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Search of human proteins with 68299793
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|68299793 serine protease inhibitor, Kazal type 6 [Homo
sapiens]
(80 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|68299793 serine protease inhibitor, Kazal type 6 [Homo sapiens] 174 1e-44
gi|94536774 serine peptidase inhibitor, Kazal type 9 [Homo sapiens] 52 1e-07
gi|189163504 serine peptidase inhibitor, Kazal type 5 isoform c ... 51 2e-07
gi|74027261 serine peptidase inhibitor, Kazal type 5 isoform b p... 51 2e-07
gi|189163501 serine peptidase inhibitor, Kazal type 5 isoform a ... 51 2e-07
gi|14211875 esophagus cancer-related gene-2 [Homo sapiens] 50 4e-07
gi|45505132 serine protease inhibitor, Kazal type 1 precursor [H... 49 9e-07
gi|10863911 serine protease inhibitor, Kazal type 2 (acrosin-try... 49 1e-06
gi|19923632 Kazal-type serine peptidase inhibitor domain 1 precu... 43 6e-05
gi|7657453 serine peptidase inhibitor, Kazal type 4 [Homo sapiens] 43 6e-05
gi|5453652 follistatin isoform FST317 precursor [Homo sapiens] 39 7e-04
gi|7242222 follistatin isoform FST344 precursor [Homo sapiens] 39 7e-04
gi|47679099 Kazal type serine protease inhibitor 5-like 2 [Homo ... 39 0.001
gi|5901956 follistatin-like 1 precursor [Homo sapiens] 38 0.002
gi|190358524 follistatin-like 5 isoform c [Homo sapiens] 36 0.006
gi|190358522 follistatin-like 5 isoform b [Homo sapiens] 36 0.006
gi|190358520 follistatin-like 5 isoform a [Homo sapiens] 36 0.006
gi|54873613 agrin [Homo sapiens] 36 0.008
gi|122937482 serine peptidase inhibitor, Kazal type 8 (putative)... 35 0.013
gi|12383051 transmembrane protein with EGF-like and two follista... 34 0.029
gi|29568105 transmembrane protein with EGF-like and two follista... 33 0.049
gi|93141003 testican 3 isoform 1 [Homo sapiens] 32 0.084
gi|93141001 testican 3 isoform 2 [Homo sapiens] 32 0.084
gi|54792136 follistatin-like 4 [Homo sapiens] 32 0.084
gi|118600977 C3 and PZP-like, alpha-2-macroglobulin domain conta... 32 0.084
gi|92110017 serine PI Kazal type 5-like 3 [Homo sapiens] 32 0.084
gi|148298722 zinc finger protein 185 [Homo sapiens] 31 0.19
gi|22129776 HtrA serine peptidase 3 [Homo sapiens] 31 0.19
gi|5031701 follistatin-like 3 glycoprotein precursor [Homo sapiens] 30 0.42
gi|78190498 secreted modular calcium-binding protein 1 isoform 1... 30 0.42
>gi|68299793 serine protease inhibitor, Kazal type 6 [Homo
sapiens]
Length = 80
Score = 174 bits (442), Expect = 1e-44
Identities = 80/80 (100%), Positives = 80/80 (100%)
Query: 1 MKLSGMFLLLSLALFCFLTGVFSQGGQVDCGEFQDPKVYCTRESNPHCGSDGQTYGNKCA 60
MKLSGMFLLLSLALFCFLTGVFSQGGQVDCGEFQDPKVYCTRESNPHCGSDGQTYGNKCA
Sbjct: 1 MKLSGMFLLLSLALFCFLTGVFSQGGQVDCGEFQDPKVYCTRESNPHCGSDGQTYGNKCA 60
Query: 61 FCKAIVKSGGKISLKHPGKC 80
FCKAIVKSGGKISLKHPGKC
Sbjct: 61 FCKAIVKSGGKISLKHPGKC 80
>gi|94536774 serine peptidase inhibitor, Kazal type 9 [Homo
sapiens]
Length = 86
Score = 52.0 bits (123), Expect = 1e-07
Identities = 31/86 (36%), Positives = 44/86 (51%), Gaps = 6/86 (6%)
Query: 1 MKLSGMFLLLSLALFC-FLTGVFSQGGQ-VDCGEFQD----PKVYCTRESNPHCGSDGQT 54
M+ + + LLL+L L F Q Q VDC ++ + +C +P CGSDG+T
Sbjct: 1 MRATAIVLLLALTLATMFSIECAKQTKQMVDCSHYKKLPPGQQRFCHHMYDPICGSDGKT 60
Query: 55 YGNKCAFCKAIVKSGGKISLKHPGKC 80
Y N C FC + K+ G + H GKC
Sbjct: 61 YKNDCFFCSKVKKTDGTLKFVHFGKC 86
>gi|189163504 serine peptidase inhibitor, Kazal type 5 isoform c
precursor [Homo sapiens]
Length = 916
Score = 50.8 bits (120), Expect = 2e-07
Identities = 22/40 (55%), Positives = 30/40 (75%), Gaps = 4/40 (10%)
