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Search of human proteins with 7661878
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7661878 kinesin family member 14 [Homo sapiens]
(1648 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7661878 kinesin family member 14 [Homo sapiens] 3235 0.0
gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens] 496 e-140
gi|41393563 kinesin family member 1B isoform b [Homo sapiens] 495 e-139
gi|19924175 axonal transport of synaptic vesicles [Homo sapiens] 480 e-135
gi|46852172 kinesin family member 13B [Homo sapiens] 469 e-132
gi|157738629 kinesin family member 13A isoform d [Homo sapiens] 468 e-131
gi|157738627 kinesin family member 13A isoform c [Homo sapiens] 468 e-131
gi|157738625 kinesin family member 13A isoform b [Homo sapiens] 468 e-131
gi|157738621 kinesin family member 13A isoform a [Homo sapiens] 468 e-131
gi|41393559 kinesin family member 1B isoform alpha [Homo sapiens] 468 e-131
gi|40254834 kinesin family member 1C [Homo sapiens] 453 e-127
gi|239756270 PREDICTED: StAR-related lipid transfer (START) doma... 318 2e-86
gi|239750815 PREDICTED: StAR-related lipid transfer (START) doma... 318 2e-86
gi|239745175 PREDICTED: StAR-related lipid transfer (START) doma... 318 2e-86
gi|4758646 kinesin family member 3B [Homo sapiens] 268 3e-71
gi|150010604 kinesin family member 4B [Homo sapiens] 263 1e-69
gi|116686122 kinesin family member 4 [Homo sapiens] 260 9e-69
gi|170784809 kinesin family member 17 isoform b [Homo sapiens] 260 9e-69
gi|170784807 kinesin family member 17 isoform a [Homo sapiens] 260 9e-69
gi|46852174 kinesin family member 3A [Homo sapiens] 245 2e-64
gi|41352705 kinesin family member 3C [Homo sapiens] 243 1e-63
gi|71061468 centromere protein E [Homo sapiens] 237 6e-62
gi|38569484 kinesin family member 21A [Homo sapiens] 237 6e-62
gi|83716024 kinesin family member 21B [Homo sapiens] 234 4e-61
gi|9910266 kinesin family member 15 [Homo sapiens] 228 5e-59
gi|13699824 kinesin family member 11 [Homo sapiens] 225 3e-58
gi|30794488 kinesin family member 27 [Homo sapiens] 221 5e-57
gi|122937289 kinesin family member 18B [Homo sapiens] 216 1e-55
gi|4758650 kinesin family member 5C [Homo sapiens] 214 7e-55
gi|148612831 kinesin family member 18A [Homo sapiens] 213 2e-54
>gi|7661878 kinesin family member 14 [Homo sapiens]
Length = 1648
Score = 3235 bits (8387), Expect = 0.0
Identities = 1648/1648 (100%), Positives = 1648/1648 (100%)
Query: 1 MSLHSTHNRNNSGDILDIPSSQNSSSLNALTHSSRLKLHLKSDMSECENDDPLLRSAGKV 60
MSLHSTHNRNNSGDILDIPSSQNSSSLNALTHSSRLKLHLKSDMSECENDDPLLRSAGKV
Sbjct: 1 MSLHSTHNRNNSGDILDIPSSQNSSSLNALTHSSRLKLHLKSDMSECENDDPLLRSAGKV 60
Query: 61 RDINRTYVISASRKTADMPLTPNPVGRLALQRRTTRNKESSLLVSELEDTTEKTAETRLT 120
RDINRTYVISASRKTADMPLTPNPVGRLALQRRTTRNKESSLLVSELEDTTEKTAETRLT
Sbjct: 61 RDINRTYVISASRKTADMPLTPNPVGRLALQRRTTRNKESSLLVSELEDTTEKTAETRLT 120
Query: 121 LQRRAKTDSAEKWKTAEIDSVKMTLNVGGETENNGVSKESRTNVRIVNNAKNSFVASSVP 180
LQRRAKTDSAEKWKTAEIDSVKMTLNVGGETENNGVSKESRTNVRIVNNAKNSFVASSVP
Sbjct: 121 LQRRAKTDSAEKWKTAEIDSVKMTLNVGGETENNGVSKESRTNVRIVNNAKNSFVASSVP 180
Query: 181 LDEDPQVIEMMADKKYKETFSAPSRANENVALKYSSNRPPIASLSQTEVVRSGHLTTKPT 240
LDEDPQVIEMMADKKYKETFSAPSRANENVALKYSSNRPPIASLSQTEVVRSGHLTTKPT
Sbjct: 181 LDEDPQVIEMMADKKYKETFSAPSRANENVALKYSSNRPPIASLSQTEVVRSGHLTTKPT 240
Query: 241 QSKLDIKVLGTGNLYHRSIGKEIAKTSNKFGSLEKRTPTKCTTEHKLTTKCSLPQLKSPA 300
QSKLDIKVLGTGNLYHRSIGKEIAKTSNKFGSLEKRTPTKCTTEHKLTTKCSLPQLKSPA
Sbjct: 241 QSKLDIKVLGTGNLYHRSIGKEIAKTSNKFGSLEKRTPTKCTTEHKLTTKCSLPQLKSPA 300
Query: 301 PSILKNRMSNLQVKQRPKSSFLANKQERSAENTILPEEETVVQNTSAGKDPLKVENSQVT 360
PSILKNRMSNLQVKQRPKSSFLANKQERSAENTILPEEETVVQNTSAGKDPLKVENSQVT
Sbjct: 301 PSILKNRMSNLQVKQRPKSSFLANKQERSAENTILPEEETVVQNTSAGKDPLKVENSQVT 360
Query: 361 VAVRVRPFTKREKIEKASQVVFMSGKEITVEHPDTKQVYNFIYDVSFWSFDECHPHYASQ 420
VAVRVRPFTKREKIEKASQVVFMSGKEITVEHPDTKQVYNFIYDVSFWSFDECHPHYASQ
Sbjct: 361 VAVRVRPFTKREKIEKASQVVFMSGKEITVEHPDTKQVYNFIYDVSFWSFDECHPHYASQ 420
Query: 421 TTVYEKLAAPLLERAFEGFNTCLFAYGQTGSGKSYTMMGFSEEPGIIPRFCEDLFSQVAR 480
TTVYEKLAAPLLERAFEGFNTCLFAYGQTGSGKSYTMMGFSEEPGIIPRFCEDLFSQVAR
Sbjct: 421 TTVYEKLAAPLLERAFEGFNTCLFAYGQTGSGKSYTMMGFSEEPGIIPRFCEDLFSQVAR 480
Query: 481 KQTQEVSYHIEMSFFEVYNEKIHDLLVCKDENGQRKQPLRVREHPVYGPYVEALSMNIVS 540
KQTQEVSYHIEMSFFEVYNEKIHDLLVCKDENGQRKQPLRVREHPVYGPYVEALSMNIVS
Sbjct: 481 KQTQEVSYHIEMSFFEVYNEKIHDLLVCKDENGQRKQPLRVREHPVYGPYVEALSMNIVS 540
Query: 541 SYADIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTKTEFVEGEEHDHRITSRIN 600
SYADIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTKTEFVEGEEHDHRITSRIN
Sbjct: 541 SYADIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTKTEFVEGEEHDHRITSRIN 600
Query: 601 LIDLAGSERCSTAHTNGDRLKEGVSINKSLLTLGKVISALSEQANQRSVFIPYRESVLTW 660
LIDLAGSERCSTAHTNGDRLKEGVSINKSLLTLGKVISALSEQANQRSVFIPYRESVLTW
Sbjct: 601 LIDLAGSERCSTAHTNGDRLKEGVSINKSLLTLGKVISALSEQANQRSVFIPYRESVLTW 660
Query: 661 LLKESLGGNSKTAMIATISPAASNIEETLSTLRYANQARLIVNIAKVNEDMNAKLIRELK 720
LLKESLGGNSKTAMIATISPAASNIEETLSTLRYANQARLIVNIAKVNEDMNAKLIRELK
Sbjct: 661 LLKESLGGNSKTAMIATISPAASNIEETLSTLRYANQARLIVNIAKVNEDMNAKLIRELK 720
Query: 721 AEIAKLKAAQRNSRNIDPERYRLCRQEITSLRMKLHQQERDMAEMQRVWKEKFEQAEKRK 780
AEIAKLKAAQRNSRNIDPERYRLCRQEITSLRMKLHQQERDMAEMQRVWKEKFEQAEKRK
Sbjct: 721 AEIAKLKAAQRNSRNIDPERYRLCRQEITSLRMKLHQQERDMAEMQRVWKEKFEQAEKRK 780
Query: 781 LQETKELQKAGIMFQMDNHLPNLVNLNEDPQLSEMLLYMIKEGTTTVGKYKPNSSHDIQL 840
LQETKELQKAGIMFQMDNHLPNLVNLNEDPQLSEMLLYMIKEGTTTVGKYKPNSSHDIQL
Sbjct: 781 LQETKELQKAGIMFQMDNHLPNLVNLNEDPQLSEMLLYMIKEGTTTVGKYKPNSSHDIQL 840
Query: 841 SGVLIADDHCTIKNFGGTVSIIPVGEAKTYVNGKHILEITVLRHGDRVILGGDHYFRFNH 900
SGVLIADDHCTIKNFGGTVSIIPVGEAKTYVNGKHILEITVLRHGDRVILGGDHYFRFNH
Sbjct: 841 SGVLIADDHCTIKNFGGTVSIIPVGEAKTYVNGKHILEITVLRHGDRVILGGDHYFRFNH 900
Query: 901 PVEVQKGKRPSGRDTPISEGPKDFEFAKNELLMAQRSQLEAEIKEAQLKAKEEMMQGIQI 960
PVEVQKGKRPSGRDTPISEGPKDFEFAKNELLMAQRSQLEAEIKEAQLKAKEEMMQGIQI
Sbjct: 901 PVEVQKGKRPSGRDTPISEGPKDFEFAKNELLMAQRSQLEAEIKEAQLKAKEEMMQGIQI 960
Query: 961 AKEMAQQELSSQKAAYESKIKALEAELREESQRKKMQEINNQKANHKIEELEKAKQHLEQ 1020
AKEMAQQELSSQKAAYESKIKALEAELREESQRKKMQEINNQKANHKIEELEKAKQHLEQ
Sbjct: 961 AKEMAQQELSSQKAAYESKIKALEAELREESQRKKMQEINNQKANHKIEELEKAKQHLEQ 1020
Query: 1021 EIYVNKKRLEMETLATKQALEDHSIRHARILEALETEKQKIAKEVQILQQNRNNRDKTFT 1080
EIYVNKKRLEMETLATKQALEDHSIRHARILEALETEKQKIAKEVQILQQNRNNRDKTFT
Sbjct: 1021 EIYVNKKRLEMETLATKQALEDHSIRHARILEALETEKQKIAKEVQILQQNRNNRDKTFT 1080
Query: 1081 VQTTWSSMKLSMMIQEANAISSKLKTYYVFGRHDISDKSSSDTSIRVRNLKLGISTFWSL 1140
VQTTWSSMKLSMMIQEANAISSKLKTYYVFGRHDISDKSSSDTSIRVRNLKLGISTFWSL
Sbjct: 1081 VQTTWSSMKLSMMIQEANAISSKLKTYYVFGRHDISDKSSSDTSIRVRNLKLGISTFWSL 1140
Query: 1141 EKFESKLAAMKELYESNGSNRGEDAFCDPEDEWEPDITDAPVSSLSRRRSRSLMKNRRIS 1200
EKFESKLAAMKELYESNGSNRGEDAFCDPEDEWEPDITDAPVSSLSRRRSRSLMKNRRIS
Sbjct: 1141 EKFESKLAAMKELYESNGSNRGEDAFCDPEDEWEPDITDAPVSSLSRRRSRSLMKNRRIS 1200
Query: 1201 GCLHDIQVHPIKNLHSSHSSGLMDKSSTIYSNSAESFLPGICKELIGSSLDFFGQSYDEE 1260
GCLHDIQVHPIKNLHSSHSSGLMDKSSTIYSNSAESFLPGICKELIGSSLDFFGQSYDEE
Sbjct: 1201 GCLHDIQVHPIKNLHSSHSSGLMDKSSTIYSNSAESFLPGICKELIGSSLDFFGQSYDEE 1260
Query: 1261 RTIADSLINSFLKIYNGLFAISKAHEEQDEESQDNLFSSDRAIQSLTIQTACAFEQLVVL 1320
RTIADSLINSFLKIYNGLFAISKAHEEQDEESQDNLFSSDRAIQSLTIQTACAFEQLVVL
Sbjct: 1261 RTIADSLINSFLKIYNGLFAISKAHEEQDEESQDNLFSSDRAIQSLTIQTACAFEQLVVL 1320
Query: 1321 MKHWLSDLLPCTNIARLEDELRQEVKKLGGYLQLFLQGCCLDISSMIKEAQKNAIQIVQQ 1380
MKHWLSDLLPCTNIARLEDELRQEVKKLGGYLQLFLQGCCLDISSMIKEAQKNAIQIVQQ
Sbjct: 1321 MKHWLSDLLPCTNIARLEDELRQEVKKLGGYLQLFLQGCCLDISSMIKEAQKNAIQIVQQ 1380
Query: 1381 AVKYVGQLAVLKGSKLHFLENGNNKAASVQEEFMDAVCDGVGLGMKILLDSGLEKAKELQ 1440
AVKYVGQLAVLKGSKLHFLENGNNKAASVQEEFMDAVCDGVGLGMKILLDSGLEKAKELQ
Sbjct: 1381 AVKYVGQLAVLKGSKLHFLENGNNKAASVQEEFMDAVCDGVGLGMKILLDSGLEKAKELQ 1440
Query: 1441 HELFRQCTKNEVTKEMKTNAMGLIRSLENIFAESKIKSFRRQVQEENFEYQDFKRMVNRA 1500
HELFRQCTKNEVTKEMKTNAMGLIRSLENIFAESKIKSFRRQVQEENFEYQDFKRMVNRA
Sbjct: 1441 HELFRQCTKNEVTKEMKTNAMGLIRSLENIFAESKIKSFRRQVQEENFEYQDFKRMVNRA 1500
Query: 1501 PEFLKLKHCLEKAIEIIISALKGCHSDINLLQTCVESIRNLASDFYSDFSVPSTSVGSYE 1560
PEFLKLKHCLEKAIEIIISALKGCHSDINLLQTCVESIRNLASDFYSDFSVPSTSVGSYE
Sbjct: 1501 PEFLKLKHCLEKAIEIIISALKGCHSDINLLQTCVESIRNLASDFYSDFSVPSTSVGSYE 1560
Query: 1561 SRVTHIVHQELESLAKSLLFCFESEESPDLLKPWETYNQNTKEEHQQSKSSGIDGSKNKG 1620
SRVTHIVHQELESLAKSLLFCFESEESPDLLKPWETYNQNTKEEHQQSKSSGIDGSKNKG
Sbjct: 1561 SRVTHIVHQELESLAKSLLFCFESEESPDLLKPWETYNQNTKEEHQQSKSSGIDGSKNKG 1620
Query: 1621 VPKRVYELHGSSPAVSSEECTPSRIQWV 1648
VPKRVYELHGSSPAVSSEECTPSRIQWV
Sbjct: 1621 VPKRVYELHGSSPAVSSEECTPSRIQWV 1648
>gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]
Length = 1317
Score = 496 bits (1278), Expect = e-140
Identities = 307/760 (40%), Positives = 439/760 (57%), Gaps = 57/760 (7%)
Query: 357 SQVTVAVRVRPFTKREKIEKASQVVFMSGKEITVEH----------PDTKQVYNFIYDVS 406
+ V VAVRVRP +REK +A ++ M + T+ + ++ F YD S
Sbjct: 2 ASVKVAVRVRPMNRREKDLEAKFIIQMEKSKTTITNLKIPEGGTGDSGRERTKTFTYDFS 61
Query: 407 FWSFDECHPHYASQTTVYEKLAAPLLERAFEGFNTCLFAYGQTGSGKSYTMMGFSEEPGI 466
F+S D P Y SQ V++ L +++ AFEG+N C+FAYGQTGSGKSYTMMG S + G+
Sbjct: 62 FYSADTKSPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMGNSGDSGL 121
Query: 467 IPRFCEDLFSQVARK-QTQEVSYHIEMSFFEVYNEKIHDLLVCKDENGQRKQPLRVREHP 525
IPR CE LFS++ + E S+ E+S+ E+YNE++ DLL K + LRVREHP
Sbjct: 122 IPRICEGLFSRINETTRWDEASFRTEVSYLEIYNERVRDLLRRKSS---KTFNLRVREHP 178
Query: 526 VYGPYVEALSMNIVSSYADIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTKTEF 585
GPYVE LS ++V +Y D++ ++ GN R TAATGMND SSRSH++FT+ TQ K +
Sbjct: 179 KEGPYVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRSHAIFTIKFTQAKFD- 237
Query: 586 VEGEEHDHRITSRINLIDLAGSERCSTAHTNGDRLKEGVSINKSLLTLGKVISALSEQ-- 643
E S+I+L+DLAGSER G RLKEG +INKSL+TLG VISAL++
Sbjct: 238 ---SEMPCETVSKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLGNVISALADLSQ 294
Query: 644 ------ANQRSVFIPYRESVLTWLLKESLGGNSKTAMIATISPAASNIEETLSTLRYANQ 697
A ++ VF+PYR+SVLTWLLK+SLGGNSKT MIATISPA N ETLSTLRYAN+
Sbjct: 295 DAANTLAKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIATISPADVNYGETLSTLRYANR 354
Query: 698 ARLIVNIAKVNEDMNAKLIRELKAEIAKLKAAQRNSRNIDPERYRLCRQEITSLRMKLHQ 757
A+ I+N +NED N KLIREL+AEIA+LK I L S+ KL Q
Sbjct: 355 AKNIINKPTINEDANVKLIRELRAEIARLKTLLAQGNQI----ALLDSPTALSMEEKLQQ 410
Query: 758 QERDMAEMQRVWKEKFEQAEKRKLQETKELQKAGIMFQMDNHLPNLVNLNEDPQLSEMLL 817
E + E+ + W K+ + + ++T L+K GI +D+ LP+L+ +++D + ++L
Sbjct: 411 NEARVQELTKEWTNKWNETQNILKEQTLALRKEGIGVVLDSELPHLIGIDDDLLSTGIIL 470
Query: 818 YMIKEGTTTVGKYKPNSSHDIQLSGVLIADDHCTIKNFGGTVSIIPVGEAKTYVNGKHIL 877
Y +KEG T VG+ ++ DI L G+ + +HC +N GGTV++IP+ ++ VNG I+
Sbjct: 471 YHLKEGQTYVGRDDASTEQDIVLHGLDLESEHCIFENIGGTVTLIPLSGSQCSVNGVQIV 530
Query: 878 EITVLRHGDRVILGGDHYFRFNHPVEVQK--GKRPSGRDTPISEGPKDFEFAKNELLMA- 934
E T L G ++LG + FRFNHP E K KR SG + S D ++ L
Sbjct: 531 EATHLNQGAVILLGRTNMFRFNHPKEAAKLREKRKSGLLSSFSLSMTDLSKSRENLSAVM 590
Query: 935 -----------QRSQLE-AEIKEAQLKAKEEMMQGIQIAKEMAQQELSSQKAAYESKIKA 982
QR +LE E K ++ EE + + E QQE+ +Q+ E++I
Sbjct: 591 LYNPGLEFERQQREELEKLESKRKLIEEMEEKQKSDKAELERMQQEVETQRK--ETEIVQ 648
Query: 983 LEAELREESQRKKMQEINNQKAN--HKIEELEKAKQHLEQEIYVNKKRLEMET-LATKQA 1039
L+ +EES +++ I N+ + + E+ E+ + +QEI + KKR E ET L ++
Sbjct: 649 LQIRKQEESLKRRSFHIENKLKDLLAEKEKFEEERLREQQEIELQKKRQEEETFLRVQEE 708
Query: 1040 LEDHSIRHARILEALETEKQKIAKEVQILQQNRNNRDKTF 1079
L+ R+ E EK + + Q L Q + +D+ +
Sbjct: 709 LQ-------RLKELNNNEKAEKFQIFQELDQLQKEKDEQY 741
Score = 40.0 bits (92), Expect = 0.019
Identities = 90/438 (20%), Positives = 176/438 (40%), Gaps = 69/438 (15%)
Query: 686 EETLSTLRYANQARLIVNIAKVNEDMNAKLIRELKAEIAKLKAAQRNSRNIDPERYRLCR 745
EE+L + + +L +A+ + +L + + E+ K + + + E RL
Sbjct: 655 EESLKRRSFHIENKLKDLLAEKEKFEEERLREQQEIELQKKRQEEETFLRVQEELQRL-- 712
Query: 746 QEITSLRMKLHQQERDMAEMQRVWKEKFEQAEKRKLQETKELQKAGIMFQMDNHLPNLVN 805
+E+ + ++ + E+ ++ KEK EQ K +L++ + ++ + HL
Sbjct: 713 KELNNNEKA--EKFQIFQELDQLQKEKDEQYAKLELEKKRLEEQEKEQVMLVAHLEE--Q 768
Query: 806 LNEDPQLSEML--------------LYMIKEGTTTVGKYKPNSSHDIQLSGVLIADDHCT 851
L E ++ ++L L I+E V + + D G +
Sbjct: 769 LREKQEMIQLLRRGEVQWVEEEKRDLEGIRESLLRVKEARAGGDED----GEELEKAQLR 824
Query: 852 IKNFGGTVSIIPVGEAKTYVNGKHILEITVLRHGDRVILGGDHYFRFNHPVEVQKGKRPS 911
F + V K V K IL+ V + + + H E + ++
Sbjct: 825 FFEFKRRQLVKLVNLEKDLVQQKDILKKEVQEEQEIL-----ECLKCEHDKESRLLEKHD 879
Query: 912 GRDTPISEGPKDFE----------FAKNELLMAQRSQLEAEIKEAQLKAKEEMMQG---- 957
T ++E P+DFE + + +L ++ L ++E Q +A E + +G
Sbjct: 880 ESVTDVTEVPQDFEKIKPVEYRLQYKERQLQYLLQNHLPTLLEEKQ-RAFEILDRGPLSL 938
Query: 958 ----IQIAKEMAQQELS-SQKAAYESKIKALEAEL--------REESQRKKMQEINNQKA 1004
Q+ KEM ++E +Q A ++++ L+A +EE RKK +EI +
Sbjct: 939 DNTLYQVEKEMEEKEEQLAQYQANANQLQKLQATFEFTANIARQEEKVRKKEKEILESRE 998
Query: 1005 NHKIEELEKAKQHLEQEIYVNKKR----LEMETLATKQALEDHSIRHARIL--------E 1052
+ E LE+A LE+ ++ +E+E K A + R L E
Sbjct: 999 KQQREALERALARLERRHSALQRHSTLGMEIEEQRQKLASLNSGSREQSGLQASLEAEQE 1058
Query: 1053 ALETEKQKIAKEVQILQQ 1070
