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Search of human proteins with 72534716
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|72534716 coiled-coil domain containing 90A [Homo sapiens]
(359 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|72534716 coiled-coil domain containing 90A [Homo sapiens] 697 0.0
gi|20149663 coiled-coil domain containing 90B [Homo sapiens] 228 6e-60
gi|190341068 forkhead-associated (FHA) phosphopeptide binding do... 42 0.001
gi|81295816 nasopharyngeal epithelium specific protein 1 [Homo s... 42 0.001
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 40 0.002
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] 38 0.012
gi|55770834 centromere protein F [Homo sapiens] 38 0.016
gi|7657138 golgi integral membrane protein 4 [Homo sapiens] 37 0.021
gi|169178850 PREDICTED: similar to coiled-coil domain containing... 37 0.027
gi|31542661 transmembrane protein 57 [Homo sapiens] 37 0.027
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 37 0.027
gi|58530842 desmoplakin isoform II [Homo sapiens] 37 0.036
gi|15431310 keratin 14 [Homo sapiens] 37 0.036
gi|151101151 coiled-coil domain containing 2 isoform b [Homo sap... 36 0.047
gi|151101140 coiled-coil domain containing 2 isoform a [Homo sap... 36 0.047
gi|151105223 coiled-coil domain containing 2 isoform a [Homo sap... 36 0.047
gi|151105229 coiled-coil domain containing 2 isoform a [Homo sap... 36 0.047
gi|30089940 Golgi autoantigen, golgin subfamily a, 3 [Homo sapiens] 36 0.061
gi|149363642 coiled-coil domain containing 144A [Homo sapiens] 35 0.080
gi|215490011 small inducible cytokine subfamily E, member 1 isof... 35 0.10
gi|215490009 small inducible cytokine subfamily E, member 1 isof... 35 0.10
gi|45006986 small inducible cytokine subfamily E, member 1 isofo... 35 0.10
gi|239750966 PREDICTED: hypothetical protein XP_002347633 [Homo ... 35 0.10
gi|239749325 PREDICTED: hypothetical protein [Homo sapiens] 35 0.10
gi|239745372 PREDICTED: hypothetical protein XP_002343483 [Homo ... 35 0.10
gi|239741653 PREDICTED: hypothetical protein XP_002342271 [Homo ... 35 0.10
gi|239509122 PREDICTED: hypothetical protein [Homo sapiens] 35 0.10
gi|4506967 v-ski sarcoma viral oncogene homolog [Homo sapiens] 35 0.14
gi|239747109 PREDICTED: hypothetical protein XP_002344496 [Homo ... 35 0.14
gi|126362971 serine/threonine kinase 10 [Homo sapiens] 35 0.14
>gi|72534716 coiled-coil domain containing 90A [Homo sapiens]
Length = 359
Score = 697 bits (1800), Expect = 0.0
Identities = 359/359 (100%), Positives = 359/359 (100%)
Query: 1 MDCGSVGGQRTQRLPGRQRLLFLPVGLSGRPGGSETSARRCLSALSDGLGALRPRAPAAR 60
MDCGSVGGQRTQRLPGRQRLLFLPVGLSGRPGGSETSARRCLSALSDGLGALRPRAPAAR
Sbjct: 1 MDCGSVGGQRTQRLPGRQRLLFLPVGLSGRPGGSETSARRCLSALSDGLGALRPRAPAAR 60
Query: 61 GGVSRASPLLLLLLVPSPRLAAAAPRRQLGDWERSRLGYAAPPAGRSSAWRCSPGVAAAA 120
GGVSRASPLLLLLLVPSPRLAAAAPRRQLGDWERSRLGYAAPPAGRSSAWRCSPGVAAAA
Sbjct: 61 GGVSRASPLLLLLLVPSPRLAAAAPRRQLGDWERSRLGYAAPPAGRSSAWRCSPGVAAAA 120
Query: 121 GALPQYHGPAPALVSCRRELSLSAGSLQLERKRRDFTSSGSRKLYFDTHALVCLLEDNGF 180
GALPQYHGPAPALVSCRRELSLSAGSLQLERKRRDFTSSGSRKLYFDTHALVCLLEDNGF
Sbjct: 121 GALPQYHGPAPALVSCRRELSLSAGSLQLERKRRDFTSSGSRKLYFDTHALVCLLEDNGF 180
Query: 181 ATQQAEIIVSALVKILEANMDIVYKDMVTKMQQEITFQQVMSQIANVKKDMIILEKSEFS 240
ATQQAEIIVSALVKILEANMDIVYKDMVTKMQQEITFQQVMSQIANVKKDMIILEKSEFS
Sbjct: 181 ATQQAEIIVSALVKILEANMDIVYKDMVTKMQQEITFQQVMSQIANVKKDMIILEKSEFS 240
Query: 241 ALRAENEKIKLELHQLKQQVMDEVIKVRTDTKLDFNLEKSRVKELYSLNEKKLLELRTEI 300
