Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 7656991
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7656991 coronin, actin binding protein, 1C isoform 1 [Homo
sapiens]
(474 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7656991 coronin, actin binding protein, 1C isoform 1 [Homo sa... 970 0.0
gi|65787364 coronin, actin binding protein, 1B [Homo sapiens] 757 0.0
gi|14149734 coronin, actin binding protein, 1B [Homo sapiens] 757 0.0
gi|109627650 coronin 6 [Homo sapiens] 698 0.0
gi|5902134 coronin, actin binding protein, 1A [Homo sapiens] 645 0.0
gi|148529011 coronin, actin binding protein, 2B [Homo sapiens] 417 e-117
gi|209529711 coronin, actin binding protein, 2A [Homo sapiens] 410 e-114
gi|16554585 coronin, actin binding protein, 2A [Homo sapiens] 410 e-114
gi|168229161 coronin 7 [Homo sapiens] 233 2e-61
gi|20143912 WD repeat and SOCS box-containing 1 isoform 2 [Homo ... 71 2e-12
gi|18677720 WD repeat and SOCS box-containing 1 isoform 1 [Homo ... 70 3e-12
gi|207029439 retinoblastoma binding protein 4 isoform c [Homo sa... 69 9e-12
gi|207029415 retinoblastoma binding protein 4 isoform b [Homo sa... 69 9e-12
gi|5032027 retinoblastoma binding protein 4 isoform a [Homo sapi... 69 9e-12
gi|4506439 retinoblastoma binding protein 7 [Homo sapiens] 66 6e-11
gi|169403944 WD repeat domain 26 isoform b [Homo sapiens] 65 1e-10
gi|55743153 WD repeat domain 26 isoform a [Homo sapiens] 65 1e-10
gi|55743149 WD repeat domain 17 isoform 2 [Homo sapiens] 64 2e-10
gi|31317311 WD repeat domain 17 isoform 1 [Homo sapiens] 64 2e-10
gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens] 64 2e-10
gi|4885105 chromatin assembly factor 1 subunit B [Homo sapiens] 62 1e-09
gi|4505731 peroxisomal biogenesis factor 7 [Homo sapiens] 61 2e-09
gi|19913371 transducin (beta)-like 1 X-linked receptor 1 [Homo s... 60 4e-09
gi|113865883 WD repeat domain 38 [Homo sapiens] 60 6e-09
gi|213021190 transducin beta-like 1X isoform b [Homo sapiens] 59 7e-09
gi|213021188 transducin beta-like 1X isoform b [Homo sapiens] 59 7e-09
gi|213021186 transducin beta-like 1X isoform a [Homo sapiens] 59 7e-09
gi|5032159 transducin beta-like 1X isoform a [Homo sapiens] 59 7e-09
gi|19913367 transducin beta-like 1Y [Homo sapiens] 59 7e-09
gi|19913365 transducin beta-like 1Y [Homo sapiens] 59 7e-09
>gi|7656991 coronin, actin binding protein, 1C isoform 1 [Homo
sapiens]
Length = 474
Score = 970 bits (2507), Expect = 0.0
Identities = 474/474 (100%), Positives = 474/474 (100%)
Query: 1 MRRVVRQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSSFCAVNPRFVAIIIEASGGGAFLV 60
MRRVVRQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSSFCAVNPRFVAIIIEASGGGAFLV
Sbjct: 1 MRRVVRQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSSFCAVNPRFVAIIIEASGGGAFLV 60
Query: 61 LPLHKTGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLT 120
LPLHKTGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLT
Sbjct: 61 LPLHKTGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLT 120
Query: 121 EPVVILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNV 180
EPVVILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNV
Sbjct: 121 EPVVILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNV 180
Query: 181 SWNRNGSLICTASKDKKVRVIDPRKQEIVAEKEKAHEGARPMRAIFLADGNVFTTGFSRM 240
SWNRNGSLICTASKDKKVRVIDPRKQEIVAEKEKAHEGARPMRAIFLADGNVFTTGFSRM
Sbjct: 181 SWNRNGSLICTASKDKKVRVIDPRKQEIVAEKEKAHEGARPMRAIFLADGNVFTTGFSRM 240
Query: 241 SERQLALWNPKNMQEPIALHEMDTSNGVLLPFYDPDTSIIYLCGKGDSSIRYFEITDESP 300
SERQLALWNPKNMQEPIALHEMDTSNGVLLPFYDPDTSIIYLCGKGDSSIRYFEITDESP
Sbjct: 241 SERQLALWNPKNMQEPIALHEMDTSNGVLLPFYDPDTSIIYLCGKGDSSIRYFEITDESP 300
Query: 301 YVHYLNTFSSKEPQRGMGYMPKRGLDVNKCEIARFFKLHERKCEPIIMTVPRKSDLFQDD 360
YVHYLNTFSSKEPQRGMGYMPKRGLDVNKCEIARFFKLHERKCEPIIMTVPRKSDLFQDD
Sbjct: 301 YVHYLNTFSSKEPQRGMGYMPKRGLDVNKCEIARFFKLHERKCEPIIMTVPRKSDLFQDD 360
Query: 361 LYPDTAGPEAALEAEEWFEGKNADPILISLKHGYIPGKNRDLKVVKKNILDSKPTANKKC 420
LYPDTAGPEAALEAEEWFEGKNADPILISLKHGYIPGKNRDLKVVKKNILDSKPTANKKC
Sbjct: 361 LYPDTAGPEAALEAEEWFEGKNADPILISLKHGYIPGKNRDLKVVKKNILDSKPTANKKC 420
Query: 421 DLISIPKKTTDTASVQNEAKLDEILKEIKSIKDTICNQDERISKLEQQMAKIAA 474
DLISIPKKTTDTASVQNEAKLDEILKEIKSIKDTICNQDERISKLEQQMAKIAA
Sbjct: 421 DLISIPKKTTDTASVQNEAKLDEILKEIKSIKDTICNQDERISKLEQQMAKIAA 474
>gi|65787364 coronin, actin binding protein, 1B [Homo sapiens]
Length = 489
Score = 757 bits (1954), Expect = 0.0
Identities = 350/481 (72%), Positives = 415/481 (86%), Gaps = 10/481 (2%)
Query: 2 RRVVRQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSSFCAVNPRFVAIIIEASGGGAFLVL 61
R+VVRQSKFRHVFGQ VKNDQCY+DIRVSRVTWDS+FCAVNP+F+A+I+EASGGGAFLVL
Sbjct: 4 RKVVRQSKFRHVFGQPVKNDQCYEDIRVSRVTWDSTFCAVNPKFLAVIVEASGGGAFLVL 63
Query: 62 PLHKTGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTE 121
PL KTGRIDK+YPTVCGHTGPVLDIDWCPHND+VIASGSEDCTVMVWQIPENGLT LTE
Sbjct: 64 PLSKTGRIDKAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTE 123
Query: 122 PVVILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVS 181
PVV+LEGH+KRVGI+AWHPTARNVLLSAGCDN ++IWNVGT E L LD +H D+IYNVS
Sbjct: 124 PVVVLEGHTKRVGIIAWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNVS 183
Query: 182 WNRNGSLICTASKDKKVRVIDPRKQEIVAEKEKAHEGARPMRAIFLADGNVFTTGFSRMS 241
WN NGSL C+A KDK VR+IDPR+ +VAE+EKAHEGARPMRAIFLADG VFTTGFSRMS
Sbjct: 184 WNHNGSLFCSACKDKSVRIIDPRRGTLVAEREKAHEGARPMRAIFLADGKVFTTGFSRMS 243
Query: 242 ERQLALWNPKNMQEPIALHEMDTSNGVLLPFYDPDTSIIYLCGKGDSSIRYFEITDESPY 301
ERQLALW+P+N++EP+AL E+D+SNG LLPFYDPDTS++Y+CGKGDSSIRYFEIT+E PY
Sbjct: 244 ERQLALWDPENLEEPMALQELDSSNGALLPFYDPDTSVVYVCGKGDSSIRYFEITEEPPY 303
Query: 302 VHYLNTFSSKEPQRGMGYMPKRGLDVNKCEIARFFKLHERKCEPIIMTVPRKSDLFQDDL 361
+H+LNTF+SKEPQRGMG MPKRGL+V+KCEIARF+KLHERKCEPI+MTVPRKSDLFQDDL
Sbjct: 304 IHFLNTFTSKEPQRGMGSMPKRGLEVSKCEIARFYKLHERKCEPIVMTVPRKSDLFQDDL 363
Query: 362 YPDTAGPEAALEAEEWFEGKNADPILISLKHGYIPGKNRDLKVVKKNIL-DSKPTANKKC 420
YPDTAGPEAALEAEEW G++ADPILISL+ Y+P K RDLK+ ++N+L DS+P
Sbjct: 364 YPDTAGPEAALEAEEWVSGRDADPILISLREAYVPSKQRDLKISRRNVLSDSRPAMAPGS 423
Query: 421 DLISIPKKTTDTASVQ---------NEAKLDEILKEIKSIKDTICNQDERISKLEQQMAK 471
+ P TT A KL+E+++E+++++ + Q +RI +LE+Q+ +
Sbjct: 424 SHLGAPASTTTAADATPSGSLARAGEAGKLEEVMQELRALRALVKEQGDRICRLEEQLGR 483
Query: 472 I 472
+
Sbjct: 484 M 484
>gi|14149734 coronin, actin binding protein, 1B [Homo sapiens]
Length = 489
Score = 757 bits (1954), Expect = 0.0
Identities = 350/481 (72%), Positives = 415/481 (86%), Gaps = 10/481 (2%)
Query: 2 RRVVRQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSSFCAVNPRFVAIIIEASGGGAFLVL 61
R+VVRQSKFRHVFGQ VKNDQCY+DIRVSRVTWDS+FCAVNP+F+A+I+EASGGGAFLVL
Sbjct: 4 RKVVRQSKFRHVFGQPVKNDQCYEDIRVSRVTWDSTFCAVNPKFLAVIVEASGGGAFLVL 63
Query: 62 PLHKTGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTE 121
PL KTGRIDK+YPTVCGHTGPVLDIDWCPHND+VIASGSEDCTVMVWQIPENGLT LTE
Sbjct: 64 PLSKTGRIDKAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTE 123
Query: 122 PVVILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVS 181
PVV+LEGH+KRVGI+AWHPTARNVLLSAGCDN ++IWNVGT E L LD +H D+IYNVS
Sbjct: 124 PVVVLEGHTKRVGIIAWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNVS 183
Query: 182 WNRNGSLICTASKDKKVRVIDPRKQEIVAEKEKAHEGARPMRAIFLADGNVFTTGFSRMS 241
WN NGSL C+A KDK VR+IDPR+ +VAE+EKAHEGARPMRAIFLADG VFTTGFSRMS
Sbjct: 184 WNHNGSLFCSACKDKSVRIIDPRRGTLVAEREKAHEGARPMRAIFLADGKVFTTGFSRMS 243
Query: 242 ERQLALWNPKNMQEPIALHEMDTSNGVLLPFYDPDTSIIYLCGKGDSSIRYFEITDESPY 301
ERQLALW+P+N++EP+AL E+D+SNG LLPFYDPDTS++Y+CGKGDSSIRYFEIT+E PY
Sbjct: 244 ERQLALWDPENLEEPMALQELDSSNGALLPFYDPDTSVVYVCGKGDSSIRYFEITEEPPY 303
Query: 302 VHYLNTFSSKEPQRGMGYMPKRGLDVNKCEIARFFKLHERKCEPIIMTVPRKSDLFQDDL 361
+H+LNTF+SKEPQRGMG MPKRGL+V+KCEIARF+KLHERKCEPI+MTVPRKSDLFQDDL
Sbjct: 304 IHFLNTFTSKEPQRGMGSMPKRGLEVSKCEIARFYKLHERKCEPIVMTVPRKSDLFQDDL 363
Query: 362 YPDTAGPEAALEAEEWFEGKNADPILISLKHGYIPGKNRDLKVVKKNIL-DSKPTANKKC 420
YPDTAGPEAALEAEEW G++ADPILISL+ Y+P K RDLK+ ++N+L DS+P
Sbjct: 364 YPDTAGPEAALEAEEWVSGRDADPILISLREAYVPSKQRDLKISRRNVLSDSRPAMAPGS 423
Query: 421 DLISIPKKTTDTASVQ---------NEAKLDEILKEIKSIKDTICNQDERISKLEQQMAK 471
+ P TT A KL+E+++E+++++ + Q +RI +LE+Q+ +
Sbjct: 424 SHLGAPASTTTAADATPSGSLARAGEAGKLEEVMQELRALRALVKEQGDRICRLEEQLGR 483
Query: 472 I 472
+
Sbjct: 484 M 484
>gi|109627650 coronin 6 [Homo sapiens]
Length = 472
Score = 698 bits (1801), Expect = 0.0
Identities = 322/471 (68%), Positives = 397/471 (84%), Gaps = 6/471 (1%)
Query: 2 RRVVRQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSSFCAVNPRFVAIIIEASGGGAFLVL 61
RRVVRQSKFRHVFGQA K DQ Y+DIRVS+VTWDSSFCAVNP+F+AII+EA GGGAF+VL
Sbjct: 3 RRVVRQSKFRHVFGQAAKADQAYEDIRVSKVTWDSSFCAVNPKFLAIIVEAGGGGAFIVL 62
Query: 62 PLHKTGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTE 121
PL KTGR+DK+YP V GHT PVLDIDWCPHND VIAS S+D T+MVWQIP+ ++TE
Sbjct: 63 PLAKTGRVDKNYPLVTGHTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRNITE 122
Query: 122 PVVILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVS 181
P++ LEGHSKRVGI++WHPTARNVLLSAG DN IIIWNVGTGE L++LDDMH D+I++V
Sbjct: 123 PIITLEGHSKRVGILSWHPTARNVLLSAGGDNVIIIWNVGTGEVLLSLDDMHPDVIHSVC 182
Query: 182 WNRNGSLICTASKDKKVRVIDPRKQEIVAEKEKAHEGARPMRAIFLADGNVFTTGFSRMS 241
WN NGSL+ T KDK +R+IDPRK ++VAE+ AHEG RPMRA+F G++FTTGF+RMS
Sbjct: 183 WNSNGSLLATTCKDKTLRIIDPRKGQVVAERFAAHEGMRPMRAVFTRQGHIFTTGFTRMS 242
Query: 242 ERQLALWNPKNMQEPIALHEMDTSNGVLLPFYDPDTSIIYLCGKGDSSIRYFEITDESPY 301
