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Search of human proteins with 67782358
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|67782358 complement factor B preproprotein [Homo sapiens]
(764 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|67782358 complement factor B preproprotein [Homo sapiens] 1589 0.0
gi|14550407 complement component 2 isoform 1 preproprotein [Homo... 515 e-146
gi|225543438 complement component 2 isoform 2 preproprotein [Hom... 402 e-112
gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens] 94 4e-19
gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo sap... 94 6e-19
gi|205277354 CUB and Sushi multiple domains 3 isoform 3 [Homo sa... 94 6e-19
gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo sap... 94 6e-19
gi|148886654 polydom [Homo sapiens] 91 3e-18
gi|62912468 complement component 4 binding protein, beta chain i... 88 3e-17
gi|62912466 complement component 4 binding protein, beta chain i... 88 3e-17
gi|62912464 complement component 4 binding protein, beta chain i... 88 3e-17
gi|62912462 complement component 4 binding protein, beta chain i... 88 3e-17
gi|4502505 complement component 4 binding protein, beta chain is... 88 3e-17
gi|92110053 CUB and Sushi multiple domains 2 [Homo sapiens] 87 6e-17
gi|4506115 protein C [Homo sapiens] 80 9e-15
gi|110815798 ovochymase 1 [Homo sapiens] 79 2e-14
gi|4503625 coagulation factor X preproprotein [Homo sapiens] 78 4e-14
gi|145701030 transmembrane protease, serine 4 isoform 3 [Homo sa... 76 1e-13
gi|15451940 transmembrane protease, serine 4 isoform 1 [Homo sap... 76 1e-13
gi|148806900 epidermis-specific serine protease-like protein [Ho... 75 2e-13
gi|187960042 selectin E precursor [Homo sapiens] 74 7e-13
gi|54792123 complement component (3d/Epstein Barr virus) recepto... 74 7e-13
gi|4506153 prostasin preproprotein [Homo sapiens] 72 1e-12
gi|4502503 complement component 4 binding protein, alpha chain p... 69 1e-11
gi|157419154 selectin P precursor [Homo sapiens] 69 1e-11
gi|168693643 decay accelerating factor for complement isoform 2 ... 67 8e-11
gi|10835143 decay accelerating factor for complement isoform 1 p... 67 8e-11
gi|156938340 transmembrane tryptase preproprotein [Homo sapiens] 67 8e-11
gi|33186882 testis serine protease 2 [Homo sapiens] 66 1e-10
gi|7019563 testes-specific protease 50 [Homo sapiens] 66 1e-10
>gi|67782358 complement factor B preproprotein [Homo sapiens]
Length = 764
Score = 1589 bits (4115), Expect = 0.0
Identities = 764/764 (100%), Positives = 764/764 (100%)
Query: 1 MGSNLSPQLCLMPFILGLLSGGVTTTPWSLARPQGSCSLEGVEIKGGSFRLLQEGQALEY 60
MGSNLSPQLCLMPFILGLLSGGVTTTPWSLARPQGSCSLEGVEIKGGSFRLLQEGQALEY
Sbjct: 1 MGSNLSPQLCLMPFILGLLSGGVTTTPWSLARPQGSCSLEGVEIKGGSFRLLQEGQALEY 60
Query: 61 VCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEYWPRSPY 120
VCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEYWPRSPY
Sbjct: 61 VCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEYWPRSPY 120
Query: 121 YNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGTRKVGSQ 180
YNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGTRKVGSQ
Sbjct: 121 YNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGTRKVGSQ 180
Query: 181 YRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDSFMYDTPQEVAEAFLSSLTE 240
YRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDSFMYDTPQEVAEAFLSSLTE
Sbjct: 181 YRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDSFMYDTPQEVAEAFLSSLTE 240
Query: 241 TIEGVDAEDGHGPGEQQKRKIVLDPSGSMNIYLVLDGSDSIGASNFTGAKKCLVNLIEKV 300
TIEGVDAEDGHGPGEQQKRKIVLDPSGSMNIYLVLDGSDSIGASNFTGAKKCLVNLIEKV
Sbjct: 241 TIEGVDAEDGHGPGEQQKRKIVLDPSGSMNIYLVLDGSDSIGASNFTGAKKCLVNLIEKV 300
Query: 301 ASYGVKPRYGLVTYATYPKIWVKVSEADSSNADWVTKQLNEINYEDHKLKSGTNTKKALQ 360
ASYGVKPRYGLVTYATYPKIWVKVSEADSSNADWVTKQLNEINYEDHKLKSGTNTKKALQ
Sbjct: 301 ASYGVKPRYGLVTYATYPKIWVKVSEADSSNADWVTKQLNEINYEDHKLKSGTNTKKALQ 360
Query: 361 AVYSMMSWPDDVPPEGWNRTRHVIILMTDGLHNMGGDPITVIDEIRDLLYIGKDRKNPRE 420
AVYSMMSWPDDVPPEGWNRTRHVIILMTDGLHNMGGDPITVIDEIRDLLYIGKDRKNPRE
Sbjct: 361 AVYSMMSWPDDVPPEGWNRTRHVIILMTDGLHNMGGDPITVIDEIRDLLYIGKDRKNPRE 420
Query: 421 DYLDVYVFGVGPLVNQVNINALASKKDNEQHVFKVKDMENLEDVFYQMIDESQSLSLCGM 480
DYLDVYVFGVGPLVNQVNINALASKKDNEQHVFKVKDMENLEDVFYQMIDESQSLSLCGM
Sbjct: 421 DYLDVYVFGVGPLVNQVNINALASKKDNEQHVFKVKDMENLEDVFYQMIDESQSLSLCGM 480
Query: 481 VWEHRKGTDYHKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDKEHSIKVS 540
VWEHRKGTDYHKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDKEHSIKVS
Sbjct: 481 VWEHRKGTDYHKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDKEHSIKVS 540
Query: 541 VGGEKRDLEIEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCT 600
VGGEKRDLEIEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCT
Sbjct: 541 VGGEKRDLEIEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCT 600
Query: 601 EGTTRALRLPPTTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERDA 660
EGTTRALRLPPTTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERDA
Sbjct: 601 EGTTRALRLPPTTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERDA 660
Query: 661 QYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVISWG 720
QYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVISWG
Sbjct: 661 QYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVISWG 720
Query: 721 VVDVCKNQKRQKQVPAHARDFHINLFQVLPWLKEKLQDEDLGFL 764
VVDVCKNQKRQKQVPAHARDFHINLFQVLPWLKEKLQDEDLGFL
Sbjct: 721 VVDVCKNQKRQKQVPAHARDFHINLFQVLPWLKEKLQDEDLGFL 764
>gi|14550407 complement component 2 isoform 1 preproprotein [Homo
sapiens]
Length = 752
Score = 515 bits (1326), Expect = e-146
Identities = 297/751 (39%), Positives = 424/751 (56%), Gaps = 44/751 (5%)
Query: 30 LARPQGSCSLEGVEIKGGSFRLLQ---EGQALEYVCPSGFYPYPVQTRTCRSTGSWSTLK 86
LA SC + V I GG+F L G L Y CP G YP P +R C+S+G W T
Sbjct: 17 LADSAPSCP-QNVNISGGTFTLSHGWAPGSLLTYSCPQGLYPSPA-SRLCKSSGQWQTPG 74
Query: 87 TQDQKTVRKAECRAIHCPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQ 146
+++ KA C+ + CP P FENG Y PR Y V +SF C DG+ LRGS R C+
Sbjct: 75 AT--RSLSKAVCKPVRCPAPVSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCR 132
Query: 147 VNGRWSGQTAICDNGAGYCSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQ 206
NG W G+TA+CDNGAG+C NPGI +G + G ++ D V Y CS L L GS R CQ
Sbjct: 133 PNGMWDGETAVCDNGAGHCPNPGISLGAVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQ 192
Query: 207 EGGSWSGTEPSCQDSFMYDTPQEVAEAFLSSLTETIEGVDAEDGHGPGEQQKRKIVLDPS 266
G WSGTEP C+ + YD P++VA A +S + + + E RKI + S
Sbjct: 193 GNGVWSGTEPICRQPYSYDFPEDVAPALGTSFSHMLGATNPT--QKTKESLGRKIQIQRS 250
Query: 267 GSMNIYLVLDGSDSIGASNFTGAKKCLVNLIEKVASYGVKPRYGLVTYATYPKIWVKVSE 326
G +N+YL+LD S S+ ++F K+ +++++ S+ + ++T+A+ PK+ + V
Sbjct: 251 GHLNLYLLLDCSQSVSENDFLIFKESASLMVDRIFSFEINVSVAIITFASEPKVLMSVLN 310
Query: 327 ADSSNADWVTKQLNEINYEDHKLKSGTNTKKALQAVYSMMSWPD---DVPPEGWNRTRHV 383
+S + V L NY+DH+ +GTNT AL +VY MM+ + W RH
Sbjct: 311 DNSRDMTEVISSLENANYKDHENGTGTNTYAALNSVYLMMNNQMRLLGMETMAWQEIRHA 370
Query: 384 IILMTDGLHNMGGDPITVIDEIRDLLYIGKDRKNPREDYLDVYVFGVGPL-VNQVNINAL 442
IIL+TDG NMGG P T +D IR++L I + R DYLD+Y GVG L V+ +N L
Sbjct: 371 IILLTDGKSNMGGSPKTAVDHIREILNINQ----KRNDYLDIYAIGVGKLDVDWRELNEL 426
Query: 443 ASKKDNEQHVFKVKDMENLEDVFYQMIDESQ-SLSLCGMVWEHRKGTDYHKQPWQAKISV 501
SKKD E+H F ++D + L VF M+D S+ + ++CG+ +D + PW I
Sbjct: 427 GSKKDGERHAFILQDTKALHQVFEHMLDVSKLTDTICGVGNMSANASDQERTPWHVTIK- 485
Query: 502 IRPSKGHESCMGAVVSEYFVLTAAHCFTVDDKEHSI-KVSVGGEK----RDLEIEVVLFH 556
K E+C GA++S+ +VLTAAHCF D +HS+ +V+VG K ++ IE +
Sbjct: 486 ---PKSQETCRGALISDQWVLTAAHCFR-DGNDHSLWRVNVGDPKSQWGKEFLIEKAVIS 541
Query: 557 PNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEGTTRALRLPPTTTCQ 616
P +++ KK GI EFY D+AL+KL K+K RPICLPCT ALR P +TC+
Sbjct: 542 PGFDVFAKKNQGILEFYGDDIALLKLAQKVKMSTHARPICLPCTMEANLALRRPQGSTCR 601
Query: 617 QQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSC-ERDAQYAPGYDKVKDISEV 675
+ ELL Q + A FV+ KL + +K G + SC E +Q + + D+ EV
Sbjct: 602 DHENELLNKQSVPAHFVALNGSKL---NINLKMGVEWTSCAEVVSQEKTMFPNLTDVREV 658
Query: 676 VTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVISWGVVDVC-----KNQKR 730
VT +FLC+G D + C+G+SGG + + +R RF QVG++SWG+ + C KN ++
Sbjct: 659 VTDQFLCSG---TQEDESPCKGESGGAVFLERRFRFFQVGLVSWGLYNPCLGSADKNSRK 715
Query: 731 ---QKQVPAHARDFHINLFQVLPWLKEKLQD 758
+ +VP RDFHINLF++ PWL++ L D
Sbjct: 716 RAPRSKVPP-PRDFHINLFRMQPWLRQHLGD 745
>gi|225543438 complement component 2 isoform 2 preproprotein [Homo
sapiens]
Length = 620
Score = 402 bits (1032), Expect = e-112
Identities = 236/616 (38%), Positives = 348/616 (56%), Gaps = 37/616 (6%)
Query: 162 AGYCSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDS 221
AG+C NPGI +G + G ++ D V Y CS L L GS R CQ G WSGTEP C+
Sbjct: 16 AGHCPNPGISLGAVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPICRQP 75
Query: 222 FMYDTPQEVAEAFLSSLTETIEGVDAEDGHGPGEQQKRKIVLDPSGSMNIYLVLDGSDSI 281
+ YD P++VA A +S + + + E RKI + SG +N+YL+LD S S+
Sbjct: 76 YSYDFPEDVAPALGTSFSHMLGATNPT--QKTKESLGRKIQIQRSGHLNLYLLLDCSQSV 133
Query: 282 GASNFTGAKKCLVNLIEKVASYGVKPRYGLVTYATYPKIWVKVSEADSSNADWVTKQLNE 341
++F K+ +++++ S+ + ++T+A+ PK+ + V +S + V L
Sbjct: 134 SENDFLIFKESASLMVDRIFSFEINVSVAIITFASEPKVLMSVLNDNSRDMTEVISSLEN 193
Query: 342 INYEDHKLKSGTNTKKALQAVYSMMSWPD---DVPPEGWNRTRHVIILMTDGLHNMGGDP 398
NY+DH+ +GTNT AL +VY MM+ + W RH IIL+TDG NMGG P
Sbjct: 194 ANYKDHENGTGTNTYAALNSVYLMMNNQMRLLGMETMAWQEIRHAIILLTDGKSNMGGSP 253
Query: 399 ITVIDEIRDLLYIGKDRKNPREDYLDVYVFGVGPL-VNQVNINALASKKDNEQHVFKVKD 457
T +D IR++L I + R DYLD+Y GVG L V+ +N L SKKD E+H F ++D
Sbjct: 254 KTAVDHIREILNINQ----KRNDYLDIYAIGVGKLDVDWRELNELGSKKDGERHAFILQD 309
Query: 458 MENLEDVFYQMIDESQ-SLSLCGMVWEHRKGTDYHKQPWQAKISVIRPSKGHESCMGAVV 516
+ L VF M+D S+ + ++CG+ +D + PW I K E+C GA++
Sbjct: 310 TKALHQVFEHMLDVSKLTDTICGVGNMSANASDQERTPWHVTIK----PKSQETCRGALI 365
Query: 517 SEYFVLTAAHCFTVDDKEHSI-KVSVGGEK----RDLEIEVVLFHPNYNINGKKEAGIPE 571
S+ +VLTAAHCF D +HS+ +V+VG K ++ IE + P +++ KK GI E
Sbjct: 366 SDQWVLTAAHCFR-DGNDHSLWRVNVGDPKSQWGKEFLIEKAVISPGFDVFAKKNQGILE 424
Query: 572 FYDYDVALIKLKNKLKYGQTIRPICLPCTEGTTRALRLPPTTTCQQQKEELLPAQDIKAL 631
FY D+AL+KL K+K RPICLPCT ALR P +TC+ + ELL Q + A
Sbjct: 425 FYGDDIALLKLAQKVKMSTHARPICLPCTMEANLALRRPQGSTCRDHENELLNKQSVPAH 484
Query: 632 FVSEEEKKLTRKEVYIKNGDKKGSC-ERDAQYAPGYDKVKDISEVVTPRFLCTGGVSPYA 690
FV+ KL + +K G + SC E +Q + + D+ EVVT +FLC+G
Sbjct: 485 FVALNGSKL---NINLKMGVEWTSCAEVVSQEKTMFPNLTDVREVVTDQFLCSG---TQE 538
Query: 691 DPNTCRGDSGGPLIVHKRSRFIQVGVISWGVVDVC-----KNQKR---QKQVPAHARDFH 742
D + C+G+SGG + + +R RF QVG++SWG+ + C KN ++ + +VP RDFH
Sbjct: 539 DESPCKGESGGAVFLERRFRFFQVGLVSWGLYNPCLGSADKNSRKRAPRSKVPP-PRDFH 597
Query: 743 INLFQVLPWLKEKLQD 758
INLF++ PWL++ L D
Sbjct: 598 INLFRMQPWLRQHLGD 613
Score = 38.9 bits (89), Expect = 0.018
Identities = 22/64 (34%), Positives = 29/64 (45%), Gaps = 4/64 (6%)
Query: 102 HCPRPHDFENGEYWPRSPY-YNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDN 160
HCP P G R+ + + D++ + C L GS+ R CQ NG WSG IC
Sbjct: 18 HCPNP-GISLGAV--RTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPICRQ 74
Query: 161 GAGY 164
Y
Sbjct: 75 PYSY 78
>gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens]
Length = 3565
Score = 94.4 bits (233), Expect = 4e-19
Identities = 54/167 (32%), Positives = 76/167 (45%), Gaps = 15/167 (8%)
Query: 56 QALEYVCPSGFYPYPVQTRTCRST--GSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGE 113
+ + Y C G+ V + T R T G W+ K C+A+ CP+P +NG
Sbjct: 3058 KTVSYQCNPGYVMEAVTSATIRCTKDGRWNP---------SKPVCKAVLCPQPPPVQNGT 3108
Query: 114 YWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIG 173
+ IS+ C DGY L SA +C+ G W G+ C +C +PGIP
Sbjct: 3109 V--EGSDFRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCL--PVFCGDPGIPAE 3164
Query: 174 TRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQD 220
R G + + V + C L GS RR CQ G+WSG +P+C D
Sbjct: 3165 GRLSGKSFTYKSEVFFQCKSPFILVGSSRRVCQADGTWSGIQPTCID 3211
Score = 89.4 bits (220), Expect = 1e-17
Identities = 49/166 (29%), Positives = 70/166 (42%), Gaps = 12/166 (7%)
Query: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEY 114
G ++ Y C GFY TC + G W +C AI C P N
Sbjct: 2821 GMSILYHCKKGFYLLGSSALTCMANGLWDR---------SLPKCLAISCGHPGVPANAVL 2871
Query: 115 WPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICD-NGAGYCSNPGIPIG 173
+ + + C +L G+ R CQ + WSG C N G+C +PG P
Sbjct: 2872 --TGELFTYGAVVHYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFCGDPGTPAH 2929
Query: 174 TRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
++G ++ + + + C G LRGS RTC GSWSG +P C+
Sbjct: 2930 GSRLGDDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVCE 2975
Score = 87.8 bits (216), Expect = 3e-17
Identities = 49/165 (29%), Positives = 74/165 (44%), Gaps = 13/165 (7%)
Query: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEY 114
G + C +G+ R C + G WS +T+ C A HC P NG
Sbjct: 2642 GATAIFTCNTGYTLVGSHVRECLANGLWSGSETR---------CLAGHCGSPDPIVNGHI 2692
Query: 115 WPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGT 174
++ D + + C G+ L G++ R C + +WSGQT +C C +PG P
Sbjct: 2693 --SGDGFSYRDTVVYQCNPGFRLVGTSVRICLQDHKWSGQTPVCVPIT--CGHPGNPAHG 2748
Query: 175 RKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
GS++ L D V + C+ G L+G R C+ G WS P+C+
Sbjct: 2749 FTNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTCR 2793
Score = 73.9 bits (180), Expect = 5e-13
Identities = 39/93 (41%), Positives = 46/93 (49%), Gaps = 3/93 (3%)
Query: 127 ISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGTRKVGSQYRL-ED 185
+ F C G+ LRGS RTC +NG WSG +C+ A C NPG P V S L
Sbjct: 2943 LRFSCEMGHQLRGSPERTCLLNGSWSGLQPVCE--AVSCGNPGTPTNGMIVSSDGILFSS 3000
Query: 186 SVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSC 218
SV Y C G G R C G+W+GT P C
Sbjct: 3001 SVIYACWEGYKTSGLMTRHCTANGTWTGTAPDC 3033
Score = 70.9 bits (172), Expect = 4e-12
Identities = 53/184 (28%), Positives = 73/184 (39%), Gaps = 16/184 (8%)
Query: 60 YVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEYWPRSP 119
Y C G+ + TR C + G+W T +C I C P NG +
Sbjct: 3004 YACWEGYKTSGLMTRHCTANGTW---------TGTAPDCTIISCGDPGTLANGIQFGTDF 3054
Query: 120 YYNVSDEISFHCYDGYTLRG--SANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGTRKV 177
+N + +S+ C GY + SA C +GRW+ +C A C P
Sbjct: 3055 TFNKT--VSYQCNPGYVMEAVTSATIRCTKDGRWNPSKPVCK--AVLCPQPPPVQNGTVE 3110
Query: 178 GSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDSFMYDTPQEVAEAFLSS 237
GS +R S++Y C G L S +C+ G W G P C F D P AE LS
Sbjct: 3111 GSDFRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPVFCGD-PGIPAEGRLSG 3169
Query: 238 LTET 241
+ T
Sbjct: 3170 KSFT 3173
Score = 68.9 bits (167), Expect = 2e-11
Identities = 44/164 (26%), Positives = 66/164 (40%), Gaps = 14/164 (8%)
Query: 58 LEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEYWPR 117
L + C G RTC GSWS L+ C A+ C P NG
Sbjct: 2943 LRFSCEMGHQLRGSPERTCLLNGSWSGLQPV---------CEAVSCGNPGTPTNGMI-VS 2992
Query: 118 SPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGTRKV 177
S S + + C++GY G R C NG W+G C + C +PG +
Sbjct: 2993 SDGILFSSSVIYACWEGYKTSGLMTRHCTANGTWTGTAPDCTIIS--CGDPGTLANGIQF 3050
Query: 178 GSQYRLEDSVTYHCSRGLTLRGSQRRT--CQEGGSWSGTEPSCQ 219
G+ + +V+Y C+ G + T C + G W+ ++P C+
Sbjct: 3051 GTDFTFNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSKPVCK 3094
Score = 67.0 bits (162), Expect = 6e-11
Identities = 46/146 (31%), Positives = 65/146 (44%), Gaps = 12/146 (8%)
Query: 82 WSTLKTQDQKTVRKAECRAIHCPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSA 141
WST +K K A +C H +NG R+ V ++ + C GY + G +
Sbjct: 2413 WSTDHATSKKGF-KIRYAAPYCSLTHPLKNGGILNRTAGA-VGSKVHYFCKPGYRMVGHS 2470
Query: 142 NRTCQVNG----RWSGQTAICDNGAGYCSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTL 197
N TC+ N +W T +C A C P P G+++ L+ V Y C G L
Sbjct: 2471 NATCRRNPLGMYQWDSLTPLCQ--AVSCGIPESPGNGSFTGNEFTLDSKVVYECHEGFKL 2528
Query: 198 RGSQRRT--CQEGGSWS--GTEPSCQ 219
SQ+ T CQE G WS G P+C+
Sbjct: 2529 ESSQQATAVCQEDGLWSNKGKPPTCK 2554
Score = 62.0 bits (149), Expect = 2e-09
Identities = 53/196 (27%), Positives = 75/196 (38%), Gaps = 24/196 (12%)
Query: 44 IKGGSFRLLQEGQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHC 103
+ G SF E + + C S F R C++ G+WS ++ C
Sbjct: 3167 LSGKSFTYKSE---VFFQCKSPFILVGSSRRVCQADGTWSGIQPTCIDPAHNT------C 3217
Query: 104 PRPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAG 163
P P G S Y V + F C GY ++GS RTC N WSG C A
Sbjct: 3218 PDPGTPHFG-IQNSSRGYEVGSTVFFRCRKGYHIQGSTTRTCLANLTWSGIQTECIPHA- 3275
Query: 164 YCSNPGIPIGTRKVGSQYRLED------SVTYHCSRGLTLR-GSQRRTCQEGGSWSGTEP 216
C P P + R D ++ Y C G L GS+ RTC+ W+G P
Sbjct: 3276 -CRQPETP-----AHADVRAIDLPTFGYTLVYTCHPGFFLAGGSEHRTCKADMKWTGKSP 3329
Query: 217 SCQDSFMYDTPQEVAE 232
C+ + + + V +
Sbjct: 3330 VCKSKGVREVNETVTK 3345
Score = 54.3 bits (129), Expect = 4e-07
Identities = 23/63 (36%), Positives = 35/63 (55%)
