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Search of human proteins with 68800430
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|68800430 HCLS1 binding protein 3 [Homo sapiens]
(392 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|68800430 HCLS1 binding protein 3 [Homo sapiens] 776 0.0
gi|23111032 sorting nexin 1 isoform b [Homo sapiens] 55 1e-07
gi|23111036 sorting nexin 1 isoform c [Homo sapiens] 53 4e-07
gi|23111034 sorting nexin 1 isoform a [Homo sapiens] 53 4e-07
gi|23111038 sorting nexin 2 [Homo sapiens] 48 1e-05
gi|210032580 SET domain containing 1B [Homo sapiens] 45 9e-05
gi|110349719 titin isoform N2-A [Homo sapiens] 40 0.003
gi|31563383 serum/glucocorticoid regulated kinase 3 isoform 2 [H... 40 0.003
gi|31563382 serum/glucocorticoid regulated kinase 3 isoform 1 [H... 40 0.003
gi|75813626 serum/glucocorticoid regulated kinase 3 isoform 1 [H... 40 0.003
gi|116256464 hypothetical protein LOC343990 [Homo sapiens] 40 0.004
gi|237757326 synaptojanin 1 isoform d [Homo sapiens] 39 0.006
gi|187607445 hypothetical protein LOC79137 [Homo sapiens] 39 0.006
gi|90903231 huntingtin [Homo sapiens] 39 0.008
gi|67188445 CTD (carboxy-terminal domain, RNA polymerase II, pol... 39 0.011
gi|239787762 SH2 domain protein 2A isoform 4 [Homo sapiens] 38 0.014
gi|239787758 SH2 domain protein 2A isoform 3 [Homo sapiens] 38 0.014
gi|239787752 SH2 domain protein 2A isoform 1 [Homo sapiens] 38 0.014
gi|239787750 SH2 domain protein 2A isoform 2 [Homo sapiens] 38 0.014
gi|239787783 SH2 domain protein 2A isoform 2 [Homo sapiens] 38 0.014
gi|46370089 sorting nexin 15 isoform B [Homo sapiens] 38 0.018
gi|22547191 sorting nexin 15 isoform A [Homo sapiens] 38 0.018
gi|63054866 leucine rich repeat containing 16A [Homo sapiens] 37 0.024
gi|78042577 MAP7 domain containing 1 [Homo sapiens] 37 0.024
gi|56549666 tyrosine kinase, non-receptor, 2 isoform 1 [Homo sap... 37 0.040
gi|58331191 tyrosine kinase, non-receptor, 2 isoform 2 [Homo sap... 37 0.040
gi|153792074 proline rich 12 [Homo sapiens] 37 0.040
gi|237757312 synaptojanin 1 isoform c [Homo sapiens] 36 0.052
gi|237757310 synaptojanin 1 isoform a [Homo sapiens] 36 0.052
gi|237757308 synaptojanin 1 isoform b [Homo sapiens] 36 0.052
>gi|68800430 HCLS1 binding protein 3 [Homo sapiens]
Length = 392
Score = 776 bits (2005), Expect = 0.0
Identities = 392/392 (100%), Positives = 392/392 (100%)
Query: 1 MQSPAVLVTSRRLQNAHTGLDLTVPQHQEVRGKMMSGHVEYQILVVTRLAAFKSAKHRPE 60
MQSPAVLVTSRRLQNAHTGLDLTVPQHQEVRGKMMSGHVEYQILVVTRLAAFKSAKHRPE
Sbjct: 1 MQSPAVLVTSRRLQNAHTGLDLTVPQHQEVRGKMMSGHVEYQILVVTRLAAFKSAKHRPE 60
Query: 61 DVVQFLVSKKYSEIEEFYQKLSSRYAAASLPPLPRKVLFVGESDIRERRAVFNEILRCVS 120
DVVQFLVSKKYSEIEEFYQKLSSRYAAASLPPLPRKVLFVGESDIRERRAVFNEILRCVS
Sbjct: 61 DVVQFLVSKKYSEIEEFYQKLSSRYAAASLPPLPRKVLFVGESDIRERRAVFNEILRCVS 120
Query: 121 KDAELAGSPELLEFLGTRSPGAAGLTSRDSSVLDGTDSQTGNDEEAFDFFEEQDQVAEEG 180
KDAELAGSPELLEFLGTRSPGAAGLTSRDSSVLDGTDSQTGNDEEAFDFFEEQDQVAEEG
Sbjct: 121 KDAELAGSPELLEFLGTRSPGAAGLTSRDSSVLDGTDSQTGNDEEAFDFFEEQDQVAEEG 180
Query: 181 PPVQSLKGEDAEESLEEEEALDPLGIMRSKKPKKHPKVAVKAKPSPRLTIFDEEVDPDEG 240
PPVQSLKGEDAEESLEEEEALDPLGIMRSKKPKKHPKVAVKAKPSPRLTIFDEEVDPDEG
Sbjct: 181 PPVQSLKGEDAEESLEEEEALDPLGIMRSKKPKKHPKVAVKAKPSPRLTIFDEEVDPDEG 240
Query: 241 LFGPGRKLSPQDPSEDVSSVDPLKLFDDPDLGGAIPLGDSLLLPAACESGGPTPSLSHRD 300
LFGPGRKLSPQDPSEDVSSVDPLKLFDDPDLGGAIPLGDSLLLPAACESGGPTPSLSHRD
Sbjct: 241 LFGPGRKLSPQDPSEDVSSVDPLKLFDDPDLGGAIPLGDSLLLPAACESGGPTPSLSHRD 300
Query: 301 ASKELFRVEEDLDQILNLGAEPKPKPQLKPKPPVAAKPVIPRKPAVPPKAGPAEAVAGQQ 360
ASKELFRVEEDLDQILNLGAEPKPKPQLKPKPPVAAKPVIPRKPAVPPKAGPAEAVAGQQ
Sbjct: 301 ASKELFRVEEDLDQILNLGAEPKPKPQLKPKPPVAAKPVIPRKPAVPPKAGPAEAVAGQQ 360
Query: 361 KPQEQIQAMDEMDILQYIQDHDTPAQAAPSLF 392
KPQEQIQAMDEMDILQYIQDHDTPAQAAPSLF
Sbjct: 361 KPQEQIQAMDEMDILQYIQDHDTPAQAAPSLF 392
>gi|23111032 sorting nexin 1 isoform b [Homo sapiens]
Length = 457
Score = 55.1 bits (131), Expect = 1e-07
Identities = 52/204 (25%), Positives = 85/204 (41%), Gaps = 35/204 (17%)
Query: 2 QSPAVLVTSRRLQNAHTGLDLTVPQHQEVR----GKMMSGHVEYQILVVTRLAAFKSAKH 57
