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Search of human proteins with 72534732
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|72534732 dehydrogenase/reductase (SDR family) member 12
isoform 1 [Homo sapiens]
(271 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|72534732 dehydrogenase/reductase (SDR family) member 12 isofo... 563 e-161
gi|13375997 dehydrogenase/reductase (SDR family) member 12 isofo... 382 e-106
gi|166795268 retinol dehydrogenase 11 [Homo sapiens] 78 7e-15
gi|193804850 dehydrogenase/reductase (SDR family) X-linked [Homo... 78 9e-15
gi|186928839 retinol dehydrogenase 12 [Homo sapiens] 77 2e-14
gi|225579078 retinol dehydrogenase 13 isoform 1 [Homo sapiens] 70 2e-12
gi|19923931 retinol dehydrogenase 13 isoform 2 [Homo sapiens] 70 2e-12
gi|10190746 retinol dehydrogenase 14 (all-trans and 9-cis) [Homo... 64 2e-10
gi|7706523 WW domain-containing oxidoreductase isoform 1 [Homo s... 47 1e-05
gi|142976729 estradiol 17-beta-dehydrogenase 11 [Homo sapiens] 45 7e-05
gi|50726952 retinol dehydrogenase 5 (11-cis and 9-cis) [Homo sap... 45 9e-05
gi|210032110 hydroxysteroid (17-beta) dehydrogenase 13 isoform A... 45 9e-05
gi|11321561 hemopexin precursor [Homo sapiens] 41 0.001
gi|146231950 dehydrogenase/reductase (SDR family) member 13 [Hom... 40 0.003
gi|40548397 NADP-dependent retinol dehydrogenase/reductase [Homo... 37 0.014
gi|214010158 NADP-dependent retinol dehydrogenase/reductase [Hom... 37 0.014
gi|214010156 NADP-dependent retinol dehydrogenase/reductase [Hom... 37 0.014
gi|22758144 NADP-dependent retinol dehydrogenase/reductase [Homo... 37 0.014
gi|40254986 hydroxysteroid dehydrogenase like 2 [Homo sapiens] 37 0.024
gi|223646115 short chain dehydrogenase/reductase family 16C, mem... 36 0.041
gi|210032112 hydroxysteroid (17-beta) dehydrogenase 13 isoform B... 35 0.091
gi|40807363 epidermal retinal dehydrogenase 2 [Homo sapiens] 34 0.15
gi|7705421 hydroxysteroid (17-beta) dehydrogenase 7 [Homo sapiens] 33 0.34
gi|38679977 acetyl-Coenzyme A carboxylase alpha isoform 2 [Homo ... 33 0.34
gi|38679974 acetyl-Coenzyme A carboxylase alpha isoform 4 [Homo ... 33 0.34
gi|38679971 acetyl-Coenzyme A carboxylase alpha isoform 3 [Homo ... 33 0.34
gi|38679967 acetyl-Coenzyme A carboxylase alpha isoform 2 [Homo ... 33 0.34
gi|38679960 acetyl-Coenzyme A carboxylase alpha isoform 1 [Homo ... 33 0.34
gi|154800453 tastin isoform 1 [Homo sapiens] 32 0.59
gi|22507405 short chain dehydrogenase/reductase family 9C, membe... 30 1.7
>gi|72534732 dehydrogenase/reductase (SDR family) member 12 isoform
1 [Homo sapiens]
Length = 271
Score = 563 bits (1450), Expect = e-161
Identities = 271/271 (100%), Positives = 271/271 (100%)
Query: 1 MNLHVKTLSLMTWRSRFLEESFWSLEETAALAKQLPLKSPSENIFLHIVDLSDPKQIWKF 60
MNLHVKTLSLMTWRSRFLEESFWSLEETAALAKQLPLKSPSENIFLHIVDLSDPKQIWKF
