Guide to the Human Genome
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Search of human proteins with 66932990

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|66932990 folylpolyglutamate synthase isoform b [Homo
sapiens]
         (537 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|66932990 folylpolyglutamate synthase isoform b [Homo sapiens]     1103   0.0  
gi|66932984 folylpolyglutamate synthase isoform a precursor [Hom...  1103   0.0  
gi|224994221 SH3-domain binding protein 2 isoform b [Homo sapiens]     35   0.13 
gi|224994219 SH3-domain binding protein 2 isoform c [Homo sapiens]     35   0.13 
gi|170014705 SH3-domain binding protein 2 isoform a [Homo sapiens]     35   0.13 
gi|170014703 SH3-domain binding protein 2 isoform a [Homo sapiens]     35   0.13 
gi|121114296 caudal type homeobox 1 [Homo sapiens]                     35   0.17 
gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom...    33   0.50 
gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom...    33   0.50 
gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sap...    33   0.50 
gi|38201702 telomerase reverse transcriptase isoform 2 [Homo sap...    32   1.1  
gi|109633031 telomerase reverse transcriptase isoform 1 [Homo sa...    32   1.1  
gi|169207217 PREDICTED: zinc finger homeobox 2 [Homo sapiens]          32   1.9  
gi|169207592 PREDICTED: zinc finger homeobox 2 [Homo sapiens]          32   1.9  
gi|169207014 PREDICTED: zinc finger homeobox 2 [Homo sapiens]          32   1.9  
gi|133892686 hypothetical protein LOC727830 [Homo sapiens]             32   1.9  
gi|223468617 family with sequence similarity 75, member C1 [Homo...    31   2.5  
gi|223633941 hypothetical protein LOC389730 [Homo sapiens]             31   2.5  
gi|91206406 hypothetical protein LOC642265 [Homo sapiens]              31   2.5  
gi|169174618 PREDICTED: family with sequence similarity 75, memb...    31   2.5  
gi|239743732 PREDICTED: family with sequence similarity 75, memb...    31   2.5  
gi|153791826 hypothetical protein LOC26165 [Homo sapiens]              31   2.5  
gi|167234417 hypothetical protein LOC441054 [Homo sapiens]             31   2.5  
gi|146231958 hypothetical protein LOC647060 [Homo sapiens]             31   2.5  
gi|165377334 hypothetical protein LOC727905 [Homo sapiens]             31   2.5  
gi|238859651 pleckstrin homology domain containing family A memb...    30   4.3  
gi|126507091 LATS, large tumor suppressor, homolog 2 [Homo sapiens]    30   4.3  
gi|4885187 distal-less homeobox 5 [Homo sapiens]                       30   5.6  
gi|126131099 guanine nucleotide exchange factor p532 [Homo sapiens]    30   5.6  
gi|239754438 PREDICTED: hypothetical protein [Homo sapiens]            30   7.3  

>gi|66932990 folylpolyglutamate synthase isoform b [Homo sapiens]
          Length = 537

 Score = 1103 bits (2853), Expect = 0.0
 Identities = 537/537 (100%), Positives = 537/537 (100%)

Query: 1   MLNTLQTNAGYLEQVKRQRGDPQTQLEAMELYLARSGLQVEDLDRLNIIHVTGTKGKGST 60
           MLNTLQTNAGYLEQVKRQRGDPQTQLEAMELYLARSGLQVEDLDRLNIIHVTGTKGKGST
Sbjct: 1   MLNTLQTNAGYLEQVKRQRGDPQTQLEAMELYLARSGLQVEDLDRLNIIHVTGTKGKGST 60

Query: 61  CAFTECILRSYGLKTGFFSSPHLVQVRERIRINGQPISPELFTKYFWRLYHRLEETKDGS 120
           CAFTECILRSYGLKTGFFSSPHLVQVRERIRINGQPISPELFTKYFWRLYHRLEETKDGS
Sbjct: 61  CAFTECILRSYGLKTGFFSSPHLVQVRERIRINGQPISPELFTKYFWRLYHRLEETKDGS 120

Query: 121 CVSMPPYFRFLTLMAFHVFLQEKVDLAVVEVGIGGAYDCTNIIRKPVVCGVSSLGIDHTS 180
           CVSMPPYFRFLTLMAFHVFLQEKVDLAVVEVGIGGAYDCTNIIRKPVVCGVSSLGIDHTS
Sbjct: 121 CVSMPPYFRFLTLMAFHVFLQEKVDLAVVEVGIGGAYDCTNIIRKPVVCGVSSLGIDHTS 180

Query: 181 LLGDTVEKIAWQKGGIFKQGVPAFTVLQPEGPLAVLRDRAQQISCPLYLCPMLEALEEGG 240
           LLGDTVEKIAWQKGGIFKQGVPAFTVLQPEGPLAVLRDRAQQISCPLYLCPMLEALEEGG
Sbjct: 181 LLGDTVEKIAWQKGGIFKQGVPAFTVLQPEGPLAVLRDRAQQISCPLYLCPMLEALEEGG 240