+R+L LW+P N +EP+AL EMDTSNGVLLPFYDPD+SI+YLCGKGDSSIRYFEITDE P+
Sbjct: 243 QRELGLWDPNNFEEPVALQEMDTSNGVLLPFYDPDSSIVYLCGKGDSSIRYFEITDEPPF 302
Query: 302 VHYLNTFSSKEPQRGMGYMPKRGLDVNKCEIARFFKLHERKCEPIIMTVPRKSDLFQDDL 361
VHYLNTFSSKEPQRGMG+MPKRGLDV+KCEIARF+KLHERKCEPIIMTVPRKSDLFQDDL
Sbjct: 303 VHYLNTFSSKEPQRGMGFMPKRGLDVSKCEIARFYKLHERKCEPIIMTVPRKSDLFQDDL 362
Query: 362 YPDTAGPEAALEAEEWFEGKNADPILISLKHGYIPGKNRDLKVVKKNILDSKPTANKKCD 421
YPDT GPE ALEA+EW G++A+P+LISL+ GY+P K+R+L+V K+NILD +P + +
Sbjct: 363 YPDTPGPEPALEADEWLSGQDAEPVLISLRDGYVPPKHRELRVTKRNILDVRPPSGPR-- 420
Query: 422 LISIPKKTTDTASVQNEAKLDEILKEIKSIKDTICNQDERISKLEQQMAKI 472
++ A + + L+ +L+EIK++++ + Q++RI+ LE + ++
Sbjct: 421 ----RSQSASDAPLSQQHTLETLLEEIKALRERVQAQEQRITALENMLCEL 467
>gi|5902134 coronin, actin binding protein, 1A [Homo sapiens]
Length = 461
Score = 645 bits (1663), Expect = 0.0
Identities = 302/467 (64%), Positives = 383/467 (82%), Gaps = 14/467 (2%)
Query: 2 RRVVRQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSSFCAVNPRFVAIIIEASGGGAFLVL 61
R+VVR SKFRHVFGQ K DQCY+D+RVS+ TWDS FCAVNP+FVA+I EASGGGAFLVL
Sbjct: 3 RQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAFLVL 62
Query: 62 PLHKTGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTE 121
PL KTGR+DK+ PTVCGHT PVLDI WCPHND VIASGSEDCTVMVW+IP+ GL L L E
Sbjct: 63 PLGKTGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPLRE 122
Query: 122 PVVILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLD-DMHSDMIYNV 180
PVV LEGH+KRVGIVAWH TA+NVLLSAGCDN I++W+VGTG A++ L ++H D IY+V
Sbjct: 123 PVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIYSV 182
Query: 181 SWNRNGSLICTASKDKKVRVIDPRKQEIVAEKEKAHEGARPMRAIFLADGNVFTTGFSRM 240
W+R+G LICT+ +DK+VR+I+PRK +VAEK++ HEG RP+RA+F+++G + TTGFSRM
Sbjct: 183 DWSRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGFSRM 242
Query: 241 SERQLALWNPKNMQEPIALHEMDTSNGVLLPFYDPDTSIIYLCGKGDSSIRYFEITDESP 300
SERQ+ALW+ K+++EP++L E+DTS+GVLLPF+DPDT+I+YLCGKGDSSIRYFEIT E+P
Sbjct: 243 SERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSEAP 302
Query: 301 YVHYLNTFSSKEPQRGMGYMPKRGLDVNKCEIARFFKLHERKCEPIIMTVPRKSDLFQDD 360
++HYL+ FSSKE QRGMGYMPKRGL+VNKCEIARF+KLHER+CEPI MTVPRKSDLFQ+D
Sbjct: 303 FLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERRCEPIAMTVPRKSDLFQED 362
Query: 361 LYPDTAGPEAALEAEEWFEGKNADPILISLKHGYIPGKNRDLKVVKKNILDSKPTANKKC 420
LYP TAGP+ AL AEEW G++A P+LISLK GY+P K+R+L+V + T ++
Sbjct: 363 LYPPTAGPDPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNR-----GLDTGRRRA 417
Query: 421 DLISIPKKTTDTASVQNEAKLDEILKEIKSIKDTICNQDERISKLEQ 467
+ + T S ++L+E E++ ++ T+ +R+ +LE+
Sbjct: 418 -----APEASGTPSSDAVSRLEE---EMRKLQATVQELQKRLDRLEE 456
>gi|148529011 coronin, actin binding protein, 2B [Homo sapiens]
Length = 480
Score = 417 bits (1073), Expect = e-117
Identities = 215/472 (45%), Positives = 307/472 (65%), Gaps = 16/472 (3%)
Query: 6 RQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSSFCAVNPRFVAIIIEASGGGAFLVLPLHK 65
R SKFR+V+G+ + C+D I +++ D+ FCAVN RF+AI+ E++GGG+FLV+PL +
Sbjct: 13 RSSKFRNVYGKVANREHCFDGIPITKNVHDNHFCAVNTRFLAIVTESAGGGSFLVIPLEQ 72
Query: 66 TGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVI 125
TGRI+ +YP VCGH G VLDI W P D +IAS SED +V +W+IPE GL ++TE ++
Sbjct: 73 TGRIEPNYPKVCGHQGNVLDIKWNPFIDNIIASCSEDTSVRIWEIPEGGLKRNMTEALLE 132
Query: 126 LEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWNRN 185
L GHS+RVG+V WHPT N+L SAG D ++IWN+ GE + + D H+D+I +S+N +
Sbjct: 133 LHGHSRRVGLVEWHPTTNNILFSAGYDYKVLIWNLDVGEP-VKMIDCHTDVILCMSFNTD 191
Query: 186 GSLICTASKDKKVRVIDPRKQEIVAEKE-KAHEGARPMRAIFLAD-GNVFTTGFSRMSER 243
GSL+ T KDKK+RVI+PR ++ E K H R R +FL + + TTG SR + R
Sbjct: 192 GSLLTTTCKDKKLRVIEPRSGRVLQEANCKNH---RVNRVVFLGNMKRLLTTGVSRWNTR 248
Query: 244 QLALWNPKNMQEPIALHEMDTSNGVLLPFYDPDTSIIYLCGKGDSSIRYFEITDESPYVH 303
Q+ALW+ +++ P+ E+D +G+L PFYD DT ++YL GKGD +IRY+EI+ E PY+
Sbjct: 249 QIALWDQEDLSMPLIEEEIDGLSGLLFPFYDADTHMLYLAGKGDGNIRYYEISTEKPYLS 308
Query: 304 YLNTFSSKEPQRGMGYMPKRGLDVNKCEIARFFKLHERK--CEPIIMTVPRKSDLFQDDL 361
YL F S PQ+G+G MPK GLDV+ CE+ RF+KL K EPI M VPR+SD +Q+D+
Sbjct: 309 YLMEFRSPAPQKGLGVMPKHGLDVSACEVFRFYKLVTLKGLIEPISMIVPRRSDSYQEDI 368
Query: 362 YPDTAGPEAALEAEEWFEGKNADPILISLKHGYIPGKNRDLKVVKKNILDSKPTANKKCD 421
YP T G E AL +EW G N DP+L+SLK GY K V K I + K D
Sbjct: 369 YPMTPGTEPALTPDEWLGGINRDPVLMSLKEGY---KKSSKMVFKAPIKEKKSVVVNGID 425
Query: 422 LI-SIPKKTTDTASVQNEAKLDEILKEIKSIKDTICNQDERISKLEQQMAKI 472
L+ ++P +T + + D EI+ +K+ + +D RI +L+ ++ +
Sbjct: 426 LLENVPPRTENELLRMFFRQQD----EIRRLKEELAQKDIRIRQLQLELKNL 473
>gi|209529711 coronin, actin binding protein, 2A [Homo sapiens]
Length = 525
Score = 410 bits (1054), Expect = e-114
Identities = 195/395 (49%), Positives = 276/395 (69%), Gaps = 9/395 (2%)
Query: 6 RQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSSFCAVNPRFVAIIIEASGGGAFLVLPLHK 65
R SKFRHVFG+ + CYD + ++R D+ FCAVNP F+A++ E +GGGAFLV+PLH+
Sbjct: 8 RSSKFRHVFGKPASKENCYDSVPITRSVHDNHFCAVNPHFIAVVTECAGGGAFLVIPLHQ 67
Query: 66 TGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVI 125
TG++D YP VCGH G VLD+ W P +D IAS SED T+ +W IP+ LT +LT
Sbjct: 68 TGKLDPHYPKVCGHRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPKQLLTRNLTAYRKE 127
Query: 126 LEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALI----NLDDMHSDMIYNVS 181
L GH++RVG+V WHPTA N+L SAG D ++IWN+ T E++I + H D+I ++S
Sbjct: 128 LVGHARRVGLVEWHPTAANILFSAGYDYKVMIWNLDTKESVITSPMSTISCHQDVILSMS 187
Query: 182 WNRNGSLICTASKDKKVRVIDPRKQEIVAEKEKAHEGARPMRAIFLAD-GNVFTTGFSRM 240
+N NGSL+ T KD+K+RVIDPR ++ +E +++G R + +FL + + +TG SR
Sbjct: 188 FNTNGSLLATTCKDRKIRVIDPRAGTVL--QEASYKGHRASKVLFLGNLKKLMSTGTSRW 245
Query: 241 SERQLALWNPKNMQEPIALHEMDTSNGVLLPFYDPDTSIIYLCGKGDSSIRYFEITDESP 300
+ RQ+ALW+ N+ P+ ++D S+GVL PFYD DTS++Y+ GKGD +IRY+E++ + P
Sbjct: 246 NNRQVALWDQDNLSVPLMEEDLDGSSGVLFPFYDADTSMLYVVGKGDGNIRYYEVSADKP 305
Query: 301 YVHYLNTFSSKEPQRGMGYMPKRGLDVNKCEIARFFKLHERK--CEPIIMTVPRKSDLFQ 358
++ YL + S PQ+G+G MPKRGLDV+ CEI RF+KL K EPI M VPR+S+ +Q
Sbjct: 306 HLSYLTEYRSYNPQKGIGVMPKRGLDVSSCEIFRFYKLITTKSLIEPISMIVPRRSESYQ 365
Query: 359 DDLYPDTAGPEAALEAEEWFEGKNADPILISLKHG 393
+D+YP TAG + +L A+EW G N DPIL+SL+ G
Sbjct: 366 EDIYPPTAGAQPSLTAQEWLSGMNRDPILVSLRPG 400
>gi|16554585 coronin, actin binding protein, 2A [Homo sapiens]
Length = 525
Score = 410 bits (1054), Expect = e-114
Identities = 195/395 (49%), Positives = 276/395 (69%), Gaps = 9/395 (2%)
Query: 6 RQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSSFCAVNPRFVAIIIEASGGGAFLVLPLHK 65
R SKFRHVFG+ + CYD + ++R D+ FCAVNP F+A++ E +GGGAFLV+PLH+
Sbjct: 8 RSSKFRHVFGKPASKENCYDSVPITRSVHDNHFCAVNPHFIAVVTECAGGGAFLVIPLHQ 67
Query: 66 TGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVI 125
TG++D YP VCGH G VLD+ W P +D IAS SED T+ +W IP+ LT +LT
Sbjct: 68 TGKLDPHYPKVCGHRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPKQLLTRNLTAYRKE 127
Query: 126 LEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALI----NLDDMHSDMIYNVS 181
L GH++RVG+V WHPTA N+L SAG D ++IWN+ T E++I + H D+I ++S
Sbjct: 128 LVGHARRVGLVEWHPTAANILFSAGYDYKVMIWNLDTKESVITSPMSTISCHQDVILSMS 187
Query: 182 WNRNGSLICTASKDKKVRVIDPRKQEIVAEKEKAHEGARPMRAIFLAD-GNVFTTGFSRM 240
+N NGSL+ T KD+K+RVIDPR ++ +E +++G R + +FL + + +TG SR
Sbjct: 188 FNTNGSLLATTCKDRKIRVIDPRAGTVL--QEASYKGHRASKVLFLGNLKKLMSTGTSRW 245
Query: 241 SERQLALWNPKNMQEPIALHEMDTSNGVLLPFYDPDTSIIYLCGKGDSSIRYFEITDESP 300
+ RQ+ALW+ N+ P+ ++D S+GVL PFYD DTS++Y+ GKGD +IRY+E++ + P
Sbjct: 246 NNRQVALWDQDNLSVPLMEEDLDGSSGVLFPFYDADTSMLYVVGKGDGNIRYYEVSADKP 305
Query: 301 YVHYLNTFSSKEPQRGMGYMPKRGLDVNKCEIARFFKLHERK--CEPIIMTVPRKSDLFQ 358
++ YL + S PQ+G+G MPKRGLDV+ CEI RF+KL K EPI M VPR+S+ +Q
Sbjct: 306 HLSYLTEYRSYNPQKGIGVMPKRGLDVSSCEIFRFYKLITTKSLIEPISMIVPRRSESYQ 365
Query: 359 DDLYPDTAGPEAALEAEEWFEGKNADPILISLKHG 393
+D+YP TAG + +L A+EW G N DPIL+SL+ G
Sbjct: 366 EDIYPPTAGAQPSLTAQEWLSGMNRDPILVSLRPG 400
>gi|168229161 coronin 7 [Homo sapiens]
Length = 925
Score = 233 bits (595), Expect = 2e-61
Identities = 134/392 (34%), Positives = 213/392 (54%), Gaps = 12/392 (3%)
Query: 8 SKFRHVFGQAVKNDQCYDDIRVSRVTW---DSSFCAVNPRFVAIIIEASGGGAFLVLPLH 64
SKFRH G + D +++ +T FCA R ++ S GG VL L
Sbjct: 471 SKFRHAQGTVLHRDSHITNLKGLNLTTPGESDGFCANKLRVAVPLL--SSGGQVAVLELR 528
Query: 65 KTGRI-DKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPV 123
K GR+ D + PT+ + V D+ W P + +A ED + +W++P GL LT P
Sbjct: 529 KPGRLPDTALPTL-QNGAAVTDLAWDPFDPHRLAVAGEDARIRLWRVPAEGLEEVLTTPE 587
Query: 124 VILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWN 183
+L GH++++ + +HP A NVL S+ D + IW++ G + L H D I++++W+
Sbjct: 588 TVLTGHTEKICSLRFHPLAANVLASSSYDLTVRIWDLQAGADRLKLQG-HQDQIFSLAWS 646
Query: 184 RNGSLICTASKDKKVRVIDPRKQEIVAEKEKAHEGARPMRAIFLADGN-VFTTGFSRMSE 242
+G + T KD +VRV PR ++ +G R R +++ DG + +GF SE
Sbjct: 647 PDGQQLATVCKDGRVRVYRPRSGPEPLQEGPGPKGGRGARIVWVCDGRCLLVSGFDSQSE 706
Query: 243 RQLALWNPKNMQE-PIALHEMDTSNGVLLPFYDPDTSIIYLCGKGDSSIRYFEITDESPY 301
RQL L+ + + P+A+ +D + LLP YDPDT ++ L GKGD+ + +E+ ESP+
Sbjct: 707 RQLLLYEAEALAGGPLAVLGLDVAPSTLLPSYDPDTGLVLLTGKGDTRVFLYELLPESPF 766
Query: 302 VHYLNTFSSKEPQRGMGYMPKRGLDVNKCEIARFFKLHERKCEPIIMTVPR-KSDLFQDD 360
N+F+S +P +G+ +PK DV + E+ R +L + EP+ +PR + + FQDD
Sbjct: 767 FLECNSFTSPDPHKGLVLLPKTECDVREVELMRCLRLRQSSLEPVAFRLPRVRKEFFQDD 826
Query: 361 LYPDTAGP-EAALEAEEWFEGKNADPILISLK 391
++PDTA E L AE W +G N P L+SL+
Sbjct: 827 VFPDTAVIWEPVLSAEAWLQGANGQPWLLSLQ 858
Score = 203 bits (516), Expect = 3e-52
Identities = 118/386 (30%), Positives = 201/386 (52%), Gaps = 6/386 (1%)
