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Search of human proteins with 7661922
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7661922 RAB21, member RAS oncogene family [Homo sapiens]
(225 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7661922 RAB21, member RAS oncogene family [Homo sapiens] 457 e-129
gi|41393614 RAB5C, member RAS oncogene family isoform a [Homo sa... 170 1e-42
gi|41393545 RAB5C, member RAS oncogene family isoform b [Homo sa... 170 1e-42
gi|19923262 RAB5A, member RAS oncogene family [Homo sapiens] 161 4e-40
gi|4506371 RAB5B, member RAS oncogene family [Homo sapiens] 158 4e-39
gi|21361418 RAB30, member RAS oncogene family [Homo sapiens] 151 4e-37
gi|4506363 RAB13, member RAS oncogene family [Homo sapiens] 150 1e-36
gi|33589861 RAB31, member RAS oncogene family [Homo sapiens] 149 2e-36
gi|169204777 PREDICTED: similar to RAB13, member RAS oncogene fa... 148 3e-36
gi|169205558 PREDICTED: similar to hCG24991 [Homo sapiens] 148 3e-36
gi|169204174 PREDICTED: similar to hCG24991 [Homo sapiens] 148 3e-36
gi|4758988 RAB1A, member RAS oncogene family isoform 1 [Homo sap... 148 4e-36
gi|16933567 mel transforming oncogene [Homo sapiens] 147 9e-36
gi|50234889 RAB43 protein [Homo sapiens] 144 5e-35
gi|11967981 RAB17, member RAS oncogene family [Homo sapiens] 144 5e-35
gi|10190714 RAS-related protein RAB-22A [Homo sapiens] 144 8e-35
gi|13569962 RAB1B, member RAS oncogene family [Homo sapiens] 142 2e-34
gi|7706563 RAB8B, member RAS oncogene family [Homo sapiens] 141 5e-34
gi|38679888 RAB6A, member RAS oncogene family isoform b [Homo sa... 140 7e-34
gi|19923231 RAB6A, member RAS oncogene family isoform a [Homo sa... 140 7e-34
gi|96975097 RAB6B, member RAS oncogene family [Homo sapiens] 140 9e-34
gi|4506365 RAB2A, member RAS oncogene family [Homo sapiens] 140 1e-33
gi|19923483 GTPase Rab14 [Homo sapiens] 139 1e-33
gi|5803135 RAB35, member RAS oncogene family [Homo sapiens] 139 3e-33
gi|190358517 RAB11B, member RAS oncogene family [Homo sapiens] 135 4e-32
gi|4759000 RAB3D, member RAS oncogene family [Homo sapiens] 135 4e-32
gi|21361884 RAB2B protein isoform 1 [Homo sapiens] 134 6e-32
gi|4758984 Ras-related protein Rab-11A [Homo sapiens] 133 1e-31
gi|106507164 RAB12, member RAS oncogene family [Homo sapiens] 132 2e-31
gi|19923985 RAB3C, member RAS oncogene family [Homo sapiens] 132 2e-31
>gi|7661922 RAB21, member RAS oncogene family [Homo sapiens]
Length = 225
Score = 457 bits (1175), Expect = e-129
Identities = 225/225 (100%), Positives = 225/225 (100%)
Query: 1 MAAAGGGGGGAAAAGRAYSFKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKK 60
MAAAGGGGGGAAAAGRAYSFKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKK
Sbjct: 1 MAAAGGGGGGAAAAGRAYSFKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKK 60
Query: 61 LNIGGKRVNLAIWDTAGQERFHALGPIYYRDSNGAILVYDITDEDSFQKVKNWVKELRKM 120
LNIGGKRVNLAIWDTAGQERFHALGPIYYRDSNGAILVYDITDEDSFQKVKNWVKELRKM
Sbjct: 61 LNIGGKRVNLAIWDTAGQERFHALGPIYYRDSNGAILVYDITDEDSFQKVKNWVKELRKM 120
Query: 121 LGNEICLCIVGNKIDLEKERHVSIQEAESYAESVGAKHYHTSAKQNKGIEELFLDLCKRM 180
LGNEICLCIVGNKIDLEKERHVSIQEAESYAESVGAKHYHTSAKQNKGIEELFLDLCKRM
Sbjct: 121 LGNEICLCIVGNKIDLEKERHVSIQEAESYAESVGAKHYHTSAKQNKGIEELFLDLCKRM 180
Query: 181 IETAQVDERAKGNGSSQPGTARRGVQIIDDEPQAQTSGGGCCSSG 225
IETAQVDERAKGNGSSQPGTARRGVQIIDDEPQAQTSGGGCCSSG
Sbjct: 181 IETAQVDERAKGNGSSQPGTARRGVQIIDDEPQAQTSGGGCCSSG 225
>gi|41393614 RAB5C, member RAS oncogene family isoform a [Homo
sapiens]
Length = 216
Score = 170 bits (430), Expect = 1e-42
Identities = 90/226 (39%), Positives = 135/226 (59%), Gaps = 12/226 (5%)
Query: 1 MAAAGGGG--GGAAAAGRAYSFKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLT 58