Sbjct: 1 MNLHVKTLSLMTWRSRFLEESFWSLEETAALAKQLPLKSPSENIFLHIVDLSDPKQIWKF 60
Query: 61 VENFKQEHKLHVLINNAGCMVNKRELTEDGLEKNFAANTLGVYILTTGLIPVLEKEHDPR 120
VENFKQEHKLHVLINNAGCMVNKRELTEDGLEKNFAANTLGVYILTTGLIPVLEKEHDPR
Sbjct: 61 VENFKQEHKLHVLINNAGCMVNKRELTEDGLEKNFAANTLGVYILTTGLIPVLEKEHDPR 120
Query: 121 VITVSSGGMLVQKLNTNDLQSERTPFDGTMVYAQNKRQQVVLTERWAQGHPAIHFSSMHP 180
VITVSSGGMLVQKLNTNDLQSERTPFDGTMVYAQNKRQQVVLTERWAQGHPAIHFSSMHP
Sbjct: 121 VITVSSGGMLVQKLNTNDLQSERTPFDGTMVYAQNKRQQVVLTERWAQGHPAIHFSSMHP 180
Query: 181 GWADTPDRNEQELRKVVGEAQTASPLPRFLEIMMHEGKCQPQGHSSNDLEACWSSGGGEQ 240
GWADTPDRNEQELRKVVGEAQTASPLPRFLEIMMHEGKCQPQGHSSNDLEACWSSGGGEQ
Sbjct: 181 GWADTPDRNEQELRKVVGEAQTASPLPRFLEIMMHEGKCQPQGHSSNDLEACWSSGGGEQ 240
Query: 241 NSLPDWPHQLHDLRQLTWALCSSFLLYKQGN 271
NSLPDWPHQLHDLRQLTWALCSSFLLYKQGN
Sbjct: 241 NSLPDWPHQLHDLRQLTWALCSSFLLYKQGN 271
>gi|13375997 dehydrogenase/reductase (SDR family) member 12 isoform
2 [Homo sapiens]
Length = 242
Score = 382 bits (980), Expect = e-106
Identities = 186/186 (100%), Positives = 186/186 (100%)
Query: 1 MNLHVKTLSLMTWRSRFLEESFWSLEETAALAKQLPLKSPSENIFLHIVDLSDPKQIWKF 60
MNLHVKTLSLMTWRSRFLEESFWSLEETAALAKQLPLKSPSENIFLHIVDLSDPKQIWKF
Sbjct: 1 MNLHVKTLSLMTWRSRFLEESFWSLEETAALAKQLPLKSPSENIFLHIVDLSDPKQIWKF 60
Query: 61 VENFKQEHKLHVLINNAGCMVNKRELTEDGLEKNFAANTLGVYILTTGLIPVLEKEHDPR 120
VENFKQEHKLHVLINNAGCMVNKRELTEDGLEKNFAANTLGVYILTTGLIPVLEKEHDPR
Sbjct: 61 VENFKQEHKLHVLINNAGCMVNKRELTEDGLEKNFAANTLGVYILTTGLIPVLEKEHDPR 120
Query: 121 VITVSSGGMLVQKLNTNDLQSERTPFDGTMVYAQNKRQQVVLTERWAQGHPAIHFSSMHP 180
VITVSSGGMLVQKLNTNDLQSERTPFDGTMVYAQNKRQQVVLTERWAQGHPAIHFSSMHP
Sbjct: 121 VITVSSGGMLVQKLNTNDLQSERTPFDGTMVYAQNKRQQVVLTERWAQGHPAIHFSSMHP 180
Query: 181 GWADTP 186
GWADTP
Sbjct: 181 GWADTP 186
>gi|166795268 retinol dehydrogenase 11 [Homo sapiens]
Length = 318
Score = 78.2 bits (191), Expect = 7e-15
Identities = 49/160 (30%), Positives = 87/160 (54%), Gaps = 4/160 (2%)
Query: 25 LEETAALAKQLPLKSPSENIFLHIVDLSDPKQIWKFVENFKQEHK-LHVLINNAGCMVNK 83
+E+ +AK++ + ++ + + +DLSD K I F + F E K LHVLINNAG M+
Sbjct: 75 VEKGELVAKEIQTTTGNQQVLVRKLDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCP 134
Query: 84 RELTEDGLEKNFAANTLGVYILTTGLIPVLEKEHDPRVITVSSGGMLVQKLNTNDLQSER 143
T DG E + N LG ++LT L+ L++ R++ VSS + +++ ++LQ E+
Sbjct: 135 YSKTADGFEMHIGVNHLGHFLLTHLLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEK 194
Query: 144 TPFDGTMVYAQNKRQQVVLTERWAQ--GHPAIHFSSMHPG 181
++ + Y +K ++ T+ A+ + S+HPG
Sbjct: 195 F-YNAGLAYCHSKLANILFTQELARRLKGSGVTTYSVHPG 233
>gi|193804850 dehydrogenase/reductase (SDR family) X-linked [Homo
sapiens]
Length = 330
Score = 77.8 bits (190), Expect = 9e-15
Identities = 56/142 (39%), Positives = 78/142 (54%), Gaps = 12/142 (8%)
Query: 32 AKQLPLKSPSENI-----FLHIVDLSDPKQIWKFVENFKQEH-KLHVLINNAGCMVNKRE 85
