Search of human proteins with 71143123

Search of human proteins with 71143123

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|71143123 U11/U12 snRNP 48K [Homo sapiens]
         (339 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|71143123 U11/U12 snRNP 48K [Homo sapiens]                          689   0.0  
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ...    49   5e-06
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof...    48   1e-05
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof...    48   1e-05
gi|55741709 RNA binding motif protein 25 [Homo sapiens]                48   1e-05
gi|52426743 cisplatin resistance-associated overexpressed protei...    48   1e-05
gi|19923485 cisplatin resistance-associated overexpressed protei...    48   1e-05
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ...    47   2e-05
gi|56676397 ankyrin repeat domain 11 [Homo sapiens]                    47   3e-05
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]            46   4e-05
gi|239747174 PREDICTED: hypothetical protein XP_002343931, parti...    45   7e-05
gi|29568103 U1 small nuclear ribonucleoprotein 70 kDa [Homo sapi...    45   7e-05
gi|169167715 PREDICTED: hypothetical protein [Homo sapiens]            45   9e-05
gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]            45   1e-04
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ...    45   1e-04
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [...    45   1e-04
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]     44   2e-04
gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3 ...    44   3e-04
gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2 ...    44   3e-04
gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1 [...    44   3e-04
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof...    43   4e-04
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof...    43   4e-04
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s...    43   4e-04
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]     43   5e-04
gi|4759098 splicing factor, arginine/serine-rich 10 [Homo sapiens]     42   8e-04
gi|8922297 LUC7-like isoform a [Homo sapiens]                          42   8e-04
gi|42476169 Paf1, RNA polymerase II associated factor, homolog [...    42   8e-04
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]           42   0.001
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]           42   0.001
gi|41393554 LUC7-like isoform b [Homo sapiens]                         42   0.001

>gi|71143123 U11/U12 snRNP 48K [Homo sapiens]
          Length = 339

 Score =  689 bits (1777), Expect = 0.0
 Identities = 339/339 (100%), Positives = 339/339 (100%)

Query: 1   MEGEPPPVEERRRLQEELNEFVESGCRTLEEVTASLGWDLDSLDPGEEEAAEDEVVICPY 60
           MEGEPPPVEERRRLQEELNEFVESGCRTLEEVTASLGWDLDSLDPGEEEAAEDEVVICPY
Sbjct: 1   MEGEPPPVEERRRLQEELNEFVESGCRTLEEVTASLGWDLDSLDPGEEEAAEDEVVICPY 60

Query: 61  DSNHHMPKSSLAKHMASCRLRKMGYTKEEEDEMYNPEFFYENVKIPSITLNKDSQFQIIK 120
           DSNHHMPKSSLAKHMASCRLRKMGYTKEEEDEMYNPEFFYENVKIPSITLNKDSQFQIIK
Sbjct: 61  DSNHHMPKSSLAKHMASCRLRKMGYTKEEEDEMYNPEFFYENVKIPSITLNKDSQFQIIK 120

Query: 121 QARTAVGKDSDCYNQRIYSSLPVEVPLNHKRFVCDLTQADRLALYDFVVEETKKKRSDSQ 180
           QARTAVGKDSDCYNQRIYSSLPVEVPLNHKRFVCDLTQADRLALYDFVVEETKKKRSDSQ
Sbjct: 121 QARTAVGKDSDCYNQRIYSSLPVEVPLNHKRFVCDLTQADRLALYDFVVEETKKKRSDSQ 180

Query: 181 IIENDSDLFVDLAAKINQDNSRKSPKSYLEILAEVRDYKRRRQSYRAKNVHITKKSYTEV 240
           IIENDSDLFVDLAAKINQDNSRKSPKSYLEILAEVRDYKRRRQSYRAKNVHITKKSYTEV
Sbjct: 181 IIENDSDLFVDLAAKINQDNSRKSPKSYLEILAEVRDYKRRRQSYRAKNVHITKKSYTEV 240

Query: 241 IRDVINVHMEELSNHWQEEQEKAEDDAEKNEERRSASVDSRQSGGSYLDAECSRHRRDRS 300
           IRDVINVHMEELSNHWQEEQEKAEDDAEKNEERRSASVDSRQSGGSYLDAECSRHRRDRS
Sbjct: 241 IRDVINVHMEELSNHWQEEQEKAEDDAEKNEERRSASVDSRQSGGSYLDAECSRHRRDRS 300

Query: 301 RSPHKRKRNKDKDKNCESRRRKERDGERHHSHKRRKQKI 339
           RSPHKRKRNKDKDKNCESRRRKERDGERHHSHKRRKQKI
Sbjct: 301 RSPHKRKRNKDKDKNCESRRRKERDGERHHSHKRRKQKI 339


>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
           containing B [Homo sapiens]
          Length = 546

 Score = 49.3 bits (116), Expect = 5e-06
 Identities = 37/148 (25%), Positives = 66/148 (44%), Gaps = 3/148 (2%)

Query: 193 AAKINQDNSRKSPKSYLEILAEVRDYKRRRQSYRAKNVHITKKSYTEVIRDVINVHMEEL 252
           A +I++   R+  +S    L+  R  +R R     +  H +     E+ R+     +E  
Sbjct: 248 AEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLERE 307

Query: 253 SNHWQEEQEKAEDDAEKNEERRSASVDSRQSGGSYLDAECSRHRRDRSRSPHK---RKRN 309
           +   ++E+ ++       E RRS S +  +S     D +  R  RDR R       R+R+
Sbjct: 308 AKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRD 367

Query: 310 KDKDKNCESRRRKERDGERHHSHKRRKQ 337
           +D DK   + R KER+  R  S ++R +
Sbjct: 368 RDYDKERGNEREKERERSRERSKEQRSR 395



 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 41/169 (24%), Positives = 74/169 (43%), Gaps = 13/169 (7%)

Query: 170 EETKKKRSDSQIIENDSDLFVDLAAKINQDNSRKSPKSYLEILAEVRDYKRRRQSYRAKN 229
           E +K++RS  ++ E       D   + ++D+ R S K      +  R+ K R +S R++N
Sbjct: 387 ERSKEQRSRGEVEEKKHK--EDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRS-RSRN 443

Query: 230 VHITKKSYTEVIRDVINVHMEELSNHWQEEQEKAEDDAEKNEERRSASVDSRQSGGSYLD 289
                +S ++          E+ S H  E +EK+   +    + R+ SV+  +       
Sbjct: 444 AGKRSRSRSK----------EKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPS 493

Query: 290 AECSRHRRDRSRSPHKRKRNKDKDKNCESRRRKERDGERHHSHKRRKQK 338
            E SR R       HKR  +  KD++ +  RR+ +  E+    K+ K K
Sbjct: 494 KEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQESQEKQHKNK 542



 Score = 35.0 bits (79), Expect = 0.096
 Identities = 24/121 (19%), Positives = 51/121 (42%), Gaps = 6/121 (4%)

Query: 216 RDYKRRRQSYRAKNVHITKKSYTEVIRDVINVHMEELSNHWQEEQEKAEDDAEKNEERRS 275
           RD +R +++ R +      + Y +   +      E      +E++ + E + +K++E + 
Sbjct: 352 RDREREKENERGRR---RDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKD 408

Query: 276 ASVDSRQSGGSYLDAECSRHRRDRSRSPHKRKRNKDKDKNCESRRRKERDGERHHSHKRR 335
              D R         +  +H R RSR    R R++ ++    SR R +    +H +  + 
Sbjct: 409 ---DRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKE 465

Query: 336 K 336
           K
Sbjct: 466 K 466



 Score = 33.9 bits (76), Expect = 0.21
 Identities = 28/128 (21%), Positives = 55/128 (42%), Gaps = 8/128 (6%)

Query: 216 RDYKRRRQSYRAKNVHITKKSYTEVIRDVINVHMEELSNHWQEEQ--EKAEDDAEKNEER 273
           R+ +R+R    AK     ++    + R +          H    +  ++  D  +++ ER
Sbjct: 297 REKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDRER 356

Query: 274 RSASVDSRQSGGSYLDAECSRHR---RDRSRSPHKRKRNKDKDKNCESRRRKERDGERHH 330
              +   R+    Y D E    R   R+RSR   K +R++ + +  E + ++++D  RH 
Sbjct: 357 EKENERGRRRDRDY-DKERGNEREKERERSRERSKEQRSRGEVE--EKKHKEDKDDRRHR 413

Query: 331 SHKRRKQK 338
             KR  +K
Sbjct: 414 DDKRDSKK 421


>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           5 [Homo sapiens]
          Length = 748

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 45/176 (25%), Positives = 70/176 (39%), Gaps = 18/176 (10%)

Query: 166 DFVVEETKKKRSDSQIIENDSDLFVDLAAKINQDNSRKSPKSYLEILAEVRDYKRRRQSY 225
           +  +  +  +R DS     + D    LA K  Q  SRK    + +   E R  KRR +S+
Sbjct: 25  EITIRNSPYRREDSMEDRGEED--DSLAIKPPQQMSRKEKVHHRK--DEKRKEKRRHRSH 80

Query: 226 RA---KNVHITKKSYTEVIRDVINVHMEELSNHWQEEQEKAEDDAEKNEERRSASVDSRQ 282
            A   K+  + +K               E     +EEQ+KA  + E+ + R  A   SR+
Sbjct: 81  SAEGGKHARVKEKE-----------REHERRKRHREEQDKARREWERQKRREMAREHSRR 129

Query: 283 SGGSYLDAECSRHRRDRSRSPHKRKRNKDKDKNCESRRRKERDGERHHSHKRRKQK 338
                   E  R R  + R   K +R + + +     RRKER+  R  S   R  +
Sbjct: 130 ERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMR 185



 Score = 31.6 bits (70), Expect = 1.1
 Identities = 20/70 (28%), Positives = 31/70 (44%), Gaps = 1/70 (1%)

Query: 257 QEEQEKAEDDAEKNEERRSASVDSRQSGGSYLD-AECSRHRRDRSRSPHKRKRNKDKDKN 315
           +E + +AE+  ++ E RR  S   R     Y D  + S   R   R P +R    D  K 
Sbjct: 158 KERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKP 217

Query: 316 CESRRRKERD 325
            +  + +ERD
Sbjct: 218 VKEEKMEERD 227


>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           2 [Homo sapiens]
          Length = 782

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 45/176 (25%), Positives = 70/176 (39%), Gaps = 18/176 (10%)

Query: 166 DFVVEETKKKRSDSQIIENDSDLFVDLAAKINQDNSRKSPKSYLEILAEVRDYKRRRQSY 225
           +  +  +  +R DS     + D    LA K  Q  SRK    + +   E R  KRR +S+
Sbjct: 59  EITIRNSPYRREDSMEDRGEED--DSLAIKPPQQMSRKEKVHHRK--DEKRKEKRRHRSH 114

Query: 226 RA---KNVHITKKSYTEVIRDVINVHMEELSNHWQEEQEKAEDDAEKNEERRSASVDSRQ 282
            A   K+  + +K               E     +EEQ+KA  + E+ + R  A   SR+
Sbjct: 115 SAEGGKHARVKEKE-----------REHERRKRHREEQDKARREWERQKRREMAREHSRR 163

Query: 283 SGGSYLDAECSRHRRDRSRSPHKRKRNKDKDKNCESRRRKERDGERHHSHKRRKQK 338
                   E  R R  + R   K +R + + +     RRKER+  R  S   R  +
Sbjct: 164 ERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMR 219



 Score = 31.6 bits (70), Expect = 1.1
 Identities = 20/70 (28%), Positives = 31/70 (44%), Gaps = 1/70 (1%)

Query: 257 QEEQEKAEDDAEKNEERRSASVDSRQSGGSYLD-AECSRHRRDRSRSPHKRKRNKDKDKN 315
           +E + +AE+  ++ E RR  S   R     Y D  + S   R   R P +R    D  K 
Sbjct: 192 KERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKP 251

Query: 316 CESRRRKERD 325
            +  + +ERD
Sbjct: 252 VKEEKMEERD 261



 Score = 31.2 bits (69), Expect = 1.4
 Identities = 28/104 (26%), Positives = 45/104 (43%), Gaps = 22/104 (21%)

Query: 257 QEEQEKAEDDAEKNEERRSASVDSRQSG-----GSYLDAECSRHRRDRSR---------- 301
           +E++EKAE    KN + R +  DS + G        +    S +RR+ S           
Sbjct: 24  KEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRGEEDDSL 83

Query: 302 --SPHKRKRNKDKDKNCESRRRKERDGERHHS-----HKRRKQK 338
              P ++   K+K  + +  +RKE+   R HS     H R K+K
Sbjct: 84  AIKPPQQMSRKEKVHHRKDEKRKEKRRHRSHSAEGGKHARVKEK 127



