Search of human proteins with 7661920

Search of human proteins with 7661920

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7661920 eukaryotic translation initiation factor 4A, isoform
3 [Homo sapiens]
         (411 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7661920 eukaryotic translation initiation factor 4A, isoform ...   810   0.0  
gi|83700235 eukaryotic translation initiation factor 4A2 [Homo s...   545   e-155
gi|4503529 eukaryotic translation initiation factor 4A isoform 1...   540   e-154
gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo sapi...   276   2e-74
gi|164419732 DEAD (Asp-Glu-Ala-Asp) box polypeptide 25 [Homo sap...   265   7e-71
gi|8922886 DDX19-like protein [Homo sapiens]                          255   4e-68
gi|4758112 HLA-B associated transcript 1 [Homo sapiens]               254   8e-68
gi|18375623 HLA-B associated transcript 1 [Homo sapiens]              254   8e-68
gi|6005743 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 1 [H...   253   2e-67
gi|21040371 DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 [Homo sapi...   246   4e-65
gi|62241022 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 3 [...   237   1e-62
gi|14251212 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 [Homo sapi...   229   3e-60
gi|62241024 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 2 [...   228   8e-60
gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1 ...   222   4e-58
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi...   214   1e-55
gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo...   210   2e-54
gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked ...   209   5e-54
gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked [...   209   5e-54
gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo sap...   208   6e-54
gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo sap...   208   6e-54
gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2 ...   206   4e-53
gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1...   206   4e-53
gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo sap...   205   7e-53
gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens]         201   1e-51
gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens]          201   1e-51
gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens]    196   4e-50
gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo sapi...   194   1e-49
gi|21071032 DEAD-box protein abstrakt [Homo sapiens]                  192   5e-49
gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3 ...   191   1e-48
gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1 [...   191   1e-48

>gi|7661920 eukaryotic translation initiation factor 4A, isoform 3
           [Homo sapiens]
          Length = 411

 Score =  810 bits (2092), Expect = 0.0
 Identities = 411/411 (100%), Positives = 411/411 (100%)

Query: 1   MATTATMATSGSARKRLLKEEDMTKVEFETSEEVDVTPTFDTMGLREDLLRGIYAYGFEK 60
           MATTATMATSGSARKRLLKEEDMTKVEFETSEEVDVTPTFDTMGLREDLLRGIYAYGFEK
Sbjct: 1   MATTATMATSGSARKRLLKEEDMTKVEFETSEEVDVTPTFDTMGLREDLLRGIYAYGFEK 60

Query: 61  PSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAV 120
           PSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAV
Sbjct: 61  PSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAV 120

Query: 121 QIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRA 180
           QIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRA
Sbjct: 121 QIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRA 180

Query: 181 IKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRIL 240
           IKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRIL
Sbjct: 181 IKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRIL 240

Query: 241 VKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREA 300
           VKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREA
Sbjct: 241 VKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREA 300

Query: 301 NFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNREL 360
           NFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNREL
Sbjct: 301 NFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNREL 360

Query: 361 YIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNVADLI 411
           YIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNVADLI
Sbjct: 361 YIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNVADLI 411


>gi|83700235 eukaryotic translation initiation factor 4A2 [Homo
           sapiens]
          Length = 407

 Score =  545 bits (1404), Expect = e-155
 Identities = 270/378 (71%), Positives = 322/378 (85%), Gaps = 1/378 (0%)

Query: 35  DVTPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSI 94
           ++   FD M L+E LLRGIYAYGFEKPSAIQQRAI   IKG DVIAQ+QSGTGKTATF+I
Sbjct: 30  EIVDNFDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAI 89

Query: 95  SVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLD 154
           S+LQ L+I+ +ETQAL+LAPTRELA QIQK +LALGDYM   CHACIGGTNV  +++KL 
Sbjct: 90  SILQQLEIEFKETQALVLAPTRELAQQIQKVILALGDYMGATCHACIGGTNVRNEMQKLQ 149

Query: 155 Y-GQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQ 213
               H+V GTPGRVFDM+ RR L  + IKM VLDEADEML++GFK+QIY++++ L  + Q
Sbjct: 150 AEAPHIVVGTPGRVFDMLNRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIFQKLNTSIQ 209

Query: 214 VVLISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYD 273
           VVL+SAT+P ++LE+T KFM DPIRILVK++ELTLEGIKQF++ VEREEWK DTLCDLY+
Sbjct: 210 VVLLSATMPTDVLEVTKKFMRDPIRILVKKEELTLEGIKQFYINVEREEWKLDTLCDLYE 269

Query: 274 TLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLIS 333
           TLTITQAVIF NT+RKVDWLTEKM   +FTVS++HGDM QKER+ IM+EFRSG+SRVLI+
Sbjct: 270 TLTITQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRVLIT 329

Query: 334 TDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIE 393
           TD+ ARG+DV QVSL+INYDLP NRE YIHRIGR GR+GRKGVAINFV  +D RILRDIE
Sbjct: 330 TDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFVTEEDKRILRDIE 389

Query: 394 QYYSTQIDEMPMNVADLI 411
            +Y+T ++EMPMNVADLI
Sbjct: 390 TFYNTTVEEMPMNVADLI 407


>gi|4503529 eukaryotic translation initiation factor 4A isoform 1
           [Homo sapiens]
          Length = 406

 Score =  540 bits (1391), Expect = e-154
 Identities = 271/406 (66%), Positives = 328/406 (80%), Gaps = 1/406 (0%)

Query: 7   MATSGSARKRLLKEEDMTKVEFETSEEVDVTPTFDTMGLREDLLRGIYAYGFEKPSAIQQ 66
           M+ S  +R R    + M       S   ++  +FD M L E LLRGIYAYGFEKPSAIQQ
Sbjct: 1   MSASQDSRSRDNGPDGMEPEGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQ 60

Query: 67  RAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGL 126
           RAI   IKG DVIAQ+QSGTGKTATF+IS+LQ +++ ++ TQAL+LAPTRELA QIQK +
Sbjct: 61  RAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVV 120

Query: 127 LALGDYMNVQCHACIGGTNVGEDIRKLDY-GQHVVAGTPGRVFDMIRRRSLRTRAIKMLV 185
           +ALGDYM   CHACIGGTNV  +++KL     H++ GTPGRVFDM+ RR L  + IKM V
Sbjct: 121 MALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFV 180

Query: 186 LDEADEMLNKGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRILVKRDE 245
           LDEADEML++GFK+QIYD+++ L   TQVVL+SAT+P ++LE+T KFM DPIRILVK++E
Sbjct: 181 LDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEE 240

Query: 246 LTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVS 305
           LTLEGI+QF++ VEREEWK DTLCDLY+TLTITQAVIF NT+RKVDWLTEKM   +FTVS
Sbjct: 241 LTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVS 300

Query: 306 SMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRI 365
           +MHGDM QKER+ IM+EFRSG+SRVLI+TD+ ARG+DV QVSL+INYDLP NRE YIHRI
Sbjct: 301 AMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRI 360

Query: 366 GRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNVADLI 411
           GR GR+GRKGVAIN V  +D R LRDIE +Y+T I+EMP+NVADLI
Sbjct: 361 GRGGRFGRKGVAINMVTEEDKRTLRDIETFYNTSIEEMPLNVADLI 406


>gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo
           sapiens]
          Length = 483

 Score =  276 bits (707), Expect = 2e-74
 Identities = 143/378 (37%), Positives = 237/378 (62%), Gaps = 7/378 (1%)

Query: 35  DVTPT----FDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTA 90
           DVT T    F+   L+ +LL GI+  G+EKPS IQ+ +I   + GRD++A++++GTGK+ 
Sbjct: 89  DVTSTKGNEFEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSG 148

Query: 91  TFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMN-VQCHACIGGTNVGED 149
            + I +L+ LD++    QA+++ PTRELA+Q+ +  + +  +M   +  A  GGTN+ +D
Sbjct: 149 AYLIPLLERLDLKKDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDD 208