Query: 241 PPLTLGLEGEHQRSNAALALQLAHCWLQRQDRHGAGEPKASRPGLLWQLPLAPVFQPTSH 300
           PPLTLGLEGEHQRSNAALALQLAHCWLQRQDRHGAGEPKASRPGLLWQLPLAPVFQPTSH
Sbjct: 241 PPLTLGLEGEHQRSNAALALQLAHCWLQRQDRHGAGEPKASRPGLLWQLPLAPVFQPTSH 300

Query: 301 MRLGLRNTEWPGRTQVLRRGPLTWYLDGAHTASSAQACVRWFRQALQGRERPSGGPEVRV 360
           MRLGLRNTEWPGRTQVLRRGPLTWYLDGAHTASSAQACVRWFRQALQGRERPSGGPEVRV
Sbjct: 301 MRLGLRNTEWPGRTQVLRRGPLTWYLDGAHTASSAQACVRWFRQALQGRERPSGGPEVRV 360

Query: 361 LLFNATGDRDPAALLKLLQPCQFDYAVFCPNLTEVSSTGNADQQNFTVTLDQVLLRCLEH 420
           LLFNATGDRDPAALLKLLQPCQFDYAVFCPNLTEVSSTGNADQQNFTVTLDQVLLRCLEH
Sbjct: 361 LLFNATGDRDPAALLKLLQPCQFDYAVFCPNLTEVSSTGNADQQNFTVTLDQVLLRCLEH 420

Query: 421 QQHWNHLDEEQASPDLWSAPSPEPGGSASLLLAPHPPHTCSASSLVFSCISHALQWISQG 480
           QQHWNHLDEEQASPDLWSAPSPEPGGSASLLLAPHPPHTCSASSLVFSCISHALQWISQG
Sbjct: 421 QQHWNHLDEEQASPDLWSAPSPEPGGSASLLLAPHPPHTCSASSLVFSCISHALQWISQG 480

Query: 481 RDPIFQPPSPPKGLLTHPVAHSGASILREAAAIHVLVTGSLHLVGGVLKLLEPALSQ 537
           RDPIFQPPSPPKGLLTHPVAHSGASILREAAAIHVLVTGSLHLVGGVLKLLEPALSQ
Sbjct: 481 RDPIFQPPSPPKGLLTHPVAHSGASILREAAAIHVLVTGSLHLVGGVLKLLEPALSQ 537


>gi|66932984 folylpolyglutamate synthase isoform a precursor [Homo
           sapiens]
          Length = 587

 Score = 1103 bits (2853), Expect = 0.0
 Identities = 537/537 (100%), Positives = 537/537 (100%)

Query: 1   MLNTLQTNAGYLEQVKRQRGDPQTQLEAMELYLARSGLQVEDLDRLNIIHVTGTKGKGST 60
           MLNTLQTNAGYLEQVKRQRGDPQTQLEAMELYLARSGLQVEDLDRLNIIHVTGTKGKGST
Sbjct: 51  MLNTLQTNAGYLEQVKRQRGDPQTQLEAMELYLARSGLQVEDLDRLNIIHVTGTKGKGST 110

Query: 61  CAFTECILRSYGLKTGFFSSPHLVQVRERIRINGQPISPELFTKYFWRLYHRLEETKDGS 120
           CAFTECILRSYGLKTGFFSSPHLVQVRERIRINGQPISPELFTKYFWRLYHRLEETKDGS
Sbjct: 111 CAFTECILRSYGLKTGFFSSPHLVQVRERIRINGQPISPELFTKYFWRLYHRLEETKDGS 170

Query: 121 CVSMPPYFRFLTLMAFHVFLQEKVDLAVVEVGIGGAYDCTNIIRKPVVCGVSSLGIDHTS 180
           CVSMPPYFRFLTLMAFHVFLQEKVDLAVVEVGIGGAYDCTNIIRKPVVCGVSSLGIDHTS
Sbjct: 171 CVSMPPYFRFLTLMAFHVFLQEKVDLAVVEVGIGGAYDCTNIIRKPVVCGVSSLGIDHTS 230

Query: 181 LLGDTVEKIAWQKGGIFKQGVPAFTVLQPEGPLAVLRDRAQQISCPLYLCPMLEALEEGG 240
           LLGDTVEKIAWQKGGIFKQGVPAFTVLQPEGPLAVLRDRAQQISCPLYLCPMLEALEEGG
Sbjct: 231 LLGDTVEKIAWQKGGIFKQGVPAFTVLQPEGPLAVLRDRAQQISCPLYLCPMLEALEEGG 290

