQSSAASELAEASSEELAEAPTEAPSPEARDSKEDGRKFDF
Sbjct: 300 QPGDGERTDCEPVGLEPAVEQSSAASELAEASSEELAEAPTEAPSPEARDSKEDGRKFDF 359
Query: 359 DACNEVPPAPKESSTSEGADQKMSSFKEEKDIKPIIKDEKGRVGSGSGRNLWVSGLSSTT 418
DACNEVPPAPKESSTSEGADQKMSS +++ D K + K+EKGR S GRN WVSGLSSTT
Sbjct: 360 DACNEVPPAPKESSTSEGADQKMSSPEDDSDTKRLSKEEKGR--SSCGRNFWVSGLSSTT 417
Query: 419 RATDLKNLFSKYGKVVGAKVVTNARSPGARCYGFVTMSTSDEATKCISHLHRTELHGRMI 478
RATDLKNLFSKYGKVVGAKVVTNARSPGARCYGFVTMST++EATKCI+HLH+TELHG+MI
Sbjct: 418 RATDLKNLFSKYGKVVGAKVVTNARSPGARCYGFVTMSTAEEATKCINHLHKTELHGKMI 477
Query: 479 SVEKAKNEPAGKKLSDRKECEVKKEKLSSVDRHHSVEIKIEKTVIKKEEKIEKKEEKKPE 538
SVEKAKNEP GKK SD+++ + KKEK S+ DR T +K+++K ++K++ K
Sbjct: 478 SVEKAKNEPVGKKTSDKRDSDGKKEKSSNSDR---------STNLKRDDKCDRKDDAKKG 528
Query: 539 D--IKKEEKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVKTTSRSKERSS 596
D ++ KDQD+ KPGP+ RSR TKSGSRG ERTVVMDKSKG PVISVK TS SKER+S
Sbjct: 529 DDGSGEKSKDQDDQKPGPSERSRATKSGSRGTERTVVMDKSKGVPVISVK-TSGSKERAS 587
Query: 597 KSQDRKSESKEKRDILSFDKIKEQRERERQRQREREIRETERRREREQREREQRLEAFHE 656
KSQDRKS S+EKR ++SFDK+KE R + R+ E R RE+ EREQR++A E
Sbjct: 588 KSQDRKSASREKRSVVSFDKVKEPR-----KSRDSE----SHSRVRERSEREQRMQAQWE 638
Query: 657 RKEKARLQRERLQLECQRQRLERERMERERLERERMRVERERRKEQERIHREREELRRQQ 716
R+E+ RL+ R +L QRQRLERERMERERLERERM VE ERR+EQERIHREREELRRQQ
Sbjct: 639 REERERLEIARERLAFQRQRLERERMERERLERERMHVEHERRREQERIHREREELRRQQ 698
Query: 717 EQLRYEQERRPG-RRPYDLDRRDDAYWPEGKRVAMEDRYRADFPRPDHRFHDFDHRDRGQ 775
E LRYEQERRP RRPYDLDRRDDAYWPE KR A+++RY +DF R D RFHDFDHRDRG+
Sbjct: 699 E-LRYEQERRPAVRRPYDLDRRDDAYWPEAKRAALDERYHSDFNRQD-RFHDFDHRDRGR 756
Query: 776 YQDHAIDRREGSRPMMGDHRDGQHYGDDRHGHGGPPERHGRDSRDGWGGYGSDKRLSEGR 835
Y DH++DRREGSR MMG+ R+GQHY +RH G PERHGRDSRDGWGGYGSDKR+SEGR
Sbjct: 757 YPDHSVDRREGSRSMMGE-REGQHY-PERH---GGPERHGRDSRDGWGGYGSDKRMSEGR 811
Query: 836 GLPPPPRGGRDWGEHNQRLEEHQARAWQGAMDAGAASREHARWQGGERGLSGPSGPGHMA 895
GLPPPPR RDWG+H +R ++ R+WQG D G R+H RWQGGER +SG SGPGHM
Sbjct: 812 GLPPPPR--RDWGDHGRREDD---RSWQGTADGGMMDRDHKRWQGGERSMSGHSGPGHMM 866
Query: 896 SRGGVAGRGGFAQGGHSQGHVVPGGGLEGGGVASQDRGSRVPHPHPHPPPYPHFTRRY 953
+RGG++GRG FA GG S+GH +P GG++ GG Q RGSR P FTRRY
Sbjct: 867 NRGGMSGRGSFAPGGASRGHPIPHGGMQ-GGFGGQSRGSR--------PSDARFTRRY 915
>gi|63176611 modulator of estrogen induced transcription isoform a
[Homo sapiens]
Length = 1034
Score = 451 bits (1161), Expect = e-126
Identities = 360/1034 (34%), Positives = 522/1034 (50%), Gaps = 147/1034 (14%)
Query: 11 SGPGTASLGPGVAETGTRRLSELRVIDLRAELKKRNLDTGGNKSVLMERLKKAVKEEGQD 70
+G AS G AE +++++LRVIDL++ELK+RNLD G K+VL+ RLK+A++EEG D
Sbjct: 5 TGAVAASAASGQAEG--KKITDLRVIDLKSELKRRNLDITGVKTVLISRLKQAIEEEGGD 62
Query: 71 PDEIGIELEATSKKSAKRCVKGLKMEEEGTEDNGLEDDSRDGQEDMEASLENLQNMGMMD 130
PD I EL ++ K+ KG + E E +G +AS+E D
Sbjct: 63 PDNI--ELTVSTDTPNKKPTKGKGKKHEADELSG------------DASVE--------D 100
Query: 131 MSVLDETEVANSSAPDFGEDGTDGLLDS--FCDSKEYVAAQLRQLPAQPPEHA---VDGE 185
+ + + E+ N A + +DG D L DS F +++E L A+ + A ++ E
Sbjct: 101 DAFIKDCELENQEAHE--QDGNDELKDSEEFGENEEENVHSKELLSAEENKRAHELIEAE 158
Query: 186 GF----KNTLETSSLNFKVTPD----IEESLLEPENEKILDILGETCKSEPVKEESSELE 237
G K +E+ + + D + E ENEK DI G + + E+
Sbjct: 159 GIEDIEKEDIESQEIEAQEGEDDTFLTAQDGEEEENEK--DIAGSG-------DGTQEVS 209
Query: 238 QPFAQDTSSVGPDRKLAEEEDLFDSAHPEEGD---LDLASESTAHAQSSKADSLLAVVKR 294
+P + S D EE + + E D + + +E A D LL K
Sbjct: 210 KPLPSEGSLAEADHTAHEEMEAHTTVKEAEDDNISVTIQAED-AITLDFDGDDLLETGKN 268
Query: 295 -----EPAEQPGDGERTDCEPVGLEPAVEQSSAASELAEASSEELAEA-PTEAPSPEARD 348
A +P DG+ + E + +A + + E+ + P E + E+
Sbjct: 269 VKITDSEASKPKDGQDAIAQSPEKESKDYEMNANHK--DGKKEDCVKGDPVEKEARESSK 326
Query: 349 SKEDGRKFDFDACNEVPPAPKESSTSEGADQKMSSFKEEKDIKPIIKDEKGRVGSGSG-- 406
E G K E K S++ + Q SS KE KD K KD+KG S SG
Sbjct: 327 KAESGDK-------EKDTLKKGPSSTGASGQAKSSSKESKDSKTSSKDDKGSTSSTSGSS 379
Query: 407 ----RNLWVSGLSSTTRATDLKNLFSKYGKVVGAKVVTNARSPGARCYGFVTMSTSDEAT 462
+N+WVSGLSS T+A DLKNLF KYGKV+ AKVVTNARSPGA+CYG VTMS+S E +
Sbjct: 380 GSSTKNIWVSGLSSNTKAADLKNLFGKYGKVLSAKVVTNARSPGAKCYGIVTMSSSTEVS 439
Query: 463 KCISHLHRTELHGRMISVEKAKNEPAGKKL----SDRKECEVKKEKLSSVDRHHSVEIKI 518
+CI+HLHRTELHG++ISVEK K +P+ K++ ++ +K ++ DR + +
Sbjct: 440 RCIAHLHRTELHGQLISVEKVKGDPSKKEMKKENDEKSSSRSSGDKKNTSDRSSKTQASV 499
Query: 519 EKTVIKKEEKIEKKEEKKPEDIKKEEKDQDELKPGPTNRSRVTKS------GSRGMERTV 572
+K + EK EKKE K + I+ +++ D G T+ S + KS S+ V
Sbjct: 500 KKEEKRSSEKSEKKESKDTKKIEGKDEKNDNGASGQTSES-IKKSEEKKRISSKSPGHMV 558
Query: 573 VMDKSKGEPVIS------VKTTSRSKERSSKSQDRKSESKEKR-DILSFDKIKEQRERER 625
++D++KG+ K RSKE+ S D+K + +R +IL F+K+KEQR RE
Sbjct: 559 ILDQTKGDHCRPSRRGRYEKIHGRSKEKERASLDKKRDKDYRRKEILPFEKMKEQRLREH 618
Query: 626 QRQREREIRETERRREREQRERE----QRLEAFHERKEKARLQRERLQLECQRQRLERER 681
+ ER R E RR RE ERE +R+ ER+E+ RLQRER +LE +RQ+LERER
Sbjct: 619 LVRFERLRRAMELRRRREIAERERRERERIRIIREREERERLQRERERLEIERQKLERER 678
Query: 682 MERERLERERMRVERERRKEQERIHREREELRRQQEQLRYEQERRPG-RRPYDLD-RRDD 739
MERERLERER+R+E+ERRKE ERI REREELRRQQ+QLRYEQE+R +RP D+D RRDD
Sbjct: 679 MERERLERERIRIEQERRKEAERIAREREELRRQQQQLRYEQEKRNSLKRPRDVDHRRDD 738
Query: 740 AYWPEGKRVAMEDRYR----ADFPRPDHRFHDFDHRDRGQY-------------QDHAID 782
YW E K+++++ R +D+ R +RF+DFDHR+RG++ +D +
Sbjct: 739 PYWSENKKLSLDTDARFGHGSDYSRQQNRFNDFDHRERGRFPESSAVQSSSFERRDRFVG 798
Query: 783 RREGSRPMMGDHRDG-------QHYGDDRHGHGGPPERHGRDS-RDGWGGYGSDKR--LS 832
+ EG + R+ +++ D R PP R+S R G ++R +
Sbjct: 799 QSEGKKARPTARREDPSFERYPKNFSDSRRNEPPPPRNELRESDRREVRGERDERRTVII 858
Query: 833 EGRGLPPPPRGGRDWGEHNQRLEEHQARAWQGAMDAGAASREHARWQGGERGLSGPS--- 889
R PR R+ G + R ++ +G+M R + R +SG S
Sbjct: 859 HDRPDITHPRHPREAGPNPSRPTSWKS---EGSMSTDKRETRVERPERSGREVSGHSVRG 915
Query: 890 -GPGHMAS----------RGGVAGRGGFAQGGHSQGHVVPGGGLEGGGVASQDRGSRVPH 938
PG+ +S RG + RGG +Q + HVV G + G + G
Sbjct: 916 APPGNRSSASGYGSREGDRGVITDRGGGSQHYPEERHVVERHGRDTSGPRKEWHGP---- 971
Query: 939 PHPHPPPYPHFTRR 952
P P H TRR
Sbjct: 972 --PSQGPSYHDTRR 983
>gi|62244004 modulator of estrogen induced transcription isoform b
[Homo sapiens]
Length = 1016
Score = 448 bits (1153), Expect = e-125
Identities = 360/1033 (34%), Positives = 518/1033 (50%), Gaps = 163/1033 (15%)
Query: 11 SGPGTASLGPGVAETGTRRLSELRVIDLRAELKKRNLDTGGNKSVLMERLKKAVKEEGQD 70
+G AS G AE +++++LRVIDL++ELK+RNLD G K+VL+ RLK+A++EEG D
Sbjct: 5 TGAVAASAASGQAEG--KKITDLRVIDLKSELKRRNLDITGVKTVLISRLKQAIEEEGGD 62
Query: 71 PDEIGIELEATSKKSAKRCVKGLKMEEEGTEDNGLEDDSRDGQEDMEASLENLQNMGMMD 130
PD I EL ++ K+ KG + E E +G +AS+E D
Sbjct: 63 PDNI--ELTVSTDTPNKKPTKGKGKKHEADELSG------------DASVE--------D 100
Query: 131 MSVLDETEVANSSAPDFGEDGTDGLLDSFCDSKEYVAAQLRQLPAQPPEHAVDGEGFKNT 190
+ + + E+ N A + +DG D L DS +E+ GE +
Sbjct: 101 DAFIKDCELENQEAHE--QDGNDELKDS----EEF------------------GENEEEN 136
Query: 191 LETSSLNFKVTPDIEESLLEPENEKILDILGETCKSEPVKEESSELEQPFAQDTSSVGPD 250
+ + L L+E E I DI E +S+ ++ + E DT D
Sbjct: 137 VHSKELLSAEENKRAHELIEAEG--IEDIEKEDIESQEIEAQEGE------DDTFLTAQD 188
Query: 251 RKLAEEEDLFDSAHPEEGDLDLASESTAHAQSSKA--DSLLAVVKREPAEQPGDGERTDC 308
EEE+ E D E AH +A D++ ++ E A D + D
Sbjct: 189 ---GEEEENEKEGSLAEADHTAHEEMEAHTTVKEAEDDNISVTIQAEDAITL-DFDGDDL 244
Query: 309 EPVGLEPAVEQSSAASELAEASSEELAEAPT-EAPSPEARDSKEDGRKFDFDACNEVPPA 367
G + S A+ + + +A++P E+ E + +DG+K D + V
Sbjct: 245 LETGKNVKITDSEASKP--KDGQDAIAQSPEKESKDYEMNANHKDGKKEDCVKGDPVEKE 302
Query: 368 PKESS-----------------TSEGAD-QKMSSFKEEKDIKPIIKDEKGRVGSGSG--- 406
+ESS +S GA Q SS KE KD K KD+KG S SG
Sbjct: 303 ARESSKKAESGDKEKDTLKKGPSSTGASGQAKSSSKESKDSKTSSKDDKGSTSSTSGSSG 362
Query: 407 ---RNLWVSGLSSTTRATDLKNLFSKYGKVVGAKVVTNARSPGARCYGFVTMSTSDEATK 463
+N+WVSGLSS T+A DLKNLF KYGKV+ AKVVTNARSPGA+CYG VTMS+S E ++
Sbjct: 363 SSTKNIWVSGLSSNTKAADLKNLFGKYGKVLSAKVVTNARSPGAKCYGIVTMSSSTEVSR 422
Query: 464 CISHLHRTELHGRMISVEKAKNEPAGKKL----SDRKECEVKKEKLSSVDRHHSVEIKIE 519
CI+HLHRTELHG++ISVEK K +P+ K++ ++ +K ++ DR + ++
Sbjct: 423 CIAHLHRTELHGQLISVEKVKGDPSKKEMKKENDEKSSSRSSGDKKNTSDRSSKTQASVK 482
Query: 520 KTVIKKEEKIEKKEEKKPEDIKKEEKDQDELKPGPTNRSRVTKS------GSRGMERTVV 573
K + EK EKKE K + I+ +++ D G T+ S + KS S+ V+
Sbjct: 483 KEEKRSSEKSEKKESKDTKKIEGKDEKNDNGASGQTSES-IKKSEEKKRISSKSPGHMVI 541
Query: 574 MDKSKGEPVIS------VKTTSRSKERSSKSQDRKSESKEKR-DILSFDKIKEQRERERQ 626
+D++KG+ K RSKE+ S D+K + +R +IL F+K+KEQR RE
Sbjct: 542 LDQTKGDHCRPSRRGRYEKIHGRSKEKERASLDKKRDKDYRRKEILPFEKMKEQRLREHL 601
Query: 627 RQREREIRETERRREREQRERE----QRLEAFHERKEKARLQRERLQLECQRQRLERERM 682
+ ER R E RR RE ERE +R+ ER+E+ RLQRER +LE +RQ+LERERM
Sbjct: 602 VRFERLRRAMELRRRREIAERERRERERIRIIREREERERLQRERERLEIERQKLERERM 661
Query: 683 ERERLERERMRVERERRKEQERIHREREELRRQQEQLRYEQERRPG-RRPYDLD-RRDDA 740
ERERLERER+R+E+ERRKE ERI REREELRRQQ+QLRYEQE+R +RP D+D RRDD
Sbjct: 662 ERERLERERIRIEQERRKEAERIAREREELRRQQQQLRYEQEKRNSLKRPRDVDHRRDDP 721
Query: 741 YWPEGKRVAMEDRYR----ADFPRPDHRFHDFDHRDRGQY-------------QDHAIDR 783
YW E K+++++ R +D+ R +RF+DFDHR+RG++ +D + +
Sbjct: 722 YWSENKKLSLDTDARFGHGSDYSRQQNRFNDFDHRERGRFPESSAVQSSSFERRDRFVGQ 781
Query: 784 REGSRPMMGDHRDG-------QHYGDDRHGHGGPPERHGRDS-RDGWGGYGSDKR--LSE 833
EG + R+ +++ D R PP R+S R G ++R +
Sbjct: 782 SEGKKARPTARREDPSFERYPKNFSDSRRNEPPPPRNELRESDRREVRGERDERRTVIIH 841
Query: 834 GRGLPPPPRGGRDWGEHNQRLEEHQARAWQGAMDAGAASREHARWQGGERGLSGPS---- 889
R PR R+ G + R ++ +G+M R + R +SG S
Sbjct: 842 DRPDITHPRHPREAGPNPSRPTSWKS---EGSMSTDKRETRVERPERSGREVSGHSVRGA 898
Query: 890 GPGHMAS----------RGGVAGRGGFAQGGHSQGHVVPGGGLEGGGVASQDRGSRVPHP 939
PG+ +S RG + RGG +Q + HVV G + G + G
Sbjct: 899 PPGNRSSASGYGSREGDRGVITDRGGGSQHYPEERHVVERHGRDTSGPRKEWHGP----- 953
Query: 940 HPHPPPYPHFTRR 952
P P H TRR
Sbjct: 954 -PSQGPSYHDTRR 965
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 110 bits (274), Expect = 8e-24
Identities = 116/475 (24%), Positives = 200/475 (42%), Gaps = 44/475 (9%)
Query: 481 EKAKNEPAGKKLSDRKECEVKKEKLSSVDRHHSVEIKIEKTVIKKEEKIEKKE-EKKPED 539
EK +N ++ +E E +++ + R + EK ++ ++ +++ E+ +
Sbjct: 118 EKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQK 177
Query: 540 IKKEEKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVKTTSRSKERS-SKS 598
++ EK++ E + R + K+ R ER ++ + + + +ER +
Sbjct: 178 EREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRK 237
Query: 599 QDRKSESKEKRDILSFDKIKEQRERERQRQREREIRETERRRERE-QREREQRLEAFHER 657
+R+ E + +R+ S + + +ERER+R R+R+ ++ RER+ R+R++R E E
Sbjct: 238 TEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRET 297
Query: 658 KEKARLQRERLQLECQRQRLERERMERERLERERMR-VERERRKEQERIHREREELRRQQ 716
+ K QRER + + ++ ERER ERER ERER R ER+R KE+ER + + E+ R++
Sbjct: 298 ERKRERQRERERERERNRKRERER-ERER-ERERQRETERDREKERERKRKRQTEMDRER 355
Query: 717 EQLRYEQERRPGRRPYDLDRRDDAYWPEGKRVAMEDRYRADFPRPDHRFHDFDHRDRGQY 776
+ + RR R + +R D + DR D R R + GQ
Sbjct: 356 NRQTGREGRRQAERERERERERDRQSAREREERERDR---DRDRQKERERQTEKDRDGQR 412
Query: 777 QDHAIDRREGSRPMMGDHRDGQHYGDDRHGHGGPPERHGRDSRDGWGGYGSDKRLSEGRG 836
+ RE R + G+ G +R G ER D G +R
Sbjct: 413 ETEKQREREKDR----ESERGRERGREREKQKG-RERDRERQTDRQAG---RQRKRSTLY 464
Query: 837 LPPPPRGGRDWGEHNQRLEEHQARAWQGAMDAGAASREHARWQGGERGLSGPSGPGHMAS 896
+ PPPR R + + W+ + + A+ W G AS
Sbjct: 465 VNPPPRTARSGVVQSDPNRPTRGIRWKSSPEDPKAASTRFPW-----------GRPAKAS 513
Query: 897 RGGVAGRGGF--------AQGGHSQGHVVPGGGLEGGGVASQDRGSRVPHPHPHP 943
RG VAGR + QGG G GG +++ S+ P P P
Sbjct: 514 RGRVAGRRRWEPRLGEKRGQGGE--------GRRPSGGFGTENPLSQAPSVFPGP 560
Score = 105 bits (262), Expect = 2e-22
Identities = 85/266 (31%), Positives = 134/266 (50%), Gaps = 21/266 (7%)
Query: 476 RMISVEKAKNEPAGKKLSDRKECEVKKEKLSSVDRHHSVEIKIEKTVIKKEEKIEKKEEK 535
R + K K +R+E E ++EK + + HS ++ + E++ E
Sbjct: 169 RQTERNRQKEREREKNRQERRERERQREKENKTEDRHS----------ERGRERERERET 218
Query: 536 KPEDIKKEEKDQDELKPGPTNRSRVTKS-GSRGMERTVVMDKSKGEPVISVKTTSRSKER 594
+ E +K + D++ + T R R ++ R ER DK + + R ++
Sbjct: 219 ETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKE 278
Query: 595 SSKSQDRKSESKEKRDILSFDKIKEQRERERQRQREREIRETERRRERE---QREREQRL 651
+ DRK + + +RD + K + QRERER+R+R R+ RE ER RERE QRE E+
Sbjct: 279 RERQTDRKRQRRTERDRETERKRERQRERERERERNRK-RERERERERERERQRETERDR 337
Query: 652 EAFHERKEKARLQRERLQLECQRQRLERERMERERLERERMRVERERRKEQERIHREREE 711
E ERK K + + +R + Q R R + ERER ERER ER+R+ +ER RER+
Sbjct: 338 EKERERKRKRQTEMDR-ERNRQTGREGRRQAERER-ERER---ERDRQSAREREERERDR 392
Query: 712 LR-RQQEQLRYEQERRPGRRPYDLDR 736
R RQ+E+ R ++ R G+R + R
Sbjct: 393 DRDRQKERERQTEKDRDGQRETEKQR 418
Score = 92.8 bits (229), Expect = 1e-18
Identities = 77/278 (27%), Positives = 136/278 (48%), Gaps = 35/278 (12%)
Query: 484 KNEPAGKKLSDRKECEVKKEKLSSVDRHHSVEIKIEKTVIKKEEKI-----EKKEEKKPE 538
+ E +K +E + K+E+ DRH + E+ +++E+ E+ +++ E
Sbjct: 61 ERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKE 120
Query: 539 DIKKEEKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVKTTSRSKERSSKS 598
+++E++++ + G R R T G R ER +K + + T R ++R ++
Sbjct: 121 RNRQKERERETEREGERGRDRQT-DGQRERERQRDAEKERE------RQTDRERQRQTER 173
Query: 599 QDRKSESKEKRDILSFDKIKEQRERERQRQREREIRETERRREREQREREQRLEAFHERK 658
+K +EK +E+RERERQR++E + + R RE RERE+ E ERK
Sbjct: 174 NRQKEREREKNR-------QERRERERQREKENKTEDRHSERGRE-RERERETETETERK 225
Query: 659 EKARLQRERLQLECQRQRLERERMERERLERERMR-VERERRKEQERIHREREELRRQQE 717
+ +R+R +++ ERER ++ ER R ER++ +E+ER R+R+ RRQ+E
Sbjct: 226 RQTDRERDR------QRKTEREREKQAERERASERETERDKERERER-DRDRDRDRRQKE 278
Query: 718 QLRYEQERRPGRRPYDLDRRDDAYWPEGKRVAMEDRYR 755
+ R +R R D + E KR +R R
Sbjct: 279 RERQTDRKRQRRTERDRE-------TERKRERQRERER 309
Score = 77.4 bits (189), Expect = 6e-14
Identities = 68/238 (28%), Positives = 111/238 (46%), Gaps = 12/238 (5%)
Query: 527 EKIEKKEEKKPEDIKKEEKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVK 586
E+ +KE ++ + ++ E++ D + + R K R ER +K + +
Sbjct: 55 ERNRQKERERRREKRQTERETDRKRERRREKDRHRKR-DRHRERQRDREKERERQTDRER 113
Query: 587 TTSRSKERSSKSQDRKSESKEKRDILSFDKIKEQRERERQRQREREI-----RETERRRE 641
R KER+ + ++R+ E++ + + + QRERERQR E+E RE +R+ E
Sbjct: 114 DRQREKERN-RQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTE 172
Query: 642 REQREREQRLEAFHERKEKARLQRERLQLECQRQRLERERMERER---LERERMRVERER 698
R +++ +R + ER+E+ R + + + E + RER ERER E ER R
Sbjct: 173 RNRQKEREREKNRQERRERERQREKENKTEDRHSERGRER-ERERETETETERKRQTDRE 231
Query: 699 RKEQERIHREREELRRQQEQLRYEQERRPGR-RPYDLDRRDDAYWPEGKRVAMEDRYR 755
R Q + RERE+ ++ E ER R R D DR D E +R R R
Sbjct: 232 RDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQR 289
Score = 74.7 bits (182), Expect = 4e-13
Identities = 68/271 (25%), Positives = 120/271 (44%), Gaps = 24/271 (8%)
Query: 536 KPEDIKKEEKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVKTTSRSKERS 595
K D E+++ + + + + + R ER D+ + + R KER
Sbjct: 47 KDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERE 106
Query: 596 SKSQDRKSESKEKRDILSFDKIKE-QRERERQRQREREIRETERRRERE-QREREQRLEA 653
++ + +EK ++ +E +RE ER R R+ + + ER R+R+ ++ERE++ +
Sbjct: 107 RQTDRERDRQREKERNRQKERERETEREGERGRDRQTD-GQRERERQRDAEKERERQTDR 165
Query: 654 FHERKEKARLQRERLQLECQRQRLERERMERERLERERMRVERERRKEQERIHREREELR 713
+R+ + Q+ER ERE+ +ER ERER R E+E + E R RE R
Sbjct: 166 ERQRQTERNRQKER----------EREKNRQERRERERQR-EKENKTEDRHSERGRERER 214
Query: 714 RQQEQLRYEQERRPGRRPYDLDRRDDAYWPEGKRVAMEDRYRADFPRPDHRFHDFDHRDR 773
++ + E++R+ R RD E +R +R RA + R+R
Sbjct: 215 ERETETETERKRQTDR------ERDRQRKTEREREKQAERERAS----ERETERDKERER 264
Query: 774 GQYQDHAIDRREGSRPMMGDHRDGQHYGDDR 804
+ +D DRR+ R D + + DR
Sbjct: 265 ERDRDRDRDRRQKERERQTDRKRQRRTERDR 295
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 102 bits (255), Expect = 1e-21
Identities = 175/835 (20%), Positives = 330/835 (39%), Gaps = 77/835 (9%)
Query: 24 ETGTRRLSELRVIDLRAELKKRN---LDTGGNKSVLMERLK--KAVKEEGQDPDEIGIEL 78
E R E R LR E ++R L + L +RL+ + ++ E ++ E ++
Sbjct: 493 EEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKR 552
Query: 79 EATSKKSAKRCVKGLKMEEEGTEDNGLEDDSRDGQE----DMEASLENLQNMGMMDMSVL 134
E + +R + LK E+E D L+ + Q+ + E LE ++
Sbjct: 553 EEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQ 612
Query: 135 DETEVANSSAPDFGEDGTDGLLDSFCDSKEYVAAQLRQLPAQPPEHAVDGEGFKNTLETS 194
+E + E+ LL S + +E QLR+ + E + E + LE
Sbjct: 613 EERREQRLKREEPEEERRQQLLKSE-EQEERRQQQLRREQQERREQRLKREEEEERLEQR 671
Query: 195 SLNFKVTPDIEESLLEPENEKILDILGETC-------KSEPVKEESSELEQPFAQDTSSV 247
E+ L E E E+ + + +SE +S +P Q+
Sbjct: 672 LKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQE---- 727
Query: 248 GPDRKLAEEEDLFDSAHPEEGDLDLASESTAHAQSSKADSLLAVVKREPAEQPGDG--ER 305
G R+ +EE E +L E AH Q + + + AE+ + +R
Sbjct: 728 GQRRRQEQEE----KRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQR 783
Query: 306 TDCEPVGLEPAVEQSSAASELAEASSEELAEAPTEAPSPEARDSKEDGRKFDFDACNEVP 365
P P EQ E E P E + R + + K E+
Sbjct: 784 LSARP----PLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREK-------ELQ 832
Query: 366 PAPKESSTSEGADQKMSSFKEEKDIKPIIKDEKGRVGSGSGRNLWVSGLSSTTRATDLKN 425
+E ++ +EE+D + +D++ R R+ R
Sbjct: 833 FLEEEEQLQRR--ERAQQLQEEED--GLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHT 888
Query: 426 LFSKYGKVVGAKVVTNARSPGARCYGFVTMSTSDEATKCISHLHRTELHGRMISVEKAKN 485
L++K A R + +E + R + R E+
Sbjct: 889 LYAK-----------PALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQ 937
Query: 486 EPAGKKLSDRKECEVKKEKLSSVDRHHSVEIKIEKTVIKKEEKIEKKEEKKPEDIKKEEK 545
+ + L + +E ++E+ + ++ K E+ + ++ EK ++E +K ++E +
Sbjct: 938 QEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQ 997
Query: 546 DQDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVKTTSRSKERSSKSQDRKSES 605
++E R + R + + + + + + + R +ER + ++ +
Sbjct: 998 QEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQ 1057
Query: 606 KEKRDILSFDK-IKEQRERERQRQREREIRETERRREREQREREQRLEAFHERKEKARLQ 664
+E+ +L ++ + ++E ERQ ++E E+++ E + RE+ E+ +R E + +E+ LQ
Sbjct: 1058 QEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQ 1117
Query: 665 RERLQL------ECQRQRLERERMERERLERE-----RMRVERERRKEQERIHREREELR 713
+E QL + +RQ LER+ E E +++E R E+ RR+E ER +RE EEL+
Sbjct: 1118 QEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQ 1177
Query: 714 RQQEQ-LRYEQERRPGRRPYDLDRRDDAYWPEGKRVAMEDRYRADFPRPDHRFHDFDHRD 772
+++EQ LR EQE+R R+ + R++ E +R + RYR + R D ++ ++
Sbjct: 1178 QEEEQLLREEQEKR--RQERERQYREE---EELQRQKRKQRYRDEDQRSDLKW-QWEPEK 1231
Query: 773 RGQYQDHAI---DRREGSRPMMGDH--RDGQHYGDDRHGHGGPPERHGRDSRDGW 822
+D+ + R + D RD Q D +H G ER R W
Sbjct: 1232 ENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRW 1286
Score = 98.2 bits (243), Expect = 3e-20
Identities = 73/317 (23%), Positives = 145/317 (45%), Gaps = 37/317 (11%)
Query: 494 DRKECEVKKEKLSSVDRHHSVEIKIEKTVIKKE-------------------------EK 528
+R+E ++E+L S H + E E+ + ++E E+
Sbjct: 182 EREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEE 241
Query: 529 IEKKEEKKPEDIKKEEKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVKTT 588
EK+ K+ ++KEE+ E +P + + R +ER + + + E +
Sbjct: 242 EEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLR 301
Query: 589 SRSKERSSKSQDRKSESKEKRDILSFDKIKEQRERERQRQREREIRETERRREREQRERE 648
+ R + ++R+ + +E+R+ + +E+R ++ R+ + E RE + RRE+E+ RE
Sbjct: 302 REQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERRE 361
Query: 649 QRLEAFHERKEKARLQRERLQLECQRQRLERERMERERLERERMRVERERRKEQERIHRE 708
Q+L E + + + R QL ++Q +++ RE+ R ++ RE++ +E+ R
Sbjct: 362 QQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRR 421
Query: 709 REELRRQQEQLRYEQERRPGRRPYDLDRRDDAYWPEGKRVAMEDRYRADFPRPDHRFHDF 768
++LRR+QE+ R+EQ+ RR L R + KR +R H+
Sbjct: 422 EQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETER------------HEQ 469
Query: 769 DHRDRGQYQDHAIDRRE 785
+ R + +D +RRE
Sbjct: 470 ERRKQQLKRDQEEERRE 486
Score = 97.4 bits (241), Expect = 5e-20
Identities = 67/246 (27%), Positives = 128/246 (52%), Gaps = 25/246 (10%)
Query: 517 KIEKTVIKKEEKIEKKEEKKPEDIKKEEKDQDELKPGPTNRSRVTKSGSRGMERTVVMDK 576
K E + K+EEK++++E ++ ++++EE+ +L+ R R + + R +
Sbjct: 248 KRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLR 307
Query: 577 SKGEPVISVKTTSRSKERSSKSQDRKSESKEKRDILSFDKIKEQRERERQRQREREIRET 636
K E + +E + Q+R+ + +E+R+ + +E+RE++ +R++E E RE
Sbjct: 308 RKQE-----EERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQ 362
Query: 637 ERRREREQREREQRLEAFHERKEKARLQRER-------------LQLECQ---RQRLERE 680
+ RRE+E+ REQ+L + + + +L+RE+ L+ E Q Q+L RE
Sbjct: 363 QLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 422
Query: 681 RMERERLERERMRVERERRKEQERIHREREE----LRRQQEQLRYEQERRPGRRPYDLDR 736
+ R E ER + E+ + ++R+ RE+EE L+R++E R+EQERR + D +
Sbjct: 423 QQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEE 482
Query: 737 RDDAYW 742
W
Sbjct: 483 ERRERW 488
Score = 91.7 bits (226), Expect = 3e-18