Query: 150 IRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLP 209
           I +LD   HVV  TPGR+ D+I++   +   ++M+VLDEAD++L++ F + + D+   LP
Sbjct: 209 IMRLDDTVHVVIATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQDFVQIMEDIILTLP 268

Query: 210 PATQVVLISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLC 269
              Q++L SAT P  + +  N  +  P  I +  +ELTL+G+ Q++  V  E  K   L 
Sbjct: 269 KNRQILLYSATFPLSVQKFMNSHLQKPYEINLM-EELTLKGVTQYYAYVT-ERQKVHCLN 326

Query: 270 DLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASR 329
            L+  L I Q++IFCN+ ++V+ L +K+ +  ++   +H  M Q+ R  +  +FR+G  R
Sbjct: 327 TLFSRLQINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCR 386

Query: 330 VLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRIL 389
            L+ TD++ RG+D+  V+++IN+D P   E Y+HRIGRSGR+G  G+AIN +  DD   L
Sbjct: 387 NLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLITYDDRFNL 446

Query: 390 RDIEQYYSTQIDEMPMNV 407
           + IE+   T+I  +P N+
Sbjct: 447 KSIEEQLGTEIKPIPSNI 464


>gi|164419732 DEAD (Asp-Glu-Ala-Asp) box polypeptide 25 [Homo
           sapiens]
          Length = 483

 Score =  265 bits (676), Expect = 7e-71
 Identities = 143/376 (38%), Positives = 237/376 (63%), Gaps = 14/376 (3%)

Query: 39  TFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKG--RDVIAQSQSGTGKTATFSISV 96
           TF+ + L+E+LL+GIYA GF +PS IQ+ A+  ++    +++IAQSQSGTGKTA F +++
Sbjct: 98  TFEELRLKEELLKGIYAMGFNRPSKIQEMALPMMLAHPPQNLIAQSQSGTGKTAAFVLAM 157

Query: 97  LQCLDIQVRETQALILAPTRELAVQIQKGLLALGDY-MNVQCHACIGGTNVGEDIRKLDY 155
           L  ++      Q L LAPT ELA+Q  + +  +G + ++VQ    I G  +    R  D 
Sbjct: 158 LSRVNALELFPQCLCLAPTYELALQTGRVVEQMGKFCVDVQVMYAIRGNRIP---RGTDI 214

Query: 156 GQHVVAGTPGRVFDM-IRRRSLRTRAIKMLVLDEADEMLN-KGFKEQIYDVYRYLPPATQ 213
            + ++ GTPG V D   + + +    I++ VLDEAD M++ +GF +    + R LP   Q
Sbjct: 215 TKQIIIGTPGTVLDWCFKLKLIDLTKIRVFVLDEADVMIDTQGFSDHSIRIQRALPSECQ 274

Query: 214 VVLISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYD 273
           ++L SAT    +     + + DP  I ++++ELTL  I+Q++V  E  + K+  LC++Y 
Sbjct: 275 MLLFSATFEDSVWHFAERIIPDPNVIKLRKEELTLNNIRQYYVLCEHRKDKYQALCNIYG 334

Query: 274 TLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLIS 333
           ++TI QA+IFC T+R   WLT +M +    VS + G++  ++R SI++ FR G  +VLI+
Sbjct: 335 SITIGQAIIFCQTRRNAKWLTVEMIQDGHQVSLLSGELTVEQRASIIQRFRDGKEKVLIT 394

Query: 334 TDVWARGLDVPQVSLIINYDLPNNR------ELYIHRIGRSGRYGRKGVAINFVKNDDIR 387
           T+V ARG+DV QV++++N+DLP  +      E Y+HRIGR+GR+G+KG+A N ++ D++ 
Sbjct: 395 TNVCARGIDVKQVTIVVNFDLPVKQGEEPDYETYLHRIGRTGRFGKKGLAFNMIEVDELP 454

Query: 388 ILRDIEQYYSTQIDEM 403
            L  I+ ++++ I ++
Sbjct: 455 SLMKIQDHFNSSIKQL 470


>gi|8922886 DDX19-like protein [Homo sapiens]
          Length = 478

 Score =  255 bits (652), Expect = 4e-68
 Identities = 145/389 (37%), Positives = 239/389 (61%), Gaps = 23/389 (5%)

Query: 39  TFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKG--RDVIAQSQSGTGKTATFSISV 96
           +F+ + L+  LL+G+YA GF +PS IQ+ A+  ++    +++IAQSQSGTGKTA F +++
Sbjct: 92  SFEELRLKPQLLQGVYAMGFNRPSKIQENALPMMLAEPPQNLIAQSQSGTGKTAAFVLAM 151

Query: 97  LQCLDIQVRETQALILAPTRELAVQIQKGLLALGD-YMNVQCHACIGGTNVGEDIRKLDY 155
           L  ++   R  Q L L+PT ELA+Q  K +  +G  Y  ++    + G        KL+ 
Sbjct: 152 LSRVEPSDRYPQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRGN-------KLER 204

Query: 156 GQ----HVVAGTPGRVFDMIRR-RSLRTRAIKMLVLDEADEML-NKGFKEQIYDVYRYLP 209
           GQ     +V GTPG V D   + + +  + IK+ VLDEAD M+  +G ++Q   + R LP
Sbjct: 205 GQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLP 264

Query: 210 PATQVVLISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLC 269
              Q++L SAT    + +   K + DP  I +KR+E TL+ IKQ++V     + KF  LC
Sbjct: 265 RNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALC 324

Query: 270 DLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASR 329
           +LY  +TI QA+IFC+T++   WL  ++ +    V+ + G+M  ++R ++++ FR G  +
Sbjct: 325 NLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEK 384

Query: 330 VLISTDVWARGLDVPQVSLIINYDLPNNR------ELYIHRIGRSGRYGRKGVAINFV-K 382
           VL++T+V ARG+DV QVS++IN+DLP ++      E Y+HRIGR+GR+G++G+A+N V  
Sbjct: 385 VLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDS 444

Query: 383 NDDIRILRDIEQYYSTQIDEMPMNVADLI 411
              + IL  I+++++ +I+ +  +  D I
Sbjct: 445 KHSMNILNRIQEHFNKKIERLDTDDLDEI 473


>gi|4758112 HLA-B associated transcript 1 [Homo sapiens]
          Length = 428

 Score =  254 bits (650), Expect = 8e-68
 Identities = 140/365 (38%), Positives = 218/365 (59%), Gaps = 6/365 (1%)

Query: 45  LREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQV 104
           L+ +LLR I   GFE PS +Q   I Q I G DV+ Q++SG GKTA F ++ LQ L+   
Sbjct: 52  LKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQLEPVT 111

Query: 105 RETQALILAPTRELAVQIQKGLLALGDYM-NVQCHACIGGTNVGEDIRKLDYG-QHVVAG 162
            +   L++  TRELA QI K       YM NV+     GG ++ +D   L     H+V G
Sbjct: 112 GQVSVLVMCHTRELAFQISKEYERFSKYMPNVKVAVFFGGLSIKKDEEVLKKNCPHIVVG 171

Query: 163 TPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNK-GFKEQIYDVYRYLPPATQVVLISATL 221
           TPGR+  + R +SL  + IK  +LDE D+ML +   +  + +++R  P   QV++ SATL
Sbjct: 172 TPGRILALARNKSLNLKHIKHFILDECDKMLEQLDMRRDVQEIFRMTPHEKQVMMFSATL 231

Query: 222 PHEILEMTNKFMTDPIRILVKRD-ELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQA 280
             EI  +  KFM DP+ I V  + +LTL G++Q++V ++  E K   L DL D L   Q 
Sbjct: 232 SKEIRPVCRKFMQDPMEIFVDDETKLTLHGLQQYYVKLKDNE-KNRKLFDLLDVLEFNQV 290

Query: 281 VIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARG 340
           VIF  + ++   L + + E NF   ++H  MPQ+ER S  ++F+    R+L++T+++ RG
Sbjct: 291 VIFVKSVQRCIALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATNLFGRG 350