Query: 6 RQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSSFCAVNPRFVAIIIEASGGGAFLVLPLHK 65
R SKFRH + + + DIR T S + I + G ++PL
Sbjct: 5 RVSKFRHTEARPPRRESWISDIRAG--TAPSCRNHIKSSCSLIAFNSDRPGVLGIVPLQG 62
Query: 66 TGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVI 125
G + + H+ V D+D+ P +D ++A+GS D TV +W++P G L + P V+
Sbjct: 63 QGEDKRRVAHLGCHSDLVTDLDFSPFDDFLLATGSADRTVKLWRLPGPGQALP-SAPGVV 121
Query: 126 LEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWNRN 185
L V ++ +HPT+ +L+SA + +W+ + L L H D++ + W+R+
Sbjct: 122 LGPEDLPVEVLQFHPTSDGILVSAA-GTTVKVWDAAKQQPLTELA-AHGDLVQSAVWSRD 179
Query: 186 GSLICTASKDKKVRVIDPRKQEIVAEKEKAHEGARPMRAIFLADG-NVFTTGFSRMSERQ 244
G+L+ TA KDK++R+ DPR + ++ +AHE +R R ++ ++ +TGF++M ER+
Sbjct: 180 GALVGTACKDKQLRIFDPRTKPRASQSTQAHENSRDSRLAWMGTWEHLVSTGFNQMRERE 239
Query: 245 LALWNPKNMQEPIALHEMDTSNGVLLPFYDPDTSIIYLCGKGDSSIRYFEITDESPYVHY 304
+ LW+ + +A +DTS G L+P DPD+ ++ L GKG+ + +E+ + P +
Sbjct: 240 VKLWDTRFFSSALASLTLDTSLGCLVPLLDPDSGLLVLAGKGERQLYCYEVVPQQPALSP 299
Query: 305 LNTFSSKEPQRGMGYMPKRGLDVNKCEIARFFKLHERKCEPIIMTVPRKSDLFQDDLYPD 364
+ + RG +P++ L V CE+ R +L + PI VPRK+ F +DL+PD
Sbjct: 300 VTQCVLESVLRGAALVPRQALAVMSCEVLRVLQLSDTAIVPIGYHVPRKAVEFHEDLFPD 359
Query: 365 TAGPEAALEAEEWFEGKNADPILISL 390
TAG A + W+ G N +SL
Sbjct: 360 TAGCVPATDPHSWWAGDNQQVQKVSL 385
>gi|20143912 WD repeat and SOCS box-containing 1 isoform 2 [Homo
sapiens]
Length = 275
Score = 70.9 bits (172), Expect = 2e-12
Identities = 60/242 (24%), Positives = 106/242 (43%), Gaps = 15/242 (6%)
Query: 69 IDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEG 128
I K + HT V D+ + P ++ S S D T+ VW + ++G + +L G
Sbjct: 13 IGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVWDLKDDGNMMK------VLRG 66
Query: 129 HSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWNRNGSL 188
H V A+ P + ++L S G A+ +WN+ + L+ H D++ ++ +G+L
Sbjct: 67 HQNWVYSCAFSPDS-SMLCSVGASKAVFLWNMDKYTMIRKLEGHHHDVV-ACDFSPDGAL 124
Query: 189 ICTASKDKKVRVIDPRKQEIVAEKEKAHEGARPMRAIFLADGNVFTTGFSRMSERQLALW 248
+ TAS D +V + DP +I+ E P+ A D V + FS +L
Sbjct: 125 LATASYDTRVYIWDPHNGDILMEFGHLFPPPTPIFAGGANDRWVRSVSFSHDGLHVASLA 184
Query: 249 NPK-----NMQEPIALHEMDTSNGVLLPFYDPDTSIIYLCGKGDSSIRYFEITDESPYVH 303
+ K + E + SNG+ F D S++ G D S+ ++ + P +
Sbjct: 185 DDKMVRFWRIDEDYPVQVAPLSNGLCCAF-STDGSVL-AAGTHDGSVYFWATPRQVPSLQ 242
Query: 304 YL 305
+L
Sbjct: 243 HL 244
>gi|18677720 WD repeat and SOCS box-containing 1 isoform 1 [Homo
sapiens]
Length = 421
Score = 70.5 bits (171), Expect = 3e-12
Identities = 58/232 (25%), Positives = 103/232 (44%), Gaps = 15/232 (6%)
Query: 79 HTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRVGIVAW 138
HT V D+ + P ++ S S D T+ VW + ++G + +L GH V A+
Sbjct: 169 HTEVVRDLTFAPDGSLILVSASRDKTLRVWDLKDDGNMMK------VLRGHQNWVYSCAF 222
Query: 139 HPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWNRNGSLICTASKDKKV 198
P + ++L S G A+ +WN+ + L+ H D++ ++ +G+L+ TAS D +V
Sbjct: 223 SPDS-SMLCSVGASKAVFLWNMDKYTMIRKLEGHHHDVV-ACDFSPDGALLATASYDTRV 280
Query: 199 RVIDPRKQEIVAEKEKAHEGARPMRAIFLADGNVFTTGFSRMSERQLALWNPK-----NM 253
+ DP +I+ E P+ A D V + FS +L + K +
Sbjct: 281 YIWDPHNGDILMEFGHLFPPPTPIFAGGANDRWVRSVSFSHDGLHVASLADDKMVRFWRI 340
Query: 254 QEPIALHEMDTSNGVLLPFYDPDTSIIYLCGKGDSSIRYFEITDESPYVHYL 305
E + SNG+ F D S++ G D S+ ++ + P + +L
Sbjct: 341 DEDYPVQVAPLSNGLCCAF-STDGSVL-AAGTHDGSVYFWATPRQVPSLQHL 390
Score = 47.0 bits (110), Expect = 4e-05
Identities = 30/158 (18%), Positives = 74/158 (46%), Gaps = 12/158 (7%)
Query: 95 VIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRVGIVAWHPTARNVLLSAGCDNA 154
++A+G + + +W + L L+L + H++ V + + P +L+SA D
Sbjct: 142 LLATGLNNGRIKIWDVYTGKLLLNLVD-------HTEVVRDLTFAPDGSLILVSASRDKT 194
Query: 155 IIIWNVGTGEALINLDDMHSDMIYNVSWNRNGSLICTASKDKKVRVIDPRKQEIVAEKEK 214
+ +W++ ++ + H + +Y+ +++ + S++C+ K V + + K ++ + E
Sbjct: 195 LRVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKLEG 254
Query: 215 AHEGARPMRAIFLADGNVFTTGFSRMSERQLALWNPKN 252
H + F DG + T + ++ +W+P N
Sbjct: 255 HHHDV--VACDFSPDGALLATA---SYDTRVYIWDPHN 287
>gi|207029439 retinoblastoma binding protein 4 isoform c [Homo
sapiens]
Length = 390
Score = 68.9 bits (167), Expect = 9e-12
Identities = 49/233 (21%), Positives = 104/233 (44%), Gaps = 18/233 (7%)
Query: 22 QCYDDIRVSRVTWDSSFCAVNPRFVAIIIEASGGGAFLVLPLH---KTGRIDKSYPTVCG 78
+C D+R+ + + NP ++ AS + + K G++ + G
Sbjct: 131 ECNPDLRLRGHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTG 190
Query: 79 HTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRVGIVAW 138
HT V D+ W ++ + S ++D +M+W N + ++P ++ H+ V +++
Sbjct: 191 HTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSN----NTSKPSHSVDAHTAEVNCLSF 246
Query: 139 HPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWN-RNGSLICTASKDKK 197
+P + +L + D + +W++ + ++ + H D I+ V W+ N +++ ++ D++
Sbjct: 247 NPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRR 306
Query: 198 VRVIDPRKQEIVAEKEKAHEGARPMRAIFLADGNVFTTGFSRMSERQLALWNP 250
+ V D K E A +G P +F+ G+ T S S WNP
Sbjct: 307 LNVWDLSKIGEEQSPEDAEDG--PPELLFIHGGH--TAKISDFS------WNP 349
Score = 47.4 bits (111), Expect = 3e-05
Identities = 26/100 (26%), Positives = 46/100 (46%), Gaps = 9/100 (9%)
Query: 79 HTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLT-------EPVVILEGHSK 131
H + + W PHN+ ++AS D + VW + + G S E + I GH+
Sbjct: 281 HKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPELLFIHGGHTA 340
Query: 132 RVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDD 171
++ +W+P V+ S DN + +W + E + N +D
Sbjct: 341 KISDFSWNPNEPWVICSVSEDNIMQVWQM--AENIYNDED 378
Score = 39.3 bits (90), Expect = 0.008
Identities = 17/36 (47%), Positives = 21/36 (58%)
Query: 78 GHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPEN 113
GHT + D W P+ VI S SED + VWQ+ EN
Sbjct: 337 GHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAEN 372
>gi|207029415 retinoblastoma binding protein 4 isoform b [Homo
sapiens]
Length = 424
Score = 68.9 bits (167), Expect = 9e-12
Identities = 49/233 (21%), Positives = 104/233 (44%), Gaps = 18/233 (7%)
Query: 22 QCYDDIRVSRVTWDSSFCAVNPRFVAIIIEASGGGAFLVLPLH---KTGRIDKSYPTVCG 78
+C D+R+ + + NP ++ AS + + K G++ + G
Sbjct: 165 ECNPDLRLRGHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTG 224
Query: 79 HTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRVGIVAW 138
HT V D+ W ++ + S ++D +M+W N + ++P ++ H+ V +++
Sbjct: 225 HTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSN----NTSKPSHSVDAHTAEVNCLSF 280
Query: 139 HPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWN-RNGSLICTASKDKK 197
+P + +L + D + +W++ + ++ + H D I+ V W+ N +++ ++ D++
Sbjct: 281 NPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRR 340
Query: 198 VRVIDPRKQEIVAEKEKAHEGARPMRAIFLADGNVFTTGFSRMSERQLALWNP 250
+ V D K E A +G P +F+ G+ T S S WNP
Sbjct: 341 LNVWDLSKIGEEQSPEDAEDG--PPELLFIHGGH--TAKISDFS------WNP 383
Score = 47.4 bits (111), Expect = 3e-05
Identities = 26/100 (26%), Positives = 46/100 (46%), Gaps = 9/100 (9%)
Query: 79 HTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLT-------EPVVILEGHSK 131
H + + W PHN+ ++AS D + VW + + G S E + I GH+
Sbjct: 315 HKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPELLFIHGGHTA 374
Query: 132 RVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDD 171
++ +W+P V+ S DN + +W + E + N +D
Sbjct: 375 KISDFSWNPNEPWVICSVSEDNIMQVWQM--AENIYNDED 412
Score = 39.3 bits (90), Expect = 0.008
Identities = 17/36 (47%), Positives = 21/36 (58%)
Query: 78 GHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPEN 113
GHT + D W P+ VI S SED + VWQ+ EN
Sbjct: 371 GHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAEN 406
>gi|5032027 retinoblastoma binding protein 4 isoform a [Homo
sapiens]
Length = 425
Score = 68.9 bits (167), Expect = 9e-12
Identities = 49/233 (21%), Positives = 104/233 (44%), Gaps = 18/233 (7%)
Query: 22 QCYDDIRVSRVTWDSSFCAVNPRFVAIIIEASGGGAFLVLPLH---KTGRIDKSYPTVCG 78
+C D+R+ + + NP ++ AS + + K G++ + G
Sbjct: 166 ECNPDLRLRGHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTG 225
Query: 79 HTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRVGIVAW 138
HT V D+ W ++ + S ++D +M+W N + ++P ++ H+ V +++
Sbjct: 226 HTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSN----NTSKPSHSVDAHTAEVNCLSF 281
Query: 139 HPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWN-RNGSLICTASKDKK 197
+P + +L + D + +W++ + ++ + H D I+ V W+ N +++ ++ D++
Sbjct: 282 NPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRR 341
Query: 198 VRVIDPRKQEIVAEKEKAHEGARPMRAIFLADGNVFTTGFSRMSERQLALWNP 250
+ V D K E A +G P +F+ G+ T S S WNP
Sbjct: 342 LNVWDLSKIGEEQSPEDAEDG--PPELLFIHGGH--TAKISDFS------WNP 384
Score = 47.4 bits (111), Expect = 3e-05
Identities = 26/100 (26%), Positives = 46/100 (46%), Gaps = 9/100 (9%)
Query: 79 HTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLT-------EPVVILEGHSK 131
H + + W PHN+ ++AS D + VW + + G S E + I GH+
Sbjct: 316 HKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPELLFIHGGHTA 375
Query: 132 RVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDD 171
++ +W+P V+ S DN + +W + E + N +D
Sbjct: 376 KISDFSWNPNEPWVICSVSEDNIMQVWQM--AENIYNDED 413
Score = 39.3 bits (90), Expect = 0.008
Identities = 17/36 (47%), Positives = 21/36 (58%)
Query: 78 GHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPEN 113
GHT + D W P+ VI S SED + VWQ+ EN
Sbjct: 372 GHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAEN 407