Query: 241 PPLTLGLEGEHQRSNAALALQLAHCWLQRQDRHGAGEPKASRPGLLWQLPLAPVFQPTSH 300
           PPLTLGLEGEHQRSNAALALQLAHCWLQRQDRHGAGEPKASRPGLLWQLPLAPVFQPTSH
Sbjct: 291 PPLTLGLEGEHQRSNAALALQLAHCWLQRQDRHGAGEPKASRPGLLWQLPLAPVFQPTSH 350

Query: 301 MRLGLRNTEWPGRTQVLRRGPLTWYLDGAHTASSAQACVRWFRQALQGRERPSGGPEVRV 360
           MRLGLRNTEWPGRTQVLRRGPLTWYLDGAHTASSAQACVRWFRQALQGRERPSGGPEVRV
Sbjct: 351 MRLGLRNTEWPGRTQVLRRGPLTWYLDGAHTASSAQACVRWFRQALQGRERPSGGPEVRV 410

Query: 361 LLFNATGDRDPAALLKLLQPCQFDYAVFCPNLTEVSSTGNADQQNFTVTLDQVLLRCLEH 420
           LLFNATGDRDPAALLKLLQPCQFDYAVFCPNLTEVSSTGNADQQNFTVTLDQVLLRCLEH
Sbjct: 411 LLFNATGDRDPAALLKLLQPCQFDYAVFCPNLTEVSSTGNADQQNFTVTLDQVLLRCLEH 470

Query: 421 QQHWNHLDEEQASPDLWSAPSPEPGGSASLLLAPHPPHTCSASSLVFSCISHALQWISQG 480
           QQHWNHLDEEQASPDLWSAPSPEPGGSASLLLAPHPPHTCSASSLVFSCISHALQWISQG
Sbjct: 471 QQHWNHLDEEQASPDLWSAPSPEPGGSASLLLAPHPPHTCSASSLVFSCISHALQWISQG 530

Query: 481 RDPIFQPPSPPKGLLTHPVAHSGASILREAAAIHVLVTGSLHLVGGVLKLLEPALSQ 537
           RDPIFQPPSPPKGLLTHPVAHSGASILREAAAIHVLVTGSLHLVGGVLKLLEPALSQ
Sbjct: 531 RDPIFQPPSPPKGLLTHPVAHSGASILREAAAIHVLVTGSLHLVGGVLKLLEPALSQ 587


>gi|224994221 SH3-domain binding protein 2 isoform b [Homo sapiens]
          Length = 618

 Score = 35.4 bits (80), Expect = 0.13
 Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 10/78 (12%)

Query: 422 QHWNHLDEEQA--SPDLWSAPSPEPGGSASLLLAPH---PPHTCSASSLVFSCISHALQW 476
           + + H DE+ +   PD     SPEPG     L+ P    PP   +     FS +  A  +
Sbjct: 229 EDYEHDDEDDSYLEPD-----SPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSF 283

Query: 477 ISQGRDPIFQPPSPPKGL 494
            S+G  P+  PP P  GL
Sbjct: 284 TSKGPGPLLPPPPPKHGL 301


>gi|224994219 SH3-domain binding protein 2 isoform c [Homo sapiens]
          Length = 589

 Score = 35.4 bits (80), Expect = 0.13
 Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 10/78 (12%)

Query: 422 QHWNHLDEEQA--SPDLWSAPSPEPGGSASLLLAPH---PPHTCSASSLVFSCISHALQW 476
           + + H DE+ +   PD     SPEPG     L+ P    PP   +     FS +  A  +
Sbjct: 200 EDYEHDDEDDSYLEPD-----SPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSF 254

Query: 477 ISQGRDPIFQPPSPPKGL 494
            S+G  P+  PP P  GL
Sbjct: 255 TSKGPGPLLPPPPPKHGL 272


>gi|170014705 SH3-domain binding protein 2 isoform a [Homo sapiens]
          Length = 561

 Score = 35.4 bits (80), Expect = 0.13
 Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 10/78 (12%)

Query: 422 QHWNHLDEEQA--SPDLWSAPSPEPGGSASLLLAPH---PPHTCSASSLVFSCISHALQW 476
           + + H DE+ +   PD     SPEPG     L+ P    PP   +     FS +  A  +
Sbjct: 172 EDYEHDDEDDSYLEPD-----SPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSF 226

Query: 477 ISQGRDPIFQPPSPPKGL 494
            S+G  P+  PP P  GL
Sbjct: 227 TSKGPGPLLPPPPPKHGL 244


>gi|170014703 SH3-domain binding protein 2 isoform a [Homo sapiens]
          Length = 561

 Score = 35.4 bits (80), Expect = 0.13
 Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 10/78 (12%)

Query: 422 QHWNHLDEEQA--SPDLWSAPSPEPGGSASLLLAPH---PPHTCSASSLVFSCISHALQW 476
           + + H DE+ +   PD     SPEPG     L+ P    PP   +     FS +  A  +
Sbjct: 172 EDYEHDDEDDSYLEPD-----SPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSF 226