AKQ+ K E + FL+ DL+ I +FV+ FK + LHVLINNAG M+ +
Sbjct: 80 AKQVVSKIKEETLNDKVEFLYC-DLASMTSIRQFVQKFKMKKIPLHVLINNAGVMMVPQR 138
Query: 86 LTEDGLEKNFAANTLGVYILTTGLIPVLEKE----HDPRVITVSSGGMLVQKLNTNDLQS 141
T DG E++F N LG ++LT L+ L++ H RV+TVSS V +LN +DLQS
Sbjct: 139 KTRDGFEEHFGLNYLGHFLLTNLLLDTLKESGSPGHSARVVTVSSATHYVAELNMDDLQS 198
Query: 142 ERTPFDGTMVYAQNKRQQVVLT 163
+ YAQ+K V+ T
Sbjct: 199 SAC-YSPHAAYAQSKLALVLFT 219
>gi|186928839 retinol dehydrogenase 12 [Homo sapiens]
Length = 316
Score = 76.6 bits (187), Expect = 2e-14
Identities = 53/154 (34%), Positives = 79/154 (51%), Gaps = 6/154 (3%)
Query: 32 AKQLPLKSPSENIFLHIVDLSDPKQIWKFVENFKQEHK-LHVLINNAGCMVNKRELTEDG 90
A ++ + + + + + +DLSD K I F E F E K LH+LINNAG M+ T DG
Sbjct: 80 ASEIRVDTKNSQVLVRKLDLSDTKSIRAFAEGFLAEEKQLHILINNAGVMMCPYSKTADG 139
Query: 91 LEKNFAANTLGVYILTTGLIPVLEKEHDPRVITVSSGGMLVQKLNTNDLQSERTPFDGTM 150
E + N LG ++LT L+ L+ RV+ VSS + K+ +DLQSE+ +
Sbjct: 140 FETHLGVNHLGHFLLTYLLLERLKVSAPARVVNVSSVAHHIGKIPFHDLQSEKR-YSRGF 198
Query: 151 VYAQNKRQQVVLTERWA---QGHPAIHFSSMHPG 181
Y +K V+ T A QG + ++HPG
Sbjct: 199 AYCHSKLANVLFTRELAKRLQG-TGVTTYAVHPG 231
>gi|225579078 retinol dehydrogenase 13 isoform 1 [Homo sapiens]
Length = 331
Score = 70.1 bits (170), Expect = 2e-12
Identities = 49/165 (29%), Positives = 85/165 (51%), Gaps = 5/165 (3%)
Query: 25 LEETAALAKQLPLKSPSENIFLHIVDLSDPKQIWKFVENF-KQEHKLHVLINNAGCMVNK 83
+E+ A AK + ++ + ++ +DL+ K I +F ++E ++ +LINNAG M
Sbjct: 72 MEKCEAAAKDIRGETLNHHVNARHLDLASLKSIREFAAKIIEEEERVDILINNAGVMRCP 131
Query: 84 RELTEDGLEKNFAANTLGVYILTTGLIPVLEKEHDPRVITVSSGGMLVQKLNTNDLQSER 143
TEDG E F N LG ++LT L+ L+ R+I +SS + ++ +DL +
Sbjct: 132 HWTTEDGFEMQFGVNHLGHFLLTNLLLDKLKASAPSRIINLSSLAHVAGHIDFDDLNWQT 191
Query: 144 TPFDGTMVYAQNKRQQVVLTE---RWAQGHPAIHFSSMHPGWADT 185
++ Y Q+K V+ T+ R QG + +++HPG A T
Sbjct: 192 RKYNTKAAYCQSKLAIVLFTKELSRRLQG-SGVTVNALHPGVART 235
>gi|19923931 retinol dehydrogenase 13 isoform 2 [Homo sapiens]
Length = 260
Score = 70.1 bits (170), Expect = 2e-12
Identities = 49/165 (29%), Positives = 85/165 (51%), Gaps = 5/165 (3%)
Query: 25 LEETAALAKQLPLKSPSENIFLHIVDLSDPKQIWKFVENF-KQEHKLHVLINNAGCMVNK 83
+E+ A AK + ++ + ++ +DL+ K I +F ++E ++ +LINNAG M
Sbjct: 1 MEKCEAAAKDIRGETLNHHVNARHLDLASLKSIREFAAKIIEEEERVDILINNAGVMRCP 60
Query: 84 RELTEDGLEKNFAANTLGVYILTTGLIPVLEKEHDPRVITVSSGGMLVQKLNTNDLQSER 143
TEDG E F N LG ++LT L+ L+ R+I +SS + ++ +DL +
Sbjct: 61 HWTTEDGFEMQFGVNHLGHFLLTNLLLDKLKASAPSRIINLSSLAHVAGHIDFDDLNWQT 120
Query: 144 TPFDGTMVYAQNKRQQVVLTE---RWAQGHPAIHFSSMHPGWADT 185
++ Y Q+K V+ T+ R QG + +++HPG A T
Sbjct: 121 RKYNTKAAYCQSKLAIVLFTKELSRRLQG-SGVTVNALHPGVART 164
>gi|10190746 retinol dehydrogenase 14 (all-trans and 9-cis) [Homo
sapiens]
Length = 336
Score = 63.5 bits (153), Expect = 2e-10
Identities = 42/136 (30%), Positives = 71/136 (52%), Gaps = 4/136 (2%)
