Search of human proteins with 13899259

Search of human proteins with 13899259

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|13899259 THAP domain containing, apoptosis associated
protein 2 [Homo sapiens]
         (228 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|13899259 THAP domain containing, apoptosis associated protein...   462   e-131
gi|8922446 THAP domain containing, apoptosis associated protein ...   105   4e-23
gi|42734379 THAP domain containing, apoptosis associated protein...    81   8e-16
gi|94536788 THAP domain containing 9 [Homo sapiens]                    74   8e-14
gi|21389507 THAP domain containing 6 [Homo sapiens]                    72   3e-13
gi|31982895 THAP domain containing 4 [Homo sapiens]                    68   6e-12
gi|194440668 THAP domain containing 5 isoform 1 [Homo sapiens]         68   7e-12
gi|19923268 protein-kinase, interferon-inducible double stranded...    66   3e-11
gi|56788351 THAP domain containing 7 isoform 2 [Homo sapiens]          63   2e-10
gi|56788349 THAP domain containing 7 isoform 1 [Homo sapiens]          63   2e-10
gi|22749337 THAP domain containing 8 [Homo sapiens]                    62   4e-10
gi|9910354 THAP domain containing 10 [Homo sapiens]                    46   3e-05
gi|194440673 THAP domain containing 5 isoform 2 [Homo sapiens]         45   5e-05
gi|118918407 spectrin repeat containing, nuclear envelope 2 isof...    38   0.006
gi|118918403 spectrin repeat containing, nuclear envelope 2 isof...    38   0.006
gi|40354197 THAP domain containing 11 [Homo sapiens]                   36   0.024
gi|75750474 spectrin domain with coiled-coils 1 NSP5a3b [Homo sa...    31   0.77 
gi|75750468 spectrin domain with coiled-coils 1 NSP5a3a [Homo sa...    31   0.77 
gi|75750472 spectrin domain with coiled-coils 1 NSP5b3b [Homo sa...    31   0.77 
gi|75750466 spectrin domain with coiled-coils 1 NSP5b3a [Homo sa...    31   0.77 
gi|217416398 hyaluronan-mediated motility receptor isoform c [Ho...    31   1.00 
gi|75677576 dyslexia susceptibility 1 candidate 1 isoform c [Hom...    30   1.3  
gi|75677567 dyslexia susceptibility 1 candidate 1 isoform b [Hom...    30   1.3  
gi|75677570 dyslexia susceptibility 1 candidate 1 isoform a [Hom...    30   1.3  
gi|50658061 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member...    30   1.3  
gi|38348344 hypothetical protein LOC374355 [Homo sapiens]              30   1.3  
gi|24308223 hypothetical protein LOC57577 [Homo sapiens]               30   1.3  
gi|215982794 myosin VA isoform 2 [Homo sapiens]                        30   1.7  
gi|215982791 myosin VA isoform 1 [Homo sapiens]                        30   1.7  
gi|45238858 WD repeat domain 44 protein [Homo sapiens]                 30   1.7  

>gi|13899259 THAP domain containing, apoptosis associated protein 2
           [Homo sapiens]
          Length = 228

 Score =  462 bits (1190), Expect = e-131
 Identities = 228/228 (100%), Positives = 228/228 (100%)

Query: 1   MPTNCAAAGCATTYNKHINISFHRFPLDPKRRKEWVRLVRRKNFVPGKHTFLCSKHFEAS 60
           MPTNCAAAGCATTYNKHINISFHRFPLDPKRRKEWVRLVRRKNFVPGKHTFLCSKHFEAS
Sbjct: 1   MPTNCAAAGCATTYNKHINISFHRFPLDPKRRKEWVRLVRRKNFVPGKHTFLCSKHFEAS 60

Query: 61  CFDLTGQTRRLKMDAVPTIFDFCTHIKSMKLKSRNLLKKNNSCSPAGPSNLKSNISSQQV 120
           CFDLTGQTRRLKMDAVPTIFDFCTHIKSMKLKSRNLLKKNNSCSPAGPSNLKSNISSQQV
Sbjct: 61  CFDLTGQTRRLKMDAVPTIFDFCTHIKSMKLKSRNLLKKNNSCSPAGPSNLKSNISSQQV 120

Query: 121 LLEHSYAFRNPMEAKKRIIKLEKEIASLRRKMKTCLQKERRATRRWIKATCLVKNLEANS 180
           LLEHSYAFRNPMEAKKRIIKLEKEIASLRRKMKTCLQKERRATRRWIKATCLVKNLEANS
Sbjct: 121 LLEHSYAFRNPMEAKKRIIKLEKEIASLRRKMKTCLQKERRATRRWIKATCLVKNLEANS 180

