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Search of human proteins with 66954681
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|66954681 PRAME family member 13 [Homo sapiens]
(474 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|66954681 PRAME family member 13 [Homo sapiens] 964 0.0
gi|12738831 PRAME family member 1 [Homo sapiens] 931 0.0
gi|12738834 PRAME family member 2 [Homo sapiens] 887 0.0
gi|153792140 PRAME family member 14 [Homo sapiens] 830 0.0
gi|194306635 PRAME family member 19 [Homo sapiens] 553 e-157
gi|154800493 PRAME family member 22 [Homo sapiens] 552 e-157
gi|153791443 PRAME family member 18 [Homo sapiens] 549 e-156
gi|194018546 PRAME family member 10 [Homo sapiens] 547 e-156
gi|194306638 PRAME family member 3 [Homo sapiens] 546 e-155
gi|157426839 PRAME family member 17 [Homo sapiens] 544 e-155
gi|113865933 PRAME family member 16 [Homo sapiens] 542 e-154
gi|239741051 PREDICTED: similar to PRAME family member 10 [Homo ... 507 e-143
gi|239741055 PREDICTED: similar to PRAME family member 10 [Homo ... 506 e-143
gi|239741047 PREDICTED: PRAME family member 25-like [Homo sapiens] 469 e-132
gi|124249372 PRAME family member 12 [Homo sapiens] 464 e-131
gi|239741053 PREDICTED: similar to Putative PRAME family member ... 448 e-126
gi|59676587 PRAME family member 8 [Homo sapiens] 448 e-126
gi|59676593 PRAME family member 7 [Homo sapiens] 446 e-125
gi|153792112 PRAME family member 20 [Homo sapiens] 429 e-120
gi|153945800 PRAME family member 21 [Homo sapiens] 429 e-120
gi|148356236 PRAME family member 15 [Homo sapiens] 410 e-114
gi|61102721 PRAME family member 9 [Homo sapiens] 410 e-114
gi|61696142 PRAME family member 5 [Homo sapiens] 410 e-114
gi|58219004 PRAME family member 6 [Homo sapiens] 410 e-114
gi|239741045 PREDICTED: PRAME family member 23 [Homo sapiens] 407 e-114
gi|239741043 PREDICTED: PRAME family member 11 [Homo sapiens] 404 e-112
gi|59958373 PRAME family member 4 [Homo sapiens] 401 e-112
gi|46249373 preferentially expressed antigen in melanoma [Homo s... 358 6e-99
gi|46249371 preferentially expressed antigen in melanoma [Homo s... 358 6e-99
gi|46249369 preferentially expressed antigen in melanoma [Homo s... 358 6e-99
>gi|66954681 PRAME family member 13 [Homo sapiens]
Length = 474
Score = 964 bits (2491), Expect = 0.0
Identities = 474/474 (100%), Positives = 474/474 (100%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP
Sbjct: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW
Sbjct: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
Query: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL
Sbjct: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
Query: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS
Sbjct: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
Query: 241 RCHHSMSDNELEGRLVTKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL 300
RCHHSMSDNELEGRLVTKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL
Sbjct: 241 RCHHSMSDNELEGRLVTKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL 300
Query: 301 TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEGCQ 360
TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEGCQ
Sbjct: 301 TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEGCQ 360
Query: 361 IHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLRHTSGLSKLSLETYPAPEESLN 420
IHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLRHTSGLSKLSLETYPAPEESLN
Sbjct: 361 IHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLRHTSGLSKLSLETYPAPEESLN 420
Query: 421 SLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLCC 474
SLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLCC
Sbjct: 421 SLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLCC 474
>gi|12738831 PRAME family member 1 [Homo sapiens]
Length = 474
Score = 931 bits (2405), Expect = 0.0
Identities = 458/474 (96%), Positives = 464/474 (97%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAF RRHFQTLTVMVQAWP
Sbjct: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFSRRHFQTLTVMVQAWP 60
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW
Sbjct: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
Query: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
ALSCFPET SKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL
Sbjct: 121 ALSCFPETTSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
Query: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
CCSKLVNYLTPIK+LRKSLKIIYLNSIQ+LEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS
Sbjct: 181 CCSKLVNYLTPIKYLRKSLKIIYLNSIQELEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
Query: 241 RCHHSMSDNELEGRLVTKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL 300
RCHH SDNEL+GRLV KFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL
Sbjct: 241 RCHHYTSDNELQGRLVAKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL 300
Query: 301 TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEGCQ 360
TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASL+TLILEGCQ
Sbjct: 301 TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLKTLILEGCQ 360
Query: 361 IHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLRHTSGLSKLSLETYPAPEESLN 420
IHYSQLSAILP LS CSQLTTFYFGRNCMS+ ALKDLLRHTSGLSKLSLETYPAPEESLN
Sbjct: 361 IHYSQLSAILPALSRCSQLTTFYFGRNCMSIDALKDLLRHTSGLSKLSLETYPAPEESLN 420
Query: 421 SLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLCC 474
SLVRV+WEIF LRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLCC
Sbjct: 421 SLVRVNWEIFTPLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLCC 474
>gi|12738834 PRAME family member 2 [Homo sapiens]
Length = 474
Score = 887 bits (2292), Expect = 0.0
Identities = 439/474 (92%), Positives = 449/474 (94%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLF EAF RRHFQTLTVMVQAWP
Sbjct: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFREAFSRRHFQTLTVMVQAWP 60
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
FTCLPL SLMKTLHLE LKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW
Sbjct: 61 FTCLPLVSLMKTLHLEPLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
Query: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
ALSCFPE MSKRQTAEDCPR GEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL
Sbjct: 121 ALSCFPEAMSKRQTAEDCPRTGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
Query: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
CCSKLVNYLTPIK+LRKSLKIIY+NSI +LEI N WP LIRKL CYLKEMK L KLVFS
Sbjct: 181 CCSKLVNYLTPIKYLRKSLKIIYINSIGELEIHNTCWPHLIRKLYCYLKEMKTLCKLVFS 240
Query: 241 RCHHSMSDNELEGRLVTKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL 300
RCHH SDNELEG LVT+F+SVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL
Sbjct: 241 RCHHYTSDNELEGWLVTRFTSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL 300
Query: 301 TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEGCQ 360
T G LLEED+KCLSQ+PSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETL+LEGCQ