Query: 477 ISQGRDPIFQPPSPPKGL 494
            S+G  P+  PP P  GL
Sbjct: 227 TSKGPGPLLPPPPPKHGL 244


>gi|121114296 caudal type homeobox 1 [Homo sapiens]
          Length = 265

 Score = 35.0 bits (79), Expect = 0.17
 Identities = 23/81 (28%), Positives = 31/81 (38%), Gaps = 9/81 (11%)

Query: 424 WNHLDEEQASPDLWSAPSPEPGGSASLLLAPHP-PHTCSASSLVFSCISHALQWISQGRD 482
           ++H++   A P  W AP P P    +    P P     S +SL F               
Sbjct: 48  YSHVEPAPAPPTAWGAPFPAPKDDWAAAYGPGPAAPAASPASLAFG--------PPPDFS 99

Query: 483 PIFQPPSPPKGLLTHPVAHSG 503
           P+  PP P  GLL  P+   G
Sbjct: 100 PVPAPPGPGPGLLAQPLGGPG 120


>gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo
           sapiens]
          Length = 1188

 Score = 33.5 bits (75), Expect = 0.50
 Identities = 33/105 (31%), Positives = 38/105 (36%), Gaps = 3/105 (2%)

Query: 427 LDEEQASPDLWSAPSPEPGGSASLLLAPHPPHTCSASSLVFSCIS--HALQWISQGRDPI 484
           + E      L S PS  P     LL  P PP        V   +S  H L   S    P 
Sbjct: 154 ISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPD 213

Query: 485 FQPPSPPKGLLTHPVAHSGASILREAAAIHVLVTGSLHLVGGVLK 529
           F PP+PP   L  P     A      A+ H + T  L   GGV K
Sbjct: 214 FIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGT-RLFPPGGVTK 257


>gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo
           sapiens]
          Length = 1188

 Score = 33.5 bits (75), Expect = 0.50
 Identities = 33/105 (31%), Positives = 38/105 (36%), Gaps = 3/105 (2%)

Query: 427 LDEEQASPDLWSAPSPEPGGSASLLLAPHPPHTCSASSLVFSCIS--HALQWISQGRDPI 484
           + E      L S PS  P     LL  P PP        V   +S  H L   S    P 
Sbjct: 154 ISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPD 213

Query: 485 FQPPSPPKGLLTHPVAHSGASILREAAAIHVLVTGSLHLVGGVLK 529
           F PP+PP   L  P     A      A+ H + T  L   GGV K
Sbjct: 214 FIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGT-RLFPPGGVTK 257


>gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo
           sapiens]
          Length = 1188

 Score = 33.5 bits (75), Expect = 0.50
 Identities = 33/105 (31%), Positives = 38/105 (36%), Gaps = 3/105 (2%)

Query: 427 LDEEQASPDLWSAPSPEPGGSASLLLAPHPPHTCSASSLVFSCIS--HALQWISQGRDPI 484
           + E      L S PS  P     LL  P PP        V   +S  H L   S    P 
Sbjct: 154 ISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPD 213

Query: 485 FQPPSPPKGLLTHPVAHSGASILREAAAIHVLVTGSLHLVGGVLK 529
           F PP+PP   L  P     A      A+ H + T  L   GGV K
Sbjct: 214 FIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGT-RLFPPGGVTK 257


>gi|38201702 telomerase reverse transcriptase isoform 2 [Homo
           sapiens]
          Length = 1120

 Score = 32.3 bits (72), Expect = 1.1
 Identities = 13/29 (44%), Positives = 15/29 (51%)

Query: 272 RHGAGEPKASRPGLLWQLPLAPVFQPTSH 300
           +H AG P  SRP   W  P  PV+  T H
Sbjct: 302 QHHAGPPSTSRPPRPWDTPCPPVYAETKH 330


>gi|109633031 telomerase reverse transcriptase isoform 1 [Homo
           sapiens]
          Length = 1132

 Score = 32.3 bits (72), Expect = 1.1
 Identities = 13/29 (44%), Positives = 15/29 (51%)

Query: 272 RHGAGEPKASRPGLLWQLPLAPVFQPTSH 300
           +H AG P  SRP   W  P  PV+  T H
Sbjct: 302 QHHAGPPSTSRPPRPWDTPCPPVYAETKH 330


>gi|169207217 PREDICTED: zinc finger homeobox 2 [Homo sapiens]
          Length = 2790

 Score = 31.6 bits (70), Expect = 1.9
 Identities = 28/96 (29%), Positives = 35/96 (36%), Gaps = 19/96 (19%)

Query: 430  EQASPDLWSAPSPEPGG--------------SASLLLAPHPPHTCSASSLVFSCISHALQ 475
            +QA P   + P PE  G              S  L+L  H  H      L F  +S    
Sbjct: 1677 KQAVPPPPTPPPPEALGGGDKLACGACGKLFSNMLILKTHEEHV-HRRFLPFEALSRYAA 1735

