Guide to the Human Genome
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Search of human proteins with 7657218

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7657218 bromodomain-containing protein 4 isoform short [Homo
sapiens]
         (722 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7657218 bromodomain-containing protein 4 isoform short [Homo ...  1467   0.0  
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ...  1461   0.0  
gi|11067749 bromodomain containing protein 3 [Homo sapiens]           751   0.0  
gi|164419758 bromodomain containing 2 [Homo sapiens]                  731   0.0  
gi|4826806 bromodomain containing 2 [Homo sapiens]                    731   0.0  
gi|46399200 testis-specific bromodomain protein [Homo sapiens]        586   e-167
gi|46399198 testis-specific bromodomain protein [Homo sapiens]        586   e-167
gi|50345997 E1A binding protein p300 [Homo sapiens]                   106   9e-23
gi|119943102 CREB binding protein isoform b [Homo sapiens]             96   2e-19
gi|119943104 CREB binding protein isoform a [Homo sapiens]             96   2e-19
gi|40805843 K(lysine) acetyltransferase 2B [Homo sapiens]              89   1e-17
gi|148612882 cat eye syndrome chromosome region, candidate 2 [Ho...    84   4e-16
gi|38788260 bromodomain PHD finger transcription factor isoform ...    83   1e-15
gi|38788274 bromodomain PHD finger transcription factor isoform ...    83   1e-15
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     82   1e-15
gi|153791535 general control of amino acid synthesis 5-like 2 [H...    77   4e-14
gi|47419911 transcriptional intermediary factor 1 alpha isoform ...    75   3e-13
gi|47419909 transcriptional intermediary factor 1 alpha isoform ...    75   3e-13
gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo...    73   8e-13
gi|116284392 mucin 2 precursor [Homo sapiens]                          73   1e-12
gi|110349719 titin isoform N2-A [Homo sapiens]                         71   3e-12
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo...    70   7e-12
gi|237649104 bromodomain containing 9 isoform 1 [Homo sapiens]         69   1e-11
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa...    69   2e-11
gi|91176325 bromodomain adjacent to zinc finger domain, 2A [Homo...    68   3e-11
gi|153792074 proline rich 12 [Homo sapiens]                            68   3e-11
gi|14670392 bromodomain adjacent to zinc finger domain, 1B [Homo...    67   4e-11
gi|34452709 bromodomain containing 8 isoform 3 [Homo sapiens]          67   4e-11
gi|34452707 bromodomain containing 8 isoform 2 [Homo sapiens]          67   4e-11
gi|34452705 bromodomain containing 8 isoform 1 [Homo sapiens]          67   4e-11

>gi|7657218 bromodomain-containing protein 4 isoform short [Homo
           sapiens]
          Length = 722

 Score = 1467 bits (3799), Expect = 0.0
 Identities = 722/722 (100%), Positives = 722/722 (100%)

Query: 1   MSAESGPGTRLRNLPVMGDGLETSQMSTTQAQAQPQPANAASTNPPPPETSNPNKPKRQT 60
           MSAESGPGTRLRNLPVMGDGLETSQMSTTQAQAQPQPANAASTNPPPPETSNPNKPKRQT
Sbjct: 1   MSAESGPGTRLRNLPVMGDGLETSQMSTTQAQAQPQPANAASTNPPPPETSNPNKPKRQT 60

Query: 61  NQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYW 120
           NQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYW
Sbjct: 61  NQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYW 120

Query: 121 NAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEETEIMIVQAKGRG 180
           NAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEETEIMIVQAKGRG
Sbjct: 121 NAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEETEIMIVQAKGRG 180

Query: 181 RGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMT 240
           RGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMT
Sbjct: 181 RGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMT 240

Query: 241 VVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTI 300
           VVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTI
Sbjct: 241 VVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTI 300

Query: 301 DPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQLKCCSGI 360
           DPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQLKCCSGI
Sbjct: 301 DPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQLKCCSGI 360

Query: 361 LKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGA 420
           LKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGA
Sbjct: 361 LKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGA 420

Query: 421 DVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPPPTKVV 480
           DVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPPPTKVV
Sbjct: 421 DVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPPPTKVV 480

Query: 481 APPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKE 540
           APPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKE
Sbjct: 481 APPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKE 540

Query: 541 KDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYE 600
           KDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYE
Sbjct: 541 KDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYE 600

Query: 601 SEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLK 660
           SEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLK
Sbjct: 601 SEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLK 660

Query: 661 PSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETG 720
           PSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETG
Sbjct: 661 PSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETG 720

Query: 721 PA 722
           PA
Sbjct: 721 PA 722


>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
           sapiens]
          Length = 1362

 Score = 1461 bits (3782), Expect = 0.0
 Identities = 719/719 (100%), Positives = 719/719 (100%)

Query: 1   MSAESGPGTRLRNLPVMGDGLETSQMSTTQAQAQPQPANAASTNPPPPETSNPNKPKRQT 60
           MSAESGPGTRLRNLPVMGDGLETSQMSTTQAQAQPQPANAASTNPPPPETSNPNKPKRQT
Sbjct: 1   MSAESGPGTRLRNLPVMGDGLETSQMSTTQAQAQPQPANAASTNPPPPETSNPNKPKRQT 60

Query: 61  NQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYW 120
           NQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYW
Sbjct: 61  NQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYW 120

Query: 121 NAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEETEIMIVQAKGRG 180
           NAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEETEIMIVQAKGRG
Sbjct: 121 NAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEETEIMIVQAKGRG 180

Query: 181 RGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMT 240
           RGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMT
Sbjct: 181 RGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMT 240

Query: 241 VVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTI 300
           VVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTI
Sbjct: 241 VVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTI 300

Query: 301 DPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQLKCCSGI 360
           DPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQLKCCSGI
Sbjct: 301 DPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQLKCCSGI 360

Query: 361 LKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGA 420
           LKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGA
Sbjct: 361 LKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGA 420

Query: 421 DVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPPPTKVV 480
           DVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPPPTKVV
Sbjct: 421 DVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPPPTKVV 480

Query: 481 APPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKE 540
           APPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKE
Sbjct: 481 APPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKE 540

Query: 541 KDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYE 600
           KDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYE
Sbjct: 541 KDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYE 600

Query: 601 SEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLK 660
           SEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLK
Sbjct: 601 SEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLK 660

Query: 661 PSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSET 719
           PSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSET
Sbjct: 661 PSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSET 719



 Score = 64.7 bits (156), Expect = 3e-10
 Identities = 103/521 (19%), Positives = 176/521 (33%), Gaps = 123/521 (23%)

Query: 189  AKPGVSTVPNTTQASTPPQ-----------TQTPQPNPPPVQATPH-----------PFP 226
            A P   + P+   A+ PP+           TQTP    PP+   P            P  
Sbjct: 865  ALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLT 924

Query: 227  AVTPDLIVQTPVMTVVPPQPL--------QTPPPVPPQP----------QPPPAPAPQP- 267
            ++   L +Q  +  V PP PL        Q PPP+PP P          QPPP P PQP 
Sbjct: 925  SMQMQLYLQ-QLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQ 983

Query: 268  ----VQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEP----KTTKLG 319
                 Q  PP      QP++    +++      P    P H PP   P P    K  ++ 
Sbjct: 984  PPPQQQHQPPPRPVHLQPMQFSTHIQQ---PPPPQGQQPPHPPPGQQPPPPQPAKPQQVI 1040

Query: 320  QRRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQLKCCSGILKEMFAKKHAAYAWPFYKP 379
            Q   S R  K         ++ P+P         L   S  + +  +  H +      +P
Sbjct: 1041 QHHHSPRHHKSDPYSTGHLREAPSP---------LMIHSPQMSQFQSLTHQSPPQQNVQP 1091

Query: 380  VDVEALGLHDYCDIIKHPMDMSTIK-SKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHE 438
               E          +  P  +  +K  K+ +   R            FS   +  PP H 
Sbjct: 1092 KKQELRAAS-----VVQPQPLVVVKEEKIHSPIIRSEP---------FSPSLRPEPPKHP 1137

Query: 439  VVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDS------ 492
                A             +P  PE   V V  P + PP +   PP + D           
Sbjct: 1138 ESIKAP----------VHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQEPKTP 1187

Query: 493  --------------------------SSDSDSSTDDSEE-ERAQRLAELQEQLKAVHEQL 525
                                      SS + SS+D  E+  RA R  E +E+      + 
Sbjct: 1188 VAPKKDLKIKNMGSWASLVQKHPTTPSSTAKSSSDSFEQFRRAAREKEEREKALKAQAEH 1247

Query: 526  AALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSK 585
            A   + +  + + + ++ ++  ++  +  EE    ++ + ++   ++ ++   + +  + 
Sbjct: 1248 AEKEKERLRQERMRSREDEDALEQARRAHEEARRRQEQQQQQRQEQQQQQQQQAAAVAAA 1307

Query: 586  KEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQ---LSLDIN 623
              P    S+P    + + E   K      +R+    ++D+N
Sbjct: 1308 ATPQAQSSQPQSMLDQQRELARKREQERRRREAMAATIDMN 1348



 Score = 53.9 bits (128), Expect = 5e-07
 Identities = 48/168 (28%), Positives = 66/168 (39%), Gaps = 30/168 (17%)

Query: 206 PQTQTPQPNP-PPVQATPHPFPAVTPDLIVQTPVMTVVPPQ----PLQTPPPVPPQPQPP 260
           PQ + P   P PP  +TP   P +    +V  P +    PQ    P      +PP+P  P
Sbjct: 831 PQPELPPHLPQPPEHSTP---PHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARP 887

Query: 261 PA--PA-------PQPVQSHPPIIAAT----PQPVKTKKGVK----RKADTTTPTTIDPI 303
           PA  PA       PQP  + PP +       P P  T   ++    +      PT + P 
Sbjct: 888 PAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPS 947

Query: 304 -----HEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEK 346
                  PP LPP P  +   Q ++   P  PP+   P  QQH  P +
Sbjct: 948 VKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPR 995



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 54/209 (25%), Positives = 82/209 (39%), Gaps = 20/209 (9%)

Query: 158 LQKINELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPP 217
           L+K  +   E+ +++   +K +G    E+ ++    S+    ++    P+++  +   P 
Sbjct: 675 LRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETEMAPKSK--KKGHPG 732

Query: 218 VQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPP----QPQPPPAPAPQPVQ---- 269
            +   H             PV    PP P Q PPP PP    QP PPP P   P Q    
Sbjct: 733 REQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPA 792

Query: 270 --SHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEP-PSLPPEPKTTKLGQRRESSR 326
             S PP   AT  PV   +      D     T   +H P P LPP      L Q  E S 
Sbjct: 793 MKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPH-----LPQPPEHST 847

Query: 327 PVKPPKKDV--PDSQQHPAPEKSSKVSEQ 353
           P    +  V  P +  +  P++ S+ S +
Sbjct: 848 PPHLNQHAVVSPPALHNALPQQPSRPSNR 876



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 76/426 (17%), Positives = 148/426 (34%), Gaps = 88/426 (20%)

Query: 253 VPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTT------------- 299
           +P +P+ P      P    P  + A P    +       +D++T  +             
Sbjct: 457 MPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQE 516

Query: 300 -IDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPK----KDVPDSQQHPAPEKSSKVSEQL 354
            +  +HE  +   +P+  K  ++ +  +  K  K    ++V ++++  A E   K +++ 
Sbjct: 517 QLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKN 576

Query: 355 KCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRD 414
              +  + +       +   P Y+  + +      Y +  +  +D++ +  +   R    
Sbjct: 577 NSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHI 636

Query: 415 AQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEM--------RFAKMPDEPEEPVV 466
            Q     ++         NP + E+     K   + E+        R  + P   +  V+
Sbjct: 637 IQSREPSLK-------NSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVI 689

Query: 467 AVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLA 526
           A SS       K+    SS   SS  SS SDS  +DSE E A                  
Sbjct: 690 AGSS-------KMKGFSSSESESSSESSSSDS--EDSETEMAP----------------- 723

Query: 527 ALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKK 586
                   K KKK    +E+KK  H   +++++      ++PPP                
Sbjct: 724 --------KSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPP--------------- 760

Query: 587 EPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKN 646
              P +  PPP  + +++    P      +Q +  +   P   +   V ++   EP L  
Sbjct: 761 ---PQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVL---EPQLPG 814

Query: 647 SNPDEI 652
           S  D I
Sbjct: 815 SVFDPI 820


>gi|11067749 bromodomain containing protein 3 [Homo sapiens]
          Length = 726

 Score =  751 bits (1939), Expect = 0.0
 Identities = 422/742 (56%), Positives = 490/742 (66%), Gaps = 88/742 (11%)

Query: 37  PANAASTNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPD 96
           PA     NPPPPE SNP+KP R+TNQLQY+  VV+KTLWKHQFAWPF QPVDA+KLNLPD
Sbjct: 13  PATPGPVNPPPPEVSNPSKPGRKTNQLQYMQNVVVKTLWKHQFAWPFYQPVDAIKLNLPD 72

Query: 97  YYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKL 156
           Y+KIIK PMDMGTIKKRLENNYYW+A EC+QDFNTMFTNCYIYNKP DDIVLMA+ALEK+
Sbjct: 73  YHKIIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKI 132

Query: 157 FLQKINELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPP 216
           FLQK+ ++P EE E++    KG+GR +   G    G   V     +S  P T   Q  PP
Sbjct: 133 FLQKVAQMPQEEVELLPPAPKGKGR-KPAAGAQSAGTQQV--AAVSSVSPATPF-QSVPP 188

Query: 217 PVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIA 276
            V  TP         +I  TPV T+       T  PVPP   PPP     P     P++ 
Sbjct: 189 TVSQTP---------VIAATPVPTITAN---VTSVPVPPAAAPPP-----PATPIVPVVP 231

Query: 277 ATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPP---EPKTTKLGQRRES-SRPVKPPK 332
            TP PV  KKGVKRKADTTTPTT          PP   +PK  K+  RRES  RP+KPPK
Sbjct: 232 PTP-PVVKKKGVKRKADTTTPTTSAITASRSESPPPLSDPKQAKVVARRESGGRPIKPPK 290

Query: 333 KDVPDSQQHPAPEKSSKVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCD 392
           KD+ D +      K  K+SE L+ C  IL+EM +KKHAAYAWPFYKPVD EAL LHDY D
Sbjct: 291 KDLEDGEVPQHAGKKGKLSEHLRYCDSILREMLSKKHAAYAWPFYKPVDAEALELHDYHD 350

Query: 393 IIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEM 452
           IIKHPMD+ST+K K++ REY DAQ F ADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEM
Sbjct: 351 IIKHPMDLSTVKRKMDGREYPDAQGFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEM 410

Query: 453 RFAKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLA 512
           RFAKMPDEP      V +PA+P P   +    +  S S   S SDS + DSEEERA RLA
Sbjct: 411 RFAKMPDEP------VEAPALPAPAAPMVSKGAESSRSSEESSSDSGSSDSEEERATRLA 464

Query: 513 ELQEQLKAVHEQLAALSQPQQNKPKK------KEKDKKEKKKEKHKRKEEVEENKKSK-- 564
           ELQEQLKAVHEQLAALSQ   NKPKK      KEK KK+K+KEK K K + EE KK+K  
Sbjct: 465 ELQEQLKAVHEQLAALSQAPVNKPKKKKEKKEKEKKKKDKEKEKEKHKVKAEEEKKAKVA 524

Query: 565 --AKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDI 622
             AK+   KK     ++++  + ++      +   +Y+SEEE++  PMSY+EKRQLSLDI
Sbjct: 525 PPAKQAQQKKAPAKKANSTTTAGRQLKKGGKQASASYDSEEEEEGLPMSYDEKRQLSLDI 584

Query: 623 NKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKK-RKP 681
           N+LPGEKLGRVVHIIQSREPSL++SNPDEIEIDFETLKP+TLRELERYV SCL+KK RKP
Sbjct: 585 NRLPGEKLGRVVHIIQSREPSLRDSNPDEIEIDFETLKPTTLRELERYVKSCLQKKQRKP 644

Query: 682 -----------------QAEKVDV---------------------------IAGSSKMKG 697
                            Q +K ++                             G S++  
Sbjct: 645 FSASGKKQAAKSKEELAQEKKKELEKRLQDVSGQLSSSKKPARKEKPGSAPSGGPSRLSS 704

Query: 698 FSSSESESSSES-SSSDSEDSE 718
            SSSES SSS S SSSDS DSE
Sbjct: 705 SSSSESGSSSSSGSSSDSSDSE 726


>gi|164419758 bromodomain containing 2 [Homo sapiens]
          Length = 801

 Score =  731 bits (1887), Expect = 0.0
 Identities = 429/815 (52%), Positives = 518/815 (63%), Gaps = 139/815 (17%)

Query: 5   SGPGTRLRNLPVMGDGLETSQMSTTQAQAQPQPANAASTNPPPPETSNPNKPKRQTNQLQ 64
           + PG R+R   ++ +G E+  M++  A  Q  PAN     PPPPE SNP KP R TNQLQ
Sbjct: 27  AAPGKRIRKPSLLYEGFESPTMASVPA-LQLTPAN-----PPPPEVSNPKKPGRVTNQLQ 80

Query: 65  YLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQE 124
           YL +VV+K LWKHQFAWPF+QPVDAVKL LPDY+KIIK PMDMGTIK+RLENNYYW A E
Sbjct: 81  YLHKVVMKALWKHQFAWPFRQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYWAASE 140

Query: 125 CIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEETEIMIVQAKGRGR--- 181
           C+QDFNTMFTNCYIYNKP DDIVLMA+ LEK+FLQK+  +P EE E+++   K   +   
Sbjct: 141 CMQDFNTMFTNCYIYNKPTDDIVLMAQTLEKIFLQKVASMPQEEQELVVTIPKNSHKKGA 200

Query: 182 ------GRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQ 235
                 G   +    P VS+V +T   + PP+       P  V   PHP        ++ 
Sbjct: 201 KLAALQGSVTSAHQVPAVSSVSHTALYTPPPEI------PTTVLNIPHP-------SVIS 247

Query: 236 TPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTT 295
           +P++  +        PP+      PPA                 QP+  KKGVKRKADTT
Sbjct: 248 SPLLKSLH----SAGPPLLAVTAAPPA-----------------QPLAKKKGVKRKADTT 286

Query: 296 TPT-TIDPIHEPPSLPP---EPKTTKL-GQRRESSRPVKPPKKDVPDSQQHPAPEKSSKV 350
           TPT T       P+ PP   EPK  +L   RRES RP+KPP+KD+PDSQQ     K  K+
Sbjct: 287 TPTPTAILAPGSPASPPGSLEPKAARLPPMRRESGRPIKPPRKDLPDSQQQHQSSKKGKL 346

Query: 351 SEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAR 410
           SEQLK C+GILKE+ +KKHAAYAWPFYKPVD  ALGLHDY DIIKHPMD+ST+K K+E R
Sbjct: 347 SEQLKHCNGILKELLSKKHAAYAWPFYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENR 406

Query: 411 EYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSS 470
           +YRDAQEF ADVRLMFSNCYKYNPPDH+VVAMARKLQDVFE R+AKMPDEP EP     S
Sbjct: 407 DYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDVFEFRYAKMPDEPLEPGPLPVS 466

Query: 471 PAVPPP-TKVVAPPSSSDSSSDSSS------------DSDSSTDDSEEERAQRLAELQEQ 517
            A+PP   K  +  SS +SSS+SSS            + +S + DSEEERA RLAELQEQ
Sbjct: 467 TAMPPGLAKSSSESSSEESSSESSSEEEEEEDEEDEEEEESESSDSEEERAHRLAELQEQ 526

Query: 518 LKAVHEQLAALSQPQQNKPKKKEKDKKEKKK---EKHKRKEEVEENKKS-KAKEPP-PKK 572
           L+AVHEQLAALSQ   +KPK+K + K++KKK   EKH+ +   +E+ K  +A  PP PKK
Sbjct: 527 LRAVHEQLAALSQGPISKPKRKREKKEKKKKRKAEKHRGRAGADEDDKGPRAPRPPQPKK 586

Query: 573 TKKNNSSNSNVSKKEPA---------------PMKSKPP--PT-YESEEEDKCKPMSYEE 614
           +KK + S    +   P+                 K+ PP  PT Y+SEEE++ +PMSY+E
Sbjct: 587 SKKASGSGGGSAALGPSGFGPSGGSGTKLPKKATKTAPPALPTGYDSEEEEESRPMSYDE 646

Query: 615 KRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSC 674
           KRQLSLDINKLPGEKLGRVVHIIQ+REPSL++SNP+EIEIDFETLKPSTLRELERYV SC
Sbjct: 647 KRQLSLDINKLPGEKLGRVVHIIQAREPSLRDSNPEEIEIDFETLKPSTLRELERYVLSC 706

Query: 675 LRKK-RKPQAEKVDV---------------------IAGS-------------------- 692
           LRKK RKP   K  V                     ++G                     
Sbjct: 707 LRKKPRKPYTIKKPVGKTKEELALEKKRELEKRLQDVSGQLNSTKKPPKKANEKTESSSA 766

Query: 693 -----SKMKGFSSS--ESESSSESSSSDSEDSETG 720
                S++   SSS   S SSS SSSSD+ DS++G
Sbjct: 767 QQVAVSRLSASSSSSDSSSSSSSSSSSDTSDSDSG 801


>gi|4826806 bromodomain containing 2 [Homo sapiens]
          Length = 801

 Score =  731 bits (1887), Expect = 0.0
 Identities = 429/815 (52%), Positives = 518/815 (63%), Gaps = 139/815 (17%)

Query: 5   SGPGTRLRNLPVMGDGLETSQMSTTQAQAQPQPANAASTNPPPPETSNPNKPKRQTNQLQ 64
           + PG R+R   ++ +G E+  M++  A  Q  PAN     PPPPE SNP KP R TNQLQ
Sbjct: 27  AAPGKRIRKPSLLYEGFESPTMASVPA-LQLTPAN-----PPPPEVSNPKKPGRVTNQLQ 80

Query: 65  YLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQE 124
           YL +VV+K LWKHQFAWPF+QPVDAVKL LPDY+KIIK PMDMGTIK+RLENNYYW A E
Sbjct: 81  YLHKVVMKALWKHQFAWPFRQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYWAASE 140

Query: 125 CIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEETEIMIVQAKGRGR--- 181
           C+QDFNTMFTNCYIYNKP DDIVLMA+ LEK+FLQK+  +P EE E+++   K   +   
Sbjct: 141 CMQDFNTMFTNCYIYNKPTDDIVLMAQTLEKIFLQKVASMPQEEQELVVTIPKNSHKKGA 200

Query: 182 ------GRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQ 235
                 G   +    P VS+V +T   + PP+       P  V   PHP        ++ 
Sbjct: 201 KLAALQGSVTSAHQVPAVSSVSHTALYTPPPEI------PTTVLNIPHP-------SVIS 247

Query: 236 TPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTT 295
           +P++  +        PP+      PPA                 QP+  KKGVKRKADTT
Sbjct: 248 SPLLKSLH----SAGPPLLAVTAAPPA-----------------QPLAKKKGVKRKADTT 286

Query: 296 TPT-TIDPIHEPPSLPP---EPKTTKL-GQRRESSRPVKPPKKDVPDSQQHPAPEKSSKV 350
           TPT T       P+ PP   EPK  +L   RRES RP+KPP+KD+PDSQQ     K  K+
Sbjct: 287 TPTPTAILAPGSPASPPGSLEPKAARLPPMRRESGRPIKPPRKDLPDSQQQHQSSKKGKL 346

Query: 351 SEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAR 410
           SEQLK C+GILKE+ +KKHAAYAWPFYKPVD  ALGLHDY DIIKHPMD+ST+K K+E R
Sbjct: 347 SEQLKHCNGILKELLSKKHAAYAWPFYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENR 406

Query: 411 EYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSS 470
           +YRDAQEF ADVRLMFSNCYKYNPPDH+VVAMARKLQDVFE R+AKMPDEP EP     S
Sbjct: 407 DYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDVFEFRYAKMPDEPLEPGPLPVS 466

Query: 471 PAVPPP-TKVVAPPSSSDSSSDSSS------------DSDSSTDDSEEERAQRLAELQEQ 517
            A+PP   K  +  SS +SSS+SSS            + +S + DSEEERA RLAELQEQ
Sbjct: 467 TAMPPGLAKSSSESSSEESSSESSSEEEEEEDEEDEEEEESESSDSEEERAHRLAELQEQ 526

Query: 518 LKAVHEQLAALSQPQQNKPKKKEKDKKEKKK---EKHKRKEEVEENKKS-KAKEPP-PKK 572
           L+AVHEQLAALSQ   +KPK+K + K++KKK   EKH+ +   +E+ K  +A  PP PKK
Sbjct: 527 LRAVHEQLAALSQGPISKPKRKREKKEKKKKRKAEKHRGRAGADEDDKGPRAPRPPQPKK 586

Query: 573 TKKNNSSNSNVSKKEPA---------------PMKSKPP--PT-YESEEEDKCKPMSYEE 614
           +KK + S    +   P+                 K+ PP  PT Y+SEEE++ +PMSY+E
Sbjct: 587 SKKASGSGGGSAALGPSGFGPSGGSGTKLPKKATKTAPPALPTGYDSEEEEESRPMSYDE 646

Query: 615 KRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSC 674
           KRQLSLDINKLPGEKLGRVVHIIQ+REPSL++SNP+EIEIDFETLKPSTLRELERYV SC
Sbjct: 647 KRQLSLDINKLPGEKLGRVVHIIQAREPSLRDSNPEEIEIDFETLKPSTLRELERYVLSC 706

Query: 675 LRKK-RKPQAEKVDV---------------------IAGS-------------------- 692
           LRKK RKP   K  V                     ++G                     
Sbjct: 707 LRKKPRKPYTIKKPVGKTKEELALEKKRELEKRLQDVSGQLNSTKKPPKKANEKTESSSA 766

Query: 693 -----SKMKGFSSS--ESESSSESSSSDSEDSETG 720
                S++   SSS   S SSS SSSSD+ DS++G
Sbjct: 767 QQVAVSRLSASSSSSDSSSSSSSSSSSDTSDSDSG 801


>gi|46399200 testis-specific bromodomain protein [Homo sapiens]
          Length = 947

 Score =  586 bits (1510), Expect = e-167
 Identities = 352/742 (47%), Positives = 437/742 (58%), Gaps = 135/742 (18%)

Query: 35  PQPANAASTNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNL 94
           P    A   NPPPPE  N  K  R TNQLQYL +VVLK LWKH F+WPFQ+PVDAVKL L
Sbjct: 4   PSRQTAIIVNPPPPEYINTKKNGRLTNQLQYLQKVVLKDLWKHSFSWPFQRPVDAVKLQL 63

Query: 95  PDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALE 154
           PDYY IIK PMD+ TIKKRLEN YY  A ECI+DFNTMF+NCY+YNKPGDDIVLMA+ALE
Sbjct: 64  PDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQALE 123

Query: 155 KLFLQKINELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPN 214
           KLF+QK++++P EE  + + +       R + GT                       Q N
Sbjct: 124 KLFMQKLSQMPQEEQVVGVKE-------RIKKGT-----------------------QQN 153

Query: 215 PPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPI 274
                A     P+ T  +  Q  + +V P   +                +P  V     +
Sbjct: 154 IAVSSAKEKSSPSATEKVFKQQEIPSVFPKTSI----------------SPLNVVQGASV 197

Query: 275 IAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKP--PK 332
            +++    +  KGVKRKADTTTP T   +       P        ++  +  P+K   PK
Sbjct: 198 NSSSQTAAQVTKGVKRKADTTTPAT-SAVKASSEFSPT-----FTEKSVALPPIKENMPK 251

Query: 333 KDVPDSQQHPAPEKSSKVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCD 392
             +PDSQQ     K+ KV+EQL+ CS ILKEM AKKH +YAWPFY PVDV ALGLH+Y D
Sbjct: 252 NVLPDSQQQYNVVKTVKVTEQLRHCSEILKEMLAKKHFSYAWPFYNPVDVNALGLHNYYD 311

Query: 393 IIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEM 452
           ++K+PMD+ TIK K++ +EY+DA +F ADVRLMF NCYKYNPPDHEVV MAR LQDVFE 
Sbjct: 312 VVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVVTMARMLQDVFET 371

Query: 453 RFAKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLA 512
            F+K+P EP E     S P     T  +   +  ++++++SS+ +SS DDSE+ER +RLA
Sbjct: 372 HFSKIPIEPVE-----SMPLCYIKTD-ITETTGRENTNEASSEGNSS-DDSEDERVKRLA 424

Query: 513 ELQEQLKAVHEQLAALSQ-PQQNKPKKKEKDKKEKKKEK------HKRKEEVEENKKSKA 565
           +LQEQLKAVH+QL  LSQ P +   KKKEK KKEKKKEK      + RK   +   K K+
Sbjct: 425 KLQEQLKAVHQQLQVLSQVPFRKLNKKKEKSKKEKKKEKVNNSNENPRKMCEQMRLKEKS 484

Query: 566 KEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKL 625
           K   PKK K+                        +SE+ED  KPM+Y+EKRQLSL+INKL
Sbjct: 485 KRNQPKKRKQQFIG-------------------LKSEDEDNAKPMNYDEKRQLSLNINKL 525

Query: 626 PGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKK-RKPQAE 684
           PG+KLGRVVHIIQSREPSL NSNPDEIEIDFETLK STLRELE+YV++CLRK+  KP A+
Sbjct: 526 PGDKLGRVVHIIQSREPSLSNSNPDEIEIDFETLKASTLRELEKYVSACLRKRPLKPPAK 585

Query: 685 KV--------------------DV---------------------------IAGSSKMKG 697
           K+                    DV                           ++ SS    
Sbjct: 586 KIMMSKEELHSQKKQELEKRLLDVNNQLNSRKRQTKSDKTQPSKAVENVSRLSESSSSSS 645

Query: 698 FSSSESESSSESSSSDSEDSET 719
            SS    SSS+ SSSDS DSE+
Sbjct: 646 SSSESESSSSDLSSSDSSDSES 667


>gi|46399198 testis-specific bromodomain protein [Homo sapiens]
          Length = 947

 Score =  586 bits (1510), Expect = e-167
 Identities = 352/742 (47%), Positives = 437/742 (58%), Gaps = 135/742 (18%)

Query: 35  PQPANAASTNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNL 94
           P    A   NPPPPE  N  K  R TNQLQYL +VVLK LWKH F+WPFQ+PVDAVKL L
Sbjct: 4   PSRQTAIIVNPPPPEYINTKKNGRLTNQLQYLQKVVLKDLWKHSFSWPFQRPVDAVKLQL 63