 Score = 30.0 bits (66), Expect = 3.1
 Identities = 31/150 (20%), Positives = 65/150 (43%), Gaps = 20/150 (13%)

Query: 206 KSYLEILAEVRDYKRRRQSYRAKNVHITKKSYTEVIRDVINVHMEELSNHWQE------- 258
           K+  EIL E +  +R+ Q  +A+   +      +  RD  ++   EL +H  E       
Sbjct: 11  KTLDEILQEKK--RRKEQEEKAEIKRLKNSDDRDSKRD--SLEEGELRDHRMEITIRNSP 66

Query: 259 --EQEKAEDDAEKNEE---RRSASVDSRQSGGSYLDAECSRHRRDRSRSP----HKRKRN 309
              ++  ED  E+++    +    +  ++      D +    RR RS S     H R + 
Sbjct: 67  YRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKRRHRSHSAEGGKHARVKE 126

Query: 310 KDKDKNCESRRRKERDGERHHSHKRRKQKI 339
           K+++     R R+E+D  R    +++++++
Sbjct: 127 KEREHERRKRHREEQDKARREWERQKRREM 156



 Score = 28.9 bits (63), Expect = 6.9
 Identities = 36/182 (19%), Positives = 77/182 (42%), Gaps = 25/182 (13%)

Query: 166 DFVVEETKKKRSDSQIIENDSDLFVDLAAKINQDNSRKSPKSYLEILAEVRDYKR----R 221
           D +++E K+++   +  E           ++   + R S +  LE   E+RD++     R
Sbjct: 14  DEILQEKKRRKEQEEKAE---------IKRLKNSDDRDSKRDSLEE-GELRDHRMEITIR 63

Query: 222 RQSYRAKNVHITKKSYTE--VIRDVINVHMEELSNHWQEEQEKAEDDAEKNEERRSASVD 279
              YR ++    +    +   I+    +  +E  +H ++E+ K     EK   R  ++  
Sbjct: 64  NSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRK-----EKRRHRSHSAEG 118

Query: 280 SRQSGGSYLDAECSR---HRRDRSRSPHKRKRNKDKDKNCESRRRKERDGERHHSHKRRK 336
            + +     + E  R   HR ++ ++  + +R K ++   E  RR ERD       KR +
Sbjct: 119 GKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRR-ERDRLEQLERKRER 177

Query: 337 QK 338
           ++
Sbjct: 178 ER 179


>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
          Length = 843

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 40/171 (23%), Positives = 74/171 (43%), Gaps = 11/171 (6%)

Query: 169 VEETKKKRSDSQIIENDSDLFVDLAAKINQDNSRKSPKSYLEILAEVRDYKRRRQSYRAK 228
           +EE K+      +I  +   F D   K+ ++  +K  K   EI  E R+ +R R+  R +
Sbjct: 269 MEEDKR-----DLISREISKFRDTHKKLEEEKGKKE-KERQEIEKERRERERERERERER 322

Query: 229 NVHITKKSYTEVIRDVINVHMEELSNHWQEEQEKAEDDAEKNEERRSASVDSRQSGGSYL 288
                ++   E  R+       E       ++++ ++     +  R    D  +S     
Sbjct: 323 R---EREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNK 379

Query: 289 DAECSRHR-RDRSRSPHKRKRNKDKDKNCESRRRKERDGERHHSHKRRKQK 338
           D   SR + RDR R   +R+R +++++  E  R +ER+ ER    +R K K
Sbjct: 380 DRSRSREKSRDRERE-REREREREREREREREREREREREREREREREKDK 429



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 40/164 (24%), Positives = 69/164 (42%), Gaps = 20/164 (12%)

Query: 174 KKRSDSQIIENDSDLFVDLAAKINQDNSRKSPKSYLEILAEVRDYKRRRQSYRAKNVHIT 233
           K+R   +  E D D   + ++  N+D SR   KS        RD +R R+  R +     
Sbjct: 355 KERDRDRDRERDRDRDRERSSDRNKDRSRSREKS--------RDRERERERERERERERE 406

Query: 234 KKSYTEVIRDVINVHMEELSNHWQEEQEKAEDDAEKNEERRSASVDSRQSGGSYLDAECS 293
           ++   E  R+       E     + ++E+ E+DA    ERR      R+   +Y      
Sbjct: 407 REREREREREREREREREREKDKKRDREEDEEDAY---ERRKLERKLREKEAAY------ 457

Query: 294 RHRRDRSRSPHKRKRNKDKDKNCESRRRKERDGERHHSHKRRKQ 337
              ++R ++   R+R K ++   E+ R +ER  E     KR K+
Sbjct: 458 ---QERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKE 498



 Score = 28.5 bits (62), Expect = 9.0
 Identities = 28/130 (21%), Positives = 51/130 (39%), Gaps = 19/130 (14%)

Query: 216 RDYKRRRQSYRAKNVHITKKSYTEVIRDVINVHMEELSNHWQEEQEKA---EDDAEKNEE 272
           R+  ++R     +     ++     +R+    + E L N    E++K    E +AE+ EE
Sbjct: 425 REKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEE 484

Query: 273 RRSASV--------------DSRQSGGSYLDAECSRHRRDRSR--SPHKRKRNKDKDKNC 316
           RR                  D R     Y  +   +  RDR +     +R R ++K++  
Sbjct: 485 RRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELE 544

Query: 317 ESRRRKERDG 326
           E R+R   +G
Sbjct: 545 EIRQRLLAEG 554


>gi|52426743 cisplatin resistance-associated overexpressed protein
           [Homo sapiens]
          Length = 432

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 39/160 (24%), Positives = 67/160 (41%), Gaps = 12/160 (7%)

Query: 191 DLAAKINQDNSRKSPKSYLEILAEVRDYK---RRRQSYRAKNVHITKKSYTEVIRDVINV 247
           D  ++++     K    Y +I A V + K   R+R     ++  + K+      R+    
Sbjct: 203 DAQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKERE 262

Query: 248 H-MEELSNHWQEEQEKAEDDAEKNEERRSASVDSRQSGGSYLDAECSR---HRRDRSRSP 303
              EE     + E+E+ E +  ++ ERR  S    +      D  CSR   H+R RSR  
Sbjct: 263 REREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRER 322

Query: 304 HK-----RKRNKDKDKNCESRRRKERDGERHHSHKRRKQK 338
            +     R+R++  D++    R + RD  R  S  R+  K
Sbjct: 323 RRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYK 362



 Score = 36.6 bits (83), Expect = 0.033
 Identities = 40/170 (23%), Positives = 72/170 (42%), Gaps = 33/170 (19%)

Query: 170 EETKKKRSDSQIIENDSDLFVDLAAKINQDNSRKSPKSYLEILAE-VRDYKRRRQSYRAK 228
           E  KK++ + +  E + +       +  ++  RK  +   E   E  RD +RR++S R++
Sbjct: 245 ERLKKEKQEREEREKERE-------REREERERKRRREEEEREKERARDRERRKRS-RSR 296

Query: 229 NVHITKKSYTEVIRDVINVHMEELSNHWQEEQEKAEDDAEKNEERRSASVDSRQSGGSYL 288
           + H ++ S     R                   +    +   E RRS S D R+S     
Sbjct: 297 SRHSSRTSDRRCSR------------------SRDHKRSRSRERRRSRSRDRRRS----- 333

Query: 289 DAECSRHRRDRSRSPHKRKRNKDKDKNCESRRRKERDGERHHSHKRRKQK 338
            +     R+ RSRS   R+R+K +D+     R K RD E+    K ++++
Sbjct: 334 RSHDRSERKHRSRS-RDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKR 382


>gi|19923485 cisplatin resistance-associated overexpressed protein
           [Homo sapiens]
          Length = 432

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 39/160 (24%), Positives = 67/160 (41%), Gaps = 12/160 (7%)

Query: 191 DLAAKINQDNSRKSPKSYLEILAEVRDYK---RRRQSYRAKNVHITKKSYTEVIRDVINV 247
           D  ++++     K    Y +I A V + K   R+R     ++  + K+      R+    
Sbjct: 203 DAQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKERE 262

Query: 248 H-MEELSNHWQEEQEKAEDDAEKNEERRSASVDSRQSGGSYLDAECSR---HRRDRSRSP 303
              EE     + E+E+ E +  ++ ERR  S    +      D  CSR   H+R RSR  
Sbjct: 263 REREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRER 322

Query: 304 HK-----RKRNKDKDKNCESRRRKERDGERHHSHKRRKQK 338
            +     R+R++  D++    R + RD  R  S  R+  K
Sbjct: 323 RRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYK 362



 Score = 36.6 bits (83), Expect = 0.033
 Identities = 40/170 (23%), Positives = 72/170 (42%), Gaps = 33/170 (19%)

Query: 170 EETKKKRSDSQIIENDSDLFVDLAAKINQDNSRKSPKSYLEILAE-VRDYKRRRQSYRAK 228
           E  KK++ + +  E + +       +  ++  RK  +   E   E  RD +RR++S R++
Sbjct: 245 ERLKKEKQEREEREKERE-------REREERERKRRREEEEREKERARDRERRKRS-RSR 296

Query: 229 NVHITKKSYTEVIRDVINVHMEELSNHWQEEQEKAEDDAEKNEERRSASVDSRQSGGSYL 288
           + H ++ S     R                   +    +   E RRS S D R+S     
Sbjct: 297 SRHSSRTSDRRCSR------------------SRDHKRSRSRERRRSRSRDRRRS----- 333

Query: 289 DAECSRHRRDRSRSPHKRKRNKDKDKNCESRRRKERDGERHHSHKRRKQK 338
            +     R+ RSRS   R+R+K +D+     R K RD E+    K ++++
Sbjct: 334 RSHDRSERKHRSRS-RDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKR 382


>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
           sapiens]
          Length = 600

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 43/171 (25%), Positives = 73/171 (42%), Gaps = 4/171 (2%)

Query: 171 ETKKKRSDSQIIENDSDLFVDLAAKINQDNSRKSPKSYLEILAEVRDYKRRRQSYRAKNV 230
           E + +R   +  E D D   D   K  +  + +  +   E   E  + KR RQ  R +  
Sbjct: 253 ERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRET-ERKRERQRERERER 311

Query: 231 HITKKSYTEVIRDVINVHMEELSNHWQEEQE-KAEDDAEKNEER-RSASVDSRQSGGSYL 288
              +K   E  R+       E     ++E+E K +   E + ER R    + R+      
Sbjct: 312 ERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERER 371

Query: 289 DAECSRHRRD-RSRSPHKRKRNKDKDKNCESRRRKERDGERHHSHKRRKQK 338
           + E  R R+  R R   +R R++D+ K  E +  K+RDG+R    +R ++K
Sbjct: 372 ERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREK 422



 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 29/139 (20%), Positives = 65/139 (46%), Gaps = 2/139 (1%)

Query: 200 NSRKSPKSYLEILAEVRDYKRRRQSYRAKNVHITKKSYTEVIRDVINVHMEELSNHWQEE 259
           N +K  +   E     R+  R+R+  R K+ H  +  + E  RD      E  ++  ++ 
Sbjct: 57  NRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDR-EKERERQTDRERDR 115

Query: 260 QEKAEDDAEKNEERRSASVDSRQSGGSYLDAECSRHRRDRSRSPHKRKRNKDKDKNCESR 319
           Q + E + +K  ER +   +  +      D +  R R+  +    +R+ ++++ +  E  
Sbjct: 116 QREKERNRQKERERETER-EGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERN 174

Query: 320 RRKERDGERHHSHKRRKQK 338
           R+KER+ E++   +R +++
Sbjct: 175 RQKEREREKNRQERRERER 193



 Score = 45.1 bits (105), Expect = 9e-05
 Identities = 31/129 (24%), Positives = 57/129 (44%), Gaps = 19/129 (14%)

Query: 216 RDYKRRRQSYRAKNVHITKKSYTEVIRDVINVHMEELSNHWQEEQEKAED-DAEKNEERR 274
           RD +R+ +  R K     + S  E  RD             + E+E+  D D ++ ++ R
Sbjct: 232 RDRQRKTEREREKQAERERASERETERDK------------ERERERDRDRDRDRRQKER 279

Query: 275 SASVDSRQSGGSYLDAECSRHRRDRSRSPHKRKRN------KDKDKNCESRRRKERDGER 328
               D ++   +  D E  R R  +     +R+RN      +++++  E +R  ERD E+
Sbjct: 280 ERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREK 339

Query: 329 HHSHKRRKQ 337
               KR++Q
Sbjct: 340 ERERKRKRQ 348



 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 35/174 (20%), Positives = 73/174 (41%), Gaps = 8/174 (4%)