Query: 341 LDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKND-DIRILRDIEQYYSTQ 399
           +D+ +V++  NYD+P + + Y+HR+ R+GR+G KG+AI FV ++ D +IL D++  +   
Sbjct: 351 MDIERVNIAFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQDRFEVN 410

Query: 400 IDEMP 404
           I E+P
Sbjct: 411 ISELP 415


>gi|18375623 HLA-B associated transcript 1 [Homo sapiens]
          Length = 428

 Score =  254 bits (650), Expect = 8e-68
 Identities = 140/365 (38%), Positives = 218/365 (59%), Gaps = 6/365 (1%)

Query: 45  LREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQV 104
           L+ +LLR I   GFE PS +Q   I Q I G DV+ Q++SG GKTA F ++ LQ L+   
Sbjct: 52  LKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQLEPVT 111

Query: 105 RETQALILAPTRELAVQIQKGLLALGDYM-NVQCHACIGGTNVGEDIRKLDYG-QHVVAG 162
            +   L++  TRELA QI K       YM NV+     GG ++ +D   L     H+V G
Sbjct: 112 GQVSVLVMCHTRELAFQISKEYERFSKYMPNVKVAVFFGGLSIKKDEEVLKKNCPHIVVG 171

Query: 163 TPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNK-GFKEQIYDVYRYLPPATQVVLISATL 221
           TPGR+  + R +SL  + IK  +LDE D+ML +   +  + +++R  P   QV++ SATL
Sbjct: 172 TPGRILALARNKSLNLKHIKHFILDECDKMLEQLDMRRDVQEIFRMTPHEKQVMMFSATL 231

Query: 222 PHEILEMTNKFMTDPIRILVKRD-ELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQA 280
             EI  +  KFM DP+ I V  + +LTL G++Q++V ++  E K   L DL D L   Q 
Sbjct: 232 SKEIRPVCRKFMQDPMEIFVDDETKLTLHGLQQYYVKLKDNE-KNRKLFDLLDVLEFNQV 290

Query: 281 VIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARG 340
           VIF  + ++   L + + E NF   ++H  MPQ+ER S  ++F+    R+L++T+++ RG
Sbjct: 291 VIFVKSVQRCIALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATNLFGRG 350

Query: 341 LDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKND-DIRILRDIEQYYSTQ 399
           +D+ +V++  NYD+P + + Y+HR+ R+GR+G KG+AI FV ++ D +IL D++  +   
Sbjct: 351 MDIERVNIAFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQDRFEVN 410

Query: 400 IDEMP 404
           I E+P
Sbjct: 411 ISELP 415


>gi|6005743 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 1 [Homo
           sapiens]
          Length = 479

 Score =  253 bits (646), Expect = 2e-67
 Identities = 144/389 (37%), Positives = 239/389 (61%), Gaps = 23/389 (5%)

Query: 39  TFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKG--RDVIAQSQSGTGKTATFSISV 96
           +F+ + L+  LL+G+YA GF +PS IQ+ A+  ++    +++IAQSQSGTGKTA F +++
Sbjct: 93  SFEELRLKPQLLQGVYAMGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAM 152

Query: 97  LQCLDIQVRETQALILAPTRELAVQIQKGLLALGD-YMNVQCHACIGGTNVGEDIRKLDY 155
           L  ++   +  Q L L+PT ELA+Q  K +  +G  Y  ++    + G        KL+ 
Sbjct: 153 LSQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRGN-------KLER 205

Query: 156 GQ----HVVAGTPGRVFDMIRR-RSLRTRAIKMLVLDEADEML-NKGFKEQIYDVYRYLP 209
           GQ     +V GTPG V D   + + +  + IK+ VLDEAD M+  +G ++Q   + R LP
Sbjct: 206 GQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLP 265

Query: 210 PATQVVLISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLC 269
              Q++L SAT    + +   K + DP  I +KR+E TL+ IKQ++V     + KF  LC
Sbjct: 266 RNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALC 325

Query: 270 DLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASR 329
           +LY  +TI QA+IFC+T++   WL  ++ +    V+ + G+M  ++R ++++ FR G  +
Sbjct: 326 NLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEK 385

Query: 330 VLISTDVWARGLDVPQVSLIINYDLPNNR------ELYIHRIGRSGRYGRKGVAINFV-K 382
           VL++T+V ARG+DV QVS++IN+DLP ++      E Y+HRIGR+GR+G++G+A+N V  
Sbjct: 386 VLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDS 445

Query: 383 NDDIRILRDIEQYYSTQIDEMPMNVADLI 411
              + IL  I+++++ +I+ +  +  D I
Sbjct: 446 KHSMNILNRIQEHFNKKIERLDTDDLDEI 474


>gi|21040371 DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 [Homo
           sapiens]
          Length = 427

 Score =  246 bits (627), Expect = 4e-65
 Identities = 133/368 (36%), Positives = 218/368 (59%), Gaps = 6/368 (1%)

Query: 45  LREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQV 104
           L+ +LLR I   GFE PS +Q   I Q I G DV+ Q++SG GKTA F ++ LQ ++   
Sbjct: 51  LKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQIEPVN 110

Query: 105 RETQALILAPTRELAVQIQKGLLALGDYM-NVQCHACIGGTNVGEDIRKLDYG-QHVVAG 162
            +   L++  TRELA QI K       YM +V+     GG ++ +D   L     HVV G
Sbjct: 111 GQVTVLVMCHTRELAFQISKEYERFSKYMPSVKVSVFFGGLSIKKDEEVLKKNCPHVVVG 170

Query: 163 TPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNK-GFKEQIYDVYRYLPPATQVVLISATL 221
           TPGR+  ++R RS   + +K  VLDE D+ML +   +  + +++R  P   Q ++ SATL
Sbjct: 171 TPGRILALVRNRSFSLKNVKHFVLDECDKMLEQLDMRRDVQEIFRLTPHEKQCMMFSATL 230

Query: 222 PHEILEMTNKFMTDPIRILVKRD-ELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQA 280
             +I  +  KFM DP+ + V  + +LTL G++Q++V ++  E K   L DL D L   Q 
Sbjct: 231 SKDIRPVCRKFMQDPMEVFVDDETKLTLHGLQQYYVKLKDSE-KNRKLFDLLDVLEFNQV 289

Query: 281 VIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARG 340
           +IF  + ++   L + + E NF   ++H  M Q+ER S  ++F+    R+L++T+++ RG
Sbjct: 290 IIFVKSVQRCMALAQLLVEQNFPAIAIHRGMAQEERLSRYQQFKDFQRRILVATNLFGRG 349

Query: 341 LDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKND-DIRILRDIEQYYSTQ 399
           +D+ +V+++ NYD+P + + Y+HR+ R+GR+G KG+AI FV ++ D +IL D++  +   
Sbjct: 350 MDIERVNIVFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQDRFEVN 409

Query: 400 IDEMPMNV 407
           + E+P  +
Sbjct: 410 VAELPEEI 417


>gi|62241022 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 3
           [Homo sapiens]
          Length = 370

 Score =  237 bits (605), Expect = 1e-62
 Identities = 137/371 (36%), Positives = 226/371 (60%), Gaps = 23/371 (6%)

Query: 57  GFEKPSAIQQRAIKQIIKG--RDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAP 114
           GF +PS IQ+ A+  ++    +++IAQSQSGTGKTA F +++L  ++   +  Q L L+P
Sbjct: 2   GFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSP 61

Query: 115 TRELAVQIQKGLLALGD-YMNVQCHACIGGTNVGEDIRKLDYGQ----HVVAGTPGRVFD 169
           T ELA+Q  K +  +G  Y  ++    + G        KL+ GQ     +V GTPG V D
Sbjct: 62  TYELALQTGKVIEQMGKFYPELKLAYAVRGN-------KLERGQKISEQIVIGTPGTVLD 114