Query: 49 VDLSDPKQIWKFVENFKQEH-KLHVLINNAGCMVNKRELTEDGLEKNFAANTLGVYILTT 107
+DL+ + + F + QE +L VLINNAG TEDG E F N LG ++LT
Sbjct: 114 LDLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTEDGFEMQFGVNHLGHFLLTN 173
Query: 108 GLIPVLEKEHDPRVITVSSGGMLVQKLNTNDLQSERTPFDGTMVYAQNKRQQVVLTERWA 167
L+ +L+ R++ VSS +N +DL SE++ ++ + Y+++K ++ T A
Sbjct: 174 LLLGLLKSSAPSRIVVVSSKLYKYGDINFDDLNSEQS-YNKSFCYSRSKLANILFTRELA 232
Query: 168 QGHPA--IHFSSMHPG 181
+ + + +HPG
Sbjct: 233 RRLEGTNVTVNVLHPG 248
>gi|7706523 WW domain-containing oxidoreductase isoform 1 [Homo
sapiens]
Length = 414
Score = 47.4 bits (111), Expect = 1e-05
Identities = 32/79 (40%), Positives = 42/79 (53%), Gaps = 1/79 (1%)
Query: 49 VDLSDPKQIWKFVENFKQEH-KLHVLINNAGCMVNKRELTEDGLEKNFAANTLGVYILTT 107
+DL+ + + F E FK ++ LHVL+ NA LT+DGLE F N LG + L
Sbjct: 182 LDLALLRSVQHFAEAFKAKNVPLHVLVCNAATFALPWSLTKDGLETTFQVNHLGHFYLVQ 241
Query: 108 GLIPVLEKEHDPRVITVSS 126
L VL + RVI VSS
Sbjct: 242 LLQDVLCRSAPARVIVVSS 260
>gi|142976729 estradiol 17-beta-dehydrogenase 11 [Homo sapiens]
Length = 300
Score = 45.1 bits (105), Expect = 7e-05
Identities = 33/105 (31%), Positives = 52/105 (49%), Gaps = 8/105 (7%)
Query: 25 LEETAALAKQLPLKSPSENIFLHIVDLSDPKQIWKFVENFKQE-HKLHVLINNAGCMVNK 83
LEETAA K L K + +VD S+ + I+ + K E + +L+NNAG +
Sbjct: 73 LEETAAKCKGLGAK-----VHTFVVDCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTS 127
Query: 84 REL-TEDG-LEKNFAANTLGVYILTTGLIPVLEKEHDPRVITVSS 126
T+D +EK F N L + T +P + K + ++TV+S
Sbjct: 128 DLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVAS 172
>gi|50726952 retinol dehydrogenase 5 (11-cis and 9-cis) [Homo
sapiens]
Length = 318
Score = 44.7 bits (104), Expect = 9e-05
Identities = 45/172 (26%), Positives = 74/172 (43%), Gaps = 37/172 (21%)
Query: 41 SENIFLHIVDLSDPKQIW---KFVENFKQEHKLHVLINN---AGCMVNKRELTEDGLEKN 94
S + ++D++DP+ + K+VE +E L L+NN AG + LT D ++
Sbjct: 73 SSRLHTTLLDITDPQSVQQAAKWVEMHVKEAGLFGLVNNAGVAGIIGPTPWLTRDDFQRV 132
Query: 95 FAANTLGVYILTTGLIPVLEKEHDPRVITVSS---------GGMLVQKLNTNDLQSERTP 145
NT+G +T L+P+L++ RVI ++S GG V K
Sbjct: 133 LNVNTMGPIGVTLALLPLLQQARG-RVINITSVLGRLAANGGGYCVSKF----------- 180
Query: 146 FDGTMVYAQNKRQQVVLTERWAQGHPAIHFSSMHPGWADTPDRNEQELRKVV 197
G ++ + R+ V H I S + PG+ TP N + L K +
Sbjct: 181 --GLEAFSDSLRRDV--------AHFGIRVSIVEPGFFRTPVTNLESLEKTL 222
>gi|210032110 hydroxysteroid (17-beta) dehydrogenase 13 isoform A
[Homo sapiens]
Length = 300
Score = 44.7 bits (104), Expect = 9e-05
Identities = 28/105 (26%), Positives = 61/105 (58%), Gaps = 8/105 (7%)
Query: 25 LEETAALAKQLPLKSPSENIFLHIVDLSDPKQIWKFVENFKQE-HKLHVLINNAGCMVNK 83
+EETAA ++L + + + ++VD S+ ++I++ + K+E + +++NNAG +
Sbjct: 73 VEETAAECRKLGVTAHA-----YVVDCSNREEIYRSLNQVKKEVGDVTIVVNNAGTVYPA 127
Query: 84 RELT--EDGLEKNFAANTLGVYILTTGLIPVLEKEHDPRVITVSS 126
L+ ++ + K F N LG + +T L+P + + + ++TV+S
Sbjct: 128 DLLSTKDEEITKTFEVNILGHFWITKALLPSMMERNHGHIVTVAS 172