MA GG G AA + FK+VLLGE VGK+SLVLR+ + +F++ +T+ A+FLT
Sbjct: 1 MAGRGGAARPNGPAAGNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLT 60
Query: 59 KKLNIGGKRVNLAIWDTAGQERFHALGPIYYRDSNGAILVYDITDEDSFQKVKNWVKELR 118
+ + + V IWDTAGQER+H+L P+YYR + AI+VYDIT+ D+F + KNWVKEL+
Sbjct: 61 QTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNTDTFARAKNWVKELQ 120
Query: 119 KMLGNEICLCIVGNKIDLEKERHVSIQEAESYAESVGAKHYHTSAKQNKGIEELFLDLCK 178
+ I + + GNK DL +R V QEA++YA+ TSAK + E+F+ + K
Sbjct: 121 RQASPNIVIALAGNKADLASKRAVEFQEAQAYADDNSLLFMETSAKTAMNVNEIFMAIAK 180
Query: 179 RMIETAQVDERAKGNGSSQPGTARRGVQIIDDEPQAQTSGGGCCSS 224
++ + N + PG RGV + ++ P +++ CCS+
Sbjct: 181 KL------PKNEPQNATGAPG-RNRGVDLQENNPASRSQ---CCSN 216
>gi|41393545 RAB5C, member RAS oncogene family isoform b [Homo
sapiens]
Length = 216
Score = 170 bits (430), Expect = 1e-42
Identities = 90/226 (39%), Positives = 135/226 (59%), Gaps = 12/226 (5%)
Query: 1 MAAAGGGG--GGAAAAGRAYSFKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLT 58
MA GG G AA + FK+VLLGE VGK+SLVLR+ + +F++ +T+ A+FLT
Sbjct: 1 MAGRGGAARPNGPAAGNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLT 60
Query: 59 KKLNIGGKRVNLAIWDTAGQERFHALGPIYYRDSNGAILVYDITDEDSFQKVKNWVKELR 118
+ + + V IWDTAGQER+H+L P+YYR + AI+VYDIT+ D+F + KNWVKEL+
Sbjct: 61 QTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNTDTFARAKNWVKELQ 120
Query: 119 KMLGNEICLCIVGNKIDLEKERHVSIQEAESYAESVGAKHYHTSAKQNKGIEELFLDLCK 178
+ I + + GNK DL +R V QEA++YA+ TSAK + E+F+ + K
Sbjct: 121 RQASPNIVIALAGNKADLASKRAVEFQEAQAYADDNSLLFMETSAKTAMNVNEIFMAIAK 180
Query: 179 RMIETAQVDERAKGNGSSQPGTARRGVQIIDDEPQAQTSGGGCCSS 224
++ + N + PG RGV + ++ P +++ CCS+
Sbjct: 181 KL------PKNEPQNATGAPG-RNRGVDLQENNPASRSQ---CCSN 216
>gi|19923262 RAB5A, member RAS oncogene family [Homo sapiens]
Length = 215
Score = 161 bits (408), Expect = 4e-40
Identities = 84/215 (39%), Positives = 125/215 (58%), Gaps = 10/215 (4%)
Query: 10 GAAAAGRAYSFKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLNIGGKRVN 69
G + FK+VLLGE VGK+SLVLR+ + +F++ +T+ A+FLT+ + + V
Sbjct: 11 GPNTGNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEFQESTIGAAFLTQTVCLDDTTVK 70
Query: 70 LAIWDTAGQERFHALGPIYYRDSNGAILVYDITDEDSFQKVKNWVKELRKMLGNEICLCI 129
IWDTAGQER+H+L P+YYR + AI+VYDIT+E+SF + KNWVKEL++ I + +
Sbjct: 71 FEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNEESFARAKNWVKELQRQASPNIVIAL 130
Query: 130 VGNKIDLEKERHVSIQEAESYAESVGAKHYHTSAKQNKGIEELFLDLCKRMIETAQVDER 189
GNK DL +R V QEA+SYA+ TSAK + + E+F+ + K++ +
Sbjct: 131 SGNKADLANKRAVDFQEAQSYADDNSLLFMETSAKTSMNVNEIFMAIAKKLPK------- 183
Query: 190 AKGNGSSQPGTARRGVQIIDDEPQAQTSGGGCCSS 224
N PG + +D Q + CCS+
Sbjct: 184 ---NEPQNPGANSARGRGVDLTEPTQPTRNQCCSN 215
>gi|4506371 RAB5B, member RAS oncogene family [Homo sapiens]
Length = 215
Score = 158 bits (399), Expect = 4e-39
Identities = 83/215 (38%), Positives = 127/215 (59%), Gaps = 10/215 (4%)
Query: 10 GAAAAGRAYSFKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLNIGGKRVN 69
G A + FK+VLLGE VGK+SLVLR+ + +F++ +T+ A+FLT+ + + V
Sbjct: 11 GQPQASKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQSVCLDDTTVK 70
Query: 70 LAIWDTAGQERFHALGPIYYRDSNGAILVYDITDEDSFQKVKNWVKELRKMLGNEICLCI 129
IWDTAGQER+H+L P+YYR + AI+VYDIT++++F + K WVKEL++ I + +
Sbjct: 71 FEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQETFARAKTWVKELQRQASPSIVIAL 130
Query: 130 VGNKIDLEKERHVSIQEAESYAESVGAKHYHTSAKQNKGIEELFLDLCKRMIETAQVDER 189
GNK DL +R V +EA++YA+ TSAK + +LFL + K++
Sbjct: 131 AGNKADLANKRMVEYEEAQAYADDNSLLFMETSAKTAMNVNDLFLAIAKKL--------- 181
Query: 190 AKGNGSSQPGTARRGVQIIDDEPQAQTSGGGCCSS 224
K + G A R + +D Q+Q + CCS+
Sbjct: 182 PKSEPQNLGGAAGRS-RGVDLHEQSQQNKSQCCSN 215
>gi|21361418 RAB30, member RAS oncogene family [Homo sapiens]
Length = 203
