Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 66932947
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|66932947 alpha-2-macroglobulin precursor [Homo sapiens]
(1474 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|66932947 alpha-2-macroglobulin precursor [Homo sapiens] 2947 0.0
gi|162809334 pregnancy-zone protein [Homo sapiens] 2115 0.0
gi|74271845 alpha-2-macroglobulin-like 1 [Homo sapiens] 1070 0.0
gi|239744583 PREDICTED: ovostatin 2 [Homo sapiens] 956 0.0
gi|169204289 PREDICTED: ovostatin [Homo sapiens] 914 0.0
gi|115529484 CD109 antigen isoform 1 precursor [Homo sapiens] 513 e-145
gi|227430301 CD109 antigen isoform 2 precursor [Homo sapiens] 493 e-139
gi|227430303 CD109 antigen isoform 3 precursor [Homo sapiens] 463 e-130
gi|239750255 PREDICTED: similar to ovostatin-2 [Homo sapiens] 452 e-127
gi|118600977 C3 and PZP-like, alpha-2-macroglobulin domain conta... 313 6e-85
gi|178557739 complement component 4B preproprotein [Homo sapiens] 299 1e-80
gi|67190748 complement component 4A preproprotein [Homo sapiens] 298 3e-80
gi|239740684 PREDICTED: similar to C4A protein isoform 1 [Homo s... 296 8e-80
gi|239740686 PREDICTED: similar to C4A protein isoform 2 [Homo s... 290 7e-78
gi|38016947 complement component 5 preproprotein [Homo sapiens] 268 2e-71
gi|115298678 complement component 3 precursor [Homo sapiens] 214 6e-55
gi|169218213 PREDICTED: similar to complement component C3, part... 172 2e-42
gi|239752557 PREDICTED: similar to Ovostatin homolog 2 [Homo sap... 155 4e-37
gi|169217711 PREDICTED: similar to Ovostatin homolog 2 [Homo sap... 148 4e-35
gi|239755748 PREDICTED: ovostatin [Homo sapiens] 143 1e-33
gi|239758130 PREDICTED: similar to complement component 4B (Chil... 131 4e-30
gi|169217713 PREDICTED: similar to Ovostatin homolog 2 [Homo sap... 108 3e-23
gi|239752555 PREDICTED: similar to Ovostatin homolog 2 [Homo sap... 105 2e-22
gi|169205183 PREDICTED: similar to hCG38149 [Homo sapiens] 78 7e-14
gi|239744557 PREDICTED: hypothetical protein LOC728715 [Homo sap... 78 7e-14
gi|239754277 PREDICTED: similar to Complement component 4A (Rodg... 74 1e-12
gi|169217831 PREDICTED: similar to Ovostatin homolog 2 [Homo sap... 72 3e-12
gi|239755754 PREDICTED: ovostatin 2 [Homo sapiens] 58 8e-08
gi|169214179 PREDICTED: similar to complement component 3 [Homo ... 56 2e-07
gi|55749678 ninein-like [Homo sapiens] 34 0.91
>gi|66932947 alpha-2-macroglobulin precursor [Homo sapiens]
Length = 1474
Score = 2947 bits (7639), Expect = 0.0
Identities = 1474/1474 (100%), Positives = 1474/1474 (100%)
Query: 1 MGKNKLLHPSLVLLLLVLLPTDASVSGKPQYMVLVPSLLHTETTEKGCVLLSYLNETVTV 60
MGKNKLLHPSLVLLLLVLLPTDASVSGKPQYMVLVPSLLHTETTEKGCVLLSYLNETVTV
Sbjct: 1 MGKNKLLHPSLVLLLLVLLPTDASVSGKPQYMVLVPSLLHTETTEKGCVLLSYLNETVTV 60
Query: 61 SASLESVRGNRSLFTDLEAENDVLHCVAFAVPKSSSNEEVMFLTVQVKGPTQEFKKRTTV 120
SASLESVRGNRSLFTDLEAENDVLHCVAFAVPKSSSNEEVMFLTVQVKGPTQEFKKRTTV
Sbjct: 61 SASLESVRGNRSLFTDLEAENDVLHCVAFAVPKSSSNEEVMFLTVQVKGPTQEFKKRTTV 120
Query: 121 MVKNEDSLVFVQTDKSIYKPGQTVKFRVVSMDENFHPLNELIPLVYIQDPKGNRIAQWQS 180
MVKNEDSLVFVQTDKSIYKPGQTVKFRVVSMDENFHPLNELIPLVYIQDPKGNRIAQWQS
Sbjct: 121 MVKNEDSLVFVQTDKSIYKPGQTVKFRVVSMDENFHPLNELIPLVYIQDPKGNRIAQWQS 180
Query: 181 FQLEGGLKQFSFPLSSEPFQGSYKVVVQKKSGGRTEHPFTVEEFVLPKFEVQVTVPKIIT 240
FQLEGGLKQFSFPLSSEPFQGSYKVVVQKKSGGRTEHPFTVEEFVLPKFEVQVTVPKIIT
Sbjct: 181 FQLEGGLKQFSFPLSSEPFQGSYKVVVQKKSGGRTEHPFTVEEFVLPKFEVQVTVPKIIT 240
Query: 241 ILEEEMNVSVCGLYTYGKPVPGHVTVSICRKYSDASDCHGEDSQAFCEKFSGQLNSHGCF 300
ILEEEMNVSVCGLYTYGKPVPGHVTVSICRKYSDASDCHGEDSQAFCEKFSGQLNSHGCF
Sbjct: 241 ILEEEMNVSVCGLYTYGKPVPGHVTVSICRKYSDASDCHGEDSQAFCEKFSGQLNSHGCF 300
Query: 301 YQQVKTKVFQLKRKEYEMKLHTEAQIQEEGTVVELTGRQSSEITRTITKLSFVKVDSHFR 360
YQQVKTKVFQLKRKEYEMKLHTEAQIQEEGTVVELTGRQSSEITRTITKLSFVKVDSHFR
Sbjct: 301 YQQVKTKVFQLKRKEYEMKLHTEAQIQEEGTVVELTGRQSSEITRTITKLSFVKVDSHFR 360
Query: 361 QGIPFFGQVRLVDGKGVPIPNKVIFIRGNEANYYSNATTDEHGLVQFSINTTNVMGTSLT 420
QGIPFFGQVRLVDGKGVPIPNKVIFIRGNEANYYSNATTDEHGLVQFSINTTNVMGTSLT
Sbjct: 361 QGIPFFGQVRLVDGKGVPIPNKVIFIRGNEANYYSNATTDEHGLVQFSINTTNVMGTSLT 420
Query: 421 VRVNYKDRSPCYGYQWVSEEHEEAHHTAYLVFSPSKSFVHLEPMSHELPCGHTQTVQAHY 480
VRVNYKDRSPCYGYQWVSEEHEEAHHTAYLVFSPSKSFVHLEPMSHELPCGHTQTVQAHY
Sbjct: 421 VRVNYKDRSPCYGYQWVSEEHEEAHHTAYLVFSPSKSFVHLEPMSHELPCGHTQTVQAHY 480
Query: 481 ILNGGTLLGLKKLSFYYLIMAKGGIVRTGTHGLLVKQEDMKGHFSISIPVKSDIAPVARL 540
ILNGGTLLGLKKLSFYYLIMAKGGIVRTGTHGLLVKQEDMKGHFSISIPVKSDIAPVARL
Sbjct: 481 ILNGGTLLGLKKLSFYYLIMAKGGIVRTGTHGLLVKQEDMKGHFSISIPVKSDIAPVARL 540
Query: 541 LIYAVLPTGDVIGDSAKYDVENCLANKVDLSFSPSQSLPASHAHLRVTAAPQSVCALRAV 600
LIYAVLPTGDVIGDSAKYDVENCLANKVDLSFSPSQSLPASHAHLRVTAAPQSVCALRAV
Sbjct: 541 LIYAVLPTGDVIGDSAKYDVENCLANKVDLSFSPSQSLPASHAHLRVTAAPQSVCALRAV 600
Query: 601 DQSVLLMKPDAELSASSVYNLLPEKDLTGFPGPLNDQDDEDCINRHNVYINGITYTPVSS 660
DQSVLLMKPDAELSASSVYNLLPEKDLTGFPGPLNDQDDEDCINRHNVYINGITYTPVSS
Sbjct: 601 DQSVLLMKPDAELSASSVYNLLPEKDLTGFPGPLNDQDDEDCINRHNVYINGITYTPVSS 660
Query: 661 TNEKDMYSFLEDMGLKAFTNSKIRKPKMCPQLQQYEMHGPEGLRVGFYESDVMGRGHARL 720
TNEKDMYSFLEDMGLKAFTNSKIRKPKMCPQLQQYEMHGPEGLRVGFYESDVMGRGHARL
Sbjct: 661 TNEKDMYSFLEDMGLKAFTNSKIRKPKMCPQLQQYEMHGPEGLRVGFYESDVMGRGHARL 720
Query: 721 VHVEEPHTETVRKYFPETWIWDLVVVNSAGVAEVGVTVPDTITEWKAGAFCLSEDAGLGI 780
VHVEEPHTETVRKYFPETWIWDLVVVNSAGVAEVGVTVPDTITEWKAGAFCLSEDAGLGI
Sbjct: 721 VHVEEPHTETVRKYFPETWIWDLVVVNSAGVAEVGVTVPDTITEWKAGAFCLSEDAGLGI 780
Query: 781 SSTASLRAFQPFFVELTMPYSVIRGEAFTLKATVLNYLPKCIRVSVQLEASPAFLAVPVE 840
SSTASLRAFQPFFVELTMPYSVIRGEAFTLKATVLNYLPKCIRVSVQLEASPAFLAVPVE
Sbjct: 781 SSTASLRAFQPFFVELTMPYSVIRGEAFTLKATVLNYLPKCIRVSVQLEASPAFLAVPVE 840
Query: 841 KEQAPHCICANGRQTVSWAVTPKSLGNVNFTVSAEALESQELCGTEVPSVPEHGRKDTVI 900
KEQAPHCICANGRQTVSWAVTPKSLGNVNFTVSAEALESQELCGTEVPSVPEHGRKDTVI
Sbjct: 841 KEQAPHCICANGRQTVSWAVTPKSLGNVNFTVSAEALESQELCGTEVPSVPEHGRKDTVI 900
Query: 901 KPLLVEPEGLEKETTFNSLLCPSGGEVSEELSLKLPPNVVEESARASVSVLGDILGSAMQ 960
KPLLVEPEGLEKETTFNSLLCPSGGEVSEELSLKLPPNVVEESARASVSVLGDILGSAMQ
Sbjct: 901 KPLLVEPEGLEKETTFNSLLCPSGGEVSEELSLKLPPNVVEESARASVSVLGDILGSAMQ 960
Query: 961 NTQNLLQMPYGCGEQNMVLFAPNIYVLDYLNETQQLTPEIKSKAIGYLNTGYQRQLNYKH 1020
NTQNLLQMPYGCGEQNMVLFAPNIYVLDYLNETQQLTPEIKSKAIGYLNTGYQRQLNYKH
Sbjct: 961 NTQNLLQMPYGCGEQNMVLFAPNIYVLDYLNETQQLTPEIKSKAIGYLNTGYQRQLNYKH 1020
Query: 1021 YDGSYSTFGERYGRNQGNTWLTAFVLKTFAQARAYIFIDEAHITQALIWLSQRQKDNGCF 1080
YDGSYSTFGERYGRNQGNTWLTAFVLKTFAQARAYIFIDEAHITQALIWLSQRQKDNGCF
Sbjct: 1021 YDGSYSTFGERYGRNQGNTWLTAFVLKTFAQARAYIFIDEAHITQALIWLSQRQKDNGCF 1080
Query: 1081 RSSGSLLNNAIKGGVEDEVTLSAYITIALLEIPLTVTHPVVRNALFCLESAWKTAQEGDH 1140
RSSGSLLNNAIKGGVEDEVTLSAYITIALLEIPLTVTHPVVRNALFCLESAWKTAQEGDH
Sbjct: 1081 RSSGSLLNNAIKGGVEDEVTLSAYITIALLEIPLTVTHPVVRNALFCLESAWKTAQEGDH 1140
Query: 1141 GSHVYTKALLAYAFALAGNQDKRKEVLKSLNEEAVKKDNSVHWERPQKPKAPVGHFYEPQ 1200
GSHVYTKALLAYAFALAGNQDKRKEVLKSLNEEAVKKDNSVHWERPQKPKAPVGHFYEPQ
Sbjct: 1141 GSHVYTKALLAYAFALAGNQDKRKEVLKSLNEEAVKKDNSVHWERPQKPKAPVGHFYEPQ 1200
Query: 1201 APSAEVEMTSYVLLAYLTAQPAPTSEDLTSATNIVKWITKQQNAQGGFSSTQDTVVALHA 1260
APSAEVEMTSYVLLAYLTAQPAPTSEDLTSATNIVKWITKQQNAQGGFSSTQDTVVALHA
Sbjct: 1201 APSAEVEMTSYVLLAYLTAQPAPTSEDLTSATNIVKWITKQQNAQGGFSSTQDTVVALHA 1260
Query: 1261 LSKYGAATFTRTGKAAQVTIQSSGTFSSKFQVDNNNRLLLQQVSLPELPGEYSMKVTGEG 1320
LSKYGAATFTRTGKAAQVTIQSSGTFSSKFQVDNNNRLLLQQVSLPELPGEYSMKVTGEG
Sbjct: 1261 LSKYGAATFTRTGKAAQVTIQSSGTFSSKFQVDNNNRLLLQQVSLPELPGEYSMKVTGEG 1320
Query: 1321 CVYLQTSLKYNILPEKEEFPFALGVQTLPQTCDEPKAHTSFQISLSVSYTGSRSASNMAI 1380
CVYLQTSLKYNILPEKEEFPFALGVQTLPQTCDEPKAHTSFQISLSVSYTGSRSASNMAI
Sbjct: 1321 CVYLQTSLKYNILPEKEEFPFALGVQTLPQTCDEPKAHTSFQISLSVSYTGSRSASNMAI 1380
Query: 1381 VDVKMVSGFIPLKPTVKMLERSNHVSRTEVSSNHVLIYLDKVSNQTLSLFFTVLQDVPVR 1440
VDVKMVSGFIPLKPTVKMLERSNHVSRTEVSSNHVLIYLDKVSNQTLSLFFTVLQDVPVR
Sbjct: 1381 VDVKMVSGFIPLKPTVKMLERSNHVSRTEVSSNHVLIYLDKVSNQTLSLFFTVLQDVPVR 1440
Query: 1441 DLKPAIVKVYDYYETDEFAIAEYNAPCSKDLGNA 1474
DLKPAIVKVYDYYETDEFAIAEYNAPCSKDLGNA
Sbjct: 1441 DLKPAIVKVYDYYETDEFAIAEYNAPCSKDLGNA 1474
>gi|162809334 pregnancy-zone protein [Homo sapiens]
Length = 1482
Score = 2115 bits (5480), Expect = 0.0
Identities = 1072/1481 (72%), Positives = 1236/1481 (83%), Gaps = 16/1481 (1%)
Query: 1 MGKNKLLHPSLVLLLLVLLPTDASVSGKPQYMVLVPSLLHTETTEKGCVLLSYLNETVTV 60
M K++LLH LVLLL++L +D++ S +PQYMVLVPSLLHTE +KGCVLLS+LNETVTV
Sbjct: 1 MRKDRLLHLCLVLLLILLSASDSN-STEPQYMVLVPSLLHTEAPKKGCVLLSHLNETVTV 59
Query: 61 SASLESVRGNRSLFTDLEAENDVLHCVAFAVPKSSSNEEVMFLTVQVKGPTQEFKKRTTV 120
SASLES R NRSLFTDL AE D+ HCV+F +P+ S++ EV FL++Q+KGPTQ+F+KR TV
Sbjct: 60 SASLESGRENRSLFTDLVAEKDLFHCVSFTLPRISASSEVAFLSIQIKGPTQDFRKRNTV 119
Query: 121 MVKNEDSLVFVQTDKSIYKPGQTVKFRVVSMDENFHPLNELIPLVYIQDPKGNRIAQWQS 180
+V N SLVFVQTDK +YKPGQTV+FRVVS+DENF P NELIPL+Y+++P+ NRIAQWQS
Sbjct: 120 LVLNTQSLVFVQTDKPMYKPGQTVRFRVVSVDENFRPRNELIPLIYLENPRRNRIAQWQS 179
Query: 181 FQLEGGLKQFSFPLSSEPFQGSYKVVVQKKSGGRTEHPFTVEEFVLPKFEVQVTVPKIIT 240
+LE G+ Q SFPLSSEP QGSY+VVVQ +SGGR +HPFTVEEFVLPKFEV+V VPKII+
Sbjct: 180 LKLEAGINQLSFPLSSEPIQGSYRVVVQTESGGRIQHPFTVEEFVLPKFEVKVQVPKIIS 239
Query: 241 ILEEEMNVSVCGLYTYGKPVPGHVTVSICRKYSDASDCHGEDSQAFCEKFSGQLNSHGCF 300
I++E++N++VCG YTYGKPVPG TVS+CRK S +C D Q CE+FS QLNS+GC
Sbjct: 240 IMDEKVNITVCGEYTYGKPVPGLATVSLCRKLSRVLNC---DKQEVCEEFSQQLNSNGCI 296
Query: 301 YQQVKTKVFQLKRKEYEMKLHTEAQIQEEGTVVELTGRQSSEITRTITKLSFVKVDSHFR 360
QQV TK+ Q+ +EMKL EA+I+EEGT +E+T + SEIT ++KL FVKVDSHFR
Sbjct: 297 TQQVHTKMLQITNTGFEMKLRVEARIREEGTDLEVTANRISEITNIVSKLKFVKVDSHFR 356
Query: 361 QGIPFFGQVRLVDGKGVPIPNKVIFIRGNEANYYSNATTDEHGLVQFSINTTNVMGTSLT 420
QGIPFF QV LVDGKGVPIPNK+ FI N+ANYYSNATT+E GL QFSINTT++ L
Sbjct: 357 QGIPFFAQVLLVDGKGVPIPNKLFFISVNDANYYSNATTNEQGLAQFSINTTSISVNKLF 416
Query: 421 VRVNYKDRSPCYGYQWVSEEHEEAHHTAYLVFSPSKSFVHLEPMSHELPCGHTQTVQAHY 480
VRV + C+ Y WV+E+H+ A HTA VFS S S++HLEP++ LPCGHT+T+ AHY