Query: 163 GYCSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDSF 222
G C +PGIP ++ GS + D++T+ C L G + TCQ+ WSG +PSC S
Sbjct: 526 GGCGDPGIPAYGKRTGSSFLHGDTLTFECPAAFELVGERVITCQQNNQWSGNKPSCVFSC 585
Query: 223 MYD 225
++
Sbjct: 586 FFN 588
Score = 53.9 bits (128), Expect = 5e-07
Identities = 42/164 (25%), Positives = 56/164 (34%), Gaps = 12/164 (7%)
Query: 60 YVCPSGFYPYPVQ--TRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPH-DFENGEYWP 116
Y C GF Q T C+ G WS + C+ + CP W
Sbjct: 2520 YECHEGFKLESSQQATAVCQEDGLWSNKG-------KPPTCKPVACPSIEAQLSEHVIWR 2572
Query: 117 --RSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGT 174
++ C GY L G CQ NG W+ C + P
Sbjct: 2573 LVSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQANGTWNIGDERPSCRVISCGSLSFPPNG 2632
Query: 175 RKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSC 218
K+G+ + + C+ G TL GS R C G WSG+E C
Sbjct: 2633 NKIGTLTVYGATAIFTCNTGYTLVGSHVRECLANGLWSGSETRC 2676
Score = 50.1 bits (118), Expect = 8e-06
Identities = 26/63 (41%), Positives = 37/63 (58%), Gaps = 4/63 (6%)
Query: 161 GAGYCSNPGIPIGTRKVGSQYRLEDSVTYHCSRG-LTLRGSQRRTC--QEGG-SWSGTEP 216
G C +PGIPI R+ G ++ L SV++HC G + +GS+ TC Q+G WS T P
Sbjct: 694 GQNECHDPGIPINGRRFGDRFLLGSSVSFHCDDGFVKTQGSESITCILQDGNVVWSSTVP 753
Query: 217 SCQ 219
C+
Sbjct: 754 RCE 756
Score = 49.3 bits (116), Expect = 1e-05
Identities = 41/142 (28%), Positives = 63/142 (44%), Gaps = 13/142 (9%)
Query: 165 CSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGS--WSGTEP----SC 218
C +PG+P +R++G + + DS+T+ C G L G+ + TC GG WS P C
Sbjct: 1046 CDDPGVPAFSRRIGFHFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLPRCVAEC 1105
Query: 219 QDSFMYDTPQEVAEAFLSSLT---ETIEGVDAEDGHGPGEQQKRKIVLDPSGSMNIYLVL 275
S + ++ F S+ E I ++ E G G + R L ++ +Y
Sbjct: 1106 GASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGI-HLRTRSFQLFEGDTLKVY--- 1161
Query: 276 DGSDSIGASNFTGAKKCLVNLI 297
DG DS T K L+ LI
Sbjct: 1162 DGKDSSSRPLGTFTKNELLGLI 1183
Score = 47.8 bits (112), Expect = 4e-05
Identities = 27/65 (41%), Positives = 33/65 (50%), Gaps = 4/65 (6%)
Query: 102 HCPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQ--VNGRWSGQTAICD 159
+CP P F+NG Y S Y +V +SF CY GY L G TCQ +N W+ CD
Sbjct: 2087 NCPDPPPFQNG-YMINSDY-SVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRCD 2144
Query: 160 NGAGY 164
GY
Sbjct: 2145 APCGY 2149
Score = 45.4 bits (106), Expect = 2e-04
Identities = 17/54 (31%), Positives = 27/54 (50%)
Query: 165 CSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSC 218
C +PGIP+ + G + + +VT+ C G TL + C+ W+ PSC
Sbjct: 874 CLDPGIPVNGHRHGGDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQWNHALPSC 927
Score = 43.1 bits (100), Expect = 0.001
Identities = 18/60 (30%), Positives = 29/60 (48%), Gaps = 2/60 (3%)
Query: 161 GAGYCSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEG--GSWSGTEPSC 218
G C P +P + K+G +Y + D +++ C G TL+G +C G W+ P C
Sbjct: 1912 GLAACQEPALPSNSIKIGDRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSPLC 1971
Score = 39.7 bits (91), Expect = 0.011
Identities = 21/60 (35%), Positives = 31/60 (51%), Gaps = 5/60 (8%)
Query: 165 CSNPGIPIGTRKVGSQY-RLEDSVTYHCSRGLTLRGSQRRTCQEG----GSWSGTEPSCQ 219
C +PGIP R+ GS + R+ +V + C L+GS+ TCQ +WS P C+
Sbjct: 349 CPDPGIPENGRRAGSDFSRVGANVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPICR 408
Score = 39.3 bits (90), Expect = 0.014
Identities = 18/60 (30%), Positives = 29/60 (48%), Gaps = 3/60 (5%)
Query: 162 AGYCSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGS---WSGTEPSC 218
A C++PG+P + G D+VT+ C G L+G + TC + + W P+C
Sbjct: 1389 AATCNDPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTC 1448
Score = 37.4 bits (85), Expect = 0.053
Identities = 18/58 (31%), Positives = 27/58 (46%), Gaps = 4/58 (6%)
Query: 165 CSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGG----SWSGTEPSC 218
C +PG + +VG+ ++L ++TY C G + TC G SW PSC
Sbjct: 1565 CFDPGNIMNGTRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSC 1622
Score = 36.6 bits (83), Expect = 0.090
Identities = 22/60 (36%), Positives = 26/60 (43%), Gaps = 5/60 (8%)
Query: 103 CPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQ----VNGRWSGQTAIC 158
CP P ENG S + V + F C D Y L+GS + TCQ WS IC
Sbjct: 349 CPDPGIPENGRR-AGSDFSRVGANVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPIC 407
Score = 36.6 bits (83), Expect = 0.090
Identities = 25/86 (29%), Positives = 35/86 (40%), Gaps = 4/86 (4%)
Query: 137 LRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLT 196
LR SA G A+ CS+ P R++GS++ V + C+ G
Sbjct: 1714 LRFSAKSGASARGFHFVYQAVPRTSDTQCSSVPEPRYGRRIGSEFSAGSIVRFECNPGYL 1773
Query: 197 LRGSQRRTCQEG----GSWSGTEPSC 218
L+GS CQ W+ T PSC
Sbjct: 1774 LQGSTALHCQSVPNALAQWNDTIPSC 1799
Score = 35.4 bits (80), Expect = 0.20
Identities = 19/54 (35%), Positives = 26/54 (48%), Gaps = 4/54 (7%)
Query: 120 YYNVSDEISFHCYDGYTLRGSANRTCQVNGR--WSGQTAIC--DNGAGYCSNPG 169
++ V D ++F C+ GY L G+ TC GR WS C + GA N G
Sbjct: 1061 HFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLPRCVAECGASVKGNEG 1114
Score = 35.4 bits (80), Expect = 0.20
Identities = 19/57 (33%), Positives = 26/57 (45%), Gaps = 3/57 (5%)
Query: 165 CSNPGIPIGTRKVGSQYRLEDSVT-YHCSRGLTLRGSQRRTCQEGGS--WSGTEPSC 218
C +PGIP ++ + D+V Y C+ G + GS TC G W PSC
Sbjct: 1218 CEDPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTCLSGDRRVWDKPLPSC 1274
Score = 34.3 bits (77), Expect = 0.45
Identities = 18/59 (30%), Positives = 25/59 (42%), Gaps = 4/59 (6%)
Query: 165 CSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTC----QEGGSWSGTEPSCQ 219
C NPG + G+++ + D + Y C G L G TC G SW P C+
Sbjct: 145 CGNPGEILKGVLHGTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPFCR 203
Score = 33.9 bits (76), Expect = 0.58
Identities = 20/54 (37%), Positives = 26/54 (48%), Gaps = 3/54 (5%)
Query: 121 YNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGT 174
+N+ D+I + C GY L G A TC V+ G A D A +C G GT
Sbjct: 161 FNIGDKIRYSCLPGYILEGHAILTCIVS---PGNGASWDFPAPFCRAEGACGGT 211
Score = 33.9 bits (76), Expect = 0.58
Identities = 15/40 (37%), Positives = 24/40 (60%), Gaps = 2/40 (5%)
Query: 121 YNVSDEISFHCYDGYTLRGSANRTCQVN--GRWSGQTAIC 158
Y V+D +SF C GYTL+G ++ +C RW+ + +C
Sbjct: 1932 YMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSPLC 1971
Score = 32.0 bits (71), Expect = 2.2
Identities = 30/124 (24%), Positives = 47/124 (37%), Gaps = 16/124 (12%)
Query: 56 QALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEYW 115
QA +++ +G + Y + T T S S L + T+ C P G++
Sbjct: 833 QAPQFLISTGNFMYLLFT-TDNSRSSIGFLIHYESVTLESDSCLDPGIPVNGHRHGGDFG 891
Query: 116 PRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICD--------NGAGYCSN 167
RS ++F C GYTL C+ N +W+ CD +G +
Sbjct: 892 IRST-------VTFSCDPGYTLSDDEPLVCERNHQWNHALPSCDALCGGYIQGKSGTVLS 944
Query: 168 PGIP 171
PG P
Sbjct: 945 PGFP 948
Score = 31.6 bits (70), Expect = 2.9
Identities = 13/34 (38%), Positives = 17/34 (50%)
Query: 125 DEISFHCYDGYTLRGSANRTCQVNGRWSGQTAIC 158
D ++F C + L G TCQ N +WSG C
Sbjct: 548 DTLTFECPAAFELVGERVITCQQNNQWSGNKPSC 581
Score = 31.6 bits (70), Expect = 2.9
Identities = 18/81 (22%), Positives = 32/81 (39%), Gaps = 12/81 (14%)
Query: 103 CPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNG--RWSGQTAICD- 159
C P E + + D + + C+ GYTL G+ TC+++ ++ G C+
Sbjct: 2259 CQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCEA 2318
Query: 160 ---------NGAGYCSNPGIP 171
+G +PG P
Sbjct: 2319 QCPANEVRTGSSGVILSPGYP 2339
Score = 30.8 bits (68), Expect = 4.9
Identities = 22/67 (32%), Positives = 28/67 (41%), Gaps = 5/67 (7%)
Query: 100 AIHCPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTC-QVNGR--WSGQTA 156
A C P +NG + S D ++F C GY L+G A TC Q+N R W
Sbjct: 1389 AATCNDPGMPQNGTRYGDSR--EAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPP 1446
Query: 157 ICDNGAG 163
C G
Sbjct: 1447 TCIAACG 1453
>gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo sapiens]
Length = 3667
Score = 93.6 bits (231), Expect = 6e-19
Identities = 54/166 (32%), Positives = 76/166 (45%), Gaps = 15/166 (9%)
Query: 55 GQALEYVCPSGFYPY--PVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENG 112
GQ + Y+C G+ + RTC G+WS + CRA+ CP P NG
Sbjct: 3152 GQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPT---------CRAVTCPTPPQISNG 3202
Query: 113 EYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPI 172
++ IS+ C GY L A TC NG WSG+ C +C +PGIP
Sbjct: 3203 RL--EGTNFDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCL--PKFCGDPGIPA 3258
Query: 173 GTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSC 218
++ G + + V++ C+ L GS R CQ G+WSG+ P C
Sbjct: 3259 QGKREGKSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHC 3304
Score = 93.2 bits (230), Expect = 8e-19
Identities = 54/178 (30%), Positives = 77/178 (43%), Gaps = 15/178 (8%)
Query: 43 EIKGGSFRLLQEGQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIH 102
+I+ G+F G + Y C G++ + C+ G W EC I
Sbjct: 2907 KIEHGNFTY---GTVVFYDCNPGYFLFGSSVLICQPNGQWDK---------PLPECIMID 2954
Query: 103 CPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGA 162
C P N Y + + C +L G ++RTCQ+NG WSG C A
Sbjct: 2955 CGHPGVPPNAVL--SGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDA 3012
Query: 163 -GYCSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
G C +PG P + S +R + +V Y C G L GS+ RTC GSW+G +P C+
Sbjct: 3013 TGTCGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPECK 3070
Score = 89.0 bits (219), Expect = 2e-17
Identities = 52/165 (31%), Positives = 73/165 (44%), Gaps = 13/165 (7%)
Query: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEY 114
G + C GF R C S+G WS +T+ C A HC P NG+
Sbjct: 2738 GSTAIFTCDLGFMLVGSAVRECLSSGLWSESETR---------CLAGHCGIPELIVNGQV 2788
Query: 115 WPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGT 174
+ Y D + + C G+ L GS+ R CQ + WSGQ C + C +PG PI
Sbjct: 2789 IGEN--YGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVS--CGHPGSPIYG 2844
Query: 175 RKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
R G+ + D VT+ C+ G ++G + CQ WS P C+
Sbjct: 2845 RTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCK 2889
Score = 82.8 bits (203), Expect = 1e-15
Identities = 52/166 (31%), Positives = 76/166 (45%), Gaps = 13/166 (7%)
Query: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEY 114
G ++ Y+C G+ TC G+WS Q C C P G+
Sbjct: 3212 GFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQ---------CLPKFCGDPGIPAQGKR 3262
Query: 115 WPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAIC-DNGAGYCSNPGIPI- 172
+S Y E+SF C + L GS+ R CQ +G WSG + C + C NPG+P
Sbjct: 3263 EGKSFIYQ--SEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRH 3320
Query: 173 GTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSC 218
G++ +++ V +HC +G L+GS RTC +WSG +P C
Sbjct: 3321 GSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPEC 3366
Score = 77.8 bits (190), Expect = 4e-14
Identities = 61/194 (31%), Positives = 76/194 (39%), Gaps = 19/194 (9%)
Query: 37 CSLEGVEIKGGSFRL--LQEGQALEYVCPSGFYPYPVQTRTCRSTGSWS-TLKTQDQKTV 93
C G G FR+ ++ Y C G+ R C + G+WS TL
Sbjct: 3074 CGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPN------ 3127
Query: 94 RKAECRAIHCPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYT--LRGSANRTCQVNGRW 151
C I C P NG + Y V +S+ C GYT L GS RTC +NG W
Sbjct: 3128 ----CTIISCGDPGIPANGLRYGDD--YVVGQNVSYMCQPGYTMELNGSRIRTCTINGTW 3181
Query: 152 SGQTAICDNGAGYCSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSW 211
SG C A C P R G+ + S++Y CS G L TC G+W
Sbjct: 3182 SGVMPTCR--AVTCPTPPQISNGRLEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGTW 3239
Query: 212 SGTEPSCQDSFMYD 225
SG P C F D
Sbjct: 3240 SGEVPQCLPKFCGD 3253
Score = 74.7 bits (182), Expect = 3e-13
Identities = 48/159 (30%), Positives = 67/159 (42%), Gaps = 11/159 (6%)
Query: 60 YVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEYWPRSP 119
+ C G++ + C G+WS + C+ I C NG
Sbjct: 2683 FSCDPGYHGLGPASIECLPNGTWSWRN-------ERPYCQIISCGELPTPPNGNKIGTQT 2735
Query: 120 YYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGTRKVGS 179
Y + F C G+ L GSA R C +G WS C AG+C P + + + +G
Sbjct: 2736 SYGST--AIFTCDLGFMLVGSAVRECLSSGLWSESETRCL--AGHCGIPELIVNGQVIGE 2791
Query: 180 QYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSC 218
Y D+V Y C+ G L GS R CQ+ +WSG PSC
Sbjct: 2792 NYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSC 2830
Score = 74.3 bits (181), Expect = 4e-13
Identities = 54/177 (30%), Positives = 69/177 (38%), Gaps = 35/177 (19%)
Query: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEY 114
G + Y C +RTC+ G WS + HC G+
Sbjct: 2974 GSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQP--------------HCSGDATGTCGD- 3018
Query: 115 WPRSPYYNVSDEISFH--------CYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCS 166
P +P + E +F C GY L GS RTC NG W+G+ C A C
Sbjct: 3019 -PGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPECK--AVQCG 3075
Query: 167 NPGIPIGTRKVGSQYRLE-----DSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSC 218
NPG T G +R++ SV Y C G L G R C G+WSGT P+C
Sbjct: 3076 NPG----TTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNC 3128
Score = 66.6 bits (161), Expect = 8e-11
Identities = 44/163 (26%), Positives = 62/163 (38%), Gaps = 17/163 (10%)
Query: 60 YVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEYWPRSP 119
Y C GF R C+ +WS + C + C P G
Sbjct: 2801 YQCNPGFRLIGSSVRICQQDHNWSG---------QLPSCVPVSCGHPGSPIYGRTSGNG- 2850
Query: 120 YYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGTRKVG- 178
+N +D ++F C GY ++G CQ N +WS +C CS+PGIP +++
Sbjct: 2851 -FNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCK--VVNCSDPGIPANSKRESK 2907
Query: 179 ---SQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSC 218
+ V Y C+ G L GS CQ G W P C
Sbjct: 2908 IEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPEC 2950
Score = 63.5 bits (153), Expect = 7e-10
Identities = 57/218 (26%), Positives = 89/218 (40%), Gaps = 29/218 (13%)
Query: 13 PFILGLLSGGVTTTPWSLARPQ---GSCSLEGVEIKGGSFRLLQEGQALEYVCPSGF--- 66
P +L + G WS PQ C G+ +G +EG++ Y F
Sbjct: 3228 PAVLTCVGNGT----WSGEVPQCLPKFCGDPGIPAQGK-----REGKSFIYQSEVSFSCN 3278
Query: 67 YPYPV---QTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEYWPRSPYYNV 123
+P+ + TR C++ G+WS + + + C PR H +N + + V
Sbjct: 3279 FPFILVGSSTRICQADGTWSGSSPHCIEPTQTS-CENPGVPR-HGSQNNTFG-----FQV 3331
Query: 124 SDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGTRKVGSQYRL 183
+ FHC G+ L+GS RTC + WSG C + C P P VG
Sbjct: 3332 GSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHS--CKQPETPAHANVVGMDLPS 3389
Query: 184 ED-SVTYHCSRGLTLRG-SQRRTCQEGGSWSGTEPSCQ 219
++ Y C G L G ++ R C+ +W+G P C+
Sbjct: 3390 HGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPICE 3427
Score = 43.9 bits (102), Expect = 6e-04
Identities = 20/56 (35%), Positives = 29/56 (51%), Gaps = 2/56 (3%)
Query: 165 CSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGS--WSGTEPSC 218
C +PGIP ++G + + D++T+ CS G L G+ C GG WS P C
Sbjct: 1142 CEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRC 1197
Score = 43.9 bits (102), Expect = 6e-04
Identities = 44/171 (25%), Positives = 64/171 (37%), Gaps = 35/171 (20%)
Query: 10 CLMPFIL-----------GLLSGGVTTTPWSLARPQGSCSLEGVEIKGGSFRLL--QEGQ 56
C PFIL G SG ++P + Q SC GV G Q G
Sbjct: 3277 CNFPFILVGSSTRICQADGTWSG---SSPHCIEPTQTSCENPGVPRHGSQNNTFGFQVGS 3333
Query: 57 ALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRP----HDFENG 112
+++ C G TRTC +WS ++ EC C +P H G
Sbjct: 3334 VVQFHCKKGHLLQGSTTRTCLPDLTWSGIQP---------ECIPHSCKQPETPAHANVVG 3384
Query: 113 EYWPRSPYYNVSDEISFHCYDGYTLRGSA-NRTCQVNGRWSGQTAICDNGA 162
P Y + + C G+ L G +R C+ + W+G+ IC+ G+
Sbjct: 3385 MDLPSHGY-----TLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPICEAGS 3430
Score = 42.0 bits (97), Expect = 0.002
Identities = 22/62 (35%), Positives = 33/62 (53%), Gaps = 4/62 (6%)
Query: 161 GAGYCSNPGIPIGTRKVGSQYRLEDSVTYHCSRG-LTLRGSQRRTC--QEGG-SWSGTEP 216
G C +PGIPI R+ G ++L S++ C G + +G++ TC +G WSG P
Sbjct: 790 GHNECPDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIP 849
Query: 217 SC 218
C
Sbjct: 850 KC 851
Score = 41.6 bits (96), Expect = 0.003
Identities = 20/58 (34%), Positives = 29/58 (50%), Gaps = 4/58 (6%)
Query: 165 CSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGG----SWSGTEPSC 218
C +PG + ++G Y+L +VTY+C G L+G TC G W+ PSC
Sbjct: 1661 CFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSC 1718
Score = 41.2 bits (95), Expect = 0.004
Identities = 16/54 (29%), Positives = 28/54 (51%)
Query: 165 CSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSC 218
C +PGIP+ R+ G + + +V++ C G L + C++ WS P+C
Sbjct: 970 CLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTC 1023
Score = 40.4 bits (93), Expect = 0.006
Identities = 18/59 (30%), Positives = 30/59 (50%), Gaps = 4/59 (6%)