Query: 181 VLPKGTSEHMLPTALSSLPLEDFKILEQDQQDKTLLSLNLKQTKSTFI 228
           VLPKGTSEHMLPTALSSLPLEDFKILEQDQQDKTLLSLNLKQTKSTFI
Sbjct: 181 VLPKGTSEHMLPTALSSLPLEDFKILEQDQQDKTLLSLNLKQTKSTFI 228


>gi|8922446 THAP domain containing, apoptosis associated protein 1
           isoform 1 [Homo sapiens]
          Length = 213

 Score =  105 bits (261), Expect = 4e-23
 Identities = 64/180 (35%), Positives = 91/180 (50%), Gaps = 19/180 (10%)

Query: 1   MPTNCAAAGCATTYNKHINISFHRFPLD-PKRRKEWVRLVRRKNFVPGKHTFLCSKHFEA 59
           M  +C+A GC   Y+K   +SFH+FPL  P   KEW   VRRKNF P K++ +CS+HF  
Sbjct: 1   MVQSCSAYGCKNRYDKDKPVSFHKFPLTRPSLCKEWEAAVRRKNFKPTKYSSICSEHFTP 60

Query: 60  SCFDLTGQTRRLKMDAVPTIFDFCTHIKSMKLKSRNLLKKNNSCSPAGPSNLKSNISSQ- 118
            CF      + LK +AVPTIF  CT       K  +LL+      P       S + +  
Sbjct: 61  DCFKRECNNKLLKENAVPTIF-LCTEPHD---KKEDLLEPQEQLPPPPLPPPVSQVDAAI 116

Query: 119 -------------QVLLEHSYAFRNPMEAKKRIIKLEKEIASLRRKMKTCLQKERRATRR 165
                         V  +H+Y   + M  +KRI +LE+++  LR+K+KT  Q+ RR  R+
Sbjct: 117 GLLMPPLQTPVNLSVFCDHNYTVEDTMHQRKRIHQLEQQVEKLRKKLKTAQQRCRRQERQ 176


>gi|42734379 THAP domain containing, apoptosis associated protein 3
           [Homo sapiens]
          Length = 175

 Score = 80.9 bits (198), Expect = 8e-16
 Identities = 40/106 (37%), Positives = 60/106 (56%), Gaps = 2/106 (1%)

Query: 1   MPTNCAAAGCATTYN-KHINISFHRFPLD-PKRRKEWVRLVRRKNFVPGKHTFLCSKHFE 58
           MP +CAA  C   Y+ +   ++FHRFP   P+  KEWV  + R NF P +HT +CS+HF 
Sbjct: 1   MPKSCAARQCCNRYSSRRKQLTFHRFPFSRPELLKEWVLNIGRGNFKPKQHTVICSEHFR 60

Query: 59  ASCFDLTGQTRRLKMDAVPTIFDFCTHIKSMKLKSRNLLKKNNSCS 104
             CF   G  + LK +AVPT+F F    + ++  +    ++ N+ S
Sbjct: 61  PECFSAFGNRKNLKHNAVPTVFAFQDPTQQVRENTDPASERGNASS 106


>gi|94536788 THAP domain containing 9 [Homo sapiens]
          Length = 903

 Score = 74.3 bits (181), Expect = 8e-14
 Identities = 63/224 (28%), Positives = 104/224 (46%), Gaps = 31/224 (13%)

Query: 1   MPTNCAAAGCAT---TYNKHINISFHRFPLDPKRRKEWVRLVRR------KNFVPGKHTF 51
           M  +C+A GC+T     ++   +SFH+FP D  +R +W+R V R      K ++PG    
Sbjct: 1   MTRSCSAVGCSTRDTVLSRERGLSFHQFPTDTIQRSKWIRAVNRVDPRSKKIWIPGPGAI 60

Query: 52  LCSKHFEASCFDLTGQTRRLKMDAVPTIFDF----CTHIKSMKLKSRNLLKKNNSCSPAG 107
           LCSKHF+ S F+  G  R+LK  AVP++  +      H+K    K+R  + K        
Sbjct: 61  LCSKHFQESDFESYGIRRKLKKGAVPSVSLYKIPQGVHLKG---KARQKILKQPL----- 112

Query: 108 PSNLKSNISSQQVLLE-HSYAFRNPMEAKKRIIKLEKEIASLRRKMKTCLQKERRATRRW 166
           P N      SQ+V  E H+Y+ + P+      +   +++  + +K    ++  R   +R 
Sbjct: 113 PDN------SQEVATEDHNYSLKTPLTIGAEKLAEVQQMLQVSKKRLISVKNYRMIKKR- 165