Query: 95  PDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALE 154
           PDYY IIK PMD+ TIKKRLEN YY  A ECI+DFNTMF+NCY+YNKPGDDIVLMA+ALE
Sbjct: 64  PDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQALE 123

Query: 155 KLFLQKINELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPN 214
           KLF+QK++++P EE  + + +       R + GT                       Q N
Sbjct: 124 KLFMQKLSQMPQEEQVVGVKE-------RIKKGT-----------------------QQN 153

Query: 215 PPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPI 274
                A     P+ T  +  Q  + +V P   +                +P  V     +
Sbjct: 154 IAVSSAKEKSSPSATEKVFKQQEIPSVFPKTSI----------------SPLNVVQGASV 197

Query: 275 IAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKP--PK 332
            +++    +  KGVKRKADTTTP T   +       P        ++  +  P+K   PK
Sbjct: 198 NSSSQTAAQVTKGVKRKADTTTPAT-SAVKASSEFSPT-----FTEKSVALPPIKENMPK 251

Query: 333 KDVPDSQQHPAPEKSSKVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCD 392
             +PDSQQ     K+ KV+EQL+ CS ILKEM AKKH +YAWPFY PVDV ALGLH+Y D
Sbjct: 252 NVLPDSQQQYNVVKTVKVTEQLRHCSEILKEMLAKKHFSYAWPFYNPVDVNALGLHNYYD 311

Query: 393 IIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEM 452
           ++K+PMD+ TIK K++ +EY+DA +F ADVRLMF NCYKYNPPDHEVV MAR LQDVFE 
Sbjct: 312 VVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVVTMARMLQDVFET 371

Query: 453 RFAKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLA 512
            F+K+P EP E     S P     T  +   +  ++++++SS+ +SS DDSE+ER +RLA
Sbjct: 372 HFSKIPIEPVE-----SMPLCYIKTD-ITETTGRENTNEASSEGNSS-DDSEDERVKRLA 424

Query: 513 ELQEQLKAVHEQLAALSQ-PQQNKPKKKEKDKKEKKKEK------HKRKEEVEENKKSKA 565
           +LQEQLKAVH+QL  LSQ P +   KKKEK KKEKKKEK      + RK   +   K K+
Sbjct: 425 KLQEQLKAVHQQLQVLSQVPFRKLNKKKEKSKKEKKKEKVNNSNENPRKMCEQMRLKEKS 484

Query: 566 KEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKL 625
           K   PKK K+                        +SE+ED  KPM+Y+EKRQLSL+INKL
Sbjct: 485 KRNQPKKRKQQFIG-------------------LKSEDEDNAKPMNYDEKRQLSLNINKL 525

Query: 626 PGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKK-RKPQAE 684
           PG+KLGRVVHIIQSREPSL NSNPDEIEIDFETLK STLRELE+YV++CLRK+  KP A+
Sbjct: 526 PGDKLGRVVHIIQSREPSLSNSNPDEIEIDFETLKASTLRELEKYVSACLRKRPLKPPAK 585

Query: 685 KV--------------------DV---------------------------IAGSSKMKG 697
           K+                    DV                           ++ SS    
Sbjct: 586 KIMMSKEELHSQKKQELEKRLLDVNNQLNSRKRQTKSDKTQPSKAVENVSRLSESSSSSS 645

Query: 698 FSSSESESSSESSSSDSEDSET 719
            SS    SSS+ SSSDS DSE+
Sbjct: 646 SSSESESSSSDLSSSDSSDSES 667


>gi|50345997 E1A binding protein p300 [Homo sapiens]
          Length = 2414

 Score =  106 bits (264), Expect = 9e-23
 Identities = 80/273 (29%), Positives = 122/273 (44%), Gaps = 20/273 (7%)

Query: 197  PNTTQASTPPQTQTPQPNPPPVQATP-------HPFPAVTPDLIVQTPVMTVVPPQPLQ- 248
            P   Q  TPP TQ PQ   P + A P        P    +    V TP   ++PPQP   
Sbjct: 880  PPPRQTPTPPTTQLPQQVQPSLPAAPSADQPQQQPRSQQSTAASVPTPTAPLLPPQPATP 939

Query: 249  -TPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDP--IHE 305
             + P V  + Q    P+    + +   IA      + K   K + D   P    P  I E
Sbjct: 940  LSQPAVSIEGQVSNPPSTSSTEVNSQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISE 999

Query: 306  PPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDS---QQHPAPEKSSKV----SEQLKCCS 358
                  + ++T+  +R    +     ++D P +   Q  PAP +S K      E  +   
Sbjct: 1000 SKVEDCKMESTETEERSTELKTEIKEEEDQPSTSATQSSPAPGQSKKKIFKPEELRQALM 1059

Query: 359  GILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEF 418
              L+ ++ +   +   PF +PVD + LG+ DY DI+K PMD+STIK KL+  +Y++  ++
Sbjct: 1060 PTLEALYRQDPESL--PFRQPVDPQLLGIPDYFDIVKSPMDLSTIKRKLDTGQYQEPWQY 1117

Query: 419  GADVRLMFSNCYKYNPPDHEVVAMARKLQDVFE 451
              D+ LMF+N + YN     V     KL +VFE
Sbjct: 1118 VDDIWLMFNNAWLYNRKTSRVYKYCSKLSEVFE 1150



 Score = 81.3 bits (199), Expect = 3e-15
 Identities = 47/163 (28%), Positives = 86/163 (52%), Gaps = 12/163 (7%)

Query: 23   TSQMSTTQAQAQPQPANAASTNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQ-FAW 81
            ++++ T   + + QP+ +A+ + P P  S   K   +  +L+  L   L+ L++    + 
Sbjct: 1016 STELKTEIKEEEDQPSTSATQSSPAPGQSK--KKIFKPEELRQALMPTLEALYRQDPESL 1073

Query: 82   PFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNK 141
            PF+QPVD   L +PDY+ I+K+PMD+ TIK++L+   Y    + + D   MF N ++YN+
Sbjct: 1074 PFRQPVDPQLLGIPDYFDIVKSPMDLSTIKRKLDTGQYQEPWQYVDDIWLMFNNAWLYNR 1133

Query: 142  PGDDIVLMAEALEKLFLQKINELPTEETEIMIVQAKGRGRGRK 184
                +      L ++F Q+I+          ++Q+ G   GRK
Sbjct: 1134 KTSRVYKYCSKLSEVFEQEIDP---------VMQSLGYCCGRK 1167



 Score = 57.4 bits (137), Expect = 5e-08
 Identities = 48/165 (29%), Positives = 65/165 (39%), Gaps = 39/165 (23%)

Query: 206 PQTQTPQPNPPPVQA---TPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQ---- 258
           PQ    Q +P PV +   TPH  P   P +  Q P  T +P  P+ TPP +PP PQ    
Sbjct: 823 PQPALHQNSPSPVPSRTPTPHHTP---PSIGAQQPPATTIPA-PVPTPPAMPPGPQSQAL 878

Query: 259 ---------PPPAPAPQPVQSHPPIIAATPQPVKTKKGVK-RKADTTTPTTIDPIHEPPS 308
                    PP    PQ VQ   P   +  QP +  +  +   A   TPT        P 
Sbjct: 879 HPPPRQTPTPPTTQLPQQVQPSLPAAPSADQPQQQPRSQQSTAASVPTPTA-------PL 931

Query: 309 LPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQ 353
           LPP+P T           P+  P   +     +P    S++V+ Q
Sbjct: 932 LPPQPAT-----------PLSQPAVSIEGQVSNPPSTSSTEVNSQ 965



 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 56/194 (28%), Positives = 70/194 (36%), Gaps = 38/194 (19%)

Query: 185 ETGTAKPGVSTVPNTTQASTP----PQTQTPQPN---------PPPVQATPHPFPAVTPD 231
           + G   P +   P   Q S      PQTQ P            P   QA        +  
Sbjct: 741 QPGALNPPMGYGPRMQQPSNQGQFLPQTQFPSQGMNVTNIPLAPSSGQAPVSQAQMSSSS 800

Query: 232 LIVQTPVMTVVPPQPL-------QTPPPVPPQPQPPPAPAPQPVQSH-PPIIAATPQPVK 283
             V +P+M   PP          Q P P   Q  P P P+  P   H PP I A   P  
Sbjct: 801 CPVNSPIM---PPGSQGSHIHCPQLPQPALHQNSPSPVPSRTPTPHHTPPSIGAQQPPAT 857

Query: 284 TKKGVKRKADTTTPTTIDP------IHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPD 337
           T       A   TP  + P      +H PP   P P TT+L Q+ + S P   P  D P 
Sbjct: 858 T-----IPAPVPTPPAMPPGPQSQALHPPPRQTPTPPTTQLPQQVQPSLPA-APSADQP- 910

Query: 338 SQQHPAPEKSSKVS 351
            QQ P  ++S+  S
Sbjct: 911 -QQQPRSQQSTAAS 923



 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 28/77 (36%), Positives = 30/77 (38%), Gaps = 5/77 (6%)

Query: 191  PGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTP 250
            P   T P   Q +TP   QTPQP   P    P+  P   P      PV         Q  
Sbjct: 1852 PATPTTPTGQQPTTP---QTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQ--GKAAGQVT 1906

Query: 251  PPVPPQPQPPPAPAPQP 267
            PP PPQ   PP P P P
Sbjct: 1907 PPTPPQTAQPPLPGPPP 1923



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 28/103 (27%), Positives = 35/103 (33%), Gaps = 16/103 (15%)

Query: 219  QATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAAT 278
            Q  P P PA               P  P    P  P  PQP   P P P  S PP +  T
Sbjct: 1845 QGLPSPTPAT--------------PTTPTGQQPTTPQTPQPTSQPQPTPPNSMPPYLPRT 1890

Query: 279  PQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQR 321
                   +G  + A   TP T     +PP   P P   ++  +
Sbjct: 1891 QAAGPVSQG--KAAGQVTPPTPPQTAQPPLPGPPPAAVEMAMQ 1931



 Score = 40.0 bits (92), Expect = 0.008
 Identities = 37/149 (24%), Positives = 64/149 (42%), Gaps = 16/149 (10%)

Query: 455  AKMPDEPEEPVVAVSSPA--VPPPTKVVAPPS-----SSDSSSDSSSDSDSSTDDSEEER 507
            A   D+P++   +  S A  VP PT  + PP      S  + S     S+  +  S E  
Sbjct: 904  APSADQPQQQPRSQQSTAASVPTPTAPLLPPQPATPLSQPAVSIEGQVSNPPSTSSTEVN 963

Query: 508  AQRLAELQEQLKAVHEQLAALSQPQ--QNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKA 565
            +Q +AE Q   +   E    + QP+    +P+   + K E  K +    EE     K++ 
Sbjct: 964  SQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISESKVEDCKMESTETEERSTELKTEI 1023

Query: 566  KEPPPKKTKKNNSSNSNVSKKEPAPMKSK 594
            KE       + +  +++ ++  PAP +SK
Sbjct: 1024 KE-------EEDQPSTSATQSSPAPGQSK 1045



 Score = 39.7 bits (91), Expect = 0.010
 Identities = 41/169 (24%), Positives = 66/169 (39%), Gaps = 13/169 (7%)

Query: 455  AKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSS--DSSSDSSSDSDSSTDDSEEERAQRLA 512
            A +P  P  P    S    PPP +   PP++        S   + S+    ++ R+Q   
Sbjct: 861  APVPTPPAMPPGPQSQALHPPPRQTPTPPTTQLPQQVQPSLPAAPSADQPQQQPRSQ--- 917

Query: 513  ELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKK 572
              Q    +V    A L  PQ   P  +     E +          E N ++ A++ P ++
Sbjct: 918  --QSTAASVPTPTAPLLPPQPATPLSQPAVSIEGQVSNPPSTSSTEVNSQAIAEKQPSQE 975

Query: 573  TKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYE-EKRQLSL 620
             K      + +   +P P  ++P    ES+ ED CK  S E E+R   L
Sbjct: 976  VK----MEAKMEVDQPEPADTQPEDISESKVED-CKMESTETEERSTEL 1019



 Score = 39.3 bits (90), Expect = 0.013
 Identities = 35/142 (24%), Positives = 64/142 (45%), Gaps = 11/142 (7%)

Query: 461  PEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKA 520
            P +P   +S PAV    +V  PPS+  SS++ +S + +    S+E + +   E       
Sbjct: 933  PPQPATPLSQPAVSIEGQVSNPPST--SSTEVNSQAIAEKQPSQEVKMEAKME------- 983

Query: 521  VHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSN 580
            V +   A +QP+     K E D K +  E  +R  E++   K +  +P    T+ + +  
Sbjct: 984  VDQPEPADTQPEDISESKVE-DCKMESTETEERSTELKTEIKEEEDQPSTSATQSSPAPG 1042

Query: 581  SNVSK-KEPAPMKSKPPPTYES 601
             +  K  +P  ++    PT E+
Sbjct: 1043 QSKKKIFKPEELRQALMPTLEA 1064



 Score = 39.3 bits (90), Expect = 0.013
 Identities = 29/87 (33%), Positives = 43/87 (49%), Gaps = 10/87 (11%)

Query: 206  PQTQTPQPNPPPVQA-TPHPFPAVTPDLI---VQTPVMTVVPPQPLQTPPPVPPQP--QP 259
            P   +PQ +  P QA +PH      P+ +   V++P   V  P+P   PP   P P  QP
Sbjct: 2275 PNPMSPQQHMLPNQAQSPHLQGQQIPNSLSNQVRSP-QPVPSPRPQSQPPHSSPSPRMQP 2333

Query: 260  PPAP---APQPVQSHPPIIAATPQPVK 283
             P+P   +PQ    HP ++AA   P++
Sbjct: 2334 QPSPHHVSPQTSSPHPGLVAAQANPME 2360



 Score = 37.7 bits (86), Expect = 0.038
 Identities = 20/54 (37%), Positives = 33/54 (61%), Gaps = 2/54 (3%)

Query: 537  KKKEKDKKEKKKEKHKRKEEVEENK--KSKAKEPPPKKTKKNNSSNSNVSKKEP 588
            K+ E++++E+K+E++   E  +  K     AK+   KKT KN SS S  +KK+P
Sbjct: 1518 KELEQEEEERKREENTSNESTDVTKGDSKNAKKKNNKKTSKNKSSLSRGNKKKP 1571



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 26/76 (34%), Positives = 32/76 (42%), Gaps = 6/76 (7%)

Query: 212  QPNPPPVQATPHPFPAVTPDL----IVQTPVMTVVPPQPLQTPPPV--PPQPQPPPAPAP 265
            QPNP   Q    P  A +P L    I  +    V  PQP+ +P P   PP   P P   P
Sbjct: 2274 QPNPMSPQQHMLPNQAQSPHLQGQQIPNSLSNQVRSPQPVPSPRPQSQPPHSSPSPRMQP 2333

Query: 266  QPVQSHPPIIAATPQP 281
            QP   H     ++P P
Sbjct: 2334 QPSPHHVSPQTSSPHP 2349


>gi|119943102 CREB binding protein isoform b [Homo sapiens]
          Length = 2404

 Score = 95.5 bits (236), Expect = 2e-19
 Identities = 84/304 (27%), Positives = 130/304 (42%), Gaps = 51/304 (16%)

Query: 185  ETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPP 244
            +T T  PG  +VP+ TQ  + P  Q         Q TP P   V P  +  TP  +   P
Sbjct: 859  QTPTPTPG--SVPSATQTQSTPTVQAAAQ----AQVTPQPQTPVQPPSVA-TPQSSQQQP 911

Query: 245  QPLQTPPPVPPQPQPPPA-----PAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTT 299
             P+   PP  P  Q   +     P P  V S       + QP      ++ K +T    T
Sbjct: 912  TPVHAQPPGTPLSQAAASIDNRVPTPSSVASAE---TNSQQPGPDVPVLEMKTETQAEDT 968

Query: 300  IDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPA------PEKSSKVSEQ 353
             +P  +P     EP++  + +  + +  VK  + D+ + +  P       PE   +V E+
Sbjct: 969  -EP--DPGESKGEPRSEMMEEDLQGASQVKE-ETDIAEQKSEPMEVDEKKPEVKVEVKEE 1024

Query: 354  LKCCSG---------------------ILKEMFAKKHAAY-----AWPFYKPVDVEALGL 387
             +  S                      + + +     A Y     + PF +PVD + LG+
Sbjct: 1025 EESSSNGTASQSTSPSQPRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGI 1084

Query: 388  HDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQ 447
             DY DI+K+PMD+STIK KL+  +Y++  ++  DV LMF+N + YN     V     KL 
Sbjct: 1085 PDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLA 1144

Query: 448  DVFE 451
            +VFE
Sbjct: 1145 EVFE 1148



 Score = 78.2 bits (191), Expect = 3e-14
 Identities = 43/159 (27%), Positives = 85/159 (53%), Gaps = 13/159 (8%)

Query: 30   QAQAQPQPANAASTNPPPPETSNPNKPKRQT---NQLQYLLRVVLKTLWKHQ-FAWPFQQ 85
            + + + +    +S+N    ++++P++P+++     +L+  L   L+ L++    + PF+Q
Sbjct: 1016 EVKVEVKEEEESSSNGTASQSTSPSQPRKKIFKPEELRQALMPTLEALYRQDPESLPFRQ 1075

Query: 86   PVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDD 145
            PVD   L +PDY+ I+K PMD+ TIK++L+   Y    + + D   MF N ++YN+    
Sbjct: 1076 PVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSR 1135

Query: 146  IVLMAEALEKLFLQKINELPTEETEIMIVQAKGRGRGRK 184
            +      L ++F Q+I+          ++Q+ G   GRK
Sbjct: 1136 VYKFCSKLAEVFEQEIDP---------VMQSLGYCCGRK 1165



 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 31/76 (40%), Positives = 35/76 (46%), Gaps = 9/76 (11%)

Query: 188  TAKPGVSTVPNTTQASTPPQTQTP-QPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQP 246
            +A PG  T     Q STP   Q P QP P PV  +P  FP+V        P  TV   +P
Sbjct: 1849 SAPPGTPT----QQPSTPQTPQPPAQPQPSPVSMSPAGFPSVART----QPPTTVSTGKP 1900

Query: 247  LQTPPPVPPQPQPPPA 262
                P  PP  QPPPA
Sbjct: 1901 TSQVPAPPPPAQPPPA 1916



 Score = 46.6 bits (109), Expect = 8e-05
 Identities = 57/247 (23%), Positives = 86/247 (34%), Gaps = 45/247 (18%)

Query: 148 LMAEALEKLFLQKINELPTEETEIMIVQAKGRGRGRKETGTAKPGV--STVPNTTQASTP 205
           +MA+A  +      N+ P+    + +    G G+   +TG ++  V  + +PN      P
Sbjct: 745 MMAQAPAQSQFLPQNQFPSSSGAMSV----GMGQPPAQTGVSQGQVPGAALPNPLNMLGP 800

Query: 206 PQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPP----- 260
             +Q P P  P  Q+  HP P           +    PP      P  P QP  P     
Sbjct: 801 QASQLPCP--PVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSG 858

Query: 261 --PAPAPQPV------QSHPPIIAA-----TPQPVKTKKGVKRKADTTTPTTIDPIH-EP 306
             P P P  V      QS P + AA     TPQP    +        ++     P+H +P
Sbjct: 859 QTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQP 918

Query: 307 PSLPPEPKTTKLGQRRESSRPV-------KPPKKDVP-----------DSQQHPAPEKSS 348
           P  P       +  R  +   V       + P  DVP           D++  P   K  
Sbjct: 919 PGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGE 978

Query: 349 KVSEQLK 355
             SE ++
Sbjct: 979 PRSEMME 985



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 27/78 (34%), Positives = 30/78 (38%), Gaps = 11/78 (14%)

Query: 237  PVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHP---PIIAATPQPVKTKKGVKRKAD 293
            P  T  PP      P  P  PQPP  P P PV   P   P +A T  P     G      
Sbjct: 1845 PSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVSTG------ 1898

Query: 294  TTTPTTIDPIHEPPSLPP 311
               PT+  P   PP+ PP
Sbjct: 1899 --KPTSQVPAPPPPAQPP 1914



 Score = 38.9 bits (89), Expect = 0.017
 Identities = 21/56 (37%), Positives = 33/56 (58%), Gaps = 3/56 (5%)

Query: 537  KKKEKDKKEKKKEKHKRKEEVEENKK---SKAKEPPPKKTKKNNSSNSNVSKKEPA 589
            K+ E++++E+KKE+     E  E  +     AK+   KKT KN SS S  +KK+P+
Sbjct: 1516 KELEQEEEERKKEESTAASETTEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPS 1571



 Score = 35.8 bits (81), Expect = 0.14
 Identities = 25/101 (24%), Positives = 36/101 (35%), Gaps = 8/101 (7%)

Query: 253  VPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPE 312
            VP Q  P P  AP    +  P    TPQP    +         +P ++ P   P     +
Sbjct: 1839 VPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQ--------PSPVSMSPAGFPSVARTQ 1890

Query: 313  PKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQ 353
            P TT    +  S  P  PP    P +    A +   +  +Q
Sbjct: 1891 PPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQ 1931



 Score = 33.1 bits (74), Expect = 0.93
 Identities = 31/106 (29%), Positives = 40/106 (37%), Gaps = 16/106 (15%)

Query: 192  GVSTVPNTTQA---------STPPQTQTP-QPNPPPVQA---TPHPFPAVTPDLIVQTPV 238
            G  + PN  QA             Q  +P QPNP   Q    +  P  +  P   + T +
Sbjct: 2242 GADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSL 2301

Query: 239  MTVV-PPQPLQTPPP--VPPQPQPPPAPAPQPVQSHPPIIAATPQP 281
               V  P P+Q+P P   PP   P P   PQP   H      +P P
Sbjct: 2302 SNQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHP 2347



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 26/130 (20%), Positives = 46/130 (35%), Gaps = 9/130 (6%)

Query: 455  AKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDS---------SSDSDSSTDDSEE 505
            A+ P  P     A     VP P+ V +  ++S               +   D+  D  E 
Sbjct: 916  AQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGES 975

Query: 506  ERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKA 565
            +   R   ++E L+   +        +Q     +  +KK + K + K +EE   N  +  
Sbjct: 976  KGEPRSEMMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQ 1035

Query: 566  KEPPPKKTKK 575
               P +  KK
Sbjct: 1036 STSPSQPRKK 1045


>gi|119943104 CREB binding protein isoform a [Homo sapiens]
          Length = 2442

 Score = 95.5 bits (236), Expect = 2e-19
 Identities = 84/304 (27%), Positives = 130/304 (42%), Gaps = 51/304 (16%)

Query: 185  ETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPP 244
            +T T  PG  +VP+ TQ  + P  Q         Q TP P   V P  +  TP  +   P
Sbjct: 897  QTPTPTPG--SVPSATQTQSTPTVQAAAQ----AQVTPQPQTPVQPPSVA-TPQSSQQQP 949

Query: 245  QPLQTPPPVPPQPQPPPA-----PAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTT 299
             P+   PP  P  Q   +     P P  V S       + QP      ++ K +T    T
Sbjct: 950  TPVHAQPPGTPLSQAAASIDNRVPTPSSVASAE---TNSQQPGPDVPVLEMKTETQAEDT 1006

Query: 300  IDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPA------PEKSSKVSEQ 353
             +P  +P     EP++  + +  + +  VK  + D+ + +  P       PE   +V E+
Sbjct: 1007 -EP--DPGESKGEPRSEMMEEDLQGASQVKE-ETDIAEQKSEPMEVDEKKPEVKVEVKEE 1062

Query: 354  LKCCSG---------------------ILKEMFAKKHAAY-----AWPFYKPVDVEALGL 387
             +  S                      + + +     A Y     + PF +PVD + LG+
Sbjct: 1063 EESSSNGTASQSTSPSQPRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGI 1122

Query: 388  HDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQ 447
             DY DI+K+PMD+STIK KL+  +Y++  ++  DV LMF+N + YN     V     KL 
Sbjct: 1123 PDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLA 1182

Query: 448  DVFE 451
            +VFE
Sbjct: 1183 EVFE 1186



 Score = 78.2 bits (191), Expect = 3e-14
 Identities = 43/159 (27%), Positives = 85/159 (53%), Gaps = 13/159 (8%)

Query: 30   QAQAQPQPANAASTNPPPPETSNPNKPKRQT---NQLQYLLRVVLKTLWKHQ-FAWPFQQ 85
            + + + +    +S+N    ++++P++P+++     +L+  L   L+ L++    + PF+Q
Sbjct: 1054 EVKVEVKEEEESSSNGTASQSTSPSQPRKKIFKPEELRQALMPTLEALYRQDPESLPFRQ 1113

Query: 86   PVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDD 145
            PVD   L +PDY+ I+K PMD+ TIK++L+   Y    + + D   MF N ++YN+    
Sbjct: 1114 PVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSR 1173

Query: 146  IVLMAEALEKLFLQKINELPTEETEIMIVQAKGRGRGRK 184
            +      L ++F Q+I+          ++Q+ G   GRK
Sbjct: 1174 VYKFCSKLAEVFEQEIDP---------VMQSLGYCCGRK 1203



 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 31/76 (40%), Positives = 35/76 (46%), Gaps = 9/76 (11%)

Query: 188  TAKPGVSTVPNTTQASTPPQTQTP-QPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQP 246
            +A PG  T     Q STP   Q P QP P PV  +P  FP+V        P  TV   +P
Sbjct: 1887 SAPPGTPT----QQPSTPQTPQPPAQPQPSPVSMSPAGFPSVART----QPPTTVSTGKP 1938

Query: 247  LQTPPPVPPQPQPPPA 262
                P  PP  QPPPA
Sbjct: 1939 TSQVPAPPPPAQPPPA 1954



 Score = 46.6 bits (109), Expect = 8e-05
 Identities = 57/247 (23%), Positives = 86/247 (34%), Gaps = 45/247 (18%)

Query: 148  LMAEALEKLFLQKINELPTEETEIMIVQAKGRGRGRKETGTAKPGV--STVPNTTQASTP 205
            +MA+A  +      N+ P+    + +    G G+   +TG ++  V  + +PN      P
Sbjct: 783  MMAQAPAQSQFLPQNQFPSSSGAMSV----GMGQPPAQTGVSQGQVPGAALPNPLNMLGP 838

Query: 206  PQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPP----- 260
              +Q P P  P  Q+  HP P           +    PP      P  P QP  P     
Sbjct: 839  QASQLPCP--PVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSG 896

Query: 261  --PAPAPQPV------QSHPPIIAA-----TPQPVKTKKGVKRKADTTTPTTIDPIH-EP 306
              P P P  V      QS P + AA     TPQP    +        ++     P+H +P
Sbjct: 897  QTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQP 956

Query: 307  PSLPPEPKTTKLGQRRESSRPV-------KPPKKDVP-----------DSQQHPAPEKSS 348
            P  P       +  R  +   V       + P  DVP           D++  P   K  
Sbjct: 957  PGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGE 1016

Query: 349  KVSEQLK 355
              SE ++
Sbjct: 1017 PRSEMME 1023



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 27/78 (34%), Positives = 30/78 (38%), Gaps = 11/78 (14%)

Query: 237  PVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHP---PIIAATPQPVKTKKGVKRKAD 293
            P  T  PP      P  P  PQPP  P P PV   P   P +A T  P     G      
Sbjct: 1883 PSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVSTG------ 1936

Query: 294  TTTPTTIDPIHEPPSLPP 311
               PT+  P   PP+ PP
Sbjct: 1937 --KPTSQVPAPPPPAQPP 1952



 Score = 38.9 bits (89), Expect = 0.017
 Identities = 21/56 (37%), Positives = 33/56 (58%), Gaps = 3/56 (5%)

Query: 537  KKKEKDKKEKKKEKHKRKEEVEENKK---SKAKEPPPKKTKKNNSSNSNVSKKEPA 589
            K+ E++++E+KKE+     E  E  +     AK+   KKT KN SS S  +KK+P+
Sbjct: 1554 KELEQEEEERKKEESTAASETTEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPS 1609



 Score = 35.8 bits (81), Expect = 0.14
 Identities = 25/101 (24%), Positives = 36/101 (35%), Gaps = 8/101 (7%)

Query: 253  VPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPE 312
            VP Q  P P  AP    +  P    TPQP    +         +P ++ P   P     +
Sbjct: 1877 VPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQ--------PSPVSMSPAGFPSVARTQ 1928

Query: 313  PKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQ 353
            P TT    +  S  P  PP    P +    A +   +  +Q
Sbjct: 1929 PPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQ 1969



 Score = 33.1 bits (74), Expect = 0.93
 Identities = 31/106 (29%), Positives = 40/106 (37%), Gaps = 16/106 (15%)

Query: 192  GVSTVPNTTQA---------STPPQTQTP-QPNPPPVQA---TPHPFPAVTPDLIVQTPV 238
            G  + PN  QA             Q  +P QPNP   Q    +  P  +  P   + T +
Sbjct: 2280 GADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSL 2339

Query: 239  MTVV-PPQPLQTPPP--VPPQPQPPPAPAPQPVQSHPPIIAATPQP 281
               V  P P+Q+P P   PP   P P   PQP   H      +P P
Sbjct: 2340 SNQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHP 2385



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 26/130 (20%), Positives = 46/130 (35%), Gaps = 9/130 (6%)

Query: 455  AKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDS---------SSDSDSSTDDSEE 505
            A+ P  P     A     VP P+ V +  ++S               +   D+  D  E 
Sbjct: 954  AQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGES 1013

Query: 506  ERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKA 565
            +   R   ++E L+   +        +Q     +  +KK + K + K +EE   N  +  
Sbjct: 1014 KGEPRSEMMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQ 1073

Query: 566  KEPPPKKTKK 575
               P +  KK
Sbjct: 1074 STSPSQPRKK 1083


>gi|40805843 K(lysine) acetyltransferase 2B [Homo sapiens]
          Length = 832

 Score = 89.0 bits (219), Expect = 1e-17
 Identities = 44/116 (37%), Positives = 64/116 (55%), Gaps = 2/116 (1%)

Query: 48  PETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDM 107
           P     +K  R  +QL   L+ +L+ +  HQ AWPF +PV   +   P YY++I+ PMD+
Sbjct: 713 PSGKEKSKEPRDPDQLYSTLKSILQQVKSHQSAWPFMEPVK--RTEAPGYYEVIRFPMDL 770

Query: 108 GTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINE 163
            T+ +RL+N YY + +  + D   +FTNC  YN P  +    A  LEK F  KI E
Sbjct: 771 KTMSERLKNRYYVSKKLFMADLQRVFTNCKEYNPPESEYYKCANILEKFFFSKIKE 826



 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 34/85 (40%), Positives = 51/85 (60%), Gaps = 5/85 (5%)