Identities = 107/419 (25%), Positives = 184/419 (43%), Gaps = 61/419 (14%)
Query: 495 RKECEVKKEKLSSVDRHHSVEIKIEKTVIKKEEKIEKKEEKKPEDIKKEEK---DQDELK 551
R+E ++++E+ ++ E ++ + + E+ E++ E+K E ++E++ +Q+E +
Sbjct: 396 RREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERR 455
Query: 552 PGPTNRSRVTKSGSRGMERTVVMDKS--KGEPVISVKTTSRSKERSSKSQDRKSESKEKR 609
+ ++ + D+ + E + ++ R +++ + Q + E +E+R
Sbjct: 456 DWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERR 515
Query: 610 DILSFDKIKEQRERERQRQREREI----RETERRRER----------EQREREQRLEAFH 655
+ ++K Q E ER +QR R RE E RRE+ EQ REQRL+
Sbjct: 516 E----QRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQ 571
Query: 656 E--------RKEKARLQR-ERLQLECQRQRLERERMER-ERLERERMRVERERRKEQER- 704
E R+E+ R QR +R Q E QRL+RE +ER E+ ER R++RE +E+ R
Sbjct: 572 EERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQ 631
Query: 705 --IHREREELRRQQEQLRYEQERRPGR---------------RPYDLDRRDDAYWPEGKR 747
+ E +E RRQQ+ R +QERR R R ++ +RR+ E +
Sbjct: 632 QLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQE 691
Query: 748 VAMEDRYRADFPRPDHRFH-DFDHR-----DRGQYQDHAIDRREGSRPMMGDHRDGQHYG 801
A E R ++ P+ + + D R R + Q+ R+E + Q
Sbjct: 692 QARE-RIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQE 750
Query: 802 DDRHGHGGPPERHGRDSRDGWGGYGSDKRLSEGRGLPPPPRGGRDWGEHNQRLEEHQAR 860
++R E RD W +R + PP R R E R EE Q R
Sbjct: 751 EERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQR---ERQLRAEERQQR 806
Score = 87.4 bits (215), Expect = 6e-17
Identities = 80/379 (21%), Positives = 179/379 (47%), Gaps = 40/379 (10%)
Query: 468 LHRTELHGRMISVEKA---------KNEPAGKKLSDRKECEVKKEKLSSVDRHHSVEIKI 518
LHR + + + E+ + + +K + ++ ++E+ + + ++
Sbjct: 1524 LHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRL 1583
Query: 519 EKTVIKKEEKIEKKEEKKPEDIKKEEKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSK 578
E+ ++++E+ E+K + + ++++E Q +L+ + R + + E + + +
Sbjct: 1584 EEQKVRRQEQ-ERKFMEDEQQLRRQE-GQQQLRQERDRKFREDEQLLQEREEQQLHRQER 1641
Query: 579 GEPVISVKTTSRSKERSSKSQ-DRKSESKEKRDILSFDKIKEQRERERQRQREREIRETE 637
+ + R +ER + + DR + +E+ +L + ++ R +ER R + RE +
Sbjct: 1642 DRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDR-KFREEEQQL 1700
Query: 638 RRREREQREREQRLEAFHERKEKARLQRERLQLECQRQRLERERMERERLERERMRVERE 697
RR+ERE++ ++ + + E+ + E+L+ E ++++L R+ R+ LE E++R ERE
Sbjct: 1701 RRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPERE 1760
Query: 698 ----RRKEQERIHREREELR--RQQEQLRYEQERRPGRRPYDL-----------DRRDDA 740
RR+E++R RE E+LR R+++QLR ++ R R L +RD
Sbjct: 1761 EQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGK 1820
Query: 741 YWPEGKRVAMED---RYRADFPRPDHRFHDFDHRDRGQYQDHAI-------DRREGSRPM 790
Y E +++ +E+ R R + R F +++ + ++ + R+E R +
Sbjct: 1821 YRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKL 1880
Query: 791 MGDHRDGQHYGDDRHGHGG 809
+H Q + RH G
Sbjct: 1881 REEHIRRQQKEEQRHRQVG 1899
Score = 85.5 bits (210), Expect = 2e-16
Identities = 75/313 (23%), Positives = 154/313 (49%), Gaps = 32/313 (10%)
Query: 470 RTELHGRMISVEKAKNEPAGKKLSDRKECEVKKEKLSSVDRHHSVEIKIEKTVIKKEEKI 529
R E R+ E+ K E ++ RKE +EKL + E++ E+ ++K E+
Sbjct: 230 RRERQDRVFQEEEEK-EWRKRETVLRKE----EEKLQEEEPQRQRELQEEEEQLRKLERQ 284
Query: 530 EKKEEKKPEDIKKEE-KDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVKTT 588
E + E++ E+ +++ + + +L+ R + R + + + E + +
Sbjct: 285 ELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQE 344
Query: 589 SRSKERSSKSQDRKSESKEKRDILSFDKIKEQRERERQRQREREIRETERRREREQRERE 648
R +++ + Q+ + ++ R ++ ++Q RE+Q +RE+++R ++ R +Q RE
Sbjct: 345 ERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRRE 404
Query: 649 QRLEAFHERKEKARLQRERL--------------QLECQRQRLERERMERE---RLERER 691
Q+L + + + +L+RE+ + E + QRL+RE+ ER + E E
Sbjct: 405 QQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEET 464
Query: 692 MRVERERRKEQERIHREREELRR------QQEQLRYEQERRPGR-RPYDLDRRDDAYWPE 744
R E+ERRK+Q + R++EE RR ++E+ R +QERR + R +RR+ +
Sbjct: 465 ERHEQERRKQQ--LKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQ 522
Query: 745 GKRVAMEDRYRAD 757
+ ++ R R++
Sbjct: 523 EEEERLQQRLRSE 535
Score = 84.0 bits (206), Expect = 6e-16
Identities = 62/285 (21%), Positives = 149/285 (52%), Gaps = 25/285 (8%)
Query: 470 RTELHGRMISVEKAKNEPAGKKLSDRKECEVKKEKLSSVDRHHSVEIKIEKTVIKKEEKI 529
R E R E+ + + ++ +R+E ++++E+ + +++ E+ ++E+++
Sbjct: 321 RREQQERREQQEERREQQLRREQEERREQQLRREQ---EEERREQQLRREQEEERREQQL 377
Query: 530 EKKEE-KKPEDIKKEE--KDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVK 586
++++ ++ + +++E+ + + +L+ R + + R + + + E +
Sbjct: 378 RREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEE-----E 432
Query: 587 TTSRSKERSSKSQDRKSESKEKRDILSFDKIKEQRERERQRQREREIRETERRREREQRE 646
+ E+ + Q K E +E+RD L ++ E+ E+ER++Q+ + +E ERR + E
Sbjct: 433 RHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLE 492
Query: 647 REQRLEAFHERKEKARLQRERLQLECQRQRLERERMERERLERERMRVERERRKEQ---- 702
E+R E R+++ R ++E + + +++ E ER+++ +++R E+E R+EQ
Sbjct: 493 EEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKR 552
Query: 703 ---ERIHREREE--LRRQQEQ-----LRYEQERRPGRRPYDLDRR 737
+R+ +ER E L+R+QE+ L+ E+ERR R + + R
Sbjct: 553 EEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEER 597
Score = 75.5 bits (184), Expect = 2e-13
Identities = 74/321 (23%), Positives = 155/321 (48%), Gaps = 37/321 (11%)
Query: 470 RTELHGRMISVEKAKNEPAGKKLSD------RKECEVK----KEKLSSVDRHHSVEIKIE 519
R + R E+ +++ G+K + R+E E K +++L +R + +
Sbjct: 1354 RRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRD 1413
Query: 520 KTVIKKEEKIEKKEE-----KKPEDIKKEEKD------QDELKPGPTNRSRVTKSGSRGM 568
+ ++E+++ ++E ++ + ++++E++ + +L+ + R + +
Sbjct: 1414 RKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQER 1473
Query: 569 ERTVVMDKSKGEPVISVKTTSRSKERSSKSQDRKSESKEKRDILSFDKIKEQRERERQRQ 628
E + + + + + R +ER DRK +E R K E+ ++ ++Q
Sbjct: 1474 EEQQLHRQERDRKFLEEEQQLRRQER-----DRKFREQELRSQEPERKFLEEEQQLHRQQ 1528
Query: 629 REREIRETE---RRREREQREREQRLEAFHERKEKARLQRERLQLECQRQ----RLERER 681
R+R+ + E RR+ER Q+ R+ R F E +E+ R +RE QL Q + RLE ++
Sbjct: 1529 RQRKFLQEEQQLRRQERGQQRRQDRDRKFRE-EEQLRQEREEQQLSRQERDRKFRLEEQK 1587
Query: 682 MERERLERERMRVERERRKE--QERIHREREELRRQQEQLRYEQERRPGRRPYDLDRRDD 739
+ R+ ER+ M E++ R++ Q+++ +ER+ R+ EQL E+E + R + DR+
Sbjct: 1588 VRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHR-QERDRKFL 1646
Query: 740 AYWPEGKRVAMEDRYRADFPR 760
P+ +R E + R D R
Sbjct: 1647 EEEPQLRRQEREQQLRHDRDR 1667
Score = 74.7 bits (182), Expect = 4e-13
Identities = 79/318 (24%), Positives = 155/318 (48%), Gaps = 39/318 (12%)
Query: 496 KECEVKKEKLSSVDRHHSVEIKIEKTVIKKEEKIEKKEEKKPEDIKKEEKDQDELKPGPT 555
++ E ++ + DRH E ++E+ +E+K K+ ++K ++ K+ +++ E K
Sbjct: 1277 RDREQERRRWQQRDRHFPEEEQLER----EEQKEAKRRDRKSQEEKQLLREEREEK---- 1328
Query: 556 NRSRVTKSGSRGMERTVVMDKSKGEPVISVKTTSRSKERSSKSQDRKSESKEKRDILSFD 615
R ++ + E ++ + + +P+ R +ER DRK +E R
Sbjct: 1329 --RRRQETDRKFREEEQLLQEREEQPL-------RRQER-----DRKFREEELRHQEQGR 1374
Query: 616 KIKEQRERERQRQRERE---IRETERRR--EREQREREQRLEAFHERKEKARLQRERLQL 670
K E E +R R++ERE ++E ++ R EREQ+ R+ R F E +++ Q +
Sbjct: 1375 KFLE--EEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKF 1432
Query: 671 ECQRQRLERERMERERLERE-RMRVERERR-KEQERIHREREE--LRRQQEQLRY-EQER 725
+ Q++ R+ ER+ LE E ++R ER R+ +E+E++ +EREE L RQ+ ++ E+E+
Sbjct: 1433 REEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQ 1492
Query: 726 RPGRRPYDLD-RRDDAYWPEGKRVAMEDRYRADFPRPDHRF----HDFDHRDRGQYQDHA 780
+ R+ D R + E +R +E+ + + +F ++RGQ +
Sbjct: 1493 QLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQD 1552
Query: 781 IDRREGSRPMMGDHRDGQ 798
DR+ + R+ Q
Sbjct: 1553 RDRKFREEEQLRQEREEQ 1570
Score = 70.1 bits (170), Expect = 9e-12
Identities = 87/394 (22%), Positives = 176/394 (44%), Gaps = 81/394 (20%)
Query: 481 EKAKNEPAGKKLSDRKECEVKKEKLSSVDRHHSVEIKIEKTVIKKEEKIEKKEEK----K 536
EK + + ++ + +E + ++E+L +R ++E+ +KEE+++++EE+ +
Sbjct: 1039 EKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQY-RKEEELQQEEEQLLREE 1097
Query: 537 PEDIKKEEKD-----QDELKPGPTNRSRVTKSGSRGME-----RTVVMDKSKGEPVISVK 586
PE +++E++ ++EL+ R + R E R + + E ++ +
Sbjct: 1098 PEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREE 1157
Query: 587 TTSRSKERSSKSQDRKSE-SKEKRDILSFDKIKEQRERERQRQREREIRETERR------ 639
R ++ + + E +E+ +L ++ K ++ERERQ + E E++ +R+
Sbjct: 1158 PEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDE 1217
Query: 640 ---------------------------REREQ---------REREQRLEAFH---ERKEK 660
RE EQ R+R+ + + H E++E+
Sbjct: 1218 DQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQER 1277
Query: 661 ARLQRERLQLECQRQRLERERMERERLERERMRVERERRKEQERIHREREELRRQQ---- 716
R Q R + R E E++ERE ++E R +R+ ++E++ + EREE RR+Q
Sbjct: 1278 DREQERRRWQQRDRHFPEEEQLEREE-QKEAKRRDRKSQEEKQLLREEREEKRRRQETDR 1336
Query: 717 -----EQLRYEQERRPGRRPYDLDRR---DDAYWPEGKRVAMEDRYRADFPRPDHRFHDF 768
EQL E+E +P RR + DR+ ++ E R +E+ R + +F
Sbjct: 1337 KFREEEQLLQEREEQPLRR-QERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKE 1395
Query: 769 DHRDRGQYQDHAI--DR----REGSRPMMGDHRD 796
+ + R Q ++ + DR RE + + RD
Sbjct: 1396 EQQLRCQEREQQLRQDRDRKFREEEQQLSRQERD 1429
Score = 69.3 bits (168), Expect = 2e-11
Identities = 82/371 (22%), Positives = 173/371 (46%), Gaps = 47/371 (12%)
Query: 481 EKAKNEPAGKKLSDRKECEVKKEKLSSVDRHHSVEIKIEKTVIKKEEKIEKKEEKKPEDI 540
++ ++ P ++L ++ E K+ S + EK ++++E + +++ ++
Sbjct: 1288 QRDRHFPEEEQLEREEQKEAKRRDRKSQE---------EKQLLREEREEKRRRQETDRKF 1338
Query: 541 KKEEKDQDELKPGPTNRS-----------RVTKSGSRGMERTVVMDKSKGE-PVISVKTT 588
++EE+ E + P R R + G + +E + + + E + +
Sbjct: 1339 REEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQ 1398
Query: 589 SRSKERSSK-SQDRKSESKEKRDILSFDKI-----KEQRERERQRQREREIRETERR--- 639
R +ER + QDR + +E+ LS + +E+++ RQ +RER+ E E++
Sbjct: 1399 LRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQ-ERERKFLEEEQQLRQ 1457
Query: 640 -REREQREREQRLEAFHERKEKARLQRERLQLECQRQRLERERMERERLERERMRVERER 698
R R+ RE EQ L+ E ++ R +R+R LE + Q+L R+ +R+ E+E E ER
Sbjct: 1458 ERHRKFREEEQLLQE-REEQQLHRQERDRKFLE-EEQQLRRQERDRKFREQELRSQEPER 1515
Query: 699 R--KEQERIHREREELRRQQEQLRYEQERRPGRRPYDLDRRDDAYWPEGKRVAME-DRYR 755
+ +E++++HR++ + + QE+ + ++ R +R D DR+ + E +++ E + +
Sbjct: 1516 KFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRK----FREEEQLRQEREEQQ 1571
Query: 756 ADFPRPDHRFHDFDHRDRGQYQ------DHAIDRREGSRPMMGDHRDGQHYGDDRHGHGG 809
D +F + + R Q Q D RR+ + + RD + D++
Sbjct: 1572 LSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQER 1631
Query: 810 PPERHGRDSRD 820
++ R RD
Sbjct: 1632 EEQQLHRQERD 1642
Score = 67.8 bits (164), Expect = 5e-11
Identities = 63/261 (24%), Positives = 120/261 (45%), Gaps = 49/261 (18%)
Query: 569 ERTVVMDKSKGEPVISVKTTSRSKERSSKSQDRKSESKEKRDILSFDKIKEQRERERQRQ 628
+ +++ D+ + E + R E + R+ +++R++ ++ E++ER QR
Sbjct: 106 KESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRD 165
Query: 629 REREIRETERRREREQREREQRLE-------AFHERK----EKARLQRERLQL------E 671
R+R E R+R+ Q E+R E HE + E+ +RE L+L E
Sbjct: 166 RQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREE 225
Query: 672 CQRQRLERE-------------------RMERERLERERMRVERERRKEQERIHR-EREE 711
Q+QR ER+ R E E+L+ E + +RE ++E+E++ + ER+E
Sbjct: 226 KQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQE 285
Query: 712 LRR-------QQEQLRYEQERRPGRRPYDLDRRDDAYWPEGKRVAMEDRYRADFPRPDHR 764
LRR QQ++LR EQ+ R + +++++ + +R E+R R
Sbjct: 286 LRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQE- 344
Query: 765 FHDFDHRDRGQYQDHAIDRRE 785
+ R++ ++ +RRE
Sbjct: 345 ----ERREQQLRREQEEERRE 361
Score = 66.6 bits (161), Expect = 1e-10
Identities = 60/263 (22%), Positives = 127/263 (48%), Gaps = 29/263 (11%)
Query: 502 KEKLSSVDRHHSVEIKIEKTVIKKEEKIEKKEEKKPEDIKKEEKDQDELKPGPTNRSRVT 561
+++ S D H + + E+ ++ + ++++ PE+ + E ++Q E K
Sbjct: 1259 RDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAK---------- 1308
Query: 562 KSGSRGMERTVVMDKSKGEPVISVKTTSRSKERSSKSQDRKSESKEKRDILSFDKIKEQR 621
+ + E ++ + + E K + +R + +++ + +E++ + ++ ++ R
Sbjct: 1309 RRDRKSQEEKQLLREEREE-----KRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFR 1363
Query: 622 ERE-RQRQREREIRETERRREREQREREQRLEAFHERKEKARLQRERLQLECQRQRLERE 680
E E R +++ R+ E E+R R++RER+ F + +++ R Q QL R R RE
Sbjct: 1364 EEELRHQEQGRKFLEEEQRLRRQERERK-----FLKEEQQLRCQEREQQLRQDRDRKFRE 1418
Query: 681 RMER-ERLERERMRVERE---RRKEQERIHREREELRRQQEQLRYEQERR--PGRRPYDL 734
++ R ER+R E E RR+E+ER E E+ RQ+ ++ +E + R L
Sbjct: 1419 EEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQL 1478
Query: 735 DR--RDDAYWPEGKRVAMEDRYR 755
R RD + E +++ ++R R
Sbjct: 1479 HRQERDRKFLEEEQQLRRQERDR 1501
Score = 62.0 bits (149), Expect = 3e-09
Identities = 55/276 (19%), Positives = 135/276 (48%), Gaps = 16/276 (5%)
Query: 519 EKTVIKKEEKIEKKEEKKPEDIKKEEKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSK 578
E+ +++E+++ ++ +K + ++ ++++E + R R + + R K +
Sbjct: 1445 ERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFR 1504
Query: 579 GEPVISVKTTSR--SKERSSKSQDRKSESKEKRDILSFDKIKEQRERERQRQREREIRET 636
+ + S + + +E+ Q R+ + ++ L + +QR ++R R + RE +
Sbjct: 1505 EQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDR-KFREEEQL 1563
Query: 637 ERRREREQREREQRLEAFHERKEKARLQ-RERLQLECQRQRLERERMERERLERERMRVE 695
+ RE +Q R++R F ++K R Q +ER +E ++Q +E ++ R ER+R E
Sbjct: 1564 RQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFRE 1623
Query: 696 RE---RRKEQERIHREREELRRQQEQLRYEQERRPGRRPYDLDRR---DDAYWPEGKRVA 749
E + +E++++HR+ + + +E+ + ++ R + +D DR+ ++ EG+
Sbjct: 1624 DEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQ 1683
Query: 750 MEDRYRADFPRPDHRFHDFDHRDRGQYQDHAIDRRE 785
+ + R D +F + + + R Q ++ + E
Sbjct: 1684 LRRQER------DRKFREEEQQLRRQERERKFLQEE 1713
Score = 57.4 bits (137), Expect = 6e-08
Identities = 51/251 (20%), Positives = 134/251 (53%), Gaps = 28/251 (11%)
Query: 492 LSDRKECEVKKEKLSSVDRHHSVEIKIEKTVIKKEEKIEKKEEKKPEDIKKEEKDQDELK 551
L + +E ++++++ R +++ ++ ++ + ++++++ + ++++++ +++++L
Sbjct: 1676 LQEGEEQQLRRQERDRKFREEEQQLRRQE---RERKFLQEEQQLRRQELERKFREEEQL- 1731
Query: 552 PGPTNRSRVTKSGSRGMER-TVVMDKSKGEPVISVKTTSRS-KERSSKSQDRKSESKEKR 609
R + R ER ++++ + P + R ++R + +++ + +E++
Sbjct: 1732 -----RQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQ 1786
Query: 610 DILSFD-----KIKEQRERERQRQRER-EIRETERRREREQ---REREQRLEAFHERKEK 660
+ S + + +EQ +ER+ Q+ R + R+ + R E EQ E+EQRL R+E+
Sbjct: 1787 QLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRL-----RQER 1841
Query: 661 ARLQRERLQLECQRQRLERERMERERLERERMRVERERRKEQERIHREREELRRQQE--Q 718
R R Q Q ++ RE E + E ++ R ERER+ +E I R+++E +R ++ +
Sbjct: 1842 DRQYRAEEQFATQ-EKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGE 1900
Query: 719 LRYEQERRPGR 729
++ ++ + GR
Sbjct: 1901 IKSQEGKGHGR 1911
Score = 52.4 bits (124), Expect = 2e-06
Identities = 44/175 (25%), Positives = 85/175 (48%), Gaps = 12/175 (6%)
Query: 599 QDRKSESKEKRDILSFDKIKEQRERERQRQREREIRETERRREREQREREQRLEAFHERK 658
+++++ K +L + +E + R R R+ E +RRR++ ++E+E+ L E+
Sbjct: 97 EEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQK-RQEQERELAEGEEQS 155
Query: 659 EK-ARLQ---RERLQLECQRQRLERERMERERLERERMRV----ERERRKEQERI-HRER 709
EK RL+ R+R E RQR E + E R E E+++ E E ++E++ RE
Sbjct: 156 EKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRREL 215
Query: 710 EELRRQQEQLRYEQERRPGRRPYDLDRRDDAYWPEGKRVAMEDRYRADFPRPDHR 764
ELRR+ + + +Q R R+ ++ W + + V ++ + P +
Sbjct: 216 LELRRKGREEKQQQRRE--RQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQ 268
Score = 48.5 bits (114), Expect = 3e-05
Identities = 45/159 (28%), Positives = 77/159 (48%), Gaps = 18/159 (11%)
Query: 622 ERERQRQREREIRETERRREREQREREQRLEAFHE----RKEKARLQRERLQLECQRQRL 677
E +R R +E +RR+E +QR E R E R+ + R ++ER E + Q
Sbjct: 97 EEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSE 156
Query: 678 ERERMERERLERERMRVERERRKEQERIHREREELRRQQEQLR----YEQERRPGRRPYD 733
++ER+E+ +R + R+R++ Q EREE R ++EQL+ +E E P
Sbjct: 157 KQERLEQRDRQRRDEELWRQRQEWQ-----EREERRAEEEQLQSCKGHETEEFPDEE--Q 209
Query: 734 LDRRDDAYWPEGKRVAMEDRYRADFPRPDHRFHDFDHRD 772
L RR+ E +R E++ + R D F + + ++
Sbjct: 210 LRRRE---LLELRRKGREEKQQQRRERQDRVFQEEEEKE 245
Score = 38.1 bits (87), Expect = 0.039
Identities = 32/147 (21%), Positives = 62/147 (42%), Gaps = 12/147 (8%)
Query: 656 ERKEKARLQRERLQLECQRQRLERERMERERLERERMRVERERRKEQERIHREREELRRQ 715
+ +++AR + L+ +RQ ++ R E + E +R R+K QE+ E +
Sbjct: 96 DEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQS 155
Query: 716 QEQLRYEQERRPGRRPYDLDRRDDAYWPEGKRVAMEDRYRADFPR----PDHRFHDFDHR 771
++Q R EQ D RRD+ W + + + RA+ + H +F
Sbjct: 156 EKQERLEQR--------DRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDE 207
Query: 772 DRGQYQDHAIDRREGSRPMMGDHRDGQ 798
++ + ++ RR+G R+ Q
Sbjct: 208 EQLRRRELLELRRKGREEKQQQRRERQ 234
Score = 37.7 bits (86), Expect = 0.051
Identities = 35/198 (17%), Positives = 89/198 (44%), Gaps = 3/198 (1%)
Query: 468 LHRTELHGRMISVEKAKNEPAGKKLSDRKECEVKKEKLSSVDRHHSVEIKIEKTVIKKEE 527
L R EL + E+ + E ++L ++ E+ +++ ++ K E
Sbjct: 1716 LRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFRE 1775
Query: 528 KIEKKEEKKPEDIKKEEKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVKT 587
+ + ++E++ + ++ +E D+ + + R + R +R + + + +
Sbjct: 1776 EEQLRQEREEQQLRSQESDR-KFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQE 1834
Query: 588 TSRSKERSSKSQDRKSESKEKRDILSFDKIKEQRERERQRQREREIRETERRRER--EQR 645
+ER + + + + +++ ++ ++ E++R+++RER++RE RR++ EQR
Sbjct: 1835 QRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQR 1894
Query: 646 EREQRLEAFHERKEKARL 663
R+ E K RL
Sbjct: 1895 HRQVGEIKSQEGKGHGRL 1912
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 98.2 bits (243), Expect = 3e-20
Identities = 94/306 (30%), Positives = 150/306 (49%), Gaps = 48/306 (15%)
Query: 482 KAKNEPAGKKLSDRKECEVKKEKLSSVDRHHSVEIKIEKTVIKKEEKIEKKEEKKPEDIK 541
K E GKK +R+E E ++ +R E + E+ ++E + E++ EK+ E +
Sbjct: 289 KKLEEEKGKKEKERQEIEKERR-----ERERERERERERREREREREREREREKEKERER 343
Query: 542 KEEKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVKTTSRSKERSSKSQDR 601
+ E+D+D R R TK R +R + R +ERSS
Sbjct: 344 ERERDRD--------RDR-TKERDRDRDRE--------------RDRDRDRERSSDRNKD 380
Query: 602 KSESKEKRDILSFDKIKEQRERERQRQREREIRETERRREREQREREQRLEAFHERKEKA 661
+S S+EK S D+ +RERER+R+RERE RE ER RERE RERE+ E E K+K
Sbjct: 381 RSRSREK----SRDR---ERERERERERERE-RERERERERE-RERERERERERE-KDKK 430
Query: 662 RLQRERLQLECQRQRLERERMERERLERERMR--VERERRKEQERIHREREELRRQQEQL 719
R + E + +R++LER+ E+E +ER++ RER+K +E E R++E
Sbjct: 431 RDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMA 490
Query: 720 RYEQERRPGRRPYDLDRRDDAYWPEGKRVAMEDRYRADFPRPDHRFHDFDHRDRGQYQDH 779
+ + + YD DR D Y+ + A++ R R + + D RDR + ++
Sbjct: 491 KEAKRLKEFLEDYDDDRDDPKYY---RGSALQKRL-----RDREKEMEADERDRKREKEE 542
Query: 780 AIDRRE 785
+ R+
Sbjct: 543 LEEIRQ 548
Score = 97.4 bits (241), Expect = 5e-20
Identities = 108/449 (24%), Positives = 194/449 (43%), Gaps = 49/449 (10%)
Query: 392 PIIKDEKGRVGSGSGRNLWVSGLSSTTRATDLKNLFSKYGKVVGAKVVTNARSPGARCYG 451
P +K ++ G ++V +S ++ L +K G V+ K V A S + +G
Sbjct: 72 PGLKAKENDENCGPTTTVFVGNISEKASDMLIRQLLAKCGLVLSWKRVQGA-SGKLQAFG 130
Query: 452 FVTMSTSDEATKCISHLHRTELHGRMISVE------------KAKNEPAGKKLSDRKECE 499
F + + + LH ++ + + V+ KAK + +
Sbjct: 131 FCEYKEPESTLRALRLLHDLQIGEKKLLVKVDAKTKAQLDEWKAKKKASNGNARPETVTN 190
Query: 500 VKKEKLSSVDRHHSVEIKIEKTVIKKEEKIEKKEEKKPEDI----KKEEKDQDELKPGPT 555
+E L + IK V+ +E E + D KK+EK +D + P
Sbjct: 191 DDEEALDEETKRRDQMIKGAIEVLIREYSSELNAPSQESDSHPRKKKKEKKEDIFRRFPV 250
Query: 556 NR----SRVTKSGSRGMERTVVMDKSKGEPVISVKTTSRSKERSSKSQDRKSESKEKRDI 611
+TK +E M++ K + + + S+ ++ K ++ K + +++R
Sbjct: 251 APLIPYPLITKEDINAIE----MEEDKRDLIS--REISKFRDTHKKLEEEKGKKEKERQE 304
Query: 612 LSFDKIKEQRERERQRQREREIRETERRRERE-QREREQRLEAFHER---KEKAR----- 662
+ ++ + +RERER+R+R RE ER RERE ++ERE+ E +R KE+ R
Sbjct: 305 IEKERRERERERERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRE 364
Query: 663 LQRERLQLECQRQRLERERMERERLERERMRVERERRKEQERIHREREELRRQQEQLRYE 722
R+R + + +R R + +RER R ERER +E+ER RERE R ++ + E
Sbjct: 365 RDRDRDRERSSDRNKDRSRSREKSRDRERER-ERERERERER-ERERERERERERERERE 422
Query: 723 QERRPGRRPYDLDRRDDAYWPEGKRVAMEDRYRADFPRPDHRFHDFDHRDR---GQYQDH 779
+ER ++ + +DAY +R +E + R R +++ R+R +Y+
Sbjct: 423 REREKDKKRDREEDEEDAY----ERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKE 478
Query: 780 AIDRREGSRPMMGDHRD----GQHYGDDR 804
A E R M + + + Y DDR
Sbjct: 479 AEREEERRREMAKEAKRLKEFLEDYDDDR 507
Score = 54.3 bits (129), Expect = 5e-07
Identities = 63/246 (25%), Positives = 105/246 (42%), Gaps = 28/246 (11%)