Query: 167 IKATCLVKNLEANSVLPKGTSEHMLPTALSSLPLEDFKILEQDQ 210
            K   L+  L    +L + T E +L    S    E +   E D+
Sbjct: 166 -KGLRLIDALVEEKLLSEET-ECLLRAQFSDFKWELYNWRETDE 207


>gi|21389507 THAP domain containing 6 [Homo sapiens]
          Length = 222

 Score = 72.4 bits (176), Expect = 3e-13
 Identities = 52/200 (26%), Positives = 94/200 (47%), Gaps = 27/200 (13%)

Query: 5   CAAAGCATTY---NKHINISFHRFPLDPKRRKEWVRLVRRKN------FVPGKHTFLCSK 55
           C+A GCA+     +K   ++FH FP D   +++WV  ++R +      + P K   LCS+
Sbjct: 5   CSAIGCASRCLPNSKLKGLTFHVFPTDENIKRKWVLAMKRLDVNAAGIWEPKKGDVLCSR 64

Query: 56  HFEASCFDLTGQTRRLKMDAVPTIFDFCTHIKSMKLKSRNLLKKNNSCSPAGPSNLKSNI 115
           HF+ + FD +    +LK   +P+IFD   H++  + K     +KN +      +N   ++
Sbjct: 65  HFKKTDFDRSAPNIKLKPGVIPSIFDSPYHLQGKREKLH--CRKNFTLKTVPATNYNHHL 122

Query: 116 ---------SSQQVLLEHSYA-FRNPMEAKKRIIKLEKEIASLRRKMKTCLQKER----- 160
                       Q + EHSY+   +P + K ++  +  E+   +  ++  L +E+     
Sbjct: 123 VGASSCIEEFQSQFIFEHSYSVMDSPKKLKHKLDHVIGELEDTKESLRNVLDREKRFQKS 182

Query: 161 -RATRRWIKATCLVKNLEAN 179
            R T R +K  CL+    AN
Sbjct: 183 LRKTIRELKDECLISQETAN 202


>gi|31982895 THAP domain containing 4 [Homo sapiens]
          Length = 577

 Score = 68.2 bits (165), Expect = 6e-12
 Identities = 38/81 (46%), Positives = 49/81 (60%), Gaps = 5/81 (6%)

Query: 5  CAAAGCATTYNKHIN--ISFHRFPL-DPKRRKEWVRLVRRKNFVPGKHTFLCSKHFEASC 61
          CAA  C+    K     +SFHRFPL D KR  +W++ V+R N+ P K++FLCS+HF    
Sbjct: 5  CAAVNCSNRQGKGEKRAVSFHRFPLKDSKRLIQWLKAVQRDNWTPTKYSFLCSEHFTKDS 64

Query: 62 FD--LTGQTRRLKMDAVPTIF 80
          F   L  Q R LK  AVP+IF
Sbjct: 65 FSKRLEDQHRLLKPTAVPSIF 85


>gi|194440668 THAP domain containing 5 isoform 1 [Homo sapiens]
          Length = 395

 Score = 67.8 bits (164), Expect = 7e-12
 Identities = 48/151 (31%), Positives = 69/151 (45%), Gaps = 26/151 (17%)

Query: 1   MPTNCAAAGCATTY---NKHINISFHRFPLDPKRRKE-WVRLVRRKNFVPGKHTFLCSKH 56
           MP  CAA  C       NK   +SF+ FPL  K R E W++ ++R ++VP K+ FLCS H
Sbjct: 1   MPRYCAAICCKNRRGRNNKDRKLSFYPFPLHDKERLEKWLKNMKRDSWVPSKYQFLCSDH 60

Query: 57  FEASCFDLTGQTRRLKMDAVPTIFDFCTHIKSMKLKSRNLLKKNNSCSPAGPSNLKSNIS 116
           F     D+    R LK  AVPTIF              +L + N    P+   + K N+ 
Sbjct: 61  FTPDSLDIRWGIRYLKQTAVPTIF--------------SLPEDNQGKDPSKKKSQKKNLE 106

Query: 117 SQQVLL-----EHSYAFRNPMEAKKRIIKLE 142
            ++ +      E S+      E KK I+  +
Sbjct: 107 DEKEVCPKAKSEESFVLN---ETKKNIVNTD 134


>gi|19923268 protein-kinase, interferon-inducible double stranded
           RNA dependent inhibitor, repressor of (P58 repressor)
           [Homo sapiens]
          Length = 761