Query: 476  WISQGRD----PIFQPPSPPKGLLTHPVAHSGASIL 507
               +  D    P+ +PP PP G L  PV H G   L
Sbjct: 1736 QFRKSYDSLYPPLAEPPKPPDGSLDSPVPHLGPPFL 1771


>gi|169207592 PREDICTED: zinc finger homeobox 2 [Homo sapiens]
          Length = 2706

 Score = 31.6 bits (70), Expect = 1.9
 Identities = 28/96 (29%), Positives = 35/96 (36%), Gaps = 19/96 (19%)

Query: 430  EQASPDLWSAPSPEPGG--------------SASLLLAPHPPHTCSASSLVFSCISHALQ 475
            +QA P   + P PE  G              S  L+L  H  H      L F  +S    
Sbjct: 1593 KQAVPPPPTPPPPEALGGGDKLACGACGKLFSNMLILKTHEEHV-HRRFLPFEALSRYAA 1651

Query: 476  WISQGRD----PIFQPPSPPKGLLTHPVAHSGASIL 507
               +  D    P+ +PP PP G L  PV H G   L
Sbjct: 1652 QFRKSYDSLYPPLAEPPKPPDGSLDSPVPHLGPPFL 1687


>gi|169207014 PREDICTED: zinc finger homeobox 2 [Homo sapiens]
          Length = 2706

 Score = 31.6 bits (70), Expect = 1.9
 Identities = 28/96 (29%), Positives = 35/96 (36%), Gaps = 19/96 (19%)

Query: 430  EQASPDLWSAPSPEPGG--------------SASLLLAPHPPHTCSASSLVFSCISHALQ 475
            +QA P   + P PE  G              S  L+L  H  H      L F  +S    
Sbjct: 1593 KQAVPPPPTPPPPEALGGGDKLACGACGKLFSNMLILKTHEEHV-HRRFLPFEALSRYAA 1651

Query: 476  WISQGRD----PIFQPPSPPKGLLTHPVAHSGASIL 507
               +  D    P+ +PP PP G L  PV H G   L
Sbjct: 1652 QFRKSYDSLYPPLAEPPKPPDGSLDSPVPHLGPPFL 1687


>gi|133892686 hypothetical protein LOC727830 [Homo sapiens]
          Length = 1347

 Score = 31.6 bits (70), Expect = 1.9
 Identities = 50/176 (28%), Positives = 65/176 (36%), Gaps = 23/176 (13%)

Query: 290 PLAPVFQPTSHMRLGLRNTEWPGRTQVLRRGPLTWYLDGAHTASSAQACVRWFRQALQ-- 347
           PL    QP SH  LG     +   T   R  P+      AH  SS       F   +Q  
Sbjct: 464 PLLFQAQPLSH--LGPECQPFISSTPQFRPTPMAQAEAQAHLQSSFPVLSPAFPSLIQNT 521

Query: 348 GRERPSGGPEVRVLLFNATGDRD----------PAALLKLLQPCQFDYAVFCPNLTEVSS 397
           G   P+   +V+ L    T   +            AL   +Q  Q  ++V  PNL + S 
Sbjct: 522 GVACPASQNKVQALSLPETQHPEWPLLRRQLEGRLALPSRVQKSQDVFSVSTPNLPQESL 581

Query: 398 TGNADQQNFTVTLDQVLLRCLEHQ------QHWNHLDEEQASPDLWSAPSPEPGGS 447
           T    + NF V+ +  L R LE        QHW +L   Q S DL       PG S
Sbjct: 582 TSILPE-NFPVSPE--LRRQLEQHIKKWIIQHWGNLGRIQESLDLMQLQDESPGTS 634


>gi|223468617 family with sequence similarity 75, member C1 [Homo
           sapiens]
          Length = 1188

 Score = 31.2 bits (69), Expect = 2.5
 Identities = 22/67 (32%), Positives = 24/67 (35%), Gaps = 26/67 (38%)

Query: 436 LWSAPSPEPGGSASLLLAPHPPHTCSASSLVFSCISHALQWISQGRDPIFQPPSPPKGLL 495
           L   PSPEP       L PHPPHT                      DP+   P PPKG  
Sbjct: 204 LLERPSPEPPA-----LFPHPPHT---------------------PDPLACSPPPPKGFT 237

Query: 496 THPVAHS 502
             P+  S
Sbjct: 238 PPPLRDS 244


>gi|223633941 hypothetical protein LOC389730 [Homo sapiens]
          Length = 1343

 Score = 31.2 bits (69), Expect = 2.5
 Identities = 21/63 (33%), Positives = 23/63 (36%), Gaps = 26/63 (41%)

Query: 440 PSPEPGGSASLLLAPHPPHTCSASSLVFSCISHALQWISQGRDPIFQPPSPPKGLLTHPV 499
           PSPEP       L PHPPHT                      DP+   P PPKG    P+
Sbjct: 196 PSPEPPA-----LFPHPPHT---------------------PDPLACSPPPPKGFTAPPL 229