Query: 165 CSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQE----GGSWSGTEPSCQ 219
C +PG P +++GS + L +V + C L+G++ TCQ +WS P C+
Sbjct: 446 CPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCK 504
Score = 40.4 bits (93), Expect = 0.006
Identities = 17/54 (31%), Positives = 24/54 (44%)
Query: 165 CSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSC 218
C +PG P+ + G + D + + C G L G + CQE WS P C
Sbjct: 624 CGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPIC 677
Score = 40.0 bits (92), Expect = 0.008
Identities = 32/125 (25%), Positives = 49/125 (39%), Gaps = 16/125 (12%)
Query: 109 FENGEYWPRSPYYNVSDEIS--FHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGY-- 164
F W +Y+ D + Y G T+ N T N + Q+ I + AG+
Sbjct: 1944 FATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSN-NLYLNFQSDISVSAAGFHL 2002
Query: 165 ---------CSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEG--GSWSG 213
C P P K+G +Y + D V++ C +G +L+G TC G W+
Sbjct: 2003 EYTAIGLDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNY 2062
Query: 214 TEPSC 218
P C
Sbjct: 2063 PIPIC 2067
Score = 38.5 bits (88), Expect = 0.024
Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 16/81 (19%)
Query: 103 CPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTC--QVNGRWSGQTAICD- 159
CP P F NG + V ISF C+ GYTL G++ TC V+ W+ C+
Sbjct: 2184 CPDPRPFRNGFVIGND--FTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEA 2241
Query: 160 ---------NGAGYCSNPGIP 171
NG Y +PG P
Sbjct: 2242 LCGGNITAMNGTIY--SPGYP 2260
Score = 37.0 bits (84), Expect = 0.069
Identities = 17/57 (29%), Positives = 27/57 (47%), Gaps = 3/57 (5%)
Query: 165 CSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTC---QEGGSWSGTEPSC 218
C +PG+P+ + G D+V + C G L+G +R TC + W + P C
Sbjct: 1488 CRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVC 1544
Score = 35.8 bits (81), Expect = 0.15
Identities = 18/59 (30%), Positives = 26/59 (44%), Gaps = 4/59 (6%)
Query: 165 CSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTC----QEGGSWSGTEPSCQ 219
C NPG+P G+++ + D + Y C G L G + TC SW P C+
Sbjct: 138 CGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICR 196
Score = 34.3 bits (77), Expect = 0.45
Identities = 18/60 (30%), Positives = 29/60 (48%), Gaps = 6/60 (10%)
Query: 103 CPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQ----VNGRWSGQTAIC 158
CP P + ENG+ +++ + F C + Y L+G+ + TCQ V WS +C
Sbjct: 446 CPDPGEPENGKRIGSD--FSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVC 503
Score = 34.3 bits (77), Expect = 0.45
Identities = 21/81 (25%), Positives = 31/81 (38%), Gaps = 12/81 (14%)
Query: 103 CPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGR--WSGQTAICD- 159
C P N E + + D I + C G+TL G+A TC++ R G +C
Sbjct: 2355 CQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQV 2414
Query: 160 ---------NGAGYCSNPGIP 171
+ G +PG P
Sbjct: 2415 LCPANELRLDSTGVILSPGYP 2435
Score = 33.5 bits (75), Expect = 0.76
Identities = 16/51 (31%), Positives = 22/51 (43%), Gaps = 8/51 (15%)
Query: 116 PRSPYYNVS--------DEISFHCYDGYTLRGSANRTCQVNGRWSGQTAIC 158
P +P Y + D + F C G+ L G + CQ N +WS IC
Sbjct: 627 PGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPIC 677
Score = 33.5 bits (75), Expect = 0.76
Identities = 18/54 (33%), Positives = 26/54 (48%), Gaps = 4/54 (7%)
Query: 121 YNVSDEISFHCYDGYTLRGSANRTCQVNGR--WSGQTAIC--DNGAGYCSNPGI 170
+ + D ++F C GY L G++ C GR WS C + GA +N GI
Sbjct: 1158 FGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAECGASATNNEGI 1211
Score = 32.0 bits (71), Expect = 2.2
Identities = 16/58 (27%), Positives = 29/58 (50%), Gaps = 4/58 (6%)
Query: 165 CSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQ----EGGSWSGTEPSC 218
CS+ P R++G+++ + SV + C+ G L GS C+ W+ + P+C
Sbjct: 1838 CSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTC 1895
Score = 30.8 bits (68), Expect = 4.9
Identities = 13/45 (28%), Positives = 24/45 (53%), Gaps = 2/45 (4%)
Query: 177 VGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGS--WSGTEPSCQ 219
+G+ + + ++++ C G TL G+ TC G S W+ P C+
Sbjct: 2196 IGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCE 2240
Score = 30.0 bits (66), Expect = 8.4
Identities = 16/59 (27%), Positives = 23/59 (38%), Gaps = 8/59 (13%)
Query: 121 YNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICD--------NGAGYCSNPGIP 171
+++ +SF C GY L C+ N WS CD +G +PG P
Sbjct: 986 FSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYP 1044
>gi|205277354 CUB and Sushi multiple domains 3 isoform 3 [Homo
sapiens]
Length = 3538
Score = 93.6 bits (231), Expect = 6e-19
Identities = 54/166 (32%), Positives = 76/166 (45%), Gaps = 15/166 (9%)
Query: 55 GQALEYVCPSGFYPY--PVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENG 112
GQ + Y+C G+ + RTC G+WS + CRA+ CP P NG
Sbjct: 3023 GQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPT---------CRAVTCPTPPQISNG 3073
Query: 113 EYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPI 172
++ IS+ C GY L A TC NG WSG+ C +C +PGIP
Sbjct: 3074 RL--EGTNFDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCL--PKFCGDPGIPA 3129
Query: 173 GTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSC 218
++ G + + V++ C+ L GS R CQ G+WSG+ P C
Sbjct: 3130 QGKREGKSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHC 3175
Score = 93.2 bits (230), Expect = 8e-19
Identities = 54/178 (30%), Positives = 77/178 (43%), Gaps = 15/178 (8%)
Query: 43 EIKGGSFRLLQEGQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIH 102
+I+ G+F G + Y C G++ + C+ G W EC I
Sbjct: 2778 KIEHGNFTY---GTVVFYDCNPGYFLFGSSVLICQPNGQWDK---------PLPECIMID 2825
Query: 103 CPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGA 162
C P N Y + + C +L G ++RTCQ+NG WSG C A
Sbjct: 2826 CGHPGVPPNAVL--SGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDA 2883
Query: 163 -GYCSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
G C +PG P + S +R + +V Y C G L GS+ RTC GSW+G +P C+
Sbjct: 2884 TGTCGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPECK 2941
Score = 89.0 bits (219), Expect = 2e-17
Identities = 52/165 (31%), Positives = 73/165 (44%), Gaps = 13/165 (7%)
Query: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEY 114
G + C GF R C S+G WS +T+ C A HC P NG+
Sbjct: 2609 GSTAIFTCDLGFMLVGSAVRECLSSGLWSESETR---------CLAGHCGIPELIVNGQV 2659
Query: 115 WPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGT 174
+ Y D + + C G+ L GS+ R CQ + WSGQ C + C +PG PI
Sbjct: 2660 IGEN--YGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVS--CGHPGSPIYG 2715
Query: 175 RKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
R G+ + D VT+ C+ G ++G + CQ WS P C+
Sbjct: 2716 RTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCK 2760
Score = 82.8 bits (203), Expect = 1e-15
Identities = 52/166 (31%), Positives = 76/166 (45%), Gaps = 13/166 (7%)
Query: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEY 114
G ++ Y+C G+ TC G+WS Q C C P G+
Sbjct: 3083 GFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQ---------CLPKFCGDPGIPAQGKR 3133
Query: 115 WPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAIC-DNGAGYCSNPGIPI- 172
+S Y E+SF C + L GS+ R CQ +G WSG + C + C NPG+P
Sbjct: 3134 EGKSFIYQ--SEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRH 3191
Query: 173 GTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSC 218
G++ +++ V +HC +G L+GS RTC +WSG +P C
Sbjct: 3192 GSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPEC 3237
Score = 80.1 bits (196), Expect = 7e-15
Identities = 59/186 (31%), Positives = 77/186 (41%), Gaps = 14/186 (7%)
Query: 36 SCSLEGVEIKGGSFRL-LQEGQALEYVCPSGFY--PYPVQTRTCRSTGSWSTLKTQDQKT 92
SC + GG G + Y C G+ + T C+S G+WS KT
Sbjct: 2527 SCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSN----HNKT 2582
Query: 93 VRKAECRAIHCPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWS 152
R C I C NG Y + F C G+ L GSA R C +G WS
Sbjct: 2583 PR---CVVISCGELPTPPNGNKIGTQTSYGST--AIFTCDLGFMLVGSAVRECLSSGLWS 2637
Query: 153 GQTAICDNGAGYCSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWS 212
C AG+C P + + + +G Y D+V Y C+ G L GS R CQ+ +WS
Sbjct: 2638 ESETRCL--AGHCGIPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWS 2695
Query: 213 GTEPSC 218
G PSC
Sbjct: 2696 GQLPSC 2701
Score = 77.8 bits (190), Expect = 4e-14
Identities = 61/194 (31%), Positives = 76/194 (39%), Gaps = 19/194 (9%)
Query: 37 CSLEGVEIKGGSFRL--LQEGQALEYVCPSGFYPYPVQTRTCRSTGSWS-TLKTQDQKTV 93
C G G FR+ ++ Y C G+ R C + G+WS TL
Sbjct: 2945 CGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPN------ 2998
Query: 94 RKAECRAIHCPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYT--LRGSANRTCQVNGRW 151
C I C P NG + Y V +S+ C GYT L GS RTC +NG W
Sbjct: 2999 ----CTIISCGDPGIPANGLRYGDD--YVVGQNVSYMCQPGYTMELNGSRIRTCTINGTW 3052
Query: 152 SGQTAICDNGAGYCSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSW 211
SG C A C P R G+ + S++Y CS G L TC G+W
Sbjct: 3053 SGVMPTCR--AVTCPTPPQISNGRLEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGTW 3110
Query: 212 SGTEPSCQDSFMYD 225
SG P C F D
Sbjct: 3111 SGEVPQCLPKFCGD 3124
Score = 74.3 bits (181), Expect = 4e-13
Identities = 54/177 (30%), Positives = 69/177 (38%), Gaps = 35/177 (19%)
Query: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEY 114
G + Y C +RTC+ G WS + HC G+
Sbjct: 2845 GSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQP--------------HCSGDATGTCGD- 2889
Query: 115 WPRSPYYNVSDEISFH--------CYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCS 166
P +P + E +F C GY L GS RTC NG W+G+ C A C
Sbjct: 2890 -PGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPECK--AVQCG 2946
Query: 167 NPGIPIGTRKVGSQYRLE-----DSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSC 218
NPG T G +R++ SV Y C G L G R C G+WSGT P+C
Sbjct: 2947 NPG----TTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNC 2999
Score = 66.6 bits (161), Expect = 8e-11
Identities = 44/163 (26%), Positives = 62/163 (38%), Gaps = 17/163 (10%)
Query: 60 YVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEYWPRSP 119
Y C GF R C+ +WS + C + C P G
Sbjct: 2672 YQCNPGFRLIGSSVRICQQDHNWSG---------QLPSCVPVSCGHPGSPIYGRTSGNG- 2721
Query: 120 YYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGTRKVG- 178
+N +D ++F C GY ++G CQ N +WS +C CS+PGIP +++
Sbjct: 2722 -FNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCK--VVNCSDPGIPANSKRESK 2778
Query: 179 ---SQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSC 218
+ V Y C+ G L GS CQ G W P C
Sbjct: 2779 IEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPEC 2821
Score = 63.5 bits (153), Expect = 7e-10
Identities = 57/218 (26%), Positives = 89/218 (40%), Gaps = 29/218 (13%)
Query: 13 PFILGLLSGGVTTTPWSLARPQ---GSCSLEGVEIKGGSFRLLQEGQALEYVCPSGF--- 66
P +L + G WS PQ C G+ +G +EG++ Y F
Sbjct: 3099 PAVLTCVGNGT----WSGEVPQCLPKFCGDPGIPAQGK-----REGKSFIYQSEVSFSCN 3149
Query: 67 YPYPV---QTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEYWPRSPYYNV 123
+P+ + TR C++ G+WS + + + C PR H +N + + V
Sbjct: 3150 FPFILVGSSTRICQADGTWSGSSPHCIEPTQTS-CENPGVPR-HGSQNNTFG-----FQV 3202
Query: 124 SDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGTRKVGSQYRL 183
+ FHC G+ L+GS RTC + WSG C + C P P VG
Sbjct: 3203 GSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHS--CKQPETPAHANVVGMDLPS 3260
Query: 184 ED-SVTYHCSRGLTLRG-SQRRTCQEGGSWSGTEPSCQ 219
++ Y C G L G ++ R C+ +W+G P C+
Sbjct: 3261 HGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPICE 3298
Score = 43.9 bits (102), Expect = 6e-04
Identities = 20/56 (35%), Positives = 29/56 (51%), Gaps = 2/56 (3%)
Query: 165 CSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGS--WSGTEPSC 218
C +PGIP ++G + + D++T+ CS G L G+ C GG WS P C
Sbjct: 1078 CEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRC 1133
Score = 43.9 bits (102), Expect = 6e-04
Identities = 44/171 (25%), Positives = 64/171 (37%), Gaps = 35/171 (20%)
Query: 10 CLMPFIL-----------GLLSGGVTTTPWSLARPQGSCSLEGVEIKGGSFRLL--QEGQ 56
C PFIL G SG ++P + Q SC GV G Q G
Sbjct: 3148 CNFPFILVGSSTRICQADGTWSG---SSPHCIEPTQTSCENPGVPRHGSQNNTFGFQVGS 3204
Query: 57 ALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRP----HDFENG 112
+++ C G TRTC +WS ++ EC C +P H G
Sbjct: 3205 VVQFHCKKGHLLQGSTTRTCLPDLTWSGIQP---------ECIPHSCKQPETPAHANVVG 3255
Query: 113 EYWPRSPYYNVSDEISFHCYDGYTLRGSA-NRTCQVNGRWSGQTAICDNGA 162
P Y + + C G+ L G +R C+ + W+G+ IC+ G+
Sbjct: 3256 MDLPSHGY-----TLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPICEAGS 3301
Score = 42.0 bits (97), Expect = 0.002
Identities = 22/62 (35%), Positives = 33/62 (53%), Gaps = 4/62 (6%)
Query: 161 GAGYCSNPGIPIGTRKVGSQYRLEDSVTYHCSRG-LTLRGSQRRTC--QEGG-SWSGTEP 216
G C +PGIPI R+ G ++L S++ C G + +G++ TC +G WSG P
Sbjct: 726 GHNECPDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIP 785
Query: 217 SC 218
C
Sbjct: 786 KC 787
Score = 41.6 bits (96), Expect = 0.003
Identities = 20/58 (34%), Positives = 29/58 (50%), Gaps = 4/58 (6%)
Query: 165 CSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGG----SWSGTEPSC 218
C +PG + ++G Y+L +VTY+C G L+G TC G W+ PSC
Sbjct: 1597 CFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSC 1654
Score = 41.2 bits (95), Expect = 0.004
Identities = 16/54 (29%), Positives = 28/54 (51%)
Query: 165 CSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSC 218
C +PGIP+ R+ G + + +V++ C G L + C++ WS P+C
Sbjct: 906 CLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTC 959
Score = 40.4 bits (93), Expect = 0.006
Identities = 18/59 (30%), Positives = 30/59 (50%), Gaps = 4/59 (6%)
Query: 165 CSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQE----GGSWSGTEPSCQ 219
C +PG P +++GS + L +V + C L+G++ TCQ +WS P C+
Sbjct: 382 CPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCK 440
Score = 40.4 bits (93), Expect = 0.006
Identities = 17/54 (31%), Positives = 24/54 (44%)
Query: 165 CSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSC 218
C +PG P+ + G + D + + C G L G + CQE WS P C
Sbjct: 560 CGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPIC 613
Score = 40.0 bits (92), Expect = 0.008
Identities = 32/125 (25%), Positives = 49/125 (39%), Gaps = 16/125 (12%)
Query: 109 FENGEYWPRSPYYNVSDEIS--FHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGY-- 164
F W +Y+ D + Y G T+ N T N + Q+ I + AG+
Sbjct: 1880 FATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSN-NLYLNFQSDISVSAAGFHL 1938
Query: 165 ---------CSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEG--GSWSG 213
C P P K+G +Y + D V++ C +G +L+G TC G W+
Sbjct: 1939 EYTAIGLDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNY 1998
Query: 214 TEPSC 218
P C
Sbjct: 1999 PIPIC 2003
Score = 38.5 bits (88), Expect = 0.024
Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 16/81 (19%)
Query: 103 CPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTC--QVNGRWSGQTAICD- 159
CP P F NG + V ISF C+ GYTL G++ TC V+ W+ C+
Sbjct: 2120 CPDPRPFRNGFVIGND--FTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEA 2177
Query: 160 ---------NGAGYCSNPGIP 171
NG Y +PG P
Sbjct: 2178 LCGGNITAMNGTIY--SPGYP 2196
Score = 37.0 bits (84), Expect = 0.069
Identities = 17/57 (29%), Positives = 27/57 (47%), Gaps = 3/57 (5%)
Query: 165 CSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTC---QEGGSWSGTEPSC 218
C +PG+P+ + G D+V + C G L+G +R TC + W + P C
Sbjct: 1424 CRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVC 1480
Score = 35.8 bits (81), Expect = 0.15
Identities = 18/59 (30%), Positives = 26/59 (44%), Gaps = 4/59 (6%)
Query: 165 CSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTC----QEGGSWSGTEPSCQ 219
C NPG+P G+++ + D + Y C G L G + TC SW P C+
Sbjct: 178 CGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICR 236
Score = 34.3 bits (77), Expect = 0.45
Identities = 18/60 (30%), Positives = 29/60 (48%), Gaps = 6/60 (10%)
Query: 103 CPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQ----VNGRWSGQTAIC 158
CP P + ENG+ +++ + F C + Y L+G+ + TCQ V WS +C
Sbjct: 382 CPDPGEPENGKRIGSD--FSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVC 439
Score = 34.3 bits (77), Expect = 0.45
Identities = 21/81 (25%), Positives = 31/81 (38%), Gaps = 12/81 (14%)
Query: 103 CPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGR--WSGQTAICD- 159
C P N E + + D I + C G+TL G+A TC++ R G +C
Sbjct: 2291 CQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQV 2350
Query: 160 ---------NGAGYCSNPGIP 171
+ G +PG P
Sbjct: 2351 LCPANELRLDSTGVILSPGYP 2371
Score = 33.5 bits (75), Expect = 0.76
Identities = 16/51 (31%), Positives = 22/51 (43%), Gaps = 8/51 (15%)
Query: 116 PRSPYYNVS--------DEISFHCYDGYTLRGSANRTCQVNGRWSGQTAIC 158
P +P Y + D + F C G+ L G + CQ N +WS IC
Sbjct: 563 PGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPIC 613
Score = 33.5 bits (75), Expect = 0.76
Identities = 18/54 (33%), Positives = 26/54 (48%), Gaps = 4/54 (7%)