Query: 171 ETKKKRSDSQIIENDSDLFVDLAAKINQDNSRKSPKSYLEILAEVRDYKRR-----RQSY 225
           E +++R   +  E  +D       + N+   R+  K+  E     R  ++      R S 
Sbjct: 148 ERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSE 207

Query: 226 RAKNVHITKKSYTEVIRDVINVHMEELSNHWQEEQEKAEDDAEKNEERRSASVDSRQSGG 285
           R +     +++ TE  R        +     + E+EK  +    +E  R    D  +   
Sbjct: 208 RGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASE--RETERDKERERE 265

Query: 286 SYLDAECSRHRRDRSR-SPHKRKRNKDKDKNCESRRRKERDGERHHSHKRRKQK 338
              D +  R +++R R +  KR+R  ++D+  E +R ++R+ ER     R++++
Sbjct: 266 RDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRER 319



 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 34/124 (27%), Positives = 58/124 (46%), Gaps = 5/124 (4%)

Query: 216 RDYKRRRQSYRAKNVHITKKSYTEVIRDVINVHMEELSNHWQEEQEKAEDDAEKNEERRS 275
           R   R R   R K  +  K+   E  R+       +     Q E+E+ + DAEK  ER++
Sbjct: 107 RQTDRERDRQREKERNRQKERERETERE--GERGRDRQTDGQRERER-QRDAEKERERQT 163

Query: 276 ASVDSRQS-GGSYLDAECSRHRRD-RSRSPHKRKRNKDKDKNCESRRRKERDGERHHSHK 333
                RQ+      + E  ++R++ R R   + K NK +D++ E  R +ER+ E     +
Sbjct: 164 DRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETE 223

Query: 334 RRKQ 337
           R++Q
Sbjct: 224 RKRQ 227



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 25/123 (20%), Positives = 53/123 (43%), Gaps = 1/123 (0%)

Query: 216 RDYKRRRQSYRAKNVHITKKSYTEVIRDVINVHMEELSNHWQEEQEKAEDDAEKNEERRS 275
           R+ +R+R + + +     ++   +  R+       E +   + E+E+  +   K E+R S
Sbjct: 147 RERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHS 206

Query: 276 ASVDSRQSGGSYLDAECSRHRRDRSRSPHKRKRNKDKDKNCESRRRKERDGERHHSHKRR 335
                R+      + E  R R+       +RK  ++++K  E  R  ER+ ER    +R 
Sbjct: 207 ERGRERERERE-TETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERE 265

Query: 336 KQK 338
           + +
Sbjct: 266 RDR 268



 Score = 38.5 bits (88), Expect = 0.009
 Identities = 23/85 (27%), Positives = 41/85 (48%), Gaps = 4/85 (4%)

Query: 257 QEEQEKAEDDAEKNEERRSASVDSRQSGGSYLDAECSRHR---RDRSRSPHKRKRNKDKD 313
           Q  ++   DD E+N ++       ++      D +  R R   R R R  H R+R +D++
Sbjct: 44  QAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRH-RERQRDRE 102

Query: 314 KNCESRRRKERDGERHHSHKRRKQK 338
           K  E +  +ERD +R     R+K++
Sbjct: 103 KERERQTDRERDRQREKERNRQKER 127



 Score = 38.5 bits (88), Expect = 0.009
 Identities = 31/171 (18%), Positives = 72/171 (42%), Gaps = 5/171 (2%)

Query: 171 ETKKKRSDSQIIENDSDLFVDLAAKINQDNSRKSPKSYLEILAEVRDYKRRRQSY--RAK 228
           ET++KR   +  E + +       +  ++  R+  +       + R+ KR+RQ+   R +
Sbjct: 296 ETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRER 355

Query: 229 NVHITKKSYTEVIRDVINVHMEELSNHWQEEQEKAEDDAEKNEERRSASVDSRQSGGSYL 288
           N    ++   +  R+       +  +  + E+ + + D ++ +ER   +   R       
Sbjct: 356 NRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDG---QR 412

Query: 289 DAECSRHRRDRSRSPHKRKRNKDKDKNCESRRRKERDGERHHSHKRRKQKI 339
           + E  R R     S   R+R ++++K     R +ER  +R    +R++  +
Sbjct: 413 ETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTL 463



 Score = 35.4 bits (80), Expect = 0.073
 Identities = 16/69 (23%), Positives = 35/69 (50%), Gaps = 3/69 (4%)

Query: 273 RRSASVDS---RQSGGSYLDAECSRHRRDRSRSPHKRKRNKDKDKNCESRRRKERDGERH 329
           RR  S +S   R  G ++ DA+     R+R +   +R+  +  ++  + +R + R+ +RH
Sbjct: 29  RRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRH 88

Query: 330 HSHKRRKQK 338
               R +++
Sbjct: 89  RKRDRHRER 97


>gi|56676397 ankyrin repeat domain 11 [Homo sapiens]
          Length = 2663

 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 54/197 (27%), Positives = 86/197 (43%), Gaps = 39/197 (19%)

Query: 170  EETKKKRSDSQIIENDSDLFVDLAAKINQDNSRKSP-------------KSYLEILAEVR 216
            E+TK   SD Q     SDL  D +     ++S  SP             K  LE + E  
Sbjct: 827  EDTKFSLSDDQRDRWFSDLS-DSSFDFKGEDSWDSPVTDYRDMKSDSVAKLILETVKE-- 883

Query: 217  DYKRRRQSYRAKNVHITKKSYTEVI-----RDVINVHMEELSNHWQEEQEKAEDDAEKNE 271
            D K RR+  RA+     K+ Y E       RD ++ + E+     ++ +      +EK++
Sbjct: 884  DSKERRRDSRARE----KRDYREPFFRKKDRDYLDKNSEKRKEQTEKHKSVPGYLSEKDK 939

Query: 272  ERRSASVDSRQSGGSYLDA-ECSRHRRDRSRSPHKRKRNKDKDKNCESRRRKERDG---- 326
            +RR    +S ++G    DA E  + RRD    P +  R + K+  CES  + + DG    
Sbjct: 940  KRR----ESAEAGRDRKDALESCKERRDGRAKPEEAHREELKECGCESGFKDKSDGDFGK 995

Query: 327  -----ERHHSHKRRKQK 338
                 ERHH  + +++K
Sbjct: 996  GLEPWERHHPAREKEKK 1012



 Score = 33.9 bits (76), Expect = 0.21
 Identities = 23/87 (26%), Positives = 44/87 (50%), Gaps = 9/87 (10%)

Query: 253  SNHWQEEQEKAEDDAEKNEERRSASVDSRQSGGSYLDAECSRHRRDRSRSPHKRKRNKDK 312
            S+  ++  +K   + +K++E R    D R+  G+   A+  R ++++    HK K  KDK
Sbjct: 1161 SDRHRKSSDKQHPERQKDKEPR----DRRKDRGA---ADAGRDKKEKVFEKHKEK--KDK 1211

Query: 313  DKNCESRRRKERDGERHHSHKRRKQKI 339
            +   + + RK+R        K+ KQK+
Sbjct: 1212 ESTEKYKDRKDRASVDSTQDKKNKQKL 1238



 Score = 33.1 bits (74), Expect = 0.36
 Identities = 35/165 (21%), Positives = 66/165 (40%), Gaps = 15/165 (9%)

Query: 182  IENDSDLFVDLAAKINQDNSRKSPKSYLEILAEVRDY----------KRRRQSYRAKNVH 231
            IE++ D  ++L +   +D +    +   +I  E++ Y          K++R+ +R K   
Sbjct: 1412 IEDELDKTIELFSTEKKDKNDSEREPSKKIEKELKPYGSSAINILKEKKKREKHREKWRD 1471

Query: 232  ITKKSYTEVIRDVINVHMEELSNHWQEEQEKAEDDAEKNEERRSASVDSRQSGGSYLDAE 291
              ++        ++  H +EL  H ++EQ+ A  D  K+   R     SR  G    DA+
Sbjct: 1472 EKERHRDRHADGLLRHHRDELLRHHRDEQKPATRD--KDSPPRVLKDKSRDEGPRLGDAK 1529

Query: 292  CSRHRRDRSRSPHKRKRNKDKDKNCESRRRKERDGERHHSHKRRK 336
                 +D      K K +  K  N   +    +D  +  +  R K
Sbjct: 1530 LKEKFKD---GAEKEKGDPVKMSNGNDKVAPSKDPGKKDARPREK 1571



 Score = 32.0 bits (71), Expect = 0.81
 Identities = 37/198 (18%), Positives = 84/198 (42%), Gaps = 41/198 (20%)

Query: 148 NHKRFVCDLTQADRLALYDFVVEETKKKRSDSQIIENDSDLFVDLAAKINQDNSRKSPKS 207
           N ++  C ++Q  +L  + +  E++K+K   + ++END                  S ++
Sbjct: 640 NKEKGQCSISQELKLKSFTYEYEDSKQKSDKAILLEND-----------------LSTEN 682

Query: 208 YLEILAEVRDYKRRRQSYRAKNVHITKKSY---TEVIRDVINVHMEELSNHWQEEQEKAE 264
            L++L   RD+ ++ +  +   + + +K +    E     I    +++S  ++EE    +
Sbjct: 683 KLKVLKHDRDHFKKEE--KLSKMKLEEKEWLFKDEKSLKRIKDTNKDISRSFREE----K 736

Query: 265 DDAEKNEERRSASVDSRQSGGSYLDAECSRHRRDRSRSPHKRKRNKDKDKNCESRRRKER 324
           D + K E+ RS            L  +  +  + R     ++K++KD+    E +   + 
Sbjct: 737 DRSNKAEKERS------------LKEKSPKEEKLRLYKEERKKKSKDRPSKLEKKNDLKE 784

Query: 325 D---GERHHSHKRRKQKI 339
           D    E+    K  K+K+
Sbjct: 785 DKISKEKEKIFKEDKEKL 802



 Score = 32.0 bits (71), Expect = 0.81
 Identities = 23/88 (26%), Positives = 44/88 (50%), Gaps = 7/88 (7%)

Query: 257  QEEQEKAEDDAEKNEERRS-ASVDSRQSGGSYLD----AECSRHRRDRSRSPHKRKRNKD 311
            + +++K ++  EK ++R+  ASVDS Q   +       AE      D+++S HK K   D
Sbjct: 1204 KHKEKKDKESTEKYKDRKDRASVDSTQDKKNKQKLPEKAEKKHAAEDKAKSKHKEK--SD 1261

Query: 312  KDKNCESRRRKERDGERHHSHKRRKQKI 339
            K+ + E +  +  D E+    K  ++ +
Sbjct: 1262 KEHSKERKSSRSADAEKSLLEKLEEEAL 1289



 Score = 30.4 bits (67), Expect = 2.4
 Identities = 32/172 (18%), Positives = 68/172 (39%), Gaps = 11/172 (6%)

Query: 170  EETKKKRSDSQIIENDSDLFVDLAAKINQDNSRKSPKSYLEILAEVRDYKRRRQSYRAKN 229
            ++TK+K  D+   + +    +D           K  K++  I++E    K+  +  + K+
Sbjct: 1060 KDTKEKHKDTHGKDKERKASLD-------QGKEKKEKAFPGIISEDFSEKKDDKKGKEKS 1112

Query: 230  VHITKKSYTEVIRDVINVHMEELSNHWQEEQEKAEDDAEKNEERRSASVDSRQSGGS--- 286
             +I    +T+   D  +  M       +       D  ++ EE R A    R    S   
Sbjct: 1113 WYIAD-IFTDESEDDRDSCMGSGFKMGEASDLPRTDGLQEKEEGREAYASDRHRKSSDKQ 1171

Query: 287  YLDAECSRHRRDRSRSPHKRKRNKDKDKNCESRRRKERDGERHHSHKRRKQK 338
            + + +  +  RDR +        +DK +    + ++++D E    +K RK +
Sbjct: 1172 HPERQKDKEPRDRRKDRGAADAGRDKKEKVFEKHKEKKDKESTEKYKDRKDR 1223


>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 245

 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 26/90 (28%), Positives = 48/90 (53%), Gaps = 5/90 (5%)

Query: 250 EELSNHWQEEQEKAEDDAEKNEERRSASVDSRQSGGSYLDAECSRHRRDRSRSPHKRKRN 309
           EE     ++E+E+ +++ EK  ER+      R+  G   +    + R++R     KR+RN
Sbjct: 137 EERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERK----KRERN 192

Query: 310 -KDKDKNCESRRRKERDGERHHSHKRRKQK 338
            K++ K  E + R+ER  ER    +R+K++
Sbjct: 193 RKERKKERERKERRERKKERKKKEERKKER 222