ALRAENEKIKLELHQLKQQVMDEVIKVRTDTKLDFNLEKSRVKELYSLNEKKLLELRTEI
Sbjct: 241 ALRAENEKIKLELHQLKQQVMDEVIKVRTDTKLDFNLEKSRVKELYSLNEKKLLELRTEI 300
Query: 301 VALHAQQDRALTQTDRKIETEVAGLKTMLESHKLDNIKYLAGSIFTCLTVALGFYRLWI 359
VALHAQQDRALTQTDRKIETEVAGLKTMLESHKLDNIKYLAGSIFTCLTVALGFYRLWI
Sbjct: 301 VALHAQQDRALTQTDRKIETEVAGLKTMLESHKLDNIKYLAGSIFTCLTVALGFYRLWI 359
>gi|20149663 coiled-coil domain containing 90B [Homo sapiens]
Length = 254
Score = 228 bits (581), Expect = 6e-60
Identities = 117/229 (51%), Positives = 160/229 (69%), Gaps = 3/229 (1%)
Query: 130 APALVSCRRELSLSAGSLQLERKRRDFTSSGSRKLYFDTHALVCLLEDNGFATQQAEIIV 189
+PAL RRE + +R+ D T RKL FDTHALV LE +GF QAE IV
Sbjct: 28 SPAL---RREFFTTTTKEGYDRRPVDITPLEQRKLTFDTHALVQDLETHGFDKTQAETIV 84
Query: 190 SALVKILEANMDIVYKDMVTKMQQEITFQQVMSQIANVKKDMIILEKSEFSALRAENEKI 249
SAL + ++D +YK+MVT+ QQEIT QQ+M+ + ++KDM+ILEKSEF+ LRAENEK+
Sbjct: 85 SALTALSNVSLDTIYKEMVTQAQQEITVQQLMAHLDAIRKDMVILEKSEFANLRAENEKM 144
Query: 250 KLELHQLKQQVMDEVIKVRTDTKLDFNLEKSRVKELYSLNEKKLLELRTEIVALHAQQDR 309
K+EL Q+KQQ+M E ++R D KLD NLE+SRV ++++ EK+L+E TE Q
Sbjct: 145 KIELDQVKQQLMHETSRIRADNKLDINLERSRVTDMFTDQEKQLMETTTEFTKKDTQTKS 204
Query: 310 ALTQTDRKIETEVAGLKTMLESHKLDNIKYLAGSIFTCLTVALGFYRLW 358
+++T KI+ E+A LKT++ES+KL+ I+YLA S+FTCL +ALGFYR W
Sbjct: 205 IISETSNKIDAEIASLKTLMESNKLETIRYLAASVFTCLAIALGFYRFW 253
>gi|190341068 forkhead-associated (FHA) phosphopeptide binding domain
1 [Homo sapiens]
Length = 1412
Score = 41.6 bits (96), Expect = 0.001
Identities = 52/201 (25%), Positives = 95/201 (47%), Gaps = 22/201 (10%)
Query: 125 QYHGPAPALVSCRRELSLSAGSL-QLERKRRDFTSSGSRKLYFDTHALVCLLEDNGFATQ 183
Q HG ++ + ++ A ++ LE K + T + + L+DN A +
Sbjct: 914 QRHGFEEEIMEYKEQIKQHAQTIVSLEEKLQKVTQHHKK-----IEGEIATLKDNDPAPK 968
Query: 184 QAEIIVSALVKILEANM-DIVYKDMVTKM---QQEITFQQVMSQIANVKKDMIILEKSEF 239
+ + + E++ D+ Y+ ++ + Q+EI QQ + I ++KD+ S
Sbjct: 969 EERPQDPLVAPMTESSAKDMAYEHLIDDLLAAQKEILSQQEV--IMKLRKDLTEAH-SRM 1025
Query: 240 SALRAE-NEKIKLELHQLKQQVMDEVIKVRTDTKLDFNLEKSRVKELYSLNEKKLLELRT 298
S LR E NEK K+EL Q V+ V+ +K + ++ K ++ ++ SL EKK EL+
Sbjct: 1026 SDLRGELNEKQKMELEQ-------NVVLVQQQSK-ELSVLKEKMAQMSSLVEKKDRELKA 1077
Query: 299 EIVALHAQQDRALTQTDRKIE 319
AL A Q++ Q + + E
Sbjct: 1078 LEEALRASQEKHRLQLNTEKE 1098
>gi|81295816 nasopharyngeal epithelium specific protein 1 [Homo
sapiens]
Length = 551
Score = 41.6 bits (96), Expect = 0.001
Identities = 47/203 (23%), Positives = 87/203 (42%), Gaps = 41/203 (20%)
Query: 148 QLERKRRDFTSSGSRKLYFDTHALVCLLEDNGFATQQAEIIVSALVKILEANMDIVYKDM 207
+LERKRR+ G R++ + E+ +Q E +++ +E + KDM
Sbjct: 245 ELERKRREERIRGRRQI---VEQMEKNQEERSLLAEQREQEKEQMLEYMEQLQEEDLKDM 301
Query: 208 VTKMQQEITFQQVMSQIANVKKDMIILEKSEFSALRAENEKIKLEL---HQLKQQVMDEV 264
+ QQ++ Q +E + EN+K K EL +L Q++ E
Sbjct: 302 ERRQQQKLKMQ------------------AEIKRINDENQKQKAELLAQEKLADQMVMEF 343
Query: 265 IKVRTDTKLDFNLEKSRV-----KELYSLN--EKKLLELRTEIVALHAQQDRALTQTD-- 315
K + + +F E+ R+ KE+ L ++K + + E AL A++++ + +
Sbjct: 344 TKKKMAREAEFEAEQERIRREKEKEIARLRAMQEKAQDYQAEQDALRAKRNQEVADREWR 403
Query: 316 --------RKIETEVAGLKTMLE 330
+K+ETE K+ LE
Sbjct: 404 RKEKENARKKMETEAELRKSRLE 426
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 40.4 bits (93), Expect = 0.002
Identities = 35/134 (26%), Positives = 65/134 (48%), Gaps = 11/134 (8%)
Query: 214 EITFQQVMSQIANVKKDMIIL--EKSEFSA----LRAENEKIKLELHQLKQQVMDEVIKV 267
EI Q+ ++A +K+ +++ EK E + L+ E K L++L++Q+ + V
Sbjct: 1063 EIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHV 1122