>gi|11321561 hemopexin precursor [Homo sapiens]
Length = 462
Score = 41.2 bits (95), Expect = 0.001
Identities = 34/147 (23%), Positives = 53/147 (36%), Gaps = 15/147 (10%)
Query: 114 EKEHDPRVITVSSGGMLVQKLNTNDLQSERTPFDGTMVYAQNKRQQVVLTERWA------ 167
E + DP V S G +D F G V+ +K + +++ERW
Sbjct: 39 ETKPDPDVTERCSDGWSFDATTLDD-NGTMLFFKGEFVWKSHKWDRELISERWKNFPSPV 97
Query: 168 -----QGHPAIHFSSMHPGWADTPDRNEQELRKVVGEAQTASPLPRFLEIMMHEGKCQPQ 222
QGH ++ W P++ E+ K++ + P P + H G+CQ +
Sbjct: 98 DAAFRQGHNSVFLIKGDKVWVYPPEKKEKGYPKLLQDEFPGIPSPLDAAVECHRGECQAE 157
Query: 223 G--HSSNDLEACWSSGGGEQNSLPDWP 247
G D E W G WP
Sbjct: 158 GVLFFQGDREWFWDLATGTMKE-RSWP 183
>gi|146231950 dehydrogenase/reductase (SDR family) member 13 [Homo
sapiens]
Length = 377
Score = 39.7 bits (91), Expect = 0.003
Identities = 46/179 (25%), Positives = 73/179 (40%), Gaps = 10/179 (5%)
Query: 24 SLEETAALAKQLPLKSPSENIFLHIVDLSDPKQIWKFVENF-KQEHKLHVLINNAGCMVN 82
S E A A L +S + + +DL+ + F F E +L +LI+NAG ++
Sbjct: 69 SQERGEAAAFDLRQESGNNEVIFMALDLASLASVRAFATAFLSSEPRLDILIHNAG--IS 126
Query: 83 KRELTEDGLEKNFAANTLGVYILTTGLIPVLEKEHDPRVITVSSGGMLVQKLNTNDLQSE 142
T + N +G ++LT L+P L+ RV+ V+S +L+ L
Sbjct: 127 SCGRTREAFNLLLRVNHIGPFLLTHLLLPCLKACAPSRVVVVASAAHCRGRLDFKRLDRP 186
Query: 143 RTPFDGTM-VYAQNKRQQVVLTERWAQGHPA--IHFSSMHPGWADTPDRNEQELRKVVG 198
+ + YA K V+ A A + + HPG P +E LR V G
Sbjct: 187 VVGWRQELRAYADTKLANVLFARELANQLEATGVTCYAAHPG----PVNSELFLRHVPG 241
>gi|40548397 NADP-dependent retinol dehydrogenase/reductase [Homo
sapiens]
Length = 319
Score = 37.4 bits (85), Expect = 0.014
Identities = 30/107 (28%), Positives = 50/107 (46%), Gaps = 4/107 (3%)
Query: 25 LEETAALAKQLPLKSPSENIFLHIVDLSDPKQIWKFVENFKQEHKLHVLINNA---GCMV 81
L E+ + A + + L + D + K+ ++V+N E L LINNA G +
Sbjct: 61 LTESGSTALKAETSERLRTVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLA 120
Query: 82 NKRELTEDGLEKNFAANTLGVYILTTGLIPVLEKEHDPRVITVSSGG 128
LT + + N G+ +T ++P+++K RVI VSS G
Sbjct: 121 PTDWLTLEDYREPIEVNLFGLISVTLNMLPLVKKAQG-RVINVSSVG 166
>gi|214010158 NADP-dependent retinol dehydrogenase/reductase [Homo
sapiens]
Length = 319
Score = 37.4 bits (85), Expect = 0.014
Identities = 30/107 (28%), Positives = 50/107 (46%), Gaps = 4/107 (3%)
Query: 25 LEETAALAKQLPLKSPSENIFLHIVDLSDPKQIWKFVENFKQEHKLHVLINNA---GCMV 81
L E+ + A + + L + D + K+ ++V+N E L LINNA G +
Sbjct: 61 LTESGSTALKAETSERLRTVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLA 120
Query: 82 NKRELTEDGLEKNFAANTLGVYILTTGLIPVLEKEHDPRVITVSSGG 128
LT + + N G+ +T ++P+++K RVI VSS G
Sbjct: 121 PTDWLTLEDYREPIEVNLFGLISVTLNMLPLVKKAQG-RVINVSSVG 166
>gi|214010156 NADP-dependent retinol dehydrogenase/reductase [Homo
sapiens]
Length = 319
Score = 37.4 bits (85), Expect = 0.014
Identities = 30/107 (28%), Positives = 50/107 (46%), Gaps = 4/107 (3%)