Score = 151 bits (382), Expect = 4e-37
Identities = 76/185 (41%), Positives = 112/185 (60%)
Query: 18 YSFKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLNIGGKRVNLAIWDTAG 77
+ FK+VL+G VGKT LV R+ + F T+ F+ K + I G++V L IWDTAG
Sbjct: 8 FLFKIVLIGNAGVGKTCLVRRFTQGLFPPGQGATIGVDFMIKTVEINGEKVKLQIWDTAG 67
Query: 78 QERFHALGPIYYRDSNGAILVYDITDEDSFQKVKNWVKELRKMLGNEICLCIVGNKIDLE 137
QERF ++ YYR +N IL YDIT E+SF+ + W++E+ + N++ +VGNKIDL
Sbjct: 68 QERFRSITQSYYRSANALILTYDITCEESFRCLPEWLREIEQYASNKVITVLVGNKIDLA 127
Query: 138 KERHVSIQEAESYAESVGAKHYHTSAKQNKGIEELFLDLCKRMIETAQVDERAKGNGSSQ 197
+ R VS Q AE ++E+ + TSAK++ +E+LFLDL R+I A+ + S
Sbjct: 128 ERREVSQQRAEEFSEAQDMYYLETSAKESDNVEKLFLDLACRLISEARQNTLVNNVSSPL 187
Query: 198 PGTAR 202
PG +
Sbjct: 188 PGEGK 192
>gi|4506363 RAB13, member RAS oncogene family [Homo sapiens]
Length = 203
Score = 150 bits (378), Expect = 1e-36
Identities = 70/181 (38%), Positives = 115/181 (63%), Gaps = 2/181 (1%)
Query: 20 FKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLNIGGKRVNLAIWDTAGQE 79
FK++L+G+ VGKT L++R+ E+ FN+ +I+T+ F + ++I GK++ L +WDTAGQE
Sbjct: 9 FKLLLIGDSGVGKTCLIIRFAEDNFNNTYISTIGIDFKIRTVDIEGKKIKLQVWDTAGQE 68
Query: 80 RFHALGPIYYRDSNGAILVYDITDEDSFQKVKNWVKELRKMLGNEICLCIVGNKIDLEKE 139
RF + YYR + G ILVYDITDE SF+ ++NW+K +++ + ++GNK D+E +
Sbjct: 69 RFKTITTAYYRGAMGIILVYDITDEKSFENIQNWMKSIKENASAGVERLLLGNKCDMEAK 128
Query: 140 RHVSIQEAESYAESVGAKHYHTSAKQNKGIEELFLDLCKRMIETAQVDERAKGNGSSQPG 199
R V ++A+ A G + + TSAK + ++E F L + ++ + R GNG+ P
Sbjct: 129 RKVQKEQADKLAREHGIRFFETSAKSSMNVDEAFSSLARDIL--LKSGGRRSGNGNKPPS 186
Query: 200 T 200
T
Sbjct: 187 T 187
>gi|33589861 RAB31, member RAS oncogene family [Homo sapiens]
Length = 195
Score = 149 bits (376), Expect = 2e-36
Identities = 79/176 (44%), Positives = 110/176 (62%), Gaps = 3/176 (1%)
Query: 21 KVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLNIGGKRVNLAIWDTAGQER 80
KV LLG+ VGK+S+V R+ ++ F+ T+ ASF+TK + G + IWDTAGQER
Sbjct: 8 KVCLLGDTGVGKSSIVCRFVQDHFDHNISPTIGASFMTKTVPCGNELHKFLIWDTAGQER 67
Query: 81 FHALGPIYYRDSNGAILVYDITDEDSFQKVKNWVKELRKMLGNEICLCIVGNKIDLEKER 140
FH+L P+YYR S A++VYDIT +DSF +K WVKEL++ I + I GNK DL R
Sbjct: 68 FHSLAPMYYRGSAAAVIVYDITKQDSFYTLKKWVKELKEHGPENIVMAIAGNKCDLSDIR 127
Query: 141 HVSIQEAESYAESVGAKHYHTSAKQNKGIEELFLDLCKRMIETAQVDERAKGNGSS 196
V +++A+ YAES+GA TSAK IEELF + +++ +D GN +
Sbjct: 128 EVPLKDAKEYAESIGAIVVETSAKNAINIEELFQGISRQI---PPLDPHENGNNGT 180
>gi|169204777 PREDICTED: similar to RAB13, member RAS oncogene
family [Homo sapiens]
Length = 327
Score = 148 bits (374), Expect = 3e-36
Identities = 72/191 (37%), Positives = 118/191 (61%), Gaps = 4/191 (2%)
Query: 12 AAAGRAYS--FKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLNIGGKRVN 69
+A +AY FK++L+G+ VGKT L++R+ E+ FN+ +I+T+ F + ++I GK++
Sbjct: 123 SAMAKAYDHLFKLLLIGDSGVGKTCLIIRFAEDNFNNTYISTIGIDFKIRTVDIEGKKIK 182
Query: 70 LAIWDTAGQERFHALGPIYYRDSNGAILVYDITDEDSFQKVKNWVKELRKMLGNEICLCI 129
L +WDTAGQERF + YYR + G IL YDITDE SF+ ++NW+K + + + +
Sbjct: 183 LQVWDTAGQERFKTITTAYYRGAMGIILAYDITDEKSFENIQNWMKSIMENASAGVEHLL 242
Query: 130 VGNKIDLEKERHVSIQEAESYAESVGAKHYHTSAKQNKGIEELFLDLCKRMIETAQVDER 189
+GNK D+E +R V ++A+ A G + + TSAK + ++E F L + ++ + R
Sbjct: 243 LGNKCDMEAKRKVQKEQADKLAREHGIRFFETSAKSSMNVDEAFSSLARDIL--LKSGGR 300
Query: 190 AKGNGSSQPGT 200
GNG+ P T
Sbjct: 301 RSGNGNKPPST 311
>gi|169205558 PREDICTED: similar to hCG24991 [Homo sapiens]
Length = 327
Score = 148 bits (374), Expect = 3e-36
Identities = 72/191 (37%), Positives = 118/191 (61%), Gaps = 4/191 (2%)
Query: 12 AAAGRAYS--FKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLNIGGKRVN 69
+A +AY FK++L+G+ VGKT L++R+ E+ FN+ +I+T+ F + ++I GK++
Sbjct: 123 SAMAKAYDHLFKLLLIGDSGVGKTCLIIRFAEDNFNNTYISTIGIDFKIRTVDIEGKKIK 182