Query: 268 RT----DTKLDFNLEKSRVKELYSLNEKKLL-ELRTEIVALHAQQDRALTQTDRKIETEV 322
+ +TKL +LEK V SL E L E E+ L + R +++ K++T
Sbjct: 1123 NSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTD 1182
Query: 323 AGLKTMLESHKLDN 336
+++ SH+ N
Sbjct: 1183 EEFQSLKSSHEKSN 1196
>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
Length = 1946
Score = 38.1 bits (87), Expect = 0.012
Identities = 23/87 (26%), Positives = 43/87 (49%), Gaps = 9/87 (10%)
Query: 242 LRAENEKIKLELHQLKQQV---------MDEVIKVRTDTKLDFNLEKSRVKELYSLNEKK 292
LR EN+ ++ E+ L QV M++V K+ + K + + + NE K
Sbjct: 1510 LRRENKNLQEEISNLTNQVREGTKNLTEMEKVKKLIEEEKTEVQVTLEETEGALERNESK 1569
Query: 293 LLELRTEIVALHAQQDRALTQTDRKIE 319
+L + E++ A+ +R L++ D +IE
Sbjct: 1570 ILHFQLELLEAKAELERKLSEKDEEIE 1596
Score = 32.3 bits (72), Expect = 0.67
Identities = 46/211 (21%), Positives = 92/211 (43%), Gaps = 11/211 (5%)
Query: 121 GALPQYHGPAPALVSCRRELSLSAGSLQLERKRRDFTSSGSRKLYFDTHALVCLLEDNGF 180
GAL Q A ++C REL G+L+L R+ + S R L + L
Sbjct: 1048 GALEQER---KARMNCERELHKLEGNLKLNRESMENLESSQRHLAEELRKKELELSQMNS 1104
Query: 181 ATQQAEIIVSALVKILEANMDIVYKDMVTKMQQEITFQQVMS-QIANVKKDMIILEKSEF 239
+ + +V+ L K ++ + KD+ K++ E T + M + A++ +D+ L +E
Sbjct: 1105 KVENEKGLVAQLQKTVK-ELQTQIKDLKEKLEAERTTRAKMERERADLTQDLADL--NER 1161
Query: 240 SALRAENEKIKLELHQLKQQVMDEVIKVRTDTKLDFNLEKSRVKELYSLNEKKLLELRTE 299
+ +LE+ + ++ ++ + + L F + +K+ ++ L EL +
Sbjct: 1162 LEEVGGSSLAQLEITKKQETKFQKLHRDMEEATLHFETTSASLKKRHA---DSLAELEGQ 1218
Query: 300 IVALHAQQDRALTQTDRKIETEVAGLKTMLE 330
+ L Q + L + ++ EV L T +E
Sbjct: 1219 VENLQ-QVKQKLEKDKSDLQLEVDDLLTRVE 1248
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 37.7 bits (86), Expect = 0.016
Identities = 40/193 (20%), Positives = 94/193 (48%), Gaps = 31/193 (16%)
Query: 176 EDNGFATQQAEIIVSALVKILEANMDIVYK---------DMVTKMQQEITFQQVMSQIAN 226
++N ++ ++ V+ L K + + D++ K D ++K ++E + ++S +
Sbjct: 547 QENSLTLEKLKLAVADLEKQRDCSQDLLKKREHHIEQLNDKLSKTEKES--KALLSALEL 604
Query: 227 VKKDMIIL--EKSEFSALRAENEKIKLELHQLKQQVMDEVIKVRTDTKL------DFN-- 276
KK+ L EK+ FS ++ENEK+ ++ K+ + ++ + T K ++N
Sbjct: 605 KKKEYEELKEEKTLFSCWKSENEKLLTQMESEKENLQSKINHLETCLKTQQIKSHEYNER 664
Query: 277 ---LEKSR------VKELYSLNEKKLLELRTEIVA-LHAQQDRALTQTDRKIETEVAGLK 326
LE R ++ L+++ + K +E+ T+ +A + QQ + + E E LK
Sbjct: 665 VRTLEMDRENLSVEIRNLHNVLDSKSVEVETQKLAYMELQQKAEFSDQKHQKEIENMCLK 724
Query: 327 TMLESHKLDNIKY 339
T + +++++++
Sbjct: 725 TSQLTGQVEDLEH 737
Score = 32.3 bits (72), Expect = 0.67
Identities = 26/110 (23%), Positives = 56/110 (50%), Gaps = 10/110 (9%)
Query: 212 QQEITFQQVMSQIANVKKDMIILEKSE----FSALRAENEKIKLELHQLKQQVMDEVIKV 267
+QE+T + QI + + S L+A+N++++ ++++L+ ++ ++
Sbjct: 249 EQEVTPSRSTLQIGKRDANSSFFDNSSSPHLLDQLKAQNQELRNKINELELRLQGHEKEM 308
Query: 268 RTDT----KLDFNLEKSRVKELYSLNEKKLLELRTEIVALHAQQDRALTQ 313
+ +L LEK++V+ + EK L + R E+V AQ D+A T+
Sbjct: 309 KGQVNKFQELQLQLEKAKVELIEK--EKVLNKCRDELVRTTAQYDQASTK 356
Score = 31.2 bits (69), Expect = 1.5
Identities = 22/97 (22%), Positives = 54/97 (55%), Gaps = 11/97 (11%)
Query: 208 VTKMQQEITFQQ-----VMSQIANVKKDMIILEKSEFSALRAENEKIKLELHQLKQQVMD 262
++K+Q++ + Q +S + N +K++ +L + +AE +++K H L+ + +
Sbjct: 885 ISKLQEDTSAHQNVVAETLSALENKEKELQLLN-DKVETEQAEIQELKKSNHLLEDSLKE 943
Query: 263 EVIKVRTDTKLDFNLEKSRVKELYSLNEKKLLELRTE 299
+++ ++T +LEK + + SLN++++ EL E
Sbjct: 944 --LQLLSET---LSLEKKEMSSIISLNKREIEELTQE 975
>gi|7657138 golgi integral membrane protein 4 [Homo sapiens]
Length = 696
Score = 37.4 bits (85), Expect = 0.021
Identities = 35/155 (22%), Positives = 71/155 (45%), Gaps = 24/155 (15%)