Sbjct: 417 VRVFTVHPNLCFHYSWVAEDHQGAQHTANRVFSLSGSYIHLEPVAGTLPCGHTETITAHY 476
Query: 481 ILNGGTLLGLKKLSFYYLIMAKGGIVRTGTHGLLVKQEDMKGHFSISIPVKSDIAPVARL 540
LN + L +LSF+YLIMAKG IVR+GTH L V+ DMKG F++S PV+SD+AP+AR+
Sbjct: 477 TLNRQAMGELSELSFHYLIMAKGVIVRSGTHTLPVESGDMKGSFALSFPVESDVAPIARM 536
Query: 541 LIYAVLPTGDVIGDSAKYDVENCLANKVDLSFSPSQSLPASHAHLRVTAAPQSVCALRAV 600
I+A+LP G+V+GDS K+++ENCLANKVDLSFSP+QS PASHAHL+V AAPQS+CALRAV
Sbjct: 537 FIFAILPDGEVVGDSEKFEIENCLANKVDLSFSPAQSPPASHAHLQVAAAPQSLCALRAV 596
Query: 601 DQSVLLMKPDAELSASSVYNLLPEKDLTGFPGPLNDQDDEDCINRHNVYI-NGITYTPVS 659
DQSVLLMKP+AELS SSVYNLL KDLT FP ++ Q++E +I NG Y P+S
Sbjct: 597 DQSVLLMKPEAELSVSSVYNLLTVKDLTNFPDNVDQQEEEQGHCPRPFFIHNGAIYVPLS 656
Query: 660 STNEKDMYSFLEDMGLKAFTNSKIRKPKMCPQLQQYEM----HGPEGLRVGFYESDVMGR 715
S NE D+YSFL+ MGLK FTNSKIRKPK C + G G +G E + +
Sbjct: 657 S-NEADIYSFLKGMGLKVFTNSKIRKPKSCSVIPSVSAGAVGQGYYGAGLGVVERPYVPQ 715
Query: 716 -GHARLVHVEE-----PHTETVRKYFPETWIWDLVVVNSAGVAEVGVTVPDTITEWKAGA 769
G ++ + P ETVR YFPETWIW+LV VNS+GVAEVGVTVPDTITEWKAGA
Sbjct: 716 LGTYNVIPLNNEQSSGPVPETVRSYFPETWIWELVAVNSSGVAEVGVTVPDTITEWKAGA 775
Query: 770 FCLSEDAGLGISSTASLRAFQPFFVELTMPYSVIRGEAFTLKATVLNYLPKCIRVSVQLE 829
FCLSEDAGLGISSTASLRAFQPFFVELTMPYSVIRGE FTLKATVLNYLPKCIRVSVQL+
Sbjct: 776 FCLSEDAGLGISSTASLRAFQPFFVELTMPYSVIRGEVFTLKATVLNYLPKCIRVSVQLK 835
Query: 830 ASPAFLAVPVEKEQAPHCICANGRQTVSWAVTPKSLGNVNFTVSAEALESQELCGTEVPS 889
ASPAFLA K + +CIC N RQT+SW VTPK+LGNVNF+VSAEA++S ELCG EV
Sbjct: 836 ASPAFLASQNTKGEESYCICGNERQTLSWTVTPKTLGNVNFSVSAEAMQSLELCGNEVVE 895
Query: 890 VPEHGRKDTVIKPLLVEPEGLEKETTFNSLLCPSGGEVSEELSLKLPPNVVEESARASVS 949
VPE RKDTVIK LLVE EG+E+E TF+S+ C SG VSE+LSLKLP NVV+ESARAS S
Sbjct: 896 VPEIKRKDTVIKTLLVEAEGIEQEKTFSSMTCASGANVSEQLSLKLPSNVVKESARASFS 955
Query: 950 VLGDILGSAMQNTQNLLQMPYGCGEQNMVLFAPNIYVLDYLNETQQLTPEIKSKAIGYLN 1009
VLGDILGSAMQN QNLLQMPYGCGEQNMVLFAPNIYVL+YLNETQQLT EIK+KA+GYL
Sbjct: 956 VLGDILGSAMQNIQNLLQMPYGCGEQNMVLFAPNIYVLNYLNETQQLTQEIKAKAVGYLI 1015
Query: 1010 TGYQRQLNYKHYDGSYSTFGERYGRNQGNTWLTAFVLKTFAQARAYIFIDEAHITQALIW 1069
TGYQRQLNYKH DGSYSTFGERYGRNQGNTWLTAFVLKTFAQAR+YIFIDEAHITQ+L W
Sbjct: 1016 TGYQRQLNYKHQDGSYSTFGERYGRNQGNTWLTAFVLKTFAQARSYIFIDEAHITQSLTW 1075
Query: 1070 LSQRQKDNGCFRSSGSLLNNAIKGGVEDEVTLSAYITIALLEIPLTVTHPVVRNALFCLE 1129
LSQ QKDNGCFRSSGSLLNNAIKGGVEDE TLSAY+TIALLEIPL VT+P+VRNALFCLE
Sbjct: 1076 LSQMQKDNGCFRSSGSLLNNAIKGGVEDEATLSAYVTIALLEIPLPVTNPIVRNALFCLE 1135
Query: 1130 SAWKTAQEGDHGSHVYTKALLAYAFALAGNQDKRKEVLKSLNEEAVKKDNSVHWERPQKP 1189
SAW A+EG HGSHVYTKALLAYAF+L G Q++ +E+L SL++EAVK+DN VHWERPQ+P
Sbjct: 1136 SAWNVAKEGTHGSHVYTKALLAYAFSLLGKQNQNREILNSLDKEAVKEDNLVHWERPQRP 1195
Query: 1190 KAPVGHFYEPQAPSAEVEMTSYVLLAYLTAQPAPTSEDLTSATNIVKWITKQQNAQGGFS 1249
KAPVGH Y+ QAPSAEVEMTSYVLLAYLTAQPAPTS DLTSATNIVKWI KQQNAQGGFS
Sbjct: 1196 KAPVGHLYQTQAPSAEVEMTSYVLLAYLTAQPAPTSGDLTSATNIVKWIMKQQNAQGGFS 1255
Query: 1250 STQDTVVALHALSKYGAATFTRTGKAAQVTIQSSGTFSSKFQVDNNNRLLLQQVSLPELP 1309
STQDTVVALHALS+YGAATFTRT K AQVT+Q S TFS+ FQVDNNN LLLQQ+SLPELP
Sbjct: 1256 STQDTVVALHALSRYGAATFTRTEKTAQVTVQDSQTFSTNFQVDNNNLLLLQQISLPELP 1315
Query: 1310 GEYSMKVTGEGCVYLQTSLKYNILPEKEEFPFALGVQTLPQTCDEPKAHTSFQISLSVSY 1369
GEY + VTGE CVYLQTS+KYNILPEKE+ PFAL VQT+PQTCD KAHTSFQISL++SY
Sbjct: 1316 GEYVITVTGERCVYLQTSMKYNILPEKEDSPFALKVQTVPQTCDGHKAHTSFQISLTISY 1375
Query: 1370 TGSRSASNMAIVDVKMVSGFIPLKPTVKMLERSNHVSRTEVSSNHVLIYLDKVSNQTLSL 1429
TG+R ASNM IVDVKMVSGFIPLKPTVKMLERS+ VSRTEVS+NHVLIY+++V+NQTLS
Sbjct: 1376 TGNRPASNMVIVDVKMVSGFIPLKPTVKMLERSSSVSRTEVSNNHVLIYVEQVTNQTLSF 1435
Query: 1430 FFTVLQDVPVRDLKPAIVKVYDYYETDEFAIAEYNAPCSKD 1470
F VLQD+PV DLKPAIVKVYDYYETDE +AEY APCS D
Sbjct: 1436 SFMVLQDIPVGDLKPAIVKVYDYYETDESVVAEYIAPCSTD 1476
>gi|74271845 alpha-2-macroglobulin-like 1 [Homo sapiens]
Length = 1454
Score = 1070 bits (2767), Expect = 0.0
Identities = 598/1476 (40%), Positives = 875/1476 (59%), Gaps = 48/1476 (3%)
Query: 13 LLLLVLLPTDASVSGKPQYMVLVPSLLHTETTEKGCVLLSYLNETVTVSASLESVRGNRS 72
LLL +L + A P Y+V +P+ L+ + +K C+ LS V + +LE+ +
Sbjct: 5 LLLGMLALSPAIAEELPNYLVTLPARLNFPSVQKVCLDLSPGYSDVKFTVTLETKDKTQK 64
Query: 73 LFTDLEAENDVLHCVAFAVPK-SSSNEEVMFLTVQVKGPTQEFKKRTTVMVKNEDSLVFV 131
L + LHC++F VP + EEV + V G F+++ V+++ + + FV
Sbjct: 65 LLEYSGLKKRHLHCISFLVPPPAGGTEEVATIRVSGVGNNISFEEKKKVLIQRQGNGTFV 124
Query: 132 QTDKSIYKPGQTVKFRVVSMDENFHPLNELIPLVYIQDPKGNRIAQWQSFQLEGGLKQFS 191
QTDK +Y PGQ V FR+V+MD NF P+N+ +V +QDP NRIAQW E G+ S
Sbjct: 125 QTDKPLYTPGQQVYFRIVTMDSNFVPVNDKYSMVELQDPNSNRIAQWLEVVPEQGIVDLS 184
Query: 192 FPLSSEPFQGSYKVVVQKKSGGRTEHPFTVEEFVLPKFEVQVTVPKIITILEEEMNVSVC 251
F L+ E G+Y V V + G+T F+VEE+VLPKF+V+V PK ++ ++E V +C
Sbjct: 185 FQLAPEAMLGTYTVAVAE---GKTFGTFSVEEYVLPKFKVEVVEPKELSTVQESFLVKIC 241
Query: 252 GLYTYGKPVPGHVTVSICRKYSDA--SDCHGEDSQAFCEKFSGQLNSHGCFYQQVKTKVF 309
YTYGKP+ G V VS+C+K + + E C SGQ + GCF V F
Sbjct: 242 CRYTYGKPMLGAVQVSVCQKANTYWYREVEREQLPDKCRNLSGQTDKTGCFSAPVDMATF 301
Query: 310 QLKRKEYEMKLHTEAQIQEEGTVVELTGRQSSEITRTITKLSFVKVDSHFRQGIPFFGQV 369
L Y +++ A + EEGT VE Q+ I+ + ++F + + PF G++
Sbjct: 302 DLIGYAYSHQINIVATVVEEGTGVEANATQNIYISPQMGSMTFEDTSNFYHPNFPFSGKI 361
Query: 370 RLVDGKGVPIPNKVIF--IRGNEANYYSNATTDEHGLVQFSINTTNVMGTSLTVRVNYKD 427
R+ + N ++F I G + TD +GL F++ T+ GT +++ ++
Sbjct: 362 RVRGHDDSFLKNHLVFLVIYGTNGTFNQTLVTDNNGLAPFTLETSGWNGTDVSLEGKFQM 421
Query: 428 RSPCYGYQWVSEEHEEAHHTAYLVFSPSKSFVHLEPMSHELPCGHTQTVQAHYILNGGTL 487
Y + V ++ A+ +S ++SF+ + ++ L CG Q V Y ++
Sbjct: 422 EDLVYNPEQVPRYYQNAYLHLRPFYSTTRSFLGIHRLNGPLKCGQPQEVLVDYYIDPADA 481
Query: 488 LGLKKLSFYYLIMAKGGIVRTGTHGLLVKQEDMKGHFSISIPVKSDIAPVARLLIYAVLP 547
+++SF Y ++ KG +V G L K++ +K FS+S+ S +AP L+IYA+ P
Sbjct: 482 SPDQEISFSYYLIGKGSLVMEGQKHLNSKKKGLKASFSLSLTFTSRLAPDPSLVIYAIFP 541
Query: 548 TGDVIGDSAKYDVENCLANKVDLSFSPSQSLPASHAHLRVTAAPQSVCALRAVDQSVLLM 607
+G V+ D ++ VE C N+V L FSPSQ LP + L++ AAP S+CALRAVD+SVLL+
Sbjct: 542 SGGVVADKIQFSVEMCFDNQVSLGFSPSQQLPGAEVELQLQAAPGSLCALRAVDESVLLL 601
Query: 608 KPDAELSASSVYNLLP-----------EKDLTGFPGPLN-DQDDEDCINRHNVYINGITY 655
+PD ELS SVY + P E D GP + Q D + + + I +
Sbjct: 602 RPDRELSNRSVYGMFPFWYGHYPYQVAEYDQCPVSGPWDFPQPLIDPMPQGHSSQRSIIW 661
Query: 656 TPVSSTNEKDMYSFLEDMGLKAFTNSKIRKPKMCPQLQQYEMHGPEGLRVGFYESDVMGR 715
P S + D++SF D+GLK +N+KI+KP C PE + + G
Sbjct: 662 RP-SFSEGTDLFSFFRDVGLKILSNAKIKKPVDCSH------RSPE-----YSTAMGAGG 709
Query: 716 GHARLVHVEEP----HTETVRKYFPETWIWDLVVVNSAGVAEVGVTVPDTITEWKAGAFC 771
GH P VR+YFPETW+WDL + ++G V VTVPD ITEWKA +FC
Sbjct: 710 GHPEAFESSTPLHQAEDSQVRQYFPETWLWDLFPIGNSGKEAVHVTVPDAITEWKAMSFC 769
Query: 772 LSEDAGLGISSTASLRAFQPFFVELTMPYSVIRGEAFTLKATVLNYLPKCIRVSVQLEAS 831
S+ G G+S T L AF+PFFV+LT+PYSV+RGE+F L AT+ NYL CIRV L S
Sbjct: 770 TSQSRGFGLSPTVGLTAFKPFFVDLTLPYSVVRGESFRLTATIFNYLKDCIRVQTDLAKS 829
Query: 832 PAFLAVPVEKEQAPHCICANGRQTVSWAVTPKSLGNVNFTVSAEALESQELCGTEVPSVP 891
+ Q C+CA+ +T W +T LG++NFT+S + L+S E CG + VP
Sbjct: 830 HEYQLESWADSQTSSCLCADEAKTHHWNITAVKLGHINFTISTKILDSNEPCGGQKGFVP 889
Query: 892 EHGRKDTVIKPLLVEPEGLEKETTFNSLLCPSGGEVSEELSLKLPPNVVEESARASVSVL 951
+ GR DT+IKP+LV+PEG+ E T +SLLCP G SE +SL+LP ++V +S +A V+VL
Sbjct: 890 QKGRSDTLIKPVLVKPEGVLVEKTHSSLLCPKGKVASESVSLELPVDIVPDSTKAYVTVL 949
Query: 952 GDILGSAMQNTQNLLQMPYGCGEQNMVLFAPNIYVLDYLNETQQLTPEIKSKAIGYLNTG 1011
GDI+G+A+QN L+QMP GCGEQNMVLFAP IYVL YL + LT EI+S+A+G+L G
Sbjct: 950 GDIMGTALQNLDGLVQMPSGCGEQNMVLFAPIIYVLQYLEKAGLLTEEIRSRAVGFLEIG 1009
Query: 1012 YQRQLNYKHYDGSYSTFGERYGRNQGNTWLTAFVLKTFAQARAYIFIDEAHITQALIWLS 1071
YQ++L YKH +GSYS FGER G GNTWLTAFV K F QA+ +IFID +I AL W++
Sbjct: 1010 YQKELMYKHSNGSYSAFGERDG--NGNTWLTAFVTKCFGQAQKFIFIDPKNIQDALKWMA 1067
Query: 1072 QRQKDNGCFRSSGSLLNNAIKGGVEDEVTLSAYITIALLEIPLTVTHPVVRNALFCLESA 1131
Q +GC+ + G+LL+ A+KGGV+DEV+L+AY+T ALLE+ V P+V L CL+++
Sbjct: 1068 GNQLPSGCYANVGNLLHTAMKGGVDDEVSLTAYVTAALLEMGKDVDDPMVSQGLRCLKNS 1127
Query: 1132 WKTAQEGDHGSHVYTKALLAYAFALAGNQDKRKEVLKSLNEEAVKKDNSVHWERPQKPKA 1191
+ +++YT+ALLAY F+LAG D R +LK L+++A+ S++W + P +
Sbjct: 1128 ATST------TNLYTQALLAYIFSLAGEMDIRNILLKQLDQQAIISGESIYWSQKPTPSS 1181
Query: 1192 PVGHFYEPQAPSAEVEMTSYVLLAYLTAQPAPTSEDLTSATNIVKWITKQQNAQGGFSST 1251
+ EP A +VE+T+Y LLA LT +P+ T +++ AT+IV W+ KQ+NA GGFSST
Sbjct: 1182 NASPWSEPAA--VDVELTAYALLAQLT-KPSLTQKEIAKATSIVAWLAKQRNAYGGFSST 1238
Query: 1252 QDTVVALHALSKYGAATFTRTGKAAQVTIQSSGTFSSKFQVDNNNRLLLQQVSLPELPGE 1311
QDTVVAL AL+KY A T + + ++S+ F F + + NRL+ QQ +LP +PG
Sbjct: 1239 QDTVVALQALAKY-ATTAYMPSEEINLVVKSTENFQRTFNIQSVNRLVFQQDTLPNVPGM 1297
Query: 1312 YSMKVTGEGCVYLQTSLKYNILPEKEEFPFALGVQTLPQTCDEPKAHTSFQISLSVSYTG 1371
Y+++ +G+GCVY+QT L+YNILP F+L V+ C++P + S +++ SY G
Sbjct: 1298 YTLEASGQGCVYVQTVLRYNILPPTNMKTFSLSVEIGKARCEQPTSPRSLTLTIHTSYVG 1357
Query: 1372 SRSASNMAIVDVKMVSGFIPLKPTVKMLERSNHVSRTEVSSNHVLIYLDKVSNQTLSLFF 1431
SRS+SNMAIV+VKM+SGF P++ T ++L + V + E ++ + IYLD++ T + F
Sbjct: 1358 SRSSSNMAIVEVKMLSGFSPMEGTNQLLLQQPLVKKVEFGTDTLNIYLDELIKNTQTYTF 1417
Query: 1432 TVLQDVPVRDLKPAIVKVYDYYETDEFAIAEYNAPC 1467
T+ Q V V +LKPA +KVYDYY DE A +Y+ PC
Sbjct: 1418 TISQSVLVTNLKPATIKVYDYYLPDEQATIQYSDPC 1453
>gi|239744583 PREDICTED: ovostatin 2 [Homo sapiens]
Length = 1394
Score = 956 bits (2471), Expect = 0.0
Identities = 536/1412 (37%), Positives = 828/1412 (58%), Gaps = 53/1412 (3%)
Query: 30 QYMVLVPSLLHTETTEKGCVLLSYLNETVTVSASLESVRGNRSLFTDLEAENDVLHCVAF 89
QY++L+PS+L + +K C L L E+V ++ SL +F + + C++F
Sbjct: 12 QYVLLIPSVLQEGSLDKACAQLFNLTESVVLTVSLNYGEVQTKIFEENVTGENFFKCISF 71
Query: 90 AVPKSSSNEEVMFLTVQVKGPTQEFKKRTTVMVKNEDSLVFVQTDKSIYKPGQTVKFRVV 149
VP++ S + + F+T KG T ++R +V +++ +++VFVQTDK YKPGQ +
Sbjct: 72 EVPQARS-DPLAFITFSAKGATLNLEERRSVAIRSRENVVFVQTDKPTYKPGQKDVNGIA 130
Query: 150 SMDENFHPLNELIPLVYIQDPKGNRIAQWQSFQLEGGLKQFSFPLSSEPFQGSYKVVVQK 209
+ + P + ++DP+ NRI QWQ+ + Q SF L SEP G Y +VV++
Sbjct: 131 QFFLDTYTFT--YPNITLKDPQNNRIFQWQNVTSFRNITQLSFQLISEPMFGDYWIVVKR 188
Query: 210 KSGGRTEHPFTVEEFVLPKFEVQVTVPKIITILEEEMNVSVCGLYTYGKPVPGHVTVSIC 269