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 21/65 (32%), Positives = 38/65 (58%), Gaps = 5/65 (7%)

Query: 274 RSASVDSRQSGGSYLDAECSRHRRDRSRSPHKRKRNKDKDKNCESRRRKERDGERHHSHK 333
           R   +++R+ G    ++E  + RR+R     KRKR ++K++  E R +KE+ GER    +
Sbjct: 41  REREIETRKEGKKERESERKKERRER----EKRKREREKERKRE-RGKKEKKGERKKEER 95

Query: 334 RRKQK 338
            RK++
Sbjct: 96  ERKKR 100



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 36/169 (21%), Positives = 73/169 (43%), Gaps = 13/169 (7%)

Query: 179 SQIIENDSDLFVDLAAKINQDNSRKSPKSYLEILAEVRDYKRRRQSYRAKNVHITKKSYT 238
           S+I E + ++      K  +++ RK  +   E     R+ +R+R+  + +     KK   
Sbjct: 36  SEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEER 95

Query: 239 EVI---RDVINVHMEELSNHWQEEQE------KAEDDAEKNEERRSASVDSRQSGGSYLD 289
           E     R+  N   EE     ++E++      K   + E+ EER+      R+       
Sbjct: 96  ERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKE--- 152

Query: 290 AECSRHRRDRSRSPHKRKRNKDKDKNCESRRRKERDGERHHSHKRRKQK 338
            E  + R  + R   +RK+  +K++  + + RKER     +  +R+K++
Sbjct: 153 -EREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKER 200



 Score = 33.5 bits (75), Expect = 0.28
 Identities = 25/139 (17%), Positives = 52/139 (37%)

Query: 195 KINQDNSRKSPKSYLEILAEVRDYKRRRQSYRAKNVHITKKSYTEVIRDVINVHMEELSN 254
           K  ++  ++  K   E     ++ K R +    K     ++   +  R+      E    
Sbjct: 107 KEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKR 166

Query: 255 HWQEEQEKAEDDAEKNEERRSASVDSRQSGGSYLDAECSRHRRDRSRSPHKRKRNKDKDK 314
             ++  EK E+  EK  + R     +R+      + +  R R+   +   +RK+ + KD+
Sbjct: 167 ERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDR 226

Query: 315 NCESRRRKERDGERHHSHK 333
               R ++    ER    K
Sbjct: 227 QTNWREKERGKRERKERKK 245



 Score = 29.3 bits (64), Expect = 5.3
 Identities = 26/144 (18%), Positives = 55/144 (38%), Gaps = 2/144 (1%)

Query: 195 KINQDNSRKSPKSYLEILAEVRDYKRRRQSYRAKNVHITKKSYTEVIRDVINVHMEELSN 254
           K N++   K  +   E     R  K  ++  R +     ++   E  ++      E    
Sbjct: 104 KENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKER 163

Query: 255 HWQEEQEKAEDDAEKNEERRSASVDSRQSGGSYLDAECSRHRRDRSRSPHKRKRNKDKDK 314
             +E ++  E + E+ E+ R      R+        E  R  R   +   K+K  + K++
Sbjct: 164 KKRERKQVGEKEEERKEKERKER-KKRERNRKERKKERERKERRERKKERKKKEERKKER 222

Query: 315 NCESRRRKERDGERHHSHKRRKQK 338
             + R+   R+ ER    ++ ++K
Sbjct: 223 Q-KDRQTNWREKERGKRERKERKK 245


>gi|239747174 PREDICTED: hypothetical protein XP_002343931, partial
           [Homo sapiens]
          Length = 213

 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 28/131 (21%), Positives = 61/131 (46%), Gaps = 8/131 (6%)

Query: 216 RDYKRRRQSYRAKNVHITKKSYTEVIRDVINVHMEELSNHWQEEQEKAED-------DAE 268
           RD  R+R++ R ++       +TE  R+       E+      E+EK ++       D E
Sbjct: 80  RDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTDRE 139

Query: 269 KNEERRSASVDSRQSGGSYLDAECSRHR-RDRSRSPHKRKRNKDKDKNCESRRRKERDGE 327
            + ER   +   R++G      +  R R R+R R   +++  K+++++ +  R ++R+ +
Sbjct: 140 TDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKERERHTDMERERQRETD 199

Query: 328 RHHSHKRRKQK 338
           R    +R  ++
Sbjct: 200 RKRDRQRESER 210



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 26/92 (28%), Positives = 44/92 (47%), Gaps = 10/92 (10%)

Query: 257 QEEQEKAEDDAEKNEERRSASVDSRQSGGSYLDAECSRHR-RDRSRSPH---------KR 306
           ++ + + E D E++  + S + D         D E +R R RDR R            +R
Sbjct: 19  RQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRER 78

Query: 307 KRNKDKDKNCESRRRKERDGERHHSHKRRKQK 338
           +R++D+ +  E  R KER+ +RH    R +QK
Sbjct: 79  ERDRDRQRETERERDKERETDRHTETDRERQK 110



 Score = 32.7 bits (73), Expect = 0.48
 Identities = 35/135 (25%), Positives = 59/135 (43%), Gaps = 19/135 (14%)

Query: 216 RDYKRRRQSYRAKNVHITKKSYTEVIRDVINVHMEELSNHWQEEQEKAEDDAEKNEERRS 275
           RD +R R+  R ++    ++  T+  R+       E     Q E E+ E D E+  +R +
Sbjct: 46  RDRQRDRERNRERDRDREREKQTD--REGERQRERERDRDRQRETER-ERDKERETDRHT 102

Query: 276 ASVDSRQSGGSYLDAECSRHRRDRSRSPHK---RKRNKDKDKNCESRRRKERDGE----- 327
            +   RQ      + E  R R DR R   K   R+R  D++ + E  R+ ER+ E     
Sbjct: 103 ETDRERQK---QKEREMERVR-DREREKQKEMGRERQTDRETDRERERQAERERETGRER 158

Query: 328 ----RHHSHKRRKQK 338
               RH   +R +++
Sbjct: 159 KTEDRHRERERERKR 173


>gi|29568103 U1 small nuclear ribonucleoprotein 70 kDa [Homo
           sapiens]
          Length = 437

 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 25/92 (27%), Positives = 44/92 (47%), Gaps = 12/92 (13%)

Query: 248 HMEELSNHWQEEQEKAEDDAEKNEERRSASVDSRQSGGSYLDAECSRHRRDRSRSPHKRK 307
           H +   +  +E +E++ +  ++ E RRS S D R            R  R R +   +R 
Sbjct: 230 HRDRDRDRERERRERSRERDKERERRRSRSRDRR------------RRSRSRDKEERRRS 277

Query: 308 RNKDKDKNCESRRRKERDGERHHSHKRRKQKI 339
           R + KDK+ + +RR  R  ER    + RK+++
Sbjct: 278 RERSKDKDRDRKRRSSRSRERARRERERKEEL 309



 Score = 30.4 bits (67), Expect = 2.4
 Identities = 33/160 (20%), Positives = 59/160 (36%), Gaps = 31/160 (19%)

Query: 198 QDNSRKSPKSYLEILAEVRDYKRRRQSYRAKNVHITKKSYTEVIRDVINVHMEELSNHWQ 257
           ++ SR+  K      +  RD +RR +S   +    +++   +  RD              
Sbjct: 242 RERSRERDKERERRRSRSRDRRRRSRSRDKEERRRSRERSKDKDRD--------RKRRSS 293

Query: 258 EEQEKAEDDAEKNEERRSASVDSRQ----------------------SGGSYLDAECSRH 295
             +E+A  + E+ EE R    D  +                       G      +  R 
Sbjct: 294 RSRERARRERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGPEEKGRDRDRE 353

Query: 296 RRDRSRSPHKRKRNKDKDKNCE-SRRRKERDGERHHSHKR 334
           RR   RS  +R+R++D+D++ +   +R ER  ER     R
Sbjct: 354 RRRSHRSERERRRDRDRDRDRDREHKRGERGSERGRDEAR 393


>gi|169167715 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 285

 Score = 45.1 bits (105), Expect = 9e-05
 Identities = 42/178 (23%), Positives = 74/178 (41%), Gaps = 26/178 (14%)

Query: 171 ETKKKRSDSQIIENDSDLFVDLAAKINQDNSRKSPKSYLEILAEVRDYKRRRQSYRAKNV 230
           E ++KR+  +  E D ++  D   +  +D  R+  +         RD KR R   R +  
Sbjct: 67  ERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRD--------RDRKRERWGDRDRET 118

Query: 231 HITKKSYTEVIRDVINVHMEELSNHWQEEQEKAED-----DAEKNEERRSASVDSRQSGG 285
              ++   E  RD       E     Q ++E   D     + EK+ +R     ++ +   
Sbjct: 119 ETERQEERERQRD----RKREKDRERQRQREIGIDKDREIETEKDRDREREMGETER--- 171

Query: 286 SYLDAECSRH-----RRDRSRSPHKRKRNKDKDKNCESRRRKERDGERHHSHKRRKQK 338
            Y D E  R      RRDR R   + K ++++D++ +  R K+R  ER     R K++
Sbjct: 172 -YRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKER 228



 Score = 36.6 bits (83), Expect = 0.033
 Identities = 25/82 (30%), Positives = 40/82 (48%), Gaps = 6/82 (7%)

Query: 257 QEEQEKAEDDAEKNEERRSASVDSRQSGGSYLDAECSRHRRDRSRSPHKRKRNKDKDKNC 316
           Q E+E+    A++    +   ++  +      D E  R R DR R   KR+R  D+D+  
Sbjct: 63  QRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWR-DRDR---KRERWGDRDRET 118

Query: 317 ESRRRKERDGERHHSHKRRKQK 338
           E+ R++ER  ER    KR K +
Sbjct: 119 ETERQEER--ERQRDRKREKDR 138



 Score = 36.6 bits (83), Expect = 0.033
 Identities = 31/136 (22%), Positives = 57/136 (41%), Gaps = 14/136 (10%)

Query: 199 DNSRKSPKSYLEILAEVRDYKRR--RQSYRAKNVHITKKSYTEVIRDVINVH----MEEL 252
           D  R++     E     RD KR   R+  R + + I K    E  +D          E  
Sbjct: 113 DRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERY 172

Query: 253 SNHWQEEQEKAEDDAEKNEERRSASVDSRQSGGSYLDAECSRHRRDRSRSPHKRKRNKDK 312
            +  +E Q++ E   +++ ER+    D  +      + E  R+R        +R+  +D+
Sbjct: 173 RDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYR--------ERETGRDR 224

Query: 313 DKNCESRRRKERDGER 328
           DK  +  R++E+D +R
Sbjct: 225 DKERDRERQREKDRDR 240


>gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 202

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 32/125 (25%), Positives = 56/125 (44%), Gaps = 4/125 (3%)

Query: 216 RDYKRRRQSYRAKNVHITKKSYTEVIRDVINVHMEELSNHWQEEQEKAEDDAEKNEERRS 275
           R+ +R RQ  R +     +++  E  R        E       E++K  D   K E  R+
Sbjct: 52  REKERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRN 111

Query: 276 ASVDSRQSGGSYLDAECSRHR-RDRSRS-PHKRKRNKDKDKNCESRRRKERDGERHHSHK 333
              +  + GG   D +  R R R+R R    +R+R + +++  E+ R ++R  ER    K
Sbjct: 112 R--ERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKK 169

Query: 334 RRKQK 338
            RK++
Sbjct: 170 ERKKE 174



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 33/128 (25%), Positives = 55/128 (42%), Gaps = 11/128 (8%)

Query: 216 RDYKRRRQSYRAKNVHITKKSYTEVIRDVINVHMEELSNHWQEEQEKAED---DAEKNEE 272
           R  +R+R++ R K     +    E          E  + H Q ++ +  D   D EK  E
Sbjct: 3   RQRERKRETDRGKETERERDRQRERENQT-----ERENRHRQRDRHRERDRQTDREKERE 57

Query: 273 RRSASVDSRQSGGSYLDAECSRHRRDRSRSPHKRK--RNKDKDKNCESRRRKERDGERHH 330
           R+      RQ      + E  R R  + +   KR+  R +DKD++ E +R  +R+ ER+ 
Sbjct: 58  RQKERDRQRQRERE-TERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNR 116

Query: 331 SHKRRKQK 338
              R + K
Sbjct: 117 KGGRERDK 124



 Score = 37.4 bits (85), Expect = 0.019
 Identities = 29/130 (22%), Positives = 58/130 (44%), Gaps = 13/130 (10%)