Query: 170 MIRR-RSLRTRAIKMLVLDEADEML-NKGFKEQIYDVYRYLPPATQVVLISATLPHEILE 227
              + + +  + IK+ VLDEAD M+  +G ++Q   + R LP   Q++L SAT    + +
Sbjct: 115 WCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWK 174

Query: 228 MTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTK 287
              K + DP  I +KR+E TL+ IKQ++V     + KF  LC+LY  +TI QA+IFC+T+
Sbjct: 175 FAQKVVPDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTR 234

Query: 288 RKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVS 347
           +   WL  ++ +    V+ + G+M  ++R ++++ FR G  +VL++T+V ARG+DV QVS
Sbjct: 235 KTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVS 294

Query: 348 LIINYDLPNNR------ELYIHRIGRSGRYGRKGVAINFV-KNDDIRILRDIEQYYSTQI 400
           ++IN+DLP ++      E Y+HRIGR+GR+G++G+A+N V     + IL  I+++++ +I
Sbjct: 295 VVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKI 354

Query: 401 DEMPMNVADLI 411
           + +  +  D I
Sbjct: 355 ERLDTDDLDEI 365


>gi|14251212 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 [Homo
           sapiens]
          Length = 824

 Score =  229 bits (584), Expect = 3e-60
 Identities = 132/370 (35%), Positives = 212/370 (57%), Gaps = 11/370 (2%)

Query: 21  EDMTKVEFETSEEVDVTPT-FDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVI 79
           +D++     T + +   P  F+++ L   +L G+ A GFE+PS +Q +AI     G D+I
Sbjct: 44  QDLSSPRTRTGDVLLAEPADFESLLLSRPVLEGLRAAGFERPSPVQLKAIPLGRCGLDLI 103

Query: 80  AQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMN-VQCH 138
            Q++SGTGKT  FS   L  L ++   TQ LILAPTRE+AVQI   + A+G  M  ++CH
Sbjct: 104 VQAKSGTGKTCVFSTIALDSLVLENLSTQILILAPTREIAVQIHSVITAIGIKMEGLECH 163

Query: 139 ACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKG-F 197
             IGGT + +D  +L    H+  G+PGR+  +I    L   +I++ +LDEAD++L +G F
Sbjct: 164 VFIGGTPLSQDKTRLKKC-HIAVGSPGRIKQLIELDYLNPGSIRLFILDEADKLLEEGSF 222

Query: 198 KEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVA 257
           +EQI  +Y  LP + Q++ +SAT P  +     K+M DP  + +   + +L G+KQ++  
Sbjct: 223 QEQINWIYSSLPASKQMLAVSATYPEFLANALTKYMRDPTFVRLNSSDPSLIGLKQYYKV 282

Query: 258 VERE-------EWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGD 310
           V          E K   L +L+  +   QA++F N   +   L + +    F    + G+
Sbjct: 283 VNSYPLAHKVFEEKTQHLQELFSRIPFNQALVFSNLHSRAQHLADILSSKGFPAECISGN 342

Query: 311 MPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGR 370
           M Q +R   M + +    RVLISTD+ +RG+D  +V+L++N D+P + E Y+HRIGR+GR
Sbjct: 343 MNQNQRLDAMAKLKHFHCRVLISTDLTSRGIDAEKVNLVVNLDVPLDWETYMHRIGRAGR 402

Query: 371 YGRKGVAINF 380
           +G  G+ + +
Sbjct: 403 FGTLGLTVTY 412


>gi|62241024 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 2
           [Homo sapiens]
          Length = 448

 Score =  228 bits (581), Expect = 8e-60
 Identities = 130/359 (36%), Positives = 219/359 (61%), Gaps = 21/359 (5%)

Query: 67  RAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGL 126
           ++ +++   +++IAQSQSGTGKTA F +++L  ++   +  Q L L+PT ELA+Q  K +
Sbjct: 92  KSFEELRLPQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGKVI 151

Query: 127 LALGD-YMNVQCHACIGGTNVGEDIRKLDYGQ----HVVAGTPGRVFDMIRR-RSLRTRA 180
             +G  Y  ++    + G        KL+ GQ     +V GTPG V D   + + +  + 
Sbjct: 152 EQMGKFYPELKLAYAVRGN-------KLERGQKISEQIVIGTPGTVLDWCSKLKFIDPKK 204

Query: 181 IKMLVLDEADEML-NKGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRI 239
           IK+ VLDEAD M+  +G ++Q   + R LP   Q++L SAT    + +   K + DP  I
Sbjct: 205 IKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVI 264

Query: 240 LVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMRE 299
            +KR+E TL+ IKQ++V     + KF  LC+LY  +TI QA+IFC+T++   WL  ++ +
Sbjct: 265 KLKREEETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSK 324

Query: 300 ANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNR- 358
               V+ + G+M  ++R ++++ FR G  +VL++T+V ARG+DV QVS++IN+DLP ++ 
Sbjct: 325 EGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKD 384

Query: 359 -----ELYIHRIGRSGRYGRKGVAINFV-KNDDIRILRDIEQYYSTQIDEMPMNVADLI 411
                E Y+HRIGR+GR+G++G+A+N V     + IL  I+++++ +I+ +  +  D I
Sbjct: 385 GNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTDDLDEI 443


>gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1
           [Homo sapiens]
          Length = 455

 Score =  222 bits (566), Expect = 4e-58
 Identities = 125/395 (31%), Positives = 212/395 (53%), Gaps = 9/395 (2%)

Query: 19  KEEDMTKVEFETSEEVDVTPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDV 78
           +E D      +   E + T TF  +G+ + L       G+ KP+ IQ  AI   ++GRD+
Sbjct: 5   EEHDSPTEASQPIVEEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDI 64

Query: 79  IAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCH 138
           I  +++G+GKT  F++ +L  L    +   AL+L PTRELA QI +   ALG  + VQ  
Sbjct: 65  IGLAETGSGKTGAFALPILNALLETPQRLFALVLTPTRELAFQISEQFEALGSSIGVQSA 124

Query: 139 ACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRR-RSLRTRAIKMLVLDEADEMLNKGF 197
             +GG +       L    H++  TPGR+ D +   +    RA+K LV+DEAD +LN  F
Sbjct: 125 VIVGGIDSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDF 184

Query: 198 KEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVA 257
           + ++  + + +P   +  L SAT+  ++ ++    + +P++  V     T+E ++Q+++ 
Sbjct: 185 ETEVDKILKVIPRDRKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQYYIF 244

Query: 258 VEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERE 317
           +   ++K   L  + + L     +IFC+T          +R   FT   +HG M Q +R 
Sbjct: 245 IP-SKFKDTYLVYILNELAGNSFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQSKRL 303

Query: 318 SIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVA 377
             + +F++ A  +L++TDV +RGLD+P V +++N+D+P + + YIHR+GR+ R GR G A
Sbjct: 304 GSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKA 363

Query: 378 INFVKNDDIRILRDIEQY-------YSTQIDEMPM 405
           I FV   D+ + + IE         + TQ DE+ M
Sbjct: 364 ITFVTQYDVELFQRIEHLIGKKLPGFPTQDDEVMM 398


>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
           sapiens]
          Length = 1031

 Score =  214 bits (545), Expect = 1e-55
 Identities = 123/358 (34%), Positives = 201/358 (56%), Gaps = 10/358 (2%)

Query: 44  GLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQ 103
           G+   +L  +  +G+EKP+ IQ +AI  I+ GRD+I  +++G+GKT  F + + + +  Q
Sbjct: 378 GISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQ 437

Query: 104 --VRETQ---ALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQH 158
             + E +   A+I+ PTRELA+QI K        + ++     GGT + E I +L  G  
Sbjct: 438 RSLEEGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVVCVYGGTGISEQIAELKRGAE 497

Query: 159 VVAGTPGRVFDMIRRRSLRT---RAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVV 215
           ++  TPGR+ DM+   S R    R +  +VLDEAD M + GF+ Q+  +   + P  Q V
Sbjct: 498 IIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIVDNVRPDRQTV 557