 Score = 65.9 bits (159), Expect = 3e-11
 Identities = 39/106 (36%), Positives = 56/106 (52%), Gaps = 8/106 (7%)

Query: 1   MPTNCAAAGCATTYNKHINISFHRFPLDPKRRKEWVRLVRRKNFVP------GKHTFLCS 54
           MP  CAA  C T  +   +++F RFP DP R ++WV   RR +          KH  LC+
Sbjct: 1   MPNFCAAPNC-TRKSTQSDLAFFRFPRDPARCQKWVENCRRADLEDKTPDQLNKHYRLCA 59

Query: 55  KHFEASCFDLTGQTRR-LKMDAVPTIFDFCTHIKSMKLKSRNLLKK 99
           KHFE S    T   R  L+ +A+PTIFD  +H+ +   + R  +K+
Sbjct: 60  KHFETSMICRTSPYRTVLRDNAIPTIFDLTSHLNNPHSRHRKRIKE 105


>gi|56788351 THAP domain containing 7 isoform 2 [Homo sapiens]
          Length = 309

 Score = 62.8 bits (151), Expect = 2e-10
 Identities = 44/124 (35%), Positives = 59/124 (47%), Gaps = 20/124 (16%)

Query: 1   MPTNCAAAGCATTYNKHIN---ISFHRFPL-DPKRRKEWVRLVRRKN-------FVPGKH 49
           MP +C+AAGC T   +      ISFHR P  D  RR  W+   +R +           ++
Sbjct: 1   MPRHCSAAGCCTRDTRETRNRGISFHRLPKKDNPRRGLWLANCQRLDPSGQGLWDPASEY 60

Query: 50  TFLCSKHFEASCFDLTGQT--RRLKMDAVPTIFDFCTHIKSMKLKSRNLLKKNNSCSPAG 107
            + CSKHFE  CF+L G +   RLK  AVPTIF+  +       K R   K      P G
Sbjct: 61  IYFCSKHFEEDCFELVGISGYHRLKEGAVPTIFESFS-------KLRRTTKTKGHSYPPG 113

Query: 108 PSNL 111
           P+ +
Sbjct: 114 PAEV 117


>gi|56788349 THAP domain containing 7 isoform 1 [Homo sapiens]
          Length = 309

 Score = 62.8 bits (151), Expect = 2e-10
 Identities = 44/124 (35%), Positives = 59/124 (47%), Gaps = 20/124 (16%)

Query: 1   MPTNCAAAGCATTYNKHIN---ISFHRFPL-DPKRRKEWVRLVRRKN-------FVPGKH 49
           MP +C+AAGC T   +      ISFHR P  D  RR  W+   +R +           ++
Sbjct: 1   MPRHCSAAGCCTRDTRETRNRGISFHRLPKKDNPRRGLWLANCQRLDPSGQGLWDPASEY 60

Query: 50  TFLCSKHFEASCFDLTGQT--RRLKMDAVPTIFDFCTHIKSMKLKSRNLLKKNNSCSPAG 107
            + CSKHFE  CF+L G +   RLK  AVPTIF+  +       K R   K      P G
Sbjct: 61  IYFCSKHFEEDCFELVGISGYHRLKEGAVPTIFESFS-------KLRRTTKTKGHSYPPG 113

Query: 108 PSNL 111
           P+ +
Sbjct: 114 PAEV 117


>gi|22749337 THAP domain containing 8 [Homo sapiens]
          Length = 274

 Score = 62.0 bits (149), Expect = 4e-10
 Identities = 35/95 (36%), Positives = 52/95 (54%), Gaps = 5/95 (5%)

Query: 1  MPTNCAAAGCATTYNK----HINISFHRFPL-DPKRRKEWVRLVRRKNFVPGKHTFLCSK 55
          MP  C A  C+ T  +    +  +SF++FPL D  R + W++ +  +++VP  H  LCS+
Sbjct: 1  MPKYCRAPNCSNTAGRLGADNRPVSFYKFPLKDGPRLQAWLQHMGCEHWVPSCHQHLCSE 60

Query: 56 HFEASCFDLTGQTRRLKMDAVPTIFDFCTHIKSMK 90
          HF  SCF      R L+ DAVP+IF      KS +
Sbjct: 61 HFTPSCFQWRWGVRYLRPDAVPSIFSRGPPAKSQR 95


>gi|9910354 THAP domain containing 10 [Homo sapiens]
          Length = 257

 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 33/91 (36%), Positives = 41/91 (45%), Gaps = 14/91 (15%)

