BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|7661734 mRNA decapping enzyme [Homo sapiens] (337 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|7661734 mRNA decapping enzyme [Homo sapiens] 681 0.0 gi|28329436 aprataxin isoform a [Homo sapiens] 38 0.011 gi|28329433 aprataxin isoform c [Homo sapiens] 38 0.011 gi|28329427 aprataxin isoform d [Homo sapiens] 38 0.011 gi|28329430 aprataxin isoform b [Homo sapiens] 38 0.011 gi|8923156 aprataxin isoform d [Homo sapiens] 38 0.011 gi|24415404 MDN1, midasin homolog [Homo sapiens] 37 0.025 gi|224994173 roundabout 1 isoform d [Homo sapiens] 34 0.21 gi|224994171 roundabout 1 isoform c [Homo sapiens] 34 0.21 gi|19743806 roundabout 1 isoform b [Homo sapiens] 34 0.21 gi|239748173 PREDICTED: similar to roundabout 1 isoform 1 [Homo ... 34 0.21 gi|239748171 PREDICTED: similar to roundabout 1 isoform 2 [Homo ... 34 0.21 gi|4506569 roundabout 1 isoform a [Homo sapiens] 34 0.21 gi|169203160 PREDICTED: hypothetical protein [Homo sapiens] 31 1.4 gi|169203656 PREDICTED: hypothetical protein [Homo sapiens] 31 1.4 gi|169202387 PREDICTED: hypothetical protein [Homo sapiens] 31 1.4 gi|113204617 skeletal muscle ryanodine receptor isoform 2 [Homo ... 31 1.8 gi|113204615 skeletal muscle ryanodine receptor isoform 1 [Homo ... 31 1.8 gi|38788380 dehydrogenase E1 and transketolase domain containing... 30 2.3 gi|31742505 Rho family guanine-nucleotide exchange factor [Homo ... 29 5.2 gi|115387104 aldehyde dehydrogenase 9A1 [Homo sapiens] 29 6.8 gi|72534720 IQ motif containing H isoform 1 [Homo sapiens] 28 8.9 gi|12232475 IQ motif containing H isoform 2 [Homo sapiens] 28 8.9 gi|9845285 cytochrome P450, family 26, subfamily b, polypeptide ... 28 8.9 >gi|7661734 mRNA decapping enzyme [Homo sapiens] Length = 337 Score = 681 bits (1757), Expect = 0.0 Identities = 337/337 (100%), Positives = 337/337 (100%) Query: 1 MADAAPQLGKRKRELDVEEAHAASTEEKEAGVGNGTCAPVRLPFSGFRLQKVLRESARDK 60 MADAAPQLGKRKRELDVEEAHAASTEEKEAGVGNGTCAPVRLPFSGFRLQKVLRESARDK Sbjct: 1 MADAAPQLGKRKRELDVEEAHAASTEEKEAGVGNGTCAPVRLPFSGFRLQKVLRESARDK 60 Query: 61 IIFLHGKVNEASGDGDGEDAVVILEKTPFQVEQVAQLLTGSPELQLQFSNDIYSTYHLFP 120 IIFLHGKVNEASGDGDGEDAVVILEKTPFQVEQVAQLLTGSPELQLQFSNDIYSTYHLFP Sbjct: 61 IIFLHGKVNEASGDGDGEDAVVILEKTPFQVEQVAQLLTGSPELQLQFSNDIYSTYHLFP 120 Query: 121 