>gi|4506439 retinoblastoma binding protein 7 [Homo sapiens]
Length = 425
Score = 66.2 bits (160), Expect = 6e-11
Identities = 42/187 (22%), Positives = 89/187 (47%), Gaps = 15/187 (8%)
Query: 65 KTGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVV 124
K G+I + GH+ V D+ W ++ + S ++D +M+W N + ++P
Sbjct: 211 KEGKIVDAKAIFTGHSAVVEDVAWHLLHESLFGSVADDQKLMIWDTRSN----TTSKPSH 266
Query: 125 ILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWN- 183
+++ H+ V ++++P + +L + D + +W++ + ++ + H D I+ V W+
Sbjct: 267 LVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHTFESHKDEIFQVHWSP 326
Query: 184 RNGSLICTASKDKKVRVIDPRKQEIVAEKEKAHEGARPMRAIFLADGNVFTTGFSRMSER 243
N +++ ++ D+++ V D K E A +G P +F+ G+ T S S
Sbjct: 327 HNETILASSGTDRRLNVWDLSKIGEEQSAEDAEDG--PPELLFIHGGH--TAKISDFS-- 380
Query: 244 QLALWNP 250
WNP
Sbjct: 381 ----WNP 383
Score = 50.8 bits (120), Expect = 3e-06
Identities = 37/143 (25%), Positives = 62/143 (43%), Gaps = 3/143 (2%)
Query: 78 GHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRVGIVA 137
GH + W + + S S+D TV +W I + + I GHS V VA
Sbjct: 174 GHQKEGYGLSWNSNLSGHLLSASDDHTVCLWDINAGPKEGKIVDAKAIFTGHSAVVEDVA 233
Query: 138 WHPTARNVLLSAGCDNAIIIWNV--GTGEALINLDDMHSDMIYNVSWNRNGS-LICTASK 194
WH ++ S D ++IW+ T +L D H+ + +S+N ++ T S
Sbjct: 234 WHLLHESLFGSVADDQKLMIWDTRSNTTSKPSHLVDAHTAEVNCLSFNPYSEFILATGSA 293
Query: 195 DKKVRVIDPRKQEIVAEKEKAHE 217
DK V + D R ++ ++H+
Sbjct: 294 DKTVALWDLRNLKLKLHTFESHK 316
Score = 48.5 bits (114), Expect = 1e-05
Identities = 46/204 (22%), Positives = 87/204 (42%), Gaps = 29/204 (14%)
Query: 79 HTGPVLDIDWCPHNDQVIASGSEDCTVMVWQI---PENGLTLSLTEPVVILEGHSKRVGI 135
H G V + P N +IA+ + V+V+ P P + L GH K
Sbjct: 122 HEGEVNRARYMPQNPHIIATKTPSSDVLVFDYTKHPAKPDPSGECNPDLRLRGHQKEGYG 181
Query: 136 VAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDM------HSDMIYNVSWN-RNGSL 188
++W+ LLSA D+ + +W++ G + D HS ++ +V+W+ + SL
Sbjct: 182 LSWNSNLSGHLLSASDDHTVCLWDINAGPKEGKIVDAKAIFTGHSAVVEDVAWHLLHESL 241
Query: 189 ICTASKDKKVRVIDPR-----KQEIVAEKEKAHEGA---RPMRAIFLADGNVFTTGFSRM 240
+ + D+K+ + D R K + + A P LA G+
Sbjct: 242 FGSVADDQKLMIWDTRSNTTSKPSHLVDAHTAEVNCLSFNPYSEFILATGS--------- 292
Query: 241 SERQLALWNPKNMQEPIALHEMDT 264
+++ +ALW+ +N++ + LH ++
Sbjct: 293 ADKTVALWDLRNLK--LKLHTFES 314
Score = 47.8 bits (112), Expect = 2e-05
Identities = 24/89 (26%), Positives = 41/89 (46%), Gaps = 7/89 (7%)
Query: 79 HTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLT-------EPVVILEGHSK 131
H + + W PHN+ ++AS D + VW + + G S E + I GH+
Sbjct: 315 HKDEIFQVHWSPHNETILASSGTDRRLNVWDLSKIGEEQSAEDAEDGPPELLFIHGGHTA 374
Query: 132 RVGIVAWHPTARNVLLSAGCDNAIIIWNV 160
++ +W+P V+ S DN + IW +
Sbjct: 375 KISDFSWNPNEPWVICSVSEDNIMQIWQM 403
Score = 38.9 bits (89), Expect = 0.010
Identities = 16/36 (44%), Positives = 21/36 (58%)
Query: 78 GHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPEN 113
GHT + D W P+ VI S SED + +WQ+ EN
Sbjct: 371 GHTAKISDFSWNPNEPWVICSVSEDNIMQIWQMAEN 406
>gi|169403944 WD repeat domain 26 isoform b [Homo sapiens]
Length = 498
Score = 65.5 bits (158), Expect = 1e-10
Identities = 35/101 (34%), Positives = 56/101 (55%), Gaps = 6/101 (5%)
Query: 96 IASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRVGIVAWHPTARNVLLSAGCDNA- 154
+A+GS+D TV++WQ+ + L L + LEGH+ V +AW P N L++ G D+
Sbjct: 207 LATGSKDTTVIIWQVDPDTHLLKLLKT---LEGHAYGVSYIAWSPDD-NYLVACGPDDCS 262
Query: 155 -IIIWNVGTGEALINLDDMHSDMIYNVSWNRNGSLICTASK 194
+ +WNV TGE + H D + +V+WN +G T +
Sbjct: 263 ELWLWNVQTGELRTKMSQSHEDSLTSVAWNPDGKRFVTGGQ 303
Score = 48.1 bits (113), Expect = 2e-05
Identities = 24/68 (35%), Positives = 35/68 (51%), Gaps = 7/68 (10%)
Query: 91 HNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRVGIVAWHPTARNVLLSAG 150
HN+ IASGSED V +W P+ L GH++ V V+W+P +++ SA
Sbjct: 418 HNEDFIASGSEDHKVYIWHKRSE-------LPIAELTGHTRTVNCVSWNPQIPSMMASAS 470
Query: 151 CDNAIIIW 158
D + IW
Sbjct: 471 DDGTVRIW 478
Score = 35.4 bits (80), Expect = 0.11
Identities = 19/74 (25%), Positives = 35/74 (47%), Gaps = 7/74 (9%)
Query: 71 KSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCT-VMVWQIPENGLTLSLTEPVVILEGH 129
K T+ GH V I W P ++ ++A G +DC+ + +W + L ++ + H
Sbjct: 229 KLLKTLEGHAYGVSYIAWSPDDNYLVACGPDDCSELWLWNVQTGELRTKMS------QSH 282
Query: 130 SKRVGIVAWHPTAR 143
+ VAW+P +
Sbjct: 283 EDSLTSVAWNPDGK 296
Score = 33.5 bits (75), Expect = 0.43
Identities = 26/85 (30%), Positives = 35/85 (41%), Gaps = 7/85 (8%)
Query: 24 YDDIRVSRVTWDSSFCAVNPRFVAIIIEASGGGAFLVLPLHKTGRIDKSYPTVCGHTGPV 83
Y + T S F N F+A SG V HK R + + GHT V
Sbjct: 401 YQGVTQGFYTIHSCFGGHNEDFIA-----SGSEDHKVYIWHK--RSELPIAELTGHTRTV 453
Query: 84 LDIDWCPHNDQVIASGSEDCTVMVW 108
+ W P ++AS S+D TV +W
Sbjct: 454 NCVSWNPQIPSMMASASDDGTVRIW 478
>gi|55743153 WD repeat domain 26 isoform a [Homo sapiens]
Length = 514
Score = 65.5 bits (158), Expect = 1e-10
Identities = 35/101 (34%), Positives = 56/101 (55%), Gaps = 6/101 (5%)
Query: 96 IASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRVGIVAWHPTARNVLLSAGCDNA- 154
+A+GS+D TV++WQ+ + L L + LEGH+ V +AW P N L++ G D+
Sbjct: 223 LATGSKDTTVIIWQVDPDTHLLKLLKT---LEGHAYGVSYIAWSPDD-NYLVACGPDDCS 278
Query: 155 -IIIWNVGTGEALINLDDMHSDMIYNVSWNRNGSLICTASK 194
+ +WNV TGE + H D + +V+WN +G T +
Sbjct: 279 ELWLWNVQTGELRTKMSQSHEDSLTSVAWNPDGKRFVTGGQ 319
Score = 48.1 bits (113), Expect = 2e-05
Identities = 24/68 (35%), Positives = 35/68 (51%), Gaps = 7/68 (10%)
Query: 91 HNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRVGIVAWHPTARNVLLSAG 150
HN+ IASGSED V +W P+ L GH++ V V+W+P +++ SA
Sbjct: 434 HNEDFIASGSEDHKVYIWHKRSE-------LPIAELTGHTRTVNCVSWNPQIPSMMASAS 486
Query: 151 CDNAIIIW 158
D + IW
Sbjct: 487 DDGTVRIW 494
Score = 35.4 bits (80), Expect = 0.11
Identities = 19/74 (25%), Positives = 35/74 (47%), Gaps = 7/74 (9%)
Query: 71 KSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCT-VMVWQIPENGLTLSLTEPVVILEGH 129
K T+ GH V I W P ++ ++A G +DC+ + +W + L ++ + H
Sbjct: 245 KLLKTLEGHAYGVSYIAWSPDDNYLVACGPDDCSELWLWNVQTGELRTKMS------QSH 298
Query: 130 SKRVGIVAWHPTAR 143
+ VAW+P +
Sbjct: 299 EDSLTSVAWNPDGK 312
Score = 33.5 bits (75), Expect = 0.43
Identities = 26/85 (30%), Positives = 35/85 (41%), Gaps = 7/85 (8%)
Query: 24 YDDIRVSRVTWDSSFCAVNPRFVAIIIEASGGGAFLVLPLHKTGRIDKSYPTVCGHTGPV 83
Y + T S F N F+A SG V HK R + + GHT V
Sbjct: 417 YQGVTQGFYTIHSCFGGHNEDFIA-----SGSEDHKVYIWHK--RSELPIAELTGHTRTV 469
Query: 84 LDIDWCPHNDQVIASGSEDCTVMVW 108
+ W P ++AS S+D TV +W
Sbjct: 470 NCVSWNPQIPSMMASASDDGTVRIW 494
>gi|55743149 WD repeat domain 17 isoform 2 [Homo sapiens]
Length = 1298
Score = 64.3 bits (155), Expect = 2e-10
Identities = 38/128 (29%), Positives = 62/128 (48%), Gaps = 7/128 (5%)
Query: 79 HTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRVGIVAW 138
H V DW +N +IA+G ED V V+ + S +P+ + GH+ +V V W
Sbjct: 496 HPAAVFGCDWSQNNKDMIATGCEDTNVRVYYV-----ATSSDQPLKVFSGHTAKVFHVKW 550
Query: 139 HPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWNRN-GSLICTASKDKK 197
P +L S D + IW+ T +A IN+ + H+ + + WN L+ + S D
Sbjct: 551 SPLREGILCSGSDDGTVRIWDY-TQDACINILNGHTAPVRGLMWNTEIPYLLISGSWDYT 609
Query: 198 VRVIDPRK 205
++V D R+
Sbjct: 610 IKVWDTRE 617
Score = 55.5 bits (132), Expect = 1e-07
Identities = 32/131 (24%), Positives = 57/131 (43%), Gaps = 7/131 (5%)
Query: 70 DKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGH 129
D+ GHT V + W P + ++ SGS+D TV +W ++ + IL GH
Sbjct: 532 DQPLKVFSGHTAKVFHVKWSPLREGILCSGSDDGTVRIWDYTQDAC-------INILNGH 584
Query: 130 SKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWNRNGSLI 189
+ V + W+ +L+S D I +W+ G + + D +D+ +
Sbjct: 585 TAPVRGLMWNTEIPYLLISGSWDYTIKVWDTREGTCVDTVYDHGADVYGLTCHPSRPFTM 644
Query: 190 CTASKDKKVRV 200
+ S+D VR+
Sbjct: 645 ASCSRDSTVRL 655
Score = 52.8 bits (125), Expect = 7e-07
Identities = 32/119 (26%), Positives = 56/119 (47%), Gaps = 8/119 (6%)
Query: 78 GHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRVGIVA 137
GH + D + P + ++A+ S D T+ VW I N LT T P G+ + ++
Sbjct: 367 GHVETIFDCKFKPDDPNLLATASFDGTIKVWDI--NTLTAVYTSP-----GNEGVIYSLS 419
Query: 138 WHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSW-NRNGSLICTASKD 195
W P N + N IWNV G+ + ++ ++ I+ ++W +++ I T S D
Sbjct: 420 WAPGGLNCIAGGTSRNGAFIWNVQKGKIIQRFNEHGTNGIFCIAWSHKDSKRIATCSSD 478
Score = 45.1 bits (105), Expect = 1e-04
Identities = 27/105 (25%), Positives = 44/105 (41%), Gaps = 8/105 (7%)
Query: 71 KSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHS 130
K + + H + I WCPHN + ASGS D V++W + E + + L+
Sbjct: 50 KLHAIMSEHKKTITAISWCPHNPDLFASGSTDNLVIIWNVAEQ-------KVIAKLDSTK 102
Query: 131 KRVGIVAWHPTARNVLLSAGCDNAIIIWNV-GTGEALINLDDMHS 174
++W A +V+ + IW + G +I D HS
Sbjct: 103 GIPASLSWCWNAEDVVAFVSHRGPLFIWTISGPDSGVIVHKDAHS 147
>gi|31317311 WD repeat domain 17 isoform 1 [Homo sapiens]
Length = 1322
Score = 64.3 bits (155), Expect = 2e-10
Identities = 38/128 (29%), Positives = 62/128 (48%), Gaps = 7/128 (5%)
Query: 79 HTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRVGIVAW 138
H V DW +N +IA+G ED V V+ + S +P+ + GH+ +V V W
Sbjct: 520 HPAAVFGCDWSQNNKDMIATGCEDTNVRVYYV-----ATSSDQPLKVFSGHTAKVFHVKW 574
Query: 139 HPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWNRN-GSLICTASKDKK 197
P +L S D + IW+ T +A IN+ + H+ + + WN L+ + S D
Sbjct: 575 SPLREGILCSGSDDGTVRIWDY-TQDACINILNGHTAPVRGLMWNTEIPYLLISGSWDYT 633
Query: 198 VRVIDPRK 205
++V D R+
Sbjct: 634 IKVWDTRE 641
Score = 55.5 bits (132), Expect = 1e-07
Identities = 32/131 (24%), Positives = 57/131 (43%), Gaps = 7/131 (5%)