Query: 216 LISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTL 275
           + SAT P  +  +  + ++ PI + V    +    ++Q  + +E EE KF  L +L    
Sbjct: 558 MFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVIE-EEKKFLKLLELLGHY 616

Query: 276 TITQAVI-FCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLIST 334
             + +VI F + +   D L + +  A++   S+HG + Q +R+SI+ +F++G  ++L++T
Sbjct: 617 QESGSVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCKLLVAT 676

Query: 335 DVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDI 392
            V ARGLDV  + L++NY  PN+ E Y+HR GR+GR G KG A  F+  D  R   DI
Sbjct: 677 SVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQARYAGDI 734


>gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo
           sapiens]
          Length = 662

 Score =  210 bits (534), Expect = 2e-54
 Identities = 139/413 (33%), Positives = 215/413 (52%), Gaps = 32/413 (7%)

Query: 24  TKVEFETSEEVDVTPT----------FDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQII 73
           T + FE  +++ V  T          F  + + E ++  I    + +P+ +Q+ AI  I 
Sbjct: 156 TGINFEKYDDIPVEATGNNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIK 215

Query: 74  KGRDVIAQSQSGTGKTATFSISVLQCLDIQV---------------RETQ---ALILAPT 115
           + RD++A +Q+G+GKTA F + +L  +                   R  Q   +L+LAPT
Sbjct: 216 EKRDLMACAQTGSGKTAAFLLPILSQIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPT 275

Query: 116 RELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRS 175
           RELAVQI +          V+     GG ++G+ IR L+ G H++  TPGR+ DM+ R  
Sbjct: 276 RELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGK 335

Query: 176 LRTRAIKMLVLDEADEMLNKGFKEQIYDVYRY--LPP--ATQVVLISATLPHEILEMTNK 231
           +     K LVLDEAD ML+ GF+ QI  +     +PP      ++ SAT P EI  +   
Sbjct: 336 IGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARD 395

Query: 232 FMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVD 291
           F+ + I + V R   T E I Q  V VE  + +   L  L  T   +  ++F  TK+  D
Sbjct: 396 FLDEYIFLAVGRVGSTSENITQKVVWVEESDKRSFLLDLLNATGKDSLTLVFVETKKGAD 455

Query: 292 WLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIIN 351
            L + +    +  +S+HGD  Q++RE  + +FRSG S +L++T V ARGLD+  V  +IN
Sbjct: 456 SLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVIN 515

Query: 352 YDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMP 404
           +DLP++ E Y+HRIGR+GR G  G+A +F    +I I +D+         E+P
Sbjct: 516 FDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNINITKDLLDLLVEAKQEVP 568


>gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
           [Homo sapiens]
          Length = 660

 Score =  209 bits (531), Expect = 5e-54
 Identities = 141/414 (34%), Positives = 219/414 (52%), Gaps = 34/414 (8%)

Query: 24  TKVEFETSEEVDVTPT----------FDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQII 73
           T + FE  +++ V  T          F  + + E ++  I    + +P+ +Q+ AI  II
Sbjct: 154 TGINFEKYDDIPVEATGSNCPPHIENFSDIDMGEIIMGNIELTRYTRPTPVQKHAIP-II 212

Query: 74  KG-RDVIAQSQSGTGKTATFSISVLQCLDIQ--------VRETQ----------ALILAP 114
           KG RD++A +Q+G+GKTA F + +L  +           V+E            +L+LAP
Sbjct: 213 KGKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAVKENGRYGRRKQYPISLVLAP 272

Query: 115 TRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRR 174
           TRELAVQI +          V+     GG ++G+ IR L+ G H++  TPGR+ DM+ R 
Sbjct: 273 TRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERG 332

Query: 175 SLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRY--LPP--ATQVVLISATLPHEILEMTN 230
            +     K LVLDEAD ML+ GF+ QI  +     +PP      ++ SAT P EI  +  
Sbjct: 333 KIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLAR 392

Query: 231 KFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKV 290
            F+ + I + V R   T E I Q  V VE  + +   L  L  T + +  ++F  TK+  
Sbjct: 393 DFLDEYIFLAVGRVGSTSENITQKVVWVEDLDKRSFLLDILGATGSDSLTLVFVETKKGA 452

Query: 291 DWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLII 350
           D L + +    +  +S+HGD  Q++RE  + +FRSG S +L++T V ARGLD+  V  +I
Sbjct: 453 DSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVI 512

Query: 351 NYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMP 404
           N+DLP++ E Y+HRIGR+GR G  G+A +F    ++ I +D+         E+P
Sbjct: 513 NFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNEKNMNITKDLLDLLVEAKQEVP 566


>gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
           [Homo sapiens]
          Length = 660

 Score =  209 bits (531), Expect = 5e-54
 Identities = 141/414 (34%), Positives = 219/414 (52%), Gaps = 34/414 (8%)

Query: 24  TKVEFETSEEVDVTPT----------FDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQII 73
           T + FE  +++ V  T          F  + + E ++  I    + +P+ +Q+ AI  II
Sbjct: 154 TGINFEKYDDIPVEATGSNCPPHIENFSDIDMGEIIMGNIELTRYTRPTPVQKHAIP-II 212

Query: 74  KG-RDVIAQSQSGTGKTATFSISVLQCLDIQ--------VRETQ----------ALILAP 114
           KG RD++A +Q+G+GKTA F + +L  +           V+E            +L+LAP
Sbjct: 213 KGKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAVKENGRYGRRKQYPISLVLAP 272

Query: 115 TRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRR 174
           TRELAVQI +          V+     GG ++G+ IR L+ G H++  TPGR+ DM+ R 
Sbjct: 273 TRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERG 332

Query: 175 SLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRY--LPP--ATQVVLISATLPHEILEMTN 230
            +     K LVLDEAD ML+ GF+ QI  +     +PP      ++ SAT P EI  +  
Sbjct: 333 KIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLAR 392

Query: 231 KFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKV 290
            F+ + I + V R   T E I Q  V VE  + +   L  L  T + +  ++F  TK+  
Sbjct: 393 DFLDEYIFLAVGRVGSTSENITQKVVWVEDLDKRSFLLDILGATGSDSLTLVFVETKKGA 452

Query: 291 DWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLII 350
           D L + +    +  +S+HGD  Q++RE  + +FRSG S +L++T V ARGLD+  V  +I
Sbjct: 453 DSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVI 512

Query: 351 NYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMP 404
           N+DLP++ E Y+HRIGR+GR G  G+A +F    ++ I +D+         E+P
Sbjct: 513 NFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNEKNMNITKDLLDLLVEAKQEVP 566


>gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo
           sapiens]
          Length = 648

 Score =  208 bits (530), Expect = 6e-54
 Identities = 137/403 (33%), Positives = 219/403 (54%), Gaps = 15/403 (3%)

Query: 3   TTATMATSGSARKRLLKEE-DMTKVEFETSEEVDV---TPTFD-TMGLREDLLRGIYAYG 57
           +TAT A S        KE  ++T  + +  E+  +   T TFD       +++  I   G
Sbjct: 202 STATSAMSKVEADSWRKENFNITWDDLKDGEKRPIPNPTCTFDDAFQCYPEVMENIKKAG 261

Query: 58  FEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSIS-----VLQ-CLDIQVRETQALI 111
           F+KP+ IQ +A   +++G D+I  +Q+GTGKT  + +      VLQ  L  Q      L+
Sbjct: 262 FQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLCYLMPGFIHLVLQPSLKGQRNRPGMLV 321

Query: 112 LAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMI 171
           L PTRELA+Q++ G      Y  ++     GG N  E I +L  G  ++  TPGR+ D+ 
Sbjct: 322 LTPTRELALQVE-GECCKYSYKGLRSVCVYGGGNRDEQIEELKKGVDIIIATPGRLNDLQ 380

Query: 172 RRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNK 231
               +  + I  LVLDEAD+ML+ GF+ QI  +   + P  Q V+ SAT PH +  +   
Sbjct: 381 MSNFVNLKNITYLVLDEADKMLDMGFEPQIMKILLDVRPDRQTVMTSATWPHSVHRLAQS 440