Query: 1  MPTNCAAAGCATTYNKHINISFHRFPLDPKRRKEWVRLVR--RKNFVPGK-HTFLCSKHF 57
          MP  C AA C  T       S  RFP D   R  W R VR  R ++  G   + +CS HF
Sbjct: 1  MPARCVAAHCGNTTKS--GKSLFRFPKDRAVRLLWDRFVRGCRADWYGGNDRSVICSDHF 58

Query: 58 EASCFDLT---------GQTRRLKMDAVPTI 79
            +CFD++          Q  RL   AVPT+
Sbjct: 59 APACFDVSSVIQKNLRFSQRLRLVAGAVPTL 89


>gi|194440673 THAP domain containing 5 isoform 2 [Homo sapiens]
          Length = 353

 Score = 45.1 bits (105), Expect = 5e-05
 Identities = 31/109 (28%), Positives = 48/109 (44%), Gaps = 22/109 (20%)

Query: 39  VRRKNFVPGKHTFLCSKHFEASCFDLTGQTRRLKMDAVPTIFDFCTHIKSMKLKSRNLLK 98
           ++R ++VP K+ FLCS HF     D+    R LK  AVPTIF              +L +
Sbjct: 1   MKRDSWVPSKYQFLCSDHFTPDSLDIRWGIRYLKQTAVPTIF--------------SLPE 46

Query: 99  KNNSCSPAGPSNLKSNISSQQVLL-----EHSYAFRNPMEAKKRIIKLE 142
            N    P+   + K N+  ++ +      E S+      E KK I+  +
Sbjct: 47  DNQGKDPSKKKSQKKNLEDEKEVCPKAKSEESFVLN---ETKKNIVNTD 92


>gi|118918407 spectrin repeat containing, nuclear envelope 2 isoform 5
            [Homo sapiens]
          Length = 6907

 Score = 38.1 bits (87), Expect = 0.006
 Identities = 32/114 (28%), Positives = 55/114 (48%), Gaps = 2/114 (1%)

Query: 111  LKSNISSQQVLLEHSYAFRNPMEAKKRIIKLEKEIASLRRKMKTCLQKERRATRRWIKAT 170
            L+S ++  Q L E      +P EAK ++    +E+ S    MK   + +     R+++  
Sbjct: 3303 LESTVAHIQDLTEKLGMISSP-EAKLQLQYTLQELVSKNSAMKEAFKAQETEAERYLENY 3361

Query: 171  CLVKNLEANSVLPKGTSEHMLPTALSSLPLEDFKILEQDQQDKTLLSLNLKQTK 224
               + +E +        E +L  ++SSLPL   + LE+ +Q K L+S NL  TK
Sbjct: 3362 KCYRKMEEDIYTNLSKMETVLGQSMSSLPLSYREALERLEQSKALVS-NLISTK 3414


>gi|118918403 spectrin repeat containing, nuclear envelope 2 isoform 1
            [Homo sapiens]
          Length = 6885

 Score = 38.1 bits (87), Expect = 0.006
 Identities = 32/114 (28%), Positives = 55/114 (48%), Gaps = 2/114 (1%)

Query: 111  LKSNISSQQVLLEHSYAFRNPMEAKKRIIKLEKEIASLRRKMKTCLQKERRATRRWIKAT 170
            L+S ++  Q L E      +P EAK ++    +E+ S    MK   + +     R+++  
Sbjct: 3303 LESTVAHIQDLTEKLGMISSP-EAKLQLQYTLQELVSKNSAMKEAFKAQETEAERYLENY 3361

Query: 171  CLVKNLEANSVLPKGTSEHMLPTALSSLPLEDFKILEQDQQDKTLLSLNLKQTK 224
               + +E +        E +L  ++SSLPL   + LE+ +Q K L+S NL  TK
Sbjct: 3362 KCYRKMEEDIYTNLSKMETVLGQSMSSLPLSYREALERLEQSKALVS-NLISTK 3414


>gi|40354197 THAP domain containing 11 [Homo sapiens]
          Length = 314

 Score = 36.2 bits (82), Expect = 0.024
 Identities = 24/83 (28%), Positives = 34/83 (40%), Gaps = 15/83 (18%)

Query: 5  CAAAGCATTYNKHINISFHRFPLDPKRRKEWVRLVRR-------KNFVPGKHTFLCSKHF 57
          C   GC    ++   + F+ FP D + R+ W++ V R         F P     LCS HF
Sbjct: 6  CCVPGCYNNSHRDKALHFYTFPKDAELRRLWLKNVSRAGVSGCFSTFQPTTGHRLCSVHF 65