Query: 30 CGEF----QDPKVYCTRESNPHCGSDGQTYGNKCAFCKAI 65
C EF Q+ K++CTRE++P G DG+T+GNKCA CKA+
Sbjct: 632 CDEFRRLLQNGKLFCTRENDPVRGPDGKTHGNKCAMCKAV 671
Score = 49.3 bits (116), Expect = 7e-07
Identities = 23/48 (47%), Positives = 30/48 (62%), Gaps = 4/48 (8%)
Query: 20 GVFSQGGQVDCGEFQDP----KVYCTRESNPHCGSDGQTYGNKCAFCK 63
G S+ G+ C EF+ K+ CTRES+P G DG+T+GNKC CK
Sbjct: 764 GTGSESGKDTCDEFRSQMKNGKLICTRESDPVRGPDGKTHGNKCTMCK 811
Score = 45.8 bits (107), Expect = 7e-06
Identities = 20/58 (34%), Positives = 32/58 (55%), Gaps = 4/58 (6%)
Query: 27 QVDCGEFQ----DPKVYCTRESNPHCGSDGQTYGNKCAFCKAIVKSGGKISLKHPGKC 80
+++C +F+ D C CG+DG+TY N+CA C K+G +I +K G+C
Sbjct: 94 ELNCDDFKKGERDGDFICPDYYEAVCGTDGKTYDNRCALCAENAKTGSQIGVKSEGEC 151
Score = 45.1 bits (105), Expect = 1e-05
Identities = 20/42 (47%), Positives = 26/42 (61%), Gaps = 4/42 (9%)
Query: 30 CGEFQDP----KVYCTRESNPHCGSDGQTYGNKCAFCKAIVK 67
C EF+D + CTRE NP G DG+ +GNKCA C ++ K
Sbjct: 496 CSEFRDQVRNGTLICTREHNPVRGPDGKMHGNKCAMCASVFK 537
Score = 43.5 bits (101), Expect = 4e-05
Identities = 17/36 (47%), Positives = 26/36 (72%)
Query: 32 EFQDPKVYCTRESNPHCGSDGQTYGNKCAFCKAIVK 67
+ ++ +++CTRES+P G DG+ +GNKCA C I K
Sbjct: 231 QVRNGRLFCTRESDPVRGPDGRMHGNKCALCAEIFK 266
Score = 42.4 bits (98), Expect = 8e-05
Identities = 16/29 (55%), Positives = 23/29 (79%)
Query: 34 QDPKVYCTRESNPHCGSDGQTYGNKCAFC 62
+D ++ CTRE++P G DG+T+GNKCA C
Sbjct: 169 RDGRLGCTRENDPVLGPDGKTHGNKCAMC 197
Score = 40.8 bits (94), Expect = 2e-04
Identities = 17/42 (40%), Positives = 28/42 (66%), Gaps = 4/42 (9%)
Query: 27 QVDCGEFQDP----KVYCTRESNPHCGSDGQTYGNKCAFCKA 64
Q +C E+++ ++ CTRES+P +DG++Y N+C CKA
Sbjct: 704 QDECAEYREQMKNGRLSCTRESDPVRDADGKSYNNQCTMCKA 745
Score = 39.7 bits (91), Expect = 5e-04
Identities = 18/54 (33%), Positives = 31/54 (57%), Gaps = 4/54 (7%)
Query: 30 CGEFQ----DPKVYCTRESNPHCGSDGQTYGNKCAFCKAIVKSGGKISLKHPGK 79
C E++ + K+ CTRE++P G DG+ +GN C+ C+ ++ + K GK
Sbjct: 367 CSEYRKLVRNGKLACTRENDPIQGPDGKVHGNTCSMCEVFFQAEEEEKKKKEGK 420
Score = 38.9 bits (89), Expect = 9e-04
Identities = 15/39 (38%), Positives = 27/39 (69%), Gaps = 4/39 (10%)
Query: 30 CGEFQ----DPKVYCTRESNPHCGSDGQTYGNKCAFCKA 64
C E++ + +++CTRE++P G DG+ +GN C+ C+A
Sbjct: 437 CSEYRKSRKNGRLFCTRENDPIQGPDGKMHGNTCSMCEA 475
Score = 38.1 bits (87), Expect = 0.002
Identities = 24/75 (32%), Positives = 36/75 (48%), Gaps = 4/75 (5%)
Query: 1 MKLSGMFLLLSLALFCFLTGVFSQGGQVDCGEFQ----DPKVYCTRESNPHCGSDGQTYG 56
MK++ + +LL LAL Q C EFQ + K++C ++ DG +
Sbjct: 1 MKIATVSVLLPLALCLIQDAASKNEDQEMCHEFQAFMKNGKLFCPQDKKFFQSLDGIMFI 60
Query: 57 NKCAFCKAIVKSGGK 71
NKCA CK I++ K
Sbjct: 61 NKCATCKMILEKEAK 75
Score = 38.1 bits (87), Expect = 0.002
Identities = 15/39 (38%), Positives = 26/39 (66%), Gaps = 4/39 (10%)
Query: 30 CGEFQDPK----VYCTRESNPHCGSDGQTYGNKCAFCKA 64
C ++Q+ ++CTRE++P G DG+ +GN C+ C+A
Sbjct: 297 CSQYQNQAKNGILFCTRENDPIRGPDGKMHGNLCSMCQA 335
Score = 38.1 bits (87), Expect = 0.002
Identities = 21/51 (41%), Positives = 30/51 (58%), Gaps = 4/51 (7%)
Query: 19 TGVFSQGGQVDCGEFQ----DPKVYCTRESNPHCGSDGQTYGNKCAFCKAI 65
TG S + C EF+ + K+ CTRE+NP G G+ + NKCA C++I
Sbjct: 838 TGERSNDKEDLCREFRSMQRNGKLICTRENNPVRGPYGKMHINKCAMCQSI 888
Score = 37.0 bits (84), Expect = 0.003
Identities = 16/46 (34%), Positives = 28/46 (60%), Gaps = 4/46 (8%)
Query: 30 CGEFQ----DPKVYCTRESNPHCGSDGQTYGNKCAFCKAIVKSGGK 71
C E++ + ++ CTRE++P G DG+ +GN C+ C+A + K
Sbjct: 567 CSEYRHYVRNGRLPCTRENDPIEGLDGKIHGNTCSMCEAFFQQEAK 612
>gi|74027261 serine peptidase inhibitor, Kazal type 5 isoform b
precursor [Homo sapiens]
Length = 1064