Query: 367 KKHAAYAWPFYKPVD-VEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLM 425
           K H + AWPF +PV   EA G   Y ++I+ PMD+ T+  +L+ R Y   + F AD++ +
Sbjct: 740 KSHQS-AWPFMEPVKRTEAPG---YYEVIRFPMDLKTMSERLKNRYYVSKKLFMADLQRV 795

Query: 426 FSNCYKYNPPDHEVVAMARKLQDVF 450
           F+NC +YNPP+ E    A  L+  F
Sbjct: 796 FTNCKEYNPPESEYYKCANILEKFF 820


>gi|148612882 cat eye syndrome chromosome region, candidate 2 [Homo
           sapiens]
          Length = 1484

 Score = 84.3 bits (207), Expect = 4e-16
 Identities = 90/377 (23%), Positives = 143/377 (37%), Gaps = 94/377 (24%)

Query: 47  PPETSN--PNKPKRQTNQLQYLLRV---------VLKTLWKHQFAWPFQQPVDAVKLNLP 95
           PPE S+  PN P R+  + + L  +         VL  +  H+ +WPF +PVD  +   P
Sbjct: 412 PPELSHLDPNSPMREEKKTKDLFELDDDFTAMYKVLDVVKAHKDSWPFLEPVD--ESYAP 469

Query: 96  DYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEK 155
           +YY+IIK PMD+ +++K+L    Y   +E + D  TMF NC  YN    +   M++ LE+
Sbjct: 470 NYYQIIKAPMDISSMEKKLNGGLYCTKEEFVNDMKTMFRNCRKYNGESSEYTKMSDNLER 529

Query: 156 LFLQ-KINELPTE----ETEIMIVQAKGRGRGRKETGTA--------------------- 189
            F +  +   P E    + E  I + + R + R   G +                     
Sbjct: 530 CFHRAMMKHFPGEDGDTDEEFWIREDEKREKRRSRAGRSGGSHVWTRSRDPEGSSRKQQP 589

Query: 190 -KPGVSTVPNTTQASTPPQTQTPQPNPPPVQ-------ATPHPFP-AVTPDLIVQTPVMT 240
            + G  ++P T +A +    Q+     PP +          HP     TP    Q P + 
Sbjct: 590 MENGGKSLPPTRRAPSSGDDQSSSSTQPPREVGTSNGRGFSHPLHCGGTPS---QAPFLN 646

Query: 241 VVPPQ------PLQTPPPVP-------PQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKG 287
            + P       PL+   P         P+P P      +PVQ   P     P  + + +G
Sbjct: 647 QMRPAVPGTFGPLRGSDPATLYGSSGVPEPHP-----GEPVQQRQPFTMQPPVGINSLRG 701

Query: 288 VKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQ----------------------RRESS 325
             R            +    ++ P P + +LGQ                       R   
Sbjct: 702 -PRLGTPEEKQMCGGLTHLSNMGPHPGSLQLGQISGPSQDGSMYAPAQFQPGFIPPRHGG 760

Query: 326 RPVKPPKKDVPDSQQHP 342
            P +PP  D P+S + P
Sbjct: 761 APARPP--DFPESSEIP 775



 Score = 60.1 bits (144), Expect = 7e-09
 Identities = 39/131 (29%), Positives = 59/131 (45%), Gaps = 9/131 (6%)

Query: 333 KDVPDSQQHPAPEKSSKVSEQLKCC-------SGILKEMFAKKHAAYAWPFYKPVDVEAL 385
           K++P    H  P    +  ++ K         + + K +   K    +WPF +PVD    
Sbjct: 409 KELPPELSHLDPNSPMREEKKTKDLFELDDDFTAMYKVLDVVKAHKDSWPFLEPVDESYA 468

Query: 386 GLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARK 445
              +Y  IIK PMD+S+++ KL    Y   +EF  D++ MF NC KYN    E   M+  
Sbjct: 469 P--NYYQIIKAPMDISSMEKKLNGGLYCTKEEFVNDMKTMFRNCRKYNGESSEYTKMSDN 526

Query: 446 LQDVFEMRFAK 456
           L+  F     K
Sbjct: 527 LERCFHRAMMK 537



 Score = 38.5 bits (88), Expect = 0.022
 Identities = 43/186 (23%), Positives = 65/186 (34%), Gaps = 21/186 (11%)

Query: 196  VPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTP--------DLIVQTPVMTVVPPQPL 247
            VP++     P ++   +  PPPV A    F A           D ++ +P M  +     
Sbjct: 854  VPSSGYMRPPCKSAGHRLQPPPVPAPSSLFGAPAQALRGVQGGDSMMDSPEMIAMQQLSS 913

Query: 248  QTPPPVPP----QPQPPPAPAPQPVQSHP-PIIAATPQPVKTKKGVKRKADTTTPTTIDP 302
            +  PP  P    QP  P  P P P  +HP  +  + P+P     G   +         D 
Sbjct: 914  RVCPPGVPYHPHQPAHPRLPGPFPQVAHPMSVTVSAPKPALGNPGRAPENSEAQEPENDQ 973

Query: 303  IHEPPSL---PPEPKTTKLGQRRESSRPVKPPKKDV-----PDSQQHPAPEKSSKVSEQL 354
                P L   PP   T++     +   P  P + D      P  ++   PE  S  SE  
Sbjct: 974  AEPLPGLEEKPPGVGTSEGVYLTQLPHPTPPLQTDCTRQSSPQERETVGPELKSSSSESA 1033

Query: 355  KCCSGI 360
              C  +
Sbjct: 1034 DNCKAM 1039


>gi|38788260 bromodomain PHD finger transcription factor isoform 2
            [Homo sapiens]
          Length = 2903

 Score = 82.8 bits (203), Expect = 1e-15
 Identities = 39/95 (41%), Positives = 56/95 (58%), Gaps = 2/95 (2%)

Query: 67   LRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECI 126
            L+ VL++L  H+ AWPF +PVD    + PDYY +IK PMD+ T+++R++  YY    E +
Sbjct: 2793 LKRVLRSLQAHKMAWPFLEPVDPN--DAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFV 2850

Query: 127  QDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKI 161
             D   +F NC  YN         AE LE  F+QK+
Sbjct: 2851 ADMTKIFDNCRYYNPSDSPFYQCAEVLESFFVQKL 2885



 Score = 76.6 bits (187), Expect = 7e-14
 Identities = 64/246 (26%), Positives = 96/246 (39%), Gaps = 29/246 (11%)

Query: 231  DLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKK---- 286
            DL+       V  P P  TP P P  P PPP+P P P   H  +++    P  ++K    
Sbjct: 2639 DLMQLAQATAVAAPCPPVTPAP-PAPPAPPPSPPPPPAVQHTGLLSTPTLPAASQKRKRE 2697

Query: 287  -----GVKRKADTTTPTTIDPIHEPPSL------PPEPKTTKLG----QRRESSRPVKPP 331
                   K K      TT     +   L      P +     +G    Q     R V   
Sbjct: 2698 EEKDSSSKSKKKKMISTTSKETKKDTKLYCICKTPYDESKFYIGCDRCQNWYHGRCVGIL 2757

Query: 332  KKDVPDSQQHPAPEKSSKVSEQL-------KCCSGILKEMFAKKHAAYAWPFYKPVDVEA 384
            + +     ++  P+  S             K   G+ + + + +    AWPF +PVD   
Sbjct: 2758 QSEAELIDEYVCPQCQSTEDAMTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPN- 2816

Query: 385  LGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMAR 444
                DY  +IK PMD++T++ +++ R Y    EF AD+  +F NC  YNP D      A 
Sbjct: 2817 -DAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMTKIFDNCRYYNPSDSPFYQCAE 2875

Query: 445  KLQDVF 450
             L+  F
Sbjct: 2876 VLESFF 2881



 Score = 38.9 bits (89), Expect = 0.017
 Identities = 32/157 (20%), Positives = 67/157 (42%), Gaps = 21/157 (13%)

Query: 513 ELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRK---EEVEENKKSKAKEPP 569
           E+ E ++A    +  +  P++ +  K E +   K  EK++ +   + +E++   K  +  
Sbjct: 555 EILESIRAKKGDIDNVKSPEETEKDKNETENDSKDAEKNREEFEDQSLEKDSDDKTPDDD 614

Query: 570 PKKTK---------KNNS-------SNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYE 613
           P++ K         K NS       + +N + +E +P + + P    SE  D       +
Sbjct: 615 PEQGKSEEPTEVGDKGNSVSANLGDNTTNATSEETSPSEGRSPVGCLSETPDSSNMAEKK 674

Query: 614 EKRQLSLDINKLPGE--KLGRVVHIIQSREPSLKNSN 648
              +L  D+ + P +  +         S +P+L+NSN
Sbjct: 675 VASELPQDVPEEPNKTCESSNTSATTTSIQPNLENSN 711



 Score = 34.7 bits (78), Expect = 0.32
 Identities = 59/261 (22%), Positives = 97/261 (37%), Gaps = 45/261 (17%)

Query: 484  SSSDSSSDSSSDSDSSTDDSEEERAQRLA--ELQEQLKAVHEQLAALSQPQ--------- 532
            S S+S+ ++SSD+ S  D SEE+   + +   + EQ +   + +  L   +         
Sbjct: 1409 SESNSTLENSSDTVSIQDSSEEDMIVQNSNESISEQFRTREQDVEVLEPLKCELVSGEST 1468

Query: 533  ---QNKPKKKEKDKKEKKKEKHKRKEEVEENKKS---KAKEPPPKKTKKNNSSNSNVSKK 586
               +++   K  +   KK  + K+ EE   NK S   K K    KK  +N  S       
Sbjct: 1469 GNCEDRLPVKGTEANGKKPSQQKKLEERPVNKCSDQIKLKNTTDKKNNENRESEK----- 1523

Query: 587  EPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVH---IIQSREPS 643
                 K +   T++   +D  KP  Y            L GE L  +     +  + EP 
Sbjct: 1524 -----KGQRTSTFQINGKDN-KPKIY------------LKGECLKEISESRVVSGNVEPK 1565

Query: 644  LKNSNP--DEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSS 701
            + N N    E +I   T+K S +R              +  +E    +  SS  +G    
Sbjct: 1566 VNNINKIIPENDIKSLTVKESAIRPFINGDVIMEDFNERNSSETKSHLLSSSDAEGNYRD 1625

Query: 702  ESESSSESSSSDSEDSETGPA 722
              E+   +  SDS  + T  A
Sbjct: 1626 SLETLPSTKESDSTQTTTPSA 1646



 Score = 33.9 bits (76), Expect = 0.54
 Identities = 41/167 (24%), Positives = 61/167 (36%), Gaps = 24/167 (14%)

Query: 186  TGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQ 245
            T T     +T  +TT A T  Q Q+     P +Q   H    + P    Q+  +     Q
Sbjct: 2343 TATTASTTTTTVSTTAAGTGEQRQSKLS--PQMQV--HQDKTLPP---AQSSSVGPAEAQ 2395

Query: 246  PLQTPPPVPPQPQ-PPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIH 304
            P    P   PQPQ  P +PA   VQ+ P +   T               +  P+   P H
Sbjct: 2396 PQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQT------------TVSSHVPSEAQPTH 2443

Query: 305  EPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVS 351
               S   +P+     Q + + +   P +   P SQ    P   S++S
Sbjct: 2444 AQSS---KPQVAAQSQPQSNVQGQSPVRVQSP-SQTRIRPSTPSQLS 2486


>gi|38788274 bromodomain PHD finger transcription factor isoform 1
            [Homo sapiens]
          Length = 2920

 Score = 82.8 bits (203), Expect = 1e-15
 Identities = 39/95 (41%), Positives = 56/95 (58%), Gaps = 2/95 (2%)

Query: 67   LRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECI 126
            L+ VL++L  H+ AWPF +PVD    + PDYY +IK PMD+ T+++R++  YY    E +
Sbjct: 2810 LKRVLRSLQAHKMAWPFLEPVDPN--DAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFV 2867

Query: 127  QDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKI 161
             D   +F NC  YN         AE LE  F+QK+
Sbjct: 2868 ADMTKIFDNCRYYNPSDSPFYQCAEVLESFFVQKL 2902



 Score = 76.6 bits (187), Expect = 7e-14
 Identities = 64/246 (26%), Positives = 96/246 (39%), Gaps = 29/246 (11%)

Query: 231  DLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKK---- 286
            DL+       V  P P  TP P P  P PPP+P P P   H  +++    P  ++K    
Sbjct: 2656 DLMQLAQATAVAAPCPPVTPAP-PAPPAPPPSPPPPPAVQHTGLLSTPTLPAASQKRKRE 2714

Query: 287  -----GVKRKADTTTPTTIDPIHEPPSL------PPEPKTTKLG----QRRESSRPVKPP 331
                   K K      TT     +   L      P +     +G    Q     R V   
Sbjct: 2715 EEKDSSSKSKKKKMISTTSKETKKDTKLYCICKTPYDESKFYIGCDRCQNWYHGRCVGIL 2774

Query: 332  KKDVPDSQQHPAPEKSSKVSEQL-------KCCSGILKEMFAKKHAAYAWPFYKPVDVEA 384
            + +     ++  P+  S             K   G+ + + + +    AWPF +PVD   
Sbjct: 2775 QSEAELIDEYVCPQCQSTEDAMTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPN- 2833

Query: 385  LGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMAR 444
                DY  +IK PMD++T++ +++ R Y    EF AD+  +F NC  YNP D      A 
Sbjct: 2834 -DAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMTKIFDNCRYYNPSDSPFYQCAE 2892

Query: 445  KLQDVF 450
             L+  F
Sbjct: 2893 VLESFF 2898



 Score = 34.7 bits (78), Expect = 0.32
 Identities = 59/261 (22%), Positives = 97/261 (37%), Gaps = 45/261 (17%)

Query: 484  SSSDSSSDSSSDSDSSTDDSEEERAQRLA--ELQEQLKAVHEQLAALSQPQ--------- 532
            S S+S+ ++SSD+ S  D SEE+   + +   + EQ +   + +  L   +         
Sbjct: 1283 SESNSTLENSSDTVSIQDSSEEDMIVQNSNESISEQFRTREQDVEVLEPLKCELVSGEST 1342

Query: 533  ---QNKPKKKEKDKKEKKKEKHKRKEEVEENKKS---KAKEPPPKKTKKNNSSNSNVSKK 586
               +++   K  +   KK  + K+ EE   NK S   K K    KK  +N  S       
Sbjct: 1343 GNCEDRLPVKGTEANGKKPSQQKKLEERPVNKCSDQIKLKNTTDKKNNENRESEK----- 1397

Query: 587  EPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVH---IIQSREPS 643
                 K +   T++   +D  KP  Y            L GE L  +     +  + EP 
Sbjct: 1398 -----KGQRTSTFQINGKDN-KPKIY------------LKGECLKEISESRVVSGNVEPK 1439

Query: 644  LKNSNP--DEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSS 701
            + N N    E +I   T+K S +R              +  +E    +  SS  +G    
Sbjct: 1440 VNNINKIIPENDIKSLTVKESAIRPFINGDVIMEDFNERNSSETKSHLLSSSDAEGNYRD 1499

Query: 702  ESESSSESSSSDSEDSETGPA 722
              E+   +  SDS  + T  A
Sbjct: 1500 SLETLPSTKESDSTQTTTPSA 1520



 Score = 33.9 bits (76), Expect = 0.54
 Identities = 41/167 (24%), Positives = 61/167 (36%), Gaps = 24/167 (14%)

Query: 186  TGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQ 245
            T T     +T  +TT A T  Q Q+     P +Q   H    + P    Q+  +     Q
Sbjct: 2217 TATTASTTTTTVSTTAAGTGEQRQSKLS--PQMQV--HQDKTLPP---AQSSSVGPAEAQ 2269

Query: 246  PLQTPPPVPPQPQ-PPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIH 304
            P    P   PQPQ  P +PA   VQ+ P +   T               +  P+   P H
Sbjct: 2270 PQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQT------------TVSSHVPSEAQPTH 2317

Query: 305  EPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVS 351
               S   +P+     Q + + +   P +   P SQ    P   S++S
Sbjct: 2318 AQSS---KPQVAAQSQPQSNVQGQSPVRVQSP-SQTRIRPSTPSQLS 2360



 Score = 30.0 bits (66), Expect = 7.9
 Identities = 18/86 (20%), Positives = 40/86 (46%), Gaps = 9/86 (10%)

Query: 513 ELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRK---EEVEENKKSKAKEPP 569
           E+ E ++A    +  +  P++ +  K E +   K  EK++ +   + +E++   K  +  
Sbjct: 555 EILESIRAKKGDIDNVKSPEETEKDKNETENDSKDAEKNREEFEDQSLEKDSDDKTPDDD 614

Query: 570 PKKTK------KNNSSNSNVSKKEPA 589
           P++ K      K+  SN  +S+   A
Sbjct: 615 PEQGKSEVGDFKSEKSNGELSESPGA 640


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 82.4 bits (202), Expect = 1e-15
 Identities = 134/615 (21%), Positives = 235/615 (38%), Gaps = 88/615 (14%)

Query: 138  IYNKPGDDIVLMAEALEKLFLQKINELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTV- 196
            +  K   + V++ E  E+    ++ E  TEE E    + +G+     E   A+ G     
Sbjct: 446  VVEKSEKETVIVEEQTEET---QVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETK 502

Query: 197  -PNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPP 255
             P   +A++P +    +   P  +    P  A +P+             +  ++P  V  
Sbjct: 503  SPPAEEAASPEK----EAKSPVKEEAKSPAEAKSPE------------KEEAKSPAEVK- 545

Query: 256  QPQPPPAPAPQPVQSHP------------PIIAATPQPVKT--KKGVKRKADTTTPTTI- 300
             P+   +PA +  +S P            P    +P+  K+  K+  K  A+  +P    
Sbjct: 546  SPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAK 605

Query: 301  DPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQLKCCSGI 360
             P+ E    P E K+    + +  +    P K   P  ++  +PEK +K  E+ +  S  
Sbjct: 606  SPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEK-AKSPEKEEAKSPE 664

Query: 361  LKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGA 420
              +   K  A        PV  EA         +K     S  K+K   +E   + E   
Sbjct: 665  KAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEA-KSPEKAKSPVKEEAKSPE--- 720

Query: 421  DVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPPPTKVV 480
                      K   P  E      K +   +   AK P++ + P  A +     P  K  
Sbjct: 721  ----------KAKSPVKEEAKTPEKAKSPVKEE-AKSPEKAKSPEKAKTLDVKSPEAKTP 769

Query: 481  APPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKE 540
            A   +   +      + S   +  +   +  + L+E  KA          P++  PKK+E
Sbjct: 770  AKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKA----------PEKEIPKKEE 819

Query: 541  KD---KKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPP 597
                 K+E+K ++ K KE  ++ ++ KA   P  + KK+       SKKE AP K  P P
Sbjct: 820  VKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKD-------SKKEEAPKKEAPKP 872

Query: 598  TYESEEE---DKCKPMSYEEKRQLSLDINKL--PGEKLGRVVHIIQSREPSLK----NSN 648
              E ++E   +K K    E K++ + D  K+  P ++    V + +  +P  K       
Sbjct: 873  KVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKE 932

Query: 649  PDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSK-----MKGFSSSES 703
            PD+ +   E  KP+  +E          +K K   EK    A + +      K  S  ++
Sbjct: 933  PDDAKAK-EPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKA 991

Query: 704  ESSSESSSSDSEDSE 718
            E + +SSS+D +DS+
Sbjct: 992  EKAEKSSSTDQKDSK 1006



 Score = 70.5 bits (171), Expect = 5e-12
 Identities = 109/486 (22%), Positives = 188/486 (38%), Gaps = 49/486 (10%)

Query: 184  KETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPV-QATPHPFPAVTPDLIVQTPVMTVV 242
            KE   + P   + P   +A +P + ++P+    P  +    P  A +P+   ++PV    
Sbjct: 555  KEEAKSPPEAKS-PEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEK-AKSPVKEEA 612

Query: 243  PPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDP 302
               P +   PV  + + P A    P ++  P       P K K   K +A +       P
Sbjct: 613  K-SPAEAKSPVKEEAKSP-AEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAK-SP 669

Query: 303  IHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQLKCCSGILK 362
            +      P + K+    + +   +   P K++    ++  +P K    S + K  S + +
Sbjct: 670  VKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPE-KAKSPVKE 728

Query: 363  EMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIK-HPMDMSTIKSKLEAREYR--DAQEFG 419
            E    + A        PV  EA          K   +D+ + ++K  A+E     A +F 
Sbjct: 729  EAKTPEKAK------SPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFP 782

Query: 420  ADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAV----PP 475
                       K   P  E V    K +   +   AK P++       V SP      P 
Sbjct: 783  E----------KAKSPVKEEVKSPEKAKSPLK-EDAKAPEKEIPKKEEVKSPVKEEEKPQ 831

Query: 476  PTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNK 535
              KV  PP  ++     ++       DS++E A +    + +++   E   A+ +P+++K
Sbjct: 832  EVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEP--AVEKPKESK 889

Query: 536  --PKKKEKDKKEKKKEKHKR---KEEVEENKKSKAKEPPPKK---TKKNNSSNSNVSKKE 587
               KK+E + K+K     K    K EV+E+ K K K    KK     K    +    KKE
Sbjct: 890  VEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKE 949

Query: 588  PAPMK--SKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLK 645
             AP K  +K     + EE+ K +  + E+ + LS + +K   EK  +      S     K
Sbjct: 950  AAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEK------SSSTDQK 1003

Query: 646  NSNPDE 651
            +S P E
Sbjct: 1004 DSKPPE 1009



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 52/265 (19%), Positives = 95/265 (35%), Gaps = 27/265 (10%)

Query: 460 EPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLK 519
           E EE          PP  +  +P   + S     + S +     E+E A+  AE++    
Sbjct: 490 EEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKS--- 546

Query: 520 AVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSS 579
                           P+K +   KE+ K   + K   +E  KS A+   P+K K     
Sbjct: 547 ----------------PEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKE 590

Query: 580 NSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQ----LSLDINKLPGEKLGRVVH 635
            +    +  +P K+K P   E++   + K    EE +      S +  K P ++  +   
Sbjct: 591 EAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPE 650

Query: 636 IIQSRE-PSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSK 694
             +S E    K+    +  +  E   P   +   +       K + P  E+        K
Sbjct: 651 KAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEA---KSPEK 707

Query: 695 MKGFSSSESESSSESSSSDSEDSET 719
            K     E++S  ++ S   E+++T
Sbjct: 708 AKSPVKEEAKSPEKAKSPVKEEAKT 732



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 48/229 (20%), Positives = 99/229 (43%), Gaps = 18/229 (7%)

Query: 504 EEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKK-KEKHKRKEEVEENKK 562
           + E   ++ E  E+   + E+    +Q  +   +++EK+ KE++ KE+   +EE  E  +
Sbjct: 439 KSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGE 498

Query: 563 SKAKEPP------PKKTKKN---NSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYE 613
            + K PP      P+K  K+     + S    K P   ++K P   +S E+ K  P   E
Sbjct: 499 EETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAK-SPAKEE 557

Query: 614 EKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTS 673
            K   S    K P ++  +    ++S E + K+   +E +   E   P   +   +    
Sbjct: 558 AK---SPPEAKSPEKEEAKSPAEVKSPEKA-KSPAKEEAKSPAEAKSPEKAKSPVKEEAK 613

Query: 674 CLRKKRKP---QAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSET 719
              + + P   +A+    +    K K  +  E++S  ++ S + E++++
Sbjct: 614 SPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKS 662



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 53/246 (21%), Positives = 102/246 (41%), Gaps = 23/246 (9%)

Query: 485 SSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEK--- 541
           + +   ++  +     +  EEE A+     +E+ K+   + AA  + +   P K+E    
Sbjct: 471 TEEEEKEAKEEEGKEEEGGEEEEAEGG---EEETKSPPAEEAASPEKEAKSPVKEEAKSP 527

Query: 542 -DKKEKKKEKHKRKEEVE--ENKKSKAKE----PPPKKTKKNNSSNSNVSKKEPAPMKSK 594
            + K  +KE+ K   EV+  E  KS AKE    PP  K+ +   + S    K  +P K+K
Sbjct: 528 AEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVK--SPEKAK 585

Query: 595 PPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPS-LKNSNPDEIE 653
            P   E++   + K  S E+ +    +  K P E    V    +++ P+ +K+    +  
Sbjct: 586 SPAKEEAKSPAEAK--SPEKAKSPVKEEAKSPAEAKSPVKE--EAKSPAEVKSPEKAKSP 641

Query: 654 IDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSD 713
              E   P   +  E+       K + P   +        K K    +E++S  ++ S  
Sbjct: 642 TKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEA---KSPEKAKSPVKAEAKSPEKAKSPV 698

Query: 714 SEDSET 719
            E++++
Sbjct: 699 KEEAKS 704


>gi|153791535 general control of amino acid synthesis 5-like 2 [Homo
           sapiens]
          Length = 837

 Score = 77.4 bits (189), Expect = 4e-14
 Identities = 40/116 (34%), Positives = 59/116 (50%), Gaps = 2/116 (1%)

Query: 48  PETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDM 107
           P      K  +  +QL   L+ +L  +  H  AWPF +PV   K   PDYY++I+ P+D+
Sbjct: 718 PLGKEKGKELKDPDQLYTTLKNLLAQIKSHPSAWPFMEPVK--KSEAPDYYEVIRFPIDL 775

Query: 108 GTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINE 163
            T+ +RL + YY   +  + D   +  NC  YN P  +    A ALEK F  K+ E
Sbjct: 776 KTMTERLRSRYYVTRKLFVADLQRVIANCREYNPPDSEYCRCASALEKFFYFKLKE 831



 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 33/91 (36%), Positives = 51/91 (56%), Gaps = 3/91 (3%)

Query: 361 LKEMFAK-KHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFG 419
           LK + A+ K    AWPF +PV        DY ++I+ P+D+ T+  +L +R Y   + F 
Sbjct: 737 LKNLLAQIKSHPSAWPFMEPVKKSEAP--DYYEVIRFPIDLKTMTERLRSRYYVTRKLFV 794

Query: 420 ADVRLMFSNCYKYNPPDHEVVAMARKLQDVF 450
           AD++ + +NC +YNPPD E    A  L+  F
Sbjct: 795 ADLQRVIANCREYNPPDSEYCRCASALEKFF 825



 Score = 38.1 bits (87), Expect = 0.029
 Identities = 18/39 (46%), Positives = 21/39 (53%), Gaps = 3/39 (7%)

Query: 244 PQPLQTPPPVP---PQPQPPPAPAPQPVQSHPPIIAATP 279
           P+PLQ+P P P   P P P  AP P P  +  P  AA P
Sbjct: 16  PRPLQSPAPAPTPTPAPSPASAPIPTPTPAPAPAPAAAP 54



 Score = 37.4 bits (85), Expect = 0.049
 Identities = 28/68 (41%), Positives = 30/68 (44%), Gaps = 16/68 (23%)

Query: 205 PPQTQTPQP--NPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPA 262
           P Q  TP P   P P+Q+   P PA TP     TP      P P   P P P  P P PA
Sbjct: 4   PSQAPTPAPAAQPRPLQS---PAPAPTP-----TPA-----PSPASAPIPTPT-PAPAPA 49

Query: 263 PAPQPVQS 270
           PA  P  S
Sbjct: 50  PAAAPAGS 57



 Score = 35.4 bits (80), Expect = 0.19
 Identities = 17/40 (42%), Positives = 20/40 (50%), Gaps = 3/40 (7%)

Query: 245 QPLQTPPPVP---PQPQPPPAPAPQPVQSHPPIIAATPQP 281
           +P Q P P P   P+P   PAPAP P  +  P  A  P P
Sbjct: 3   EPSQAPTPAPAAQPRPLQSPAPAPTPTPAPSPASAPIPTP 42



 Score = 34.3 bits (77), Expect = 0.42
 Identities = 24/58 (41%), Positives = 27/58 (46%), Gaps = 8/58 (13%)

Query: 217 PVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQ-PQPPPAPAPQPVQSHPP 273
           P QA P P PA  P  + Q+P      P P  TP P P   P P P PAP P  +  P
Sbjct: 4   PSQA-PTPAPAAQPRPL-QSPA-----PAPTPTPAPSPASAPIPTPTPAPAPAPAAAP 54


>gi|47419911 transcriptional intermediary factor 1 alpha isoform a
            [Homo sapiens]
          Length = 1050

 Score = 74.7 bits (182), Expect = 3e-13
 Identities = 44/124 (35%), Positives = 66/124 (53%), Gaps = 12/124 (9%)

Query: 54   NKPKRQTNQLQYLLRV-------VLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMD 106
            N  K++T  L  L  +       +L  L+ H+ +  FQ PV    L +PDYYKIIK PMD
Sbjct: 888  NSEKKKTEGLVKLTPIDKRKCERLLLFLYCHEMSLAFQDPVP---LTVPDYYKIIKNPMD 944

Query: 107  MGTIKKRLENNY--YWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINEL 164
            + TIKKRL+ +Y  Y   ++ + DF  +F NC  +N+P  ++      LE  F + +  L
Sbjct: 945  LSTIKKRLQEDYSMYSKPEDFVADFRLIFQNCAEFNEPDSEVANAGIKLENYFEELLKNL 1004

Query: 165  PTEE 168
              E+
Sbjct: 1005 YPEK 1008



 Score = 69.7 bits (169), Expect = 9e-12
 Identities = 47/139 (33%), Positives = 67/139 (48%), Gaps = 20/139 (14%)

Query: 381  DVEALGLHDYCDIIKHPMDMSTIKSKLEA--REYRDAQEFGADVRLMFSNCYKYNPPDHE 438
            D   L + DY  IIK+PMD+STIK +L+     Y   ++F AD RL+F NC ++N PD E
Sbjct: 926  DPVPLTVPDYYKIIKNPMDLSTIKKRLQEDYSMYSKPEDFVADFRLIFQNCAEFNEPDSE 985

Query: 439  VVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDS 498
            V     KL++ FE     +  E   P                  P   + S D+   SD 
Sbjct: 986  VANAGIKLENYFEELLKNLYPEKRFP-----------------KPEFRNESEDNKF-SDD 1027

Query: 499  STDDSEEERAQRLAELQEQ 517
            S DD  + R +RL  ++E+
Sbjct: 1028 SDDDFVQPRKKRLKSIEER 1046


>gi|47419909 transcriptional intermediary factor 1 alpha isoform b
           [Homo sapiens]
          Length = 1016

 Score = 74.7 bits (182), Expect = 3e-13
 Identities = 44/124 (35%), Positives = 66/124 (53%), Gaps = 12/124 (9%)