PRQLNDVKTTVVYPATEKHLQKYLRQDLRLIRETGDDYRNITLPHLESQSLSIQWVYNIL 180 PRQLNDVKTTVVYPATEKHLQKYLRQDLRLIRETGDDYRNITLPHLESQSLSIQWVYNIL Sbjct: 121 PRQLNDVKTTVVYPATEKHLQKYLRQDLRLIRETGDDYRNITLPHLESQSLSIQWVYNIL 180 Query: 181 DKKAEADRIVFENPDPSDGFVLIPDLKWNQQQLDDLYLIAICHRRGIRSLRDLTPEHLPL 240 DKKAEADRIVFENPDPSDGFVLIPDLKWNQQQLDDLYLIAICHRRGIRSLRDLTPEHLPL Sbjct: 181 DKKAEADRIVFENPDPSDGFVLIPDLKWNQQQLDDLYLIAICHRRGIRSLRDLTPEHLPL 240 Query: 241 LRNILHQGQEAILQRYRMKGDHLRVYLHYLPSYYHLHVHFTALGFEAPGSGVERAHLLAE 300 LRNILHQGQEAILQRYRMKGDHLRVYLHYLPSYYHLHVHFTALGFEAPGSGVERAHLLAE Sbjct: 241 LRNILHQGQEAILQRYRMKGDHLRVYLHYLPSYYHLHVHFTALGFEAPGSGVERAHLLAE 300 Query: 301 VIENLECDPRHYQQRTLTFALRADDPLLKLLQEAQQS 337 VIENLECDPRHYQQRTLTFALRADDPLLKLLQEAQQS Sbjct: 301 VIENLECDPRHYQQRTLTFALRADDPLLKLLQEAQQS 337 >gi|28329436 aprataxin isoform a [Homo sapiens] Length = 342 Score = 38.1 bits (87), Expect = 0.011 Identities = 19/62 (30%), Positives = 34/62 (54%) Query: 227 IRSLRDLTPEHLPLLRNILHQGQEAILQRYRMKGDHLRVYLHYLPSYYHLHVHFTALGFE 286 I SL+ + EHL LL+++ G++ I+ R+ H +PS H+H+H + F+ Sbjct: 210 ISSLKAVAREHLELLKHMHTVGEKVIVDFAGSSKLRFRLGYHAIPSMSHVHLHVISQDFD 269 Query: 287 AP 288 +P Sbjct: 270 SP 271 >gi|28329433 aprataxin isoform c [Homo sapiens] Length = 254 Score = 38.1 bits (87), Expect = 0.011 Identities = 19/62 (30%), Positives = 34/62 (54%) Query: 227 IRSLRDLTPEHLPLLRNILHQGQEAILQRYRMKGDHLRVYLHYLPSYYHLHVHFTALGFE 286 I SL+ + EHL LL+++ G++ I+ R+ H +PS H+H+H + F+ Sbjct: 122 ISSLKAVAREHLELLKHMHTVGEKVIVDFAGSSKLRFRLGYHAIPSMSHVHLHVISQDFD 181 Query: 287 AP 288 +P Sbjct: 182 SP 183 >gi|28329427 aprataxin isoform d [Homo sapiens] Length = 168 Score = 38.1 bits (87), Expect = 0.011 Identities = 19/62 (30%), Positives = 34/62 (54%) Query: 227 IRSLRDLTPEHLPLLRNILHQGQEAILQRYRMKGDHLRVYLHYLPSYYHLHVHFTALGFE 286 I SL+ + EHL LL+++ G++ I+ R+ H +PS H+H+H + F+ Sbjct: 36 ISSLKAVAREHLELLKHMHTVGEKVIVDFAGSSKLRFRLGYHAIPSMSHVHLHVISQDFD 95 Query: 287 AP 288 +P Sbjct: 96 SP 97 >gi|28329430 aprataxin isoform b [Homo sapiens] Length = 306 Score = 38.1 bits (87), Expect = 0.011 Identities = 19/62 (30%), Positives = 34/62 (54%) Query: 227 IRSLRDLTPEHLPLLRNILHQGQEAILQRYRMKGDHLRVYLHYLPSYYHLHVHFTALGFE 286 I SL+ + EHL LL+++ G++ I+ R+ H +PS H+H+H + F+ Sbjct: 224 ISSLKAVAREHLELLKHMHTVGEKVIVDFAGSSKLRFRLGYHAIPSMSHVHLHVISQDFD 283 Query: 287 AP 288 +P Sbjct: 284 SP 285 >gi|8923156 aprataxin isoform