Sbjct: 301 TCGNLLEEDLKCLSQFPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLVLEGCQ 360
Query: 361 IHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLRHTSGLSKLSLETYPAPEESLN 420
IHYSQLSAILPGLS CSQLTTFYFG NCMS+ ALKDLLRHTSGLSKLSLETYPAPEESLN
Sbjct: 361 IHYSQLSAILPGLSCCSQLTTFYFGSNCMSIDALKDLLRHTSGLSKLSLETYPAPEESLN 420
Query: 421 SLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLCC 474
SLVRV+WEIF LRAELMCTLRE RQPKRIFIGPTPCPSCGSSPSEELELHLCC
Sbjct: 421 SLVRVNWEIFTPLRAELMCTLREFRQPKRIFIGPTPCPSCGSSPSEELELHLCC 474
>gi|153792140 PRAME family member 14 [Homo sapiens]
Length = 426
Score = 830 bits (2145), Expect = 0.0
Identities = 419/474 (88%), Positives = 421/474 (88%), Gaps = 48/474 (10%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP
Sbjct: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW
Sbjct: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
Query: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL
Sbjct: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
Query: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS
Sbjct: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
Query: 241 RCHHSMSDNELEGRLVTKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL 300
RC + +N LEL
Sbjct: 241 RCLQNPLEN------------------------------------------------LEL 252
Query: 301 TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEGCQ 360
TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEGCQ
Sbjct: 253 TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEGCQ 312
Query: 361 IHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLRHTSGLSKLSLETYPAPEESLN 420
IHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLL HTSGLSKLSLETYPAPEESLN
Sbjct: 313 IHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLCHTSGLSKLSLETYPAPEESLN 372
Query: 421 SLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLCC 474
SLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLCC
Sbjct: 373 SLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLCC 426
>gi|194306635 PRAME family member 19 [Homo sapiens]
Length = 479
Score = 553 bits (1425), Expect = e-157
Identities = 291/473 (61%), Positives = 343/473 (72%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
MS QAP RLLELAGQSLLRDQAL+IS ++ELPR L+ LF+EAF R + L VMVQAWP
Sbjct: 1 MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F CLPLGSLMKT LE L +++G+ LL QK RPRRWKLQVL++RDVDENFW W GA
Sbjct: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
Query: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
LSC PE MSKRQT EDCPR GE QPLKVF+D+CLKE DE L + WV RR VHL
Sbjct: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
Query: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
CC+K+VNY I + R L+ +Y +SIQ LEI NM WP ++ ++ YL +MKNLRKL S
Sbjct: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKNLRKLFIS 240
Query: 241 RCHHSMSDNELEGRLVTKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL 300
+ E +G+LV +FSSVFLRLE+LQ+L ++ I FF G+L+QLIRCL++PLE L L
Sbjct: 241 DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLAL 300
Query: 301 TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEGCQ 360
TYG L EED+KCL YPSL LK LNLS+ L I LEPL ALLEK+AA+L+TL L C
Sbjct: 301 TYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDCG 360
Query: 361 IHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLRHTSGLSKLSLETYPAPEESLN 420
I YS+L ILP LS CS LTTF F N SM LKDLLRHT LS LSLETYPAP ESL+
Sbjct: 361 IGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 420
Query: 421 SLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLC 473
+ RV E+ L+AELM LREVR+P RIF GP CP CG SP+E+LE + C
Sbjct: 421 NRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFC 473
>gi|154800493 PRAME family member 22 [Homo sapiens]
Length = 481
Score = 552 bits (1422), Expect = e-157
Identities = 291/474 (61%), Positives = 346/474 (72%), Gaps = 2/474 (0%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
MS+QAP RLLELAGQSLL DQAL+IS ++ELPR L+ PLF+EAF R + L VMVQAWP
Sbjct: 3 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F CLPLGSLMKT LE L +++G+ LL QK RPRRWKLQVL+LRDVDENFW W GA
Sbjct: 63 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSGAR 122
Query: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
LSC PE MSKRQT EDCPR GE QPLKVF+D+CLKE DE L + WV RRG VHL
Sbjct: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
Query: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
CC+K+VNY I + R L+ +Y +SIQ LEI NM WP +I + YL +M+NLRKL S
Sbjct: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSRYLSQMRNLRKLFIS 242
Query: 241 -RCHHSMSDNELEGRLVTKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLE 299
C + +S + E +LV +FSSV LRLE+LQ+L ++ + FF GHL+QLIRCL++PLE L
Sbjct: 243 DGCRYLLSSDSQE-QLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETLA 301
Query: 300 LTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEGC 359
LTYG+L + D+KCL +YPSL LK LNLS+ L I LEPL ALLEK+AA+L+TL L C
Sbjct: 302 LTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVDC 361
Query: 360 QIHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLRHTSGLSKLSLETYPAPEESL 419
I S+L ILP LS CS LTTF F N SM LKDLLRHT LS LSLETYPAP ESL
Sbjct: 362 GIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESL 421
Query: 420 NSLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLC 473
+ RV E+ L+AELM LREVR+PKRIF GP CP CG+SP+E+LE + C
Sbjct: 422 DDRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFC 475
>gi|153791443 PRAME family member 18 [Homo sapiens]
Length = 479
Score = 549 bits (1415), Expect = e-156
Identities = 290/473 (61%), Positives = 342/473 (72%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
MS QAP RLLELAGQSLLRDQAL+IS ++ELPR L+ LF+EAF R + L VMVQAWP
Sbjct: 1 MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F CLPLGSLMKT LE L +++G+ LL QK RPRRWKLQVL++RDVDENFW W GA
Sbjct: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
Query: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
LSC PE MSKRQT EDCPR GE QPLKVF+D+CLKE DE L + WV RR VHL
Sbjct: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
Query: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
CC+K+VNY I + R L+ +Y +SIQ LEI NM WP ++ ++ YL +MKNLRKL S
Sbjct: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKNLRKLFIS 240
Query: 241 RCHHSMSDNELEGRLVTKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL 300
+ E +G+LV +FSSVFLRLE+LQ+L ++ I FF G+L+QLIRCL++PLE L L
Sbjct: 241 DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLAL 300
Query: 301 TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEGCQ 360
TYG L EED+KCL YPSL LK LNLS+ L I LEPL ALLEK+AA+L+TL L C
Sbjct: 301 TYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDCG 360
Query: 361 IHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLRHTSGLSKLSLETYPAPEESLN 420
I S+L ILP LS CS LTTF F N SM LKDLLRHT LS LSLETYPAP ESL+
Sbjct: 361 IGDSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 420
Query: 421 SLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLC 473
+ RV E+ L+AELM LREVR+P RIF GP CP CG SP+E+LE + C