Query: 70 LAIWDTAGQERFHALGPIYYRDSNGAILVYDITDEDSFQKVKNWVKELRKMLGNEICLCI 129
L +WDTAGQERF + YYR + G IL YDITDE SF+ ++NW+K + + + +
Sbjct: 183 LQVWDTAGQERFKTITTAYYRGAMGIILAYDITDEKSFENIQNWMKSIMENASAGVEHLL 242
Query: 130 VGNKIDLEKERHVSIQEAESYAESVGAKHYHTSAKQNKGIEELFLDLCKRMIETAQVDER 189
+GNK D+E +R V ++A+ A G + + TSAK + ++E F L + ++ + R
Sbjct: 243 LGNKCDMEAKRKVQKEQADKLAREHGIRFFETSAKSSMNVDEAFSSLARDIL--LKSGGR 300
Query: 190 AKGNGSSQPGT 200
GNG+ P T
Sbjct: 301 RSGNGNKPPST 311
>gi|169204174 PREDICTED: similar to hCG24991 [Homo sapiens]
Length = 327
Score = 148 bits (374), Expect = 3e-36
Identities = 72/191 (37%), Positives = 118/191 (61%), Gaps = 4/191 (2%)
Query: 12 AAAGRAYS--FKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLNIGGKRVN 69
+A +AY FK++L+G+ VGKT L++R+ E+ FN+ +I+T+ F + ++I GK++
Sbjct: 123 SAMAKAYDHLFKLLLIGDSGVGKTCLIIRFAEDNFNNTYISTIGIDFKIRTVDIEGKKIK 182
Query: 70 LAIWDTAGQERFHALGPIYYRDSNGAILVYDITDEDSFQKVKNWVKELRKMLGNEICLCI 129
L +WDTAGQERF + YYR + G IL YDITDE SF+ ++NW+K + + + +
Sbjct: 183 LQVWDTAGQERFKTITTAYYRGAMGIILAYDITDEKSFENIQNWMKSIMENASAGVEHLL 242
Query: 130 VGNKIDLEKERHVSIQEAESYAESVGAKHYHTSAKQNKGIEELFLDLCKRMIETAQVDER 189
+GNK D+E +R V ++A+ A G + + TSAK + ++E F L + ++ + R
Sbjct: 243 LGNKCDMEAKRKVQKEQADKLAREHGIRFFETSAKSSMNVDEAFSSLARDIL--LKSGGR 300
Query: 190 AKGNGSSQPGT 200
GNG+ P T
Sbjct: 301 RSGNGNKPPST 311
>gi|4758988 RAB1A, member RAS oncogene family isoform 1 [Homo
sapiens]
Length = 205
Score = 148 bits (373), Expect = 4e-36
Identities = 73/205 (35%), Positives = 122/205 (59%), Gaps = 9/205 (4%)
Query: 18 YSFKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLNIGGKRVNLAIWDTAG 77
Y FK++L+G+ VGK+ L+LR+ ++ + + +I+T+ F + + + GK + L IWDTAG
Sbjct: 10 YLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAG 69
Query: 78 QERFHALGPIYYRDSNGAILVYDITDEDSFQKVKNWVKELRKMLGNEICLCIVGNKIDLE 137
QERF + YYR ++G I+VYD+TD++SF VK W++E+ + + +VGNK DL
Sbjct: 70 QERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNKCDLT 129
Query: 138 KERHVSIQEAESYAESVGAKHYHTSAKQNKGIEELFLDLCKRMIETAQVDERAKGNGSSQ 197
++ V A+ +A+S+G TSAK +E+ F+ + A++ +R G G++
Sbjct: 130 TKKVVDYTTAKEFADSLGIPFLETSAKNATNVEQSFMTM------AAEIKKR-MGPGATA 182
Query: 198 PGTARRGVQIIDDEPQAQTSGGGCC 222
G + V+I + SGGGCC
Sbjct: 183 GGAEKSNVKI--QSTPVKQSGGGCC 205
>gi|16933567 mel transforming oncogene [Homo sapiens]
Length = 207
Score = 147 bits (370), Expect = 9e-36
Identities = 74/194 (38%), Positives = 116/194 (59%), Gaps = 5/194 (2%)
Query: 18 YSFKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLNIGGKRVNLAIWDTAG 77
Y FK++L+G+ VGKT ++ R+ E+ FN I+T+ F + + + GKR+ L IWDTAG
Sbjct: 7 YLFKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKRIKLQIWDTAG 66
Query: 78 QERFHALGPIYYRDSNGAILVYDITDEDSFQKVKNWVKELRKMLGNEICLCIVGNKIDLE 137
QERF + YYR + G +LVYDIT+E SF ++NW++ + + ++ I+GNK D+
Sbjct: 67 QERFRTITTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIEEHASADVEKMILGNKCDVN 126
Query: 138 KERHVSIQEAESYAESVGAKHYHTSAKQNKGIEELFLDLCKRMIETAQVDERAKGNGSSQ 197
+R VS + E A G K TSAK N +E F L + + A++D++ +GN
Sbjct: 127 DKRQVSKERGEKLALDYGIKFMETSAKANINVENAFFTLARDI--KAKMDKKLEGN---S 181
Query: 198 PGTARRGVQIIDDE 211
P + +GV+I D+
Sbjct: 182 PQGSNQGVKITPDQ 195
>gi|50234889 RAB43 protein [Homo sapiens]
Length = 212
Score = 144 bits (364), Expect = 5e-35
Identities = 80/185 (43%), Positives = 108/185 (58%), Gaps = 11/185 (5%)
Query: 3 AAGGGGGGAAAAGRAYSFKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLN 62
A G G G + FK+VL+G+ VGKT +V R+ F+++ +T+ F K L
Sbjct: 2 AGPGPGPGDPDEQYDFLFKLVLVGDASVGKTCVVQRFKTGAFSERQGSTIGVDFTMKTLE 61
Query: 63 IGGKRVNLAIWDTAGQERFHALGPIYYRDSNGAILVYDITDEDSFQKVKNWVKELRKMLG 122
I GKRV L IWDTAGQERF + YYR +NGAIL YDIT SF V +W++++RK G
Sbjct: 62 IQGKRVKLQIWDTAGQERFRTITQSYYRSANGAILAYDITKRSSFLSVPHWIEDVRKYAG 121