Query: 500 AHS 502
             S
Sbjct: 230 RDS 232



 Score = 30.4 bits (67), Expect = 4.3
 Identities = 28/81 (34%), Positives = 36/81 (44%), Gaps = 9/81 (11%)

Query: 373 ALLKLLQPCQFDYAVFCPNLTEVSSTGNADQQNFTVTLDQVLLRCLEHQ------QHWNH 426
           AL   +Q  Q  ++V  PNL + S T    + NF V+ +  L R LE        QHW +
Sbjct: 553 ALPSRVQKSQDVFSVSTPNLPQESLTSILPE-NFPVSPE--LRRQLEQHIKKWIIQHWGN 609

Query: 427 LDEEQASPDLWSAPSPEPGGS 447
           L   Q S DL       PG S
Sbjct: 610 LGRIQESLDLMQLRDESPGTS 630


>gi|91206406 hypothetical protein LOC642265 [Homo sapiens]
          Length = 1347

 Score = 31.2 bits (69), Expect = 2.5
 Identities = 21/63 (33%), Positives = 23/63 (36%), Gaps = 26/63 (41%)

Query: 440 PSPEPGGSASLLLAPHPPHTCSASSLVFSCISHALQWISQGRDPIFQPPSPPKGLLTHPV 499
           PSPEP       L PHPPHT                      DP+   P PPKG    P+
Sbjct: 196 PSPEPPA-----LFPHPPHT---------------------PDPLACSPPPPKGFTAPPL 229

Query: 500 AHS 502
             S
Sbjct: 230 RDS 232



 Score = 30.4 bits (67), Expect = 4.3
 Identities = 28/81 (34%), Positives = 36/81 (44%), Gaps = 9/81 (11%)

Query: 373 ALLKLLQPCQFDYAVFCPNLTEVSSTGNADQQNFTVTLDQVLLRCLEHQ------QHWNH 426
           AL   +Q  Q  ++V  PNL + S T    + NF V+ +  L R LE        QHW +
Sbjct: 557 ALPSRVQKSQDVFSVSTPNLPQESLTSILPE-NFPVSPE--LRRQLEQHIKKWIIQHWGN 613

Query: 427 LDEEQASPDLWSAPSPEPGGS 447
           L   Q S DL       PG S
Sbjct: 614 LGRIQESLDLMQLRDESPGTS 634


>gi|169174618 PREDICTED: family with sequence similarity 75, member
           A4 isoform 2 [Homo sapiens]
          Length = 1272

 Score = 31.2 bits (69), Expect = 2.5
 Identities = 50/176 (28%), Positives = 65/176 (36%), Gaps = 23/176 (13%)

Query: 290 PLAPVFQPTSHMRLGLRNTEWPGRTQVLRRGPLTWYLDGAHTASSAQACVRWFRQALQ-- 347
           PL    QP SH  LG     +   T   R  P+      AH  SS       F   +Q  
Sbjct: 389 PLLFQAQPLSH--LGPECQPFISSTPQFRPTPMAQAEAQAHLQSSFPVLSPAFPSLIQNT 446

Query: 348 GRERPSGGPEVRVLLFNATGDRD----------PAALLKLLQPCQFDYAVFCPNLTEVSS 397
           G   P+   +V+ L    T   +            AL   +Q  Q  ++V  PNL + S 
Sbjct: 447 GVACPASQNKVQALSLPETQHPEWPLLRRQLEGRLALPSRVQKSQDVFSVSTPNLPQESL 506

Query: 398 TGNADQQNFTVTLDQVLLRCLEHQ------QHWNHLDEEQASPDLWSAPSPEPGGS 447
           T    + NF V+ +  L R LE        QHW +L   Q S DL       PG S
Sbjct: 507 TSILPE-NFPVSPE--LRRQLEQHIKKWIIQHWGNLGRIQESLDLMQLRDESPGTS 559


>gi|239743732 PREDICTED: family with sequence similarity 75, member
           A4 isoform 1 [Homo sapiens]
          Length = 1361

 Score = 31.2 bits (69), Expect = 2.5
 Identities = 50/176 (28%), Positives = 65/176 (36%), Gaps = 23/176 (13%)

Query: 290 PLAPVFQPTSHMRLGLRNTEWPGRTQVLRRGPLTWYLDGAHTASSAQACVRWFRQALQ-- 347
           PL    QP SH  LG     +   T   R  P+      AH  SS       F   +Q  
Sbjct: 478 PLLFQAQPLSH--LGPECQPFISSTPQFRPTPMAQAEAQAHLQSSFPVLSPAFPSLIQNT 535

Query: 348 GRERPSGGPEVRVLLFNATGDRD----------PAALLKLLQPCQFDYAVFCPNLTEVSS 397
           G   P+   +V+ L    T   +            AL   +Q  Q  ++V  PNL + S 
Sbjct: 536 GVACPASQNKVQALSLPETQHPEWPLLRRQLEGRLALPSRVQKSQDVFSVSTPNLPQESL 595