Sbjct: 421 NRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFC 473
>gi|194018546 PRAME family member 10 [Homo sapiens]
Length = 474
Score = 547 bits (1409), Expect = e-156
Identities = 283/473 (59%), Positives = 337/473 (71%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
MS+QAP RLLELAGQSLLR+Q L+I ++ELPR ++ +FMEAF R F+ L +MVQAWP
Sbjct: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F LPLGSLMKTLHLETL+A+L GL L+ QK RPRRWKLQVLDLRDVDENFW W GA
Sbjct: 61 FLSLPLGSLMKTLHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
Query: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
LSC PE MSKRQT EDCPRMGEHQPLKVFID+CLKE DECL YLF W++ RRGLVHL
Sbjct: 121 VLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
Query: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
CCSK+ NY P R L+ IY +SIQ+LE+ K YL +M NLR+L +
Sbjct: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLA 240
Query: 241 RCHHSMSDNELEGRLVTKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL 300
+ ++ + S FL L + Q+L IK I+ HLE L+R L+NPL
Sbjct: 241 FGYERELYVSVQWPCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAFIF 300
Query: 301 TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEGCQ 360
+ YL + DM+CLSQYPSL LK L L ++L++ LEPLG LLEK+AA+L+TL+L+ C+
Sbjct: 301 SDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDCR 360
Query: 361 IHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLRHTSGLSKLSLETYPAPEESLN 420
I QL +LP LSHCSQLTTF F N SM ALKDLLRHT GLSKL LE YPAP ESL+
Sbjct: 361 IQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTGGLSKLGLELYPAPLESLD 420
Query: 421 SLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLC 473
V+WEI +RAELM TLREVRQPKRIF GP PCP+CGS PSE+++ HLC
Sbjct: 421 YKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPNCGSWPSEKVDFHLC 473
>gi|194306638 PRAME family member 3 [Homo sapiens]
Length = 481
Score = 546 bits (1406), Expect = e-155
Identities = 290/474 (61%), Positives = 345/474 (72%), Gaps = 2/474 (0%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
MS+QAP RLLELAGQSLL DQAL+IS ++ELPR L+ PLF+EAF R + L VMVQAWP
Sbjct: 3 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F CLPLGSLMKT LE L +++G+ LL QK RPRR KLQVL+LRDVDENFW W GA
Sbjct: 63 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSGAR 122
Query: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
LSC PE MSKRQT EDCPR GE QPLKVF+D+CLKE DE L + WV RRG VHL
Sbjct: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
Query: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
CC+K+VNY I + R L+ +Y +SIQ LEI NM WP +I + YL +M+NLRKL S
Sbjct: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFIRYLSQMRNLRKLFIS 242
Query: 241 -RCHHSMSDNELEGRLVTKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLE 299
C + +S + E +LV +FSSV LRLE+LQ+L ++ + FF GHL+QLIRCL++PLE L
Sbjct: 243 DGCRYLLSSDSQE-QLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETLA 301
Query: 300 LTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEGC 359
LTYG+L + D+KCL +YPSL LK LNLS+ L I LEPL ALLEK+AA+L+TL L C
Sbjct: 302 LTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVDC 361
Query: 360 QIHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLRHTSGLSKLSLETYPAPEESL 419
I S+L ILP LS CS LTTF F N SM LKDLLRHT LS LSLETYPAP ESL
Sbjct: 362 GIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESL 421
Query: 420 NSLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLC 473
+ RV E+ L+AELM LREVR+PKRIF GP CP CG+SP+E+LE + C
Sbjct: 422 DDRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFC 475
>gi|157426839 PRAME family member 17 [Homo sapiens]
Length = 474
Score = 544 bits (1402), Expect = e-155
Identities = 285/477 (59%), Positives = 342/477 (71%), Gaps = 8/477 (1%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
MS+Q+P RLLELAGQSLLR+Q L+I ++ELPR ++ +FMEA RHF+ L +MVQAWP
Sbjct: 1 MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F LPLGSLMKT HLETL+A+L+GL LL QK RPRRWKLQVLDLRDVD NFW W GA
Sbjct: 61 FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
Query: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
ALSC PE MSKRQT ED PR GEHQPLKVFID+C KE DECL YL +W++ RRGLVHL
Sbjct: 121 ALSCSPEAMSKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
Query: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
CC+K+ NY P R LK +Y +SIQ+LEI+ K YL +M NLRKL +
Sbjct: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
Query: 241 RCHHSMSDNEL----EGRLVTKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLE 296
+ D+EL + + V FL L + Q+L I+ I+ HLE L+RCL+NPL
Sbjct: 241 FGY----DDELYVSGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLG 296
Query: 297 NLELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLIL 356
+ YL ++DM+CLSQYPSL LK L+L ++L++ +LEPLGALLEK+AA+LE L L
Sbjct: 297 TFIFCHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTL 356
Query: 357 EGCQIHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLRHTSGLSKLSLETYPAPE 416
+ CQI SQL +LP LS CSQLTTFYF N S ALKDLL HT GLSKL LE YPAP
Sbjct: 357 KDCQIQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPL 416
Query: 417 ESLNSLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLC 473
E L++ V+WEI A +RAELMCTLREVRQPKRIF GP PCPSCGS PSE+++ HLC
Sbjct: 417 ECLDNRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGSWPSEKVDFHLC 473
>gi|113865933 PRAME family member 16 [Homo sapiens]
Length = 474
Score = 542 bits (1397), Expect = e-154
Identities = 284/477 (59%), Positives = 341/477 (71%), Gaps = 8/477 (1%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
MS+Q+P RLLELAGQSLLR+Q L+I ++ELPR ++ +FMEA RHF+ L +MVQAWP
Sbjct: 1 MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F LPLGSLMKT HLETL+A+L+GL LL QK RPRRWKLQVLDLRDVD NFW W GA
Sbjct: 61 FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
Query: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
ALSC PE M KRQT ED PR GEHQPLKVFID+C KE DECL YL +W++ RRGLVHL
Sbjct: 121 ALSCSPEAMRKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
Query: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
CC+K+ NY P R LK +Y +SIQ+LEI+ K YL +M NLRKL +
Sbjct: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
Query: 241 RCHHSMSDNEL----EGRLVTKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLE 296
+ D+EL + + V FL L + Q+L I+ I+ HLE L+RCL+NPL
Sbjct: 241 FGY----DDELYVSGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLG 296
Query: 297 NLELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLIL 356
+ YL ++DM+CLSQYPSL LK L+L ++L++ +LEPLGALLEK+AA+LE L L
Sbjct: 297 TFIFCHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTL 356
Query: 357 EGCQIHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLRHTSGLSKLSLETYPAPE 416
+ CQI SQL +LP LS CSQLTTFYF N S ALKDLL HT GLSKL LE YPAP
Sbjct: 357 KDCQIQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPL 416
Query: 417 ESLNSLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLC 473
E L++ V+WEI A +RAELMCTLREVRQPKRIF GP PCPSCGS PSE+++ HLC
Sbjct: 417 ECLDNRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGSWPSEKVDFHLC 473
>gi|239741051 PREDICTED: similar to PRAME family member 10 [Homo
sapiens]
Length = 426
Score = 507 bits (1305), Expect = e-143
Identities = 269/473 (56%), Positives = 315/473 (66%), Gaps = 48/473 (10%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
MS+QAP RLLELAGQSLLR+Q L+I ++ELPR ++ +FMEAF R F+ L +MVQAWP
Sbjct: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F LPLGSLMKT HLETL+A+L GL L+ QK RPRRWKLQVLDLRDVDENFW W GA
Sbjct: 61 FLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
Query: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
LSC PE MSKRQT EDCPRMGE QPLKVFID+CLKE DECL YLF W++ RRGLVHL
Sbjct: 121 VLSCSPEAMSKRQTVEDCPRMGERQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
Query: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
CCSK+ NY P R L+ IY +SIQ+LE+ K YL +M NLR+L F
Sbjct: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFFP 240
Query: 241 RCHHSMSDNELEGRLVTKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL 300
R L+NPL
Sbjct: 241 RY------------------------------------------------LKNPLGAFIF 252
Query: 301 TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEGCQ 360
+ YL + DM+CLSQYPSL LK L L ++L++ +LEPLG LLEK+AA+L+TL+L+ C+
Sbjct: 253 SDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTNLEPLGVLLEKVAATLKTLVLKDCR 312
Query: 361 IHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLRHTSGLSKLSLETYPAPEESLN 420
I QL +LP LSHCSQLTTF F N SM ALKDLLRHT GLSKL LE YPAP ESL+
Sbjct: 313 IQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESLD 372
Query: 421 SLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLC 473
V+WEI +RAELM TLREVRQPKRIF GP PCP+CGS PSE+++ HLC
Sbjct: 373 YKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGSWPSEKVDFHLC 425
>gi|239741055 PREDICTED: similar to PRAME family member 10 [Homo
sapiens]
Length = 426
Score = 506 bits (1303), Expect = e-143
Identities = 269/473 (56%), Positives = 314/473 (66%), Gaps = 48/473 (10%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
MS+QAP RLLELAGQSLLR+Q L+I ++ELPR ++ +FMEAF R F+ L +MVQAWP
Sbjct: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F LPLGSLMKT HLETL+A+L GL L+ QK RPRRWKLQVLDLRDVDENFW W GA
Sbjct: 61 FLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
Query: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
LSC PE MSKRQT EDCPRMGE QPLKVFID+CLKE DECL YLF W++ RRGLVHL
Sbjct: 121 VLSCSPEAMSKRQTVEDCPRMGERQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
Query: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
CCSK+ NY P R L+ IY +SIQ+LE+ K YL +M NLR+L F
Sbjct: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFFP 240
Query: 241 RCHHSMSDNELEGRLVTKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL 300
R L+NPL
Sbjct: 241 RY------------------------------------------------LKNPLGAFIF 252
Query: 301 TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEGCQ 360
+ YL + DM+CLSQYPSL LK L L ++L++ LEPLG LLEK+AA+L+TL+L+ C+
Sbjct: 253 SDAYLADRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDCR 312
Query: 361 IHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLRHTSGLSKLSLETYPAPEESLN 420
I QL +LP LSHCSQLTTF F N SM ALKDLLRHT GLSKL LE YPAP ESL+
Sbjct: 313 IQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESLD 372
Query: 421 SLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLC 473
V+WEI +RAELM TLREVRQPKRIF GP PCP+CGS PSE+++ HLC
Sbjct: 373 YKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGSWPSEKVDFHLC 425
>gi|239741047 PREDICTED: PRAME family member 25-like [Homo sapiens]
Length = 474
Score = 469 bits (1207), Expect = e-132
Identities = 258/476 (54%), Positives = 319/476 (67%), Gaps = 4/476 (0%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
MS+QAP RLLELAGQSLL DQAL+IS ++ELPR L+ PLF+EAF R + L VMVQAWP
Sbjct: 1 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 60
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F CLPLGSLMKT LE L +++G+ LL QK RPRR KLQVL+LRDVDENFW W GA
Sbjct: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSGAR 120
Query: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
LSC PE MSKRQT EDCPR GE QPLKVF+D+CLKE DE L + WV RRG VHL
Sbjct: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 180
Query: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
CC+K+VNY I + R L+ +Y +SIQ LEI NM WP +I + YL +M+NLRKL S
Sbjct: 181 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSPYLSQMRNLRKLFIS 240
Query: 241 -RCHHSMSDNELEGRLVTKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLE 299
C + +S + E + F++ FL+L LQ L + ++F GHL+QL+ CL+ L+ L
Sbjct: 241 DGCRYLLSSDSQE--QIAPFTTQFLKLHCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLT 298
Query: 300 LTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEGC 359
+T LLE D+K LSQ PS+ LK L+LS + L SL PL LLEK+AA+LE L L+ C
Sbjct: 299 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 358
Query: 360 QIHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLRHTSGLSKLSLETYPAPEESL 419
I SQ++AILP LS C +L TF F N +SM L++LL HT L L LE YPAP ES
Sbjct: 359 GIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCLELYPAPRESY 418
Query: 420 NSLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELEL-HLCC 474
+ + W F +RAELM +R++R PKRI G CP CG+ +LE CC
Sbjct: 419 GADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGTDYCPDCGNRSFYDLEADQYCC 474
>gi|124249372 PRAME family member 12 [Homo sapiens]
Length = 483
Score = 464 bits (1195), Expect = e-131
Identities = 257/480 (53%), Positives = 326/480 (67%), Gaps = 8/480 (1%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
MS+QAPPRLLELA QSLLRD+AL+I +EELPR L+ PLFMEAF RR +TLT MVQAWP
Sbjct: 1 MSLQAPPRLLELAEQSLLRDRALAIPTLEELPRELFPPLFMEAFTRRCCETLTTMVQAWP 60
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
FTCLPLGSLMK+ +LE +A+LEGL LL QK RPRRWKLQVLDLR+VDENFW W GA
Sbjct: 61 FTCLPLGSLMKSCNLEIFRAVLEGLDALLAQKVRPRRWKLQVLDLRNVDENFWGIWSGAS 120
Query: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
ALS PE +SKR+TA +CPR G QPL V +D+C K DECL + +W QR+GL+H+
Sbjct: 121 ALS--PEALSKRRTAGNCPRPGGQQPLMVILDLCFKNGMLDECLTHFLEWGKQRKGLLHV 178
Query: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
CC +L + I + + L + L+ IQ++E+ ++ + YL +M+NLRKLV
Sbjct: 179 CCKELQIFGIAIHRIIEVLNTVELDCIQEVEVCCPWELSILIRFAPYLGQMRNLRKLVLF 238
Query: 241 RCHHSMS-DNELEGRLVTKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLE 299
H S + + + V +F+S FL+L++ Q L + ++F GHL+QL+RCLQ PLE +
Sbjct: 239 NIHVSACIPLDRKEQFVIQFTSQFLKLDYFQKLYMHSVSFLEGHLDQLLRCLQAPLETVV 298
Query: 300 LTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEGC 359
+T L E D+K LS PS+ LK L+L + L S EPL LLE+ A+L+TL LE C
Sbjct: 299 MTECLLSESDLKHLSWCPSIRQLKELDLRGITLTHFSPEPLSVLLEQAEATLQTLDLEDC 358
Query: 360 QIHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLRHTSGLSKLSLETYPAPEESL 419
I SQLSAILP LS CSQL+TF F N +SM AL++LLRHT GLSKLSLE YPAP ES
Sbjct: 359 GIVDSQLSAILPALSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESY 418
Query: 420 NSLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELE-----LHLCC 474
