BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|7661566 integrator complex subunit 7 [Homo sapiens] (962 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|7661566 integrator complex subunit 7 [Homo sapiens] 1875 0.0 gi|21361794 TIP120 protein [Homo sapiens] 36 0.20 gi|27477070 BTAF1 RNA polymerase II, B-TFIID transcription facto... 36 0.20 gi|24308211 integrator complex subunit 2 [Homo sapiens] 34 0.58 gi|39930351 dynamin binding protein [Homo sapiens] 34 0.58 gi|23097308 spectrin repeat containing, nuclear envelope 1 isofo... 33 0.98 gi|154277116 spectrin repeat containing, nuclear envelope 1 isof... 33 0.98 gi|241982712 TBP-interacting protein isoform 1 [Homo sapiens] 33 1.3 gi|209969838 transportin 2 (importin 3, karyopherin beta 2b) iso... 33 1.3 gi|209969836 transportin 2 (importin 3, karyopherin beta 2b) iso... 33 1.3 gi|48675813 transportin 2 (importin 3, karyopherin beta 2b) isof... 33 1.3 gi|110347429 mediator complex subunit 12 [Homo sapiens] 32 2.9 gi|21536485 HIR histone cell cycle regulation defective homolog ... 32 2.9 gi|94536868 PR domain containing 15 isoform 2 [Homo sapiens] 32 2.9 gi|93204879 PR domain containing 15 isoform 1 [Homo sapiens] 32 2.9 gi|7657269 PDS5, regulator of cohesion maintenance, homolog B [H... 32 3.7 gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 32 3.7 gi|11968009 SIL1 protein precursor [Homo sapiens] 31 4.9 gi|83641896 SIL1 protein precursor [Homo sapiens] 31 4.9 gi|118498345 AT-binding transcription factor 1 [Homo sapiens] 31 4.9 gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens] 31 4.9 gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] 31 4.9 gi|55956904 mitogen-activated protein kinase kinase kinase 4 iso... 31 4.9 gi|55956902 mitogen-activated protein kinase kinase kinase 4 iso... 31 4.9 gi|5730059 fibroblast growth factor receptor substrate 3 [Homo s... 31 6.4 gi|38787935 BMP-2 inducible kinase isoform a [Homo sapiens] 30 8.3 gi|38787904 BMP-2 inducible kinase isoform b [Homo sapiens] 30 8.3 gi|239745655 PREDICTED: family with sequence similarity 157, mem... 30 8.3 gi|55956910 meningioma 1 [Homo sapiens] 30 8.3 gi|41872374 polo-like kinase 3 [Homo sapiens] 30 8.3 >gi|7661566 integrator complex subunit 7 [Homo sapiens] Length = 962 Score = 1875 bits (4858), Expect = 0.0 Identities = 962/962 (100%), Positives = 962/962 (100%) Query: 1 MASNSTKSFLADAGYGEQELDANSALMELDKGLRSGKLGEQCEAVVRFPRLFQKYPFPIL 60 MASNSTKSFLADAGYGEQELDANSALMELDKGLRSGKLGEQCEAVVRFPRLFQKYPFPIL Sbjct: 1 MASNSTKSFLADAGYGEQELDANSALMELDKGLRSGKLGEQCEAVVRFPRLFQKYPFPIL 60 Query: 61 INSAFLKLADVFRVGNNFLRLCVLKVTQQSEKHLEKILNVDEFVKRIFSVIHSNDPVARA 120 