Query: 70 DKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGH 129
D+ GHT V + W P + ++ SGS+D TV +W ++ + IL GH
Sbjct: 556 DQPLKVFSGHTAKVFHVKWSPLREGILCSGSDDGTVRIWDYTQDAC-------INILNGH 608
Query: 130 SKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWNRNGSLI 189
+ V + W+ +L+S D I +W+ G + + D +D+ +
Sbjct: 609 TAPVRGLMWNTEIPYLLISGSWDYTIKVWDTREGTCVDTVYDHGADVYGLTCHPSRPFTM 668
Query: 190 CTASKDKKVRV 200
+ S+D VR+
Sbjct: 669 ASCSRDSTVRL 679
Score = 52.8 bits (125), Expect = 7e-07
Identities = 32/119 (26%), Positives = 56/119 (47%), Gaps = 8/119 (6%)
Query: 78 GHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRVGIVA 137
GH + D + P + ++A+ S D T+ VW I N LT T P G+ + ++
Sbjct: 391 GHVETIFDCKFKPDDPNLLATASFDGTIKVWDI--NTLTAVYTSP-----GNEGVIYSLS 443
Query: 138 WHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSW-NRNGSLICTASKD 195
W P N + N IWNV G+ + ++ ++ I+ ++W +++ I T S D
Sbjct: 444 WAPGGLNCIAGGTSRNGAFIWNVQKGKIIQRFNEHGTNGIFCIAWSHKDSKRIATCSSD 502
Score = 45.1 bits (105), Expect = 1e-04
Identities = 27/105 (25%), Positives = 44/105 (41%), Gaps = 8/105 (7%)
Query: 71 KSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHS 130
K + + H + I WCPHN + ASGS D V++W + E + + L+
Sbjct: 74 KLHAIMSEHKKTITAISWCPHNPDLFASGSTDNLVIIWNVAEQ-------KVIAKLDSTK 126
Query: 131 KRVGIVAWHPTARNVLLSAGCDNAIIIWNV-GTGEALINLDDMHS 174
++W A +V+ + IW + G +I D HS
Sbjct: 127 GIPASLSWCWNAEDVVAFVSHRGPLFIWTISGPDSGVIVHKDAHS 171
>gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens]
Length = 1336
Score = 64.3 bits (155), Expect = 2e-10
Identities = 43/156 (27%), Positives = 67/156 (42%), Gaps = 39/156 (25%)
Query: 78 GHTGPVLDIDWCPHNDQVIASGSEDC-----------------------TVMVWQIPENG 114
GH V +DW P V+ SGS+D TVM ++ NG
Sbjct: 242 GHGADVKCVDWHPTKGLVV-SGSKDSQQPIKFWDPKTGQSLATLHAHKNTVMEVKLNLNG 300
Query: 115 ---LTLS------------LTEPVVILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWN 159
LT S L E + + GH K VAWHP + S G D +++ W+
Sbjct: 301 NWLLTASRDHLCKLFDIRNLKEELQVFRGHKKEATAVAWHPVHEGLFASGGSDGSLLFWH 360
Query: 160 VGTGEALINLDDMHSDMIYNVSWNRNGSLICTASKD 195
VG + + ++ H MI++++W+ G ++C+ S D
Sbjct: 361 VGVEKEVGGMEMAHEGMIWSLAWHPLGHILCSGSND 396
Score = 52.4 bits (124), Expect = 9e-07
Identities = 45/173 (26%), Positives = 74/173 (42%), Gaps = 15/173 (8%)
Query: 79 HTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRVGIVAW 138
H + + + P D A+ S+D TV +W IL GH V V W
Sbjct: 201 HKEAIREASFSP-TDNKFATCSDDGTVRIWDFLR-------CHEERILRGHGADVKCVDW 252
Query: 139 HPTARNVLLSAGCDNA--IIIWNVGTGEALINLDDMHSDMIYNVSWNRNGSLICTASKDK 196
HPT + +++S D+ I W+ TG++L L H + + V N NG+ + TAS+D
Sbjct: 253 HPT-KGLVVSGSKDSQQPIKFWDPKTGQSLATLH-AHKNTVMEVKLNLNGNWLLTASRDH 310
Query: 197 KVRVIDPRKQEIVAEKEKAHEGARPMRAIFLADGNVFTTGFSRMSERQLALWN 249
++ D R + + + H+ A +F +G S+ L W+
Sbjct: 311 LCKLFDIRNLKEELQVFRGHKKEATAVAWHPVHEGLFASG---GSDGSLLFWH 360
Score = 35.4 bits (80), Expect = 0.11
Identities = 37/180 (20%), Positives = 68/180 (37%), Gaps = 16/180 (8%)
Query: 82 PVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRVGIVAWHPT 141
PV + W P +++ +G+ +W NGLT + IL+ H V + W
Sbjct: 121 PVFVVRWTPEGRRLV-TGASSGEFTLW----NGLTFNFE---TILQAHDSPVRAMTWSHN 172
Query: 142 ARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWNRNGSLICTASKDKKVRVI 201
+L+A + W + + H + I S++ + T S D VR+
Sbjct: 173 DM-WMLTADHGGYVKYWQSNMNN--VKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIW 229
Query: 202 DPRKQEIVAEKEKAHEG-ARPMRAIFLADGNVFTTGFSRMSERQLALWNPKNMQEPIALH 260
D + +E+ G ++ + S+ S++ + W+PK Q LH
Sbjct: 230 DFLR----CHEERILRGHGADVKCVDWHPTKGLVVSGSKDSQQPIKFWDPKTGQSLATLH 285
>gi|4885105 chromatin assembly factor 1 subunit B [Homo sapiens]
Length = 559
Score = 61.6 bits (148), Expect = 1e-09
Identities = 41/154 (26%), Positives = 71/154 (46%), Gaps = 17/154 (11%)
Query: 79 HTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPEN--------------GLTLSLTEPVV 124
HT V + + P +++ASG +D +++W++ +N L V
Sbjct: 65 HTKAVNVVRFSP-TGEILASGGDDAVILLWKVNDNKEPEQIAFQDEDEAQLNKENWTVVK 123
Query: 125 ILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWNR 184
L GH + V + W T N++ SA DN IIW+V G+ I++ + H + V+W+
Sbjct: 124 TLRGHLEDVYDICW-ATDGNLMASASVDNTAIIWDVSKGQK-ISIFNEHKSYVQGVTWDP 181
Query: 185 NGSLICTASKDKKVRVIDPRKQEIVAEKEKAHEG 218
G + T S D+ +RV +K+ + K G
Sbjct: 182 LGQYVATLSCDRVLRVYSIQKKRVAFNVSKMLSG 215
Score = 49.7 bits (117), Expect = 6e-06
Identities = 33/135 (24%), Positives = 62/135 (45%), Gaps = 21/135 (15%)
Query: 96 IASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRVGIVAWHPTARNVLLSAGCDNAI 155
+AS D V +W++ + ++ E + L H+K V +V + PT +L S G D I
Sbjct: 32 LASAGVDTNVRIWKVEKGPDGKAIVEFLSNLARHTKAVNVVRFSPTG-EILASGGDDAVI 90
Query: 156 IIWNVGTG------------EALINLDDM--------HSDMIYNVSWNRNGSLICTASKD 195
++W V EA +N ++ H + +Y++ W +G+L+ +AS D
Sbjct: 91 LLWKVNDNKEPEQIAFQDEDEAQLNKENWTVVKTLRGHLEDVYDICWATDGNLMASASVD 150
Query: 196 KKVRVIDPRKQEIVA 210
+ D K + ++
Sbjct: 151 NTAIIWDVSKGQKIS 165
>gi|4505731 peroxisomal biogenesis factor 7 [Homo sapiens]
Length = 323
Score = 61.2 bits (147), Expect = 2e-09
Identities = 29/126 (23%), Positives = 64/126 (50%), Gaps = 7/126 (5%)
Query: 79 HTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRVGIVAW 138
H +L DWC +N+ ++ +G+ DC++ W + ++ +PV L GH+ + V +
Sbjct: 197 HQAEILSCDWCKYNENLLVTGAVDCSLRGWDL------RNVRQPVFELLGHTYAIRRVKF 250
Query: 139 HPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWN-RNGSLICTASKDKK 197
P +VL S D + WN ++L+ + H++ + ++ ++ + + S D+
Sbjct: 251 SPFHASVLASCSYDFTVRFWNFSKPDSLLETVEHHTEFTCGLDFSLQSPTQVADCSWDET 310
Query: 198 VRVIDP 203
+++ DP
Sbjct: 311 IKIYDP 316
Score = 50.1 bits (118), Expect = 4e-06
Identities = 48/208 (23%), Positives = 93/208 (44%), Gaps = 18/208 (8%)
Query: 53 SGGGAFLVLPLHKTG-RIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIP 111
+G G L+L + G R+ +S+ G + D+ W +N+ V+ + S D ++ +W
Sbjct: 43 AGCGTLLILDPDEAGLRLFRSFDWNDG----LFDVTWSENNEHVLITCSGDGSLQLWD-- 96
Query: 112 ENGLTLSLTEPVVILEGHSKRVGIVAWHPT-ARNVLLSAGCDNAIIIWNVGTGEALINLD 170
T P+ + + H++ V V W T +++S D + +W+ G++L
Sbjct: 97 ----TAKAAGPLQVYKEHAQEVYSVDWSQTRGEQLVVSGSWDQTVKLWDPTVGKSLCTFR 152
Query: 171 DMHSDMIYNVSWNRN-GSLICTASKDKKVRVIDPRKQEIVAEKEKAHEGARPMRAIFLAD 229
H +IY+ W+ + +AS D+ +R+ D K V AH+ +
Sbjct: 153 G-HESIIYSTIWSPHIPGCFASASGDQTLRIWDV-KAAGVRIVIPAHQAEILSCDWCKYN 210
Query: 230 GNVFTTGFSRMSERQLALWNPKNMQEPI 257
N+ TG S R W+ +N+++P+
Sbjct: 211 ENLLVTGAVDCSLRG---WDLRNVRQPV 235
>gi|19913371 transducin (beta)-like 1 X-linked receptor 1 [Homo
sapiens]
Length = 514
Score = 60.1 bits (144), Expect = 4e-09
Identities = 49/194 (25%), Positives = 86/194 (44%), Gaps = 30/194 (15%)
Query: 66 TGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVI 125
TG + +P H+ P LD+DW +N AS S D + V ++ ++ P+
Sbjct: 297 TGEAKQQFPF---HSAPALDVDWQSNN--TFASCSTDMCIHVCKLGQD-------RPIKT 344
Query: 126 LEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWNRN 185
+GH+ V + W PT N+L S D + IW++ + +L H+ IY + W+
Sbjct: 345 FQGHTNEVNAIKWDPTG-NLLASCSDDMTLKIWSMKQDNCVHDL-QAHNKEIYTIKWSPT 402
Query: 186 GS---------LICTASKDKKVRVIDPRKQEIVAEKEKAHEGARPMRAI-FLADGNVFTT 235
G ++ +AS D VR+ D + + K E P+ ++ F DG +
Sbjct: 403 GPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQE---PVYSVAFSPDGRYLAS 459
Query: 236 GFSRMSERQLALWN 249
G ++ + +WN
Sbjct: 460 G---SFDKCVHIWN 470
Score = 48.5 bits (114), Expect = 1e-05
Identities = 37/116 (31%), Positives = 56/116 (48%), Gaps = 10/116 (8%)
Query: 90 PHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRVGIVAWHPTARNVLLSA 149
P+ + ++AS S D TV +W + +LT+ H + V VA+ P R L S
Sbjct: 409 PNANLMLASASFDSTVRLWDVDRGICIHTLTK-------HQEPVYSVAFSPDGR-YLASG 460
Query: 150 GCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWNRNGSLICTASKDKKVRVIDPRK 205
D + IWN TG AL++ + I+ V WN G + ++ D V V+D RK
Sbjct: 461 SFDKCVHIWNTQTG-ALVH-SYRGTGGIFEVCWNAAGDKVGASASDGSVCVLDLRK 514
Score = 46.2 bits (108), Expect = 6e-05
Identities = 42/139 (30%), Positives = 61/139 (43%), Gaps = 15/139 (10%)
Query: 78 GHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVV---ILEG-----H 129
GH V W P +D ++ASGS D T +W + EN T T+ V+ I EG
Sbjct: 167 GHESEVFICAWNPVSD-LLASGSGDSTARIWNLSENS-TSGSTQLVLRHCIREGGQDVPS 224
Query: 130 SKRVGIVAWHPTARNVLLSAGC-DNAIIIWNVGTGEALINLDDMHSDMIYNVSWNRNGSL 188
+K V + W+ + LL+ G D IW L + H I+ + WN+ G+
Sbjct: 225 NKDVTSLDWN--SEGTLLATGSYDGFARIWTKDGN--LASTLGQHKGPIFALKWNKKGNF 280
Query: 189 ICTASKDKKVRVIDPRKQE 207
I +A DK + D E
Sbjct: 281 ILSAGVDKTTIIWDAHTGE 299
Score = 45.8 bits (107), Expect = 8e-05
Identities = 55/258 (21%), Positives = 99/258 (38%), Gaps = 52/258 (20%)
Query: 83 VLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRVGIVAWHPTA 142
V +DW ++A+GS D +W N L+ T L H + + W+
Sbjct: 228 VTSLDWNSEGT-LLATGSYDGFARIWTKDGN---LAST-----LGQHKGPIFALKWNKKG 278
Query: 143 RNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWNRNGSL----------ICTA 192
N +LSAG D IIW+ TGEA HS +V W N + +C
Sbjct: 279 -NFILSAGVDKTTIIWDAHTGEAKQQF-PFHSAPALDVDWQSNNTFASCSTDMCIHVCKL 336
Query: 193 SKDKKVRVIDPRKQEIVAEKEKAHEGARPMRAIFLADGNVFTTGFSRMSERQLALWNPKN 252
+D+ ++ E+ A K + GN+ S + L +W +
Sbjct: 337 GQDRPIKTFQGHTNEVNAIK-------------WDPTGNLLA---SCSDDMTLKIW---S 377
Query: 253 MQEPIALHEMDTSNGVLLPF---------YDPDTSIIYLCGKGDSSIRYFEITDESPYVH 303
M++ +H++ N + +P+ +++ DS++R +++ D +H
Sbjct: 378 MKQDNCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWDV-DRGICIH 436
Query: 304 YLNTFSSKEPQRGMGYMP 321
L +EP + + P
Sbjct: 437 TLT--KHQEPVYSVAFSP 452