++ + W F+ L AELM TLR++RQPK I PCP CG S +LE L+ CC
Sbjct: 419 DAQGALCWGRFSQLGAELMKTLRDLRQPKIIVFSTVPCPRCGIRASYDLEPSHCLLNACC 478
>gi|239741053 PREDICTED: similar to Putative PRAME family member 24
[Homo sapiens]
Length = 474
Score = 448 bits (1153), Expect = e-126
Identities = 255/476 (53%), Positives = 325/476 (68%), Gaps = 7/476 (1%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
MSI+APPRLLELA Q LLRDQAL+IS MEELPR L+ LFMEAF RR +TL MVQAWP
Sbjct: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
FT LPLGSLMK+ HLE+LK++LEG+ +LLTQ+ RPR+ KLQVLDLR+VDENF + GA
Sbjct: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
Query: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
A FPE +S++QTA++CP G QP VFID+CLK DECL +L +W QR+GL+H+
Sbjct: 121 A--SFPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178
Query: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
CC +L + PI + + L ++ L+ IQ++E+ + K YL +M+NLRKLV
Sbjct: 179 CCKELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMRNLRKLVLF 238
Query: 241 RCHHSMS---DNELEGRLVTKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLEN 297
S DN+ G+ + +F+S FL+L++ Q L + ++F GHL+QL+RCLQ LE
Sbjct: 239 NIRASACIPPDNK--GQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLEM 296
Query: 298 LELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILE 357
+ +T L E D+K LS PS+ LK L+L V L S EPL LLE++ A+L+TL LE
Sbjct: 297 VVMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDLE 356
Query: 358 GCQIHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLRHTSGLSKLSLETYPAPEE 417
C I SQLSAILP LS CSQL+TF F N +SM AL++LLRHT GLSKLSLE YPAP E
Sbjct: 357 DCGIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLE 416
Query: 418 SLNSLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLC 473
S ++ + W FA L AELM TLR++RQPK I PCP CG S +LE C
Sbjct: 417 SYDTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHC 472
>gi|59676587 PRAME family member 8 [Homo sapiens]
Length = 474
Score = 448 bits (1153), Expect = e-126
Identities = 255/476 (53%), Positives = 325/476 (68%), Gaps = 7/476 (1%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
MSI+APPRLLELA Q LLRDQAL+IS MEELPR L+ LFMEAF RR +TL MVQAWP
Sbjct: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
FT LPLGSLMK+ HLE+LK++LEG+ +LLTQ+ RPR+ KLQVLDLR+VDENF + GA
Sbjct: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
Query: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
A FPE +S++QTA++CP G QP VFID+CLK DECL +L +W QR+GL+H+
Sbjct: 121 A--SFPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178
Query: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
CC +L + PI + + L ++ L+ IQ++E+ + K YL +M+NLRKLV
Sbjct: 179 CCQELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMRNLRKLVLF 238
Query: 241 RCHHSMS---DNELEGRLVTKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLEN 297
S DN+ G+ + +F+S FL+L++ Q L + ++F GHL+QL+RCLQ LE
Sbjct: 239 NIRASACIPPDNK--GQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLEM 296
Query: 298 LELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILE 357
+ +T L E D+K LS PS+ LK L+L V L S EPL LLE++ A+L+TL LE
Sbjct: 297 VVMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDLE 356
Query: 358 GCQIHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLRHTSGLSKLSLETYPAPEE 417
C I SQLSAILP LS CSQL+TF F N +SM AL++LLRHT GLSKLSLE YPAP E
Sbjct: 357 DCGIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLE 416
Query: 418 SLNSLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLC 473
S ++ + W FA L AELM TLR++RQPK I PCP CG S +LE C
Sbjct: 417 SYDTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHC 472
>gi|59676593 PRAME family member 7 [Homo sapiens]
Length = 474
Score = 446 bits (1146), Expect = e-125
Identities = 254/476 (53%), Positives = 324/476 (68%), Gaps = 7/476 (1%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
MSI+APPRLLELA Q LLRDQAL+IS MEELPR L+ LFMEAF RR +TL MVQAWP
Sbjct: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
FT LPLGSLMK+ HLE+LK++LEG+ +LLTQ+ RPR+ KLQVLDLR+VDENF + GA
Sbjct: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
Query: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
A FPE +S++QTA++CP G QP VFID+CLK DECL +L +W QR+GL+H+
Sbjct: 121 A--SFPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178
Query: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
CC +L + PI + + L ++ L+ IQ++E+ + K YL +M+NLRKLV
Sbjct: 179 CCKELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMRNLRKLVLF 238
Query: 241 RCHHSMS---DNELEGRLVTKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLEN 297
S DN+ G+ + +F+S FL+L++ Q L + ++F GHL+QL+RCLQ LE
Sbjct: 239 NIRASACIPPDNK--GQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLEM 296
Query: 298 LELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILE 357
+ +T L E D+K LS PS+ LK L+L V L S EPL LLE++ A+L+TL LE
Sbjct: 297 VVMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDLE 356
Query: 358 GCQIHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLRHTSGLSKLSLETYPAPEE 417
C I SQLSAILP LS CSQL+TF F N +SM AL++LLRHT GLSKLSLE YPAP E
Sbjct: 357 DCGIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLE 416
Query: 418 SLNSLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLC 473
S ++ + W FA L AELM T R++RQPK I PCP CG S +LE C
Sbjct: 417 SYDTQGALCWGRFAELGAELMKTPRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHC 472
>gi|153792112 PRAME family member 20 [Homo sapiens]
Length = 475
Score = 429 bits (1103), Expect = e-120
Identities = 241/475 (50%), Positives = 305/475 (64%), Gaps = 2/475 (0%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
MSI+ PPRLLELAG+SLLRD+AL+IS +EELP L+ PLFMEAF RRH + L +MVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWP 60
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F LPLGSLMK ET +A+L+GL LLT + R RRWKLQVLDL+DV ENFW W A
Sbjct: 61 FLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAM 120
Query: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
A C P M R+ +DCPRM QPL VFID+CLK DE LF WV QR GLVHL
Sbjct: 121 ARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHL 180
Query: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWP-RLIRKLRCYLKEMKNLRKLVF 239
CC KL ++R LK + L+ IQ++E+ N +W ++ + YL +M+NLRKLV
Sbjct: 181 CCKKLKMLGMLFHNIRNILKTVNLDCIQEVEV-NCNWTLPVLAEFTPYLGQMRNLRKLVL 239
Query: 240 SRCHHSMSDNELEGRLVTKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLE 299
S E + VT+F++ FL+L LQ L + ++F GHL+Q++ CL+ L L
Sbjct: 240 SDIDSRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNILA 299
Query: 300 LTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEGC 359
+T LLE D+K LS+YPS+G LK L+LS L SL PL LLEK+AA+LE L L+ C
Sbjct: 300 ITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDDC 359
Query: 360 QIHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLRHTSGLSKLSLETYPAPEESL 419
I SQ++AILP LS C +LTTF F N +S L++LL HT L+ L LE YPAP ES
Sbjct: 360 GIVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRESY 419