INSAFLKLADVFRVGNNFLRLCVLKVTQQSEKHLEKILNVDEFVKRIFSVIHSNDPVARA Sbjct: 61 INSAFLKLADVFRVGNNFLRLCVLKVTQQSEKHLEKILNVDEFVKRIFSVIHSNDPVARA 120 Query: 121 ITLRMLGSLASIIPERKNAHHSIRQSLDSHDNVEVEAAVFAAANFSAQSKDFAVGICNKI 180 ITLRMLGSLASIIPERKNAHHSIRQSLDSHDNVEVEAAVFAAANFSAQSKDFAVGICNKI Sbjct: 121 ITLRMLGSLASIIPERKNAHHSIRQSLDSHDNVEVEAAVFAAANFSAQSKDFAVGICNKI 180 Query: 181 SEMIQGLATPVDLKLKLIPILQHMHHDAILASSARQLLQQLVTSYPSTKMVIVSLHTFTL 240 SEMIQGLATPVDLKLKLIPILQHMHHDAILASSARQLLQQLVTSYPSTKMVIVSLHTFTL Sbjct: 181 SEMIQGLATPVDLKLKLIPILQHMHHDAILASSARQLLQQLVTSYPSTKMVIVSLHTFTL 240 Query: 241 LAASSLVDTPKQIQLLLQYLKNDPRKAVKRLAIQDLKLLANKTPHTWSRENIQALCECAL 300 LAASSLVDTPKQIQLLLQYLKNDPRKAVKRLAIQDLKLLANKTPHTWSRENIQALCECAL Sbjct: 241 LAASSLVDTPKQIQLLLQYLKNDPRKAVKRLAIQDLKLLANKTPHTWSRENIQALCECAL 300 Query: 301 QTPYDSLKLGMLSVLSTLSGTIAIKHYFSIVPGNVSSSPRSSDLVKLAQECCYHNNRGIA 360 QTPYDSLKLGMLSVLSTLSGTIAIKHYFSIVPGNVSSSPRSSDLVKLAQECCYHNNRGIA Sbjct: 301 QTPYDSLKLGMLSVLSTLSGTIAIKHYFSIVPGNVSSSPRSSDLVKLAQECCYHNNRGIA 360 Query: 361 AHGVRVLTNITVSCQEKDLLALEQDAVFGLESLLVLCSQDDSPGAQATLKIALNCMVKLA 420 AHGVRVLTNITVSCQEKDLLALEQDAVFGLESLLVLCSQDDSPGAQATLKIALNCMVKLA Sbjct: 361 AHGVRVLTNITVSCQEKDLLALEQDAVFGLESLLVLCSQDDSPGAQATLKIALNCMVKLA 420 Query: 421 KGRPHLSQSVVETLLTQLHSAQDAARILMCHCLAAIAMQLPVLGDGMLGDLMELYKVIGR 480 KGRPHLSQSVVETLLTQLHSAQDAARILMCHCLAAIAMQLPVLGDGMLGDLMELYKVIGR Sbjct: 421 KGRPHLSQSVVETLLTQLHSAQDAARILMCHCLAAIAMQLPVLGDGMLGDLMELYKVIGR 480 Query: 481 SATDKQQELLVSLATVIFVASQKALSVESKAVIKQQLESVSNGWTVYRIARQASRMGNHD 540 SATDKQQELLVSLATVIFVASQKALSVESKAVIKQQLESVSNGWTVYRIARQASRMGNHD Sbjct: 481 SATDKQQELLVSLATVIFVASQKALSVESKAVIKQQLESVSNGWTVYRIARQASRMGNHD 540 Query: 541 MAKELYQSLLTQVASEHFYFWLNSLKEFSHAEQCLTGLQEENYSSALSCIAESLKFYHKG 600 MAKELYQSLLTQVASEHFYFWLNSLKEFSHAEQCLTGLQEENYSSALSCIAESLKFYHKG Sbjct: 541 MAKELYQSLLTQVASEHFYFWLNSLKEFSHAEQCLTGLQEENYSSALSCIAESLKFYHKG 600 Query: 601 IASLTAASTPLNPLSFQCEFVKLRIDLLQAFSQLICTCNSLKTSPPPAIATTIAMTLGND 660 IASLTAASTPLNPLSFQCEFVKLRIDLLQAFSQLICTCNSLKTSPPPAIATTIAMTLGND Sbjct: 601 IASLTAASTPLNPLSFQCEFVKLRIDLLQAFSQLICTCNSLKTSPPPAIATTIAMTLGND 660 Query: 661 LQRCGRISNQMKQSMEEFRSLASRYGDLYQASFDADSATLRNVELQQQSCLLISHAIEAL 720 LQRCGRISNQMKQSMEEFRSLASRYGDLYQASFDADSATLRNVELQQQSCLLISHAIEAL Sbjct: 661 LQRCGRISNQMKQSMEEFRSLASRYGDLYQASFDADSATLRNVELQQQSCLLISHAIEAL 720 Query: 721 ILDPESASFQEYGSTGTAHADSEYERRMMSVYNHVLEEVESLNRKYTPVSYMHTACLCNA 780 ILDPESASFQEYGSTGTAHADSEYERRMMSVYNHVLEEVESLNRKYTPVSYMHTACLCNA Sbjct: 721 ILDPESASFQEYGSTGTAHADSEYERRMMSVYNHVLEEVESLNRKYTPVSYMHTACLCNA 780 Query: 781 IIALLKVPLSFQRYFFQKLQSTSIKLALSPSPRNPAEPIAVQNNQQLALKVEGVVQHGSK 840 IIALLKVPLSFQRYFFQKLQSTSIKLALSPSPRNPAEPIAVQNNQQLALKVEGVVQHGSK Sbjct: 781 IIALLKVPLSFQRYFFQKLQSTSIKLALSPSPRNPAEPIAVQNNQQLALKVEGVVQHGSK 