Query: 476 RMISVEKAKNEPAGKKLSDRKECEVKKEKLSSVDRHHSVEIKIEKTVIKKEEKIEKKE-- 533
R S EK+++ ++ +E E ++E+ +R E + E+ KK ++ E +E
Sbjct: 381 RSRSREKSRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDA 440
Query: 534 -EKKPEDIKKEEKD---QDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVKTTS 589
E++ + K EK+ Q+ LK + T+ + ER ++ + E K
Sbjct: 441 YERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAERE---EERRRE---MAKEAK 494
Query: 590 RSKERSSKSQDRKSESKEKRDILSF----DKIKEQRERERQRQREREIRETERRREREQR 645
R KE D + + K R D+ KE ER R+RE+E E
Sbjct: 495 RLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKE----------ELE 544
Query: 646 EREQRLEAFHERKEKARLQRERLQLECQRQRLERERMERERLERERMRVERERRKEQERI 705
E QRL A A LQ R++ E +R+R + + E E E E + E+E ++E+
Sbjct: 545 EIRQRLLAEGHPDPDAELQ--RMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPME 602
Query: 706 HREREE 711
E E
Sbjct: 603 EEEEPE 608
Score = 30.8 bits (68), Expect = 6.3
Identities = 16/46 (34%), Positives = 30/46 (65%), Gaps = 2/46 (4%)
Query: 509 DRHHSVEIKIEKTVIKKEEKIEKKEEKKPEDIKKEEKDQDE--LKP 552
+R +IK E ++EE+ ++KEEK+ E +++EE+ + + LKP
Sbjct: 570 ERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQKPCLKP 615
>gi|4503509 eukaryotic translation initiation factor 3, subunit 10
theta, 150/170kDa [Homo sapiens]
Length = 1382
Score = 96.7 bits (239), Expect = 9e-20
Identities = 115/461 (24%), Positives = 180/461 (39%), Gaps = 60/461 (13%)
Query: 481 EKAKNEPAGKKLSDRKECEVKKEKLSSVDRHHSVEIKIEKTVIKKEEKIEKKEEKKPEDI 540
E+ K + ++L K+ E+ + +D E+ + + K+ E++EK++++ E +
Sbjct: 629 EQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQLEKEKKELQERL 688
Query: 541 KKEEKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVKTTSRSKERSSKSQD 600
K +EK D + + +R MD + + + T +E++ + ++
Sbjct: 689 KNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEERITTMQLEREKALEHKN 748
Query: 601 RKSESKEKRDILSF-----------DKIKEQRER----------ERQRQREREIRET--- 636
R S E RD+ +K+K+ ER ER+RQR+ E R T
Sbjct: 749 RMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEERKRQRKEERRITYYR 808
Query: 637 ERRREREQREREQRLEAFHERKEKARLQRERLQLECQRQRLERERMERERLERERMRVER 696
E+ E ++R EQ L+ ER+ R +RE E Q + + E +ER++ +RE ER
Sbjct: 809 EKEEEEQRRAEEQMLKEREERERAERAKREEELREYQERVKKLEEVERKKRQRELEIEER 868
Query: 697 ERRKEQERIHREREELRRQQEQLRYEQERRPGRRPYDLDRRDDAYWPEGKRVAMEDRYRA 756
ERR+E+ER R L + R R R+ E +R E +R
Sbjct: 869 ERRREEER--------RLGDSSLSRKDSRWGDRDSEGTWRKGPEADSEWRRGPPEKEWRR 920
Query: 757 DFPRPDHRFHDFDHRDRGQYQDHAIDRREGSRPMMGDHRDGQHYGDDRHGHGGPPE---- 812
R + R H D + D DR RP D + DDR GP E
Sbjct: 921 GEGRDEDRSHRRDEERPRRLGDDE-DREPSLRP-DDDRVPRRGMDDDRGPRRGPEEDRFS 978
Query: 813 -RHGRDSRDGWGGYGSDKR----LSEGRGL------PPPPRGGRDWGEHNQRLEEHQARA 861
R D R W D+ E RG PPR G D + R +
Sbjct: 979 RRGADDDRPSWRNTDDDRPPRRIADEDRGNWRHADDDRPPRRGLDEDRGSWRTADEDRGP 1038
Query: 862 WQGAMD-----AGAASREHARW------QGGERGLSGPSGP 891
+G D G A E + W +G RGL GP
Sbjct: 1039 RRGMDDDRGPRRGGADDERSSWRNADDDRGPRRGLDDDRGP 1079
Score = 50.8 bits (120), Expect = 6e-06
Identities = 56/188 (29%), Positives = 88/188 (46%), Gaps = 25/188 (13%)
Query: 548 DELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVKTTSRSKERSSKSQDRKSESKE 607
D+ +PGP R V G R E+ ++S G P S + R +R K +DR ++ +E
Sbjct: 1162 DDSRPGPW-RPLVKPGGWREKEKA--REESWGPPRESRPSEEREWDRE-KERDRDNQDRE 1217
Query: 608 KRDILSFDKIKEQRERERQRQREREI-RETERRREREQR--EREQRLEAFHERKEKARLQ 664
+ D ++ ER+R RER++ RE RR R++ R E+ R R
Sbjct: 1218 END----------KDPERERDRERDVDREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDD 1267
Query: 665 RERLQLECQRQRLERERMERERLERERMRVERERRKEQERIHREREELRRQQEQLRYE-- 722
R+R +R ER+ R+ ER +R +R+RR R RE R+ + + +
Sbjct: 1268 RDR-----DDRRRERDD-RRDLRERRDLRDDRDRRGPPLRSEREEVSSWRRADDRKDDRV 1321
Query: 723 QERRPGRR 730
+ER P RR
Sbjct: 1322 EERDPPRR 1329
Score = 49.7 bits (117), Expect = 1e-05
Identities = 34/107 (31%), Positives = 59/107 (55%), Gaps = 6/107 (5%)
Query: 621 RERERQRQREREIRETERRREREQ-REREQRLEAFHERKEKARLQRERLQLECQRQRLER 679
+E+E Q Q R+E ++ R Q +E ER E +QRE+ +LE + L++
Sbjct: 544 QEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQREAELQK 603
Query: 680 ERMERERLERERMRVERERRKEQERIHREREELRRQQEQLRYEQERR 726
R + E ER+R E + R E+ERI +E E+++++ + R EQ ++
Sbjct: 604 VR----KAEEERLRQEAKER-EKERILQEHEQIKKKTVRERLEQIKK 645
Score = 49.3 bits (116), Expect = 2e-05
Identities = 60/207 (28%), Positives = 82/207 (39%), Gaps = 35/207 (16%)
Query: 683 ERERLERERMRVERERRKEQERIHREREELRRQQEQLRYEQERRPGR---RPYDLDR--- 736
E+E+ E RE R +ER +RE+ R + Q R E ++ P R R D+DR
Sbjct: 1180 EKEKAREESWGPPRESRPSEER-EWDREKERDRDNQDREENDKDPERERDRERDVDREDR 1238
Query: 737 ----RDDAYWPEGKRVAMEDRYRADFPRPDHRFHDFDHRDRGQYQDHAIDRREGSRPMMG 792
RD+ W G A E D R D R D R+R DRR
Sbjct: 1239 FRRPRDEGGWRRGP--AEESSSWRDSSRRDDRDRDDRRRERD-------DRR-------- 1281
Query: 793 DHRDGQHYGDDRHGHGGPPERHGRDSRDGW--GGYGSDKRLSE---GRGLPPPPRG-GRD 846
D R+ + DDR GPP R R+ W D R+ E R +PPP R+
Sbjct: 1282 DLRERRDLRDDRD-RRGPPLRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRE 1340
Query: 847 WGEHNQRLEEHQARAWQGAMDAGAASR 873
+R E + +W+ D + R
Sbjct: 1341 RDRDREREGEKEKASWRAEKDRESLRR 1367
Score = 41.6 bits (96), Expect = 0.004
Identities = 36/168 (21%), Positives = 84/168 (50%), Gaps = 29/168 (17%)
Query: 572 VVMDKSKGEPVISVKTTSRSKERSSKSQDRKSESKEKRDILSFDKIKEQRERERQRQRER 631
++ +K + + S++ + R+ +E+++ L + + QRE+E QRE
Sbjct: 542 ILQEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERL--ESLNIQREKEELEQREA 599
Query: 632 EIRETERRREREQREREQRLEAFHERKEKARLQRERLQLECQRQRLERERMERERL---- 687
E+++ R+ E+R R++ E +EK R+ +E Q+ +++ RER+E+ +
Sbjct: 600 ELQKV--RKAEEERLRQEAKE-----REKERILQEHEQI---KKKTVRERLEQIKKTELG 649
Query: 688 ----------ERERMRVERERRKEQERIHREREELRRQQEQLRYEQER 725
+ E + + K+ E++ +E++EL QE+L+ ++++
Sbjct: 650 AKAFKDIDIEDLEELDPDFIMAKQVEQLEKEKKEL---QERLKNQEKK 694
Score = 40.4 bits (93), Expect = 0.008
Identities = 41/142 (28%), Positives = 64/142 (45%), Gaps = 26/142 (18%)
Query: 623 RERQRQRE------REIRETERRREREQREREQRLEAFHERKEKARLQRERLQLECQRQR 676
RE+++ RE RE R +E R ++ER++ + E + +R+R + + R
Sbjct: 1179 REKEKAREESWGPPRESRPSEEREWDREKERDRDNQDREENDKDPERERDRERDVDREDR 1238
Query: 677 LERERME--------------RERLER-ERMRVERERRKEQERIHREREELR----RQQE 717
R R E R+ R +R R +R R ++ R RER +LR R+
Sbjct: 1239 FRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDLRERRDLRDDRDRRGP 1298
Query: 718 QLRYEQERRPGRRPYDLDRRDD 739
LR E+E R D DR+DD
Sbjct: 1299 PLRSEREEVSSWRRAD-DRKDD 1319
Score = 37.0 bits (84), Expect = 0.088
Identities = 39/184 (21%), Positives = 73/184 (39%), Gaps = 23/184 (12%)
Query: 481 EKAKNEPAGKKLSDRKECEVKKEKLSSVDRHHSVEIKIEKTVIKKEEKIEKKEEKKPEDI 540
EKA+ E G R E + ++ DR + + +K E + +++ + ED
Sbjct: 1182 EKAREESWGPPRESRPSEEREWDREKERDRDNQDREENDKD---PERERDRERDVDREDR 1238
Query: 541 KKEEKDQDELKPGPTNRSRVTKSGSRG------------------MERTVVMDKS--KGE 580
+ +D+ + GP S + SR ER + D +G
Sbjct: 1239 FRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDLRERRDLRDDRDRRGP 1298
Query: 581 PVISVKTTSRSKERSSKSQDRKSESKEKRDILSFDKIKEQRERERQRQREREIRETERRR 640
P+ S + S R+ +D + E ++ + + RER+R R+RE E + R
Sbjct: 1299 PLRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERDRDREREGEKEKASWRA 1358
Query: 641 EREQ 644
E+++
Sbjct: 1359 EKDR 1362
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 95.1 bits (235), Expect = 3e-19
Identities = 62/204 (30%), Positives = 115/204 (56%), Gaps = 18/204 (8%)
Query: 524 KKEEKIEKKEEKKPEDIKKEEKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVI 583
+KE K E++ E+K E ++E++ ++ K R + K G R E ++ K
Sbjct: 48 RKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEER---ERKKR---- 100
Query: 584 SVKTTSRSKERSSKSQDRKSESKEKRDILSFDKIKEQRE-RERQRQREREIRETERRRER 642
+ +KE K + +K E KE+ K +E++E R+R+ ++ERE ++ ER +ER
Sbjct: 101 --RREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKER 158
Query: 643 EQREREQRL-----EAFHERKEKARLQRERLQLECQRQRLERERMERERLERERMRVE-- 695
E++ER++R E ERKEK R +R++ + + ++ ERER ER ++ER + E
Sbjct: 159 ERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEER 218
Query: 696 -RERRKEQERIHREREELRRQQEQ 718
+ER+K+++ RE+E +R++++
Sbjct: 219 KKERQKDRQTNWREKERGKRERKE 242
Score = 83.6 bits (205), Expect = 8e-16
Identities = 62/201 (30%), Positives = 111/201 (55%), Gaps = 27/201 (13%)
Query: 539 DIKKEEKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVKTTSRSKERSSKS 598
+I++ E++ + K G R K R E+ K + E K R + + K
Sbjct: 37 EIREREREIETRKEGKKERESERKKERREREKR----KRERE-----KERKRERGKKEKK 87
Query: 599 QDRKSESKEKRDILSFDKIKEQRERERQRQRE--------REIRETERRREREQREREQR 650
+RK E +E++ + KE E+E+++++E +E +E ER+ ER++ ER++R
Sbjct: 88 GERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKER 147
Query: 651 ----LEAFHERKEKARLQRERLQL-ECQRQRLERERMERERLERERMRVERERRKEQER- 704
E ER+ K R +RER Q+ E + +R E+ER ER++ ER R +ER+KE+ER
Sbjct: 148 ERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNR----KERKKERERK 203
Query: 705 IHREREELRRQQEQLRYEQER 725
RER++ R+++E+ + E+++
Sbjct: 204 ERRERKKERKKKEERKKERQK 224
Score = 82.4 bits (202), Expect = 2e-15
Identities = 51/146 (34%), Positives = 90/146 (61%), Gaps = 14/146 (9%)
Query: 594 RSSKSQDRKSESKEKRDILSFDKIKEQRERERQRQREREIRETERRREREQREREQRL-- 651
R ++R+SE K++R ++ K +RERE++R+RER +E + R++E+RER++R
Sbjct: 48 RKEGKKERESERKKERR----EREKRKREREKERKRERGKKEKKGERKKEERERKKRRRE 103
Query: 652 ------EAFHERKEKARLQRERLQLECQRQRLERERMERERLERERMRVERERRKE-QER 704
E +RK+K + +R R E + + + ER ER ERER + ERE+ +E +ER
Sbjct: 104 KENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKER 163
Query: 705 IHREREELRRQQEQLRYEQERRPGRR 730
RER+++ ++E+ R E+ER+ ++
Sbjct: 164 KKRERKQVGEKEEE-RKEKERKERKK 188
Score = 80.9 bits (198), Expect = 5e-15
Identities = 62/233 (26%), Positives = 119/233 (51%), Gaps = 27/233 (11%)
Query: 589 SRSKERSSKSQDRKSESKEKRDILSFDKIKEQRERERQRQREREIRETERRREREQRERE 648
S +ER + + RK KE+ ++ KE+RERE+ R+RE RE ER+RER ++E++
Sbjct: 36 SEIREREREIETRKEGKKERES----ERKKERREREK-RKRE---REKERKRERGKKEKK 87
Query: 649 QRLEAFHERKEKARLQRERLQLECQRQRLERERMERERLERE-RMRVERERRKEQERIHR 707
+ ++K R ++E + E + +R ++E+ ER R +E + R +E RK +ER R
Sbjct: 88 GERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKER 147
Query: 708 EREELRRQQEQLRYEQERRPGRRPYDLDRRDDAYWPEGKRVAMEDRYRADFPRPDHRFHD 767
ER++ R++E+ R E+++R E K+V ++ R + R + + +
Sbjct: 148 ERKKEEREKERERKERKKR-----------------ERKQVGEKEEERKEKERKERKKRE 190
Query: 768 FDHRDRGQYQDHAIDRREGSRPMMGDHRDGQHYGDDRHGHGGPPERHGRDSRD 820
+ ++R + ++ +RRE + + DR + ER R+ ++
Sbjct: 191 RNRKERKKERERK-ERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKE 242
Score = 65.5 bits (158), Expect = 2e-10
Identities = 57/227 (25%), Positives = 110/227 (48%), Gaps = 20/227 (8%)
Query: 455 MSTSDEATKCISHLHRTELHGRMISVE---KAKNEPAGKKLSDRKECEVKKEKLSSVDRH 511
+S S + C ++E+ R +E + K E ++ +R+E E +K + +R
Sbjct: 20 VSCSHISKPCTQPGWQSEIREREREIETRKEGKKERESERKKERREREKRKREREK-ERK 78
Query: 512 HSVEIKIEKTVIKKEEKIEKKEEKKPEDIKKEEKDQDELKPGPTNRSRVTKSGS------ 565
K +K KKEE+ KK ++ E+ + EEK++ + K R R +K G
Sbjct: 79 RERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKE-KKERGRTSKEGKERERKE 137
Query: 566 -RGMERTVVMDKSKGEPVISVKTTSRSKER----SSKSQDRKSESKEKRDILSFDKIKEQ 620
R E ++ K E + R K K ++RK + +++R ++ + +
Sbjct: 138 ERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERK 197
Query: 621 RERERQRQREREIRETERRREREQREREQRLEAFHERKEKARLQRER 667
+ERER+ +RER+ + R+++E+R++E++ + +EK R +RER
Sbjct: 198 KERERKERRERK----KERKKKEERKKERQKDRQTNWREKERGKRER 240
Score = 49.7 bits (117), Expect = 1e-05
Identities = 43/168 (25%), Positives = 81/168 (48%), Gaps = 39/168 (23%)
Query: 481 EKAKNEPAGKKLSDRKECEVKKEKLSSVDRHHSVEIKIEKTVIKKEEKIEKKEEKKPEDI 540
+K + + G+ + KE E +KE+ +R K E+ ++ ++ +K+E K+ +
Sbjct: 116 KKKEKKERGRTSKEGKERE-RKEERKREERKERERKKEEREKERERKERKKRERKQVGE- 173
Query: 541 KKEEKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVKTTSRSKERSSKSQD 600
K+EE+ + E K ER + +ER+ K +
Sbjct: 174 KEEERKEKERK-----------------ER-------------------KKRERNRKERK 197
Query: 601 RKSESKEKRDILSFDKIKEQRERERQRQREREIRETER-RREREQRER 647
++ E KE+R+ K KE+R++ERQ+ R+ RE ER +RER++R++
Sbjct: 198 KERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 92.0 bits (227), Expect = 2e-18
Identities = 73/253 (28%), Positives = 133/253 (52%), Gaps = 40/253 (15%)
Query: 490 KKLSDRKECEVKKEKLSSVDRHHSVEIKIEKTVIKKEEKIEKKEEKKPEDIKKEEKDQDE 549
K +S R ++ E L V H I K ++E E+K+E++ + +K E++++
Sbjct: 3 KAISSRAAVKLNTE-LQMVSCSH-----ISKPCTQRES--ERKKERREREKRKREREKER 54
Query: 550 LKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVKTTSRSKERSSKSQDRKSESKEKR 609
+ + K RG ER + KER + ++R+ + + KR
Sbjct: 55 KRERGKKEKKKRKKRERGKERE-----------------RKRKEREKQRKERREKERRKR 97
Query: 610 DILSFDKIKEQRERERQRQREREIRETERRREREQREREQRLEAFHERKEKARLQRERLQ 669
K K++RER+++ +RER+ ++ + RERE ++R +R RK+K R +R+R
Sbjct: 98 K-----KEKKKRERKQRGRRERKKKKERKERERENKQRRERKRK-KRRKKKRRKERKR-- 149
Query: 670 LECQRQRLERERMERERLERE--RMRVERERRKEQERIHREREELRRQQEQLRYEQERRP 727
E +R + ER+R +R++ ERE R R +ER+KE+ER R RE + ++++ R ++ER+
Sbjct: 150 -EKERGKRERKRKKRKKEEREKKRERNRKERKKERERKER-RERKKERKKERRKKKERKK 207
Query: 728 GRRPYDLDRRDDA 740
R+ DR+ D+
Sbjct: 208 DRK---TDRQTDS 217
Score = 73.6 bits (179), Expect = 8e-13
Identities = 53/173 (30%), Positives = 99/173 (57%), Gaps = 7/173 (4%)
Query: 618 KEQRERERQRQREREIRETERRREREQREREQRLEAFHER-KEKARLQRERLQLECQRQR 676
+ +R++ER+ +RE+ RE E+ R+RE+ ++E++ ER KE+ R ++ER + +R+
Sbjct: 33 ESERKKERR-EREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERRE 91
Query: 677 LERERMERERLERER-MRVERERRKEQERIHREREELRRQQEQLRYEQERRPGRRPYDLD 735
ER + ++E+ +RER R RER+K++ER RERE +R++ R ++RR +R +
Sbjct: 92 KERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRE---RKRKKRRKKKRRKERK 148
Query: 736 RRDDAYWPEGKRVAMEDRYRADFPRPDHRFHDFDHRDRGQYQDHAIDRREGSR 788
R + E KR + R + R +R R+R + ++ +R++ R
Sbjct: 149 REKERGKRERKRKKRKKEER-EKKRERNRKERKKERERKERRERKKERKKERR 200
Score = 65.5 bits (158), Expect = 2e-10
Identities = 51/182 (28%), Positives = 89/182 (48%), Gaps = 17/182 (9%)
Query: 470 RTELHGRMISVEKAKNEPAGKKLSDRKECEVKKEKLSSVDRHHSVEIKIEKTVIKKEEKI 529
R E R EK + GKK +++ K+E+ +R K K +KE +
Sbjct: 40 RREREKRKREREKERKRERGKKEKKKRK---KRERGKERERKRKEREKQRKERREKERRK 96
Query: 530 EKKEEKKPEDIKKEEKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVKTTS 589
KKE+KK E ++++ + E K + R ++ R + K K K
Sbjct: 97 RKKEKKKRE---RKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRR-----KERK 148
Query: 590 RSKERSSKSQDRKSESKEKRDILSFDKIKEQRERERQRQRER-EIRETERRREREQRERE 648
R KER + + RK KE+R+ K +E+ +ER+++RER E RE ++ R++E+R+++
Sbjct: 149 REKERGKRERKRKKRKKEERE-----KKRERNRKERKKERERKERRERKKERKKERRKKK 203
Query: 649 QR 650
+R
Sbjct: 204 ER 205
Score = 45.4 bits (106), Expect = 2e-04
Identities = 41/187 (21%), Positives = 87/187 (46%), Gaps = 28/187 (14%)
Query: 634 RETERRREREQREREQRLEAFHERKEKARLQRERLQLECQRQRLERERMERERLERERMR 693
RE+ER++ER +RE+ +R +EK R +RER ++E+ +R++
Sbjct: 32 RESERKKERREREKRKR------EREKER---------------KRERGKKEKKKRKK-- 68
Query: 694 VERERRKEQERIHREREELRRQQEQLRYEQERRPGRRPYDLDRRDDAYWPEGKRVAMEDR 753
RER KE+ER +R+E +Q+++ R ++ R+ + +R+ K+ ++R
Sbjct: 69 --RERGKERER---KRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKER 123
Query: 754 YRADFPRPDHRFHDFDHRDRGQYQDHAIDRREGSRPMMGDHRDGQHYGDDRHGHGGPPER 813
R + R + + + R + + +R + R ++ + +R+ ER
Sbjct: 124 ERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKER 183
Query: 814 HGRDSRD 820
++ R+
Sbjct: 184 ERKERRE 190
Score = 42.7 bits (99), Expect = 0.002
Identities = 42/161 (26%), Positives = 72/161 (44%), Gaps = 14/161 (8%)
Query: 484 KNEPAGKKLSDRKECEVKKEKLSSVDRHHSVEIKIEKTVIKKEEKIEKKEEKKPEDIKKE 543
K + K+ +R+E E +K K R + E+ KK+E+ E++ E K +K
Sbjct: 78 KRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERK--KKKERKERERENKQRRERKR 135
Query: 544 EKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVKTTSRSKERSSKSQ-DRK 602
+K + K R R + G R +R K + E R KER K + +RK
Sbjct: 136 KKRRK--KKRRKERKREKERGKRERKRKK-RKKEEREKKRERNRKERKKERERKERRERK 192
Query: 603 SESKEKRDILSFDKIKEQRERERQRQREREIRETERRRERE 643
E K++R ++++ER++ R+ +R+ R RE
Sbjct: 193 KERKKER--------RKKKERKKDRKTDRQTDSQVFRPLRE 225
Score = 31.6 bits (70), Expect = 3.7
Identities = 25/87 (28%), Positives = 43/87 (49%), Gaps = 4/87 (4%)
Query: 481 EKAKNEPAGKKLSDRKECEVKKEKLSSVDRHHSVEIKIEKTVIKKEEKIEKKEEKKPEDI 540
EK + + K+ +KE KK + + +R E K E+ KKE K E++++K+ +
Sbjct: 150 EKERGKRERKRKKRKKEEREKKRERNRKERKKERERK-ERRERKKERKKERRKKKERKKD 208
Query: 541 KKEEKDQDELKPGPTNRS---RVTKSG 564
+K ++ D P S RVT +G
Sbjct: 209 RKTDRQTDSQVFRPLRESAFNRVTVTG 235
>gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]
Length = 202
Score = 90.1 bits (222), Expect = 9e-18
Identities = 64/206 (31%), Positives = 110/206 (53%), Gaps = 16/206 (7%)
Query: 531 KKEEKKPEDIKKE---EKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVKT 587
++E K+ D KE E+D+ + T R + R ER D+ K +
Sbjct: 4 QRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERD 63
Query: 588 TSRSKERSSKSQDRKSESKEKRDILSFDKIKEQRERERQRQREREIRETERRREREQ--- 644
R +ER + +R++E + +R K + RER++ R RER+ RET+R RER +
Sbjct: 64 RQRQRERET---ERETERQRERQRQRERKRQTDRERDKDRDRERK-RETDRNRERNRKGG 119
Query: 645 REREQRLEAFHERKEKARLQRERLQLECQRQRLERERMERER---LERERMRVERERRKE 701
RER+++ E +R+ + + QRER E QRQR + +RER ERE + ER++ ++
Sbjct: 120 RERDKQTERERDRERERQRQRER---ERQRQRERKRETDRERQRWAEREERKKERKKERK 176
Query: 702 QERIHREREELRRQQEQLRYEQERRP 727
+ER +++EE RR+ ++ ++ + P
Sbjct: 177 KERKEKKKEEKRREDKKRKWGEGISP 202
Score = 77.8 bits (190), Expect = 4e-14
Identities = 66/200 (33%), Positives = 106/200 (53%), Gaps = 13/200 (6%)
Query: 566 RGMERTVVMDKSKGEPVISVKTTSRSKERSSKSQDRKSESKEKRDILSFDKIKE---QRE 622
R ER D+ K + R + +++ R+ + +RD + D+ KE Q+E
Sbjct: 3 RQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQT-DREKERERQKE 61
Query: 623 RERQRQREREI-RETERRREREQREREQRLEAFHERKEKARLQRERLQLECQRQRLERER 681
R+RQRQRERE RETER+RER QR+RE++ + ER +K R + + + + R+R +
Sbjct: 62 RDRQRQRERETERETERQRER-QRQRERKRQTDRER-DKDRDRERKRETDRNRERNRKGG 119
Query: 682 MERER-LERERMRVERERRKEQERIHREREELRRQQEQLRYEQERRPGRRPYDLDRRDDA 740
ER++ ERER R ERER++++ER + + E +R+ ++ R R R+ R
Sbjct: 120 RERDKQTERERDR-ERERQRQRERERQRQRERKRETDRERQRWAEREERK----KERKKE 174
Query: 741 YWPEGKRVAMEDRYRADFPR 760
E K E++ R D R
Sbjct: 175 RKKERKEKKKEEKRREDKKR 194
Score = 70.1 bits (170), Expect = 9e-12
Identities = 52/186 (27%), Positives = 102/186 (54%), Gaps = 12/186 (6%)
Query: 490 KKLSDRKECEVKKEKLSSVDRHHSVEIKIEKTVIKKEEKIEKKEEKKPEDIKKEEKDQDE 549
K+ +DR + E ++E+ +R + E + + + +++ +++ E +++E+D+
Sbjct: 8 KRETDRGK-ETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQR 66
Query: 550 LKPGPTNRS---RVTKSGSRGMERTVVMDKSKGEPVISVKTTSRSKERSSK-SQDRKSES 605
+ T R + + R +R ++ K + T R++ER+ K ++R ++
Sbjct: 67 QRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQT 126
Query: 606 KEKRDILSFDKIKEQRERERQRQREREIRETERRR----EREQREREQRLEAFHERKEKA 661
+ +RD + + QRERERQRQRER+ RET+R R ERE+R++E++ E ERKEK
Sbjct: 127 ERERD--RERERQRQRERERQRQRERK-RETDRERQRWAEREERKKERKKERKKERKEKK 183
Query: 662 RLQRER 667
+ ++ R
Sbjct: 184 KEEKRR 189
Score = 67.4 bits (163), Expect = 6e-11
Identities = 51/172 (29%), Positives = 91/172 (52%), Gaps = 10/172 (5%)
Query: 619 EQRERERQRQREREIRETERRREREQREREQRLEAFHERKEKARLQRERLQLECQRQRLE 678
++ ERER RQRERE +TER QR+R + + +R+++ Q+ER + QR+R
Sbjct: 15 KETERERDRQRERE-NQTERENRHRQRDRHRERDRQTDREKERERQKER-DRQRQRERET 72
Query: 679 RERMERERLERERMRVERERRKEQERIHREREELRRQQEQLRYEQERRPGRRPYDLDRRD 738
ER+R ER+R R ER+R+ ++ER ++R+ R+++ E+ R+ GR R+
Sbjct: 73 ERETERQR-ERQRQR-ERKRQTDRER-DKDRDRERKRETDRNRERNRKGGRERDKQTERE 129
Query: 739 DAYWPEGKRVAMEDRYR-----ADFPRPDHRFHDFDHRDRGQYQDHAIDRRE 785
E +R +R R + R R+ + + R + + ++ +R+E
Sbjct: 130 RDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKE 181
Score = 62.0 bits (149), Expect = 3e-09
Identities = 39/117 (33%), Positives = 71/117 (60%), Gaps = 6/117 (5%)
Query: 620 QRERERQRQREREIRETERRREREQREREQRLEAFHERKEKARLQRERLQLECQRQRLER 679
+R+RER+R+ +R +ETER R+R QRERE + E + +++ R + Q + +++R +
Sbjct: 2 ERQRERKRETDRG-KETERERDR-QRERENQTERENRHRQRDRHRERDRQTDREKERERQ 59
Query: 680 ERMERERLERERMRVERERRKEQERIHREREELRRQQEQLRYEQERRPGRRPYDLDR 736
+ +R+R +RER E ER E++R + + E +RQ ++ R + R +R D +R
Sbjct: 60 KERDRQR-QRER---ETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNR 112
Score = 48.9 bits (115), Expect = 2e-05
Identities = 35/161 (21%), Positives = 78/161 (48%), Gaps = 16/161 (9%)
Query: 481 EKAKNEPAGKKLSDRKECEVKKEKLSSVDRHHSVEIKIEKTVIKKEEKIEKKEEKKPEDI 540
++ ++ ++ KE E +KE+ DR E + E+ ++ E+ ++E K+ D
Sbjct: 39 QRDRHRERDRQTDREKERERQKER----DRQRQRERETERETERQRERQRQRERKRQTDR 94