Query: 58 EASCFDLTGQTRRLKMDAVPTIF 80
          +          R+     VPTIF
Sbjct: 66 QGG--------RKTYTVRVPTIF 80


>gi|75750474 spectrin domain with coiled-coils 1 NSP5a3b [Homo
           sapiens]
          Length = 987

 Score = 31.2 bits (69), Expect = 0.77
 Identities = 22/91 (24%), Positives = 43/91 (47%), Gaps = 5/91 (5%)

Query: 81  DFCTHIKSMKLKSRNLLKKNNSCSPAGPSNLKSNISSQQVLLEHSYAFR---NPM--EAK 135
           + C H      ++   L++  S S A   ++K  I   +  +E   A +   N +  E +
Sbjct: 550 EICDHQAEQLSRTSLKLQEKASESDAEIKDMKETIFELEDQVEQHRAVKLHNNQLISELE 609

Query: 136 KRIIKLEKEIASLRRKMKTCLQKERRATRRW 166
             +IKLE++ + L R++KT  ++ +  T  W
Sbjct: 610 SSVIKLEEQKSDLERQLKTLTKQMKEETEEW 640


>gi|75750468 spectrin domain with coiled-coils 1 NSP5a3a [Homo
           sapiens]
          Length = 709

 Score = 31.2 bits (69), Expect = 0.77
 Identities = 22/91 (24%), Positives = 43/91 (47%), Gaps = 5/91 (5%)

Query: 81  DFCTHIKSMKLKSRNLLKKNNSCSPAGPSNLKSNISSQQVLLEHSYAFR---NPM--EAK 135
           + C H      ++   L++  S S A   ++K  I   +  +E   A +   N +  E +
Sbjct: 550 EICDHQAEQLSRTSLKLQEKASESDAEIKDMKETIFELEDQVEQHRAVKLHNNQLISELE 609

Query: 136 KRIIKLEKEIASLRRKMKTCLQKERRATRRW 166
             +IKLE++ + L R++KT  ++ +  T  W
Sbjct: 610 SSVIKLEEQKSDLERQLKTLTKQMKEETEEW 640


>gi|75750472 spectrin domain with coiled-coils 1 NSP5b3b [Homo
           sapiens]
          Length = 1068

 Score = 31.2 bits (69), Expect = 0.77
 Identities = 22/91 (24%), Positives = 43/91 (47%), Gaps = 5/91 (5%)

Query: 81  DFCTHIKSMKLKSRNLLKKNNSCSPAGPSNLKSNISSQQVLLEHSYAFR---NPM--EAK 135
           + C H      ++   L++  S S A   ++K  I   +  +E   A +   N +  E +
Sbjct: 631 EICDHQAEQLSRTSLKLQEKASESDAEIKDMKETIFELEDQVEQHRAVKLHNNQLISELE 690

Query: 136 KRIIKLEKEIASLRRKMKTCLQKERRATRRW 166
             +IKLE++ + L R++KT  ++ +  T  W
Sbjct: 691 SSVIKLEEQKSDLERQLKTLTKQMKEETEEW 721


>gi|75750466 spectrin domain with coiled-coils 1 NSP5b3a [Homo
           sapiens]
          Length = 790

 Score = 31.2 bits (69), Expect = 0.77
 Identities = 22/91 (24%), Positives = 43/91 (47%), Gaps = 5/91 (5%)

Query: 81  DFCTHIKSMKLKSRNLLKKNNSCSPAGPSNLKSNISSQQVLLEHSYAFR---NPM--EAK 135
           + C H      ++   L++  S S A   ++K  I   +  +E   A +   N +  E +
Sbjct: 631 EICDHQAEQLSRTSLKLQEKASESDAEIKDMKETIFELEDQVEQHRAVKLHNNQLISELE 690

Query: 136 KRIIKLEKEIASLRRKMKTCLQKERRATRRW 166
             +IKLE++ + L R++KT  ++ +  T  W
Sbjct: 691 SSVIKLEEQKSDLERQLKTLTKQMKEETEEW 721


>gi|217416398 hyaluronan-mediated motility receptor isoform c [Homo
           sapiens]
          Length = 709

 Score = 30.8 bits (68), Expect = 1.00
 Identities = 32/130 (24%), Positives = 51/130 (39%), Gaps = 7/130 (5%)

Query: 77  PTIFDFCTHIKSMKLKSRNLLKKNNSCSPAGPSNLKSNISSQQVLLEHSYAFRNPMEAKK 136
           P  F      K  K   +NL    ++  PA    +KS+ S  +VLL+   A        +
Sbjct: 35  PVSFQKSQRFKQQKESKQNLNVDKDTTLPASARKVKSSESKIRVLLQERGA------QDR 88