840 Query: 841 PGLFRKIQSVCLNVSSTLQSKSGQDYKIPIDNMTNEMEQRVEPHNDYFSTQFLLNFAILG 900 PGLFRKIQSVCLNVSSTLQSKSGQDYKIPIDNMTNEMEQRVEPHNDYFSTQFLLNFAILG Sbjct: 841 PGLFRKIQSVCLNVSSTLQSKSGQDYKIPIDNMTNEMEQRVEPHNDYFSTQFLLNFAILG 900 Query: 901 THNITVESSVKDANGIVWKTGPRTTIFVKSLEDPYSQQIRLQQQQAQQPLQQQQQRNAYT 960 THNITVESSVKDANGIVWKTGPRTTIFVKSLEDPYSQQIRLQQQQAQQPLQQQQQRNAYT Sbjct: 901 THNITVESSVKDANGIVWKTGPRTTIFVKSLEDPYSQQIRLQQQQAQQPLQQQQQRNAYT 960 Query: 961 RF 962 RF Sbjct: 961 RF 962 >gi|21361794 TIP120 protein [Homo sapiens] Length = 1230 Score = 35.8 bits (81), Expect = 0.20 Identities = 32/136 (23%), Positives = 66/136 (48%), Gaps = 6/136 (4%) Query: 368 TNITVSCQEKDLLALEQDAVFGLESLLVLCSQDDSPGAQATLKIALNCMVKL-AKGRPHL 426 TN ++ +KD + L+ D+ + +++ +D + Q +A+ C+ L +K + + Sbjct: 27 TNDLMTELQKDSIKLDDDSERKVVKMILKLLEDKNGEVQ---NLAVKCLGPLVSKVKEYQ 83 Query: 427 SQSVVETLLTQLHSAQDAARILMCHCLAAIAMQLPVLGDGMLGDLMELYKVIGR--SATD 484 +++V+TL T + S ++ R + L + +LP G K+ GR SA Sbjct: 84 VETIVDTLCTNMLSDKEQLRDISSIGLKTVIGELPPASSGSALAANVCKKITGRLTSAIA 143 Query: 485 KQQELLVSLATVIFVA 500 KQ+++ V L + +A Sbjct: 144 KQEDVSVQLEALDIMA 159 >gi|27477070 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa [Homo sapiens] Length = 1849 Score = 35.8 bits (81), Expect = 0.20 Identities = 86/408 (21%), Positives = 158/408 (38%), Gaps = 90/408 (22%) Query: 213 SARQLLQQLVTSYPSTKMVI-VSLHTFTLLAASSLVDTPKQ----IQLLLQYLKNDPRKA 267 S RQ +Q VT V+ + +HTF A SL P++ I+ L++ +K + Sbjct: 833 SKRQQVQMTVTETNQEWQVLQLRVHTFAACAVVSLQQLPEKLNPIIKPLMETIKKEENTL 892 Query: 268 VKRLAIQDLKLLANKTPHTWSRENIQALCECALQTPYDSLKLGMLSVLSTLSGTIAIKHY 327 V+ A Q + L L +C +TP + K ++ L ++ + Y Sbjct: 893 VQNYAAQCIAKL---------------LQQCTTRTPCPNSK-----IIKNLCSSLCVDPY 932 Query: 328 FS---IVPGNVSSSPRSSDLVKLAQECCYHN---NRGIAAHGVRVLTNITVSCQEKDLLA 381 + P S +S ++ +H +RGI IT+ +K A Sbjct: 933 LTPCVTCPVPTQSGQENSKGSTSEKDGMHHTVTKHRGI----------ITLYRHQKAAFA 982 Query: 382 LEQDAVFGLESLLVLCSQDDSPGAQATLKIALNCMVKLAKGRPHLSQSVVETLLTQLHSA 441 + G V D P + N +V+L + + + L Q A Sbjct: 983 ITSRR--GPTPKAVKAQIADLPAGSSG-----NILVELDEAQ--------KPYLVQRRGA 1027 Query: 442 QDAARILMCHCLAAIAMQLPVLGDGMLGDL---MELYKVIGRSATDK----QQELLVSLA 494 + A ++ H +A++LP L D M+G L +++ G+S DK QEL+ SL Sbjct: 1028 EFALTTIVKHFGGEMAVKLPHLWDAMVGPLRNTIDINNFDGKSLLDKGDSPAQELVNSLQ 1087 Query: 495 TVIFVASQKALSVESKAVIKQQLESVSNGWTVYRIARQASRMGNHDMAKELYQSLLTQVA 554 +F + ++ E ++ Q L +Y + S H A+ + +++++A Sbjct: 1088 --VFETAAASMDSELHPLLVQHLPH------LYMCLQYPSTAVRHMAARCV--GVMSKIA 1137 Query: 555 S--------EHFYFWLNSLKEFSHAEQCLTGLQEENYSSALSCIAESL 594 + E WL ++ + +++E AL+C+ E L Sbjct: 1138 TMETMNIFLEKVLPWLGAIDD---------SVKQEGAIEALACVMEQL 1176 >gi|24308211 integrator complex subunit 