Score = 39.7 bits (91), Expect = 0.006
Identities = 27/90 (30%), Positives = 44/90 (48%), Gaps = 14/90 (15%)
Query: 124 VILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVG----TGEALINL--------DD 171
V+L GH V I AW+P + ++L S D+ IWN+ +G + L D
Sbjct: 163 VVLRGHESEVFICAWNPVS-DLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQD 221
Query: 172 MHSDM-IYNVSWNRNGSLICTASKDKKVRV 200
+ S+ + ++ WN G+L+ T S D R+
Sbjct: 222 VPSNKDVTSLDWNSEGTLLATGSYDGFARI 251
>gi|113865883 WD repeat domain 38 [Homo sapiens]
Length = 314
Score = 59.7 bits (143), Expect = 6e-09
Identities = 39/127 (30%), Positives = 67/127 (52%), Gaps = 10/127 (7%)
Query: 78 GHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRVGIVA 137
GHTGPV + P + + AS S DCTV +W + + + + +L+GH + V V+
Sbjct: 61 GHTGPVKFCRFSP-DGHLFASASCDCTVRLWDV-------ARAKCLRVLKGHQRSVETVS 112
Query: 138 WHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWNRNGSLICTASKDKK 197
+ P +R L S G D +++W+V +G+ ++ L H D I + ++ + + T S D
Sbjct: 113 FSPDSRQ-LASGGWDKRVMLWDVQSGQ-MLRLLVGHRDSIQSSDFSPTVNCLATGSWDST 170
Query: 198 VRVIDPR 204
V + D R
Sbjct: 171 VHIWDLR 177
Score = 40.8 bits (94), Expect = 0.003
Identities = 32/130 (24%), Positives = 63/130 (48%), Gaps = 11/130 (8%)
Query: 72 SYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSK 131
S+ + GH+ + + C ++ASGS D T+ +W+ + L ++ L+GH
Sbjct: 184 SHQALEGHSANISCL--CYSASGLLASGSWDKTIHIWKPTTSSL-------LIQLKGHVT 234
Query: 132 RVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWNRNGSLICT 191
V +A+ P L SAG + +W+ TG+ L L + D+ + ++ +G ++ +
Sbjct: 235 WVKSIAFSPD-ELWLASAGYSRMVKVWDCNTGKCLETLKGV-LDVAHTCAFTPDGKILVS 292
Query: 192 ASKDKKVRVI 201
+ D+ R I
Sbjct: 293 GAADQTRRQI 302
>gi|213021190 transducin beta-like 1X isoform b [Homo sapiens]
Length = 526
Score = 59.3 bits (142), Expect = 7e-09
Identities = 41/150 (27%), Positives = 74/150 (49%), Gaps = 21/150 (14%)
Query: 70 DKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVI--LE 127
D+ T GHT V I W P + ++AS S+D T+ +W S+ + V I L+
Sbjct: 351 DRPVKTFQGHTNEVNAIKWDP-SGMLLASCSDDMTLKIW---------SMKQEVCIHDLQ 400
Query: 128 GHSKRVGIVAWHPTA-------RNVLL-SAGCDNAIIIWNVGTGEALINLDDMHSDMIYN 179
H+K + + W PT N++L SA D+ + +W++ G L H + +Y+
Sbjct: 401 AHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTL-TKHQEPVYS 459
Query: 180 VSWNRNGSLICTASKDKKVRVIDPRKQEIV 209
V+++ +G + + S DK V + + + +V
Sbjct: 460 VAFSPDGKYLASGSFDKCVHIWNTQSGNLV 489
Score = 50.1 bits (118), Expect = 4e-06
Identities = 35/116 (30%), Positives = 55/116 (47%), Gaps = 10/116 (8%)
Query: 90 PHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRVGIVAWHPTARNVLLSA 149
P+++ ++AS S D TV +W I T +LT+ H + V VA+ P + L S
Sbjct: 421 PNSNIMLASASFDSTVRLWDIERGVCTHTLTK-------HQEPVYSVAFSPDGK-YLASG 472
Query: 150 GCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWNRNGSLICTASKDKKVRVIDPRK 205
D + IWN +G + + I+ V WN G + ++ D V V+D RK
Sbjct: 473 SFDKCVHIWNTQSGNLVHSYRGTGG--IFEVCWNARGDKVGASASDGSVCVLDLRK 526
Score = 48.1 bits (113), Expect = 2e-05
Identities = 40/137 (29%), Positives = 58/137 (42%), Gaps = 11/137 (8%)
Query: 78 GHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPEN---GLTLSLTEPVVILEGH----S 130
GH V W P +D ++ASGS D T +W + EN G T + + GH +
Sbjct: 179 GHESEVFICAWNPVSD-LLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSN 237
Query: 131 KRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWNRNGSLIC 190
K V + W+ T +L + D IW L + H I+ + WNR G+ I
Sbjct: 238 KDVTSLDWN-TNGTLLATGSYDGFARIWTEDGN--LASTLGQHKGPIFALKWNRKGNYIL 294
Query: 191 TASKDKKVRVIDPRKQE 207
+A DK + D E
Sbjct: 295 SAGVDKTTIIWDAHTGE 311
Score = 47.4 bits (111), Expect = 3e-05
Identities = 61/267 (22%), Positives = 102/267 (38%), Gaps = 56/267 (20%)
Query: 78 GHTGP----VLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRV 133
GH P V +DW N ++A+GS D +W E+G S L H +
Sbjct: 231 GHDVPSNKDVTSLDWNT-NGTLLATGSYDGFARIWT--EDGNLAST------LGQHKGPI 281
Query: 134 GIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWNRNGSL----- 188
+ W+ N +LSAG D IIW+ TGEA HS +V W N +
Sbjct: 282 FALKWNRKG-NYILSAGVDKTTIIWDAHTGEAKQQF-PFHSAPALDVDWQNNTTFASCST 339
Query: 189 -----ICTASKDKKVRVIDPRKQEIVAEKEKAHEGARPMRAIFLADGNVFTTGFSRMSER 243
+C D+ V+ E+ A K + LA S +
Sbjct: 340 DMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDP-------SGMLLA---------SCSDDM 383
Query: 244 QLALWNPKNMQEPIALHEMDTSNGVLLPF---------YDPDTSIIYLCGKGDSSIRYFE 294
L +W +M++ + +H++ N + +P+++I+ DS++R ++
Sbjct: 384 TLKIW---SMKQEVCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWD 440
Query: 295 ITDESPYVHYLNTFSSKEPQRGMGYMP 321
I + H L +EP + + P
Sbjct: 441 I-ERGVCTHTLT--KHQEPVYSVAFSP 464
Score = 43.5 bits (101), Expect = 4e-04
Identities = 48/222 (21%), Positives = 86/222 (38%), Gaps = 53/222 (23%)
Query: 75 TVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVW---------QIP-----------ENG 114
T+ H GP+ + W + ++++G D T ++W Q P +N
Sbjct: 273 TLGQHKGPIFALKWNRKGNYILSAG-VDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNN 331
Query: 115 LT--------------LSLTEPVVILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNV 160
T L PV +GH+ V + W P+ +L S D + IW++
Sbjct: 332 TTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGM-LLASCSDDMTLKIWSM 390
Query: 161 GTGEALINLDDMHSDMIYNVSWNRNGS---------LICTASKDKKVRVIDPRKQEIVAE 211
E I+ H+ IY + W+ G ++ +AS D VR+ D +
Sbjct: 391 -KQEVCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHT 449
Query: 212 KEKAHEGARPMRAI-FLADGNVFTTGFSRMSERQLALWNPKN 252
K E P+ ++ F DG +G ++ + +WN ++
Sbjct: 450 LTKHQE---PVYSVAFSPDGKYLASG---SFDKCVHIWNTQS 485
Score = 39.3 bits (90), Expect = 0.008
Identities = 26/89 (29%), Positives = 41/89 (46%), Gaps = 14/89 (15%)
Query: 125 ILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNV-----GTGEALI--------NLDD 171
+L GH V I AW+P + ++L S D+ IWN+ G L+ D
Sbjct: 176 VLRGHESEVFICAWNPVS-DLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDV 234
Query: 172 MHSDMIYNVSWNRNGSLICTASKDKKVRV 200
+ + ++ WN NG+L+ T S D R+
Sbjct: 235 PSNKDVTSLDWNTNGTLLATGSYDGFARI 263
>gi|213021188 transducin beta-like 1X isoform b [Homo sapiens]
Length = 526
Score = 59.3 bits (142), Expect = 7e-09
Identities = 41/150 (27%), Positives = 74/150 (49%), Gaps = 21/150 (14%)
Query: 70 DKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVI--LE 127
D+ T GHT V I W P + ++AS S+D T+ +W S+ + V I L+
Sbjct: 351 DRPVKTFQGHTNEVNAIKWDP-SGMLLASCSDDMTLKIW---------SMKQEVCIHDLQ 400
Query: 128 GHSKRVGIVAWHPTA-------RNVLL-SAGCDNAIIIWNVGTGEALINLDDMHSDMIYN 179
H+K + + W PT N++L SA D+ + +W++ G L H + +Y+
Sbjct: 401 AHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTL-TKHQEPVYS 459
Query: 180 VSWNRNGSLICTASKDKKVRVIDPRKQEIV 209
V+++ +G + + S DK V + + + +V
Sbjct: 460 VAFSPDGKYLASGSFDKCVHIWNTQSGNLV 489
Score = 50.1 bits (118), Expect = 4e-06
Identities = 35/116 (30%), Positives = 55/116 (47%), Gaps = 10/116 (8%)
Query: 90 PHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRVGIVAWHPTARNVLLSA 149
P+++ ++AS S D TV +W I T +LT+ H + V VA+ P + L S
Sbjct: 421 PNSNIMLASASFDSTVRLWDIERGVCTHTLTK-------HQEPVYSVAFSPDGK-YLASG 472
Query: 150 GCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWNRNGSLICTASKDKKVRVIDPRK 205
D + IWN +G + + I+ V WN G + ++ D V V+D RK
Sbjct: 473 SFDKCVHIWNTQSGNLVHSYRGTGG--IFEVCWNARGDKVGASASDGSVCVLDLRK 526
Score = 48.1 bits (113), Expect = 2e-05
Identities = 40/137 (29%), Positives = 58/137 (42%), Gaps = 11/137 (8%)
Query: 78 GHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPEN---GLTLSLTEPVVILEGH----S 130
GH V W P +D ++ASGS D T +W + EN G T + + GH +
Sbjct: 179 GHESEVFICAWNPVSD-LLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSN 237
Query: 131 KRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWNRNGSLIC 190
K V + W+ T +L + D IW L + H I+ + WNR G+ I
Sbjct: 238 KDVTSLDWN-TNGTLLATGSYDGFARIWTEDGN--LASTLGQHKGPIFALKWNRKGNYIL 294
Query: 191 TASKDKKVRVIDPRKQE 207
+A DK + D E
Sbjct: 295 SAGVDKTTIIWDAHTGE 311
Score = 47.4 bits (111), Expect = 3e-05
Identities = 61/267 (22%), Positives = 102/267 (38%), Gaps = 56/267 (20%)
Query: 78 GHTGP----VLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRV 133
GH P V +DW N ++A+GS D +W E+G S L H +
Sbjct: 231 GHDVPSNKDVTSLDWNT-NGTLLATGSYDGFARIWT--EDGNLAST------LGQHKGPI 281
Query: 134 GIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWNRNGSL----- 188
+ W+ N +LSAG D IIW+ TGEA HS +V W N +
Sbjct: 282 FALKWNRKG-NYILSAGVDKTTIIWDAHTGEAKQQF-PFHSAPALDVDWQNNTTFASCST 339
Query: 189 -----ICTASKDKKVRVIDPRKQEIVAEKEKAHEGARPMRAIFLADGNVFTTGFSRMSER 243
+C D+ V+ E+ A K + LA S +
Sbjct: 340 DMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDP-------SGMLLA---------SCSDDM 383
Query: 244 QLALWNPKNMQEPIALHEMDTSNGVLLPF---------YDPDTSIIYLCGKGDSSIRYFE 294
L +W +M++ + +H++ N + +P+++I+ DS++R ++
Sbjct: 384 TLKIW---SMKQEVCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWD 440
Query: 295 ITDESPYVHYLNTFSSKEPQRGMGYMP 321
I + H L +EP + + P
Sbjct: 441 I-ERGVCTHTLT--KHQEPVYSVAFSP 464
Score = 43.5 bits (101), Expect = 4e-04
Identities = 48/222 (21%), Positives = 86/222 (38%), Gaps = 53/222 (23%)
Query: 75 TVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVW---------QIP-----------ENG 114
T+ H GP+ + W + ++++G D T ++W Q P +N
Sbjct: 273 TLGQHKGPIFALKWNRKGNYILSAG-VDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNN 331
Query: 115 LT--------------LSLTEPVVILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNV 160
T L PV +GH+ V + W P+ +L S D + IW++