Query: 196 LEANMDIVYKDMVTKMQQEITFQQVMSQIANVKKDMIILE--------------KSEFSA 241
L A + +VY+ + + E + Q+ + K+D ++ + S +SA
Sbjct: 57 LSAQLQVVYEH---RSRLEKSLQKERLEHKKAKEDFLVYKLEAQETLNKGRQDSNSRYSA 113
Query: 242 LRAENEKIKLELHQLKQQVMD---EVIKVRTDTKLDFNLEKSRVKELYSLNEKKLLELRT 298
L +++ +K + +LK+Q D E K D FN K + +L E++L +L+
Sbjct: 114 LNVQHQMLKSQHEELKKQHSDLEEEHRKQGEDFSRTFNDHKQKYLQLQQEKEQELSKLKE 173
Query: 299 EIVALHAQQDRALTQTDRKIETEVAGLKTMLESHK 333
+ L +++R L + + I T++ +K + HK
Sbjct: 174 TVYNLR-EENRQLRKAHQDIHTQLQDVK---QQHK 204
>gi|169178850 PREDICTED: similar to coiled-coil domain containing 29
[Homo sapiens]
Length = 197
Score = 37.0 bits (84), Expect = 0.027
Identities = 31/137 (22%), Positives = 72/137 (52%), Gaps = 5/137 (3%)
Query: 193 VKILEANMDIVYKDMVTKMQQEITFQQ-VMSQIANVKKDMIILEKSEFSALRAENEKIKL 251
+K + MDI+ K + K + ++ V S+ N+ KD ++++ S + + E KL
Sbjct: 20 LKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECEKL 79
Query: 252 ELHQLKQQVMDEVIKVRTDTKLDFNLEKSRVKELYSLNEKKLLELRTEIVALHAQQD-RA 310
E +Q + + +E++ ++T + + +E S+++E S +++ ++ ++ +H Q +
Sbjct: 80 EENQ--KMLEEEILNLKTHME-NSMVELSKLQEYKSELDERAMQAVEKLKEIHLQMELDC 136
Query: 311 LTQTDRKIETEVAGLKT 327
+ Q R+ + VA L T
Sbjct: 137 VEQIIRETKRTVAVLDT 153
>gi|31542661 transmembrane protein 57 [Homo sapiens]
Length = 664
Score = 37.0 bits (84), Expect = 0.027
Identities = 44/158 (27%), Positives = 73/158 (46%), Gaps = 13/158 (8%)
Query: 191 ALVKILEANMDIVYKDMVTKMQQEITFQQVMSQIANVKKDMIILEKSEFSALRAENEKIK 250
ALV+ LE ++ + D+ Q E + +S +++ ++ + +SE LR ENE ++
Sbjct: 382 ALVR-LEQDIKKLKADLQASRQVEQELRSQISSLSSTERGI----RSEMGQLRQENELLQ 436
Query: 251 LELH---QLKQQVMDEVIKVRTDTKLDFNLEKSRVKELYSLNEKKLLELRT--EIVALHA 305
+LH Q+KQ+ + ++ K + K+L ++K LE T VA A
Sbjct: 437 NKLHNAVQMKQKDKQNISQLEKKLKAEQEARSFVEKQLMEEKKRKKLEEATAARAVAFAA 496
Query: 306 QQDRALTQT--DRKIETEVAGLK-TMLESHKLDNIKYL 340
T+T +R E E G K TM K D I+ L
Sbjct: 497 ASRGECTETLRNRIRELEAEGKKLTMDMKVKEDQIREL 534
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 37.0 bits (84), Expect = 0.027
Identities = 33/149 (22%), Positives = 71/149 (47%), Gaps = 20/149 (13%)
Query: 197 EANMDIVYKDMVTKMQQEITFQQ---VMSQIANVKKDMIILEKSE------FSALRAENE 247
+ N I KD K E+ QQ + ++ A +++ + E++ F+AL+ E +
Sbjct: 2539 DLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQ 2598
Query: 248 KIKLELHQLK---QQVMDEVIKVRTDTKLDFNLEKSRVKE--------LYSLNEKKLLEL 296
+ E+ LK Q+ +V ++ + L + +VKE L+S ++K++ EL
Sbjct: 2599 DLSKEIESLKVSISQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAEL 2658
Query: 297 RTEIVALHAQQDRALTQTDRKIETEVAGL 325
E+V + + + + + + K++ E+ L
Sbjct: 2659 EEELVCVQKEAAKKVGEIEDKLKKELKHL 2687
Score = 31.2 bits (69), Expect = 1.5
Identities = 40/154 (25%), Positives = 73/154 (47%), Gaps = 17/154 (11%)
Query: 189 VSALVKILEANMDIVYKDMVTKMQQEITFQQVMSQIANVKKDM-------IILEKSEFSA 241
+SAL + ++A + + ++ EIT + + + + KK ++L+ ++ A
Sbjct: 2035 ISALERTVKA---LEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEA 2091
Query: 242 LR--AENEKIKLELHQLKQQVMDEVIKVRTDTKLDFNLEKSRVKELYSLN--EKKLLELR 297
R A+N K+K EL K+ V ++ + D L+ LE++ K L ++KL LR
Sbjct: 2092 ARVLADNLKLKKELQSNKESVKSQM--KQKDEDLERRLEQAEEKHLKEKKNMQEKLDALR 2149
Query: 298 TEIVALHAQQDRALTQTDRKIETEVAGLKTMLES 331
E V L + + T K + EV L+ L+S
Sbjct: 2150 REKVHLE-ETIGEIQVTLNKKDKEVQQLQENLDS 2182
>gi|58530842 desmoplakin isoform II [Homo sapiens]
Length = 2272
Score = 36.6 bits (83), Expect = 0.036
Identities = 46/198 (23%), Positives = 80/198 (40%), Gaps = 28/198 (14%)
Query: 139 ELSLSAGSLQLERKRRDFTSSGSRKLYFDTHALVC---LLEDNGFATQQAEIIVSALVKI 195