S H F V+ +VLPKFEV V P+ +TI ++E V VC YT+G+PV G + +C
Sbjct: 189 NSRKTVTHQFAVKRYVLPKFEVTVNAPQTVTISDDEFQVDVCAKYTFGQPVQGKTQIRVC 248
Query: 270 RKYSDASDCHGEDSQAFCEKFSGQLNSHGCFYQQVKTKVFQLKRKEYEMKLHTEAQIQEE 329
R+Y +S+C D++ CE+F QL + GC Q V TKVFQL R M H + E
Sbjct: 249 REYFSSSNCEKNDNE-ICEQFIAQLEN-GCVSQIVNTKVFQLYRSGLFMTFHVAVIVTEF 306
Query: 330 GT---VVELTGRQSSEITRTITKLSFVKVDSHFRQGIPFFGQVRLVDGKGVPIPNKVIFI 386
GT ++++ + S IT+ + ++F +D+ +R+GI +FG ++ D VP+ NK++ +
Sbjct: 307 GTGNYCMQISEKTSVFITQLLGTVNFENMDTFYRRGISYFGTLKFSDPNNVPMVNKLLQL 366
Query: 387 RGNEANYYSNATTDEHGLVQFSINTTNVMGTSLTVRVNYKDRSPCYGYQWVSEEHEEAHH 446
N+ + N TTDE+G QFSI+T+++ ++ Y CY W++ ++ +AH
Sbjct: 367 ELND-EFIGNYTTDENGEAQFSIDTSDIFDPEFNLKATYVRPKSCYLPSWLTPQYLDAHF 425
Query: 447 TAYLVFSPSKSFVHLEPMSHELPCGHTQTVQAHYILNGGTLLGLKKLSFYYLIMAKGGIV 506
+S + SF+ + P +L C H + V HY LN + F+YL+
Sbjct: 426 LVSRFYSRTNSFLKIVPEPKQLECNHQKVVTVHYSLNSEAYEDDSNVKFFYLVSLSHD-- 483
Query: 507 RTGTHGLLVKQEDM----KGHFSISIPVKSDIAPVARLLIYAVLPTGDVIGDSAKYDVEN 562
+G + + G+FS + + +D+AP A L +Y + P+G+++ DS ++ V+
Sbjct: 484 -SGNFQHRISSSPIYTAWNGNFSFPLSISADLAPAAVLFVYTLHPSGEIVADSVRFQVDK 542
Query: 563 CLANKVDLSFSPSQSLPASHAHLRVTAAPQSVCALRAVDQSVLLMKPDAELSASSVYNLL 622
C +KV++ FS Q LP S+A L + AAP CAL AVD +VLL+K + +LSA SVYN++
Sbjct: 543 CFKHKVNIKFSNEQGLPGSNASLYLQAAPVLFCALGAVDGNVLLLKSEQQLSAESVYNMV 602
Query: 623 PEKDLTGF---PGPLNDQDDEDCINRHNVYINGITYTPVSSTNEKDMYSFLEDMGLKAFT 679
P + G+ L+D ++ CI + +++ NG+ YTPVS+ + D+Y+ + +MGLK FT
Sbjct: 603 PSIEPYGYFYHGLNLDDGKEDPCIPQRDMFYNGLYYTPVSNYGDGDIYNIVRNMGLKVFT 662
Query: 680 NSKIRKPKMCPQLQQYEMHGPEGLRVGFY------ESDVMGRGHARLVHVEEPHTETVRK 733
N RKP++C ++ + P L Y S + RG +VE+ +TVR
Sbjct: 663 NLHYRKPEVCVMERRLPLPKPLYLETENYGPMHSVPSRIACRGE-NADYVEQAIIQTVRT 721
Query: 734 YFPETWIWDLVVVNSAGVAEVGVTVPDTITEWKAGAFCLSEDAGLGISSTASLRAFQPFF 793
FPETW+WDLV V+S+G A + +PDTIT+W+A FC++ D G GISST +L QPFF
Sbjct: 722 NFPETWMWDLVSVDSSGSANLSFLIPDTITQWEASGFCVNGDVGFGISSTTTLEVSQPFF 781
Query: 794 VELTMPYSVIRGEAFTLKATVLNYLPKCIRVSVQLEASPAFLA-VPVEKEQAPHCICANG 852
+E+ P+SV++ E F L +YL C+ +SVQ+E S + A + K I A G
Sbjct: 782 IEIASPFSVVQNEQFDLIVNAFSYLNTCVEISVQVEESQNYEANINTWKINGSEVIQAGG 841
Query: 853 RQTVSWAVTPKSLGNVNFTVSAEALESQELCGTEVPSVPEHGRKDTVIKPLLVEPEGLEK 912
R+T W + PK LG VN TV AE+ +S C E + KDTV+K LVEPEG+EK
Sbjct: 842 RKTNIWTIIPKKLGKVNITVVAESKQS-SACPNEGMEQQKLNWKDTVVKSFLVEPEGIEK 900
Query: 913 ETTFNSLLCPSGGEVSEELSLKLPPNVVEESARASVSVLGDILGSAMQNTQNLLQMPYGC 972
E T + L+C G + S++ L LP +VVE SAR +V+GDILG AMQN +LQMPYG
Sbjct: 901 ERTQSFLICTEGAKASKQGVLDLPNDVVEGSARGFFTVVGDILGLAMQNLV-VLQMPYGG 959
Query: 973 GEQNMVLFAPNIYVLDYLNETQQLTPEIKSKAIGYLNTGYQRQLNYKHYDGSYSTFGERY 1032
GEQN L A + YVLDYL T+QLT E++SKA L+ GYQRQL++K+ DGSYS F ++
Sbjct: 960 GEQNAALLASDTYVLDYLKSTEQLTEEVQSKAFFLLSNGYQRQLSFKNSDGSYSVFWQQ- 1018
Query: 1033 GRNQGNTWLTAFVLKTFAQARAYIFIDEAHITQALIWLSQRQKDNGCFRSSGSLLNNAIK 1092
+G+ WL+A KT + + ++FIDE Q LIWLS +QK +GCF++ G L N+A +
Sbjct: 1019 -NQKGSIWLSALTFKTLERMKKFVFIDENVQKQTLIWLSSQQKTSGCFKNDGQLFNHAWE 1077
Query: 1093 GGVEDEVTLSAYITIALLEIPLTVTHPVVRNALFCLESAWKTAQEGDHGSHVYTKALLAY 1152
GG E++++L+AY+ E L T P +RNALFCLE+A + ++ Y A+LAY
Sbjct: 1078 GGDEEDISLTAYVVGMFFEAGLNSTFPALRNALFCLEAALDSGV-----TNGYNHAILAY 1132
Query: 1153 AFALAGNQDKRKEVLKSLNEEAVKKDNSVHWERPQKPKAPVGHFYEPQAPSAEVEMTSYV 1212
AFALAG + + + +L++L++ A K +N ++WER +KPK + P APSA+ E + YV
Sbjct: 1133 AFALAGKEKQVESLLQTLDQSATKLNNVIYWERERKPKTEEFPSFIPWAPSAQTEKSCYV 1192
Query: 1213 LLAYLTAQPAPTSEDLTSATNIVKWITKQQNAQGGFSSTQDTVVALHALSKYG-AATFTR 1271
LLA ++ + DLT A+ IV+W+ +Q N+ GGFSS Q V L ++ G F++
Sbjct: 1193 LLAVISRK----IPDLTYASKIVQWLAQQMNSHGGFSSNQVINVGLILIAICGEEGLFSK 1248
Query: 1272 TGKAAQVTIQSSGTFSSKFQVDNNNRLLLQQVSLPELPGEYSMKVTGEGCVYLQTSLKYN 1331
Q T+ S SS+ Q + +NRLL+Q+ + + PG+Y++ V G GC ++Q +LKYN
Sbjct: 1249 N----QNTVTFSSEGSSEIQFNGHNRLLVQRSEVTQAPGQYTVDVEGRGCTFIQATLKYN 1304
Query: 1332 ILPEKEEFPFALGVQTLPQTCDEPKAHTSFQISLSVSYTGSRSASNMAIVDVKMVSGFIP 1391
+L K+ F+L ++ + + + T F +++++ YTG R+ S+M ++DVKM+SGF
Sbjct: 1305 VLLPKKASGFSLSLEIV-----KNYSLTVFDLTVNLKYTGIRNKSSMVVIDVKMLSGF-- 1357
Query: 1392 LKPTVKMLERSNHVSRTEVSSNHVLIYLDKVS 1423
PT+ +E N+ S + + Y DK++
Sbjct: 1358 -TPTMSSIEEVNNRSLIFHHKDSYIEYKDKIN 1388
>gi|169204289 PREDICTED: ovostatin [Homo sapiens]
Length = 1353
Score = 914 bits (2363), Expect = 0.0
Identities = 516/1355 (38%), Positives = 797/1355 (58%), Gaps = 53/1355 (3%)
Query: 91 VPKSSSNEEVMFLTVQVKGPTQEFKKRTTVMVKNEDSLVFVQTDKSIYKPGQTVKFRVVS 150
VP++ S + + F+T KG T ++R +V +++ +++VFVQTDK YKPGQ +
Sbjct: 24 VPQARS-DPLAFITFSAKGATLNLEERRSVAIRSRENVVFVQTDKPTYKPGQKDVNGIAQ 82
Query: 151 MDENFHPLNELIPLVYIQDPKGNRIAQWQSFQLEGGLKQFSFPLSSEPFQGSYKVVVQKK 210
+ + P + ++DP+ NRI Q Q+ + Q SF L SEP G Y +VV++
Sbjct: 83 FFLDTYTFT--YPNITLKDPQNNRIFQRQNVTSFRNITQLSFQLISEPMFGDYWIVVKRN 140
Query: 211 SGGRTEHPFTVEEFVLPKFEVQVTVPKIITILEEEMNVSVCGLYTYGKPVPGHVTVSICR 270
S H F V+ +VLPKFEV V P+ +TI ++E V VC Y +G+PV G + +CR
Sbjct: 141 SRETVTHQFAVKRYVLPKFEVTVNAPQTVTISDDEFQVDVCAKYNFGQPVQGETQIRVCR 200
Query: 271 KYSDASDCHGEDSQAFCEKFSGQLNSHGCFYQQVKTKVFQLKRKEYEMKLHTEAQIQEEG 330
+Y +S+C +++ CE+F QL +GC Q V TKVFQL R M H + E G
Sbjct: 201 EYFSSSNCEKNENE-ICEQFIAQL-ENGCVSQIVNTKVFQLYRSGLFMTFHVAVIVTESG 258
Query: 331 T---VVELTGRQSSEITRTITKLSFVKVDSHFRQGIPFFGQVRLVDGKGVPIPNKVIFIR 387
T ++++ + S IT+ + ++F +D+ +R+GI +FG ++ D VP+ NK++ +
Sbjct: 259 TGNYFMQISEKTSVFITQLLGTVNFENMDTFYRRGISYFGTLKFSDPNNVPMVNKLLQLE 318
Query: 388 GNEANYYSNATTDEHGLVQFSINTTNVMGTSLTVRVNYKDRSPCYGYQWVSEEHEEAHHT 447
N+ + N TTDE+G QFSI+T+++ ++ Y CY W++ ++ +AH
Sbjct: 319 LND-EFIGNYTTDENGEAQFSIDTSDIFDPEFNLKATYVRPESCYLPSWLTPQYLDAHFL 377
Query: 448 AYLVFSPSKSFVHLEPMSHELPCGHTQTVQAHYILNGGTLLGLKKLSFYYLIMAKGGIVR 507
+S + SF+ + P +L C + V HY LN + F+YL+
Sbjct: 378 VSRFYSRTNSFLKIVPEPKQLECNQQKVVTVHYSLNSEAYEDDSNVKFFYLVSLSHD--- 434
Query: 508 TGTHGLLVKQEDM----KGHFSISIPVKSDIAPVARLLIYAVLPTGDVIGDSAKYDVENC 563
+G + + G+FS I + +D+AP A L +Y + P+G+++ DS ++ V+ C
Sbjct: 435 SGNFQHRISSSPIYTAWNGNFSFPISISADLAPAAVLFVYTLHPSGEIVADSVRFQVDKC 494
Query: 564 LANKVDLSFSPSQSLPASHAHLRVTAAPQSVCALRAVDQSVLLMKPDAELSASSVYNLLP 623
+KV++ FS Q LP S+A L + AAP CALRAVD++VLL+K + +LSA SVYN++P
Sbjct: 495 FKHKVNIKFSNEQGLPGSNASLCLQAAPVLFCALRAVDRNVLLLKSEQQLSAESVYNMVP 554
Query: 624 EKDLTGF---PGPLNDQDDEDCINRHNVYINGITYTPVSSTNEKDMYSFLEDMGLKAFTN 680
+ G+ L+D ++ CI + +++ NG+ YTPVS+ + D+Y+ + +MGLK FTN
Sbjct: 555 SIEPYGYFYHGLNLDDGKEDPCIPQRDMFYNGLYYTPVSNYGDGDIYNIVRNMGLKVFTN 614
Query: 681 SKIRKPKMCPQLQQYEMHGPEGLRVGFY------ESDVMGRGHARLVHVEEPHTETVRKY 734
RKP++C ++ + P L Y S + RG +VE+ +TVR
Sbjct: 615 LHYRKPEVCVMERRLPLPKPLYLETENYGPMRSVPSRIACRGE-NADYVEQAIIQTVRTN 673
Query: 735 FPETWIWDLVVVNSAGVAEVGVTVPDTITEWKAGAFCLSEDAGLGISSTASLRAFQPFFV 794
FPETW+WDLV V+S+G A + +PDTIT+W+A FC++ D G GISST +L QPFF+
Sbjct: 674 FPETWMWDLVSVDSSGSANLSFLIPDTITQWEASGFCVNGDVGFGISSTTTLEVSQPFFI 733
Query: 795 ELTMPYSVIRGEAFTLKATVLNYLPKCIRVSVQLEASPAFLA-VPVEKEQAPHCICANGR 853
E+ P+SV++ E F L V +Y C+ +SVQ+E S + A + K I A GR
Sbjct: 734 EIASPFSVVQNEQFDLIVNVFSYRNTCVEISVQVEESQNYEANIHTLKINGSEVIQAGGR 793
Query: 854 QTVSWAVTPKSLGNVNFTVSAEALESQELCGTEVPSVPEHGRKDTVIKPLLVEPEGLEKE 913
+T W + PK LG VN TV AE+ +S C E + KDTV++ LVEPEG+EKE
Sbjct: 794 KTNVWTIIPKKLGKVNITVVAESKQS-SACPNEGMEQQKLNWKDTVVQSFLVEPEGIEKE 852
Query: 914 TTFNSLLCPSGGEVSEELSLKLPPNVVEESARASVSVLGDILGSAMQNTQNLLQMPYGCG 973
T + L+C G + S++ L LP +VVE SAR +V+GDILG A+QN +LQMPYG G
Sbjct: 853 RTQSFLICTEGAKASKQGVLDLPNDVVEGSARGFFTVVGDILGLALQNLV-VLQMPYGSG 911
Query: 974 EQNMVLFAPNIYVLDYLNETQQLTPEIKSKAIGYLNTGYQRQLNYKHYDGSYSTFGERYG 1033
EQN L A + YVLDYL T+QLT E++SKA L+ GYQRQL++K+ DGSYS F ++
Sbjct: 912 EQNAALLASDTYVLDYLKSTEQLTEEVQSKAFFLLSNGYQRQLSFKNSDGSYSVFWQQ-- 969
Query: 1034 RNQGNTWLTAFVLKTFAQARAYIFIDEAHITQALIWLSQRQKDNGCFRSSGSLLNNAIKG 1093
+G+ L+A KT + + Y+FIDE Q LIWLS +QK +GCF++ G L N+A +G
Sbjct: 970 SQKGSIXLSALTFKTLERMKKYVFIDENVQKQTLIWLSSQQKTSGCFKNDGQLFNHAWEG 1029
Query: 1094 GVEDEVTLSAYITIALLEIPLTVTHPVVRNALFCLESAWKTAQEGDHGSHVYTKALLAYA 1153
G E++++L+AY+ E L T P +RNALFCLE+A + ++ Y A+LAYA
Sbjct: 1030 GDEEDISLTAYVVGMFFEAGLNFTFPALRNALFCLEAALDSGV-----TNGYNHAILAYA 1084
Query: 1154 FALAGNQDKRKEVLKSLNEEAVKKDNSVHWERPQKPKAPVGHFYEPQAPSAEVEMTSYVL 1213
FALAG + + + +L++L++ A K +N ++WER +KPK + P APSA+ E + YVL
Sbjct: 1085 FALAGKEKQVESLLQTLDQSAPKLNNVIYWERERKPKTEEFPSFIPWAPSAQTEKSCYVL 1144
Query: 1214 LAYLTAQPAPTSEDLTSATNIVKWITKQQNAQGGFSSTQDTVVALHALSKYGAATFTRTG 1273
LA ++ + DLT A+ IV+W+ ++ N+ GGFSS Q V L ++ R
Sbjct: 1145 LAVISRK----IPDLTYASKIVQWLAQRMNSHGGFSSNQVINVGLILIAICLMQKLARGE 1200
Query: 1274 KAAQVTIQSSGTFSSK-----FQVDNNNRLLLQQVSLPELPGEYSMKVTGEGCVYLQTSL 1328
+ Q++ TFSS+ FQV+ +NRLL+Q+ + + PGEY++ V G GC ++Q +L
Sbjct: 1201 EGLFSKDQNTVTFSSEGSSEIFQVNGHNRLLVQRSEVTQAPGEYTVDVEGHGCTFIQATL 1260
Query: 1329 KYNILPEKEEFPFALGVQTLPQTCDEPKAHTSFQISLSVSYTGSRSASNMAIVDVKMVSG 1388
KYN+L K+ F+L ++ + + + T+F +++++ YTG R+ S+M ++DVKM+SG
Sbjct: 1261 KYNVLLPKKASGFSLSLEIV-----KNYSSTAFDLTVTLKYTGIRNKSSMVVIDVKMLSG 1315
Query: 1389 FIPLKPTVKMLERSNHVSRTEVSSNHVLIYLDKVS 1423
F PT+ +E N+ S + + Y DK++
Sbjct: 1316 F---TPTMSSIEEVNNRSLIFQHKDSYIEYKDKIN 1347
>gi|115529484 CD109 antigen isoform 1 precursor [Homo sapiens]
Length = 1445
Score = 513 bits (1321), Expect = e-145
Identities = 434/1508 (28%), Positives = 707/1508 (46%), Gaps = 179/1508 (11%)
Query: 15 LLVLLPTDASVSGKPQYMVLVPSLLHTE-TTEKGCVLLSYLNETVTVSASLESVRGNRSL 73
LL + +V+ P+++V P ++ G LL + VTV A L N ++
Sbjct: 12 LLCVCTAALAVAPGPRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKAELLKTASNLTV 71
Query: 74 FTDLEAENDVLHCVAF---AVPKSSSNEEVMFLTVQVKGPTQE---FKKRTTVMVKNEDS 127
LEAE V +F +P N ++V G TQ+ F T + + +
Sbjct: 72 SV-LEAEG-VFEKGSFKTLTLPSLPLNSADEIYELRVTGRTQDEILFSNSTRLSFETKRI 129
Query: 128 LVFVQTDKSIYKPGQTVKFRVVSMDENFHPLNELIPLVYIQDPKGNRIAQWQSFQLEGGL 187
VF+QTDK++YKP Q VKFR+V++ +F P + ++ I+DPK N I QW S Q + G+
Sbjct: 130 SVFIQTDKALYKPKQEVKFRIVTLFSDFKPYKTSLNIL-IKDPKSNLIQQWLSQQSDLGV 188