Score = 50.8 bits (120), Expect = 2e-07
Identities = 22/40 (55%), Positives = 30/40 (75%), Gaps = 4/40 (10%)
Query: 30 CGEF----QDPKVYCTRESNPHCGSDGQTYGNKCAFCKAI 65
C EF Q+ K++CTRE++P G DG+T+GNKCA CKA+
Sbjct: 632 CDEFRRLLQNGKLFCTRENDPVRGPDGKTHGNKCAMCKAV 671
Score = 49.3 bits (116), Expect = 7e-07
Identities = 23/48 (47%), Positives = 30/48 (62%), Gaps = 4/48 (8%)
Query: 20 GVFSQGGQVDCGEFQDP----KVYCTRESNPHCGSDGQTYGNKCAFCK 63
G S+ G+ C EF+ K+ CTRES+P G DG+T+GNKC CK
Sbjct: 764 GTGSESGKDTCDEFRSQMKNGKLICTRESDPVRGPDGKTHGNKCTMCK 811
Score = 45.8 bits (107), Expect = 7e-06
Identities = 20/58 (34%), Positives = 32/58 (55%), Gaps = 4/58 (6%)
Query: 27 QVDCGEFQ----DPKVYCTRESNPHCGSDGQTYGNKCAFCKAIVKSGGKISLKHPGKC 80
+++C +F+ D C CG+DG+TY N+CA C K+G +I +K G+C
Sbjct: 94 ELNCDDFKKGERDGDFICPDYYEAVCGTDGKTYDNRCALCAENAKTGSQIGVKSEGEC 151
Score = 45.1 bits (105), Expect = 1e-05
Identities = 20/42 (47%), Positives = 26/42 (61%), Gaps = 4/42 (9%)
Query: 30 CGEFQDP----KVYCTRESNPHCGSDGQTYGNKCAFCKAIVK 67
C EF+D + CTRE NP G DG+ +GNKCA C ++ K
Sbjct: 496 CSEFRDQVRNGTLICTREHNPVRGPDGKMHGNKCAMCASVFK 537
Score = 43.5 bits (101), Expect = 4e-05
Identities = 17/36 (47%), Positives = 26/36 (72%)
Query: 32 EFQDPKVYCTRESNPHCGSDGQTYGNKCAFCKAIVK 67
+ ++ +++CTRES+P G DG+ +GNKCA C I K
Sbjct: 231 QVRNGRLFCTRESDPVRGPDGRMHGNKCALCAEIFK 266
Score = 42.4 bits (98), Expect = 8e-05
Identities = 16/29 (55%), Positives = 23/29 (79%)
Query: 34 QDPKVYCTRESNPHCGSDGQTYGNKCAFC 62
+D ++ CTRE++P G DG+T+GNKCA C
Sbjct: 169 RDGRLGCTRENDPVLGPDGKTHGNKCAMC 197
Score = 40.8 bits (94), Expect = 2e-04
Identities = 17/42 (40%), Positives = 28/42 (66%), Gaps = 4/42 (9%)
Query: 27 QVDCGEFQDP----KVYCTRESNPHCGSDGQTYGNKCAFCKA 64
Q +C E+++ ++ CTRES+P +DG++Y N+C CKA
Sbjct: 704 QDECAEYREQMKNGRLSCTRESDPVRDADGKSYNNQCTMCKA 745
Score = 39.7 bits (91), Expect = 5e-04
Identities = 18/54 (33%), Positives = 31/54 (57%), Gaps = 4/54 (7%)
Query: 30 CGEFQ----DPKVYCTRESNPHCGSDGQTYGNKCAFCKAIVKSGGKISLKHPGK 79
C E++ + K+ CTRE++P G DG+ +GN C+ C+ ++ + K GK
Sbjct: 367 CSEYRKLVRNGKLACTRENDPIQGPDGKVHGNTCSMCEVFFQAEEEEKKKKEGK 420
Score = 39.3 bits (90), Expect = 7e-04
Identities = 17/47 (36%), Positives = 29/47 (61%), Gaps = 4/47 (8%)
Query: 23 SQGGQVDCGEFQD----PKVYCTRESNPHCGSDGQTYGNKCAFCKAI 65
S + +C EF++ ++ C RE++P G+DG+ Y NKC C+A+
Sbjct: 909 SNNAKDECSEFRNYIRNNELICPRENDPVHGADGKFYTNKCYMCRAV 955
Score = 38.9 bits (89), Expect = 9e-04
Identities = 15/39 (38%), Positives = 27/39 (69%), Gaps = 4/39 (10%)
Query: 30 CGEFQ----DPKVYCTRESNPHCGSDGQTYGNKCAFCKA 64
C E++ + +++CTRE++P G DG+ +GN C+ C+A
Sbjct: 437 CSEYRKSRKNGRLFCTRENDPIQGPDGKMHGNTCSMCEA 475
Score = 38.5 bits (88), Expect = 0.001
Identities = 15/41 (36%), Positives = 20/41 (48%)
Query: 40 CTRESNPHCGSDGQTYGNKCAFCKAIVKSGGKISLKHPGKC 80
C ++ P CG DGQTY N C C + ++ GKC
Sbjct: 1006 CPKDLKPVCGDDGQTYNNPCMLCHENLIRQTNTHIRSTGKC 1046
Score = 38.1 bits (87), Expect = 0.002
Identities = 24/75 (32%), Positives = 36/75 (48%), Gaps = 4/75 (5%)
Query: 1 MKLSGMFLLLSLALFCFLTGVFSQGGQVDCGEFQ----DPKVYCTRESNPHCGSDGQTYG 56
MK++ + +LL LAL Q C EFQ + K++C ++ DG +
Sbjct: 1 MKIATVSVLLPLALCLIQDAASKNEDQEMCHEFQAFMKNGKLFCPQDKKFFQSLDGIMFI 60
Query: 57 NKCAFCKAIVKSGGK 71
NKCA CK I++ K
Sbjct: 61 NKCATCKMILEKEAK 75
Score = 38.1 bits (87), Expect = 0.002
Identities = 15/39 (38%), Positives = 26/39 (66%), Gaps = 4/39 (10%)
Query: 30 CGEFQDPK----VYCTRESNPHCGSDGQTYGNKCAFCKA 64
C ++Q+ ++CTRE++P G DG+ +GN C+ C+A
Sbjct: 297 CSQYQNQAKNGILFCTRENDPIRGPDGKMHGNLCSMCQA 335
Score = 38.1 bits (87), Expect = 0.002
Identities = 21/51 (41%), Positives = 30/51 (58%), Gaps = 4/51 (7%)