Query: 216 RDYKRRRQS-------YRAKNVHITKKSYTEVIRDVINVHMEELSNHWQEEQEKAEDDAE 268
           RD +R R++       +R ++ H  +   T+  R+      +E     Q E+E  E + E
Sbjct: 21  RDRQRERENQTERENRHRQRDRHRERDRQTD--REKERERQKERDRQRQRERE-TERETE 77

Query: 269 KNEERRSASVDSRQSGGSYLDAECSRHRRDRSRSPHKRKRNKDKDKNCESRRRKERDGER 328
           +  ER+      RQ+     + +  R R  +  +   R+RN+   +  + +  +ERD ER
Sbjct: 78  RQRERQRQRERKRQTDR---ERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRER 134

Query: 329 HHSHKRRKQK 338
               +R +++
Sbjct: 135 ERQRQRERER 144



 Score = 33.5 bits (75), Expect = 0.28
 Identities = 22/125 (17%), Positives = 48/125 (38%)

Query: 214 EVRDYKRRRQSYRAKNVHITKKSYTEVIRDVINVHMEELSNHWQEEQEKAEDDAEKNEER 273
           E R  +R R   R +     K+   +  RD       E     + ++E+      K +  
Sbjct: 34  ENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETERETERQRERQRQRERKRQTD 93

Query: 274 RSASVDSRQSGGSYLDAECSRHRRDRSRSPHKRKRNKDKDKNCESRRRKERDGERHHSHK 333
           R    D  +      D    R+R+       + +R +D+++  + +R +ER  +R    +
Sbjct: 94  RERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRE 153

Query: 334 RRKQK 338
             +++
Sbjct: 154 TDRER 158



 Score = 32.3 bits (72), Expect = 0.62
 Identities = 22/109 (20%), Positives = 43/109 (39%)

Query: 216 RDYKRRRQSYRAKNVHITKKSYTEVIRDVINVHMEELSNHWQEEQEKAEDDAEKNEERRS 275
           R+ KR+    R K+    +K  T+  R+       E     + E+++  +   + E  R 
Sbjct: 86  RERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQ 145

Query: 276 ASVDSRQSGGSYLDAECSRHRRDRSRSPHKRKRNKDKDKNCESRRRKER 324
              + ++           R  R + R   ++K  K+K K  + R  K+R
Sbjct: 146 RQRERKRETDRERQRWAEREERKKERKKERKKERKEKKKEEKRREDKKR 194


>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
           [Homo sapiens]
          Length = 624

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 34/143 (23%), Positives = 66/143 (46%), Gaps = 7/143 (4%)

Query: 197 NQDNSRKSPKSYLEILAEVRDYKRRRQSYRAKNVHITKKSYTEVIRDVINVHMEELSNHW 256
           N+  SR+  +   +   + R   R R+  R+++    K+  T   R+ I    E +    
Sbjct: 339 NRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDT---REKIK-EKERVKEKD 394

Query: 257 QEEQEKAEDDAEKNEER-RSASVDSRQSGGSYLDAECSRHRRDRSRSPHKRKRNKDKDKN 315
           +E++ + E + EK +ER ++   D  +      D E  R R       H++ R+K+K+K 
Sbjct: 395 REKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKE--HEKDRDKEKEKE 452

Query: 316 CESRRRKERDGERHHSHKRRKQK 338
            +  + +E+D  +    KR+K K
Sbjct: 453 QDKEKEREKDRSKEIDEKRKKDK 475



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 41/180 (22%), Positives = 80/180 (44%), Gaps = 20/180 (11%)

Query: 173 KKKRSDSQIIENDSDLFVDLAAKINQDNSRKSPKSYLEILAEVRDYKRRRQSYRAKNVHI 232
           K+K +  +I E +     D   +  ++  R+  K   +     ++ ++ R+  + K+   
Sbjct: 376 KRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRER 435

Query: 233 TKKSYTEVIRDVINVHMEELSNHWQEEQEKAEDDAEKNEERRSASVDSRQSGGSY----L 288
            ++   E  RD      +E      +E+E+ +D +++ +E+R     SR    SY     
Sbjct: 436 EREKEHEKDRD------KEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRR 489

Query: 289 DAECSRHRRDR-----SRSPH-----KRKRNKDKDKNCESRRRKERDGERHHSHKRRKQK 338
               SR RR R     SRSP      KRK ++       +++ K+R+ ER H  +RR+++
Sbjct: 490 SRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERE 549



 Score = 38.9 bits (89), Expect = 0.007
 Identities = 48/214 (22%), Positives = 76/214 (35%), Gaps = 43/214 (20%)

Query: 151 RFVCDLTQADRLALYDFVVEETKKKRSDSQIIENDSDLFVDLAAKINQDNS------RKS 204
           R   D TQ  R A  +F       + S  + +  +  +F D   KIN  N+        +
Sbjct: 213 RMAGDETQPTRFAFVEFA-----DQNSVPRALAFNGVMFGDRPLKINHSNNAIVKPPEMT 267

Query: 205 PKSYLEILAEVRDYKRRRQSYRAKNVHITKKSYTEVIRDVINVHMEELSNHWQEEQEKAE 264
           P++  + L EV    R  QS+            +  I        E      +       
Sbjct: 268 PQAAAKELEEVMKRVREAQSF-----------ISAAIEPESGKSNERKGGRSRSHTRSKS 316

Query: 265 DDAEKNEERRSASVDSRQSGGSYLDAECSRHRRDRSRSPH-------------------- 304
             + K+  RR  S  S+    S+  +   +  R RS+SPH                    
Sbjct: 317 RSSSKSHSRRKRS-QSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRD 375

Query: 305 KRKRNKDKDKNCESRRRKERDGERHHSHKRRKQK 338
           KRK  ++K K  E  + K+R+ ER    +R K+K
Sbjct: 376 KRKDTREKIKEKERVKEKDREKEREREKEREKEK 409



 Score = 38.1 bits (87), Expect = 0.011
 Identities = 52/203 (25%), Positives = 77/203 (37%), Gaps = 50/203 (24%)

Query: 171 ETKKKRSDSQIIENDSDLFVDLAAKINQDNSRKSPKSYLEILAEVRDYKRRRQSYRAKNV 230
           E +K RS S    +  D   D   KI +    K      E     R+ +R ++  R KN 
Sbjct: 363 ERRKSRSRS----HSRDKRKDTREKIKEKERVKEKDREKE---REREKEREKEKERGKNK 415

Query: 231 HITKKSYTEVIRDVINVHMEELSNHWQE----EQEKAEDDAEKNEERRSASVDSRQS--- 283
              K+   +  +D       E     ++    E+EK +D  ++ E+ RS  +D ++    
Sbjct: 416 DRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDK 475

Query: 284 ---------GGSYLDAECSRHRRDR-------------------SRSPHKRKRNKDKDKN 315
                      S      SR RR R                   SRSP  R RNK KDK 
Sbjct: 476 KSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNK-KDK- 533

Query: 316 CESRRRKERDGERHHSHKRRKQK 338
              +R KERD   H S +R +++
Sbjct: 534 ---KREKERD---HISERRERER 550



 Score = 37.0 bits (84), Expect = 0.025
 Identities = 30/140 (21%), Positives = 53/140 (37%), Gaps = 4/140 (2%)

Query: 201 SRKSPKSYLEILAEVRDYKRRRQSYRAKNVHITKKSYTEVIRDVINVHMEELSNHWQEEQ 260
           SR   +S     ++    ++R QS      H   +S  +  R   + H +   +  + + 
Sbjct: 308 SRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKS 367

Query: 261 EKAEDDAEKNEERRSASVDSRQSGGSYLDAECSRHRRDRSRSPHKRKRNKDKDKNCESRR 320
                  +K ++ R    +  +      D E  R R        +R +NKD+DK  E  R
Sbjct: 368 RSRSHSRDKRKDTREKIKEKERVKEK--DREKEREREKEREKEKERGKNKDRDKEREKDR 425

Query: 321 RK--ERDGERHHSHKRRKQK 338
            K  E+D ER    +  K +
Sbjct: 426 EKDKEKDREREREKEHEKDR 445



 Score = 33.1 bits (74), Expect = 0.36
 Identities = 30/131 (22%), Positives = 53/131 (40%), Gaps = 12/131 (9%)

Query: 216 RDYKRRRQSYRAKNVHITKKSYTEVIRDVINVHMEELSNHWQEEQEKAEDDAEKNEERRS 275
           +D +R R+    K+    K+   +  ++      +E+    +++++        N  RRS
Sbjct: 431 KDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRS 490

Query: 276 ASVD-------SRQSGGSYLDAECSRHRRDRSRSPHKR-----KRNKDKDKNCESRRRKE 323
            S         SR S  S   ++  + +  RS SP  R     KR K++D   E R R+ 
Sbjct: 491 RSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERER 550

Query: 324 RDGERHHSHKR 334
               R  S+ R
Sbjct: 551 STSMRKSSNDR 561



 Score = 30.4 bits (67), Expect = 2.4
 Identities = 33/164 (20%), Positives = 63/164 (38%), Gaps = 33/164 (20%)

Query: 170 EETKKKRSDSQIIENDSDLFVDLAAKINQDNSRKSPKSYLEILAEVRDYKRRRQSYRAKN 229
           ++ K+K  D +  E + D   ++  K  +D   ++P          R   R R+  R+++
Sbjct: 446 DKEKEKEQDKEK-EREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRS 504

Query: 230 VHITKKSYTEVIRDVINVHMEELSNHWQEEQEKAEDDAEKNEERRSASVDSRQSGGSYLD 289
              + ++   + R          S+     + + + D ++ +ER   S            
Sbjct: 505 SSRSPRTSKTIKRK---------SSRSPSPRSRNKKDKKREKERDHIS------------ 543

Query: 290 AECSRHRRDRSRSPHKRKRNKDKD------KNCESRRRKERDGE 327
                 RR+R RS   RK + D+D      KN  S + KE + E
Sbjct: 544 -----ERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKE 582


>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
           [Homo sapiens]
          Length = 508

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 34/143 (23%), Positives = 66/143 (46%), Gaps = 7/143 (4%)

Query: 197 NQDNSRKSPKSYLEILAEVRDYKRRRQSYRAKNVHITKKSYTEVIRDVINVHMEELSNHW 256
           N+  SR+  +   +   + R   R R+  R+++    K+  T   R+ I    E +    
Sbjct: 223 NRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDT---REKIK-EKERVKEKD 278

Query: 257 QEEQEKAEDDAEKNEER-RSASVDSRQSGGSYLDAECSRHRRDRSRSPHKRKRNKDKDKN 315
           +E++ + E + EK +ER ++   D  +      D E  R R       H++ R+K+K+K 
Sbjct: 279 REKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKE--HEKDRDKEKEKE 336

Query: 316 CESRRRKERDGERHHSHKRRKQK 338
            +  + +E+D  +    KR+K K
Sbjct: 337 QDKEKEREKDRSKEIDEKRKKDK 359



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 41/180 (22%), Positives = 80/180 (44%), Gaps = 20/180 (11%)

Query: 173 KKKRSDSQIIENDSDLFVDLAAKINQDNSRKSPKSYLEILAEVRDYKRRRQSYRAKNVHI 232
           K+K +  +I E +     D   +  ++  R+  K   +     ++ ++ R+  + K+   
Sbjct: 260 KRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRER 319

Query: 233 TKKSYTEVIRDVINVHMEELSNHWQEEQEKAEDDAEKNEERRSASVDSRQSGGSY----L 288
            ++   E  RD      +E      +E+E+ +D +++ +E+R     SR    SY     
Sbjct: 320 EREKEHEKDRD------KEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRR 373

Query: 289 DAECSRHRRDR-----SRSPH-----KRKRNKDKDKNCESRRRKERDGERHHSHKRRKQK 338
               SR RR R     SRSP      KRK ++       +++ K+R+ ER H  +RR+++
Sbjct: 374 SRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERE 433



 Score = 38.9 bits (89), Expect = 0.007
 Identities = 48/214 (22%), Positives = 76/214 (35%), Gaps = 43/214 (20%)

Query: 151 RFVCDLTQADRLALYDFVVEETKKKRSDSQIIENDSDLFVDLAAKINQDNS------RKS 204
           R   D TQ  R A  +F       + S  + +  +  +F D   KIN  N+        +
Sbjct: 97  RMAGDETQPTRFAFVEFA-----DQNSVPRALAFNGVMFGDRPLKINHSNNAIVKPPEMT 151

Query: 205 PKSYLEILAEVRDYKRRRQSYRAKNVHITKKSYTEVIRDVINVHMEELSNHWQEEQEKAE 264
           P++  + L EV    R  QS+            +  I        E      +       
Sbjct: 152 PQAAAKELEEVMKRVREAQSF-----------ISAAIEPESGKSNERKGGRSRSHTRSKS 200