Query: 121 YNVSDEISFHCYDGYTLRGSANRTCQVNGR--WSGQTAIC--DNGAGYCSNPGI 170
+ + D ++F C GY L G++ C GR WS C + GA +N GI
Sbjct: 1094 FGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAECGASATNNEGI 1147
Score = 32.0 bits (71), Expect = 2.2
Identities = 16/58 (27%), Positives = 29/58 (50%), Gaps = 4/58 (6%)
Query: 165 CSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQ----EGGSWSGTEPSC 218
CS+ P R++G+++ + SV + C+ G L GS C+ W+ + P+C
Sbjct: 1774 CSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTC 1831
Score = 30.8 bits (68), Expect = 4.9
Identities = 13/45 (28%), Positives = 24/45 (53%), Gaps = 2/45 (4%)
Query: 177 VGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGS--WSGTEPSCQ 219
+G+ + + ++++ C G TL G+ TC G S W+ P C+
Sbjct: 2132 IGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCE 2176
Score = 30.0 bits (66), Expect = 8.4
Identities = 16/59 (27%), Positives = 23/59 (38%), Gaps = 8/59 (13%)
Query: 121 YNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICD--------NGAGYCSNPGIP 171
+++ +SF C GY L C+ N WS CD +G +PG P
Sbjct: 922 FSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYP 980
>gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo sapiens]
Length = 3707
Score = 93.6 bits (231), Expect = 6e-19
Identities = 54/166 (32%), Positives = 76/166 (45%), Gaps = 15/166 (9%)
Query: 55 GQALEYVCPSGFYPY--PVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENG 112
GQ + Y+C G+ + RTC G+WS + CRA+ CP P NG
Sbjct: 3192 GQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPT---------CRAVTCPTPPQISNG 3242
Query: 113 EYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPI 172
++ IS+ C GY L A TC NG WSG+ C +C +PGIP
Sbjct: 3243 RL--EGTNFDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCL--PKFCGDPGIPA 3298
Query: 173 GTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSC 218
++ G + + V++ C+ L GS R CQ G+WSG+ P C
Sbjct: 3299 QGKREGKSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHC 3344
Score = 93.2 bits (230), Expect = 8e-19
Identities = 54/178 (30%), Positives = 77/178 (43%), Gaps = 15/178 (8%)
Query: 43 EIKGGSFRLLQEGQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIH 102
+I+ G+F G + Y C G++ + C+ G W EC I
Sbjct: 2947 KIEHGNFTY---GTVVFYDCNPGYFLFGSSVLICQPNGQWDK---------PLPECIMID 2994
Query: 103 CPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGA 162
C P N Y + + C +L G ++RTCQ+NG WSG C A
Sbjct: 2995 CGHPGVPPNAVL--SGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDA 3052
Query: 163 -GYCSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
G C +PG P + S +R + +V Y C G L GS+ RTC GSW+G +P C+
Sbjct: 3053 TGTCGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPECK 3110
Score = 89.0 bits (219), Expect = 2e-17
Identities = 52/165 (31%), Positives = 73/165 (44%), Gaps = 13/165 (7%)
Query: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEY 114
G + C GF R C S+G WS +T+ C A HC P NG+
Sbjct: 2778 GSTAIFTCDLGFMLVGSAVRECLSSGLWSESETR---------CLAGHCGIPELIVNGQV 2828
Query: 115 WPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGT 174
+ Y D + + C G+ L GS+ R CQ + WSGQ C + C +PG PI
Sbjct: 2829 IGEN--YGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVS--CGHPGSPIYG 2884
Query: 175 RKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
R G+ + D VT+ C+ G ++G + CQ WS P C+
Sbjct: 2885 RTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCK 2929
Score = 82.8 bits (203), Expect = 1e-15
Identities = 52/166 (31%), Positives = 76/166 (45%), Gaps = 13/166 (7%)
Query: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEY 114
G ++ Y+C G+ TC G+WS Q C C P G+
Sbjct: 3252 GFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQ---------CLPKFCGDPGIPAQGKR 3302
Query: 115 WPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAIC-DNGAGYCSNPGIPI- 172
+S Y E+SF C + L GS+ R CQ +G WSG + C + C NPG+P
Sbjct: 3303 EGKSFIYQ--SEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRH 3360
Query: 173 GTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSC 218
G++ +++ V +HC +G L+GS RTC +WSG +P C
Sbjct: 3361 GSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPEC 3406
Score = 77.8 bits (190), Expect = 4e-14
Identities = 61/194 (31%), Positives = 76/194 (39%), Gaps = 19/194 (9%)
Query: 37 CSLEGVEIKGGSFRL--LQEGQALEYVCPSGFYPYPVQTRTCRSTGSWS-TLKTQDQKTV 93
C G G FR+ ++ Y C G+ R C + G+WS TL
Sbjct: 3114 CGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPN------ 3167
Query: 94 RKAECRAIHCPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYT--LRGSANRTCQVNGRW 151
C I C P NG + Y V +S+ C GYT L GS RTC +NG W
Sbjct: 3168 ----CTIISCGDPGIPANGLRYGDD--YVVGQNVSYMCQPGYTMELNGSRIRTCTINGTW 3221
Query: 152 SGQTAICDNGAGYCSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSW 211
SG C A C P R G+ + S++Y CS G L TC G+W
Sbjct: 3222 SGVMPTCR--AVTCPTPPQISNGRLEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGTW 3279
Query: 212 SGTEPSCQDSFMYD 225
SG P C F D
Sbjct: 3280 SGEVPQCLPKFCGD 3293
Score = 74.7 bits (182), Expect = 3e-13
Identities = 48/159 (30%), Positives = 67/159 (42%), Gaps = 11/159 (6%)
Query: 60 YVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEYWPRSP 119
+ C G++ + C G+WS + C+ I C NG
Sbjct: 2723 FSCDPGYHGLGPASIECLPNGTWSWRN-------ERPYCQIISCGELPTPPNGNKIGTQT 2775
Query: 120 YYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGTRKVGS 179
Y + F C G+ L GSA R C +G WS C AG+C P + + + +G
Sbjct: 2776 SYGST--AIFTCDLGFMLVGSAVRECLSSGLWSESETRCL--AGHCGIPELIVNGQVIGE 2831
Query: 180 QYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSC 218
Y D+V Y C+ G L GS R CQ+ +WSG PSC
Sbjct: 2832 NYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSC 2870
Score = 74.3 bits (181), Expect = 4e-13
Identities = 54/177 (30%), Positives = 69/177 (38%), Gaps = 35/177 (19%)
Query: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEY 114
G + Y C +RTC+ G WS + HC G+
Sbjct: 3014 GSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQP--------------HCSGDATGTCGD- 3058
Query: 115 WPRSPYYNVSDEISFH--------CYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCS 166
P +P + E +F C GY L GS RTC NG W+G+ C A C
Sbjct: 3059 -PGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPECK--AVQCG 3115
Query: 167 NPGIPIGTRKVGSQYRLE-----DSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSC 218
NPG T G +R++ SV Y C G L G R C G+WSGT P+C
Sbjct: 3116 NPG----TTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNC 3168
Score = 66.6 bits (161), Expect = 8e-11
Identities = 44/163 (26%), Positives = 62/163 (38%), Gaps = 17/163 (10%)
Query: 60 YVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEYWPRSP 119
Y C GF R C+ +WS + C + C P G
Sbjct: 2841 YQCNPGFRLIGSSVRICQQDHNWSG---------QLPSCVPVSCGHPGSPIYGRTSGNG- 2890
Query: 120 YYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGTRKVG- 178
+N +D ++F C GY ++G CQ N +WS +C CS+PGIP +++
Sbjct: 2891 -FNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCK--VVNCSDPGIPANSKRESK 2947
Query: 179 ---SQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSC 218
+ V Y C+ G L GS CQ G W P C
Sbjct: 2948 IEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPEC 2990
Score = 63.5 bits (153), Expect = 7e-10
Identities = 57/218 (26%), Positives = 89/218 (40%), Gaps = 29/218 (13%)
Query: 13 PFILGLLSGGVTTTPWSLARPQ---GSCSLEGVEIKGGSFRLLQEGQALEYVCPSGF--- 66
P +L + G WS PQ C G+ +G +EG++ Y F
Sbjct: 3268 PAVLTCVGNGT----WSGEVPQCLPKFCGDPGIPAQGK-----REGKSFIYQSEVSFSCN 3318
Query: 67 YPYPV---QTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEYWPRSPYYNV 123
+P+ + TR C++ G+WS + + + C PR H +N + + V
Sbjct: 3319 FPFILVGSSTRICQADGTWSGSSPHCIEPTQTS-CENPGVPR-HGSQNNTFG-----FQV 3371
Query: 124 SDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGTRKVGSQYRL 183
+ FHC G+ L+GS RTC + WSG C + C P P VG
Sbjct: 3372 GSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHS--CKQPETPAHANVVGMDLPS 3429
Query: 184 ED-SVTYHCSRGLTLRG-SQRRTCQEGGSWSGTEPSCQ 219
++ Y C G L G ++ R C+ +W+G P C+
Sbjct: 3430 HGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPICE 3467
Score = 43.9 bits (102), Expect = 6e-04
Identities = 20/56 (35%), Positives = 29/56 (51%), Gaps = 2/56 (3%)
Query: 165 CSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGS--WSGTEPSC 218
C +PGIP ++G + + D++T+ CS G L G+ C GG WS P C
Sbjct: 1182 CEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRC 1237
Score = 43.9 bits (102), Expect = 6e-04
Identities = 44/171 (25%), Positives = 64/171 (37%), Gaps = 35/171 (20%)
Query: 10 CLMPFIL-----------GLLSGGVTTTPWSLARPQGSCSLEGVEIKGGSFRLL--QEGQ 56
C PFIL G SG ++P + Q SC GV G Q G
Sbjct: 3317 CNFPFILVGSSTRICQADGTWSG---SSPHCIEPTQTSCENPGVPRHGSQNNTFGFQVGS 3373
Query: 57 ALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRP----HDFENG 112
+++ C G TRTC +WS ++ EC C +P H G
Sbjct: 3374 VVQFHCKKGHLLQGSTTRTCLPDLTWSGIQP---------ECIPHSCKQPETPAHANVVG 3424
Query: 113 EYWPRSPYYNVSDEISFHCYDGYTLRGSA-NRTCQVNGRWSGQTAICDNGA 162
P Y + + C G+ L G +R C+ + W+G+ IC+ G+
Sbjct: 3425 MDLPSHGY-----TLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPICEAGS 3470
Score = 42.0 bits (97), Expect = 0.002
Identities = 22/62 (35%), Positives = 33/62 (53%), Gaps = 4/62 (6%)
Query: 161 GAGYCSNPGIPIGTRKVGSQYRLEDSVTYHCSRG-LTLRGSQRRTC--QEGG-SWSGTEP 216
G C +PGIPI R+ G ++L S++ C G + +G++ TC +G WSG P
Sbjct: 830 GHNECPDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIP 889
Query: 217 SC 218
C
Sbjct: 890 KC 891
Score = 41.6 bits (96), Expect = 0.003
Identities = 20/58 (34%), Positives = 29/58 (50%), Gaps = 4/58 (6%)
Query: 165 CSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGG----SWSGTEPSC 218
C +PG + ++G Y+L +VTY+C G L+G TC G W+ PSC
Sbjct: 1701 CFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSC 1758
Score = 41.2 bits (95), Expect = 0.004
Identities = 16/54 (29%), Positives = 28/54 (51%)
Query: 165 CSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSC 218
C +PGIP+ R+ G + + +V++ C G L + C++ WS P+C
Sbjct: 1010 CLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTC 1063
Score = 40.4 bits (93), Expect = 0.006
Identities = 18/59 (30%), Positives = 30/59 (50%), Gaps = 4/59 (6%)
Query: 165 CSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQE----GGSWSGTEPSCQ 219
C +PG P +++GS + L +V + C L+G++ TCQ +WS P C+
Sbjct: 486 CPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCK 544
Score = 40.4 bits (93), Expect = 0.006
Identities = 17/54 (31%), Positives = 24/54 (44%)
Query: 165 CSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSC 218
C +PG P+ + G + D + + C G L G + CQE WS P C
Sbjct: 664 CGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPIC 717
Score = 40.0 bits (92), Expect = 0.008
Identities = 32/125 (25%), Positives = 49/125 (39%), Gaps = 16/125 (12%)
Query: 109 FENGEYWPRSPYYNVSDEIS--FHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGY-- 164
F W +Y+ D + Y G T+ N T N + Q+ I + AG+
Sbjct: 1984 FATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSN-NLYLNFQSDISVSAAGFHL 2042
Query: 165 ---------CSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEG--GSWSG 213
C P P K+G +Y + D V++ C +G +L+G TC G W+
Sbjct: 2043 EYTAIGLDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNY 2102
Query: 214 TEPSC 218
P C
Sbjct: 2103 PIPIC 2107
Score = 38.5 bits (88), Expect = 0.024
Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 16/81 (19%)
Query: 103 CPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTC--QVNGRWSGQTAICD- 159
CP P F NG + V ISF C+ GYTL G++ TC V+ W+ C+
Sbjct: 2224 CPDPRPFRNGFVIGND--FTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEA 2281
Query: 160 ---------NGAGYCSNPGIP 171
NG Y +PG P
Sbjct: 2282 LCGGNITAMNGTIY--SPGYP 2300
Score = 37.0 bits (84), Expect = 0.069
Identities = 17/57 (29%), Positives = 27/57 (47%), Gaps = 3/57 (5%)
Query: 165 CSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTC---QEGGSWSGTEPSC 218
C +PG+P+ + G D+V + C G L+G +R TC + W + P C
Sbjct: 1528 CRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVC 1584
Score = 35.8 bits (81), Expect = 0.15
Identities = 18/59 (30%), Positives = 26/59 (44%), Gaps = 4/59 (6%)
Query: 165 CSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTC----QEGGSWSGTEPSCQ 219
C NPG+P G+++ + D + Y C G L G + TC SW P C+
Sbjct: 178 CGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICR 236
Score = 34.3 bits (77), Expect = 0.45
Identities = 18/60 (30%), Positives = 29/60 (48%), Gaps = 6/60 (10%)
Query: 103 CPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQ----VNGRWSGQTAIC 158
CP P + ENG+ +++ + F C + Y L+G+ + TCQ V WS +C
Sbjct: 486 CPDPGEPENGKRIGSD--FSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVC 543
Score = 34.3 bits (77), Expect = 0.45
Identities = 21/81 (25%), Positives = 31/81 (38%), Gaps = 12/81 (14%)
Query: 103 CPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGR--WSGQTAICD- 159
C P N E + + D I + C G+TL G+A TC++ R G +C
Sbjct: 2395 CQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQV 2454
Query: 160 ---------NGAGYCSNPGIP 171
+ G +PG P
Sbjct: 2455 LCPANELRLDSTGVILSPGYP 2475
Score = 33.5 bits (75), Expect = 0.76
Identities = 16/51 (31%), Positives = 22/51 (43%), Gaps = 8/51 (15%)
Query: 116 PRSPYYNVS--------DEISFHCYDGYTLRGSANRTCQVNGRWSGQTAIC 158
P +P Y + D + F C G+ L G + CQ N +WS IC
Sbjct: 667 PGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPIC 717
Score = 33.5 bits (75), Expect = 0.76
Identities = 18/54 (33%), Positives = 26/54 (48%), Gaps = 4/54 (7%)
Query: 121 YNVSDEISFHCYDGYTLRGSANRTCQVNGR--WSGQTAIC--DNGAGYCSNPGI 170
+ + D ++F C GY L G++ C GR WS C + GA +N GI
Sbjct: 1198 FGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAECGASATNNEGI 1251
Score = 32.0 bits (71), Expect = 2.2
Identities = 16/58 (27%), Positives = 29/58 (50%), Gaps = 4/58 (6%)
Query: 165 CSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQ----EGGSWSGTEPSC 218
CS+ P R++G+++ + SV + C+ G L GS C+ W+ + P+C
Sbjct: 1878 CSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTC 1935
Score = 30.8 bits (68), Expect = 4.9
Identities = 13/45 (28%), Positives = 24/45 (53%), Gaps = 2/45 (4%)
Query: 177 VGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGS--WSGTEPSCQ 219
+G+ + + ++++ C G TL G+ TC G S W+ P C+
Sbjct: 2236 IGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCE 2280
Score = 30.0 bits (66), Expect = 8.4
Identities = 16/59 (27%), Positives = 23/59 (38%), Gaps = 8/59 (13%)
Query: 121 YNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICD--------NGAGYCSNPGIP 171
+++ +SF C GY L C+ N WS CD +G +PG P
Sbjct: 1026 FSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYP 1084
>gi|148886654 polydom [Homo sapiens]
Length = 3571
Score = 91.3 bits (225), Expect = 3e-18
Identities = 53/181 (29%), Positives = 77/181 (42%), Gaps = 26/181 (14%)
Query: 43 EIKGGSFRLLQEGQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIH 102
+++G + +E +EY C GF ++R C + GSWS +C +
Sbjct: 2843 QVRGDEYTFQKE---IEYTCNEGFLLEGARSRVCLANGSWSGATP---------DCVPVR 2890
Query: 103 CPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGA 162
C P NG Y E++FHC++GY L G+ TCQ +G W + +C
Sbjct: 2891 CATPPQLANGV--TEGLDYGFMKEVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCK--P 2946
Query: 163 GYCSNP-----GIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPS 217
C P G P G + + + Y C G L G+ R C GSWSG+ PS
Sbjct: 2947 VNCGPPEDLAHGFPNGFSFIHGGH-----IQYQCFPGYKLHGNSSRRCLSNGSWSGSSPS 3001
Query: 218 C 218
C
Sbjct: 3002 C 3002
Score = 88.2 bits (217), Expect = 3e-17
Identities = 48/164 (29%), Positives = 67/164 (40%), Gaps = 13/164 (7%)
Query: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEY 114
G A++Y C G R C WS + C AI C +P+ NG
Sbjct: 2736 GSAVQYSCKPGHILAGSDLRLCLENRKWSGASPR---------CEAISCKKPNPVMNGSI 2786
Query: 115 WPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGT 174
+ Y + + C GY L G+ RTCQ + W IC CS+P +
Sbjct: 2787 --KGSNYTYLSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVD--CSSPPVSANG 2842
Query: 175 RKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSC 218
+ G +Y + + Y C+ G L G++ R C GSWSG P C
Sbjct: 2843 QVRGDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDC 2886
Score = 87.4 bits (215), Expect = 4e-17
Identities = 56/191 (29%), Positives = 80/191 (41%), Gaps = 17/191 (8%)
Query: 44 IKGGSFRLLQEGQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHC 103
IKG ++ L L Y C G+ + RTC+ +W +D+ C + C
Sbjct: 2786 IKGSNYTYLS---TLYYECDPGYVLNGTERRTCQDDKNWD----EDEPI-----CIPVDC 2833
Query: 104 PRPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAG 163
P NG+ R Y EI + C +G+ L G+ +R C NG WSG T C
Sbjct: 2834 SSPPVSANGQV--RGDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDCVPVR- 2890
Query: 164 YCSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDSFM 223
C+ P G Y VT+HC G L G+ + TCQ G+W P C+
Sbjct: 2891 -CATPPQLANGVTEGLDYGFMKEVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCK-PVN 2948
Query: 224 YDTPQEVAEAF 234