2 [Homo sapiens] Length = 1204 Score = 34.3 bits (77), Expect = 0.58 Identities = 22/49 (44%), Positives = 31/49 (63%), Gaps = 2/49 (4%) Query: 214 ARQLLQQLVTSYPSTKMVI--VSLHTFTLLAASSLVDTPKQIQLLLQYL 260 A QLLQ + + P+T + VSL LLA S+LV TP+Q QL++ +L Sbjct: 408 AEQLLQLMTSRPPATPAGVRFVSLSFCMLLAFSTLVSTPEQEQLMVVWL 456 >gi|39930351 dynamin binding protein [Homo sapiens] Length = 1577 Score = 34.3 bits (77), Expect = 0.58 Identities = 33/125 (26%), Positives = 54/125 (43%), Gaps = 12/125 (9%) Query: 642 KTSPPPAIATTIAMTLGNDLQRCGRISNQMKQSMEEFRSLASRYGDLYQASFDADSATLR 701 +TSP P + I + DL R ++ +EE + +SR L F + Sbjct: 687 QTSPCPLVLVRIE-EMERDLDMYSRAQEELNLMLEEKQDESSRAETLEDLKFCESNIESL 745 Query: 702 NVELQQQSCLLISHAIEALILDPESASFQEYGSTGTAHADSEYERRMMSVYNHVLEEVES 761 N+ELQQ E +L +S+S +G+ A++ E+RM+ V+EE+ Sbjct: 746 NMELQQLR--------EMTLLSSQSSSL--VAPSGSVSAENP-EQRMLEKRAKVIEELLQ 794 Query: 762 LNRKY 766 R Y Sbjct: 795 TERDY 799 >gi|23097308 spectrin repeat containing, nuclear envelope 1 isoform 2 [Homo sapiens] Length = 8749 Score = 33.5 bits (75), Expect = 0.98 Identities = 26/138 (18%), Positives = 59/138 (42%), Gaps = 10/138 (7%) Query: 178 NKISEMIQGLATPVDLKLKLIPILQHMHHDAILASSARQLLQQLVTSYPSTKMVIVSLHT 237 N + E+ + L TP DL+ ++Q + H + A+ L+ + I + T Sbjct: 2266 NDLKELTKNLETPPDLQFIEADLMQKLEHAKEITEVAKGTLKDFTAQSTQVEKFINDITT 2325 Query: 238 FTLLAASSLVDTPKQIQLLLQYLKNDPRKAVKRLAIQDLKLLANKTPHTWSRENIQALCE 297 + SL++ +N+ +A+K++ +L + ++ + ++EN+ +LC Sbjct: 2326 WFTKVEESLMNC----------AQNETCEALKKVKDIQKELQSQQSNISSTQENLNSLCR 2375 Query: 298 CALQTPYDSLKLGMLSVL 315 +SL M ++ Sbjct: 2376 KYHSAELESLGRAMTGLI 2393 >gi|154277116 spectrin repeat containing, nuclear envelope 1 isoform 1 [Homo sapiens] Length = 8797 Score = 33.5 bits (75), Expect = 0.98 Identities = 26/138 (18%), Positives = 59/138 (42%), Gaps = 10/138 (7%) Query: 178 NKISEMIQGLATPVDLKLKLIPILQHMHHDAILASSARQLLQQLVTSYPSTKMVIVSLHT 237 N + E+ + L TP DL+ ++Q + H + A+ L+ + I + T Sbjct: 2259 NDLKELTKNLETPPDLQFIEADLMQKLEHAKEITEVAKGTLKDFTAQSTQVEKFINDITT 2318 Query: 238 FTLLAASSLVDTPKQIQLLLQYLKNDPRKAVKRLAIQDLKLLANKTPHTWSRENIQALCE 297 + SL++ +N+ +A+K++ +L + ++ + ++EN+ +LC Sbjct: 2319 WFTKVEESLMNC----------AQNETCEALKKVKDIQKELQSQQSNISSTQENLNSLCR 2368 Query: 298 CALQTPYDSLKLGMLSVL 315 +SL M ++ Sbjct: 2369 KYHSAELESLGRAMTGLI 2386 >gi|241982712 TBP-interacting protein isoform 1 [Homo sapiens] Length = 1236 Score = 33.1 bits (74), Expect = 1.3 Identities = 31/131 (23%), Positives = 67/131 (51%), Gaps = 10/131 (7%) Query: 368 TNITVSCQEKDLLALEQDAVFGLESLLVLCSQDDSPGAQATLKIALNCMVKLA-KGRPHL 426 T+ +S +KD + L++D+ + +L+ +D + Q +A+ C+ L K + + Sbjct: 27 TSDLMSELQKDSIQLDEDSERKVVKMLLRLLEDKNGEVQ---NLAVKCLGPLVVKVKEYQ 83 Query: 