QSP + + + N + Q QE + G M+ +V Y++ T L F+S
Sbjct: 57 QSPKITTSLLPINNGSKENGIHEEQDQEPQDLFAGDGMNAYVAYKVTTQTSLPLFRSK-- 114
Query: 58 RPEDVVQFLVSKKYSEIEEFYQKLSSRYAAAS--LPPLPRKVLF------VGESD----- 104
QF V +++S+ Y+KLS +++ +PP P K L VG+ D
Sbjct: 115 ------QFAVKRRFSDFLGLYEKLSEKHSQNGFIVPPPPEKSLIGMTKVKVGKEDSSSAE 168
Query: 105 -IRERRAVFNEILRCVSKDAELAGSPELLEFL---------GTRSPGAAGLTSRDSSVLD 154
+ +RRA L+ + + P++ EFL GT++ AGL + D
Sbjct: 169 FLEKRRAALERYLQRIVNHPTMLQDPDVREFLEKEELPRAVGTQTLSGAGLLKMFNKATD 228
Query: 155 GTDSQTGNDEEAFDFFEEQDQVAE 178
T E+ +FEE+ Q E
Sbjct: 229 AVSKMTIKMNESDIWFEEKLQEVE 252
>gi|23111036 sorting nexin 1 isoform c [Homo sapiens]
Length = 474
Score = 53.1 bits (126), Expect = 4e-07
Identities = 50/182 (27%), Positives = 78/182 (42%), Gaps = 32/182 (17%)
Query: 21 DLTVP-QHQEVRGKMMSGHVEYQILVVTRLAAFKSAKHRPEDVVQFLVSKKYSEIEEFYQ 79
DLTV E G M+ +V Y++ T L F+S QF V +++S+ Y+
Sbjct: 144 DLTVGITDPEKIGDGMNAYVAYKVTTQTSLPLFRSK--------QFAVKRRFSDFLGLYE 195
Query: 80 KLSSRYAAAS--LPPLPRKVLF------VGESD------IRERRAVFNEILRCVSKDAEL 125
KLS +++ +PP P K L VG+ D + +RRA L+ + +
Sbjct: 196 KLSEKHSQNGFIVPPPPEKSLIGMTKVKVGKEDSSSAEFLEKRRAALERYLQRIVNHPTM 255
Query: 126 AGSPELLEFL---------GTRSPGAAGLTSRDSSVLDGTDSQTGNDEEAFDFFEEQDQV 176
P++ EFL GT++ AGL + D T E+ +FEE+ Q
Sbjct: 256 LQDPDVREFLEKEELPRAVGTQTLSGAGLLKMFNKATDAVSKMTIKMNESDIWFEEKLQE 315
Query: 177 AE 178
E
Sbjct: 316 VE 317
>gi|23111034 sorting nexin 1 isoform a [Homo sapiens]
Length = 522
Score = 53.1 bits (126), Expect = 4e-07
Identities = 50/182 (27%), Positives = 78/182 (42%), Gaps = 32/182 (17%)
Query: 21 DLTVP-QHQEVRGKMMSGHVEYQILVVTRLAAFKSAKHRPEDVVQFLVSKKYSEIEEFYQ 79
DLTV E G M+ +V Y++ T L F+S QF V +++S+ Y+
Sbjct: 144 DLTVGITDPEKIGDGMNAYVAYKVTTQTSLPLFRSK--------QFAVKRRFSDFLGLYE 195
Query: 80 KLSSRYAAAS--LPPLPRKVLF------VGESD------IRERRAVFNEILRCVSKDAEL 125
KLS +++ +PP P K L VG+ D + +RRA L+ + +
Sbjct: 196 KLSEKHSQNGFIVPPPPEKSLIGMTKVKVGKEDSSSAEFLEKRRAALERYLQRIVNHPTM 255
Query: 126 AGSPELLEFL---------GTRSPGAAGLTSRDSSVLDGTDSQTGNDEEAFDFFEEQDQV 176
P++ EFL GT++ AGL + D T E+ +FEE+ Q
Sbjct: 256 LQDPDVREFLEKEELPRAVGTQTLSGAGLLKMFNKATDAVSKMTIKMNESDIWFEEKLQE 315
Query: 177 AE 178
E
Sbjct: 316 VE 317
>gi|23111038 sorting nexin 2 [Homo sapiens]
Length = 519
Score = 48.1 bits (113), Expect = 1e-05
Identities = 48/206 (23%), Positives = 88/206 (42%), Gaps = 37/206 (17%)
Query: 1 MQSPAVLVTSRR-LQNAHTG----LDLTVPQHQEVRGKMMSGHVEYQILVVTRLAAFKSA 55
M +P + SR ++ G +++ V ++V G M+ ++ Y++ T L+ F +
Sbjct: 118 MSAPVIFDRSREEIEEEANGDIFDIEIGVSDPEKV-GDGMNAYMAYRVTTKTSLSMFSKS 176
Query: 56 KHRPEDVVQFLVSKKYSEIEEFYQKLSSRYAAAS--LPPLPRKVLF------VGESD--- 104
+F V +++S+ + KL+S+Y +PP P K + VG+ D
Sbjct: 177 --------EFSVKRRFSDFLGLHSKLASKYLHVGYIVPPAPEKSIVGMTKVKVGKEDSSS 228
Query: 105 ---IRERRAVFNEILRCVSKDAELAGSPELLEFL---------GTRSPGAAGLTSRDSSV 152
+ +RRA L+ K L P+L +FL T++ AG+ +
Sbjct: 229 TEFVEKRRAALERYLQRTVKHPTLLQDPDLRQFLESSELPRAVNTQALSGAGILRMVNKA 288
Query: 153 LDGTDSQTGNDEEAFDFFEEQDQVAE 178
D + T E+ +FEE+ Q E
Sbjct: 289 ADAVNKMTIKMNESDAWFEEKQQQFE 314
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 45.4 bits (106), Expect = 9e-05
Identities = 57/239 (23%), Positives = 91/239 (38%), Gaps = 27/239 (11%)
Query: 121 KDAELAGSPELLEFLGTRSPGAAGLTSRDSSVLDGTDSQTGNDEEAFDFFEEQDQVAEEG 180
KD + E + + +++ + S +SS + + + + E +E++ VA E
Sbjct: 1089 KDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSE-----DEEEVVARE- 1142
Query: 181 PPVQSLKGEDAEESLEEEEALDPLGIMRSKKPKKHPKVAVKAKPSPRLTIFD-----EEV 235
EE EEEE + M S P+ + +A +P D EEV
Sbjct: 1143 -----------EEEEEEEEEMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEV 1191
Query: 236 DPDEGLFGPGRKLSPQD-PSEDVSSVDPLKLFDDPDLGGAIPLGDSLLLPAA-CESGGPT 293
D + P + S D P V +P + P+ G G LL P +
Sbjct: 1192 DIETEAVAPEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEAR 1251
Query: 294 PSLSHRDASKELFRVEEDLDQILNLGAEPK---PKPQLKPKPPVAAKPVIPRKPAVPPK 349
P LS A + VE + +L L +P P+P P PP + P+VPP+
Sbjct: 1252 PPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPE 1310