Sbjct: 332 TTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGM-LLASCSDDMTLKIWSM 390
Query: 161 GTGEALINLDDMHSDMIYNVSWNRNGS---------LICTASKDKKVRVIDPRKQEIVAE 211
E I+ H+ IY + W+ G ++ +AS D VR+ D +
Sbjct: 391 -KQEVCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHT 449
Query: 212 KEKAHEGARPMRAI-FLADGNVFTTGFSRMSERQLALWNPKN 252
K E P+ ++ F DG +G ++ + +WN ++
Sbjct: 450 LTKHQE---PVYSVAFSPDGKYLASG---SFDKCVHIWNTQS 485
Score = 39.3 bits (90), Expect = 0.008
Identities = 26/89 (29%), Positives = 41/89 (46%), Gaps = 14/89 (15%)
Query: 125 ILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNV-----GTGEALI--------NLDD 171
+L GH V I AW+P + ++L S D+ IWN+ G L+ D
Sbjct: 176 VLRGHESEVFICAWNPVS-DLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDV 234
Query: 172 MHSDMIYNVSWNRNGSLICTASKDKKVRV 200
+ + ++ WN NG+L+ T S D R+
Sbjct: 235 PSNKDVTSLDWNTNGTLLATGSYDGFARI 263
>gi|213021186 transducin beta-like 1X isoform a [Homo sapiens]
Length = 577
Score = 59.3 bits (142), Expect = 7e-09
Identities = 41/150 (27%), Positives = 74/150 (49%), Gaps = 21/150 (14%)
Query: 70 DKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVI--LE 127
D+ T GHT V I W P + ++AS S+D T+ +W S+ + V I L+
Sbjct: 402 DRPVKTFQGHTNEVNAIKWDP-SGMLLASCSDDMTLKIW---------SMKQEVCIHDLQ 451
Query: 128 GHSKRVGIVAWHPTA-------RNVLL-SAGCDNAIIIWNVGTGEALINLDDMHSDMIYN 179
H+K + + W PT N++L SA D+ + +W++ G L H + +Y+
Sbjct: 452 AHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTL-TKHQEPVYS 510
Query: 180 VSWNRNGSLICTASKDKKVRVIDPRKQEIV 209
V+++ +G + + S DK V + + + +V
Sbjct: 511 VAFSPDGKYLASGSFDKCVHIWNTQSGNLV 540
Score = 50.1 bits (118), Expect = 4e-06
Identities = 35/116 (30%), Positives = 55/116 (47%), Gaps = 10/116 (8%)
Query: 90 PHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRVGIVAWHPTARNVLLSA 149
P+++ ++AS S D TV +W I T +LT+ H + V VA+ P + L S
Sbjct: 472 PNSNIMLASASFDSTVRLWDIERGVCTHTLTK-------HQEPVYSVAFSPDGK-YLASG 523
Query: 150 GCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWNRNGSLICTASKDKKVRVIDPRK 205
D + IWN +G + + I+ V WN G + ++ D V V+D RK
Sbjct: 524 SFDKCVHIWNTQSGNLVHSYRGTGG--IFEVCWNARGDKVGASASDGSVCVLDLRK 577
Score = 48.1 bits (113), Expect = 2e-05
Identities = 40/137 (29%), Positives = 58/137 (42%), Gaps = 11/137 (8%)
Query: 78 GHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPEN---GLTLSLTEPVVILEGH----S 130
GH V W P +D ++ASGS D T +W + EN G T + + GH +
Sbjct: 230 GHESEVFICAWNPVSD-LLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSN 288
Query: 131 KRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWNRNGSLIC 190
K V + W+ T +L + D IW L + H I+ + WNR G+ I
Sbjct: 289 KDVTSLDWN-TNGTLLATGSYDGFARIWTEDGN--LASTLGQHKGPIFALKWNRKGNYIL 345
Query: 191 TASKDKKVRVIDPRKQE 207
+A DK + D E
Sbjct: 346 SAGVDKTTIIWDAHTGE 362
Score = 47.4 bits (111), Expect = 3e-05
Identities = 61/267 (22%), Positives = 102/267 (38%), Gaps = 56/267 (20%)
Query: 78 GHTGP----VLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRV 133
GH P V +DW N ++A+GS D +W E+G S L H +
Sbjct: 282 GHDVPSNKDVTSLDWNT-NGTLLATGSYDGFARIWT--EDGNLAST------LGQHKGPI 332
Query: 134 GIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWNRNGSL----- 188
+ W+ N +LSAG D IIW+ TGEA HS +V W N +
Sbjct: 333 FALKWNRKG-NYILSAGVDKTTIIWDAHTGEAKQQF-PFHSAPALDVDWQNNTTFASCST 390
Query: 189 -----ICTASKDKKVRVIDPRKQEIVAEKEKAHEGARPMRAIFLADGNVFTTGFSRMSER 243
+C D+ V+ E+ A K + LA S +
Sbjct: 391 DMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDP-------SGMLLA---------SCSDDM 434
Query: 244 QLALWNPKNMQEPIALHEMDTSNGVLLPF---------YDPDTSIIYLCGKGDSSIRYFE 294
L +W +M++ + +H++ N + +P+++I+ DS++R ++
Sbjct: 435 TLKIW---SMKQEVCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWD 491
Query: 295 ITDESPYVHYLNTFSSKEPQRGMGYMP 321
I + H L +EP + + P
Sbjct: 492 I-ERGVCTHTLT--KHQEPVYSVAFSP 515
Score = 43.5 bits (101), Expect = 4e-04
Identities = 48/222 (21%), Positives = 86/222 (38%), Gaps = 53/222 (23%)
Query: 75 TVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVW---------QIP-----------ENG 114
T+ H GP+ + W + ++++G D T ++W Q P +N
Sbjct: 324 TLGQHKGPIFALKWNRKGNYILSAG-VDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNN 382
Query: 115 LT--------------LSLTEPVVILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNV 160
T L PV +GH+ V + W P+ +L S D + IW++
Sbjct: 383 TTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGM-LLASCSDDMTLKIWSM 441
Query: 161 GTGEALINLDDMHSDMIYNVSWNRNGS---------LICTASKDKKVRVIDPRKQEIVAE 211
E I+ H+ IY + W+ G ++ +AS D VR+ D +
Sbjct: 442 -KQEVCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHT 500
Query: 212 KEKAHEGARPMRAI-FLADGNVFTTGFSRMSERQLALWNPKN 252
K E P+ ++ F DG +G ++ + +WN ++
Sbjct: 501 LTKHQE---PVYSVAFSPDGKYLASG---SFDKCVHIWNTQS 536
Score = 39.3 bits (90), Expect = 0.008
Identities = 26/89 (29%), Positives = 41/89 (46%), Gaps = 14/89 (15%)
Query: 125 ILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNV-----GTGEALI--------NLDD 171
+L GH V I AW+P + ++L S D+ IWN+ G L+ D
Sbjct: 227 VLRGHESEVFICAWNPVS-DLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDV 285
Query: 172 MHSDMIYNVSWNRNGSLICTASKDKKVRV 200
+ + ++ WN NG+L+ T S D R+
Sbjct: 286 PSNKDVTSLDWNTNGTLLATGSYDGFARI 314
>gi|5032159 transducin beta-like 1X isoform a [Homo sapiens]
Length = 577
Score = 59.3 bits (142), Expect = 7e-09
Identities = 41/150 (27%), Positives = 74/150 (49%), Gaps = 21/150 (14%)
Query: 70 DKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVI--LE 127
D+ T GHT V I W P + ++AS S+D T+ +W S+ + V I L+
Sbjct: 402 DRPVKTFQGHTNEVNAIKWDP-SGMLLASCSDDMTLKIW---------SMKQEVCIHDLQ 451
Query: 128 GHSKRVGIVAWHPTA-------RNVLL-SAGCDNAIIIWNVGTGEALINLDDMHSDMIYN 179
H+K + + W PT N++L SA D+ + +W++ G L H + +Y+
Sbjct: 452 AHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTL-TKHQEPVYS 510
Query: 180 VSWNRNGSLICTASKDKKVRVIDPRKQEIV 209
V+++ +G + + S DK V + + + +V
Sbjct: 511 VAFSPDGKYLASGSFDKCVHIWNTQSGNLV 540
Score = 50.1 bits (118), Expect = 4e-06
Identities = 35/116 (30%), Positives = 55/116 (47%), Gaps = 10/116 (8%)
Query: 90 PHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRVGIVAWHPTARNVLLSA 149
P+++ ++AS S D TV +W I T +LT+ H + V VA+ P + L S
Sbjct: 472 PNSNIMLASASFDSTVRLWDIERGVCTHTLTK-------HQEPVYSVAFSPDGK-YLASG 523
Query: 150 GCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWNRNGSLICTASKDKKVRVIDPRK 205
D + IWN +G + + I+ V WN G + ++ D V V+D RK
Sbjct: 524 SFDKCVHIWNTQSGNLVHSYRGTGG--IFEVCWNARGDKVGASASDGSVCVLDLRK 577
Score = 48.1 bits (113), Expect = 2e-05
Identities = 40/137 (29%), Positives = 58/137 (42%), Gaps = 11/137 (8%)
Query: 78 GHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPEN---GLTLSLTEPVVILEGH----S 130
GH V W P +D ++ASGS D T +W + EN G T + + GH +
Sbjct: 230 GHESEVFICAWNPVSD-LLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSN 288
Query: 131 KRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWNRNGSLIC 190
K V + W+ T +L + D IW L + H I+ + WNR G+ I
Sbjct: 289 KDVTSLDWN-TNGTLLATGSYDGFARIWTEDGN--LASTLGQHKGPIFALKWNRKGNYIL 345
Query: 191 TASKDKKVRVIDPRKQE 207
+A DK + D E
Sbjct: 346 SAGVDKTTIIWDAHTGE 362
Score = 47.4 bits (111), Expect = 3e-05
Identities = 61/267 (22%), Positives = 102/267 (38%), Gaps = 56/267 (20%)
Query: 78 GHTGP----VLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRV 133
GH P V +DW N ++A+GS D +W E+G S L H +
Sbjct: 282 GHDVPSNKDVTSLDWNT-NGTLLATGSYDGFARIWT--EDGNLAST------LGQHKGPI 332
Query: 134 GIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWNRNGSL----- 188
+ W+ N +LSAG D IIW+ TGEA HS +V W N +
Sbjct: 333 FALKWNRKG-NYILSAGVDKTTIIWDAHTGEAKQQF-PFHSAPALDVDWQNNTTFASCST 390
Query: 189 -----ICTASKDKKVRVIDPRKQEIVAEKEKAHEGARPMRAIFLADGNVFTTGFSRMSER 243
+C D+ V+ E+ A K + LA S +
Sbjct: 391 DMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDP-------SGMLLA---------SCSDDM 434
Query: 244 QLALWNPKNMQEPIALHEMDTSNGVLLPF---------YDPDTSIIYLCGKGDSSIRYFE 294
L +W +M++ + +H++ N + +P+++I+ DS++R ++
Sbjct: 435 TLKIW---SMKQEVCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWD 491
Query: 295 ITDESPYVHYLNTFSSKEPQRGMGYMP 321
I + H L +EP + + P
Sbjct: 492 I-ERGVCTHTLT--KHQEPVYSVAFSP 515
Score = 43.5 bits (101), Expect = 4e-04
Identities = 48/222 (21%), Positives = 86/222 (38%), Gaps = 53/222 (23%)
Query: 75 TVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVW---------QIP-----------ENG 114
T+ H GP+ + W + ++++G D T ++W Q P +N
Sbjct: 324 TLGQHKGPIFALKWNRKGNYILSAG-VDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNN 382
Query: 115 LT--------------LSLTEPVVILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNV 160
T L PV +GH+ V + W P+ +L S D + IW++
Sbjct: 383 TTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGM-LLASCSDDMTLKIWSM 441
Query: 161 GTGEALINLDDMHSDMIYNVSWNRNGS---------LICTASKDKKVRVIDPRKQEIVAE 211
E I+ H+ IY + W+ G ++ +AS D VR+ D +
Sbjct: 442 -KQEVCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHT 500
Query: 212 KEKAHEGARPMRAI-FLADGNVFTTGFSRMSERQLALWNPKN 252
K E P+ ++ F DG +G ++ + +WN ++
Sbjct: 501 LTKHQE---PVYSVAFSPDGKYLASG---SFDKCVHIWNTQS 536
Score = 39.3 bits (90), Expect = 0.008
Identities = 26/89 (29%), Positives = 41/89 (46%), Gaps = 14/89 (15%)
Query: 125 ILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNV-----GTGEALI--------NLDD 171
+L GH V I AW+P + ++L S D+ IWN+ G L+ D
Sbjct: 227 VLRGHESEVFICAWNPVS-DLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDV 285
Query: 172 MHSDMIYNVSWNRNGSLICTASKDKKVRV 200
+ + ++ WN NG+L+ T S D R+