Query: 25 LEETAALAKQLPLKSPSENIFLHIVDLSDPKQIWKFVENFKQEHKLHVLINNA---GCMV 81
L E+ + A + + L + D + K+ ++V+N E L LINNA G +
Sbjct: 61 LTESGSTALKAETSERLRTVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLA 120
Query: 82 NKRELTEDGLEKNFAANTLGVYILTTGLIPVLEKEHDPRVITVSSGG 128
LT + + N G+ +T ++P+++K RVI VSS G
Sbjct: 121 PTDWLTLEDYREPIEVNLFGLISVTLNMLPLVKKAQG-RVINVSSVG 166
>gi|22758144 NADP-dependent retinol dehydrogenase/reductase [Homo
sapiens]
Length = 319
Score = 37.4 bits (85), Expect = 0.014
Identities = 30/107 (28%), Positives = 50/107 (46%), Gaps = 4/107 (3%)
Query: 25 LEETAALAKQLPLKSPSENIFLHIVDLSDPKQIWKFVENFKQEHKLHVLINNA---GCMV 81
L E+ + A + + L + D + K+ ++V+N E L LINNA G +
Sbjct: 61 LTESGSTALKAETSERLRTVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLA 120
Query: 82 NKRELTEDGLEKNFAANTLGVYILTTGLIPVLEKEHDPRVITVSSGG 128
LT + + N G+ +T ++P+++K RVI VSS G
Sbjct: 121 PTDWLTLEDYREPIEVNLFGLISVTLNMLPLVKKAQG-RVINVSSVG 166
>gi|40254986 hydroxysteroid dehydrogenase like 2 [Homo sapiens]
Length = 418
Score = 36.6 bits (83), Expect = 0.024
Identities = 24/81 (29%), Positives = 39/81 (48%), Gaps = 3/81 (3%)
Query: 48 IVDLSDPKQIWKFVEN-FKQEHKLHVLINNAGC--MVNKRELTEDGLEKNFAANTLGVYI 104
IVD+ D +QI VE K+ + +L+NNA + N + L+ NT G Y+
Sbjct: 72 IVDVRDEQQISAAVEKAIKKFGGIDILVNNASAISLTNTLDTPTKRLDLMMNVNTRGTYL 131
Query: 105 LTTGLIPVLEKEHDPRVITVS 125
+ IP L+K ++ +S
Sbjct: 132 ASKACIPYLKKSKVAHILNIS 152
>gi|223646115 short chain dehydrogenase/reductase family 16C, member
6 [Homo sapiens]
Length = 323
Score = 35.8 bits (81), Expect = 0.041
Identities = 22/103 (21%), Positives = 52/103 (50%), Gaps = 7/103 (6%)
Query: 27 ETAALAKQLPLKSPSENIFLHIVDLSDPKQIWKFVENFKQEH-KLHVLINNAGCMVNKR- 84
ET LAK+ + +F + D S+ +++++ + ++E + +L+NNA + K
Sbjct: 75 ETCRLAKE----KGGKKVFPYTCDCSNRQEVYRVADQVRKEFGDVTILVNNADLVTGKPF 130
Query: 85 -ELTEDGLEKNFAANTLGVYILTTGLIPVLEKEHDPRVITVSS 126
++ + +EK+F N + + +P + K + ++ +SS
Sbjct: 131 LDIPDHMVEKSFLVNAITHFWTCKAFLPAVIKANHGHLVCISS 173
>gi|210032112 hydroxysteroid (17-beta) dehydrogenase 13 isoform B
[Homo sapiens]
Length = 264
Score = 34.7 bits (78), Expect = 0.091
Identities = 18/72 (25%), Positives = 39/72 (54%), Gaps = 2/72 (2%)
Query: 57 IWKFVENFKQEHKLHVLINNAGCMVNKRELT--EDGLEKNFAANTLGVYILTTGLIPVLE 114
+W + K+ + +++NNAG + L+ ++ + K F N LG + +T L+P +
Sbjct: 65 LWDINKVKKEVGDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNILGHFWITKALLPSMM 124
Query: 115 KEHDPRVITVSS 126
+ + ++TV+S
Sbjct: 125 ERNHGHIVTVAS 136
>gi|40807363 epidermal retinal dehydrogenase 2 [Homo sapiens]
Length = 309
Score = 33.9 bits (76), Expect = 0.15
Identities = 27/111 (24%), Positives = 52/111 (46%), Gaps = 14/111 (12%)
Query: 26 EETAALAKQLPLKSPSENIFLHIVDLSDPKQIWKFVENFKQE-HKLHVLINNAGCMVNKR 84
EET +A++ + + + + D S + +++ + K+E + +LINNAG + K+
Sbjct: 78 EETCKMARE----AGATRVHAYTCDCSQKEGVYRVADQVKKEVGDVSILINNAGIVTGKK 133