427 SQSVVETLLTQLHSAQDAARILMCHCLAAIAMQLP--VLGDGMLGDLMELYKVIGR--SA 482 +++V+TL T + S ++ R + L + +LP G G+ ++ K+ G+ SA Sbjct: 84 VETIVDTLCTNMRSDKEQLRDIAGIGLKTVLSELPPAATGSGLATNVCR--KITGQLTSA 141 Query: 483 TDKQQELLVSL 493 +Q+++ V L Sbjct: 142 IAQQEDVAVQL 152 >gi|209969838 transportin 2 (importin 3, karyopherin beta 2b) isoform 1 [Homo sapiens] Length = 897 Score = 33.1 bits (74), Expect = 1.3 Identities = 22/68 (32%), Positives = 34/68 (50%), Gaps = 6/68 (8%) Query: 99 NVDEFVKRIFSVIHSNDPVARAITLRMLGSLASIIPERKNAH-HSIRQSL-----DSHDN 152 N+D F++ +F++ +DP R R L L + +R H HSI Q + D +N Sbjct: 210 NIDTFIEHLFALAVDDDPEVRKNVCRALVMLLEVRIDRLIPHMHSIIQYMLQRTQDHDEN 269 Query: 153 VEVEAAVF 160 V +EA F Sbjct: 270 VALEACEF 277 >gi|209969836 transportin 2 (importin 3, karyopherin beta 2b) isoform 3 [Homo sapiens] Length = 887 Score = 33.1 bits (74), Expect = 1.3 Identities = 22/68 (32%), Positives = 34/68 (50%), Gaps = 6/68 (8%) Query: 99 NVDEFVKRIFSVIHSNDPVARAITLRMLGSLASIIPERKNAH-HSIRQSL-----DSHDN 152 N+D F++ +F++ +DP R R L L + +R H HSI Q + D +N Sbjct: 210 NIDTFIEHLFALAVDDDPEVRKNVCRALVMLLEVRIDRLIPHMHSIIQYMLQRTQDHDEN 269 Query: 153 VEVEAAVF 160 V +EA F Sbjct: 270 VALEACEF 277 >gi|48675813 transportin 2 (importin 3, karyopherin beta 2b) isoform 2 [Homo sapiens] Length = 887 Score = 33.1 bits (74), Expect = 1.3 Identities = 22/68 (32%), Positives = 34/68 (50%), Gaps = 6/68 (8%) Query: 99 NVDEFVKRIFSVIHSNDPVARAITLRMLGSLASIIPERKNAH-HSIRQSL-----DSHDN 152 N+D F++ +F++ +DP R R L L + +R H HSI Q + D +N Sbjct: 210 NIDTFIEHLFALAVDDDPEVRKNVCRALVMLLEVRIDRLIPHMHSIIQYMLQRTQDHDEN 269 Query: 153 VEVEAAVF 160 V +EA F Sbjct: 270 VALEACEF 277 >gi|110347429 mediator complex subunit 12 [Homo sapiens] Length = 2177 Score = 32.0 bits (71), Expect = 2.9 Identities = 16/38 (42%), Positives = 22/38 (57%) Query: 919 KTGPRTTIFVKSLEDPYSQQIRLQQQQAQQPLQQQQQR 956 + G R+T + + QQ + QQQQ QQ QQQQQ+ Sbjct: 2039 QAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQ 2076 >gi|21536485 HIR histone cell cycle regulation defective homolog A [Homo sapiens] Length = 1017 Score = 32.0 bits (71), Expect = 2.9 Identities = 34/117 (29%), Positives = 55/117 (47%), Gaps = 14/117 (11%) Query: 357 RGIAAHGVRVLTNITVSCQEKDLLALEQDAVFGLESLLVLCSQDDS----PGAQAT---- 408 R A G LT++T + E+ EQ+ V L +L S DS P A+A+ Sbjct: 572 RSKATPGAPALTSMTPTAVER---LKEQNLVKELRPRDLLESSSDSDEKVPLAKASSLSK 628 Query: 409 --LKIALNCMVKLAKGRPHLSQSVVETLLT-QLHSAQDAARILMCHCLAAIAMQLPV 462 L++ + + K KGRP ++ L+ Q +A A + MC A+A++LP+ Sbjct: 629 RKLELEVETVEKKKKGRPRKDSRLMPVSLSVQSPAALTAEKEAMCLSAPALALKLPI 685 >gi|94536868 PR domain containing 15 isoform 2 [Homo sapiens] Length = 1178 Score = 32.0 bits (71), Expect = 2.9 Identities = 23/91 (25%), Positives = 40/91 (43%), Gaps = 4/91 (4%) Query: 870 IDNMTNEMEQRVEPH-NDYFSTQFLLNFAILGTHNITVESSVKDANGIVWKTGPRTTIFV 928 + N N+++ +P ++ S +N L + S + D + + W+ P+T + Sbjct: 1091 LHNRQNDVQIHPQPEASNPQSVAHFINLTTLVNSITPLGSQLSDQHPLTWRAVPQTDVLP 1150 Query: 929 KSLEDPYSQQIRLQQQQAQQPLQQQQQRNAY 959 S QQ Q QA+ QQQQQ +Y Sbjct: 1151 PSQPQAPPQQAAQPQVQAE---QQQQQMYSY 1178 >gi|93204879 PR domain containing 15 isoform 1 [Homo sapiens] Length = 1507 Score = 32.0 bits (71), Expect = 2.9 Identities = 23/91 (25%), Positives = 40/91 (43%), Gaps = 4/91 (4%) Query: 870 IDNMTNEMEQRVEPH-NDYFSTQFLLNFAILGTHNITVESSVKDANGIVWKTGPRTTIFV 928 + N N+++ +P ++ S +N L + S + D + + W+ P+T + Sbjct: 1420 LHNRQNDVQIHPQPEASNPQSVAHFINLTTLVNSITPLGSQLSDQHPLTWRAVPQTDVLP 1479 Query: 929 KSLEDPYSQQIRLQQQQAQQPLQQQQQRNAY 959 S QQ Q QA+ QQQQQ +Y Sbjct: 1480 PSQPQAPPQQAAQPQVQAE---QQQQQMYSY 1507 >gi|7657269 PDS5, regulator of cohesion maintenance, homolog B [Homo sapiens] Length = 1447 Score = 31.6 bits (70), Expect = 3.7 Identities = 19/66 (28%), Positives = 29/66 (43%) Query: 391 ESLLVLCSQDDSPGAQATLKIALNCMVKLAKGRPHLSQSVVETLLTQLHSAQDAARILMC 450 ESLL DD A+A L+I N K+ + PH+ +++ L + Sbjct: 671 ESLLACLKMDDEKVAEAALQIFKNTGSKIEEDFPHIRSALLPVLHHKSKKGPPRQAKYAI 730 Query: 451 HCLAAI 456 HC+ AI Sbjct: 731 HCIHAI 736 >gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo sapiens] Length = 5537 Score = 31.6 bits (70), Expect = 3.7 Identities = 15/20 (75%), Positives = 17/20 (85%) Query: 937 QQIRLQQQQAQQPLQQQQQR 956 QQ +LQQQQ QQ LQQQQQ+ Sbjct: 3927 QQQQLQQQQQQQQLQQQQQQ 3946 Score = 30.8 bits (68), Expect = 6.4 Identities = 14/28 (50%), Positives = 19/28 (67%) Query: 929 KSLEDPYSQQIRLQQQQAQQPLQQQQQR 956 + L+ QQ++ QQQQ QQ QQQQQ+ Sbjct: 3938 QQLQQQQQQQLQQQQQQLQQQQQQQQQQ 3965 Score = 30.4 bits (67), Expect = 8.3 Identities = 14/28 (50%), Positives = 19/28 (67%) Query: 929 KSLEDPYSQQIRLQQQQAQQPLQQQQQR 956 + L+ QQ++ QQQ QQ LQQQQQ+ Sbjct: 3910 QQLQQQQQQQLQQQQQLQQQQLQQQQQQ 3937 >gi|11968009 SIL1 protein precursor [Homo sapiens] Length = 461 Score = 31.2 bits (69), Expect = 4.9 Identities = 34/105 (32%), Positives = 50/105 (47%), Gaps = 17/105 (16%) Query: 218 LQQLVTSYPSTKMVIVSLHTFTLLAASSLVDTPKQIQLLLQYLKNDPRKAVKRLAIQDLK 277 LQ ++ ST+ ++ F L AA S PK +Q+ +A++ A+Q L Sbjct: 228 LQVVINGLNSTEPLVKEYAAFVLGAAFS--SNPK-VQV----------EAIEGGALQKLL 274 Query: 278 -LLANKTPHTWSRENIQALCECALQTPY---DSLKLGMLSVLSTL 318 +LA + P T ++ + ALC PY LKLG L VL TL Sbjct: 275 VILATEQPLTAKKKVLFALCSLLRHFPYAQRQFLKLGGLQVLRTL 319 >gi|83641896 SIL1 protein precursor [Homo sapiens] Length = 461 Score = 31.2 bits (69), Expect = 4.9 Identities = 34/105 (32%), Positives = 50/105 (47%), Gaps = 17/105 (16%) Query: 