Query: 420 NSLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLCC 474
+ V FA L AELM +R +R+P+RI CP CG+ +LE+ CC
Sbjct: 420 DVRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGNRSLYDLEVDRCC 474
>gi|153945800 PRAME family member 21 [Homo sapiens]
Length = 475
Score = 429 bits (1103), Expect = e-120
Identities = 241/475 (50%), Positives = 305/475 (64%), Gaps = 2/475 (0%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
MSI+ PPRLLELAG+SLLRD+AL+IS +EELP L+ PLFMEAF RRH + L +MVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWP 60
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F LPLGSLMK ET +A+L+GL LLT + R RRWKLQVLDL+DV ENFW W A
Sbjct: 61 FLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAM 120
Query: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
A C P M R+ +DCPRM QPL VFID+CLK DE LF WV QR GLVHL
Sbjct: 121 ARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHL 180
Query: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWP-RLIRKLRCYLKEMKNLRKLVF 239
CC KL ++R LK + L+ IQ++E+ N +W ++ + YL +M+NLRKLV
Sbjct: 181 CCKKLKMLGMLFHNIRNILKTVNLDCIQEVEV-NCNWTLPVLAEFTPYLGQMRNLRKLVL 239
Query: 240 SRCHHSMSDNELEGRLVTKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLE 299
S E + VT+F++ FL+L LQ L + ++F GHL+Q++ CL+ L L
Sbjct: 240 SDIDSRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNILA 299
Query: 300 LTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEGC 359
+T LLE D+K LS+YPS+G LK L+LS L SL PL LLEK+AA+LE L L+ C
Sbjct: 300 ITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDDC 359
Query: 360 QIHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLRHTSGLSKLSLETYPAPEESL 419
I SQ++AILP LS C +LTTF F N +S L++LL HT L+ L LE YPAP ES
Sbjct: 360 GIVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRESY 419
Query: 420 NSLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLCC 474
+ V FA L AELM +R +R+P+RI CP CG+ +LE+ CC
Sbjct: 420 DVRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGNRSLYDLEVDRCC 474
>gi|148356236 PRAME family member 15 [Homo sapiens]
Length = 478
Score = 410 bits (1055), Expect = e-114
Identities = 233/477 (48%), Positives = 304/477 (63%), Gaps = 4/477 (0%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
MSI+ PPRLLELAG+SLLRDQAL++S +EELP L+ PLFMEAF RR + L +MVQAWP
Sbjct: 3 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 62
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F LPL L+K LE +A+L+GL LLTQ RPRRWKLQVLDL+DV ENFW W A
Sbjct: 63 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
Query: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
A CF ++ +DCPRM QPL VF+++ LK DE L YL WV QR+ L+HL
Sbjct: 123 AHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLLHL 182
Query: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWP-RLIRKLRCYLKEMKNLRKLVF 239
CC KL P +++R LK++ L+ IQ++E+ N W ++ + YL M+NL+KLV
Sbjct: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKLVL 241
Query: 240 SRCHHS-MSDNELEGRLVTKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENL 298
S S E + +VT+F++ FL+L LQ L + ++F GHL+QL+ CL+ L+ L
Sbjct: 242 SHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVL 301
Query: 299 ELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEG 358
+T LLE D+K LSQ PS+ LK L+LS + L SL PL LLEK+AA+LE L L+
Sbjct: 302 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 361
Query: 359 CQIHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLRHTSGLSKLSLETYPAPEES 418
C I SQ++AILP LS C +L TF F N + M L++LL HT L L +E YPAP ES
Sbjct: 362 CGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRES 421
Query: 419 LNSLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELEL-HLCC 474
+ + W FA +RAELM +R++R PKRI CP CG+ +LE CC
Sbjct: 422 YGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC 478
>gi|61102721 PRAME family member 9 [Homo sapiens]
Length = 478
Score = 410 bits (1055), Expect = e-114
Identities = 233/477 (48%), Positives = 304/477 (63%), Gaps = 4/477 (0%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
MSI+ PPRLLELAG+SLLRDQAL++S +EELP L+ PLFMEAF RR + L +MVQAWP
Sbjct: 3 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 62
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F LPL L+K LE +A+L+GL LLTQ RPRRWKLQVLDL+DV ENFW W A
Sbjct: 63 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
Query: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
A CF ++ +DCPRM QPL VF+++ LK DE L YL WV QR+ L+HL
Sbjct: 123 AHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLLHL 182
Query: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWP-RLIRKLRCYLKEMKNLRKLVF 239
CC KL P +++R LK++ L+ IQ++E+ N W ++ + YL M+NL+KLV
Sbjct: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKLVL 241
Query: 240 SRCHHS-MSDNELEGRLVTKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENL 298
S S E + +VT+F++ FL+L LQ L + ++F GHL+QL+ CL+ L+ L
Sbjct: 242 SHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVL 301
Query: 299 ELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEG 358
+T LLE D+K LSQ PS+ LK L+LS + L SL PL LLEK+AA+LE L L+
Sbjct: 302 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 361
Query: 359 CQIHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLRHTSGLSKLSLETYPAPEES 418
C I SQ++AILP LS C +L TF F N + M L++LL HT L L +E YPAP ES
Sbjct: 362 CGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRES 421
Query: 419 LNSLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELEL-HLCC 474
+ + W FA +RAELM +R++R PKRI CP CG+ +LE CC
Sbjct: 422 YGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC 478
>gi|61696142 PRAME family member 5 [Homo sapiens]
Length = 476
Score = 410 bits (1055), Expect = e-114
Identities = 232/476 (48%), Positives = 304/476 (63%), Gaps = 3/476 (0%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
MSI+ PPRLLELAG+SLLRDQAL++S +EELP L+ PLFMEAF RR + L +MVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F LPL L+K LE +A+L+GL LLTQ PRRWKLQVLDL+DV ENFW W A
Sbjct: 61 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
Query: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
A CF ++ +DCPRM QPL VF+++ LK DE L L WV QR+ L+HL
Sbjct: 121 AHGCFLNAKRNKKPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
Query: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWP-RLIRKLRCYLKEMKNLRKLVF 239
CC KL P +++R LK++ L+ IQ++E+ N W ++ + YL M+NL+KLV
Sbjct: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKLVL 239
Query: 240 SRCHHS-MSDNELEGRLVTKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENL 298
S S E + +VT+F++ FL+L LQ L + ++F GHL+QL+ CL+ L+ L
Sbjct: 240 SHMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVL 299
Query: 299 ELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEG 358
+T LLE D+K LSQ PS+ LK L+LS + L SL PL LLEK+AA+LE L L+
Sbjct: 300 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 359
Query: 359 CQIHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLRHTSGLSKLSLETYPAPEES 418
C I SQ++AILP LS C +L TF F N +SM L++LL HT L L +E YPAP ES
Sbjct: 360 CGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRES 419