Score = 30.0 bits (66), Expect = 3.8
Identities = 14/35 (40%), Positives = 16/35 (45%)
Query: 322 PKPKPQLKPKPPVAAKPVIPRKPAVPPKAGPAEAV 356
P P P P+P P +P P PP A PA V
Sbjct: 691 PPPPPPPPPQPGFPMPPPLPPPPPPPPPAHPAVTV 725
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 40.4 bits (93), Expect = 0.003
Identities = 47/192 (24%), Positives = 76/192 (39%), Gaps = 18/192 (9%)
Query: 168 DFFEEQDQVAEEGPPVQSLKGEDAEESLEEEEALDPLGIMRSKKP---KKHPKVAVKAKP 224
+ FEE ++VA E PP + ++ E E A P + KKP KK P V K
Sbjct: 10664 EVFEEPEEVALEEPPAEVVE--------EPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPE 10715
Query: 225 SPRLTIFD--EEVDPDEGLFGPGRKLSPQDPSEDVSSVDPLKLFDDPDLGGAIPLGDSLL 282
P + + + +EV P++ + + P+ P + V + P+ A+P +
Sbjct: 10716 LPPVKVPEVPKEVVPEKKV----PLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVP 10771
Query: 283 LPAACESGGPTPSLSHRDASKELFRVEEDLDQILNLGAEPKPKPQLKPKPPVAAKPVIPR 342
PA P L + A R E ++ E P+ ++ P+
Sbjct: 10772 -PAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEE 10830
Query: 343 KPAVPPKAGPAE 354
+P VPP A P E
Sbjct: 10831 EPEVPPPAVPEE 10842
Score = 37.4 bits (85), Expect = 0.024
Identities = 54/230 (23%), Positives = 88/230 (38%), Gaps = 36/230 (15%)
Query: 149 DSSVLDGTDSQTGNDEEAFDFFEEQDQVAEEGPPVQSLKGEDAEESLEEEEALD------ 202
+ VL + +EE EE EE PP + E+ EE + EEE L
Sbjct: 10123 EEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEE-EEFVPEEEVLPEVKPKV 10181
Query: 203 --PLGIMRSKK----------------PKKHPKVAVKAKPSPRLTIFDEEVDPDEGLFGP 244
P + KK P K P+V K + + +EEV P E P
Sbjct: 10182 PVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEKRIILPKEEEVLPVEVTEEP 10241
Query: 245 GRK-LSPQDPSEDVSSVDPLKLFDDPDLGGAIPLGDSLLLPAACESGGPTPSLSHRDASK 303
+ +S ++ E+ S++ ++ P + ++ A E+ P P +K
Sbjct: 10242 EEEPISEEEIPEEPPSIEEVEEVAPPRV-------PEVIKKAVPEAPTPVPKKVEAPPAK 10294
Query: 304 ELFRVEEDLDQI--LNLGAEPKPKPQLKPKPPVAAKPVIPRKPAVPPKAG 351
++ E+ + A P P++ K P K ++P+K AVPP G
Sbjct: 10295 VSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVP-EKKVLVPKKEAVPPAKG 10343
Score = 35.4 bits (80), Expect = 0.089
Identities = 36/144 (25%), Positives = 58/144 (40%), Gaps = 18/144 (12%)
Query: 210 KKPKKHPKVAVK-AKPSPRLTIFDEEVDPDEGLFGPGRKLSPQDPSEDVSSVDPLKLFDD 268
K PKK V V A P +F+EE+ P+E + ++ P++ E+V + L ++
Sbjct: 10087 KVPKKREPVPVPVALPQEEEVLFEEEIVPEEEVLPEEEEVLPEE--EEVLPEEEEVLPEE 10144
Query: 269 PDLGGAIPLGDSLLLPAACESGGPTPSLSHRDASKELFRVEEDLDQILNLGAEPKPKPQL 328
++ E P + +E EE L ++ P P P++
Sbjct: 10145 EEI--------------PPEEEEVPPEEEYVPEEEEFVPEEEVLPEVKPKVPVPAPVPEI 10190
Query: 329 KPKPPVAAKPVIPRKPAVPPKAGP 352
K K K VIP+K PP P
Sbjct: 10191 K-KKVTEKKVVIPKKEEAPPAKVP 10213
Score = 33.1 bits (74), Expect = 0.44
Identities = 43/154 (27%), Positives = 66/154 (42%), Gaps = 25/154 (16%)
Query: 199 EALDPLGIMRSKKPKKHPKVAVKAKPSPRLTIFDEEVDPDEGLFGPGRKLSPQDPSEDVS 258
E L P ++ KK P +A P P++ +EV P++ + P P+ P
Sbjct: 10497 EVLPPKEVVPEKKVPVPPAKKPEAPP-PKVPEAPKEVVPEKKVPVP----PPKKPE---- 10547
Query: 259 SVDPLKLFDDPDLGGAIPLGDSLLLPAACESGGPTPSLSHRDASKELFRVEEDLDQILNL 318
V P K+ + P A+P +P A +P +A KE+ ++ +
Sbjct: 10548 -VPPTKVPEVPK--AAVP---EKKVPEAIPPKPESPPPEVPEAPKEVVPEKK-------V 10594
Query: 319 GAEPKPKPQLKP-KPPVAAKPVIPRK--PAVPPK 349
A P KP++ P K P A K V+P K P PPK
Sbjct: 10595 PAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPK 10628
Score = 32.7 bits (73), Expect = 0.58
Identities = 50/207 (24%), Positives = 83/207 (40%), Gaps = 25/207 (12%)
Query: 164 EEAFDFFEEQDQVAEEGPPVQSLKGEDAEESLEEEEALDPLGIMRSKKPK-----KHPKV 218
EE +D EE+ + A + V ++ E EES E + P + K P K P +
Sbjct: 9130 EEGYDEGEEEWEEAYQEREVIQVQKEVYEESHERKV---PAKVPEKKAPPPPKVIKKPVI 9186
Query: 219 AVKAKPSPRLTIFDEEVDPDEGLFGPGRKLSPQDPSEDVSSVDPLKLFDDPDLGGAIPLG 278
K S R+ +EE + +K+ PQ PS + +++ + +
Sbjct: 9187 EKIEKTSRRM---EEEKVQVTKVPEVSKKIVPQKPSRTPVQEEVIEVKVPAVHTKKMVIS 9243
Query: 279 DSLLLPAACESGGPTPSLSHRDASKELFRVEEDLDQILNLGAEPKPK-PQLKPKP----- 332
+ + A+ S++ + KE+ EE + ++ EP PK P+L KP
Sbjct: 9244 EEKMFFASHTE--EEVSVTVPEVQKEIV-TEEKIHVAISKRVEPPPKVPELPEKPAPEEV 9300
Query: 333 -----PVAAKPVIPRKPAVPPKAGPAE 354
P +P P+ P VP K P E