Query: 398 TGNADQQNFTVTLDQVLLRCLEHQ------QHWNHLDEEQASPDLWSAPSPEPGGS 447
           T    + NF V+ +  L R LE        QHW +L   Q S DL       PG S
Sbjct: 596 TSILPE-NFPVSPE--LRRQLEQHIKKWIIQHWGNLGRIQESLDLMQLRDESPGTS 648


>gi|153791826 hypothetical protein LOC26165 [Homo sapiens]
          Length = 1347

 Score = 31.2 bits (69), Expect = 2.5
 Identities = 50/176 (28%), Positives = 65/176 (36%), Gaps = 23/176 (13%)

Query: 290 PLAPVFQPTSHMRLGLRNTEWPGRTQVLRRGPLTWYLDGAHTASSAQACVRWFRQALQ-- 347
           PL    QP SH  LG     +   T   R  P+      AH  SS       F   +Q  
Sbjct: 464 PLLFQAQPLSH--LGPECQPFISSTPQFRPTPMAQAEAQAHLQSSFPVLSPAFPSLIQNT 521

Query: 348 GRERPSGGPEVRVLLFNATGDRD----------PAALLKLLQPCQFDYAVFCPNLTEVSS 397
           G   P+   +V+ L    T   +            AL   +Q  Q  ++V  PNL + S 
Sbjct: 522 GVACPASQNKVQALSLPETQHPEWPLLRRQLEGRLALPSRVQKSQDVFSVSTPNLPQESL 581

Query: 398 TGNADQQNFTVTLDQVLLRCLEHQ------QHWNHLDEEQASPDLWSAPSPEPGGS 447
           T    + NF V+ +  L R LE        QHW +L   Q S DL       PG S
Sbjct: 582 TSILPE-NFPVSPE--LRRQLEQHIKKWIIQHWGNLGRIQESLDLMQLRDESPGTS 634


>gi|167234417 hypothetical protein LOC441054 [Homo sapiens]
          Length = 309

 Score = 31.2 bits (69), Expect = 2.5
 Identities = 22/55 (40%), Positives = 26/55 (47%), Gaps = 7/55 (12%)

Query: 438 SAPSPEPGGSASLLLAPHPPHTCSASSLVFSCISHALQWISQGRDPIFQPPSPPK 492
           S+P  +PGG  +    P+P H  SA   V       L  IS   D IF PPS PK
Sbjct: 233 SSPGKKPGGMKAGTFDPYPSH--SADPYVAK-----LANISGKDDKIFHPPSGPK 280


>gi|146231958 hypothetical protein LOC647060 [Homo sapiens]
          Length = 1347

 Score = 31.2 bits (69), Expect = 2.5
 Identities = 21/63 (33%), Positives = 23/63 (36%), Gaps = 26/63 (41%)

Query: 440 PSPEPGGSASLLLAPHPPHTCSASSLVFSCISHALQWISQGRDPIFQPPSPPKGLLTHPV 499
           PSPEP       L PHPPHT                      DP+   P PPKG    P+
Sbjct: 196 PSPEPPA-----LFPHPPHT---------------------PDPLACSPPPPKGFTAPPL 229

Query: 500 AHS 502
             S
Sbjct: 230 RDS 232



 Score = 30.4 bits (67), Expect = 4.3
 Identities = 28/81 (34%), Positives = 36/81 (44%), Gaps = 9/81 (11%)

Query: 373 ALLKLLQPCQFDYAVFCPNLTEVSSTGNADQQNFTVTLDQVLLRCLEHQ------QHWNH 426
           AL   +Q  Q  ++V  PNL + S T    + NF V+ +  L R LE        QHW +
Sbjct: 557 ALPSRVQKSQDVFSVSTPNLPQESLTSILPE-NFPVSPE--LRRQLEQHIKKWIIQHWGN 613

Query: 427 LDEEQASPDLWSAPSPEPGGS 447
           L   Q S DL       PG S
Sbjct: 614 LGRIQESLDLMQLRDESPGTS 634


>gi|165377334 hypothetical protein LOC727905 [Homo sapiens]
          Length = 1347

 Score = 31.2 bits (69), Expect = 2.5
 Identities = 50/176 (28%), Positives = 65/176 (36%), Gaps = 23/176 (13%)

Query: 290 PLAPVFQPTSHMRLGLRNTEWPGRTQVLRRGPLTWYLDGAHTASSAQACVRWFRQALQ-- 347
           PL    QP SH  LG     +   T   R  P+      AH  SS       F   +Q  
Sbjct: 464 PLLFQAQPLSH--LGPECQPFISSTPQFRPTPMAQAEAQAHLQSSFPVLSPAFPSLIQNT 521