ALE +++++ E+Q L+Q
Sbjct: 1059 ALEKDQERLEYEIQQLKQ 1076
>gi|41393563 kinesin family member 1B isoform b [Homo sapiens]
Length = 1770
Score = 495 bits (1275), Expect = e-139
Identities = 328/888 (36%), Positives = 485/888 (54%), Gaps = 122/888 (13%)
Query: 354 VENSQVTVAVRVRPFTKREKIEKASQVVFMSGKEITVEHPDTKQVY--NFIYDVSFWSFD 411
+ + V VAVRVRPF RE +++ ++ M G ++ +P + +F +D S+WS
Sbjct: 1 MSGASVKVAVRVRPFNSRETSKESKCIIQMQGNSTSIINPKNPKEAPKSFSFDYSYWSHT 60
Query: 412 ECH-PHYASQTTVYEKLAAPLLERAFEGFNTCLFAYGQTGSGKSYTMMGFSEEP--GIIP 468
P +ASQ VY + +L AFEG+N C+FAYGQTG+GKSYTMMG EE GIIP
Sbjct: 61 SPEDPCFASQNRVYNDIGKEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGKQEESQAGIIP 120
Query: 469 RFCEDLFSQVARKQTQEVSYHIEMSFFEVYNEKIHDLLVCKDENGQRKQPLRVREHPVYG 528
+ CE+LF ++ +E+SY +E+S+ E+Y E++ DLL N + K LRVREHP+ G
Sbjct: 121 QLCEELFEKINDNCNEEMSYSVEVSYMEIYCERVRDLL-----NPKNKGNLRVREHPLLG 175
Query: 529 PYVEALSMNIVSSYADIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTKTEFVEG 588
PYVE LS V+SY DI ++ GNK R AAT MN+ SSRSH+VFT+V TQ K
Sbjct: 176 PYVEDLSKLAVTSYTDIADLMDAGNKARTVAATNMNETSSRSHAVFTIVFTQKK------ 229
Query: 589 EEHDHRIT------SRINLIDLAGSERCSTAHTNGDRLKEGVSINKSLLTLGKVISALSE 642
HD+ S+I+L+DLAGSER + G RLKEG +INKSL TLGKVISAL+E
Sbjct: 230 --HDNETNLSTEKVSKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAE 287
Query: 643 --QANQRSVFIPYRESVLTWLLKESLGGNSKTAMIATISPAASNIEETLSTLRYANQARL 700
+ +++ FIPYR+SVLTWLL+E+LGGNS+TAM+A +SPA N +ETLSTLRYA++A+
Sbjct: 288 VSKKKKKTDFIPYRDSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQ 347
Query: 701 IVNIAKVNEDMNAKLIRELKAEIAKLKAAQR------------NSRNIDPERYRLCRQ-- 746
I A +NED NAKL+RELK E+ +LK R S P L Q
Sbjct: 348 IKCNAVINEDPNAKLVRELKEEVTRLKDLLRAQGLGDIIDTSMGSLTSSPSSCSLSSQVG 407
Query: 747 --EITSLR-------------MKLHQQERDMAEMQRVWKEKFEQAEKRKLQETKELQKAG 791
+TS++ +L + E+ +AE+ W+EK + E +++ L + G
Sbjct: 408 LTSVTSIQERIMSTPGGEEAIERLKESEKIIAELNETWEEKLRKTEAIRMEREALLAEMG 467
Query: 792 IMFQMD---------NHLPNLVNLNEDPQLSEMLLYMIKEGTTTVGKYKPNSSHDIQLSG 842
+ + D P+LVNLNEDP +SE LLY IK+G T VG+ DI LSG
Sbjct: 468 VAIREDGGTLGVFSPKKTPHLVNLNEDPLMSECLLYYIKDGITRVGQADAERRQDIVLSG 527
Query: 843 VLIADDHCTIK----NFGGT-VSIIPVGEAKTYVNGKHILEITVLRHGDRVILGGDHYFR 897
I ++HC + N G V++ P ++TYVNGK + + LR G+R+I+G +H FR
Sbjct: 528 AHIKEEHCIFRSERSNSGEVIVTLEPCERSETYVNGKRVSQPVQLRSGNRIIMGKNHVFR 587
Query: 898 FNHP--VEVQKGKRPSGRDTPISEGPKDFEFAKNELLMAQ----RSQLEAEIKEAQLKAK 951
FNHP ++ K PS +TP P D+ FA+ ELL Q + ++E ++E ++ K
Sbjct: 588 FNHPEQARAEREKTPSA-ETP--SEPVDWTFAQRELLEKQGIDMKQEMEKRLQEMEILYK 644
Query: 952 EEMMQGIQIAKEMAQQELSSQKAAYESKIKALEAELREESQRKKMQEINNQKANHKIEEL 1011
+E KE A L Q+ YESK++AL+ ++ S + E ++ EE+
Sbjct: 645 KE--------KEEADLLLEQQRLDYESKLQALQKQVETRSLAAETTEEEEEE-----EEV 691
Query: 1012 EKAKQHLEQEIYVNKKRLEMETLATKQALEDHSIRHARILEALETE-KQKIAKEVQILQQ 1070
+ E + +K + + + L +++ + + A+ E K+K+ + +L
Sbjct: 692 PWTQHEFELAQWAFRKWKSHQFTSLRDLLWGNAV-YLKEANAISVELKKKVQFQFVLL-- 748
Query: 1071 NRNNRDKTFTVQTTWSSMKLSMMIQEANAISSKLKTYYVFGRHDISDKSSSDTSIRVRNL 1130
T +S + ++ E KT H+ + ++ V++L
Sbjct: 749 ----------TDTLYSPLPPELLPTEME------KT------HEDRPFPRTVVAVEVQDL 786
Query: 1131 KLGISTFWSLEKFESKLAAMKELYESNGSNRGEDAFCDPEDEWEPDIT 1178
K G + +WSLEK + +L M+E+Y+ R + +DE E +T
Sbjct: 787 KNGATHYWSLEKLKQRLDLMREMYD-----RAGEMASSAQDESETTVT 829
>gi|19924175 axonal transport of synaptic vesicles [Homo sapiens]
Length = 1690
Score = 480 bits (1236), Expect = e-135
Identities = 319/856 (37%), Positives = 465/856 (54%), Gaps = 99/856 (11%)
Query: 357 SQVTVAVRVRPFTKREKIEKASQVVFMSGKEITVEHPDTKQVY--NFIYDVSFWSFDECH 414
+ V VAVRVRPF RE + ++ MSG T+ +P + +F +D S+WS
Sbjct: 4 ASVKVAVRVRPFNSREMSRDSKCIIQMSGSTTTIVNPKQPKETPKSFSFDYSYWSHTSPE 63
Query: 415 P-HYASQTTVYEKLAAPLLERAFEGFNTCLFAYGQTGSGKSYTMMGFSE--EPGIIPRFC 471
+YASQ VY + +L+ AFEG+N C+FAYGQTG+GKSYTMMG E + GIIP+ C
Sbjct: 64 DINYASQKQVYRDIGEEMLQHAFEGYNVCIFAYGQTGAGKSYTMMGKQEKDQQGIIPQLC 123
Query: 472 EDLFSQVARKQTQEVSYHIEMSFFEVYNEKIHDLLVCKDENGQRKQPLRVREHPVYGPYV 531
EDLFS++ +SY +E+S+ E+Y E++ DLL N + K LRVREHP+ GPYV
Sbjct: 124 EDLFSRINDTTNDNMSYSVEVSYMEIYCERVRDLL-----NPKNKGNLRVREHPLLGPYV 178
Query: 532 EALSMNIVSSYADIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTKTEFVEGEEH 591
E LS V+SY DIQ ++ GNK R AAT MN+ SSRSH+VF ++ TQ + + E
Sbjct: 179 EDLSKLAVTSYNDIQDLMDSGNKARTVAATNMNETSSRSHAVFNIIFTQKRHD-AETNIT 237
Query: 592 DHRITSRINLIDLAGSERCSTAHTNGDRLKEGVSINKSLLTLGKVISALSE--------Q 643
++ S+I+L+DLAGSER + G RLKEG +INKSL TLGKVISAL+E +
Sbjct: 238 TEKV-SKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEMDSGPNKNK 296
Query: 644 ANQRSVFIPYRESVLTWLLKESLGGNSKTAMIATISPAASNIEETLSTLRYANQARLIVN 703
+++ FIPYR+SVLTWLL+E+LGGNS+TAM+A +SPA N +ETLSTLRYA++A+ I
Sbjct: 297 KKKKTDFIPYRDSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQIRC 356
Query: 704 IAKVNEDMNAKLIRELKAEIAKLK---AAQRNSRNIDPERYRLCRQEITSLRM------- 753
A +NED N KLIRELK E+ +L+ AQ D + +SL
Sbjct: 357 NAVINEDPNNKLIRELKDEVTRLRDLLYAQGLGDITDMTNALVGMSPSSSLSALSSRAAS 416
Query: 754 -------------------KLHQQERDMAEMQRVWKEKFEQAEKRKLQETKELQKAGIMF 794
+L + E+ +AE+ W+EK + E +++ L + G+
Sbjct: 417 VSSLHERILFAPGSEEAIERLKETEKIIAELNETWEEKLRRTEAIRMEREALLAEMGVAM 476
Query: 795 QMD---------NHLPNLVNLNEDPQLSEMLLYMIKEGTTTVGKYKPNSSHDIQLSGVLI 845
+ D P+LVNLNEDP +SE LLY IK+G T VG+ DI LSG I
Sbjct: 477 REDGGTLGVFSPKKTPHLVNLNEDPLMSECLLYYIKDGITRVGREDGERRQDIVLSGHFI 536
Query: 846 ADDHCTIK--NFGGTVSII---PVGEAKTYVNGKHILEITVLRHGDRVILGGDHYFRFNH 900
++HC + + GG+ +++ P A TYVNGK + E ++LR G+R+I+G H FRFNH
Sbjct: 537 KEEHCVFRSDSRGGSEAVVTLEPCEGADTYVNGKKVTEPSILRSGNRIIMGKSHVFRFNH 596
Query: 901 PVEV-QKGKRPSGRDTPISEGPKDFEFAKNELLMAQRSQLEAEIKEAQLKAKEEMMQGIQ 959
P + Q+ +R +TP P D+ FA+ ELL Q ++ E+++ +E+ +
Sbjct: 597 PEQARQERERTPCAETPAE--PVDWAFAQRELLEKQGIDMKQEMEQ----RLQELEDQYR 650
Query: 960 IAKEMAQQELSSQKAAYESKIKALEAELREESQRKKMQEINNQKANHKIEELEKAKQHLE 1019
+E A L Q+ YESK++AL+ K+M + N + EE E Q E
Sbjct: 651 REREEATYLLEQQRLDYESKLEALQ---------KQMDSRYYPEVNEEEEEPEDEVQWTE 701
Query: 1020 QEIYVNKKRLEMETLATKQALEDHSIRHARILEALETEKQKIAKEVQILQQNRNNRDKTF 1079
+E + +L D +A L+ ++ K+VQ
Sbjct: 702 RECELALWAFRKWKWYQFTSLRDLLWGNAIFLKEANAISVELKKKVQF--------QFVL 753
Query: 1080 TVQTTWSSMKLSMMIQEANAISSKLKTYYVFGRHDISDKSSSDTSIRVRNLKLGISTFWS 1139
T +S + ++ EA +K + F R + ++ V++ K G + +W+
Sbjct: 754 LTDTLYSPLPPDLLPPEA----AKDRETRPFPR--------TIVAVEVQDQKNGATHYWT 801
Query: 1140 LEKFESKLAAMKELYE 1155
LEK +L M+E+Y+
Sbjct: 802 LEKLRQRLDLMREMYD 817
>gi|46852172 kinesin family member 13B [Homo sapiens]
Length = 1826
Score = 469 bits (1208), Expect = e-132
Identities = 297/821 (36%), Positives = 463/821 (56%), Gaps = 76/821 (9%)
Query: 356 NSQVTVAVRVRPFTKREKIEKASQVVFMSGKEITVEHPDTK--------QVYNFIYDVSF 407
+S+V VAVR+RP +RE VV + ++ + +T Q F YD F
Sbjct: 3 DSKVKVAVRIRPMNRRETDLHTKCVVDVDANKVILNPVNTNLSKGDARGQPKVFAYDHCF 62
Query: 408 WSFDEC-HPHYASQTTVYEKLAAPLLERAFEGFNTCLFAYGQTGSGKSYTMMGFSEEPGI 466
WS DE YA Q V++ L +L+ AF+G+N C+FAYGQTGSGKSYTMMG +++PG+
Sbjct: 63 WSMDESVKEKYAGQDIVFKCLGENILQNAFDGYNACIFAYGQTGSGKSYTMMGTADQPGL 122
Query: 467 IPRFCEDLFSQVARKQTQEVSYHIEMSFFEVYNEKIHDLLVCKDENGQRKQPLRVREHPV 526
IPR C LF + +++ +E S+ +E+S+ E+YNEK+ DLL D G R Q L+VREH V
Sbjct: 123 IPRLCSGLFERTQKEENEEQSFKVEVSYMEIYNEKVRDLL---DPKGSR-QTLKVREHSV 178
Query: 527 YGPYVEALSMNIVSSYADIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTKTEFV 586
GPYV+ LS V+SY DI+S + GNK R AAT MN++SSRSH+VF + +T T +
Sbjct: 179 LGPYVDGLSKLAVTSYKDIESLMSEGNKSRTVAATNMNEESSRSHAVFKITLTHTLYDVK 238
Query: 587 EGEEHDHRITSRINLIDLAGSERCSTAHTNGDRLKEGVSINKSLLTLGKVISALSEQA-- 644
G + +++L+DLAGSER + GDRLKEG +INKSL TLG VISAL++Q+
Sbjct: 239 SGTSGEK--VGKLSLVDLAGSERATKTGAAGDRLKEGSNINKSLTTLGLVISALADQSAG 296
Query: 645 NQRSVFIPYRESVLTWLLKESLGGNSKTAMIATISPAASNIEETLSTLRYANQARLIVNI 704
++ F+PYR+SVLTWLLK+SLGGNSKTAM+AT+SPAA N +ETLSTLRYA++A+ IVN
Sbjct: 297 KNKNKFVPYRDSVLTWLLKDSLGGNSKTAMVATVSPAADNYDETLSTLRYADRAKHIVNH 356
Query: 705 AKVNEDMNAKLIRELKAEIAKLKAAQRNSRNI-DPERYRLCRQEITSLRMKLHQQERDMA 763
A VNED NA++IR+L+ E+ KL+ + + PE L+ +L + E+ +
Sbjct: 357 AVVNEDPNARIIRDLREEVEKLREQLTKAEAMKSPE-----------LKDRLEESEKLIQ 405
Query: 764 EMQRVWKEKFEQAEKRKLQETKELQKAGIMFQ-----MDNHLPNLVNLNEDPQLSEMLLY 818
EM W+EK + E+ + K+L+ GI Q + + LVNLN DP L+E+L+Y
Sbjct: 406 EMTVTWEEKLRKTEEIAQERQKQLESLGISLQSSGIKVGDDKCFLVNLNADPALNELLVY 465
Query: 819 MIKEGTTTVGKYKPNSSHDIQLSGVLIADDHCTIK-NFGGTVSIIPVGEAKTYVNGKHIL 877
+KE T +G +S DIQL G+ I +HC I G V + P +T+VNG +
Sbjct: 466 YLKE-HTLIGS---ANSQDIQLCGMGILPEHCIIDITSEGQVMLTPQKNTRTFVNGSSVS 521
Query: 878 EITVLRHGDRVILGGDHYFRFNHPVEVQKGKRPSGRDTPISEGPKDFEFAKNELLMAQRS 937
L HGDR++ G +H+FR N P + +K +R P + ++
Sbjct: 522 SPIQLHHGDRILWGNNHFFRLNLPKKKKKAEREDEDQDP-----------------SMKN 564
Query: 938 QLEAEIKEAQLKAKEEMMQGIQIAKEMAQQELSSQKAAYESKIKALEAELREESQRKKMQ 997
+ +E + + E+ + E AQ E++ + ++++ L ++ + +K
Sbjct: 565 ENSSEQLDVDGDSSSEVSSEVNFNYEYAQMEVTMKALGSNDPMQSILNSLEQQHEEEKRS 624
Query: 998 EINNQKANHKIEELEKAKQHL--EQEIYVNKKRLEMETLATKQALEDHS-IRHARILEAL 1054
+ Q+ ++ ELE+ ++ L E++ + R + + +Q L + R A + +L
Sbjct: 625 ALERQRLMYE-HELEQLRRRLSPEKQNCRSMDRFSFHSPSAQQRLRQWAEEREATLNNSL 683
Query: 1055 ETEKQKIAKEVQILQQNRNNRDKTFTVQTTWSSMKLSMMIQEANAISSKLKTYYVFGRHD 1114
+++I K +L + N + +T + K+++ I ++ +++ + +
Sbjct: 684 MRLREQIVK-ANLLVREANYIAEELDKRTEY---KVTLQIPASSLDANRKRGSLL----- 734
Query: 1115 ISDKSSSDTSIRVRNLKLGISTFWSLEKFESKLAAMKELYE 1155
S+ +I+VR G WSLEK +++L M++LY+
Sbjct: 735 ------SEPAIQVRRKGKG-KQIWSLEKLDNRLLDMRDLYQ 768
>gi|157738629 kinesin family member 13A isoform d [Homo sapiens]
Length = 1749
Score = 468 bits (1204), Expect = e-131
Identities = 313/831 (37%), Positives = 465/831 (55%), Gaps = 100/831 (12%)
Query: 354 VENSQVTVAVRVRPFTKREKIEKASQVVFMSGKEITVEHP---DTKQVYN-----FIYDV 405
+ +++V VAVRVRP +RE VV M G + TV HP +TKQ F +D
Sbjct: 1 MSDTKVKVAVRVRPMNRRELELNTKCVVEMEGNQ-TVLHPPPSNTKQGERKPPKVFAFDY 59
Query: 406 SFWSFDECHP-HYASQTTVYEKLAAPLLERAFEGFNTCLFAYGQTGSGKSYTMMGFSEEP 464
FWS DE + YA Q V++ L +LE+AF+G+N C+FAYGQTGSGKS++MMG +E+
Sbjct: 60 CFWSMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMGHAEQL 119
Query: 465 GIIPRFCEDLFSQVARKQTQEVSYHIEMSFFEVYNEKIHDLLVCKDENGQRKQPLRVREH 524
G+IPR C LF +++ +Q + ++ +E+S+ E+YNEK+ DLL D G R Q L+VREH
Sbjct: 120 GLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLL---DPKGSR-QSLKVREH 175
Query: 525 PVYGPYVEALSMNIVSSYADIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTKTE 584
V GPYV+ LS V+S+ DI+S + GNK R AAT MN++SSRSH+VF +++TQT +
Sbjct: 176 KVLGPYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQTLYD 235
Query: 585 FVEGEEHDHRITSRINLIDLAGSERCSTAHTNGDRLKEGVSINKSLLTLGKVISALSEQA 644
G + S+++L+DLAGSER S G+RLKEG +INKSL TLG VIS+L++QA
Sbjct: 236 LQSGNSGEK--VSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLADQA 293
Query: 645 --NQRSVFIPYRESVLTWLLKESLGGNSKTAMIATISPAASNIEETLSTLRYANQARLIV 702
+S F+PYR+SVLTWLLK++LGGNS+T+MIATISPAA N EETLSTLRYA++A+ IV
Sbjct: 294 AGKGKSKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRAKRIV 353
Query: 703 NIAKVNEDMNAKLIRELKAEIAKLKAAQRNSRNIDPERYRLCRQEITSLRMKLHQQERDM 762
N A VNED NAK+IREL+ E+ KL+ + + L+ KL + E+ +
Sbjct: 354 NHAVVNEDPNAKVIRELREEVEKLREQLSQAE----------AMKAPELKEKLEESEKLI 403
Query: 763 AEMQRVWKEKFEQAEKRKLQETKELQKAGIMFQMD-----NHLPNLVNLNEDPQLSEMLL 817
E+ W+EK + E+ + ++L+ GI +M + LVNLN DP L+E+L+
Sbjct: 404 KELTVTWEEKLRKTEEIAQERQRQLESMGISLEMSGIKVGDDKCYLVNLNADPALNELLV 463
Query: 818 YMIKEGTTTVGKYKPNSSHDIQLSGVLIADDHCTIK-NFGGTVSIIPVGEAKTYVNGKHI 876
Y +K+ T + ++S DIQL G+ I HC I G V++ P A++ VNG +
Sbjct: 464 YYLKDHT----RVGADTSQDIQLFGIGIQPQHCEIDIASDGDVTLTPKENARSCVNGTLV 519
Query: 877 LEITVLRHGDRVILGGDHYFRFNHPVEVQKGKRPSGRDTPISEGPKDFEFAKNELLMAQR 936
T L HGDR++ G +H+FR N P K KR + KDFE
Sbjct: 520 CSTTQLWHGDRILWGNNHFFRINLP----KRKR--------RDWLKDFE----------- 556
Query: 937 SQLEAEIKEAQLKAKEEMMQGIQIAKEMAQQELSSQKAAYESKIKALEAELREESQRKKM 996
E E L A E E AQ E+ + ++ + L ++ +K
Sbjct: 557 --KETGPPEHDLDAASEASSEPDYNYEFAQMEVIMKTLNSNDPVQNVVQVLEKQYLEEKR 614
Query: 997 QEINNQKANHKIEELEKAKQHLEQEIYVNKKRLEMETLATKQALEDHSIRHARILEALET 1056
+ Q+ ++ ELE+ +Q L + + S R+ + +T
Sbjct: 615 SALEEQRLMYE-RELEQLRQQLSPD------------------RQPQSSGPDRLAYSSQT 655
Query: 1057 EKQKIAKEVQILQQNRNNRDKTFTVQTTWSSMKLSMMIQEANAIS---SKLKTYYVFGRH 1113
+QK+ + + R+ + + +K + +++EAN ++ SKL Y V +
Sbjct: 656 AQQKVTQ----WAEERDELFRQSLAKLREQLVKANTLVREANFLAEEMSKLTDYQVTLQI 711
Query: 1114 DISDKSS--------SDTSIRVRNLKLGIST-FWSLEKFESKLAAMKELYE 1155
++ S+ S+ +I+VR + G ST W++EK E+KL M++LY+
Sbjct: 712 PAANLSANRKRGAIVSEPAIQVR--RKGKSTQVWTIEKLENKLIDMRDLYQ 760
>gi|157738627 kinesin family member 13A isoform c [Homo sapiens]
Length = 1757
Score = 468 bits (1204), Expect = e-131
Identities = 313/831 (37%), Positives = 465/831 (55%), Gaps = 100/831 (12%)
Query: 354 VENSQVTVAVRVRPFTKREKIEKASQVVFMSGKEITVEHP---DTKQVYN-----FIYDV 405
+ +++V VAVRVRP +RE VV M G + TV HP +TKQ F +D
Sbjct: 1 MSDTKVKVAVRVRPMNRRELELNTKCVVEMEGNQ-TVLHPPPSNTKQGERKPPKVFAFDY 59
Query: 406 SFWSFDECHP-HYASQTTVYEKLAAPLLERAFEGFNTCLFAYGQTGSGKSYTMMGFSEEP 464