Query: 85 ------ELTEDGLEKNFAANTLGVYILTTGLIPVLEKEHDPRVITVSSGGM 129
EL E + NF A+ ++ L ++ +H V SS G+
Sbjct: 134 FLDCPDELMEKSFDVNFKAH---LWTYKAFLPAMIANDHGHLVCISSSAGL 181
>gi|7705421 hydroxysteroid (17-beta) dehydrogenase 7 [Homo sapiens]
Length = 341
Score = 32.7 bits (73), Expect = 0.34
Identities = 20/75 (26%), Positives = 34/75 (45%), Gaps = 1/75 (1%)
Query: 70 LHVLINNAGCMVNKRELTEDGLEKNFAANTLGVYILTTGLIPVLEKEHDP-RVITVSSGG 128
+H+ G + ++T DGL++ F N G +IL L P+L +P ++I SS
Sbjct: 114 IHMFSTAEGLLTQGDKITADGLQEVFETNVFGHFILIRELEPLLCHSDNPSQLIWTSSRS 173
Query: 129 MLVQKLNTNDLQSER 143
+ D Q +
Sbjct: 174 ARKSNFSLEDFQHSK 188
>gi|38679977 acetyl-Coenzyme A carboxylase alpha isoform 2 [Homo
sapiens]
Length = 2346
Score = 32.7 bits (73), Expect = 0.34
Identities = 41/141 (29%), Positives = 64/141 (45%), Gaps = 24/141 (17%)
Query: 3 LHVKTLSLMTWRSRFLEESFWSLEETAALAKQLPLKSPSENIFLHIVDLSDPKQIWKFVE 62
LHV +SL S FL SLE L P+ + L+ VD+ + K+V
Sbjct: 637 LHVADVSLRNSVSNFLH----SLERGQVL--------PAHTL-LNTVDVELIYEGVKYVL 683
Query: 63 NF-KQEHKLHVLINNAGCM-VNKRELTEDGLEKNFAANTLGVYI--------LTTG-LIP 111
+Q +V+I N C+ V+ L++ GL ++ ++ Y+ +T G
Sbjct: 684 KVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLLSYDGSSYTTYMKEEVDRYRITIGNKTC 743
Query: 112 VLEKEHDPRVITVSSGGMLVQ 132
V EKE+DP V+ S G L+Q
Sbjct: 744 VFEKENDPSVMRSPSAGKLIQ 764
>gi|38679974 acetyl-Coenzyme A carboxylase alpha isoform 4 [Homo
sapiens]
Length = 2268
Score = 32.7 bits (73), Expect = 0.34
Identities = 41/141 (29%), Positives = 64/141 (45%), Gaps = 24/141 (17%)
Query: 3 LHVKTLSLMTWRSRFLEESFWSLEETAALAKQLPLKSPSENIFLHIVDLSDPKQIWKFVE 62
LHV +SL S FL SLE L P+ + L+ VD+ + K+V
Sbjct: 559 LHVADVSLRNSVSNFLH----SLERGQVL--------PAHTL-LNTVDVELIYEGVKYVL 605
Query: 63 NF-KQEHKLHVLINNAGCM-VNKRELTEDGLEKNFAANTLGVYI--------LTTG-LIP 111
+Q +V+I N C+ V+ L++ GL ++ ++ Y+ +T G
Sbjct: 606 KVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLLSYDGSSYTTYMKEEVDRYRITIGNKTC 665
Query: 112 VLEKEHDPRVITVSSGGMLVQ 132
V EKE+DP V+ S G L+Q
Sbjct: 666 VFEKENDPSVMRSPSAGKLIQ 686
>gi|38679971 acetyl-Coenzyme A carboxylase alpha isoform 3 [Homo
sapiens]
Length = 2288
Score = 32.7 bits (73), Expect = 0.34
Identities = 41/141 (29%), Positives = 64/141 (45%), Gaps = 24/141 (17%)
Query: 3 LHVKTLSLMTWRSRFLEESFWSLEETAALAKQLPLKSPSENIFLHIVDLSDPKQIWKFVE 62
LHV +SL S FL SLE L P+ + L+ VD+ + K+V
Sbjct: 579 LHVADVSLRNSVSNFLH----SLERGQVL--------PAHTL-LNTVDVELIYEGVKYVL 625
Query: 63 NF-KQEHKLHVLINNAGCM-VNKRELTEDGLEKNFAANTLGVYI--------LTTG-LIP 111
+Q +V+I N C+ V+ L++ GL ++ ++ Y+ +T G
Sbjct: 626 KVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLLSYDGSSYTTYMKEEVDRYRITIGNKTC 685
Query: 112 VLEKEHDPRVITVSSGGMLVQ 132
V EKE+DP V+ S G L+Q
Sbjct: 686 VFEKENDPSVMRSPSAGKLIQ 706
>gi|38679967 acetyl-Coenzyme A carboxylase alpha isoform 2 [Homo
sapiens]
Length = 2346