Query: 54  NKPKRQTNQLQYLLRV-------VLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMD 106
           N  K++T  L  L  +       +L  L+ H+ +  FQ PV    L +PDYYKIIK PMD
Sbjct: 854 NSEKKKTEGLVKLTPIDKRKCERLLLFLYCHEMSLAFQDPVP---LTVPDYYKIIKNPMD 910

Query: 107 MGTIKKRLENNY--YWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINEL 164
           + TIKKRL+ +Y  Y   ++ + DF  +F NC  +N+P  ++      LE  F + +  L
Sbjct: 911 LSTIKKRLQEDYSMYSKPEDFVADFRLIFQNCAEFNEPDSEVANAGIKLENYFEELLKNL 970

Query: 165 PTEE 168
             E+
Sbjct: 971 YPEK 974



 Score = 69.7 bits (169), Expect = 9e-12
 Identities = 47/139 (33%), Positives = 67/139 (48%), Gaps = 20/139 (14%)

Query: 381  DVEALGLHDYCDIIKHPMDMSTIKSKLEA--REYRDAQEFGADVRLMFSNCYKYNPPDHE 438
            D   L + DY  IIK+PMD+STIK +L+     Y   ++F AD RL+F NC ++N PD E
Sbjct: 892  DPVPLTVPDYYKIIKNPMDLSTIKKRLQEDYSMYSKPEDFVADFRLIFQNCAEFNEPDSE 951

Query: 439  VVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDS 498
            V     KL++ FE     +  E   P                  P   + S D+   SD 
Sbjct: 952  VANAGIKLENYFEELLKNLYPEKRFP-----------------KPEFRNESEDNKF-SDD 993

Query: 499  STDDSEEERAQRLAELQEQ 517
            S DD  + R +RL  ++E+
Sbjct: 994  SDDDFVQPRKKRLKSIEER 1012


>gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo
            sapiens]
          Length = 2168

 Score = 73.2 bits (178), Expect = 8e-13
 Identities = 45/134 (33%), Positives = 68/134 (50%), Gaps = 20/134 (14%)

Query: 321  RRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQLKCCSGILKEMFAKKHAAYAWPFYKPV 380
            ++ES   VK PK+D                S+ L  CS IL EM   + A   WPF  PV
Sbjct: 2048 KQESFTSVKKPKRDD---------------SKDLALCSMILTEMETHEDA---WPFLLPV 2089

Query: 381  DVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVV 440
            +++ +    Y  +IK PMD STI+ KL + +Y + + F  DVRL+F NC  +N  D ++ 
Sbjct: 2090 NLKLVP--GYKKVIKKPMDFSTIREKLSSGQYPNLETFALDVRLVFDNCETFNEDDSDIG 2147

Query: 441  AMARKLQDVFEMRF 454
                 ++  FE ++
Sbjct: 2148 RAGHNMRKYFEKKW 2161



 Score = 68.2 bits (165), Expect = 3e-11
 Identities = 38/106 (35%), Positives = 58/106 (54%), Gaps = 2/106 (1%)

Query: 55   KPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRL 114
            KPKR  ++   L  ++L  +  H+ AWPF  PV+ +KL +P Y K+IK PMD  TI+++L
Sbjct: 2057 KPKRDDSKDLALCSMILTEMETHEDAWPFLLPVN-LKL-VPGYKKVIKKPMDFSTIREKL 2114

Query: 115  ENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQK 160
             +  Y N +    D   +F NC  +N+   DI      + K F +K
Sbjct: 2115 SSGQYPNLETFALDVRLVFDNCETFNEDDSDIGRAGHNMRKYFEKK 2160



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 56/256 (21%), Positives = 104/256 (40%), Gaps = 38/256 (14%)

Query: 481 APPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKE 540
           A  SSS+S SDS + SD+S++      +  L E +E             +  Q+  + ++
Sbjct: 238 AMESSSNSDSDSGTSSDTSSEGISSSDSDDLEEDEE-------------EEDQSIEESED 284

Query: 541 KDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYE 600
            D   + + +HK   +V  +  S  K    K T+K      +    +P P+ S+   T+ 
Sbjct: 285 DDSDSESEAQHKSNNQVLLHGISDPKADGQKATEKAQEKRIH----QPLPLASE-SQTHS 339

Query: 601 SEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQS-------REPSLKNSNPDEIE 653
            + + K +P    ++       ++   E + +   +IQS       +  SL N    E  
Sbjct: 340 FQSQQK-QPQVLSQQLPFIFQSSQAKEESVNKHTSVIQSTGLVSNVKPLSLVNQAKKETY 398

Query: 654 IDFETLKPSTLR-------ELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESS 706
           +      P  L+       E    +TS LR KR+   +     A  S++K   SS+S   
Sbjct: 399 MKLIVPSPDVLKAGNKNTSEESSLLTSELRSKREQYKQ-----AFPSQLKKQESSKSLKK 453

Query: 707 SESSSSDSEDSETGPA 722
             ++ S+ + + + PA
Sbjct: 454 VIAALSNPKATSSSPA 469



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 27/117 (23%), Positives = 49/117 (41%), Gaps = 6/117 (5%)

Query: 475 PPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQN 534
           P   +V     +DS   SS DS+ S +D EE+  +   E  E  ++   Q  + S  + +
Sbjct: 583 PAKSLVEQFRGTDSDIPSSKDSEDSNEDEEEDDEEEDEEDDEDDESDDSQSESDSNSESD 642

Query: 535 KPKKKEKDKKEKKKEKHKRKEEVEENK------KSKAKEPPPKKTKKNNSSNSNVSK 585
               +E+D  +K +++     E E+         S  K P    T  +   N +++K
Sbjct: 643 TEGSEEEDDDDKDQDESDSDTEGEKTSMKLNKTTSSVKSPSMSLTGHSTPRNLHIAK 699



 Score = 34.7 bits (78), Expect = 0.32
 Identities = 30/118 (25%), Positives = 61/118 (51%), Gaps = 14/118 (11%)

Query: 482 PPSSSDSSSDSSSDSDSSTDDSEEERAQRLAEL--------QEQLKAVHE---QLAALSQ 530
           PP+  ++    ++D+        +E A++ A++        QEQ +   E   Q A ++ 
Sbjct: 869 PPNVGNAEFLDNADAKLLRKLQAQEIARQAAQIKLLRKLQKQEQARVAKEAKKQQAIMAA 928

Query: 531 PQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKE-PPPKKTKKNNSSNSNVSKKE 587
             + K K+KE+ K  K++EK KR +++   K+ +A++    KK KK  ++N+ + + E
Sbjct: 929 --EEKRKQKEQIKIMKQQEKIKRIQQIRMEKELRAQQILEAKKKKKEEAANAKLLEAE 984



 Score = 33.1 bits (74), Expect = 0.93
 Identities = 51/247 (20%), Positives = 95/247 (38%), Gaps = 13/247 (5%)

Query: 473 VPPPTKVVAPPSSS-DSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALS-- 529
           +PP   + APP+ + DSSS  S  S  S  +  E+              +    + LS  
Sbjct: 136 IPP---LFAPPAQNHDSSSFHSRTSGKSNRNGPEKGVNGSINGSNTSSVIGINTSVLSTT 192

Query: 530 -QPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEP 588
                 + K        +K  + + K +  + +  K K+  P+K    +SSNS+      
Sbjct: 193 ASSSMGQTKSTSSGGGNRKCNQEQSKNQPLDARVDKIKDKKPRKKAMESSSNSDSDSGTS 252

Query: 589 APMKSKPPPTYES---EEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLK 645
           +   S+   + +S   EE+++ +  S EE      D       K    V +    +P   
Sbjct: 253 SDTSSEGISSSDSDDLEEDEEEEDQSIEESEDDDSDSESEAQHKSNNQVLLHGISDPKAD 312

Query: 646 NSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQ--AEKVDVIAGSSKMKGFSSSES 703
                E   +    +P  L   E    S   ++++PQ  ++++  I  SS+ K  S ++ 
Sbjct: 313 GQKATEKAQEKRIHQPLPLAS-ESQTHSFQSQQKQPQVLSQQLPFIFQSSQAKEESVNKH 371

Query: 704 ESSSESS 710
            S  +S+
Sbjct: 372 TSVIQST 378



 Score = 30.4 bits (67), Expect = 6.0
 Identities = 28/118 (23%), Positives = 57/118 (48%), Gaps = 10/118 (8%)

Query: 503  SEEERAQRLAELQEQLKAVHEQ--LAALSQPQQNKPKKKEK--DKKEKKKEKHKRKEEVE 558
            +EE+R Q+     EQ+K + +Q  +  + Q +  K  + ++  + K+KKKE+    + +E
Sbjct: 928  AEEKRKQK-----EQIKIMKQQEKIKRIQQIRMEKELRAQQILEAKKKKKEEAANAKLLE 982

Query: 559  ENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKR 616
              K+ K KE   ++            ++    MK+      ++EE+++ K    +EKR
Sbjct: 983  AEKRIKEKEMRRQQAVLLKHQERERRRQHMMLMKAM-EARKKAEEKERLKQEKRDEKR 1039



 Score = 30.0 bits (66), Expect = 7.9
 Identities = 25/95 (26%), Positives = 47/95 (49%), Gaps = 5/95 (5%)

Query: 504  EEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKD--KKEKKKEKHKRKEEVEENK 561
            +E R Q+   L+ Q +    Q   L +  + + K +EK+  K+EK+ EK   KE   E +
Sbjct: 990  KEMRRQQAVLLKHQERERRRQHMMLMKAMEARKKAEEKERLKQEKRDEKRLNKERKLEQR 1049

Query: 562  KSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPP 596
            + + +    K+ KK N  +  ++ ++P P   + P
Sbjct: 1050 RLELE--MAKELKKPN-EDMCLADQKPLPELPRIP 1081


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 72.8 bits (177), Expect = 1e-12
 Identities = 53/170 (31%), Positives = 63/170 (37%), Gaps = 27/170 (15%)

Query: 186  TGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQ 245
            T T  P  +  P TT  +TPP T TP    PP+  T  P P  TP      P+ T   P 
Sbjct: 1413 TTTLPPTTTPSPPTTTTTTPPPTTTPS---PPITTTTTPPPTTTP----SPPISTTTTPP 1465

Query: 246  PLQTPPPVPPQPQPP-PAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDP-- 302
            P  TP P    P PP   P+P    +  P    TP P  T       + TT P T  P  
Sbjct: 1466 PTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSP 1525

Query: 303  -----IHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDV---PDSQQHPAP 344
                    PP+  P P TT          P+ PP       P +   P P
Sbjct: 1526 PTTTTTTPPPTTTPSPPTT---------TPITPPTSTTTLPPTTTPSPPP 1566



 Score = 68.6 bits (166), Expect = 2e-11
 Identities = 44/132 (33%), Positives = 51/132 (38%), Gaps = 8/132 (6%)

Query: 186  TGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQ 245
            T  + P  +  P  T  +T P T TP    PP   T  P P  TP      P+ T   P 
Sbjct: 1397 TTPSPPTTTPSPPPTSTTTLPPTTTPS---PPTTTTTTPPPTTTP----SPPITTTTTPP 1449

Query: 246  PLQTP-PPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIH 304
            P  TP PP+     PPP   P P  + P     TP P  T         T +P T  PI 
Sbjct: 1450 PTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPIT 1509

Query: 305  EPPSLPPEPKTT 316
             P S    P TT
Sbjct: 1510 PPASTTTLPPTT 1521



 Score = 67.4 bits (163), Expect = 4e-11
 Identities = 47/160 (29%), Positives = 58/160 (36%), Gaps = 7/160 (4%)

Query: 186  TGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQ 245
            T T  P  +  P TT  +TPP T TP P P     TP       P     +P     PP 
Sbjct: 1514 TTTLPPTTTPSPPTTTTTTPPPTTTPSP-PTTTPITPPTSTTTLPPTTTPSP-----PPT 1567

Query: 246  PLQTPPPVP-PQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIH 304
               TPPP   P P     P+P  + +  P    TP P  T         T +P T  PI 
Sbjct: 1568 TTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPIT 1627

Query: 305  EPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAP 344
             P S    P TT       ++    P     P +   P+P
Sbjct: 1628 PPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSP 1667



 Score = 64.3 bits (155), Expect = 4e-10
 Identities = 52/178 (29%), Positives = 65/178 (36%), Gaps = 14/178 (7%)

Query: 186  TGTAKPGVSTVPNTTQASTPPQTQTPQPNP----PPVQATPHPFPAVTPDLIVQTPVM-- 239
            T T  P  +  P TT   TPP + T  P      PP   T  P P  TP     TP+   
Sbjct: 1491 TTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPP 1550

Query: 240  ---TVVPPQPLQTPPPVPPQPQPP-PAPAPQPVQS-HPPIIAATPQPVKTKKGVKRKADT 294
               T +PP    +PPP      PP   P+P    +  PP I  T  P  T         T
Sbjct: 1551 TSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTT 1610

Query: 295  TTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPP-KKDVPDSQQHPAPEKSSKVS 351
            T P T  P   PP+  P    T       ++ P  PP     P     P+P  ++  S
Sbjct: 1611 TPPPTTTP--SPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPS 1666



 Score = 63.9 bits (154), Expect = 5e-10
 Identities = 43/138 (31%), Positives = 53/138 (38%), Gaps = 14/138 (10%)

Query: 186  TGTAKPGVSTVPNTTQASTPPQTQTPQP-----NPPPVQATPHPFPAVTPDLIVQT---- 236
            T T  P  +  P  T  +TPP T TP P       PP+  T  P P  TP   + T    
Sbjct: 1632 TTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSP 1691

Query: 237  PVMTVVPPQPLQTPP---PVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKAD 293
            P  T+  P P  TP         P     P+P P     P    TP P  T         
Sbjct: 1692 PTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTT 1751

Query: 294  TTTPTTIDPIHEPPSLPP 311
            T++P T  P+  PPS+ P
Sbjct: 1752 TSSPLTTTPL--PPSITP 1767



 Score = 63.2 bits (152), Expect = 8e-10
 Identities = 46/153 (30%), Positives = 54/153 (35%), Gaps = 14/153 (9%)

Query: 186  TGTAKPGVSTVPNTTQASTPPQTQTPQP------NPPPVQATPHPFPAVTPDLIVQTPVM 239
            T  + P  +  P TT  +TPP T TP P       PP    T  P    +P     T   
Sbjct: 1475 TTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPP 1534

Query: 240  TVVPPQPLQTPPPVPPQPQP--PPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTP 297
                P P  T P  PP      PP   P P    PP    TP P  T         T +P
Sbjct: 1535 PTTTPSPPTTTPITPPTSTTTLPPTTTPSP----PPTTTTTPPPTTTPS--PPTTTTPSP 1588

Query: 298  TTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKP 330
             TI     PP+  P P TT       ++ P  P
Sbjct: 1589 PTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPP 1621



 Score = 63.2 bits (152), Expect = 8e-10
 Identities = 48/159 (30%), Positives = 55/159 (34%), Gaps = 12/159 (7%)

Query: 186  TGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQ 245
            T T  P  +  P TT  +TPP T TP P P     TP   P  T  L    P  T  PP 
Sbjct: 1593 TTTPPPTTTPSPPTTTTTTPPPTTTPSP-PTTTPITP---PTSTTTL---PPTTTPSPPP 1645

Query: 246  PLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHE 305
               T PP    P PP    P      PPI   T  P  T          + PTT      
Sbjct: 1646 TTTTTPPPTTTPSPPTTTTPS-----PPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPS 1700

Query: 306  PPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAP 344
            P + P  P TT       ++    P     P     P+P
Sbjct: 1701 PTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSP 1739



 Score = 60.8 bits (146), Expect = 4e-09
 Identities = 55/181 (30%), Positives = 71/181 (39%), Gaps = 28/181 (15%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP--PPVQATPHPFPAVTPDLIVQTPVMT 240
            TGT  P  + +  TT  +   TP  TQTP   P       TP P P  T     QTP  T
Sbjct: 4122 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTT 4176

Query: 241  VVPPQPLQTPPPVPPQPQPPP------APAPQPVQSHPPIIAATPQPVKTKKGVKRKADT 294
             +      TP P P   Q  P      AP  +   S+PP  ++TPQ  ++      ++ T
Sbjct: 4177 PITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTES-T 4235

Query: 295  TTPTTIDPIHE-----PPSLPPEPKTTKLGQ------RRESSRPVKPPKKDVPDSQQHPA 343
            T  +T+ P  E     PPS P  P TT  G          +S P  P +     S   P 
Sbjct: 4236 TLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPT 4295

Query: 344  P 344
            P
Sbjct: 4296 P 4296



 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 50/165 (30%), Positives = 59/165 (35%), Gaps = 17/165 (10%)

Query: 186  TGTAKPGVSTV----PNTTQASTPPQTQTPQP--NPPPVQATPHPFPAVTPDLIVQTPVM 239
            T T  P ++T     P TT +     T TP P   P P   TP P P  TP      P  
Sbjct: 1435 TTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSP-PTTTP----SPPTT 1489

Query: 240  TVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTT 299
            T   P P  TP P    P  PPA       + PP    TP P  T         T +P T
Sbjct: 1490 TTTTPPPTTTPSPPTTTPITPPA----STTTLPP--TTTPSPPTTTTTTPPPTTTPSPPT 1543

Query: 300  IDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAP 344
              PI  P S    P TT       ++    P     P +   P+P
Sbjct: 1544 TTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSP 1588



 Score = 56.6 bits (135), Expect = 8e-08
 Identities = 42/144 (29%), Positives = 52/144 (36%), Gaps = 14/144 (9%)

Query: 186  TGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIV--QTPVMTVVP 243
            T  + P  + +   T  +T P T TP P PP    TP P    +P        P+ T   
Sbjct: 1616 TTPSPPTTTPITPPTSTTTLPPTTTPSP-PPTTTTTPPPTTTPSPPTTTTPSPPITTTTT 1674

Query: 244  PQPLQTP-PPVPPQPQPP----PAPAPQPVQSHP------PIIAATPQPVKTKKGVKRKA 292
            P P  TP  P+   P PP      P+P    S P      P    TP P  T        
Sbjct: 1675 PPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPT 1734

Query: 293  DTTTPTTIDPIHEPPSLPPEPKTT 316
             T +P T      PP+    P TT
Sbjct: 1735 TTPSPPTTTMTTLPPTTTSSPLTT 1758



 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 53/192 (27%), Positives = 64/192 (33%), Gaps = 31/192 (16%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP--PPVQATPHPFPAVTPDLIVQTPVMT 240
            TGT  P  + +  TT  +   TP  TQTP   P       TP P P  T     QTP  T
Sbjct: 4053 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTT 4107

Query: 241  VVPPQPLQTPPPVPPQPQPPP----------APAPQPVQSHPP-------IIAATPQPVK 283
             +      TP P P   Q P            P P P  +  P           TP P  
Sbjct: 4108 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 4167

Query: 284  TKKGVKRKADTTTPTTIDPIHEPPSLPPEPKT-TKLGQRRESSRPVKPPKKDVPD---SQ 339
            T          TT TT+ P   P      P T T      E +    PP+   P    S 
Sbjct: 4168 TGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRST 4227

Query: 340  QHPAPEKSSKVS 351
              P  E ++ +S
Sbjct: 4228 SSPLTESTTLLS 4239



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 46/153 (30%), Positives = 52/153 (33%), Gaps = 22/153 (14%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP----PPVQATPHPFPAVTPDLIVQTPV 238
            TGT  P  + +  TT  +   TP  TQTP   P      V  TP P    TP     T  
Sbjct: 1960 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2019

Query: 239  MTVVP---PQPLQTPPPVPPQPQPPPAPAPQPVQSHPP-------IIAATPQPVKTKKGV 288
             TV P   P   QTP   P        P P P  +  P           TP P  T    
Sbjct: 2020 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2079

Query: 289  KRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
                  TT TT+ P   P     P+  P   TT
Sbjct: 2080 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2112



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 46/153 (30%), Positives = 52/153 (33%), Gaps = 22/153 (14%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP----PPVQATPHPFPAVTPDLIVQTPV 238
            TGT  P  + +  TT  +   TP  TQTP   P      V  TP P    TP     T  
Sbjct: 2029 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2088

Query: 239  MTVVP---PQPLQTPPPVPPQPQPPPAPAPQPVQSHPP-------IIAATPQPVKTKKGV 288
             TV P   P   QTP   P        P P P  +  P           TP P  T    
Sbjct: 2089 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2148

Query: 289  KRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
                  TT TT+ P   P     P+  P   TT
Sbjct: 2149 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2181



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 46/153 (30%), Positives = 52/153 (33%), Gaps = 22/153 (14%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP----PPVQATPHPFPAVTPDLIVQTPV 238
            TGT  P  + +  TT  +   TP  TQTP   P      V  TP P    TP     T  
Sbjct: 2098 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2157

Query: 239  MTVVP---PQPLQTPPPVPPQPQPPPAPAPQPVQSHPP-------IIAATPQPVKTKKGV 288
             TV P   P   QTP   P        P P P  +  P           TP P  T    
Sbjct: 2158 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2217

Query: 289  KRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
                  TT TT+ P   P     P+  P   TT
Sbjct: 2218 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2250



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 46/153 (30%), Positives = 52/153 (33%), Gaps = 22/153 (14%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP----PPVQATPHPFPAVTPDLIVQTPV 238
            TGT  P  + +  TT  +   TP  TQTP   P      V  TP P    TP     T  
Sbjct: 2167 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2226

Query: 239  MTVVP---PQPLQTPPPVPPQPQPPPAPAPQPVQSHPP-------IIAATPQPVKTKKGV 288
             TV P   P   QTP   P        P P P  +  P           TP P  T    
Sbjct: 2227 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2286

Query: 289  KRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
                  TT TT+ P   P     P+  P   TT
Sbjct: 2287 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2319



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 46/153 (30%), Positives = 52/153 (33%), Gaps = 22/153 (14%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP----PPVQATPHPFPAVTPDLIVQTPV 238
            TGT  P  + +  TT  +   TP  TQTP   P      V  TP P    TP     T  
Sbjct: 2236 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2295

Query: 239  MTVVP---PQPLQTPPPVPPQPQPPPAPAPQPVQSHPP-------IIAATPQPVKTKKGV 288
             TV P   P   QTP   P        P P P  +  P           TP P  T    
Sbjct: 2296 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2355

Query: 289  KRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
                  TT TT+ P   P     P+  P   TT
Sbjct: 2356 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2388



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 46/153 (30%), Positives = 52/153 (33%), Gaps = 22/153 (14%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP----PPVQATPHPFPAVTPDLIVQTPV 238
            TGT  P  + +  TT  +   TP  TQTP   P      V  TP P    TP     T  
Sbjct: 2305 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2364

Query: 239  MTVVP---PQPLQTPPPVPPQPQPPPAPAPQPVQSHPP-------IIAATPQPVKTKKGV 288
             TV P   P   QTP   P        P P P  +  P           TP P  T    
Sbjct: 2365 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2424

Query: 289  KRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
                  TT TT+ P   P     P+  P   TT
Sbjct: 2425 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2457



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 46/153 (30%), Positives = 52/153 (33%), Gaps = 22/153 (14%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP----PPVQATPHPFPAVTPDLIVQTPV 238
            TGT  P  + +  TT  +   TP  TQTP   P      V  TP P    TP     T  
Sbjct: 2374 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2433

Query: 239  MTVVP---PQPLQTPPPVPPQPQPPPAPAPQPVQSHPP-------IIAATPQPVKTKKGV 288
             TV P   P   QTP   P        P P P  +  P           TP P  T    
Sbjct: 2434 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2493

Query: 289  KRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
                  TT TT+ P   P     P+  P   TT
Sbjct: 2494 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2526



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 46/153 (30%), Positives = 52/153 (33%), Gaps = 22/153 (14%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP----PPVQATPHPFPAVTPDLIVQTPV 238
            TGT  P  + +  TT  +   TP  TQTP   P      V  TP P    TP     T  
Sbjct: 2443 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2502

Query: 239  MTVVP---PQPLQTPPPVPPQPQPPPAPAPQPVQSHPP-------IIAATPQPVKTKKGV 288
             TV P   P   QTP   P        P P P  +  P           TP P  T    
Sbjct: 2503 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2562

Query: 289  KRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
                  TT TT+ P   P     P+  P   TT
Sbjct: 2563 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2595



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 46/153 (30%), Positives = 52/153 (33%), Gaps = 22/153 (14%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP----PPVQATPHPFPAVTPDLIVQTPV 238
            TGT  P  + +  TT  +   TP  TQTP   P      V  TP P    TP     T  
Sbjct: 2512 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2571

Query: 239  MTVVP---PQPLQTPPPVPPQPQPPPAPAPQPVQSHPP-------IIAATPQPVKTKKGV 288
             TV P   P   QTP   P        P P P  +  P           TP P  T    
Sbjct: 2572 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2631

Query: 289  KRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
                  TT TT+ P   P     P+  P   TT
Sbjct: 2632 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2664



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 46/153 (30%), Positives = 52/153 (33%), Gaps = 22/153 (14%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP----PPVQATPHPFPAVTPDLIVQTPV 238
            TGT  P  + +  TT  +   TP  TQTP   P      V  TP P    TP     T  
Sbjct: 2581 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2640

Query: 239  MTVVP---PQPLQTPPPVPPQPQPPPAPAPQPVQSHPP-------IIAATPQPVKTKKGV 288
             TV P   P   QTP   P        P P P  +  P           TP P  T    
Sbjct: 2641 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2700

Query: 289  KRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
                  TT TT+ P   P     P+  P   TT
Sbjct: 2701 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2733



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 46/153 (30%), Positives = 52/153 (33%), Gaps = 22/153 (14%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP----PPVQATPHPFPAVTPDLIVQTPV 238
            TGT  P  + +  TT  +   TP  TQTP   P      V  TP P    TP     T  
Sbjct: 2650 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2709

Query: 239  MTVVP---PQPLQTPPPVPPQPQPPPAPAPQPVQSHPP-------IIAATPQPVKTKKGV 288
             TV P   P   QTP   P        P P P  +  P           TP P  T    
Sbjct: 2710 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2769

Query: 289  KRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
                  TT TT+ P   P     P+  P   TT
Sbjct: 2770 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2802



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 46/153 (30%), Positives = 52/153 (33%), Gaps = 22/153 (14%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP----PPVQATPHPFPAVTPDLIVQTPV 238
            TGT  P  + +  TT  +   TP  TQTP   P      V  TP P    TP     T  
Sbjct: 2719 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2778

Query: 239  MTVVP---PQPLQTPPPVPPQPQPPPAPAPQPVQSHPP-------IIAATPQPVKTKKGV 288
             TV P   P   QTP   P        P P P  +  P           TP P  T    
Sbjct: 2779 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2838

Query: 289  KRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
                  TT TT+ P   P     P+  P   TT
Sbjct: 2839 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2871



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 46/153 (30%), Positives = 52/153 (33%), Gaps = 22/153 (14%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP----PPVQATPHPFPAVTPDLIVQTPV 238
            TGT  P  + +  TT  +   TP  TQTP   P      V  TP P    TP     T  
Sbjct: 2788 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2847

Query: 239  MTVVP---PQPLQTPPPVPPQPQPPPAPAPQPVQSHPP-------IIAATPQPVKTKKGV 288
             TV P   P   QTP   P        P P P  +  P           TP P  T    
Sbjct: 2848 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2907

Query: 289  KRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
                  TT TT+ P   P     P+  P   TT
Sbjct: 2908 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2940



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 46/153 (30%), Positives = 52/153 (33%), Gaps = 22/153 (14%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP----PPVQATPHPFPAVTPDLIVQTPV 238
            TGT  P  + +  TT  +   TP  TQTP   P      V  TP P    TP     T  
Sbjct: 2857 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2916

Query: 239  MTVVP---PQPLQTPPPVPPQPQPPPAPAPQPVQSHPP-------IIAATPQPVKTKKGV 288
             TV P   P   QTP   P        P P P  +  P           TP P  T    
Sbjct: 2917 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2976

Query: 289  KRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
                  TT TT+ P   P     P+  P   TT
Sbjct: 2977 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3009



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 46/153 (30%), Positives = 52/153 (33%), Gaps = 22/153 (14%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP----PPVQATPHPFPAVTPDLIVQTPV 238
            TGT  P  + +  TT  +   TP  TQTP   P      V  TP P    TP     T  
Sbjct: 2926 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2985

Query: 239  MTVVP---PQPLQTPPPVPPQPQPPPAPAPQPVQSHPP-------IIAATPQPVKTKKGV 288
             TV P   P   QTP   P        P P P  +  P           TP P  T    
Sbjct: 2986 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3045

Query: 289  KRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
                  TT TT+ P   P     P+  P   TT
Sbjct: 3046 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3078



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 46/153 (30%), Positives = 52/153 (33%), Gaps = 22/153 (14%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP----PPVQATPHPFPAVTPDLIVQTPV 238
            TGT  P  + +  TT  +   TP  TQTP   P      V  TP P    TP     T  
Sbjct: 2995 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3054

Query: 239  MTVVP---PQPLQTPPPVPPQPQPPPAPAPQPVQSHPP-------IIAATPQPVKTKKGV 288
             TV P   P   QTP   P        P P P  +  P           TP P  T    
Sbjct: 3055 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3114

Query: 289  KRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
                  TT TT+ P   P     P+  P   TT
Sbjct: 3115 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3147



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 46/153 (30%), Positives = 52/153 (33%), Gaps = 22/153 (14%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP----PPVQATPHPFPAVTPDLIVQTPV 238
            TGT  P  + +  TT  +   TP  TQTP   P      V  TP P    TP     T  
Sbjct: 3064 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3123

Query: 239  MTVVP---PQPLQTPPPVPPQPQPPPAPAPQPVQSHPP-------IIAATPQPVKTKKGV 288
             TV P   P   QTP   P        P P P  +  P           TP P  T    
Sbjct: 3124 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3183

Query: 289  KRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
                  TT TT+ P   P     P+  P   TT
Sbjct: 3184 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3216



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 46/153 (30%), Positives = 52/153 (33%), Gaps = 22/153 (14%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP----PPVQATPHPFPAVTPDLIVQTPV 238
            TGT  P  + +  TT  +   TP  TQTP   P      V  TP P    TP     T  
Sbjct: 3133 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3192

Query: 239  MTVVP---PQPLQTPPPVPPQPQPPPAPAPQPVQSHPP-------IIAATPQPVKTKKGV 288
             TV P   P   QTP   P        P P P  +  P           TP P  T    
Sbjct: 3193 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3252

Query: 289  KRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
                  TT TT+ P   P     P+  P   TT
Sbjct: 3253 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3285



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 46/153 (30%), Positives = 52/153 (33%), Gaps = 22/153 (14%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP----PPVQATPHPFPAVTPDLIVQTPV 238
            TGT  P  + +  TT  +   TP  TQTP   P      V  TP P    TP     T  
Sbjct: 3202 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3261