FWS DE + YA Q V++ L +LE+AF+G+N C+FAYGQTGSGKS++MMG +E+
Sbjct: 60 CFWSMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMGHAEQL 119
Query: 465 GIIPRFCEDLFSQVARKQTQEVSYHIEMSFFEVYNEKIHDLLVCKDENGQRKQPLRVREH 524
G+IPR C LF +++ +Q + ++ +E+S+ E+YNEK+ DLL D G R Q L+VREH
Sbjct: 120 GLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLL---DPKGSR-QSLKVREH 175
Query: 525 PVYGPYVEALSMNIVSSYADIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTKTE 584
V GPYV+ LS V+S+ DI+S + GNK R AAT MN++SSRSH+VF +++TQT +
Sbjct: 176 KVLGPYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQTLYD 235
Query: 585 FVEGEEHDHRITSRINLIDLAGSERCSTAHTNGDRLKEGVSINKSLLTLGKVISALSEQA 644
G + S+++L+DLAGSER S G+RLKEG +INKSL TLG VIS+L++QA
Sbjct: 236 LQSGNSGEK--VSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLADQA 293
Query: 645 --NQRSVFIPYRESVLTWLLKESLGGNSKTAMIATISPAASNIEETLSTLRYANQARLIV 702
+S F+PYR+SVLTWLLK++LGGNS+T+MIATISPAA N EETLSTLRYA++A+ IV
Sbjct: 294 AGKGKSKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRAKRIV 353
Query: 703 NIAKVNEDMNAKLIRELKAEIAKLKAAQRNSRNIDPERYRLCRQEITSLRMKLHQQERDM 762
N A VNED NAK+IREL+ E+ KL+ + + L+ KL + E+ +
Sbjct: 354 NHAVVNEDPNAKVIRELREEVEKLREQLSQAE----------AMKAPELKEKLEESEKLI 403
Query: 763 AEMQRVWKEKFEQAEKRKLQETKELQKAGIMFQMD-----NHLPNLVNLNEDPQLSEMLL 817
E+ W+EK + E+ + ++L+ GI +M + LVNLN DP L+E+L+
Sbjct: 404 KELTVTWEEKLRKTEEIAQERQRQLESMGISLEMSGIKVGDDKCYLVNLNADPALNELLV 463
Query: 818 YMIKEGTTTVGKYKPNSSHDIQLSGVLIADDHCTIK-NFGGTVSIIPVGEAKTYVNGKHI 876
Y +K+ T + ++S DIQL G+ I HC I G V++ P A++ VNG +
Sbjct: 464 YYLKDHT----RVGADTSQDIQLFGIGIQPQHCEIDIASDGDVTLTPKENARSCVNGTLV 519
Query: 877 LEITVLRHGDRVILGGDHYFRFNHPVEVQKGKRPSGRDTPISEGPKDFEFAKNELLMAQR 936
T L HGDR++ G +H+FR N P K KR + KDFE
Sbjct: 520 CSTTQLWHGDRILWGNNHFFRINLP----KRKR--------RDWLKDFE----------- 556
Query: 937 SQLEAEIKEAQLKAKEEMMQGIQIAKEMAQQELSSQKAAYESKIKALEAELREESQRKKM 996
E E L A E E AQ E+ + ++ + L ++ +K
Sbjct: 557 --KETGPPEHDLDAASEASSEPDYNYEFAQMEVIMKTLNSNDPVQNVVQVLEKQYLEEKR 614
Query: 997 QEINNQKANHKIEELEKAKQHLEQEIYVNKKRLEMETLATKQALEDHSIRHARILEALET 1056
+ Q+ ++ ELE+ +Q L + + S R+ + +T
Sbjct: 615 SALEEQRLMYE-RELEQLRQQLSPD------------------RQPQSSGPDRLAYSSQT 655
Query: 1057 EKQKIAKEVQILQQNRNNRDKTFTVQTTWSSMKLSMMIQEANAIS---SKLKTYYVFGRH 1113
+QK+ + + R+ + + +K + +++EAN ++ SKL Y V +
Sbjct: 656 AQQKVTQ----WAEERDELFRQSLAKLREQLVKANTLVREANFLAEEMSKLTDYQVTLQI 711
Query: 1114 DISDKSS--------SDTSIRVRNLKLGIST-FWSLEKFESKLAAMKELYE 1155
++ S+ S+ +I+VR + G ST W++EK E+KL M++LY+
Sbjct: 712 PAANLSANRKRGAIVSEPAIQVR--RKGKSTQVWTIEKLENKLIDMRDLYQ 760
>gi|157738625 kinesin family member 13A isoform b [Homo sapiens]
Length = 1770
Score = 468 bits (1204), Expect = e-131
Identities = 313/831 (37%), Positives = 465/831 (55%), Gaps = 100/831 (12%)
Query: 354 VENSQVTVAVRVRPFTKREKIEKASQVVFMSGKEITVEHP---DTKQVYN-----FIYDV 405
+ +++V VAVRVRP +RE VV M G + TV HP +TKQ F +D
Sbjct: 1 MSDTKVKVAVRVRPMNRRELELNTKCVVEMEGNQ-TVLHPPPSNTKQGERKPPKVFAFDY 59
Query: 406 SFWSFDECHP-HYASQTTVYEKLAAPLLERAFEGFNTCLFAYGQTGSGKSYTMMGFSEEP 464
FWS DE + YA Q V++ L +LE+AF+G+N C+FAYGQTGSGKS++MMG +E+
Sbjct: 60 CFWSMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMGHAEQL 119
Query: 465 GIIPRFCEDLFSQVARKQTQEVSYHIEMSFFEVYNEKIHDLLVCKDENGQRKQPLRVREH 524
G+IPR C LF +++ +Q + ++ +E+S+ E+YNEK+ DLL D G R Q L+VREH
Sbjct: 120 GLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLL---DPKGSR-QSLKVREH 175
Query: 525 PVYGPYVEALSMNIVSSYADIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTKTE 584
V GPYV+ LS V+S+ DI+S + GNK R AAT MN++SSRSH+VF +++TQT +
Sbjct: 176 KVLGPYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQTLYD 235
Query: 585 FVEGEEHDHRITSRINLIDLAGSERCSTAHTNGDRLKEGVSINKSLLTLGKVISALSEQA 644
G + S+++L+DLAGSER S G+RLKEG +INKSL TLG VIS+L++QA
Sbjct: 236 LQSGNSGEK--VSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLADQA 293
Query: 645 --NQRSVFIPYRESVLTWLLKESLGGNSKTAMIATISPAASNIEETLSTLRYANQARLIV 702
+S F+PYR+SVLTWLLK++LGGNS+T+MIATISPAA N EETLSTLRYA++A+ IV
Sbjct: 294 AGKGKSKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRAKRIV 353
Query: 703 NIAKVNEDMNAKLIRELKAEIAKLKAAQRNSRNIDPERYRLCRQEITSLRMKLHQQERDM 762
N A VNED NAK+IREL+ E+ KL+ + + L+ KL + E+ +
Sbjct: 354 NHAVVNEDPNAKVIRELREEVEKLREQLSQAE----------AMKAPELKEKLEESEKLI 403
Query: 763 AEMQRVWKEKFEQAEKRKLQETKELQKAGIMFQMD-----NHLPNLVNLNEDPQLSEMLL 817
E+ W+EK + E+ + ++L+ GI +M + LVNLN DP L+E+L+
Sbjct: 404 KELTVTWEEKLRKTEEIAQERQRQLESMGISLEMSGIKVGDDKCYLVNLNADPALNELLV 463
Query: 818 YMIKEGTTTVGKYKPNSSHDIQLSGVLIADDHCTIK-NFGGTVSIIPVGEAKTYVNGKHI 876
Y +K+ T + ++S DIQL G+ I HC I G V++ P A++ VNG +
Sbjct: 464 YYLKDHT----RVGADTSQDIQLFGIGIQPQHCEIDIASDGDVTLTPKENARSCVNGTLV 519
Query: 877 LEITVLRHGDRVILGGDHYFRFNHPVEVQKGKRPSGRDTPISEGPKDFEFAKNELLMAQR 936
T L HGDR++ G +H+FR N P K KR + KDFE
Sbjct: 520 CSTTQLWHGDRILWGNNHFFRINLP----KRKR--------RDWLKDFE----------- 556
Query: 937 SQLEAEIKEAQLKAKEEMMQGIQIAKEMAQQELSSQKAAYESKIKALEAELREESQRKKM 996
E E L A E E AQ E+ + ++ + L ++ +K
Sbjct: 557 --KETGPPEHDLDAASEASSEPDYNYEFAQMEVIMKTLNSNDPVQNVVQVLEKQYLEEKR 614
Query: 997 QEINNQKANHKIEELEKAKQHLEQEIYVNKKRLEMETLATKQALEDHSIRHARILEALET 1056
+ Q+ ++ ELE+ +Q L + + S R+ + +T
Sbjct: 615 SALEEQRLMYE-RELEQLRQQLSPD------------------RQPQSSGPDRLAYSSQT 655
Query: 1057 EKQKIAKEVQILQQNRNNRDKTFTVQTTWSSMKLSMMIQEANAIS---SKLKTYYVFGRH 1113
+QK+ + + R+ + + +K + +++EAN ++ SKL Y V +
Sbjct: 656 AQQKVTQ----WAEERDELFRQSLAKLREQLVKANTLVREANFLAEEMSKLTDYQVTLQI 711
Query: 1114 DISDKSS--------SDTSIRVRNLKLGIST-FWSLEKFESKLAAMKELYE 1155
++ S+ S+ +I+VR + G ST W++EK E+KL M++LY+
Sbjct: 712 PAANLSANRKRGAIVSEPAIQVR--RKGKSTQVWTIEKLENKLIDMRDLYQ 760
>gi|157738621 kinesin family member 13A isoform a [Homo sapiens]
Length = 1805
Score = 468 bits (1204), Expect = e-131
Identities = 313/831 (37%), Positives = 465/831 (55%), Gaps = 100/831 (12%)
Query: 354 VENSQVTVAVRVRPFTKREKIEKASQVVFMSGKEITVEHP---DTKQVYN-----FIYDV 405
+ +++V VAVRVRP +RE VV M G + TV HP +TKQ F +D
Sbjct: 1 MSDTKVKVAVRVRPMNRRELELNTKCVVEMEGNQ-TVLHPPPSNTKQGERKPPKVFAFDY 59
Query: 406 SFWSFDECHP-HYASQTTVYEKLAAPLLERAFEGFNTCLFAYGQTGSGKSYTMMGFSEEP 464
FWS DE + YA Q V++ L +LE+AF+G+N C+FAYGQTGSGKS++MMG +E+
Sbjct: 60 CFWSMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMGHAEQL 119
Query: 465 GIIPRFCEDLFSQVARKQTQEVSYHIEMSFFEVYNEKIHDLLVCKDENGQRKQPLRVREH 524
G+IPR C LF +++ +Q + ++ +E+S+ E+YNEK+ DLL D G R Q L+VREH
Sbjct: 120 GLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLL---DPKGSR-QSLKVREH 175
Query: 525 PVYGPYVEALSMNIVSSYADIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTKTE 584
V GPYV+ LS V+S+ DI+S + GNK R AAT MN++SSRSH+VF +++TQT +
Sbjct: 176 KVLGPYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQTLYD 235
Query: 585 FVEGEEHDHRITSRINLIDLAGSERCSTAHTNGDRLKEGVSINKSLLTLGKVISALSEQA 644
G + S+++L+DLAGSER S G+RLKEG +INKSL TLG VIS+L++QA
Sbjct: 236 LQSGNSGEK--VSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLADQA 293
Query: 645 --NQRSVFIPYRESVLTWLLKESLGGNSKTAMIATISPAASNIEETLSTLRYANQARLIV 702
+S F+PYR+SVLTWLLK++LGGNS+T+MIATISPAA N EETLSTLRYA++A+ IV
Sbjct: 294 AGKGKSKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRAKRIV 353
Query: 703 NIAKVNEDMNAKLIRELKAEIAKLKAAQRNSRNIDPERYRLCRQEITSLRMKLHQQERDM 762
N A VNED NAK+IREL+ E+ KL+ + + L+ KL + E+ +
Sbjct: 354 NHAVVNEDPNAKVIRELREEVEKLREQLSQAE----------AMKAPELKEKLEESEKLI 403
Query: 763 AEMQRVWKEKFEQAEKRKLQETKELQKAGIMFQMD-----NHLPNLVNLNEDPQLSEMLL 817
E+ W+EK + E+ + ++L+ GI +M + LVNLN DP L+E+L+
Sbjct: 404 KELTVTWEEKLRKTEEIAQERQRQLESMGISLEMSGIKVGDDKCYLVNLNADPALNELLV 463
Query: 818 YMIKEGTTTVGKYKPNSSHDIQLSGVLIADDHCTIK-NFGGTVSIIPVGEAKTYVNGKHI 876
Y +K+ T + ++S DIQL G+ I HC I G V++ P A++ VNG +
Sbjct: 464 YYLKDHT----RVGADTSQDIQLFGIGIQPQHCEIDIASDGDVTLTPKENARSCVNGTLV 519
Query: 877 LEITVLRHGDRVILGGDHYFRFNHPVEVQKGKRPSGRDTPISEGPKDFEFAKNELLMAQR 936
T L HGDR++ G +H+FR N P K KR + KDFE
Sbjct: 520 CSTTQLWHGDRILWGNNHFFRINLP----KRKR--------RDWLKDFE----------- 556
Query: 937 SQLEAEIKEAQLKAKEEMMQGIQIAKEMAQQELSSQKAAYESKIKALEAELREESQRKKM 996
E E L A E E AQ E+ + ++ + L ++ +K
Sbjct: 557 --KETGPPEHDLDAASEASSEPDYNYEFAQMEVIMKTLNSNDPVQNVVQVLEKQYLEEKR 614
Query: 997 QEINNQKANHKIEELEKAKQHLEQEIYVNKKRLEMETLATKQALEDHSIRHARILEALET 1056
+ Q+ ++ ELE+ +Q L + + S R+ + +T
Sbjct: 615 SALEEQRLMYE-RELEQLRQQLSPD------------------RQPQSSGPDRLAYSSQT 655
Query: 1057 EKQKIAKEVQILQQNRNNRDKTFTVQTTWSSMKLSMMIQEANAIS---SKLKTYYVFGRH 1113
+QK+ + + R+ + + +K + +++EAN ++ SKL Y V +
Sbjct: 656 AQQKVTQ----WAEERDELFRQSLAKLREQLVKANTLVREANFLAEEMSKLTDYQVTLQI 711
Query: 1114 DISDKSS--------SDTSIRVRNLKLGIST-FWSLEKFESKLAAMKELYE 1155
++ S+ S+ +I+VR + G ST W++EK E+KL M++LY+
Sbjct: 712 PAANLSANRKRGAIVSEPAIQVR--RKGKSTQVWTIEKLENKLIDMRDLYQ 760
>gi|41393559 kinesin family member 1B isoform alpha [Homo sapiens]
Length = 1153
Score = 468 bits (1204), Expect = e-131
Identities = 295/716 (41%), Positives = 412/716 (57%), Gaps = 90/716 (12%)
Query: 354 VENSQVTVAVRVRPFTKREKIEKASQVVFMSGKEITVEHPDTKQVY--NFIYDVSFWSFD 411
+ + V VAVRVRPF RE +++ ++ M G ++ +P + +F +D S+WS
Sbjct: 1 MSGASVKVAVRVRPFNSRETSKESKCIIQMQGNSTSIINPKNPKEAPKSFSFDYSYWSHT 60
Query: 412 ECH-PHYASQTTVYEKLAAPLLERAFEGFNTCLFAYGQTGSGKSYTMMGFSEEP--GIIP 468
P +ASQ VY + +L AFEG+N C+FAYGQTG+GKSYTMMG EE GIIP
Sbjct: 61 SPEDPCFASQNRVYNDIGKEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGKQEESQAGIIP 120
Query: 469 RFCEDLFSQVARKQTQEVSYHIEMSFFEVYNEKIHDLLVCKDENGQRKQPLRVREHPVYG 528
+ CE+LF ++ +E+SY +E+S+ E+Y E++ DLL N + K LRVREHP+ G
Sbjct: 121 QLCEELFEKINDNCNEEMSYSVEVSYMEIYCERVRDLL-----NPKNKGNLRVREHPLLG 175
Query: 529 PYVEALSMNIVSSYADIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTKTEFVEG 588
PYVE LS V+SY DI ++ GNK R AAT MN+ SSRSH+VFT+V TQ K
Sbjct: 176 PYVEDLSKLAVTSYTDIADLMDAGNKARTVAATNMNETSSRSHAVFTIVFTQKK------ 229
Query: 589 EEHDHRIT------SRINLIDLAGSERCSTAHTNGDRLKEGVSINKSLLTLGKVISALSE 642
HD+ S+I+L+DLAGSER + G RLKEG +INKSL TLGKVISAL+E
Sbjct: 230 --HDNETNLSTEKVSKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAE 287
Query: 643 --QANQRSVFIPYRESVLTWLLKESLGGNSKTAMIATISPAASNIEETLSTLRYANQARL 700
+ +++ FIPYR+SVLTWLL+E+LGGNS+TAM+A +SPA N +ETLSTLRYA++A+
Sbjct: 288 VSKKKKKTDFIPYRDSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQ 347
Query: 701 IVNIAKVNEDMNAKLIRELKAEIAKLKAAQR------------NSRNIDPERYRLCRQ-- 746
I A +NED NAKL+RELK E+ +LK R S P L Q
Sbjct: 348 IKCNAVINEDPNAKLVRELKEEVTRLKDLLRAQGLGDIIDTSMGSLTSSPSSCSLSSQVG 407
Query: 747 --EITSLR-------------MKLHQQERDMAEMQRVWKEKFEQAEKRKLQETKELQKAG 791
+TS++ +L + E+ +AE+ W+EK + E +++ L + G
Sbjct: 408 LTSVTSIQERIMSTPGGEEAIERLKESEKIIAELNETWEEKLRKTEAIRMEREALLAEMG 467
Query: 792 IMFQMD---------NHLPNLVNLNEDPQLSEMLLYMIKEGTTTVGKYKPNSSHDIQLSG 842
+ + D P+LVNLNEDP +SE LLY IK+G T VG+ DI LSG
Sbjct: 468 VAIREDGGTLGVFSPKKTPHLVNLNEDPLMSECLLYYIKDGITRVGQADAERRQDIVLSG 527
Query: 843 VLIADDHCTIK----NFGGT-VSIIPVGEAKTYVNGKHILEITVLRHGDRVILGGDHYFR 897
I ++HC + N G V++ P ++TYVNGK + + LR G+R+I+G +H FR
Sbjct: 528 AHIKEEHCIFRSERSNSGEVIVTLEPCERSETYVNGKRVSQPVQLRSGNRIIMGKNHVFR 587
Query: 898 FNHP--VEVQKGKRPSGRDTPISEGPKDFEFAKNELLMAQ----RSQLEAEIKEAQLKAK 951
FNHP ++ K PS +TP P D+ FA+ ELL Q + ++E ++E ++ K
Sbjct: 588 FNHPEQARAEREKTPSA-ETP--SEPVDWTFAQRELLEKQGIDMKQEMEKRLQEMEILYK 644
Query: 952 EEMMQGIQIAKEMAQQEL--------SSQKAAYESKIKALEAELREESQRKKMQEI 999
+E + + + QQ L S K + E K L LRE+ K+Q I
Sbjct: 645 KEKEEADLL---LEQQRLDADSDSGDDSDKRSCEESWK-LITSLREKLPPSKLQTI 696
>gi|40254834 kinesin family member 1C [Homo sapiens]
Length = 1103
Score = 453 bits (1166), Expect = e-127
Identities = 282/690 (40%), Positives = 400/690 (57%), Gaps = 87/690 (12%)
Query: 357 SQVTVAVRVRPFTKREKIEKASQVVFMSGKEITVEHPDTKQ--VYNFIYDVSFWSFDECH 414
+ V VAVRVRPF RE + A VV M G ++ +P + +F +D S+WS
Sbjct: 4 ASVKVAVRVRPFNARETSQDAKCVVSMQGNTTSIINPKQSKDAPKSFTFDYSYWSHTSTE 63
Query: 415 -PHYASQTTVYEKLAAPLLERAFEGFNTCLFAYGQTGSGKSYTMMGFSE--EPGIIPRFC 471
P +ASQ VY + +L AFEG+N C+FAYGQTG+GKSYTMMG E + GI+P+ C
Sbjct: 64 DPQFASQQQVYRDIGEEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGRQEPGQQGIVPQLC 123
Query: 472 EDLFSQVARKQTQEVSYHIEMSFFEVYNEKIHDLLVCKDENGQRKQPLRVREHPVYGPYV 531
EDLFS+V+ Q+ ++SY +E+S+ E+Y E++ DLL N + + LRVREHP+ GPYV
Sbjct: 124 EDLFSRVSENQSAQLSYSVEVSYMEIYCERVRDLL-----NPKSRGSLRVREHPILGPYV 178
Query: 532 EALSMNIVSSYADIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTKTEFVEGEEH 591
+ LS V+SYADI ++ GNK R AAT MN+ SSRSH+VFT+V TQ + + G +
Sbjct: 179 QDLSKLAVTSYADIADLMDCGNKARTVAATNMNETSSRSHAVFTIVFTQRCHDQLTGLDS 238
Query: 592 DHRITSRINLIDLAGSERCSTAHTNGDRLKEGVSINKSLLTLGKVISALSEQANQR--SV 649
+ S+I+L+DLAGSER ++ G RLKEG +INKSL TLGKVISAL++ +++ S
Sbjct: 239 EK--VSKISLVDLAGSERADSSGARGMRLKEGANINKSLTTLGKVISALADMQSKKRKSD 296
Query: 650 FIPYRESVLTWLLKESLGGNSKTAMIATISPAASNIEETLSTLRYANQARLIVNIAKVNE 709
FIPYR+SVLTWLLKE+LGGNS+TAMIA +SPA N EETLSTLRYA++ + I A +NE
Sbjct: 297 FIPYRDSVLTWLLKENLGGNSRTAMIAALSPADINYEETLSTLRYADRTKQIRCNAIINE 356
Query: 710 DMNAKLIRELKAEIAKLKAAQRNSRNIDPERYRLCRQEITSLRMKL-------------- 755