Query: 541 KKE-EKDQDELKPGPTNRSRVTKSG-----------SRGMERTVVMDKSKGEPVISVKTT 588
+++ ++D++ + NR R K G R ER ++ + + T
Sbjct: 95 ERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRET 154
Query: 589 SRSKERSSKSQDRKSESKEKRDILSFDKIKEQRERERQRQR 629
R ++R ++ ++RK E K++R +K KE++ RE ++++
Sbjct: 155 DRERQRWAEREERKKERKKERKKERKEKKKEEKRREDKKRK 195
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 89.7 bits (221), Expect = 1e-17
Identities = 66/280 (23%), Positives = 146/280 (52%), Gaps = 17/280 (6%)
Query: 490 KKLSDRKECEVKKEKLSSVDRHHSVEIKI---EKTVIKKEEKIEKKEEK---KPEDIKKE 543
+K+ +++E ++EK+ ++ E K+ E+ + ++EEKI ++E+K + E I ++
Sbjct: 404 EKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQ 463
Query: 544 EKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVKTTSRS---KERSSKSQD 600
EK ++E K + E + E ++ +E + Q+
Sbjct: 464 EKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQE 523
Query: 601 RKSESKEKRDILSFDKIKEQRE--RERQRQRERE-IRETERRREREQREREQRLEAFHER 657
K +E++ +KI+EQ E RE ++ E+E I E E+R+E+E + Q E E+
Sbjct: 524 EKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQE-EKIREQ 582
Query: 658 KEKARLQRERLQLECQRQRLERERM----ERERLERERMRVERERRKEQERIHREREELR 713
+EK Q E+++ + ++++ + E+M E+ R + E+++ + E+ +EQE RE+EE+
Sbjct: 583 EEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMT 642
Query: 714 RQQEQLRYEQERRPGRRPYDLDRRDDAYWPEGKRVAMEDR 753
++QE+ EQE + + + +++ W + +++ +++
Sbjct: 643 QEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEK 682
Score = 89.4 bits (220), Expect = 1e-17
Identities = 73/283 (25%), Positives = 143/283 (50%), Gaps = 21/283 (7%)
Query: 519 EKTVIKKEEKIEKKEEK---KPEDIKKEEKDQDELKPGPTNRSRVTKSGSRGMERTVVMD 575
E+ + ++EEKI++ EEK + E I+++E+ E + + + M R M
Sbjct: 299 EEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMM 358
Query: 576 KSKGEPVISVKTTSRSKERSSKSQDRKSESKEKRDILSFDKIKEQ---RERERQRQRERE 632
K E + + KE + Q+ KE++ +K+ EQ RE+E +RQ E +
Sbjct: 359 WEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEK 418
Query: 633 IRETERRREREQREREQRLEAFHERKEKARLQRERL-QLECQRQRLERERMERERLERER 691
IRE E+R+E+E + Q E E++EK R Q +++ + E + E+ R E +R E+E
Sbjct: 419 IREQEKRQEQEAKMWRQE-EKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEE 477
Query: 692 MRVERERRKEQERIHREREELRRQQEQLR------YEQERRPGRRPYDLDRRDDAYWPEG 745
M + E+ EQE I R++E++ Q+E++R + QE + + + +++ W +
Sbjct: 478 MWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQE 537
Query: 746 KRVAMEDRYRADFPRPDHRFHDFD---HRDRGQYQDHAIDRRE 785
+++ R + + R + + H+ + ++ Q Q+ + R+E
Sbjct: 538 EKI----REQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQE 576
Score = 86.7 bits (213), Expect = 1e-16
Identities = 68/244 (27%), Positives = 131/244 (53%), Gaps = 29/244 (11%)
Query: 490 KKLSDRKECEVKKEKLSSVDRHHSVEIKI---EKTVIKKEEKIEKKEEKKPEDIKKEEKD 546
+K+ +++E +KEK+ H E KI E+ V ++EEKI ++EEK E +K +
Sbjct: 483 EKIHEQEEIWRQKEKM------HEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQ 536
Query: 547 QDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVKTTSRSKERSSKSQDRKSESK 606
+++++ + + + + E+ + ++ K + +E Q+ K +
Sbjct: 537 EEKIR----EQEEMWREEEKMHEQEKIWEEEKRQ----------EQEDKMWRQEEKIREQ 582
Query: 607 EKRDILSFDKIKEQRERERQRQREREIRETERRREREQREREQRLEAFHERKEKARLQRE 666
E++ +KI+EQ E+ RQ Q E+ ++ E+ RE+E++ +EQ E E++EK R Q E
Sbjct: 583 EEKVWRQEEKIREQEEK-RQEQEEKMWKQEEKIREQEEKIQEQE-EKIREQEEKIREQEE 640
Query: 667 RLQLECQRQRLERERM----ERERLERERMRVERERRKEQERIHREREELRRQQEQLRYE 722
Q + ++ + E+M E+ + + E M + E+ +EQE+ RE+EE R+QE++ E
Sbjct: 641 MTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQE 700
Query: 723 QERR 726
QE +
Sbjct: 701 QEEK 704
Score = 80.1 bits (196), Expect = 9e-15
Identities = 71/280 (25%), Positives = 144/280 (51%), Gaps = 32/280 (11%)
Query: 495 RKECEVKKEKLSSVDRHHSVEIKIEKTVIKKEEKIEKKEEK--KPEDI--KKEEKDQDEL 550
R++ E+ EK + R + + E+ + ++EE + +KEEK + E++ +KEEK + EL
Sbjct: 338 RRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIR-EL 396
Query: 551 KPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVKTTSRSKERSSKSQDRKSESKEKRD 610
+ + ++ + + E + ++ K + + +E + Q+ K +EK+
Sbjct: 397 EEKMHEQEKIREQEEKRQEEEKIREQEKRQ---EQEAKMWRQEEKIREQEEKIREQEKKM 453
Query: 611 ILSFDKIKEQ---RERERQRQREREIRETERRREREQREREQRLEAFHERKEKARLQRER 667
+KI EQ RE E+++++E R+ E+ E+E+ R++ E HE++EK R Q E+
Sbjct: 454 WRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQK--EKMHEQEEKIRKQEEK 511
Query: 668 L--QLECQRQRLERERMERERL--------ERERMRVERERRKEQERIHREREELRRQQE 717
+ Q E R++ E+ R + E++ E+E M E E+ EQE+I EE R++QE
Sbjct: 512 VWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIW--EEEKRQEQE 569
Query: 718 QLRYEQERRPGRRPYDLDRRDDAYWPEGKRVAMEDRYRAD 757
+ QE + + +++ W + +++ ++ R +
Sbjct: 570 DKMWRQEEK-------IREQEEKVWRQEEKIREQEEKRQE 602
Score = 74.7 bits (182), Expect = 4e-13
Identities = 79/329 (24%), Positives = 163/329 (49%), Gaps = 39/329 (11%)
Query: 460 EATKCISHLHRT-ELHGRMISVEKAKNEPAG-KKLSDRKECEVKKEKLSSVDRHHSVEIK 517
EA IS LH + + G + E+A + A KK +DR E+ KE+ ++ ++
Sbjct: 159 EARDLISRLHDSWKFAGEL---EQALSAVATQKKKADRYIEELTKER-------DALSLE 208
Query: 518 IEKTVIKKEEKIEKKEEKKPEDIKKEEKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKS 577
+ + I EE +++K K E ++ E ++ E++ R + + + + ++
Sbjct: 209 LYRNTITDEE-LKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEA 267
Query: 578 ----KGEPVISVKTTSRSKE-----RSSKSQDRKSESKEKRDILSFDKIKEQRERER-QR 627
K +S K ++ +E R ++ Q+ K +E++ +KI+EQ E+ R Q
Sbjct: 268 DHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQE 327
Query: 628 QREREIRETERRREREQREREQRL----EAFHERKEKARLQRERLQLECQRQRLERERM- 682
++ RE E RR+E E+E+++ E E++EK R Q E + + ++ R + E M
Sbjct: 328 EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMW 387
Query: 683 ---------ERERLERERMRVERERRKEQERIHREREELRRQQEQLRYEQERRPGRRPYD 733
E + E+E++R + E+R+E+E+I RE+E+ R++QE + QE + +
Sbjct: 388 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKI-REQEK-RQEQEAKMWRQEEKIREQEEK 445
Query: 734 LDRRDDAYWPEGKRVAMEDRYRADFPRPD 762
+ ++ W + +++ +++ R + R +
Sbjct: 446 IREQEKKMWRQEEKIHEQEKIREEEKRQE 474
Score = 67.8 bits (164), Expect = 5e-11
Identities = 55/211 (26%), Positives = 110/211 (52%), Gaps = 23/211 (10%)
Query: 519 EKTVIKKEEKI---EKKEEKKPEDIKKEEKDQDELKPGPTNRSRVTKSGSRGMERTVVMD 575
E+ + ++EKI EK++E++ + ++EEK +++ + ++ + + E+ M
Sbjct: 549 EEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMW 608
Query: 576 KSKGEPVISVKTTSRSKERSSKSQDRKSESKEKRDILSFDKIKEQRERERQRQREREIRE 635
K + + R +E + Q+ K +E +KI+EQ E Q Q E+ +
Sbjct: 609 KQEEK--------IREQEEKIQEQEEKIREQE-------EKIREQEEM-TQEQEEKMGEQ 652
Query: 636 TERRREREQREREQRLEAFHERKEKARLQRERLQLECQRQRLERERMERERLERERMRVE 695
E+ E+E++ +EQ E ++EK R Q ++++ + ++ R + E M+ + E+M +
Sbjct: 653 EEKMCEQEEKMQEQE-ETMWRQEEKIREQEKKIREQEEKIREQEEMMQE---QEEKMWEQ 708
Query: 696 RERRKEQERIHREREELRRQQEQLRYEQERR 726
E+ EQE +E+EE R+QE+ +EQE R
Sbjct: 709 EEKMCEQEEKMQEQEEKMRRQEEKMWEQEVR 739
Score = 67.8 bits (164), Expect = 5e-11
Identities = 56/223 (25%), Positives = 117/223 (52%), Gaps = 28/223 (12%)
Query: 490 KKLSDRKECEVKKEKLSSVDRHHSVEIKI---EKTVIKKEEKIEKKEEKKPEDIKKEEKD 546
+K+ ++++ ++++ D+ E KI E+ V ++EEKI ++EEK+ E +K K
Sbjct: 551 EKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQ 610
Query: 547 QDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVKTTSRSKERSSKSQDRKSESK 606
++++ R E + + + E + + R +E ++ Q+ K +
Sbjct: 611 EEKI---------------REQEEKI---QEQEEKIREQEEKIREQEEMTQEQEEKMGEQ 652
Query: 607 EKRDILSFDKIKEQRERERQRQREREIRETERR-REREQREREQRLEAFHERKEKARLQR 665
E++ +K++EQ E ++E +IRE E++ RE+E++ REQ E E++EK Q
Sbjct: 653 EEKMCEQEEKMQEQEET--MWRQEEKIREQEKKIREQEEKIREQE-EMMQEQEEKMWEQE 709
Query: 666 ERLQLECQRQRLERERMERERLERERMRVERERRKEQERIHRE 708
E++ C+++ +E+ E+ R + E+M + R ++QE +E
Sbjct: 710 EKM---CEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 749
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 89.7 bits (221), Expect = 1e-17
Identities = 66/219 (30%), Positives = 116/219 (52%), Gaps = 20/219 (9%)
Query: 523 IKKEEKIEKKEEKKPEDIKKEEKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPV 582
++++E+ E+ +K E+ K+ ++ +LK R + + ER M + K + +
Sbjct: 545 LRRKEEAEQLRRQKVEEDKRRRLEEVKLK-----REERLRKVLQARERVEQMKEEKKKQI 599
Query: 583 ------ISVKTTSRSKERSSKSQ-DRKSESKEKRDILSFDKIKEQRERERQRQREREIRE 635
I KT +ER ++ + +K+ +K+ ++ + K +E+ R R Q+E E R
Sbjct: 600 EQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERR 659
Query: 636 TERRREREQREREQRLEAFHERKEKA--RLQRERLQLECQRQRLERERMERERLERERMR 693
+ ++++ E ++RL E K A R Q R Q +++R E+ER E+ER E+ER
Sbjct: 660 HQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQL 719
Query: 694 VERERRKEQERIHRERE------ELRRQQEQLRYEQERR 726
E+ERR+EQER+ ERE LR Q+EQL+ E E +
Sbjct: 720 AEQERRREQERLQAERELQEREKALRLQKEQLQRELEEK 758
Score = 88.2 bits (217), Expect = 3e-17
Identities = 71/250 (28%), Positives = 132/250 (52%), Gaps = 23/250 (9%)
Query: 480 VEKAKNEPAGKKLSDRKECEVKKEKLSSVDRHHSVEIKIEKT-----VIKKEEKIEKKEE 534
VEK + + + E +++++K+ R E+K+++ V++ E++E+ +E
Sbjct: 535 VEKERQRLENLRRKEEAE-QLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKE 593
Query: 535 KKPEDIKK-----EEKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVKTTS 589
+K + I++ +EK + + K+ ++ ME K + E
Sbjct: 594 EKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQ 653
Query: 590 RSKERSSKS--QDRKSESKEK-RDILSFDKIKEQRERER--QRQREREIRETERRREREQ 644
+ER + Q +K E +E+ R ++ EQRE+ER Q +RE+E RE E RRE+E+
Sbjct: 654 EEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQE-RREQER 712
Query: 645 REREQRLEAFHERKEKARLQRER-LQ-----LECQRQRLERERMERERLERERMRVERER 698
RE+E++L R+E+ RLQ ER LQ L Q+++L+RE E+++ E ++ ER+
Sbjct: 713 REQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQL 772
Query: 699 RKEQERIHRE 708
++EQE+ +E
Sbjct: 773 QEEQEKKAKE 782
Score = 54.3 bits (129), Expect = 5e-07
Identities = 49/213 (23%), Positives = 95/213 (44%), Gaps = 34/213 (15%)
Query: 592 KERSSKSQDRKSESKEKRDILSFDKIKEQRERERQRQREREIRETERRREREQREREQRL 651
KER R+ E E+ ++ Q+ E +R+R E++ R R+ + +R+
Sbjct: 537 KERQRLENLRRKEEAEQ--------LRRQKVEEDKRRRLEEVKLKREERLRKVLQARERV 588
Query: 652 EAFHERKEKARLQRERLQLECQRQRLERERMERERLERE----RMRVERERRKEQERIHR 707
E E K+K +++++ Q++ + ++ + ER+ E+ +++ +M RRK++E R
Sbjct: 589 EQMKEEKKK-QIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARR 647
Query: 708 ER-----EELRRQQEQLRYEQERRPGRRPYDLDRRDDAYWPEGKRVAMEDRYRADFPRPD 762
R EE RR QE L+ ++E E R A E + A+ +
Sbjct: 648 LRWLQQEEEERRHQELLQKKKEEE----------------QERLRKAAEAKRLAEQREQE 691
Query: 763 HRFHDFDHRDRGQYQDHAIDRREGSRPMMGDHR 795
R + ++R + + +RRE R + R
Sbjct: 692 RREQERREQERREQERREQERREQERQLAEQER 724
Score = 49.7 bits (117), Expect = 1e-05
Identities = 43/185 (23%), Positives = 94/185 (50%), Gaps = 23/185 (12%)
Query: 478 ISVEKAKNEPAGKKLSDRKECEVKKEKLSSVDRHHSVEIKIEKTVIKKEEKIEKKEEKKP 537
++ EKAK + A KK+ +E E ++++ R ++ + E+ + +E ++KK+E++
Sbjct: 618 LAEEKAKKKAAAKKM---EEVEARRKQEEEARRLRWLQQEEEER--RHQELLQKKKEEEQ 672
Query: 538 EDIKKEEKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVKTTSRSKERSSK 597
E ++K E K R + + R + ++ + E R +ER
Sbjct: 673 ERLRKAA----EAKRLAEQREQERREQERREQERREQERREQE--------RREQERQLA 720
Query: 598 SQDRKSESKEKRDILSFDKIKEQRERERQRQREREIRETERRREREQRER--EQRLEAFH 655
Q+R+ E + L ++ ++RE+ + Q+E+ RE E ++++E+++R E++L+
Sbjct: 721 EQERRREQER----LQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQ 776
Query: 656 ERKEK 660
E+K K
Sbjct: 777 EKKAK 781
Score = 43.5 bits (101), Expect = 0.001
Identities = 55/266 (20%), Positives = 107/266 (40%), Gaps = 13/266 (4%)
Query: 481 EKAKNEPAGKKLSDRKECEVKKEKLSSVDRHHSVEIKIEKTVIKKEEKIEKKEEKKPEDI 540
+K EPA S R C E+L +V+ V + +K ++ E + E + PE+
Sbjct: 341 KKTAEEPAA---SGRIICHSYLERLLNVEVPQKVGSE-QKEPPEEAEPVAAAEPEVPENN 396
Query: 541 KKEEKDQDELK-------PGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVKTTSRSKE 593
++ + P P S T S + +T D + P + + S +
Sbjct: 397 GNNSWPHNDTEIANSTPNPKPAASSPETPSAGQQEAKTDQADGPREPPQSARRKRSYKQA 456
Query: 594 RSSKSQDRKSESKEKRDILSFDKIKEQRERERQRQREREIRETERRREREQREREQR--L 651
S +++ E +E + S + R + +R + R +
Sbjct: 457 VSELDEEQHLEDEELQPPRSKTPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVM 516
Query: 652 EAFHERKEKARLQRERLQLECQRQRLERERMERERLERERMRVERERRKEQERIHREREE 711
++F +R R+ + +E +RQRLE R + E + R +VE ++R+ E + +REE
Sbjct: 517 KSFIKRNTPLRMDPKCSFVEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREE 576
Query: 712 LRRQQEQLRYEQERRPGRRPYDLDRR 737
R+ Q R E+ + ++++
Sbjct: 577 RLRKVLQARERVEQMKEEKKKQIEQK 602
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 89.7 bits (221), Expect = 1e-17
Identities = 66/219 (30%), Positives = 116/219 (52%), Gaps = 20/219 (9%)
Query: 523 IKKEEKIEKKEEKKPEDIKKEEKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPV 582
++++E+ E+ +K E+ K+ ++ +LK R + + ER M + K + +
Sbjct: 541 LRRKEEAEQLRRQKVEEDKRRRLEEVKLK-----REERLRKVLQARERVEQMKEEKKKQI 595
Query: 583 ------ISVKTTSRSKERSSKSQ-DRKSESKEKRDILSFDKIKEQRERERQRQREREIRE 635
I KT +ER ++ + +K+ +K+ ++ + K +E+ R R Q+E E R
Sbjct: 596 EQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERR 655
Query: 636 TERRREREQREREQRLEAFHERKEKA--RLQRERLQLECQRQRLERERMERERLERERMR 693
+ ++++ E ++RL E K A R Q R Q +++R E+ER E+ER E+ER
Sbjct: 656 HQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQL 715
Query: 694 VERERRKEQERIHRERE------ELRRQQEQLRYEQERR 726
E+ERR+EQER+ ERE LR Q+EQL+ E E +
Sbjct: 716 AEQERRREQERLQAERELQEREKALRLQKEQLQRELEEK 754
Score = 88.6 bits (218), Expect = 3e-17
Identities = 72/249 (28%), Positives = 132/249 (53%), Gaps = 23/249 (9%)
Query: 482 KAKNEPAGKKLSDRKECE-VKKEKLSSVDRHHSVEIKIEKT-----VIKKEEKIEKKEEK 535
K K + L ++E E ++++K+ R E+K+++ V++ E++E+ +E+
Sbjct: 531 KEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEE 590
Query: 536 KPEDIKK-----EEKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVKTTSR 590
K + I++ +EK + + K+ ++ ME K + E
Sbjct: 591 KKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQE 650
Query: 591 SKERSSKS--QDRKSESKEK-RDILSFDKIKEQRERER--QRQREREIRETERRREREQR 645
+ER + Q +K E +E+ R ++ EQRE+ER Q +RE+E RE E RRE+E+R
Sbjct: 651 EEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQE-RREQERR 709
Query: 646 EREQRLEAFHERKEKARLQRER-LQ-----LECQRQRLERERMERERLERERMRVERERR 699
E+E++L R+E+ RLQ ER LQ L Q+++L+RE E+++ E ++ ER+ +
Sbjct: 710 EQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQ 769
Query: 700 KEQERIHRE 708
+EQE+ +E
Sbjct: 770 EEQEKKAKE 778
Score = 57.8 bits (138), Expect = 5e-08
Identities = 65/323 (20%), Positives = 142/323 (43%), Gaps = 44/323 (13%)
Query: 488 AGKKLSDRKECEVKKEKLSSVDRHHSVEIKIEKTVIKKEEKIEKKEEKKPEDIKKEEKDQ 547
AG++ + + + +E S R S + + + + +E+ +E +E + P +
Sbjct: 427 AGQQEAKTDQADGPREPPQSARRKRSYKQAVSE--LDEEQHLEDEELQPP---------R 475
Query: 548 DELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVKTTSRS--KERSSKSQDRKSES 605
+ P S+V + R TV ++ P + ++ +S K + D K +
Sbjct: 476 SKTPSSPCPASKVVRP-LRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKE 534
Query: 606 KEKRDIL----SFDKIKEQRERERQRQREREIRETERRREREQREREQRLEAFHERKEKA 661
+++ + L ++++ Q+ E +R+R E++ R R+ + +R+E E K+K
Sbjct: 535 RQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKK- 593
Query: 662 RLQRERLQLECQRQRLERERMERERLERE----RMRVERERRKEQERIHRER-----EEL 712
+++++ Q++ + ++ + ER+ E+ +++ +M RRK++E R R EE
Sbjct: 594 QIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEE 653
Query: 713 RRQQEQLRYEQERRPGRRPYDLDRRDDAYWPEGKRVAMEDRYRADFPRPDHRFHDFDHRD 772
RR QE L+ ++E E R A E + A+ + R + ++
Sbjct: 654 RRHQELLQKKKEEE----------------QERLRKAAEAKRLAEQREQERREQERREQE 697
Query: 773 RGQYQDHAIDRREGSRPMMGDHR 795
R + + +RRE R + R
Sbjct: 698 RREQERREQERREQERQLAEQER 720
Score = 49.7 bits (117), Expect = 1e-05
Identities = 43/185 (23%), Positives = 94/185 (50%), Gaps = 23/185 (12%)
Query: 478 ISVEKAKNEPAGKKLSDRKECEVKKEKLSSVDRHHSVEIKIEKTVIKKEEKIEKKEEKKP 537
++ EKAK + A KK+ +E E ++++ R ++ + E+ + +E ++KK+E++
Sbjct: 614 LAEEKAKKKAAAKKM---EEVEARRKQEEEARRLRWLQQEEEER--RHQELLQKKKEEEQ 668
Query: 538 EDIKKEEKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVKTTSRSKERSSK 597
E ++K E K R + + R + ++ + E R +ER
Sbjct: 669 ERLRKAA----EAKRLAEQREQERREQERREQERREQERREQE--------RREQERQLA 716
Query: 598 SQDRKSESKEKRDILSFDKIKEQRERERQRQREREIRETERRREREQRER--EQRLEAFH 655
Q+R+ E + L ++ ++RE+ + Q+E+ RE E ++++E+++R E++L+
Sbjct: 717 EQERRREQER----LQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQ 772
Query: 656 ERKEK 660
E+K K
Sbjct: 773 EKKAK 777
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 89.4 bits (220), Expect = 1e-17
Identities = 69/276 (25%), Positives = 145/276 (52%), Gaps = 29/276 (10%)
Query: 490 KKLSDRKECEVKKEKLSSVDRHHSVEIKI---EKTVIKKEEKIEKKEEK---KPEDIKKE 543
+K+ +++E ++EK+ ++ E K+ E+ + ++EEKI ++EEK + E I ++
Sbjct: 451 EKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQ 510
Query: 544 EKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVKTTSRSKERSSKSQDRKS 603
EK ++E K + + + + E+ E + K +E + Q+ K
Sbjct: 511 EKIREEEKR--QEQEEMWRQEEKIREQ---------EEIWRQKEKIHEQEEKIRKQEEKM 559
Query: 604 ESKEKRDILSFDKIKEQRERERQRQREREIRETERRREREQREREQRLEAFHERKEKARL 663
+E++ +KI+EQ E+ RQ E+ + E+ RE+E++ REQ E E++EK
Sbjct: 560 WRQEEKMHDQEEKIREQEEKV-WRQEEKIREQEEKIREQEEKIREQE-EMTQEQEEKMGE 617
Query: 664 QRERLQLECQRQRLERERMERERLERERMRVERERRKEQERIHREREELRRQQEQLRYEQ 723
Q E++ C+++ +E+ E+ R + E++R + ++ +EQE RE+EE+ ++QE+ +EQ
Sbjct: 618 QEEKM---CEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQ 674
Query: 724 ERRPGRRPYDLD-------RRDDAYWPEGKRVAMED 752
E + + + R+++ W + R+ ++
Sbjct: 675 EEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQE 710
Score = 86.3 bits (212), Expect = 1e-16
Identities = 64/245 (26%), Positives = 128/245 (52%), Gaps = 24/245 (9%)
Query: 519 EKTVIKKEEKIEKKEEKKPEDIKKEEKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSK 578
E+ + ++EEKI++ EEK E +K + +++++ M R M K
Sbjct: 360 EEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIR-----------EQEEKMRRQEEMMWEK 408
Query: 579 GEPVISVKTTSRSKERSSKSQDRKSESKEKRDILSFDKIKEQ---RERERQRQREREIRE 635
E + + KE + Q+ KE++ +K+ EQ RE+E +RQ E +IRE
Sbjct: 409 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIRE 468
Query: 636 TERRREREQREREQRLEAFHERKEKARLQRERLQL------ECQRQRLERERMERERLER 689
E+R+E+E + Q E E++EK R Q E++ E ++ R E +R E+E + R
Sbjct: 469 QEKRQEQEAKMWRQE-EKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWR 527
Query: 690 --ERMRVERERRKEQERIHREREELRRQQEQLRYEQERRPGRRPYDLDRRDDAYWPEGKR 747
E++R + E +++E+IH + E++R+Q+E++ + QE + + + +++ W + ++
Sbjct: 528 QEEKIREQEEIWRQKEKIHEQEEKIRKQEEKM-WRQEEKMHDQEEKIREQEEKVWRQEEK 586
Query: 748 VAMED 752
+ ++
Sbjct: 587 IREQE 591
Score = 84.3 bits (207), Expect = 5e-16
Identities = 64/267 (23%), Positives = 143/267 (53%), Gaps = 11/267 (4%)
Query: 495 RKECEVKKEKLSSVDRHHSVEIKIEKTVIKKEEKIEKKEEK--KPEDI--KKEEKDQDEL 550
R++ E +E+ + R + + E+ + ++EE + +KEEK + E++ +KEEK + EL
Sbjct: 385 REQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIR-EL 443
Query: 551 KPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVKTTSRSKERSSKSQDRKSESKEKRD 610
+ + ++ + + E + ++ K + + K R + + R+ E K R
Sbjct: 444 EEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQ 503
Query: 611 ILSFDKIKEQRERERQRQREREIRETERRREREQREREQRLEAFHERKEKARLQRERL-- 668
+ ++ RE E+++++E R+ E+ RE+E+ R++ E HE++EK R Q E++
Sbjct: 504 EEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQK--EKIHEQEEKIRKQEEKMWR 561
Query: 669 QLECQRQRLERERMERERL--ERERMRVERERRKEQERIHREREELRRQQEQLRYEQERR 726
Q E + E+ R + E++ + E++R + E+ +EQE RE+EE+ ++QE+ EQE +
Sbjct: 562 QEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEK 621
Query: 727 PGRRPYDLDRRDDAYWPEGKRVAMEDR 753
+ + +++ + +++ +++
Sbjct: 622 MCEQEEKMQEQEEKMRRQEEKIREQEK 648
Score = 75.1 bits (183), Expect = 3e-13
Identities = 76/314 (24%), Positives = 159/314 (50%), Gaps = 23/314 (7%)
Query: 460 EATKCISHLHRT-ELHGRMISVEKAKNEPAG-KKLSDRKECEVKKEKLS---SVDRHHSV 514
EA IS LH + + G + E+A + A KK +DR E+ KE+ + + R+
Sbjct: 220 EARDLISRLHDSWKFAGEL---EQALSAVATQKKKADRYIEELTKERDALSLELYRNTIT 276
Query: 515 EIKIEKTVIKKEEKIEKKEEKKPE------DIKKEEKDQDELKPGPTNRSRVTKSGSRGM 568
+ ++++ K +EK++ E +K E ++K++ + L P ++ G
Sbjct: 277 DEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQ 336
Query: 569 ERTVVMDKSKGEPVISVKTTSRSKERSSKSQDRKSESKEKRDILSFDKIKEQRERERQRQ 628
+ + E + + + +E+ + +++ E +EK +KI+EQ E+ R+ Q
Sbjct: 337 SVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQE-EKIREQEEKIRE-Q 394
Query: 629 REREIRETERRREREQREREQRLEAFHERKEKARLQRERLQLECQRQRLERERMERERLE 688
E+ R+ E E+E++ R Q E E++EK R Q E + + ++ R E+M E