Sbjct: 9301 APVPIPKKVEPPAPKVPEVPKKPVPEE 9327
Score = 32.3 bits (72), Expect = 0.76
Identities = 49/188 (26%), Positives = 74/188 (39%), Gaps = 37/188 (19%)
Query: 181 PPVQSLKGEDAEESLEEEEALDPLGIMRSKKPKKHPKVAVKAKPSPRLTIFDEEVDPDEG 240
PP + ED +E + + +A I + K P+K P+V K + +P L + E +
Sbjct: 10883 PPPPAPPKEDVKEKIFQLKA-----IPKKKVPEK-PQVPEKVELTP-LKVPGGEKKVRKL 10935
Query: 241 LFGPGRKLSPQD-----------PSEDVSSVDPLKLFDDPDLGGAIPLGDSLLLPAACES 289
L P RK P++ P E+ V+P KL + + PA E
Sbjct: 10936 L--PERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKL-------------EKVKKPAVPEP 10980
Query: 290 GGPTP--SLSHRDASKELFRVEEDLDQILNLGAEPKPKPQLKPKPPVAAKPVIPRKPAVP 347
P P + +K ++ E A P P P+ KPKP K + P P V
Sbjct: 10981 PPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKPKPEAEVKTIKP--PPVE 11038
Query: 348 PKAGPAEA 355
P+ P A
Sbjct: 11039 PEPTPIAA 11046
Score = 30.0 bits (66), Expect = 3.8
Identities = 20/70 (28%), Positives = 29/70 (41%), Gaps = 1/70 (1%)
Query: 322 PKPKPQLKPKPPVAAKPVIPRKPAVPPKAGPAEAVAGQQKPQEQIQAMDEMDILQYIQDH 381
PK +P PK P K +P + P A EA + P+ Q + E I Q
Sbjct: 9334 PKKEPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPA-KVPEVQKGVVTEEKITIVTQRE 9392
Query: 382 DTPAQAAPSL 391
++P A P +
Sbjct: 9393 ESPPPAVPEI 9402
>gi|31563383 serum/glucocorticoid regulated kinase 3 isoform 2 [Homo
sapiens]
Length = 464
Score = 40.4 bits (93), Expect = 0.003
Identities = 24/80 (30%), Positives = 44/80 (55%), Gaps = 4/80 (5%)
Query: 64 QFLVSKKYSEIEEFYQKLSSRYAAASLPPLPRKVLFVGESD---IRERRAVFNEILRCVS 120
++ V ++Y+E ++ Y L ++ A +L +P K +F D I++RRA NE ++ +
Sbjct: 44 EWFVFRRYAEFDKLYNTLKKQFPAMALK-IPAKRIFGDNFDPDFIKQRRAGLNEFIQNLV 102
Query: 121 KDAELAGSPELLEFLGTRSP 140
+ EL P++ FL SP
Sbjct: 103 RYPELYNHPDVRAFLQMDSP 122
>gi|31563382 serum/glucocorticoid regulated kinase 3 isoform 1 [Homo
sapiens]
Length = 496
Score = 40.4 bits (93), Expect = 0.003
Identities = 24/80 (30%), Positives = 44/80 (55%), Gaps = 4/80 (5%)
Query: 64 QFLVSKKYSEIEEFYQKLSSRYAAASLPPLPRKVLFVGESD---IRERRAVFNEILRCVS 120
++ V ++Y+E ++ Y L ++ A +L +P K +F D I++RRA NE ++ +
Sbjct: 44 EWFVFRRYAEFDKLYNTLKKQFPAMALK-IPAKRIFGDNFDPDFIKQRRAGLNEFIQNLV 102
Query: 121 KDAELAGSPELLEFLGTRSP 140
+ EL P++ FL SP
Sbjct: 103 RYPELYNHPDVRAFLQMDSP 122
>gi|75813626 serum/glucocorticoid regulated kinase 3 isoform 1 [Homo
sapiens]
Length = 496
Score = 40.4 bits (93), Expect = 0.003
Identities = 24/80 (30%), Positives = 44/80 (55%), Gaps = 4/80 (5%)
Query: 64 QFLVSKKYSEIEEFYQKLSSRYAAASLPPLPRKVLFVGESD---IRERRAVFNEILRCVS 120
++ V ++Y+E ++ Y L ++ A +L +P K +F D I++RRA NE ++ +
Sbjct: 44 EWFVFRRYAEFDKLYNTLKKQFPAMALK-IPAKRIFGDNFDPDFIKQRRAGLNEFIQNLV 102
Query: 121 KDAELAGSPELLEFLGTRSP 140
+ EL P++ FL SP
Sbjct: 103 RYPELYNHPDVRAFLQMDSP 122
>gi|116256464 hypothetical protein LOC343990 [Homo sapiens]
Length = 962
Score = 40.0 bits (92), Expect = 0.004
Identities = 47/199 (23%), Positives = 83/199 (41%), Gaps = 38/199 (19%)
Query: 222 AKPSPRLTIFDEEVDPDEGLFGP-GRKLSPQDPSEDVSSVDPLKLFDDPDLGGAIPLGDS 280
AKP PR D + P G + SPQ+ + + +P +P P D
Sbjct: 625 AKPGPRKLAERGPQDSGDRAASPAGPRKSPQEAAAAPGTREPCPAAQEP-----APSEDR 679
Query: 281 LLLPAACESGGPTPSLSHRD-ASKEL---------FRVEEDL-----DQILNLGAEP--- 322
P S + SL +RD AS+E+ R+E L ++ LG P
Sbjct: 680 NPFPVKLRS--TSLSLKYRDGASQEVKGVKRYSAEVRLERSLTVLPKEEKCPLGTAPALR 737
Query: 323 -------KPKPQLKPKPPVAAKPVIPRKP-----AVPPKAGPAEAVAGQQKPQEQIQAMD 370
+ K + +P P+++KP +PRKP +P + P +A G+++P+++ + +
Sbjct: 738 GTRAPSDQGKGKARPPEPLSSKPPLPRKPLLQSFTLPHQPAPPDAGPGEREPRKEPRTAE 797
Query: 371 EMDILQYIQDHDTPAQAAP 389
+ + + + PA P
Sbjct: 798 KRPLRRGAEKSLPPAATGP 816
Score = 29.3 bits (64), Expect = 6.4
Identities = 45/202 (22%), Positives = 68/202 (33%), Gaps = 24/202 (11%)
Query: 172 EQDQVAEEGP------PVQSLKGEDAEES-LEEEEALDPL---GIMRSKKPKKHPKVAVK 221
+QD + GP P+ G A + L+ AL G + + P P
Sbjct: 282 QQDVAPDRGPEPGPPAPLPPPGGARARRARLQHSSALTASVEEGGVPGEDPSSRPATPEL 341
Query: 222 AKPSPRLTIFDEEVDPDEGLFGPGRKLSPQDPSEDVSSVDPLKLFDDPDLGGAIPLGDSL 281
A+P T+ E P EG PG QD E + D + P +
Sbjct: 342 AEPESAPTLRVEPPSPPEGPPNPGPDGGKQD-GEAPPAGPCAPATDKAEEVVCAPEDVAS 400