Query: 19 TGVFSQGGQVDCGEFQ----DPKVYCTRESNPHCGSDGQTYGNKCAFCKAI 65
TG S + C EF+ + K+ CTRE+NP G G+ + NKCA C++I
Sbjct: 838 TGERSNDKEDLCREFRSMQRNGKLICTRENNPVRGPYGKMHINKCAMCQSI 888
Score = 37.0 bits (84), Expect = 0.003
Identities = 16/46 (34%), Positives = 28/46 (60%), Gaps = 4/46 (8%)
Query: 30 CGEFQ----DPKVYCTRESNPHCGSDGQTYGNKCAFCKAIVKSGGK 71
C E++ + ++ CTRE++P G DG+ +GN C+ C+A + K
Sbjct: 567 CSEYRHYVRNGRLPCTRENDPIEGLDGKIHGNTCSMCEAFFQQEAK 612
>gi|189163501 serine peptidase inhibitor, Kazal type 5 isoform a
precursor [Homo sapiens]
Length = 1094
Score = 50.8 bits (120), Expect = 2e-07
Identities = 22/40 (55%), Positives = 30/40 (75%), Gaps = 4/40 (10%)
Query: 30 CGEF----QDPKVYCTRESNPHCGSDGQTYGNKCAFCKAI 65
C EF Q+ K++CTRE++P G DG+T+GNKCA CKA+
Sbjct: 632 CDEFRRLLQNGKLFCTRENDPVRGPDGKTHGNKCAMCKAV 671
Score = 49.3 bits (116), Expect = 7e-07
Identities = 23/48 (47%), Positives = 30/48 (62%), Gaps = 4/48 (8%)
Query: 20 GVFSQGGQVDCGEFQDP----KVYCTRESNPHCGSDGQTYGNKCAFCK 63
G S+ G+ C EF+ K+ CTRES+P G DG+T+GNKC CK
Sbjct: 764 GTGSESGKDTCDEFRSQMKNGKLICTRESDPVRGPDGKTHGNKCTMCK 811
Score = 45.8 bits (107), Expect = 7e-06
Identities = 20/58 (34%), Positives = 32/58 (55%), Gaps = 4/58 (6%)
Query: 27 QVDCGEFQ----DPKVYCTRESNPHCGSDGQTYGNKCAFCKAIVKSGGKISLKHPGKC 80
+++C +F+ D C CG+DG+TY N+CA C K+G +I +K G+C
Sbjct: 94 ELNCDDFKKGERDGDFICPDYYEAVCGTDGKTYDNRCALCAENAKTGSQIGVKSEGEC 151
Score = 45.1 bits (105), Expect = 1e-05
Identities = 20/42 (47%), Positives = 26/42 (61%), Gaps = 4/42 (9%)
Query: 30 CGEFQDP----KVYCTRESNPHCGSDGQTYGNKCAFCKAIVK 67
C EF+D + CTRE NP G DG+ +GNKCA C ++ K
Sbjct: 496 CSEFRDQVRNGTLICTREHNPVRGPDGKMHGNKCAMCASVFK 537
Score = 43.5 bits (101), Expect = 4e-05
Identities = 17/36 (47%), Positives = 26/36 (72%)
Query: 32 EFQDPKVYCTRESNPHCGSDGQTYGNKCAFCKAIVK 67
+ ++ +++CTRES+P G DG+ +GNKCA C I K
Sbjct: 231 QVRNGRLFCTRESDPVRGPDGRMHGNKCALCAEIFK 266
Score = 42.4 bits (98), Expect = 8e-05
Identities = 16/29 (55%), Positives = 23/29 (79%)
Query: 34 QDPKVYCTRESNPHCGSDGQTYGNKCAFC 62
+D ++ CTRE++P G DG+T+GNKCA C
Sbjct: 169 RDGRLGCTRENDPVLGPDGKTHGNKCAMC 197
Score = 40.8 bits (94), Expect = 2e-04
Identities = 17/42 (40%), Positives = 28/42 (66%), Gaps = 4/42 (9%)
Query: 27 QVDCGEFQDP----KVYCTRESNPHCGSDGQTYGNKCAFCKA 64
Q +C E+++ ++ CTRES+P +DG++Y N+C CKA
Sbjct: 704 QDECAEYREQMKNGRLSCTRESDPVRDADGKSYNNQCTMCKA 745
Score = 39.7 bits (91), Expect = 5e-04
Identities = 18/54 (33%), Positives = 31/54 (57%), Gaps = 4/54 (7%)
Query: 30 CGEFQ----DPKVYCTRESNPHCGSDGQTYGNKCAFCKAIVKSGGKISLKHPGK 79
C E++ + K+ CTRE++P G DG+ +GN C+ C+ ++ + K GK
Sbjct: 367 CSEYRKLVRNGKLACTRENDPIQGPDGKVHGNTCSMCEVFFQAEEEEKKKKEGK 420
Score = 38.9 bits (89), Expect = 9e-04
Identities = 15/39 (38%), Positives = 27/39 (69%), Gaps = 4/39 (10%)
Query: 30 CGEFQ----DPKVYCTRESNPHCGSDGQTYGNKCAFCKA 64
C E++ + +++CTRE++P G DG+ +GN C+ C+A
Sbjct: 437 CSEYRKSRKNGRLFCTRENDPIQGPDGKMHGNTCSMCEA 475
Score = 38.5 bits (88), Expect = 0.001
Identities = 16/41 (39%), Positives = 27/41 (65%), Gaps = 4/41 (9%)
Query: 29 DCGEFQD----PKVYCTRESNPHCGSDGQTYGNKCAFCKAI 65
+C EF++ ++ C RE++P G+DG+ Y NKC C+A+
Sbjct: 945 ECSEFRNYIRNNELICPRENDPVHGADGKFYTNKCYMCRAV 985
Score = 38.5 bits (88), Expect = 0.001
Identities = 15/41 (36%), Positives = 20/41 (48%)
Query: 40 CTRESNPHCGSDGQTYGNKCAFCKAIVKSGGKISLKHPGKC 80
C ++ P CG DGQTY N C C + ++ GKC
Sbjct: 1036 CPKDLKPVCGDDGQTYNNPCMLCHENLIRQTNTHIRSTGKC 1076
Score = 38.1 bits (87), Expect = 0.002
Identities = 24/75 (32%), Positives = 36/75 (48%), Gaps = 4/75 (5%)