d [Homo sapiens] Length = 168 Score = 38.1 bits (87), Expect = 0.011 Identities = 19/62 (30%), Positives = 34/62 (54%) Query: 227 IRSLRDLTPEHLPLLRNILHQGQEAILQRYRMKGDHLRVYLHYLPSYYHLHVHFTALGFE 286 I SL+ + EHL LL+++ G++ I+ R+ H +PS H+H+H + F+ Sbjct: 36 ISSLKAVAREHLELLKHMHTVGEKVIVDFAGSSKLRFRLGYHAIPSMSHVHLHVISQDFD 95 Query: 287 AP 288 +P Sbjct: 96 SP 97 >gi|24415404 MDN1, midasin homolog [Homo sapiens] Length = 5596 Score = 37.0 bits (84), Expect = 0.025 Identities = 33/149 (22%), Positives = 64/149 (42%), Gaps = 12/149 (8%) Query: 88 PFQVEQVAQLLTGSPELQLQFSNDIYSTYHLFPPRQLNDVKTTVVYPATEKHLQKYLRQD 147 PF ++ + +++ L+F+ +TY + P L ++ AT + ++ Sbjct: 2480 PFTLQDLEKIMQSPSPENLKFNAVEVNTYWIDEPDVLVMAVKLLIERATNQDWMLRVKWL 2539 Query: 148 LRLIRETGDDYRNITLPHLESQSLSIQWVYNILDKKAEADRIVFENPDPSDGFVLIPDLK 207 L + +I + HLE+ + S++ Y+ A ++ P+ +D FV+ D + Sbjct: 2540 YHLAKNIPQGLESIQI-HLEASAASLRNFYSHSLSGAVSNVFKILQPNTTDEFVIPLDPR 2598 Query: 208 WNQQQLDDLYLIAICHRRGIRSLRDLTPE 236 WN Q LD IR+L D P+ Sbjct: 2599 WNMQALD-----------MIRNLMDFDPQ 2616 >gi|224994173 roundabout 1 isoform d [Homo sapiens] Length = 1551 Score = 33.9 bits (76), Expect = 0.21 Identities = 32/111 (28%), Positives = 52/111 (46%), Gaps = 23/111 (20%) Query: 114 STYHLFPPRQLND-VKTTVVYPATEKHLQKYLRQDLRLIRETGDDYRNITLPH-LESQSL 171 + Y + P Q++D VKT V P ++ K ++ RE G+ ++ P L S S+ Sbjct: 602 NAYGISDPSQISDPVKTQDVLPTSQGVDHKQVQ------RELGNAVLHLHNPTVLSSSSI 655 Query: 172 SIQWV----------YNILDKKA-----EADRIVFENPDPSDGFVLIPDLK 207 + W Y IL + + E+D +VFE P+ V+IPDL+ Sbjct: 656 EVHWTVDQQSQYIQGYKILYRPSGANHGESDWLVFEVRTPAKNSVVIPDLR 706 >gi|224994171 roundabout 1 isoform c [Homo sapiens] Length = 1606 Score = 33.9 bits (76), Expect = 0.21 Identities = 32/111 (28%), Positives = 52/111 (46%), Gaps = 23/111 (20%) Query: 114 STYHLFPPRQLND-VKTTVVYPATEKHLQKYLRQDLRLIRETGDDYRNITLPH-LESQSL 171 + Y + P Q++D VKT V P ++ K ++ RE G+ ++ P L S S+ Sbjct: 602 NAYGISDPSQISDPVKTQDVLPTSQGVDHKQVQ------RELGNAVLHLHNPTVLSSSSI 655 Query: 172 SIQWV----------YNILDKKA-----EADRIVFENPDPSDGFVLIPDLK 207 + W Y IL + + E+D +VFE P+ V+IPDL+ Sbjct: 656 EVHWTVDQQSQYIQGYKILYRPSGANHGESDWLVFEVRTPAKNSVVIPDLR 706 >gi|19743806 roundabout 1 isoform b [Homo sapiens] Length = 1612 Score = 33.9 bits (76), Expect = 0.21 Identities = 32/111 (28%), Positives = 52/111 (46%), Gaps = 23/111 (20%) Query: 114 