218 LQQLVTSYPSTKMVIVSLHTFTLLAASSLVDTPKQIQLLLQYLKNDPRKAVKRLAIQDLK 277 LQ ++ ST+ ++ F L AA S PK +Q+ +A++ A+Q L Sbjct: 228 LQVVINGLNSTEPLVKEYAAFVLGAAFS--SNPK-VQV----------EAIEGGALQKLL 274 Query: 278 -LLANKTPHTWSRENIQALCECALQTPY---DSLKLGMLSVLSTL 318 +LA + P T ++ + ALC PY LKLG L VL TL Sbjct: 275 VILATEQPLTAKKKVLFALCSLLRHFPYAQRQFLKLGGLQVLRTL 319 >gi|118498345 AT-binding transcription factor 1 [Homo sapiens] Length = 3703 Score = 31.2 bits (69), Expect = 4.9 Identities = 16/32 (50%), Positives = 20/32 (62%) Query: 929 KSLEDPYSQQIRLQQQQAQQPLQQQQQRNAYT 960 K L D + + + QQQQ QQ QQQQQ+ A T Sbjct: 1713 KKLADMIASRQQQQQQQQQQQQQQQQQQQAQT 1744 >gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens] Length = 788 Score = 31.2 bits (69), Expect = 4.9 Identities = 14/19 (73%), Positives = 15/19 (78%) Query: 937 QQIRLQQQQAQQPLQQQQQ 955 QQ+ LQQQQ QQ QQQQQ Sbjct: 156 QQVALQQQQQQQQFQQQQQ 174 Score = 30.8 bits (68), Expect = 6.4 Identities = 14/21 (66%), Positives = 17/21 (80%) Query: 938 QIRLQQQQAQQPLQQQQQRNA 958 Q++LQQQQ QQ QQQQQ+ A Sbjct: 243 QLQLQQQQQQQQQQQQQQQQA 263 >gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] Length = 748 Score = 31.2 bits (69), Expect = 4.9 Identities = 14/19 (73%), Positives = 15/19 (78%) Query: 937 QQIRLQQQQAQQPLQQQQQ 955 QQ+ LQQQQ QQ QQQQQ Sbjct: 156 QQVALQQQQQQQQFQQQQQ 174 Score = 30.8 bits (68), Expect = 6.4 Identities = 14/21 (66%), Positives = 17/21 (80%) Query: 938 QIRLQQQQAQQPLQQQQQRNA 958 Q++LQQQQ QQ QQQQQ+ A Sbjct: 243 QLQLQQQQQQQQQQQQQQQQA 263 >gi|55956904 mitogen-activated protein kinase kinase kinase 4 isoform a [Homo sapiens] Length = 1608 Score = 31.2 bits (69), Expect = 4.9 Identities = 22/79 (27%), Positives = 34/79 (43%), Gaps = 12/79 (15%) Query: 629 QAFSQLICTCNSLKTSPPPAIATTIAMTLGNDLQRCGRISNQMKQSMEEFRSLASRYGDL 688 Q+ L+ C +TS P IA + + L+ C RISN + R + Sbjct: 964 QSIEGLMTLCQE-QTSSQPVIAKALQQLKNDALELCNRISNAI-----------DRVDHM 1011 Query: 689 YQASFDADSATLRNVELQQ 707 + + FDA+ +V LQQ Sbjct: 1012 FTSEFDAEVDESESVTLQQ 1030 >gi|55956902 mitogen-activated protein kinase kinase kinase 4 isoform b [Homo sapiens] Length = 1558 Score = 31.2 bits (69), Expect = 4.9 Identities = 22/79 (27%), Positives = 34/79 (43%), Gaps = 12/79 (15%) Query: 629 QAFSQLICTCNSLKTSPPPAIATTIAMTLGNDLQRCGRISNQMKQSMEEFRSLASRYGDL 688 Q+ L+ C +TS P IA + + L+ C RISN + R + Sbjct: 964 QSIEGLMTLCQE-QTSSQPVIAKALQQLKNDALELCNRISNAI-----------DRVDHM 1011 Query: 689 YQASFDADSATLRNVELQQ 707 + + FDA+ +V LQQ Sbjct: 1012 FTSEFDAEVDESESVTLQQ 1030 >gi|5730059 fibroblast growth factor receptor substrate 3 [Homo sapiens] Length = 492 Score = 30.8 bits (68), Expect = 6.4 Identities = 26/105 (24%), Positives = 46/105 (43%), Gaps = 8/105 (7%) Query: 615 SFQCEFVKLRIDLLQAFSQLICTCNSLKTSPPPAIATTIAMTLGNDLQRCGRISNQMKQS 674 +F+C + +LLQ Q CNS+ P I T + DL R + N + + Sbjct: 88 AFKCSRAEEIFNLLQDLMQ----CNSINVMEEPVIITRNSHPAELDLPRAPQPPNALGYT 143 Query: 675 MEEFRSLASRYGDLYQASFDADSATLRNVELQQQSCLLISHAIEA 719 + F + G + A +++LR+ L ++S +HA+ A Sbjct: 144 VSSFSNGCPGEGPRFSAPRRLSTSSLRHPSLGEES----THALIA 184 >gi|38787935 BMP-2 inducible kinase isoform a [Homo sapiens] Length = 1161 Score = 30.4 bits (67), Expect = 8.3 Identities = 14/23 (60%), Positives = 17/23 (73%) Query: 934 PYSQQIRLQQQQAQQPLQQQQQR 956 P+ QQ + QQQQ QQ QQQQQ+ Sbjct: 458 PHQQQQQQQQQQQQQQQQQQQQQ 480 >gi|38787904 BMP-2 inducible kinase isoform b [Homo sapiens] Length = 662 Score = 30.4 bits (67), Expect = 8.3 Identities = 14/23 (60%), Positives = 17/23 (73%) Query: 934 PYSQQIRLQQQQAQQPLQQQQQR 956 P+ QQ + QQQQ QQ QQQQQ+ Sbjct: 458 PHQQQQQQQQQQQQQQQQQQQQQ 480 >gi|239745655 PREDICTED: family with sequence similarity 157, member C [Homo sapiens] Length = 387 Score = 30.4 bits (67), Expect = 8.3 Identities = 16/28 (57%), Positives = 17/28 (60%) Query: 929 KSLEDPYSQQIRLQQQQAQQPLQQQQQR 956 K ED Y R QQQQ QQ QQQQQ+ Sbjct: 61 KPSEDIYKNWRRQQQQQQQQQQQQQQQQ 88 >gi|55956910 meningioma 1 [Homo sapiens] Length = 1320 Score = 30.4 bits (67), Expect = 8.3 Identities = 15/28 (53%), Positives = 19/28 (67%) Query: 929 KSLEDPYSQQIRLQQQQAQQPLQQQQQR 956 +SL+ QQ + QQQQ QQ QQQQQ+ Sbjct: 520 QSLQQQQQQQQQQQQQQQQQQQQQQQQQ 547 >gi|41872374 polo-like kinase 3 [Homo sapiens] Length = 646 Score = 30.4 bits (67), Expect = 8.3 Identities = 29/101 (28%), Positives = 42/101 (41%), Gaps = 10/101 (9%) Query: 746 RRMMSVYNHVLEEVESLNRK---YTPVSYMHTACLCNAIIALLKVPLSFQRYFFQKLQST 802 RR+ ++N S NRK Y P S H + A+ L+ L RYF ++ Sbjct: 483 RRVAVLFNDGTHMALSANRKTVHYNPTSTKHFSFSVGAVPRALQPQLGILRYFASYMEQH 542 Query: 803 SIKLALSPSPRN---PAEPIAVQ----NNQQLALKVEGVVQ 836 +K PS PA P+ +Q + L L +G VQ Sbjct: 543 LMKGGDLPSVEEVEVPAPPLLLQWVKTDQALLMLFSDGTVQ 583 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.319 0.131 0.370 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 31,830,744 Number of Sequences: 37866 Number of extensions: 1253515 Number of successful extensions: 5524 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 10 Number of HSP's successfully gapped in prelim test: 24 Number of HSP's that attempted gapping in prelim test: 5231 Number of HSP's gapped (non-prelim): 247 length of query: 962 length of database: 18,247,518 effective HSP length: 112 effective length of query: 850 effective length of database: 14,006,526 effective search space: 11905547100 effective search space used: 11905547100 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.