P+++A F
Sbjct: 2949 CGPPEDLAHGF 2959
Score = 82.0 bits (201), Expect = 2e-15
Identities = 56/199 (28%), Positives = 79/199 (39%), Gaps = 21/199 (10%)
Query: 52 LQEGQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFEN 111
L G ++Y C GF+ T C+ G+WS+ EC + CP+P + N
Sbjct: 2398 LHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSS---------PLPECVPVECPQPEEIPN 2448
Query: 112 GEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIP 171
G + Y + C G+ L G+ C NG W G C A C P
Sbjct: 2449 GIIDVQGLAY--LSTALYTCKPGFELVGNTTTLCGENGHWLGGKPTCK--AIECLKPKEI 2504
Query: 172 IGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDSFMYDTPQEVA 231
+ + + +VTY C+RG L G TC E G W PSC ++ D+PQ +
Sbjct: 2505 LNGKFSYTDLHYGQTVTYSCNRGFRLEGPSALTCLETGDWDVDAPSC-NAIHCDSPQPIE 2563
Query: 232 EAFLSSLTETIEGVDAEDG 250
F +EG D G
Sbjct: 2564 NGF-------VEGADYSYG 2575
Score = 77.8 bits (190), Expect = 4e-14
Identities = 47/164 (28%), Positives = 69/164 (42%), Gaps = 13/164 (7%)
Query: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEY 114
G + Y C G+ C+ G+W+ C +I C P ENG
Sbjct: 2678 GTMVSYTCNPGYELLGNPVLICQEDGTWNG---------SAPSCISIECDLPTAPENG-- 2726
Query: 115 WPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGT 174
+ R ++ + + C G+ L GS R C N +WSG + C+ A C P +
Sbjct: 2727 FLRFTETSMGSAVQYSCKPGHILAGSDLRLCLENRKWSGASPRCE--AISCKKPNPVMNG 2784
Query: 175 RKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSC 218
GS Y ++ Y C G L G++RRTCQ+ +W EP C
Sbjct: 2785 SIKGSNYTYLSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPIC 2828
Score = 74.3 bits (181), Expect = 4e-13
Identities = 44/157 (28%), Positives = 66/157 (42%), Gaps = 12/157 (7%)
Query: 73 TRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEYWPRSPYYNVSDEISFHCY 132
T TC+ G W + C CP P + + ++V+ ++S C
Sbjct: 3160 TFTCQKDGRWFP---------ERISCSPKKCPLPENITH--ILVHGDDFSVNRQVSVSCA 3208
Query: 133 DGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGTRKVGSQYRLEDSVTYHCS 192
+GYT G CQ++G W + C P P VGS+Y E ++ Y C
Sbjct: 3209 EGYTFEGVNISVCQLDGTWEPPFSDESCSPVSCGKPESPEHGFVVGSKYTFESTIIYQCE 3268
Query: 193 RGLTLRGSQRRTCQEGGSWSGTEPSCQDSFMYDTPQE 229
G L G++ R CQE WSG C+++ +TP E
Sbjct: 3269 PGYELEGNRERVCQENRQWSGGVAICKET-RCETPLE 3304
Score = 73.6 bits (179), Expect = 7e-13
Identities = 44/158 (27%), Positives = 63/158 (39%), Gaps = 11/158 (6%)
Query: 62 CPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEYWPRSPYY 121
C G+ V C+ G+W + + C + C +P E+G + Y
Sbjct: 3207 CAEGYTFEGVNISVCQLDGTWEPPFSDES-------CSPVSCGKPESPEHG--FVVGSKY 3257
Query: 122 NVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGTRKVGSQY 181
I + C GY L G+ R CQ N +WSG AIC C P + +
Sbjct: 3258 TFESTIIYQCEPGYELEGNRERVCQENRQWSGGVAICKETR--CETPLEFLNGKADIENR 3315
Query: 182 RLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
+V Y C+RG +L G C E G+WS P C+
Sbjct: 3316 TTGPNVVYSCNRGYSLEGPSEAHCTENGTWSHPVPLCK 3353
Score = 73.2 bits (178), Expect = 9e-13
Identities = 52/197 (26%), Positives = 71/197 (36%), Gaps = 36/197 (18%)
Query: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQ----DQKTV-----RKAEC------- 98
G + Y C +G+Y C GSW+ + D+ V A C
Sbjct: 1709 GSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLDVDECAVGSDCSEHASCLNVDGSY 1768
Query: 99 ----------------RAIHCPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSAN 142
I C P + ENG Y V E++F C +GY L G
Sbjct: 1769 ICSCVPPYTGDGKNCAEPIKCKAPGNPENGH--SSGEIYTVGAEVTFSCQEGYQLMGVTK 1826
Query: 143 RTCQVNGRWSGQTAICDNGAGYCSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQR 202
TC +G W+ C A C P IP + VTY C++G TL G +
Sbjct: 1827 ITCLESGEWNHLIPYCK--AVSCGKPAIPENGCIEELAFTFGSKVTYRCNKGYTLAGDKE 1884
Query: 203 RTCQEGGSWSGTEPSCQ 219
+C SWS + P C+
Sbjct: 1885 SSCLANSSWSHSPPVCE 1901
Score = 72.8 bits (177), Expect = 1e-12
Identities = 52/200 (26%), Positives = 77/200 (38%), Gaps = 14/200 (7%)
Query: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEY 114
G + Y C GFY + TC +TG WS+ C + C P ENG +
Sbjct: 2165 GAMVAYSCNKGFYIKGEKKSTCEATGQWSS---------PIPTCHPVSCGEPPKVENG-F 2214
Query: 115 WPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGT 174
+ E+ + C GY GS CQ N W ++ + P I G
Sbjct: 2215 LEHTTGRIFESEVRYQCNPGYKSVGSPVFVCQANRHWHSESPLMCVPLDCGKPPPIQNGF 2274
Query: 175 RKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWS-GTEPSCQDSFMYDTPQEVAEA 233
K G + + V + C+ G L G TCQ+ G W+ + P C + + P +
Sbjct: 2275 MK-GENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKCMPAKCPEPPLLENQL 2333
Query: 234 FLSSLTETIEGV--DAEDGH 251
L LT + V ++GH
Sbjct: 2334 VLKELTTEVGVVTFSCKEGH 2353
Score = 72.8 bits (177), Expect = 1e-12
Identities = 72/262 (27%), Positives = 94/262 (35%), Gaps = 60/262 (22%)
Query: 39 LEGVEIKGGSFRL--LQEGQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKA 96
L+ EI G F L GQ + Y C GF TC TG W V
Sbjct: 2499 LKPKEILNGKFSYTDLHYGQTVTYSCNRGFRLEGPSALTCLETGDWD---------VDAP 2549
Query: 97 ECRAIHCPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTA 156
C AIHC P ENG + Y+ I + C+ G+ + G A +TC+ +G WS
Sbjct: 2550 SCNAIHCDSPQPIENG--FVEGADYSYGAIIIYSCFPGFQVAGHAMQTCEESG-WSSSIP 2606
Query: 157 IC---DNGA------GYCS-----------------------NPGIPIGT---------- 174
C D G G C+ +P +G
Sbjct: 2607 TCMPIDCGLPPHIDFGDCTKLKDDQGYFEQEDDMMEVPYVTPHPPYHLGAVAKTWENTKE 2666
Query: 175 --RKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDSFMYDTPQEVAE 232
S + V+Y C+ G L G+ CQE G+W+G+ PSC S D P
Sbjct: 2667 SPATHSSNFLYGTMVSYTCNPGYELLGNPVLICQEDGTWNGSAPSC-ISIECDLPTAPEN 2725
Query: 233 AFLSSLTETIEGVDAEDGHGPG 254
FL TET G + PG
Sbjct: 2726 GFL-RFTETSMGSAVQYSCKPG 2746
Score = 69.3 bits (168), Expect = 1e-11
Identities = 43/173 (24%), Positives = 69/173 (39%), Gaps = 13/173 (7%)
Query: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEY 114
G + + C G+ V TC +G W+ L C+A+ C +P ENG
Sbjct: 1808 GAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPY---------CKAVSCGKPAIPENGCI 1858
Query: 115 WPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGT 174
+ + ++++ C GYTL G +C N WS +C+ CS+P
Sbjct: 1859 EELA--FTFGSKVTYRCNKGYTLAGDKESSCLANSSWSHSPPVCEPVK--CSSPENINNG 1914
Query: 175 RKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDSFMYDTP 227
+ + S + +Y C G +L+G C G W P+C F + P
Sbjct: 1915 KYILSGLTYLSTASYSCDTGYSLQGPSIIECTASGIWDRAPPACHLVFCGEPP 1967
Score = 68.2 bits (165), Expect = 3e-11
Identities = 46/160 (28%), Positives = 68/160 (42%), Gaps = 16/160 (10%)
Query: 60 YVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEYWPRSP 119
Y C GF T C G W K C+AI C +P + NG++
Sbjct: 2464 YTCKPGFELVGNTTTLCGENGHWLG---------GKPTCKAIECLKPKEILNGKFSYTDL 2514
Query: 120 YYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGTRKV-G 178
+Y + +++ C G+ L G + TC G W C+ A +C +P PI V G
Sbjct: 2515 HYGQT--VTYSCNRGFRLEGPSALTCLETGDWDVDAPSCN--AIHCDSPQ-PIENGFVEG 2569
Query: 179 SQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSC 218
+ Y + Y C G + G +TC+E G WS + P+C
Sbjct: 2570 ADYSYGAIIIYSCFPGFQVAGHAMQTCEESG-WSSSIPTC 2608
Score = 67.4 bits (163), Expect = 5e-11
Identities = 47/189 (24%), Positives = 67/189 (35%), Gaps = 7/189 (3%)
Query: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEY 114
G Y C G+ C + G W + QD C A C +P
Sbjct: 2040 GDIAFYYCSDGYSLADNSQLLCNAQGKWVPPEGQDMP-----RCIAHFCEKPPSVSYSIL 2094
Query: 115 WPRSPY-YNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIG 173
S + +SF C +G+ L SA C G+W+ C P +
Sbjct: 2095 ESVSKAKFAAGSVVSFKCMEGFVLNTSAKIECMRGGQWNPSPMSIQCIPVRCGEPPSIMN 2154
Query: 174 TRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDSFMYDTPQEVAEA 233
GS Y V Y C++G ++G ++ TC+ G WS P+C P +V
Sbjct: 2155 GYASGSNYSFGAMVAYSCNKGFYIKGEKKSTCEATGQWSSPIPTCH-PVSCGEPPKVENG 2213
Query: 234 FLSSLTETI 242
FL T I
Sbjct: 2214 FLEHTTGRI 2222
Score = 66.6 bits (161), Expect = 8e-11
Identities = 51/190 (26%), Positives = 77/190 (40%), Gaps = 17/190 (8%)
Query: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEY 114
G ++Y C G+ + +R C S GSWS C C P E G
Sbjct: 2968 GGHIQYQCFPGYKLHGNSSRRCLSNGSWSG---------SSPSCLPCRCSTPV-IEYGTV 3017
Query: 115 WPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSN-PGIPIG 173
++ C+ G+ L G + TC+ +G+WS C++ + C + P IP
Sbjct: 3018 --NGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTS--CGSLPMIPNA 3073
Query: 174 TRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDSFMYDTPQEVAEA 233
S ++ E+ +TY C G ++GS C E G WS P C + +P VA A
Sbjct: 3074 FISETSSWK-ENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVC-EPLSCGSPPSVANA 3131
Query: 234 FLSSLTETIE 243
+ T E
Sbjct: 3132 VATGEAHTYE 3141
Score = 65.1 bits (157), Expect = 2e-10
Identities = 41/164 (25%), Positives = 61/164 (37%), Gaps = 13/164 (7%)
Query: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEY 114
G + Y C G+ + +C + SWS C + C P + NG+Y
Sbjct: 1866 GSKVTYRCNKGYTLAGDKESSCLANSSWSH---------SPPVCEPVKCSSPENINNGKY 1916
Query: 115 WPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGT 174
Y S+ C GY+L+G + C +G W C +C P
Sbjct: 1917 ILSGLTY--LSTASYSCDTGYSLQGPSIIECTASGIWDRAPPACH--LVFCGEPPAIKDA 1972
Query: 175 RKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSC 218
G+ + ++VTY C G TL G C G WS ++ C
Sbjct: 1973 VITGNNFTFRNTVTYTCKEGYTLAGLDTIECLADGKWSRSDQQC 2016
Score = 62.8 bits (151), Expect = 1e-09
Identities = 46/179 (25%), Positives = 75/179 (41%), Gaps = 22/179 (12%)
Query: 44 IKGGSFRLLQEGQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHC 103
+KG +F + G +++ C G+ + TC+ +G W+ K + K C C
Sbjct: 2275 MKGENFEV---GSKVQFFCNEGYELVGDSSWTCQKSGKWN--KKSNPK------CMPAKC 2323
Query: 104 PRPHDFENGEYWPRSPYYNVSDEI---SFHCYDGYTLRGSANRTCQVNGRWSGQTAICDN 160
P P EN + ++ E+ +F C +G+ L+G + C + +W+ +C
Sbjct: 2324 PEPPLLEN-----QLVLKELTTEVGVVTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCK- 2377
Query: 161 GAGYCSNPG-IPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSC 218
C+ P I G S +V Y C G LRG+ CQ G+WS P C
Sbjct: 2378 -IVLCTPPPLISFGVPIPSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPEC 2435
Score = 62.0 bits (149), Expect = 2e-09
Identities = 50/207 (24%), Positives = 68/207 (32%), Gaps = 50/207 (24%)
Query: 52 LQEGQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFEN 111
L+ G + C GF + C + G W T C I C P EN
Sbjct: 1648 LKPGSKVNLFCDPGFQLVGNPVQYCLNQGQW---------TQPLPHCERISCGVPPPLEN 1698
Query: 112 GEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSG------------------ 153
G + +Y +++ C +GY L G + C NG W+G
Sbjct: 1699 G-FHSADDFY-AGSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLDVDECAVGSDCS 1756
Query: 154 QTAICDNGAGY---------------------CSNPGIPIGTRKVGSQYRLEDSVTYHCS 192
+ A C N G C PG P G Y + VT+ C
Sbjct: 1757 EHASCLNVDGSYICSCVPPYTGDGKNCAEPIKCKAPGNPENGHSSGEIYTVGAEVTFSCQ 1816
Query: 193 RGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
G L G + TC E G W+ P C+
Sbjct: 1817 EGYQLMGVTKITCLESGEWNHLIPYCK 1843
Score = 61.2 bits (147), Expect = 3e-09
Identities = 42/165 (25%), Positives = 62/165 (37%), Gaps = 13/165 (7%)
Query: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEY 114
G + Y C G+ C G+WS C+ CP P
Sbjct: 3318 GPNVVYSCNRGYSLEGPSEAHCTENGTWSHPVPL---------CKPNPCPVPFVIPENAL 3368
Query: 115 WPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGT 174
+Y V +S C +G+ L+G TC + W+ +A C+ + C P
Sbjct: 3369 LSEKEFY-VDQNVSIKCREGFLLQGHGIITCNPDETWTQTSAKCEKIS--CGPPAHVENA 3425
Query: 175 RKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
G Y+ D +TY C G L G R C E G+W+ + P C+
Sbjct: 3426 IARGVHYQYGDMITYSCYSGYMLEGFLRSVCLENGTWT-SPPICR 3469
Score = 60.8 bits (146), Expect = 4e-09
Identities = 51/186 (27%), Positives = 72/186 (38%), Gaps = 27/186 (14%)
Query: 55 GQALEY---VCPSGFY-------------PYPVQTRTCRSTGSWSTLKTQDQKTVRKA-- 96
G+ L+Y CPSG Y P P + T GS S ++ R +
Sbjct: 313 GKGLQYECTACPSGTYKPEGSPGGISSCIPCPDENHTS-PPGSTSPEDCVCREGYRASGQ 371
Query: 97 ECRAIHCPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTA 156
C +HCP ENG + + + + C+ G+ L GS+ C NG WSG +
Sbjct: 372 TCELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGSSIILCLPNGLWSGSES 431
Query: 157 ICD-NGAGYCSNP---GIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWS 212
C + P I TR++ + + C G L GS + TCQ W
Sbjct: 432 YCRVRTCPHLRQPKHGHISCSTREM----LYKTTCLVACDEGYRLEGSDKLTCQGNSQWD 487
Query: 213 GTEPSC 218
G EP C
Sbjct: 488 GPEPRC 493
Score = 55.8 bits (133), Expect = 1e-07
Identities = 30/93 (32%), Positives = 41/93 (44%), Gaps = 2/93 (2%)
Query: 127 ISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGTRKVGSQYRLEDS 186
+S+ C GY L G+ CQ +G W+G C + C P P ++ + +
Sbjct: 2681 VSYTCNPGYELLGNPVLICQEDGTWNGSAPSCISIE--CDLPTAPENGFLRFTETSMGSA 2738
Query: 187 VTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
V Y C G L GS R C E WSG P C+
Sbjct: 2739 VQYSCKPGHILAGSDLRLCLENRKWSGASPRCE 2771
Score = 55.5 bits (132), Expect = 2e-07
Identities = 41/166 (24%), Positives = 66/166 (39%), Gaps = 18/166 (10%)
Query: 60 YVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEYWPRSP 119
Y C G+ + T C + G WS DQ +C A+ C P ++ P +
Sbjct: 1987 YTCKEGYTLAGLDTIECLADGKWSR---SDQ------QCLAVSCDEPPIVDHAS--PETA 2035
Query: 120 YYNVSDEISFHCYDGYTLRGSANRTCQVNGRW---SGQTAICDNGAGYCSNP---GIPIG 173
+ D ++C DGY+L ++ C G+W GQ + A +C P I
Sbjct: 2036 HRLFGDIAFYYCSDGYSLADNSQLLCNAQGKWVPPEGQD-MPRCIAHFCEKPPSVSYSIL 2094
Query: 174 TRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
+++ V++ C G L S + C GG W+ + S Q
Sbjct: 2095 ESVSKAKFAAGSVVSFKCMEGFVLNTSAKIECMRGGQWNPSPMSIQ 2140
Score = 52.4 bits (124), Expect = 2e-06
Identities = 27/95 (28%), Positives = 42/95 (44%), Gaps = 2/95 (2%)
Query: 126 EISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGTRKVGSQYRLED 185
+++ C G+ L G+ + C G+W+ C+ + C P +
Sbjct: 1653 KVNLFCDPGFQLVGNPVQYCLNQGQWTQPLPHCERIS--CGVPPPLENGFHSADDFYAGS 1710
Query: 186 SVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQD 220
+VTY C+ G L G R C + GSW+G PSC D
Sbjct: 1711 TVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLD 1745
Score = 51.6 bits (122), Expect = 3e-06
Identities = 37/163 (22%), Positives = 67/163 (41%), Gaps = 13/163 (7%)
Query: 58 LEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEYWPR 117
+ Y C G+ C++ W + C + C +P +NG + +
Sbjct: 2227 VRYQCNPGYKSVGSPVFVCQANRHWHSESP--------LMCVPLDCGKPPPIQNG--FMK 2276
Query: 118 SPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGTRKV 177
+ V ++ F C +GY L G ++ TCQ +G+W+ ++ A C P + + + V
Sbjct: 2277 GENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKCMPAK-CPEPPL-LENQLV 2334
Query: 178 GSQYRLEDSV-TYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
+ E V T+ C G L+G C W+ + P C+
Sbjct: 2335 LKELTTEVGVVTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCK 2377
Score = 50.1 bits (118), Expect = 8e-06
Identities = 35/120 (29%), Positives = 42/120 (35%), Gaps = 19/120 (15%)
Query: 56 QALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEYW 115
Q + C GF TC +W T A+C I C P EN
Sbjct: 3378 QNVSIKCREGFLLQGHGIITCNPDETW---------TQTSAKCEKISCGPPAHVENAI-- 3426
Query: 116 PRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAI-------CDNGAGYCSNP 168
R +Y D I++ CY GY L G C NG W+ C NG G C P
Sbjct: 3427 ARGVHYQYGDMITYSCYSGYMLEGFLRSVCLENGTWTSPPICRAVCRFPCQNG-GICQRP 3485
Score = 42.4 bits (98), Expect = 0.002
Identities = 47/225 (20%), Positives = 95/225 (42%), Gaps = 32/225 (14%)
Query: 252 GPGEQQKRKIVLDPSGSMNIYLVLDGSDSIGASNFTGAKKCLVNLIEKVASYGVKPRYGL 311
G +++ +++ + S + + ++D S S+G NF + L+ R +
Sbjct: 65 GQAFRRRVRLLRELSERLELVFLVDDSSSVGEVNFRSELMFVRKLLSDFPVVPTATRVAI 124
Query: 312 VTYAT----YPKI-WVKVSEADSSNADWVTKQLNEINYEDHKLKSGTNTKKALQAVYSMM 366
VT+++ P++ ++ A + +++ I+Y GT TK A Q ++
Sbjct: 125 VTFSSKNYVVPRVDYISTRRARQHKCALLLQEIPAISYRG----GGTYTKGAFQQAAQIL 180
Query: 367 SWPDDVPPEGWNRTRHVIILMTDGLHNMGGDPITVIDEIRDLLYIGKDRKNPREDYLDVY 426
+ N T+ V+ L+TDG N GGDP + +RD ++++
Sbjct: 181 LHARE------NSTK-VVFLITDGYSN-GGDPRPIAASLRD-------------SGVEIF 219
Query: 427 VFGVGPLVNQVNINALASKKDNEQHVFKVKDMENLEDVFYQMIDE 471
FG+ N +N +AS E+H + + E E + + + E
Sbjct: 220 TFGIWQ-GNIRELNDMAS-TPKEEHCYLLHSFEEFEALARRALHE 262
>gi|62912468 complement component 4 binding protein, beta chain
isoform 1 precursor [Homo sapiens]
Length = 252
Score = 88.2 bits (217), Expect = 3e-17
Identities = 60/189 (31%), Positives = 87/189 (46%), Gaps = 17/189 (8%)
Query: 54 EGQAL-EYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENG 112
EGQ L YVC G++ +T C ++ W T ECR HCP P NG
Sbjct: 40 EGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTT---------ECRLGHCPDPV-LVNG 89
Query: 113 EYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPI 172
E+ P NVSD+I+F C D Y L+GS C + W+ IC + C PG P+
Sbjct: 90 EFSSSGPV-NVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRD--CDPPGNPV 146
Query: 173 GTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDSFMYDTPQEVAE 232
G+ + L +++Y+C L G Q + C + G WS P C+ + + P+ E
Sbjct: 147 HGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVD-GEWSSALPVCK--LIQEAPKPECE 203
Query: 233 AFLSSLTET 241