Query: 137 RIIKLEKEIASLRRKMKTCL-QKERRATRRWIKATCLVKNLEANSVLPKGTSEHMLPTAL 195
           RI  LE E+  +  ++   L +K   +         L++    N +L    SE+     L
Sbjct: 89  RIQDLETELEKMEARLNAALREKTSLSANNATLEKQLIELTRTNELLKSKFSENGNQKNL 148

Query: 196 SSLPLEDFKI 205
             L LE  K+
Sbjct: 149 RILSLELMKL 158


>gi|75677576 dyslexia susceptibility 1 candidate 1 isoform c [Homo
           sapiens]
          Length = 381

 Score = 30.4 bits (67), Expect = 1.3
 Identities = 18/63 (28%), Positives = 34/63 (53%), Gaps = 1/63 (1%)

Query: 132 MEAKKRIIKLEKEIASLRRKMKTCL-QKERRATRRWIKATCLVKNLEANSVLPKGTSEHM 190
           +EA K   +  +E   ++R+ K C  +K+ +  R+ IK   L +NL + ++ PKG +   
Sbjct: 159 LEAWKEYQRKAEEQKKIQREEKLCQKEKQIKEERKKIKYKSLTRNLASRNLAPKGRNSEN 218

Query: 191 LPT 193
           + T
Sbjct: 219 IFT 221


>gi|75677567 dyslexia susceptibility 1 candidate 1 isoform b [Homo
           sapiens]
          Length = 376

 Score = 30.4 bits (67), Expect = 1.3
 Identities = 18/63 (28%), Positives = 34/63 (53%), Gaps = 1/63 (1%)

Query: 132 MEAKKRIIKLEKEIASLRRKMKTCL-QKERRATRRWIKATCLVKNLEANSVLPKGTSEHM 190
           +EA K   +  +E   ++R+ K C  +K+ +  R+ IK   L +NL + ++ PKG +   
Sbjct: 159 LEAWKEYQRKAEEQKKIQREEKLCQKEKQIKEERKKIKYKSLTRNLASRNLAPKGRNSEN 218

Query: 191 LPT 193
           + T
Sbjct: 219 IFT 221


>gi|75677570 dyslexia susceptibility 1 candidate 1 isoform a [Homo
           sapiens]
          Length = 420

 Score = 30.4 bits (67), Expect = 1.3
 Identities = 18/63 (28%), Positives = 34/63 (53%), Gaps = 1/63 (1%)

Query: 132 MEAKKRIIKLEKEIASLRRKMKTCL-QKERRATRRWIKATCLVKNLEANSVLPKGTSEHM 190
           +EA K   +  +E   ++R+ K C  +K+ +  R+ IK   L +NL + ++ PKG +   
Sbjct: 159 LEAWKEYQRKAEEQKKIQREEKLCQKEKQIKEERKKIKYKSLTRNLASRNLAPKGRNSEN 218

Query: 191 LPT 193
           + T
Sbjct: 219 IFT 221


>gi|50658061 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
            [Homo sapiens]
          Length = 1168

 Score = 30.4 bits (67), Expect = 1.3
 Identities = 35/140 (25%), Positives = 70/140 (50%), Gaps = 15/140 (10%)

Query: 71   LKMDAVPTIFDFCTHIKSMKLKSRNLLKKNNSCSPAGPSNLKSNISSQQV---LLEHSYA 127
            L+ + + TI DF   IKS  L +  L++   + +     ++   + + +V   +L+    
Sbjct: 1014 LQHENLETIVDF---IKST-LPNLGLVQMEKTINQVFEMDIAKQLQAYEVEYHVLQEELI 1069

Query: 128  FRNPMEAKKRIIKLEKEIASLRRKMKTCLQKERRATRRWIKATCLVKNLEANSVLPKGTS 187
              +P+   +R+ KLEK  +SLR++    L++ + A  R       +++LEA ++    +S
Sbjct: 1070 DSSPLSDNQRMDKLEKTNSSLRKQNLDLLEQLQVANGR-------IQSLEA-TIEKLLSS 1121

Query: 188  EHMLPTALSSLPLEDFKILE 207
            E  L  A+ +L LE   +L+
Sbjct: 1122 ESKLKQAMLTLELERSALLQ 1141


>gi|38348344 hypothetical protein LOC374355 [Homo sapiens]
          Length = 258

 Score = 30.4 bits (67), Expect = 1.3
 Identities = 26/106 (24%), Positives = 49/106 (46%), Gaps = 10/106 (9%)