Query: 265 DDAEKNEERRSASVDSRQSGGSYLDAECSRHRRDRSRSPH-------------------- 304
             + K+  RR  S  S+    S+  +   +  R RS+SPH                    
Sbjct: 201 RSSSKSHSRRKRS-QSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRD 259

Query: 305 KRKRNKDKDKNCESRRRKERDGERHHSHKRRKQK 338
           KRK  ++K K  E  + K+R+ ER    +R K+K
Sbjct: 260 KRKDTREKIKEKERVKEKDREKEREREKEREKEK 293



 Score = 38.1 bits (87), Expect = 0.011
 Identities = 52/203 (25%), Positives = 77/203 (37%), Gaps = 50/203 (24%)

Query: 171 ETKKKRSDSQIIENDSDLFVDLAAKINQDNSRKSPKSYLEILAEVRDYKRRRQSYRAKNV 230
           E +K RS S    +  D   D   KI +    K      E     R+ +R ++  R KN 
Sbjct: 247 ERRKSRSRS----HSRDKRKDTREKIKEKERVKEKDREKE---REREKEREKEKERGKNK 299

Query: 231 HITKKSYTEVIRDVINVHMEELSNHWQE----EQEKAEDDAEKNEERRSASVDSRQS--- 283
              K+   +  +D       E     ++    E+EK +D  ++ E+ RS  +D ++    
Sbjct: 300 DRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDK 359

Query: 284 ---------GGSYLDAECSRHRRDR-------------------SRSPHKRKRNKDKDKN 315
                      S      SR RR R                   SRSP  R RNK KDK 
Sbjct: 360 KSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNK-KDK- 417

Query: 316 CESRRRKERDGERHHSHKRRKQK 338
              +R KERD   H S +R +++
Sbjct: 418 ---KREKERD---HISERRERER 434



 Score = 37.0 bits (84), Expect = 0.025
 Identities = 30/140 (21%), Positives = 53/140 (37%), Gaps = 4/140 (2%)

Query: 201 SRKSPKSYLEILAEVRDYKRRRQSYRAKNVHITKKSYTEVIRDVINVHMEELSNHWQEEQ 260
           SR   +S     ++    ++R QS      H   +S  +  R   + H +   +  + + 
Sbjct: 192 SRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKS 251

Query: 261 EKAEDDAEKNEERRSASVDSRQSGGSYLDAECSRHRRDRSRSPHKRKRNKDKDKNCESRR 320
                  +K ++ R    +  +      D E  R R        +R +NKD+DK  E  R
Sbjct: 252 RSRSHSRDKRKDTREKIKEKERVKEK--DREKEREREKEREKEKERGKNKDRDKEREKDR 309

Query: 321 RK--ERDGERHHSHKRRKQK 338
            K  E+D ER    +  K +
Sbjct: 310 EKDKEKDREREREKEHEKDR 329



 Score = 33.1 bits (74), Expect = 0.36
 Identities = 30/131 (22%), Positives = 53/131 (40%), Gaps = 12/131 (9%)

Query: 216 RDYKRRRQSYRAKNVHITKKSYTEVIRDVINVHMEELSNHWQEEQEKAEDDAEKNEERRS 275
           +D +R R+    K+    K+   +  ++      +E+    +++++        N  RRS
Sbjct: 315 KDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRS 374

Query: 276 ASVD-------SRQSGGSYLDAECSRHRRDRSRSPHKR-----KRNKDKDKNCESRRRKE 323
            S         SR S  S   ++  + +  RS SP  R     KR K++D   E R R+ 
Sbjct: 375 RSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERER 434

Query: 324 RDGERHHSHKR 334
               R  S+ R
Sbjct: 435 STSMRKSSNDR 445



 Score = 30.4 bits (67), Expect = 2.4
 Identities = 33/164 (20%), Positives = 63/164 (38%), Gaps = 33/164 (20%)

Query: 170 EETKKKRSDSQIIENDSDLFVDLAAKINQDNSRKSPKSYLEILAEVRDYKRRRQSYRAKN 229
           ++ K+K  D +  E + D   ++  K  +D   ++P          R   R R+  R+++
Sbjct: 330 DKEKEKEQDKEK-EREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRS 388

Query: 230 VHITKKSYTEVIRDVINVHMEELSNHWQEEQEKAEDDAEKNEERRSASVDSRQSGGSYLD 289
              + ++   + R          S+     + + + D ++ +ER   S            
Sbjct: 389 SSRSPRTSKTIKRK---------SSRSPSPRSRNKKDKKREKERDHIS------------ 427

Query: 290 AECSRHRRDRSRSPHKRKRNKDKD------KNCESRRRKERDGE 327
                 RR+R RS   RK + D+D      KN  S + KE + E
Sbjct: 428 -----ERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKE 466


>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
          Length = 780

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 43/173 (24%), Positives = 66/173 (38%), Gaps = 14/173 (8%)

Query: 166 DFVVEETKKKRSDSQIIENDSDLFVDLAAKINQDNSRKSPKSYLEILAEVRDYKRRRQSY 225
           +  +  +  +R DS     + D    LA K  Q  SRK    + +   E R  K R  S+
Sbjct: 59  EITIRNSPYRREDSMEDRGEED--DSLAIKPPQQMSRKEKVHHRK--DEKRKEKCRHHSH 114

Query: 226 RAKNVHITKKSYTEVIRDVINVHMEELSNHWQEEQEKAEDDAEKNEERRSASVDSRQSGG 285
            A+     +    E           E     +EEQ+KA  + E+ + R  A   SR+   
Sbjct: 115 SAEGGKHARVKERE----------HERRKRHREEQDKARREWERQKRREMAREHSRRERD 164

Query: 286 SYLDAECSRHRRDRSRSPHKRKRNKDKDKNCESRRRKERDGERHHSHKRRKQK 338
                E  R R  + R   K +R + + +     RRKER+  R  S   R  +
Sbjct: 165 RLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMR 217



 Score = 31.6 bits (70), Expect = 1.1
 Identities = 20/70 (28%), Positives = 31/70 (44%), Gaps = 1/70 (1%)

Query: 257 QEEQEKAEDDAEKNEERRSASVDSRQSGGSYLD-AECSRHRRDRSRSPHKRKRNKDKDKN 315
           +E + +AE+  ++ E RR  S   R     Y D  + S   R   R P +R    D  K 
Sbjct: 190 KERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKP 249

Query: 316 CESRRRKERD 325
            +  + +ERD
Sbjct: 250 VKEEKMEERD 259



 Score = 31.2 bits (69), Expect = 1.4
 Identities = 26/93 (27%), Positives = 42/93 (45%), Gaps = 19/93 (20%)

Query: 257 QEEQEKAEDDAEKNEERRSASVDSRQSGG-----SYLDAECSRHRRDRSR---------- 301
           +E++EKAE    KN + R +  DS + G        +    S +RR+ S           
Sbjct: 24  KEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRGEEDDSL 83

Query: 302 --SPHKRKRNKDKDKNCESRRRKERDGERHHSH 332
              P ++   K+K  + +  +RKE+   RHHSH
Sbjct: 84  AIKPPQQMSRKEKVHHRKDEKRKEKC--RHHSH 114


>gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3
           [Homo sapiens]
          Length = 1125

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 29/110 (26%), Positives = 56/110 (50%), Gaps = 13/110 (11%)

Query: 224 SYRAKNVHITKKSYTEVIRDVINVHMEELSNHWQEEQEKAEDDAEKNEERRSASVDSRQS 283
           S++A+N  +T+K + + + +V    ++E+  H  + ++     A ++ +RR +   SR  
Sbjct: 397 SFQAQNEPLTQKPHQQEM-EVEQPCIQEVKRHMSDNRKSRSRSASRSPKRRRSRSGSR-- 453

Query: 284 GGSYLDAECSRHRRDRSRSPHKRKRNKDKDKNCESRRRKERDGERHHSHK 333
                 +  SRHRR RSRS  +R+ +        S+ R++R+ ER    K
Sbjct: 454 ------SRRSRHRRSRSRSRDRRRHS----PRSRSQERRDREKERERRQK 493



 Score = 30.8 bits (68), Expect = 1.8
 Identities = 23/70 (32%), Positives = 38/70 (54%), Gaps = 12/70 (17%)

Query: 262  KAEDDAEK----NEERRSASVDSRQSGGSYLDAECSRHR----RDRSRSPHKRKRNKDKD 313
            + E+D E+    N++R +++ D R+ G    D +  RHR    R+R  S H+ +    +D
Sbjct: 986  RVENDRERYGNRNDDRDNSNRDRREWGRRSPDRD--RHRDLEERNRRSSGHRDRERDSRD 1043

Query: 314  KNCESRRRKE 323
            +  ESRR KE
Sbjct: 1044 R--ESRREKE 1051


>gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2
           [Homo sapiens]
          Length = 1132

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 29/110 (26%), Positives = 56/110 (50%), Gaps = 13/110 (11%)

Query: 224 SYRAKNVHITKKSYTEVIRDVINVHMEELSNHWQEEQEKAEDDAEKNEERRSASVDSRQS 283
           S++A+N  +T+K + + + +V    ++E+  H  + ++     A ++ +RR +   SR  
Sbjct: 382 SFQAQNEPLTQKPHQQEM-EVEQPCIQEVKRHMSDNRKSRSRSASRSPKRRRSRSGSR-- 438

Query: 284 GGSYLDAECSRHRRDRSRSPHKRKRNKDKDKNCESRRRKERDGERHHSHK 333
                 +  SRHRR RSRS  +R+ +        S+ R++R+ ER    K
Sbjct: 439 ------SRRSRHRRSRSRSRDRRRHS----PRSRSQERRDREKERERRQK 478



 Score = 30.8 bits (68), Expect = 1.8
 Identities = 23/70 (32%), Positives = 38/70 (54%), Gaps = 12/70 (17%)

Query: 262  KAEDDAEK----NEERRSASVDSRQSGGSYLDAECSRHR----RDRSRSPHKRKRNKDKD 313
            + E+D E+    N++R +++ D R+ G    D +  RHR    R+R  S H+ +    +D
Sbjct: 993  RVENDRERYGNRNDDRDNSNRDRREWGRRSPDRD--RHRDLEERNRRSSGHRDRERDSRD 1050

Query: 314  KNCESRRRKE 323
            +  ESRR KE
Sbjct: 1051 R--ESRREKE 1058


>gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1
           [Homo sapiens]
          Length = 1147

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 29/110 (26%), Positives = 56/110 (50%), Gaps = 13/110 (11%)

Query: 224 SYRAKNVHITKKSYTEVIRDVINVHMEELSNHWQEEQEKAEDDAEKNEERRSASVDSRQS 283
           S++A+N  +T+K + + + +V    ++E+  H  + ++     A ++ +RR +   SR  
Sbjct: 397 SFQAQNEPLTQKPHQQEM-EVEQPCIQEVKRHMSDNRKSRSRSASRSPKRRRSRSGSR-- 453

Query: 284 GGSYLDAECSRHRRDRSRSPHKRKRNKDKDKNCESRRRKERDGERHHSHK 333
                 +  SRHRR RSRS  +R+ +        S+ R++R+ ER    K
Sbjct: 454 ------SRRSRHRRSRSRSRDRRRHS----PRSRSQERRDREKERERRQK 493



 Score = 30.8 bits (68), Expect = 1.8
 Identities = 23/70 (32%), Positives = 38/70 (54%), Gaps = 12/70 (17%)

Query: 262  KAEDDAEK----NEERRSASVDSRQSGGSYLDAECSRHR----RDRSRSPHKRKRNKDKD 313
            + E+D E+    N++R +++ D R+ G    D +  RHR    R+R  S H+ +    +D
Sbjct: 1008 RVENDRERYGNRNDDRDNSNRDRREWGRRSPDRD--RHRDLEERNRRSSGHRDRERDSRD 1065

Query: 314  KNCESRRRKE 323
            +  ESRR KE
Sbjct: 1066 R--ESRREKE 1073


>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           9 [Homo sapiens]
          Length = 771

 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 42/173 (24%), Positives = 67/173 (38%), Gaps = 23/173 (13%)

Query: 166 DFVVEETKKKRSDSQIIENDSDLFVDLAAKINQDNSRKSPKSYLEILAEVRDYKRRRQSY 225
           +  +  +  +R DS     + D    LA K  Q  SRK      E +   +D KR+ +  
Sbjct: 59  EITIRNSPYRREDSMEDRGEED--DSLAIKPPQQMSRK------EKVHHRKDEKRKEK-- 108