Query: 1 MKLSGMFLLLSLALFCFLTGVFSQGGQVDCGEFQ----DPKVYCTRESNPHCGSDGQTYG 56
MK++ + +LL LAL Q C EFQ + K++C ++ DG +
Sbjct: 1 MKIATVSVLLPLALCLIQDAASKNEDQEMCHEFQAFMKNGKLFCPQDKKFFQSLDGIMFI 60
Query: 57 NKCAFCKAIVKSGGK 71
NKCA CK I++ K
Sbjct: 61 NKCATCKMILEKEAK 75
Score = 38.1 bits (87), Expect = 0.002
Identities = 15/39 (38%), Positives = 26/39 (66%), Gaps = 4/39 (10%)
Query: 30 CGEFQDPK----VYCTRESNPHCGSDGQTYGNKCAFCKA 64
C ++Q+ ++CTRE++P G DG+ +GN C+ C+A
Sbjct: 297 CSQYQNQAKNGILFCTRENDPIRGPDGKMHGNLCSMCQA 335
Score = 38.1 bits (87), Expect = 0.002
Identities = 21/51 (41%), Positives = 30/51 (58%), Gaps = 4/51 (7%)
Query: 19 TGVFSQGGQVDCGEFQ----DPKVYCTRESNPHCGSDGQTYGNKCAFCKAI 65
TG S + C EF+ + K+ CTRE+NP G G+ + NKCA C++I
Sbjct: 838 TGERSNDKEDLCREFRSMQRNGKLICTRENNPVRGPYGKMHINKCAMCQSI 888
Score = 37.0 bits (84), Expect = 0.003
Identities = 16/46 (34%), Positives = 28/46 (60%), Gaps = 4/46 (8%)
Query: 30 CGEFQ----DPKVYCTRESNPHCGSDGQTYGNKCAFCKAIVKSGGK 71
C E++ + ++ CTRE++P G DG+ +GN C+ C+A + K
Sbjct: 567 CSEYRHYVRNGRLPCTRENDPIEGLDGKIHGNTCSMCEAFFQQEAK 612
>gi|14211875 esophagus cancer-related gene-2 [Homo sapiens]
Length = 85
Score = 50.1 bits (118), Expect = 4e-07
Identities = 31/85 (36%), Positives = 43/85 (50%), Gaps = 5/85 (5%)
Query: 1 MKLSGMFLLL-SLALFCFLTGVFSQGGQ-VDCGEFQDPKVY---CTRESNPHCGSDGQTY 55
MK++G LLL ++ FC + S + VDC ++ V C P CGSD TY
Sbjct: 1 MKITGGLLLLCTVVYFCSSSEAASLSPKKVDCSIYKKYPVVAIPCPITYLPVCGSDYITY 60
Query: 56 GNKCAFCKAIVKSGGKISLKHPGKC 80
GN+C C +KS G++ H G C
Sbjct: 61 GNECHLCTESLKSNGRVQFLHDGSC 85
>gi|45505132 serine protease inhibitor, Kazal type 1 precursor
[Homo sapiens]
Length = 79
Score = 48.9 bits (115), Expect = 9e-07
Identities = 30/82 (36%), Positives = 42/82 (51%), Gaps = 5/82 (6%)
Query: 1 MKLSGMFLLLSLALFCFL--TGVFSQGGQVDCGEFQDPKVYCTRESNPHCGSDGQTYGNK 58
MK++G+FLL +LAL TG S G + C + CT+ +P CG+DG TY N+
Sbjct: 1 MKVTGIFLLSALALLSLSGNTGADSLGREAKCYNELNG---CTKIYDPVCGTDGNTYPNE 57
Query: 59 CAFCKAIVKSGGKISLKHPGKC 80
C C K I ++ G C
Sbjct: 58 CVLCFENRKRQTSILIQKSGPC 79
>gi|10863911 serine protease inhibitor, Kazal type 2
(acrosin-trypsin inhibitor) [Homo sapiens]
Length = 84
Score = 48.5 bits (114), Expect = 1e-06
Identities = 30/86 (34%), Positives = 40/86 (46%), Gaps = 8/86 (9%)
Query: 1 MKLSGMFLLLSLALFCFLT------GVFSQGGQVDCGEFQDPKVYCTRESNPHCGSDGQT 54
M LS + L L L F G+FS+ +C +++ P C R NP CGSD T
Sbjct: 1 MALSVLRLALLLLAVTFAASLIPQFGLFSKYRTPNCSQYRLPG--CPRHFNPVCGSDMST 58
Query: 55 YGNKCAFCKAIVKSGGKISLKHPGKC 80
Y N+C C I + G I + G C
Sbjct: 59 YANECTLCMKIREGGHNIKIIRNGPC 84
>gi|19923632 Kazal-type serine peptidase inhibitor domain 1
precursor [Homo sapiens]
Length = 304
Score = 42.7 bits (99), Expect = 6e-05
Identities = 21/57 (36%), Positives = 29/57 (50%), Gaps = 2/57 (3%)
Query: 25 GGQVDCGEFQDPKVYCTRESNPHCGSDGQTYGNKCAFCKAI-VKSGGKISLKHPGKC 80
GG + GE +P C R +P CGSDG TY C +A + +++ HPG C
Sbjct: 113 GGDLSRGEVPEPLCAC-RSQSPLCGSDGHTYSQICRLQEAARARPDANLTVAHPGPC 168
>gi|7657453 serine peptidase inhibitor, Kazal type 4 [Homo
sapiens]
Length = 86
Score = 42.7 bits (99), Expect = 6e-05
Identities = 18/41 (43%), Positives = 25/41 (60%)
Query: 40 CTRESNPHCGSDGQTYGNKCAFCKAIVKSGGKISLKHPGKC 80
C++ SN CG+DG TY N+C C A +K+ I + GKC
Sbjct: 46 CSQMSNLVCGTDGLTYTNECQLCLARIKTKQDIQIMKDGKC 86
>gi|5453652 follistatin isoform FST317 precursor [Homo sapiens]
Length = 317
Score = 39.3 bits (90), Expect = 7e-04
Identities = 21/67 (31%), Positives = 33/67 (49%), Gaps = 14/67 (20%)
Query: 28 VDCG--------EFQDPKVYCTRESN------PHCGSDGQTYGNKCAFCKAIVKSGGKIS 73
VDCG + P+ C + + P CG DG+TY N+CA KA K ++