Query: 188 KQFSFPLSSEPFQGSYKVVVQKKSGGRTEHPFTVEEFVLPKFEVQVTVPKIITILEEEMN 247
+F LSS P G + + VQ + F V E+VLPKFEV + P ++ + +N
Sbjct: 189 ISKTFQLSSHPILGDWSIQVQVNDQTYYQS-FQVSEYVLPKFEVTLQTPLYCSMNSKHLN 247
Query: 248 VSVCGLYTYGKPVPGHVTVSICRKYSDASDCHGEDSQAFCEKFSGQLNSHGCFYQQVKTK 307
++ YTYGKPV G VT++ + S + + K +G N F +
Sbjct: 248 GTITAKYTYGKPVKGDVTLT----FLPLSFWGKKKNITKTFKINGSANFS--FNDEEMKN 301
Query: 308 VFQLKR--KEYEMKLHTEAQIQEEGTVVE-LTGRQSSEITRTITK-----LSFVKVDSHF 359
V EY + L + ++ TV E +TG + T K + F +
Sbjct: 302 VMDSSNGLSEY-LDLSSPGPVEILTTVTESVTGISRNVSTNVFFKQHDYIIEFFDYTTVL 360
Query: 360 RQGIPFFGQVRLVDGKGVPIP------NKVIFI-RGNEANYYSNATTDEHGLVQFS-INT 411
+ + F V++ G + N VI + + N Y+S + + + IN
Sbjct: 361 KPSLNFTATVKVTRADGNQLTLEERRNNVVITVTQRNYTEYWSGSNSGNQKMEAVQKINY 420
Query: 412 TNVMGTSLTVRVNYKDRSPCYGYQ----WVSEEHEEAHHTAYLVFSPSKSFVHLEPMSHE 467
T + S T ++ + Q ++ + A H+ + SPSK+++ L+
Sbjct: 421 T--VPQSGTFKIEFPILEDSSELQLKAYFLGSKSSMAVHSLFK--SPSKTYIQLKTRDEN 476
Query: 468 LPCGHTQTVQAHYILNGGTLLGLKKLSFYYLIMAKGGIVRTGTHGLLVKQEDMKGHFSIS 527
+ G + +++G L K+LS Y+++++G +V G + S
Sbjct: 477 IKVGSPFEL----VVSGNKRL--KELS--YMVVSRGQLVAVGKQNSTM----------FS 518
Query: 528 IPVKSDIAPVARLLIYAVLPTGDVIGDSAKYDVENCLANKVDLSFSPSQSLPASHAHLRV 587
+ ++ P A +++Y + G++I D K V+ NK+ L +S ++ P+ LR+
Sbjct: 519 LTPENSWTPKACVIVYYIEDDGEIISDVLKIPVQLVFKNKIKLYWSKVKAEPSEKVSLRI 578
Query: 588 TAA-PQSVCALRAVDQSVLLMKPDAELSASSVYNLLPEKDLTGFPGPLNDQDDEDCINRH 646
+ P S+ + AVD+SV LM +++ +V + L + + G
Sbjct: 579 SVTQPDSIVGIVAVDKSVNLMNASNDITMENVVHELELYNTGYYLG-------------- 624
Query: 647 NVYINGITYTPVSSTNEKDMYSFLEDMGLKAFTNSKIRKPKMCPQLQQYEMHGPEGLRVG 706
+++N ++ ++ GL T++ + K + E
Sbjct: 625 -MFMNS--------------FAVFQECGLWVLTDANLTKDYIDGVYDNAE---------- 659
Query: 707 FYESDVMGRGHARLVHVEE------PHTETVRKYFPETWIWDLVVVNSAGVAEVGVTVPD 760
Y M +V + + PH VRK+FPETWIW + E VTVPD
Sbjct: 660 -YAERFMEENEGHIVDIHDFSLGSSPH---VRKHFPETWIWLDTNMGYRIYQEFEVTVPD 715
Query: 761 TITEWKAGAFCLSEDAGLGISST-ASLRAFQPFFVELTMPYSVIRGEAFTLKATVLNYLP 819
+IT W A F +SED GLG+++T L+AFQPFF+ L +PYSVIRGE F L+ T+ NYL
Sbjct: 716 SITSWVATGFVISEDLGLGLTTTPVELQAFQPFFIFLNLPYSVIRGEEFALEITIFNYLK 775
Query: 820 KCIRVSVQLEASPAFLAVPVEKE------QAPHCICANGRQTVSWAVTPKSLGNVNFTVS 873
V V +E S F + E Q + + TV + + P LG + TV+
Sbjct: 776 DATEVKVIIEKSDKFDILMTSNEINATGHQQTLLVPSEDGATVLFPIRPTHLGEIPITVT 835
Query: 874 AEALESQELCGTEVPSVPEHGRKDTVIKPLLVEPEGLEKETTFNSLLCPSGGEVS---EE 930
A + + D V + +LV+ EG+EK + + LL + + +
Sbjct: 836 ALSPTAS----------------DAVTQMILVKAEGIEKSYSQSILLDLTDNRLQSTLKT 879
Query: 931 LSLKLPPNVVEESARASVSVLGDILGSAMQNTQNLLQMPYGCGEQNMVLFAPNIYVLDYL 990
LS PPN V S R ++ +GD+LG ++ +L++MPYGCGEQNM+ FAPNIY+LDYL
Sbjct: 880 LSFSFPPNTVTGSERVQITAIGDVLGPSINGLASLIRMPYGCGEQNMINFAPNIYILDYL 939
Query: 991 NETQQLTPEIKSKAIGYLNTGYQRQLNYKHYDGSYSTFGERYGRNQGNTWLTAFVLKTFA 1050
+ +QLT +K KA+ ++ GYQR+L Y+ DGS+S FG G+TWL+AFVL+ F
Sbjct: 940 TKKKQLTDNLKEKALSFMRQGYQRELLYQREDGSFSAFGNY--DPSGSTWLSAFVLRCFL 997
Query: 1051 QARAYIFIDEAHITQALIWLSQRQKDNGCFRSSGSLLNNAIKGGVEDEVTLSAYITIALL 1110
+A YI ID+ + + WL QK NG F G ++++ ++GG + VTL+AYI +LL
Sbjct: 998 EADPYIDIDQNVLHRTYTWLKGHQKSNGEFWDPGRVIHSELQGGNKSPVTLTAYIVTSLL 1057
Query: 1111 EIPLTVTHPVVRNALFCLESAWKTAQEGDHGSHVYTKALLAYAFALAGNQDKRKEVLKSL 1170
+ V+ ++ LES + S YT AL+ YA + G+ K KE L L
Sbjct: 1058 GYRKYQPNIDVQESIHFLESEFSRGI-----SDNYTLALITYALSSVGS-PKAKEALNML 1111
Query: 1171 NEEAVKKDNSVHWERPQKPKAPVGHFYEPQAPSAEVEMTSYVLLAYLTAQPAPTSEDLTS 1230
A ++ W ++ + ++P+ S ++E+ +Y LL++ TSE +
Sbjct: 1112 TWRAEQEGGMQFW---VSSESKLSDSWQPR--SLDIEVAAYALLSHFL--QFQTSEGIP- 1163
Query: 1231 ATNIVKWITKQQNAQGGFSSTQDTVVALHALSKYGAATFT-RTGKAAQVTIQSSGTFSSK 1289
I++W+++Q+N+ GGF+STQDT VAL ALS++ A T RT VT SS + K
Sbjct: 1164 ---IMRWLSRQRNSLGGFASTQDTTVALKALSEFAALMNTERTNIQVTVTGPSSPS-PVK 1219
Query: 1290 FQVDNNNRLLLQQVSLPEL-PGEYSMKVTGEGCVYLQTSLKYNI-----------LPEKE 1337
F +D +NRLLLQ L + P ++ G G Q ++ YN+ + +E
Sbjct: 1220 FLIDTHNRLLLQTAELAVVQPTAVNISANGFGFAICQLNVVYNVKASGSSRRRRSIQNQE 1279
Query: 1338 EFPFALGVQTLPQTCDEPKAHTSFQISLSVSYTGSRSASNMAIVDVKMVSGFIPLKPTVK 1397
F + V+ + H + S S G S MA+++V ++SGF+ +
Sbjct: 1280 AFDLDVAVKENKDDLN----HVDLNVCTSFSGPG---RSGMALMEVNLLSGFMVPSEAIS 1332
Query: 1398 MLERSNHVSRTEVSSNHVLIYLDKVSNQTLSLFFTVLQDVPVRDLKPAIVKVYDYYETDE 1457
+ S V + E + +YLD V+ + +++ V + + A V + DYYE
Sbjct: 1333 L---SETVKKVEYDHGKLNLYLDSVNETQFCVNIPAVRNFKVSNTQDASVSIVDYYEPRR 1389
Query: 1458 FAIAEYNA 1465
A+ YN+
Sbjct: 1390 QAVRSYNS 1397
>gi|227430301 CD109 antigen isoform 2 precursor [Homo sapiens]
Length = 1428
Score = 493 bits (1269), Expect = e-139
Identities = 425/1507 (28%), Positives = 696/1507 (46%), Gaps = 194/1507 (12%)
Query: 15 LLVLLPTDASVSGKPQYMVLVPSLLHTE-TTEKGCVLLSYLNETVTVSASLESVRGNRSL 73
LL + +V+ P+++V P ++ G LL + VTV A L N ++
Sbjct: 12 LLCVCTAALAVAPGPRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKAELLKTASNLTV 71
Query: 74 FTDLEAENDVLHCVAF---AVPKSSSNEEVMFLTVQVKGPTQE---FKKRTTVMVKNEDS 127
LEAE V +F +P N ++V G TQ+ F T + + +
Sbjct: 72 SV-LEAEG-VFEKGSFKTLTLPSLPLNSADEIYELRVTGRTQDEILFSNSTRLSFETKRI 129
Query: 128 LVFVQTDKSIYKPGQTVKFRVVSMDENFHPLNELIPLVYIQDPKGNRIAQWQSFQLEGGL 187
VF+QTDK++YKP Q VKFR+V++ +F P + ++ I+DPK N I QW S Q + G+
Sbjct: 130 SVFIQTDKALYKPKQEVKFRIVTLFSDFKPYKTSLNIL-IKDPKSNLIQQWLSQQSDLGV 188
Query: 188 KQFSFPLSSEPFQGSYKVVVQKKSGGRTEHPFTVEEFVLPKFEVQVTVPKIITILEEEMN 247
+F LSS P G + + VQ + F V E+VLPKFEV + P ++ + +N
Sbjct: 189 ISKTFQLSSHPILGDWSIQVQVNDQTYYQS-FQVSEYVLPKFEVTLQTPLYCSMNSKHLN 247
Query: 248 VSVCGLYTYGKPVPGHVTVSICRKYSDASDCHGEDSQAFCEKFSGQLNSHGCFYQQVKTK 307
++ YTYGKPV G VT++ + S + + K +G N F +
Sbjct: 248 GTITAKYTYGKPVKGDVTLT----FLPLSFWGKKKNITKTFKINGSANFS--FNDEEMKN 301
Query: 308 VFQLKR--KEYEMKLHTEAQIQEEGTVVE-LTGRQSSEITRTITK-----LSFVKVDSHF 359
V EY + L + ++ TV E +TG + T K + F +
Sbjct: 302 VMDSSNGLSEY-LDLSSPGPVEILTTVTESVTGISRNVSTNVFFKQHDYIIEFFDYTTVL 360
Query: 360 RQGIPFFGQVRLVDGKGVPIP------NKVIFI-RGNEANYYSNATTDEHGLVQFS-INT 411
+ + F V++ G + N VI + + N Y+S + + + IN
Sbjct: 361 KPSLNFTATVKVTRADGNQLTLEERRNNVVITVTQRNYTEYWSGSNSGNQKMEAVQKINY 420
Query: 412 TNVMGTSLTVRVNYKDRSPCYGYQ----WVSEEHEEAHHTAYLVFSPSKSFVHLEPMSHE 467
T + S T ++ + Q ++ + A H+ + SPSK+++ L+
Sbjct: 421 T--VPQSGTFKIEFPILEDSSELQLKAYFLGSKSSMAVHSLFK--SPSKTYIQLKTRDEN 476
Query: 468 LPCGHTQTVQAHYILNGGTLLGLKKLSFYYLIMAKGGIVRTGTHGLLVKQEDMKGHFSIS 527
+ G + +++G L K+LS Y+++++G +V G + S
Sbjct: 477 IKVGSPFEL----VVSGNKRL--KELS--YMVVSRGQLVAVGKQNSTM----------FS 518
Query: 528 IPVKSDIAPVARLLIYAVLPTGDVIGDSAKYDVENCLANKVDLSFSPSQSLPASHAHLRV 587
+ ++ P A +++Y + G++I D K V+ NK+ L +S ++ P+ LR+
Sbjct: 519 LTPENSWTPKACVIVYYIEDDGEIISDVLKIPVQLVFKNKIKLYWSKVKAEPSEKVSLRI 578
Query: 588 TAA-PQSVCALRAVDQSVLLMKPDAELSASSVYNLLPEKDLTGFPGPLNDQDDEDCINRH 646
+ P S+ + AVD+SV LM +++ +V + L + + G
Sbjct: 579 SVTQPDSIVGIVAVDKSVNLMNASNDITMENVVHELELYNTGYYLG-------------- 624
Query: 647 NVYINGITYTPVSSTNEKDMYSFLEDMGLKAFTNSKIRKPKMCPQLQQYEMHGPEGLRVG 706
+++N ++ ++ GL T++ + K + E
Sbjct: 625 -MFMNS--------------FAVFQECGLWVLTDANLTKDYIDGVYDNAE---------- 659
Query: 707 FYESDVMGRGHARLVHVEE------PHTETVRKYFPETWIWDLVVVNSAGVAEVGVTVPD 760
Y M +V + + PH VRK+FPETWIW + E VTVPD
Sbjct: 660 -YAERFMEENEGHIVDIHDFSLGSSPH---VRKHFPETWIWLDTNMGYRIYQEFEVTVPD 715
Query: 761 TITEWKAGAFCLSEDAGLGISST-ASLRAFQPFFVELTMPYSVIRGEAFTLKATVLNYLP 819
+IT W A F +SED GLG+++T L+AFQPFF+ L +PYSVIRGE F L+ T+ NYL
Sbjct: 716 SITSWVATGFVISEDLGLGLTTTPVELQAFQPFFIFLNLPYSVIRGEEFALEITIFNYLK 775
Query: 820 KCIRVSVQLEASPAFLAVPVEKE------QAPHCICANGRQTVSWAVTPKSLGNVNFTVS 873
V V +E S F + E Q + + TV + + P LG + TV+
Sbjct: 776 DATEVKVIIEKSDKFDILMTSNEINATGHQQTLLVPSEDGATVLFPIRPTHLGEIPITVT 835
Query: 874 AEALESQELCGTEVPSVPEHGRKDTVIKPLLVEPEGLEKETTFNSLLCPSGGEVS---EE 930
A + + D V + +LV+ EG+EK + + LL + + +
Sbjct: 836 ALSPTAS----------------DAVTQMILVKAEGIEKSYSQSILLDLTDNRLQSTLKT 879
Query: 931 LSLKLPPNVVEESARASVSVLGDILGSAMQNTQNLLQMPYGCGEQNMVLFAPNIYVLDYL 990
LS PPN V S R ++ +GD+LG ++ +L++MPYGCGEQNM+ FAPNIY+LDYL
Sbjct: 880 LSFSFPPNTVTGSERVQITAIGDVLGPSINGLASLIRMPYGCGEQNMINFAPNIYILDYL 939
Query: 991 NETQQLTPEIKSKAIGYLNTGYQRQLNYKHYDGSYSTFGERYGRNQGNTWLTAFVLKTFA 1050
+ +QLT +K KA+ ++ GYQR+L Y+ DGS+S FG G+TWL+AFVL+ F
Sbjct: 940 TKKKQLTDNLKEKALSFMRQGYQRELLYQREDGSFSAFGNY--DPSGSTWLSAFVLRCFL 997
Query: 1051 QARAYIFIDEAHITQALIWLSQRQKDNGCFRSSGSLLNNAIKGGVEDEVTLSAYITIALL 1110
+A YI ID+ + + WL QK NG F G ++++ ++GG + VTL+AYI +LL
Sbjct: 998 EADPYIDIDQNVLHRTYTWLKGHQKSNGEFWDPGRVIHSELQGGNKSPVTLTAYIVTSLL 1057
Query: 1111 EIPLTVTHPVVRNALFCLESAWKTAQEGDHGSHVYTKALLAYAFALAGNQDKRKEVLKSL 1170
+ V+ ++ LES + S YT AL+ YA + G+ K KE L L
Sbjct: 1058 GYRKYQPNIDVQESIHFLESEFSRGI-----SDNYTLALITYALSSVGS-PKAKEALNML 1111
Query: 1171 NEEAVKKDNSVHWERPQKPKAPVGHFYEPQAPSAEVEMTSYVLLAYLTAQPAPTSEDLTS 1230
A ++ W ++ + ++P+ S ++E+ +Y LL++ TSE +
Sbjct: 1112 TWRAEQEGGMQFW---VSSESKLSDSWQPR--SLDIEVAAYALLSHFL--QFQTSEGIP- 1163
Query: 1231 ATNIVKWITKQQNAQGGFSSTQDTVVALHALSKYGAATFT-RTGKAAQVTIQSSGTFSSK 1289
I++W+++Q+N+ GGF+STQDT VAL ALS++ A T RT VT SS + +
Sbjct: 1164 ---IMRWLSRQRNSLGGFASTQDTTVALKALSEFAALMNTERTNIQVTVTGPSSPSPLAV 1220
Query: 1290 FQVDNNNRLLLQQVSLPELPGEYSMKVTGEGCVYLQTSLKYNI-----------LPEKEE 1338
Q P ++ G G Q ++ YN+ + +E
Sbjct: 1221 VQ-----------------PTAVNISANGFGFAICQLNVVYNVKASGSSRRRRSIQNQEA 1263
Query: 1339 FPFALGVQTLPQTCDEPKAHTSFQISLSVSYTGSRSASNMAIVDVKMVSGFIPLKPTVKM 1398
F + V+ + H + S S G S MA+++V ++SGF+ + +
Sbjct: 1264 FDLDVAVKENKDDLN----HVDLNVCTSFSGPG---RSGMALMEVNLLSGFMVPSEAISL 1316
Query: 1399 LERSNHVSRTEVSSNHVLIYLDKVSNQTLSLFFTVLQDVPVRDLKPAIVKVYDYYETDEF 1458
S V + E + +YLD V+ + +++ V + + A V + DYYE
Sbjct: 1317 ---SETVKKVEYDHGKLNLYLDSVNETQFCVNIPAVRNFKVSNTQDASVSIVDYYEPRRQ 1373
Query: 1459 AIAEYNA 1465
A+ YN+
Sbjct: 1374 AVRSYNS 1380
>gi|227430303 CD109 antigen isoform 3 precursor [Homo sapiens]
Length = 1368
Score = 463 bits (1191), Expect = e-130