Query: 226 RAKNVHITKKSYTEVIRDVINVHMEELSNHWQEEQEKAEDDAEKNEERRSASVDSRQSGG 285
             K+  + +K               E     +EEQ+KA  + E+ + R  A   SR+   
Sbjct: 109 --KHARVKEKE-----------REHERRKRHREEQDKARREWERQKRREMAREHSRRERD 155

Query: 286 SYLDAECSRHRRDRSRSPHKRKRNKDKDKNCESRRRKERDGERHHSHKRRKQK 338
                E  R R  + R   K +R + + +     RRKER+  R  S   R  +
Sbjct: 156 RLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMR 208



 Score = 35.0 bits (79), Expect = 0.096
 Identities = 36/142 (25%), Positives = 65/142 (45%), Gaps = 15/142 (10%)

Query: 206 KSYLEILAEVRDYKRRRQSYRAKNVHITKKSYTEVIRDVINVHMEELSNHWQE-----EQ 260
           K+  EIL E +  +R+ Q  +A+   +      +  RD  ++   EL +H  E       
Sbjct: 11  KTLDEILQEKK--RRKEQEEKAEIKRLKNSDDRDSKRD--SLEEGELRDHCMEITIRNSP 66

Query: 261 EKAEDDAE-KNEERRSASVDSRQSGGSYLDAECSRHRRDRSRSPHKRKRNKDKDKNCESR 319
            + ED  E + EE  S ++   Q        E   HR+D  R   K  R K+K++  E R
Sbjct: 67  YRREDSMEDRGEEDDSLAIKPPQQMSR---KEKVHHRKDEKRKEKKHARVKEKEREHERR 123

Query: 320 RR--KERDGERHHSHKRRKQKI 339
           +R  +E+D  R    +++++++
Sbjct: 124 KRHREEQDKARREWERQKRREM 145



 Score = 31.6 bits (70), Expect = 1.1
 Identities = 20/70 (28%), Positives = 31/70 (44%), Gaps = 1/70 (1%)

Query: 257 QEEQEKAEDDAEKNEERRSASVDSRQSGGSYLD-AECSRHRRDRSRSPHKRKRNKDKDKN 315
           +E + +AE+  ++ E RR  S   R     Y D  + S   R   R P +R    D  K 
Sbjct: 181 KERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKP 240

Query: 316 CESRRRKERD 325
            +  + +ERD
Sbjct: 241 VKEEKMEERD 250


>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           4 [Homo sapiens]
          Length = 737

 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 42/173 (24%), Positives = 67/173 (38%), Gaps = 23/173 (13%)

Query: 166 DFVVEETKKKRSDSQIIENDSDLFVDLAAKINQDNSRKSPKSYLEILAEVRDYKRRRQSY 225
           +  +  +  +R DS     + D    LA K  Q  SRK      E +   +D KR+ +  
Sbjct: 25  EITIRNSPYRREDSMEDRGEED--DSLAIKPPQQMSRK------EKVHHRKDEKRKEK-- 74

Query: 226 RAKNVHITKKSYTEVIRDVINVHMEELSNHWQEEQEKAEDDAEKNEERRSASVDSRQSGG 285
             K+  + +K               E     +EEQ+KA  + E+ + R  A   SR+   
Sbjct: 75  --KHARVKEKE-----------REHERRKRHREEQDKARREWERQKRREMAREHSRRERD 121

Query: 286 SYLDAECSRHRRDRSRSPHKRKRNKDKDKNCESRRRKERDGERHHSHKRRKQK 338
                E  R R  + R   K +R + + +     RRKER+  R  S   R  +
Sbjct: 122 RLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMR 174



 Score = 31.6 bits (70), Expect = 1.1
 Identities = 20/70 (28%), Positives = 31/70 (44%), Gaps = 1/70 (1%)

Query: 257 QEEQEKAEDDAEKNEERRSASVDSRQSGGSYLD-AECSRHRRDRSRSPHKRKRNKDKDKN 315
           +E + +AE+  ++ E RR  S   R     Y D  + S   R   R P +R    D  K 
Sbjct: 147 KERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKP 206

Query: 316 CESRRRKERD 325
            +  + +ERD
Sbjct: 207 VKEEKMEERD 216



 Score = 31.2 bits (69), Expect = 1.4
 Identities = 22/81 (27%), Positives = 40/81 (49%), Gaps = 6/81 (7%)

Query: 262 KAEDDAE-KNEERRSASVDSRQSGGSYLDAECSRHRRDRSRSPHKRKRNKDKDKNCESRR 320
           + ED  E + EE  S ++   Q        E   HR+D  R   K  R K+K++  E R+
Sbjct: 34  RREDSMEDRGEEDDSLAIKPPQQMSR---KEKVHHRKDEKRKEKKHARVKEKEREHERRK 90

Query: 321 R--KERDGERHHSHKRRKQKI 339
           R  +E+D  R    +++++++
Sbjct: 91  RHREEQDKARREWERQKRREM 111



 Score = 29.3 bits (64), Expect = 5.3
 Identities = 32/149 (21%), Positives = 63/149 (42%), Gaps = 21/149 (14%)

Query: 196 INQDNSRKSPKSYLEILAEVRDYKR----RRQSYRAKNVHITKKSYTE--VIRDVINVHM 249
           ++Q + R S +  LE   E+RD++     R   YR ++    +    +   I+    +  
Sbjct: 1   MSQSDDRDSKRDSLEE-GELRDHRMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSR 59

Query: 250 EELSNHWQEEQEKAEDDAEKNEERRSASVDSRQSGGSYLDAECSRHRRDRSRSPHKRKRN 309
           +E  +H ++E+ K +  A   E+ R                   RHR ++ ++  + +R 
Sbjct: 60  KEKVHHRKDEKRKEKKHARVKEKEREHE-------------RRKRHREEQDKARREWERQ 106

Query: 310 KDKDKNCESRRRKERDGERHHSHKRRKQK 338
           K ++   E  RR ERD       KR +++
Sbjct: 107 KRREMAREHSRR-ERDRLEQLERKRERER 134


>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
           sapiens]
          Length = 434

 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 43/170 (25%), Positives = 75/170 (44%), Gaps = 20/170 (11%)

Query: 171 ETKKKRSDSQIIENDSDLFVDLAAKINQDNSRKSPKSYLEILAEVRDYKRRRQSYRAKNV 230
           + KK++S+  +    S      +   +++  RKS     +  +  R  + RR   + K+ 
Sbjct: 21  DKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKS- 79

Query: 231 HITKKSYTEVIRDVINVHMEELSNHWQEEQEKAE--DDAEKNEERRSASVDSRQSGGSYL 288
             +KK  +E   D      E  S+  +E    +E  +D  K +ER+S       S G   
Sbjct: 80  --SKKHKSEEHND-----KEHSSDKGRERLNSSENGEDRHKRKERKS-------SRGRSH 125

Query: 289 DAECSRHRRDRSRSPHKRKRNKDKDKNCESRRRKERDGERHHSHKRRKQK 338
               SR RR RSRS   R+R K + ++ E ++ + R  ER  S  R +++
Sbjct: 126 SRSRSRERRHRSRS---RERKKSRSRSRERKKSRSRSRERKKSRSRSRER 172



 Score = 38.9 bits (89), Expect = 0.007
 Identities = 32/147 (21%), Positives = 64/147 (43%), Gaps = 8/147 (5%)

Query: 195 KINQDNSRKSPKSYLEILAEVRDYKRRRQSYRAKNVHITKKSYTEVIRDVINVHMEELSN 254
           K + D  +K  +S  E+    R  K      R+++    +KS  E  +       +E   
Sbjct: 15  KTSPDRDKKKEQS--EVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRR 72

Query: 255 HWQEEQEKAEDDAEKNEERRSASVDSRQSGGSYLDAECSRHRRDRSRS---PHKRKRNKD 311
           H  +++   +  +E++ ++  +S   R+   S  + E    R++R  S    H R R+++
Sbjct: 73  HESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRE 132

Query: 312 KDKNCESRRRKERDGERHHSHKRRKQK 338
           +     SR RK+    R  S +R+K +
Sbjct: 133 RRHRSRSRERKK---SRSRSRERKKSR 156



 Score = 37.7 bits (86), Expect = 0.015
 Identities = 25/88 (28%), Positives = 42/88 (47%), Gaps = 11/88 (12%)

Query: 261 EKAEDDAEKNEERRSASVDSRQSGGSYLDAEC----------SRHRRDRSRSPHKR-KRN 309
           EK   D +K +E+   SV  R S   Y  +            +  R+ RSRS  K  +R+
Sbjct: 14  EKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRH 73

Query: 310 KDKDKNCESRRRKERDGERHHSHKRRKQ 337
           + KDK+ +  + +E + + H S K R++
Sbjct: 74  ESKDKSSKKHKSEEHNDKEHSSDKGRER 101


>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
          Length = 770

 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 39/173 (22%), Positives = 66/173 (38%), Gaps = 24/173 (13%)

Query: 166 DFVVEETKKKRSDSQIIENDSDLFVDLAAKINQDNSRKSPKSYLEILAEVRDYKRRRQSY 225
           +  +  +  +R DS     + D    LA K  Q  SRK          +V   K  ++  
Sbjct: 59  EITIRNSPYRREDSMEDRGEED--DSLAIKPPQQMSRKE---------KVHHRKDEKRKE 107

Query: 226 RAKNVHITKKSYTEVIRDVINVHMEELSNHWQEEQEKAEDDAEKNEERRSASVDSRQSGG 285
           + K+  + ++ +             E     +EEQ+KA  + E+ + R  A   SR+   
Sbjct: 108 KWKHARVKEREH-------------ERRKRHREEQDKARREWERQKRREMAREHSRRERD 154

Query: 286 SYLDAECSRHRRDRSRSPHKRKRNKDKDKNCESRRRKERDGERHHSHKRRKQK 338
                E  R R  + R   K +R + + +     RRKER+  R  S   R  +
Sbjct: 155 RLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMR 207



 Score = 31.6 bits (70), Expect = 1.1
 Identities = 20/70 (28%), Positives = 31/70 (44%), Gaps = 1/70 (1%)

Query: 257 QEEQEKAEDDAEKNEERRSASVDSRQSGGSYLD-AECSRHRRDRSRSPHKRKRNKDKDKN 315
           +E + +AE+  ++ E RR  S   R     Y D  + S   R   R P +R    D  K 
Sbjct: 180 KERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKP 239

Query: 316 CESRRRKERD 325
            +  + +ERD
Sbjct: 240 VKEEKMEERD 249



 Score = 31.2 bits (69), Expect = 1.4
 Identities = 29/109 (26%), Positives = 43/109 (39%), Gaps = 28/109 (25%)

Query: 257 QEEQEKAEDDAEKNEERRSASVDSRQSGG-----SYLDAECSRHRRD------------- 298
           +E++EKAE    KN + R +  DS + G        +    S +RR+             
Sbjct: 24  KEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRGEEDDSL 83

Query: 299 ---------RSRSPHKRKRNKDKDKNCESRRRKERDGERHHSHKRRKQK 338
                    R    H RK  K K+K  +  R KER+ ER   H+  + K
Sbjct: 84  AIKPPQQMSRKEKVHHRKDEKRKEK-WKHARVKEREHERRKRHREEQDK 131


>gi|4759098 splicing factor, arginine/serine-rich 10 [Homo sapiens]
          Length = 288

 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 24/75 (32%), Positives = 39/75 (52%), Gaps = 2/75 (2%)

Query: 265 DDAEKNEERRSASVDSRQSGGSYLDAECSRHRRDRSRSPHKRKRNKDKDKN-CESRRRKE 323
           D  E+N   R +   SR SG ++   + +RH   RSRS    +R++ K ++  ESR R  
Sbjct: 3   DSGEQNYGERESRSASR-SGSAHGSGKSARHTPARSRSKEDSRRSRSKSRSRSESRSRSR 61

Query: 324 RDGERHHSHKRRKQK 338
           R   RH++  R + +
Sbjct: 62  RSSRRHYTRSRSRSR 76



 Score = 30.0 bits (66), Expect = 3.1
 Identities = 21/67 (31%), Positives = 26/67 (38%), Gaps = 1/67 (1%)

Query: 267 AEKNEERRSASVDSRQSGGSYLDAECSRHRRDRSRSPH-KRKRNKDKDKNCESRRRKERD 325
           A     R  +  DSR+S         SR R  RS   H  R R++ +       R   RD
Sbjct: 30  ARHTPARSRSKEDSRRSRSKSRSRSESRSRSRRSSRRHYTRSRSRSRSHRRSRSRSYSRD 89