Sbjct: 98 VDCGPGKKCRMNKKNKPRCVCAPDCSNITWKGPVCGLDGKTYRNECALLKARCKEQPELE 157
Query: 74 LKHPGKC 80
+++ G+C
Sbjct: 158 VQYQGRC 164
Score = 38.1 bits (87), Expect = 0.002
Identities = 15/40 (37%), Positives = 22/40 (55%)
Query: 41 TRESNPHCGSDGQTYGNKCAFCKAIVKSGGKISLKHPGKC 80
++ P C SD TY ++CA +A SG + +KH G C
Sbjct: 277 SKSDEPVCASDNATYASECAMKEAACSSGVLLEVKHSGSC 316
Score = 34.3 bits (77), Expect = 0.022
Identities = 15/33 (45%), Positives = 18/33 (54%)
Query: 48 CGSDGQTYGNKCAFCKAIVKSGGKISLKHPGKC 80
CG+DG TY + C KA G I L + GKC
Sbjct: 207 CGNDGVTYSSACHLRKATCLLGRSIGLAYEGKC 239
>gi|7242222 follistatin isoform FST344 precursor [Homo sapiens]
Length = 344
Score = 39.3 bits (90), Expect = 7e-04
Identities = 21/67 (31%), Positives = 33/67 (49%), Gaps = 14/67 (20%)
Query: 28 VDCG--------EFQDPKVYCTRESN------PHCGSDGQTYGNKCAFCKAIVKSGGKIS 73
VDCG + P+ C + + P CG DG+TY N+CA KA K ++
Sbjct: 98 VDCGPGKKCRMNKKNKPRCVCAPDCSNITWKGPVCGLDGKTYRNECALLKARCKEQPELE 157
Query: 74 LKHPGKC 80
+++ G+C
Sbjct: 158 VQYQGRC 164
Score = 38.1 bits (87), Expect = 0.002
Identities = 15/40 (37%), Positives = 22/40 (55%)
Query: 41 TRESNPHCGSDGQTYGNKCAFCKAIVKSGGKISLKHPGKC 80
++ P C SD TY ++CA +A SG + +KH G C
Sbjct: 277 SKSDEPVCASDNATYASECAMKEAACSSGVLLEVKHSGSC 316
Score = 34.3 bits (77), Expect = 0.022
Identities = 15/33 (45%), Positives = 18/33 (54%)
Query: 48 CGSDGQTYGNKCAFCKAIVKSGGKISLKHPGKC 80
CG+DG TY + C KA G I L + GKC
Sbjct: 207 CGNDGVTYSSACHLRKATCLLGRSIGLAYEGKC 239
>gi|47679099 Kazal type serine protease inhibitor 5-like 2 [Homo
sapiens]
Length = 97
Score = 38.5 bits (88), Expect = 0.001
Identities = 17/41 (41%), Positives = 21/41 (51%)
Query: 40 CTRESNPHCGSDGQTYGNKCAFCKAIVKSGGKISLKHPGKC 80
C P CG++ TY N C C +KS G+I H GKC
Sbjct: 57 CPGLYQPICGTNFITYDNPCILCVESLKSHGRIRFYHDGKC 97
>gi|5901956 follistatin-like 1 precursor [Homo sapiens]
Length = 308
Score = 38.1 bits (87), Expect = 0.002
Identities = 17/50 (34%), Positives = 25/50 (50%), Gaps = 4/50 (8%)
Query: 35 DPKVYCTRESNPH----CGSDGQTYGNKCAFCKAIVKSGGKISLKHPGKC 80
+P C + PH CGS+G+TY N C + +G KI + + G C
Sbjct: 49 EPTCLCIEQCKPHKRPVCGSNGKTYLNHCELHRDACLTGSKIQVDYDGHC 98
>gi|190358524 follistatin-like 5 isoform c [Homo sapiens]
Length = 837
Score = 36.2 bits (82), Expect = 0.006
Identities = 19/55 (34%), Positives = 24/55 (43%), Gaps = 4/55 (7%)
Query: 26 GQVDCGEFQDPKVYCTRESNPHCGSDGQTYGNKCAFCKAIVKSGGKISLKHPGKC 80
GQ +C C R P CGSDG+ Y N C +A KI++ H C
Sbjct: 82 GQAECACMD----LCKRHYKPVCGSDGEFYENHCEVHRAACLKKQKITIVHNEDC 132
>gi|190358522 follistatin-like 5 isoform b [Homo sapiens]
Length = 846
Score = 36.2 bits (82), Expect = 0.006
Identities = 19/55 (34%), Positives = 24/55 (43%), Gaps = 4/55 (7%)
Query: 26 GQVDCGEFQDPKVYCTRESNPHCGSDGQTYGNKCAFCKAIVKSGGKISLKHPGKC 80
GQ +C C R P CGSDG+ Y N C +A KI++ H C
Sbjct: 82 GQAECACMD----LCKRHYKPVCGSDGEFYENHCEVHRAACLKKQKITIVHNEDC 132
>gi|190358520 follistatin-like 5 isoform a [Homo sapiens]
Length = 847
Score = 36.2 bits (82), Expect = 0.006
Identities = 19/55 (34%), Positives = 24/55 (43%), Gaps = 4/55 (7%)
Query: 26 GQVDCGEFQDPKVYCTRESNPHCGSDGQTYGNKCAFCKAIVKSGGKISLKHPGKC 80
GQ +C C R P CGSDG+ Y N C +A KI++ H C
Sbjct: 83 GQAECACMD----LCKRHYKPVCGSDGEFYENHCEVHRAACLKKQKITIVHNEDC 133
>gi|54873613 agrin [Homo sapiens]
Length = 2045
Score = 35.8 bits (81), Expect = 0.008
Identities = 15/33 (45%), Positives = 20/33 (60%)
Query: 48 CGSDGQTYGNKCAFCKAIVKSGGKISLKHPGKC 80
CGSDG TYGN+C + G +IS++ G C
Sbjct: 937 CGSDGVTYGNECQLKTIACRQGLQISIQSLGPC 969
Score = 34.3 bits (77), Expect = 0.022
Identities = 19/57 (33%), Positives = 25/57 (43%), Gaps = 4/57 (7%)