D NA+LIREL+ E+A+L+ ++ + + E S+R L
Sbjct: 357 DPNARLIRELQEEVARLRELLM-AQGLSASALEGLKTEEGSVRGALPAVSSPPAPVSPSS 415
Query: 756 -----------------------------HQQERDMAEMQRVWKEKFEQAEKRKLQETKE 786
+ E+ +AE+ W+EK + E +++
Sbjct: 416 PTTHNGELEPSFSPNTESQIGPEEAMERLQETEKIIAELNETWEEKLRKTEALRMEREAL 475
Query: 787 LQKAGIMFQMD---------NHLPNLVNLNEDPQLSEMLLYMIKEGTTTVGKYKPNSSHD 837
L + G+ + D P+LVNLNEDP +SE LLY IK+G T VG+ D
Sbjct: 476 LAEMGVAVREDGGTVGVFSPKKTPHLVNLNEDPLMSECLLYHIKDGVTRVGQV----DMD 531
Query: 838 IQLSGVLIADDHCTIKNFGG-----TVSIIPVGEAKTYVNGKHILEITVLRHGDRVILGG 892
I+L+G I + HC ++ V++ P A+TYVNGK + E VL+ G+R+++G
Sbjct: 532 IKLTGQFIREQHCLFRSIPQPDGEVVVTLEPCEGAETYVNGKLVTEPLVLKSGNRIVMGK 591
Query: 893 DHYFRFNHP----VEVQKGKRPSGRDTPISEGPKDFEFAKNELLMAQRSQLEAEIKEAQL 948
+H FRFNHP +E ++G P P SE P D+ FA+ ELL Q ++ E++
Sbjct: 592 NHVFRFNHPEQARLERERGVPPP--PGPPSE-PVDWNFAQKELLEQQGIDIKLEME---- 644
Query: 949 KAKEEMMQGIQIAKEMAQQELSSQKAAYES 978
K +++ + KE A L Q+ +S
Sbjct: 645 KRLQDLENQYRKEKEEADLLLEQQRLYADS 674
>gi|239756270 PREDICTED: StAR-related lipid transfer (START) domain
containing 9 [Homo sapiens]
Length = 4614
Score = 318 bits (816), Expect = 2e-86
Identities = 255/794 (32%), Positives = 385/794 (48%), Gaps = 140/794 (17%)
Query: 357 SQVTVAVRVRPFTKREKIEKASQVVFMSGKEITVEH------PD-----TKQVYNFIYDV 405
+ V VAVRVRP +KRE E +V + GK + + PD ++V F +D
Sbjct: 2 ANVQVAVRVRPLSKRETKEGGRIIVEVDGKVAKIRNLKVDNRPDGFGDSREKVMAFGFDY 61
Query: 406 SFWSFDECHPHYASQTTVYEKLAAPLLERAFEGFNTCLFAYGQTGSGKSYTMMGFSEEPG 465
+WS + P YASQ V++ L +L +G+N CLFAYGQTGSGK+YTM+G G
Sbjct: 62 CYWSVNPEDPQYASQDVVFQDLGMEVLSGVAKGYNICLFAYGQTGSGKTYTMLGTPASVG 121
Query: 466 IIPRFCEDLFSQVARKQTQEVSYHIEMSFFEVYNEKIHDLLVCKDENGQRKQ-PLRVREH 524
+ PR CE LF + + S I++SF E+YNE++ DLL ++GQ+K LRVREH
Sbjct: 122 LTPRICEGLFVREKDCASLPSSCRIKVSFLEIYNERVRDLL---KQSGQKKSYTLRVREH 178
Query: 525 PVYGPYVEALSMNIVSSYADIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTKTE 584
P GPYV+ LS ++V++Y + LE G R TAAT +++ SSRSH++FT+ TQ E
Sbjct: 179 PEMGPYVQGLSQHVVTNYKQVIQLLEEGIANRITAATHVHEASSRSHAIFTIHYTQAILE 238
Query: 585 FVEGEEHDHRITSRINLIDLAGSERCSTAHTNGDRLKEGVSINKSLLTLGKVISALSEQA 644
+ S+INL+DLAGSER ++ DR+ EG +INKSL+TLG VIS L++ +
Sbjct: 239 ----NNLPSEMASKINLVDLAGSERADPSYCK-DRIAEGANINKSLVTLGIVISTLAQNS 293
Query: 645 ----------------------------------NQRSVFIPYRESVLTWLLKESLGGNS 670
++R +IPYR+SVLTWLLK+SLGGNS
Sbjct: 294 QVFSSCQSLNSSVSNGGDSGILSSPSGTSSGGAPSRRQSYIPYRDSVLTWLLKDSLGGNS 353
Query: 671 KTAMIATISPAASNIEETLSTLRYANQARLIVNIAKVNEDMNAKLIRELKAEIAKLKAAQ 730
KT M+A +T+STLRYA+ A+ I+N +VNE ++ Q
Sbjct: 354 KTIMVAI-------TRQTMSTLRYASSAKNIINKPRVNE----------------VRPFQ 390
Query: 731 RNSRNIDPERYRLCRQEITSLRMKLHQQERDMAEMQRVWKEKFE--QAEKRKLQETKELQ 788
+N ++ E +L+ + Q E + ++ + W +K+ QA +
Sbjct: 391 KNFSSLSDE----------NLKELVLQNELKVDQLTKDWTQKWNDWQALMEHYSVDINRR 440
Query: 789 KAGIMFQMDNHLPNLVNLNEDPQLSEMLLYMIKEGTTTVGKYKPNSSHDIQLSGVLIADD 848
+AG++ +D+ LP+L+ L +D + ++LY +K G I D
Sbjct: 441 RAGVV--IDSSLPHLMALEDDVLSTGVVLYHLK--------------------GQWIERD 478
Query: 849 HCTIKNFGGTVSIIPVGEAKTYVNGKHILEITVLRHGDRVILGGDHYFRFNHPVEV---- 904
HCTI + G V + P A+ VNG+ + L G + LG FRFNHP E
Sbjct: 479 HCTITSACGVVVLRPARGARCTVNGREVTASCRLTQGAVITLGKAQKFRFNHPAEAAVLR 538
Query: 905 ---QKGKRPSGRDT----PISEGPKDFEFAKNELLMAQRSQLEAEIKEAQLKAKE-EMMQ 956
Q G+ +GR + + + LL +R LE + E ++ E
Sbjct: 539 QRRQVGEAAAGRGSLEWLDLDGDLAASRLGLSPLLWKERRALEEQCDEDHQTPRDGETSH 598
Query: 957 GIQIAKEMAQ-QELSSQKAAYESK-IKALEAELREESQRKKMQEINNQKANHKIEELEKA 1014
QI ++ + ++L Q A E + K LE + SQ+ K NQ+ + E +
Sbjct: 599 RAQIQQQQSYVEDLRHQILAEEIRAAKELEFDQAWISQQIK----ENQQCLLREETWLAS 654
Query: 1015 KQHLEQEIYVNKKRLEMETLATKQALEDHSIRHARILEALETEKQKIAKEVQILQQN--- 1071
Q +QE V +K LE D I+ + +++ QK +Q+L+++
Sbjct: 655 LQQQQQEDQVAEKELEASVALDAWLQTDPEIQPSPFVQS-----QKRVVHLQLLRRHTLR 709
Query: 1072 ---RNNRDKTFTVQ 1082
RN R K + Q
Sbjct: 710 AAERNVRRKKVSFQ 723
>gi|239750815 PREDICTED: StAR-related lipid transfer (START) domain
containing 9 [Homo sapiens]
Length = 4614
Score = 318 bits (816), Expect = 2e-86
Identities = 255/794 (32%), Positives = 385/794 (48%), Gaps = 140/794 (17%)
Query: 357 SQVTVAVRVRPFTKREKIEKASQVVFMSGKEITVEH------PD-----TKQVYNFIYDV 405
+ V VAVRVRP +KRE E +V + GK + + PD ++V F +D
Sbjct: 2 ANVQVAVRVRPLSKRETKEGGRIIVEVDGKVAKIRNLKVDNRPDGFGDSREKVMAFGFDY 61
Query: 406 SFWSFDECHPHYASQTTVYEKLAAPLLERAFEGFNTCLFAYGQTGSGKSYTMMGFSEEPG 465
+WS + P YASQ V++ L +L +G+N CLFAYGQTGSGK+YTM+G G
Sbjct: 62 CYWSVNPEDPQYASQDVVFQDLGMEVLSGVAKGYNICLFAYGQTGSGKTYTMLGTPASVG 121
Query: 466 IIPRFCEDLFSQVARKQTQEVSYHIEMSFFEVYNEKIHDLLVCKDENGQRKQ-PLRVREH 524
+ PR CE LF + + S I++SF E+YNE++ DLL ++GQ+K LRVREH
Sbjct: 122 LTPRICEGLFVREKDCASLPSSCRIKVSFLEIYNERVRDLL---KQSGQKKSYTLRVREH 178
Query: 525 PVYGPYVEALSMNIVSSYADIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTKTE 584
P GPYV+ LS ++V++Y + LE G R TAAT +++ SSRSH++FT+ TQ E
Sbjct: 179 PEMGPYVQGLSQHVVTNYKQVIQLLEEGIANRITAATHVHEASSRSHAIFTIHYTQAILE 238
Query: 585 FVEGEEHDHRITSRINLIDLAGSERCSTAHTNGDRLKEGVSINKSLLTLGKVISALSEQA 644
+ S+INL+DLAGSER ++ DR+ EG +INKSL+TLG VIS L++ +
Sbjct: 239 ----NNLPSEMASKINLVDLAGSERADPSYCK-DRIAEGANINKSLVTLGIVISTLAQNS 293
Query: 645 ----------------------------------NQRSVFIPYRESVLTWLLKESLGGNS 670
++R +IPYR+SVLTWLLK+SLGGNS
Sbjct: 294 QVFSSCQSLNSSVSNGGDSGILSSPSGTSSGGAPSRRQSYIPYRDSVLTWLLKDSLGGNS 353
Query: 671 KTAMIATISPAASNIEETLSTLRYANQARLIVNIAKVNEDMNAKLIRELKAEIAKLKAAQ 730
KT M+A +T+STLRYA+ A+ I+N +VNE ++ Q
Sbjct: 354 KTIMVAI-------TRQTMSTLRYASSAKNIINKPRVNE----------------VRPFQ 390
Query: 731 RNSRNIDPERYRLCRQEITSLRMKLHQQERDMAEMQRVWKEKFE--QAEKRKLQETKELQ 788
+N ++ E +L+ + Q E + ++ + W +K+ QA +
Sbjct: 391 KNFSSLSDE----------NLKELVLQNELKVDQLTKDWTQKWNDWQALMEHYSVDINRR 440
Query: 789 KAGIMFQMDNHLPNLVNLNEDPQLSEMLLYMIKEGTTTVGKYKPNSSHDIQLSGVLIADD 848
+AG++ +D+ LP+L+ L +D + ++LY +K G I D
Sbjct: 441 RAGVV--IDSSLPHLMALEDDVLSTGVVLYHLK--------------------GQWIERD 478
Query: 849 HCTIKNFGGTVSIIPVGEAKTYVNGKHILEITVLRHGDRVILGGDHYFRFNHPVEV---- 904
HCTI + G V + P A+ VNG+ + L G + LG FRFNHP E
Sbjct: 479 HCTITSACGVVVLRPARGARCTVNGREVTASCRLTQGAVITLGKAQKFRFNHPAEAAVLR 538
Query: 905 ---QKGKRPSGRDT----PISEGPKDFEFAKNELLMAQRSQLEAEIKEAQLKAKE-EMMQ 956
Q G+ +GR + + + LL +R LE + E ++ E
Sbjct: 539 QRRQVGEAAAGRGSLEWLDLDGDLAASRLGLSPLLWKERRALEEQCDEDHQTPRDGETSH 598
Query: 957 GIQIAKEMAQ-QELSSQKAAYESK-IKALEAELREESQRKKMQEINNQKANHKIEELEKA 1014
QI ++ + ++L Q A E + K LE + SQ+ K NQ+ + E +
Sbjct: 599 RAQIQQQQSYVEDLRHQILAEEIRAAKELEFDQAWISQQIK----ENQQCLLREETWLAS 654
Query: 1015 KQHLEQEIYVNKKRLEMETLATKQALEDHSIRHARILEALETEKQKIAKEVQILQQN--- 1071
Q +QE V +K LE D I+ + +++ QK +Q+L+++
Sbjct: 655 LQQQQQEDQVAEKELEASVALDAWLQTDPEIQPSPFVQS-----QKRVVHLQLLRRHTLR 709
Query: 1072 ---RNNRDKTFTVQ 1082
RN R K + Q
Sbjct: 710 AAERNVRRKKVSFQ 723
>gi|239745175 PREDICTED: StAR-related lipid transfer (START) domain
containing 9 [Homo sapiens]
Length = 4614
Score = 318 bits (816), Expect = 2e-86
Identities = 255/794 (32%), Positives = 385/794 (48%), Gaps = 140/794 (17%)
Query: 357 SQVTVAVRVRPFTKREKIEKASQVVFMSGKEITVEH------PD-----TKQVYNFIYDV 405
+ V VAVRVRP +KRE E +V + GK + + PD ++V F +D
Sbjct: 2 ANVQVAVRVRPLSKRETKEGGRIIVEVDGKVAKIRNLKVDNRPDGFGDSREKVMAFGFDY 61
Query: 406 SFWSFDECHPHYASQTTVYEKLAAPLLERAFEGFNTCLFAYGQTGSGKSYTMMGFSEEPG 465
+WS + P YASQ V++ L +L +G+N CLFAYGQTGSGK+YTM+G G
Sbjct: 62 CYWSVNPEDPQYASQDVVFQDLGMEVLSGVAKGYNICLFAYGQTGSGKTYTMLGTPASVG 121
Query: 466 IIPRFCEDLFSQVARKQTQEVSYHIEMSFFEVYNEKIHDLLVCKDENGQRKQ-PLRVREH 524
+ PR CE LF + + S I++SF E+YNE++ DLL ++GQ+K LRVREH
Sbjct: 122 LTPRICEGLFVREKDCASLPSSCRIKVSFLEIYNERVRDLL---KQSGQKKSYTLRVREH 178
Query: 525 PVYGPYVEALSMNIVSSYADIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTKTE 584
P GPYV+ LS ++V++Y + LE G R TAAT +++ SSRSH++FT+ TQ E
Sbjct: 179 PEMGPYVQGLSQHVVTNYKQVIQLLEEGIANRITAATHVHEASSRSHAIFTIHYTQAILE 238
Query: 585 FVEGEEHDHRITSRINLIDLAGSERCSTAHTNGDRLKEGVSINKSLLTLGKVISALSEQA 644
+ S+INL+DLAGSER ++ DR+ EG +INKSL+TLG VIS L++ +
Sbjct: 239 ----NNLPSEMASKINLVDLAGSERADPSYCK-DRIAEGANINKSLVTLGIVISTLAQNS 293
Query: 645 ----------------------------------NQRSVFIPYRESVLTWLLKESLGGNS 670
++R +IPYR+SVLTWLLK+SLGGNS
Sbjct: 294 QVFSSCQSLNSSVSNGGDSGILSSPSGTSSGGAPSRRQSYIPYRDSVLTWLLKDSLGGNS 353
Query: 671 KTAMIATISPAASNIEETLSTLRYANQARLIVNIAKVNEDMNAKLIRELKAEIAKLKAAQ 730
KT M+A +T+STLRYA+ A+ I+N +VNE ++ Q
Sbjct: 354 KTIMVAI-------TRQTMSTLRYASSAKNIINKPRVNE----------------VRPFQ 390
Query: 731 RNSRNIDPERYRLCRQEITSLRMKLHQQERDMAEMQRVWKEKFE--QAEKRKLQETKELQ 788
+N ++ E +L+ + Q E + ++ + W +K+ QA +
Sbjct: 391 KNFSSLSDE----------NLKELVLQNELKVDQLTKDWTQKWNDWQALMEHYSVDINRR 440
Query: 789 KAGIMFQMDNHLPNLVNLNEDPQLSEMLLYMIKEGTTTVGKYKPNSSHDIQLSGVLIADD 848
+AG++ +D+ LP+L+ L +D + ++LY +K G I D
Sbjct: 441 RAGVV--IDSSLPHLMALEDDVLSTGVVLYHLK--------------------GQWIERD 478
Query: 849 HCTIKNFGGTVSIIPVGEAKTYVNGKHILEITVLRHGDRVILGGDHYFRFNHPVEV---- 904
HCTI + G V + P A+ VNG+ + L G + LG FRFNHP E
Sbjct: 479 HCTITSACGVVVLRPARGARCTVNGREVTASCRLTQGAVITLGKAQKFRFNHPAEAAVLR 538
Query: 905 ---QKGKRPSGRDT----PISEGPKDFEFAKNELLMAQRSQLEAEIKEAQLKAKE-EMMQ 956
Q G+ +GR + + + LL +R LE + E ++ E
Sbjct: 539 QRRQVGEAAAGRGSLEWLDLDGDLAASRLGLSPLLWKERRALEEQCDEDHQTPRDGETSH 598
Query: 957 GIQIAKEMAQ-QELSSQKAAYESK-IKALEAELREESQRKKMQEINNQKANHKIEELEKA 1014
QI ++ + ++L Q A E + K LE + SQ+ K NQ+ + E +
Sbjct: 599 RAQIQQQQSYVEDLRHQILAEEIRAAKELEFDQAWISQQIK----ENQQCLLREETWLAS 654
Query: 1015 KQHLEQEIYVNKKRLEMETLATKQALEDHSIRHARILEALETEKQKIAKEVQILQQN--- 1071
Q +QE V +K LE D I+ + +++ QK +Q+L+++
Sbjct: 655 LQQQQQEDQVAEKELEASVALDAWLQTDPEIQPSPFVQS-----QKRVVHLQLLRRHTLR 709
Query: 1072 ---RNNRDKTFTVQ 1082
RN R K + Q
Sbjct: 710 AAERNVRRKKVSFQ 723
>gi|4758646 kinesin family member 3B [Homo sapiens]
Length = 747
Score = 268 bits (685), Expect = 3e-71
Identities = 179/485 (36%), Positives = 277/485 (57%), Gaps = 35/485 (7%)
Query: 353 KVENSQ-VTVAVRVRPFTKREKIEKASQVVFMSGK--EITVEHPDTKQVYNFIYDV-SFW 408
K+++S+ V V VR RP +EK +VV + K +++V++P +++ +
Sbjct: 3 KLKSSESVRVVVRCRPMNGKEKAASYDKVVDVDVKLGQVSVKNPK-----GTAHEMPKTF 57
Query: 409 SFDECHPHYASQTTVYEKLAAPLLERAFEGFNTCLFAYGQTGSGKSYTMMGFSEEP---G 465
+FD + A Q +Y++ PL++ +GFN +FAYGQTG+GK+YTM G +P G
Sbjct: 58 TFDAVYDWNAKQFELYDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTMEGIRGDPEKRG 117
Query: 466 IIPRFCEDLFSQVARKQTQEVSYHIEMSFFEVYNEKIHDLLVCKDENGQRKQPLRVREHP 525
+IP + +F+ ++R Q Q+ Y + S+ E+Y E+I DLL KD+ + L ++E P
Sbjct: 118 VIPNSFDHIFTHISRSQNQQ--YLVRASYLEIYQEEIRDLL-SKDQTKR----LELKERP 170
Query: 526 VYGPYVEALSMNIVSSYADIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTKTEF 585
G YV+ LS + S +I+ + +GN+ R+ AT MN+ SSRSH++F + + ++
Sbjct: 171 DTGVYVKDLSSFVTKSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIECSEVG- 229
Query: 586 VEGEEHDHRITSRINLIDLAGSERCSTAHTNGDRLKEGVSINKSLLTLGKVISALSEQAN 645
++GE H ++NL+DLAGSER + G+RLKE IN SL LG VISAL +
Sbjct: 230 LDGENHIR--VGKLNLVDLAGSERQAKTGAQGERLKEATKINLSLSALGNVISAL---VD 284
Query: 646 QRSVFIPYRESVLTWLLKESLGGNSKTAMIATISPAASNIEETLSTLRYANQARLIVNIA 705
+S IPYR+S LT LL++SLGGN+KT M+A + PA+ N+EETL+TLRYAN+A+ I N
Sbjct: 285 GKSTHIPYRDSKLTRLLQDSLGGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNKP 344
Query: 706 KVNEDMNAKLIRELKAEIAKLKAAQRNSRNIDPERYRLCRQEITSLRMKLHQQERDMAEM 765
+VNED L+RE + EIA+LK AQ R+I + R R+E ++E + E
Sbjct: 345 RVNEDPKDALLREFQEEIARLK-AQLEKRSIGRRKRREKRREGGGSGGGGEEEEEEGEEG 403
Query: 766 QR-------VWKEKFE--QAEKRKLQETKELQKAGIMFQMDNHLPNLVNLNEDPQLSEML 816
+ W+E+ E + EKR + E L M + + +L + +EML
Sbjct: 404 EEEGDDKDDYWREQQEKLEIEKRAIVEDHSLVAEEKMRLLKEKEKKMEDLRREKDAAEML 463
Query: 817 LYMIK 821
IK
Sbjct: 464 GAKIK 468
Score = 37.0 bits (84), Expect = 0.16
Identities = 45/208 (21%), Positives = 97/208 (46%), Gaps = 24/208 (11%)
Query: 917 ISEGPKDFEFAKNELLMAQRSQLEAEIKEAQL---KAKEEMMQGIQIAKEMAQQELSSQK 973
++E PKD A + ++L+A++++ + K +E+ +G ++E ++
Sbjct: 346 VNEDPKD---ALLREFQEEIARLKAQLEKRSIGRRKRREKRREGGGSGGGGEEEEEEGEE 402
Query: 974 AAYESKIKA---LEAELREESQRKKMQEINNQKANHK---IEELEKAKQHLEQE------ 1021
E K E + + E +++ + E ++ A K ++E EK + L +E
Sbjct: 403 GEEEGDDKDDYWREQQEKLEIEKRAIVEDHSLVAEEKMRLLKEKEKKMEDLRREKDAAEM 462
Query: 1022 IYVNKKRLEMETLATKQALEDHSIRHARILEALETE-KQKIAKEVQILQQNRNNRDKTFT 1080
+ K +E + L + + DH+ +ILE E ++ +E +I QQ + ++T
Sbjct: 463 LGAKIKAMESKLLVGGKNIVDHTNEQQKILEQKRQEIAEQKRREREIQQQMESRDEETLE 522
Query: 1081 VQTTWSSMKLSMMIQEANAISSKLKTYY 1108
++ T+SS++ QE + + KLK +
Sbjct: 523 LKETYSSLQ-----QEVDIKTKKLKKLF 545
>gi|150010604 kinesin family member 4B [Homo sapiens]
Length = 1234
Score = 263 bits (671), Expect = 1e-69
Identities = 234/805 (29%), Positives = 385/805 (47%), Gaps = 109/805 (13%)
Query: 353 KVENSQVTVAVRVRPFTKREKIEKASQVV-FMSGKEITVEHPDTKQVYNFIYDVSFWSFD 411
+V+ V VA+R RP +E E + F+ G+ V D Y+F+ FD
Sbjct: 4 EVKGIPVRVALRCRPLVPKEISEGCQMCLSFVPGETQVVVGTDKSFTYDFV-------FD 56
Query: 412 ECHPHYASQTTVYEKLAAPLLERAFEGFNTCLFAYGQTGSGKSYTMMGF-----SEEP-- 464
C Q V+ K APL++ F+G+N + AYGQTGSGK+Y+M G EP