Sbjct: 395 EEKMRRQEEMMWEKEEKMRRQE-EMMWEKEEKMRRQEEMMWEKEEKIRELEEKMH----E 449
Query: 689 RERMRVERERRKEQERIHREREELRRQQEQLRYEQERRPGRRPYDLDRRDDAYWPEGKRV 748
+E++R + E+R+E+E+I RE+E+ R++QE + QE + + + +++ W + +++
Sbjct: 450 QEKIREQEEKRQEEEKI-REQEK-RQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKI 507
Query: 749 AMEDRYRADFPRPD 762
+++ R + R +
Sbjct: 508 HEQEKIREEEKRQE 521
Score = 72.0 bits (175), Expect = 2e-12
Identities = 62/232 (26%), Positives = 121/232 (52%), Gaps = 25/232 (10%)
Query: 481 EKAKNEPAGKKLSDRKECEVKKEKLSSVDRHHSVEIKIEKTVIKKEEKIEKKEEKKPEDI 540
EK + E +K +++E ++EK+ + + KI + +EEKI K+EEK
Sbjct: 511 EKIREE---EKRQEQEEMWRQEEKIREQEEIWRQKEKIHE----QEEKIRKQEEKM---W 560
Query: 541 KKEEKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVKTTSRSKERSSKSQD 600
++EEK D+ + +V + + E+ E + + R +E ++ Q+
Sbjct: 561 RQEEKMHDQEEKIREQEEKVWRQEEKIREQE--------EKIREQEEKIREQEEMTQEQE 612
Query: 601 RKSESKEKRDILSFDKIKEQRERERQRQREREIRETERR-REREQREREQRLEAFHERKE 659
K +E++ +K++EQ E+ R++E +IRE E++ RE+E++ REQ E E++E
Sbjct: 613 EKMGEQEEKMCEQEEKMQEQEEK--MRRQEEKIREQEKKIREQEEKIREQE-EMMQEQEE 669
Query: 660 KARLQRERLQLECQRQRLERERMERERLERERMRVERERRKEQERIHREREE 711
K Q E++ C+++ +E+ E+ R + E+M + R ++QE +E +E
Sbjct: 670 KMWEQEEKM---CEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQE 718
Score = 58.9 bits (141), Expect = 2e-08
Identities = 57/226 (25%), Positives = 110/226 (48%), Gaps = 38/226 (16%)
Query: 490 KKLSDRKECEVKKEKLSSVDRHHSVEIKI---EKTVIKKEEKIEKKEEKKPEDIKKEEKD 546
+K+ +++E +KEK+ H E KI E+ + ++EEK+ +EEK E +K +
Sbjct: 530 EKIREQEEIWRQKEKI------HEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQ 583
Query: 547 QDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVKTTSRSKERSSKSQDRKSESK 606
+++++ + E T ++ GE +E Q+ K + +
Sbjct: 584 EEKIREQEEKIREQEEKIREQEEMTQEQEEKMGE-----------QEEKMCEQEEKMQEQ 632
Query: 607 EKRDILSFDKIKEQRERERQRQREREIRETERR-REREQREREQRLEAFHERKEKARLQR 665
E++ +KI+EQ E++IRE E + RE+E+ +EQ E E++EK Q
Sbjct: 633 EEKMRRQEEKIREQ---------EKKIREQEEKIREQEEMMQEQE-EKMWEQEEKMCEQE 682
Query: 666 ERLQLECQRQRLERERMERERLERERMRVERERRKEQERIHREREE 711
E++Q ++ E+ R + E++ + +R+ ++ K QE H+E E
Sbjct: 683 EKMQ-----EQEEKMRRQEEKMWEQEVRLRQQEEKMQE--HQEHLE 721
Score = 43.9 bits (102), Expect = 7e-04
Identities = 43/173 (24%), Positives = 85/173 (49%), Gaps = 23/173 (13%)
Query: 490 KKLSDRKECEVKKEKLSSVDRHHSVEIKIEKTVIKKEEKIEKKEEKKPEDIKK----EEK 545
+K+ D++E +E+ V R + E+ + ++EEKI ++EE E +K EEK
Sbjct: 564 EKMHDQEE--KIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEK 621
Query: 546 --DQDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVKTTSRSKERSSKSQDRKS 603
+Q+E + R + R E+ + + K R +E + Q+ K
Sbjct: 622 MCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEK----------IREQEEMMQEQEEKM 671
Query: 604 ESKEKRDILSFDKIKEQRERERQRQR---EREIRETERRREREQREREQRLEA 653
+E++ +K++EQ E+ R+++ E+E+R R++E + +E ++ LEA
Sbjct: 672 WEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVR--LRQQEEKMQEHQEHLEA 722
>gi|22035606 mitogen-activated protein kinase kinase kinase kinase 4
isoform 3 [Homo sapiens]
Length = 1212
Score = 89.0 bits (219), Expect = 2e-17
Identities = 71/264 (26%), Positives = 124/264 (46%), Gaps = 14/264 (5%)
Query: 542 KEEKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISV---KTTSRSKERSSKS 598
K+ D+ K G + + SGS E V + + +++V T R R +
Sbjct: 303 KDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQE 362
Query: 599 QDRKSESKEKRDILSFDKIKEQRERERQ----RQREREIRETERRREREQREREQRLEAF 654
+SE+ ++ +L +++EQ E +RQ RQ+ E ++ +RRR EQ+ RE+
Sbjct: 363 NKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQ 422
Query: 655 HERKEKARLQRERLQLECQRQRLERERMERERLERERMRVERERRKEQERIHREREELRR 714
ER+++ R Q E+ +LE + +R +E ER R E E+ RVER EQE I R+ EE +R
Sbjct: 423 QEREQRRREQEEKRRLE-ELERRRKEEEERRRAEEEKRRVER----EQEYIRRQLEEEQR 477
Query: 715 QQEQLRYEQERRPGRRPYDLDRRDDAYWPEGKRVAMEDRYRADFPRPDHRFHDFDHRDRG 774
E L+ + + +D RR + ++R + F P+ + H ++ DR
Sbjct: 478 HLEVLQQQLLQEQAMLLHD-HRRPHPQHSQQPPPPQQERSKPSFHAPEPKAH-YEPADRA 535
Query: 775 QYQDHAIDRREGSRPMMGDHRDGQ 798
+ + + S P + G+
Sbjct: 536 REVEDRFRKTNHSSPEAQSKQTGR 559
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 88.6 bits (218), Expect = 3e-17
Identities = 69/273 (25%), Positives = 138/273 (50%), Gaps = 18/273 (6%)
Query: 490 KKLSDRKECEVKKEKLSSVDRHHSVEIKIEKTVIKKEEKIEKKEEKKPEDIKKEEKDQDE 549
+K+ +++E ++EK+ ++ E K+ + +EEKI ++EEK E KK + +++
Sbjct: 390 EKIREQEEKRQEEEKIREQEKRQEQEAKMWR----QEEKIREQEEKIREQEKKMWRQEEK 445
Query: 550 LKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVKTTSRSKERSSKSQDRKSESKEKR 609
+ R + M R + + E + K +E+ K +++ +EK
Sbjct: 446 IHEQEKIREEEKRQEQEEMWRQEEKIREQ-EEIWRQKEKMHEQEKIRKQEEKVWRQEEKM 504
Query: 610 DILSFDKIKEQRERERQRQREREIRETERRREREQREREQRLEAFHERKEKARLQRERLQ 669
+KI+EQ E+ RQ E+ + E+ RE+E++ REQ E E++EK Q E++Q
Sbjct: 505 HDQE-EKIREQEEK-MWRQEEKIREQEEKIREQEEKIREQE-EMMQEQEEKMGEQEEKMQ 561
Query: 670 LECQRQRLE----------RERMERERLERERMRVERERRKEQERIHREREELRRQQEQL 719
+ + +R E RE+ E+ R + E++ + E+ +EQE + +E+EE +QE+
Sbjct: 562 EQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEK 621
Query: 720 RYEQERRPGRRPYDLDRRDDAYWPEGKRVAMED 752
EQE + + + R+++ W + R+ ++
Sbjct: 622 MCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQE 654
Score = 86.3 bits (212), Expect = 1e-16
Identities = 55/260 (21%), Positives = 145/260 (55%), Gaps = 16/260 (6%)
Query: 501 KKEKLSSVDR--HHSVEIKIEKTVIKKEEKIEKKEEKKPEDIK---KEEKDQDELKPGPT 555
K+EK+ ++ H +I+ ++ ++EEKI ++E+++ ++ K +EEK +++ +
Sbjct: 375 KEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIRE 434
Query: 556 NRSRVTKSGSRGMERTVVMDKSKGEPVISVKTTSRSKERSSKSQD--RKSESKEKRDILS 613
++ + + E+ + ++ K + + R +E+ + ++ R+ E +++ +
Sbjct: 435 QEKKMWRQEEKIHEQEKIREEEKRQ---EQEEMWRQEEKIREQEEIWRQKEKMHEQEKIR 491
Query: 614 FDKIKEQRERERQRQREREIRETERRREREQREREQRLEAFHERKEKARLQRERLQLECQ 673
+ K R+ E+ +E +IRE E + R++ + ++ E E++EK R Q E +Q + +
Sbjct: 492 KQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEE 551
Query: 674 RQRLERERMERERLERERMRVERER-RKEQERIHREREELRRQQEQLRYEQERRPGRRPY 732
+ + E+M+ E+E+MR + E+ R+++E+I ++E++R Q+E++ +EQE + +
Sbjct: 552 KMGEQEEKMQ----EQEKMRRQEEKIREQEEKIREQKEKIREQEEKI-WEQEEKIREQEE 606
Query: 733 DLDRRDDAYWPEGKRVAMED 752
+ +++ W + +++ ++
Sbjct: 607 MMQEQEEKMWEQEEKMCEQE 626
Score = 82.4 bits (202), Expect = 2e-15
Identities = 70/268 (26%), Positives = 141/268 (52%), Gaps = 17/268 (6%)
Query: 495 RKECEVKKEKLSSVDRHHSVEIKIEKTVIKKEEKIEKKEEK--KPEDI--KKEEKDQDEL 550
R++ E +E+ + R + + E+ + ++EE + +KEEK + E++ +KEEK + EL
Sbjct: 324 REQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIR-EL 382
Query: 551 KPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVKTTSRSKERSSKSQDRKSESKEKRD 610
+ + ++ + + E + ++ K + + +E + Q+ K +EK+
Sbjct: 383 EEKMHEQEKIREQEEKRQEEEKIREQEKRQ---EQEAKMWRQEEKIREQEEKIREQEKKM 439
Query: 611 ILSFDKIKEQ---RERERQRQREREIRETERRREREQREREQRLEAFHERKEKARLQRER 667
+KI EQ RE E+++++E R+ E+ RE+E+ R++ E HE+ EK R Q E+
Sbjct: 440 WRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQK--EKMHEQ-EKIRKQEEK 496
Query: 668 LQLECQRQRLERERMERERLERERMRVERERRKEQERIHREREELRRQQEQLRYEQERRP 727
+ + ++ + E++ R + E+M + E+ +EQE RE+EE R+QE++ EQE +
Sbjct: 497 VWRQEEKMHDQEEKI---REQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKM 553
Query: 728 GRRPYDLDRRDDAYWPEGKRVAMEDRYR 755
G + + ++ E K E++ R
Sbjct: 554 GEQEEKMQEQEKMRRQEEKIREQEEKIR 581
Score = 80.5 bits (197), Expect = 7e-15
Identities = 68/270 (25%), Positives = 138/270 (51%), Gaps = 30/270 (11%)
Query: 481 EKAKNEPAGKKLSDRKECEVKKEKLSSVDRHHSVEIKI-EKTVIKKEEKIEKKEEKKPED 539
EK + E ++ R+E E K + R +I+ EK + ++EEKI ++E+ + E+
Sbjct: 397 EKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEE 456
Query: 540 IKKEEKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVKTTSRSKERSSKSQ 599
++E+++ + + + + + E+ + + + E V + +E + Q
Sbjct: 457 KRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKI--RKQEEKVWRQEEKMHDQEEKIREQ 514
Query: 600 DRKSESKEKRDILSFDKIKEQRERERQRQ------------REREIRETERRREREQRER 647
+ K +E++ +KI+EQ E+ R+++ +E +++E E+ R +E++ R
Sbjct: 515 EEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIR 574
Query: 648 EQRLEAFHERKEKARLQRERLQLECQRQRLERERMERERLER-----ERMRVERERRKEQ 702
EQ E E+KEK R Q E++ + ++ R E+E M +E+ E+ E+M + E+ +EQ
Sbjct: 575 EQE-EKIREQKEKIREQEEKIWEQEEKIR-EQEEMMQEQEEKMWEQEEKMCEQEEKMQEQ 632
Query: 703 ERIHREREE--------LRRQQEQLRYEQE 724
E R +EE LR+Q+E+++ QE
Sbjct: 633 EEKMRRQEEKMWEQEVRLRQQEEKMQEHQE 662
Score = 77.8 bits (190), Expect = 4e-14
Identities = 53/214 (24%), Positives = 111/214 (51%), Gaps = 16/214 (7%)
Query: 519 EKTVIKKEEKIEKKEEK---KPEDIKKEEKDQDELKPGPTNRSRVTKSGSRGMERTVVMD 575
E+ + ++EEKI ++EEK + E ++++E+ E + + + M R M
Sbjct: 313 EEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMM 372
Query: 576 KSKGEPVISVKTTSRSKERSSKSQDRKSESKEKRDILSFDKIKEQRERERQR----QRER 631
K E + R E Q++ E +EKR +KI+EQ +R+ Q ++E
Sbjct: 373 WEKEEKI-------RELEEKMHEQEKIREQEEKRQ--EEEKIREQEKRQEQEAKMWRQEE 423
Query: 632 EIRETERRREREQREREQRLEAFHERKEKARLQRERLQLECQRQRLERERMERERLERER 691
+IRE E + ++++ ++ E HE+++ ++ + Q E RQ + E ++E+
Sbjct: 424 KIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEK 483
Query: 692 MRVERERRKEQERIHREREELRRQQEQLRYEQER 725
M + + RK++E++ R+ E++ Q+E++R ++E+
Sbjct: 484 MHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEK 517
Score = 75.1 bits (183), Expect = 3e-13
Identities = 60/233 (25%), Positives = 116/233 (49%), Gaps = 30/233 (12%)
Query: 519 EKTVIKKEEKIEKKEEK---KPEDIKKEEKDQDELKPGPTNRSRVTKSGSRGMERTVVMD 575
E+ + ++EEKI++ EEK + E I+++E+ E + + + M R M
Sbjct: 299 EEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMM 358
Query: 576 KSKGEPVISVKTTSRSKERSSKSQDRKSESKEKRDILSFDKIKEQRERERQRQREREIRE 635
K E + ++ KE + + K +EK RE+E +RQ E +IRE
Sbjct: 359 WEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKI-----------REQEEKRQEEEKIRE 407
Query: 636 TERRREREQREREQRLEAFHERKEKARLQRERLQLECQRQRLERERMERERLERERMRVE 695
E+R+E+E + Q E E++EK R Q +++ R E + E+E++R E
Sbjct: 408 QEKRQEQEAKMWRQE-EKIREQEEKIREQEKKMW-----------RQEEKIHEQEKIR-E 454
Query: 696 RERRKEQERIHREREELRRQQEQLRYEQERRPGRRPYDLDRRDDAYWPEGKRV 748
E+R+EQE + R+ E++R Q+E R +++ + + ++++ W + +++
Sbjct: 455 EEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEK---IRKQEEKVWRQEEKM 504
Score = 73.2 bits (178), Expect = 1e-12
Identities = 63/258 (24%), Positives = 133/258 (51%), Gaps = 12/258 (4%)
Query: 470 RTELHGRMISVEKAKNEPAGKKLSDRKECEVKKEKLSSVDRHHSVEIKIEKTVI-KKEEK 528
R E +M E+ E K K+ ++EK+ ++ E + E+ + ++EEK
Sbjct: 411 RQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEK 470
Query: 529 IEKKEE--KKPEDIKKEEKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVK 586
I ++EE ++ E + ++EK + + + ++ + E+ M + + E + +
Sbjct: 471 IREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQE-EKIREQE 529
Query: 587 TTSRSKERSSKSQDRKSESKEKRDILSFDKIKEQRERERQRQREREIRETERRREREQRE 646
R +E + Q+ + +E++ +K++EQ + RQ ++ RE + E+ RE++++
Sbjct: 530 EKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIRE--QEEKIREQKEKI 587
Query: 647 REQRLEAFHERKEKARLQRERLQLECQRQRLERERM----ERERLERERMRVERERRKEQ 702
REQ E E++EK R Q E +Q + ++ + E+M E+ + + E+MR + E+ EQ
Sbjct: 588 REQE-EKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQ 646
Query: 703 E-RIHREREELRRQQEQL 719
E R+ ++ E+++ QE L
Sbjct: 647 EVRLRQQEEKMQEHQEHL 664
Score = 72.4 bits (176), Expect = 2e-12
Identities = 79/323 (24%), Positives = 161/323 (49%), Gaps = 38/323 (11%)
Query: 460 EATKCISHLHRT-ELHGRMISVEKAKNEPAG-KKLSDRKECEVKKEKLSSVDRHHSVEIK 517
EA IS LH + + G + E+A + A KK +DR E+ KE+ ++ ++
Sbjct: 159 EARDLISRLHDSWKFAGEL---EQALSAVATQKKKADRYIEELTKER-------DALSLE 208
Query: 518 IEKTVIKKEEKIEKKEEKKPEDIKKEEKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKS 577
+ + I EE +++K K E ++ E ++ E++ R + + + + ++
Sbjct: 209 LYRNTITDEE-LKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEA 267
Query: 578 ----KGEPVISVKTTSRSKE-----RSSKSQDRKSESKEKRDILSFDKIKEQRERER-QR 627
K +S K ++ +E R ++ Q+ K +E++ +KI+EQ E+ R Q
Sbjct: 268 DHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQE 327
Query: 628 QREREIRETERRREREQREREQRL----EAFHERKEKARLQRERLQLECQRQRLERERM- 682
++ RE E RR+E E+E+++ E E++EK R E + + ++ R E+M
Sbjct: 328 EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMH 387
Query: 683 --------ERERLERERMRVERERRKEQERIHREREELRRQQEQLRYEQERRPGRRPYDL 734
E +R E E++R + +R++++ ++ R+ E++R Q+E++R EQE++ R+ +
Sbjct: 388 EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR-EQEKKMWRQEEKI 446
Query: 735 DRRDDAYWPEGKRVAMEDRYRAD 757
++ E KR E+ +R +
Sbjct: 447 HEQEKIR-EEEKRQEQEEMWRQE 468
Score = 63.2 bits (152), Expect = 1e-09
Identities = 53/222 (23%), Positives = 118/222 (53%), Gaps = 25/222 (11%)
Query: 490 KKLSDRKECEVKKEKLSSVDRHHSVEIKIEKTVIKKEEKIEKKEEKKPEDIKKEEKDQDE 549
+K+ +++E +KEK+ ++ K E+ V ++EEK+ +EEK E +K + +++
Sbjct: 469 EKIREQEEIWRQKEKMHEQEKIR----KQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEK 524
Query: 550 LKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVKTTSRSKERSSKSQDRKSESKEKR 609
++ ++ + + E+ +M + + E + + + +E+ + +++ E +EK
Sbjct: 525 IRE---QEEKIREQEEKIREQEEMMQEQE-EKMGEQEEKMQEQEKMRRQEEKIREQEEK- 579
Query: 610 DILSFDKIKEQRERERQRQREREIRETERRREREQREREQRLEAFHERKEKARLQRERLQ 669
I+EQ+E+ R+ Q E+ + E+ RE+E+ +EQ E E++EK Q E++Q
Sbjct: 580 -------IREQKEKIRE-QEEKIWEQEEKIREQEEMMQEQE-EKMWEQEEKMCEQEEKMQ 630
Query: 670 LECQRQRLERERMERERLERERMRVERERRKEQERIHREREE 711
++ E+ R + E++ + +R+ ++ K QE H+E E
Sbjct: 631 -----EQEEKMRRQEEKMWEQEVRLRQQEEKMQE--HQEHLE 665
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 88.6 bits (218), Expect = 3e-17
Identities = 70/276 (25%), Positives = 128/276 (46%), Gaps = 33/276 (11%)
Query: 487 PAGKKLSDRKECEVKKEKLSSVDRHHSVEIKIEKTVIKKEEKIEKK--EEKKPEDIKKEE 544
P+ + +D E E +++ S R EI+ +TV K +K + + EE K ED +KEE
Sbjct: 133 PSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEE 192
Query: 545 KDQDELKPGPTNRSRVT----KSGSRGMERTVVMDKSKGEPVISVKTTSRSKERSSKSQD 600
+++++ K G ++V + + E TVVM G+ SS+
Sbjct: 193 EEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQI-------------SSEEPK 239
Query: 601 RKSESKEKRDILSFDKIKEQRERERQRQREREIRETERRREREQREREQRLEAFHERKEK 660
++ E ++ D +S + E+ ++ER E R R + E +R++A ++K
Sbjct: 240 QEEEREQGSDEISHHEKMEEEDKER----------AEAERARLEAEERERIKAEQDKK-- 287
Query: 661 ARLQRERLQLECQRQRLERERMERERLERERMRVERERRKEQERIHREREELRRQQEQLR 720
+ ER ++E + + +ER RE ERERMR E +R E+ + +E E+ ++ Q
Sbjct: 288 --IADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRI 345
Query: 721 YEQERRPGRRPYDLDRRDDAYWPEGKRVAMEDRYRA 756
E+E+R + + E +R E+ +A
Sbjct: 346 KEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKA 381
Score = 68.2 bits (165), Expect = 4e-11
Identities = 68/290 (23%), Positives = 131/290 (45%), Gaps = 42/290 (14%)
Query: 481 EKAKNEPAGKKLSDRKECEVKKEKLSS------VDRHHSVEIKIEKTVIKKE-----EKI 529
E+ +N+ +K +E ++K EK+ V+ + E K++ V+KK+ K+
Sbjct: 385 EQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKV 444
Query: 530 EKKEEKKPED---IKKEEKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVK 586
+ K EK ED KKEE +++K + V MD+ KG + +
Sbjct: 445 QAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKS----------FMDRKKGFTEVKSQ 494
Query: 587 TTSRSKERSSKSQDRKSESKEKRDILSFDKIKEQRERERQRQREREIRETERRREREQRE 646
+ +++ S + + + +E E Q E R E RR R + E
Sbjct: 495 NGEFMTHKLKHTENTFSRPGGRASV-------DTKEAEGAPQVEAGKRLEELRRRRGETE 547
Query: 647 REQRLEAFHERKEKARLQRERLQLECQRQR--LERERMERERLERER-MRVERERRKEQE 703
E+ E +++++A L+ E L+ + + +R LE E R++ E +R +R E E+R+ +E
Sbjct: 548 SEE-FEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKE 606
Query: 704 RIHREREELRRQQEQLRYEQERRPGRRPYDLDRRDDAYWPEGKRVAMEDR 753
I R R E +++++ E ++P+ + P+G + +E+R
Sbjct: 607 EIERRRAEAAEKRQKMP-EDGLSDDKKPFK------CFTPKGSSLKIEER 649
Score = 60.1 bits (144), Expect = 1e-08
Identities = 50/229 (21%), Positives = 108/229 (47%), Gaps = 21/229 (9%)
Query: 478 ISVEKAKNEPAGKKLSDRKECEVKKEK--LSSVDRHHSVEIKIEKTVIKKEEKIEKKEEK 535
I EK + + GK ++++K E K + L +++ ++ +++++ KKEE
Sbjct: 404 IKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEI 463
Query: 536 KPEDIKKEEKDQDELKPGPTNRSRVTKSGSRGME-----------------RTVVMDKSK 578
K E IKK+++ ++E+K + T+ S+ E +D +
Sbjct: 464 KDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKE 523
Query: 579 GEPVISVKTTSRSKERSSKSQDRKSESKEKRDILSFDKIKEQRERERQRQREREI-RETE 637
E V+ R +E + + +SE EK + E E +++R+ R++ E E
Sbjct: 524 AEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEE 583
Query: 638 RRREREQREREQRLEAFHERKEKARLQRERLQLECQRQRLERERMERER 686
+RR++E+ +R+ R E +R+ K ++R R + +RQ++ + + ++
Sbjct: 584 QRRKQEEADRKLR-EEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDK 631
Score = 43.5 bits (101), Expect = 0.001
Identities = 48/206 (23%), Positives = 87/206 (42%), Gaps = 17/206 (8%)
Query: 607 EKRDILSFDKIKEQR-ERERQRQREREIRETERRREREQREREQRLEAFHERKEKARLQR 665
E+R L K +E R E ER + + E E RER +R R++RL +++E+ L +
Sbjct: 5 ERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERL---RQKQEEESLGQ 61
Query: 666 ERLQLECQRQRLERERMERERL-------ERERMRVERERRKEQERIHREREELRRQQE- 717
Q+E Q + + + E +ER R+E+ R R +E L RQ+E
Sbjct: 62 VTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEF 121
Query: 718 --QLRYEQERRPGRRPYDLDRRDDAYWPEGKRVAMEDRY---RADFPRPDHRFHDFDHRD 772
+ P RR + ++ E K + ++RY + ++ +D+ +
Sbjct: 122 DPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAE 181
Query: 773 RGQYQDHAIDRREGSRPMMGDHRDGQ 798
+ +D + E +P G + Q
Sbjct: 182 ENKKEDKEKEEEEEEKPKRGSIGENQ 207
Score = 39.3 bits (90), Expect = 0.018
Identities = 21/61 (34%), Positives = 34/61 (55%), Gaps = 5/61 (8%)
Query: 651 LEAFHERKEKARLQRERLQLECQRQRLERERMERERLERERMRVERERRKEQERIHRERE 710
++ F R+E R +RE ++LE +R +R + E R ER RR QER+ +++E
Sbjct: 1 MDDFERRRELRRQKREEMRLEAERIAYQRNDDDEEEAAR-----ERRRRARQERLRQKQE 55
Query: 711 E 711
E
Sbjct: 56 E 56
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 88.2 bits (217), Expect = 3e-17
Identities = 71/275 (25%), Positives = 147/275 (53%), Gaps = 18/275 (6%)
Query: 461 ATKCISHLHRTELHGRMISVEKAKNEPAGKKLSDRKE-CEVKKEKLSSVDRHHSVEIKIE 519
+ K + + EL R+ ++ K +K+ +R+E + ++EK+ + + E
Sbjct: 266 SAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQ---E 322
Query: 520 KTVIKKEEKIEKKEE---KKPEDIKK-EEKDQDELKPGPTNRSRVTKSGSRGMERTVVMD 575
+ + +KEEK+ ++EE +K E I++ EEK ++ K R + R E+ +
Sbjct: 323 EMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQE 382
Query: 576 KS---KGEPVISVKTTSRSKERSSKSQDRKSESKEKRDILSFDKIKEQRERERQRQRERE 632
+ E + + R +E + Q+ K +E++ ++++EQ E+ R++E +
Sbjct: 383 AKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEK--MRRQEEK 440
Query: 633 IRETERR-REREQREREQRLEAFHERKEKARLQRERLQLECQRQRLERERMERERLERER 691
IRE E++ RE+E++ REQ E E++EK Q ++ C+++ +E+ E+ R + E+
Sbjct: 441 IREQEKKIREQEEKIREQE-EMMQEQEEKMGEQEGKM---CEQEAKMQEQEEKMRRQEEK 496
Query: 692 MRVERERRKEQERIHREREELRRQQEQLRYEQERR 726
+R + ++ +EQE RE+EE+ ++QE+ +EQE +
Sbjct: 497 IREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEK 531
Score = 84.3 bits (207), Expect = 5e-16
Identities = 63/216 (29%), Positives = 108/216 (50%), Gaps = 34/216 (15%)
Query: 519 EKTVIKKEEKIEKKEEKKPEDIKKEEKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSK 578
E+ + ++EEKI+++EEK E +K + +++ M R M K
Sbjct: 287 EEKMWRQEEKIQEREEKIQEQEEKIREQEEK------------------MRRQEEMMWEK 328
Query: 579 GEPVISVKTTSRSKERSSKSQDRKSESKEKRDILSFDKIKEQRERERQRQREREIRETER 638
E + + KE + + K +EK RE+E +RQ E +IRE E+
Sbjct: 329 EEKMRRQEEMMWEKEEKIRELEEKMHEQEKI-----------REQEEKRQEEEKIREQEK 377
Query: 639 RREREQREREQRLEAFHERKEKARLQRERLQLECQRQRLERERM----ERERLERERMRV 694
R+E+E + Q E E++EK R Q E +Q + ++ + E+M E + + E+MR
Sbjct: 378 RQEQEAKMWRQE-EKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRR 436
Query: 695 ERERRKEQERIHREREELRRQQEQLRYEQERRPGRR 730
+ E+ +EQE+ RE+EE R+QE++ EQE + G +
Sbjct: 437 QEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQ 472
Score = 76.6 bits (187), Expect = 1e-13
Identities = 79/307 (25%), Positives = 158/307 (51%), Gaps = 22/307 (7%)
Query: 460 EATKCISHLHRT-ELHGRMISVEKAKNEPAG-KKLSDRKECEVKKEKLS---SVDRHHSV 514
EA IS LH + + G + E+A + A KK +DR E+ KE+ + + R+
Sbjct: 147 EARDLISRLHDSWKFAGEL---EQALSAVATQKKKADRYIEELTKERDALSLELYRNTIT 203
Query: 515 EIKIEKTVIKKEEKIEKKEEKKPE---DIKKEEKDQDELKPGPTNRSRVTKSGSRGMERT 571
+ ++++ K +EK++ E +K E ++K+ ++ + K + ++ G E
Sbjct: 204 DEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQ 263
Query: 572 VVMDKSKGEPVISVKTTSRSKERSSKSQDRKSESKEKRDILSFDKIKEQRERERQRQRER 631
V K + + V + +R ++ + R+ E ++R+ +KI+EQ E+ R+ Q E+
Sbjct: 264 SVSAKLQAQ-VEENELWNRLNQQQEEKMWRQEEKIQERE----EKIQEQEEKIRE-QEEK 317