Identities = 387/1347 (28%), Positives = 630/1347 (46%), Gaps = 169/1347 (12%)
Query: 169 DPKGNRIAQWQSFQLEGGLKQFSFPLSSEPFQGSYKVVVQKKSGGRTEHPFTVEEFVLPK 228
DPK N I QW S Q + G+ +F LSS P G + + VQ + F V E+VLPK
Sbjct: 93 DPKSNLIQQWLSQQSDLGVISKTFQLSSHPILGDWSIQVQVNDQTYYQS-FQVSEYVLPK 151
Query: 229 FEVQVTVPKIITILEEEMNVSVCGLYTYGKPVPGHVTVSICRKYSDASDCHGEDSQAFCE 288
FEV + P ++ + +N ++ YTYGKPV G VT++ + S + +
Sbjct: 152 FEVTLQTPLYCSMNSKHLNGTITAKYTYGKPVKGDVTLT----FLPLSFWGKKKNITKTF 207
Query: 289 KFSGQLNSHGCFYQQVKTKVFQLKR--KEYEMKLHTEAQIQEEGTVVE-LTGRQSSEITR 345
K +G N F + V EY + L + ++ TV E +TG + T
Sbjct: 208 KINGSANFS--FNDEEMKNVMDSSNGLSEY-LDLSSPGPVEILTTVTESVTGISRNVSTN 264
Query: 346 TITK-----LSFVKVDSHFRQGIPFFGQVRLVDGKGVPIP------NKVIFI-RGNEANY 393
K + F + + + F V++ G + N VI + + N Y
Sbjct: 265 VFFKQHDYIIEFFDYTTVLKPSLNFTATVKVTRADGNQLTLEERRNNVVITVTQRNYTEY 324
Query: 394 YSNATTDEHGLVQFS-INTTNVMGTSLTVRVNYKDRSPCYGYQ----WVSEEHEEAHHTA 448
+S + + + IN T + S T ++ + Q ++ + A H+
Sbjct: 325 WSGSNSGNQKMEAVQKINYT--VPQSGTFKIEFPILEDSSELQLKAYFLGSKSSMAVHSL 382
Query: 449 YLVFSPSKSFVHLEPMSHELPCGHTQTVQAHYILNGGTLLGLKKLSFYYLIMAKGGIVRT 508
+ SPSK+++ L+ + G + +++G L K+LS Y+++++G +V
Sbjct: 383 FK--SPSKTYIQLKTRDENIKVGSPFEL----VVSGNKRL--KELS--YMVVSRGQLVAV 432
Query: 509 GTHGLLVKQEDMKGHFSISIPVKSDIAPVARLLIYAVLPTGDVIGDSAKYDVENCLANKV 568
G + S+ ++ P A +++Y + G++I D K V+ NK+
Sbjct: 433 GKQNSTM----------FSLTPENSWTPKACVIVYYIEDDGEIISDVLKIPVQLVFKNKI 482
Query: 569 DLSFSPSQSLPASHAHLRVTAA-PQSVCALRAVDQSVLLMKPDAELSASSVYNLLPEKDL 627
L +S ++ P+ LR++ P S+ + AVD+SV LM +++ +V + L +
Sbjct: 483 KLYWSKVKAEPSEKVSLRISVTQPDSIVGIVAVDKSVNLMNASNDITMENVVHELELYNT 542
Query: 628 TGFPGPLNDQDDEDCINRHNVYINGITYTPVSSTNEKDMYSFLEDMGLKAFTNSKIRKPK 687
+ G +++N ++ ++ GL T++ + K
Sbjct: 543 GYYLG---------------MFMNS--------------FAVFQECGLWVLTDANLTKDY 573
Query: 688 MCPQLQQYEMHGPEGLRVGFYESDVMGRGHARLVHVEE------PHTETVRKYFPETWIW 741
+ E Y M +V + + PH VRK+FPETWIW
Sbjct: 574 IDGVYDNAE-----------YAERFMEENEGHIVDIHDFSLGSSPH---VRKHFPETWIW 619
Query: 742 DLVVVNSAGVAEVGVTVPDTITEWKAGAFCLSEDAGLGISST-ASLRAFQPFFVELTMPY 800
+ E VTVPD+IT W A F +SED GLG+++T L+AFQPFF+ L +PY
Sbjct: 620 LDTNMGYRIYQEFEVTVPDSITSWVATGFVISEDLGLGLTTTPVELQAFQPFFIFLNLPY 679
Query: 801 SVIRGEAFTLKATVLNYLPKCIRVSVQLEASPAFLAVPVEKE------QAPHCICANGRQ 854
SVIRGE F L+ T+ NYL V V +E S F + E Q + +
Sbjct: 680 SVIRGEEFALEITIFNYLKDATEVKVIIEKSDKFDILMTSNEINATGHQQTLLVPSEDGA 739
Query: 855 TVSWAVTPKSLGNVNFTVSAEALESQELCGTEVPSVPEHGRKDTVIKPLLVEPEGLEKET 914
TV + + P LG + TV+A + + D V + +LV+ EG+EK
Sbjct: 740 TVLFPIRPTHLGEIPITVTALSPTAS----------------DAVTQMILVKAEGIEKSY 783
Query: 915 TFNSLLCPSGGEVS---EELSLKLPPNVVEESARASVSVLGDILGSAMQNTQNLLQMPYG 971
+ + LL + + + LS PPN V S R ++ +GD+LG ++ +L++MPYG
Sbjct: 784 SQSILLDLTDNRLQSTLKTLSFSFPPNTVTGSERVQITAIGDVLGPSINGLASLIRMPYG 843
Query: 972 CGEQNMVLFAPNIYVLDYLNETQQLTPEIKSKAIGYLNTGYQRQLNYKHYDGSYSTFGER 1031
CGEQNM+ FAPNIY+LDYL + +QLT +K KA+ ++ GYQR+L Y+ DGS+S FG
Sbjct: 844 CGEQNMINFAPNIYILDYLTKKKQLTDNLKEKALSFMRQGYQRELLYQREDGSFSAFGNY 903
Query: 1032 YGRNQGNTWLTAFVLKTFAQARAYIFIDEAHITQALIWLSQRQKDNGCFRSSGSLLNNAI 1091
G+TWL+AFVL+ F +A YI ID+ + + WL QK NG F G ++++ +
Sbjct: 904 --DPSGSTWLSAFVLRCFLEADPYIDIDQNVLHRTYTWLKGHQKSNGEFWDPGRVIHSEL 961
Query: 1092 KGGVEDEVTLSAYITIALLEIPLTVTHPVVRNALFCLESAWKTAQEGDHGSHVYTKALLA 1151
+GG + VTL+AYI +LL + V+ ++ LES + S YT AL+
Sbjct: 962 QGGNKSPVTLTAYIVTSLLGYRKYQPNIDVQESIHFLESEFSRGI-----SDNYTLALIT 1016
Query: 1152 YAFALAGNQDKRKEVLKSLNEEAVKKDNSVHWERPQKPKAPVGHFYEPQAPSAEVEMTSY 1211
YA + G+ K KE L L A ++ W ++ + ++P+ S ++E+ +Y
Sbjct: 1017 YALSSVGS-PKAKEALNMLTWRAEQEGGMQFW---VSSESKLSDSWQPR--SLDIEVAAY 1070
Query: 1212 VLLAYLTAQPAPTSEDLTSATNIVKWITKQQNAQGGFSSTQDTVVALHALSKYGAATFT- 1270
LL++ TSE + I++W+++Q+N+ GGF+STQDT VAL ALS++ A T
Sbjct: 1071 ALLSHFL--QFQTSEGIP----IMRWLSRQRNSLGGFASTQDTTVALKALSEFAALMNTE 1124
Query: 1271 RTGKAAQVTIQSSGTFSSKFQVDNNNRLLLQQVSLPEL-PGEYSMKVTGEGCVYLQTSLK 1329
RT VT SS + KF +D +NRLLLQ L + P ++ G G Q ++
Sbjct: 1125 RTNIQVTVTGPSSPS-PVKFLIDTHNRLLLQTAELAVVQPTAVNISANGFGFAICQLNVV 1183
Query: 1330 YNI-----------LPEKEEFPFALGVQTLPQTCDEPKAHTSFQISLSVSYTGSRSASNM 1378
YN+ + +E F + V+ + H + S S G S M
Sbjct: 1184 YNVKASGSSRRRRSIQNQEAFDLDVAVKENKDDLN----HVDLNVCTSFSGPG---RSGM 1236
Query: 1379 AIVDVKMVSGFIPLKPTVKMLERSNHVSRTEVSSNHVLIYLDKVSNQTLSLFFTVLQDVP 1438
A+++V ++SGF+ + + S V + E + +YLD V+ + +++
Sbjct: 1237 ALMEVNLLSGFMVPSEAISL---SETVKKVEYDHGKLNLYLDSVNETQFCVNIPAVRNFK 1293
Query: 1439 VRDLKPAIVKVYDYYETDEFAIAEYNA 1465
V + + A V + DYYE A+ YN+
Sbjct: 1294 VSNTQDASVSIVDYYEPRRQAVRSYNS 1320
>gi|239750255 PREDICTED: similar to ovostatin-2 [Homo sapiens]
Length = 750
Score = 452 bits (1164), Expect = e-127
Identities = 253/644 (39%), Positives = 373/644 (57%), Gaps = 22/644 (3%)
Query: 381 NKVIFIRGNEANYYSNATTDEHGLVQFSINTTNVMGTSLTVRVNYKDRSPCYGYQWVSEE 440
NK++ + N+ + N TTDE+G QFSI+T+++ ++ Y CY W++ +
Sbjct: 3 NKLLQLELND-EFIGNYTTDENGEAQFSIDTSDIFDPEFNLKATYVRPESCYLPSWLTPQ 61
Query: 441 HEEAHHTAYLVFSPSKSFVHLEPMSHELPCGHTQTVQAHYILNGGTLLGLKKLSFYYLIM 500
+ +AH +S + SF+ + P +L C H + V HY LN + F+YL
Sbjct: 62 YLDAHFLVSRFYSRTNSFLKIVPEPKQLECNHQKVVTVHYSLNSEAYEDDSNVKFFYLCT 121
Query: 501 AKGGIVRTGTHGLLVKQEDMKGHFSISIPVKSDIAPVARLLIYAVLPTGDVIGDSAKYDV 560
+ G + + G+FS + + +D+AP A L +Y + P+G+++ DS ++ V
Sbjct: 122 SDSGNFQHRISSSPIYTA-WNGNFSFPLSISADLAPAAVLFVYTLHPSGEIVADSVRFQV 180
Query: 561 ENCLANKVDLSFSPSQSLPASHAHLRVTAAPQSVCALRAVDQSVLLMKPDAELSASSVYN 620
+ C +KV++ FS Q LP S+A L + AAP CAL AVD +VLL+K + +LSA SVYN
Sbjct: 181 DKCFKHKVNIKFSNEQGLPGSNASLYLQAAPVLFCALGAVDGNVLLLKSEQQLSAESVYN 240
Query: 621 LLPEKDLTGF---PGPLNDQDDEDCINRHNVYINGITYTPVSSTNEKDMYSFLEDMGLKA 677
++P + G+ L+D ++ CI + +++ NG+ YTPVS+ + D+Y+ + +MGLK
Sbjct: 241 MVPSIEPYGYFYHGLNLDDGKEDPCIPQRDMFYNGLYYTPVSNYGDGDIYNIVRNMGLKV 300
Query: 678 FTNSKIRKPKMC----------PQLQQYEMHGP-EGLRVGFYESDVMGRGHARLVHVEEP 726
FTN RKP++C P + E +GP + S + G +VE+
Sbjct: 301 FTNLHYRKPEVCVMERRLPLPKPLYLETENYGPMHSVPSRIASSGIRGENAD---YVEQA 357
Query: 727 HTETVRKYFPETWIWDLVVVNSAGVAEVGVTVPDTITEWKAGAFCLSEDAGLGISSTASL 786
+TVR FPETW+WDLV V+S+G A + +PDTIT+W+A FC++ D G GISST +L
Sbjct: 358 IIQTVRTNFPETWMWDLVSVDSSGSANLSFLIPDTITQWEASGFCVNGDVGFGISSTTTL 417
Query: 787 RAFQPFFVELTMPYSVIRGEAFTLKATVLNYLPKCIRVSVQLEASPAFLA-VPVEKEQAP 845
QPFF+E+ P+SV++ E F L +YL C+ +SVQ+E S + A + K
Sbjct: 418 EVSQPFFIEIASPFSVVQNEQFDLIVNAFSYLNTCVEISVQVEESQNYEANINTWKINGS 477
Query: 846 HCICANGRQTVSWAVTPKSLGNVNFTVSAEALESQELCGTEVPSVPEHGRKDTVIKPLLV 905
I A GR+T W + PK LG VN TV AE+ +S C E + KDTV+K LV
Sbjct: 478 EVIQAGGRKTNIWTIIPKKLGKVNITVVAESKQS-SACPNEGMEQQKLNWKDTVVKSFLV 536
Query: 906 EPEGLEKETTFNSLLCPSGGEVSEELSLKLPPNVVEESARASVSVLGDILGSAMQNTQNL 965
EPEG+EKE T + L+C G + S++ L LP +VVE SAR +V+GDILG AMQN +
Sbjct: 537 EPEGIEKERTQSFLICTEGAKASKQGVLDLPNDVVEGSARGFFTVVGDILGLAMQNLV-V 595
Query: 966 LQMPYGCGEQNMVLFAPNIYVLDYLNETQQLTPEIKSKAIGYLN 1009
LQMPYG GEQN L A + YVLDYL T+QLT E++SKA L+
Sbjct: 596 LQMPYGGGEQNAALLASDTYVLDYLKSTEQLTEEVQSKAFFLLS 639
>gi|118600977 C3 and PZP-like, alpha-2-macroglobulin domain containing
8 [Homo sapiens]
Length = 1932
Score = 313 bits (803), Expect = 6e-85
Identities = 207/589 (35%), Positives = 308/589 (52%), Gaps = 62/589 (10%)
Query: 928 SEELSLKLPPNVVEESARASVSVLGDILGSAMQNTQNLLQMPYGCGEQNMVLFAPNIYVL 987
SE +L +P + S RA+ S++GD++G + + NLL++P+GCGEQNM+ FAPN++VL
Sbjct: 1147 SEAFTLGVPHGAIPGSERATASIIGDVMGPTLNHLNNLLRLPFGCGEQNMIHFAPNVFVL 1206
Query: 988 DYLNETQQLTPEIKSKAIGYLNTGYQRQLNYKHYDGSYSTFGERYGRNQGNTWLTAFVLK 1047
YL +TQQL+PE++ + YL GYQRQL YK DGSYS FGER G+ WLTAFVLK
Sbjct: 1207 KYLQKTQQLSPEVERETTDYLVQGYQRQLTYKRQDGSYSAFGERDA--SGSMWLTAFVLK 1264
Query: 1048 TFAQARAYIFIDEAHITQALIWLSQRQKDNGCFRSSGSLLNNAIKGGVEDEVTLSAYITI 1107
+FAQAR++IF+D + A W+ Q+Q+ +G F + G +LN I+GG+ V L+AY+ +
Sbjct: 1265 SFAQARSFIFVDPRELAAAKSWIIQQQQADGSFLAVGRVLNKDIQGGIHGTVPLTAYVVV 1324
Query: 1108 ALLEIPLTVTHP--VVRNALFCLESAWKTAQEGDHGSHVYTKALLAYAFALAGNQDKRKE 1165
ALLE A LESA A + Y+ AL YA L E
Sbjct: 1325 ALLETGTASEEERGSTDKARHFLESAAPLAMD------PYSCALTTYALTLL-RSPAAPE 1377
Query: 1166 VLKSLNEEAVKKDNSVHWERPQKPKAPVGHF------YEPQAPSAEVEMTSYVLLAYLTA 1219
L+ L A+ +D HW G F SAEVEMT+Y LL Y
Sbjct: 1378 ALRKLRSLAIMRDGVTHWSLSNSWDVDKGTFLSFSDRVSQSVVSAEVEMTAYALLTYTLL 1437
Query: 1220 QPAPTSEDLTSATNIVKWITKQQNAQGGFSSTQDTVVALHALSKYGAATFTRTGKAAQVT 1279
D+ +A +VKW+++Q+NA GGFSSTQDT VAL AL++Y ++ G V+
Sbjct: 1438 ------GDVAAALPVVKWLSQQRNALGGFSSTQDTCVALQALAEYAILSYA-GGINLTVS 1490
Query: 1280 IQSSG-TFSSKFQVDNNNRLLLQQVSLPELPGEYSMKVTGEGCVYLQTSLKYNILPE--- 1335
+ S+ + F++ N+ +LQ ++P LP + G+GC +Q + YN+ P+
Sbjct: 1491 LASTNLDYQETFELHRTNQKVLQTAAIPSLPTGLFVSAKGDGCCLMQIDVTYNV-PDPVA 1549
Query: 1336 KEEFPFALGVQT----------------------LPQTCDEPKA---HTSFQISLSVSYT 1370
K F + +Q P D+P A H +++ L V
Sbjct: 1550 KPAFQLLVSLQEPEAQGRPPPMPASAAEGSRGDWPPADDDDPAADQHHQEYKVMLEVCTR 1609
Query: 1371 GSRS-ASNMAIVDVKMVSGFIPLKPTVKMLERSNH--VSRTEVSSNHVLIYLDKVSNQTL 1427
+ +SNMA+++V ++SGF +++ L H + R EV+ VL Y D++ ++ L
Sbjct: 1610 WLHAGSSNMAVLEVPLLSGFRADIESLEQLLLDKHMGMKRYEVAGRRVLFYFDEIPSRCL 1669
Query: 1428 S-LFFTVLQDVPVRDLKPAIVKVYDYYETDEFAIAEYN----APCSKDL 1471
+ + F L++ V V VYDYYE A YN +P +++L
Sbjct: 1670 TCVRFRALRECVVGRTSALPVSVYDYYEPAFEATRFYNVSTHSPLAREL 1718
Score = 247 bits (631), Expect = 5e-65
Identities = 243/988 (24%), Positives = 416/988 (42%), Gaps = 114/988 (11%)
Query: 6 LLHPSLVLLLLVLLPTDASVSGKPQ---YMVLVPSLLHTETTEKGCVLLSYLNETVTVSA 62
LL P L LLLL+L D + +PQ Y++ PS+ E V + VTV A
Sbjct: 52 LLWPLLPLLLLLLSARDGVRAAQPQAPGYLIAAPSVFRAGVEEVISVTIFNSPREVTVQA 111
Query: 63 SL----ESVRGNRSLFTDLEAENDVLHCVAFAVPKSSSNEEVMFLTVQVKGPTQE----F 114
L E V ++ D + VP + + L V +G E F
Sbjct: 112 QLVAQGEPVVQSQGAILDKGT-------IKLKVPTGLRGQAL--LKVWGRGWQAEEGPLF 162
Query: 115 KKRTTVMVKNEDSLVFVQTDKSIYKPGQTVKFRVVSMDENFHPLNELIPLVYIQDPKGNR 174
+T+V V + VF+QTDK +Y+P V + ++ N P+NE + YI DP+G+R