Sbjct: 57 PC----TEQEEVFNKAVAPLIKGIFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTV 112
Query: 465 GIIPRFCEDLFSQVARKQTQEVSYHIEMSFFEVYNEKIHDLLVCKDENGQRKQPLRVREH 524
GIIPR + LF ++ +K E + +++S+ E+YNE+I DLL E Q + +RE
Sbjct: 113 GIIPRVIQLLFKEIDKKSDFE--FTLKVSYLEIYNEEILDLLCPSREKAQ----INIRED 166
Query: 525 PVYGPYVEALSMNIVSSYADIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTKTE 584
P G + L+ V D S LE GN R A+T MN +SSRSH++FT+ + Q K
Sbjct: 167 PKEGIKIVGLTEKTVLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISIEQRKKS 226
Query: 585 FVEGEEHDHRITSRINLIDLAGSERCSTAHTNGDRLKEGVSINKSLLTLGKVISALSEQA 644
+ + S+++L+DLAGSER GDRLKEG++IN+ LL LG VISAL +
Sbjct: 227 -----DKNCSFRSKLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGD-- 279
Query: 645 NQRSVFIPYRESVLTWLLKESLGGNSKTAMIATISPAASNIEETLSTLRYANQARLIVNI 704
+++ F+PYR+S LT LL++SLGGNS T MIA +SPA SN+EETLSTLRYA++AR I N
Sbjct: 280 DKKGSFVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLSTLRYADRARKIKNK 339
Query: 705 AKVNEDMNAKLIRELKAEIAKLK--------AAQRNSRNIDP--------ERYRLCRQEI 748
VN D + + LK ++ +L+ S N +P E+ + +E
Sbjct: 340 PIVNIDPHTAELNHLKQQVQQLQVLLLQAHGGTLPGSINAEPSENLQSLMEKNQSLVEEN 399
Query: 749 TSLRMKLHQQERDMAEM--QRVWKEKFEQAEKRKLQETKELQKAGIMFQMDNHLPNLVNL 806
L L + A+M + + E+ + KL+E ++ + ++D L LV
Sbjct: 400 EKLSRCLSKAAGQTAQMLERIILTEQVNEKLNAKLEELRQ----HVACKLD--LQKLVET 453
Query: 807 NEDPQLSE--MLLYMIKEGTTTVGKYKPNSSHDIQLSGVLIADDHCTIKNFGGTVSIIPV 864
ED +L E ++ +++ T QLS +A CT V
Sbjct: 454 LEDQELKENVEIICNLQQLIT-------------QLSDETVA---CTAAAIDTAVE--EE 495
Query: 865 GEAKTYVNGKHILEITVLRHGDRVILGGDHYFRFNHPVEVQKG--KRPSGRDTPISEGPK 922
+ +T + +H N+ + +++ ++ + D + P
Sbjct: 496 AQVETSPETSRSSDAFTTQHALHQAQMSKEVVELNNALALKEALVRKMTQNDNQLQ--PI 553
Query: 923 DFEFAKNELLMAQRSQLEAEIKEAQLKAKEEMMQGIQIAKEMAQQELSSQK-----AAYE 977
F++ N LE E+ Q K KEE+++ +Q AK+ Q S+ E
Sbjct: 554 QFQYQDN------IKNLELEVINLQ-KEKEELVRELQTAKKNVNQAKLSEHRHKLLQELE 606
Query: 978 SKIKALEAELREESQRKKMQEINNQKANHKIEELEKAKQHLEQEIYVNK-KRLEMETLAT 1036
+I L+ +L E+S+ K++ E E+ L QEI++ K +R+++
Sbjct: 607 GQIADLKKKLNEQSKLLKLK-----------ESTERTVSKLNQEIWMMKNQRVQLMRQMK 655
Query: 1037 KQALEDHSIRHARILEALETEKQKIAKEVQILQQNRNNRDKTF-----TVQTTWSSMKLS 1091
+ A + + + E ++ +++ ++ ++L+ RN + ++ T + ++ +L
Sbjct: 656 EDAEKFRQWKQKKDKEVIQLKERDRKRQYELLKLERNFQKQSSVLRRKTEEAAAANKRLK 715
Query: 1092 MMIQEANAISSKLKTYYVFGRHDIS 1116
+Q+ ++ K K G+ I+
Sbjct: 716 DALQKQREVTDKRKETQSHGKEGIA 740
Score = 53.1 bits (126), Expect = 2e-06
Identities = 95/481 (19%), Positives = 208/481 (43%), Gaps = 52/481 (10%)
Query: 621 KEGVSINKSLLTLGKVISALSEQANQ-RSVFIPYRESVLTWLLKESLGGNSKTAMIATIS 679
KE V +N +L ++ +++ NQ + + Y++++ L+ K ++ +
Sbjct: 524 KEVVELNNALALKEALVRKMTQNDNQLQPIQFQYQDNIKNLELEVINLQKEKEELVRELQ 583
Query: 680 PAASNIEET-LSTLRYANQARLIVNIAKVNEDMNAKLIRELKAEIAKLK-AAQRNSRNID 737
A N+ + LS R+ L IA + + +N + +++ KLK + +R ++
Sbjct: 584 TAKKNVNQAKLSEHRHKLLQELEGQIADLKKKLNEQ------SKLLKLKESTERTVSKLN 637
Query: 738 PERYRLCRQEITSLRMKLHQQERDMAEMQRVWKEKFE----QAEKRKLQETKELQKAGIM 793
E + + Q R++L +Q ++ AE R WK+K + Q ++R + EL K
Sbjct: 638 QEIWMMKNQ-----RVQLMRQMKEDAEKFRQWKQKKDKEVIQLKERDRKRQYELLKLERN 692
Query: 794 FQMDNHLPNLVNLNEDPQLSEMLLYMIKEGTTTVGKYKPNSSHDIQLSGVLIADDHCTIK 853
FQ + + E ++ L +++ K K SH + G+ ++
Sbjct: 693 FQKQSSVLRR-KTEEAAAANKRLKDALQKQREVTDKRKETQSHGKE--GIA-----ARVR 744
Query: 854 NF-GGTVSI-IPVGEAKTYVNGKHILEITVLRHGDRVILGGDHYFRFNHPVEVQK----- 906
N+ G + + + EAK ++N +LE + D V L R N P +++K
Sbjct: 745 NWLGNEIEVMVSTEEAKRHLN--DLLEDRKILAQDVVQLKEKKESRENPPPKLRKCTFSL 802
Query: 907 ----GKRPSGRD---TPISEGPKDFEFAKNELLMAQRSQLEAEIKEAQLKAKEEMMQGIQ 959
G+ D I + E ++ Q+ L+AE ++ + E + ++
Sbjct: 803 SEVHGQVLESEDCITKQIESLETEMELRSAQIADLQQKLLDAESEDRPKQCWENIATILE 862
Query: 960 IAKEMAQQELSSQKAAYESKIKALEAELRE-ESQRKKMQEINNQKANHKIE-------EL 1011
+ A + L + + + + LE LR+ ++ MQ++ ++ NH E EL
Sbjct: 863 --AKCALKYLIGELVSSKIHVTKLENSLRQSKASCADMQKMLFEEQNHFSEIETELQAEL 920
Query: 1012 EKAKQHLEQEIYVNKKRLEMETLATKQALEDHSIRHARILEALETEKQKIAKEVQILQQN 1071
+ +Q ++++ +L+ +A KQ + S + +++ L+ + +++ K ++ +QN
Sbjct: 921 VRMEQQHQEKVLYLVSQLQESQMAEKQLEKSASEKEQQLVSTLQCQDEELEKMREVCEQN 980
Query: 1072 R 1072
+
Sbjct: 981 Q 981
>gi|116686122 kinesin family member 4 [Homo sapiens]
Length = 1232
Score = 260 bits (664), Expect = 9e-69
Identities = 226/811 (27%), Positives = 380/811 (46%), Gaps = 103/811 (12%)
Query: 353 KVENSQVTVAVRVRPFTKREKIEKASQVV-FMSGKEITVEHPDTKQVYNFIYDVSFWSFD 411
+V+ V VA+R RP +E E + F+ G+ V D Y+F++D S
Sbjct: 4 EVKGIPVRVALRCRPLVPKEISEGCQMCLSFVPGEPQVVVGTDKSFTYDFVFDPS----- 58
Query: 412 ECHPHYASQTTVYEKLAAPLLERAFEGFNTCLFAYGQTGSGKSYTMMGF-----SEEP-- 464
Q V+ APL++ F+G+N + AYGQTGSGK+Y+M G EP
Sbjct: 59 ------TEQEEVFNTAVAPLIKGVFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTV 112
Query: 465 GIIPRFCEDLFSQVARKQTQEVSYHIEMSFFEVYNEKIHDLLVCKDENGQRKQPLRVREH 524
G+IPR + LF ++ +K E + +++S+ E+YNE+I DLL E Q + +RE
Sbjct: 113 GVIPRVIQLLFKEIDKKSDFE--FTLKVSYLEIYNEEILDLLCPSREKAQ----INIRED 166
Query: 525 PVYGPYVEALSMNIVSSYADIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTKTE 584
P G + L+ V D S LE GN R A+T MN +SSRSH++FT+ + Q K
Sbjct: 167 PKEGIKIVGLTEKTVLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISLEQRKKS 226
Query: 585 FVEGEEHDHRITSRINLIDLAGSERCSTAHTNGDRLKEGVSINKSLLTLGKVISALSEQA 644
+ + S+++L+DLAGSER GDRLKEG++IN+ LL LG VISAL +
Sbjct: 227 -----DKNSSFRSKLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGD-- 279
Query: 645 NQRSVFIPYRESVLTWLLKESLGGNSKTAMIATISPAASNIEETLSTLRYANQARLIVNI 704
+++ F+PYR+S LT LL++SLGGNS T MIA +SPA SN+EETL+TLRYA++AR I N
Sbjct: 280 DKKGGFVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLNTLRYADRARKIKNK 339
Query: 705 AKVNEDMNAKLIRELKAEIAKLK--------AAQRNSRNIDP-ERYRLCRQEITSLRMKL 755
VN D + LK ++ +L+ S ++P E + ++ SL +
Sbjct: 340 PIVNIDPQTAELNHLKQQVQQLQVLLLQAHGGTLPGSITVEPSENLQSLMEKNQSLVEEN 399
Query: 756 HQQERDMAEMQRVWKEKF------EQAEKRKLQETKELQKAGIMFQMDNHLPNLVNLNED 809
+ R ++E + EQA ++ + +EL++ ++D L LV ED
Sbjct: 400 EKLSRGLSEAAGQTAQMLERIILTEQANEKMNAKLEELRQHAAC-KLD--LQKLVETLED 456
Query: 810 PQLSEMLLYMIKEGTTTVGKYKPNSSHDIQLSGVLIADDHCTIKNFGGTVSIIPVGEAKT 869
+L E + + ++Q ++D+ ++ + +T
Sbjct: 457 QELKENVEIIC----------------NLQQLITQLSDETVACMAAAIDTAVEQEAQVET 500
Query: 870 YVNGKHILEITVLRHGDRVILGGDHYFRFNHPVEVQKGKRPSGRDTPISEGPKDFEFAKN 929
+ +H R N + +++ P +++ N
Sbjct: 501 SPETSRSSDAFTTQHALRQAQMSKELVELNKALALKEALARKMTQNDSQLQPIQYQYQDN 560
Query: 930 ELLMAQRSQLEAEIKEAQLKAKEEMMQGIQIAKEMAQQELSSQK-----AAYESKIKALE 984
+LE E+ Q K KEE++ +Q AK+ A Q S++ E +I L+
Sbjct: 561 ------IKELELEVINLQ-KEKEELVLELQTAKKDANQAKLSERRRKRLQELEGQIADLK 613
Query: 985 AELREESQRKKMQEINNQKANHKIEELEKAKQHLEQEIYVNK-KRLEMETLATKQALEDH 1043
+L E+S+ K++ E E+ L QEI + K +R+++ + A +
Sbjct: 614 KKLNEQSKLLKLK-----------ESTERTVSKLNQEIRMMKNQRVQLMRQMKEDAEKFR 662
Query: 1044 SIRHARILEALETEKQKIAKEVQILQQNRN-----NRDKTFTVQTTWSSMKLSMMIQEAN 1098
+ + E ++ +++ ++ ++L+ RN N + T + ++ +L +Q+
Sbjct: 663 QWKQKKDKEVIQLKERDRKRQYELLKLERNFQKQSNVLRRKTEEAAAANKRLKDALQKQR 722
Query: 1099 AISSKLKTYYVFGRHDISDKSSSDTSIRVRN 1129
++ K R + + T+ RV+N
Sbjct: 723 EVADK--------RKETQSRGMEGTAARVKN 745
Score = 52.4 bits (124), Expect = 4e-06
Identities = 101/495 (20%), Positives = 210/495 (42%), Gaps = 80/495 (16%)
Query: 621 KEGVSINKSLLTLGKVISALSEQANQ-RSVFIPYRESVLTWLLKESLGGNSKTAMIATIS 679
KE V +NK+L + +++ +Q + + Y++++ L+ K ++ +
Sbjct: 524 KELVELNKALALKEALARKMTQNDSQLQPIQYQYQDNIKELELEVINLQKEKEELVLELQ 583
Query: 680 PAASNIEET-LSTLRYANQARLIVNIAKVNEDMNAKLIRELKAEIAKLKAAQRNSRNIDP 738
A + + LS R L IA + + +N + +++ KLK + + +
Sbjct: 584 TAKKDANQAKLSERRRKRLQELEGQIADLKKKLNEQ------SKLLKLKESTERTVSKLN 637
Query: 739 ERYRLCRQEITSLRMKLHQQERDMAEMQRVWKEKFE----QAEKRKLQETKELQKAGIMF 794
+ R+ + + R++L +Q ++ AE R WK+K + Q ++R + EL K F
Sbjct: 638 QEIRMMKNQ----RVQLMRQMKEDAEKFRQWKQKKDKEVIQLKERDRKRQYELLKLERNF 693
Query: 795 QMDNHLPNLVNLNEDPQLSEMLLYMIKEGTTTVGKYKPNSSHDIQLSGVLIADDHCTIKN 854
Q +++ E ++ L +++ K K S ++ + +KN
Sbjct: 694 QKQSNVLRR-KTEEAAAANKRLKDALQKQREVADKRKETQSRGMEGTA-------ARVKN 745
Query: 855 F-GGTVSI-IPVGEAKTYVNGKHILEITVLRHGDRVILGGDHYFRFNHPVEVQKGKRPSG 912
+ G + + + EAK ++N +LE DR IL D V K K+ SG
Sbjct: 746 WLGNEIEVMVSTEEAKRHLN--DLLE-------DRKILAQD--------VAQLKEKKESG 788
Query: 913 RDTP----------------ISEG-----------PKDFEFAKNELLMAQRSQLEAEIKE 945
+ P +SE + EF ++ Q+ L+AE E
Sbjct: 789 ENPPPKLRRRTFSLTEVRGQVSESEDSITKQIESLETEMEFRSAQIADLQQKLLDAE-SE 847
Query: 946 AQLKAKEEMMQGIQIAKEMAQQELSSQKAAYESKIKALEAELRE-ESQRKKMQEINNQKA 1004
+ K + E + I AK A + L + + + ++ LE+ L++ ++ MQ++ ++
Sbjct: 848 DRPKQRWENIATILEAK-CALKYLIGELVSSKIQVSKLESSLKQSKTSCADMQKMLFEER 906
Query: 1005 NHKIE-------ELEKAKQHLEQEIYVNKKRLEMETLATKQALEDHSIRHARILEALETE 1057
NH E EL + +Q ++++ +L+ +A KQ E S + ++L L+ +
Sbjct: 907 NHFAEIETELQAELVRMEQQHQEKVLYLLSQLQQSQMAEKQLEESVSEKEQQLLSTLKCQ 966
Query: 1058 KQKIAKEVQILQQNR 1072
+++ K ++ +QN+
Sbjct: 967 DEELEKMREVCEQNQ 981
>gi|170784809 kinesin family member 17 isoform b [Homo sapiens]
Length = 1028
Score = 260 bits (664), Expect = 9e-69
Identities = 172/452 (38%), Positives = 252/452 (55%), Gaps = 33/452 (7%)
Query: 359 VTVAVRVRPFTKREKIEKASQVVFM--SGKEITVEHPDT--KQVYNFIYDVSFWSFDECH 414
V V VR RP +RE+ + VV + + + +++P + F +D ++ H
Sbjct: 6 VKVVVRCRPMNQRERELRCQPVVTVDCARAQCCIQNPGAADEPPKQFTFDGAY------H 59
Query: 415 PHYASQTTVYEKLAAPLLERAFEGFNTCLFAYGQTGSGKSYTMMGFSEEP---GIIPRFC 471
+ ++ +Y ++A PL+E EG+N +FAYGQTGSGKS+TM G + P GIIPR
Sbjct: 60 VDHVTEQ-IYNEIAYPLVEGVTEGYNGTIFAYGQTGSGKSFTMQGLPDPPSQRGIIPRAF 118
Query: 472 EDLFSQVARKQTQEVSYHIEMSFFEVYNEKIHDLLVCKDENGQRKQPLRVREHPVYGPYV 531
E +F V + + + + S+ E+YNE + DLL KQ L ++EHP G YV
Sbjct: 119 EHVFESV--QCAENTKFLVRASYLEIYNEDVRDLL-----GADTKQKLELKEHPEKGVYV 171
Query: 532 EALSMNIVSSYADIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTKTEFVEGEEH 591
+ LSM+ V S A + +E G K R+ T MN SSRSHS+FT+ + + V+
Sbjct: 172 KGLSMHTVHSVAQCEHIMETGWKNRSVGYTLMNKDSSRSHSIFTISIEMSA---VDERGK 228
Query: 592 DHRITSRINLIDLAGSERCSTAHTNGDRLKEGVSINKSLLTLGKVISALSEQANQRSVFI 651
DH ++NL+DLAGSER S G+RLKE IN SL LG VISAL + R +
Sbjct: 229 DHLRAGKLNLVDLAGSERQSKTGATGERLKEATKINLSLSALGNVISAL---VDGRCKHV 285
Query: 652 PYRESVLTWLLKESLGGNSKTAMIATISPAASNIEETLSTLRYANQARLIVNIAKVNEDM 711
PYR+S LT LL++SLGGN+KT M+A +SPA +N +ETLSTLRYAN+A+ I N ++NED
Sbjct: 286 PYRDSKLTRLLQDSLGGNTKTLMVACLSPADNNYDETLSTLRYANRAKNIRNKPRINEDP 345
Query: 712 NAKLIRELKAEIAKLKAAQRNSRNIDPERYRLCRQ---EITSLRMKLHQQ---ERDMAEM 765
L+RE + EI KLKA + L RQ + + KL Q + D+
Sbjct: 346 KDALLREYQEEIKKLKAILTQQMSPSSLSALLSRQVPPDPVQVEEKLLPQPVIQHDVEAE 405
Query: 766 QRVWKEKFEQAEKRKLQETKELQKAGIMFQMD 797
+++ +E++E+ R + K Q++ + D
Sbjct: 406 KQLIREEYEERLARLKADYKAEQESRARLEED 437
>gi|170784807 kinesin family member 17 isoform a [Homo sapiens]
Length = 1029
Score = 260 bits (664), Expect = 9e-69
Identities = 172/452 (38%), Positives = 252/452 (55%), Gaps = 33/452 (7%)
Query: 359 VTVAVRVRPFTKREKIEKASQVVFM--SGKEITVEHPDT--KQVYNFIYDVSFWSFDECH 414
V V VR RP +RE+ + VV + + + +++P + F +D ++ H
Sbjct: 6 VKVVVRCRPMNQRERELRCQPVVTVDCARAQCCIQNPGAADEPPKQFTFDGAY------H 59
Query: 415 PHYASQTTVYEKLAAPLLERAFEGFNTCLFAYGQTGSGKSYTMMGFSEEP---GIIPRFC 471
+ ++ +Y ++A PL+E EG+N +FAYGQTGSGKS+TM G + P GIIPR
Sbjct: 60 VDHVTEQ-IYNEIAYPLVEGVTEGYNGTIFAYGQTGSGKSFTMQGLPDPPSQRGIIPRAF 118
Query: 472 EDLFSQVARKQTQEVSYHIEMSFFEVYNEKIHDLLVCKDENGQRKQPLRVREHPVYGPYV 531
E +F V + + + + S+ E+YNE + DLL KQ L ++EHP G YV
Sbjct: 119 EHVFESV--QCAENTKFLVRASYLEIYNEDVRDLL-----GADTKQKLELKEHPEKGVYV 171
Query: 532 EALSMNIVSSYADIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTKTEFVEGEEH 591
+ LSM+ V S A + +E G K R+ T MN SSRSHS+FT+ + + V+
Sbjct: 172 KGLSMHTVHSVAQCEHIMETGWKNRSVGYTLMNKDSSRSHSIFTISIEMSA---VDERGK 228
Query: 592 DHRITSRINLIDLAGSERCSTAHTNGDRLKEGVSINKSLLTLGKVISALSEQANQRSVFI 651
DH ++NL+DLAGSER S G+RLKE IN SL LG VISAL + R +
Sbjct: 229 DHLRAGKLNLVDLAGSERQSKTGATGERLKEATKINLSLSALGNVISAL---VDGRCKHV 285
Query: 652 PYRESVLTWLLKESLGGNSKTAMIATISPAASNIEETLSTLRYANQARLIVNIAKVNEDM 711
PYR+S LT LL++SLGGN+KT M+A +SPA +N +ETLSTLRYAN+A+ I N ++NED
Sbjct: 286 PYRDSKLTRLLQDSLGGNTKTLMVACLSPADNNYDETLSTLRYANRAKNIRNKPRINEDP 345
Query: 712 NAKLIRELKAEIAKLKAAQRNSRNIDPERYRLCRQ---EITSLRMKLHQQ---ERDMAEM 765
L+RE + EI KLKA + L RQ + + KL Q + D+
Sbjct: 346 KDALLREYQEEIKKLKAILTQQMSPSSLSALLSRQVPPDPVQVEEKLLPQPVIQHDVEAE 405
Query: 766 QRVWKEKFEQAEKRKLQETKELQKAGIMFQMD 797
+++ +E++E+ R + K Q++ + D
Sbjct: 406 KQLIREEYEERLARLKADYKAEQESRARLEED 437
>gi|46852174 kinesin family member 3A [Homo sapiens]
Length = 699
Score = 245 bits (626), Expect = 2e-64
Identities = 154/375 (41%), Positives = 221/375 (58%), Gaps = 24/375 (6%)
Query: 359 VTVAVRVRPFTKREK---IEKASQVVFMSGKEITVEHPDTKQVYNFIYDVSFWSFDECHP 415
V V VR RP +REK ++A V M G ITV D+ ++FD
Sbjct: 15 VKVVVRCRPLNEREKSMCYKQAVSVDEMRGT-ITVHKTDSSNE-----PPKTFTFDTVFG 68
Query: 416 HYASQTTVYEKLAAPLLERAFEGFNTCLFAYGQTGSGKSYTMMGFSEEP---GIIPRFCE 472
+ Q VY A P+++ EG+N +FAYGQTG+GK++TM G P GIIP
Sbjct: 69 PESKQLDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAIPELRGIIPNSFA 128
Query: 473 DLFSQVARKQTQEVSYHIEMSFFEVYNEKIHDLLVCKDENGQRKQPLRVREHPVYGPYVE 532
+F +A+ + + + + +S+ E+YNE++ DLL KD+ Q L V+E P G Y++
Sbjct: 129 HIFGHIAKAEG-DTRFLVRVSYLEIYNEEVRDLLG-KDQT----QRLEVKERPDVGVYIK 182
Query: 533 ALSMNIVSSYADIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTKTEFVEGEEHD 592
LS +V++ D+ + LG+K R+ AT MN+ SSRSH++FT+ + + + ++G H
Sbjct: 183 DLSAYVVNNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITI-ECSEKGIDGNMHV 241
Query: 593 HRITSRINLIDLAGSERCSTAHTNGDRLKEGVSINKSLLTLGKVISALSEQANQRSVFIP 652
+++L+DLAGSER + G RLKE IN SL TLG VISAL + +S +P
Sbjct: 242 RM--GKLHLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISAL---VDGKSTHVP 296
Query: 653 YRESVLTWLLKESLGGNSKTAMIATISPAASNIEETLSTLRYANQARLIVNIAKVNEDMN 712
YR S LT LL++SLGGNSKT M A I PA N +ET+STLRYAN+A+ I N A++NED
Sbjct: 297 YRNSKLTRLLQDSLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINEDPK 356
Query: 713 AKLIRELKAEIAKLK 727
L+R+ + EI +LK
Sbjct: 357 DALLRQFQKEIEELK 371
Score = 37.4 bits (85), Expect = 0.12
Identities = 31/145 (21%), Positives = 70/145 (48%), Gaps = 7/145 (4%)
Query: 923 DFEFAKNELLMAQRSQLEAEIKEAQLKAKEEMMQGIQIAKEMAQQELSSQKAAYESKIKA 982
+ E + +LL AQ+ ++ +++ K+ ++ G+ + + +QE K ES ++
Sbjct: 450 ELEKREKDLLKAQQEH-QSLLEKLSALEKKVIVGGVDLLAKAEEQE----KLLEESNMEL 504
Query: 983 LEAELREESQRKKMQEINNQKANHKIEELEKAKQHLEQEIYVNKKRLEMETLATKQALED 1042
E R E R++++E ++ + IEE + Q Q K++ +A K + D
Sbjct: 505 EERRKRAEQLRRELEEKEQERLD--IEEKYTSLQEEAQGKTKKLKKVWTMLMAAKSEMAD 562
Query: 1043 HSIRHARILEALETEKQKIAKEVQI 1067
H R +E L +++++E+++
Sbjct: 563 LQQEHQREIEGLLENIRQLSRELRL 587
>gi|41352705 kinesin family member 3C [Homo sapiens]
Length = 793
Score = 243 bits (620), Expect = 1e-63
Identities = 154/404 (38%), Positives = 232/404 (57%), Gaps = 60/404 (14%)
Query: 361 VAVRVRPFTKREKIEKASQVVFMSGK--EITVEHP-----DTKQVYNF--IYDVSFWSFD 411
V R RP +++E+ Q++ M K ++T+ +P + + + F +YD S
Sbjct: 13 VVARCRPLSRKEEAAGHEQILTMDVKLGQVTLRNPRAAPGELPKTFTFDAVYDAS----- 67
Query: 412 ECHPHYASQTTVYEKLAAPLLERAFEGFNTCLFAYGQTGSGKSYTMMGFSEEP---GIIP 468
+ Q +Y++ PL++ +GFN +FAYGQTG+GK+YTM G EP G+IP
Sbjct: 68 ------SKQADLYDETVRPLIDSVLQGFNGTVFAYGQTGTGKTYTMQGTWVEPELRGVIP 121
Query: 469 RFCEDLFSQVARKQTQEVSYHIEMSFFEVYNEKIHDLLVCKDENGQRKQPLRVREHPVYG 528
E +F+ ++R Q Q+ Y + S+ E+Y E+I DLL E G+R L ++E+P G
Sbjct: 122 NAFEHIFTHISRSQNQQ--YLVRASYLEIYQEEIRDLL--SKEPGKR---LELKENPETG 174
Query: 529 PYVEALSMNIVSSYADIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTKTEFVEG 588
Y++ LS + + +I+ + LGN+ RA +T MN+ SSRSH++F ++ + +G
Sbjct: 175 VYIKDLSSFVTKNVKEIEHVMNLGNQTRAVGSTHMNEVSSRSHAIF-IITVECSERGSDG 233
Query: 589 EEHDHRITSRINLIDLAGSERCSTAHTN------------------------GDRLKEGV 624
+ DH ++NL+DLAGSER + A N G+R KE
Sbjct: 234 Q--DHIRVGKLNLVDLAGSERQNKAGPNTAGGAATPSSGGGGGGGGSGGGAGGERPKEAS 291
Query: 625 SINKSLLTLGKVISALSEQANQRSVFIPYRESVLTWLLKESLGGNSKTAMIATISPAASN 684
IN SL LG VI+AL A RS IPYR+S LT LL++SLGGN+KT M+AT+ PA+ +
Sbjct: 292 KINLSLSALGNVIAAL---AGNRSTHIPYRDSKLTRLLQDSLGGNAKTIMVATLGPASHS 348
Query: 685 IEETLSTLRYANQARLIVNIAKVNEDMNAKLIRELKAEIAKLKA 728
+E+LSTLR+AN+A+ I N +VNED L+RE + EIA+LKA
Sbjct: 349 YDESLSTLRFANRAKNIKNKPRVNEDPKDTLLREFQEEIARLKA 392
Score = 39.3 bits (90), Expect = 0.032
Identities = 35/150 (23%), Positives = 75/150 (50%), Gaps = 22/150 (14%)
Query: 939 LEAEIKEAQLKAKEEMMQGIQIAKEMAQQELSSQKAAYESKI---------------KAL 983
L +E K+ L+ KE+M++ ++ ++ A + L+++ A ESK+ K L
Sbjct: 481 LVSEEKQKLLEEKEKMLEDLR-REQQATELLAAKYKAMESKLLIGGRNIMDHTNEQQKML 539
Query: 984 EAELREESQRKKMQEINNQKANHKIEE---LEKAKQHLEQEIYVNKKRLE---METLATK 1037
E + +E +++K+ + Q+ + EE L L+QE+ V K+L+ + A K
Sbjct: 540 ELKRQEIAEQKRREREMQQEMMLRDEETMELRGTYTSLQQEVEVKTKKLKKLYAKLQAVK 599
Query: 1038 QALEDHSIRHARILEALETEKQKIAKEVQI 1067
++D + R+ + LE + + +E+++
Sbjct: 600 AEIQDQHDEYIRVRQDLEEAQNEQTRELKL 629
Score = 34.3 bits (77), Expect = 1.0
Identities = 63/326 (19%), Positives = 138/326 (42%), Gaps = 55/326 (16%)
Query: 913 RDTPISEGPKDFEFAKNEL----LMAQRSQLEAEIKEAQLKAKEEMMQGIQIAKEMAQQE 968
+DT + E ++ K +L ++ +R + ++ ++ + A +G I +A++E
Sbjct: 376 KDTLLREFQEEIARLKAQLEKRGMLGKRPRRKSSRRKKAVSAPPGYPEGPVIEAWVAEEE 435
Query: 969 LSSQ------KAAYESKI-KALEAELREESQRKKMQE--------INNQKANHKIEELEK 1013
+ + ES + K +E L+E+ +R + ++ + +++ +EE EK
Sbjct: 436 DDNNNNHRPPQPILESALEKNMENYLQEQKERLEEEKAAIQDDRSLVSEEKQKLLEEKEK 495
Query: 1014 AKQHLEQE------IYVNKKRLEMETLATKQALEDHSIRHARILEALETEKQKIAKEVQI 1067
+ L +E + K +E + L + + DH+ ++LE E + + +
Sbjct: 496 MLEDLRREQQATELLAAKYKAMESKLLIGGRNIMDHTNEQQKMLELKRQEIAEQKRRERE 555
Query: 1068 LQQNRNNRD-KTFTVQTTWSSM---------KLSMMIQEANAISSKLKTY---YVFGRHD 1114
+QQ RD +T ++ T++S+ KL + + A+ ++++ Y+ R D
Sbjct: 556 MQQEMMLRDEETMELRGTYTSLQQEVEVKTKKLKKLYAKLQAVKAEIQDQHDEYIRVRQD 615
Query: 1115 ISDKSSSDTSIRVRNLKLGISTFWSLEKFESKLAAMKELYESNGSNRGEDAFCDPEDEW- 1173
+ + + T R LKL + E K M L+ C+ E++W
Sbjct: 616 LEEAQNEQT----RELKLKYLIIENFIPPEEKNKIMNRLFLD----------CE-EEQWK 660
Query: 1174 -EPDITDAPVSSLSRRRSRSLMKNRR 1198
+P + SS ++R S + +R
Sbjct: 661 FQPLVPAGVSSSQMKKRPTSAVGYKR 686
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 237 bits (605), Expect = 6e-62
Identities = 209/741 (28%), Positives = 356/741 (48%), Gaps = 80/741 (10%)
Query: 355 ENSQVTVAVRVRPFTKREK-IEKASQVVFMSGKEITVEHPDTKQVYNFIYDVSFWSFDEC 413
E V V VRVRP RE+ + + +QV + + + + +K ++FD
Sbjct: 3 EEGAVAVCVRVRPLNSREESLGETAQVYWKTDNNVIYQVDGSKS----------FNFDRV 52
Query: 414 HPHYASQTTVYEKLAAPLLERAFEGFNTCLFAYGQTGSGKSYTMMGFSEEPGIIPRFCED 473
+ VYE++AAP+++ A +G+N +FAYGQT SGK+YTMMG + G+IPR D
Sbjct: 53 FHGNETTKNVYEEIAAPIIDSAIQGYNGTIFAYGQTASGKTYTMMGSEDHLGVIPRAIHD 112
Query: 474 LFSQVARKQTQEVSYHIEMSFFEVYNEKIHDLLVCKDENGQRKQPLRVREHPVYGPYVEA 533
+F ++ K+ + + + +S+ E+YNE I DLL Q+ +PL +RE YV
Sbjct: 113 IFQKI--KKFPDREFLLRVSYMEIYNETITDLLC----GTQKMKPLIIREDVNRNVYVAD 166
Query: 534 LSMNIVSSYADIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTKTEFVEGEEHDH 593
L+ +V + W+ G K R T MN +SSRSH++F +++ + E
Sbjct: 167 LTEEVVYTSEMALKWITKGEKSRHYGETKMNQRSSRSHTIFRMILESREKGEPSNCEGSV 226
Query: 594 RITSRINLIDLAGSERCSTAHTNGDRLKEGVSINKSLLTLGKVISALSEQANQRSVFIPY 653
++ S +NL+DLAGSER + G RLKEG +IN+SL LG+VI LS+ Q FI Y
Sbjct: 227 KV-SHLNLVDLAGSERAAQTGAAGVRLKEGCNINRSLFILGQVIKKLSD--GQVGGFINY 283
Query: 654 RESVLTWLLKESLGGNSKTAMIATISPAASNIEETLSTLRYANQARLIVNIAKVNE-DMN 712
R+S LT +L+ SLGGN+KT +I TI+P + +ETL+ L++A+ A+ + N VNE +
Sbjct: 284 RDSKLTRILQNSLGGNAKTRIICTITPV--SFDETLTALQFASTAKYMKNTPYVNEVSTD 341
Query: 713 AKLIRELKAEIAKLKAAQRNSRNIDPERYRLCRQEITSLRMKLHQQERDMAEMQRVWKEK 772
L++ + EI LK Q +++ + + ++ L +E+D+ +Q+V EK
Sbjct: 342 EALLKRYRKEIMDLK-KQLEEVSLETRAQAMEKDQLAQL-----LEEKDL--LQKVQNEK 393
Query: 773 FEQAEKRKL--------QETKELQKAGIMFQMDNHLPNLVNLNEDPQLSEMLLYMIKEGT 824
E + + QE K +K + + + + + N N Q + + T
Sbjct: 394 IENLTRMLVTSSSLTLQQELKAKRKRRVTWCL-GKINKMKNSNYADQFN-----IPTNIT 447
Query: 825 TTVGKYKPNSSHDIQLSGVLIADDHCTIKNFGGTVSIIPVGEAKTYVNGKHI-LEITVLR 883
T K N +I S + + N T+S I A +N ++I E+ LR
Sbjct: 448 TKTHKLSINLLREIDES---VCSESDVFSNTLDTLSEIEWNPATKLLNQENIESELNSLR 504
Query: 884 HG-DRVILGGDHYFRFNHPVEVQKGKRPSGRDTPISEGPKDFEFAKNELLMAQRSQLEAE 942
D ++L + +E+ K K + D +FE + + Q QL E
Sbjct: 505 ADYDNLVLDYEQLRTEKEEMEL-KLKEKNDLD--------EFEALERKTKKDQEMQLIHE 555
Query: 943 IKEAQLKAKEEMMQGIQIAKEMAQQELSSQKAAYESKIKALEAELREESQRKKMQE-INN 1001
I + +++ ++ + + ELSS+ +E +E Q KK+QE I++
Sbjct: 556 ISNL-----KNLVKHAEVYNQDLENELSSK----------VELLREKEDQIKKLQEYIDS 600
Query: 1002 QKANHKIEELEKAKQHLEQEIYVNKKRLEMETLATKQALEDHSIRHARI-----LEALET 1056
QK + +L + + +E + + + ET+A E +R + ++ L T
Sbjct: 601 QKLENIKMDLSYSLESIEDPKQMKQTLFDAETVALDAKRESAFLRSENLELKEKMKELAT 660
Query: 1057 EKQKIAKEVQILQQNRNNRDK 1077
+++ ++Q+ Q + K
Sbjct: 661 TYKQMENDIQLYQSQLEAKKK 681
Score = 42.7 bits (99), Expect = 0.003
Identities = 88/446 (19%), Positives = 179/446 (40%), Gaps = 50/446 (11%)
Query: 651 IPYRESVLTWLLKESLGGNSKTAMIATISPAASNIEE--TLSTLRYANQARLIVNIAKVN 708
+ ++ES + LL+E G +K + T S S +E TL + + + + + N
Sbjct: 784 VVHKESRVQGLLEEI--GKTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYKM-VLEEN 840
Query: 709 EDMNAKLI------RELKAEIAKLKAAQRNSRNIDPERYRLCRQEITSLRMKLHQQERDM 762
E MN +++ ++ + + LK E+ R ++ + + Q E
Sbjct: 841 ERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQLENRD 900
Query: 763 AEMQRVWKEKFEQAEK------------------RKLQETKELQKAGIMFQMDNHLPNLV 804
+ +Q V +EK EK ++LQE+ ++++ Q+ + + + V
Sbjct: 901 STLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERD----QLKSDIHDTV 956
Query: 805 NLNEDPQLS-EMLLYMIKEGTTTVGKYKPNSSHDIQLSGVLIADDHCTIKNFGGTVSIIP 863
N+N D Q L +K+ T+ K S ++ + + + T F + I
Sbjct: 957 NMNIDTQEQLRNALESLKQHQETINTLKSKISEEVSRNLHMEENTGETKDEFQQKMVGI- 1015
Query: 864 VGEAKTYVNGKHILEITVLRHGDRVILGGDHYFRFNHPVEVQKGKRPSGRDTPISEGPKD 923
+ K + K+ +T + +I F +K + ++ I+E +
Sbjct: 1016 --DKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQ----EKNELQQMLESVIAEKEQL 1069
Query: 924 FEFAKNELLMAQRSQLEAEIKEAQLKAKEEMM---QGIQIAKEMAQQELSSQKAAYESKI 980
K + M +Q E + +LK ++E++ + I KE + A E K+
Sbjct: 1070 KTDLKENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKL 1129
Query: 981 KALEAELREESQRKKMQEINNQKANHKIEELEKAKQHLEQEIYVNKKRLEMETLATKQAL 1040
K +L+E+ Q+ + + KI E+E K L+ + + + +E E L Q L
Sbjct: 1130 KEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNK-ELTLEHMETERLELAQKL 1188
Query: 1041 EDHSIRHARILEALETEKQKIAKEVQ 1066
++ I T+++K+ KE+Q
Sbjct: 1189 NENYEEVKSI-----TKERKVLKELQ 1209
Score = 37.7 bits (86), Expect = 0.093
Identities = 82/470 (17%), Positives = 196/470 (41%), Gaps = 64/470 (13%)
Query: 635 KVISALSEQANQRSVFIPYRESVLTWLLKESLGGNSKTAMIATISPAASNIEETLSTLRY 694
K IS + E+ N+ F +R++ K+S + ++ M+ + + EE ++
Sbjct: 1538 KQISEVQEKVNELKQFKEHRKA------KDSALQSIESKMLELTNRLQESQEEIQIMIKE 1591
Query: 695 ANQARLIVNIAKVNEDMNAKLIRELKAEIAKLKAAQRNSRNIDPERYRLCRQEITSLRMK 754
+ + + ++ D + +E+ +AK+K +Q +E L+M
Sbjct: 1592 KEEMKRVQEALQIERDQLKENTKEI---VAKMKESQE--------------KEYQFLKMT 1634
Query: 755 -LHQQERDMAEMQRVWKEKFEQAEKRKLQ--ETKELQKAGIMFQMDNHLPNLVNLNEDPQ 811
+++ + M E++ + KE+FE +K L+ ET+ ++ I+ + + ++ +D +
Sbjct: 1635 AVNETQEKMCEIEHL-KEQFE-TQKLNLENIETENIRLTQILHENLEEMRSVTKERDDLR 1692
Query: 812 LSEMLLYM----IKEGTTTVGKYKPNSSHDIQLSGVLIADDHCTIKNFGGTVSIIP---V 864
E L + +KE ++++ + + + TI G VS
Sbjct: 1693 SVEETLKVERDQLKENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEIS 1752
Query: 865 GEAKTYVNGKHILEITVLRHGDRVILGGDHYFRFNHPVEVQKGKRPSGRDTPISEGPKDF 924
K + L+ L+ + + + H ++ +G S + +S KD
Sbjct: 1753 NMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGI-VSEKTDKLSNMQKDL 1811
Query: 925 EFAKNEL------LMAQRSQL---EAEIKEAQLKAKEEMMQGIQIAKEMAQQELSSQKAA 975
E + +L L A QL + ++ E Q K E Q+ K++ Q L+ K
Sbjct: 1812 ENSNAKLQEKIQELKANEHQLITLKKDVNETQKKVSEME----QLKKQIKDQSLTLSKLE 1867
Query: 976 YES---------KIKALEAELREESQRKKMQE---INNQKANHKIEELEKAKQHLEQEIY 1023
E+ ++ +++ ++E ++++E + + ++E + ++QE+
Sbjct: 1868 IENLNLAQKLHENLEEMKSVMKERDNLRRVEETLKLERDQLKESLQETKARDLEIQQELK 1927
Query: 1024 VNK--KRLEMETL-ATKQALEDHSIRHARILEALETEKQKIAKEVQILQQ 1070
+ + ET+ ++ + + +I+ + I + L+ K ++ K++Q LQ+
Sbjct: 1928 TARMLSKEHKETVDKLREKISEKTIQISDIQKDLDKSKDELQKKIQELQK 1977
Score = 35.4 bits (80), Expect = 0.46
Identities = 43/192 (22%), Positives = 85/192 (44%), Gaps = 20/192 (10%)
Query: 928 KNELLMAQRSQLEAEIKEAQLKAKEEMMQGIQIAKEMAQQELSS---QKAAYESKIKA-- 982
K +L L A++K+ ++ ++ + + K QQ L S +K ++ +K
Sbjct: 1018 KQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKENI 1077
Query: 983 -LEAELREE-----SQRKKMQEINNQKANHKIEELEKAKQHLEQEIYVNKKRLEMETLAT 1036
+ E +EE + KK QEI Q+ NH I++ + + ++ V +K E
Sbjct: 1078 EMTIENQEELRLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKE-----K 1132
Query: 1037 KQALEDHSIRHARILEALETEKQKIAKEVQILQQNRNNRDKTFTVQTTWS---SMKLSMM 1093
Q L++ + + E + +E QK E++ L+ N++ T T + KL+
Sbjct: 1133 SQQLQEKQQQLLNVQEEM-SEMQKKINEIENLKNELKNKELTLEHMETERLELAQKLNEN 1191
Query: 1094 IQEANAISSKLK 1105
+E +I+ + K
Sbjct: 1192 YEEVKSITKERK 1203
Score = 34.3 bits (77), Expect = 1.0
Identities = 39/192 (20%), Positives = 89/192 (46%), Gaps = 16/192 (8%)
Query: 969 LSSQKAAYESKIKALEAELREESQRKKMQEINNQKANHKIEELEKAKQHLEQEIYVNKKR 1028
LS + ++S + AL+ EL ++Q ++QE ++ ++ E+E+ K+ LE +
Sbjct: 850 LSKEAQKFDSSLGALKTELSYKTQ--ELQE-KTREVQERLNEMEQLKEQLE------NRD 900
Query: 1029 LEMETLATKQALEDHSIRHARILEALETEKQKIAKEVQILQQNRNNRDKTFTVQTTWSSM 1088
++T+ ++ L ++ + LE ++T Q+ Q+ + + RD+ + +M
Sbjct: 901 STLQTVEREKTLITEKLQ--QTLEEVKTLTQEKDDLKQLQESLQIERDQLKSDIHDTVNM 958
Query: 1089 KLSMMIQEANAISSKLKTYYVFGRHDISDKSSSDTSIRVRNLKLGISTFWSLEKFESKLA 1148
+ Q NA+ S + + + K S + S RNL + +T + ++F+ K+
Sbjct: 959 NIDTQEQLRNALESLKQHQETI--NTLKSKISEEVS---RNLHMEENTGETKDEFQQKMV 1013
Query: 1149 AMKELYESNGSN 1160
+ + + N
Sbjct: 1014 GIDKKQDLEAKN 1025
Score = 34.3 bits (77), Expect = 1.0
Identities = 38/185 (20%), Positives = 76/185 (41%), Gaps = 13/185 (7%)
Query: 923 DFEFAKNELLMAQRS--QLEAEIKEAQLKAKEEMMQGIQIAKEMA-----QQELSSQKAA 975
+ E KNEL + + +E E E K E + I KE Q+ +++
Sbjct: 1159 EIENLKNELKNKELTLEHMETERLELAQKLNENYEEVKSITKERKVLKELQKSFETERDH 1218