Query: 123 NEICLCIVGNKIDLEKERHVSIQEAESYAESVGAKHY------HTSAKQNKGIEELFLDL 176
+ I ++GNK DL + R VS+ EA+S AE HY TSAK + +EE FL +
Sbjct: 122 SNIVQLLIGNKSDLSELREVSLAEAQSLAE-----HYDILCAIETSAKDSSNVEEAFLRV 176
Query: 177 CKRMI 181
+I
Sbjct: 177 ATELI 181
>gi|11967981 RAB17, member RAS oncogene family [Homo sapiens]
Length = 212
Score = 144 bits (364), Expect = 5e-35
Identities = 74/180 (41%), Positives = 116/180 (64%), Gaps = 2/180 (1%)
Query: 12 AAAGRAYSFKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLNIGGKRVNLA 71
AA + FK+VLLG G VGK+SL LRY +N F + T+ +F TK +++G + L
Sbjct: 12 AAPSQPRVFKLVLLGSGSVGKSSLALRYVKNDFKSI-LPTVGCAFFTKVVDVGATSLKLE 70
Query: 72 IWDTAGQERFHALGPIYYRDSNGAILVYDITDEDSFQKVKNWVKELRKML-GNEICLCIV 130
IWDTAGQE++H++ +Y+R +N A+LVYDIT +DSF K + W+K+L + L E+ + +V
Sbjct: 71 IWDTAGQEKYHSVCHLYFRGANAALLVYDITRKDSFLKAQQWLKDLEEELHPGEVLVMLV 130
Query: 131 GNKIDLEKERHVSIQEAESYAESVGAKHYHTSAKQNKGIEELFLDLCKRMIETAQVDERA 190
GNK DL +ER V+ QE + +A+S TSAK N + E+F + + +++ + + +A
Sbjct: 131 GNKTDLSQEREVTFQEGKEFADSQKLLFMETSAKLNHQVSEVFNTVAQELLQRSDEEGQA 190
>gi|10190714 RAS-related protein RAB-22A [Homo sapiens]
Length = 194
Score = 144 bits (362), Expect = 8e-35
Identities = 80/173 (46%), Positives = 108/173 (62%), Gaps = 1/173 (0%)
Query: 21 KVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLNIGGKRVNLAIWDTAGQER 80
KV LLG+ VGK+S+V R+ E+ F+ T+ ASF+TK + + IWDTAGQER
Sbjct: 7 KVCLLGDTGVGKSSIVWRFVEDSFDPNINPTIGASFMTKTVQYQNELHKFLIWDTAGQER 66
Query: 81 FHALGPIYYRDSNGAILVYDITDEDSFQKVKNWVKELRKMLGNEICLCIVGNKIDLEKER 140
F AL P+YYR S AI+VYDIT E++F +KNWVKELR+ I + I GNK DL R
Sbjct: 67 FRALAPMYYRGSAAAIIVYDITKEETFSTLKNWVKELRQHGPPNIVVAIAGNKCDLIDVR 126
Query: 141 HVSIQEAESYAESVGAKHYHTSAKQNKGIEELFLDLCKRMIET-AQVDERAKG 192
V ++A+ YA+S+ A TSAK I ELF+++ +R+ T A + KG
Sbjct: 127 EVMERDAKDYADSIHAIFVETSAKNAININELFIEISRRIPSTDANLPSGGKG 179
>gi|13569962 RAB1B, member RAS oncogene family [Homo sapiens]
Length = 201
Score = 142 bits (358), Expect = 2e-34
Identities = 71/205 (34%), Positives = 121/205 (59%), Gaps = 10/205 (4%)
Query: 18 YSFKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLNIGGKRVNLAIWDTAG 77
Y FK++L+G+ VGK+ L+LR+ ++ + + +I+T+ F + + + GK + L IWDTAG
Sbjct: 7 YLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAG 66
Query: 78 QERFHALGPIYYRDSNGAILVYDITDEDSFQKVKNWVKELRKMLGNEICLCIVGNKIDLE 137
QERF + YYR ++G I+VYD+TD++S+ VK W++E+ + + +VGNK DL
Sbjct: 67 QERFRTITSSYYRGAHGIIVVYDVTDQESYANVKQWLQEIDRYASENVNKLLVGNKSDLT 126
Query: 138 KERHVSIQEAESYAESVGAKHYHTSAKQNKGIEELFLDLCKRMIETAQVDERAKGNGSSQ 197
++ V A+ +A+S+G TSAK +E+ F+ + A++ +R +S
Sbjct: 127 TKKVVDNTTAKEFADSLGIPFLETSAKNATNVEQAFMTM------AAEIKKRMGPGAAS- 179
Query: 198 PGTARRGVQIIDDEPQAQTSGGGCC 222
G R ++I D + +GGGCC
Sbjct: 180 -GGERPNLKI--DSTPVKPAGGGCC 201
>gi|7706563 RAB8B, member RAS oncogene family [Homo sapiens]
Length = 207
Score = 141 bits (355), Expect = 5e-34
Identities = 66/161 (40%), Positives = 99/161 (61%)
Query: 18 YSFKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLNIGGKRVNLAIWDTAG 77
Y FK++L+G+ VGKT L+ R+ E+ FN I+T+ F + + + GK++ L IWDTAG
Sbjct: 7 YLFKLLLIGDSGVGKTCLLFRFSEDAFNTTFISTIGIDFKIRTIELDGKKIKLQIWDTAG 66
Query: 78 QERFHALGPIYYRDSNGAILVYDITDEDSFQKVKNWVKELRKMLGNEICLCIVGNKIDLE 137
QERF + YYR + G +LVYDIT+E SF +KNW++ + + +++ I+GNK D+
Sbjct: 67 QERFRTITTAYYRGAMGIMLVYDITNEKSFDNIKNWIRNIEEHASSDVERMILGNKCDMN 126
Query: 138 KERHVSIQEAESYAESVGAKHYHTSAKQNKGIEELFLDLCK 178
+R VS + E A G K TSAK + +EE F L +
Sbjct: 127 DKRQVSKERGEKLAIDYGIKFLETSAKSSANVEEAFFTLAR 167
>gi|38679888 RAB6A, member RAS oncogene family isoform b [Homo
sapiens]
Length = 208
Score = 140 bits (354), Expect = 7e-34
Identities = 78/203 (38%), Positives = 118/203 (58%), Gaps = 11/203 (5%)