Sbjct: 163 HNQTSVTVDGRGASVFIQTDKPVYRPQHRVLISIFTVSPNLRPVNEKLE-AYILDPRGSR 221
Query: 175 IAQWQSFQ-LEGGLKQFSFPLSSEPFQGSYKVVVQKKSGGRTEHPFTVEEFVLPKFEVQV 233
+ +W+ + G+ SFPLS +P G + + V+ + G F V+++VLPKFE+ +
Sbjct: 222 MIEWRHLKPFCCGITNMSFPLSDQPVLGEWFIFVEMQ-GHAYNKSFEVQKYVLPKFELLI 280
Query: 234 TVPKIITILEEEMNVSVCGLYTYGKPVPGHVTVSICRKYSDASDCHGEDSQAFCEKFSGQ 293
P+ I L+ +V YT+GKPV G + +++ K G
Sbjct: 281 DPPRYIQDLDACETGTVRARYTFGKPVAGALMINMTVNGVGYYSHEVGRPVLRTTKILGS 340
Query: 294 LNSHGCFYQQVKTKVFQLKRKEYEMKLHTEAQIQEEGTVVELTGRQSSEITRTITKLSFV 353
+ C + V + + ++ A + ++ S+ + R + + +
Sbjct: 341 RDFDICVRDMIPADV----PEHFRGRVSIWAMVTSVDGSQQVAFDDSTPVQRQLVDIRYS 396
Query: 354 K-VDSHFRQGIPFFGQVRLVDGKGVPIPNKVIFIRGN---EANYYSNATTDEHGLVQFSI 409
K F+ G+ + G+V L G P + I+ + N Y++ + GLV F I
Sbjct: 397 KDTRKQFKPGLAYVGKVELSYPDGSPAEGVTVQIKAELTPKDNIYTSEVVSQRGLVGFEI 456
Query: 410 NT--TNVMGTSLTVRVNYKDRSPCYGYQWVSEEHEEAHHTAYLVFSPSKSFVHLEPMSHE 467
+ T+ L +V + P V ++ ++ + +SPS+ ++ L+P SH
Sbjct: 457 PSIPTSAQHVWLETKVMALNGKP------VGAQYLPSYLSLGSWYSPSQCYLQLQPPSHP 510
Query: 468 LPCGHTQTVQAHYILNGGTLLGLKKLSFYYLIMAKGGIVRTGTHGLLVKQEDMK------ 521
L G +A++ + + YY + A+G IV +G Q+ K
Sbjct: 511 LQVGE----EAYFSVKSTCPC---NFTLYYEVAARGNIVLSGQQPAHTTQQRSKRAAPAL 563
Query: 522 ------GHF------------------SISIPVKSDIAPVARLLIYAVLPTGDVIGDSAK 557
H S+ + V + P+ RLL++ V G+ + DS +
Sbjct: 564 EKPIRLTHLSETEPPPAPEAEVDVCVTSLHLAVTPSMVPLGRLLVFYVRENGEGVADSLQ 623
Query: 558 YDVENCLANKVDLSFSPSQSLPASHAHLRVTAAPQSVCALRAVDQSVLLMKPDAELSASS 617
+ VE N+V +++S +++ P LR+ AA S + AVD+SV L++ L+ +
Sbjct: 624 FAVETFFENQVSVTYSANETQPGEVVDLRIRAARGSCVCVAAVDKSVYLLRSGFRLTPAQ 683
Query: 618 VYNLLPEKDLTGFPGPLNDQDDEDCINRHNVYINGITYTPVSSTNEKDMYSFLEDMGLKA 677
V+ L + D++ D ++R + + +++ + F G+
Sbjct: 684 VFQELEDYDVS----------DSFGVSRED---GPFWWAGLTAQRRRRSSVFPWPWGITK 730
Query: 678 FTNSKIRKPKMCPQLQQYEM-HGPEGLRVGFYESDVM-------GRGHARLVHVEEPHTE 729
+ + + + + H +G G Y + + G A P TE
Sbjct: 731 DSGFAFTETGLVVMTDRVSLNHRQDG---GLYTDEAVPAFQPHTGSLVAVAPSRHPPRTE 787
Query: 730 -TVRKYFPETWIWD-LVVVNSAGVAEVGVTVPDTITEWKAGAFCLSEDAGLGISSTASLR 787
R +FPETWIW L + + +G + V VPD+IT W A LS GLGI+ + L+
Sbjct: 788 KRKRTFFPETWIWHCLNISDPSGEGTLSVKVPDSITSWVGEAVALSTSQGLGIAEPSLLK 847
Query: 788 AFQPFFVELTMPYSVIRGEAFTLKATVLNYLPKCIRVSVQLEASPA--FLAVPVEKEQAP 845
F+PFFV+ +P +IRGE + +V NY+ C V ++L F+ P ++
Sbjct: 848 TFKPFFVDFMLPALIIRGEQVKIPLSVYNYMGTCAEVYMKLSVPKGIQFVGHPGKRHVTK 907
Query: 846 HCICANGRQTVSWAVTPKS-LGNVNFTVSAEALESQELC----GTEVPSVPEHGRK---- 896
A G W V S LG N T A A C ++ P R+
Sbjct: 908 KMCVAPGEAEPIWVVLSFSDLGLNNITAKALAYGDTNCCRDGRSSKHPEENHADRRVPIG 967
Query: 897 -DTVIKPLLVEPEGLEKETTFNSLLCPS 923
D V + ++VE EG+ + T+++ CPS
Sbjct: 968 VDHVRRSVMVEAEGVPRAYTYSAFFCPS 995
>gi|178557739 complement component 4B preproprotein [Homo sapiens]
Length = 1744
Score = 299 bits (766), Expect = 1e-80
Identities = 386/1505 (25%), Positives = 613/1505 (40%), Gaps = 229/1505 (15%)
Query: 129 VFVQTDKSIYKPGQTVKFRVVSMDENFHPLNELIPLVYIQDPKGNRIAQWQSFQLEGGLK 188
+F+QTD+ IY PGQ V++RV ++D+ P + I V +++ G R+ + + + +
Sbjct: 141 LFLQTDQPIYNPGQRVRYRVFALDQKMRPSTDTIT-VMVENSHGLRVRKKEVYMPSSIFQ 199
Query: 189 Q-FSFPLSSEPFQGSYKVVVQKKSG--GRTEHPFTVEEFVLPKFEVQVTV--PKIITILE 243
F P SEP G++K+ + G + F V+++VLP FEV++T P I+T+
Sbjct: 200 DDFVIPDISEP--GTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKITPGKPYILTVPG 257
Query: 244 --EEMNVSVCGLYTYGKPVPG--HVTVSICRKYSDASDCHGEDSQAFCEKFSGQLNSHGC 299
+EM + + Y YGKPV G +V + + + G +SQ ++
Sbjct: 258 HLDEMQLDIQARYIYGKPVQGVAYVRFGLLDEDGKKTFFRGLESQTKLVNGQSHISLSKA 317
Query: 300 FYQQVKTKVFQLKRKEYEMKLHTEAQIQEE-GTVVELTGRQSSEITRTITKLSFVKVDSH 358
+Q K+ ++L+ A I E G +E S + L K H
Sbjct: 318 EFQDALEKLNMGITDLQGLRLYVAAAIIESPGGEMEEAELTSWYFVSSPFSLDLSKTKRH 377
Query: 359 FRQGIPFFGQVRLVDGKGVP---IPNKVIFIRGNEANYYS----NATTDEHGLVQFSINT 411
G PF Q + + G P IP KV + + TD G V I
Sbjct: 378 LVPGAPFLLQALVREMSGSPASGIPVKVSATVSSPGSVPEVQDIQQNTDGSGQVSIPIII 437
Query: 412 TNVMGTSLTVRVNYKDRSPCYGYQWVSEEHEEAHHTAYLVFSPSKSFVHLE-PMSHELPC 470
+ + L + V+ P A T S F+ +E P S
Sbjct: 438 PQTI-SELQLSVSAGSPHPAI-----------ARLTVAAPPSGGPGFLSIERPDSRPPRV 485
Query: 471 GHTQTVQAHYILNGGTLLGLKKLSFYYLIMAKGGIVRTGTHGLLVKQEDMKGHFSISIPV 530
G T + + +G T +YY+I+++G IV + +E + S+S+ V
Sbjct: 486 GDTLNLNLRAVGSGATFS-----HYYYMILSRGQIV-------FMNREPKRTLTSVSVFV 533
Query: 531 KSDIAPVARLLIYAVLPTGD-VIGDSAKYDVE-NCLANKVDLSFSPS-QSLPASHAHLRV 587
+AP A GD + +S + DV+ K++LS + Q L +
Sbjct: 534 DHHLAP--SFYFVAFYYHGDHPVANSLRVDVQAGACEGKLELSVDGAKQYRNGESVKLHL 591
Query: 588 TAAPQSVCALRAVDQSVLLM--KPDAELSASSVYNLLPEKDLTGFPGPLND--------- 636
++ AL A+D ++ K L+ V+ + DL PG +
Sbjct: 592 ETDSLALVALGALDTALYAAGSKSHKPLNMGKVFEAMNSYDLGCGPGGGDSALQVFQAAG 651
Query: 637 ----QDDEDCINRHNVYINGITYTPVSSTNEKDMYSFL----EDMGLKAFTNSK------ 682
D+ ++R ++ +T +K +F E +G A +K
Sbjct: 652 LAFSDGDQWTLSRKR-----LSCPKEKTTRKKRNVNFQKAINEKLGQYASPTAKRCCQDG 706
Query: 683 -IRKPKM--CPQ----LQQYEMHGP--------EGLRVGFYESDVMGRGHARLVHVEEPH 727
R P M C Q +QQ + P E LR + G A + EE
Sbjct: 707 VTRLPMMRSCEQRAARVQQPDCREPFLSCCQFAESLRKKSRDKGQAGLQRALEILQEEDL 766
Query: 728 TET----VRKYFPETWIWDLVVVNSAGVAEVGVTVPDTITEWKAGAFCLSEDAGLGISST 783
+ VR +FPE W+W + V+ + + + +PD++T W+ LS+ GL +++
Sbjct: 767 IDEDDIPVRSFFPENWLWRVETVDRFQI--LTLWLPDSLTTWEIHGLSLSKTKGLCVATP 824
Query: 784 ASLRAFQPFFVELTMPYSVIRGEAFTLKATVLNYLPKCIRVSVQLEASPAFLAVPVEKEQ 843
LR F+ F + L +P SV R E L+ + NYL K + VSV + PVE
Sbjct: 825 VQLRVFREFHLHLRLPMSVRRFEQLELRPVLYNYLDKNLTVSVHVS--------PVEGL- 875
Query: 844 APHCICANGRQTVSWAVTPKSLGNVNFTVSAEALESQELCGTEVPSVPEHGRKDTVIKPL 903
C+ G V S V F+V A + L S E D V K L
Sbjct: 876 ---CLAGGGGLAQQVLVPAGSARPVAFSVVPTAATAVSLKVVARGSF-EFPVGDAVSKVL 931
Query: 904 LVEPEG-LEKETTFNSLLCPSGGEVSEELSLKLPPNVVEES-----ARASVSVLGDILGS 957
+E EG + +E L + E+ PN++ + R + S D LGS
Sbjct: 932 QIEKEGAIHREELVYELNPLDHRGRTLEIPGNSDPNMIPDGDFNSYVRVTASDPLDTLGS 991
Query: 958 ----AMQNTQNLLQMPYGCGEQNMVLFAPNIYVLDYLNETQQ---LTPEIKSKAIGYLNT 1010
+ +LL++P GCGEQ M+ AP + YL++T+Q L PE K A+ +
Sbjct: 992 EGALSPGGVASLLRLPRGCGEQTMIYLAPTLAASRYLDKTEQWSTLPPETKDHAVDLIQK 1051
Query: 1011 GYQRQLNYKHYDGSYSTFGERYGRNQGNTWLTAFVLKTFAQARAYIFIDEAHITQALIWL 1070
GY R ++ DGSY+ + R +TWLTAFVLK + A+ + + + WL
Sbjct: 1052 GYMRIQQFRKADGSYAAWLSR----GSSTWLTAFVLKVLSLAQEQVGGSPEKLQETSNWL 1107
Query: 1071 SQRQKDNGCFRSSGSLLNNAIKGGV---EDEVTLSAYITIALLEIPLTV-----THPVVR 1122
+Q+ +G F+ +++ +++GG+ ++ V L+A++TIAL L V P+ +
Sbjct: 1108 LSQQQADGSFQDLSPVIHRSMQGGLVGNDETVALTAFVTIALHH-GLAVFQDEGAEPLKQ 1166
Query: 1123 NALFCLESA----WKTAQEGDHGSHVYTKALLAYAFALA-GNQDKRKEVLKSLNEEAVKK 1177
+ A + A G G+H A+ AYA L D R +L A +
Sbjct: 1167 RVEASISKASSFLGEKASAGLLGAHA--AAITAYALTLTKAPADLRGVAHNNLMAMAQET 1224
Query: 1178 DNSVHW--------------ERPQKPKAPVGHFYEPQAPSAEVEMTSYVLLAYLTAQPAP 1223
++++W P+ P P+ PQAP+ +E T+Y LL L +
Sbjct: 1225 GDNLYWGSVTGSQSNAVSPTPAPRNPSDPM-----PQAPALWIETTAYALLHLLLHEGKA 1279
Query: 1224 TSEDLTSATNIVKWITKQQNAQGGFSSTQDTVVALHALSKYGAATFTRTGKAAQVTIQSS 1283
D +A W+T+Q + QGGF STQDTV+AL ALS Y A+ T + VT+ S+
Sbjct: 1280 EMADQAAA-----WLTRQGSFQGGFRSTQDTVIALDALSAYWIASHTTEERGLNVTLSST 1334
Query: 1284 GTFSSK---FQVDNNNRLLLQQVSLPELPGEYSMKVTGEGCVYLQTSLKYNILPEKEEFP 1340
G K Q++N L++ L + ++KV G L+ YN+L K
Sbjct: 1335 GRNGFKSHALQLNNRQIRGLEEELQFSLGSKINVKVGGNSKGTLKVLRTYNVLDMKNTTC 1394
Query: 1341 FALGVQT-----------------------LPQTCDEPKAH----TSFQI---------- 1363
L ++ LP D+P A T Q+
Sbjct: 1395 QDLQIEVTVKGHVEYTMEANEDYEDYEYDELPAK-DDPDAPLQPVTPLQLFEGRRNRRRR 1453
Query: 1364 ---------SLSVSYT------GSRSASNMAIVDVKMVSGFIPLKPTVKMLE--RSNHVS 1406
V YT G S MAI DV ++SGF L+ ++ L +VS
Sbjct: 1454 EAPKVVEEQESRVHYTVCIWRNGKVGLSGMAIADVTLLSGFHALRADLEKLTSLSDRYVS 1513
Query: 1407 RTEVSSNHVLIYLDKVSNQTLSLFFTVLQDVPVRDLKPAIVKVYDYYETDEFAIAEYNAP 1466
E HVL+Y D V + F +Q+VPV ++PA +YDYY + Y AP
Sbjct: 1514 HFETEGPHVLLYFDSVPTSRECVGFEAVQEVPVGLVQPASATLYDYYNPERRCSVFYGAP 1573
Query: 1467 CSKDL 1471
L
Sbjct: 1574 SKSRL 1578
>gi|67190748 complement component 4A preproprotein [Homo sapiens]
Length = 1744
Score = 298 bits (763), Expect = 3e-80
Identities = 382/1505 (25%), Positives = 611/1505 (40%), Gaps = 229/1505 (15%)
Query: 129 VFVQTDKSIYKPGQTVKFRVVSMDENFHPLNELIPLVYIQDPKGNRIAQWQSFQLEGGLK 188
+F+QTD+ IY PGQ V++RV ++D+ P + I V +++ G R+ + + + +
Sbjct: 141 LFLQTDQPIYNPGQRVRYRVFALDQKMRPSTDTIT-VMVENSHGLRVRKKEVYMPSSIFQ 199
Query: 189 Q-FSFPLSSEPFQGSYKVVVQKKSG--GRTEHPFTVEEFVLPKFEVQVTV--PKIITILE 243
F P SEP G++K+ + G + F V+++VLP FEV++T P I+T+
Sbjct: 200 DDFVIPDISEP--GTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKITPGKPYILTVPG 257
Query: 244 --EEMNVSVCGLYTYGKPVPG--HVTVSICRKYSDASDCHGEDSQAFCEKFSGQLNSHGC 299
+EM + + Y YGKPV G +V + + + G +SQ ++
Sbjct: 258 HLDEMQLDIQARYIYGKPVQGVAYVRFGLLDEDGKKTFFRGLESQTKLVNGQSHISLSKA 317
Query: 300 FYQQVKTKVFQLKRKEYEMKLHTEAQIQEE-GTVVELTGRQSSEITRTITKLSFVKVDSH 358
+Q K+ ++L+ A I E G +E S + L K H
Sbjct: 318 EFQDALEKLNMGITDLQGLRLYVAAAIIESPGGEMEEAELTSWYFVSSPFSLDLSKTKRH 377
Query: 359 FRQGIPFFGQVRLVDGKGVP---IPNKVIFIRGNEANYYS----NATTDEHGLVQFSINT 411
G PF Q + + G P IP KV + + TD G V I
Sbjct: 378 LVPGAPFLLQALVREMSGSPASGIPVKVSATVSSPGSVPEVQDIQQNTDGSGQVSIPIII 437
Query: 412 TNVMGTSLTVRVNYKDRSPCYGYQWVSEEHEEAHHTAYLVFSPSKSFVHLE-PMSHELPC 470
+ + L + V+ P A T S F+ +E P S
Sbjct: 438 PQTI-SELQLSVSAGSPHPAI-----------ARLTVAAPPSGGPGFLSIERPDSRPPRV 485
Query: 471 GHTQTVQAHYILNGGTLLGLKKLSFYYLIMAKGGIVRTGTHGLLVKQEDMKGHFSISIPV 530
G T + + +G T +YY+I+++G IV + +E + S+S+ V
Sbjct: 486 GDTLNLNLRAVGSGATFS-----HYYYMILSRGQIV-------FMNREPKRTLTSVSVFV 533
Query: 531 KSDIAPVARLLIYAVLPTGD-VIGDSAKYDVE-NCLANKVDLSFSPS-QSLPASHAHLRV 587
+AP A GD + +S + DV+ K++LS + Q L +
Sbjct: 534 DHHLAP--SFYFVAFYYHGDHPVANSLRVDVQAGACEGKLELSVDGAKQYRNGESVKLHL 591
Query: 588 TAAPQSVCALRAVDQSVLLM--KPDAELSASSVYNLLPEKDLTGFPGPLND--------- 636
++ AL A+D ++ K L+ V+ + DL PG +
Sbjct: 592 ETDSLALVALGALDTALYAAGSKSHKPLNMGKVFEAMNSYDLGCGPGGGDSALQVFQAAG 651