Query: 976 YESKIKALEAELREESQRKKMQEINNQKANHKIEELEKAKQHLEQEIYVNKKRLEMETLA 1035
I+ +EA + + K+ I+ ++ I+EL ++ +I +N + LE
Sbjct: 1219 LRGYIREIEATGLQTKEELKIAHIHLKEHQETIDELRRSVSEKTAQI-INTQDLEKSHTK 1277
Query: 1036 TKQ---ALEDHSIRHARILEALETEKQKIAKEVQILQQNRNNRDKTFTVQTTWSSMKLSM 1092
++ L + + E ET Q+ E+++L + +D T + ++L+
Sbjct: 1278 LQEEIPVLHEEQELLPNVKEVSET--QETMNELELLTEQSTTKDSTTLARIEMERLRLNE 1335
Query: 1093 MIQEA 1097
QE+
Sbjct: 1336 KFQES 1340
Score = 33.9 bits (76), Expect = 1.3
Identities = 95/427 (22%), Positives = 176/427 (41%), Gaps = 69/427 (16%)
Query: 669 NSKTAMIAT---ISPAASNIEETLSTLRYANQARLIVNIAKVNEDMNAKLIRELKAEIAK 725
+ KTA I + + + ++E + L + L+ N+ +V+E EL E +
Sbjct: 1259 SEKTAQIINTQDLEKSHTKLQEEIPVLH--EEQELLPNVKEVSETQETMNELELLTEQST 1316
Query: 726 LKAAQRNSRNIDPERYRL------CRQEITSLRMKLHQQERD-MAEMQRVWKEKFEQAEK 778
K + +R I+ ER RL ++EI SL +ERD + ++ + K +Q ++
Sbjct: 1317 TKDSTTLAR-IEMERLRLNEKFQESQEEIKSLT-----KERDNLKTIKEALEVKHDQLKE 1370
Query: 779 R------KLQETKELQKAGI-MFQMDNHLPNLVNLNEDPQLSEMLLYMIKEGTTTVGKYK 831
K+QE++ Q+ + M + DN +V+ E + + L I+ + K +
Sbjct: 1371 HIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSALLRIEIEMLGLSK-R 1429
Query: 832 PNSSHDIQLSGVLIADDHCTIKNFGGTVSIIPVGEAKTYVNGKHILEITVLRHGDRVILG 891
SHD S DD ++ V ++++ ++I EI V +H L
Sbjct: 1430 LQESHDEMKSVAKEKDDLQRLQE---------VLQSESDQLKENIKEI-VAKH-----LE 1474
Query: 892 GDHYFRFNHPVEVQKGKRPSGRDTPISEGPKDFEFAKNELLMAQRSQLEAEIK--EAQLK 949
+ + H K+ E NEL + S+ E EI + QL+
Sbjct: 1475 TEEELKVAHCCL------------------KEQEETINELRV-NLSEKETEISTIQKQLE 1515
Query: 950 AKEEMMQG-IQIAKEMAQQELSSQKAAYESKIKALEAELREESQRKKMQEINNQKANHKI 1008
A + +Q IQ E +Q Q + + K+ EL++ + +K ++ Q K+
Sbjct: 1516 AINDKLQNKIQEIYEKEEQFNIKQISEVQEKVN----ELKQFKEHRKAKDSALQSIESKM 1571
Query: 1009 EELEKAKQHLEQEIYVN-KKRLEMETLATKQALEDHSIRHARILEALETEKQKIAKEVQI 1067
EL Q ++EI + K++ EM+ + +E ++ E + K+ KE Q
Sbjct: 1572 LELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQLKE-NTKEIVAKMKESQEKEYQF 1630
Query: 1068 LQQNRNN 1074
L+ N
Sbjct: 1631 LKMTAVN 1637
Score = 32.3 bits (72), Expect = 3.9
Identities = 46/166 (27%), Positives = 78/166 (46%), Gaps = 18/166 (10%)
Query: 941 AEIKEAQLKAKEEMMQGIQIAKEMAQQELSSQKAAYESKIKALEAELREESQRKKMQEIN 1000
AE++E +LK K + +Q E QQ L+ Q+ E + K E E + + K +
Sbjct: 1123 AEVEE-KLKEKSQQLQ------EKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLE 1175
Query: 1001 NQKANHKIEELEKAKQHLEQEIYVNKKRLEMETLATKQALE-DHSIRHARILEA--LET- 1056
+ + ++E +K ++ E+ + K+R ++ L E DH + R +EA L+T
Sbjct: 1176 HME-TERLELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGLQTK 1234
Query: 1057 EKQKIA----KEVQ--ILQQNRNNRDKTFTVQTTWSSMKLSMMIQE 1096
E+ KIA KE Q I + R+ +KT + T K +QE
Sbjct: 1235 EELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQE 1280
>gi|38569484 kinesin family member 21A [Homo sapiens]
Length = 1661
Score = 237 bits (605), Expect = 6e-62
Identities = 213/787 (27%), Positives = 379/787 (48%), Gaps = 99/787 (12%)
Query: 355 ENSQVTVAVRVRPFTKREKIEKASQVVFMS-GKEITVEHPDTKQVYNFIYDVSFWSFDEC 413
+ S V VAVR+RP +EKIE ++ G+ D +++++D+
Sbjct: 6 DESSVRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVFLGKDKAFTFDYVFDID------- 58
Query: 414 HPHYASQTTVYEKLAAPLLERAFEGFNTCLFAYGQTGSGKSYTM-MGFS-----EEPGII 467
+ Q +Y + L+E FEG+N +FAYGQTG+GK+YTM GF EE GII
Sbjct: 59 ----SQQEQIYIQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNIVEEELGII 114
Query: 468 PRFCEDLFSQVARKQTQEVS-------YHIEMSFFEVYNEKIHDLL-VCKDENGQ-RKQP 518
R + LF + K+ + + + F E+YNE++ DL +D + + +K
Sbjct: 115 SRAVKHLFKSIEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDIDAKSKKSN 174
Query: 519 LRVREHPVYGPYVEALSMNIVSSYADIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVM 578
+R+ E G Y ++ V++ +++ L+LG R TA+T MN +SSRSH++FT+ +
Sbjct: 175 IRIHEDSTGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHV 234
Query: 579 TQTK----------------TEFVEGEEHDHRITSRINLIDLAGSERCSTAHTNGDRLKE 622
QT+ +E + E + +T++ + +DLAGSER G+R KE
Sbjct: 235 CQTRVCPQIDADNATDNKIISESAQMNEFE-TLTAKFHFVDLAGSERLKRTGATGERAKE 293
Query: 623 GVSINKSLLTLGKVISALSEQANQRSVFIPYRESVLTWLLKESLGGNSKTAMIATISPAA 682
G+SIN LL LG VISAL +++ +R+ +PYR+S LT LL++SLGGNS+T MIA +SP+
Sbjct: 294 GISINCGLLALGNVISALGDKS-KRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSD 352
Query: 683 SNIEETLSTLRYANQARLIVNIAKVNEDMNAKLIRELKAEIAKLKAA----QRNSRNIDP 738
+ ETL+TL+YAN+AR I N VN+D ++ I L++EI +L+ + R ID
Sbjct: 353 RDFMETLNTLKYANRARNIKNKVMVNQDRASQQINALRSEITRLQMELMEYKTGKRIIDE 412
Query: 739 E----------RYRLCRQEITSLRMKLH-QQERDMAEMQRVWKEKFEQAEKRKLQETKEL 787
E + + E +LR+++ QE A R+ + +QA L
Sbjct: 413 EGVESINDMFHENAMLQTENNNLRVRIKAMQETVDALRSRITQLVSDQA-------NHVL 465
Query: 788 QKAG-----IMFQMDNHLPNLVNLNEDPQLSEMLLYMIKEGTTTVGKYKPNSSHDIQLSG 842
+AG I + +++ + +L SE + +++ T P S S
Sbjct: 466 ARAGEGNEEISNMIHSYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSP 525
Query: 843 VLIADDHCTIKNFGGTVSIIPVGEAKTYVNGKHIL---EITVLRHGDRVILGGDHYFRFN 899
+++ D TI+ + + K K + + T + G R N
Sbjct: 526 TILSSDKETIEIIDLAKKDLEKLKRKEKRKKKSVAGKEDNTDTDQEKKEEKGVSE--REN 583
Query: 900 HPVEVQKGKRPSGRDTPISEGPKDFE-------FAKNELLMAQRSQLEAEIKEAQLKAKE 952
+ +EV++ + S + E ++ + +++ +++ +A++ A + +
Sbjct: 584 NELEVEESQEVSDHEDEEEEEEEEEDDIDGGESSDESDSESDEKANYQADL--ANITCEI 641
Query: 953 EMMQGIQIAKEMAQQELSSQKAAYESKIKALEAELRE-ESQRKKMQEINNQKANHKIEEL 1011
+ Q + E +Q+ L + K YE K+ L+ ++R+ + +R ++ + ++ E+
Sbjct: 642 AIKQKLIDELENSQKRLQTLKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKA 701
Query: 1012 EKAKQHLEQEIYVNKKRLEMETLATKQALEDHSIRHARILEALETEKQKIAKEVQILQQN 1071
+K + E+++ K L+ A K+ HAR+L+ + + K+++ LQQ+
Sbjct: 702 KKVRSEYEKKLQAMNKELQRLQAAQKE--------HARLLK----NQSQYEKQLKKLQQD 749
Query: 1072 RNNRDKT 1078
KT
Sbjct: 750 VMEMKKT 756
>gi|83716024 kinesin family member 21B [Homo sapiens]
Length = 1624
Score = 234 bits (598), Expect = 4e-61
Identities = 153/400 (38%), Positives = 223/400 (55%), Gaps = 43/400 (10%)
Query: 359 VTVAVRVRPFTKREKIEKASQVVFMS-GKEITVEHPDTKQVYNFIYDVSFWSFDECHPHY 417
V VAVR+RP +EKIE ++ G+ + D Y+F++D+ W
Sbjct: 9 VKVAVRIRPQLSKEKIEGCHICTSVTPGEPQVLLGKDKAFTYDFVFDLDTW--------- 59
Query: 418 ASQTTVYEKLAAPLLERAFEGFNTCLFAYGQTGSGKSYTM-MGFS-----EEPGIIPRFC 471
Q +Y + L+E FEG+N + AYGQTG+GK+YTM GF EE GIIPR
Sbjct: 60 --QEQIYSTCVSKLIEGCFEGYNATVLAYGQTGAGKTYTMGTGFDMATSEEEQGIIPRAI 117
Query: 472 EDLFSQVA----RKQTQEVS---YHIEMSFFEVYNEKIHDLL--VCKDENGQRKQPLRVR 522
LF +A R Q Q V+ + + F E+YNE+I DL + R+ +++
Sbjct: 118 AHLFGGIAERKRRAQEQGVAGPEFKVSAQFLELYNEEILDLFDSTRDPDTRHRRSNIKIH 177
Query: 523 EHPVYGPYVEALSMNIVSSYADIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTK 582
E G Y ++ ++ S ++ L+ G R TA+T MN +SSRSH++FT+ + Q +
Sbjct: 178 EDANGGIYTTGVTSRLIHSQEELIQCLKQGALSRTTASTQMNVQSSRSHAIFTIHLCQMR 237
Query: 583 --------TEFVEG-------EEHDHRITSRINLIDLAGSERCSTAHTNGDRLKEGVSIN 627
E V G +T++ + +DLAGSER G+R KEG+SIN
Sbjct: 238 MCTQPDLVNEAVTGLPDGTPPSSEYETLTAKFHFVDLAGSERLKRTGATGERAKEGISIN 297
Query: 628 KSLLTLGKVISALSEQANQRSVFIPYRESVLTWLLKESLGGNSKTAMIATISPAASNIEE 687
LL LG VISAL +Q+ ++ V +PYR+S LT LL++SLGGNS+T MIA +SP+ + E
Sbjct: 298 CGLLALGNVISALGDQS-KKVVHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFME 356
Query: 688 TLSTLRYANQARLIVNIAKVNEDMNAKLIRELKAEIAKLK 727
TL+TL+YAN+AR I N VN+D ++ I L+AEIA+L+
Sbjct: 357 TLNTLKYANRARNIKNKVVVNQDKTSQQISALRAEIARLQ 396
Score = 35.8 bits (81), Expect = 0.35
Identities = 76/380 (20%), Positives = 160/380 (42%), Gaps = 62/380 (16%)
Query: 714 KLIRELKAEIAKLKAAQRNSRNIDPERYRLCRQEITSLRMKLHQQERDMAEMQR----VW 769
K +RE+ ++ KL+AAQ+ E RL + + + +L + + ++AEM++ +
Sbjct: 712 KRLREMNRDLQKLQAAQK-------EHARLLKNQ-SRYERELKKLQAEVAEMKKAKVALM 763
Query: 770 KEKFEQAEKRKLQETKELQK-AGIMFQMDNHLPNLVNLNEDPQLSEMLLYMIKEGTTTVG 828
K+ E+ ++R+L ETK ++ A + + + L + EM+L + + +
Sbjct: 764 KQMREEQQRRRLVETKRNREIAQLKKEQRRQEFQIRALESQKRQQEMVLRRKTQEVSALR 823
Query: 829 KY-KPNSSHDIQLSGVLIADDHCTIKNFGGTVSIIPV-GEAKTYVNGKHILEITVLRHGD 886
+ KP S +G+ + + G VS EA++ +++R +
Sbjct: 824 RLAKPMSERVAGRAGL-----KPPMLDSGAEVSASTTSSEAESGARSVS----SIVRQWN 874
Query: 887 RVILGGDHYFRFNHPVEVQKGKRPSGRDTPISEGPKDFEFAKN-----------ELLMAQ 935
R I ++F +HP G RP+ + + F A +++M +
Sbjct: 875 RKI----NHFLGDHPAPTVNGTRPARKKFQKKGASQSFSKAARLKWQSLERRIIDIVMQR 930
Query: 936 RS--QLEAEIKEAQLKAKEEMMQGIQIAKEMAQQELSSQKAAYESKIKALEAELREESQR 993
+ LEA++ E +K +EE+ + Q+ L ++ +++ E L+E ++
Sbjct: 931 MTIVNLEADM-ERLIKKREELF--------LLQEALRRKRERLQAESPEEEKGLQELAEE 981
Query: 994 KKMQEINNQKANHKIEELEKAKQHLEQEIYVNKKRLEMETLATKQALEDHSIRHARIL-- 1051
++ N N I + + LE+ + E+++ T + S+ AR+L
Sbjct: 982 IEVLAANIDYINDGITDCQATIVQLEE------TKEELDSTDTSVVISSCSLAEARLLLD 1035
Query: 1052 ----EALETEKQKIAKEVQI 1067
+++ Q KE QI
Sbjct: 1036 NFLKASIDKGLQVAQKEAQI 1055
Score = 35.0 bits (79), Expect = 0.60
Identities = 27/114 (23%), Positives = 57/114 (50%), Gaps = 18/114 (15%)
Query: 945 EAQLKAKEEMMQGIQIAKEMAQQELSSQKAAYESKIKALEAE--------------LREE 990
E +L+ +Q +Q A++ + L +Q + YE ++K L+AE +REE
Sbjct: 711 EKRLREMNRDLQKLQAAQKEHARLLKNQ-SRYERELKKLQAEVAEMKKAKVALMKQMREE 769
Query: 991 SQRKKMQEINNQKANHKIEELEKAKQHLEQEIYVNKKRLEMETLATKQALEDHS 1044
QR+++ E K N +I +L+K ++ E +I + + + + ++ ++ S
Sbjct: 770 QQRRRLVE---TKRNREIAQLKKEQRRQEFQIRALESQKRQQEMVLRRKTQEVS 820
>gi|9910266 kinesin family member 15 [Homo sapiens]
Length = 1388
Score = 228 bits (580), Expect = 5e-59
Identities = 206/679 (30%), Positives = 330/679 (48%), Gaps = 87/679 (12%)
Query: 355 ENSQVTVAVRVRPFTKREKIEKASQVVFMSGKEITV----EHPDTKQVYNFIYDVSFWSF 410
E + V VR+RP +R Q + +S T +P+ K ++F
Sbjct: 23 EGDAIKVFVRIRPPAERSGSADGEQNLCLSVLSSTSLRLHSNPEPKT----------FTF 72
Query: 411 DECHPHYASQTTVYEKLAAPLLERAFEGFNTCLFAYGQTGSGKSYTMMGFSEEP------ 464
D +Q +V+ +A ++E G+N +FAYGQTGSGK++TMMG SE
Sbjct: 73 DHVADVDTTQESVFATVAKSIVESCMSGYNGTIFAYGQTGSGKTFTMMGPSESDNFSHNL 132
Query: 465 -GIIPRFCEDLFSQVARKQTQE---VSYHIEMSFFEVYNEKIHDLLVCKDENGQRKQPLR 520
G+IPR E LFS + R++ + S+ + SF E+YNE+I+DLL L
Sbjct: 133 RGVIPRSFEYLFSLIDREKEKAGAGKSFLCKCSFIEIYNEQIYDLL------DSASAGLY 186
Query: 521 VREHPVYGPYVEALSMNIVSSYADIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQ 580
+REH G +V +V+S A+ L G + R A+T MN +SSRSH+VFT+
Sbjct: 187 LREHIKKGVFVVGAVEQVVTSAAEAYQVLSGGWRNRRVASTSMNRESSRSHAVFTIT--- 243
Query: 581 TKTEFVEGEEHDHRI----TSRINLIDLAGSERCSTAHTNGDRLKEGVSINKSLLTLGKV 636
+E E + I TS +NL+DLAGSER H G RLKE +IN+SL LG+V
Sbjct: 244 -----IESMEKSNEIVNIRTSLLNLVDLAGSERQKDTHAEGMRLKEAGNINRSLSCLGQV 298
Query: 637 ISALSEQANQRSVFIPYRESVLTWLLKESLGGNSKTAMIATISPAASNIEETLSTLRYAN 696
I+AL + N + + YR+S LT+LL++SLGGN+KTA+IA + P + ETLSTL +A
Sbjct: 299 ITALVDVGNGKQRHVCYRDSKLTFLLRDSLGGNAKTAIIANVHPGSRCFGETLSTLNFAQ 358
Query: 697 QARLIVNIAKVNEDMNAKLIRELKAEIAKLK--AAQRNSRNIDPERYRLCRQEITSLRMK 754
+A+LI N A VNED + +L+AE+ +LK A+ S PE + L R + + M+
Sbjct: 359 RAKLIKNKAVVNEDTQGN-VSQLQAEVKRLKEQLAELASGQTPPESF-LTRDKKKTNYME 416
Query: 755 LHQQE----RDMAEMQRVWKEKFEQAEKRKLQETKELQKAGIMFQM-DNHLPNLVNLNED 809
Q+ + + ++ EK Q E L++ K +Q ++ + ++ + L L+++
Sbjct: 417 YFQEAMLFFKKSEQEKKSLIEKVTQLEDLTLKKEKFIQSNKMIVKFREDQIIRLEKLHKE 476
Query: 810 PQ---LSEMLLYMIKEGTTTVGKYKPNSSHDIQLSGVLIADDHCTIKNFGGTVSIIPVG- 865
+ L E ++ E + + H +++ + ++H + + PV
Sbjct: 477 SRGGFLPEEQDRLLSELRNEIQTLREQIEHHPRVAKYAM-ENHSLREENRRLRLLEPVKR 535
Query: 866 ----EAKTYVN-GKHILEITVLRHGDRVILGGDHYFRFNHPVEVQKGKRPSGRDTPISEG 920
+A+T K EI+ + D+ Q+G P + P
Sbjct: 536 AQEMDAQTIAKLEKAFSEISGMEKSDK----------------NQQGFSPKAQKEPCL-- 577
Query: 921 PKDFEFAKNELLMAQRSQLEAEIKEAQLKAKE--EMMQGIQIAKEMAQQELSSQKAAYES 978
FA E L AQ Q++ E+ ++ + +E E+ + Q+ E Q L E+
Sbjct: 578 -----FANTEKLKAQLLQIQTELNNSKQEYEEFKELTRKRQLELESELQSLQKANLNLEN 632
Query: 979 KIKALEAELREE-SQRKKM 996
++A +A R+E SQ K+
Sbjct: 633 LLEATKACKRQEVSQLNKI 651
Score = 50.4 bits (119), Expect = 1e-05
Identities = 87/435 (20%), Positives = 177/435 (40%), Gaps = 46/435 (10%)
Query: 691 TLRYANQARLIVNIAKVNEDMNAKLIRELK---AEIAKLKAAQRNSRNIDPERYR--LCR 745
+LR N+ ++ K ++M+A+ I +L+ +EI+ ++ + +N + P+ +
Sbjct: 519 SLREENRRLRLLEPVKRAQEMDAQTIAKLEKAFSEISGMEKSDKNQQGFSPKAQKEPCLF 578
Query: 746 QEITSLRMKLHQQERDMAEMQRVWKEKFEQAEKRKLQ---ETKELQKAGIMFQMDNHLPN 802
L+ +L Q + ++ ++ ++E E KR+L+ E + LQKA + +
Sbjct: 579 ANTEKLKAQLLQIQTELNNSKQEYEEFKELTRKRQLELESELQSLQKANLNLENLLEATK 638
Query: 803 LVNLNEDPQLSEMLLYMIKEGTTTVGKYK------PNSSHDIQLSGVLIADDHCTIKNFG 856
E QL+++ +K TT Y+ P S ++ G L + + N
Sbjct: 639 ACKRQEVSQLNKIHAETLKIITTPTKAYQLHSRPVPKLSPEMGSFGSLYTQNSSILDNDI 698
Query: 857 GTVSIIP-VGEAKTYVNGKHILEITVLRHGDRVILGGDHYFRFNHPVEVQKGKRPSGRDT 915
+ P + E + + + + L + + V K + S +
Sbjct: 699 LNEPVPPEMNEQAFEAISEELRTVQEQMSALQAKLDEEEHKNLKLQQHVDKLEHHSTQMQ 758
Query: 916 PISEGPKDFEFAKNELLMAQRSQLEAEIKEAQLKAK--EEMMQGIQIAKEMAQQELSSQK 973
+ + + E L++Q + LE +++E Q K + + +++ A +ELSS K
Sbjct: 759 ELFSSERIDWTKQQEELLSQLNVLEKQLQETQTKNDFLKSEVHDLRVVLHSADKELSSVK 818
Query: 974 AAYESKIKALEAELREESQRKKMQEINNQKANHKIEELEKAKQHLEQEIYVNKKRLEME- 1032
Y S + N +K +K+ E +H+ ++ ++ RLE E
Sbjct: 819 LEYSS------------------FKTNQEKEFNKLSE-----RHMHVQLQLDNLRLENEK 855
Query: 1033 TLATKQALEDHSIRHARI----LEALETEKQKIAKEVQILQQNRNNRDKTFTVQTTWSSM 1088