Query: 632 EIRETERRREREQREREQRLEAFHERKEKARLQRERLQLECQRQRLERERMERERLERER 691
R+ E E+E++ R Q E E++EK R E++ + + + E +R E E++ +
Sbjct: 318 MRRQEEMMWEKEEKMRRQE-EMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQE 376
Query: 692 MRVERERR--KEQERIHREREELRRQQEQLRYEQERRPGRRPYDL-DRRDDAYWPEGKRV 748
R E+E + +++E+I RE+EE R+QE++ EQE + G + + ++ ++ E K
Sbjct: 377 KRQEQEAKMWRQEEKI-REQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMR 435
Query: 749 AMEDRYR 755
E++ R
Sbjct: 436 RQEEKIR 442
Score = 76.6 bits (187), Expect = 1e-13
Identities = 54/223 (24%), Positives = 116/223 (52%), Gaps = 14/223 (6%)
Query: 490 KKLSDRKECEVKKEKLSSVDRHHSVEIKI---EKTVIKKEEKIEKKEEKKPEDIKKEEKD 546
+K+ +++E ++EK+ ++ E K+ E+ + ++EEKI ++EE E +K +
Sbjct: 357 EKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQ 416
Query: 547 QDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVKTTSRSKERSSKSQDRKSESK 606
++++ + R E+ +K E + +E+ Q+++ +
Sbjct: 417 EEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQ------EEKIREQEEMMQEQEEKMG 470
Query: 607 EKRDILSFDKIKEQRERERQRQREREIRETERR-REREQREREQRLEAFHERKEKARLQR 665
E+ + + K Q + E+ R++E +IRE E++ RE+E++ REQ E E++EK Q
Sbjct: 471 EQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQE-EMMQEQEEKMWEQE 529
Query: 666 ERLQLECQRQRLERERMERERLERERMRVERERRKEQERIHRE 708
E++ C+++ +E+ E+ R + E+MR + R ++QE +E
Sbjct: 530 EKM---CEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQE 569
Score = 75.1 bits (183), Expect = 3e-13
Identities = 55/244 (22%), Positives = 130/244 (53%), Gaps = 19/244 (7%)
Query: 496 KECEVKKEKLSSVDRHHSVEIKIEKTVIKKEEKIEKKEEKKPED--IKKEEKDQDELKPG 553
KE ++++++ ++ + EK + ++EKI ++EEK+ E+ I+++EK Q++
Sbjct: 328 KEEKMRRQEEMMWEKEEKIRELEEK--MHEQEKIREQEEKRQEEEKIREQEKRQEQEAKM 385
Query: 554 PTNRSRVTKSGSRGMERTVVMDKSKG------EPVISVKTTSRSKERSSKSQDRKSESKE 607
++ + + E+ +M + + E + + + +E + Q+ K +E
Sbjct: 386 WRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQE 445
Query: 608 KRDILSFDKIKEQRE-----RERQRQREREIRETERRREREQREREQRLEAFHERKEKAR 662
K+ +KI+EQ E E+ ++E ++ E E + + ++ + ++ E E+++K R
Sbjct: 446 KKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIR 505
Query: 663 LQRERLQLECQRQRLERERMERERLERERMRVERERRKEQERIHREREELRRQQE-QLRY 721
Q E+++ +++ + +E+ E+ + E+M + E+ +EQE R +EE R+QE +LR
Sbjct: 506 EQEEKIR---EQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQ 562
Query: 722 EQER 725
++E+
Sbjct: 563 QEEK 566
Score = 68.2 bits (165), Expect = 4e-11
Identities = 63/266 (23%), Positives = 133/266 (50%), Gaps = 28/266 (10%)
Query: 478 ISVEKAKNEPAGKKLSDRKECEVKKEKLSSVDRHHSVEIKIEKTVIKKEEKIEKKEEKKP 537
+S+E +N ++L ++ +EKL V+ S +I+ V + + K+E+ + P
Sbjct: 193 LSLELYRNTITDEELKEKNA--KLQEKLQLVESEKS---EIQLNVKELKRKLERAKLLLP 247
Query: 538 EDIKKEEKDQ--DELKPGPTNR----------SRVTKSGSRGMERTVVMDKSKGEPVISV 585
+ + E D EL+ +R+ + M R + + E +
Sbjct: 248 QQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQ 307
Query: 586 KTTSRSKERSSKSQDR----KSESKEKRDILSFDKIKEQRERERQRQREREIRETERRRE 641
+ R +E + Q+ K E +++ + ++K ++ RE E + + +IRE E +R+
Sbjct: 308 EEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQ 367
Query: 642 REQREREQRLEAFHERKEKARLQRERLQLECQRQRLERERMERERLERERMRVERERRKE 701
E++ REQ ++++A++ R+ ++ Q +++ RE+ E + + E+M + E+ E
Sbjct: 368 EEEKIREQE----KRQEQEAKMWRQEEKIREQEEKI-REQEEMMQEQEEKMGEQEEKMWE 422
Query: 702 QERIHREREE-LRRQQEQLRYEQERR 726
QE +E+EE +RRQ+E++R EQE++
Sbjct: 423 QEEEMQEQEEKMRRQEEKIR-EQEKK 447
>gi|22035602 mitogen-activated protein kinase kinase kinase kinase 4
isoform 1 [Homo sapiens]
Length = 1166
Score = 87.4 bits (215), Expect = 6e-17
Identities = 68/241 (28%), Positives = 117/241 (48%), Gaps = 14/241 (5%)
Query: 542 KEEKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISV---KTTSRSKERSSKS 598
K+ D+ K G + + SGS E V + + +++V T R R +
Sbjct: 303 KDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQE 362
Query: 599 QDRKSESKEKRDILSFDKIKEQRERERQ----RQREREIRETERRREREQREREQRLEAF 654
+SE+ ++ +L +++EQ E +RQ RQ+ E ++ +RRR EQ+ RE+
Sbjct: 363 NKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQ 422
Query: 655 HERKEKARLQRERLQLECQRQRLERERMERERLERERMRVERERRKEQERIHREREELRR 714
ER+++ R Q E+ +LE + +R +E ER R E E+ RVER EQE I R+ EE +R
Sbjct: 423 QEREQRRREQEEKRRLE-ELERRRKEEEERRRAEEEKRRVER----EQEYIRRQLEEEQR 477
Query: 715 QQEQLRYEQERRPGRRPYDLDRRDDAYWPEGKRVAMEDRYRADFPRPDHRFHDFDHRDRG 774
E L+ + + +D RR + ++R + F P+ + H ++ DR
Sbjct: 478 HLEVLQQQLLQEQAMLLHD-HRRPHPQHSQQPPPPQQERSKPSFHAPEPKAH-YEPADRA 535
Query: 775 Q 775
+
Sbjct: 536 R 536
Score = 54.3 bits (129), Expect = 5e-07
Identities = 46/157 (29%), Positives = 81/157 (51%), Gaps = 17/157 (10%)
Query: 616 KIKEQRERERQRQREREIRETERRREREQREREQRLEAFHE-----------RKEKARLQ 664
++K+ +R R+++ E++ E E E+ E E R++ RLQ
Sbjct: 301 QLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQ 360
Query: 665 RERLQLE--CQRQRLERERMERERLERER-MRVERERRKEQERIHRER-EELRRQQEQLR 720
+E + +RQ+L +E+ RE+ E +R + ER++R EQ++ R R EE +R++ + R
Sbjct: 361 QENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREAR 420
Query: 721 YEQERRPGRRPYDLDRRDDAYWPEGKRVAMEDRYRAD 757
+QER RR + RR + E +R E+R RA+
Sbjct: 421 RQQEREQRRREQEEKRRLEEL--ERRRKEEEERRRAE 455
>gi|239757964 PREDICTED: hypothetical protein [Homo sapiens]
Length = 290
Score = 87.0 bits (214), Expect = 7e-17
Identities = 54/207 (26%), Positives = 117/207 (56%), Gaps = 7/207 (3%)
Query: 524 KKEEKIEKKEEKKPEDIKKEEKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVI 583
++ +++ +K EK+ + +K ++++ K TNR+R + + +ER +K KG
Sbjct: 79 RERDRVREKTEKERDRDRKRDRERRR-KEKETNRNRDREKQTE-IERDREREKQKGRERE 136
Query: 584 SVKTTSRSKERSSKSQDRKSESKEKRDILSFDKIKEQRERERQRQREREIRETERRRERE 643
+ R ++R + ++R+ ++++ RD + + +R+RER++Q+ERE R+
Sbjct: 137 RDRGRERERDRD-REKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDT 195
Query: 644 QREREQRLEAFHERKEKARLQRER-LQLECQRQ---RLERERMERERLERERMRVERERR 699
++ERE++ + +R+ K + +R+R E +R+ R ER+R ER+R R +E R
Sbjct: 196 EKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEER 255
Query: 700 KEQERIHREREELRRQQEQLRYEQERR 726
K++ + R++E +++E+ R E ++R
Sbjct: 256 KKERKKERKKERKEKKKEEKRREDKKR 282
Score = 77.4 bits (189), Expect = 6e-14
Identities = 67/266 (25%), Positives = 115/266 (43%), Gaps = 23/266 (8%)
Query: 564 GSRGMERTVVMDKSKGEPVISVKTTSRSKERSSKSQDRKSESKEKRDILSFDKIKEQRER 623
G+ +E T+ +D S+G S ++ K D +E+ + + + R+R
Sbjct: 37 GTLWVEVTIPLDFSRGRLGSQESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDR 96
Query: 624 ERQRQREREIRETERRRERE-----QREREQRLEAFHERKEKARLQRERLQLECQRQRLE 678
+R R+R R+ +ET R R+RE +R+RE+ + ER+ +RER + R++
Sbjct: 97 KRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERER---DRDREKER 153
Query: 679 RERMERERLERERMRVERERRKEQER-IHREREELRRQQEQLRYEQERRPGRRPYDLDRR 737
+ E++R + ERER +E+E+ RE E R +Q E+ER+ R + DR+
Sbjct: 154 ERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDR---ERDRQ 210
Query: 738 DDAYWPEGKRVAMEDRYRADFPRPDHRFHDFDHRDRGQYQDHAIDRREGSRPMMGDHRDG 797
+ E D R R RDRG+ +D DR+E + R
Sbjct: 211 RKTQTERQRETDREGERETDRRRERQR-----DRDRGKERDRERDRKEERKKERKKERKK 265
Query: 798 QHYGDDRHGHGGPPERHGRDSRDGWG 823
+ + E+ D + WG
Sbjct: 266 ERKEKKKE------EKRREDKKRKWG 285
Score = 66.6 bits (161), Expect = 1e-10
Identities = 56/200 (28%), Positives = 102/200 (51%), Gaps = 21/200 (10%)
Query: 481 EKAKNEPAGKKLSDRKECEVKKEKLSSVDRHHSVEIKI----EKTVIKKEEKIEKKEEKK 536
EK + E + DR+ +KE + DR EI+ EK ++ E+ +E ++
Sbjct: 86 EKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERER 145
Query: 537 PEDIKKE-----EKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVKTTSRS 591
D +KE EKD+D + T R R + + ER D+ + + T +
Sbjct: 146 DRDREKERERQTEKDRDGQRETETERER-DREREKQKERETERDRDRQ------RDTEKE 198
Query: 592 KERSS-KSQDRKSESKEKRDILSFDKIKEQRERERQRQREREIRETERRRER---EQRER 647
+ER + + +DR+ +++ +R + + + + +R R+RQR+R+ R ER RER E+R++
Sbjct: 199 RERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRD-RGKERDRERDRKEERKK 257
Query: 648 EQRLEAFHERKEKARLQRER 667
E++ E ERKEK + ++ R
Sbjct: 258 ERKKERKKERKEKKKEEKRR 277
Score = 35.4 bits (80), Expect = 0.26
Identities = 29/152 (19%), Positives = 64/152 (42%), Gaps = 26/152 (17%)
Query: 482 KAKNEPAGKKLSDRKECEVKKEKLSSVDRHHSVEIKIEKTVIKKEEKIEKKEEKKPEDIK 541
+ + G++ ++ E ++E+ + DR E + E+ ++ EK +++E ++ D +
Sbjct: 133 RERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQ 192
Query: 542 KE---------EKDQDELKPGPTNRSRVT---------------KSGSRGMERTVVMDKS 577
++ ++++D + T R R T + RG ER ++
Sbjct: 193 RDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERD--RERD 250
Query: 578 KGEPVISVKTTSRSKERSSKSQDRKSESKEKR 609
+ E + R KER K ++ K +KR
Sbjct: 251 RKEERKKERKKERKKERKEKKKEEKRREDKKR 282
>gi|22035604 mitogen-activated protein kinase kinase kinase kinase 4
isoform 2 [Homo sapiens]
Length = 1320
Score = 86.3 bits (212), Expect = 1e-16
Identities = 57/189 (30%), Positives = 97/189 (51%), Gaps = 8/189 (4%)
Query: 542 KEEKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISV---KTTSRSKERSSKS 598
K+ D+ K G + + SGS E V + + +++V T R R +
Sbjct: 303 KDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQE 362
Query: 599 QDRKSESKEKRDILSFDKIKEQRERERQ----RQREREIRETERRREREQREREQRLEAF 654
+SE+ ++ +L +++EQ E +RQ RQ+ E ++ +RRR EQ+ RE+
Sbjct: 363 NKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQ 422
Query: 655 HERKEKARLQRERLQLECQRQRLERERMERERLERERMRVERERRKEQERIHREREELRR 714
ER+++ R Q E+ +LE + +R +E ER R E E+ RVERE+ + ++ E+ L
Sbjct: 423 QEREQRRREQEEKRRLE-ELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEV 481
Query: 715 QQEQLRYEQ 723
Q+QL EQ
Sbjct: 482 LQQQLLQEQ 490
Score = 71.2 bits (173), Expect = 4e-12
Identities = 73/307 (23%), Positives = 137/307 (44%), Gaps = 28/307 (9%)
Query: 509 DRHHSVEIK--IEKTVIKKEEKIEKKEEKKPEDIKKEEKDQDELKPGPTNRSRVTKSGSR 566
+R +++K I++T K+ EK E + E + ++EE + E +P + R
Sbjct: 295 ERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRR 354
Query: 567 GMERTVVMDKSKGEPVISVKTTSRSKERSSKS---------QDRKSESKEKRDILSFDKI 617
R +K + E + + + R + Q R + KE+R L ++
Sbjct: 355 DFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLE-EQQ 413
Query: 618 KEQRERERQRQREREIRETERRREREQREREQRLEAFHERKEKARLQRERLQLECQRQRL 677
+ +RE RQ++RE+ RE E +R E+ ER ++ E R E+ + + ER Q +RQ
Sbjct: 414 RREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLE 473
Query: 678 ERER----MERERLERERMRVERERRKEQERIHREREELRR--QQEQLRYEQERRPGRRP 731
E +R ++++ L+ + M +E R+ +E HR+ E L+R QQEQ + RRP
Sbjct: 474 EEQRHLEVLQQQLLQEQAMLLECRWREMEE--HRQAERLQRQLQQEQAYLLSLQHDHRRP 531
Query: 732 YDLDRRDDAYWPEGKRVAMEDRYRADFPRPDHRFHDFDHRDRGQYQDHAIDRREGSRPMM 791
+ + ++R + F P+ + H ++ DR + + + S P
Sbjct: 532 HPQHSQQPP-------PPQQERSKPSFHAPEPKAH-YEPADRAREVEDRFRKTNHSSPEA 583
Query: 792 GDHRDGQ 798
+ G+
Sbjct: 584 QSKQTGR 590
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 85.9 bits (211), Expect = 2e-16
Identities = 98/349 (28%), Positives = 156/349 (44%), Gaps = 43/349 (12%)
Query: 470 RTELHG--RMISVEKAKNEPAGK---KLSDRKECEVKKEKLSSVDRHHSVEIKIEKTVIK 524
RTE+ R S + +N+ G+ ++ + E + + S +D H S
Sbjct: 540 RTEIRNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNS--------N 591
Query: 525 KEEKIEKKEEKKPEDIKKEEKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVIS 584
+ E + D E ++D+ + R + G R D+ P I
Sbjct: 592 YHDSWETRSSYPERDRYPERDNRDQARDSSFER----RHGERDRRDNRERDQRPSSP-IR 646
Query: 585 VKTTSRSKERSSKSQDRKSESKEKRDILSFDKIKEQRERERQRQREREIRETERRRERE- 643
+ + ER + ++R+ + + R D+ +R+RER+R RERE RE ER R+RE
Sbjct: 647 HQGRNDELERDERREERRVDRVDDRR----DERARERDRERERDRERE-RERERERDRER 701
Query: 644 QREREQRLEAFHERKEKARLQRERLQLECQRQRLERERMERER---LERERMRVERERRK 700
++ERE E ER+ + +R+R + + ERER ERER ERER R ERER +
Sbjct: 702 EKERELERERAREREREREKERDRERDRDRDHDRERER-ERERDREKEREREREERERER 760
Query: 701 EQERIHREREELRRQQEQLRYEQERRPGRRPYDLDR-RDDAYWPEGKRVAMEDRYRADFP 759
E+ER RERE R ++ ++ER R D D+ RDD E + EDR P
Sbjct: 761 ERER-ERERERERERERARERDKERERQRDWEDKDKGRDDR--REKREEIREDRN----P 813
Query: 760 RPDHRFHDFDHRDRGQYQDHAIDRREGSRPMMGDH---RDGQHYGDDRH 805
R H + + + +Y++ S +H D + GDD++
Sbjct: 814 RDGHD----ERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKN 858
Score = 66.2 bits (160), Expect = 1e-10
Identities = 59/189 (31%), Positives = 97/189 (51%), Gaps = 28/189 (14%)
Query: 555 TNRSRVTKSGSRGMERTVVMDKS-----------KGEPVISVKTTSRSKERSSKSQDRKS 603
+ R RV SGSR E+T ++ + +GEP ++TS ++ S R+S
Sbjct: 1222 SGRKRVLHSGSRDREKTKSLEITGERKSRIDQLKRGEPS---RSTSSDRQDSRSHSSRRS 1278
Query: 604 ESKEKRDILSFDKIKEQRERERQRQREREIRETERRREREQREREQRLEAFHERKEKARL 663
+ R + S + R+R ++R R RE ER R R+ R+RE +A ++
Sbjct: 1279 SPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERER-RDTRQREWDRDA--DKDWPRNR 1335
Query: 664 QRERLQLECQRQRLERERMERERLERERMR-----VERERRKEQERIHR--EREELRRQQ 716
R+RL+ +R+R ERER +R L+RER R VER+R ++++R + E ++R +
Sbjct: 1336 DRDRLR---ERER-ERERDKRRDLDRERERLISDSVERDRDRDRDRTFESSQIESVKRCE 1391
Query: 717 EQLRYEQER 725
+L E ER
Sbjct: 1392 AKLEGEHER 1400
Score = 61.2 bits (147), Expect = 4e-09
Identities = 90/411 (21%), Positives = 153/411 (37%), Gaps = 53/411 (12%)
Query: 524 KKEEKIEKKEEKKPEDIKKEEKD---QDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGE 580
K++ K++ + E+K D K +D Q E + P + S + S R G
Sbjct: 281 KEKYKVKDRIEEKTRDGKDRGRDFERQREKRDKPRSTSPAGQHHSPISSRHHSSSSQSGS 340
Query: 581 PVISVKTTSRSKERSSKSQDR-------KSESKEKRDILSFDKIKEQRERERQRQREREI 633
+ + R K S S R +S S LS + K+ R R RE+
Sbjct: 341 SIQRHSPSPRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPPRHRSPMREKGR 400
Query: 634 RETERRREREQREREQR--LEAFHERKEKARLQRERLQLECQRQRLERERMERERLERER 691
+ ER + R E+R +R++ +R +RE Q + + +R R+ +R
Sbjct: 401 HDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGRDRRD 460
Query: 692 MRVERERRKEQE----RIHREREELRRQQEQLRYEQERRPGRRPY--------DLDRRDD 739
R R+RR+ ++ R RE + R ++ R ++ R R + D R++D
Sbjct: 461 ARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKED 520
Query: 740 AYWPEGKRVAMEDRYRADFPRPDHRFHDFDHRDRGQYQDHAIDRREGSRP---------- 789
Y PE R + R + R + R ++ + R + ++ + R G P
Sbjct: 521 TY-PEESRSYGRNHLREESSRTEIR-NESRNESRSEIRNDRMGRSRGRVPELPEKGSRGS 578
Query: 790 ---MMGDHRDGQHYGDDRHGHGGPPERH---GRDSRD-----------GWGGYGSDKRLS 832
+ H +Y D PER RD+RD G ++
Sbjct: 579 RGSQIDSHSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERD 638
Query: 833 EGRGLPPPPRGGRDWGEHNQRLEEHQARAWQGAMDAGAASREHARWQGGER 883
+ P +G D E ++R EE + D A R+ R + ER
Sbjct: 639 QRPSSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDRERERDRER 689
Score = 55.8 bits (133), Expect = 2e-07
Identities = 54/268 (20%), Positives = 125/268 (46%), Gaps = 17/268 (6%)
Query: 476 RMISVEKAKNEPAGKKLSDR-KECEVKKEKLSSVDRHHSVEIKIEKTVIKKEEKIEKKEE 534
R+ V+ ++E A ++ +R ++ E ++E+ DR E ++E+ ++ E+ +KE
Sbjct: 664 RVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERAREREREREKER 723
Query: 535 KKPEDIKKE-----EKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVKTTS 589
+ D ++ E++++ + R R + R ER ++ + +
Sbjct: 724 DRERDRDRDHDRERERERERDREKEREREREERERERERERERERERERERERARERDKE 783
Query: 590 RSKERSSKSQDR-KSESKEKRDILSFDKIKE--QRERERQRQREREIRETERRREREQRE 646
R ++R + +D+ + + +EKR+ + D+ ER+ +++ E + R+ + +RE
Sbjct: 784 RERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRRE 843
Query: 647 REQRLEAFH---ERKEKARLQRERLQLECQR----QRLERERMERERLE-RERMRVERER 698
+A++ ++ EK RL + ++ + R L +R R + E R+ R E R
Sbjct: 844 HSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKPERKESSR 903
Query: 699 RKEQERIHREREELRRQQEQLRYEQERR 726
R E++ + + + +Q+EQ + R
Sbjct: 904 RYEEQELKEKVSSVDKQREQTEILESSR 931
Score = 52.8 bits (125), Expect = 2e-06
Identities = 91/375 (24%), Positives = 141/375 (37%), Gaps = 50/375 (13%)
Query: 516 IKIEKTVIKKEEKIEKKEEKKPEDIKKEEKDQDELKPGPTNRSRVTKSGSRGMERTVVMD 575
+K+E+ ++K E+I K+E PE ++ +L P P+ R + +KS R
Sbjct: 178 MKLEQENMEKREEIIIKKEVSPEVVR------SKLSPSPSLR-KSSKSPKRKSSPKSSSA 230
Query: 576 KSKGEPVISVKTTSRSKERSSKSQDRKSESKE--------KRDILSFDKIKEQ-----RE 622
K +V + ++R+SK+ K + DI K KE+ R
Sbjct: 231 SKKDRKTSAVSSPLLDQQRNSKTNQSKKKGPRTPSPPPPIPEDIALGKKYKEKYKVKDRI 290
Query: 623 RERQRQREREIRETERRREREQREREQRLEAFHERKEKAR-----------LQRERLQLE 671
E+ R + R+ ER+RE+ + R H +R +QR
Sbjct: 291 EEKTRDGKDRGRDFERQREKRDKPRSTSPAGQHHSPISSRHHSSSSQSGSSIQRHSPSPR 350
Query: 672 CQR------QRLERERMERERLERERMRVERERRKEQERIHRE--REELRRQQEQLRYEQ 723
+R QR + R + +RK+ HR RE+ R E+
Sbjct: 351 RKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHDHERTSQSH 410
Query: 724 ERRPGRRPYDLDRRDDAYWPEGKRVAMEDRYRADFPRPDHRFHDFDHRDRGQYQDHAIDR 783
+RR RR +RD +R +D+ + R D D RDR +D DR
Sbjct: 411 DRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDR--EPRDGRDRRDARD-TRDR 467
Query: 784 RE--GSRPMMGDHRDGQHYGDDRHGHGGPPE-RHGRDSRDGWGGYGSDKRLSEGRGLPPP 840
RE SR M D R+ + Y D P + R RD+ D G D E
Sbjct: 468 RELRDSRDMR-DSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKE----DTY 522
Query: 841 PRGGRDWGEHNQRLE 855
P R +G ++ R E
Sbjct: 523 PEESRSYGRNHLREE 537
Score = 51.2 bits (121), Expect = 4e-06
Identities = 68/283 (24%), Positives = 115/283 (40%), Gaps = 30/283 (10%)
Query: 517 KIEKTVIKKEEK----IEKKEEKKPEDIKKEEKDQDELKPGPTNRSRVT---KSGSRGME 569
K +T ++K E IE + +KP D +K L +NRS + +S S
Sbjct: 1159 KCHRTRVEKVETPHVTIEDAQHRKPMD----QKRSSSLGSNRSNRSHTSGRLRSPSNDSA 1214
Query: 570 RTVVMDKSKGEPVISVKTTSRSKERSSKSQDRKSESKEKRDILSFDKIKEQRERERQRQR 629
D+S + V+ + R K +KS + E K + D L + +RQ R
Sbjct: 1215 HRSGDDQSGRKRVLHSGSRDREK---TKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSR 1271
Query: 630 EREIRETERRREREQREREQRLEAFHERKEKARLQRERLQLECQRQRLERERMERER--- 686
R + +R+ R ++ +E+ R + +R E +R+R + + E +R
Sbjct: 1272 SHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDR---ERERERRDTRQREWDRDAD 1328
Query: 687 --LERERMRVERERRKEQERIHREREELRRQQEQLRYEQERRPGRRPYDLDRRDDAYWPE 744
R R R +R R +E+ER +R +L R++E+L + R D DR D + E
Sbjct: 1329 KDWPRNRDR-DRLRERERERERDKRRDLDRERERLISDSVER------DRDRDRDRTF-E 1380
Query: 745 GKRVAMEDRYRADFPRPDHRFHDFDHRDRGQYQDHAIDRREGS 787
++ R A R + RD +D+ GS
Sbjct: 1381 SSQIESVKRCEAKLEGEHERDLESTSRDSLALDKERMDKDLGS 1423
Score = 48.1 bits (113), Expect = 4e-05
Identities = 57/238 (23%), Positives = 105/238 (44%), Gaps = 29/238 (12%)
Query: 480 VEKAKNEPAGKKLSDRKECEVKKEKLSSVDRHHSVEIKIEKTVIKKEEKIEKKEEKKPED 539
+++ ++ G S+R + S+ H S + + + + ++++ K E
Sbjct: 1184 MDQKRSSSLGSNRSNRSHTSGRLRSPSNDSAHRSGDDQSGRKRVLHSGSRDREKTKSLEI 1243
Query: 540 IKKEEKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVKTTS-------RSK 592
+ + D+LK G +RS S R R+ +S E V + S R +
Sbjct: 1244 TGERKSRIDQLKRGEPSRST---SSDRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQ 1300
Query: 593 ERSSKSQDRKSESKEKRDILSFDKIKE-------QRERERQRQREREIRETERR---RER 642
ER DR+ E +E+RD + ++ R+R+R R+RERE +RR RER
Sbjct: 1301 ERDRYEHDRERE-RERRDTRQREWDRDADKDWPRNRDRDRLRERERERERDKRRDLDRER 1359
Query: 643 E-------QREREQRLEAFHERKEKARLQRERLQLECQRQR-LERERMERERLERERM 692
E +R+R++ + E + ++R +LE + +R LE + L++ERM
Sbjct: 1360 ERLISDSVERDRDRDRDRTFESSQIESVKRCEAKLEGEHERDLESTSRDSLALDKERM 1417
Score = 40.0 bits (92), Expect = 0.010
Identities = 41/189 (21%), Positives = 79/189 (41%), Gaps = 22/189 (11%)
Query: 484 KNEPAGKKLSDRKECEVKKEKLSSVDRHHSVEIKI----EKTVIKKEEKIEKKEEKKPE- 538
+ EP+ SDR++ + SS + V + + +++ ++ E E++ E
Sbjct: 1256 RGEPSRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERER 1315
Query: 539 -DIKKEEKDQDELKPGPTNRSRVT-KSGSRGMERTVVMDKSKGEPVISVKTTSRSKER-- 594
D ++ E D+D K P NR R + R ER D + + + R ++R
Sbjct: 1316 RDTRQREWDRDADKDWPRNRDRDRLRERERERERDKRRDLDRERERLISDSVERDRDRDR 1375
Query: 595 ----------SSKSQDRKSESKEKRDILSFDKIKEQRERERQRQREREIRETERRREREQ 644
S K + K E + +RD+ S + ++ER ++++ + E +
Sbjct: 1376 DRTFESSQIESVKRCEAKLEGEHERDLESTSRDSLALDKERM---DKDLGSVQGFEETNK 1432
Query: 645 REREQRLEA 653
ER + LEA
Sbjct: 1433 SERTESLEA 1441
Score = 37.0 bits (84), Expect = 0.088
Identities = 31/129 (24%), Positives = 61/129 (47%), Gaps = 16/129 (12%)
Query: 586 KTTSRSKER-SSKSQDRKSESKEKRDILSFDKIKEQRERERQRQREREIRETERRREREQ 644
+ T +ER +K QD +E +++ S ++ +E R R RE+E + + R E
Sbjct: 80 RPTGDLRERMKNKRQDVDTEPQKRNTEESSSPVR--KESSRGRHREKEDIKITKERTPES 137
Query: 645 REREQRLEAFHERKEKARLQRE---RLQLECQRQRLERERMERERLERERMRVERERRKE 701
E E + + + + L LE M+R++++RE M++E+E ++
Sbjct: 138 EEENVEWETNRDDSDNGDINYDYVHELSLE----------MKRQKIQRELMKLEQENMEK 187
Query: 702 QERIHRERE 710
+E I ++E
Sbjct: 188 REEIIIKKE 196
Score = 33.1 bits (74), Expect = 1.3
Identities = 25/112 (22%), Positives = 51/112 (45%), Gaps = 18/112 (16%)
Query: 623 RERQRQREREIRETERRREREQREREQRLEAF---HERKEKARLQRERLQLECQRQRLER 679
RER + + +++ ++R E+ R E+ H KE ++ +ER E + + +E
Sbjct: 86 RERMKNKRQDVDTEPQKRNTEESSSPVRKESSRGRHREKEDIKITKERTP-ESEEENVEW 144