Query: 232 FMTDPIRILVKR-DELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVI-FCNTKRK 289
           ++ +P+ + V   D + +  +KQ  +    EE K+  +     +++ T  VI F + K  
Sbjct: 441 YLKEPMIVYVGTLDLVAVSSVKQNIIVTTEEE-KWSHMQTFLQSMSSTDKVIVFVSRKAV 499

Query: 290 VDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLI 349
            D L+  +   N +V S+HGD  Q++RE  ++ F++G  R+LI+TD+ +RGLDV  V+ +
Sbjct: 500 ADHLSSDLILGNISVESLHGDREQRDREKALENFKTGKVRILIATDLASRGLDVHDVTHV 559

Query: 350 INYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDI 392
            N+D P N E Y+HRIGR+GR GR GV+I  +  +D R+  ++
Sbjct: 560 YNFDFPRNIEEYVHRIGRTGRAGRTGVSITTLTRNDWRVASEL 602


>gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo
           sapiens]
          Length = 619

 Score =  208 bits (530), Expect = 6e-54
 Identities = 119/358 (33%), Positives = 205/358 (57%), Gaps = 7/358 (1%)

Query: 40  FDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQC 99
           F+   L E L   +   G+E P+ IQ + I   + GRD++A + +G+GKTA F + V+  
Sbjct: 205 FEHCSLPEVLNHNLKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLPVIMR 264

Query: 100 LDIQVRETQALILAPTRELAVQIQKGLLALGDYM-NVQCHACIGGTNVGEDIRKLDYGQH 158
              + +   ALIL PTRELA+QI++    L   +  ++    +GG  +   + +L     
Sbjct: 265 ALFESKTPSALILTPTRELAIQIERQAKELMSGLPRMKTVLLVGGLPLPPQLYRLQQHVK 324

Query: 159 VVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLIS 218
           V+  TPGR+ D+I++ S+    +K++V+DEAD ML  GF++Q+ D+   +P   Q +L+S
Sbjct: 325 VIIATPGRLLDIIKQSSVELCGVKIVVVDEADTMLKMGFQQQVLDILENIPNDCQTILVS 384

Query: 219 ATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVE---REEWKFDTLCDLYDTL 275
           AT+P  I ++ ++ + +P+RI+     L    ++Q  + VE   +++  F+ L D    L
Sbjct: 385 ATIPTSIEQLASQLLHNPVRIITGEKNLPCANVRQIILWVEDPAKKKKLFEILND--KKL 442

Query: 276 TITQAVIFCNTKRKVDWLTEKMREANFTVS-SMHGDMPQKERESIMKEFRSGASRVLIST 334
                ++F + K   D L+E +++     S S+H +  Q ER++I+K    G   V++ST
Sbjct: 443 FKPPVLVFVDCKLGADLLSEAVQKITGLKSISIHSEKSQIERKNILKGLLEGDYEVVVST 502

Query: 335 DVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDI 392
            V  RGLD+  V L++N+D+P++ + Y+H+IGR GR G+ G AI F+ N+  R+  DI
Sbjct: 503 GVLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAITFINNNSKRLFWDI 560


>gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2
           [Homo sapiens]
          Length = 881

 Score =  206 bits (523), Expect = 4e-53
 Identities = 120/360 (33%), Positives = 195/360 (54%), Gaps = 5/360 (1%)

Query: 40  FDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQC 99
           F +MGL   + +GI   G++ P+ IQ++ I  I+ G+DV+A +++G+GKTA F + + + 
Sbjct: 98  FQSMGLSYPVFKGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACFLLPMFER 157

Query: 100 LDIQVRET--QALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQ 157
           L     +T  +ALIL+PTRELA+Q  K    LG +  ++    +GG  + +    L    
Sbjct: 158 LKTHSAQTGARALILSPTRELALQTLKFTKELGKFTGLKTALILGGDRMEDQFAALHENP 217

Query: 158 HVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLI 217
            ++  TPGR+  +    SL+ ++++ +V DEAD +   GF EQ+ ++   LP   Q VL 
Sbjct: 218 DIIIATPGRLVHVAVEMSLKLQSVEYVVFDEADRLFEMGFAEQLQEIIARLPGGHQTVLF 277

Query: 218 SATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLT- 276
           SATLP  ++E     +T+P+ I +  D    E +K  F  V RE+ K   L  L   +  
Sbjct: 278 SATLPKLLVEFARAGLTEPVLIRLDVDTKLNEQLKTSFFLV-REDTKAAVLLHLLHNVVR 336

Query: 277 -ITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTD 335
              Q V+F  TK   ++LTE +     + + ++  +    R+  + +F  G    LI TD
Sbjct: 337 PQDQTVVFVATKHHAEYLTELLTTQRVSCAHIYSALDPTARKINLAKFTLGKCSTLIVTD 396

Query: 336 VWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQY 395
           + ARGLD+P +  +INY  P   +L++HR+GR  R GR G A + V  D+I  L D+  +
Sbjct: 397 LAARGLDIPLLDNVINYSFPAKGKLFLHRVGRVARAGRSGTAYSLVAPDEIPYLLDLHLF 456


>gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1
           [Homo sapiens]
          Length = 882

 Score =  206 bits (523), Expect = 4e-53
 Identities = 120/360 (33%), Positives = 195/360 (54%), Gaps = 5/360 (1%)

Query: 40  FDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQC 99
           F +MGL   + +GI   G++ P+ IQ++ I  I+ G+DV+A +++G+GKTA F + + + 
Sbjct: 98  FQSMGLSYPVFKGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACFLLPMFER 157

Query: 100 LDIQVRET--QALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQ 157
           L     +T  +ALIL+PTRELA+Q  K    LG +  ++    +GG  + +    L    
Sbjct: 158 LKTHSAQTGARALILSPTRELALQTLKFTKELGKFTGLKTALILGGDRMEDQFAALHENP 217

Query: 158 HVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLI 217
            ++  TPGR+  +    SL+ ++++ +V DEAD +   GF EQ+ ++   LP   Q VL 
Sbjct: 218 DIIIATPGRLVHVAVEMSLKLQSVEYVVFDEADRLFEMGFAEQLQEIIARLPGGHQTVLF 277

Query: 218 SATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLT- 276
           SATLP  ++E     +T+P+ I +  D    E +K  F  V RE+ K   L  L   +  
Sbjct: 278 SATLPKLLVEFARAGLTEPVLIRLDVDTKLNEQLKTSFFLV-REDTKAAVLLHLLHNVVR 336

Query: 277 -ITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTD 335
              Q V+F  TK   ++LTE +     + + ++  +    R+  + +F  G    LI TD
Sbjct: 337 PQDQTVVFVATKHHAEYLTELLTTQRVSCAHIYSALDPTARKINLAKFTLGKCSTLIVTD 396

Query: 336 VWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQY 395
           + ARGLD+P +  +INY  P   +L++HR+GR  R GR G A + V  D+I  L D+  +
Sbjct: 397 LAARGLDIPLLDNVINYSFPAKGKLFLHRVGRVARAGRSGTAYSLVAPDEIPYLLDLHLF 456


>gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo
           sapiens]
          Length = 796

 Score =  205 bits (521), Expect = 7e-53
 Identities = 120/385 (31%), Positives = 209/385 (54%), Gaps = 6/385 (1%)

Query: 14  RKRLLKEEDMTKVEFETSEEVDVTPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQII 73
           RK+  K+       FE + + D   +F  M L   LL+ I A GF++P+ IQ+  I   +
Sbjct: 194 RKKKKKKGQEAGGFFEDASQYDENLSFQDMNLSRPLLKAITAMGFKQPTPIQKACIPVGL 253