Query: 282 LLPAACESGGPTPSLSHRDASKELFRVEEDLDQILNLGAEPKPKPQLKPKPPVAAKPVIP 341
P A G TP + A+ E + ++ + AEP P PV+P
Sbjct: 401 PFPTAIPEGDTTPPETDPAATSEAPSARDGPERSVPKEAEPTP-------------PVLP 447
Query: 342 RKPAVPPKAGPAEAVAGQQKPQ 363
+ PP P + +P+
Sbjct: 448 DEEKGPPGPAPEPEREAETEPE 469
>gi|237757326 synaptojanin 1 isoform d [Homo sapiens]
Length = 1526
Score = 39.3 bits (90), Expect = 0.006
Identities = 52/189 (27%), Positives = 70/189 (37%), Gaps = 27/189 (14%)
Query: 185 SLKGEDAEESLEEEEALDPLGIMRSKKPKKHPKVAVKAKPSPRLTIFDEEVDPDEGLFGP 244
+LK D ++LEEE +L+ + I A+ + S L D EV D + G
Sbjct: 962 ALKSPDWIKNLEEEMSLEKISI------------ALPSSTSSTLLGEDAEVAADFDMEG- 1008
Query: 245 GRKLSPQDPSEDVSSVDPLKLFDDPDLG-GAIPLGDSLLLPAACE--SGGPTPSLSHRDA 301
D S +V + P L G G P P S GP PSL R +
Sbjct: 1009 ----DVDDYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPS 1064
Query: 302 SKELFRVEEDLDQILNLGAEPK-PKPQ------LKPKPPVAAKPVIPRKPAVPPKAGPAE 354
Q + A+P P PQ L+PK P +PV P PP+ P
Sbjct: 1065 RAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPP 1124
Query: 355 AVAGQQKPQ 363
+ Q PQ
Sbjct: 1125 SGRSQPSPQ 1133
>gi|187607445 hypothetical protein LOC79137 [Homo sapiens]
Length = 543
Score = 39.3 bits (90), Expect = 0.006
Identities = 68/261 (26%), Positives = 114/261 (43%), Gaps = 28/261 (10%)
Query: 122 DAELAGSPELLEFLGTRSPGA---AGLTSRDSSVLD--GTDSQTGNDEEAFDFFEEQDQV 176
+AELAG +++ T A + L+ ++S+L+ G + D E+ DQ
Sbjct: 284 EAELAGFSPVVDVKKTALALAITDSELSDEEASILESGGFSVSRATTPQLTDVSEDLDQQ 343
Query: 177 AEEGPPVQSL-----KGEDAEESLEEEEALDPLGIMRSKKPKKHPKVAVKAKPSP-RL-- 228
+ P ++L +GE+ E + E+ P + R + + V AK + RL
Sbjct: 344 SLPSEPEETLSRDLGEGEEGELAPPEDLLGRPQALSRQALDSEEEEEDVAAKETLLRLSS 403
Query: 229 ------TIFDEEVDPDEGLF----GPGRKLSPQDPSEDVSSVDPLKLFDDPDLGGAIPL- 277
T F+ P +G+ GP LSP+ S ++++ P L L G+ P
Sbjct: 404 PLHFVNTHFNGAGSPPDGVKCSPGGPVETLSPETVSGGLTAL-PGTLSPPLCLVGSDPAP 462
Query: 278 GDSLLLPAACESGGPTPSLSHRDA-SKELFRVEEDLDQILNLGAEPKPKPQLKPKPPVAA 336
S+L P +S P P+ +A + E F + D ++ L AE +P+ PKPP A
Sbjct: 463 SPSILPPVPQDSPQPLPAPEEEEALTTEDFELL-DQGELEQLNAELGLEPETPPKPP-DA 520
Query: 337 KPVIPRKPAVPPKAGPAEAVA 357
P+ P ++ A+AVA
Sbjct: 521 PPLGPDIHSLVQSDQEAQAVA 541
>gi|90903231 huntingtin [Homo sapiens]
Length = 3144
Score = 38.9 bits (89), Expect = 0.008
Identities = 20/51 (39%), Positives = 30/51 (58%), Gaps = 5/51 (9%)
Query: 322 PKPKPQLKPKPPVAAKPVIPR----KPAVPPKAGPAEAVAGQQKPQEQIQA 368
P P PQL P+PP A+P++P+ P PP GPA A +P++++ A
Sbjct: 47 PPPPPQL-PQPPPQAQPLLPQPQPPPPPPPPPPGPAVAEEPLHRPKKELSA 96
>gi|67188445 CTD (carboxy-terminal domain, RNA polymerase II,
polypeptide A) phosphatase, subunit 1 isoform FCP1a
[Homo sapiens]
Length = 961
Score = 38.5 bits (88), Expect = 0.011
Identities = 52/237 (21%), Positives = 95/237 (40%), Gaps = 42/237 (17%)
Query: 162 NDEEAFDFFEEQDQVAEEGPPVQS----LKGEDAEESLEEEEALDPLGIMRSKKPKKHPK 217
N + + E D+V E+ P++ + E++ + + E + P + HP
Sbjct: 707 NPDWLWSCLERWDKVEEQLFPLRDDHTKAQRENSPAAFPDREGVPPTALF-------HPM 759
Query: 218 -VAVKAKPSPRLTIFDEEVDPDEGLFGPGRKLSPQDPSEDVSSVDPLKLFDDPDLGGAIP 276
V KA+P P + I+D L G + P PS L + +P A+P
Sbjct: 760 PVLPKAQPGPEVRIYDSNTGK---LIRTGAR-GPPAPSSS------LPIRQEPSSFRAVP 809
Query: 277 LGDSLL----LPAACESGGPTPSLSHRDAS------------KELFRVEEDLDQILNLGA 320
+ LP A + P PS R S ++L +++++D IL G+
Sbjct: 810 PPQPQMFGEELPDAQDGEQPGPSRRKRQPSMSETMPLYTLCKEDLESMDKEVDDILGEGS 869
Query: 321 EP----KPKPQLKPKPPVAAKPVIPRKPAVPPKAGPAEAVAGQQKPQEQIQAMDEMD 373
+ K +P+ + + P KP R+ + A + AG + P+ + ++E D
Sbjct: 870 DDSDSEKRRPEEQEEEPQPRKPGTRRERTLGAPASSERSAAGGRGPRGHKRKLNEED 926
>gi|239787762 SH2 domain protein 2A isoform 4 [Homo sapiens]
Length = 361
Score = 38.1 bits (87), Expect = 0.014
Identities = 22/72 (30%), Positives = 33/72 (45%), Gaps = 2/72 (2%)
Query: 321 EPKPKPQLKPKPPVAAKPVIPRKPAVPPKAGPAEAVAGQQKPQEQIQAMDEMDILQYIQD 380
E +P L+PKPP+ AKP +P P V P A + KP I + I Y
Sbjct: 208 EKEPSQLLRPKPPIPAKPQLP--PEVYTIPVPRHRPAPRPKPSNPIYNEPDEPIAFYAMG 265
Query: 381 HDTPAQAAPSLF 392
+P +A +++
Sbjct: 266 RGSPGEAPSNIY 277
>gi|239787758 SH2 domain protein 2A isoform 3 [Homo sapiens]
Length = 371