Query: 419 LNSLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLCC 474
++ + W FA +RAELM +R++R PKRI CP CG+ +LE CC
Sbjct: 420 YDADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQCC 475
>gi|58219004 PRAME family member 6 [Homo sapiens]
Length = 476
Score = 410 bits (1054), Expect = e-114
Identities = 232/476 (48%), Positives = 303/476 (63%), Gaps = 3/476 (0%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
MSI+ PPRLLELAG+SLLRDQAL++S +EELP L+ PLFMEAF RR + L +MVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F LPL L+K LE +A+L+GL LLTQ PRRWKLQVLDL+DV ENFW W A
Sbjct: 61 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
Query: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
A CF + +DCPRM QPL VF+++ LK DE L L WV QR+ L+HL
Sbjct: 121 ARGCFLNAKRNKTPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
Query: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWP-RLIRKLRCYLKEMKNLRKLVF 239
CC KL P +++R LK++ L+ IQ++E+ N W ++ + YL M+NL+KLV
Sbjct: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKLVL 239
Query: 240 SRCHHS-MSDNELEGRLVTKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENL 298
S S E + +VT+F++ FL+L LQ L + ++F GHL+QL+ CL+ L+ L
Sbjct: 240 SHMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVL 299
Query: 299 ELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEG 358
+T LLE D+K LSQ PS+ LK L+LS + L SL PL LLEK+AA+LE L L+
Sbjct: 300 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 359
Query: 359 CQIHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLRHTSGLSKLSLETYPAPEES 418
C I SQ++AILP LS C +L TF F N +SM L++LL HT L L +E YPAP ES
Sbjct: 360 CGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRES 419
Query: 419 LNSLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLCC 474
++ + W FA +RAELM +R++R PKRI CP CG+ +LE CC
Sbjct: 420 YDADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQCC 475
>gi|239741045 PREDICTED: PRAME family member 23 [Homo sapiens]
Length = 476
Score = 407 bits (1047), Expect = e-114
Identities = 231/476 (48%), Positives = 303/476 (63%), Gaps = 3/476 (0%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
MSI+ PPRLLELAG+SLLRDQAL++S +EELP L+ PLFMEAF RR + L +MVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F LPL L+K LE +A+L+GL LLTQ PRRWKLQVLDL+DV ENFW W A
Sbjct: 61 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
Query: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
A CF ++ +DCPRM QPL VF+++ LK DE L L WV QR+ L+HL
Sbjct: 121 AHGCFLNAKRNKKPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
Query: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWP-RLIRKLRCYLKEMKNLRKLVF 239
CC KL P +++R LK++ L+ IQ++E+ N W ++ + YL M+NL+KLV
Sbjct: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKLVL 239
Query: 240 SRCHHS-MSDNELEGRLVTKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENL 298
S S E + +VT+F++ FL+L LQ L + ++F GHL+QL+ CL+ L+ L
Sbjct: 240 SHMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVL 299
Query: 299 ELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEG 358
+T LLE D+K LSQ PS+ LK L+LS + L SL PL LLEK+AA+LE L L+
Sbjct: 300 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 359
Query: 359 CQIHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLRHTSGLSKLSLETYPAPEES 418
C I SQ++AILP LS C +L TF F N +SM L++LL HT L L +E YPAP ES
Sbjct: 360 CGIIDSQVNAILPALSCCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRES 419
Query: 419 LNSLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLCC 474
++ + W F +RAELM +R++R PKRI CP CG+ +LE CC
Sbjct: 420 YDADGTLCWSRFPQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQCC 475
>gi|239741043 PREDICTED: PRAME family member 11 [Homo sapiens]
Length = 513
Score = 404 bits (1037), Expect = e-112
Identities = 232/477 (48%), Positives = 300/477 (62%), Gaps = 4/477 (0%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
MSI+ PPRLLEL G+SLLRDQAL++S +EELP L+ PLFMEAF RR + L +MVQAWP
Sbjct: 38 MSIRIPPRLLELXGRSLLRDQALAVSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 97
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F LPL L+K LE +A+L+GL LLTQ RPRRWKLQVLDL+DV ENFW W A
Sbjct: 98 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 157
Query: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
A CF + +DCPRM E QPL VF+++ LK DE L L WV QRR L+HL
Sbjct: 158 AHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTLDEYLTCLLLWVKQRRDLLHL 217
Query: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSW-PRLIRKLRCYLKEMKNLRKLVF 239
CC KL P +++R LK++ L+ IQ++E+ N W ++ + YL ++NL+KLV
Sbjct: 218 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWILPILTQFTPYLGHLRNLQKLVL 276
Query: 240 SRCHHS-MSDNELEGRLVTKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENL 298
S S E + +VT+F++ FL+L LQ L + ++F GHL+QL+ CL+ L+ L
Sbjct: 277 SHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVL 336
Query: 299 ELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEG 358
+T LLE D+K LSQ PS+ LK L+LS + L SL PL LLEK+AA+LE L L+
Sbjct: 337 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 396
Query: 359 CQIHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLRHTSGLSKLSLETYPAPEES 418
C I SQ++AILP LS C +L TF F N + M L++LL HT L L LE YPAP+ES
Sbjct: 397 CGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCLELYPAPQES 456
Query: 419 LNSLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELEL-HLCC 474
+ + W FA +RAELM +R +R PKRI CP G +LE CC
Sbjct: 457 YGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPDHGDRSFYDLEADQYCC 513
>gi|59958373 PRAME family member 4 [Homo sapiens]
Length = 478
Score = 401 bits (1030), Expect = e-112
Identities = 229/477 (48%), Positives = 300/477 (62%), Gaps = 4/477 (0%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
MSI PPRLLELAG+SLLRDQAL++S +EELP L+ PLFMEAF RR + L +MVQ+WP
Sbjct: 3 MSIWTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQSWP 62
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F LPL L+K LE +A+L+GL LL RPRRWKLQVLDL+DV ENFW W A
Sbjct: 63 FRRLPLRPLIKMPCLEAFQAVLDGLDALLNLGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
Query: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
A CF ++ EDCPRM QPL VF+++ LK DE L L WV QR+ L+HL
Sbjct: 123 AHGCFLNAKRNKKPVEDCPRMRGRQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 182
Query: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWP-RLIRKLRCYLKEMKNLRKLVF 239
CC KL P +++R LK++ L+ IQ++E+ N W ++ + YL M+NL+KL+
Sbjct: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKLIL 241
Query: 240 SRCHHS-MSDNELEGRLVTKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENL 298
S S E + +VT+F++ FL+L LQ L + ++F GHL+QL+ CL+ L+ L
Sbjct: 242 SHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKFL 301
Query: 299 ELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEG 358
+T LLE D+K LSQ PS+ LK L+LS + L SL PL LLEK+AA+LE L L+
Sbjct: 302 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 361
Query: 359 CQIHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLRHTSGLSKLSLETYPAPEES 418