L + E+
Sbjct: 204 KALLAFQES 212
Score = 52.8 bits (125), Expect = 1e-06
Identities = 32/122 (26%), Positives = 50/122 (40%), Gaps = 8/122 (6%)
Query: 100 AIHCPRPHDFENGEYWPRSPYYNVSDEI--SFHCYDGYTLRGSANRTCQVNGRWSGQTAI 157
A HCP +N + + V +I ++ C GY L G C + W T
Sbjct: 20 AEHCPELPPVDNSIFVAKE----VEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTE 75
Query: 158 CDNGAGYCSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPS 217
C G+C +P + G + D +T+ C+ L+GS R C E +W+ P
Sbjct: 76 CR--LGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPI 133
Query: 218 CQ 219
C+
Sbjct: 134 CK 135
>gi|62912466 complement component 4 binding protein, beta chain
isoform 2 precursor [Homo sapiens]
Length = 251
Score = 88.2 bits (217), Expect = 3e-17
Identities = 60/189 (31%), Positives = 87/189 (46%), Gaps = 17/189 (8%)
Query: 54 EGQAL-EYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENG 112
EGQ L YVC G++ +T C ++ W T ECR HCP P NG
Sbjct: 39 EGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTT---------ECRLGHCPDPV-LVNG 88
Query: 113 EYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPI 172
E+ P NVSD+I+F C D Y L+GS C + W+ IC + C PG P+
Sbjct: 89 EFSSSGPV-NVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRD--CDPPGNPV 145
Query: 173 GTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDSFMYDTPQEVAE 232
G+ + L +++Y+C L G Q + C + G WS P C+ + + P+ E
Sbjct: 146 HGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVD-GEWSSALPVCK--LIQEAPKPECE 202
Query: 233 AFLSSLTET 241
L + E+
Sbjct: 203 KALLAFQES 211
Score = 52.4 bits (124), Expect = 2e-06
Identities = 31/120 (25%), Positives = 49/120 (40%), Gaps = 8/120 (6%)
Query: 102 HCPRPHDFENGEYWPRSPYYNVSDEI--SFHCYDGYTLRGSANRTCQVNGRWSGQTAICD 159
HCP +N + + V +I ++ C GY L G C + W T C
Sbjct: 21 HCPELPPVDNSIFVAKE----VEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTECR 76
Query: 160 NGAGYCSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
G+C +P + G + D +T+ C+ L+GS R C E +W+ P C+
Sbjct: 77 --LGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICK 134
>gi|62912464 complement component 4 binding protein, beta chain
isoform 1 precursor [Homo sapiens]
Length = 252
Score = 88.2 bits (217), Expect = 3e-17
Identities = 60/189 (31%), Positives = 87/189 (46%), Gaps = 17/189 (8%)
Query: 54 EGQAL-EYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENG 112
EGQ L YVC G++ +T C ++ W T ECR HCP P NG
Sbjct: 40 EGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTT---------ECRLGHCPDPV-LVNG 89
Query: 113 EYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPI 172
E+ P NVSD+I+F C D Y L+GS C + W+ IC + C PG P+
Sbjct: 90 EFSSSGPV-NVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRD--CDPPGNPV 146
Query: 173 GTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDSFMYDTPQEVAE 232
G+ + L +++Y+C L G Q + C + G WS P C+ + + P+ E
Sbjct: 147 HGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVD-GEWSSALPVCK--LIQEAPKPECE 203
Query: 233 AFLSSLTET 241
L + E+
Sbjct: 204 KALLAFQES 212
Score = 52.8 bits (125), Expect = 1e-06
Identities = 32/122 (26%), Positives = 50/122 (40%), Gaps = 8/122 (6%)
Query: 100 AIHCPRPHDFENGEYWPRSPYYNVSDEI--SFHCYDGYTLRGSANRTCQVNGRWSGQTAI 157
A HCP +N + + V +I ++ C GY L G C + W T
Sbjct: 20 AEHCPELPPVDNSIFVAKE----VEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTE 75
Query: 158 CDNGAGYCSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPS 217
C G+C +P + G + D +T+ C+ L+GS R C E +W+ P
Sbjct: 76 CR--LGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPI 133
Query: 218 CQ 219
C+
Sbjct: 134 CK 135
>gi|62912462 complement component 4 binding protein, beta chain
isoform 2 precursor [Homo sapiens]
Length = 251
Score = 88.2 bits (217), Expect = 3e-17
Identities = 60/189 (31%), Positives = 87/189 (46%), Gaps = 17/189 (8%)
Query: 54 EGQAL-EYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENG 112
EGQ L YVC G++ +T C ++ W T ECR HCP P NG
Sbjct: 39 EGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTT---------ECRLGHCPDPV-LVNG 88
Query: 113 EYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPI 172
E+ P NVSD+I+F C D Y L+GS C + W+ IC + C PG P+
Sbjct: 89 EFSSSGPV-NVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRD--CDPPGNPV 145
Query: 173 GTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDSFMYDTPQEVAE 232
G+ + L +++Y+C L G Q + C + G WS P C+ + + P+ E
Sbjct: 146 HGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVD-GEWSSALPVCK--LIQEAPKPECE 202
Query: 233 AFLSSLTET 241
L + E+
Sbjct: 203 KALLAFQES 211
Score = 52.4 bits (124), Expect = 2e-06
Identities = 31/120 (25%), Positives = 49/120 (40%), Gaps = 8/120 (6%)
Query: 102 HCPRPHDFENGEYWPRSPYYNVSDEI--SFHCYDGYTLRGSANRTCQVNGRWSGQTAICD 159
HCP +N + + V +I ++ C GY L G C + W T C
Sbjct: 21 HCPELPPVDNSIFVAKE----VEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTECR 76
Query: 160 NGAGYCSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
G+C +P + G + D +T+ C+ L+GS R C E +W+ P C+
Sbjct: 77 --LGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICK 134
>gi|4502505 complement component 4 binding protein, beta chain
isoform 1 precursor [Homo sapiens]
Length = 252
Score = 88.2 bits (217), Expect = 3e-17
Identities = 60/189 (31%), Positives = 87/189 (46%), Gaps = 17/189 (8%)
Query: 54 EGQAL-EYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENG 112
EGQ L YVC G++ +T C ++ W T ECR HCP P NG
Sbjct: 40 EGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTT---------ECRLGHCPDPV-LVNG 89
Query: 113 EYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPI 172
E+ P NVSD+I+F C D Y L+GS C + W+ IC + C PG P+
Sbjct: 90 EFSSSGPV-NVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRD--CDPPGNPV 146
Query: 173 GTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDSFMYDTPQEVAE 232
G+ + L +++Y+C L G Q + C + G WS P C+ + + P+ E
Sbjct: 147 HGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVD-GEWSSALPVCK--LIQEAPKPECE 203
Query: 233 AFLSSLTET 241
L + E+
Sbjct: 204 KALLAFQES 212
Score = 52.8 bits (125), Expect = 1e-06
Identities = 32/122 (26%), Positives = 50/122 (40%), Gaps = 8/122 (6%)
Query: 100 AIHCPRPHDFENGEYWPRSPYYNVSDEI--SFHCYDGYTLRGSANRTCQVNGRWSGQTAI 157
A HCP +N + + V +I ++ C GY L G C + W T
Sbjct: 20 AEHCPELPPVDNSIFVAKE----VEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTE 75
Query: 158 CDNGAGYCSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPS 217
C G+C +P + G + D +T+ C+ L+GS R C E +W+ P
Sbjct: 76 CR--LGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPI 133
Query: 218 CQ 219
C+
Sbjct: 134 CK 135
>gi|92110053 CUB and Sushi multiple domains 2 [Homo sapiens]
Length = 3487
Score = 87.0 bits (214), Expect = 6e-17
Identities = 53/166 (31%), Positives = 72/166 (43%), Gaps = 13/166 (7%)
Query: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEY 114
G ++ Y C G+ TC GSW T +C + C P G
Sbjct: 3031 GSSVTYACLEGYQLSLPAVFTCEGNGSW---------TGELPQCFPVFCGDPGVPSRGRR 3081
Query: 115 WPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAIC-DNGAGYCSNPGIP-I 172
R Y S +SF C+ L GS R CQ +G WSG C D C++PG+P
Sbjct: 3082 EDRGFSYRSS--VSFSCHPPLVLVGSPRRFCQSDGTWSGTQPSCIDPTLTTCADPGVPQF 3139
Query: 173 GTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSC 218
G + Y++ +V + C +G L+GS RTC +WSGT P C
Sbjct: 3140 GIQNNSQGYQVGSTVLFRCQKGYLLQGSTTRTCLPNLTWSGTPPDC 3185
Score = 86.7 bits (213), Expect = 8e-17
Identities = 48/160 (30%), Positives = 70/160 (43%), Gaps = 12/160 (7%)
Query: 60 YVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEYWPRSP 119
Y C +GF + R C+ WS + C + C P + + S
Sbjct: 2740 YQCNAGFRLIGMSVRICQQDHHWSG---------KTPFCVLVSCGHPGSPPHSQMSGDS- 2789
Query: 120 YYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDN-GAGYCSNPGIPIGTRKVG 178
Y V + + C TL G++ R C ++G W+G C G C +PGIP ++G
Sbjct: 2790 -YTVGAVVRYSCIGKRTLVGNSTRMCGLDGHWTGSLPHCSGTSVGVCGDPGIPAHGIRLG 2848
Query: 179 SQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSC 218
+ + + C G LRGS RTCQ GSWSG++P C
Sbjct: 2849 DSFDPGTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPEC 2888
Score = 86.3 bits (212), Expect = 1e-16
Identities = 54/177 (30%), Positives = 81/177 (45%), Gaps = 18/177 (10%)
Query: 46 GGSFRLLQEGQALEYVCPSGFY--PYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHC 103
G FR + + Y C G+ + V +C +W+ K C+A+ C
Sbjct: 2965 GNDFRY---NKTVTYQCVPGYMMESHRVSVLSCTKDRTWNGTKPV---------CKALMC 3012
Query: 104 PRPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAG 163
P NG+ + S +++ C +GY L A TC+ NG W+G+ C
Sbjct: 3013 KPPPLIPNGKVVGSDFMWGSS--VTYACLEGYQLSLPAVFTCEGNGSWTGELPQCF--PV 3068
Query: 164 YCSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQD 220
+C +PG+P R+ + SV++ C L L GS RR CQ G+WSGT+PSC D
Sbjct: 3069 FCGDPGVPSRGRREDRGFSYRSSVSFSCHPPLVLVGSPRRFCQSDGTWSGTQPSCID 3125
Score = 85.1 bits (209), Expect = 2e-16
Identities = 57/185 (30%), Positives = 74/185 (40%), Gaps = 16/185 (8%)
Query: 39 LEGVEIKGGSFRLLQEGQ-----ALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTV 93
+ + ++ G +RL+ E Q L +C G+Y + C++ G WS +
Sbjct: 2596 VSSISVEHGRWRLIFETQYQFQAQLMLICDPGYYYTGQRVIRCQANGKWSLGDSTPT--- 2652
Query: 94 RKAECRAIHCPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSG 153
CR I C NG Y + F C GYTL GS R C NG WSG
Sbjct: 2653 ----CRIISCGELPIPPNGHRIGTLSVYGAT--AIFSCNSGYTLVGSRVRECMANGLWSG 2706
Query: 154 QTAICDNGAGYCSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSG 213
C AG+C P + G Y SV Y C+ G L G R CQ+ WSG
Sbjct: 2707 SEVRCL--AGHCGTPEPIVNGHINGENYSYRGSVVYQCNAGFRLIGMSVRICQQDHHWSG 2764
Query: 214 TEPSC 218
P C
Sbjct: 2765 KTPFC 2769
Score = 81.6 bits (200), Expect = 2e-15
Identities = 55/190 (28%), Positives = 80/190 (42%), Gaps = 19/190 (10%)
Query: 35 GSCSLEGVEIKGGSFRL---LQEGQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQK 91
G C G+ G RL G + + C +G RTC++ GSWS
Sbjct: 2833 GVCGDPGIPAHG--IRLGDSFDPGTVMRFSCEAGHVLRGSSERTCQANGSWSG------- 2883
Query: 92 TVRKAECRAIHCPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRW 151
+ EC I C P N S S I + C +GY G +R C VNG W
Sbjct: 2884 --SQPECGVISCGNPGTPSNARV-VFSDGLVFSSSIVYECREGYYATGLLSRHCSVNGTW 2940
Query: 152 SGQTAICDNGAGYCSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRR--TCQEGG 209
+G C C +PGIP ++G+ +R +VTY C G + + +C +
Sbjct: 2941 TGSDPEC--LVINCGDPGIPANGLRLGNDFRYNKTVTYQCVPGYMMESHRVSVLSCTKDR 2998
Query: 210 SWSGTEPSCQ 219
+W+GT+P C+
Sbjct: 2999 TWNGTKPVCK 3008
Score = 68.6 bits (166), Expect = 2e-11
Identities = 48/171 (28%), Positives = 70/171 (40%), Gaps = 15/171 (8%)
Query: 57 ALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEYWP 116
++ Y C G+Y + +R C G+W T EC I+C P NG
Sbjct: 2915 SIVYECREGYYATGLLSRHCSVNGTW---------TGSDPECLVINCGDPGIPANGLRLG 2965
Query: 117 RSPYYNVSDEISFHCYDGYTLRGS--ANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGT 174
YN + +++ C GY + + +C + W+G +C A C P +
Sbjct: 2966 NDFRYNKT--VTYQCVPGYMMESHRVSVLSCTKDRTWNGTKPVCK--ALMCKPPPLIPNG 3021
Query: 175 RKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDSFMYD 225
+ VGS + SVTY C G L TC+ GSW+G P C F D
Sbjct: 3022 KVVGSDFMWGSSVTYACLEGYQLSLPAVFTCEGNGSWTGELPQCFPVFCGD 3072
Score = 65.1 bits (157), Expect = 2e-10
Identities = 37/103 (35%), Positives = 50/103 (48%), Gaps = 10/103 (9%)
Query: 121 YNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIP----IGTRK 176
Y V + F C GY L+GS RTC N WSG C +C P P +G
Sbjct: 3148 YQVGSTVLFRCQKGYLLQGSTTRTCLPNLTWSGTPPDCV--PHHCRQPETPTHANVGALD 3205
Query: 177 VGSQYRLEDSVTYHCSRGLTLRG-SQRRTCQEGGSWSGTEPSC 218
+ S + ++ Y C G +L+G S+ RTC+ GSW+G P C
Sbjct: 3206 LPS---MGYTLIYSCQEGFSLKGGSEHRTCKADGSWTGKPPIC 3245
Score = 50.4 bits (119), Expect = 6e-06
Identities = 24/63 (38%), Positives = 36/63 (57%), Gaps = 4/63 (6%)
Query: 161 GAGYCSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQE----GGSWSGTEP 216
G C +PGIP +++GS +RL SV + C+ G L+GS+R TC + +WS P
Sbjct: 339 GHNMCPDPGIPERGKRLGSDFRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRP 398
Query: 217 SCQ 219
C+
Sbjct: 399 VCR 401
Score = 50.4 bits (119), Expect = 6e-06
Identities = 24/70 (34%), Positives = 36/70 (51%), Gaps = 2/70 (2%)
Query: 163 GYCSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDS- 221
G C +PGIP R+ GS++ D++ + C L G + TCQ+ WS +P C S
Sbjct: 519 GSCGDPGIPAYGRREGSRFHHGDTLKFECQPAFELVGQKAITCQKNNQWSAKKPGCVFSC 578
Query: 222 -FMYDTPQEV 230
F + +P V
Sbjct: 579 FFNFTSPSGV 588
Score = 45.1 bits (105), Expect = 3e-04
Identities = 18/56 (32%), Positives = 30/56 (53%)
Query: 164 YCSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
+C +PGIP+ ++ G+ + + VT+ C G TL + C+ WS PSC+
Sbjct: 866 HCLDPGIPVNGQRHGNDFYVGALVTFSCDSGYTLSDGEPLECEPNFQWSRALPSCE 921
Score = 43.9 bits (102), Expect = 6e-04
Identities = 27/107 (25%), Positives = 47/107 (43%), Gaps = 11/107 (10%)
Query: 53 QEGQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENG 112
Q G + + C G+ TRTC +WS +C HC +P +
Sbjct: 3149 QVGSTVLFRCQKGYLLQGSTTRTCLPNLTWSG---------TPPDCVPHHCRQPETPTHA 3199
Query: 113 EYWPRSPYYNVSDEISFHCYDGYTLR-GSANRTCQVNGRWSGQTAIC 158
++ + + C +G++L+ GS +RTC+ +G W+G+ IC
Sbjct: 3200 NVGALD-LPSMGYTLIYSCQEGFSLKGGSEHRTCKADGSWTGKPPIC 3245
Score = 43.5 bits (101), Expect = 7e-04
Identities = 41/188 (21%), Positives = 59/188 (31%), Gaps = 69/188 (36%)
Query: 98 CRAIHCPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRT--CQVNGRWSGQT 155
C+A+ C P +NG + + Y V + + C +GY L+ A T C G WS +
Sbjct: 2526 CQALSCGLPEAPKNGMVFGKE--YTVGTKAMYSCSEGYHLQAGAEATAECLDTGLWSNRN 2583
Query: 156 A--------------------------------------ICDNGAGY------------- 164
ICD G Y
Sbjct: 2584 VPPQCVPVTCPDVSSISVEHGRWRLIFETQYQFQAQLMLICDPGYYYTGQRVIRCQANGK 2643
Query: 165 --------------CSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGS 210
C IP ++G+ + + C+ G TL GS+ R C G
Sbjct: 2644 WSLGDSTPTCRIISCGELPIPPNGHRIGTLSVYGATAIFSCNSGYTLVGSRVRECMANGL 2703
Query: 211 WSGTEPSC 218
WSG+E C
Sbjct: 2704 WSGSEVRC 2711
Score = 42.0 bits (97), Expect = 0.002
Identities = 41/141 (29%), Positives = 51/141 (36%), Gaps = 29/141 (20%)
Query: 103 CPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQ--VNGRWSGQTAICD- 159
CP P F NG R YNV ++F C GY L G TCQ N W C+
Sbjct: 2123 CPDPEPFANGIV--RGAGYNVGQSVTFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKCEV 2180
Query: 160 ---------NGAGYCSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGS 210
NG Y +PG P S +T G+ L S +
Sbjct: 2181 PCGGNITSSNGTVY--SPGFP---SPYSSSQDCVWLITVPIGHGVRLNLSLLQ------- 2228
Query: 211 WSGTEPSCQDSFMYDTPQEVA 231
TEPS ++D PQ+ A
Sbjct: 2229 ---TEPSGDFITIWDGPQQTA 2246
Score = 39.7 bits (91), Expect = 0.011
Identities = 23/60 (38%), Positives = 30/60 (50%), Gaps = 6/60 (10%)
Query: 165 CSNPG-IPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEG----GSWSGTEPSCQ 219
C NPG +P G ++ GS + L D V Y C+ G L G TC G +W PSC+
Sbjct: 139 CGNPGRLPNGIQQ-GSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSCR 197
Score = 38.9 bits (89), Expect = 0.018
Identities = 19/56 (33%), Positives = 28/56 (50%), Gaps = 2/56 (3%)
Query: 165 CSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGS--WSGTEPSC 218
C P +P + + G Q+ + D++T+ C G L G+ R TC G WS P C
Sbjct: 1039 CEEPEVPAYSIRKGLQFGVGDTLTFSCFPGYRLEGTARITCLGGRRRLWSSPLPRC 1094
Score = 38.9 bits (89), Expect = 0.018
Identities = 18/60 (30%), Positives = 26/60 (43%), Gaps = 2/60 (3%)
Query: 161 GAGYCSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEG--GSWSGTEPSC 218
G C P +P K G +Y + D V++ C G L+G +C G W+ P C
Sbjct: 1905 GLSSCPEPAVPSNGVKTGERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPPPLC 1964
Score = 38.1 bits (87), Expect = 0.031
Identities = 17/57 (29%), Positives = 27/57 (47%), Gaps = 3/57 (5%)
Query: 165 CSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTC---QEGGSWSGTEPSC 218
C++PGIP + G + DS + C G L+GS +C + W + P+C
Sbjct: 1385 CNDPGIPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPSPPTC 1441
Score = 37.7 bits (86), Expect = 0.040
Identities = 24/65 (36%), Positives = 32/65 (49%), Gaps = 6/65 (9%)
Query: 159 DNGAGYCSNPG-IPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGS----WSG 213
+N C +PG I GTR VGS +L SVTY+C G + G+ +C G W+
Sbjct: 1552 ENPRESCFDPGSIKNGTR-VGSDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNN 1610
Query: 214 TEPSC 218
P C
Sbjct: 1611 PRPVC 1615
Score = 36.6 bits (83), Expect = 0.090
Identities = 17/59 (28%), Positives = 29/59 (49%), Gaps = 2/59 (3%)
Query: 103 CPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNG--RWSGQTAICD 159
CP P N E + +N+ D + + C G+TL G+ TC++ ++ G IC+
Sbjct: 2294 CPPPTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGNEILTCKLGTYLQFEGPPPICE 2352
Score = 35.8 bits (81), Expect = 0.15
Identities = 18/59 (30%), Positives = 32/59 (54%), Gaps = 4/59 (6%)
Query: 165 CSNPGIPIGTRKVGSQYRLEDSVTYHCSRG-LTLRGSQRRTC--QEGG-SWSGTEPSCQ 219
C +PG+P+ ++ G +L S+++ C G L +GS+ TC +EG W+ C+
Sbjct: 691 CPDPGVPVNGKRFGDSLQLGSSISFLCDEGFLGTQGSETITCVLKEGSVVWNSAVLRCE 749