E ++ ++ER R G+RK ++ + E TQ + S LVKI
Sbjct: 1161 EKAIKEKEYEIERLRVLLQEEGTRKREYENELAKASNRIQESKNQCTQVVQERESLLVKI 1220
Query: 196 LEANMDIVYKDMVTKMQQEITFQQVMSQIANVKKDMIILEKSEFSALRAENEKIKLELHQ 255
D K + +++ E+ N K + E L E ++I+ +L+Q
Sbjct: 1221 KVLEQD---KARLQRLEDEL----------NRAKSTLEAETRVKQRLECEKQQIQNDLNQ 1267
Query: 256 LKQQVMDEVIKVRTDTKLDFNLEKSRVKELYSLNEKKLLELRTEIVALHAQQDRALTQTD 315
K Q + +R K++ EKS E++ LR+EI L A+ R +
Sbjct: 1268 WKTQYSRKEEAIR---KIESEREKS---------EREKNSLRSEIERLQAEIKRIEERCR 1315
Query: 316 RKIETEVAGLKTMLESHK 333
RK+E ++ LE+ +
Sbjct: 1316 RKLEDSTRETQSQLETER 1333
>gi|15431310 keratin 14 [Homo sapiens]
Length = 472
Score = 36.6 bits (83), Expect = 0.036
Identities = 31/147 (21%), Positives = 74/147 (50%), Gaps = 9/147 (6%)
Query: 204 YKDMVTKMQQE-----ITFQQVMSQIANVKKDMIILEKSEFSALRAENEKIKLELHQLKQ 258
Y+ M K +++ T + +++ +++ KSE S LR + +++EL Q +
Sbjct: 291 YEKMAEKNRKDAEEWFFTKTEELNREVATNSELVQSGKSEISELRRTMQNLEIEL-QSQL 349
Query: 259 QVMDEVIKVRTDTKLDFNLEKSRVKELYSLNEKKLLELRTEIVALHAQQDRALTQTDRKI 318
+ + +TK + ++ ++++E+ E++L +LR E+ + Q+ + L ++
Sbjct: 350 SMKASLENSLEETKGRYCMQLAQIQEMIGSVEEQLAQLRCEMEQQN-QEYKILLDVKTRL 408
Query: 319 ETEVAGLKTMLESH--KLDNIKYLAGS 343
E E+A + +LE L + ++ +GS
Sbjct: 409 EQEIATYRRLLEGEDAHLSSSQFSSGS 435
>gi|151101151 coiled-coil domain containing 2 isoform b [Homo
sapiens]
Length = 372
Score = 36.2 bits (82), Expect = 0.047
Identities = 33/142 (23%), Positives = 68/142 (47%), Gaps = 15/142 (10%)
Query: 199 NMDIVYKDMVTKMQQ----EITFQQVMSQIANVKKDMIILEKSEFSALRAENEKIKLELH 254
++D+++ + K +Q E +Q ++ K+M + ++ ++ NEK+ EL
Sbjct: 186 SLDVIFTERQAKEKQIRSVEEEIEQEKQATDDIIKNMSFENQVKYLEMKTTNEKLLQELD 245
Query: 255 QLKQQVMDEVIKVRTDTKLDFNLEKSRVKELYSLNEKKLLELRTEIVALHAQQDRALTQT 314
L+QQ+ + +K + L+ + S+VK+ L +KL EL + H Q +
Sbjct: 246 TLQQQLDSQNMKKES---LEAEIAHSQVKQEAVLLHEKLYELES-----HRDQ---MIAE 294
Query: 315 DRKIETEVAGLKTMLESHKLDN 336
D+ I + + + +L+ K DN
Sbjct: 295 DKSIGSPMEEREKLLKQIKDDN 316
>gi|151101140 coiled-coil domain containing 2 isoform a [Homo
sapiens]
Length = 600
Score = 36.2 bits (82), Expect = 0.047
Identities = 33/142 (23%), Positives = 68/142 (47%), Gaps = 15/142 (10%)
Query: 199 NMDIVYKDMVTKMQQ----EITFQQVMSQIANVKKDMIILEKSEFSALRAENEKIKLELH 254
++D+++ + K +Q E +Q ++ K+M + ++ ++ NEK+ EL
Sbjct: 186 SLDVIFTERQAKEKQIRSVEEEIEQEKQATDDIIKNMSFENQVKYLEMKTTNEKLLQELD 245
Query: 255 QLKQQVMDEVIKVRTDTKLDFNLEKSRVKELYSLNEKKLLELRTEIVALHAQQDRALTQT 314
L+QQ+ + +K + L+ + S+VK+ L +KL EL + H Q +
Sbjct: 246 TLQQQLDSQNMKKES---LEAEIAHSQVKQEAVLLHEKLYELES-----HRDQ---MIAE 294
Query: 315 DRKIETEVAGLKTMLESHKLDN 336
D+ I + + + +L+ K DN
Sbjct: 295 DKSIGSPMEEREKLLKQIKDDN 316
>gi|151105223 coiled-coil domain containing 2 isoform a [Homo
sapiens]
Length = 600
Score = 36.2 bits (82), Expect = 0.047
Identities = 33/142 (23%), Positives = 68/142 (47%), Gaps = 15/142 (10%)
Query: 199 NMDIVYKDMVTKMQQ----EITFQQVMSQIANVKKDMIILEKSEFSALRAENEKIKLELH 254
++D+++ + K +Q E +Q ++ K+M + ++ ++ NEK+ EL
Sbjct: 186 SLDVIFTERQAKEKQIRSVEEEIEQEKQATDDIIKNMSFENQVKYLEMKTTNEKLLQELD 245
Query: 255 QLKQQVMDEVIKVRTDTKLDFNLEKSRVKELYSLNEKKLLELRTEIVALHAQQDRALTQT 314
L+QQ+ + +K + L+ + S+VK+ L +KL EL + H Q +
Sbjct: 246 TLQQQLDSQNMKKES---LEAEIAHSQVKQEAVLLHEKLYELES-----HRDQ---MIAE 294
Query: 315 DRKIETEVAGLKTMLESHKLDN 336
D+ I + + + +L+ K DN
Sbjct: 295 DKSIGSPMEEREKLLKQIKDDN 316
>gi|151105229 coiled-coil domain containing 2 isoform a [Homo
sapiens]
Length = 600
Score = 36.2 bits (82), Expect = 0.047