C I SQ++AILP LS C +L TF F N + M L++LL HT L L +E YPAP ES
Sbjct: 362 CGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRES 421
Query: 419 LNSLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELEL-HLCC 474
+ + W FA +RAELM +R++R PKRI CP CG+ +LE CC
Sbjct: 422 YGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC 478
>gi|46249373 preferentially expressed antigen in melanoma [Homo
sapiens]
Length = 509
Score = 358 bits (919), Expect = 6e-99
Identities = 217/482 (45%), Positives = 296/482 (61%), Gaps = 13/482 (2%)
Query: 5 APPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWPFTCL 64
+P RL+ELAGQSLL+D+AL+I+A+E LPR L+ PLFM AF RH QTL MVQAWPFTCL
Sbjct: 22 SPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCL 81
Query: 65 PLGSLMKT--LHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLR-DVDENFWARWPGAWA 121
PLG LMK LHLET KA+L+GL +LL Q+ RPRRWKLQVLDLR + ++FW W G A
Sbjct: 82 PLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVWSGNRA 141
Query: 122 -LSCFPET-----MSKRQTAEDCPRMGEHQ--PLKVFIDICLKEIPQDECLRYLFQWVYQ 173
L FPE M+K++ + E P++V +D+ LKE DE YL + V +
Sbjct: 142 SLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLIEKVKR 201
Query: 174 RRGLVHLCCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKN 233
++ ++ LCC KL + P++ ++ LK++ L+SI+ LE+ + K YL +M N
Sbjct: 202 KKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYLGQMIN 261
Query: 234 LRKLVFSRCH-HSMSDNELEGRLVTKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQ 292
LR+L+ S H S E E + + +F+S FL L+ LQ L + + F G L+QL+R +
Sbjct: 262 LRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQLLRHVM 321
Query: 293 NPLENLELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLE 352
NPLE L +T L E D+ LSQ PS+ L L+LS V+L +S EPL ALLE+ +A+L+
Sbjct: 322 NPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERASATLQ 381
Query: 353 TLILEGCQIHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLRHTSGLSKLSLETY 412
L+ + C I QL A+LP LSHCSQLTT F N +S+ AL+ LL+H GLS L+ Y
Sbjct: 382 DLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNLTHVLY 441
Query: 413 PAPEESLNSL-VRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELH 471
P P ES + + E A L A L L E+ +P +++ PCP CG + E
Sbjct: 442 PVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGDRTFYDPEPI 501
Query: 472 LC 473
LC
Sbjct: 502 LC 503
>gi|46249371 preferentially expressed antigen in melanoma [Homo
sapiens]
Length = 509
Score = 358 bits (919), Expect = 6e-99
Identities = 217/482 (45%), Positives = 296/482 (61%), Gaps = 13/482 (2%)
Query: 5 APPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWPFTCL 64
+P RL+ELAGQSLL+D+AL+I+A+E LPR L+ PLFM AF RH QTL MVQAWPFTCL
Sbjct: 22 SPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCL 81
Query: 65 PLGSLMKT--LHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLR-DVDENFWARWPGAWA 121
PLG LMK LHLET KA+L+GL +LL Q+ RPRRWKLQVLDLR + ++FW W G A
Sbjct: 82 PLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVWSGNRA 141
Query: 122 -LSCFPET-----MSKRQTAEDCPRMGEHQ--PLKVFIDICLKEIPQDECLRYLFQWVYQ 173
L FPE M+K++ + E P++V +D+ LKE DE YL + V +
Sbjct: 142 SLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLIEKVKR 201
Query: 174 RRGLVHLCCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKN 233
++ ++ LCC KL + P++ ++ LK++ L+SI+ LE+ + K YL +M N
Sbjct: 202 KKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYLGQMIN 261
Query: 234 LRKLVFSRCH-HSMSDNELEGRLVTKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQ 292
LR+L+ S H S E E + + +F+S FL L+ LQ L + + F G L+QL+R +
Sbjct: 262 LRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQLLRHVM 321
Query: 293 NPLENLELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLE 352
NPLE L +T L E D+ LSQ PS+ L L+LS V+L +S EPL ALLE+ +A+L+
Sbjct: 322 NPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERASATLQ 381
Query: 353 TLILEGCQIHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLRHTSGLSKLSLETY 412
L+ + C I QL A+LP LSHCSQLTT F N +S+ AL+ LL+H GLS L+ Y
Sbjct: 382 DLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNLTHVLY 441
Query: 413 PAPEESLNSL-VRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELH 471
P P ES + + E A L A L L E+ +P +++ PCP CG + E
Sbjct: 442 PVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGDRTFYDPEPI 501
Query: 472 LC 473
LC
Sbjct: 502 LC 503
>gi|46249369 preferentially expressed antigen in melanoma [Homo
sapiens]
Length = 509
Score = 358 bits (919), Expect = 6e-99
Identities = 217/482 (45%), Positives = 296/482 (61%), Gaps = 13/482 (2%)
Query: 5 APPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWPFTCL 64
+P RL+ELAGQSLL+D+AL+I+A+E LPR L+ PLFM AF RH QTL MVQAWPFTCL
Sbjct: 22 SPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCL 81
Query: 65 PLGSLMKT--LHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLR-DVDENFWARWPGAWA 121
PLG LMK LHLET KA+L+GL +LL Q+ RPRRWKLQVLDLR + ++FW W G A
Sbjct: 82 PLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVWSGNRA 141
Query: 122 -LSCFPET-----MSKRQTAEDCPRMGEHQ--PLKVFIDICLKEIPQDECLRYLFQWVYQ 173
L FPE M+K++ + E P++V +D+ LKE DE YL + V +
Sbjct: 142 SLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLIEKVKR 201
Query: 174 RRGLVHLCCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKN 233
++ ++ LCC KL + P++ ++ LK++ L+SI+ LE+ + K YL +M N
Sbjct: 202 KKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYLGQMIN 261
Query: 234 LRKLVFSRCH-HSMSDNELEGRLVTKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQ 292
LR+L+ S H S E E + + +F+S FL L+ LQ L + + F G L+QL+R +
Sbjct: 262 LRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQLLRHVM 321
Query: 293 NPLENLELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLE 352
NPLE L +T L E D+ LSQ PS+ L L+LS V+L +S EPL ALLE+ +A+L+
Sbjct: 322 NPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERASATLQ 381
Query: 353 TLILEGCQIHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLRHTSGLSKLSLETY 412
L+ + C I QL A+LP LSHCSQLTT F N +S+ AL+ LL+H GLS L+ Y
Sbjct: 382 DLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNLTHVLY 441
Query: 413 PAPEESLNSL-VRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELH 471
P P ES + + E A L A L L E+ +P +++ PCP CG + E
Sbjct: 442 PVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGDRTFYDPEPI 501
Query: 472 LC 473
LC
Sbjct: 502 LC 503
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.326 0.140 0.435
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,458,251
Number of Sequences: 37866
Number of extensions: 817466
Number of successful extensions: 2689
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 39
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 2556
Number of HSP's gapped (non-prelim): 69
length of query: 474
length of database: 18,247,518
effective HSP length: 106
effective length of query: 368
effective length of database: 14,233,722
effective search space: 5238009696
effective search space used: 5238009696
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.