Score = 38.1 bits (87), Expect = 0.014
Identities = 22/72 (30%), Positives = 33/72 (45%), Gaps = 2/72 (2%)
Query: 321 EPKPKPQLKPKPPVAAKPVIPRKPAVPPKAGPAEAVAGQQKPQEQIQAMDEMDILQYIQD 380
E +P L+PKPP+ AKP +P P V P A + KP I + I Y
Sbjct: 218 EKEPSQLLRPKPPIPAKPQLP--PEVYTIPVPRHRPAPRPKPSNPIYNEPDEPIAFYAMG 275
Query: 381 HDTPAQAAPSLF 392
+P +A +++
Sbjct: 276 RGSPGEAPSNIY 287
>gi|239787752 SH2 domain protein 2A isoform 1 [Homo sapiens]
Length = 399
Score = 38.1 bits (87), Expect = 0.014
Identities = 22/72 (30%), Positives = 33/72 (45%), Gaps = 2/72 (2%)
Query: 321 EPKPKPQLKPKPPVAAKPVIPRKPAVPPKAGPAEAVAGQQKPQEQIQAMDEMDILQYIQD 380
E +P L+PKPP+ AKP +P P V P A + KP I + I Y
Sbjct: 246 EKEPSQLLRPKPPIPAKPQLP--PEVYTIPVPRHRPAPRPKPSNPIYNEPDEPIAFYAMG 303
Query: 381 HDTPAQAAPSLF 392
+P +A +++
Sbjct: 304 RGSPGEAPSNIY 315
>gi|239787750 SH2 domain protein 2A isoform 2 [Homo sapiens]
Length = 389
Score = 38.1 bits (87), Expect = 0.014
Identities = 22/72 (30%), Positives = 33/72 (45%), Gaps = 2/72 (2%)
Query: 321 EPKPKPQLKPKPPVAAKPVIPRKPAVPPKAGPAEAVAGQQKPQEQIQAMDEMDILQYIQD 380
E +P L+PKPP+ AKP +P P V P A + KP I + I Y
Sbjct: 236 EKEPSQLLRPKPPIPAKPQLP--PEVYTIPVPRHRPAPRPKPSNPIYNEPDEPIAFYAMG 293
Query: 381 HDTPAQAAPSLF 392
+P +A +++
Sbjct: 294 RGSPGEAPSNIY 305
>gi|239787783 SH2 domain protein 2A isoform 2 [Homo sapiens]
Length = 389
Score = 38.1 bits (87), Expect = 0.014
Identities = 22/72 (30%), Positives = 33/72 (45%), Gaps = 2/72 (2%)
Query: 321 EPKPKPQLKPKPPVAAKPVIPRKPAVPPKAGPAEAVAGQQKPQEQIQAMDEMDILQYIQD 380
E +P L+PKPP+ AKP +P P V P A + KP I + I Y
Sbjct: 236 EKEPSQLLRPKPPIPAKPQLP--PEVYTIPVPRHRPAPRPKPSNPIYNEPDEPIAFYAMG 293
Query: 381 HDTPAQAAPSLF 392
+P +A +++
Sbjct: 294 RGSPGEAPSNIY 305
>gi|46370089 sorting nexin 15 isoform B [Homo sapiens]
Length = 256
Score = 37.7 bits (86), Expect = 0.018
Identities = 33/105 (31%), Positives = 48/105 (45%), Gaps = 13/105 (12%)
Query: 37 GHVEYQILVVTRLAAFKSAKHRPEDVVQFLVSKKYSEIEEFYQKLSSRY-----AAASLP 91
G+ EY++ A F S K PEDV + +V K+YS+ + + L+ + P
Sbjct: 24 GYTEYKVT-----AQFISKKD-PEDVKEVVVWKRYSDFRKLHGDLAYTHRNLFRRLEEFP 77
Query: 92 PLPRKVLF--VGESDIRERRAVFNEILRCVSKDAELAGSPELLEF 134
PR +F S I ERR ++LR L SP+L EF
Sbjct: 78 AFPRAQVFGRFEASVIEERRKGAEDLLRFTVHIPALNNSPQLKEF 122
>gi|22547191 sorting nexin 15 isoform A [Homo sapiens]
Length = 342
Score = 37.7 bits (86), Expect = 0.018
Identities = 33/105 (31%), Positives = 48/105 (45%), Gaps = 13/105 (12%)
Query: 37 GHVEYQILVVTRLAAFKSAKHRPEDVVQFLVSKKYSEIEEFYQKLSSRY-----AAASLP 91
G+ EY++ A F S K PEDV + +V K+YS+ + + L+ + P
Sbjct: 24 GYTEYKVT-----AQFISKKD-PEDVKEVVVWKRYSDFRKLHGDLAYTHRNLFRRLEEFP 77
Query: 92 PLPRKVLF--VGESDIRERRAVFNEILRCVSKDAELAGSPELLEF 134
PR +F S I ERR ++LR L SP+L EF
Sbjct: 78 AFPRAQVFGRFEASVIEERRKGAEDLLRFTVHIPALNNSPQLKEF 122
>gi|63054866 leucine rich repeat containing 16A [Homo sapiens]
Length = 1326
Score = 37.4 bits (85), Expect = 0.024
Identities = 43/162 (26%), Positives = 63/162 (38%), Gaps = 13/162 (8%)
Query: 187 KGEDAEESLEEEEALDPLGIMRSKK---PKKHPKVAVKAKPSPRLTIFDEEVDPDEGLFG 243
K E L EE P G +RS P+K K A S R+ +E PD
Sbjct: 1079 KSERPPTILMTEEPSSPKGAVRSPPVDCPRKDTKAAEHNGNSERI---EEIKTPDSFEES 1135
Query: 244 PGRKLSPQDPSEDVSSVDPLKLFDDPDLGGAIPLGDSLLLPAACESGGPTPSLSHRDASK 303
G ++ + S+ SS + + G +G LL + + +K
Sbjct: 1136 QGEEIGKVERSDSKSSPQAGRRY------GVQVMGSGLLAEMKAKQENRFGLGTPEKNTK 1189
Query: 304 ELFRVEEDLDQILNLGAEPKPKPQLK-PKPPVAAKPVIPRKP 344
+ E + PKP L+ PKP +AA+PVIP+KP
Sbjct: 1190 AEPKAEAGSRSRSSSSTPTSPKPLLQSPKPSLAARPVIPQKP 1231
>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
Length = 841
Score = 37.4 bits (85), Expect = 0.024
Identities = 47/220 (21%), Positives = 73/220 (33%), Gaps = 49/220 (22%)
Query: 179 EGPPVQSLKGEDAEESLEEEEALDPLGIMRSKKPKKHPKVAV------------------ 220
E PVQ + +D E E+E++ + R + KK +
Sbjct: 408 EASPVQKKEKKDKERENEKEKS----ALARERSLKKRQSLPASPRARLSASTASELSPKS 463
Query: 221 KAKPSPRLTIFDEEVDPDEGLFGPGRKLSPQDPSEDVSSVDPLKLFDDPDLGGAIPLGDS 280
KA+PS T + P GPG L P+ PS ++ P + P
Sbjct: 464 KARPSSPSTSWHRPASPCPSP-GPGHTLPPKPPSPRGTTASPKGRVRRKEEAKESP---- 518