Query: 20 FKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLNIGGKRVNLAIWDTAGQE 79
FK+V LGE VGKTSL+ R+ + F++ + T+ FL+K + + + V L +WDTAGQE
Sbjct: 14 FKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAGQE 73
Query: 80 RFHALGPIYYRDSNGAILVYDITDEDSFQKVKNWVKELRKMLGNEICLCIVGNKIDLEKE 139
RF +L P Y RDS A++VYDIT+ +SFQ+ W+ ++R G+++ + +VGNK DL +
Sbjct: 74 RFRSLIPSYIRDSTVAVVVYDITNVNSFQQTTKWIDDVRTERGSDVIIMLVGNKTDLADK 133
Query: 140 RHVSIQEAESYAESVGAKHYHTSAKQNKGIEELFLDLCKRMIETAQVDERAKGNGSSQPG 199
R VSI+E E A+ + TSAK +++LF +V G S+Q
Sbjct: 134 RQVSIEEGERKAKELNVMFIETSAKAGYNVKQLF----------RRVAAALPGMESTQDR 183
Query: 200 TARRGVQIIDDEPQAQ-TSGGGC 221
+ + I ++PQ Q S GGC
Sbjct: 184 SREDMIDIKLEKPQEQPVSEGGC 206
>gi|19923231 RAB6A, member RAS oncogene family isoform a [Homo
sapiens]
Length = 208
Score = 140 bits (354), Expect = 7e-34
Identities = 77/203 (37%), Positives = 118/203 (58%), Gaps = 11/203 (5%)
Query: 20 FKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLNIGGKRVNLAIWDTAGQE 79
FK+V LGE VGKTSL+ R+ + F++ + T+ FL+K + + + + L +WDTAGQE
Sbjct: 14 FKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTIRLQLWDTAGQE 73
Query: 80 RFHALGPIYYRDSNGAILVYDITDEDSFQKVKNWVKELRKMLGNEICLCIVGNKIDLEKE 139
RF +L P Y RDS A++VYDIT+ +SFQ+ W+ ++R G+++ + +VGNK DL +
Sbjct: 74 RFRSLIPSYIRDSAAAVVVYDITNVNSFQQTTKWIDDVRTERGSDVIIMLVGNKTDLADK 133
Query: 140 RHVSIQEAESYAESVGAKHYHTSAKQNKGIEELFLDLCKRMIETAQVDERAKGNGSSQPG 199
R VSI+E E A+ + TSAK +++LF +V G S+Q
Sbjct: 134 RQVSIEEGERKAKELNVMFIETSAKAGYNVKQLF----------RRVAAALPGMESTQDR 183
Query: 200 TARRGVQIIDDEPQAQ-TSGGGC 221
+ + I ++PQ Q S GGC
Sbjct: 184 SREDMIDIKLEKPQEQPVSEGGC 206
>gi|96975097 RAB6B, member RAS oncogene family [Homo sapiens]
Length = 208
Score = 140 bits (353), Expect = 9e-34
Identities = 74/204 (36%), Positives = 117/204 (57%), Gaps = 10/204 (4%)
Query: 20 FKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLNIGGKRVNLAIWDTAGQE 79
FK+V LGE VGKTSL+ R+ + F++ + T+ FL+K + + + V L +WDTAGQE
Sbjct: 14 FKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAGQE 73
Query: 80 RFHALGPIYYRDSNGAILVYDITDEDSFQKVKNWVKELRKMLGNEICLCIVGNKIDLEKE 139
RF +L P Y RDS A++VYDIT+ +SFQ+ W+ ++R G+++ + +VGNK DL +
Sbjct: 74 RFRSLIPSYIRDSTVAVVVYDITNLNSFQQTSKWIDDVRTERGSDVIIMLVGNKTDLADK 133
Query: 140 RHVSIQEAESYAESVGAKHYHTSAKQNKGIEELFLDLCKRMIETAQVDERAKGNGSSQPG 199
R ++I+E E A+ + TSAK +++LF + + V E++K
Sbjct: 134 RQITIEEGEQRAKELSVMFIETSAKTGYNVKQLFRRVASALPGMENVQEKSK-------- 185
Query: 200 TARRGVQIIDDEPQAQTSGGGCCS 223
+ I D+PQ + G CS
Sbjct: 186 --EGMIDIKLDKPQEPPASEGGCS 207
>gi|4506365 RAB2A, member RAS oncogene family [Homo sapiens]
Length = 212
Score = 140 bits (352), Expect = 1e-33
Identities = 73/211 (34%), Positives = 113/211 (53%), Gaps = 7/211 (3%)
Query: 17 AYSFKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLNIGGKRVNLAIWDTA 76
AY FK +++G+ VGK+ L+L++ + +F H T+ F + + I GK++ L IWDTA
Sbjct: 4 AYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTA 63
Query: 77 GQERFHALGPIYYRDSNGAILVYDITDEDSFQKVKNWVKELRKMLGNEICLCIVGNKIDL 136
GQE F ++ YYR + GA+LVYDIT D+F + W+++ R+ + + + ++GNK DL
Sbjct: 64 GQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDL 123
Query: 137 EKERHVSIQEAESYAESVGAKHYHTSAKQNKGIEELFLDLCKRMIETAQ-----VDERAK 191
E R V +E E++A G TSAK +EE F++ K + E Q ++ A
Sbjct: 124 ESRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDINNEAN 183
Query: 192 GNGSSQPGTARRGVQIIDDEPQAQTSGGGCC 222
G A Q +GGGCC
Sbjct: 184 GIKIGPQHAATNATHA--GNQGGQQAGGGCC 212
>gi|19923483 GTPase Rab14 [Homo sapiens]
Length = 215
Score = 139 bits (351), Expect = 1e-33
Identities = 72/208 (34%), Positives = 120/208 (57%), Gaps = 4/208 (1%)
Query: 17 AYSFKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLNIGGKRVNLAIWDTA 76
+Y FK +++G+ VGK+ L+ ++ E KF T+ F T+ + + G+++ L IWDTA
Sbjct: 9 SYIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKIKLQIWDTA 68
Query: 77 GQERFHALGPIYYRDSNGAILVYDITDEDSFQKVKNWVKELRKMLGNEICLCIVGNKIDL 136
GQERF A+ YYR + GA++VYDIT ++ + +W+ + R + + ++GNK DL
Sbjct: 69 GQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIILIGNKADL 128
Query: 137 EKERHVSIQEAESYAESVGAKHYHTSAKQNKGIEELFLDLCKRM---IETAQVDERAKGN 193
E +R V+ +EA+ +AE G SAK + +E+ FL+ K++ I+ +D A +
Sbjct: 129 EAQRDVTYEEAKQFAEENGLLFLEASAKTGENVEDAFLEAAKKIYQNIQDGSLDLNAAES 188
Query: 194 GSSQPGTARRGVQIIDDEPQAQTSGGGC 221
G +A +G + + EPQ Q G GC
Sbjct: 189 GVQHKPSAPQGGR-LTSEPQPQREGCGC 215
>gi|5803135 RAB35, member RAS oncogene family [Homo sapiens]
Length = 201
Score = 139 bits (349), Expect = 3e-33
Identities = 68/178 (38%), Positives = 112/178 (62%), Gaps = 2/178 (1%)
Query: 20 FKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLNIGGKRVNLAIWDTAGQE 79
FK++++G+ VGK+SL+LR+ +N F+ +ITT+ F + + I G++V L IWDTAGQE
Sbjct: 9 FKLLIIGDSGVGKSSLLLRFADNTFSGSYITTIGVDFKIRTVEINGEKVKLQIWDTAGQE 68
Query: 80 RFHALGPIYYRDSNGAILVYDITDEDSFQKVKNWVKELRKMLGNEICLCIVGNKIDLEKE 139
RF + YYR ++G I+VYD+T +SF VK W+ E+ + +++C +VGNK D +
Sbjct: 69 RFRTITSTYYRGTHGVIVVYDVTSAESFVNVKRWLHEINQNC-DDVCRILVGNKNDDPER 127
Query: 140 RHVSIQEAESYAESVGAKHYHTSAKQNKGIEELFLDLCKRMIETAQVDERAKGNGSSQ 197
+ V ++A +A +G + + TSAK+N +EE+F + ++ A+ D AK Q
Sbjct: 128 KVVETEDAYKFAGQMGIQLFETSAKENVNVEEMF-NCITELVLRAKKDNLAKQQQQQQ 184
>gi|190358517 RAB11B, member RAS oncogene family [Homo sapiens]
Length = 218
Score = 135 bits (339), Expect = 4e-32
Identities = 69/176 (39%), Positives = 105/176 (59%), Gaps = 3/176 (1%)
Query: 18 YSFKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLNIGGKRVNLAIWDTAG 77
Y FKVVL+G+ VGK++L+ R+ N+FN + +T+ F T+ + + GK + IWDTAG
Sbjct: 10 YLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAG 69
Query: 78 QERFHALGPIYYRDSNGAILVYDITDEDSFQKVKNWVKELRKMLGNEICLCIVGNKIDLE 137
QER+ A+ YYR + GA+LVYDI +++ V+ W+KELR + I + +VGNK DL
Sbjct: 70 QERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIMLVGNKSDLR 129
Query: 138 KERHVSIQEAESYAESVGAKHYHTSAKQNKGIEELFLDLCK---RMIETAQVDERA 190
R V EA ++AE TSA + +EE F ++ R++ Q+ +RA
Sbjct: 130 HLRAVPTDEARAFAEKNNLSFIETSALDSTNVEEAFKNILTEIYRIVSQKQIADRA 185
>gi|4759000 RAB3D, member RAS oncogene family [Homo sapiens]
Length = 219
Score = 135 bits (339), Expect = 4e-32
Identities = 78/228 (34%), Positives = 124/228 (54%), Gaps = 16/228 (7%)
Query: 1 MAAAGGGGGG---AAAAGRAYSFKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFL 57
MA+AG G AA Y FK++L+G VGKTS + RY ++ F ++T+ F
Sbjct: 1 MASAGDTQAGPRDAADQNFDYMFKLLLIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFK 60
Query: 58 TKKLNIGGKRVNLAIWDTAGQERFHALGPIYYRDSNGAILVYDITDEDSFQKVKNWVKEL 117
K + KR+ L IWDTAGQER+ + YYR + G +L+YDI +++SF V++W ++
Sbjct: 61 VKTVYRHDKRIKLQIWDTAGQERYRTITTAYYRGAMGFLLMYDIANQESFAAVQDWATQI 120
Query: 118 RKMLGNEICLCIVGNKIDLEKERHVSIQEAESYAESVGAKHYHTSAKQNKGIEELFLDL- 176
+ + + +VGNK DLE ER V ++ A+ +G + + SAK+N ++++F L
Sbjct: 121 KTYSWDNAQVILVGNKCDLEDERVVPAEDGRRLADDLGFEFFEASAKENINVKQVFERLV 180
Query: 177 ---CKRMIETAQVDERAKGNGSSQPGTARRGVQIIDDEPQAQTSGGGC 221
C++M E+ E + +GS+ G A + D P Q S C
Sbjct: 181 DVICEKMNESL---EPSSSSGSNGKGPA------VGDAPAPQPSSCSC 219
>gi|21361884 RAB2B protein isoform 1 [Homo sapiens]
Length = 216
Score = 134 bits (337), Expect = 6e-32
Identities = 73/213 (34%), Positives = 115/213 (53%), Gaps = 7/213 (3%)
Query: 17 AYSFKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLNIGGKRVNLAIWDTA 76
AY FK +++G+ VGK+ L+L++ + +F H T+ F + +NI GK++ L IWDTA
Sbjct: 4 AYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMVNIDGKQIKLQIWDTA 63
Query: 77 GQERFHALGPIYYRDSNGAILVYDITDEDSFQKVKNWVKELRKMLGNEICLCIVGNKIDL 136