Score = 35.4 bits (80), Expect = 0.20
Identities = 24/79 (30%), Positives = 33/79 (41%), Gaps = 12/79 (15%)
Query: 103 CPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVN--GRWSGQTAIC-- 158
CP P NG Y V+D +SF C GY L+G A+ +C RW+ +C
Sbjct: 1909 CPEPAVPSNGV--KTGERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPPPLCIA 1966
Query: 159 ------DNGAGYCSNPGIP 171
+ G +PG P
Sbjct: 1967 QCGGTVEEMEGVILSPGFP 1985
Score = 33.5 bits (75), Expect = 0.76
Identities = 19/57 (33%), Positives = 27/57 (47%), Gaps = 3/57 (5%)
Query: 165 CSNPGIPIGTRKVGSQYRLE-DSVTYHCSRGLTLRGSQRRTCQEG--GSWSGTEPSC 218
C +PG P KV + SV++ C G +LRGS+ C G +W P+C
Sbjct: 1211 CEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEELLCLSGERRTWDRPLPTC 1267
Score = 32.7 bits (73), Expect = 1.3
Identities = 16/41 (39%), Positives = 22/41 (53%), Gaps = 4/41 (9%)
Query: 121 YNVSDEISFHCYDGYTLRGSANRTCQVNGR---WSGQTAIC 158
+ V D ++F C+ GY L G+A TC + GR WS C
Sbjct: 1055 FGVGDTLTFSCFPGYRLEGTARITC-LGGRRRLWSSPLPRC 1094
Score = 31.6 bits (70), Expect = 2.9
Identities = 22/78 (28%), Positives = 30/78 (38%), Gaps = 10/78 (12%)
Query: 102 HCPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICD-- 159
HC P NG+ Y V ++F C GYTL C+ N +WS C+
Sbjct: 866 HCLDPGIPVNGQRHGNDFY--VGALVTFSCDSGYTLSDGEPLECEPNFQWSRALPSCEAL 923
Query: 160 ------NGAGYCSNPGIP 171
+G +PG P
Sbjct: 924 CGGFIQGSSGTILSPGFP 941
Score = 30.8 bits (68), Expect = 4.9
Identities = 21/83 (25%), Positives = 32/83 (38%), Gaps = 15/83 (18%)
Query: 103 CPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTC----QVNGRWSGQTAIC 158
CP P E G+ + + + F C +GY L+GS TC + WS +C
Sbjct: 343 CPDPGIPERGKRLGSD--FRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVC 400
Query: 159 ---------DNGAGYCSNPGIPI 172
+G ++P PI
Sbjct: 401 RARMCDAHLRGPSGIITSPNFPI 423
Score = 30.4 bits (67), Expect = 6.4
Identities = 12/38 (31%), Positives = 18/38 (47%)
Query: 121 YNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAIC 158
++ D + F C + L G TCQ N +WS + C
Sbjct: 537 FHHGDTLKFECQPAFELVGQKAITCQKNNQWSAKKPGC 574
>gi|4506115 protein C [Homo sapiens]
Length = 461
Score = 79.7 bits (195), Expect = 9e-15
Identities = 68/235 (28%), Positives = 101/235 (42%), Gaps = 43/235 (18%)
Query: 494 PWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDKEHSIKVSVGGE--------K 545
PWQ V+ SK +C ++ +VLTAAHC D+ + V +G +
Sbjct: 224 PWQV---VLLDSKKKLACGAVLIHPSWVLTAAHCM---DESKKLLVRLGEYDLRRWEKWE 277
Query: 546 RDLEIEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEGTTR 605
DL+I+ V HPNY+ + D D+AL+ L QTI PICLP + R
Sbjct: 278 LDLDIKEVFVHPNYSKSTT---------DNDIALLHLAQPATLSQTIVPICLPDSGLAER 328
Query: 606 ALRLPPTTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERDAQYAPG 665
L Q +E L+ + S EK+ R ++ N K P
Sbjct: 329 ELN-------QAGQETLVTGWG----YHSSREKEAKRNRTFVLNFIK-------IPVVPH 370
Query: 666 YDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVISWG 720
+ + +S +V+ LC G + D C GDSGGP++ + VG++SWG
Sbjct: 371 NECSEVMSNMVSENMLCAGILGDRQD--ACEGDSGGPMVASFHGTWFLVGLVSWG 423
>gi|110815798 ovochymase 1 [Homo sapiens]
Length = 1134
Score = 79.0 bits (193), Expect = 2e-14
Identities = 63/240 (26%), Positives = 105/240 (43%), Gaps = 48/240 (20%)
Query: 491 HKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDKEHSIKVSVGGEKRDLEI 550
H PWQ + + G C GA+++ ++LTAAHC + + S + G R+L+
Sbjct: 584 HCWPWQVGLRFL----GDYQCGGAIINPVWILTAAHCVQLKNNPLSWTIIAGDHDRNLKE 639
Query: 551 EV--------VLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEG 602
++ H ++N YD D+ALI+L + L+Y +RP+CLP +
Sbjct: 640 STEQVRRAKHIIVHEDFNTLS---------YDSDIALIQLSSPLEYNSVVRPVCLPHS-- 688
Query: 603 TTRALRLPPTTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERDAQY 662
A L + C + A A + + + + +EV CE
Sbjct: 689 ---AEPLFSSEICAVTGWGSISADGGLASRLQQIQVHVLEREV----------CEHTYYS 735
Query: 663 A-PGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIV-HKRSRFIQVGVISWG 720
A PG +T + +C G + + + C+GDSGGPL+ H+ F+ G++SWG
Sbjct: 736 AHPG---------GITEKMIC-AGFAASGEKDFCQGDSGGPLVCRHENGPFVLYGIVSWG 785
Score = 70.9 bits (172), Expect = 4e-12
Identities = 62/238 (26%), Positives = 101/238 (42%), Gaps = 50/238 (21%)
Query: 494 PWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCF-----------TVDDKEHSIKVSVG 542
PWQ + S H C G+++ E V+TAAHC TV E+S+
Sbjct: 59 PWQVSLK----SDEHHFCGGSLIQEDRVVTAAHCLDSLSEKQLKNITVTSGEYSL-FQKD 113
Query: 543 GEKRDLEIEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEG 602
+++++ + ++ HP YN E+ D+AL+ LK+K+K+G ++PICLP ++
Sbjct: 114 KQEQNIPVSKIITHPEYNSR--------EYMSPDIALLYLKHKVKFGNAVQPICLPDSDD 165
Query: 603 TTRALRLPPTTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERDAQY 662
++ P C L + K SE L E+ I + + +
Sbjct: 166 -----KVEPGILC-------LSSGWGKISKTSEYSNVLQEMELPIMDDRACNTVLKSMNL 213
Query: 663 APGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSR-FIQVGVISW 719
P + LC G P + C+GDSGGPL+ + +I G+ SW
Sbjct: 214 PP-----------LGRTMLCAG--FPDWGMDACQGDSGGPLVCRRGGGIWILAGITSW 258
>gi|4503625 coagulation factor X preproprotein [Homo sapiens]
Length = 488
Score = 77.8 bits (190), Expect = 4e-14
Identities = 59/233 (25%), Positives = 104/233 (44%), Gaps = 45/233 (19%)
Query: 494 PWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHC------FTVDDKEHSIKVSVGGEKRD 547
PWQA + + ++G C G ++SE+++LTAAHC F V + + + GGE
Sbjct: 247 PWQALL-INEENEGF--CGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGEAVH 303
Query: 548 LEIEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEGTTRAL 607
E+EVV+ H + E YD+D+A+++LK + + + P CLP +
Sbjct: 304 -EVEVVIKHNRFT---------KETYDFDIAVLRLKTPITFRMNVAPACLPERDWA---- 349
Query: 608 RLPPTTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERDAQYAPGYD 667
+T QK ++ E+ ++ TR ++ + SC+ + +
Sbjct: 350 ----ESTLMTQKTGIVSGFG----RTHEKGRQSTRLKMLEVPYVDRNSCKLSSSF----- 396
Query: 668 KVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVISWG 720
++T C G + D C+GDSGGP + + + G++SWG
Sbjct: 397 -------IITQNMFCAGYDTKQED--ACQGDSGGPHVTRFKDTYFVTGIVSWG 440
>gi|145701030 transmembrane protease, serine 4 isoform 3 [Homo
sapiens]
Length = 432
Score = 76.3 bits (186), Expect = 1e-13
Identities = 70/241 (29%), Positives = 106/241 (43%), Gaps = 64/241 (26%)
Query: 494 PWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDKEHSIKVSVGGEKRD------ 547
PWQ I K H C G+++ ++VLTAAHCF + KV G +K
Sbjct: 212 PWQVSIQY---DKQHV-CGGSILDPHWVLTAAHCFRKHTDVFNWKVRAGSDKLGSFPSLA 267
Query: 548 -LEIEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEGTTRA 606
+I ++ F+P Y P+ D D+AL+KL+ L + T+RPICLP +
Sbjct: 268 VAKIIIIEFNPMY----------PK--DNDIALMKLQFPLTFSGTVRPICLPFFD----- 310
Query: 607 LRLPPTTTCQQQKEELLPAQDIKAL---FVSEEEKK----LTRKEVYIKNGDKKGSCERD 659
EEL PA + + F + K L + V + + + C D
Sbjct: 311 -------------EELTPATPLWIIGWGFTKQNGGKMSDILLQASVQVIDSTR---CNAD 354
Query: 660 AQYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVISW 719
Y VT + +C G P +TC+GDSGGPL +++ ++ VG++SW
Sbjct: 355 DAY----------QGEVTEKMMCAG--IPEGGVDTCQGDSGGPL-MYQSDQWHVVGIVSW 401
Query: 720 G 720
G
Sbjct: 402 G 402
>gi|15451940 transmembrane protease, serine 4 isoform 1 [Homo
sapiens]
Length = 437
Score = 76.3 bits (186), Expect = 1e-13
Identities = 70/241 (29%), Positives = 106/241 (43%), Gaps = 64/241 (26%)
Query: 494 PWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDKEHSIKVSVGGEKRD------ 547
PWQ I K H C G+++ ++VLTAAHCF + KV G +K
Sbjct: 217 PWQVSIQY---DKQHV-CGGSILDPHWVLTAAHCFRKHTDVFNWKVRAGSDKLGSFPSLA 272
Query: 548 -LEIEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEGTTRA 606
+I ++ F+P Y P+ D D+AL+KL+ L + T+RPICLP +
Sbjct: 273 VAKIIIIEFNPMY----------PK--DNDIALMKLQFPLTFSGTVRPICLPFFD----- 315
Query: 607 LRLPPTTTCQQQKEELLPAQDIKAL---FVSEEEKK----LTRKEVYIKNGDKKGSCERD 659
EEL PA + + F + K L + V + + + C D
Sbjct: 316 -------------EELTPATPLWIIGWGFTKQNGGKMSDILLQASVQVIDSTR---CNAD 359
Query: 660 AQYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVISW 719
Y VT + +C G P +TC+GDSGGPL +++ ++ VG++SW
Sbjct: 360 DAY----------QGEVTEKMMCAG--IPEGGVDTCQGDSGGPL-MYQSDQWHVVGIVSW 406
Query: 720 G 720
G
Sbjct: 407 G 407
>gi|148806900 epidermis-specific serine protease-like protein [Homo
sapiens]
Length = 328
Score = 75.1 bits (183), Expect = 2e-13
Identities = 68/238 (28%), Positives = 105/238 (44%), Gaps = 45/238 (18%)
Query: 494 PWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDKEHSIKV-----SVGGEKRDL 548
PWQ + + C G++VSE +LTAAHC S V +VG ++ +
Sbjct: 40 PWQVSLHFDH----NFICGGSLVSERLILTAAHCIQPTWTTFSYTVWLGSITVGDSRKRV 95
Query: 549 EIEV--VLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEGTTRA 606
+ V ++ HP Y DVAL+KL +++ + I PICLP T+
Sbjct: 96 KYYVSKIVIHPKYQDTTA-----------DVALLKLSSQVTFTSAILPICLP---SVTKQ 141
Query: 607 LRLPP---TTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERDAQYA 663
L +PP T + KE S+ + +E + D++ +CE+ Y
Sbjct: 142 LAIPPFCWVTGWGKVKES------------SDRDYHSALQEAEVPIIDRQ-ACEQ--LYN 186
Query: 664 PGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVISWGV 721
P + + V+ +C G D +C+GDSGGPL H +IQ GV+SWG+
Sbjct: 187 PIGIFLPALEPVIKEDKICAGDTQNMKD--SCKGDSGGPLSCHIDGVWIQTGVVSWGL 242
>gi|187960042 selectin E precursor [Homo sapiens]
Length = 610
Score = 73.6 bits (179), Expect = 7e-13
Identities = 47/166 (28%), Positives = 72/166 (43%), Gaps = 19/166 (11%)
Query: 62 CPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEY-WPRSPY 120
C GF Q+ C S+G+W ++ T + CRA+ P +NG SP
Sbjct: 272 CEEGFELMGAQSLQCTSSGNWDN----EKPTCKAVTCRAVRQP-----QNGSVRCSHSPA 322
Query: 121 --YNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYC---SNP--GIPIG 173
+ +F C +G+ L+G A C G+W+ Q +C+ A C SNP G
Sbjct: 323 GEFTFKSSCNFTCEEGFMLQGPAQVECTTQGQWTQQIPVCE--AFQCTALSNPERGYMNC 380
Query: 174 TRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
+R S + C +G L+GS+R C G W +P+C+
Sbjct: 381 LPSASGSFRYGSSCEFSCEQGFVLKGSKRLQCGPTGEWDNEKPTCE 426
Score = 71.6 bits (174), Expect = 3e-12
Identities = 50/174 (28%), Positives = 71/174 (40%), Gaps = 12/174 (6%)
Query: 47 GSFRLLQEGQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRP 106
GSFR G + E+ C GF + C TG W ++ T C A+H P P
Sbjct: 386 GSFRY---GSSCEFSCEQGFVLKGSKRLQCGPTGEWDN----EKPTCEAVRCDAVHQP-P 437
Query: 107 HDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCS 166
+ P + +F C +G+ L GS C G+W+ + C CS
Sbjct: 438 KGLVRCAHSPIGEF-TYKSSCAFSCEEGFELHGSTQLECTSQGQWTEEVPSCQ--VVKCS 494
Query: 167 NPGIPIGTRKVGSQYRLEDSVT-YHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
+ +P S + +V + C G TL GS RTC G WSG P+C+
Sbjct: 495 SLAVPGKINMSCSGEPVFGTVCKFACPEGWTLNGSAARTCGATGHWSGLLPTCE 548
Score = 58.9 bits (141), Expect = 2e-08
Identities = 39/171 (22%), Positives = 65/171 (38%), Gaps = 30/171 (17%)
Query: 62 CPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENG--EYWPRSP 119
C G+ P ++T C S+G WS C + C + NG E +
Sbjct: 210 CDRGYLPSSMETMQCMSSGEWS---------APIPACNVVECDAVTNPANGFVECFQNPG 260
Query: 120 YYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAIC-----------DNGAGYCSNP 168
+ + +F C +G+ L G+ + C +G W + C NG+ CS+
Sbjct: 261 SFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTCKAVTCRAVRQPQNGSVRCSHS 320
Query: 169 GIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
P G ++ + S + C G L+G + C G W+ P C+
Sbjct: 321 --PAG------EFTFKSSCNFTCEEGFMLQGPAQVECTTQGQWTQQIPVCE 363
Score = 47.4 bits (111), Expect = 5e-05
Identities = 39/163 (23%), Positives = 56/163 (34%), Gaps = 34/163 (20%)
Query: 71 VQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEYWPRSPYYNVS--DEIS 128
+ TC+ +S LK + + C A+ P E+G P N S S
Sbjct: 158 INNYTCKCDPGFSGLKCE-----QIVNCTALESP-----EHGSLVCSHPLGNFSYNSSCS 207
Query: 129 FHCYDGYTLRGSANRTCQVNGRWSGQTAICD-----------NGAGYC-SNPGIPIGTRK 176
C GY C +G WS C+ NG C NPG
Sbjct: 208 ISCDRGYLPSSMETMQCMSSGEWSAPIPACNVVECDAVTNPANGFVECFQNPG------- 260
Query: 177 VGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
+ + T+ C G L G+Q C G+W +P+C+
Sbjct: 261 ---SFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTCK 300
>gi|54792123 complement component (3d/Epstein Barr virus) receptor 2
isoform 1 [Homo sapiens]
Length = 1092
Score = 73.6 bits (179), Expect = 7e-13
Identities = 54/218 (24%), Positives = 90/218 (41%), Gaps = 21/218 (9%)
Query: 46 GGSFRLLQEGQALEYVCPSG------FYPYPVQTRTCRST----GSWSTLKTQDQKTVRK 95
G S G + Y C G F T C S G+WS + ++
Sbjct: 540 GSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLA 599
Query: 96 AECRAIHCPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQT 155
+C +H + E +PY+ +D ++F CY G+TL+GS+ C+ + W +
Sbjct: 600 VQCSHVHIANGYKISGKE----APYF-YNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEI 654
Query: 156 AICDNGAGYCSNPGIPIGTRKVGSQYRLEDSVT--YHCSRGLTLRGSQRRTCQEGGSWSG 213
+C+ G S PG+ G G+ +T Y C G L G++ C G+WS
Sbjct: 655 PVCEKGCQ--SPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSP 712
Query: 214 TEPSCQDSFMYDTPQEVAEAFLSSLTETIEGVDAEDGH 251
+ P C+++ + Q + E S E + +DG+
Sbjct: 713 SAPRCEETCQH-VRQSLQELPAGSRVELV-NTSCQDGY 748
Score = 60.8 bits (146), Expect = 4e-09
Identities = 43/182 (23%), Positives = 71/182 (39%), Gaps = 26/182 (14%)
Query: 46 GGSFRLLQEGQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPR 105
GG+ G ++Y C G+ ++ C +G+WS + ++T + P
Sbjct: 674 GGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEETCQHVRQSLQELPA 733
Query: 106 PHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQ--VNGRWSGQTAICDNGAG 163
E ++ C DGY L G A + CQ NG W + +C
Sbjct: 734 GSRVEL---------------VNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCK--VI 776
Query: 164 YCSNPGIPIGTRKVG---SQYRLEDSVTYHCSRGLTLRGSQRRTCQEG----GSWSGTEP 216
+C P + + + G + + V+Y C +G L G ++ C+ GSWSG P
Sbjct: 777 HCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSP 836
Query: 217 SC 218
C
Sbjct: 837 QC 838
Score = 60.5 bits (145), Expect = 6e-09
Identities = 36/145 (24%), Positives = 58/145 (40%), Gaps = 9/145 (6%)
Query: 77 RSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYT 136
+ TG+WS + + + A+ CP P + Y +D + F C G+T
Sbjct: 330 QKTGTWSGPAPRCELSTS-----AVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFT 384
Query: 137 LRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGTRKVGSQYRLE--DSVTYHCSRG 194
L+GS C G W +C+ + P I G ++ R + S+ Y C+ G
Sbjct: 385 LKGSKQIRCNAQGTWEPSAPVCEKECQ--APPNILNGQKEDRHMVRFDPGTSIKYSCNPG 442
Query: 195 LTLRGSQRRTCQEGGSWSGTEPSCQ 219
L G + C G W+ P C+
Sbjct: 443 YVLVGEESIQCTSEGVWTPPVPQCK 467
Score = 57.4 bits (137), Expect = 5e-08
Identities = 45/174 (25%), Positives = 62/174 (35%), Gaps = 13/174 (7%)
Query: 55 GQALEYVCPSGFYPYPVQTRTCRST----GSWSTLKTQDQKTVRKAECRAIHCPRPHDFE 110
G + Y C GFY + CRS GSWS Q ++ CP P
Sbjct: 800 GNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPP-----VTRCPNPEVKH 854
Query: 111 NGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGA--GYCSNP 168
+ Y+ +D + C G+ + GS C + W C A G P
Sbjct: 855 GYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPP 914
Query: 169 GIPIGTRKVGSQYRLED--SVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQD 220
P G G+ R S+ Y C +G L G C G+WS P C++
Sbjct: 915 KTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKE 968
Score = 54.3 bits (129), Expect = 4e-07
Identities = 45/178 (25%), Positives = 71/178 (39%), Gaps = 23/178 (12%)
Query: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEY 114
G ++ Y C SG+ + C S+G WS + T +A C+++ F NG+
Sbjct: 176 GLSVTYSCESGYLLVGEKIINCLSSGKWSAVPP----TCEEARCKSLG-----RFPNGKV 226
Query: 115 WPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGT 174
P V +F C +GY L+G + C + G+ T + +C +P +
Sbjct: 227 -KEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKMPVCEEIFCPSPPPILNG 285
Query: 175 RKVG---SQYRLEDSVTYHCSR------GLTLRGSQRRTC----QEGGSWSGTEPSCQ 219
R +G + VTY C L G C Q+ G+WSG P C+
Sbjct: 286 RHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCE 343
Score = 53.9 bits (128), Expect = 5e-07
Identities = 48/184 (26%), Positives = 72/184 (39%), Gaps = 32/184 (17%)
Query: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEY 114
G +++Y C G+ ++ C S G W+ Q + +A R + H F
Sbjct: 432 GTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQHQF----- 486
Query: 115 WPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGT 174
V +++ C +GY L GS + CQ W + +C C P +
Sbjct: 487 --------VRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEIT--CPPPPVIYNG 536
Query: 175 RKVGSQYRLED-----SVTYHCSRG------LTLRGSQRRTC----QEGGSWSGTEPSCQ 219
GS LED +VTY C+ G +L G C QE G+WSG P C+
Sbjct: 537 AHTGSS--LEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCK 594
Query: 220 DSFM 223
S +
Sbjct: 595 LSLL 598
Score = 50.1 bits (118), Expect = 8e-06
Identities = 29/115 (25%), Positives = 45/115 (39%), Gaps = 12/115 (10%)
Query: 46 GGSFRLLQEGQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPR 105
GG+ G ++ Y C G+ C G+WS C+ ++C
Sbjct: 923 GGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQ---------PAPHCKEVNCSS 973