Query: 24 QGGQVDCGEFQDPKVYCTRESNPHCGSDGQTYGNKCAFCKAIVKSGGKISLKHPGKC 80
+ GQ C Q C+ +P CGSDG TYG+ C G +I + G C
Sbjct: 482 KNGQAACECLQA----CSSLYDPVCGSDGVTYGSACELEATACTLGREIQVARKGPC 534
Score = 32.3 bits (72), Expect = 0.084
Identities = 19/61 (31%), Positives = 23/61 (37%), Gaps = 6/61 (9%)
Query: 20 GVFSQGGQVDCGEFQDPKVYCTRESNPHCGSDGQTYGNKCAFCKAIVKSGGKISLKHPGK 79
G GQ C + P P CGSDG TYG+ C +A +I G
Sbjct: 610 GAVCSAGQCVCPRCEHPP------PGPVCGSDGVTYGSACELREAACLQQTQIEEARAGP 663
Query: 80 C 80
C
Sbjct: 664 C 664
Score = 31.6 bits (70), Expect = 0.14
Identities = 15/41 (36%), Positives = 18/41 (43%)
Query: 40 CTRESNPHCGSDGQTYGNKCAFCKAIVKSGGKISLKHPGKC 80
C P CGSD TY N+C +A +I L G C
Sbjct: 202 CPSVVAPVCGSDASTYSNECELQRAQCSQQRRIRLLSRGPC 242
Score = 31.2 bits (69), Expect = 0.19
Identities = 15/44 (34%), Positives = 20/44 (45%)
Query: 37 KVYCTRESNPHCGSDGQTYGNKCAFCKAIVKSGGKISLKHPGKC 80
+V C P C DG+TY + C +A + I KH G C
Sbjct: 418 RVTCDGAYRPVCAQDGRTYDSDCWRQQAECRQQRAIPSKHQGPC 461
Score = 30.4 bits (67), Expect = 0.32
Identities = 14/36 (38%), Positives = 19/36 (52%)
Query: 45 NPHCGSDGQTYGNKCAFCKAIVKSGGKISLKHPGKC 80
+P CGSDG TY +C KA +S + + G C
Sbjct: 715 SPVCGSDGVTYSTECELKKARCESQRGLYVAAQGAC 750
Score = 29.6 bits (65), Expect = 0.54
Identities = 13/41 (31%), Positives = 17/41 (41%)
Query: 40 CTRESNPHCGSDGQTYGNKCAFCKAIVKSGGKISLKHPGKC 80
C P CG DG TY N C ++ G + G+C
Sbjct: 349 CPARQAPVCGDDGVTYENDCVMGRSGAARGLLLQKVRSGQC 389
Score = 28.5 bits (62), Expect = 1.2
Identities = 10/20 (50%), Positives = 13/20 (65%)
Query: 40 CTRESNPHCGSDGQTYGNKC 59
C + P CGSDG TY ++C
Sbjct: 559 CVALAQPVCGSDGHTYPSEC 578
>gi|122937482 serine peptidase inhibitor, Kazal type 8 (putative)
[Homo sapiens]
Length = 97
Score = 35.0 bits (79), Expect = 0.013
Identities = 15/39 (38%), Positives = 21/39 (53%)
Query: 42 RESNPHCGSDGQTYGNKCAFCKAIVKSGGKISLKHPGKC 80
+ S P CGSD TY + C C I+ G I+ + G+C
Sbjct: 56 KPSEPICGSDQVTYSSDCHLCSKILFEGLNITKLYDGQC 94
>gi|12383051 transmembrane protein with EGF-like and two
follistatin-like domains 2 [Homo sapiens]
Length = 374
Score = 33.9 bits (76), Expect = 0.029
Identities = 14/41 (34%), Positives = 22/41 (53%)
Query: 40 CTRESNPHCGSDGQTYGNKCAFCKAIVKSGGKISLKHPGKC 80
C + P CGS+G++Y N+C +A K +I + G C
Sbjct: 95 CNNDYVPVCGSNGESYQNECYLRQAACKQQSEILVVSEGSC 135
Score = 33.1 bits (74), Expect = 0.049
Identities = 14/36 (38%), Positives = 20/36 (55%)
Query: 45 NPHCGSDGQTYGNKCAFCKAIVKSGGKISLKHPGKC 80
NP C SDG++Y N C +A + KI + G+C
Sbjct: 192 NPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRC 227
>gi|29568105 transmembrane protein with EGF-like and two
follistatin-like domains 1 [Homo sapiens]
Length = 380
Score = 33.1 bits (74), Expect = 0.049
Identities = 14/36 (38%), Positives = 19/36 (52%)
Query: 45 NPHCGSDGQTYGNKCAFCKAIVKSGGKISLKHPGKC 80
NP C SDG +Y N C +A +I ++H G C
Sbjct: 200 NPVCASDGSSYNNPCFVREASCIKQEQIDIRHLGHC 235
Score = 31.6 bits (70), Expect = 0.14
Identities = 15/41 (36%), Positives = 21/41 (51%)
Query: 40 CTRESNPHCGSDGQTYGNKCAFCKAIVKSGGKISLKHPGKC 80
C P CGS+G TY N+C +A K +I++ G C
Sbjct: 103 CHTNYIPVCGSNGDTYQNECFLRRAACKHQKEITVIARGPC 143
>gi|93141003 testican 3 isoform 1 [Homo sapiens]
Length = 433
Score = 32.3 bits (72), Expect = 0.084
Identities = 19/47 (40%), Positives = 23/47 (48%), Gaps = 4/47 (8%)
Query: 34 QDPKVYCTRESNPHCGSDGQTYGNKCAFCKAIVKSGGKISLKHPGKC 80
Q P VY +P CGSDG TY +C G +IS+K G C
Sbjct: 138 QCPVVY----PSPVCGSDGHTYSFQCKLEYQACVLGKQISVKCEGHC 180
>gi|93141001 testican 3 isoform 2 [Homo sapiens]
Length = 436
Score = 32.3 bits (72), Expect = 0.084