Identities = 33/142 (23%), Positives = 68/142 (47%), Gaps = 15/142 (10%)
Query: 199 NMDIVYKDMVTKMQQ----EITFQQVMSQIANVKKDMIILEKSEFSALRAENEKIKLELH 254
++D+++ + K +Q E +Q ++ K+M + ++ ++ NEK+ EL
Sbjct: 186 SLDVIFTERQAKEKQIRSVEEEIEQEKQATDDIIKNMSFENQVKYLEMKTTNEKLLQELD 245
Query: 255 QLKQQVMDEVIKVRTDTKLDFNLEKSRVKELYSLNEKKLLELRTEIVALHAQQDRALTQT 314
L+QQ+ + +K + L+ + S+VK+ L +KL EL + H Q +
Sbjct: 246 TLQQQLDSQNMKKES---LEAEIAHSQVKQEAVLLHEKLYELES-----HRDQ---MIAE 294
Query: 315 DRKIETEVAGLKTMLESHKLDN 336
D+ I + + + +L+ K DN
Sbjct: 295 DKSIGSPMEEREKLLKQIKDDN 316
>gi|30089940 Golgi autoantigen, golgin subfamily a, 3 [Homo sapiens]
Length = 1498
Score = 35.8 bits (81), Expect = 0.061
Identities = 49/211 (23%), Positives = 87/211 (41%), Gaps = 18/211 (8%)
Query: 137 RRELSLSAGSLQLERKRRDFTSSGSRKLYFDTHALVCLLEDNGFATQQAEIIVSALVKI- 195
R+ ++ G LQ +K RD + + L FD +V + E N +Q E + K
Sbjct: 912 RQHMADLEGHLQSAQKERDEMETHLQSLQFDKEQMVAVTEANEALKKQIEELQQEARKAI 971
Query: 196 ---------LEANMDIVYKDMVTKMQQEITFQQVMSQIANVKKDMIILEKSEFSALRAE- 245
L +++ K+M TK + ++S+ +E LRA+
Sbjct: 972 TEQKQKMRRLGSDLTSAQKEMKTKHKAYENAVGILSRRLQEALAAKEAADAELGQLRAQG 1031
Query: 246 -NEKIKLELHQLKQQVMDEVIKVRTDTKLDFNLEKSRVKELYSLNEKKLLELRTEIVAL- 303
+ L LH+ Q + E+ V L LEK ++E+ +L ++L E R +++ L
Sbjct: 1032 GSSDSSLALHERIQALEAELQAVSHSKTL---LEK-ELQEVIALTSQELEESREKVLELE 1087
Query: 304 -HAQQDRALTQTDRKIETEVAGLKTMLESHK 333
Q+ R + +++E L LE K
Sbjct: 1088 DELQESRGFRKKIKRLEESNKKLALELEHEK 1118
>gi|149363642 coiled-coil domain containing 144A [Homo sapiens]
Length = 1427
Score = 35.4 bits (80), Expect = 0.080
Identities = 49/217 (22%), Positives = 102/217 (47%), Gaps = 33/217 (15%)
Query: 141 SLSAGSLQLERKRRDFTSSGSRKLYFDTHALVCLLEDNGFATQQAEI--IVSALVKILEA 198
+L SL LER +RD + + +K +T + + +Q+++ ++ + E
Sbjct: 992 ALGRESLILERVQRDLSQTQCQKK--ETEQM--------YQIEQSKLKKYIAKQESVEER 1041
Query: 199 NMDIVYKDMVTKMQQEITFQQVMSQIANVKKDMIILEKSEFSA---LRAENEKIKLELHQ 255
+ ++M+ + Q + ++ SQ +K ++ SA L+AE+EK L L +
Sbjct: 1042 LSQLQSENMLLRQQLDDAHKKANSQ----EKTSSTIQDQFHSAAKNLQAESEKQILSLQE 1097
Query: 256 LKQQVMDEV--IKVRTD--------TKLDFNLEKSRVKE--LYSLNEKKLLELRTEIVAL 303
+++MDE +K R D K+D + V L+ E ++L+L+ + ++
Sbjct: 1098 KNKELMDEYNHLKERMDQCEKEKAGRKIDLTEAQETVPSRCLHLDAENEVLQLQQTLFSM 1157
Query: 304 HA--QQDRALTQTDRKIETEVAGLKTMLESHKLDNIK 338
A +Q L + ++++ EV LK+ +E + L+ K
Sbjct: 1158 KAIQKQCETLQKNKKQLKQEVVNLKSYMERNMLERGK 1194
Score = 30.8 bits (68), Expect = 2.0
Identities = 25/108 (23%), Positives = 50/108 (46%), Gaps = 11/108 (10%)
Query: 183 QQAEIIVSALVKILEANMDIVYKDMVTKMQQEITFQQVMSQIANVKKDMIILEKSE---F 239
+QA + LV++ E N + K Q E+T + + S+I+ +K K+E +
Sbjct: 1223 KQAAVSHEQLVQLREDNTTSI------KTQMELTIKDLESEISRIKTSQADFNKTELERY 1276
Query: 240 SALRAENEKIKLELHQLKQQVMDEVIKVRTDTKLDFNLEKSRVKELYS 287
L E K++ L + + + +V T+L E++R + L++
Sbjct: 1277 KELYLEEVKVRESLSNELSRTNEMIAEV--STQLTVEKEQTRSRSLFT 1322
>gi|215490011 small inducible cytokine subfamily E, member 1 isoform
b precursor [Homo sapiens]
Length = 336
Score = 35.0 bits (79), Expect = 0.10
Identities = 22/71 (30%), Positives = 38/71 (53%), Gaps = 2/71 (2%)
Query: 198 ANMDIVYKDMVTKMQQEITFQQVMSQIANVKKDMIILEKS--EFSALRAENEKIKLELHQ 255
AN D V K + K + + + Q ++ K+ IL+ + E LR EN K+K E+ +
Sbjct: 26 ANNDAVLKRLEQKGAEADQIIEYLKQQVSLLKEKAILQATLREEKKLRVENAKLKKEIEE 85
Query: 256 LKQQVMDEVIK 266
LKQ+++ I+
Sbjct: 86 LKQELIQAEIQ 96
>gi|215490009 small inducible cytokine subfamily E, member 1 isoform
a precursor [Homo sapiens]
Length = 312
Score = 35.0 bits (79), Expect = 0.10