GQE F ++ YYR + GA+LVYDIT ++F + +W+++ R+ + + + ++GNK DL
Sbjct: 64 GQESFRSITRSYYRGAAGALLVYDITRRETFNHLTSWLEDARQHSSSNMVIMLIGNKSDL 123
Query: 137 EKERHVSIQEAESYAESVGAKHYHTSAKQNKGIEELFLDLCK---RMIETAQVDERAKGN 193
E R V +E E++A G TSAK +EE F++ K R I+ D + N
Sbjct: 124 ESRRDVKREEGEAFAREHGLIFMETSAKTACNVEEAFINTAKEIYRKIQQGLFDVHNEAN 183
Query: 194 ----GSSQPGTARRGVQIIDDEPQAQTSGGGCC 222
G Q + G + S GCC
Sbjct: 184 GIKIGPQQSISTSVGPSASQRNSRDIGSNSGCC 216
>gi|4758984 Ras-related protein Rab-11A [Homo sapiens]
Length = 216
Score = 133 bits (335), Expect = 1e-31
Identities = 70/181 (38%), Positives = 106/181 (58%), Gaps = 3/181 (1%)
Query: 18 YSFKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLNIGGKRVNLAIWDTAG 77
Y FKVVL+G+ VGK++L+ R+ N+FN + +T+ F T+ + + GK + IWDTAG
Sbjct: 10 YLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAG 69
Query: 78 QERFHALGPIYYRDSNGAILVYDITDEDSFQKVKNWVKELRKMLGNEICLCIVGNKIDLE 137
QER+ A+ YYR + GA+LVYDI +++ V+ W+KELR + I + +VGNK DL
Sbjct: 70 QERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIMLVGNKSDLR 129
Query: 138 KERHVSIQEAESYAESVGAKHYHTSAKQNKGIEELF---LDLCKRMIETAQVDERAKGNG 194
R V EA ++AE G TSA + +E F L R++ Q+ +R + +
Sbjct: 130 HLRAVPTDEARAFAEKNGLSFIETSALDSTNVEAAFQTILTEIYRIVSQKQMSDRRENDM 189
Query: 195 S 195
S
Sbjct: 190 S 190
>gi|106507164 RAB12, member RAS oncogene family [Homo sapiens]
Length = 244
Score = 132 bits (333), Expect = 2e-31
Identities = 70/200 (35%), Positives = 113/200 (56%), Gaps = 18/200 (9%)
Query: 6 GGGGGAAAAGRAYS-----------------FKVVLLGEGCVGKTSLVLRYCENKFNDKH 48
GGGGG A A S +V+++G VGKTSL+ R+ ++ F +
Sbjct: 12 GGGGGLGAGSPALSGGQGRRRKQPPRPADFKLQVIIIGSRGVGKTSLMERFTDDTFCEAC 71
Query: 49 ITTLQASFLTKKLNIGGKRVNLAIWDTAGQERFHALGPIYYRDSNGAILVYDITDEDSFQ 108
+T+ F K + + GK++ L IWDTAGQERF+++ YYR + G ILVYDIT +++F
Sbjct: 72 KSTVGVDFKIKTVELRGKKIRLQIWDTAGQERFNSITSAYYRSAKGIILVYDITKKETFD 131
Query: 109 KVKNWVKELRKMLGNEICLCIVGNKIDLEKERHVSIQEAESYAESV-GAKHYHTSAKQNK 167
+ W+K + K + L +VGNK+D E +R ++ Q+ E +A+ + G + SAK N
Sbjct: 132 DLPKWMKMIDKYASEDAELLLVGNKLDCETDREITRQQGEKFAQQITGMRFCEASAKDNF 191
Query: 168 GIEELFLDLCKRMIETAQVD 187
++E+FL L +++ +D
Sbjct: 192 NVDEIFLKLVDDILKKMPLD 211
>gi|19923985 RAB3C, member RAS oncogene family [Homo sapiens]
Length = 227
Score = 132 bits (332), Expect = 2e-31
Identities = 64/174 (36%), Positives = 103/174 (59%), Gaps = 4/174 (2%)
Query: 18 YSFKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLNIGGKRVNLAIWDTAG 77
Y FK++++G VGKTS + RY ++ F ++T+ F K + KR+ L IWDTAG
Sbjct: 29 YMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFKNEKRIKLQIWDTAG 88
Query: 78 QERFHALGPIYYRDSNGAILVYDITDEDSFQKVKNWVKELRKMLGNEICLCIVGNKIDLE 137
QER+ + YYR + G IL+YDIT+E+SF V++W +++ + + +VGNK D+E
Sbjct: 89 QERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVILVGNKCDME 148
Query: 138 KERHVSIQEAESYAESVGAKHYHTSAKQNKGIEELFLDL----CKRMIETAQVD 187
ER +S + + E +G + + TSAK N +++ F L C +M E+ + D
Sbjct: 149 DERVISTERGQHLGEQLGFEFFETSAKDNINVKQTFERLVDIICDKMSESLETD 202
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.134 0.394
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,568,524
Number of Sequences: 37866
Number of extensions: 365637
Number of successful extensions: 2785
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 213
Number of HSP's successfully gapped in prelim test: 36
Number of HSP's that attempted gapping in prelim test: 2363
Number of HSP's gapped (non-prelim): 269
length of query: 225
length of database: 18,247,518
effective HSP length: 99
effective length of query: 126
effective length of database: 14,498,784
effective search space: 1826846784
effective search space used: 1826846784
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.