Identities = 19/47 (40%), Positives = 23/47 (48%), Gaps = 4/47 (8%)
Query: 34 QDPKVYCTRESNPHCGSDGQTYGNKCAFCKAIVKSGGKISLKHPGKC 80
Q P VY +P CGSDG TY +C G +IS+K G C
Sbjct: 141 QCPVVY----PSPVCGSDGHTYSFQCKLEYQACVLGKQISVKCEGHC 183
>gi|54792136 follistatin-like 4 [Homo sapiens]
Length = 842
Score = 32.3 bits (72), Expect = 0.084
Identities = 15/41 (36%), Positives = 20/41 (48%)
Query: 40 CTRESNPHCGSDGQTYGNKCAFCKAIVKSGGKISLKHPGKC 80
C P CGSDG+ Y N C +A G +I++ H C
Sbjct: 93 CRPSYVPVCGSDGRFYENHCKLHRAACLLGKRITVIHSKDC 133
>gi|118600977 C3 and PZP-like, alpha-2-macroglobulin domain containing
8 [Homo sapiens]
Length = 1932
Score = 32.3 bits (72), Expect = 0.084
Identities = 13/41 (31%), Positives = 18/41 (43%)
Query: 40 CTRESNPHCGSDGQTYGNKCAFCKAIVKSGGKISLKHPGKC 80
C + NP CGSDG Y + C +A + + P C
Sbjct: 1763 CGAQGNPVCGSDGVVYASACRLREAACRQAAPLEPAPPSCC 1803
>gi|92110017 serine PI Kazal type 5-like 3 [Homo sapiens]
Length = 94
Score = 32.3 bits (72), Expect = 0.084
Identities = 14/41 (34%), Positives = 21/41 (51%)
Query: 40 CTRESNPHCGSDGQTYGNKCAFCKAIVKSGGKISLKHPGKC 80
C + P C S+G T+ N+C FC + +I + GKC
Sbjct: 53 CPNVTAPVCASNGHTFQNECFFCVEQREFHYRIKFEKYGKC 93
>gi|148298722 zinc finger protein 185 [Homo sapiens]
Length = 689
Score = 31.2 bits (69), Expect = 0.19
Identities = 15/41 (36%), Positives = 21/41 (51%), Gaps = 3/41 (7%)
Query: 43 ESNPHCGS---DGQTYGNKCAFCKAIVKSGGKISLKHPGKC 80
E P CGS +T G C +C ++ KI+L+H G C
Sbjct: 610 EKKPPCGSTPYSERTTGGICTYCNREIRDCPKITLEHLGIC 650
>gi|22129776 HtrA serine peptidase 3 [Homo sapiens]
Length = 453
Score = 31.2 bits (69), Expect = 0.19
Identities = 26/80 (32%), Positives = 36/80 (45%), Gaps = 8/80 (10%)
Query: 9 LLSLALFCFLTGVFSQGGQVD--CGE-FQDPKVYCT-RESNPHCGSDGQTYGNKCAF--- 61
L + L C + GG +D CGE + + C R S+ CG+DG TY N CA
Sbjct: 47 LCNCCLVCAASEGEPCGGPLDSPCGESLECVRGLCRCRWSHAVCGTDGHTYANVCALQAA 106
Query: 62 -CKAIVKSGGKISLKHPGKC 80
+A+ SG + G C
Sbjct: 107 SRRALQLSGTPVRQLQKGAC 126
>gi|5031701 follistatin-like 3 glycoprotein precursor [Homo sapiens]
Length = 263
Score = 30.0 bits (66), Expect = 0.42
Identities = 12/33 (36%), Positives = 19/33 (57%)
Query: 48 CGSDGQTYGNKCAFCKAIVKSGGKISLKHPGKC 80
CGSDG TY ++C A + +S+ + G+C
Sbjct: 135 CGSDGATYRDECELRAARCRGHPDLSVMYRGRC 167
Score = 27.3 bits (59), Expect = 2.7
Identities = 11/33 (33%), Positives = 17/33 (51%)
Query: 48 CGSDGQTYGNKCAFCKAIVKSGGKISLKHPGKC 80
CG++ TY + C +A G I ++H G C
Sbjct: 211 CGNNNVTYISSCHMRQATCFLGRSIGVRHAGSC 243
>gi|78190498 secreted modular calcium-binding protein 1 isoform 1
[Homo sapiens]
Length = 435
Score = 30.0 bits (66), Expect = 0.42
Identities = 15/50 (30%), Positives = 30/50 (60%), Gaps = 4/50 (8%)
Query: 34 QDPK--VYCTR-ESNPHCGSDGQTYGNKCAFCKAIVKSGGKISLKHPGKC 80
+DP+ ++C+R + P C SDG++Y + C + +A + + + H G+C
Sbjct: 39 RDPQCNLHCSRTQPKPICASDGRSYESMCEYQRAKCRD-PTLGVVHRGRC 87
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.141 0.465
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 3,482,337
Number of Sequences: 37866
Number of extensions: 139218
Number of successful extensions: 511
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 39
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 410
Number of HSP's gapped (non-prelim): 101
length of query: 80
length of database: 18,247,518
effective HSP length: 52
effective length of query: 28
effective length of database: 16,278,486
effective search space: 455797608
effective search space used: 455797608
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 55 (25.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.