Query: 106 PHDFENGEYW--PRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAIC 158
P D + + PR Y ++ C DGY L GS CQ + +W+ A+C
Sbjct: 974 PADMDGIQKGLEPRK-MYQYGAVVTLECEDGYMLEGSPQSQCQSDHQWNPPLAVC 1027
Score = 48.5 bits (114), Expect = 2e-05
Identities = 43/178 (24%), Positives = 64/178 (35%), Gaps = 19/178 (10%)
Query: 55 GQALEYVCPSGFYPYPVQTRTC----RSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFE 110
G + Y C F ++ C + G+W K K E + P
Sbjct: 44 GTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWD-------KPAPKCEYFNKYSSCPEPIV 96
Query: 111 NGEYWPR-SPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPG 169
G Y R S Y D ++F C +++ G+ + CQ N W P
Sbjct: 97 PGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPTRLPTCVSVFPLECPA 156
Query: 170 IPI------GTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDS 221
+P+ + VGS SVTY C G L G + C G WS P+C+++
Sbjct: 157 LPMIHNGHHTSENVGS-IAPGLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCEEA 213
Score = 47.4 bits (111), Expect = 5e-05
Identities = 45/196 (22%), Positives = 77/196 (39%), Gaps = 23/196 (11%)
Query: 41 GVEIKGGSFRLLQEGQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRA 100
G +I+G + + G ++ + C + F ++ C++ W + +V EC A
Sbjct: 99 GYKIRGST--PYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPTRLPTCVSVFPLECPA 156
Query: 101 IHCPRPHDFENGEYWPRSPYYNVSD-----EISFHCYDGYTLRGSANRTCQVNGRWSGQT 155
+ P H NG + NV +++ C GY L G C +G+WS
Sbjct: 157 L--PMIH---NGHHTSE----NVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKWSAVP 207
Query: 156 AICDNGAGYCSNPG-IPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTC---QEGGSW 211
C+ C + G P G K R+ + + C G L+G C +G +W
Sbjct: 208 PTCEEAR--CKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAW 265
Query: 212 SGTEPSCQDSFMYDTP 227
+ P C++ F P
Sbjct: 266 T-KMPVCEEIFCPSPP 280
Score = 45.8 bits (107), Expect = 1e-04
Identities = 35/123 (28%), Positives = 46/123 (37%), Gaps = 6/123 (4%)
Query: 101 IHCPRPHDFENGEYWPRS-PYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICD 159
I CP P NG + + ++ I + C GY L G A C G WS C
Sbjct: 908 IGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCK 967
Query: 160 NGAGYCSNPGIPIGTRK---VGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEP 216
CS+P G +K Y+ VT C G L GS + CQ W+
Sbjct: 968 EVN--CSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQWNPPLA 1025
Query: 217 SCQ 219
C+
Sbjct: 1026 VCR 1028
>gi|4506153 prostasin preproprotein [Homo sapiens]
Length = 343
Score = 72.4 bits (176), Expect = 1e-12
Identities = 65/254 (25%), Positives = 104/254 (40%), Gaps = 60/254 (23%)
Query: 494 PWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDKEHSIKVSVGGEKRD------ 547
PWQ I+ +G C G++VSE +VL+AAHCF + + + +V +G + D
Sbjct: 57 PWQVSITY----EGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQLDSYSEDA 112
Query: 548 --LEIEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEGT-- 603
++ ++ HP+Y G + D+AL++L + + + IRPICLP +
Sbjct: 113 KVSTLKDIIPHPSYLQEGSQG---------DIALLQLSRPITFSRYIRPICLPAANASFP 163
Query: 604 -------TRALRLPPTTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSC 656
T + P+ + K P Q ++ +S E T +Y
Sbjct: 164 NGLHCTVTGWGHVAPSVSLLTPK----PLQQLEVPLISRE----TCNCLY---------- 205
Query: 657 ERDAQYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGV 716
D + V +C G V D C+GDSGGPL + G+
Sbjct: 206 --------NIDAKPEEPHFVQEDMVCAGYVEGGKD--ACQGDSGGPLSCPVEGLWYLTGI 255
Query: 717 ISWGVVDVCKNQKR 730
+SWG D C + R
Sbjct: 256 VSWG--DACGARNR 267
>gi|4502503 complement component 4 binding protein, alpha chain
precursor [Homo sapiens]
Length = 597
Score = 69.3 bits (168), Expect = 1e-11
Identities = 48/198 (24%), Positives = 77/198 (38%), Gaps = 25/198 (12%)
Query: 43 EIKGGSFRL---LQEGQALEYVCPSGFYPYPVQTRTC----RSTGSWSTLKTQDQKTVRK 95
E++ G + L G +E+ C GF+ T C R G WS Q
Sbjct: 118 ELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVG-WSHPLPQ------- 169
Query: 96 AECRAIHCPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVN----GRW 151
C + C P D NG + +Y +++ C ++L G A+ +C V G W
Sbjct: 170 --CEIVKCKPPPDIRNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVW 227
Query: 152 SGQTAICDNGAGYCSNPGIPIG--TRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGG 209
C+ C P + G G Y +D++ + C +G LRGS C
Sbjct: 228 RPSPPTCEKIT--CRKPDVSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHCDADS 285
Query: 210 SWSGTEPSCQDSFMYDTP 227
W+ + P+C+ + + P
Sbjct: 286 KWNPSPPACEPNSCINLP 303
Score = 58.5 bits (140), Expect = 2e-08
Identities = 44/154 (28%), Positives = 60/154 (38%), Gaps = 19/154 (12%)
Query: 76 CRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEYWPRSPYYNVSDEISFHCYDGY 135
C+ G+WS R C I C P +G Y S Y +EI + C GY
Sbjct: 409 CQGDGTWSP---------RTPSCGDI-CNFPPKIAHGHYKQSSSYSFFKEEIIYECDKGY 458
Query: 136 TLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGTRKVG-SQYRLEDSVTYHCSRG 194
L G A +C + WS C C P + G V QY ++VT C G
Sbjct: 459 ILVGQAKLSCSYS-HWSAPAPQC---KALCRKPELVNGRLSVDKDQYVEPENVTIQCDSG 514
Query: 195 LTLRGSQRRTCQEGGSWSGTEPSCQDSFMYDTPQ 228
+ G Q TC +W P C+ ++TP+
Sbjct: 515 YGVVGPQSITCSGNRTWYPEVPKCE----WETPE 544
Score = 57.4 bits (137), Expect = 5e-08
Identities = 48/175 (27%), Positives = 68/175 (38%), Gaps = 23/175 (13%)
Query: 55 GQALEYVCPSGFY-PYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGE 113
G L+Y C G+ + QT TC S G W V C C P + NG+
Sbjct: 74 GTTLKYTCLPGYVRSHSTQTLTCNSDGEW----------VYNTFCIYKRCRHPGELRNGQ 123
Query: 114 YWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGR---WSGQTAICDNGAGYCSNPGI 170
++ + +I F C +G+ L GS C+V R WS C+ C P
Sbjct: 124 VEIKTD-LSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSHPLPQCE--IVKCKPPPD 180
Query: 171 PIGTRKVGSQ--YRLEDSVTYHCSRGLTLRGSQRRTC----QEGGSWSGTEPSCQ 219
R G + Y SVTY C +L G +C + G W + P+C+
Sbjct: 181 IRNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVWRPSPPTCE 235
>gi|157419154 selectin P precursor [Homo sapiens]
Length = 830
Score = 69.3 bits (168), Expect = 1e-11
Identities = 51/194 (26%), Positives = 77/194 (39%), Gaps = 11/194 (5%)
Query: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEY 114
G + C +GF C ++G WS K + + CP G
Sbjct: 595 GSTCHFSCDNGFKLEGPNNVECTTSGRWSATPPTC-KGIASLPTPGVQCPALTTPGQGTM 653
Query: 115 WPRSP--YYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCS----NP 168
+ R + + F C G+TL G + +C+ +G+W+ T C A CS N
Sbjct: 654 YCRHHPGTFGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPACR--AVKCSELHVNK 711
Query: 169 GIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDSFMYDTPQ 228
I + + + ++HC G L GS + CQE G WS T P+CQ + T Q
Sbjct: 712 PIAMNCSNLWGNFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTCQAGPL--TIQ 769
Query: 229 EVAEAFLSSLTETI 242
E F ++ TI
Sbjct: 770 EALTYFGGAVASTI 783
Score = 62.8 bits (151), Expect = 1e-09
Identities = 43/174 (24%), Positives = 65/174 (37%), Gaps = 23/174 (13%)
Query: 59 EYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENG--EYWP 116
+++C G+ + C +G W T C AI CP E G +
Sbjct: 537 QFICDEGYSLSGPERLDCTRSGRW---------TDSPPMCEAIKCPELFAPEQGSLDCSD 587
Query: 117 RSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGI---PIG 173
+NV F C +G+ L G N C +GRWS C G PG+ +
Sbjct: 588 TRGEFNVGSTCHFSCDNGFKLEGPNNVECTTSGRWSATPPTC-KGIASLPTPGVQCPALT 646
Query: 174 TRKVGSQY--------RLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
T G+ Y + + C+ G TL G +C+ G W+ P+C+
Sbjct: 647 TPGQGTMYCRHHPGTFGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPACR 700
Score = 61.2 bits (147), Expect = 3e-09
Identities = 42/174 (24%), Positives = 65/174 (37%), Gaps = 17/174 (9%)
Query: 60 YVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEYWPRSP 119
+ C G C +TG+W+++ EC+AI C +NG P
Sbjct: 476 FTCNEGLLLVGASVLQCLATGNWNSVPP---------ECQAIPCTPLLSPQNGTMTCVQP 526
Query: 120 YYNVS--DEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIP----IG 173
+ S F C +GY+L G C +GRW+ +C+ A C P +
Sbjct: 527 LGSSSYKSTCQFICDEGYSLSGPERLDCTRSGRWTDSPPMCE--AIKCPELFAPEQGSLD 584
Query: 174 TRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDSFMYDTP 227
++ + + + C G L G C G WS T P+C+ TP
Sbjct: 585 CSDTRGEFNVGSTCHFSCDNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTP 638
Score = 58.2 bits (139), Expect = 3e-08
Identities = 43/172 (25%), Positives = 68/172 (39%), Gaps = 19/172 (11%)
Query: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWST-LKTQDQKTVRKAECRAIHCPRPHDFENG- 112
G + ++ C G+ + C +G WS L T C AI C +G
Sbjct: 347 GSSCKFECQPGYRVRGLDMLRCIDSGHWSAPLPT----------CEAISCEPLESPVHGS 396
Query: 113 -EYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIP 171
+ P + SF C +G+ LRG+ C G+W+ +C A C + +P
Sbjct: 397 MDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQ--ALQCQDLPVP 454
Query: 172 IGTRKVGSQ----YRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
R S +R + ++ C+ GL L G+ C G+W+ P CQ
Sbjct: 455 NEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQ 506
Score = 53.9 bits (128), Expect = 5e-07
Identities = 43/186 (23%), Positives = 64/186 (34%), Gaps = 17/186 (9%)
Query: 48 SFRLLQEGQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPH 107
S + Q + + C GF + C ++G W T C+A+ C
Sbjct: 278 SAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVW---------TAPAPVCKAVQCQHLE 328
Query: 108 DFENGEYWPRSPY--YNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYC 165
G P + F C GY +RG C +G WS C+ A C
Sbjct: 329 APSEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCIDSGHWSAPLPTCE--AISC 386
Query: 166 SNPGIPI-GTRKVGSQYRL---EDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDS 221
P+ G+ R + + ++ C+ G LRG+ C G W+ P CQ
Sbjct: 387 EPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQAL 446
Query: 222 FMYDTP 227
D P
Sbjct: 447 QCQDLP 452
Score = 49.3 bits (116), Expect = 1e-05
Identities = 26/103 (25%), Positives = 44/103 (42%), Gaps = 6/103 (5%)
Query: 121 YNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIP----IGTRK 176
++ + + SFHC DGY + G + C +G W+ + C A C IP +
Sbjct: 220 FSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQC--LAAQCPPLKIPERGNMTCLH 277
Query: 177 VGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
++ + S ++ C G L G + C G W+ P C+
Sbjct: 278 SAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAPVCK 320
>gi|168693643 decay accelerating factor for complement isoform 2
precursor [Homo sapiens]
Length = 440
Score = 66.6 bits (161), Expect = 8e-11
Identities = 55/179 (30%), Positives = 72/179 (40%), Gaps = 30/179 (16%)
Query: 55 GQALEYVCPSGFYPYPVQTR--TCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENG 112
G +EY C G+ P + TC WST C+ CP P + NG
Sbjct: 122 GTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEF---------CKKKSCPNPGEIRNG 172
Query: 113 EY-WPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNG---RWSGQTAICDNGAGYCSNP 168
+ P + + ISF C GY L GS + C ++G +WS C YC P
Sbjct: 173 QIDVPGGILFGAT--ISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREI--YCPAP 228
Query: 169 -----GIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTC---QEGGSWSGTEPSCQ 219
GI G R Y SVTY C++G T+ G C + G WSG P C+
Sbjct: 229 PQIDNGIIQGER---DHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECR 284
Score = 51.2 bits (121), Expect = 4e-06
Identities = 31/120 (25%), Positives = 52/120 (43%), Gaps = 13/120 (10%)
Query: 42 VEIKGGSFRLLQEGQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAI 101
+++ GG + G + + C +G+ + + C +GS Q + ECR I
Sbjct: 174 IDVPGG----ILFGATISFSCNTGYKLFGSTSSFCLISGS------SVQWSDPLPECREI 223
Query: 102 HCPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVN---GRWSGQTAIC 158
+CP P +NG +Y +++ C G+T+ G + C VN G WSG C
Sbjct: 224 YCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC 283
>gi|10835143 decay accelerating factor for complement isoform 1
preproprotein [Homo sapiens]
Length = 381
Score = 66.6 bits (161), Expect = 8e-11
Identities = 55/179 (30%), Positives = 72/179 (40%), Gaps = 30/179 (16%)
Query: 55 GQALEYVCPSGFYPYPVQTR--TCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENG 112
G +EY C G+ P + TC WST C+ CP P + NG
Sbjct: 122 GTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEF---------CKKKSCPNPGEIRNG 172
Query: 113 EY-WPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNG---RWSGQTAICDNGAGYCSNP 168
+ P + + ISF C GY L GS + C ++G +WS C YC P
Sbjct: 173 QIDVPGGILFGAT--ISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREI--YCPAP 228
Query: 169 -----GIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTC---QEGGSWSGTEPSCQ 219
GI G R Y SVTY C++G T+ G C + G WSG P C+
Sbjct: 229 PQIDNGIIQGER---DHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECR 284
Score = 51.2 bits (121), Expect = 4e-06
Identities = 31/120 (25%), Positives = 52/120 (43%), Gaps = 13/120 (10%)
Query: 42 VEIKGGSFRLLQEGQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAI 101
+++ GG + G + + C +G+ + + C +GS Q + ECR I
Sbjct: 174 IDVPGG----ILFGATISFSCNTGYKLFGSTSSFCLISGS------SVQWSDPLPECREI 223
Query: 102 HCPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVN---GRWSGQTAIC 158
+CP P +NG +Y +++ C G+T+ G + C VN G WSG C
Sbjct: 224 YCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC 283
>gi|156938340 transmembrane tryptase preproprotein [Homo sapiens]
Length = 321
Score = 66.6 bits (161), Expect = 8e-11
Identities = 63/233 (27%), Positives = 102/233 (43%), Gaps = 45/233 (19%)
Query: 494 PWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDKEHSIKVSVGGEKRDLEIEVV 553
PWQA + + R C G+++S +VLTAAHCF+ +V +G E+E+
Sbjct: 50 PWQASLRLRRV----HVCGGSLLSPQWVLTAAHCFSGSLNSSDYQVHLG------ELEIT 99
Query: 554 LFHPNYN-----INGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLP-CTEGTTRAL 607
L P+++ I +G P D+AL++L + I P+CLP ++ +
Sbjct: 100 L-SPHFSTVRQIILHSSPSGQPGTSG-DIALVELSVPVTLSSRILPVCLPEASDDFCPGI 157
Query: 608 RLPPTTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERDAQYAPGYD 667
R T ++ E LP + +EV + D + +C RD PG
Sbjct: 158 RCWVTGWGYTREGEPLPPP-------------YSLREVKVSVVDTE-TCRRDYP-GPG-- 200
Query: 668 KVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVISWG 720
++ P LC G + C+ DSGGPL+ ++Q G++SWG
Sbjct: 201 -----GSILQPDMLCARGPG-----DACQDDSGGPLVCQVNGAWVQAGIVSWG 243
>gi|33186882 testis serine protease 2 [Homo sapiens]
Length = 293
Score = 66.2 bits (160), Expect = 1e-10
Identities = 64/246 (26%), Positives = 105/246 (42%), Gaps = 50/246 (20%)
Query: 487 GTDYHKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDKEHSIKV---SVGG 543
G D + W ++SV +KG C G +V+ +VLTA HC + +S+K+ SV
Sbjct: 83 GVDAEEGRWPWQVSV--RTKGRHICGGTLVTATWVLTAGHCIS-SRFHYSVKMGDRSVYN 139
Query: 544 EKRDLEIEV--VLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPC-- 599
E + + V HP ++ D+AL++L++ + + I+PIC+P
Sbjct: 140 ENTSVVVSVQRAFVHPKFST--------VTTIRNDLALLQLQHPVNFTSNIQPICIPQEN 191
Query: 600 --TEGTTRALRLPPTTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCE 657
EG TR T +++K QD+ + EE C
Sbjct: 192 FQVEGRTRCWVTGWGKTPEREKLASEILQDVDQYIMCYEE------------------CN 233
Query: 658 RDAQYAPGYDKVKDISEVVTPRFLCTGGVSPYADP--NTCRGDSGGPLIVHKRSRFIQVG 715
+ Q A KD+ + G V Y + ++C+GDSGG L ++QVG
Sbjct: 234 KIIQKA--LSSTKDV--------IIKGMVCGYKEQGKDSCQGDSGGRLACEYNDTWVQVG 283
Query: 716 VISWGV 721
++SWG+
Sbjct: 284 IVSWGI 289
>gi|7019563 testes-specific protease 50 [Homo sapiens]
Length = 385
Score = 66.2 bits (160), Expect = 1e-10
Identities = 56/238 (23%), Positives = 96/238 (40%), Gaps = 42/238 (17%)
Query: 494 PWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDKEHSIKVS------VGGEKRD 547
PW + + G C G +++ +VLT AHC D +S++V + D
Sbjct: 125 PWMVSVR----ANGTHICAGTIIASQWVLTVAHCLIWRDVIYSVRVGSPWIDQMTQTASD 180
Query: 548 LEIEVVLFHPNYNINGKKEAGIPEFYDY-----DVALIKLKNKLKYGQTIRPICLPCTEG 602
+ + V+ H Y F+ + D+ L+KLK +LKY +RPICLP T+
Sbjct: 181 VPVLQVIMHSRYRAQ--------RFWSWVGQANDIGLLKLKQELKYSNYVRPICLPGTDY 232
Query: 603 TTRALRLPPTTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERDAQY 662
L + C L A + F + + KEV I N + C+ +
Sbjct: 233 V-----LKDHSRCTVTGWGLSKADGMWPQF-----RTIQEKEVIILNNKE---CD---NF 276
Query: 663 APGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVISWG 720
+ K+ + +++ + +C C +G PL+ + VG++SWG
Sbjct: 277 YHNFTKIPTLVQIIKSQMMCAEDTH---REKFCYELTGEPLVCSMEGTWYLVGLVSWG 331
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.135 0.419
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,377,568
Number of Sequences: 37866
Number of extensions: 1569585
Number of successful extensions: 4926
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 160
Number of HSP's successfully gapped in prelim test: 107
Number of HSP's that attempted gapping in prelim test: 3547
Number of HSP's gapped (non-prelim): 823
length of query: 764
length of database: 18,247,518
effective HSP length: 110
effective length of query: 654
effective length of database: 14,082,258
effective search space: 9209796732
effective search space used: 9209796732
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.