Query: 637 ----QDDEDCINRHNVYINGITYTPVSSTNEKDMYSFL----EDMGLKAFTNSK------ 682
D+ ++R ++ +T +K +F E +G A +K
Sbjct: 652 LAFSDGDQWTLSRKR-----LSCPKEKTTRKKRNVNFQKAINEKLGQYASPTAKRCCQDG 706
Query: 683 -IRKPKM--CPQ----LQQYEMHGP--------EGLRVGFYESDVMGRGHARLVHVEEPH 727
R P M C Q +QQ + P E LR + G A + EE
Sbjct: 707 VTRLPMMRSCEQRAARVQQPDCREPFLSCCQFAESLRKKSRDKGQAGLQRALEILQEEDL 766
Query: 728 TET----VRKYFPETWIWDLVVVNSAGVAEVGVTVPDTITEWKAGAFCLSEDAGLGISST 783
+ VR +FPE W+W + V+ + + + +PD++T W+ LS+ GL +++
Sbjct: 767 IDEDDIPVRSFFPENWLWRVETVDRFQI--LTLWLPDSLTTWEIHGLSLSKTKGLCVATP 824
Query: 784 ASLRAFQPFFVELTMPYSVIRGEAFTLKATVLNYLPKCIRVSVQLEASPAFLAVPVEKEQ 843
LR F+ F + L +P SV R E L+ + NYL K + VSV +
Sbjct: 825 VQLRVFREFHLHLRLPMSVRRFEQLELRPVLYNYLDKNLTVSVHVSPVEGLCLAGGGGLA 884
Query: 844 APHCICANGRQTVSWAVTPKSLGNVNFTVSAEALESQELCGTEVPSVPEHGRKDTVIKPL 903
+ A + V+++V P + V+ V A E P D V K L
Sbjct: 885 QQVLVPAGSARPVAFSVVPTAAAAVSLKVVARG-------SFEFPV------GDAVSKVL 931
Query: 904 LVEPEG-LEKETTFNSLLCPSGGEVSEELSLKLPPNVVEES-----ARASVSVLGDILGS 957
+E EG + +E L + E+ PN++ + R + S D LGS
Sbjct: 932 QIEKEGAIHREELVYELNPLDHRGRTLEIPGNSDPNMIPDGDFNSYVRVTASDPLDTLGS 991
Query: 958 ----AMQNTQNLLQMPYGCGEQNMVLFAPNIYVLDYLNETQQ---LTPEIKSKAIGYLNT 1010
+ +LL++P GCGEQ M+ AP + YL++T+Q L PE K A+ +
Sbjct: 992 EGALSPGGVASLLRLPRGCGEQTMIYLAPTLAASRYLDKTEQWSTLPPETKDHAVDLIQK 1051
Query: 1011 GYQRQLNYKHYDGSYSTFGERYGRNQGNTWLTAFVLKTFAQARAYIFIDEAHITQALIWL 1070
GY R ++ DGSY+ + R +TWLTAFVLK + A+ + + + WL
Sbjct: 1052 GYMRIQQFRKADGSYAAWLSR----DSSTWLTAFVLKVLSLAQEQVGGSPEKLQETSNWL 1107
Query: 1071 SQRQKDNGCFRSSGSLLNNAIKGGV---EDEVTLSAYITIALLEIPLTV-----THPVVR 1122
+Q+ +G F+ +L+ +++GG+ ++ V L+A++TIAL L V P+ +
Sbjct: 1108 LSQQQADGSFQDPCPVLDRSMQGGLVGNDETVALTAFVTIALHH-GLAVFQDEGAEPLKQ 1166
Query: 1123 NALFCLESA----WKTAQEGDHGSHVYTKALLAYAFALA-GNQDKRKEVLKSLNEEAVKK 1177
+ A + A G G+H A+ AYA L D +L A +
Sbjct: 1167 RVEASISKANSFLGEKASAGLLGAHA--AAITAYALTLTKAPVDLLGVAHNNLMAMAQET 1224
Query: 1178 DNSVHW--------------ERPQKPKAPVGHFYEPQAPSAEVEMTSYVLLAYLTAQPAP 1223
++++W P+ P P+ PQAP+ +E T+Y LL L +
Sbjct: 1225 GDNLYWGSVTGSQSNAVSPTPAPRNPSDPM-----PQAPALWIETTAYALLHLLLHEGKA 1279
Query: 1224 TSEDLTSATNIVKWITKQQNAQGGFSSTQDTVVALHALSKYGAATFTRTGKAAQVTIQSS 1283
D SA W+T+Q + QGGF STQDTV+AL ALS Y A+ T + VT+ S+
Sbjct: 1280 EMADQASA-----WLTRQGSFQGGFRSTQDTVIALDALSAYWIASHTTEERGLNVTLSST 1334
Query: 1284 GTFSSK---FQVDNNNRLLLQQVSLPELPGEYSMKVTGEGCVYLQTSLKYNILPEKEEFP 1340
G K Q++N L++ L + ++KV G L+ YN+L K
Sbjct: 1335 GRNGFKSHALQLNNRQIRGLEEELQFSLGSKINVKVGGNSKGTLKVLRTYNVLDMKNTTC 1394
Query: 1341 FALGVQT-----------------------LPQTCDEPKAH----TSFQI---------- 1363
L ++ LP D+P A T Q+
Sbjct: 1395 QDLQIEVTVKGHVEYTMEANEDYEDYEYDELPAK-DDPDAPLQPVTPLQLFEGRRNRRRR 1453
Query: 1364 ---------SLSVSYT------GSRSASNMAIVDVKMVSGFIPLKPTVKMLE--RSNHVS 1406
V YT G S MAI DV ++SGF L+ ++ L +VS
Sbjct: 1454 EAPKVVEEQESRVHYTVCIWRNGKVGLSGMAIADVTLLSGFHALRADLEKLTSLSDRYVS 1513
Query: 1407 RTEVSSNHVLIYLDKVSNQTLSLFFTVLQDVPVRDLKPAIVKVYDYYETDEFAIAEYNAP 1466
E HVL+Y D V + F +Q+VPV ++PA +YDYY + Y AP
Sbjct: 1514 HFETEGPHVLLYFDSVPTSRECVGFEAVQEVPVGLVQPASATLYDYYNPERRCSVFYGAP 1573
Query: 1467 CSKDL 1471
L
Sbjct: 1574 SKSRL 1578
>gi|239740684 PREDICTED: similar to C4A protein isoform 1 [Homo
sapiens]
Length = 1744
Score = 296 bits (759), Expect = 8e-80
Identities = 381/1505 (25%), Positives = 611/1505 (40%), Gaps = 229/1505 (15%)
Query: 129 VFVQTDKSIYKPGQTVKFRVVSMDENFHPLNELIPLVYIQDPKGNRIAQWQSFQLEGGLK 188
+F+QTD+ IY PGQ V++RV ++D+ P + I V +++ G R+ + + + +
Sbjct: 141 LFLQTDQPIYNPGQRVRYRVFALDQKMRPSTDTIT-VMVENSHGLRVRKKEVYMPSSIFQ 199
Query: 189 Q-FSFPLSSEPFQGSYKVVVQKKSG--GRTEHPFTVEEFVLPKFEVQVTV--PKIITILE 243
F P SEP G++K+ + G + F V+++VLP FEV++T P I+T+
Sbjct: 200 DDFVIPDISEP--GTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKITPGKPYILTVPG 257
Query: 244 --EEMNVSVCGLYTYGKPVPG--HVTVSICRKYSDASDCHGEDSQAFCEKFSGQLNSHGC 299
+EM + + Y YGKPV G +V + + + G +SQ ++
Sbjct: 258 HLDEMQLDIQARYIYGKPVQGVAYVRFGLLDEDGKKTFFRGLESQTKLVNGQSHISLSKA 317
Query: 300 FYQQVKTKVFQLKRKEYEMKLHTEAQIQE-EGTVVELTGRQSSEITRTITKLSFVKVDSH 358
+Q K+ ++L+ A I E G +E S + L K H
Sbjct: 318 EFQDALEKLNMGITDLQGLRLYVAAAIIEYPGGEMEEAELTSWYFVSSPFSLDLSKTKRH 377
Query: 359 FRQGIPFFGQVRLVDGKGVP---IPNKVIFIRGNEANYYS----NATTDEHGLVQFSINT 411
G PF Q + + G P IP KV + + TD G V I
Sbjct: 378 LVPGAPFLLQALVREMSGSPASGIPVKVSATVSSPGSVPEVQDIQQNTDGSGQVSIPIII 437
Query: 412 TNVMGTSLTVRVNYKDRSPCYGYQWVSEEHEEAHHTAYLVFSPSKSFVHLE-PMSHELPC 470
+ + L + V+ P A T S F+ +E P S
Sbjct: 438 PQTI-SELQLSVSAGSPHPAI-----------ARLTVAAPPSGGPGFLSIEWPDSRPPRV 485
Query: 471 GHTQTVQAHYILNGGTLLGLKKLSFYYLIMAKGGIVRTGTHGLLVKQEDMKGHFSISIPV 530
G T + + +G T +YY+I+++G IV + +E + S+S+ V
Sbjct: 486 GDTLNLNLRAVGSGATFS-----HYYYMILSRGQIV-------FMNREPKRTLTSVSVFV 533
Query: 531 KSDIAPVARLLIYAVLPTGD-VIGDSAKYDVE-NCLANKVDLSFSPS-QSLPASHAHLRV 587
+AP A GD + +S + DV+ K++LS + Q L +
Sbjct: 534 DHHLAP--SFYFVAFYYHGDHPVANSLRVDVQAGACEGKLELSVDGAKQYRNGESVKLHL 591
Query: 588 TAAPQSVCALRAVDQSVLLM--KPDAELSASSVYNLLPEKDLTGFPGPLND--------- 636
++ AL A+D ++ K L+ V+ + DL PG +
Sbjct: 592 ETDSLALVALGALDTALYAAGSKSHKPLNMGKVFEAMNSYDLGCGPGGGDSALQVFQAAG 651
Query: 637 ----QDDEDCINRHNVYINGITYTPVSSTNEKDMYSFL----EDMGLKAFTNSK------ 682
D+ ++R ++ +T +K +F E +G A +K
Sbjct: 652 LAFSDGDQWTLSRKR-----LSCPKEKTTRKKRNVNFQKAINEKLGQYASPTAKRCCQDG 706
Query: 683 -IRKPKM--CPQ----LQQYEMHGP--------EGLRVGFYESDVMGRGHARLVHVEEPH 727
R P M C Q +QQ + P E LR + G A + EE
Sbjct: 707 VTRLPMMRSCEQRAARVQQPDCREPFLSCCQFAESLRKKSRDKGQAGLQRALEILQEEDL 766
Query: 728 TET----VRKYFPETWIWDLVVVNSAGVAEVGVTVPDTITEWKAGAFCLSEDAGLGISST 783
+ VR +FPE W+W + V+ + + + +PD++T W+ LS+ GL +++
Sbjct: 767 IDEDDIPVRSFFPENWLWRVETVDRFQI--LTLWLPDSLTTWEIHGLSLSKTKGLCVATP 824
Query: 784 ASLRAFQPFFVELTMPYSVIRGEAFTLKATVLNYLPKCIRVSVQLEASPAFLAVPVEKEQ 843
LR F+ F + L +P SV R E L+ + NYL K + VSV +
Sbjct: 825 VQLRVFREFHLHLRLPMSVRRFEQLELRPVLYNYLDKNLTVSVHVSPVEGLCLAGGGGLA 884
Query: 844 APHCICANGRQTVSWAVTPKSLGNVNFTVSAEALESQELCGTEVPSVPEHGRKDTVIKPL 903
+ A + V+++V P + V+ V A E P D V K L
Sbjct: 885 QQVLVPAGSARPVAFSVVPTAAAAVSLKVVARG-------SFEFPV------GDAVSKVL 931
Query: 904 LVEPEG-LEKETTFNSLLCPSGGEVSEELSLKLPPNVVEES-----ARASVSVLGDILGS 957
+E EG + +E L + E+ PN++ + R + S D LGS
Sbjct: 932 QIEKEGAIHREELVYELNPLDHRGRTLEIPGNSDPNMIPDGDFNSYVRVTASDPLDTLGS 991
Query: 958 ----AMQNTQNLLQMPYGCGEQNMVLFAPNIYVLDYLNETQQ---LTPEIKSKAIGYLNT 1010
+ +LL++P GCGEQ M+ AP + YL++T+Q L PE K A+ +
Sbjct: 992 EGALSPGGVASLLRLPRGCGEQTMIYLAPTLAASRYLDKTEQWSTLPPETKDHAVDLIQK 1051
Query: 1011 GYQRQLNYKHYDGSYSTFGERYGRNQGNTWLTAFVLKTFAQARAYIFIDEAHITQALIWL 1070
GY R ++ DGSY+ + R +TWLTAFVLK + A+ + + + WL
Sbjct: 1052 GYMRIQQFRKADGSYAAWLSR----DSSTWLTAFVLKVLSLAQEQVGGSPEKLQETSNWL 1107
Query: 1071 SQRQKDNGCFRSSGSLLNNAIKGGV---EDEVTLSAYITIALLEIPLTV-----THPVVR 1122
+Q+ +G F+ +L+ +++GG+ ++ V L+A++TIAL L V P+ +
Sbjct: 1108 LSQQQADGSFQDPCPVLDRSMQGGLVGNDETVALTAFVTIALHH-GLAVFQDEGAEPLKQ 1166
Query: 1123 NALFCLESA----WKTAQEGDHGSHVYTKALLAYAFALA-GNQDKRKEVLKSLNEEAVKK 1177
+ A + A G G+H A+ AYA L D +L A +
Sbjct: 1167 RVEASISKANSFLGEKASAGLLGAHA--AAITAYALTLTKAPVDLLGVAHNNLMAMAQET 1224
Query: 1178 DNSVHW--------------ERPQKPKAPVGHFYEPQAPSAEVEMTSYVLLAYLTAQPAP 1223
++++W P+ P P+ PQAP+ +E T+Y LL L +
Sbjct: 1225 GDNLYWGSVTGSQSNAVSPTPAPRNPSDPM-----PQAPALWIETTAYALLHLLLHEGKA 1279
Query: 1224 TSEDLTSATNIVKWITKQQNAQGGFSSTQDTVVALHALSKYGAATFTRTGKAAQVTIQSS 1283
D +A W+T+Q + QGGF STQDTV+AL ALS Y A+ T + VT+ S+
Sbjct: 1280 EMADQAAA-----WLTRQGSFQGGFRSTQDTVIALDALSAYWIASHTTEERGLNVTLSST 1334
Query: 1284 GTFSSK---FQVDNNNRLLLQQVSLPELPGEYSMKVTGEGCVYLQTSLKYNILPEKEEFP 1340
G K Q++N L++ L + ++KV G L+ YN+L K
Sbjct: 1335 GRNGFKSHALQLNNRQIRGLEEELQFSLGSKINVKVGGNSKGTLKVLRTYNVLDMKNTTC 1394
Query: 1341 FALGVQT-----------------------LPQTCDEPKAH----TSFQI---------- 1363
L ++ LP D+P A T Q+
Sbjct: 1395 QDLQIEVTVKGHVEYTMEANEDYEDYEYDELPAK-DDPDAPLQPVTPLQLFEGRRNRRRR 1453
Query: 1364 ---------SLSVSYT------GSRSASNMAIVDVKMVSGFIPLKPTVKMLE--RSNHVS 1406
V YT G S MAI DV ++SGF L+ ++ L +VS
Sbjct: 1454 EAPKVVEEQESRVHYTVCIWRNGKVGLSGMAIADVTLLSGFHALRADLEKLTSLSDRYVS 1513
Query: 1407 RTEVSSNHVLIYLDKVSNQTLSLFFTVLQDVPVRDLKPAIVKVYDYYETDEFAIAEYNAP 1466
E HVL+Y D V + F +Q+VPV ++PA +YDYY + Y AP
Sbjct: 1514 HFETEGPHVLLYFDSVPTSRECVGFEAVQEVPVGLVQPASATLYDYYNPERRCSVFYGAP 1573
Query: 1467 CSKDL 1471
L
Sbjct: 1574 SKSRL 1578
>gi|239740686 PREDICTED: similar to C4A protein isoform 2 [Homo
sapiens]
Length = 1698
Score = 290 bits (742), Expect = 7e-78
Identities = 366/1465 (24%), Positives = 598/1465 (40%), Gaps = 195/1465 (13%)
Query: 129 VFVQTDKSIYKPGQTVKFRVVSMDENFHPLNELIPLVYIQDPKGNRIAQWQSFQLEGGLK 188
+F+QTD+ IY PGQ V++RV ++D+ P + I V +++ G R+ + + + +
Sbjct: 141 LFLQTDQPIYNPGQRVRYRVFALDQKMRPSTDTIT-VMVENSHGLRVRKKEVYMPSSIFQ 199
Query: 189 Q-FSFPLSSEPFQGSYKVVVQKKSG--GRTEHPFTVEEFVLPKFEVQVTV--PKIITILE 243
F P SEP G++K+ + G + F V+++VLP FEV++T P I+T+
Sbjct: 200 DDFVIPDISEP--GTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKITPGKPYILTVPG 257
Query: 244 --EEMNVSVCGLYTYGKPVPG--HVTVSICRKYSDASDCHGEDSQAFCEKFSGQLNSHGC 299
+EM + + Y YGKPV G +V + + + G +SQ ++
Sbjct: 258 HLDEMQLDIQARYIYGKPVQGVAYVRFGLLDEDGKKTFFRGLESQTKLVNGQSHISLSKA 317
Query: 300 FYQQVKTKVFQLKRKEYEMKLHTEAQIQE-EGTVVELTGRQSSEITRTITKLSFVKVDSH 358
+Q K+ ++L+ A I E G +E S + L K H
Sbjct: 318 EFQDALEKLNMGITDLQGLRLYVAAAIIEYPGGEMEEAELTSWYFVSSPFSLDLSKTKRH 377
Query: 359 FRQGIPFFGQVRLVDGKGVP---IPNKVIFIRGNEANYYS----NATTDEHGLVQFSINT 411
G PF Q + + G P IP KV + + TD G V I
Sbjct: 378 LVPGAPFLLQALVREMSGSPASGIPVKVSATVSSPGSVPEVQDIQQNTDGSGQVSIPIII 437
Query: 412 TNVMGTSLTVRVNYKDRSPCYGYQWVSEEHEEAHHTAYLVFSPSKSFVHLE-PMSHELPC 470
+ + L + V+ P A T S F+ +E P S
Sbjct: 438 PQTI-SELQLSVSAGSPHPAI-----------ARLTVAAPPSGGPGFLSIEWPDSRPPRV 485
Query: 471 GHTQTVQAHYILNGGTLLGLKKLSFYYLIMAKGGIVRTGTHGLLVKQEDMKGHFSISIPV 530
G T + + +G T +YY+I+++G IV + +E + S+S+ V