Score = 32.7 bits (73), Expect = 0.34
Identities = 41/141 (29%), Positives = 64/141 (45%), Gaps = 24/141 (17%)
Query: 3 LHVKTLSLMTWRSRFLEESFWSLEETAALAKQLPLKSPSENIFLHIVDLSDPKQIWKFVE 62
LHV +SL S FL SLE L P+ + L+ VD+ + K+V
Sbjct: 637 LHVADVSLRNSVSNFLH----SLERGQVL--------PAHTL-LNTVDVELIYEGVKYVL 683
Query: 63 NF-KQEHKLHVLINNAGCM-VNKRELTEDGLEKNFAANTLGVYI--------LTTG-LIP 111
+Q +V+I N C+ V+ L++ GL ++ ++ Y+ +T G
Sbjct: 684 KVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLLSYDGSSYTTYMKEEVDRYRITIGNKTC 743
Query: 112 VLEKEHDPRVITVSSGGMLVQ 132
V EKE+DP V+ S G L+Q
Sbjct: 744 VFEKENDPSVMRSPSAGKLIQ 764
>gi|38679960 acetyl-Coenzyme A carboxylase alpha isoform 1 [Homo
sapiens]
Length = 2383
Score = 32.7 bits (73), Expect = 0.34
Identities = 41/141 (29%), Positives = 64/141 (45%), Gaps = 24/141 (17%)
Query: 3 LHVKTLSLMTWRSRFLEESFWSLEETAALAKQLPLKSPSENIFLHIVDLSDPKQIWKFVE 62
LHV +SL S FL SLE L P+ + L+ VD+ + K+V
Sbjct: 674 LHVADVSLRNSVSNFLH----SLERGQVL--------PAHTL-LNTVDVELIYEGVKYVL 720
Query: 63 NF-KQEHKLHVLINNAGCM-VNKRELTEDGLEKNFAANTLGVYI--------LTTG-LIP 111
+Q +V+I N C+ V+ L++ GL ++ ++ Y+ +T G
Sbjct: 721 KVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLLSYDGSSYTTYMKEEVDRYRITIGNKTC 780
Query: 112 VLEKEHDPRVITVSSGGMLVQ 132
V EKE+DP V+ S G L+Q
Sbjct: 781 VFEKENDPSVMRSPSAGKLIQ 801
>gi|154800453 tastin isoform 1 [Homo sapiens]
Length = 778
Score = 32.0 bits (71), Expect = 0.59
Identities = 18/55 (32%), Positives = 26/55 (47%)
Query: 165 RWAQGHPAIHFSSMHPGWADTPDRNEQELRKVVGEAQTASPLPRFLEIMMHEGKC 219
+WA ++ FSS HP A P + Q LR G+A ++ PR L + C
Sbjct: 664 QWAPATTSLIFSSQHPLCASPPICSLQSLRPPAGQAGLSNLAPRTLALRERLKSC 718
>gi|22507405 short chain dehydrogenase/reductase family 9C, member 7
[Homo sapiens]
Length = 313
Score = 30.4 bits (67), Expect = 1.7
Identities = 23/90 (25%), Positives = 42/90 (46%), Gaps = 4/90 (4%)
Query: 42 ENIFLHIVDLSDPKQIWKFVENFKQEHKLHVLINNAGCMVNKRE---LTEDGLEKNFAAN 98
+ L + K ++V + E L L+NNAG + LT+D K N
Sbjct: 74 QTTLLDVTKSESIKAAAQWVRDKVGEQGLWALVNNAGVGLPSGPNEWLTKDDFVKVINVN 133
Query: 99 TLGVYILTTGLIPVLEKEHDPRVITVSSGG 128
+G+ +T ++P++++ RV+ +SS G
Sbjct: 134 LVGLIEVTLHMLPMVKRARG-RVVNMSSSG 162
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.132 0.409
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,220,655
Number of Sequences: 37866
Number of extensions: 520458
Number of successful extensions: 1210
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 22
Number of HSP's that attempted gapping in prelim test: 1178
Number of HSP's gapped (non-prelim): 48
length of query: 271
length of database: 18,247,518
effective HSP length: 101
effective length of query: 170
effective length of database: 14,423,052
effective search space: 2451918840
effective search space used: 2451918840
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.