Query: 326 GERHHSH 332
             R HSH
Sbjct: 90  YRRRHSH 96


>gi|8922297 LUC7-like isoform a [Homo sapiens]
          Length = 325

 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 31/96 (32%), Positives = 44/96 (45%), Gaps = 5/96 (5%)

Query: 245 INVHMEELSNHWQEEQEKAEDDA-EKNEERRSASVDSRQSGGSYLDAECSR---HRRDRS 300
           I   +++L     E+QEK   D   + EER      SR+SG    D   SR    RR RS
Sbjct: 221 IREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRS 280

Query: 301 RSPHKRKRNKDKDKNCESRRRKERDGERHHSHKRRK 336
           RS  + +R   + ++   R R+ R   R HS   R+
Sbjct: 281 RSTSRERRKLSRSRS-RDRHRRHRSRSRSHSRGHRR 315



 Score = 32.0 bits (71), Expect = 0.81
 Identities = 54/270 (20%), Positives = 99/270 (36%), Gaps = 42/270 (15%)

Query: 110 LNKDSQFQIIKQARTAVGKDSDCYNQRIYSSLPVEVPLNHKRFVC--DLTQADRLALYDF 167
           ++  +Q + +        +D D   QR+  +    V  +H    C  D+    R+ L + 
Sbjct: 1   MSAQAQMRALLDQLMGTARDGDETRQRVKFT-DDRVCKSHLLDCCPHDILAGTRMDLGEC 59

Query: 168 VVEETKKKRSDSQIIENDSDLFVDLAAKINQDNSRKSPKSYLEI----LAEVRDYKRRRQ 223
                   R+D +I   + DLF +L A  + ++         E+    LAE ++      
Sbjct: 60  TKIHDLALRADYEIASKERDLFFELDAMDHLESFIAECDRRTELAKKRLAETQEEISAEV 119

Query: 224 SYRAKNVHITKKSYTEVIRDVINVHMEELSNHWQE-----EQEKAEDDAEKNEERRSASV 278
           S +A+ VH   +   +++     +  E   +  Q+     E+ +A+    + E R S   
Sbjct: 120 SAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPA 179

Query: 279 DSRQSGGSYLDAECSR----HRRDRSRSPH--------------------------KRKR 308
            S Q     +   CS     H  DR  + H                          + KR
Sbjct: 180 SSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKR 239

Query: 309 NKDKDKNCESRRRKERDGERHHSHKRRKQK 338
           N+D+ +  E R R+ER   R  S  R +++
Sbjct: 240 NQDRLRRREEREREERLSRRSGSRTRDRRR 269


>gi|42476169 Paf1, RNA polymerase II associated factor, homolog
           [Homo sapiens]
          Length = 531

 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 45/199 (22%), Positives = 78/199 (39%), Gaps = 31/199 (15%)

Query: 158 QADRLALYDFVVEETKKKRSDSQIIEND---SDLF-VDLAAKINQDNSRKSPKSYLE--- 210
           + ++   Y   VEET KKR   Q  E D    D++   +A + N +   K+ K Y E   
Sbjct: 253 EGNQFVAYFLPVEETLKKRKRDQEEEMDYAPDDVYDYKIAREYNWNVKNKASKGYEENYF 312

Query: 211 -------------ILAEVRDYKRRR----QSYRAKNVHITKKSYTEVIRDVINVHMEELS 253
                        +   VR  KRR     QS     + +  +   E   +       +L 
Sbjct: 313 FIFREGDGVYYNELETRVRLSKRRAKAGVQSGTNALLVVKHRDMNEKELEAQEARKAQLE 372

Query: 254 NHWQEEQEKAEDDAEKNE-------ERRSASVDSRQSGGSYLDAECSRHRRDRSRSPHKR 306
           NH  EE+E+ E + E+ E       + + +S +   S   +  +E  R   DR  +  K 
Sbjct: 373 NHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDKS 432

Query: 307 KRNKDKDKNCESRRRKERD 325
              +D+    E+R  ++++
Sbjct: 433 GSGEDESSEDEARAARDKE 451


>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
          Length = 2426

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 34/170 (20%), Positives = 63/170 (37%), Gaps = 1/170 (0%)

Query: 168  VVEETKKKRSDSQIIENDSDLFVDLAAKINQDNSRKSPKSYLEILAEVRDYKRRRQSYRA 227
            VV    ++ S+S   E D D  + +  K   + S+K+         + RD   R +S R+
Sbjct: 1771 VVSSMPERASESSSEEKD-DYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRS 1829

Query: 228  KNVHITKKSYTEVIRDVINVHMEELSNHWQEEQEKAEDDAEKNEERRSASVDSRQSGGSY 287
            K+     +  T   R        +  +H  + + ++     +   R  +    R+S    
Sbjct: 1830 KSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKE 1889

Query: 288  LDAECSRHRRDRSRSPHKRKRNKDKDKNCESRRRKERDGERHHSHKRRKQ 337
                  +HR        KR  ++D  K   +R R      R H+  RR++
Sbjct: 1890 KRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRR 1939



 Score = 37.4 bits (85), Expect = 0.019
 Identities = 38/165 (23%), Positives = 63/165 (38%), Gaps = 23/165 (13%)

Query: 192  LAAKINQDNSRKSP----------------KSYLEILAEVRDYKRRRQSYRAKNVHITKK 235
            LA+ + +D S  SP                K   EI  +V+D   + +  + ++     K
Sbjct: 1757 LASDVGRDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRD-----K 1811

Query: 236  SYTEVIRDVINVHMEELSNHWQEEQEKAEDDAEKNEERRSASVDSRQSGGSYLDAECSRH 295
               E  RD       + S   + +  K   ++     +RS+   S +S          R 
Sbjct: 1812 GEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRR 1871

Query: 296  R--RDRSRSPHKRKRNKDKDKNCESRRRKERDGERHHSHKRRKQK 338
            R  R RS+S  +R  +K+K K     R K R+ +R  S  R  +K
Sbjct: 1872 RSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRK 1916



 Score = 35.0 bits (79), Expect = 0.096
 Identities = 34/137 (24%), Positives = 56/137 (40%), Gaps = 14/137 (10%)

Query: 196  INQDNSRKSPKSYLEILAEVRDYKRRRQSYRAKNVHITKKSYTEVIRDVINVHMEELSNH 255
            ++++  ++SPK      ++ R+ KR+R S R     +  +S T   R           +H
Sbjct: 1886 VSKEKRKRSPKHR----SKSRERKRKRSSSRDNRKTVRARSRTPSRRS---------RSH 1932

Query: 256  WQEEQEKAEDDAEKNEERRSASVDSRQ-SGGSYLDAECSRHRRDRSRSPHKRKRNKDKDK 314
                + ++     +     S S  SR  S  S   +  SR    RSR+P +R R   +  
Sbjct: 1933 TPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRS 1992

Query: 315  NCESRRRKERDGERHHS 331
               SRRR+ R   R  S
Sbjct: 1993 RTPSRRRRSRSVVRRRS 2009


>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
          Length = 2303

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 34/170 (20%), Positives = 63/170 (37%), Gaps = 1/170 (0%)

Query: 168  VVEETKKKRSDSQIIENDSDLFVDLAAKINQDNSRKSPKSYLEILAEVRDYKRRRQSYRA 227
            VV    ++ S+S   E D D  + +  K   + S+K+         + RD   R +S R+
Sbjct: 1771 VVSSMPERASESSSEEKD-DYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRS 1829

Query: 228  KNVHITKKSYTEVIRDVINVHMEELSNHWQEEQEKAEDDAEKNEERRSASVDSRQSGGSY 287
            K+     +  T   R        +  +H  + + ++     +   R  +    R+S    
Sbjct: 1830 KSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKE 1889

Query: 288  LDAECSRHRRDRSRSPHKRKRNKDKDKNCESRRRKERDGERHHSHKRRKQ 337
                  +HR        KR  ++D  K   +R R      R H+  RR++
Sbjct: 1890 KRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRR 1939



 Score = 37.4 bits (85), Expect = 0.019
 Identities = 38/165 (23%), Positives = 63/165 (38%), Gaps = 23/165 (13%)

Query: 192  LAAKINQDNSRKSP----------------KSYLEILAEVRDYKRRRQSYRAKNVHITKK 235
            LA+ + +D S  SP                K   EI  +V+D   + +  + ++     K
Sbjct: 1757 LASDVGRDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRD-----K 1811

Query: 236  SYTEVIRDVINVHMEELSNHWQEEQEKAEDDAEKNEERRSASVDSRQSGGSYLDAECSRH 295
               E  RD       + S   + +  K   ++     +RS+   S +S          R 
Sbjct: 1812 GEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRR 1871

Query: 296  R--RDRSRSPHKRKRNKDKDKNCESRRRKERDGERHHSHKRRKQK 338
            R  R RS+S  +R  +K+K K     R K R+ +R  S  R  +K
Sbjct: 1872 RSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRK 1916



 Score = 35.0 bits (79), Expect = 0.096
 Identities = 34/137 (24%), Positives = 56/137 (40%), Gaps = 14/137 (10%)

Query: 196  INQDNSRKSPKSYLEILAEVRDYKRRRQSYRAKNVHITKKSYTEVIRDVINVHMEELSNH 255
            ++++  ++SPK      ++ R+ KR+R S R     +  +S T   R           +H
Sbjct: 1886 VSKEKRKRSPKHR----SKSRERKRKRSSSRDNRKTVRARSRTPSRRS---------RSH 1932

Query: 256  WQEEQEKAEDDAEKNEERRSASVDSRQ-SGGSYLDAECSRHRRDRSRSPHKRKRNKDKDK 314
                + ++     +     S S  SR  S  S   +  SR    RSR+P +R R   +  
Sbjct: 1933 TPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRS 1992

Query: 315  NCESRRRKERDGERHHS 331
               SRRR+ R   R  S
Sbjct: 1993 RTPSRRRRSRSVVRRRS 2009


>gi|41393554 LUC7-like isoform b [Homo sapiens]
          Length = 371

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 30/91 (32%), Positives = 37/91 (40%), Gaps = 1/91 (1%)

Query: 245 INVHMEELSNHWQEEQEKAEDDA-EKNEERRSASVDSRQSGGSYLDAECSRHRRDRSRSP 303
           I   +++L     E+QEK   D   + EER      SR+SG    D   SR R  R R  
Sbjct: 221 IREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRS 280

Query: 304 HKRKRNKDKDKNCESRRRKERDGERHHSHKR 334
               R + K     SR R  R   R  SH R
Sbjct: 281 RSTSRERRKLSRSRSRDRHRRHRSRSRSHSR 311



 Score = 32.0 bits (71), Expect = 0.81
 Identities = 54/270 (20%), Positives = 99/270 (36%), Gaps = 42/270 (15%)

Query: 110 LNKDSQFQIIKQARTAVGKDSDCYNQRIYSSLPVEVPLNHKRFVC--DLTQADRLALYDF 167
           ++  +Q + +        +D D   QR+  +    V  +H    C  D+    R+ L + 
Sbjct: 1   MSAQAQMRALLDQLMGTARDGDETRQRVKFT-DDRVCKSHLLDCCPHDILAGTRMDLGEC 59

Query: 168 VVEETKKKRSDSQIIENDSDLFVDLAAKINQDNSRKSPKSYLEI----LAEVRDYKRRRQ 223
                   R+D +I   + DLF +L A  + ++         E+    LAE ++      
Sbjct: 60  TKIHDLALRADYEIASKERDLFFELDAMDHLESFIAECDRRTELAKKRLAETQEEISAEV 119

Query: 224 SYRAKNVHITKKSYTEVIRDVINVHMEELSNHWQE-----EQEKAEDDAEKNEERRSASV 278
           S +A+ VH   +   +++     +  E   +  Q+     E+ +A+    + E R S   
Sbjct: 120 SAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPA 179

Query: 279 DSRQSGGSYLDAECSR----HRRDRSRSPH--------------------------KRKR 308
            S Q     +   CS     H  DR  + H                          + KR
Sbjct: 180 SSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKR 239

Query: 309 NKDKDKNCESRRRKERDGERHHSHKRRKQK 338
           N+D+ +  E R R+ER   R  S  R +++
Sbjct: 240 NQDRLRRREEREREERLSRRSGSRTRDRRR 269


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.129    0.365 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,670,006
Number of Sequences: 37866
Number of extensions: 633343
Number of successful extensions: 6292
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 174
Number of HSP's successfully gapped in prelim test: 309
Number of HSP's that attempted gapping in prelim test: 3760
Number of HSP's gapped (non-prelim): 1750
length of query: 339
length of database: 18,247,518
effective HSP length: 103
effective length of query: 236
effective length of database: 14,347,320
effective search space: 3385967520
effective search space used: 3385967520
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.