Query: 348 GRERPSGGPEVRVLLFNATGDRD----------PAALLKLLQPCQFDYAVFCPNLTEVSS 397
           G   P+   +V+ L    T   +            AL   +Q  Q  ++V  PNL + S 
Sbjct: 522 GVACPASQNKVQALSLPETQHPEWPLLRRQLEGRLALPSRVQKSQDVFSVSTPNLPQESL 581

Query: 398 TGNADQQNFTVTLDQVLLRCLEHQ------QHWNHLDEEQASPDLWSAPSPEPGGS 447
           T    + NF V+ +  L R LE        QHW +L   Q S DL       PG S
Sbjct: 582 TSILPE-NFPVSPE--LRRQLEQHIKKWIIQHWGNLGRIQESLDLMQLRDESPGTS 634


>gi|238859651 pleckstrin homology domain containing family A member
           4 isoform 1 [Homo sapiens]
          Length = 779

 Score = 30.4 bits (67), Expect = 4.3
 Identities = 16/39 (41%), Positives = 19/39 (48%), Gaps = 3/39 (7%)

Query: 422 QHWNHLDEEQA---SPDLWSAPSPEPGGSASLLLAPHPP 457
           QHW+     QA   SP     P   PG  AS++L P PP
Sbjct: 315 QHWSQEPRTQAHSGSPTYLQLPPRPPGTRASMVLLPGPP 353


>gi|126507091 LATS, large tumor suppressor, homolog 2 [Homo sapiens]
          Length = 1088

 Score = 30.4 bits (67), Expect = 4.3
 Identities = 26/87 (29%), Positives = 32/87 (36%), Gaps = 28/87 (32%)

Query: 431 QASPDLWSAPSPEPGGSASL---------------------LLAPHPPHTCSASSLVFSC 469
           Q SP   S   PE GG ASL                     L  PHP H  +  +     
Sbjct: 270 QRSPSFQSKTPPETGGYASLPTKGQGGPPGAGLAFPPPAAGLYVPHPHHKQAGPA----- 324

Query: 470 ISHALQWISQGRDPIFQPPSPPKGLLT 496
            +H L  +   R  +F   SPP+ LLT
Sbjct: 325 -AHQLH-VLGSRSQVFASDSPPQSLLT 349


>gi|4885187 distal-less homeobox 5 [Homo sapiens]
          Length = 289

 Score = 30.0 bits (66), Expect = 5.6
 Identities = 23/75 (30%), Positives = 33/75 (44%), Gaps = 7/75 (9%)

Query: 433 SPDLWSAPSPEPGGSA-SLLLAPHPPHTCSASSLVFSCISHALQWISQGRDPIFQPPSPP 491
           SP +W     EP GS+ SL   PH     S  S   S + ++  W +     I     PP
Sbjct: 220 SPAVW-----EPQGSSRSLSHHPHAHPPTSNQSPASSYLENSASWYTSAASSI-NSHLPP 273

Query: 492 KGLLTHPVAHSGASI 506
            G L HP+A +  ++
Sbjct: 274 PGSLQHPLALASGTL 288


>gi|126131099 guanine nucleotide exchange factor p532 [Homo sapiens]
          Length = 4861

 Score = 30.0 bits (66), Expect = 5.6
 Identities = 24/78 (30%), Positives = 38/78 (48%), Gaps = 7/78 (8%)

Query: 10   GYLEQVKRQRGDPQTQLEAMELYLARSGLQVEDLDRLNIIHVTGTKGKGSTCAFTECILR 69
            G+ E  +     PQ  + AME    R+ L++E L ++ ++ ++G + KGS        L 
Sbjct: 1608 GFKEPEESMSTSPQASIIAMEQQQLRAELRLEALHQI-LVLLSGMEEKGSIS------LA 1660

Query: 70   SYGLKTGFFSSPHLVQVR 87
               L +GF SS  L  VR
Sbjct: 1661 GSRLSSGFQSSTLLTSVR 1678


>gi|239754438 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 709

 Score = 29.6 bits (65), Expect = 7.3
 Identities = 20/45 (44%), Positives = 26/45 (57%), Gaps = 3/45 (6%)

Query: 219 RAQQISCPLYLCPMLEALEEGGPPLTLGLEGEHQRSNAALALQLA 263
           R+ Q+S    LCP +E + E   PL LGL+   QR  AAL  +LA
Sbjct: 38  RSAQLSASTSLCPAVEVVGERA-PLVLGLDLRQQR--AALDRELA 79


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.137    0.430 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,067,916
Number of Sequences: 37866
Number of extensions: 1233822
Number of successful extensions: 3452
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 29
Number of HSP's that attempted gapping in prelim test: 3405
Number of HSP's gapped (non-prelim): 63
length of query: 537
length of database: 18,247,518
effective HSP length: 107
effective length of query: 430
effective length of database: 14,195,856
effective search space: 6104218080
effective search space used: 6104218080
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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