Query: 239  MTVVP---PQPLQTPPPVPPQPQPPPAPAPQPVQSHPP-------IIAATPQPVKTKKGV 288
             TV P   P   QTP   P        P P P  +  P           TP P  T    
Sbjct: 3262 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3321

Query: 289  KRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
                  TT TT+ P   P     P+  P   TT
Sbjct: 3322 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3354



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 46/153 (30%), Positives = 52/153 (33%), Gaps = 22/153 (14%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP----PPVQATPHPFPAVTPDLIVQTPV 238
            TGT  P  + +  TT  +   TP  TQTP   P      V  TP P    TP     T  
Sbjct: 3271 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3330

Query: 239  MTVVP---PQPLQTPPPVPPQPQPPPAPAPQPVQSHPP-------IIAATPQPVKTKKGV 288
             TV P   P   QTP   P        P P P  +  P           TP P  T    
Sbjct: 3331 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3390

Query: 289  KRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
                  TT TT+ P   P     P+  P   TT
Sbjct: 3391 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3423



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 46/153 (30%), Positives = 52/153 (33%), Gaps = 22/153 (14%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP----PPVQATPHPFPAVTPDLIVQTPV 238
            TGT  P  + +  TT  +   TP  TQTP   P      V  TP P    TP     T  
Sbjct: 3340 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3399

Query: 239  MTVVP---PQPLQTPPPVPPQPQPPPAPAPQPVQSHPP-------IIAATPQPVKTKKGV 288
             TV P   P   QTP   P        P P P  +  P           TP P  T    
Sbjct: 3400 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3459

Query: 289  KRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
                  TT TT+ P   P     P+  P   TT
Sbjct: 3460 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3492



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 46/153 (30%), Positives = 52/153 (33%), Gaps = 22/153 (14%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP----PPVQATPHPFPAVTPDLIVQTPV 238
            TGT  P  + +  TT  +   TP  TQTP   P      V  TP P    TP     T  
Sbjct: 3409 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3468

Query: 239  MTVVP---PQPLQTPPPVPPQPQPPPAPAPQPVQSHPP-------IIAATPQPVKTKKGV 288
             TV P   P   QTP   P        P P P  +  P           TP P  T    
Sbjct: 3469 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3528

Query: 289  KRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
                  TT TT+ P   P     P+  P   TT
Sbjct: 3529 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3561



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 46/153 (30%), Positives = 52/153 (33%), Gaps = 22/153 (14%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP----PPVQATPHPFPAVTPDLIVQTPV 238
            TGT  P  + +  TT  +   TP  TQTP   P      V  TP P    TP     T  
Sbjct: 3478 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3537

Query: 239  MTVVP---PQPLQTPPPVPPQPQPPPAPAPQPVQSHPP-------IIAATPQPVKTKKGV 288
             TV P   P   QTP   P        P P P  +  P           TP P  T    
Sbjct: 3538 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3597

Query: 289  KRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
                  TT TT+ P   P     P+  P   TT
Sbjct: 3598 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3630



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 46/153 (30%), Positives = 52/153 (33%), Gaps = 22/153 (14%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP----PPVQATPHPFPAVTPDLIVQTPV 238
            TGT  P  + +  TT  +   TP  TQTP   P      V  TP P    TP     T  
Sbjct: 3547 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3606

Query: 239  MTVVP---PQPLQTPPPVPPQPQPPPAPAPQPVQSHPP-------IIAATPQPVKTKKGV 288
             TV P   P   QTP   P        P P P  +  P           TP P  T    
Sbjct: 3607 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3666

Query: 289  KRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
                  TT TT+ P   P     P+  P   TT
Sbjct: 3667 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3699



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 46/153 (30%), Positives = 52/153 (33%), Gaps = 22/153 (14%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP----PPVQATPHPFPAVTPDLIVQTPV 238
            TGT  P  + +  TT  +   TP  TQTP   P      V  TP P    TP     T  
Sbjct: 3616 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3675

Query: 239  MTVVP---PQPLQTPPPVPPQPQPPPAPAPQPVQSHPP-------IIAATPQPVKTKKGV 288
             TV P   P   QTP   P        P P P  +  P           TP P  T    
Sbjct: 3676 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3735

Query: 289  KRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
                  TT TT+ P   P     P+  P   TT
Sbjct: 3736 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3768



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 46/153 (30%), Positives = 52/153 (33%), Gaps = 22/153 (14%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP----PPVQATPHPFPAVTPDLIVQTPV 238
            TGT  P  + +  TT  +   TP  TQTP   P      V  TP P    TP     T  
Sbjct: 3685 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3744

Query: 239  MTVVP---PQPLQTPPPVPPQPQPPPAPAPQPVQSHPP-------IIAATPQPVKTKKGV 288
             TV P   P   QTP   P        P P P  +  P           TP P  T    
Sbjct: 3745 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3804

Query: 289  KRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
                  TT TT+ P   P     P+  P   TT
Sbjct: 3805 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3837



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 46/153 (30%), Positives = 52/153 (33%), Gaps = 22/153 (14%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP----PPVQATPHPFPAVTPDLIVQTPV 238
            TGT  P  + +  TT  +   TP  TQTP   P      V  TP P    TP     T  
Sbjct: 3754 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3813

Query: 239  MTVVP---PQPLQTPPPVPPQPQPPPAPAPQPVQSHPP-------IIAATPQPVKTKKGV 288
             TV P   P   QTP   P        P P P  +  P           TP P  T    
Sbjct: 3814 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3873

Query: 289  KRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
                  TT TT+ P   P     P+  P   TT
Sbjct: 3874 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3906



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 46/153 (30%), Positives = 52/153 (33%), Gaps = 22/153 (14%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP----PPVQATPHPFPAVTPDLIVQTPV 238
            TGT  P  + +  TT  +   TP  TQTP   P      V  TP P    TP     T  
Sbjct: 3823 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3882

Query: 239  MTVVP---PQPLQTPPPVPPQPQPPPAPAPQPVQSHPP-------IIAATPQPVKTKKGV 288
             TV P   P   QTP   P        P P P  +  P           TP P  T    
Sbjct: 3883 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3942

Query: 289  KRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
                  TT TT+ P   P     P+  P   TT
Sbjct: 3943 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3975



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 46/153 (30%), Positives = 52/153 (33%), Gaps = 22/153 (14%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP----PPVQATPHPFPAVTPDLIVQTPV 238
            TGT  P  + +  TT  +   TP  TQTP   P      V  TP P    TP     T  
Sbjct: 3892 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3951

Query: 239  MTVVP---PQPLQTPPPVPPQPQPPPAPAPQPVQSHPP-------IIAATPQPVKTKKGV 288
             TV P   P   QTP   P        P P P  +  P           TP P  T    
Sbjct: 3952 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 4011

Query: 289  KRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
                  TT TT+ P   P     P+  P   TT
Sbjct: 4012 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 4044



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 46/153 (30%), Positives = 52/153 (33%), Gaps = 22/153 (14%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP----PPVQATPHPFPAVTPDLIVQTPV 238
            TGT  P  + +  TT  +   TP  TQTP   P      V  TP P    TP     T  
Sbjct: 3961 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 4020

Query: 239  MTVVP---PQPLQTPPPVPPQPQPPPAPAPQPVQSHPP-------IIAATPQPVKTKKGV 288
             TV P   P   QTP   P        P P P  +  P           TP P  T    
Sbjct: 4021 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 4080

Query: 289  KRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
                  TT TT+ P   P     P+  P   TT
Sbjct: 4081 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 4113



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 46/153 (30%), Positives = 52/153 (33%), Gaps = 22/153 (14%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP----PPVQATPHPFPAVTPDLIVQTPV 238
            TGT  P  + +  TT  +   TP  TQTP   P      V  TP P    TP     T  
Sbjct: 4030 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 4089

Query: 239  MTVVP---PQPLQTPPPVPPQPQPPPAPAPQPVQSHPP-------IIAATPQPVKTKKGV 288
             TV P   P   QTP   P        P P P  +  P           TP P  T    
Sbjct: 4090 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 4149

Query: 289  KRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
                  TT TT+ P   P     P+  P   TT
Sbjct: 4150 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 4182



 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 41/158 (25%), Positives = 58/158 (36%), Gaps = 25/158 (15%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQP--------------NPPPVQATPHPFPAV 228
            TGT  P  + +  TT  +   TP  TQT  P              NPPP  +TP    + 
Sbjct: 4168 TGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRST 4227

Query: 229  TPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGV 288
            +  L   T +++ +PP    T    P  P  P   +     S PP    +P    T+   
Sbjct: 4228 SSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTT 4287

Query: 289  KRKADTTTPTTID--------PIHEPPSLPPEPKTTKL 318
               +   TP+T+         P   P S P   +TT L
Sbjct: 4288 TGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGL 4325



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 46/158 (29%), Positives = 53/158 (33%), Gaps = 32/158 (20%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP--PPVQATPHPFPAVTPDLIVQTPVMT 240
            TGT  P  + +  TT  +   TP  TQTP   P       TP P P  T     QTP  T
Sbjct: 1914 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTT 1968

Query: 241  VVPPQPLQTPPPVPPQPQPPP----------APAPQPVQSHPP-------IIAATPQPVK 283
             +      TP P P   Q P            P P P  +  P           TP P  
Sbjct: 1969 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2028

Query: 284  TKKGVKRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
            T          TT TT+ P   P     P+  P   TT
Sbjct: 2029 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2066



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 46/158 (29%), Positives = 53/158 (33%), Gaps = 32/158 (20%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP--PPVQATPHPFPAVTPDLIVQTPVMT 240
            TGT  P  + +  TT  +   TP  TQTP   P       TP P P  T     QTP  T
Sbjct: 1937 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTT 1991

Query: 241  VVPPQPLQTPPPVPPQPQPPP----------APAPQPVQSHPP-------IIAATPQPVK 283
             +      TP P P   Q P            P P P  +  P           TP P  
Sbjct: 1992 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2051

Query: 284  TKKGVKRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
            T          TT TT+ P   P     P+  P   TT
Sbjct: 2052 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2089



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 46/158 (29%), Positives = 53/158 (33%), Gaps = 32/158 (20%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP--PPVQATPHPFPAVTPDLIVQTPVMT 240
            TGT  P  + +  TT  +   TP  TQTP   P       TP P P  T     QTP  T
Sbjct: 1983 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTT 2037

Query: 241  VVPPQPLQTPPPVPPQPQPPP----------APAPQPVQSHPP-------IIAATPQPVK 283
             +      TP P P   Q P            P P P  +  P           TP P  
Sbjct: 2038 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2097

Query: 284  TKKGVKRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
            T          TT TT+ P   P     P+  P   TT
Sbjct: 2098 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2135



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 46/158 (29%), Positives = 53/158 (33%), Gaps = 32/158 (20%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP--PPVQATPHPFPAVTPDLIVQTPVMT 240
            TGT  P  + +  TT  +   TP  TQTP   P       TP P P  T     QTP  T
Sbjct: 2006 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTT 2060

Query: 241  VVPPQPLQTPPPVPPQPQPPP----------APAPQPVQSHPP-------IIAATPQPVK 283
             +      TP P P   Q P            P P P  +  P           TP P  
Sbjct: 2061 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2120

Query: 284  TKKGVKRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
            T          TT TT+ P   P     P+  P   TT
Sbjct: 2121 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2158



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 46/158 (29%), Positives = 53/158 (33%), Gaps = 32/158 (20%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP--PPVQATPHPFPAVTPDLIVQTPVMT 240
            TGT  P  + +  TT  +   TP  TQTP   P       TP P P  T     QTP  T
Sbjct: 2052 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTT 2106

Query: 241  VVPPQPLQTPPPVPPQPQPPP----------APAPQPVQSHPP-------IIAATPQPVK 283
             +      TP P P   Q P            P P P  +  P           TP P  
Sbjct: 2107 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2166

Query: 284  TKKGVKRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
            T          TT TT+ P   P     P+  P   TT
Sbjct: 2167 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2204



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 46/158 (29%), Positives = 53/158 (33%), Gaps = 32/158 (20%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP--PPVQATPHPFPAVTPDLIVQTPVMT 240
            TGT  P  + +  TT  +   TP  TQTP   P       TP P P  T     QTP  T
Sbjct: 2075 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTT 2129

Query: 241  VVPPQPLQTPPPVPPQPQPPP----------APAPQPVQSHPP-------IIAATPQPVK 283
             +      TP P P   Q P            P P P  +  P           TP P  
Sbjct: 2130 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2189

Query: 284  TKKGVKRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
            T          TT TT+ P   P     P+  P   TT
Sbjct: 2190 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2227



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 46/158 (29%), Positives = 53/158 (33%), Gaps = 32/158 (20%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP--PPVQATPHPFPAVTPDLIVQTPVMT 240
            TGT  P  + +  TT  +   TP  TQTP   P       TP P P  T     QTP  T
Sbjct: 2121 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTT 2175

Query: 241  VVPPQPLQTPPPVPPQPQPPP----------APAPQPVQSHPP-------IIAATPQPVK 283
             +      TP P P   Q P            P P P  +  P           TP P  
Sbjct: 2176 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2235

Query: 284  TKKGVKRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
            T          TT TT+ P   P     P+  P   TT
Sbjct: 2236 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2273



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 46/158 (29%), Positives = 53/158 (33%), Gaps = 32/158 (20%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP--PPVQATPHPFPAVTPDLIVQTPVMT 240
            TGT  P  + +  TT  +   TP  TQTP   P       TP P P  T     QTP  T
Sbjct: 2144 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTT 2198

Query: 241  VVPPQPLQTPPPVPPQPQPPP----------APAPQPVQSHPP-------IIAATPQPVK 283
             +      TP P P   Q P            P P P  +  P           TP P  
Sbjct: 2199 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2258

Query: 284  TKKGVKRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
            T          TT TT+ P   P     P+  P   TT
Sbjct: 2259 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2296



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 46/158 (29%), Positives = 53/158 (33%), Gaps = 32/158 (20%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP--PPVQATPHPFPAVTPDLIVQTPVMT 240
            TGT  P  + +  TT  +   TP  TQTP   P       TP P P  T     QTP  T
Sbjct: 2190 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTT 2244

Query: 241  VVPPQPLQTPPPVPPQPQPPP----------APAPQPVQSHPP-------IIAATPQPVK 283
             +      TP P P   Q P            P P P  +  P           TP P  
Sbjct: 2245 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2304

Query: 284  TKKGVKRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
            T          TT TT+ P   P     P+  P   TT
Sbjct: 2305 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2342



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 46/158 (29%), Positives = 53/158 (33%), Gaps = 32/158 (20%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP--PPVQATPHPFPAVTPDLIVQTPVMT 240
            TGT  P  + +  TT  +   TP  TQTP   P       TP P P  T     QTP  T
Sbjct: 2213 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTT 2267

Query: 241  VVPPQPLQTPPPVPPQPQPPP----------APAPQPVQSHPP-------IIAATPQPVK 283
             +      TP P P   Q P            P P P  +  P           TP P  
Sbjct: 2268 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2327

Query: 284  TKKGVKRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
            T          TT TT+ P   P     P+  P   TT
Sbjct: 2328 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2365



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 46/158 (29%), Positives = 53/158 (33%), Gaps = 32/158 (20%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP--PPVQATPHPFPAVTPDLIVQTPVMT 240
            TGT  P  + +  TT  +   TP  TQTP   P       TP P P  T     QTP  T
Sbjct: 2259 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTT 2313

Query: 241  VVPPQPLQTPPPVPPQPQPPP----------APAPQPVQSHPP-------IIAATPQPVK 283
             +      TP P P   Q P            P P P  +  P           TP P  
Sbjct: 2314 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2373

Query: 284  TKKGVKRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
            T          TT TT+ P   P     P+  P   TT
Sbjct: 2374 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2411



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 46/158 (29%), Positives = 53/158 (33%), Gaps = 32/158 (20%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP--PPVQATPHPFPAVTPDLIVQTPVMT 240
            TGT  P  + +  TT  +   TP  TQTP   P       TP P P  T     QTP  T
Sbjct: 2282 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTT 2336

Query: 241  VVPPQPLQTPPPVPPQPQPPP----------APAPQPVQSHPP-------IIAATPQPVK 283
             +      TP P P   Q P            P P P  +  P           TP P  
Sbjct: 2337 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2396

Query: 284  TKKGVKRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
            T          TT TT+ P   P     P+  P   TT
Sbjct: 2397 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2434



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 46/158 (29%), Positives = 53/158 (33%), Gaps = 32/158 (20%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP--PPVQATPHPFPAVTPDLIVQTPVMT 240
            TGT  P  + +  TT  +   TP  TQTP   P       TP P P  T     QTP  T
Sbjct: 2328 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTT 2382

Query: 241  VVPPQPLQTPPPVPPQPQPPP----------APAPQPVQSHPP-------IIAATPQPVK 283
             +      TP P P   Q P            P P P  +  P           TP P  
Sbjct: 2383 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2442

Query: 284  TKKGVKRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
            T          TT TT+ P   P     P+  P   TT
Sbjct: 2443 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2480



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 46/158 (29%), Positives = 53/158 (33%), Gaps = 32/158 (20%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP--PPVQATPHPFPAVTPDLIVQTPVMT 240
            TGT  P  + +  TT  +   TP  TQTP   P       TP P P  T     QTP  T
Sbjct: 2351 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTT 2405

Query: 241  VVPPQPLQTPPPVPPQPQPPP----------APAPQPVQSHPP-------IIAATPQPVK 283
             +      TP P P   Q P            P P P  +  P           TP P  
Sbjct: 2406 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2465

Query: 284  TKKGVKRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
            T          TT TT+ P   P     P+  P   TT
Sbjct: 2466 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2503



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 46/158 (29%), Positives = 53/158 (33%), Gaps = 32/158 (20%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP--PPVQATPHPFPAVTPDLIVQTPVMT 240
            TGT  P  + +  TT  +   TP  TQTP   P       TP P P  T     QTP  T
Sbjct: 2397 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTT 2451

Query: 241  VVPPQPLQTPPPVPPQPQPPP----------APAPQPVQSHPP-------IIAATPQPVK 283
             +      TP P P   Q P            P P P  +  P           TP P  
Sbjct: 2452 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2511

Query: 284  TKKGVKRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
            T          TT TT+ P   P     P+  P   TT
Sbjct: 2512 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2549



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 46/158 (29%), Positives = 53/158 (33%), Gaps = 32/158 (20%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP--PPVQATPHPFPAVTPDLIVQTPVMT 240
            TGT  P  + +  TT  +   TP  TQTP   P       TP P P  T     QTP  T
Sbjct: 2420 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTT 2474

Query: 241  VVPPQPLQTPPPVPPQPQPPP----------APAPQPVQSHPP-------IIAATPQPVK 283
             +      TP P P   Q P            P P P  +  P           TP P  
Sbjct: 2475 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2534

Query: 284  TKKGVKRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
            T          TT TT+ P   P     P+  P   TT
Sbjct: 2535 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2572



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 46/158 (29%), Positives = 53/158 (33%), Gaps = 32/158 (20%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP--PPVQATPHPFPAVTPDLIVQTPVMT 240
            TGT  P  + +  TT  +   TP  TQTP   P       TP P P  T     QTP  T
Sbjct: 2466 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTT 2520

Query: 241  VVPPQPLQTPPPVPPQPQPPP----------APAPQPVQSHPP-------IIAATPQPVK 283
             +      TP P P   Q P            P P P  +  P           TP P  
Sbjct: 2521 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2580

Query: 284  TKKGVKRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
            T          TT TT+ P   P     P+  P   TT
Sbjct: 2581 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2618



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 46/158 (29%), Positives = 53/158 (33%), Gaps = 32/158 (20%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP--PPVQATPHPFPAVTPDLIVQTPVMT 240
            TGT  P  + +  TT  +   TP  TQTP   P       TP P P  T     QTP  T
Sbjct: 2489 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTT 2543

Query: 241  VVPPQPLQTPPPVPPQPQPPP----------APAPQPVQSHPP-------IIAATPQPVK 283
             +      TP P P   Q P            P P P  +  P           TP P  
Sbjct: 2544 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2603

Query: 284  TKKGVKRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
            T          TT TT+ P   P     P+  P   TT
Sbjct: 2604 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2641



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 46/158 (29%), Positives = 53/158 (33%), Gaps = 32/158 (20%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP--PPVQATPHPFPAVTPDLIVQTPVMT 240
            TGT  P  + +  TT  +   TP  TQTP   P       TP P P  T     QTP  T
Sbjct: 2535 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTT 2589

Query: 241  VVPPQPLQTPPPVPPQPQPPP----------APAPQPVQSHPP-------IIAATPQPVK 283
             +      TP P P   Q P            P P P  +  P           TP P  
Sbjct: 2590 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2649

Query: 284  TKKGVKRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
            T          TT TT+ P   P     P+  P   TT
Sbjct: 2650 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2687



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 46/158 (29%), Positives = 53/158 (33%), Gaps = 32/158 (20%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP--PPVQATPHPFPAVTPDLIVQTPVMT 240
            TGT  P  + +  TT  +   TP  TQTP   P       TP P P  T     QTP  T
Sbjct: 2558 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTT 2612

Query: 241  VVPPQPLQTPPPVPPQPQPPP----------APAPQPVQSHPP-------IIAATPQPVK 283
             +      TP P P   Q P            P P P  +  P           TP P  
Sbjct: 2613 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2672

Query: 284  TKKGVKRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
            T          TT TT+ P   P     P+  P   TT
Sbjct: 2673 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2710



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 46/158 (29%), Positives = 53/158 (33%), Gaps = 32/158 (20%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP--PPVQATPHPFPAVTPDLIVQTPVMT 240
            TGT  P  + +  TT  +   TP  TQTP   P       TP P P  T     QTP  T
Sbjct: 2604 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTT 2658

Query: 241  VVPPQPLQTPPPVPPQPQPPP----------APAPQPVQSHPP-------IIAATPQPVK 283
             +      TP P P   Q P            P P P  +  P           TP P  
Sbjct: 2659 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2718

Query: 284  TKKGVKRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
            T          TT TT+ P   P     P+  P   TT
Sbjct: 2719 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2756



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 46/158 (29%), Positives = 53/158 (33%), Gaps = 32/158 (20%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP--PPVQATPHPFPAVTPDLIVQTPVMT 240
            TGT  P  + +  TT  +   TP  TQTP   P       TP P P  T     QTP  T
Sbjct: 2627 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTT 2681

Query: 241  VVPPQPLQTPPPVPPQPQPPP----------APAPQPVQSHPP-------IIAATPQPVK 283
             +      TP P P   Q P            P P P  +  P           TP P  
Sbjct: 2682 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2741

Query: 284  TKKGVKRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
            T          TT TT+ P   P     P+  P   TT
Sbjct: 2742 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2779



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 46/158 (29%), Positives = 53/158 (33%), Gaps = 32/158 (20%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP--PPVQATPHPFPAVTPDLIVQTPVMT 240
            TGT  P  + +  TT  +   TP  TQTP   P       TP P P  T     QTP  T
Sbjct: 2673 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTT 2727

Query: 241  VVPPQPLQTPPPVPPQPQPPP----------APAPQPVQSHPP-------IIAATPQPVK 283
             +      TP P P   Q P            P P P  +  P           TP P  
Sbjct: 2728 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2787

Query: 284  TKKGVKRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
            T          TT TT+ P   P     P+  P   TT
Sbjct: 2788 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2825



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 46/158 (29%), Positives = 53/158 (33%), Gaps = 32/158 (20%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP--PPVQATPHPFPAVTPDLIVQTPVMT 240
            TGT  P  + +  TT  +   TP  TQTP   P       TP P P  T     QTP  T
Sbjct: 2696 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTT 2750

Query: 241  VVPPQPLQTPPPVPPQPQPPP----------APAPQPVQSHPP-------IIAATPQPVK 283
             +      TP P P   Q P            P P P  +  P           TP P  
Sbjct: 2751 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2810

Query: 284  TKKGVKRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
            T          TT TT+ P   P     P+  P   TT
Sbjct: 2811 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2848



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 46/158 (29%), Positives = 53/158 (33%), Gaps = 32/158 (20%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP--PPVQATPHPFPAVTPDLIVQTPVMT 240
            TGT  P  + +  TT  +   TP  TQTP   P       TP P P  T     QTP  T
Sbjct: 2742 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTT 2796

Query: 241  VVPPQPLQTPPPVPPQPQPPP----------APAPQPVQSHPP-------IIAATPQPVK 283
             +      TP P P   Q P            P P P  +  P           TP P  
Sbjct: 2797 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2856

Query: 284  TKKGVKRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
            T          TT TT+ P   P     P+  P   TT
Sbjct: 2857 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2894



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 46/158 (29%), Positives = 53/158 (33%), Gaps = 32/158 (20%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP--PPVQATPHPFPAVTPDLIVQTPVMT 240
            TGT  P  + +  TT  +   TP  TQTP   P       TP P P  T     QTP  T
Sbjct: 2765 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTT 2819

Query: 241  VVPPQPLQTPPPVPPQPQPPP----------APAPQPVQSHPP-------IIAATPQPVK 283
             +      TP P P   Q P            P P P  +  P           TP P  
Sbjct: 2820 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2879

Query: 284  TKKGVKRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
            T          TT TT+ P   P     P+  P   TT
Sbjct: 2880 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2917



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 46/158 (29%), Positives = 53/158 (33%), Gaps = 32/158 (20%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP--PPVQATPHPFPAVTPDLIVQTPVMT 240
            TGT  P  + +  TT  +   TP  TQTP   P       TP P P  T     QTP  T
Sbjct: 2811 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTT 2865

Query: 241  VVPPQPLQTPPPVPPQPQPPP----------APAPQPVQSHPP-------IIAATPQPVK 283
             +      TP P P   Q P            P P P  +  P           TP P  
Sbjct: 2866 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2925

Query: 284  TKKGVKRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
            T          TT TT+ P   P     P+  P   TT
Sbjct: 2926 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2963



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 46/158 (29%), Positives = 53/158 (33%), Gaps = 32/158 (20%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP--PPVQATPHPFPAVTPDLIVQTPVMT 240
            TGT  P  + +  TT  +   TP  TQTP   P       TP P P  T     QTP  T
Sbjct: 2834 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTT 2888

Query: 241  VVPPQPLQTPPPVPPQPQPPP----------APAPQPVQSHPP-------IIAATPQPVK 283
             +      TP P P   Q P            P P P  +  P           TP P  
Sbjct: 2889 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2948

Query: 284  TKKGVKRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
            T          TT TT+ P   P     P+  P   TT
Sbjct: 2949 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2986



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 46/158 (29%), Positives = 53/158 (33%), Gaps = 32/158 (20%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP--PPVQATPHPFPAVTPDLIVQTPVMT 240
            TGT  P  + +  TT  +   TP  TQTP   P       TP P P  T     QTP  T
Sbjct: 2880 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTT 2934

Query: 241  VVPPQPLQTPPPVPPQPQPPP----------APAPQPVQSHPP-------IIAATPQPVK 283
             +      TP P P   Q P            P P P  +  P           TP P  
Sbjct: 2935 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2994

Query: 284  TKKGVKRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
            T          TT TT+ P   P     P+  P   TT
Sbjct: 2995 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3032



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 46/158 (29%), Positives = 53/158 (33%), Gaps = 32/158 (20%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP--PPVQATPHPFPAVTPDLIVQTPVMT 240
            TGT  P  + +  TT  +   TP  TQTP   P       TP P P  T     QTP  T
Sbjct: 2903 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTT 2957

Query: 241  VVPPQPLQTPPPVPPQPQPPP----------APAPQPVQSHPP-------IIAATPQPVK 283
             +      TP P P   Q P            P P P  +  P           TP P  
Sbjct: 2958 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3017

Query: 284  TKKGVKRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
            T          TT TT+ P   P     P+  P   TT
Sbjct: 3018 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3055



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 46/158 (29%), Positives = 53/158 (33%), Gaps = 32/158 (20%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP--PPVQATPHPFPAVTPDLIVQTPVMT 240
            TGT  P  + +  TT  +   TP  TQTP   P       TP P P  T     QTP  T
Sbjct: 2949 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTT 3003

Query: 241  VVPPQPLQTPPPVPPQPQPPP----------APAPQPVQSHPP-------IIAATPQPVK 283
             +      TP P P   Q P            P P P  +  P           TP P  
Sbjct: 3004 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3063

Query: 284  TKKGVKRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
            T          TT TT+ P   P     P+  P   TT
Sbjct: 3064 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3101



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 46/158 (29%), Positives = 53/158 (33%), Gaps = 32/158 (20%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP--PPVQATPHPFPAVTPDLIVQTPVMT 240
            TGT  P  + +  TT  +   TP  TQTP   P       TP P P  T     QTP  T
Sbjct: 2972 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTT 3026

Query: 241  VVPPQPLQTPPPVPPQPQPPP----------APAPQPVQSHPP-------IIAATPQPVK 283
             +      TP P P   Q P            P P P  +  P           TP P  
Sbjct: 3027 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3086

Query: 284  TKKGVKRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
            T          TT TT+ P   P     P+  P   TT
Sbjct: 3087 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3124



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 46/158 (29%), Positives = 53/158 (33%), Gaps = 32/158 (20%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP--PPVQATPHPFPAVTPDLIVQTPVMT 240
            TGT  P  + +  TT  +   TP  TQTP   P       TP P P  T     QTP  T
Sbjct: 3018 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTT 3072

Query: 241  VVPPQPLQTPPPVPPQPQPPP----------APAPQPVQSHPP-------IIAATPQPVK 283
             +      TP P P   Q P            P P P  +  P           TP P  
Sbjct: 3073 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3132

Query: 284  TKKGVKRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
            T          TT TT+ P   P     P+  P   TT
Sbjct: 3133 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3170



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 46/158 (29%), Positives = 53/158 (33%), Gaps = 32/158 (20%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP--PPVQATPHPFPAVTPDLIVQTPVMT 240
            TGT  P  + +  TT  +   TP  TQTP   P       TP P P  T     QTP  T
Sbjct: 3041 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTT 3095

Query: 241  VVPPQPLQTPPPVPPQPQPPP----------APAPQPVQSHPP-------IIAATPQPVK 283
             +      TP P P   Q P            P P P  +  P           TP P  
Sbjct: 3096 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3155

Query: 284  TKKGVKRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
            T          TT TT+ P   P     P+  P   TT
Sbjct: 3156 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3193



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 46/158 (29%), Positives = 53/158 (33%), Gaps = 32/158 (20%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP--PPVQATPHPFPAVTPDLIVQTPVMT 240
            TGT  P  + +  TT  +   TP  TQTP   P       TP P P  T     QTP  T
Sbjct: 3087 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTT 3141