STYHLFPPRQLND-VKTTVVYPATEKHLQKYLRQDLRLIRETGDDYRNITLPH-LESQSL 171 + Y + P Q++D VKT V P ++ K ++ RE G+ ++ P L S S+ Sbjct: 599 NAYGISDPSQISDPVKTQDVLPTSQGVDHKQVQ------RELGNAVLHLHNPTVLSSSSI 652 Query: 172 SIQWV----------YNILDKKA-----EADRIVFENPDPSDGFVLIPDLK 207 + W Y IL + + E+D +VFE P+ V+IPDL+ Sbjct: 653 EVHWTVDQQSQYIQGYKILYRPSGANHGESDWLVFEVRTPAKNSVVIPDLR 703 >gi|239748173 PREDICTED: similar to roundabout 1 isoform 1 [Homo sapiens] Length = 1562 Score = 33.9 bits (76), Expect = 0.21 Identities = 32/111 (28%), Positives = 52/111 (46%), Gaps = 23/111 (20%) Query: 114 STYHLFPPRQLND-VKTTVVYPATEKHLQKYLRQDLRLIRETGDDYRNITLPH-LESQSL 171 + Y + P Q++D VKT V P ++ K ++ RE G+ ++ P L S S+ Sbjct: 602 NAYGISDPSQISDPVKTQDVLPTSQGVDHKQVQ------RELGNAVLHLHNPTVLSSSSI 655 Query: 172 SIQWV----------YNILDKKA-----EADRIVFENPDPSDGFVLIPDLK 207 + W Y IL + + E+D +VFE P+ V+IPDL+ Sbjct: 656 EVHWTVDQQSQYIQGYKILYRPSGANHGESDWLVFEVRTPAKNSVVIPDLR 706 >gi|239748171 PREDICTED: similar to roundabout 1 isoform 2 [Homo sapiens] Length = 1615 Score = 33.9 bits (76), Expect = 0.21 Identities = 32/111 (28%), Positives = 52/111 (46%), Gaps = 23/111 (20%) Query: 114 STYHLFPPRQLND-VKTTVVYPATEKHLQKYLRQDLRLIRETGDDYRNITLPH-LESQSL 171 + Y + P Q++D VKT V P ++ K ++ RE G+ ++ P L S S+ Sbjct: 602 NAYGISDPSQISDPVKTQDVLPTSQGVDHKQVQ------RELGNAVLHLHNPTVLSSSSI 655 Query: 172 SIQWV----------YNILDKKA-----EADRIVFENPDPSDGFVLIPDLK 207 + W Y IL + + E+D +VFE P+ V+IPDL+ Sbjct: 656 EVHWTVDQQSQYIQGYKILYRPSGANHGESDWLVFEVRTPAKNSVVIPDLR 706 >gi|4506569 roundabout 1 isoform a [Homo sapiens] Length = 1651 Score = 33.9 bits (76), Expect = 0.21 Identities = 32/111 (28%), Positives = 52/111 (46%), Gaps = 23/111 (20%) Query: 114 STYHLFPPRQLND-VKTTVVYPATEKHLQKYLRQDLRLIRETGDDYRNITLPH-LESQSL 171 + Y + P Q++D VKT V P ++ K ++ RE G+ ++ P L S S+ Sbjct: 638 NAYGISDPSQISDPVKTQDVLPTSQGVDHKQVQ------RELGNAVLHLHNPTVLSSSSI 691 Query: 172 SIQWV----------YNILDKKA-----EADRIVFENPDPSDGFVLIPDLK 207 + W Y IL + + E+D +VFE P+ V+IPDL+ Sbjct: 692 EVHWTVDQQSQYIQGYKILYRPSGANHGESDWLVFEVRTPAKNSVVIPDLR 742 >gi|169203160 PREDICTED: hypothetical protein [Homo sapiens] Length = 638 Score = 31.2 bits (69), Expect = 1.4 Identities = 15/35 (42%), Positives = 19/35 (54%) Query: 9 GKRKRELDVEEAHAASTEEKEAGVGNGTCAPVRLP 43 G+R REL EE S ++ VG G+ AP R P Sbjct: 441 GRRPRELGTEETTVQSAAKRRLSVGTGSRAPGRKP 475 >gi|169203656 PREDICTED: hypothetical protein [Homo sapiens] Length = 638 Score = 31.2 bits (69), Expect = 1.4 Identities = 15/35 (42%), Positives = 19/35 (54%) Query: 9 GKRKRELDVEEAHAASTEEKEAGVGNGTCAPVRLP 43 G+R REL EE S ++ VG G+ AP R P Sbjct: 441 GRRPRELGTEETTVQSAAKRRLSVGTGSRAPGRKP 475 >gi|169202387 PREDICTED: hypothetical protein [Homo sapiens] Length = 638 Score = 31.2 bits (69), Expect = 1.4 Identities = 15/35 (42%), Positives = 19/35 (54%) Query: 9 GKRKRELDVEEAHAASTEEKEAGVGNGTCAPVRLP 43 G+R REL EE S ++ VG G+ AP R P Sbjct: 441 GRRPRELGTEETTVQSAAKRRLSVGTGSRAPGRKP 475 >gi|113204617 skeletal muscle ryanodine receptor isoform 2 [Homo sapiens] Length = 5033 Score = 30.8 bits (68), Expect = 1.8 Identities = 28/94 (29%), Positives = 45/94 (47%), Gaps = 1/94 (1%) Query: 154 TGDDYRNITLPHLESQSLSIQWVYNILDKKAEADRIVFENPDPSDGFVLIPDLKWNQQQL 213 T D+ L LE+ S ++ +Y +L + E I+ EN S L+ N + L Sbjct: 541 TNLDWLVSKLDRLEASSGILEVLYCVLIESPEVLNIIQENHIKSI-ISLLDKHGRNHKVL 599 Query: 214 DDLYLIAICHRRGIRSLRDLTPEHLPLLRNILHQ 247 D L + +C+ +RS +DL E+L R +L Q Sbjct: 600 DVLCSLCVCNGVAVRSNQDLITENLLPGRELLLQ 633 >gi|113204615 skeletal muscle ryanodine receptor isoform 1 [Homo sapiens] Length = 5038 Score = 30.8 bits (68), Expect = 1.8 Identities = 28/94 (29%), Positives = 45/94 (47%), Gaps = 1/94 (1%) Query: 154 TGDDYRNITLPHLESQSLSIQWVYNILDKKAEADRIVFENPDPSDGFVLIPDLKWNQQQL 213 T D+ L LE+ S ++ +Y +L + E I+ EN S L+ N + L Sbjct: 541 TNLDWLVSKLDRLEASSGILEVLYCVLIESPEVLNIIQENHIKSI-ISLLDKHGRNHKVL 599 Query: 214 DDLYLIAICHRRGIRSLRDLTPEHLPLLRNILHQ 247 D L + +C+ +RS +DL E+L R +L Q Sbjct: 600 DVLCSLCVCNGVAVRSNQDLITENLLPGRELLLQ 633 >gi|38788380 dehydrogenase E1 and transketolase domain containing 1 [Homo sapiens] Length = 919 Score = 30.4 bits (67), Expect = 2.3 Identities = 30/110 (27%), Positives = 45/110 (40%), Gaps = 7/110 (6%) Query: 181 DKKAEADRIVFENPDPSDGFVLIPDL---KWNQQQLDD-LYLIAICHR--RGIRSLRDLT 234 ++ A R+ FE V+I L +W +LD+ Y I ++ R +S+ D Sbjct: 403 EEVVRATRLAFEYQRQFRKDVIIDLLCYRQWGHNELDEPFYTNPIMYKIIRARKSIPDTY 462 Query: 235 PEHLPLLRNILHQGQEAILQRYRMK-GDHLRVYLHYLPSYYHLHVHFTAL 283 EHL + + I Y K DHL HY P +L H+ L Sbjct: 463 AEHLIAGGLMTQEEVSEIKSSYYAKLNDHLNNMAHYRPPALNLQAHWQGL 512 >gi|31742505 Rho family guanine-nucleotide exchange factor [Homo sapiens] Length = 1114 Score = 29.3 bits (64), Expect = 5.2 Identities = 14/28 (50%), Positives = 15/28 (53%) Query: 12 KRELDVEEAHAASTEEKEAGVGNGTCAP 39 K E D EE STEE+ AG G AP Sbjct: 1066 KEERDEEETATRSTEEERAGASTGRLAP 1093 >gi|115387104 aldehyde dehydrogenase 9A1 [Homo sapiens] Length = 518 Score = 28.9 bits (63), Expect = 6.8 Identities = 21/68 (30%), Positives = 30/68 (44%), Gaps = 4/68 (5%) Query: 16 DVEEAHAASTEEKEAG---VGNGTCAPVRLPFSGFRLQKVLRESARDKIIFLHGKVNEAS 72 D++ AH E +AG + N +PV LPF G++ RE+ R I + Sbjct: 451 DIQRAHRV-VAELQAGTCFINNYNVSPVELPFGGYKKSGFGRENGRVTIEYYSQLKTVCV 509 Query: 73 GDGDGEDA 80 GD E A Sbjct: 510 EMGDVESA 517 >gi|72534720 IQ motif containing H isoform 1 [Homo sapiens] Length = 1027 Score = 28.5 bits (62), Expect = 8.9 Identities = 12/52 (23%), Positives = 26/52 (50%) Query: 237 HLPLLRNILHQGQEAILQRYRMKGDHLRVYLHYLPSYYHLHVHFTALGFEAP 288 H L+ IL + ++ L+ +R++ HL + + + +H +LG+ P Sbjct: 411 HKTRLKKILKESRQRHLENFRIRAKHLAANWNRIRTSRRTIIHIPSLGYSQP 462 >gi|12232475 IQ motif containing H isoform 2 [Homo sapiens] Length = 621 Score = 28.5 bits (62), Expect = 8.9 Identities = 12/52 (23%), Positives = 26/52 (50%) Query: 237 HLPLLRNILHQGQEAILQRYRMKGDHLRVYLHYLPSYYHLHVHFTALGFEAP 288 H L+ IL + ++ L+ +R++ HL + + + +H +LG+ P Sbjct: 163 HKTRLKKILKESRQRHLENFRIRAKHLAANWNRIRTSRRTIIHIPSLGYSQP 214 >gi|9845285 cytochrome P450, family 26, subfamily b, polypeptide 1 [Homo sapiens] Length = 512 Score = 28.5 bits (62), Expect = 8.9 Identities = 18/44 (40%), Positives = 23/44 (52%), Gaps = 8/44 (18%) Query: 32 VGNGTCAPVRLPFSGFR--------LQKVLRESARDKIIFLHGK 67 V N PV LPFSG+R LQK L ++ R+K+ GK Sbjct: 218 VDNVFSLPVDLPFSGYRRGIQARQILQKGLEKAIREKLQCTQGK 261 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.320 0.138 0.405 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 13,366,062 Number of Sequences: 37866 Number of extensions: 608421 Number of successful extensions: 1295 Number of sequences better than 10.0: 24 Number of HSP's better than 10.0 without gapping: 13 Number of HSP's successfully gapped in prelim test: 11 Number of HSP's that attempted gapping in prelim test: 1277 Number of HSP's gapped (non-prelim): 29 length of query: 337 length of database: 18,247,518 effective HSP length: 103 effective length of query: 234 effective length of database: 14,347,320 effective search space: 3357272880 effective search space used: 3357272880 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.