Query: 74  KGRDVIAQSQSGTGKTATFSISVLQCLDIQVRE---TQALILAPTRELAVQIQKGLLALG 130
            G+D+ A + +GTGKTA F++ VL+ L  + R+   T+ L+L PTREL +Q+      L 
Sbjct: 254 LGKDICACAATGTGKTAAFALPVLERLIYKPRQAPVTRVLVLVPTRELGIQVHSVTRQLA 313

Query: 131 DYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRR-RSLRTRAIKMLVLDEA 189
            + N+     +GG +V      L     ++  TPGR+ D +    S    +I++L+LDEA
Sbjct: 314 QFCNITTCLAVGGLDVKSQEAALRAAPDILIATPGRLIDHLHNCPSFHLSSIEVLILDEA 373

Query: 190 DEMLNKGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRILVKRDELTLE 249
           D ML++ F+EQ+ ++ R      Q +L SAT+  E+ ++ +  + +P+RI V  +     
Sbjct: 374 DRMLDEYFEEQMKEIIRMCSHHRQTMLFSATMTDEVKDLASVSLKNPVRIFVNSNTDVAP 433

Query: 250 GIKQFFVAVE-REEWKFDTLCDLYDTLTITQAV-IFCNTKRKVDWLTEKMREANFTVSSM 307
            ++Q F+ +    E   + +     T T T  V +F  TK++   +   +      V  +
Sbjct: 434 FLRQEFIRIRPNREGDREAIVAALLTRTFTDHVMLFTQTKKQAHRMHILLGLMGLQVGEL 493

Query: 308 HGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGR 367
           HG++ Q +R   ++ F+     +L++TDV ARGLD+  V  +IN+ +PN  + Y+HR+GR
Sbjct: 494 HGNLSQTQRLEALRRFKDEQIDILVATDVAARGLDIEGVKTVINFTMPNTIKHYVHRVGR 553

Query: 368 SGRYGRKGVAINFVKNDDIRILRDI 392
           + R GR G +++ V  D+ ++L++I
Sbjct: 554 TARAGRAGRSVSLVGEDERKMLKEI 578


>gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens]
          Length = 731

 Score =  201 bits (510), Expect = 1e-51
 Identities = 121/343 (35%), Positives = 181/343 (52%), Gaps = 8/343 (2%)

Query: 58  FEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQA-----LIL 112
           F +P+ IQ +     + GRD++  +Q+G+GKT  + +  +  ++ Q    +      L+L
Sbjct: 191 FTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGPICLVL 250

Query: 113 APTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIR 172
           APTRELA Q+Q+     G    ++     GG   G  IR L+ G  +   TPGR+ D + 
Sbjct: 251 APTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLE 310

Query: 173 RRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKF 232
                 R    LVLDEAD ML+ GF+ QI  +   + P  Q ++ SAT P E+ ++   F
Sbjct: 311 SGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDF 370

Query: 233 MTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTI---TQAVIFCNTKRK 289
           + D  +I V   EL+        V V  E  K   L  L + +      + +IF  TKR+
Sbjct: 371 LRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKTIIFVETKRR 430

Query: 290 VDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLI 349
            D LT +MR   +    +HGD  Q ER+ ++ EFRSG + +LI+TDV +RGLDV  V  +
Sbjct: 431 CDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFV 490

Query: 350 INYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDI 392
           INYD PN+ E Y+HRIGR+ R   KG A  F    +++  R++
Sbjct: 491 INYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQAREL 533


>gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens]
          Length = 729

 Score =  201 bits (510), Expect = 1e-51
 Identities = 121/343 (35%), Positives = 181/343 (52%), Gaps = 8/343 (2%)

Query: 58  FEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQA-----LIL 112
           F +P+ IQ +     + GRD++  +Q+G+GKT  + +  +  ++ Q    +      L+L
Sbjct: 191 FTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGPICLVL 250

Query: 113 APTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIR 172
           APTRELA Q+Q+     G    ++     GG   G  IR L+ G  +   TPGR+ D + 
Sbjct: 251 APTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLE 310

Query: 173 RRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKF 232
                 R    LVLDEAD ML+ GF+ QI  +   + P  Q ++ SAT P E+ ++   F
Sbjct: 311 SGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDF 370

Query: 233 MTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTI---TQAVIFCNTKRK 289
           + D  +I V   EL+        V V  E  K   L  L + +      + +IF  TKR+
Sbjct: 371 LRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKTIIFVETKRR 430

Query: 290 VDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLI 349
            D LT +MR   +    +HGD  Q ER+ ++ EFRSG + +LI+TDV +RGLDV  V  +
Sbjct: 431 CDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFV 490

Query: 350 INYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDI 392
           INYD PN+ E Y+HRIGR+ R   KG A  F    +++  R++
Sbjct: 491 INYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQAREL 533


>gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens]
          Length = 614

 Score =  196 bits (497), Expect = 4e-50
 Identities = 118/343 (34%), Positives = 183/343 (53%), Gaps = 8/343 (2%)

Query: 58  FEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQA-----LIL 112
           F +P+AIQ +     + G D++  +Q+G+GKT ++ +  +  ++ Q    +      L+L
Sbjct: 114 FTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVL 173

Query: 113 APTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIR 172
           APTRELA Q+Q+          ++     GG   G  IR L+ G  +   TPGR+ D + 
Sbjct: 174 APTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLE 233

Query: 173 RRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKF 232
                 R    LVLDEAD ML+ GF+ QI  +   + P  Q ++ SAT P E+ ++   F
Sbjct: 234 CGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDF 293

Query: 233 MTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTI---TQAVIFCNTKRK 289
           + D I I +   EL+        V V  +  K + L  L + +      + ++F  TKR+
Sbjct: 294 LKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKRR 353

Query: 290 VDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLI 349
            D LT KMR   +    +HGD  Q+ER+ ++ EF+ G + +LI+TDV +RGLDV  V  +
Sbjct: 354 CDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFV 413

Query: 350 INYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDI 392
           INYD PN+ E YIHRIGR+ R  + G A  F   ++I+ + D+
Sbjct: 414 INYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDL 456


>gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo
           sapiens]
          Length = 783

 Score =  194 bits (493), Expect = 1e-49
 Identities = 126/391 (32%), Positives = 208/391 (53%), Gaps = 21/391 (5%)

Query: 20  EEDMTKVEFETSEEVDVTPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVI 79
           EE  +++E E   E      F    + E+ ++ +   G      IQ +    +  G+D+I
Sbjct: 169 EESNSEIEQEIPVE-QKEGAFSNFPISEETIKLLKGRGVTFLFPIQAKTFHHVYSGKDLI 227

Query: 80  AQSQSGTGKTATFSISVLQCLDIQV------RETQALILAPTRELAVQIQKGLLALGDYM 133
           AQ+++GTGKT +F+I +++ L  ++      R  Q L+LAPTRELA Q+ K    +   +
Sbjct: 228 AQARTGTGKTFSFAIPLIEKLHGELQDRKRGRAPQVLVLAPTRELANQVSKDFSDITKKL 287

Query: 134 NVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEML 193
           +V C    GGT  G    ++  G  ++ GTPGR+ D I+   L    +K +VLDE D+ML
Sbjct: 288 SVACF--YGGTPYGGQFERMRNGIDILVGTPGRIKDHIQNGKLDLTKLKHVVLDEVDQML 345

Query: 194 NKGFKEQIYDVYRYL-----PPATQVVLISATLPHEILEMTNKFMT---DPIRILVKRDE 245
           + GF +Q+ ++             Q +L SAT PH +  +  K+M    + + ++ K+ +
Sbjct: 346 DMGFADQVEEILSVAYKKDSEDNPQTLLFSATCPHWVFNVAKKYMKSTYEQVDLIGKKTQ 405

Query: 246 LTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQA--VIFCNTKRKVDWLTEKMREANFT 303
            T   ++   +     + +   + D+    +  Q   +IFC TK++   L++        
Sbjct: 406 KTAITVEHLAIKCHWTQ-RAAVIGDVIRVYSGHQGRTIIFCETKKEAQELSQNSAIKQ-D 463