Query: 241  VVPPQPLQTPPPVPPQPQPPP----------APAPQPVQSHPP-------IIAATPQPVK 283
             +      TP P P   Q P            P P P  +  P           TP P  
Sbjct: 3142 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3201

Query: 284  TKKGVKRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
            T          TT TT+ P   P     P+  P   TT
Sbjct: 3202 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3239



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 46/158 (29%), Positives = 53/158 (33%), Gaps = 32/158 (20%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP--PPVQATPHPFPAVTPDLIVQTPVMT 240
            TGT  P  + +  TT  +   TP  TQTP   P       TP P P  T     QTP  T
Sbjct: 3110 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTT 3164

Query: 241  VVPPQPLQTPPPVPPQPQPPP----------APAPQPVQSHPP-------IIAATPQPVK 283
             +      TP P P   Q P            P P P  +  P           TP P  
Sbjct: 3165 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3224

Query: 284  TKKGVKRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
            T          TT TT+ P   P     P+  P   TT
Sbjct: 3225 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3262



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 46/158 (29%), Positives = 53/158 (33%), Gaps = 32/158 (20%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP--PPVQATPHPFPAVTPDLIVQTPVMT 240
            TGT  P  + +  TT  +   TP  TQTP   P       TP P P  T     QTP  T
Sbjct: 3156 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTT 3210

Query: 241  VVPPQPLQTPPPVPPQPQPPP----------APAPQPVQSHPP-------IIAATPQPVK 283
             +      TP P P   Q P            P P P  +  P           TP P  
Sbjct: 3211 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3270

Query: 284  TKKGVKRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
            T          TT TT+ P   P     P+  P   TT
Sbjct: 3271 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3308



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 46/158 (29%), Positives = 53/158 (33%), Gaps = 32/158 (20%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP--PPVQATPHPFPAVTPDLIVQTPVMT 240
            TGT  P  + +  TT  +   TP  TQTP   P       TP P P  T     QTP  T
Sbjct: 3179 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTT 3233

Query: 241  VVPPQPLQTPPPVPPQPQPPP----------APAPQPVQSHPP-------IIAATPQPVK 283
             +      TP P P   Q P            P P P  +  P           TP P  
Sbjct: 3234 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3293

Query: 284  TKKGVKRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
            T          TT TT+ P   P     P+  P   TT
Sbjct: 3294 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3331



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 46/158 (29%), Positives = 53/158 (33%), Gaps = 32/158 (20%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP--PPVQATPHPFPAVTPDLIVQTPVMT 240
            TGT  P  + +  TT  +   TP  TQTP   P       TP P P  T     QTP  T
Sbjct: 3225 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTT 3279

Query: 241  VVPPQPLQTPPPVPPQPQPPP----------APAPQPVQSHPP-------IIAATPQPVK 283
             +      TP P P   Q P            P P P  +  P           TP P  
Sbjct: 3280 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3339

Query: 284  TKKGVKRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
            T          TT TT+ P   P     P+  P   TT
Sbjct: 3340 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3377



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 46/158 (29%), Positives = 53/158 (33%), Gaps = 32/158 (20%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP--PPVQATPHPFPAVTPDLIVQTPVMT 240
            TGT  P  + +  TT  +   TP  TQTP   P       TP P P  T     QTP  T
Sbjct: 3248 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTT 3302

Query: 241  VVPPQPLQTPPPVPPQPQPPP----------APAPQPVQSHPP-------IIAATPQPVK 283
             +      TP P P   Q P            P P P  +  P           TP P  
Sbjct: 3303 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3362

Query: 284  TKKGVKRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
            T          TT TT+ P   P     P+  P   TT
Sbjct: 3363 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3400



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 46/158 (29%), Positives = 53/158 (33%), Gaps = 32/158 (20%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP--PPVQATPHPFPAVTPDLIVQTPVMT 240
            TGT  P  + +  TT  +   TP  TQTP   P       TP P P  T     QTP  T
Sbjct: 3294 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTT 3348

Query: 241  VVPPQPLQTPPPVPPQPQPPP----------APAPQPVQSHPP-------IIAATPQPVK 283
             +      TP P P   Q P            P P P  +  P           TP P  
Sbjct: 3349 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3408

Query: 284  TKKGVKRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
            T          TT TT+ P   P     P+  P   TT
Sbjct: 3409 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3446



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 46/158 (29%), Positives = 53/158 (33%), Gaps = 32/158 (20%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP--PPVQATPHPFPAVTPDLIVQTPVMT 240
            TGT  P  + +  TT  +   TP  TQTP   P       TP P P  T     QTP  T
Sbjct: 3317 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTT 3371

Query: 241  VVPPQPLQTPPPVPPQPQPPP----------APAPQPVQSHPP-------IIAATPQPVK 283
             +      TP P P   Q P            P P P  +  P           TP P  
Sbjct: 3372 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3431

Query: 284  TKKGVKRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
            T          TT TT+ P   P     P+  P   TT
Sbjct: 3432 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3469



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 46/158 (29%), Positives = 53/158 (33%), Gaps = 32/158 (20%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP--PPVQATPHPFPAVTPDLIVQTPVMT 240
            TGT  P  + +  TT  +   TP  TQTP   P       TP P P  T     QTP  T
Sbjct: 3363 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTT 3417

Query: 241  VVPPQPLQTPPPVPPQPQPPP----------APAPQPVQSHPP-------IIAATPQPVK 283
             +      TP P P   Q P            P P P  +  P           TP P  
Sbjct: 3418 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3477

Query: 284  TKKGVKRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
            T          TT TT+ P   P     P+  P   TT
Sbjct: 3478 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3515



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 46/158 (29%), Positives = 53/158 (33%), Gaps = 32/158 (20%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP--PPVQATPHPFPAVTPDLIVQTPVMT 240
            TGT  P  + +  TT  +   TP  TQTP   P       TP P P  T     QTP  T
Sbjct: 3386 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTT 3440

Query: 241  VVPPQPLQTPPPVPPQPQPPP----------APAPQPVQSHPP-------IIAATPQPVK 283
             +      TP P P   Q P            P P P  +  P           TP P  
Sbjct: 3441 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3500

Query: 284  TKKGVKRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
            T          TT TT+ P   P     P+  P   TT
Sbjct: 3501 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3538



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 46/158 (29%), Positives = 53/158 (33%), Gaps = 32/158 (20%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP--PPVQATPHPFPAVTPDLIVQTPVMT 240
            TGT  P  + +  TT  +   TP  TQTP   P       TP P P  T     QTP  T
Sbjct: 3432 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTT 3486

Query: 241  VVPPQPLQTPPPVPPQPQPPP----------APAPQPVQSHPP-------IIAATPQPVK 283
             +      TP P P   Q P            P P P  +  P           TP P  
Sbjct: 3487 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3546

Query: 284  TKKGVKRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
            T          TT TT+ P   P     P+  P   TT
Sbjct: 3547 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3584



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 46/158 (29%), Positives = 53/158 (33%), Gaps = 32/158 (20%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP--PPVQATPHPFPAVTPDLIVQTPVMT 240
            TGT  P  + +  TT  +   TP  TQTP   P       TP P P  T     QTP  T
Sbjct: 3455 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTT 3509

Query: 241  VVPPQPLQTPPPVPPQPQPPP----------APAPQPVQSHPP-------IIAATPQPVK 283
             +      TP P P   Q P            P P P  +  P           TP P  
Sbjct: 3510 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3569

Query: 284  TKKGVKRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
            T          TT TT+ P   P     P+  P   TT
Sbjct: 3570 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3607



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 46/158 (29%), Positives = 53/158 (33%), Gaps = 32/158 (20%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP--PPVQATPHPFPAVTPDLIVQTPVMT 240
            TGT  P  + +  TT  +   TP  TQTP   P       TP P P  T     QTP  T
Sbjct: 3501 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTT 3555

Query: 241  VVPPQPLQTPPPVPPQPQPPP----------APAPQPVQSHPP-------IIAATPQPVK 283
             +      TP P P   Q P            P P P  +  P           TP P  
Sbjct: 3556 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3615

Query: 284  TKKGVKRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
            T          TT TT+ P   P     P+  P   TT
Sbjct: 3616 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3653



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 46/158 (29%), Positives = 53/158 (33%), Gaps = 32/158 (20%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP--PPVQATPHPFPAVTPDLIVQTPVMT 240
            TGT  P  + +  TT  +   TP  TQTP   P       TP P P  T     QTP  T
Sbjct: 3524 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTT 3578

Query: 241  VVPPQPLQTPPPVPPQPQPPP----------APAPQPVQSHPP-------IIAATPQPVK 283
             +      TP P P   Q P            P P P  +  P           TP P  
Sbjct: 3579 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3638

Query: 284  TKKGVKRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
            T          TT TT+ P   P     P+  P   TT
Sbjct: 3639 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3676



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 46/158 (29%), Positives = 53/158 (33%), Gaps = 32/158 (20%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP--PPVQATPHPFPAVTPDLIVQTPVMT 240
            TGT  P  + +  TT  +   TP  TQTP   P       TP P P  T     QTP  T
Sbjct: 3570 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTT 3624

Query: 241  VVPPQPLQTPPPVPPQPQPPP----------APAPQPVQSHPP-------IIAATPQPVK 283
             +      TP P P   Q P            P P P  +  P           TP P  
Sbjct: 3625 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3684

Query: 284  TKKGVKRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
            T          TT TT+ P   P     P+  P   TT
Sbjct: 3685 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3722



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 46/158 (29%), Positives = 53/158 (33%), Gaps = 32/158 (20%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP--PPVQATPHPFPAVTPDLIVQTPVMT 240
            TGT  P  + +  TT  +   TP  TQTP   P       TP P P  T     QTP  T
Sbjct: 3593 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTT 3647

Query: 241  VVPPQPLQTPPPVPPQPQPPP----------APAPQPVQSHPP-------IIAATPQPVK 283
             +      TP P P   Q P            P P P  +  P           TP P  
Sbjct: 3648 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3707

Query: 284  TKKGVKRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
            T          TT TT+ P   P     P+  P   TT
Sbjct: 3708 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3745



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 46/158 (29%), Positives = 53/158 (33%), Gaps = 32/158 (20%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP--PPVQATPHPFPAVTPDLIVQTPVMT 240
            TGT  P  + +  TT  +   TP  TQTP   P       TP P P  T     QTP  T
Sbjct: 3639 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTT 3693

Query: 241  VVPPQPLQTPPPVPPQPQPPP----------APAPQPVQSHPP-------IIAATPQPVK 283
             +      TP P P   Q P            P P P  +  P           TP P  
Sbjct: 3694 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3753

Query: 284  TKKGVKRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
            T          TT TT+ P   P     P+  P   TT
Sbjct: 3754 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3791



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 46/158 (29%), Positives = 53/158 (33%), Gaps = 32/158 (20%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP--PPVQATPHPFPAVTPDLIVQTPVMT 240
            TGT  P  + +  TT  +   TP  TQTP   P       TP P P  T     QTP  T
Sbjct: 3662 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTT 3716

Query: 241  VVPPQPLQTPPPVPPQPQPPP----------APAPQPVQSHPP-------IIAATPQPVK 283
             +      TP P P   Q P            P P P  +  P           TP P  
Sbjct: 3717 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3776

Query: 284  TKKGVKRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
            T          TT TT+ P   P     P+  P   TT
Sbjct: 3777 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3814



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 46/158 (29%), Positives = 53/158 (33%), Gaps = 32/158 (20%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP--PPVQATPHPFPAVTPDLIVQTPVMT 240
            TGT  P  + +  TT  +   TP  TQTP   P       TP P P  T     QTP  T
Sbjct: 3708 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTT 3762

Query: 241  VVPPQPLQTPPPVPPQPQPPP----------APAPQPVQSHPP-------IIAATPQPVK 283
             +      TP P P   Q P            P P P  +  P           TP P  
Sbjct: 3763 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3822

Query: 284  TKKGVKRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
            T          TT TT+ P   P     P+  P   TT
Sbjct: 3823 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3860



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 46/158 (29%), Positives = 53/158 (33%), Gaps = 32/158 (20%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP--PPVQATPHPFPAVTPDLIVQTPVMT 240
            TGT  P  + +  TT  +   TP  TQTP   P       TP P P  T     QTP  T
Sbjct: 3731 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTT 3785

Query: 241  VVPPQPLQTPPPVPPQPQPPP----------APAPQPVQSHPP-------IIAATPQPVK 283
             +      TP P P   Q P            P P P  +  P           TP P  
Sbjct: 3786 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3845

Query: 284  TKKGVKRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
            T          TT TT+ P   P     P+  P   TT
Sbjct: 3846 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3883



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 46/158 (29%), Positives = 53/158 (33%), Gaps = 32/158 (20%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP--PPVQATPHPFPAVTPDLIVQTPVMT 240
            TGT  P  + +  TT  +   TP  TQTP   P       TP P P  T     QTP  T
Sbjct: 3777 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTT 3831

Query: 241  VVPPQPLQTPPPVPPQPQPPP----------APAPQPVQSHPP-------IIAATPQPVK 283
             +      TP P P   Q P            P P P  +  P           TP P  
Sbjct: 3832 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3891

Query: 284  TKKGVKRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
            T          TT TT+ P   P     P+  P   TT
Sbjct: 3892 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3929



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 46/158 (29%), Positives = 53/158 (33%), Gaps = 32/158 (20%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP--PPVQATPHPFPAVTPDLIVQTPVMT 240
            TGT  P  + +  TT  +   TP  TQTP   P       TP P P  T     QTP  T
Sbjct: 3800 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTT 3854

Query: 241  VVPPQPLQTPPPVPPQPQPPP----------APAPQPVQSHPP-------IIAATPQPVK 283
             +      TP P P   Q P            P P P  +  P           TP P  
Sbjct: 3855 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3914

Query: 284  TKKGVKRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
            T          TT TT+ P   P     P+  P   TT
Sbjct: 3915 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3952



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 46/158 (29%), Positives = 53/158 (33%), Gaps = 32/158 (20%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP--PPVQATPHPFPAVTPDLIVQTPVMT 240
            TGT  P  + +  TT  +   TP  TQTP   P       TP P P  T     QTP  T
Sbjct: 3846 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTT 3900

Query: 241  VVPPQPLQTPPPVPPQPQPPP----------APAPQPVQSHPP-------IIAATPQPVK 283
             +      TP P P   Q P            P P P  +  P           TP P  
Sbjct: 3901 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3960

Query: 284  TKKGVKRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
            T          TT TT+ P   P     P+  P   TT
Sbjct: 3961 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3998



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 46/158 (29%), Positives = 53/158 (33%), Gaps = 32/158 (20%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP--PPVQATPHPFPAVTPDLIVQTPVMT 240
            TGT  P  + +  TT  +   TP  TQTP   P       TP P P  T     QTP  T
Sbjct: 3869 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTT 3923

Query: 241  VVPPQPLQTPPPVPPQPQPPP----------APAPQPVQSHPP-------IIAATPQPVK 283
             +      TP P P   Q P            P P P  +  P           TP P  
Sbjct: 3924 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3983

Query: 284  TKKGVKRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
            T          TT TT+ P   P     P+  P   TT
Sbjct: 3984 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 4021



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 46/158 (29%), Positives = 53/158 (33%), Gaps = 32/158 (20%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP--PPVQATPHPFPAVTPDLIVQTPVMT 240
            TGT  P  + +  TT  +   TP  TQTP   P       TP P P  T     QTP  T
Sbjct: 3915 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTT 3969

Query: 241  VVPPQPLQTPPPVPPQPQPPP----------APAPQPVQSHPP-------IIAATPQPVK 283
             +      TP P P   Q P            P P P  +  P           TP P  
Sbjct: 3970 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 4029

Query: 284  TKKGVKRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
            T          TT TT+ P   P     P+  P   TT
Sbjct: 4030 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 4067



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 46/158 (29%), Positives = 53/158 (33%), Gaps = 32/158 (20%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP--PPVQATPHPFPAVTPDLIVQTPVMT 240
            TGT  P  + +  TT  +   TP  TQTP   P       TP P P  T     QTP  T
Sbjct: 3938 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTT 3992

Query: 241  VVPPQPLQTPPPVPPQPQPPP----------APAPQPVQSHPP-------IIAATPQPVK 283
             +      TP P P   Q P            P P P  +  P           TP P  
Sbjct: 3993 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 4052

Query: 284  TKKGVKRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
            T          TT TT+ P   P     P+  P   TT
Sbjct: 4053 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 4090



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 46/158 (29%), Positives = 53/158 (33%), Gaps = 32/158 (20%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP--PPVQATPHPFPAVTPDLIVQTPVMT 240
            TGT  P  + +  TT  +   TP  TQTP   P       TP P P  T     QTP  T
Sbjct: 3984 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTT 4038

Query: 241  VVPPQPLQTPPPVPPQPQPPP----------APAPQPVQSHPP-------IIAATPQPVK 283
             +      TP P P   Q P            P P P  +  P           TP P  
Sbjct: 4039 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 4098

Query: 284  TKKGVKRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
            T          TT TT+ P   P     P+  P   TT
Sbjct: 4099 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 4136



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 46/158 (29%), Positives = 53/158 (33%), Gaps = 32/158 (20%)

Query: 186  TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNP--PPVQATPHPFPAVTPDLIVQTPVMT 240
            TGT  P  + +  TT  +   TP  TQTP   P       TP P P  T     QTP  T
Sbjct: 4007 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTT 4061

Query: 241  VVPPQPLQTPPPVPPQPQPPP----------APAPQPVQSHPP-------IIAATPQPVK 283
             +      TP P P   Q P            P P P  +  P           TP P  
Sbjct: 4062 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 4121

Query: 284  TKKGVKRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
            T          TT TT+ P   P     P+  P   TT
Sbjct: 4122 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 4159



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 42/143 (29%), Positives = 47/143 (32%), Gaps = 19/143 (13%)

Query: 193  VSTVPNTTQASTPPQTQTPQPNP----PPVQATPHPFPAVTPDLIVQTPVMTVVP---PQ 245
            ++T    T   TP  TQTP   P      V  TP P    TP     T   TV P   P 
Sbjct: 1901 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 1960

Query: 246  PLQTPPPVPPQPQPPPAPAPQPVQSHPP-------IIAATPQPVKTKKGVKRKADTTTPT 298
              QTP   P        P P P  +  P           TP P  T          TT T
Sbjct: 1961 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2020

Query: 299  TIDPIHEP-----PSLPPEPKTT 316
            T+ P   P     P+  P   TT
Sbjct: 2021 TVTPTPTPTGTQTPTTTPITTTT 2043



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 40/138 (28%), Positives = 46/138 (33%), Gaps = 15/138 (10%)

Query: 194  STVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVP---PQPLQTP 250
            +T+  TT  +  P T TP      V  TP P    TP     T   TV P   P   QTP
Sbjct: 1883 TTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 1942

Query: 251  PPVPPQPQPPPAPAPQPVQSHPP-------IIAATPQPVKTKKGVKRKADTTTPTTIDPI 303
               P        P P P  +  P           TP P  T          TT TT+ P 
Sbjct: 1943 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2002

Query: 304  HEP-----PSLPPEPKTT 316
              P     P+  P   TT
Sbjct: 2003 PTPTGTQTPTTTPITTTT 2020



 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 39/128 (30%), Positives = 47/128 (36%), Gaps = 15/128 (11%)

Query: 186  TGTAKPGVSTVPNT--TQASTPPQTQTPQ------PNPPPVQATPHPFPAVTPDLIVQT- 236
            T T  P  +T P+   T  +TPP T TP       P+PP    T  P P  TP   + T 
Sbjct: 1654 TTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTT-PSPTTTPSSPITTT 1712

Query: 237  --PVMTVVPPQP---LQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRK 291
              P  T  P  P   + TP P      P       P  +    +  TP P          
Sbjct: 1713 TTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSP 1772

Query: 292  ADTTTPTT 299
              TTTPTT
Sbjct: 1773 FSTTTPTT 1780



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 29/96 (30%), Positives = 37/96 (38%), Gaps = 7/96 (7%)

Query: 186  TGTAKPGVSTVPNT--TQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVP 243
            T    P  +T P++  T  +TP  T TP P PP    TP P    +P     T  MT +P
Sbjct: 1694 TTMTTPSPTTTPSSPITTTTTPSSTTTPSP-PPTTMTTPSPTTTPSP----PTTTMTTLP 1748

Query: 244  PQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATP 279
            P    +P    P P     P   P  +  P     P
Sbjct: 1749 PTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTPCVP 1784



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 29/92 (31%), Positives = 32/92 (34%), Gaps = 8/92 (8%)

Query: 231  DLIVQTPVMTVVPPQPLQT-----PPPVPPQPQPPPAPAPQPVQS-HPPIIAATPQPVKT 284
            D  + TP      P P  T     PP   P P       P P  +  PPI   T  P  T
Sbjct: 1393 DKCITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTT 1452

Query: 285  KKGVKRKADTTTPTTIDPIHEPPSLPPEPKTT 316
                     TT P T  P   PP+  P P TT
Sbjct: 1453 TPSPPISTTTTPPPTTTP--SPPTTTPSPPTT 1482



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 31/117 (26%), Positives = 36/117 (30%), Gaps = 12/117 (10%)

Query: 212  QPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSH 271
            QP       T +P P  T  +   T V     P   QTP   P        P P P  + 
Sbjct: 1881 QPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 1940

Query: 272  PP-------IIAATPQPVKTKKGVKRKADTTTPTTIDPIHEP-----PSLPPEPKTT 316
             P           TP P  T          TT TT+ P   P     P+  P   TT
Sbjct: 1941 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 1997



 Score = 33.9 bits (76), Expect = 0.54
 Identities = 25/98 (25%), Positives = 36/98 (36%), Gaps = 4/98 (4%)

Query: 161  INELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQA 220
            I   P+  T  M   +         T T  P  +T P+    +    + T  P+PP    
Sbjct: 1685 ITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTM 1744

Query: 221  TPHPFPAVTPDLIVQTPV-MTVVPP--QPLQTPPPVPP 255
            T  P P  T   +  TP+  ++ PP   P  T  P  P
Sbjct: 1745 TTLP-PTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTP 1781



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 23/99 (23%), Positives = 33/99 (33%), Gaps = 3/99 (3%)

Query: 246  PLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHE 305
            P+      P  P   P+P P    + PP    TP P  T         T +P        
Sbjct: 1391 PMDKCITTPSPPTTTPSPPPTSTTTLPP--TTTPSPPTTTTTTPPPTTTPSPPITTTTTP 1448

Query: 306  PPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAP 344
            PP+  P P  +       ++ P  P     P +   P+P
Sbjct: 1449 PPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTT-PSP 1486


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 71.2 bits (173), Expect = 3e-12
 Identities = 114/527 (21%), Positives = 193/527 (36%), Gaps = 93/527 (17%)

Query: 206   PQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQP------QP 259
             P+ + P P P   +  P   P V    + +  V   +PP+P   PP VP  P      + 
Sbjct: 10534 PEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKK 10593

Query: 260   PPAPAPQPVQSHPPIIAATPQPVKTKKGV---KRKADTTTPTTIDPIHE--------PPS 308
              PA  P+  +  P  +   P+ V  +K V     K     PT +  + +        P +
Sbjct: 10594 VPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEA 10653

Query: 309   LPPEPKT---------------TKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQ 353
             +PP+P++                   +  E   P  PP+  VP  +  P PEK +     
Sbjct: 10654 IPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKK--PVPEKKAPA--- 10708

Query: 354   LKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYR 413
                       + AKK      P   PV V  +      +++        +  K EA   +
Sbjct: 10709 ----------VVAKK------PELPPVKVPEVPK----EVVPEKKVPLVVPKKPEAPPAK 10748

Query: 414   DAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAV 473
                E   +V            P+ +V    +      E+  AK+P+ P++PV+    PAV
Sbjct: 10749 -VPEVPKEV-----------VPEKKVAVPKKP-----EVPPAKVPEVPKKPVLE-EKPAV 10790

Query: 474   PPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQ 533
             P P +  +PP       +  +  +      EEE+   +AE +E         A   +P++
Sbjct: 10791 PVPERAESPPPEVYEEPEEIAPEEEIA--PEEEKPVPVAEEEE---PEVPPPAVPEEPKK 10845

Query: 534   NKPKKKEK--DKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPM 591
               P+KK     K E    K    E+V E  K K + PPP            + + +  P 
Sbjct: 10846 IIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIP- 10904

Query: 592   KSKPPPTYESEEEDKCKPMSYE--EKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNP 649
             K K P   +  E+ +  P+     EK+   L   + P  K   V+  +  + P  +    
Sbjct: 10905 KKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKV 10964

Query: 650   DEIEIDF-------ETLKPSTLRELERYVTSCLRKKRKPQAEKVDVI 689
             +  +++        E   P  + E+E   T   R+++ P+  KV  I
Sbjct: 10965 EPKKLEKVKKPAVPEPPPPKPVEEVE-VPTVTKRERKIPEPTKVPEI 11010



 Score = 63.9 bits (154), Expect = 5e-10
 Identities = 101/426 (23%), Positives = 158/426 (37%), Gaps = 65/426 (15%)

Query: 205  PPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPA 264
            PP+       P P +  P P P       V+ P     P  P     PVP + +P P P 
Sbjct: 9285 PPKVPELPEKPAPEEVAPVPIPKK-----VEPPA----PKVPEVPKKPVPEEKKPVPVPK 9335

Query: 265  PQPVQSHPPIIAATP-QPVKTKK---GVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQ 320
             +P  + PP +   P +PV  +K    V +K +   P  +  + +   +  E K T + Q
Sbjct: 9336 KEP--AAPPKVPEVPKKPVPEEKIPVPVAKKKE-APPAKVPEVQK--GVVTEEKITIVTQ 9390

Query: 321  RRESSRPVKP--PKKDVPDSQQHPAPEKSSKVSEQLKCCSGILKEMFAKKHAAYAWPFYK 378
            R ES  P  P  PKK VP+ ++ P P K  +V    K    + K+   ++  A   P  K
Sbjct: 9391 REESPPPAVPEIPKKKVPE-ERKPVPRKEEEVPPPPK-VPALPKKPVPEEKVAVPVPVAK 9448

Query: 379  PVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHE 438
                            K P   + +  K    E R    F A+ +L F+   +     HE
Sbjct: 9449 ----------------KAPPPRAEVSKKTVVEEKR----FVAEEKLSFAVPQRVEVTRHE 9488

Query: 439  VVA-----MARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSS 493
            V A      + + + V    + +   E EE         +  P + V        S    
Sbjct: 9489 VSAEEEWSYSEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVE 9548

Query: 494  SDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNK---PKKK------EKDKK 544
            ++    T     ER ++   L+ ++ A  E+      P+  K   P+KK      +K+K 
Sbjct: 9549 AEPAEVT-----ERQEKKIVLKPKIPAKIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKV 9603

Query: 545  EKKKEKHKRKEEVEENKKS----KAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYE 600
               K   + K+ V E K      K +EP P K  + +   +   K   A  K + PP   
Sbjct: 9604 PPPKVPEEPKKPVPEKKVPPKVIKMEEPLPAKVTERHMQITQEEKVLVAVTKKEAPPKAR 9663

Query: 601  SEEEDK 606
              EE K
Sbjct: 9664 VPEEPK 9669



 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 92/448 (20%), Positives = 151/448 (33%), Gaps = 104/448 (23%)

Query: 189  AKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQ 248
            A+P   T     +    P+       PPP +    P   + P+  V  PV     P+  +
Sbjct: 9549 AEPAEVTERQEKKIVLKPKIPAKIEEPPPAKVPEAP-KKIVPEKKVPAPV-----PKKEK 9602

Query: 249  TPPPVPPQPQPPPAPA----PQPVQSHPPIIAATP----QPVKTKKGVKRKADTTTPTTI 300
             PPP  P+    P P     P+ ++   P+ A       Q  + +K +        P   
Sbjct: 9603 VPPPKVPEEPKKPVPEKKVPPKVIKMEEPLPAKVTERHMQITQEEKVLVAVTKKEAPPKA 9662

Query: 301  DPIHEPPSLPPEPKTTKLGQRRESSRP----------VKPPKKDVPDSQQHPAPEKSSKV 350
                EP    PE K  KL  +RE   P          VK  K  +   ++ P P K   +
Sbjct: 9663 RVPEEPKRAVPEEKVLKLKPKREEEPPAKVTEFRKRVVKEEKVSIEAPKREPQPIKEVTI 9722

Query: 351  SEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKH-PMDMSTIKSKLEA 409
             E+ +    + +E         A    +  + E    +DY +  ++ P +      + E 
Sbjct: 9723 MEEKERAYTLEEE---------AVSVQREEEYEEYEEYDYKEFEEYEPTEEYDQYEEYEE 9773

Query: 410  REYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVS 469
            REY   +E                   HE                 +   EPE+P+    
Sbjct: 9774 REYERYEE-------------------HE-----------------EYITEPEKPIPVKP 9797

Query: 470  SPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALS 529
             P  P PTK  APP+                              +   KAV E+   + 
Sbjct: 9798 VPEEPVPTKPKAPPA------------------------------KVLKKAVPEEKVPVP 9827

Query: 530  QPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPA 589
             P++ KP   +  ++ KK  + K +  + + +K +  EP  K   K         +K P 
Sbjct: 9828 IPKKLKPPPPKVPEEPKKVFEEKIRISITKREKEQVTEPAAKVPMK--PKRVVAEEKVPV 9885

Query: 590  PMKSKPPPTYESEEEDKCKP--MSYEEK 615
            P K   PP    E   + +P  +++EE+
Sbjct: 9886 PRKEVAPPVRVPEVPKELEPEEVAFEEE 9913



 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 117/576 (20%), Positives = 210/576 (36%), Gaps = 100/576 (17%)

Query: 45    PPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQ-PVDAVKL----NLPDYYK 99
             PPPP+   P +PK+   +    +R+ +    K Q   P  + P+   ++     +P   K
Sbjct: 9834  PPPPKV--PEEPKKVFEEK---IRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRK 9888

Query: 100   IIKTPMDMGTIKKRLENNYYWNAQECI---QDFNTMFTNCYIYNKPGDDIVLMAEALEKL 156
              +  P+ +  + K LE       +E +   +++       YI+    ++  +  E +  +
Sbjct: 9889  EVAPPVRVPEVPKELEPEEVAFEEEVVTHVEEYLVEEEEEYIHE---EEEFITEEEVVPV 9945

Query: 157   FLQKINELPT----EETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQ 212
                K+ E+P     EE + + V  K      KE   AK  V  VP   +   P     P+
Sbjct: 9946  IPVKVPEVPRKPVPEEKKPVPVPKK------KEAPPAK--VPEVPKKPEEKVP--VLIPK 9995