Identities = 22/71 (30%), Positives = 38/71 (53%), Gaps = 2/71 (2%)
Query: 198 ANMDIVYKDMVTKMQQEITFQQVMSQIANVKKDMIILEKS--EFSALRAENEKIKLELHQ 255
AN D V K + K + + + Q ++ K+ IL+ + E LR EN K+K E+ +
Sbjct: 2 ANNDAVLKRLEQKGAEADQIIEYLKQQVSLLKEKAILQATLREEKKLRVENAKLKKEIEE 61
Query: 256 LKQQVMDEVIK 266
LKQ+++ I+
Sbjct: 62 LKQELIQAEIQ 72
>gi|45006986 small inducible cytokine subfamily E, member 1 isoform
a precursor [Homo sapiens]
Length = 312
Score = 35.0 bits (79), Expect = 0.10
Identities = 22/71 (30%), Positives = 38/71 (53%), Gaps = 2/71 (2%)
Query: 198 ANMDIVYKDMVTKMQQEITFQQVMSQIANVKKDMIILEKS--EFSALRAENEKIKLELHQ 255
AN D V K + K + + + Q ++ K+ IL+ + E LR EN K+K E+ +
Sbjct: 2 ANNDAVLKRLEQKGAEADQIIEYLKQQVSLLKEKAILQATLREEKKLRVENAKLKKEIEE 61
Query: 256 LKQQVMDEVIK 266
LKQ+++ I+
Sbjct: 62 LKQELIQAEIQ 72
>gi|239750966 PREDICTED: hypothetical protein XP_002347633 [Homo
sapiens]
Length = 261
Score = 35.0 bits (79), Expect = 0.10
Identities = 34/107 (31%), Positives = 45/107 (42%), Gaps = 14/107 (13%)
Query: 27 LSGRPGGSETSARRCLSALSDGLGALRPRAPAARGGVSRASPLLLLLLVPSPRLAAAAPR 86
L GRPG + R LSA G RPR R PL L+L++ P L P
Sbjct: 137 LHGRPG-RDARPWRLLSACPSG----RPRP--------RPLPLPLMLMLMLPTLQPLPPP 183
Query: 87 RQLGDWERSRLGYA-APPAGRSSAWRCSPGVAAAAGALPQYHGPAPA 132
R R G A PA + + R PG ++ + A + P+PA
Sbjct: 184 GSARRPRRGRAGRGGAAPAPPTGSMRAGPGPSSPSAAPTSHPPPSPA 230
>gi|239749325 PREDICTED: hypothetical protein [Homo sapiens]
Length = 155
Score = 35.0 bits (79), Expect = 0.10
Identities = 39/128 (30%), Positives = 53/128 (41%), Gaps = 7/128 (5%)
Query: 4 GSVGGQRTQRLPGRQRLLFLPVGLSGRPGGSETSARRCLSALSDGLGALRPRAPAARGGV 63
G+VG R Q PG + LP L +P G+ + A+ G P G
Sbjct: 30 GTVG--RQQGGPGHGNVDHLP-NLGRQPRGAGSRGASAPRAVRTGAA---PEVVVQSGHR 83
Query: 64 SRASPLLLLLLVPSPRLAAAAPRRQLGDWERSRLGYAAPPAGRSSAWRCSPGVAAAAGAL 123
S AS L +P + RR+ G E SR G AA P GR+ + + G A+ A
Sbjct: 84 SHASKRRFLEEGEAPA-RRLSERRRGGGKEESRPGTAAAPGGRAGLYPRAAGPASREPAR 142
Query: 124 PQYHGPAP 131
P + AP
Sbjct: 143 PTHRPRAP 150
>gi|239745372 PREDICTED: hypothetical protein XP_002343483 [Homo
sapiens]
Length = 261
Score = 35.0 bits (79), Expect = 0.10
Identities = 34/107 (31%), Positives = 45/107 (42%), Gaps = 14/107 (13%)
Query: 27 LSGRPGGSETSARRCLSALSDGLGALRPRAPAARGGVSRASPLLLLLLVPSPRLAAAAPR 86
L GRPG + R LSA G RPR R PL L+L++ P L P
Sbjct: 137 LHGRPG-RDARPWRLLSACPSG----RPRP--------RPLPLPLMLMLMLPTLQPLPPP 183
Query: 87 RQLGDWERSRLGYA-APPAGRSSAWRCSPGVAAAAGALPQYHGPAPA 132
R R G A PA + + R PG ++ + A + P+PA
Sbjct: 184 GSARRPRRGRAGRGGAAPAPPTGSMRAGPGPSSPSAAPTSHPPPSPA 230
>gi|239741653 PREDICTED: hypothetical protein XP_002342271 [Homo
sapiens]
Length = 636
Score = 35.0 bits (79), Expect = 0.10
Identities = 28/83 (33%), Positives = 33/83 (39%), Gaps = 4/83 (4%)
Query: 57 PAARGGVSRASPLLLLLLVPSPRL---AAAAPRRQLGDWERSRLGYAAPPAGRSSAWRCS 113
P R G + P L PSPRL PRR+ G R G P A ++A +
Sbjct: 284 PPTRPGAADICPSRLFA-PPSPRLFPRPGFLPRRRRGVLAHRRRGVLLPAAAAAAAAAAA 342
Query: 114 PGVAAAAGALPQYHGPAPALVSC 136
AAAA L Q P A C
Sbjct: 343 AAAAAAAFCLTQLFAPPTAAAFC 365
>gi|239509122 PREDICTED: hypothetical protein [Homo sapiens]
Length = 155
Score = 35.0 bits (79), Expect = 0.10
Identities = 39/128 (30%), Positives = 53/128 (41%), Gaps = 7/128 (5%)
Query: 4 GSVGGQRTQRLPGRQRLLFLPVGLSGRPGGSETSARRCLSALSDGLGALRPRAPAARGGV 63
G+VG R Q PG + LP L +P G+ + A+ G P G
Sbjct: 30 GTVG--RQQGGPGHGNVDHLP-NLGRQPRGAGSRGASAPRAVRTGAA---PEVVVQSGHR 83
Query: 64 SRASPLLLLLLVPSPRLAAAAPRRQLGDWERSRLGYAAPPAGRSSAWRCSPGVAAAAGAL 123
S AS L +P + RR+ G E SR G AA P GR+ + + G A+ A