L +K L+D I ++ L Q KE + L+ + NN + + ++
Sbjct: 856 LLESKACLQDSYDNLQEIMKFEIDQLSRNLQNFKKENETLKSDLNNLMELLEAEKERNN- 914
Query: 1089 KLSMMIQEANAISSK 1103
KLS+ +E SSK
Sbjct: 915 KLSLQFEEDKENSSK 929
Score = 34.7 bits (78), Expect = 0.79
Identities = 33/138 (23%), Positives = 69/138 (50%), Gaps = 14/138 (10%)
Query: 942 EIKEAQLKAKEEMMQGIQIAKEMAQQELSS---QKAAYESKIKAL----EAELREESQRK 994
++K Q ++ +E + +I +EM + + Q A Y +++ L E E + + K
Sbjct: 1241 QLKNEQEESIKERLAKSKIVEEMLKMKADLEEVQSALYNKEMECLRMTDEVERTQTLESK 1300
Query: 995 KMQEINNQKANHKIEELEKAKQHLEQEIYVNKKRLEMETLATKQA-LEDHSIRHARI--L 1051
QE ++ K+EE+ + ++ QE+ + +K ++E LA + L H H +I +
Sbjct: 1301 AFQE--KEQLRSKLEEMYEERERTSQEMEMLRK--QVECLAEENGKLVGHQNLHQKIQYV 1356
Query: 1052 EALETEKQKIAKEVQILQ 1069
L+ E ++A+E + L+
Sbjct: 1357 VRLKKENVRLAEETEKLR 1374
Score = 32.7 bits (73), Expect = 3.0
Identities = 31/129 (24%), Positives = 60/129 (46%), Gaps = 10/129 (7%)
Query: 944 KEAQLKAKEEMMQGIQIAKEMAQ-QELSSQKAAYESKIKALEAELREESQRKKMQEINNQ 1002
+EA L K+ + + +++ Q ++L+ +K + K + + RE+ + +
Sbjct: 419 QEAMLFFKKSEQEKKSLIEKVTQLEDLTLKKEKFIQSNKMI-VKFREDQIIRLEKLHKES 477
Query: 1003 KANHKIEELEKAKQHLEQEIYVNKKRLEMETLATKQALEDHSI----RHARILE----AL 1054
+ EE ++ L EI ++++E K A+E+HS+ R R+LE A
Sbjct: 478 RGGFLPEEQDRLLSELRNEIQTLREQIEHHPRVAKYAMENHSLREENRRLRLLEPVKRAQ 537
Query: 1055 ETEKQKIAK 1063
E + Q IAK
Sbjct: 538 EMDAQTIAK 546
>gi|13699824 kinesin family member 11 [Homo sapiens]
Length = 1056
Score = 225 bits (573), Expect = 3e-58
Identities = 166/477 (34%), Positives = 260/477 (54%), Gaps = 52/477 (10%)
Query: 344 NTSAGKDPLKVENSQVTVAVRVRPFTKREKIEKASQVVFMSG--KEITVEH---PDTKQV 398
N+SA K K +N QV V R RPF E+ A +V KE++V D
Sbjct: 6 NSSAKKKEEKGKNIQVVV--RCRPFNLAERKASAHSIVECDPVRKEVSVRTGGLADKSSR 63
Query: 399 YNFIYDVSFWSFDECHPHYASQTTVYEKLAAPLLERAFEGFNTCLFAYGQTGSGKSYTMM 458
+ +D+ F + + Q VY + P+L+ G+N +FAYGQTG+GK++TM
Sbjct: 64 KTYTFDMVFGASTK-------QIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTME 116
Query: 459 G---------FSEEP--GIIPRFCEDLFSQVARKQTQEVSYHIEMSFFEVYNEKIHDLLV 507
G + E+P GIIPR +F ++ T+ + +++S E+YNE++ DLL
Sbjct: 117 GERSPNEEYTWEEDPLAGIIPRTLHQIFEKLTDNGTE---FSVKVSLLEIYNEELFDLLN 173
Query: 508 CKDENGQRKQPLRVREHPVYGPYVEALSMNIVSSYADIQSWLELGNKQRATAATGMNDKS 567
+ +R Q + G ++ L V + ++ LE G +R TAAT MN S
Sbjct: 174 PSSDVSERLQMFDDPRNK-RGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYS 232
Query: 568 SRSHSVFTLVMTQTKTEFVEGEEHDHRITSRINLIDLAGSERCSTAHTNGDRLKEGVSIN 627
SRSHSVF++ + +T ++GEE ++NL+DLAGSE + R +E +IN
Sbjct: 233 SRSHSVFSVTIHMKETT-IDGEELVK--IGKLNLVDLAGSENIGRSGAVDKRAREAGNIN 289
Query: 628 KSLLTLGKVISALSEQANQRSVFIPYRESVLTWLLKESLGGNSKTAMIATISPAASNIEE 687
+SLLTLG+VI+AL E R+ +PYRES LT +L++SLGG ++T++IATISPA+ N+EE
Sbjct: 290 QSLLTLGRVITALVE----RTPHVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEE 345
Query: 688 TLSTLRYANQARLIVNIAKVNEDMNAK-LIRELKAEIAKLK-----AAQRNSRNIDPERY 741
TLSTL YA++A+ I+N +VN+ + K LI+E EI +LK A ++N I E +
Sbjct: 346 TLSTLEYAHRAKNILNKPEVNQKLTKKALIKEYTEEIERLKRDLAAAREKNGVYISEENF 405
Query: 742 RLC-------RQEITSLRMKLHQQERDMAEMQRVW---KEKFEQAEKRKLQETKELQ 788
R+ ++I L K+ E ++ + ++ K + +Q + +T+EL+
Sbjct: 406 RVMSGKLTVQEEQIVELIEKIGAVEEELNRVTELFMDNKNELDQCKSDLQNKTQELE 462
>gi|30794488 kinesin family member 27 [Homo sapiens]
Length = 1401
Score = 221 bits (563), Expect = 5e-57
Identities = 144/423 (34%), Positives = 228/423 (53%), Gaps = 28/423 (6%)
Query: 354 VENSQVTVAVRVRPFTKREKIEKASQVVFMSGKEITVEHPDTKQVYNFIYDVSFWSFDEC 413
+E V VAVR+RP +E + V + P+++QV I ++FD
Sbjct: 1 MEEIPVKVAVRIRPLLCKEALHNHQVCVRVI--------PNSQQV--IIGRDRVFTFDFV 50
Query: 414 HPHYASQTTVYEKLAAPLLERAFEGFNTCLFAYGQTGSGKSYTMMG------FSEEPGII 467
++Q VY PL+ EG+N +FAYGQTGSGK+YT+ G + GII
Sbjct: 51 FGKNSTQDEVYNTCIKPLVLSLIEGYNATVFAYGQTGSGKTYTIGGGHIASVVEGQKGII 110
Query: 468 PRFCEDLFSQVARKQTQEVSYHIEMSFFEVYNEKIHDLLVCKDENGQRKQPLRVREHPVY 527
PR +++F ++ + + +++++S+ EVY E + DLL E + L +RE
Sbjct: 111 PRAIQEIFQSISEHPS--IDFNVKVSYIEVYKEDLRDLL----ELETSMKDLHIREDEKG 164
Query: 528 GPYVEALSMNIVSSYADIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTKTEFVE 587
+ V S ++ S LE+GN R T T MN+ SSRSH++FT+ + Q
Sbjct: 165 NTVIVGAKECHVESAGEVMSLLEMGNAARHTGTTQMNEHSSRSHAIFTISICQVHKNMEA 224
Query: 588 GEEHD----HRITSRINLIDLAGSERCSTAHTNGDRLKEGVSINKSLLTLGKVISALSEQ 643
E+ I S+ + +DLAGSER + G+R KE + IN LL LG VISAL +
Sbjct: 225 AEDGSWYSPRHIVSKFHFVDLAGSERVTKTGNTGERFKESIQINSGLLALGNVISALGDP 284
Query: 644 ANQRSVFIPYRESVLTWLLKESLGGNSKTAMIATISPAASNIEETLSTLRYANQARLIVN 703
++S IPYR++ +T LLK+SLGG++KT MI +SP++SN +E+L++L+YAN+AR I N
Sbjct: 285 -RRKSSHIPYRDAKITRLLKDSLGGSAKTVMITCVSPSSSNFDESLNSLKYANRARNIRN 343
Query: 704 IAKVNEDMNAKLIRELKAEIAKLKAAQRNSRNIDPERYRLCRQEITSLRMKLHQQERDMA 763
VN + I E++ EI L+ A ++ + + ++ R+ ++H E +A
Sbjct: 344 KPTVNFSPESDRIDEMEFEIKLLREALQSQQAGVSQTTQINREGSPDTN-RIHSLEEQVA 402
Query: 764 EMQ 766
++Q
Sbjct: 403 QLQ 405
Score = 45.8 bits (107), Expect = 3e-04
Identities = 47/191 (24%), Positives = 90/191 (47%), Gaps = 22/191 (11%)
Query: 935 QRSQLEAEIKEAQLKAKEEMMQGIQI------AKEMAQQELSSQKAAYESKIKALEAELR 988
+R QL+A IK Q K KE ++ Q A+++ L +K ++ S L+
Sbjct: 865 KRKQLDAVIKRDQQKIKEIQLKTGQEEGLKPKAEDLDACNLKRRKGSFGSI-----DHLQ 919
Query: 989 EESQRKKMQEINNQKANHKIEELEKAKQHLEQ-EIYVNKKRLEMETLATKQALEDHSIRH 1047
+ ++KK + +K ++ +ELE+ + L++ E V+KK L K LE+ +R
Sbjct: 920 KLDEQKKWLDEEVEKVLNQRQELEELEADLKKREAIVSKKEA---LLQEKSHLENKKLRS 976
Query: 1048 ARILEALETEKQKIAKEVQILQQNRNNRDKTFTVQTTWSSMKLSMMIQEANAISSKLKTY 1107
+ +AL T+ KI+ + +L+Q + ++ T K+S ++ + K K
Sbjct: 977 S---QALNTDSLKISTRLNLLEQELSEKNVQLQTSTAEEKTKISEQVE----VLQKEKDQ 1029
Query: 1108 YVFGRHDISDK 1118
RH++ +K
Sbjct: 1030 LQKRRHNVDEK 1040
Score = 32.3 bits (72), Expect = 3.9
Identities = 33/145 (22%), Positives = 63/145 (43%), Gaps = 26/145 (17%)
Query: 923 DFEFAKNELLMAQRSQLEAEIKEAQLKAKEEMMQGIQIAKEMAQQELSSQKAAYESKIKA 982
D E AK EL+ Q+ E E K+ A K Q+E + A + +++
Sbjct: 767 DAEQAKVELIETQKQLQELENKDLSDVAM----------KVKLQKEFRKKMDAAKLRVQV 816
Query: 983 LEAELREESQRKKMQEINNQKANHKIEELEKAKQHLEQEIYVNKKRLEMETLATKQALED 1042
L+ + ++ + + N ++AN ELE++ H++ + +++L E KQ
Sbjct: 817 LQKKQQDSKKLASLSIQNEKRAN----ELEQSVDHMKYQKIQLQRKLREENEKRKQ---- 868
Query: 1043 HSIRHARILEALETEKQKIAKEVQI 1067
L+A+ Q+ KE+Q+
Sbjct: 869 --------LDAVIKRDQQKIKEIQL 885
>gi|122937289 kinesin family member 18B [Homo sapiens]
Length = 855
Score = 216 bits (551), Expect = 1e-55
Identities = 145/397 (36%), Positives = 225/397 (56%), Gaps = 34/397 (8%)
Query: 352 LKVENSQVTVAVRVRPFTKREKIEKASQVVFMSGKEITVEHPDTKQ-------------- 397
+ VE+S + V VRVRP T RE + VV + + + V +P+
Sbjct: 1 MAVEDSTLQVVVRVRPPTPRELDSQRRPVVQVVDERVLVFNPEEPDGGFPGLKWGGTHDG 60
Query: 398 VYNFIYDVSFWSFDECHPHYASQTTVYEKLAAPLLERAFEGFNTCLFAYGQTGSGKSYTM 457
D++F FD A+Q V++ +L+ +G+N +FAYG TG+GK++TM
Sbjct: 61 PKKKGKDLTF-VFDRVFGEAATQQDVFQHTTHSVLDSFLQGYNCSVFAYGATGAGKTHTM 119
Query: 458 MGFSEEPGIIPRFCEDLFSQVARKQTQEVSYHIEMSFFEVYNEKIHDLLVCKDENGQRKQ 517
+G +PGI+ +L+ ++ +Q QE + + +S+ EVYNE+IHDLL + K
Sbjct: 120 LGREGDPGIMYLTTVELYRRLEARQ-QEKHFEVLISYQEVYNEQIHDLL-------EPKG 171
Query: 518 PLRVREHPVYGPYVEALSMNIVSSYADIQSWLELGNKQRATAATGMNDKSSRSHSVFTLV 577
PL +RE P G V+ LS + +S + L GN+ R T N SSRSH++F +
Sbjct: 172 PLAIREDPDKGVVVQGLSFHQPASAEQLLEILTRGNRNRTQHPTDANATSSRSHAIFQIF 231
Query: 578 MTQTKTEFVEGEEHDHRITSRINLIDLAGSERCSTAHTNGDRLKEGVSINKSLLTLGKVI 637
+ Q + V G ++ ++++LIDLAGSER S+ H G+RL+EG +IN+SLL L V+
Sbjct: 232 VKQQ--DRVPGLTQAVQV-AKMSLIDLAGSERASSTHAKGERLREGANINRSLLALINVL 288
Query: 638 SALSEQANQRSVFIPYRESVLTWLLKESLGGNSKTAMIATISPAASNIEETLSTLRYANQ 697
+AL++ A R +PYR+S LT LLK+SLGGN +T MIA ISP++ E+T +TL+YA++
Sbjct: 289 NALAD-AKGRKTHVPYRDSKLTRLLKDSLGGNCRTVMIAAISPSSLTYEDTYNTLKYADR 347
Query: 698 ARLIVNIAKVNE-------DMNAKLIRELKAEIAKLK 727
A+ I K N A + ++L+AE+A L+
Sbjct: 348 AKEIRLSLKSNVTSLDCHISQYATICQQLQAEVAALR 384
>gi|4758650 kinesin family member 5C [Homo sapiens]
Length = 957
Score = 214 bits (544), Expect = 7e-55
Identities = 206/748 (27%), Positives = 339/748 (45%), Gaps = 143/748 (19%)
Query: 410 FDECHPHYASQTTVYEKLAAPLLERAFEGFNTCLFAYGQTGSGKSYTMMGFSEEP---GI 466
FD P +Q VY A +++ EG+N +FAYGQT SGK++TM G +P GI
Sbjct: 49 FDRVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGI 108
Query: 467 IPRFCEDLFSQVARKQTQEVSYHIEMSFFEVYNEKIHDLLVCKDENGQRKQPLRVREHPV 526
IPR D+F + + + +HI++S+FE+Y +KI DLL N L V E
Sbjct: 109 IPRIAHDIFDHIY-SMDENLEFHIKVSYFEIYLDKIRDLLDVSKTN------LAVHEDKN 161
Query: 527 YGPYVEALSMNIVSSYADIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTKTEFV 586
PYV+ + VSS ++ ++ G R A T MN+ SSRSHS+F + + Q
Sbjct: 162 RVPYVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQ------ 215
Query: 587 EGEEHDHRITSRINLIDLAGSERCSTAHTNGDRLKEGVSINKSLLTLGKVISALSEQANQ 646
E E + +++ ++ L+DLAGSE+ S G L E +INKSL LG VISAL+E
Sbjct: 216 ENVETEKKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKT 275
Query: 647 RSVFIPYRESVLTWLLKESLGGNSKTAMIATISPAASNIEETLSTLRYANQARLIVNIAK 706
+PYR+S +T +L++SLGGN +T ++ SP+ N ET STL + +A+ I N
Sbjct: 276 H---VPYRDSKMTRILQDSLGGNCRTTIVICCSPSVFNEAETKSTLMFGQRAKTIKNTVS 332
Query: 707 VNEDMNAK------------------LIRELKAEIAKLKAAQ----------RNSRNIDP 738
VN ++ A+ +I+ L+ E+ + + + ++ +N++P
Sbjct: 333 VNLELTAEEWKKKYEKEKEKNKTLKNVIQHLEMELNRWRNGEAVPEDEQISAKDQKNLEP 392
Query: 739 ----------------------ERY-----RLCRQ---------EITSLRMKLHQQERDM 762
E+Y L RQ + + L KL QQ D
Sbjct: 393 CDNTPIIDNIAPVVAGISTEEKEKYDEEISSLYRQLDDKDDEINQQSQLAEKLKQQMLDQ 452
Query: 763 AEMQRVWKEKFE--QAEKRKLQETKELQKAGIMFQMDNHLPNLVNLNEDPQ-------LS 813
E+ + +E Q E +LQ E K + + VN ++ Q +
Sbjct: 453 DELLASTRRDYEKIQEELTRLQIENEAAKDEVKEVLQALEELAVNYDQKSQEVEDKTRAN 512
Query: 814 EMLLYMIKEGTTT-------VGKYKPNSSHDIQLSGVLIADDHCTIKNFGGTVSIIPVGE 866
E L + + TTT + + + S+H + + ++ + +K+ G II +
Sbjct: 513 EQLTDELAQKTTTLTTTQRELSQLQELSNHQKKRATEIL---NLLLKDLGEIGGIIGTND 569
Query: 867 AKTY--VNGKHILEITVLRHGDRVILGGDHYFRFNHPVEVQKGKRPSGRDTPISEGPKDF 924
KT VNG E T+ R + + N +++ + S R SE
Sbjct: 570 VKTLADVNGVIEEEFTMARLYISK-MKSEVKSLVNRSKQLESAQMDSNRKMNASER---- 624
Query: 925 EFAKNELLMAQRSQLEAEIKEAQLKAKEEMMQGIQIAKEMAQQELSSQKAAYESKIKALE 984
E A +LL++Q EA++K+ + MQ + E K + LE
Sbjct: 625 ELAACQLLISQH--------EAKIKSLTDYMQNM------------------EQKRRQLE 658
Query: 985 AELREESQRKKMQEINNQKANHKIEELEKAKQHLE--QEIYVNKKRLEMETLATKQALED 1042
++S +++ ++ Q+ H++ +K K+HL Q+ KK LE + + ++A
Sbjct: 659 ES--QDSLSEELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEMKKALEQQMESHREA--- 713
Query: 1043 HSIRHARILEALETEKQKIAKEVQILQQ 1070
H + +R+ + +E EKQKI E++ L Q
Sbjct: 714 HQKQLSRLRDEIE-EKQKIIDEIRDLNQ 740
>gi|148612831 kinesin family member 18A [Homo sapiens]
Length = 898
Score = 213 bits (541), Expect = 2e-54
Identities = 156/447 (34%), Positives = 237/447 (53%), Gaps = 40/447 (8%)
Query: 361 VAVRVRPFTKREKIEKASQVVFMSGKEITVEHPDTKQVYNFI--------------YDVS 406
V VRVRP +EK +VV + K I V P ++V F D+
Sbjct: 14 VVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTTNQNVIKKQNKDLK 73
Query: 407 FWSFDECHPHYASQTTVYEKLAAPLLERAFEGFNTCLFAYGQTGSGKSYTMMGFSEEPGI 466
F FD ++Q+ V+E P+L G+N + AYG TG+GK++TM+G ++EPG+
Sbjct: 74 F-VFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTMLGSADEPGV 132
Query: 467 IPRFCEDLFSQVARKQTQEVSYHIEMSFFEVYNEKIHDLLVCKDENGQRKQPLRVREHPV 526
+ L+ + + +++ +S+ EVYNE+I DLLV PL VRE
Sbjct: 133 MYLTMLHLYKCMDEIKEEKIC-STAVSYLEVYNEQIRDLLV-------NSGPLAVREDTQ 184
Query: 527 YGPYVEALSMNIVSSYADIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQT-KTEF 585
G V L+++ S +I L+ GNK R T MN SSRSH+VF + + Q KT
Sbjct: 185 KGVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQQDKTAS 244
Query: 586 VEGEEHDHRITSRINLIDLAGSERCSTAHTNGDRLKEGVSINKSLLTLGKVISALSEQAN 645
+ + RI ++++LIDLAGSER ST+ G R EG +IN+SLL LG VI+AL++ +
Sbjct: 245 IN---QNVRI-AKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINALAD-SK 299
Query: 646 QRSVFIPYRESVLTWLLKESLGGNSKTAMIATISPAASNIEETLSTLRYANQAR-----L 700
+++ IPYR S LT LLK+SLGGN +T MIA +SP++ ++T +TL+YAN+A+ L
Sbjct: 300 RKNQHIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKDIKSSL 359
Query: 701 IVNIAKVNEDMN--AKLIRELKAEIAKLKAAQRNSRNIDPERYRLCRQEITSLRMKLHQQ 758
N+ VN + K+ E KAEI LK + E+ + + M + Q
Sbjct: 360 KSNVLNVNNHITQYVKICNEQKAEILLLKEKLKAYE----EQKAFTNENDQAKLMISNPQ 415
Query: 759 ERDMAEMQRVWKEKFEQAEKRKLQETK 785
E+++ Q + F+ E+ + + K
Sbjct: 416 EKEIERFQEILNCLFQNREEIRQEYLK 442
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.128 0.354
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 56,080,450
Number of Sequences: 37866
Number of extensions: 2433582
Number of successful extensions: 12586
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 238
Number of HSP's successfully gapped in prelim test: 672
Number of HSP's that attempted gapping in prelim test: 8188
Number of HSP's gapped (non-prelim): 3941
length of query: 1648
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1532
effective length of database: 13,855,062
effective search space: 21225954984
effective search space used: 21225954984
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.