Query: 213   PNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPP-VPPQPQPP------PAPAP 265
                PP    P       P+  V  PV     P+ ++ PP  VP  P+ P      P PAP
Sbjct: 9996  KEKPPPAKVPEVPKKPVPEEKVPVPV-----PKKVEAPPAKVPEVPKKPVPEKKVPVPAP 10050

Query: 266   QPVQSHPPIIAATPQPV----KTKKGVKRKADT---TTPTTIDPIHEPPSLPPEPKTTKL 318
             + V++ P  +   P+ +    K    V +K +      P   +P+  P +LP E +    
Sbjct: 10051 KKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVL-F 10109

Query: 319   GQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQLKCCSGILKEMFAKKHAAYAWPFYK 378
              +       V P +++V   ++   PE+   + E+        +E+  ++        Y 
Sbjct: 10110 EEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEE--------EEIPPEEEEVPPEEEYV 10161

Query: 379   PVDVEALGLHDYCDIIKH----PMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNP 434
             P + E +   +    +K     P  +  IK K+  ++                       
Sbjct: 10162 PEEEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKK----------------------- 10198

Query: 435   PDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSS 494
                    +  K ++    +  ++P + EE  + +       P +V   P     S +   
Sbjct: 10199 ------VVIPKKEEAPPAKVPEVPKKVEEKRIILPKEEEVLPVEVTEEPEEEPISEEEIP 10252

Query: 495   DSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRK 554
             +   S ++ EE    R+ E+ +  KAV E    +       PKK E    +  K+  + K
Sbjct: 10253 EEPPSIEEVEEVAPPRVPEVIK--KAVPEAPTPV-------PKKVEAPPAKVSKKIPEEK 10303

Query: 555   EEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAP 590
               V   KK       P+  KK       V KKE  P
Sbjct: 10304 VPVPVQKKEAPPAKVPEVPKKVPEKKVLVPKKEAVP 10339



 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 94/422 (22%), Positives = 154/422 (36%), Gaps = 57/422 (13%)

Query: 226  PAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVK-T 284
            P   PD  V  P M +    P + PP V P   P P   P P +  PP     P+ ++ T
Sbjct: 8934 PPDIPDSRVPIPTMPIRAVPPEEIPPVVAP---PIPLLLPTPEEKKPP-----PKRIEVT 8985

Query: 285  KKGVKRKAD--TTTPTTIDPIHEPPSLPPEPKT---------TKLGQRRESSRPVKPPKK 333
            KK VK+ A      P  + P  E    PP P T           +  + E  + +   +K
Sbjct: 8986 KKAVKKDAKKVVAKPKEMTPREEIVKKPPPPTTLIPAKAPEIIDVSSKAEEVKIMTITRK 9045

Query: 334  DVPDSQQHPAPEKSSKVSEQLKCCSGILKEMFAKKHA-AYAWPFYKPVDVEALGLHDYCD 392
                 ++    EK   V ++ +      +E + +     Y  PF +P   E     DY +
Sbjct: 9046 KEVQKEKEAVYEKKQAVHKEKRVFIESFEEPYDELEVEPYTEPFEQPYYEEP--DEDYEE 9103

Query: 393  I---IKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDV 449
            I    K  +     +   E +EY + +E   +    +   Y+    + EV+ + +++ + 
Sbjct: 9104 IKVEAKKEVHEEWEEDFEEGQEYYEREEGYDEGEEEWEEAYQ----EREVIQVQKEVYE- 9158

Query: 450  FEMRFAKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSE-EERA 508
             E    K+P         V     PPP KV+  P        S    +     ++  E +
Sbjct: 9159 -ESHERKVP-------AKVPEKKAPPPPKVIKKPVIEKIEKTSRRMEEEKVQVTKVPEVS 9210

Query: 509  QRLAELQEQLKAVHEQLAALSQPQQNKPK---KKEK-------DKKEKKKEKHKRKEEVE 558
            +++   +     V E++  +  P  +  K    +EK       +++        +KE V 
Sbjct: 9211 KKIVPQKPSRTPVQEEVIEVKVPAVHTKKMVISEEKMFFASHTEEEVSVTVPEVQKEIVT 9270

Query: 559  ENK----KSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEE 614
            E K     SK  EPPPK  +             P P K +PP     E   K  P   EE
Sbjct: 9271 EEKIHVAISKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVP---EE 9327

Query: 615  KR 616
            K+
Sbjct: 9328 KK 9329



 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 95/483 (19%), Positives = 165/483 (34%), Gaps = 91/483 (18%)

Query: 206   PQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAP 265
             P+ + P P P  V+A P   P V   LI +    T VP +    PP VP + +P P P  
Sbjct: 10041 PEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVA 10100

Query: 266   QPVQSH---PPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQR- 321
              P +        I    + +  ++ V  + +   P   + + E   +PPE +     +  
Sbjct: 10101 LPQEEEVLFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEY 10160

Query: 322   ---------RESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQLKCCSGILKEMFAKKHAAY 372
                       E   P   PK  VP     P PE   KV+E+        K +  KK  A 
Sbjct: 10161 VPEEEEFVPEEEVLPEVKPKVPVP----APVPEIKKKVTEK--------KVVIPKKEEA- 10207

Query: 373   AWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREY---RDAQEFGADVRLMFSNC 429
                                     P  +  +  K+E +     ++ +    +V       
Sbjct: 10208 -----------------------PPAKVPEVPKKVEEKRIILPKEEEVLPVEVT------ 10238

Query: 430   YKYNPPDHEVVA---MARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSS 486
                  P+ E ++   +  +   + E+     P  PE    AV     P P KV APP+  
Sbjct: 10239 ---EEPEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPEAPTPVPKKVEAPPAKV 10295

Query: 487   DSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEK 546
                  S    +       +++    A++ E  K V E+   + + +   P K     +EK
Sbjct: 10296 -----SKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLVPKKEAVPPAKGRTVLEEK 10350

Query: 547   KKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDK 606
                  +++  V+E  + +  E   ++  +    +      E           +E EE  K
Sbjct: 10351 VSVAFRQEVVVKERLELEVVEAEVEEIPEEEEFHEVEEYFEEGEF-------HEVEEFIK 10403

Query: 607   CKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSRE------PSLKNSNPDEIEIDFETLK 660
              +    EE+ ++         EK+ RV+ + ++ E      P      P+  E      K
Sbjct: 10404 LEQHRVEEEHRV---------EKVHRVIEVFEAEEVEVFEKPKAPPKGPEISEKIIPPKK 10454

Query: 661   PST 663
             P T
Sbjct: 10455 PPT 10457



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 97/503 (19%), Positives = 186/503 (36%), Gaps = 99/503 (19%)

Query: 142   PGDDIVLMAEAL--EKLFLQKINELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNT 199
             P ++ VL  E +  E+  L +  E+  EE E++            E     P    +P  
Sbjct: 10102 PQEEEVLFEEEIVPEEEVLPEEEEVLPEEEEVL-----------PEEEEVLPEEEEIPPE 10150

Query: 200   TQASTPPQTQTPQPNP--PPVQATPH-----PFPAVTPDLIVQTPVMTVVPPQPLQTP-- 250
              +   P +   P+     P  +  P      P PA  P++  +     VV P+  + P  
Sbjct: 10151 EEEVPPEEEYVPEEEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPA 10210

Query: 251   --PPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHE--P 306
               P VP + +      P+  +  P  +   P+    ++ +  +     P +I+ + E  P
Sbjct: 10211 KVPEVPKKVEEKRIILPKEEEVLPVEVTEEPE----EEPISEEEIPEEPPSIEEVEEVAP 10266

Query: 307   PSLP------------PEPKTTKLGQRRESSR------PVKPPKKDVPDSQQHPAPEKSS 348
             P +P            P PK  +    + S +      PV   KK+ P ++    PE   
Sbjct: 10267 PRVPEVIKKAVPEAPTPVPKKVEAPPAKVSKKIPEEKVPVPVQKKEAPPAK---VPEVPK 10323

Query: 349   KVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKL- 407
             KV E+        K +  KK A         ++ +         ++K  +++  +++++ 
Sbjct: 10324 KVPEK--------KVLVPKKEAVPPAKGRTVLEEKVSVAFRQEVVVKERLELEVVEAEVE 10375

Query: 408   ---EAREYRDAQEFGADVRL----MFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDE 460
                E  E+ + +E+  +        F    ++   +   V    ++ +VFE    ++ ++
Sbjct: 10376 EIPEEEEFHEVEEYFEEGEFHEVEEFIKLEQHRVEEEHRVEKVHRVIEVFEAEEVEVFEK 10435

Query: 461   PEEPVVA--VSSPAVP---PPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQ 515
             P+ P     +S   +P   PPTKVV                        +E   ++ E+ 
Sbjct: 10436 PKAPPKGPEISEKIIPPKKPPTKVV----------------------PRKEPPAKVPEVP 10473

Query: 516   EQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKK 575
             +++  V E++    +P+   P  K  +    K+   ++K  V   KK +A  PPPK  + 
Sbjct: 10474 KKI-VVEEKVRVPEEPR--VPPTKVPEVLPPKEVVPEKKVPVPPAKKPEA--PPPKVPEA 10528

Query: 576   NNSSNSNVSKKEPAPMKSKPPPT 598
                         P P K + PPT
Sbjct: 10529 PKEVVPEKKVPVPPPKKPEVPPT 10551



 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 39/158 (24%), Positives = 64/158 (40%), Gaps = 16/158 (10%)

Query: 197   PNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQ--PLQTPPPVP 254
             P  ++   PP+   P     P +  P   P V   ++V+  V     P+  P + P  +P
Sbjct: 10443 PEISEKIIPPKK--PPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLP 10500

Query: 255   PQPQPP----PAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLP 310
             P+   P    P P  +  ++ PP +   P+ V  +K V        P    P   P  +P
Sbjct: 10501 PKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVPEKKVP------VPPPKKPEVPPTKVP 10554

Query: 311   PEPKTTKLGQRRESSRPVKP--PKKDVPDSQQHPAPEK 346
               PK     ++   + P KP  P  +VP++ +   PEK
Sbjct: 10555 EVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEK 10592



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 86/409 (21%), Positives = 149/409 (36%), Gaps = 89/409 (21%)

Query: 242   VPPQPLQTPPPVPPQP--------QPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKAD 293
             VP +P+ T P  PP          +  P P P+ ++  PP +   P+ V  +K       
Sbjct: 9798  VPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKPPPPKVPEEPKKVFEEK----IRI 9853

Query: 294   TTTPTTIDPIHEPPS-LPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVSE 352
             + T    + + EP + +P +PK     ++    R    P   VP+  +   PE+ +   E
Sbjct: 9854  SITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKELEPEEVAFEEE 9913

Query: 353   QLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREY 412
              +      L                  V+ E   +H+  + I     +  I  K+     
Sbjct: 9914  VVTHVEEYL------------------VEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPR 9955

Query: 413   RDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRF--------AKMPDEPEEP 464
             +   E    V +      K   P  +V  + +K ++   +          AK+P+ P++P
Sbjct: 9956  KPVPEEKKPVPVP----KKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKP 10011

Query: 465   VVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQ 524
             V     P VP P KV APP+                         ++ E+ +  K V E+
Sbjct: 10012 VPEEKVP-VPVPKKVEAPPA-------------------------KVPEVPK--KPVPEK 10043

Query: 525   LAALSQPQQ-NKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNV 583
                +  P++   P  K  +  +K   + K+   V +    K + PPPK  KK        
Sbjct: 10044 KVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPK----KVEAPPPKVPKK-------- 10091

Query: 584   SKKEPAPMKSKPPPTYESEEEDKCKP---MSYEEKRQLSLDINKLPGEK 629
               +EP P+    P   E   E++  P   +  EE+  L  +   LP E+
Sbjct: 10092 --REPVPVPVALPQEEEVLFEEEIVPEEEVLPEEEEVLPEEEEVLPEEE 10138



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 45/187 (24%), Positives = 66/187 (35%), Gaps = 23/187 (12%)

Query: 154   EKLFLQKINELPTEETEIMIVQAKGRGRGRKETGTAKPG-VSTVPNTTQASTPPQTQTPQ 212
             EK   + + E   E  E +++++  R R  +E    +P  +  V        PP     +
Sbjct: 10929 EKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEE 10988

Query: 213   PNPPPV----QATPHP--FPAVTPDLIVQTPVMTVVPPQPLQT--PPPVPPQPQPPPAPA 264
                P V    +  P P   P + P + +  P     P   ++T  PPPV P+P P  AP 
Sbjct: 10989 VEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPV 11048

Query: 265   PQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRES 324
               PV        A  +     KG              PI   P   P P   +  + R  
Sbjct: 11049 TVPVVGKKAEAKAPKEEAAKPKG--------------PIKGVPKKTPSPIEAERRKLRPG 11094

Query: 325   SRPVKPP 331
             S   KPP
Sbjct: 11095 SGGEKPP 11101



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 95/426 (22%), Positives = 149/426 (34%), Gaps = 74/426 (17%)

Query: 231   DLIVQTPVMTVVPPQPLQTP-PPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVK 289
             + I +  V+ V+P +  + P  PVP + +P P P  +     PP  A  P+       V 
Sbjct: 9935  EFITEEEVVPVIPVKVPEVPRKPVPEEKKPVPVPKKKEA---PP--AKVPE-------VP 9982

Query: 290   RKADTTTPTTIDPIHEPP--SLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKS 347
             +K +   P  I    +PP   +P  PK           +PV   K  VP  ++  AP   
Sbjct: 9983  KKPEEKVPVLIPKKEKPPPAKVPEVPK-----------KPVPEEKVPVPVPKKVEAPP-- 10029

Query: 348   SKVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKL 407
             +KV E  K      K +  KK      P   P  VEA            P  +  +  KL
Sbjct: 10030 AKVPEVPK------KPVPEKKV-----PVPAPKKVEA-----------PPAKVPEVPKKL 10067

Query: 408   EAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVA 467
                E +        V        K   P    VA+ ++ + +FE         PEE V+ 
Sbjct: 10068 IPEEKKPTP-VPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIV-----PEEEVLP 10121

Query: 468   VSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAA 527
                  +P   +V+ P        +     +      EEE      E   + + + E    
Sbjct: 10122 EEEEVLPEEEEVL-PEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPEEEVLPEVKPK 10180

Query: 528   LSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKE 587
             +  P    P  + K K  +KK    +KEE    K  +     PKK ++         +  
Sbjct: 10181 VPVPA---PVPEIKKKVTEKKVVIPKKEEAPPAKVPEV----PKKVEEKRIILPKEEEVL 10233

Query: 588   PAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNS 647
             P  +  +P     SEEE   +P S EE  +++            RV  +I+   P     
Sbjct: 10234 PVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPP----------RVPEVIKKAVPEAPTP 10283

Query: 648   NPDEIE 653
              P ++E
Sbjct: 10284 VPKKVE 10289



 Score = 40.0 bits (92), Expect = 0.008
 Identities = 83/405 (20%), Positives = 139/405 (34%), Gaps = 98/405 (24%)

Query: 226  PAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPP----APAPQPVQSHPPIIAATPQP 281
            P V  +++ +  +   +  + ++ PP VP  P+ P     AP P P +  PP       P
Sbjct: 9262 PEVQKEIVTEEKIHVAISKR-VEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVP 9320

Query: 282  VKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQH 341
             K                  P+ E     P PK            P  PPK  VP+  + 
Sbjct: 9321 KK------------------PVPEEKKPVPVPK----------KEPAAPPK--VPEVPKK 9350

Query: 342  PAPEKSSKVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKH----- 396
            P PE+   V               AKK  A   P   P   + +   +   I+       
Sbjct: 9351 PVPEEKIPVP-------------VAKKKEAP--PAKVPEVQKGVVTEEKITIVTQREESP 9395

Query: 397  PMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAK 456
            P  +  I  K    E +       +V           PP  +V A+ +K           
Sbjct: 9396 PPAVPEIPKKKVPEERKPVPRKEEEV-----------PPPPKVPALPKK----------- 9433

Query: 457  MPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERA--QRLAEL 514
                PEE V      AVP P    APP  ++ S  +  +      + +   A  QR+   
Sbjct: 9434 --PVPEEKV------AVPVPVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVT 9485

Query: 515  QEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKK----------SK 564
            + ++ A  E   +  +   +    +E++++E+++ +    E +EE ++          SK
Sbjct: 9486 RHEVSAEEEWSYSEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISK 9545

Query: 565  AKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKP 609
              E  P +  +       +  K PA ++ +PPP    E   K  P
Sbjct: 9546 RVEAEPAEVTERQEKKIVLKPKIPAKIE-EPPPAKVPEAPKKIVP 9589



 Score = 39.3 bits (90), Expect = 0.013
 Identities = 41/148 (27%), Positives = 54/148 (36%), Gaps = 35/148 (23%)

Query: 213   PNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHP 272
             P  PP +  P   P   P  + + P   VV     +    VP +P+ PP   P+ +   P
Sbjct: 10452 PKKPPTKVVPRKEP---PAKVPEVPKKIVV-----EEKVRVPEEPRVPPTKVPEVL---P 10500

Query: 273   PIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPK 332
             P            K V  +     P    P   PP +P  PK        E   PV PPK
Sbjct: 10501 P------------KEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVV----PEKKVPVPPPK 10544

Query: 333   K------DVPDSQQHPAPEKSSKVSEQL 354
             K       VP+  +   PEK  KV E +
Sbjct: 10545 KPEVPPTKVPEVPKAAVPEK--KVPEAI 10570



 Score = 37.4 bits (85), Expect = 0.049
 Identities = 39/182 (21%), Positives = 72/182 (39%), Gaps = 21/182 (11%)

Query: 139 YNKPGDDIVLMAEALEKLFLQKINELPTEETEIMIVQAK------GRGRGRKETGTAKPG 192
           Y+    + V  A +  +L +Q   E+P ++T+ ++  A+       R   + E       
Sbjct: 174 YSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVSTAQISESRQTRIEKKIEAHFDARS 233

Query: 193 VSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQ-TPP 251
           ++TV      +   Q   P   PP +   P       P +  +  +     P P++ +P 
Sbjct: 234 IATVEMVIDGAAGQQL--PHKTPPRIPPKPKSRSPTPPSIAAKAQLARQQSPSPIRHSPS 291

Query: 252 PVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKG--VKRKADTTTPTTIDPIHEPPSL 309
           PV    +   AP P PV+S  P    +  P+++ +   + RK   +T  T       P +
Sbjct: 292 PV----RHVRAPTPSPVRSVSPAARISTSPIRSVRSPLLMRKTQASTVAT------GPEV 341

Query: 310 PP 311
           PP
Sbjct: 342 PP 343



 Score = 36.6 bits (83), Expect = 0.084
 Identities = 43/184 (23%), Positives = 70/184 (38%), Gaps = 29/184 (15%)

Query: 196   VPNTTQASTPPQTQTPQPNP----PPVQATPHPFPAVTPDLIVQTPV--MTVVPPQPLQT 249
             VP   +   PP  + P+P      P ++  P P P   P   V+  +  +  +P + +  
Sbjct: 10852 VPVIKKPEAPPPKE-PEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPE 10910

Query: 250   PPPVPPQPQPPPAPAP---QPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDP---- 302
              P VP + +  P   P   + V+   P     P+     K V RK        ++P    
Sbjct: 10911 KPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLE 10970

Query: 303   ------IHEPPSLPPEPKT-----TKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVS 351
                   + EPP  PP+P       T   + R+   P K P  ++  +   PAPE   K  
Sbjct: 10971 KVKKPAVPEPP--PPKPVEEVEVPTVTKRERKIPEPTKVP--EIKPAIPLPAPEPKPKPE 11026

Query: 352   EQLK 355
              ++K
Sbjct: 11027 AEVK 11030


>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
           sapiens]
          Length = 483

 Score = 70.1 bits (170), Expect = 7e-12
 Identities = 53/167 (31%), Positives = 71/167 (42%), Gaps = 34/167 (20%)

Query: 191 PGVSTVPNTTQASTPPQTQTPQPN--PPPVQATPHPFPAVTPDLIVQTPVMT--VVPPQP 246
           P    + NT++A    +T  P+PN   PP    P P P + P L   +P+ T  V PP P
Sbjct: 147 PASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGP 206

Query: 247 LQ------TPPPVP---PQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTP 297
           L         PPVP   P P PPP P P P+   PP    + + VK +            
Sbjct: 207 LTKGNLPVVAPPVPCAPPPPPPPPPPTPPPL---PPASVLSDKAVKPQ------------ 251

Query: 298 TTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAP 344
             + P+H PP  PP P     G     + P  P +    D+Q+ PAP
Sbjct: 252 --LAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQ----DAQEPPAP 292



 Score = 43.1 bits (100), Expect = 9e-04
 Identities = 52/220 (23%), Positives = 73/220 (33%), Gaps = 62/220 (28%)

Query: 191 PGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFP--------AVTPDLIVQ-----TP 237
           PG  T  N    + PP    P P PPP   TP P P        AV P L         P
Sbjct: 204 PGPLTKGNLPVVA-PPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPP 262

Query: 238 VMTVVPP--------------QPLQTPP------------------PVPPQP-------Q 258
            + ++PP              Q  Q PP                  P PP P        
Sbjct: 263 PLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSET 322

Query: 259 PPPAPAPQPVQSHPP------IIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPE 312
           PPP P   P    PP       + A P P  ++  +++K           ++ PP+ P  
Sbjct: 323 PPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPAR 382

Query: 313 PKTTKLGQRRESS---RPVKPPKKDVPDSQQHPAPEKSSK 349
             TT+L  + + +    P + P   + +   H   +  SK
Sbjct: 383 SPTTELSSKSQQATAWTPTQQPGGQLRNGSLHIIDDFESK 422



 Score = 36.6 bits (83), Expect = 0.084
 Identities = 21/55 (38%), Positives = 22/55 (40%), Gaps = 13/55 (23%)

Query: 239 MTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKAD 293
           M V PP P   PPP PP   PPP P   P             PV T     R+AD
Sbjct: 1   MPVPPPPPPPLPPPPPPLGAPPPPPPSAP-------------PVSTDTSSLRRAD 42



 Score = 32.7 bits (73), Expect = 1.2
 Identities = 27/88 (30%), Positives = 40/88 (45%), Gaps = 8/88 (9%)

Query: 457 MPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQE 516
           MP  P  P      P  PPP  + APP    S+   S+D+ S      + R+  LA++Q+
Sbjct: 1   MPVPPPPP-----PPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQ 55

Query: 517 --QLKAVHEQLAALSQPQQNKPKKKEKD 542
             +L+ V  Q+   S PQ    K   K+
Sbjct: 56  GTRLRKV-TQINDRSAPQIESSKGTNKE 82


>gi|237649104 bromodomain containing 9 isoform 1 [Homo sapiens]
          Length = 597

 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 63/193 (32%), Positives = 89/193 (46%), Gaps = 18/193 (9%)

Query: 330 PPKKDVPDSQQHPAPEKSSKVSEQLKCCSGILKEMFAKK-HAAYAWPFYKPVDVEALGLH 388
           PP + V   +  PA  +S+ + + L+     L+++  K  H  +A+P     D  A G  
Sbjct: 121 PPDRPVRACRTQPAENESTPIQQLLE---HFLRQLQRKDPHGFFAFPV---TDAIAPG-- 172

Query: 389 DYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARK-LQ 447
            Y  IIKHPMD  T+K K+ A EY+   EF AD +LM  N   YN PD     +A+K L 
Sbjct: 173 -YSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILH 231

Query: 448 DVFEM---RFAKMPDEP---EEPVVAVSSPAVPPPTKVVAPPSSSDSSS-DSSSDSDSST 500
             F+M   + A + +E    EEPV  V    V    K   P     S   +   ++ S T
Sbjct: 232 AGFKMMSKQAALLGNEDTAVEEPVPEVVPVQVETAKKSKKPSREVISCMFEPEGNACSLT 291

Query: 501 DDSEEERAQRLAE 513
           D + EE    L E
Sbjct: 292 DSTAEEHVLALVE 304



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 50/179 (27%), Positives = 77/179 (43%), Gaps = 22/179 (12%)

Query: 37  PANAASTNPPP--PETSNPNKP-KRQTNQLQYLLRVVLKTLWKHQFAWPFQQPV-DAVKL 92
           P       PPP  P  +   +P + ++  +Q LL   L+ L +      F  PV DA+  
Sbjct: 112 PGKKVEVEPPPDRPVRACRTQPAENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIA- 170

Query: 93  NLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEA 152
             P Y  IIK PMD GT+K ++  N Y +  E   DF  M  N   YN+P  D V     
Sbjct: 171 --PGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRP--DTVYY--K 224

Query: 153 LEKLFLQKINELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTP 211
           L K  L    ++ +++  ++         G ++T   +P    VP   Q  T  +++ P
Sbjct: 225 LAKKILHAGFKMMSKQAALL---------GNEDTAVEEPVPEVVP--VQVETAKKSKKP 272



 Score = 38.9 bits (89), Expect = 0.017
 Identities = 31/122 (25%), Positives = 58/122 (47%), Gaps = 10/122 (8%)

Query: 476 PTKVVAPPSSSDSSSDSSSDSDSST-DDSEEERAQRLAELQEQLKAVHEQLAALSQPQQN 534
           P K+V     S+ +  S S  DSS  DD  +   +R  E +++ K   E+   L   ++ 
Sbjct: 27  PLKLVLKVGGSEVTELSGSGHDSSYYDDRSDHERERHKEKKKKKKKKSEKEKHLDDEERR 86

Query: 535 KPKKKEKDKKEKKK-EKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKS 593
           K K+++K K+E++  +     ++ +  KK +  EPPP +  +         + +PA  +S
Sbjct: 87  KRKEEKKRKREREHCDTEGEADDFDPGKKVEV-EPPPDRPVR-------ACRTQPAENES 138

Query: 594 KP 595
            P
Sbjct: 139 TP 140



 Score = 33.5 bits (75), Expect = 0.71
 Identities = 20/87 (22%), Positives = 43/87 (49%), Gaps = 2/87 (2%)

Query: 512 AELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPK 571
           +E+ E   + H+      +    + + KEK KK+KKK+  K K   +E ++ + +E   K
Sbjct: 37  SEVTELSGSGHDSSYYDDRSDHERERHKEK-KKKKKKKSEKEKHLDDEERRKRKEEKKRK 95

Query: 572 KTKKNNSSNSNVSKKEPA-PMKSKPPP 597
           + +++  +       +P   ++ +PPP
Sbjct: 96  REREHCDTEGEADDFDPGKKVEVEPPP 122


>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
           sapiens]
          Length = 699

 Score = 68.6 bits (166), Expect = 2e-11
 Identities = 65/267 (24%), Positives = 111/267 (41%), Gaps = 19/267 (7%)

Query: 460 EPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSD---SSTDDSEEERAQRLAEL-- 514
           +P+   V V +    PP    A P  ++  + SSS S    SS+DDSEEE+A    +   
Sbjct: 184 KPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTV 243

Query: 515 -QEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKT 573
            ++Q+ A     AA +  +++   +     +E++++K  + +    +       PPPKK+
Sbjct: 244 PKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKS 303

Query: 574 KKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRV 633
                    V K++P           +S  E++ KP +   K  +S    K P  K    
Sbjct: 304 LGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPT---KAVVSKATTKPPPAK---- 356

Query: 634 VHIIQSREPSLKNSNPDEIEIDFETLKP--STLRELERYVTSCLRKKRKPQAEKVDVIAG 691
               ++ E S  +S+ D  E D    KP  +T     +   +      KP A     + G
Sbjct: 357 ----KAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGG 412

Query: 692 SSKMKGFSSSESESSSESSSSDSEDSE 718
             K+    +  S S  ESSSS+ E ++
Sbjct: 413 GQKLLTRKADSSSSEEESSSSEEEKTK 439



 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 108/558 (19%), Positives = 186/558 (33%), Gaps = 99/558 (17%)

Query: 197 PNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVP-- 254
           P   ++S      + +  PP  Q      P +TP   V     T  PP+P +  P +   
Sbjct: 161 PKKAKSSDSDSDSSSEDEPPKNQK-----PKITP---VTVKAQTKAPPKPARAAPKIANG 212

Query: 255 --PQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPE 312
                    + +     S     AATP+    KK V  KA     TT      P      
Sbjct: 213 KAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATT------PTRKSSS 266

Query: 313 PKTTKLGQRRESSRPVKP---PKKDVPDSQQHPAPEKSSKVSEQLKCCSGILKEMFAKKH 369
            + +   +  E  +P+K    P   VP     P P+KS                      
Sbjct: 267 SEDSSSDEEEEQKKPMKNKPGPYSSVPPPSA-PPPKKS---------------------- 303

Query: 370 AAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNC 429
                          LG       ++    + + +   +  +    +E     + + S  
Sbjct: 304 ---------------LGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKA 348

Query: 430 YKYNPPDHEVVAMARKLQDVFEMRFAKMPDEP--------EEPVVAVSSPAVPPPTKVVA 481
               PP  +    +    D       + P +P         +P V   SPAV P      
Sbjct: 349 TTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQ 408

Query: 482 PPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEK 541
           P           +DS SS ++S     ++  ++    K      AALS P +  P+    
Sbjct: 409 PVGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRD 468

Query: 542 DKKEKKKEKHKRKEEVEENKKSKAKEPP-----------PKKTKK------NNSSNSNVS 584
              +   +    +EE E+  KS  K+ P           P   KK      N+SS+ + S
Sbjct: 469 SSSD--SDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSS 526

Query: 585 KKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSL 644
           ++E   +K K  P  ++ + +    ++ +  +      N    E+  +   ++ S+  SL
Sbjct: 527 EEEEEKLKGKGSPRPQAPKANGTSALTAQNGKAAK---NSEEEEEEKKKAAVVVSKSGSL 583

Query: 645 KNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESE 704
           K    +E   + ET +   ++ L+   T   RKK + +A        SS  +     E E
Sbjct: 584 KKRKQNEAAKEAETPQAKKIK-LQTPNTFPKRKKGEKRA--------SSPFRRVREEEIE 634

Query: 705 SSSESSSSDSEDSETGPA 722
             S   + +S D++ G A
Sbjct: 635 VDSR-VADNSFDAKRGAA 651



 Score = 57.8 bits (138), Expect = 4e-08
 Identities = 75/311 (24%), Positives = 129/311 (41%), Gaps = 71/311 (22%)

Query: 459 DEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQL 518
           +E EE     +  A  P  +V  PP  + + +  SS S+ S+DD +EE  Q+   +Q+ +
Sbjct: 92  EEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASESSSSEESSDDDDEE-DQKKQPVQKGV 150

Query: 519 KAVHEQLAALSQPQQNKPKKKEKD-KKEKKKEKHKRKEEVEENKKSKAKEPP------PK 571
           K   +  AA + P++ K    + D   E +  K+++ +      K++ K PP      PK
Sbjct: 151 KP--QAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPK 208