Sbjct: 84 SHASKRRFLEEGEAPA-RRLSERRRGGGKEESRPGTAAAPGGRAGLYPRAAGPASREPAR 142
Query: 124 PQYHGPAP 131
P + AP
Sbjct: 143 PTHRPRAP 150
>gi|4506967 v-ski sarcoma viral oncogene homolog [Homo sapiens]
Length = 728
Score = 34.7 bits (78), Expect = 0.14
Identities = 29/116 (25%), Positives = 52/116 (44%), Gaps = 14/116 (12%)
Query: 211 MQQEITFQQV-----MSQIANVKKDMIILEKSEFSALRAENEKIKLELHQLKQQVMDEVI 265
+ QE+ F +V + + K+++ + E LRAENEK E ++ + ++ E+
Sbjct: 587 LHQELEFLRVAKKEKLREATEAKRNL----RKEIERLRAENEKKMKEANESRLRLKRELE 642
Query: 266 KVRTDTKLDFNLEKSRVKELYSLNEKKLLELRTEIVALHAQQDRALTQTDRKIETE 321
+ R D E R++ YS + L ++ HA+ DR + D E E
Sbjct: 643 QARQARVCDKGCEAGRLRAKYSAQIEDL-----QVKLQHAEADREQLRADLLRERE 693
>gi|239747109 PREDICTED: hypothetical protein XP_002344496 [Homo
sapiens]
Length = 146
Score = 34.7 bits (78), Expect = 0.14
Identities = 25/115 (21%), Positives = 62/115 (53%), Gaps = 4/115 (3%)
Query: 193 VKILEANMDIVYKDMVTKMQQEITFQQ-VMSQIANVKKDMIILEKSEFSALRAENEKIKL 251
+K + MDI+ K + K + ++ V S+ N+ KD ++++ S + + E KL
Sbjct: 20 LKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECEKL 79
Query: 252 ELHQLKQQVMDEVIKVRTDTKLDFNLEKSRVKELYSLNEKKLLELRTEIVALHAQ 306
E +Q + + +E++ ++T + + +E S+++E S +++ ++ ++ +H Q
Sbjct: 80 EENQ--KMLEEEILNLKTHME-NSMVELSKLQEYKSELDERAMQAVEKLKEIHLQ 131
>gi|126362971 serine/threonine kinase 10 [Homo sapiens]
Length = 968
Score = 34.7 bits (78), Expect = 0.14
Identities = 30/150 (20%), Positives = 69/150 (46%), Gaps = 14/150 (9%)
Query: 194 KILEANMDIVYKDMVTKMQQEITFQQVMSQIANVKKDMIILEKSEFSALRAENE------ 247
K+ + + K +V ++ IT +++S+ ++M L + E LR +
Sbjct: 521 KLYKKTLKRTRKFVVDGVEVSITTSKIISEDEKKDEEMRFLRRQELRELRLLQKEEHRNQ 580
Query: 248 -----KIKLELHQLKQQVMDEVIKVRT--DTKLDFNLEKSRVKELYSLNEKKLLELRTEI 300
K +L+L Q+ ++ E+ + DT+L+ NLE+ + +++ + + + R E
Sbjct: 581 TQLSNKHELQLEQMHKRFEQEINAKKKFFDTELE-NLERQQKQQVEKMEQDHAVRRREEA 639
Query: 301 VALHAQQDRALTQTDRKIETEVAGLKTMLE 330
+ +QDR T+ +++ +K +E
Sbjct: 640 RRIRLEQDRDYTRFQEQLKLMKKEVKNEVE 669
Score = 30.0 bits (66), Expect = 3.3
Identities = 48/203 (23%), Positives = 92/203 (45%), Gaps = 33/203 (16%)
Query: 147 LQLERKRRDFTSS-GSRKLYFDTHALVCLLEDNGFATQQAEIIVSALVKILEANMDIVYK 205
LQLE+ + F ++K +FDT E QQ + V+ +E + + +
Sbjct: 589 LQLEQMHKRFEQEINAKKKFFDT-------ELENLERQQKQ-----QVEKMEQDHAVRRR 636
Query: 206 DMVTK--MQQEITFQQVMSQIANVKKDMIILEKSEFSAL----RAENEKIKLELHQLKQQ 259
+ + ++Q+ + + Q+ +KK++ K+E L R E+ K K+E H K+Q
Sbjct: 637 EEARRIRLEQDRDYTRFQEQLKLMKKEV----KNEVEKLPRQQRKESMKQKMEEHTQKKQ 692
Query: 260 VMDE--VIKVRTDTKLDF------NLEKSRVKELYSLNEKKLLELRTEIVALHAQQDRAL 311
++D V K + D +L N + KE L +K+ L LR AL ++ L
Sbjct: 693 LLDRDFVAKQKEDLELAMKRLTTDNRREICDKERECLMKKQEL-LRDREAALWEMEEHQL 751
Query: 312 TQTDRKIETEVAGLKTMLESHKL 334
+ + ++ ++ + L+ H+L
Sbjct: 752 QERHQLVKQQLKD-QYFLQRHEL 773
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.133 0.379
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,942,355
Number of Sequences: 37866
Number of extensions: 617065
Number of successful extensions: 3158
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 32
Number of HSP's successfully gapped in prelim test: 252
Number of HSP's that attempted gapping in prelim test: 2964
Number of HSP's gapped (non-prelim): 448
length of query: 359
length of database: 18,247,518
effective HSP length: 103
effective length of query: 256
effective length of database: 14,347,320
effective search space: 3672913920
effective search space used: 3672913920
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.