Query: 304 VSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIH 363
             S+HGD+PQK+RE  +K FR+G+  VL++T+V ARGLD+P+V L+I    P + E YIH
Sbjct: 464 AQSLHGDIPQKQREITLKGFRNGSFGVLVATNVAARGLDIPEVDLVIQSSPPKDVESYIH 523

Query: 364 RIGRSGRYGRKGVAINFVKNDDIRILRDIEQ 394
           R GR+GR GR GV I F ++ +   L  +EQ
Sbjct: 524 RSGRTGRAGRTGVCICFYQHKEEYQLVQVEQ 554


>gi|21071032 DEAD-box protein abstrakt [Homo sapiens]
          Length = 622

 Score =  192 bits (488), Expect = 5e-49
 Identities = 123/371 (33%), Positives = 194/371 (52%), Gaps = 19/371 (5%)

Query: 39  TFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQ 98
           +F  M     +LRG+   G   P+ IQ + I  I+ GRD+I  + +G+GKT  F++ V+ 
Sbjct: 182 SFKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGRDMIGIAFTGSGKTLVFTLPVIM 241

Query: 99  -CLDIQVR-------ETQALILAPTRELAVQIQK------GLLALGDYMNVQCHACIGGT 144
            CL+ + R           LI+ P+RELA Q          LL       ++C  CIGG 
Sbjct: 242 FCLEQEKRLPFSKREGPYGLIICPSRELARQTHGILEYYCRLLQEDSSPLLRCALCIGGM 301

Query: 145 NVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDV 204
           +V E +  + +G H++  TPGR+ D+++++ +     + L LDEAD M++ GF+  I  +
Sbjct: 302 SVKEQMETIRHGVHMMVATPGRLMDLLQKKMVSLDICRYLALDEADRMIDMGFEGDIRTI 361

Query: 205 YRYLPPATQVVLISATLPHEILEMTNKFMTDPIRILVKR-DELTLEGIKQFFVAVEREEW 263
           + Y     Q +L SAT+P +I       +  P+ I V R    +L+ I++  V   +EE 
Sbjct: 362 FSYFKGQRQTLLFSATMPKKIQNFAKSALVKPVTINVGRAGAASLDVIQE--VEYVKEEA 419

Query: 264 KFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEF 323
           K   L +     T    +IF   K  VD + E +        ++HG   Q+ER   ++ F
Sbjct: 420 KMVYLLECLQK-TPPPVLIFAEKKADVDAIHEYLLLKGVEAVAIHGGKDQEERTKAIEAF 478

Query: 324 RSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFV-K 382
           R G   VL++TDV ++GLD P +  +INYD+P   E Y+HRIGR+GR G  G+A  F+ K
Sbjct: 479 REGKKDVLVATDVASKGLDFPAIQHVINYDMPEEIENYVHRIGRTGRSGNTGIATTFINK 538

Query: 383 NDDIRILRDIE 393
             D  +L D++
Sbjct: 539 ACDESVLMDLK 549


>gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3
           [Homo sapiens]
          Length = 724

 Score =  191 bits (485), Expect = 1e-48
 Identities = 125/404 (30%), Positives = 218/404 (53%), Gaps = 23/404 (5%)

Query: 22  DMTKVEFETSEEVDVTPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQ 81
           D   VE    +      TF+   L + L   I   G+ K + +Q+ +I  I+ GRD++A 
Sbjct: 272 DTILVEVSGHDAPPAILTFEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMAC 331

Query: 82  SQSGTGKTATFSISVLQCLDI---------QVRETQALILAPTRELAVQIQKGLLALGDY 132
           +Q+G+GKTA F + +L  +           +++E + +I+APTREL  QI          
Sbjct: 332 AQTGSGKTAAFLLPILAHMMHDGITASRFKELQEPECIIVAPTRELVNQIYLEARKFSFG 391

Query: 133 MNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEM 192
             V+     GGT +G  IR++  G +++  TPGR+ D+I +  +  + IK LVLDEAD M
Sbjct: 392 TCVRAVVIYGGTQLGHSIRQIVQGCNILCATPGRLMDIIGKEKIGLKQIKYLVLDEADRM 451

Query: 193 LNKGFKEQIYDVYRY--LPPATQ--VVLISATLPHEILEMTNKFM-TDPIRILVKRDELT 247
           L+ GF  ++  +     +P   Q   ++ SAT P EI  +  +F+ ++ + + V +    
Sbjct: 452 LDMGFGPEMKKLISCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVGGA 511

Query: 248 LEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSM 307
              ++Q  + V +   K + L ++   +   + ++F  TK+K D++   + +   + +S+
Sbjct: 512 CRDVQQTVLQVGQFS-KREKLVEILRNIGDERTMVFVETKKKADFIATFLCQEKISTTSI 570

Query: 308 HGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGR 367
           HGD  Q+ERE  + +FR G   VL++T V ARGLD+  V  +IN+DLP+  + Y+HRIGR
Sbjct: 571 HGDREQREREQALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGR 630

Query: 368 SGRYGRKGVAINF--VKNDD------IRILRDIEQYYSTQIDEM 403
           +GR G  G AI+F  +++D+      +++L D +Q     ++E+
Sbjct: 631 TGRCGNTGRAISFFDLESDNHLAQPLVKVLTDAQQDVPAWLEEI 674


>gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1
           [Homo sapiens]
          Length = 724

 Score =  191 bits (485), Expect = 1e-48
 Identities = 125/404 (30%), Positives = 218/404 (53%), Gaps = 23/404 (5%)

Query: 22  DMTKVEFETSEEVDVTPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQ 81
           D   VE    +      TF+   L + L   I   G+ K + +Q+ +I  I+ GRD++A 
Sbjct: 272 DTILVEVSGHDAPPAILTFEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMAC 331

Query: 82  SQSGTGKTATFSISVLQCLDI---------QVRETQALILAPTRELAVQIQKGLLALGDY 132
           +Q+G+GKTA F + +L  +           +++E + +I+APTREL  QI          
Sbjct: 332 AQTGSGKTAAFLLPILAHMMHDGITASRFKELQEPECIIVAPTRELVNQIYLEARKFSFG 391

Query: 133 MNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEM 192
             V+     GGT +G  IR++  G +++  TPGR+ D+I +  +  + IK LVLDEAD M
Sbjct: 392 TCVRAVVIYGGTQLGHSIRQIVQGCNILCATPGRLMDIIGKEKIGLKQIKYLVLDEADRM 451

Query: 193 LNKGFKEQIYDVYRY--LPPATQ--VVLISATLPHEILEMTNKFM-TDPIRILVKRDELT 247
           L+ GF  ++  +     +P   Q   ++ SAT P EI  +  +F+ ++ + + V +    
Sbjct: 452 LDMGFGPEMKKLISCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVGGA 511

Query: 248 LEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSM 307
              ++Q  + V +   K + L ++   +   + ++F  TK+K D++   + +   + +S+
Sbjct: 512 CRDVQQTVLQVGQFS-KREKLVEILRNIGDERTMVFVETKKKADFIATFLCQEKISTTSI 570

Query: 308 HGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGR 367
           HGD  Q+ERE  + +FR G   VL++T V ARGLD+  V  +IN+DLP+  + Y+HRIGR
Sbjct: 571 HGDREQREREQALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGR 630

Query: 368 SGRYGRKGVAINF--VKNDD------IRILRDIEQYYSTQIDEM 403
           +GR G  G AI+F  +++D+      +++L D +Q     ++E+
Sbjct: 631 TGRCGNTGRAISFFDLESDNHLAQPLVKVLTDAQQDVPAWLEEI 674


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.136    0.388 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,448,065
Number of Sequences: 37866
Number of extensions: 539727
Number of successful extensions: 1494
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 67
Number of HSP's successfully gapped in prelim test: 40
Number of HSP's that attempted gapping in prelim test: 1261
Number of HSP's gapped (non-prelim): 123
length of query: 411
length of database: 18,247,518
effective HSP length: 105
effective length of query: 306
effective length of database: 14,271,588
effective search space: 4367105928
effective search space used: 4367105928
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.