Sbjct: 286 PSNKDVTSLDWNTNGTLLATGSYDGFARI 314
>gi|19913367 transducin beta-like 1Y [Homo sapiens]
Length = 522
Score = 59.3 bits (142), Expect = 7e-09
Identities = 40/148 (27%), Positives = 71/148 (47%), Gaps = 17/148 (11%)
Query: 70 DKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGH 129
D T GHT V I W P + ++AS S+D T+ +W + ++ V L+ H
Sbjct: 349 DHPVKTFQGHTNEVNAIKWDP-SGMLLASCSDDMTLKIWSMKQDAC-------VHDLQAH 400
Query: 130 SKRVGIVAWHPT--------ARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVS 181
SK + + W PT + +L SA D+ + +W+V G L H + +Y+V+
Sbjct: 401 SKEIYTIKWSPTGPATSNPNSSIMLASASFDSTVRLWDVEQGVCTHTL-MKHQEPVYSVA 459
Query: 182 WNRNGSLICTASKDKKVRVIDPRKQEIV 209
++ +G + + S DK V + + + +V
Sbjct: 460 FSPDGKYLASGSFDKYVHIWNTQSGSLV 487
Score = 47.8 bits (112), Expect = 2e-05
Identities = 49/222 (22%), Positives = 90/222 (40%), Gaps = 53/222 (23%)
Query: 75 TVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVW---------QIP-----------ENG 114
T+ H GP+ + W + V+++G D T ++W Q P +N
Sbjct: 271 TLGQHKGPIFALKWNKKGNYVLSAG-VDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNN 329
Query: 115 LT--------------LSLTEPVVILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNV 160
+T L PV +GH+ V + W P+ +L S D + IW++
Sbjct: 330 MTFASCSTDMCIHVCRLGCDHPVKTFQGHTNEVNAIKWDPSGM-LLASCSDDMTLKIWSM 388
Query: 161 GTGEALINLDDMHSDMIYNVSWNRNGS---------LICTASKDKKVRVIDPRKQEIVAE 211
+A ++ HS IY + W+ G ++ +AS D VR+ D +Q +
Sbjct: 389 -KQDACVHDLQAHSKEIYTIKWSPTGPATSNPNSSIMLASASFDSTVRLWDV-EQGVCTH 446
Query: 212 KEKAHEGARPMRAI-FLADGNVFTTGFSRMSERQLALWNPKN 252
H+ P+ ++ F DG +G ++ + +WN ++
Sbjct: 447 TLMKHQ--EPVYSVAFSPDGKYLASG---SFDKYVHIWNTQS 483
Score = 45.4 bits (106), Expect = 1e-04
Identities = 34/132 (25%), Positives = 57/132 (43%), Gaps = 18/132 (13%)
Query: 79 HTGPVLDIDWCP--------HNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHS 130
H+ + I W P ++ ++AS S D TV +W + + T +L + H
Sbjct: 400 HSKEIYTIKWSPTGPATSNPNSSIMLASASFDSTVRLWDVEQGVCTHTLMK-------HQ 452
Query: 131 KRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWNRNGSLIC 190
+ V VA+ P + L S D + IWN +G + + I+ V WN G +
Sbjct: 453 EPVYSVAFSPDGK-YLASGSFDKYVHIWNTQSGSLVHSYQGTGG--IFEVCWNARGDKVG 509
Query: 191 TASKDKKVRVID 202
++ D V V+D
Sbjct: 510 ASASDGSVCVLD 521
Score = 45.1 bits (105), Expect = 1e-04
Identities = 37/137 (27%), Positives = 56/137 (40%), Gaps = 11/137 (8%)
Query: 78 GHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPEN---GLTLSLTEPVVILEGH----S 130
GH V W P +D ++ASGS D T +W + EN G T + + GH +
Sbjct: 177 GHESEVFICAWNPVSD-LLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSN 235
Query: 131 KRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWNRNGSLIC 190
K V + W+ +L D IW L + H I+ + WN+ G+ +
Sbjct: 236 KDVTSLDWNSDG-TLLAMGSYDGFARIWTENGN--LASTLGQHKGPIFALKWNKKGNYVL 292
Query: 191 TASKDKKVRVIDPRKQE 207
+A DK + D E
Sbjct: 293 SAGVDKTTIIWDAHTGE 309
Score = 43.1 bits (100), Expect = 5e-04
Identities = 60/267 (22%), Positives = 100/267 (37%), Gaps = 56/267 (20%)
Query: 78 GHTGP----VLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRV 133
GH P V +DW + ++A GS D +W ENG S L H +
Sbjct: 229 GHDVPSNKDVTSLDW-NSDGTLLAMGSYDGFARIWT--ENGNLAST------LGQHKGPI 279
Query: 134 GIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWNRNGSL----- 188
+ W+ N +LSAG D IIW+ TGEA HS +V W N +
Sbjct: 280 FALKWNKKG-NYVLSAGVDKTTIIWDAHTGEAKQQF-PFHSAPALDVDWQNNMTFASCST 337
Query: 189 -----ICTASKDKKVRVIDPRKQEIVAEKEKAHEGARPMRAIFLADGNVFTTGFSRMSER 243
+C D V+ E+ A K + LA S +
Sbjct: 338 DMCIHVCRLGCDHPVKTFQGHTNEVNAIKWDP-------SGMLLA---------SCSDDM 381
Query: 244 QLALWNPKNMQEPIALHEMDTSNGVLLPF---------YDPDTSIIYLCGKGDSSIRYFE 294
L +W +M++ +H++ + + +P++SI+ DS++R ++
Sbjct: 382 TLKIW---SMKQDACVHDLQAHSKEIYTIKWSPTGPATSNPNSSIMLASASFDSTVRLWD 438
Query: 295 ITDESPYVHYLNTFSSKEPQRGMGYMP 321
+ ++ H L +EP + + P
Sbjct: 439 V-EQGVCTHTL--MKHQEPVYSVAFSP 462
Score = 35.4 bits (80), Expect = 0.11
Identities = 28/105 (26%), Positives = 45/105 (42%), Gaps = 22/105 (20%)
Query: 109 QIPENGLTLSLTEPVVILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNV-----GTG 163
+IP N T +L GH V I AW+P + ++L S D+ IWN+ G
Sbjct: 166 EIPPNKAT--------VLRGHESEVFICAWNPVS-DLLASGSGDSTARIWNLNENSNGGS 216
Query: 164 EALI--------NLDDMHSDMIYNVSWNRNGSLICTASKDKKVRV 200
L+ D + + ++ WN +G+L+ S D R+
Sbjct: 217 TQLVLRHCIREGGHDVPSNKDVTSLDWNSDGTLLAMGSYDGFARI 261
>gi|19913365 transducin beta-like 1Y [Homo sapiens]
Length = 522
Score = 59.3 bits (142), Expect = 7e-09
Identities = 40/148 (27%), Positives = 71/148 (47%), Gaps = 17/148 (11%)
Query: 70 DKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGH 129
D T GHT V I W P + ++AS S+D T+ +W + ++ V L+ H
Sbjct: 349 DHPVKTFQGHTNEVNAIKWDP-SGMLLASCSDDMTLKIWSMKQDAC-------VHDLQAH 400
Query: 130 SKRVGIVAWHPT--------ARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVS 181
SK + + W PT + +L SA D+ + +W+V G L H + +Y+V+
Sbjct: 401 SKEIYTIKWSPTGPATSNPNSSIMLASASFDSTVRLWDVEQGVCTHTL-MKHQEPVYSVA 459
Query: 182 WNRNGSLICTASKDKKVRVIDPRKQEIV 209
++ +G + + S DK V + + + +V
Sbjct: 460 FSPDGKYLASGSFDKYVHIWNTQSGSLV 487
Score = 47.8 bits (112), Expect = 2e-05
Identities = 49/222 (22%), Positives = 90/222 (40%), Gaps = 53/222 (23%)
Query: 75 TVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVW---------QIP-----------ENG 114
T+ H GP+ + W + V+++G D T ++W Q P +N
Sbjct: 271 TLGQHKGPIFALKWNKKGNYVLSAG-VDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNN 329
Query: 115 LT--------------LSLTEPVVILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNV 160
+T L PV +GH+ V + W P+ +L S D + IW++
Sbjct: 330 MTFASCSTDMCIHVCRLGCDHPVKTFQGHTNEVNAIKWDPSGM-LLASCSDDMTLKIWSM 388
Query: 161 GTGEALINLDDMHSDMIYNVSWNRNGS---------LICTASKDKKVRVIDPRKQEIVAE 211
+A ++ HS IY + W+ G ++ +AS D VR+ D +Q +
Sbjct: 389 -KQDACVHDLQAHSKEIYTIKWSPTGPATSNPNSSIMLASASFDSTVRLWDV-EQGVCTH 446
Query: 212 KEKAHEGARPMRAI-FLADGNVFTTGFSRMSERQLALWNPKN 252
H+ P+ ++ F DG +G ++ + +WN ++
Sbjct: 447 TLMKHQ--EPVYSVAFSPDGKYLASG---SFDKYVHIWNTQS 483
Score = 45.4 bits (106), Expect = 1e-04
Identities = 34/132 (25%), Positives = 57/132 (43%), Gaps = 18/132 (13%)
Query: 79 HTGPVLDIDWCP--------HNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHS 130
H+ + I W P ++ ++AS S D TV +W + + T +L + H
Sbjct: 400 HSKEIYTIKWSPTGPATSNPNSSIMLASASFDSTVRLWDVEQGVCTHTLMK-------HQ 452
Query: 131 KRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWNRNGSLIC 190
+ V VA+ P + L S D + IWN +G + + I+ V WN G +
Sbjct: 453 EPVYSVAFSPDGK-YLASGSFDKYVHIWNTQSGSLVHSYQGTGG--IFEVCWNARGDKVG 509
Query: 191 TASKDKKVRVID 202
++ D V V+D
Sbjct: 510 ASASDGSVCVLD 521
Score = 45.1 bits (105), Expect = 1e-04
Identities = 37/137 (27%), Positives = 56/137 (40%), Gaps = 11/137 (8%)
Query: 78 GHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPEN---GLTLSLTEPVVILEGH----S 130
GH V W P +D ++ASGS D T +W + EN G T + + GH +
Sbjct: 177 GHESEVFICAWNPVSD-LLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSN 235
Query: 131 KRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWNRNGSLIC 190
K V + W+ +L D IW L + H I+ + WN+ G+ +
Sbjct: 236 KDVTSLDWNSDG-TLLAMGSYDGFARIWTENGN--LASTLGQHKGPIFALKWNKKGNYVL 292
Query: 191 TASKDKKVRVIDPRKQE 207
+A DK + D E
Sbjct: 293 SAGVDKTTIIWDAHTGE 309
Score = 43.1 bits (100), Expect = 5e-04
Identities = 60/267 (22%), Positives = 100/267 (37%), Gaps = 56/267 (20%)
Query: 78 GHTGP----VLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRV 133
GH P V +DW + ++A GS D +W ENG S L H +
Sbjct: 229 GHDVPSNKDVTSLDW-NSDGTLLAMGSYDGFARIWT--ENGNLAST------LGQHKGPI 279
Query: 134 GIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWNRNGSL----- 188
+ W+ N +LSAG D IIW+ TGEA HS +V W N +
Sbjct: 280 FALKWNKKG-NYVLSAGVDKTTIIWDAHTGEAKQQF-PFHSAPALDVDWQNNMTFASCST 337
Query: 189 -----ICTASKDKKVRVIDPRKQEIVAEKEKAHEGARPMRAIFLADGNVFTTGFSRMSER 243
+C D V+ E+ A K + LA S +
Sbjct: 338 DMCIHVCRLGCDHPVKTFQGHTNEVNAIKWDP-------SGMLLA---------SCSDDM 381
Query: 244 QLALWNPKNMQEPIALHEMDTSNGVLLPF---------YDPDTSIIYLCGKGDSSIRYFE 294
L +W +M++ +H++ + + +P++SI+ DS++R ++
Sbjct: 382 TLKIW---SMKQDACVHDLQAHSKEIYTIKWSPTGPATSNPNSSIMLASASFDSTVRLWD 438
Query: 295 ITDESPYVHYLNTFSSKEPQRGMGYMP 321
+ ++ H L +EP + + P
Sbjct: 439 V-EQGVCTHTL--MKHQEPVYSVAFSP 462
Score = 35.4 bits (80), Expect = 0.11
Identities = 28/105 (26%), Positives = 45/105 (42%), Gaps = 22/105 (20%)
Query: 109 QIPENGLTLSLTEPVVILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNV-----GTG 163
+IP N T +L GH V I AW+P + ++L S D+ IWN+ G
Sbjct: 166 EIPPNKAT--------VLRGHESEVFICAWNPVS-DLLASGSGDSTARIWNLNENSNGGS 216
Query: 164 EALI--------NLDDMHSDMIYNVSWNRNGSLICTASKDKKVRV 200
L+ D + + ++ WN +G+L+ S D R+
Sbjct: 217 TQLVLRHCIREGGHDVPSNKDVTSLDWNSDGTLLAMGSYDGFARI 261
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.412
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,425,458
Number of Sequences: 37866
Number of extensions: 832419
Number of successful extensions: 3162
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 97
Number of HSP's successfully gapped in prelim test: 171
Number of HSP's that attempted gapping in prelim test: 2241
Number of HSP's gapped (non-prelim): 752
length of query: 474
length of database: 18,247,518
effective HSP length: 106
effective length of query: 368
effective length of database: 14,233,722
effective search space: 5238009696
effective search space used: 5238009696
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.