Query: 281 LLLPAACESGGPTPSLSHRDASKELFRVEEDLDQILNLGAEPKPKPQLKPKPPVAAKP-- 338
+ GP D S+ R + + P P P P PP +P
Sbjct: 519 -------SAAGP------EDKSQSKRRASNEKESAAPASPAPSPAPSPTPAPPQKEQPPA 565
Query: 339 -------VIPRKPAVPPKAGPAEAVAGQQKPQEQIQAMDE 371
V+ PA P P++ +AG +E + + E
Sbjct: 566 ETPTDAAVLTSPPAPAPPVTPSKPMAGTTDREEATRLLAE 605
Score = 29.6 bits (65), Expect = 4.9
Identities = 17/46 (36%), Positives = 22/46 (47%), Gaps = 4/46 (8%)
Query: 321 EPKPKPQLKPKPPVAAKPVIPRKPAVPPKAGPA--EAVAGQQKPQE 364
EP+P P+ P PP P+ P PP PA A + +Q P E
Sbjct: 24 EPRPSPEGDPSPP--PPPMSALVPDTPPDTPPAMKNATSSKQLPLE 67
>gi|56549666 tyrosine kinase, non-receptor, 2 isoform 1 [Homo
sapiens]
Length = 1038
Score = 36.6 bits (83), Expect = 0.040
Identities = 61/233 (26%), Positives = 91/233 (39%), Gaps = 37/233 (15%)
Query: 135 LGTRSPGAA-GL-TSRDSSVLDGTDSQTGNDEEA--FDFFEEQDQVA-EEGPPVQSLKGE 189
LG R PG GL ++ S+ + GT + G+ E DF EE A P +
Sbjct: 535 LGLRKPGLPRGLWLAKPSARVPGTKASRGSGAEVTLIDFGEEPVVPALRPCAPSLAQLAM 594
Query: 190 DAEESLEEEEALDPLGIMRSKKPKKHPKVAVK--AKPSPRLTIFDEEVDPDEG------- 240
DA L+E P R+ HP V A+P P +D+ ++
Sbjct: 595 DACSLLDETPPQSPT---RALPRPLHPTPVVDWDARPLPPPPAYDDVAQDEDDFEICSIN 651
Query: 241 --LFGPGRKLSPQDPSEDVSSVDPLKLFDDPDLGGAIPLGDSLLLPAACESGGPTPSLSH 298
L G G P + + V P + P PL D+L LP + GG PS +
Sbjct: 652 STLVGAGVPAGPSQGQTNYAFV-PEQARPPP------PLEDNLFLPP--QGGGKPPSSAQ 702
Query: 299 RDASKELFRV--EEDLDQILNLGAEPKPKPQLKPKPPVAAKPVIPRKPAVPPK 349
+ E+F+ +E + Q+ P P P P KP +P + +PP+
Sbjct: 703 ---TAEIFQALQQECMRQLQAPAGSPAPSPS----PGGDDKPQVPPRVPIPPR 748
>gi|58331191 tyrosine kinase, non-receptor, 2 isoform 2 [Homo
sapiens]
Length = 1086
Score = 36.6 bits (83), Expect = 0.040
Identities = 61/233 (26%), Positives = 91/233 (39%), Gaps = 37/233 (15%)
Query: 135 LGTRSPGAA-GL-TSRDSSVLDGTDSQTGNDEEA--FDFFEEQDQVA-EEGPPVQSLKGE 189
LG R PG GL ++ S+ + GT + G+ E DF EE A P +
Sbjct: 613 LGLRKPGLPRGLWLAKPSARVPGTKASRGSGAEVTLIDFGEEPVVPALRPCAPSLAQLAM 672
Query: 190 DAEESLEEEEALDPLGIMRSKKPKKHPKVAVK--AKPSPRLTIFDEEVDPDEG------- 240
DA L+E P R+ HP V A+P P +D+ ++
Sbjct: 673 DACSLLDETPPQSPT---RALPRPLHPTPVVDWDARPLPPPPAYDDVAQDEDDFEICSIN 729
Query: 241 --LFGPGRKLSPQDPSEDVSSVDPLKLFDDPDLGGAIPLGDSLLLPAACESGGPTPSLSH 298
L G G P + + V P + P PL D+L LP + GG PS +
Sbjct: 730 STLVGAGVPAGPSQGQTNYAFV-PEQARPPP------PLEDNLFLPP--QGGGKPPSSAQ 780
Query: 299 RDASKELFRV--EEDLDQILNLGAEPKPKPQLKPKPPVAAKPVIPRKPAVPPK 349
+ E+F+ +E + Q+ P P P P KP +P + +PP+
Sbjct: 781 ---TAEIFQALQQECMRQLQAPAGSPAPSPS----PGGDDKPQVPPRVPIPPR 826
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 36.6 bits (83), Expect = 0.040
Identities = 35/119 (29%), Positives = 47/119 (39%), Gaps = 18/119 (15%)
Query: 251 QDPSEDVSSVDPLKLFDDPDLGG----AIPLGDSLLLPAACESGGPTPSL--SHRDASKE 304
+D E +SS + DDP L G + P G L AA P P L ++ + + E
Sbjct: 1392 RDLQESISSA--ISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPE 1449
Query: 305 LFRVEEDLDQILNLGAEPKPKPQLKPKPP----------VAAKPVIPRKPAVPPKAGPA 353
+EE P+P+P P PP VA P P P +PP PA
Sbjct: 1450 PPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPA 1508
Score = 33.9 bits (76), Expect = 0.26
Identities = 55/210 (26%), Positives = 76/210 (36%), Gaps = 35/210 (16%)
Query: 199 EALDPLGIMRSKKPK--KHPK-VAVKAKPSPRLTIFDEE---VDPDEGLFGPGRKLSPQD 252
E DP G RS P+ K P+ V + + P + DEE E +FG G
Sbjct: 905 EGKDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGA------ 958
Query: 253 PSEDVSSVDPLKLFDDPDLGGAIPLGDSLLLP-------AACESGGPTPSLSHRDASKEL 305
++D P + DP G P G P A +G TP L D +K
Sbjct: 959 -ADDYGKAGPPEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLG-LDPNKP- 1015
Query: 306 FRVEEDLDQILNLGAEPKPKPQLKPK---PPVAAKPVIPRKPAVPPKAGPAEAVAGQQKP 362
+L +N AEP Q P PP P P PA PK G + KP
Sbjct: 1016 ----PELPSTVN--AEPLGLIQSGPHQAAPPPPPPPPPPPAPASEPKGGLTSPIFCSTKP 1069
Query: 363 QEQIQAMDEMDILQYIQDHDTPAQAAPSLF 392
++ ++ ++ D P Q L+
Sbjct: 1070 KKLLKTSS----FHLLRRRDPPFQTPKKLY 1095
Score = 31.2 bits (69), Expect = 1.7
Identities = 15/38 (39%), Positives = 16/38 (42%)
Query: 320 AEPKPKPQLKPKPPVAAKPVIPRKPAVPPKAGPAEAVA 357
+ P P P P PP P P PA P A P E A