Query: 680 ERMERER--------------LERERMRVERERRKEQERIHREREELRRQQE 717
E + LE +R +++RE K ++ +REE+ ++E
Sbjct: 145 ETNRDDSDNGDINYDYVHELSLEMKRQKIQRELMKLEQENMEKREEIIIKKE 196
>gi|56549694 enabled homolog isoform a [Homo sapiens]
Length = 591
Score = 85.5 bits (210), Expect = 2e-16
Identities = 60/137 (43%), Positives = 89/137 (64%), Gaps = 10/137 (7%)
Query: 598 SQDRKSESKEKRDILSFDKIKEQRERERQRQR-EREIRETER-RREREQREREQRLEAFH 655
+Q + S+E+ +I ++QR++E +R+R ERE E ER RER +RER +R
Sbjct: 129 AQVQNGPSQEELEIQRRQLQEQQRQKELERERLERERMERERLERERLERERLERERLEQ 188
Query: 656 ERKEKARLQRERLQLECQRQRLER-ERMER-ERLERERMRVERERRKEQERIHREREELR 713
E+ E+ R +RER + +++RLER ER+ER ERL+RER ER+ R+ ER+ RER+E
Sbjct: 189 EQLERERQERERQERLERQERLERQERLERQERLDRERQ--ERQERERLERLERERQERE 246
Query: 714 RQQ----EQLRYEQERR 726
RQ+ EQL +E+ERR
Sbjct: 247 RQEQLEREQLEWERERR 263
Score = 80.1 bits (196), Expect = 9e-15
Identities = 53/138 (38%), Positives = 82/138 (59%), Gaps = 18/138 (13%)
Query: 626 QRQREREIRETERRREREQREREQRLEAFHERKEKARLQRERLQLE-CQRQRLERERMER 684
Q +E E +RR+ +EQ +R++ LE ER E+ R++RERL+ E +R+RLERER+E+
Sbjct: 132 QNGPSQEELEIQRRQLQEQ-QRQKELE--RERLERERMERERLERERLERERLERERLEQ 188
Query: 685 ERLERERMRVERERRKE-------------QERIHREREELRRQQEQLRYEQERRPGRRP 731
E+LERER ER+ R E QER+ RER+E + ++ R E+ER+ R
Sbjct: 189 EQLERERQERERQERLERQERLERQERLERQERLDRERQERQERERLERLERERQERERQ 248
Query: 732 YDLDRRDDAYWPEGKRVA 749
L+ R+ W +R++
Sbjct: 249 EQLE-REQLEWERERRIS 265
Score = 73.6 bits (179), Expect = 8e-13
Identities = 46/113 (40%), Positives = 71/113 (62%), Gaps = 12/113 (10%)
Query: 593 ERSSKSQDRKSESKEKRDILSFDKIKEQRERERQRQREREIRETERRREREQR-EREQRL 651
ER ++R + +R+ L ++++ +R + Q +RER+ RE + R ER++R ER++RL
Sbjct: 157 ERERLERERMERERLERERLERERLERERLEQEQLERERQERERQERLERQERLERQERL 216
Query: 652 EAFH--ERKEKARLQRERLQLECQRQRLERERMERER---LERERMRVERERR 699
E +R+ + R +RERL+ RLERER ERER LERE++ ERERR
Sbjct: 217 ERQERLDRERQERQERERLE------RLERERQERERQEQLEREQLEWERERR 263
Score = 68.9 bits (167), Expect = 2e-11
Identities = 47/112 (41%), Positives = 68/112 (60%), Gaps = 13/112 (11%)
Query: 659 EKARLQRERLQLECQRQRLERERMERERLERERMRVERER----RKEQERIHREREELRR 714
++ +LQ ++ Q E +R+RLERERMERERLERER+ ERER R EQE++ RER+E R
Sbjct: 143 QRRQLQEQQRQKELERERLERERMERERLERERL--ERERLERERLEQEQLERERQERER 200
Query: 715 QQEQLRYE----QERRPGRRPYDLDRRDDAYWPEGKRVAMEDRYRADFPRPD 762
Q+ R E QER + D +R++ E +R+ +R R + R +
Sbjct: 201 QERLERQERLERQERLERQERLDRERQER---QERERLERLERERQERERQE 249
Score = 41.2 bits (95), Expect = 0.005
Identities = 32/133 (24%), Positives = 71/133 (53%), Gaps = 8/133 (6%)
Query: 526 EEKIEKKEEKKPEDIKKEEKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISV 585
+E++E + + E +++E +++ L+ R R+ + +ER + + + +
Sbjct: 137 QEELEIQRRQLQEQQRQKELERERLERERMERERLERER---LERERLERERLEQEQLER 193
Query: 586 KTTSRSKERSSKSQDR--KSESKEKRDILSFDKIKEQ-RERERQRQREREIRETERRRER 642
+ R ++ + Q+R + E E+++ L ++ + Q RER + +RER+ RE + + ER
Sbjct: 194 ERQERERQERLERQERLERQERLERQERLDRERQERQERERLERLERERQERERQEQLER 253
Query: 643 EQR--EREQRLEA 653
EQ ERE+R+ +
Sbjct: 254 EQLEWERERRISS 266
Score = 36.2 bits (82), Expect = 0.15
Identities = 27/77 (35%), Positives = 43/77 (55%), Gaps = 6/77 (7%)
Query: 651 LEAFHERKEKARLQRERLQLECQRQRLERERMERERLERERMRV-ERERRKEQERIHRER 709
LE + ++ L R+ QL Q Q +E LE +R ++ E++R+KE ER ER
Sbjct: 108 LEVLNSQETGPTLPRQNSQLPAQVQN----GPSQEELEIQRRQLQEQQRQKELERERLER 163
Query: 710 EELRRQQ-EQLRYEQER 725
E + R++ E+ R E+ER
Sbjct: 164 ERMERERLERERLERER 180
>gi|39930375 enabled homolog isoform b [Homo sapiens]
Length = 570
Score = 85.5 bits (210), Expect = 2e-16
Identities = 60/137 (43%), Positives = 89/137 (64%), Gaps = 10/137 (7%)
Query: 598 SQDRKSESKEKRDILSFDKIKEQRERERQRQR-EREIRETER-RREREQREREQRLEAFH 655
+Q + S+E+ +I ++QR++E +R+R ERE E ER RER +RER +R
Sbjct: 129 AQVQNGPSQEELEIQRRQLQEQQRQKELERERLERERMERERLERERLERERLERERLEQ 188
Query: 656 ERKEKARLQRERLQLECQRQRLER-ERMER-ERLERERMRVERERRKEQERIHREREELR 713
E+ E+ R +RER + +++RLER ER+ER ERL+RER ER+ R+ ER+ RER+E
Sbjct: 189 EQLERERQERERQERLERQERLERQERLERQERLDRERQ--ERQERERLERLERERQERE 246
Query: 714 RQQ----EQLRYEQERR 726
RQ+ EQL +E+ERR
Sbjct: 247 RQEQLEREQLEWERERR 263
Score = 80.1 bits (196), Expect = 9e-15
Identities = 53/138 (38%), Positives = 82/138 (59%), Gaps = 18/138 (13%)
Query: 626 QRQREREIRETERRREREQREREQRLEAFHERKEKARLQRERLQLE-CQRQRLERERMER 684
Q +E E +RR+ +EQ +R++ LE ER E+ R++RERL+ E +R+RLERER+E+
Sbjct: 132 QNGPSQEELEIQRRQLQEQ-QRQKELE--RERLERERMERERLERERLERERLERERLEQ 188
Query: 685 ERLERERMRVERERRKE-------------QERIHREREELRRQQEQLRYEQERRPGRRP 731
E+LERER ER+ R E QER+ RER+E + ++ R E+ER+ R
Sbjct: 189 EQLERERQERERQERLERQERLERQERLERQERLDRERQERQERERLERLERERQERERQ 248
Query: 732 YDLDRRDDAYWPEGKRVA 749
L+ R+ W +R++
Sbjct: 249 EQLE-REQLEWERERRIS 265
Score = 73.6 bits (179), Expect = 8e-13
Identities = 46/113 (40%), Positives = 71/113 (62%), Gaps = 12/113 (10%)
Query: 593 ERSSKSQDRKSESKEKRDILSFDKIKEQRERERQRQREREIRETERRREREQR-EREQRL 651
ER ++R + +R+ L ++++ +R + Q +RER+ RE + R ER++R ER++RL
Sbjct: 157 ERERLERERMERERLERERLERERLERERLEQEQLERERQERERQERLERQERLERQERL 216
Query: 652 EAFH--ERKEKARLQRERLQLECQRQRLERERMERER---LERERMRVERERR 699
E +R+ + R +RERL+ RLERER ERER LERE++ ERERR
Sbjct: 217 ERQERLDRERQERQERERLE------RLERERQERERQEQLEREQLEWERERR 263
Score = 68.9 bits (167), Expect = 2e-11
Identities = 47/112 (41%), Positives = 68/112 (60%), Gaps = 13/112 (11%)
Query: 659 EKARLQRERLQLECQRQRLERERMERERLERERMRVERER----RKEQERIHREREELRR 714
++ +LQ ++ Q E +R+RLERERMERERLERER+ ERER R EQE++ RER+E R
Sbjct: 143 QRRQLQEQQRQKELERERLERERMERERLERERL--ERERLERERLEQEQLERERQERER 200
Query: 715 QQEQLRYE----QERRPGRRPYDLDRRDDAYWPEGKRVAMEDRYRADFPRPD 762
Q+ R E QER + D +R++ E +R+ +R R + R +
Sbjct: 201 QERLERQERLERQERLERQERLDRERQER---QERERLERLERERQERERQE 249
Score = 41.2 bits (95), Expect = 0.005
Identities = 32/133 (24%), Positives = 71/133 (53%), Gaps = 8/133 (6%)
Query: 526 EEKIEKKEEKKPEDIKKEEKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISV 585
+E++E + + E +++E +++ L+ R R+ + +ER + + + +
Sbjct: 137 QEELEIQRRQLQEQQRQKELERERLERERMERERLERER---LERERLERERLEQEQLER 193
Query: 586 KTTSRSKERSSKSQDR--KSESKEKRDILSFDKIKEQ-RERERQRQREREIRETERRRER 642
+ R ++ + Q+R + E E+++ L ++ + Q RER + +RER+ RE + + ER
Sbjct: 194 ERQERERQERLERQERLERQERLERQERLDRERQERQERERLERLERERQERERQEQLER 253
Query: 643 EQR--EREQRLEA 653
EQ ERE+R+ +
Sbjct: 254 EQLEWERERRISS 266
Score = 36.2 bits (82), Expect = 0.15
Identities = 27/77 (35%), Positives = 43/77 (55%), Gaps = 6/77 (7%)
Query: 651 LEAFHERKEKARLQRERLQLECQRQRLERERMERERLERERMRV-ERERRKEQERIHRER 709
LE + ++ L R+ QL Q Q +E LE +R ++ E++R+KE ER ER
Sbjct: 108 LEVLNSQETGPTLPRQNSQLPAQVQN----GPSQEELEIQRRQLQEQQRQKELERERLER 163
Query: 710 EELRRQQ-EQLRYEQER 725
E + R++ E+ R E+ER
Sbjct: 164 ERMERERLERERLERER 180
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 85.5 bits (210), Expect = 2e-16
Identities = 63/288 (21%), Positives = 150/288 (52%), Gaps = 26/288 (9%)
Query: 481 EKAKNEPAGKKLSDRKECEVKKEKLSSVDR---HHSVEIKIEKTVIKKEEKI---EKKEE 534
E+ + E ++L ++KE ++EK+ + +I+ ++ + +E+K+ EK E
Sbjct: 424 EQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMRE 483
Query: 535 KKPEDIKKEEKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVKTTSRSKER 594
++ + ++EEK +D+ + R+ + R E+ M + K ++
Sbjct: 484 QEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQK----------KMWQQE 533
Query: 595 SSKSQDRKSESKEKRDILSFDKIKEQRERERQRQREREIRETERRREREQREREQRLEAF 654
+++K++ +EK+ ++D+ ++ RE ER R+RE+++RE E ++ + +++ E
Sbjct: 534 EKMREEKKTQEQEKK---TWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKM 590
Query: 655 HERKEKARLQRERLQLECQRQRLERERM-----ERERLERERMRVERERR--KEQERIHR 707
E++EK Q E++Q + ++ + E+M E + E+E M E+E + +++E++
Sbjct: 591 REQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWE 650
Query: 708 EREELRRQQEQLRYEQERRPGRRPYDLDRRDDAYWPEGKRVAMEDRYR 755
+ E++R Q+E++R ++E+ G+ ++ + E K E++ R
Sbjct: 651 QEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMR 698
Score = 82.0 bits (201), Expect = 2e-15
Identities = 62/248 (25%), Positives = 130/248 (52%), Gaps = 17/248 (6%)
Query: 510 RHHSVEIKIEKTVIKKEEKIEKKEEKKPEDIKKEEKDQDELKPGPTNRSRVTKSGSRGME 569
R ++ +K + ++EEK+ +EEKK ++ +K+ DQ+E K R R + R E
Sbjct: 517 REKEERMREQKKMWQQEEKM--REEKKTQEQEKKTWDQEE-KMREEERMREREKKMREEE 573
Query: 570 RTVVMDKSKGEPVISVKTTSRSKERSSKSQDRKSESKEKRDILSFDKIKEQRERERQRQR 629
M + + E + + R +E Q+ K + +E++ +K+ EQ E ++ +++
Sbjct: 574 E---MMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQ 630
Query: 630 EREIRETERRREREQREREQRLEAFHERKEKARLQRERLQLECQRQRLERERM----ERE 685
E + E E + + ++ + ++ E E++EK R Q E++Q + ++ R + E+M E+
Sbjct: 631 EEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKM 690
Query: 686 RLERERMRVERERR--KEQERIHRE-----REELRRQQEQLRYEQERRPGRRPYDLDRRD 738
R + E+MR + E+ +E++ +E +EE+R ++E++R ++E+ R P +R
Sbjct: 691 REQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEERCS 750
Query: 739 DAYWPEGK 746
+ P K
Sbjct: 751 EPCLPPSK 758
Score = 80.5 bits (197), Expect = 7e-15
Identities = 65/311 (20%), Positives = 153/311 (49%), Gaps = 37/311 (11%)
Query: 510 RHHSVEIKIEKTVIKKEEKIEKKEEKKPEDIKKEEKDQDELKPGPTNRSRVTKSGSRGME 569
R +++ ++ ++++EK +++EK+ + +KE ++Q +L+ ++ + + E
Sbjct: 265 REQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLRE---QEEQMQEQEEKMWE 321
Query: 570 RTVVMDKSKGEPVISVKTTSRSKERSSKSQDRKSESKEKRDILSFDKIKEQRERERQRQR 629
+ M + + E + + +E+ + Q++K +E+R ++++E+ ER R++++
Sbjct: 322 QEEKM-REQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEK 380
Query: 630 ----EREIRETERRREREQREREQRLEAFHERKEKARLQRERL----QLECQRQRLERER 681
E +++E ER RERE++ RE+ E E++EK + Q E + + E Q+QRL ++
Sbjct: 381 MWEQEEKMQEEERIREREKKMREEE-ETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQK 439
Query: 682 ---MERERLERERMRV---------------------ERERRKEQERIHREREELRRQQE 717
E+E+++ + ++ +E+ +EQE E+EE R QE
Sbjct: 440 EKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQE 499
Query: 718 QLRYEQERRPGRRPYDLDRRDDAYWPEGKRVAMEDRYRADFPRPDHRFHDFDHRDRGQYQ 777
Q ++QE R + L +++ + K E++ R + + +D ++ + +
Sbjct: 500 QKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREE 559
Query: 778 DHAIDRREGSR 788
+ +R + R
Sbjct: 560 ERMREREKKMR 570
Score = 79.0 bits (193), Expect = 2e-14
Identities = 68/296 (22%), Positives = 152/296 (51%), Gaps = 31/296 (10%)
Query: 486 EPAGKKLSDRKECEVKKEKLSSVDRHHSVEIKIEKTVIKKEEKIEKKEEKK----PEDIK 541
E ++ + +E E K K ++ ++ ++++E+ +++EK+ ++++
Sbjct: 234 EEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELR 293
Query: 542 KEEKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVKTTSRSKERSSKSQDR 601
++EK+ E K ++ + + E+ M + + E + + +E+ + Q++
Sbjct: 294 EQEKELREQKKLREQEEQMQEQEEKMWEQEEKM-REQEEKMWRQEERLWEQEKQMREQEQ 352
Query: 602 KSESKEKRDILSFDKIKEQRERERQRQR----EREIRETERRREREQREREQRLEAFHER 657
K +E+R ++++E+ ER R++++ E +++E ER RERE++ RE+ E E+
Sbjct: 353 KMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEE-ETMREQ 411
Query: 658 KEKARLQRERL----QLECQRQRLERERMERERL-ERERMRVERERRKEQERIHREREEL 712
+EK + Q E + + E Q+QRL ++E+L E+E+M+ + E+ EQE R++EE+
Sbjct: 412 EEKMQKQEENMWEQEEKEWQQQRLPE---QKEKLWEQEKMQEQEEKIWEQEEKIRDQEEM 468
Query: 713 ------------RRQQEQLRYEQERRPGRRPYDLDRRDDAYWPEGKRV-AMEDRYR 755
R+QE +EQE + + + +++ W + +R+ E+R R
Sbjct: 469 WGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMR 524
Score = 78.6 bits (192), Expect = 3e-14
Identities = 67/268 (25%), Positives = 134/268 (50%), Gaps = 30/268 (11%)
Query: 491 KLSDRKECEVKKEKLSSVDRHHSVEIKIEKTVIKKEEKIEKKEEKKPEDIKKEEKDQDEL 550
K +DR E+ KE+ ++ +++ + I EE ++KK + E ++ E ++ E+
Sbjct: 155 KKADRYIEELTKER-------DALSLELYRNTITNEE-LKKKNAELQEKLRLAESEKSEI 206
Query: 551 KPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVKTTSRS---KERSSKSQDRKSESKE 607
+ K R +ER + P + T +E + Q++K +E
Sbjct: 207 QLN-------VKELKRKLERAKFL-----LPQVQTNTLQEEMWRQEEELREQEKKIRKQE 254
Query: 608 KRDILSFDKIKEQRERERQRQREREIRETERRREREQREREQRLEAFHERKEKARLQRER 667
++ ++++EQ + R+ Q E+ R+ +R RE+E+ REQ E +E+ +L+ +
Sbjct: 255 EKMWRQEERLREQEGKMRE-QEEKMRRQEKRLREQEKELREQE----KELREQKKLREQE 309
Query: 668 LQLECQRQRLERERMERERLERERMRVERERRKEQERIHREREELRRQQEQLRYEQERRP 727
Q++ Q +++ E+ E+ R + E+M + ER EQE+ RE+E+ R QE+ +EQ+ R
Sbjct: 310 EQMQEQEEKM-WEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERL 368
Query: 728 GRRPYDLDRRDDAYWPEGKRVAMEDRYR 755
R + R + W + +++ E+R R
Sbjct: 369 -REKEERMREQEKMWEQEEKMQEEERIR 395
Score = 67.8 bits (164), Expect = 5e-11
Identities = 51/204 (25%), Positives = 111/204 (54%), Gaps = 21/204 (10%)
Query: 587 TTSRSKERSSKSQD--RKSESKEKRDILSFDKIKEQRERER---QRQREREIRETERRRE 641
T K+++++ Q+ R +ES++ L+ ++K + ER + + + ++E R+E
Sbjct: 181 TNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQE 240
Query: 642 REQREREQRLEAFHERKEKARLQRERLQLECQRQRLERERMERERLERERMRVERERRKE 701
E RE+E+++ +++EK Q ERL+ +++ RE+ E+ R + +R+R + + +E
Sbjct: 241 EELREQEKKI---RKQEEKMWRQEERLR---EQEGKMREQEEKMRRQEKRLREQEKELRE 294
Query: 702 QERIHREREELRRQQEQLR------YEQERRPGRRPYDLDRRDDAYWPEGKRVAMEDRYR 755
QE+ RE+++LR Q+EQ++ +EQE + + + R+++ W + K++ +++
Sbjct: 295 QEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKM 354
Query: 756 AD----FPRPDHRFHDFDHRDRGQ 775
D D R + + R R Q
Sbjct: 355 RDQEERMWEQDERLREKEERMREQ 378
Score = 66.6 bits (161), Expect = 1e-10
Identities = 70/320 (21%), Positives = 149/320 (46%), Gaps = 37/320 (11%)
Query: 472 ELHGRMISVEKAKNEPAGKKLSDRKECEVKKEKLSSVDRHHSVEIKI---EKTVIKKEEK 528
E +M EK E + KE +K+ ++ E K+ E+ + ++EEK
Sbjct: 273 EQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEK 332
Query: 529 IEKKEEKKPEDIKKEEKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVKTT 588
+ ++EE+ E +K+ ++Q++ R R E + + E ++
Sbjct: 333 MWRQEERLWEQ-EKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEE 391
Query: 589 SRSKERSSKSQDRKSESKEKRDILSF--DKIKEQRERERQRQR----EREIRETERRRER 642
R +ER K ++ + +E+ + + + + EQ E+E Q+QR + ++ E E+ +E+
Sbjct: 392 ERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQ 451
Query: 643 EQR--EREQRLEAFHE---------RKEKARLQRERLQLECQRQRLERERM--ERERL-- 687
E++ E+E+++ E R+EK R Q +++ + ++ R + ++M + ER+
Sbjct: 452 EEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWE 511
Query: 688 ERERMRVERERRKEQERIHREREELRRQ------------QEQLRYEQERRPGRRPYDLD 735
+ ER+R + ER +EQ+++ ++ E++R + QE+ E+ER R +
Sbjct: 512 QDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMRE 571
Query: 736 RRDDAYWPEGKRVAMEDRYR 755
+ E K E++ R
Sbjct: 572 EEEMMREQEEKMQEQEEKMR 591
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 82.8 bits (203), Expect = 1e-15
Identities = 69/325 (21%), Positives = 165/325 (50%), Gaps = 26/325 (8%)
Query: 481 EKAKNEPAGKKLSDRKECEVKKEKLSSVDR---HHSVEIKIEKTVIKKEEKI---EKKEE 534
E+ + E ++L ++KE ++EK+ + +I+ ++ + +E+K+ EK E
Sbjct: 482 EQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMRE 541
Query: 535 KKPEDIKKEEKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVKTTSRSKER 594
++ + ++EEK +D+ + R+ K +T +K + ++ R +ER
Sbjct: 542 QEDQMWEQEEKMRDQEQKMWDQEERMEK-------KTQEQEKKTWDQEEKMREEERMRER 594
Query: 595 SSKSQDRKSESKEKRDILSFDKIKEQRERERQRQREREIRETERR---REREQREREQRL 651
K ++ + +E+ + + + K Q + E+ ++E +++E E + +E + E+E+++
Sbjct: 595 EKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKM 654
Query: 652 ---EAFHERKEKA----RLQRERLQLECQRQRLERERMERERLERERMRVERERRKEQER 704
+ E+KEK ++Q + E + + E+E+ME++ E+E+ ++E+ +E+E
Sbjct: 655 WEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEES 714
Query: 705 IHREREELRRQQEQLRYEQERRPGRRPYDLDRRDDAYW-PEGKRVAMEDRYRADFPRPDH 763
+ RERE+ R++E++ EQE + + + +++ W E K E++ P+
Sbjct: 715 M-REREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQ 773
Query: 764 RFHDFDHRDRGQYQDHAIDRREGSR 788
+ ++H ++ Q Q+ ++ E R
Sbjct: 774 KEKLWEH-EKMQEQEKIWEQEEKMR 797
Score = 81.3 bits (199), Expect = 4e-15
Identities = 61/234 (26%), Positives = 122/234 (52%), Gaps = 19/234 (8%)
Query: 524 KKEEKIEK-KEEKKPEDIKKEEKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPV 582
K E++EK +EEKK ++ +K+ +DQ+E K R R + R E T+ + + E +
Sbjct: 418 KMWEQVEKMREEKKMQEQEKKTRDQEE-KMQEEERIREREKKMREEEETM---REQEEKM 473
Query: 583 ISVKTTSRSKERSSKSQDRKSESKEKRDILSFDKIKEQRER----ERQRQREREIRETER 638
+ +E Q R E KEK + +K++EQ E+ E + + + E+ E+
Sbjct: 474 QKQEENMWEQEEKEWQQQRLPEQKEK--LWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEK 531
Query: 639 RREREQREREQRLEAFHERKEKARLQRERLQLECQRQRLERERMERERLERERMRVERER 698
+ R+++ REQ + E++EK R Q +++ + +R + + E++ ++E E ER
Sbjct: 532 KMWRQEKMREQE-DQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEER 590
Query: 699 RKEQERIHREREELRRQQEQLRYEQERRPGRRPYDLDRRDDAYWPEGKRVAMED 752
+E+E+ RE EE+ R+QE+ EQE + + +++ W + +++ ++
Sbjct: 591 MREREKKMREEEEMMREQEEKMQEQEEK-------MQEQEEKMWEQEEKMQEQE 637
Score = 80.9 bits (198), Expect = 5e-15
Identities = 67/240 (27%), Positives = 125/240 (52%), Gaps = 17/240 (7%)
Query: 519 EKTVIKKEEKIEKKEEKKPEDIKKEEKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSK 578
EK + K+EEK+ ++EE+ E K ++Q+E R R + R E+ + K
Sbjct: 285 EKKIRKQEEKMWRQEERLREQEGKM-REQEEKMWRQEKRLREQEKELREQEKELREQKEL 343
Query: 579 GEPVISVKTTSRS---KERSSKSQDRKSESKEKRDILSFDKIKEQRERERQR--QREREI 633
E ++ +E + Q+ K +E+R +++ K+ RE+E++ Q ER
Sbjct: 344 REQEEQMQEQEEKMWEQEEKMREQEEKMWRQEER---LWEQEKQMREQEQKMRDQEERMW 400
Query: 634 RETERRREREQREREQRLEAFHERKEKARLQRERLQLECQRQRLERERMERERLERERMR 693
+ ER RE+E+R REQ E E+ EK R + +++Q + ++ R + E+M+ E ER+R
Sbjct: 401 EQDERLREKEERMREQ--EKMWEQVEKMR-EEKKMQEQEKKTRDQEEKMQ----EEERIR 453
Query: 694 VERERRKEQERIHREREELRRQQEQLRYEQERRPGRRPYDLDRRDDAYWPEGKRVAMEDR 753
++ +E+E RE+EE ++QE+ +EQE + ++ L + + W + K E++
Sbjct: 454 EREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQ-QRLPEQKEKLWEQEKMQEQEEK 512
Score = 79.7 bits (195), Expect = 1e-14
Identities = 60/261 (22%), Positives = 134/261 (51%), Gaps = 24/261 (9%)
Query: 495 RKECEVKKEKLSSVDRHHSVEIKIEKTVIKKEEKIEKKEEKKPEDIKKEEKDQDELKPGP 554
R+E E+ +E+ + + E+ + ++EEK++++EEK E +K + ++++
Sbjct: 599 REEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKM---- 654
Query: 555 TNRSRVTKSGSRGMERTVVMDKSKGEPVISVKTTSRSKERSSKSQDRKSESKEKRDILSF 614
+ R+ + + E + ++ K + E+ ++ Q++K+ +EK
Sbjct: 655 WEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEK------ 708
Query: 615 DKIKEQRERERQRQREREIRETERR-REREQREREQRLEAFHERKEKARLQRERLQLECQ 673
RE E R+RE+++RE E RE+E++ +EQ E E++E+ Q E++ +
Sbjct: 709 -----MREEESMREREKKMREEEEMMREQEEKMQEQE-EKMQEQEEEMWEQEEKMWEQ-- 760
Query: 674 RQRLERERMERERLERERMRV-ERERRKEQERIHREREELRRQQEQLRYEQERRPGRRPY 732
E + E++RL ++ ++ E E+ +EQE+I + E++R Q+E++R ++E+ G+
Sbjct: 761 ----EEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEK 816
Query: 733 DLDRRDDAYWPEGKRVAMEDR 753
+ + + E K E++
Sbjct: 817 MRGQEEKMWGQEEKMWGQEEK 837
Score = 77.4 bits (189), Expect = 6e-14
Identities = 72/321 (22%), Positives = 151/321 (47%), Gaps = 63/321 (19%)
Query: 476 RMISVEKAKNEPAGKKLSDRKECEVKKEKLSSVD---RHHSVEIKIEKTVIKKEEKIEKK 532
+M E+ E GK ++ ++++L + R E++ +K + ++EE+++++
Sbjct: 294 KMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQ 353
Query: 533 EEKKPEDIKKEEKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVKTTSRSK 592
EEK E +K + ++++ R ER +K E + R +
Sbjct: 354 EEKMWEQEEKMREQEEKMW--------------RQEERLWEQEKQMREQ----EQKMRDQ 395
Query: 593 ERSSKSQDRKSESKEKR---DILSFDKIKEQRERERQRQREREIR-------ETERRRER 642
E QD + KE+R ++++++ RE ++ +++E++ R E ER RER
Sbjct: 396 EERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIRER 455
Query: 643 EQREREQRLEAFHERKEKARLQRERL----QLECQRQRLERER---MERERLERERMRV- 694
E++ RE+ E E++EK + Q E + + E Q+QRL ++ E+E+++ + ++
Sbjct: 456 EKKMREEE-ETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIW 514
Query: 695 --------------------ERERRKEQERIHREREELRRQQEQLRYEQERRPGRRPYDL 734
+E+ +EQE E+EE R QEQ ++QE R ++ +
Sbjct: 515 EQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQ 574
Query: 735 DRRDDAYWPEGKRVAMEDRYR 755
+++ W + +++ E+R R
Sbjct: 575 EKKT---WDQEEKMREEERMR 592
Score = 77.0 bits (188), Expect = 8e-14
Identities = 56/227 (24%), Positives = 114/227 (50%), Gaps = 7/227 (3%)
Query: 531 KKEEKKPEDIKKEEKDQD-ELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVKTTS 589
KK ++ E++ KE EL + K + E+ + + K E ++VK
Sbjct: 193 KKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKELK 252
Query: 590 RSKERSSKSQDRKSESKEKRDILSFDKIKEQRERERQRQREREIRETERRREREQREREQ 649
R ER+ + + + ++ ++ ++E++ ++Q E+ R+ ER RE+E + REQ
Sbjct: 253 RKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQ 312
Query: 650 RLEAFHERKEKARLQRERLQLECQRQRLERERMERERLERERMRVERERRKEQERIHRER 709
+ + + K RL+ + +L Q + L ++ RE + E+M+ + E+ EQE RE+