Query: 76  VPTIFDFCTHIKSMKLKSRNLLKKNNSCSPAGPSNLKSNISSQQVLLEHSYAFRNPMEAK 135
           +  I DF    +  K K   L+K+N     +   N  + + S+   +EH  +  N ++ +
Sbjct: 109 IKEITDFNNDYEITK-KRELLMKENVKIEISDLENQANMLKSEMKSMEHDSSQLNELQKQ 167

Query: 136 KRIIKLEKEIASLRRKMKTCLQKERRATRRWIKATCLVKNLEANSV 181
           K   +L +E+ +L+RK+K    +E        ++ C  K LEA  +
Sbjct: 168 KS--ELIQELFTLQRKLKVFEDEEN-------ESICTTKYLEAEKI 204


>gi|24308223 hypothetical protein LOC57577 [Homo sapiens]
          Length = 936

 Score = 30.4 bits (67), Expect = 1.3
 Identities = 28/98 (28%), Positives = 51/98 (52%), Gaps = 13/98 (13%)

Query: 129 RNPMEAKKRIIKLEKEIASLRRKMKTCLQKERRATRRWIKATCLV--KNLEANSVLPKGT 186
           R  +EAKK   ++++E+  LRR++      ERR T   +KA   +  K  E NS   + +
Sbjct: 237 RKALEAKKEEEEIQREMVKLRREI-----IERRRT---VKAAWKIEKKRQEENS---QNS 285

Query: 187 SEHMLPTALSSLPLEDFKILEQDQQDKTLLSLNLKQTK 224
           SE ++  +   LP E+  + E+ ++ K +L    K+ +
Sbjct: 286 SEKVMFQSTHILPDEEKMVKERKRKLKEVLIQTFKENQ 323


>gi|215982794 myosin VA isoform 2 [Homo sapiens]
          Length = 1828

 Score = 30.0 bits (66), Expect = 1.7
 Identities = 30/103 (29%), Positives = 44/103 (42%), Gaps = 18/103 (17%)

Query: 134  AKKRIIKLEKEIASLR------RKMKTCLQKERRATRRWIKATCLVKNLEANSVLPKGTS 187
            A  R++ L++EIA LR      R  K C+  E  A R   +   LV NL+  + L K   
Sbjct: 981  ATGRVLSLQEEIAKLRKDLEQTRSEKKCI--EEHADRYKQETEQLVSNLKEENTLLKQEK 1038

Query: 188  EHM----------LPTALSSLPLEDFKILEQDQQDKTLLSLNL 220
            E +          +   +    +E+ K LE D  D+ L   NL
Sbjct: 1039 EALNHRIVQQAKEMTETMEKKLVEETKQLELDLNDERLRYQNL 1081


>gi|215982791 myosin VA isoform 1 [Homo sapiens]
          Length = 1855

 Score = 30.0 bits (66), Expect = 1.7
 Identities = 30/103 (29%), Positives = 44/103 (42%), Gaps = 18/103 (17%)

Query: 134  AKKRIIKLEKEIASLR------RKMKTCLQKERRATRRWIKATCLVKNLEANSVLPKGTS 187
            A  R++ L++EIA LR      R  K C+  E  A R   +   LV NL+  + L K   
Sbjct: 981  ATGRVLSLQEEIAKLRKDLEQTRSEKKCI--EEHADRYKQETEQLVSNLKEENTLLKQEK 1038

Query: 188  EHM----------LPTALSSLPLEDFKILEQDQQDKTLLSLNL 220
            E +          +   +    +E+ K LE D  D+ L   NL
Sbjct: 1039 EALNHRIVQQAKEMTETMEKKLVEETKQLELDLNDERLRYQNL 1081


>gi|45238858 WD repeat domain 44 protein [Homo sapiens]
          Length = 913

 Score = 30.0 bits (66), Expect = 1.7
 Identities = 14/41 (34%), Positives = 22/41 (53%)

Query: 160 RRATRRWIKATCLVKNLEANSVLPKGTSEHMLPTALSSLPL 200
           R  T   I A+ ++KNL+    +P   +E  LPT ++ L L
Sbjct: 346 RELTDEEILASVMIKNLDTGEEIPLSLAEEKLPTGINPLTL 386


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.131    0.390 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,489,143
Number of Sequences: 37866
Number of extensions: 341682
Number of successful extensions: 1300
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 23
Number of HSP's that attempted gapping in prelim test: 1257
Number of HSP's gapped (non-prelim): 50
length of query: 228
length of database: 18,247,518
effective HSP length: 99
effective length of query: 129
effective length of database: 14,498,784
effective search space: 1870343136
effective search space used: 1870343136
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.