Query: 572 ---------KTKKNNSSNSNVSKKE-----------------PAPMKSKPPPTYES---- 601
                     +  ++SS+S+ S++E                  AP+K+   PT +S    
Sbjct: 209 IANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSE 268

Query: 602 -----EEEDKCKPMSYEEKRQLSLDINKLPGEK--LGRVVHIIQSREPSLKNSNPDEIEI 654
                EEE++ KPM  +     S+     P  K  LG      Q  + +++   P E   
Sbjct: 269 DSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLG-----TQPPKKAVEKQQPVESSE 323

Query: 655 DFETLKPSTLRELERYVTSCLRKK---RKPQAEKVDVIAGSSKMKGFSSSESESSSESSS 711
           D      S+  E ++  T  +  K   + P A+K                 +ESSS+SS 
Sbjct: 324 DSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKA----------------AESSSDSSD 367

Query: 712 SDSEDSETGPA 722
           SDS + +  P+
Sbjct: 368 SDSSEDDEAPS 378



 Score = 53.1 bits (126), Expect = 9e-07
 Identities = 57/243 (23%), Positives = 101/243 (41%), Gaps = 37/243 (15%)

Query: 482 PPSSSDSSSDSSSDSDSSTDDSEEER---AQRLAELQEQLKAVHEQLAALSQPQQNKPKK 538
           P +       SSSDS+ S+++ EE +   A++ A   +++     + AA +    +  + 
Sbjct: 73  PVAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASESSSSEES 132

Query: 539 KEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPT 598
            + D +E +K++  +K    + K +KA   PPKK K ++S + + S+ EP P   KP   
Sbjct: 133 SDDDDEEDQKKQPVQKGVKPQAKAAKA---PPKKAKSSDSDSDSSSEDEP-PKNQKP--- 185

Query: 599 YESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFET 658
                  K  P++ + +        K P +       I   +  S  +S+      D   
Sbjct: 186 -------KITPVTVKAQ-------TKAPPKPARAAPKIANGKAASSSSSSSSSSSSD--- 228

Query: 659 LKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSE 718
                  + E    +   KK  P   K  V+A +      + +   SSSE SSSD E+ +
Sbjct: 229 -------DSEEEKAAATPKKTVP---KKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQ 278

Query: 719 TGP 721
             P
Sbjct: 279 KKP 281


>gi|91176325 bromodomain adjacent to zinc finger domain, 2A [Homo
            sapiens]
          Length = 1905

 Score = 68.2 bits (165), Expect = 3e-11
 Identities = 48/140 (34%), Positives = 70/140 (50%), Gaps = 10/140 (7%)

Query: 320  QRRESSRPVKPPKKDVPDSQQHPAPEKSSKVS-----EQLKCCSGILKEMFAKKHAAYAW 374
            +RR   R  + P      S++  +P K  ++S       L  C  IL EM  + H A AW
Sbjct: 1760 RRRVLLRGRESPAAGPRYSEEGLSPSKRRRLSMRNHHSDLTFCEIILMEM--ESHDA-AW 1816

Query: 375  PFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNP 434
            PF +PV+   +    Y  IIK+PMD ST++ +L    Y  ++EF AD  L+F NC  +N 
Sbjct: 1817 PFLEPVNPRLVS--GYRRIIKNPMDFSTMRERLLRGGYTSSEEFAADALLVFDNCQTFNE 1874

Query: 435  PDHEVVAMARKLQDVFEMRF 454
             D EV      ++  FE R+
Sbjct: 1875 DDSEVGKAGHIMRRFFESRW 1894



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 31/119 (26%), Positives = 59/119 (49%), Gaps = 6/119 (5%)

Query: 49   ETSNPNKPKRQTNQLQY----LLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTP 104
            E  +P+K +R + +  +       ++L  +  H  AWPF +PV+   ++   Y +IIK P
Sbjct: 1780 EGLSPSKRRRLSMRNHHSDLTFCEIILMEMESHDAAWPFLEPVNPRLVS--GYRRIIKNP 1837

Query: 105  MDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINE 163
            MD  T+++RL    Y +++E   D   +F NC  +N+   ++      + + F  +  E
Sbjct: 1838 MDFSTMRERLLRGGYTSSEEFAADALLVFDNCQTFNEDDSEVGKAGHIMRRFFESRWEE 1896



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 37/155 (23%), Positives = 68/155 (43%), Gaps = 9/155 (5%)

Query: 474 PPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQ 533
           PP  K+    + +D+      ++  + +  EE++A+     ++  + V       +   Q
Sbjct: 676 PPKVKITELLNKTDNRPLKKLEAQETLN--EEDKAKIAKSKKKMRQKVQRGECQTTIQGQ 733

Query: 534 NKPKKKEKDKKEKKKEKHKRKEEVEENK------KSKAKEPPPKKTKKNNSSNSNVSKKE 587
            + K+K++ K  K+KE  K+K + E+ K      K K K    KK K        V+K +
Sbjct: 734 ARNKRKQETKSLKQKEA-KKKSKAEKEKGKTKQEKLKEKVKREKKEKVKMKEKEEVTKAK 792

Query: 588 PAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDI 622
           PA    K   T    EE + + M  EE ++ + D+
Sbjct: 793 PACKADKTLATQRRLEERQRQQMILEEMKKPTEDM 827



 Score = 35.8 bits (81), Expect = 0.14
 Identities = 37/141 (26%), Positives = 53/141 (37%), Gaps = 30/141 (21%)

Query: 197  PNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQ 256
            P+++     P    P   P P +A   P P       +   +   +P     TPPP   +
Sbjct: 1290 PDSSPGKLDPAPSQPPEEPEPDEAESSPDPQA-----LWFNISAQMPCNAAPTPPPAVSE 1344

Query: 257  PQPPPAPAPQPVQSHPPI---IAATP-QPVKTKK------GVKRKADTTTPTTIDPIHEP 306
             Q  P P+PQ + S  P+    AA P  PV+           KR+A            +P
Sbjct: 1345 DQ--PTPSPQQLASSKPMNRPSAANPCSPVQFSSTPLAGLAPKRRAG-----------DP 1391

Query: 307  PSLPPEPKTTKLGQRRESSRP 327
              +P  P  T LGQ +   RP
Sbjct: 1392 GEMPQSP--TGLGQPKRRGRP 1410


>gi|153792074 proline rich 12 [Homo sapiens]
          Length = 2036

 Score = 68.2 bits (165), Expect = 3e-11
 Identities = 35/78 (44%), Positives = 38/78 (48%), Gaps = 2/78 (2%)

Query: 204  TPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAP 263
            TPP   TPQP PPP    P P     P L+  TP     PP P   PPP  P P PPP P
Sbjct: 1460 TPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLP-PPPPPAMPSPPPPPPP 1518

Query: 264  APQPVQSHPPIIAATPQP 281
            A  P+ + PP   A P P
Sbjct: 1519 AAAPLAA-PPEEPAAPSP 1535



 Score = 63.9 bits (154), Expect = 5e-10
 Identities = 94/415 (22%), Positives = 143/415 (34%), Gaps = 54/415 (13%)

Query: 205  PPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPP----QPLQTPPPVP---PQP 257
            P  T TP   PP   A   P P   P L       T  PP    +P  TPPP P   PQP
Sbjct: 1413 PKDTSTPD-GPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQP 1471

Query: 258  QPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTK 317
             PPP P    + S PP++A TP                 P    P    P  PP P    
Sbjct: 1472 PPPPPPPQPALPSPPPLVAPTP---------SSPPPPPLPPPPPPAMPSPPPPPPPAAAP 1522

Query: 318  LGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQLKCCSGILKE--------MFAKKH 369
            L    E      P   ++PD++    P   +K  E    C    +E        +F ++ 
Sbjct: 1523 LAAPPEEPAAPSPEDPELPDTR----PLHLAKKQETAAVCGETDEEAGESGGEGIFRERD 1578

Query: 370  AAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAR---EYRDAQ-EFGADVRLM 425
                    +  D+ +L L       + P  +  ++  L  +   E +D Q +F A     
Sbjct: 1579 EF----VIRAEDIPSLKL--ALQTGREPPPIWRVQKALLQKFTPEIKDGQRQFCAT---- 1628

Query: 426  FSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPPPTKVVAPPSS 485
             SN   Y          A+       ++F +  ++ +   V    P   PP  V     +
Sbjct: 1629 -SNYLGY-------FGDAKNRYQRLYVKFLENVNKKDYVRVCARKPWHRPPVPVRRSGQA 1680

Query: 486  SDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQP-QQNKPKKKEKDKK 544
             +  S   S +      +   + +   +   +         A+ +P    KP      +K
Sbjct: 1681 KNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPAPEKPSLLRPVEK 1740

Query: 545  EKKKEKHKRKEEV--EENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPP 597
            EK+KEK  R E     E   S  +  P +       + S + K  P  +K++PPP
Sbjct: 1741 EKEKEKVTRGERPLRGERATSGRQTRPERSLATGQPATSRLPKARPTKVKAEPPP 1795



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 54/251 (21%), Positives = 89/251 (35%), Gaps = 62/251 (24%)

Query: 142 PGDDIVLMAEALEKLFLQKI-------NELPTEETEIMIVQAKGRGRGRKETGTAKPGVS 194
           PG    L  E  ++  LQ +       +E  T   E+ + + K + +G +  G    G++
Sbjct: 684 PGTPYELAKEDPQRYHLQSVIRTSASLDEGATAALELGLGRLKEKKKGPERGGETPEGLA 743

Query: 195 T-----------VPNTTQASTPPQTQTPQPNPPPVQATPH-----------------PFP 226
           T           +    Q S PP    P P     Q TPH                 P P
Sbjct: 744 TSVVHYGAGAKELGAFLQKSPPP----PPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPP 799

Query: 227 AVTPDLIVQTPVMT---------VVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAA 277
            + P ++   P  +         ++ P      P  PP P PPP P P  +++H  + + 
Sbjct: 800 QLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAH--LRSH 857

Query: 278 TPQPVKTKKGVKRKADTTTPTTIDPI---HEPPSLPPEPKTTKLGQRRESSRPVKPPKKD 334
             +P      ++ +     P  +  +    EP  LPP P  T +G       P     KD
Sbjct: 858 GLEPAAPSPRLRPEESLDPPGAMQELLGALEP--LPPAPGDTGVG-------PPNSEGKD 908

Query: 335 VPDSQQHPAPE 345
              + + P+P+
Sbjct: 909 PAGAYRSPSPQ 919



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 42/162 (25%), Positives = 59/162 (36%), Gaps = 27/162 (16%)

Query: 205  PPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPA 264
            P +     P  P +   P+  P + P  +   P + ++   P Q  PP PP P PPPAPA
Sbjct: 995  PGRASGAGPETPGLGLDPNKPPEL-PSTVNAEP-LGLIQSGPHQAAPPPPPPPPPPPAPA 1052

Query: 265  PQPVQS-HPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPE----------- 312
             +P      PI  +T    K KK +K  +         P   P  L  +           
Sbjct: 1053 SEPKGGLTSPIFCST----KPKKLLKTSSFHLLRRRDPPFQTPKKLYAQEYEFEADEDKA 1108

Query: 313  --PKTTKLGQRRE-------SSRPVKPPKKDVPDSQQHPAPE 345
              P   +L  RR         SRP   P  D+     +P P+
Sbjct: 1109 DVPADIRLNPRRLPDLVSSCRSRPALSPLGDIDFCPPNPGPD 1150



 Score = 38.5 bits (88), Expect = 0.022
 Identities = 40/172 (23%), Positives = 60/172 (34%), Gaps = 31/172 (18%)

Query: 189 AKPGVSTVPNTTQASTPPQTQT----PQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPP 244
           A PG ST P+++  S      +    P P P  +     PF      L+    V+ + P 
Sbjct: 135 ALPGSSTFPSSSALSAYQHPASFGSRPFPVPSSLSLQDPPFSPPANGLLSPHDVLHLKPS 194

Query: 245 Q-------------------------PLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATP 279
           Q                         P QTPP  P  P PPP P   P Q +  ++A++ 
Sbjct: 195 QAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFN--LLASSS 252

Query: 280 QPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPP 331
                 +    +    +     P     +LP +    K  QR  S++P  PP
Sbjct: 253 AAAAAAEQSSPQLYNFSGAAPGPPPPERALPRQDTVIKHYQRPASAQPPPPP 304



 Score = 34.7 bits (78), Expect = 0.32
 Identities = 29/122 (23%), Positives = 46/122 (37%), Gaps = 20/122 (16%)

Query: 215  PPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPA---PQPVQSH 271
            PPP    P P P        +TP  T     P QTP    P+P  P  P+   P   +  
Sbjct: 1692 PPPKAPAPPPKP--------ETPEKTTSEKPPEQTPETAMPEPPAPEKPSLLRPVEKEKE 1743

Query: 272  PPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPP 331
               +    +P++ ++    +   T P       E      +P T++L + R +    +PP
Sbjct: 1744 KEKVTRGERPLRGERATSGR--QTRP-------ERSLATGQPATSRLPKARPTKVKAEPP 1794

Query: 332  KK 333
             K
Sbjct: 1795 PK 1796



 Score = 33.9 bits (76), Expect = 0.54
 Identities = 45/188 (23%), Positives = 66/188 (35%), Gaps = 32/188 (17%)

Query: 178  GRGRGRKETGTAKPGVSTVPN-------TTQA-------STPPQTQTPQPNPPPVQATPH 223
            GR  G    G   PG+   PN       T  A       S P Q   P P PPP    P 
Sbjct: 996  GRASG---AGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPPPPPPPP----PP 1048

Query: 224  PFPAVTPDLIVQTPVM-TVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQ-- 280
            P PA  P   + +P+  +  P + L+T      + + PP   P+ + +      A     
Sbjct: 1049 PAPASEPKGGLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQTPKKLYAQEYEFEADEDKA 1108

Query: 281  --PVKTKKGVKRKADTTTP----TTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKD 334
              P   +   +R  D  +       + P+ +    PP P     G RR   +P K  +  
Sbjct: 1109 DVPADIRLNPRRLPDLVSSCRSRPALSPLGDIDFCPPNPGPD--GPRRRGRKPTKAKRDG 1166

Query: 335  VPDSQQHP 342
             P  +  P
Sbjct: 1167 PPRPRGRP 1174



 Score = 33.9 bits (76), Expect = 0.54
 Identities = 20/68 (29%), Positives = 26/68 (38%), Gaps = 17/68 (25%)

Query: 203  STPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPP--PVPPQPQPP 260
            S+PP    P P PP + + P P P                   PL  PP  P  P P+ P
Sbjct: 1494 SSPPPPPLPPPPPPAMPSPPPPPPPAA---------------APLAAPPEEPAAPSPEDP 1538

Query: 261  PAPAPQPV 268
              P  +P+
Sbjct: 1539 ELPDTRPL 1546



 Score = 32.0 bits (71), Expect = 2.1
 Identities = 15/33 (45%), Positives = 18/33 (54%), Gaps = 1/33 (3%)

Query: 249  TPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQP 281
            TPP  PP+  PP  PA + +Q  PP   A P P
Sbjct: 1304 TPPLSPPKSVPPSVPA-RGLQPQPPATPAVPHP 1335


>gi|14670392 bromodomain adjacent to zinc finger domain, 1B [Homo
            sapiens]
          Length = 1483

 Score = 67.4 bits (163), Expect = 4e-11
 Identities = 45/158 (28%), Positives = 74/158 (46%), Gaps = 7/158 (4%)

Query: 306  PPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSK-VSEQLKCCSGILKEM 364
            PP+     +  K       S+P  PP  D    +     ++SS+  S +L+ C  IL ++
Sbjct: 1296 PPAARSGRRPGKKPHSTRRSQPKAPPVDDAEVDELVLQTKRSSRRQSLELQKCEEILHKI 1355

Query: 365  FAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRL 424
               +   ++WPF +PV  +     DY D+I HPMD  T+++K     YR  QEF  D++ 
Sbjct: 1356 VKYR---FSWPFREPVTRDEA--EDYYDVITHPMDFQTVQNKCSCGSYRSVQEFLTDMKQ 1410

Query: 425  MFSNCYKYN-PPDHEVVAMARKLQDVFEMRFAKMPDEP 461
            +F+N   YN    H +  M +  Q +  +    +P  P
Sbjct: 1411 VFTNAEVYNCRGSHVLSCMVKTEQCLVALLHKHLPGHP 1448



 Score = 63.5 bits (153), Expect = 6e-10
 Identities = 36/121 (29%), Positives = 65/121 (53%), Gaps = 5/121 (4%)

Query: 27   STTQAQAQPQPANAASTNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQP 86
            ST ++Q +  P + A  +    +T   ++  RQ+ +LQ    ++ K + K++F+WPF++P
Sbjct: 1311 STRRSQPKAPPVDDAEVDELVLQTKRSSR--RQSLELQKCEEILHKIV-KYRFSWPFREP 1367

Query: 87   VDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDI 146
            V   +    DYY +I  PMD  T++ +     Y + QE + D   +FTN  +YN  G  +
Sbjct: 1368 V--TRDEAEDYYDVITHPMDFQTVQNKCSCGSYRSVQEFLTDMKQVFTNAEVYNCRGSHV 1425

Query: 147  V 147
            +
Sbjct: 1426 L 1426



 Score = 35.4 bits (80), Expect = 0.19
 Identities = 28/97 (28%), Positives = 50/97 (51%), Gaps = 9/97 (9%)

Query: 503 SEEERAQRLAELQEQLKAVHEQL------AALSQPQQN---KPKKKEKDKKEKKKEKHKR 553
           S E+RA+   EL+  ++  +E L      A++S+ Q+    K K++E  KK K+K K +R
Sbjct: 507 SSEDRARLPEELRSLVQKRYELLEHKKRWASMSEEQRKEYLKKKREELKKKLKEKAKERR 566

Query: 554 KEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAP 590
           ++E+ E  + + +    + T KN  +   V   E  P
Sbjct: 567 EKEMLERLEKQKRYEDQELTGKNLPAFRLVDTPEGLP 603



 Score = 31.2 bits (69), Expect = 3.5
 Identities = 32/145 (22%), Positives = 63/145 (43%), Gaps = 18/145 (12%)

Query: 533  QNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNN--------SSNSNVS 584
            +    +  +D +  ++E+ + +EE EE+ +       P+KT +           S     
Sbjct: 1247 EESASEDSEDDESDEEEEEEEEEEEEEDYEVAGLRLRPRKTIRGKHSVIPPAARSGRRPG 1306

Query: 585  KKEPAPMKSKP-PPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQS---R 640
            KK  +  +S+P  P  +  E D+    +    R+ SL++ K   E L ++V    S   R
Sbjct: 1307 KKPHSTRRSQPKAPPVDDAEVDELVLQTKRSSRRQSLELQKCE-EILHKIVKYRFSWPFR 1365

Query: 641  EPSLKNSNPDEIEI-----DFETLK 660
            EP  ++   D  ++     DF+T++
Sbjct: 1366 EPVTRDEAEDYYDVITHPMDFQTVQ 1390



 Score = 30.8 bits (68), Expect = 4.6
 Identities = 39/126 (30%), Positives = 54/126 (42%), Gaps = 32/126 (25%)

Query: 499 STDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVE 558
           S  D  E R Q  AEL +      E+LA L         K+E DKK  + EK KRKE   
Sbjct: 761 SVQDHMETRQQMSAELWK------ERLAVL---------KEENDKK--RAEKQKRKEMEA 803

Query: 559 ENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQL 618
           +NK++   E    KT +         KKE      K  P  ++E ED     + + +R L
Sbjct: 804 KNKENGKVENGLGKTDR---------KKEIV----KFEPQVDTEAEDMIS--AVKSRRLL 848

Query: 619 SLDINK 624
           ++   K
Sbjct: 849 AIQAKK 854


>gi|34452709 bromodomain containing 8 isoform 3 [Homo sapiens]
          Length = 757

 Score = 67.4 bits (163), Expect = 4e-11
 Identities = 68/233 (29%), Positives = 96/233 (41%), Gaps = 42/233 (18%)

Query: 255 PQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTI----------DPIH 304
           P+    P+    P++   P+ A T    +    +K ++ T   + I          D + 
Sbjct: 474 PESMLSPSHGSNPIED--PLEAETQHKFEMSDSLKEESGTIFGSQIKDAPGEDEEEDGVS 531

Query: 305 EPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDS--------QQHPAPEK--SSKVSEQL 354
           E  SL  EPK    G+   S    +PP  +  D         Q H   +   SS  S Q 
Sbjct: 532 EAASLE-EPKEEDQGEGYLSEMDNEPPVSESDDGFSIHNATLQSHTLADSIPSSPASSQF 590

Query: 355 KCCSGILKEMFAKK--------------HAAYAWPFYKPV-DVEALGLHDYCDIIKHPMD 399
             CS   + + A+K              +  YA  F +PV D  A G H    I++ PMD
Sbjct: 591 SVCSEDQEAIQAQKIWKKAIMLVWRAAANHRYANVFLQPVTDDIAPGYHS---IVQRPMD 647

Query: 400 MSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQ-DVFE 451
           +STIK  +E    R   EF  D+ LMF N   YN  DH+V  MA ++Q DV E
Sbjct: 648 LSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQRDVLE 700



 Score = 67.0 bits (162), Expect = 6e-11
 Identities = 48/171 (28%), Positives = 81/171 (47%), Gaps = 17/171 (9%)

Query: 36  QPANAASTNPPPPETSNPN--KPKRQTNQLQYLLRVVLKTLWK----HQFAWPFQQPV-D 88
           Q    A + P  P +S  +     ++  Q Q + +  +  +W+    H++A  F QPV D
Sbjct: 573 QSHTLADSIPSSPASSQFSVCSEDQEAIQAQKIWKKAIMLVWRAAANHRYANVFLQPVTD 632

Query: 89  AVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVL 148
            +    P Y+ I++ PMD+ TIKK +EN    +  E  +D   MF N  +YN    D+  
Sbjct: 633 DIA---PGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNSSDHDVYH 689

Query: 149 MAEALEKLFLQKINE-------LPTEETEIMIVQAKGRGRGRKETGTAKPG 192
           MA  +++  L++I +       + T E+ I     +GR   RK+  + K G
Sbjct: 690 MAVEMQRDVLEQIQQFLATQLIMQTSESGISAKSLRGRDSTRKQDASEKDG 740


>gi|34452707 bromodomain containing 8 isoform 2 [Homo sapiens]
          Length = 1235

 Score = 67.4 bits (163), Expect = 4e-11
 Identities = 68/233 (29%), Positives = 96/233 (41%), Gaps = 42/233 (18%)

Query: 255 PQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTI----------DPIH 304
           P+    P+    P++   P+ A T    +    +K ++ T   + I          D + 
Sbjct: 580 PESMLSPSHGSNPIED--PLEAETQHKFEMSDSLKEESGTIFGSQIKDAPGEDEEEDGVS 637

Query: 305 EPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDS--------QQHPAPEK--SSKVSEQL 354
           E  SL  EPK    G+   S    +PP  +  D         Q H   +   SS  S Q 
Sbjct: 638 EAASLE-EPKEEDQGEGYLSEMDNEPPVSESDDGFSIHNATLQSHTLADSIPSSPASSQF 696

Query: 355 KCCSGILKEMFAKK--------------HAAYAWPFYKPV-DVEALGLHDYCDIIKHPMD 399
             CS   + + A+K              +  YA  F +PV D  A G H    I++ PMD
Sbjct: 697 SVCSEDQEAIQAQKIWKKAIMLVWRAAANHRYANVFLQPVTDDIAPGYHS---IVQRPMD 753

Query: 400 MSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQ-DVFE 451
           +STIK  +E    R   EF  D+ LMF N   YN  DH+V  MA ++Q DV E
Sbjct: 754 LSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQRDVLE 806



 Score = 66.2 bits (160), Expect = 1e-10
 Identities = 48/172 (27%), Positives = 81/172 (47%), Gaps = 17/172 (9%)

Query: 36  QPANAASTNPPPPETSNPN--KPKRQTNQLQYLLRVVLKTLWK----HQFAWPFQQPV-D 88
           Q    A + P  P +S  +     ++  Q Q + +  +  +W+    H++A  F QPV D
Sbjct: 679 QSHTLADSIPSSPASSQFSVCSEDQEAIQAQKIWKKAIMLVWRAAANHRYANVFLQPVTD 738

Query: 89  AVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVL 148
            +    P Y+ I++ PMD+ TIKK +EN    +  E  +D   MF N  +YN    D+  
Sbjct: 739 DIA---PGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNSSDHDVYH 795

Query: 149 MAEALEKLFLQKINE-------LPTEETEIMIVQAKGRGRGRKETGTAKPGV 193
           MA  +++  L++I +       + T E+ I     +GR   RK+  + K  V
Sbjct: 796 MAVEMQRDVLEQIQQFLATQLIMQTSESGISAKSLRGRDSTRKQDASEKDSV 847



 Score = 53.1 bits (126), Expect = 9e-07
 Identities = 29/77 (37%), Positives = 44/77 (57%), Gaps = 4/77 (5%)

Query: 372  YAWPFYKPV-DVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCY 430
            ++ PF KPV + +A G   Y D++K PMD++++K  L     R   +F  D+ LMF N  
Sbjct: 1124 FSSPFLKPVSERQAPG---YKDVVKRPMDLTSLKRNLSKGRIRTMAQFLRDLMLMFQNAV 1180

Query: 431  KYNPPDHEVVAMARKLQ 447
             YN  DH V  MA +++
Sbjct: 1181 MYNDSDHHVYHMAVEMR 1197



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 29/103 (28%), Positives = 50/103 (48%), Gaps = 6/103 (5%)

Query: 66   LLRVVLKTLWK----HQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWN 121
            L +  L  +WK    H+F+ PF +PV   +   P Y  ++K PMD+ ++K+ L       
Sbjct: 1107 LFKKTLLPVWKMIASHRFSSPFLKPVS--ERQAPGYKDVVKRPMDLTSLKRNLSKGRIRT 1164

Query: 122  AQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINEL 164
              + ++D   MF N  +YN     +  MA  + +  L++I  L
Sbjct: 1165 MAQFLRDLMLMFQNAVMYNDSDHHVYHMAVEMRREVLEQIQVL 1207



 Score = 33.5 bits (75), Expect = 0.71
 Identities = 25/83 (30%), Positives = 33/83 (39%), Gaps = 9/83 (10%)

Query: 186 TGTAKPGVSTVPNT--------TQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTP 237
           T  A P  S  P          TQ +TP  + T   + PPV+  P P  +V+   IV  P
Sbjct: 254 TVAASPAASGAPTLSRLLEAGPTQFTTPLASFTTVASEPPVKLVPPPVESVSQATIVMMP 313

Query: 238 VMTVVPPQP-LQTPPPVPPQPQP 259
            +      P + T   V P  QP
Sbjct: 314 ALPAPSSAPAVSTTESVAPVSQP 336


>gi|34452705 bromodomain containing 8 isoform 1 [Homo sapiens]
          Length = 951

 Score = 67.4 bits (163), Expect = 4e-11
 Identities = 68/233 (29%), Positives = 96/233 (41%), Gaps = 42/233 (18%)

Query: 255 PQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTI----------DPIH 304
           P+    P+    P++   P+ A T    +    +K ++ T   + I          D + 
Sbjct: 653 PESMLSPSHGSNPIED--PLEAETQHKFEMSDSLKEESGTIFGSQIKDAPGEDEEEDGVS 710

Query: 305 EPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDS--------QQHPAPEK--SSKVSEQL 354
           E  SL  EPK    G+   S    +PP  +  D         Q H   +   SS  S Q 
Sbjct: 711 EAASLE-EPKEEDQGEGYLSEMDNEPPVSESDDGFSIHNATLQSHTLADSIPSSPASSQF 769

Query: 355 KCCSGILKEMFAKK--------------HAAYAWPFYKPV-DVEALGLHDYCDIIKHPMD 399
             CS   + + A+K              +  YA  F +PV D  A G H    I++ PMD
Sbjct: 770 SVCSEDQEAIQAQKIWKKAIMLVWRAAANHRYANVFLQPVTDDIAPGYHS---IVQRPMD 826

Query: 400 MSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQ-DVFE 451
           +STIK  +E    R   EF  D+ LMF N   YN  DH+V  MA ++Q DV E
Sbjct: 827 LSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQRDVLE 879



 Score = 66.2 bits (160), Expect = 1e-10
 Identities = 48/172 (27%), Positives = 81/172 (47%), Gaps = 17/172 (9%)

Query: 36  QPANAASTNPPPPETSNPN--KPKRQTNQLQYLLRVVLKTLWK----HQFAWPFQQPV-D 88
           Q    A + P  P +S  +     ++  Q Q + +  +  +W+    H++A  F QPV D
Sbjct: 752 QSHTLADSIPSSPASSQFSVCSEDQEAIQAQKIWKKAIMLVWRAAANHRYANVFLQPVTD 811

Query: 89  AVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVL 148
            +    P Y+ I++ PMD+ TIKK +EN    +  E  +D   MF N  +YN    D+  
Sbjct: 812 DIA---PGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNSSDHDVYH 868

Query: 149 MAEALEKLFLQKINE-------LPTEETEIMIVQAKGRGRGRKETGTAKPGV 193
           MA  +++  L++I +       + T E+ I     +GR   RK+  + K  V
Sbjct: 869 MAVEMQRDVLEQIQQFLATQLIMQTSESGISAKSLRGRDSTRKQDASEKDSV 920



 Score = 33.5 bits (75), Expect = 0.71
 Identities = 25/83 (30%), Positives = 33/83 (39%), Gaps = 9/83 (10%)

Query: 186 TGTAKPGVSTVPNT--------TQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTP 237
           T  A P  S  P          TQ +TP  + T   + PPV+  P P  +V+   IV  P
Sbjct: 327 TVAASPAASGAPTLSRLLEAGPTQFTTPLASFTTVASEPPVKLVPPPVESVSQATIVMMP 386

Query: 238 VMTVVPPQP-LQTPPPVPPQPQP 259
            +      P + T   V P  QP
Sbjct: 387 ALPAPSSAPAVSTTESVAPVSQP 409


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.307    0.126    0.362 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,727,316
Number of Sequences: 37866
Number of extensions: 2386995
Number of successful extensions: 76249
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1313
Number of HSP's successfully gapped in prelim test: 2055
Number of HSP's that attempted gapping in prelim test: 22943
Number of HSP's gapped (non-prelim): 26658
length of query: 722
length of database: 18,247,518
effective HSP length: 110
effective length of query: 612
effective length of database: 14,082,258
effective search space: 8618341896
effective search space used: 8618341896
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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