Sbjct: 313 EEKMWRQEK---RLREQEKELREQEKELREQKELRE--QEEQMQEQEEKMWEQEEKMREQ 367
Query: 710 EELRRQQEQLRYEQERRPGRRPYDLDRRDDAYWPEGKRV-AMEDRYR 755
EE +QE+ +EQE++ + + +++ W + +R+ E+R R
Sbjct: 368 EEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMR 414
Score = 75.9 bits (185), Expect = 2e-13
Identities = 74/282 (26%), Positives = 142/282 (50%), Gaps = 38/282 (13%)
Query: 491 KLSDRKECEVKKEKLSSVDRHHSVEIKIEKTVIKKEEKIEKKEEKKPEDIKKEEKDQDEL 550
K +DR E+ KE+ ++ +++ + I EE ++KK + E + E ++ E+
Sbjct: 193 KKADRYIEELTKER-------DALSLELYRNTITNEE-LKKKNAELQEKLPLAESEKSEI 244
Query: 551 KPGPTNRSRVTKSGSRGMERTV-----VMDKSKGEPVISVKTTSRSKERSSKSQDRKSES 605
+ K R +ER V + E + + R +E+ + Q+ K
Sbjct: 245 QLN-------VKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWR 297
Query: 606 KEKRDILSFDKIKEQ-----RERERQRQREREIRETER--RREREQREREQRL----EAF 654
+E+R K++EQ R+ +R R++E+E+RE E+ R ++E RE+E+++ E
Sbjct: 298 QEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKM 357
Query: 655 HERKEKARLQRERLQLECQRQRL-ERERMERERLERERMRVERERRKEQERIHREREELR 713
E++EK R Q E++ Q +RL E+E+ RE + ++MR + ER EQ+ RE+EE
Sbjct: 358 WEQEEKMREQEEKMWR--QEERLWEQEKQMRE--QEQKMRDQEERMWEQDERLREKEERM 413
Query: 714 RQQEQLRYEQERRPGRRPYDLDRRDDAYWPEGKRVAMEDRYR 755
R+QE++ + E+ R + ++ + +++ E+R R
Sbjct: 414 REQEKMWEQVEKM--REEKKMQEQEKKTRDQEEKMQEEERIR 453
Score = 73.2 bits (178), Expect = 1e-12
Identities = 54/248 (21%), Positives = 137/248 (55%), Gaps = 20/248 (8%)
Query: 490 KKLSDRKECEVKKEKLSSVDRHHSVEIKIEKTVIKKEEKI--EKKEEKKPEDIKKEEKDQ 547
+K+ +++ +KEKL ++ ++ ++ + ++EEKI ++K EKK ++ +K+ DQ
Sbjct: 652 EKMWEQQRLPEQKEKLWEHEK-----MQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQ 706
Query: 548 DELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVKTTSRSKERSSKSQDRKSESKE 607
++++ + R R K M M + + E + + + +E Q+ K +E
Sbjct: 707 EKMREEESMREREKK-----MREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQE 761
Query: 608 KRDILSFDKIKEQRER----ERQRQREREIRETERRREREQREREQRLEAFHERKEKARL 663
++ + ++ EQ+E+ E+ +++E+ + E+ R++E++ R Q E ++EK R
Sbjct: 762 EK-MWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQE-EKMRGQEEKMRG 819
Query: 664 QRERLQLECQRQRLERERM--ERERLERERMRVERERRKEQERIHREREELRRQQEQLRY 721
Q E++ + ++ + E+M + E++ + ++E + + ++E++ + E++R Q+E++R
Sbjct: 820 QEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMRE 879
Query: 722 EQERRPGR 729
++E+ G+
Sbjct: 880 QEEKMRGQ 887
Score = 70.1 bits (170), Expect = 9e-12
Identities = 66/281 (23%), Positives = 133/281 (47%), Gaps = 37/281 (13%)
Query: 472 ELHGRMISVEKAKNEPAGKKLSDRKECEVKKEKLSSVDRHHSVEIKI-EKTVIKKEEKIE 530
E +M E+ E K ++ ++EK+ R + K+ E ++++EK++
Sbjct: 621 EQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQ 680
Query: 531 KKEEKKPEDIKKEEKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVKTTSR 590
++EEK E K E+K Q++ K + R E+ K + E + + +
Sbjct: 681 EQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREK-----KMREEEEMMREQEEK 735
Query: 591 SKERSSKSQDRKSESKEKRDILSFDKIKEQRER--ERQRQREREIRETERRREREQRERE 648
+E+ K Q+++ E E+ + K+ EQ E+ E+QR E++ + E + +EQ +
Sbjct: 736 MQEQEEKMQEQEEEMWEQEE-----KMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIW 790
Query: 649 QRLEAFHERKEKARLQRERLQLECQRQRLERERM-----------------------ERE 685
++ E +++EK R Q E+++ + ++ R + E+M + E
Sbjct: 791 EQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEE 850
Query: 686 RLERERMRVERERRKEQERIHREREELRRQQEQLRYEQERR 726
++E E+M+ + E+ +EQE R +EE R+QE+ QE +
Sbjct: 851 KME-EKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEK 890
Score = 68.6 bits (166), Expect = 3e-11
Identities = 60/239 (25%), Positives = 115/239 (48%), Gaps = 11/239 (4%)
Query: 490 KKLSDRKECEVKKEKLSSVDRHHSVEIKIEKTVIKKEEKIEKKEEKKPEDIKK--EEKDQ 547
++L ++KE + EK+ ++ E KI + +K EK +++EKK D +K EE+
Sbjct: 658 QRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQ--EKMEKKTQEQEKKTWDQEKMREEESM 715
Query: 548 DELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVKTTSRSKERSSKSQDRKSESKE 607
E + + + M+ + + E + + +E Q R E KE
Sbjct: 716 REREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKE 775
Query: 608 KRDILSFDKIKEQRERERQRQREREIRETERRREREQREREQRLEAFHER----KEKARL 663
K + +K++EQ + Q ++ R+ E R +E + R +E+++ E+ +EK
Sbjct: 776 K--LWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWG 833
Query: 664 QRERLQLECQRQRLERERMERERL-ERERMRVERERRKEQERIHREREELRRQQEQLRY 721
Q E++ + ++ + E+ME + + E+MR + E+ + QE RE+EE R QE+ Y
Sbjct: 834 QEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEKIY 892
Score = 67.0 bits (162), Expect = 8e-11
Identities = 51/204 (25%), Positives = 110/204 (53%), Gaps = 21/204 (10%)
Query: 587 TTSRSKERSSKSQDRK--SESKEKRDILSFDKIKEQRERER---QRQREREIRETERRRE 641
T K+++++ Q++ +ES++ L+ ++K + ER + + + ++E R+E
Sbjct: 219 TNEELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQE 278
Query: 642 REQREREQRLEAFHERKEKARLQRERLQLECQRQRLERERMERERLERERMRVERERRKE 701
E RE+E+++ +++EK Q ERL+ + + R + E+M R + +R+R + + +E
Sbjct: 279 EELREQEKKI---RKQEEKMWRQEERLREQEGKMREQEEKMWR---QEKRLREQEKELRE 332
Query: 702 QERIHREREELRRQQEQLR------YEQERRPGRRPYDLDRRDDAYWPEGKRVAMEDRYR 755
QE+ RE++ELR Q+EQ++ +EQE + + + R+++ W + K++ +++
Sbjct: 333 QEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKM 392
Query: 756 AD----FPRPDHRFHDFDHRDRGQ 775
D D R + + R R Q
Sbjct: 393 RDQEERMWEQDERLREKEERMREQ 416
>gi|239747174 PREDICTED: hypothetical protein XP_002343931, partial
[Homo sapiens]
Length = 213
Score = 81.6 bits (200), Expect = 3e-15
Identities = 62/205 (30%), Positives = 106/205 (51%), Gaps = 13/205 (6%)
Query: 527 EKIEKKEEKKPEDIKKEEKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVK 586
E ++++ E++ E ++++D K T + R ER D+ + + +
Sbjct: 15 ETMDRQRERRRET----DRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDR 70
Query: 587 TTSRSKERSSKSQDRKSESKEKRDILSFDKIKEQRERERQRQRERE---IRETERRRERE 643
R +ER + +DR+ E++ +RD + +RERQ+Q+ERE +R+ ER +++E
Sbjct: 71 EGERQRERE-RDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKE 129
Query: 644 Q-REREQRLEAFHERKEKARLQRERLQLECQRQRLERERMERERLERERMR--VERERRK 700
RER+ E ER+ +A +RE + E + + RER + ERER R ERER
Sbjct: 130 MGRERQTDRETDRERERQAERERETGR-ERKTEDRHRERERERKRERERKRETKERERHT 188
Query: 701 EQERIHREREELRRQQEQLRYEQER 725
+ ER R+RE R++ Q E+ER
Sbjct: 189 DMER-ERQRETDRKRDRQRESERER 212
Score = 76.6 bits (187), Expect = 1e-13
Identities = 64/213 (30%), Positives = 102/213 (47%), Gaps = 16/213 (7%)
Query: 529 IEKKEEKKPEDIKKEEKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVKTT 588
+E K E + + E D+ + T+R R S+ +R D+ + +
Sbjct: 1 MESKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDR 60
Query: 589 SRSKERSSKSQ-DRKSESKEKRDILSFDKIKEQRERERQRQREREI---RETERRREREQ 644
R +E+ + + +R+ E + RD QRE ER+R +ERE ET+R R++ Q
Sbjct: 61 DREREKQTDREGERQRERERDRD--------RQRETERERDKERETDRHTETDRERQK-Q 111
Query: 645 REREQRLEAFHERKEKARLQRERLQLECQRQRLERERMERER-LERERMRVERERRKEQE 703
+ERE ER+++ + RER Q + + R + ERER RER +R R +E+E
Sbjct: 112 KEREMERVRDREREKQKEMGRER-QTDRETDRERERQAERERETGRERKTEDRHRERERE 170
Query: 704 RIHREREELRRQQEQLRYEQERRPGRRPYDLDR 736
R RERE R +E+ R+ R +R D R
Sbjct: 171 R-KRERERKRETKERERHTDMERERQRETDRKR 202
Score = 75.9 bits (185), Expect = 2e-13
Identities = 61/207 (29%), Positives = 107/207 (51%), Gaps = 15/207 (7%)
Query: 588 TSRSKERSSKSQDRKSESKEKRDILSFDKIKEQR-ERERQRQREREIRETERRREREQR- 645
T E + ++R+ E+ +RD K +++ ER+RQR RER RE +R RERE++
Sbjct: 10 THTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERN-RERDRDREREKQT 68
Query: 646 ----EREQRLEAFHERKEKARLQRERLQLECQRQRLERERMERERLERERMR-VERERRK 700
ER++ E +R+ + +R++ + + +RER +++ E ER+R ERE++K
Sbjct: 69 DREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQK 128
Query: 701 EQERIHREREELRRQQEQLRYEQERRPGRRPYDLDRRDDAYWPEGKRVAMEDRYRADFPR 760
E R + E R++E+ + E+ER GR +R+ + E +R +R R +
Sbjct: 129 EMGRERQTDRETDRERER-QAERERETGR-----ERKTEDRHRERERERKRERERKRETK 182
Query: 761 PDHRFHDFDHRDRGQYQDHAIDRREGS 787
R D + R+R + D DR+ S
Sbjct: 183 ERERHTDME-RERQRETDRKRDRQRES 208
Score = 69.7 bits (169), Expect = 1e-11
Identities = 58/192 (30%), Positives = 94/192 (48%), Gaps = 19/192 (9%)
Query: 525 KEEKIEKKEEKKPEDIKKE---EKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEP 581
KE K E + ++ +E E+D+D + T+R G R ER D+ +
Sbjct: 35 KESKTEDRHSERDRQRDRERNRERDRDREREKQTDRE-----GERQRERE--RDRDRQRE 87
Query: 582 VISVKTTSRSKERSSKSQDRKSESKEKRDILSFDKIKE-QRERERQRQREREI-RETERR 639
+ R +R +++ + + KE+ D+ +E Q+E R+RQ +RE RE ER+
Sbjct: 88 TERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQ 147
Query: 640 REREQRE-REQRLEAFHERKEKARLQRERLQLECQRQRLERERMERERLERERMRVERER 698
ERE+ RE++ E H +E+ R +RER +R+R +ER +ERER R +
Sbjct: 148 AERERETGRERKTEDRHRERERER-KRER-----ERKRETKERERHTDMERERQRETDRK 201
Query: 699 RKEQERIHRERE 710
R Q RER+
Sbjct: 202 RDRQRESERERD 213
Score = 64.7 bits (156), Expect = 4e-10
Identities = 54/200 (27%), Positives = 94/200 (47%), Gaps = 21/200 (10%)
Query: 509 DRHHSVEIKIEKTVIKKEEKIEKKEEKKPEDIKKEEKDQDELKPGPTNRSRVTKSGSRGM 568
+R + E K E +++ + +++ ++ + ++ EK D + G R R + R
Sbjct: 30 ERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTD--REGERQRER-ERDRDRQR 86
Query: 569 ERTVVMDKSKGEPVISVKTTSRSKERSSKSQDRKSESKEKRDILSFDKIKEQR-ERERQR 627
E DK + + R K++ + + + +EK+ + ++ ++ +RER+R
Sbjct: 87 ETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTDRETDRERER 146
Query: 628 QREREIRETERRREREQREREQRLEAFHERKEKARLQRERLQLECQRQRLERER---MER 684
Q ERE RET R R+ E R RE+ E ER+ K R+ ERER MER
Sbjct: 147 QAERE-RETGRERKTEDRHRERERERKRERERK-------------RETKERERHTDMER 192
Query: 685 ERLERERMRVERERRKEQER 704
ER + +R+R E+ER
Sbjct: 193 ERQRETDRKRDRQRESERER 212
Score = 62.0 bits (149), Expect = 3e-09
Identities = 50/187 (26%), Positives = 97/187 (51%), Gaps = 6/187 (3%)
Query: 481 EKAKNEPAGKKLSDRKECEVKKEKLSSVDRHHSVEIKIEKTVIKKEEKIEKKEEKKPEDI 540
++AK + S+R + +E+ DR E + ++ ++ E+ E+ +++ E
Sbjct: 32 DRAKESKTEDRHSERDR-QRDRERNRERDRDREREKQTDREGERQRER-ERDRDRQRETE 89
Query: 541 KKEEKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVKTTSRSKERSSKSQD 600
++ +K+++ + T+R R K R MER ++ K + + + T R +R + Q
Sbjct: 90 RERDKERETDRHTETDRER-QKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQA 148
Query: 601 RKSESKEKRDILSFDKIKEQRERERQRQREREIRETERRREREQREREQRLEAFHERKEK 660
+ E + R+ + D+ +E RERER+R+RER+ RET+ R ERE++ E +R +
Sbjct: 149 ER-ERETGRERKTEDRHRE-RERERKRERERK-RETKERERHTDMERERQRETDRKRDRQ 205
Query: 661 ARLQRER 667
+RER
Sbjct: 206 RESERER 212
Score = 49.3 bits (116), Expect = 2e-05
Identities = 54/207 (26%), Positives = 91/207 (43%), Gaps = 28/207 (13%)
Query: 623 RERQRQREREIRETERRRERE--------------------QREREQRLEAFHERKEKAR 662
R + E R+ ERRRE + QR+RE+ E +R+ + +
Sbjct: 8 RHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQ 67
Query: 663 LQRE-RLQLECQRQRLERERMERER-LERERMR---VERERRKEQERIHREREELRRQQE 717
RE Q E +R R + ERER ERE R +RER+K++ER ER R +++
Sbjct: 68 TDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKER-EMERVRDREREK 126
Query: 718 QLRYEQERRPGRR-PYDLDRRDDAYWPEGKRVAMEDRYR-ADFPRPDHRFHDFDHRDRGQ 775
Q +ER+ R + +R+ + G+ EDR+R + R R + ++R +
Sbjct: 127 QKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKERER 186
Query: 776 YQDHAIDRREGSRPMMGDHRDGQHYGD 802
+ D +R+ + R+ + D
Sbjct: 187 HTDMERERQRETDRKRDRQRESERERD 213
Score = 38.1 bits (87), Expect = 0.039
Identities = 41/167 (24%), Positives = 65/167 (38%), Gaps = 13/167 (7%)
Query: 648 EQRLEAFHERKEKARLQRER---LQLECQRQRLERERMERERLERERMRVERERRKEQER 704
E + E H E + R+R + + +R R + + E ER+R +R+R + +ER
Sbjct: 2 ESKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDR---QRDRERNRER 58
Query: 705 IH-RERE-----ELRRQQEQLRYEQERRPGRRPYDLDRRDDAYWPEGKRVAMEDRYRADF 758
RERE E RQ+E+ R +R R D +R D + E R + + R
Sbjct: 59 DRDREREKQTDREGERQRERERDRDRQRETERERDKERETDRH-TETDRERQKQKEREME 117
Query: 759 PRPDHRFHDFDHRDRGQYQDHAIDRREGSRPMMGDHRDGQHYGDDRH 805
D R + D DR + + +DRH
Sbjct: 118 RVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRH 164
>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
Length = 523
Score = 80.5 bits (197), Expect = 7e-15
Identities = 70/231 (30%), Positives = 123/231 (53%), Gaps = 16/231 (6%)
Query: 504 KLSSVDRHHSVEI--KIEKTVIK-KEEKIEKKEEKKPEDIKKEEKDQDELKPGPTNRSRV 560
+ S ++ H + + K+ +++ K K + E + P K E+ QDE TN R
Sbjct: 117 RTSKEEKKHEIHLVQKLGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDE-----TNHLR- 170
Query: 561 TKSGSRGMERTVVMDKSKGEPVISVKTTSRSKERSSKSQDRKSESKEKRDIL--SFDKIK 618
+ S G + ++ ++ +++ + R +E+ + ++++ +E+ + L ++++
Sbjct: 171 KELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLREQEERLCEQEERLR 230
Query: 619 EQRERERQRQREREIRETERRREREQREREQRLEAFHERKEKARLQRERLQLECQRQRLE 678
EQ ER R+ Q ER + ER RE E+R EQ E E++E+ R Q ERL Q +RL
Sbjct: 231 EQEERLRE-QEERLCEQEERLREHEERLCEQE-ERLCEQEERLREQEERLHE--QEERL- 285
Query: 679 RERMERERLERERMRVERERRKEQERIHREREELRRQQEQLRYEQERRPGR 729
E+ ER R + ER+ + ER +EQE E+EE R+QE+ EQE+ PG+
Sbjct: 286 CEQEERLREQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEKLPGQ 336
Score = 76.3 bits (186), Expect = 1e-13
Identities = 96/375 (25%), Positives = 175/375 (46%), Gaps = 72/375 (19%)
Query: 405 SGRNLWVSGLSSTTRATDLKNLFSKYG------KVVGAKVVTNARSPGARCYGFVTMSTS 458
S ++ G +S+T DL++ + + + +++ N S + TS
Sbjct: 69 SATGIYGEGRASSTTLEDLESQYQELAVALDSSSAIISQLTENINS---------LVRTS 119
Query: 459 DEATKCISHLHRTELHGRMISVEKAKNE---------PAGKKLSDRKECEVK--KEKLSS 507
E K +H + GR S+ K KN+ PAG ++ + E +++L S
Sbjct: 120 KEEKK--HEIHLVQKLGR--SLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELES 175
Query: 508 VDRHHSVEIKIEKTVI----KKEEKIEKKEEKKPEDIKKEEKDQDELKPGPTNRSRVTKS 563
V R E++ + + ++EE++ ++EE+ E ++ ++Q+E R R +
Sbjct: 176 VGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQ-EERLREQEERLCEQEERLREQEE 234
Query: 564 GSRGMERTVVMDKSKGEPVISVKTTSRSKERSSKSQDRKSESKEKRDILSFDKIKEQRER 623
R E + + + +ER + ++R E +E+ ++EQ ER
Sbjct: 235 RLREQEERLCEQEER---------LREHEERLCEQEERLCEQEER--------LREQEER 277
Query: 624 ERQRQREREIRETERRREREQR--EREQRL----EAFHERKEKARLQRERLQLECQRQRL 677
+ Q ER + ER RE+E+R E+E+RL E E++E+ R Q ERL C++++L
Sbjct: 278 LHE-QEERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQEERL---CEQEKL 333
Query: 678 E-RERMERE---RLERERMRVERERRKEQERIHREREEL------RRQQEQLRYEQERRP 727
+ER+ E LE+ER + E+ER E+ER+ E EEL R+Q E+L ++ +
Sbjct: 334 PGQERLLEEVEKLLEQERRQEEQERLLERERLLEEVEELLEQERLRQQDERLWQQETLQE 393
Query: 728 GRRPYDLDRRDDAYW 742
R +L+R + W
Sbjct: 394 LERLRELERMLELGW 408
Score = 72.0 bits (175), Expect = 2e-12
Identities = 58/173 (33%), Positives = 94/173 (54%), Gaps = 10/173 (5%)
Query: 586 KTTSRSKERSSKSQDRKSESKEKRDILSFDKIKEQRERERQRQREREIRETERR-REREQ 644
+T KE S + ++E E +LS + +R+ ER R++E +RE E R RE+E+
Sbjct: 165 ETNHLRKELESVGRQLQAEV-ENNQMLS---LLNRRQEERLREQEERLREQEERLREQEE 220
Query: 645 REREQRLEAFHERKEKARLQRERLQLECQRQRLERERM--ERERL--ERERMRVERERRK 700
R EQ E E++E+ R Q ERL + +R R ER+ + ERL + ER+R + ER
Sbjct: 221 RLCEQE-ERLREQEERLREQEERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLH 279
Query: 701 EQERIHREREELRRQQEQLRYEQERRPGRRPYDLDRRDDAYWPEGKRVAMEDR 753
EQE E+EE R+QE+ EQE R + L +++ + +R+ +++
Sbjct: 280 EQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEK 332
Score = 50.1 bits (118), Expect = 1e-05
Identities = 42/138 (30%), Positives = 72/138 (52%), Gaps = 5/138 (3%)
Query: 619 EQRERERQRQREREIRETERRREREQREREQRLEAFHERKEKARLQRERLQLECQRQRLE 678
EQ + E R +E+ R+ + E E Q L + R+E+ RL+ + +L Q +RL
Sbjct: 160 EQLQDETNHLR-KELESVGRQLQAEV-ENNQMLSLLNRRQEE-RLREQEERLREQEERL- 215
Query: 679 RERMERERLERERMRVERERRKEQE-RIHREREELRRQQEQLRYEQERRPGRRPYDLDRR 737
RE+ ER + ER+R + ER +EQE R+ + E LR +E+L ++ER + ++
Sbjct: 216 REQEERLCEQEERLREQEERLREQEERLCEQEERLREHEERLCEQEERLCEQEERLREQE 275
Query: 738 DDAYWPEGKRVAMEDRYR 755
+ + E + E+R R
Sbjct: 276 ERLHEQEERLCEQEERLR 293
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 79.3 bits (194), Expect = 2e-14
Identities = 118/577 (20%), Positives = 215/577 (37%), Gaps = 66/577 (11%)
Query: 219 ILGETCKSEPVKEESSELEQPFAQ----DTSSVGPDRKLAEEEDLFDSAHPEEGDLDLAS 274
I G+ E +++ +PFA+ + P K+ +EE + S
Sbjct: 145 ISGQEVVREIENQKTDAASKPFAEVRILSCGELIPKSKVKKEEKKRHKSSSSSSSSSSDS 204
Query: 275 ESTAHAQSSKADSLLAVVKREPAEQPGDGERTDCEPVGLEPAVEQSSAASELAEASSEEL 334
+S++ +QSS S E +++ R + E + S S +E+ +E L
Sbjct: 205 DSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRKHKKEKKKRKKSKKSASSESEAENL 264
Query: 335 AEAPTEAPSPEARDSKEDGRKFDFDACNEVPPAPKESSTSEGADQKMSSFKEEKDIKPII 394
P PE E+PP P+ + F K P
Sbjct: 265 EAQPQSTVRPE-----------------EIPPIPE------------NRFLMRK--SPPK 293
Query: 395 KDEKGRVGSGSGRNLWVSGLSSTTRATDLKNLFSKYGKVVGAKVVTNARSPGARCY--GF 452
DEK R R + +S + + L ++ G+ + + R+P F
Sbjct: 294 ADEKERKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRF 353
Query: 453 VTMSTSDEATKCISHLHRTELHGRMISVEKAKNEPAGKKLSDRKECEVKKEKLSSVDRHH 512
T + + R + ++ K+E K + R VK+ K++ H
Sbjct: 354 RRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERKITD---HR 410
Query: 513 SVEIKIEKTVIKKEEKIEKKEEKKPEDIKKEEKDQDELKPGPTNRSRVTKSGSRGMERTV 572
+V + K+++ + K K DI++ + D+ K R++ +KS S+ E
Sbjct: 411 NVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAK-SKSRSKSKE--- 466
Query: 573 VMDKSKGEPVISVKTTSRSKERSSKSQDRKSESKEKRDILSFDKIKEQ---RERERQRQR 629
KSK + S + K S+S+ R E+ ++++ S K K+Q R +E+ +Q
Sbjct: 467 ---KSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQL 523
Query: 630 EREIRETERRREREQREREQRLEAFHERKEKARLQRERLQLECQRQRLERERMERERLER 689
E + E + + +E+ R Q R + + + + R R+R R
Sbjct: 524 ESKSNEHDHSKSKEKDRRAQ------SRSRECDITKGK---HSYNSRTRERSRSRDRSRR 574
Query: 690 ERMRVERERRKEQERIHREREELRRQQEQLRYEQERRPGRRPYDLDRR-----DDAYWPE 744
R R R + HR RE+ R++ + R + R P R DRR + E
Sbjct: 575 VRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSERE 634
Query: 745 GKRVAMEDRYRADFPRPDHRFHDFDHRDR--GQYQDH 779
+ +D+YR + HR + + R + +DH
Sbjct: 635 ESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDH 671
Score = 66.6 bits (161), Expect = 1e-10
Identities = 62/255 (24%), Positives = 105/255 (41%), Gaps = 24/255 (9%)
Query: 482 KAKNEPAGKKLSDRKECEVKKEKLSSVDRHHSVEIKIE------KTVIKKEEKIEKKEEK 535
K K K S KE KE+ S +R+ ++ + V +KE++ + K +
Sbjct: 451 KVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKD 510
Query: 536 KPEDIKKEEKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVKTTSRSKERS 595
+ KE+ Q E K + S+ + R R+ D +KG+ + +T RS+ R
Sbjct: 511 QERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRD 570
Query: 596 ------SKSQDR-KSESKEKRDILSFDKIKEQRERERQRQREREIRETERRREREQRERE 648
S++ DR +S SKE + + +EQ R R R R RE R R + R R
Sbjct: 571 RSRRVRSRTHDRDRSRSKE------YHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRR 624
Query: 649 QRLEAFHERKEKARLQRERLQLECQRQRLERERMERERLERERMRVERERRKEQERIHRE 708
+R ER+E +++ R + + +E E E+ + R RE
Sbjct: 625 RRDSRSSEREESQSRNKDK-----YRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSRE 679
Query: 709 REELRRQQEQLRYEQ 723
++ R Q + +Q
Sbjct: 680 KKADRDQSPFSKIKQ 694
Score = 48.5 bits (114), Expect = 3e-05
Identities = 43/254 (16%), Positives = 99/254 (38%), Gaps = 24/254 (9%)
Query: 479 SVEKAKNEPAGKKLSDRKECEVKKEKLSSVDRHHSVEIKIEKTVIKKEEKIEKKEEKKPE 538
S K K++ K ++ + K++ + R +I K + + +
Sbjct: 514 SRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSR 573
Query: 539 DIKKEEKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVKTTSRSKERSSKS 598
++ D+D + +R R + RG R+ G + R RSS+
Sbjct: 574 RVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSER 633
Query: 599 QDRKSESKEKRDILSFDKIKEQRERERQRQREREIRETERRREREQREREQRLEAFHERK 658
++ +S +K+K R +E + +E E+E+R + R+ + ++
Sbjct: 634 EESQSRNKDK-----------YRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKKA 682
Query: 659 EKARLQRERLQLECQRQRLERERMERERLERERMRVERERRK----EQERIHREREELRR 714
++ + +++ Q L+ ++ + E+ R VE+E +K E + +H + +
Sbjct: 683 DRDQSPFSKIKQSSQDNELKSSMLKNKEDEKIRSSVEKENQKSKGQENDHVHEKNK---- 738
Query: 715 QQEQLRYEQERRPG 728
+++ E PG
Sbjct: 739 -----KFDHESSPG 747
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.129 0.368
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,116,416
Number of Sequences: 37866
Number of extensions: 2465673
Number of successful extensions: 58803
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1035
Number of HSP's successfully gapped in prelim test: 1459
Number of HSP's that attempted gapping in prelim test: 15418
Number of HSP's gapped (non-prelim): 16274
length of query: 953
length of database: 18,247,518
effective HSP length: 112
effective length of query: 841
effective length of database: 14,006,526
effective search space: 11779488366
effective search space used: 11779488366
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.