Sbjct: 1494 SSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPA 1531
Score = 30.0 bits (66), Expect = 3.8
Identities = 57/210 (27%), Positives = 75/210 (35%), Gaps = 41/210 (19%)
Query: 185 SLKGEDAEESLEEEEALDP---LGIMRS-----KKPKKHPKVAVKAKPSPRLTIFDEEVD 236
SL E E ++E E P G M S K K+HP + +A +P L+ + V
Sbjct: 1257 SLTREKIEAKIKEVEEKQPEMKSGFMASFLDFLKSGKRHPPL-YQAGLTPPLSP-PKSVP 1314
Query: 237 PDEGLFGPGRKLSPQDPSED-VSSVDPLKLFDDPDLGGAIPLGDSLLLPAACESG----- 290
P P R L PQ P+ V P F LGGA+ +S L C S
Sbjct: 1315 PSV----PARGLQPQPPATPAVPHPPPSGAFG---LGGALEAAESEGLGLGCPSPCKRLD 1367
Query: 291 -------GPTPSLS---------HRDASKELFRVEEDLDQILNLGAEPKPKPQLKPKPPV 334
PS S +RD + + LD G + P P P
Sbjct: 1368 EELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPA 1427
Query: 335 AAKPVIPRKPAVPP--KAGPAEAVAGQQKP 362
AA P P P +P G E ++KP
Sbjct: 1428 AAVPGPPPLPGLPSANSNGTPEPPLLEEKP 1457
>gi|237757312 synaptojanin 1 isoform c [Homo sapiens]
Length = 1295
Score = 36.2 bits (82), Expect = 0.052
Identities = 51/188 (27%), Positives = 69/188 (36%), Gaps = 27/188 (14%)
Query: 185 SLKGEDAEESLEEEEALDPLGIMRSKKPKKHPKVAVKAKPSPRLTIFDEEVDPDEGLFGP 244
+LK D ++LEEE +L+ + I A+ + S L D EV D + G
Sbjct: 967 ALKSPDWIKNLEEEMSLEKISI------------ALPSSTSSTLLGEDAEVAADFDMEG- 1013
Query: 245 GRKLSPQDPSEDVSSVDPLKLFDDPDLG-GAIPLGDSLLLPAACE--SGGPTPSLSHRDA 301
D S +V + P L G G P P S GP PSL R +
Sbjct: 1014 ----DVDDYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPS 1069
Query: 302 SKELFRVEEDLDQILNLGAEPK-PKPQ------LKPKPPVAAKPVIPRKPAVPPKAGPAE 354
Q + A+P P PQ L+PK P +PV P PP+ P
Sbjct: 1070 RAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPP 1129
Query: 355 AVAGQQKP 362
+ A P
Sbjct: 1130 SGARSPAP 1137
>gi|237757310 synaptojanin 1 isoform a [Homo sapiens]
Length = 1612
Score = 36.2 bits (82), Expect = 0.052
Identities = 51/188 (27%), Positives = 69/188 (36%), Gaps = 27/188 (14%)
Query: 185 SLKGEDAEESLEEEEALDPLGIMRSKKPKKHPKVAVKAKPSPRLTIFDEEVDPDEGLFGP 244
+LK D ++LEEE +L+ + I A+ + S L D EV D + G
Sbjct: 1006 ALKSPDWIKNLEEEMSLEKISI------------ALPSSTSSTLLGEDAEVAADFDMEG- 1052
Query: 245 GRKLSPQDPSEDVSSVDPLKLFDDPDLG-GAIPLGDSLLLPAACE--SGGPTPSLSHRDA 301
D S +V + P L G G P P S GP PSL R +
Sbjct: 1053 ----DVDDYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPS 1108
Query: 302 SKELFRVEEDLDQILNLGAEPK-PKPQ------LKPKPPVAAKPVIPRKPAVPPKAGPAE 354
Q + A+P P PQ L+PK P +PV P PP+ P
Sbjct: 1109 RAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPP 1168
Query: 355 AVAGQQKP 362
+ A P
Sbjct: 1169 SGARSPAP 1176
>gi|237757308 synaptojanin 1 isoform b [Homo sapiens]
Length = 1350
Score = 36.2 bits (82), Expect = 0.052
Identities = 51/188 (27%), Positives = 69/188 (36%), Gaps = 27/188 (14%)
Query: 185 SLKGEDAEESLEEEEALDPLGIMRSKKPKKHPKVAVKAKPSPRLTIFDEEVDPDEGLFGP 244
+LK D ++LEEE +L+ + I A+ + S L D EV D + G
Sbjct: 1006 ALKSPDWIKNLEEEMSLEKISI------------ALPSSTSSTLLGEDAEVAADFDMEG- 1052
Query: 245 GRKLSPQDPSEDVSSVDPLKLFDDPDLG-GAIPLGDSLLLPAACE--SGGPTPSLSHRDA 301
D S +V + P L G G P P S GP PSL R +
Sbjct: 1053 ----DVDDYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPS 1108
Query: 302 SKELFRVEEDLDQILNLGAEPK-PKPQ------LKPKPPVAAKPVIPRKPAVPPKAGPAE 354
Q + A+P P PQ L+PK P +PV P PP+ P
Sbjct: 1109 RAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPP 1168
Query: 355 AVAGQQKP 362
+ A P
Sbjct: 1169 SGARSPAP 1176
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.132 0.374
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,962,011
Number of Sequences: 37866
Number of extensions: 1016251
Number of successful extensions: 6846
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 82
Number of HSP's successfully gapped in prelim test: 308
Number of HSP's that attempted gapping in prelim test: 5630
Number of HSP's gapped (non-prelim): 1267
length of query: 392
length of database: 18,247,518
effective HSP length: 104
effective length of query: 288
effective length of database: 14,309,454
effective search space: 4121122752
effective search space used: 4121122752
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.