Sbjct: 486 GDTLNLNLRAVGSGATFS-----HYYYMILSRGQIV-------FMNREPKRTLTSVSVFV 533
Query: 531 KSDIAPVARLLIYAVLPTGD-VIGDSAKYDVE-NCLANKVDLSFSPS-QSLPASHAHLRV 587
+AP A GD + +S + DV+ K++LS + Q L +
Sbjct: 534 DHHLAP--SFYFVAFYYHGDHPVANSLRVDVQAGACEGKLELSVDGAKQYRNGESVKLHL 591
Query: 588 TAAPQSVCALRAVDQSVLLM--KPDAELSASSVYNLLPEKDLTGFPGPLND--------- 636
++ AL A+D ++ K L+ V+ + DL PG +
Sbjct: 592 ETDSLALVALGALDTALYAAGSKSHKPLNMGKVFEAMNSYDLGCGPGGGDSALQVFQAAG 651
Query: 637 ----QDDEDCINRHNVYINGITYTPVSSTNEKDMYSFL----EDMGLKAFTNSK------ 682
D+ ++R ++ +T +K +F E +G A +K
Sbjct: 652 LAFSDGDQWTLSRKR-----LSCPKEKTTRKKRNVNFQKAINEKLGQYASPTAKRCCQDG 706
Query: 683 -IRKPKM--CPQ----LQQYEMHGP--------EGLRVGFYESDVMGRGHARLVHVEEPH 727
R P M C Q +QQ + P E LR + G A + EE
Sbjct: 707 VTRLPMMRSCEQRAARVQQPDCREPFLSCCQFAESLRKKSRDKGQAGLQRALEILQEEDL 766
Query: 728 TET----VRKYFPETWIWDLVVVNSAGVAEVGVTVPDTITEWKAGAFCLSEDAGLGISST 783
+ VR +FPE W+W + V+ + + + +PD++T W+ LS+ GL +++
Sbjct: 767 IDEDDIPVRSFFPENWLWRVETVDRFQI--LTLWLPDSLTTWEIHGLSLSKTKGLCVATP 824
Query: 784 ASLRAFQPFFVELTMPYSVIRGEAFTLKATVLNYLPKCIRVSVQLEASPAFLAVPVEKEQ 843
LR F+ F + L +P SV R E L+ + NYL K + VSV +
Sbjct: 825 VQLRVFREFHLHLRLPMSVRRFEQLELRPVLYNYLDKNLTVSVHVSPVEGLCLAGGGGLA 884
Query: 844 APHCICANGRQTVSWAVTPKSLGNVNFTVSAEALESQELCGTEVPSVPEHGRKDTVIKPL 903
+ A + V+++V P + V+ V A E P D V K L
Sbjct: 885 QQVLVPAGSARPVAFSVVPTAAAAVSLKVVARG-------SFEFPV------GDAVSKVL 931
Query: 904 LVEPEG-LEKETTFNSLLCPSGGEVSEELSLKLPPNVVEES-----ARASVSVLGDILGS 957
+E EG + +E L + E+ PN++ + R + S D LGS
Sbjct: 932 QIEKEGAIHREELVYELNPLDHRGRTLEIPGNSDPNMIPDGDFNSYVRVTASDPLDTLGS 991
Query: 958 ----AMQNTQNLLQMPYGCGEQNMVLFAPNIYVLDYLNETQQ---LTPEIKSKAIGYLNT 1010
+ +LL++P GCGEQ M+ AP + YL++T+Q L PE K A+ +
Sbjct: 992 EGALSPGGVASLLRLPRGCGEQTMIYLAPTLAASRYLDKTEQWSTLPPETKDHAVDLIQK 1051
Query: 1011 GYQRQLNYKHYDGSYSTFGERYGRNQGNTWLTAFVLKTFAQARAYIFIDEAHITQALIWL 1070
GY R ++ DGSY+ + R +TWLTAFVLK + A+ + + + WL
Sbjct: 1052 GYMRIQQFRKADGSYAAWLSR----DSSTWLTAFVLKVLSLAQEQVGGSPEKLQETSNWL 1107
Query: 1071 SQRQKDNGCFRSSGSLLNNAIKGGV---EDEVTLSAYITIALLEIPLTV-----THPVVR 1122
+Q+ +G F+ +L+ +++GG+ ++ V L+A++TIAL L V P+ +
Sbjct: 1108 LSQQQADGSFQDPCPVLDRSMQGGLVGNDETVALTAFVTIALHH-GLAVFQDEGAEPLKQ 1166
Query: 1123 NALFCLESA----WKTAQEGDHGSHVYTKALLAYAFALA-GNQDKRKEVLKSLNEEAVKK 1177
+ A + A G G+H A+ AYA L D +L A +
Sbjct: 1167 RVEASISKANSFLGEKASAGLLGAHA--AAITAYALTLTKAPVDLLGVAHNNLMAMAQET 1224
Query: 1178 DNSVHW--------------ERPQKPKAPVGHFYEPQAPSAEVEMTSYVLLAYLTAQPAP 1223
++++W P+ P P+ PQAP+ +E T+Y LL L +
Sbjct: 1225 GDNLYWGSVTGSQSNAVSPTPAPRNPSDPM-----PQAPALWIETTAYALLHLLLHEGKA 1279
Query: 1224 TSEDLTSATNIVKWITKQQNAQGGFSSTQDTVVALHALSKYGAATFTRTGKAAQVTIQSS 1283
D +A W+T+Q + QGGF STQDTV+AL ALS Y A+ T + VT+ S+
Sbjct: 1280 EMADQAAA-----WLTRQGSFQGGFRSTQDTVIALDALSAYWIASHTTEERGLNVTLSST 1334
Query: 1284 GTFSSK---FQVDNNNRLLLQQVSLPELPGEYSMKVTGEGCVYLQTSLKYNILPEKEEFP 1340
G K Q++N L++ L + ++KV G L+ YN+L K
Sbjct: 1335 GRNGFKSHALQLNNRQIRGLEEELQFSLGSKINVKVGGNSKGTLKVLRTYNVLDMKNTTC 1394
Query: 1341 FALGVQTLPQTCDEPKAHTSFQISLSVSY----------TGSRSASNMAIVDVKMVSGFI 1390
L ++ K H + + + Y A + +++ G
Sbjct: 1395 QDLQIEV------TVKGHVEYTMEANEDYEDYEYDELPAKDDPDAPLQPVTPLQLFEGRR 1448
Query: 1391 PLK----PTVKMLERSNHVSRTEVSSNHVLIYLDKVSNQTLSLFFTVLQDVPVRDLKPAI 1446
+ P + L +VS E HVL+Y D V + F +Q+VPV ++PA
Sbjct: 1449 NRRRREAPKLTSLS-DRYVSHFETEGPHVLLYFDSVPTSRECVGFEAVQEVPVGLVQPAS 1507
Query: 1447 VKVYDYYETDEFAIAEYNAPCSKDL 1471
+YDYY + Y AP L
Sbjct: 1508 ATLYDYYNPERRCSVFYGAPSKSRL 1532
>gi|38016947 complement component 5 preproprotein [Homo sapiens]
Length = 1676
Score = 268 bits (686), Expect = 2e-71
Identities = 346/1556 (22%), Positives = 636/1556 (40%), Gaps = 204/1556 (13%)
Query: 31 YMVLVPSLLHTETTEKGCVLLSYLNETVTVSASLESVRGNRSLFTD----LEAENDVLHC 86
Y++ P + +E + + E + S++S + ++ L +EN +
Sbjct: 23 YVISAPKIFRVGASENIVIQVYGYTEAFDATISIKSYPDKKFSYSSGHVHLSSENKFQNS 82
Query: 87 VAFAV-PKSSSNEEVMFLTVQVKGPTQEFKKRTTVMVKNEDSLVFVQTDKSIYKPGQTVK 145
+ PK + V ++ ++ F K + + ++ +F+ TDK +Y P Q+VK
Sbjct: 83 AILTIQPKQLPGGQNPVSYVYLEVVSKHFSKSKRMPITYDNGFLFIHTDKPVYTPDQSVK 142
Query: 146 FRVVSMDENFHPLNELIPLVYIQDPKGNRIAQWQSFQLEGGLKQFSFPLSSEPFQGSYKV 205
RV S++++ P L +I DP+G+ + + G + F + S P G + +
Sbjct: 143 VRVYSLNDDLKPAKRETVLTFI-DPEGSEVDMVEEIDHIGIISFPDFKIPSNPRYGMWTI 201
Query: 206 VVQKKSGGRTEHP--FTVEEFVLPKFEVQVTVPKIITILEEEMN--VSVCGLYTYGKPVP 261
+ K T F V+E+VLP F V + + N +++ Y Y K V
Sbjct: 202 KAKYKEDFSTTGTAYFEVKEYVLPHFSVSIEPEYNFIGYKNFKNFEITIKARYFYNKVV- 260
Query: 262 GHVTVSICRKYSDASDCHGEDSQAFCEKFSGQLNSHGCFYQQVKTKVFQLKRKEYEMKLH 321
+ + D + + + +G ++ + Y ++
Sbjct: 261 --TEADVYITFGIREDLKDDQKEMMQTAMQNTMLINGIAQVTFDSETAVKELSYYSLEDL 318
Query: 322 TEAQIQEEGTVVELTGRQSSEI-------TRTITKLSFVKVDSHFRQGIPFFGQVRLVDG 374
+ TV+E TG S E + KL+ V + GIP+ +V++ D
Sbjct: 319 NNKYLYIAVTVIESTGGFSEEAEIPGIKYVLSPYKLNLVATPLFLKPGIPYPIKVQVKDS 378
Query: 375 K-----GVPIPNKVIFIRGNEANY----YSNATTDEHGLVQFSINTTNVMGTSLTV-RVN 424
GVP+ I N+ + T + G+ F +N + + +TV N
Sbjct: 379 LDQLVGGVPVTLNAQTIDVNQETSDLDPSKSVTRVDDGVASFVLN----LPSGVTVLEFN 434
Query: 425 YKDRSPCYGYQWVSEEHEEAHHTAYLVFSPSKSFVHLEPMSHELPCGH----TQTVQAHY 480
K +P + ++ E AY S S ++ L G T ++ Y
Sbjct: 435 VKTDAPDLPEE--NQAREGYRAIAYSSLSQSYLYIDWTDNHKALLVGEHLNIIVTPKSPY 492
Query: 481 ILNGGTLLGLKKLSFY-YLIMAKGGIVRTGTHGLLVKQEDMKGHFSISIPVKSDIAPVAR 539
I K++ Y YLI++KG I+ GT ++ + SI+IPV ++ P +R
Sbjct: 493 I---------DKITHYNYLILSKGKIIHFGTR----EKFSDASYQSINIPVTQNMVPSSR 539
Query: 540 LLIYAVLP---TGDVIGDSAKYDVENCLANKVDLSFSPSQSL--PASHAHLRVTAAPQSV 594
LL+Y ++ T +++ DS ++E N++ + SP P L + S
Sbjct: 540 LLVYYIVTGEQTAELVSDSVWLNIEEKCGNQLQVHLSPDADAYSPGQTVSLNMATGMDSW 599
Query: 595 CALRAVDQSVLLMKPDAELSASSVYNLLPEKDL-TGFPGPLNDQDDEDCINRHNVYINGI 653
AL AVD +V ++ A+ V+ L + DL G G LN N + ++ G+
Sbjct: 600 VALAAVDSAVYGVQRGAKKPLERVFQFLEKSDLGCGAGGGLN--------NANVFHLAGL 651
Query: 654 TYTPVSSTNE---------------KDMYSFLEDMGLK---------AFTNSKIRKPKMC 689
T+ ++ ++ + + +E++ K + + + + C
Sbjct: 652 TFLTNANADDSQENDEPCKEILRPRRTLQKKIEEIAAKYKHSVVKKCCYDGACVNNDETC 711
Query: 690 PQLQQYEMHGPE-------------GLRVGFYESDV-MGRGHAR-LVHVEEPHTETVRKY 734
Q GP LR D+ +GR H + L+ V +P +R Y
Sbjct: 712 EQRAARISLGPRCIKAFTECCVVASQLRANISHKDMQLGRLHMKTLLPVSKPE---IRSY 768
Query: 735 FPETWIWDLVVVNSAGVAEVGVTVPDTITEWKAGAFCLSEDAGLGISSTASLRAFQPFFV 794
FPE+W+W++ +V ++ +PD++T W+ +S + G+ ++ T + F+ F+
Sbjct: 769 FPESWLWEVHLVPRR--KQLQFALPDSLTTWEIQGVGIS-NTGICVADTVKAKVFKDVFL 825
Query: 795 ELTMPYSVIRGEAFTLKATVLNYLPKCIRVSVQLEASPAFL-----AVPVEKEQAPHCIC 849
E+ +PYSV+RGE LK TV NY ++ V++ A + + ++ C+
Sbjct: 826 EMNIPYSVVRGEQIQLKGTVYNYRTSGMQFCVKMSAVEGICTSESPVIDHQGTKSSKCVR 885
Query: 850 ----ANGRQTVSWAVTPKSLGNVNFTVSAEALESQELCGTEVPSVPEHGRKDTVIKPLLV 905
+ V++ V P +G N S E +E+ ++K L V
Sbjct: 886 QKVEGSSSHLVTFTVLPLEIGLHNINFSLETWFGKEI----------------LVKTLRV 929
Query: 906 EPEGLEKETTFNSLLCPSG--GEVS--EELSLKLPPNVVEES-ARASVSVLGDILGS--- 957
PEG+++E+ L P G G +S +E ++P ++V ++ + +SV G ++G
Sbjct: 930 VPEGVKRESYSGVTLDPRGIYGTISRRKEFPYRIPLDLVPKTEIKRILSVKGLLVGEILS 989
Query: 958 ---AMQNTQNLLQMPYGCGEQNMVLFAPNIYVLDYLNETQQLT-----PEI-KSKAIGYL 1008
+ + L +P G E ++ P YV YL P I K K L
Sbjct: 990 AVLSQEGINILTHLPKGSAEAELMSVVPVFYVFHYLETGNHWNIFHSDPLIEKQKLKKKL 1049
Query: 1009 NTGYQRQLNYKHYDGSYSTFGERYGRNQGNTWLTAFVLKTFAQARAYIFIDEAHITQALI 1068
G ++Y++ D SYS + +TWLTAF L+ Q Y+ ++ I +L+
Sbjct: 1050 KEGMLSIMSYRNADYSYSV----WKGGSASTWLTAFALRVLGQVNKYVEQNQNSICNSLL 1105
Query: 1069 WLSQR-QKDNGCFRSSGSLLNNAIKGGV-----EDEVTLSAYITIALLE----IPLT-VT 1117
WL + Q DNG F+ + ++G + E+ + L+A+ I + + PL +
Sbjct: 1106 WLVENYQLDNGSFKENSQYQPIKLQGTLPVEARENSLYLTAFTVIGIRKAFDICPLVKID 1165
Query: 1118 HPVVRNALFCLESAWKTAQEGDHGSHVYTKALLAYAFALAGNQDKR-KEVLKSLNEEAVK 1176
+++ F LE+ +T A+ AYA +L + + ++ +L EA+
Sbjct: 1166 TALIKADNFLLENTLP-------AQSTFTLAISAYALSLGDKTHPQFRSIVSALKREALV 1218
Query: 1177 KDNSVHWERPQKPKAPVGHFYEPQAPSAE-VEMTSYVLLAYLTAQPAPTSEDLTSATNIV 1235
K N + R K P +A VE T+Y LL L +D+ ++
Sbjct: 1219 KGNPPIY-RFWKDNLQHKDSSVPNTGTARMVETTAYALLTSLNL------KDINYVNPVI 1271
Query: 1236 KWITKQQNAQGGFSSTQDTVVALHALSKYG-AATFTRTGKAAQVTIQSSGTFSSKFQVDN 1294
KW++++Q GGF STQDT+ A+ L++Y R V+ + G + D
Sbjct: 1272 KWLSEEQRYGGGFYSTQDTINAIEGLTEYSLLVKQLRLSMDIDVSYKHKGALHNYKMTDK 1331
Query: 1295 NNRLLLQQVSLPELPGEYSMKVTGEG---CVYLQTSLKYNILPEKEEFPFALGVQTLPQT 1351
N L + V + L + + TG G T++ + +E F L + T
Sbjct: 1332 N--FLGRPVEV--LLNDDLIVSTGFGSGLATVHVTTVVHKTSTSEEVCSFYLKIDTQDIE 1387
Query: 1352 CDEPKAHTSF---QISLSVSYTGSR----SASNMAIVDVKMVSGFIPLKPTVKMLERSNH 1404
+ + + +I SY SR S S+ A++D+ + +G + +K L
Sbjct: 1388 ASHYRGYGNSDYKRIVACASYKPSREESSSGSSHAVMDISLPTGISANEEDLKALVEGVD 1447
Query: 1405 VSRT--EVSSNHVLIYLDKV-SNQTLSLFFTVLQDVPVRDLKPAIVKVYDYYETDE 1457
T ++ HV++ L+ + S+ L + F + + V L PA VY+Y+ D+
Sbjct: 1448 QLFTDYQIKDGHVILQLNSIPSSDFLCVRFRIFELFEVGFLSPATFTVYEYHRPDK 1503
>gi|115298678 complement component 3 precursor [Homo sapiens]
Length = 1663
Score = 214 bits (544), Expect = 6e-55
Identities = 202/773 (26%), Positives = 349/773 (45%), Gaps = 82/773 (10%)
Query: 732 RKYFPETWIWDLVVV-----NSAGVAEVGVTVPDTITEWKAGAFCLSEDAGLGISSTASL 786
R FPE+W+W++ + N + + + D+IT W+ A +S+ G+ ++ +
Sbjct: 764 RSEFPESWLWNVEDLKEPPKNGISTKLMNIFLKDSITTWEILAVSMSDKKGICVADPFEV 823
Query: 787 RAFQPFFVELTMPYSVIRGEAFTLKATVLNYLP-KCIRVSVQLEASPAF--LAVPVEKEQ 843
Q FF++L +PYSV+R E ++A + NY + ++V V+L +PAF LA + Q
Sbjct: 824 TVMQDFFIDLRLPYSVVRNEQVEIRAVLYNYRQNQELKVRVELLHNPAFCSLATTKRRHQ 883
Query: 844 APHCICANGRQTVSWAVTPKSLGNVNFTVSAEALESQELCGT--EVPSVPEHGRKDTVIK 901
I +V + + P G V A G + VPE R + +
Sbjct: 884 QTVTIPPKSSLSVPYVIVPLKTGLQEVEVKAAVYHHFISDGVRKSLKVVPEGIRMNKTVA 943
Query: 902 PLLVEPEGLEKETTFNSLLCPSGGEVSEELSLKLPPNVVEESARASVSVLGDILGSAM-- 959
++PE L +E + P+ +LS ++P E + + + A+
Sbjct: 944 VRTLDPERLGREGVQKEDIPPA------DLSDQVPDTESETRILLQGTPVAQMTEDAVDA 997
Query: 960 QNTQNLLQMPYGCGEQNMVLFAPNIYVLDYLNETQQLTP---EIKSKAIGYLNTGYQRQL 1016
+ ++L+ P GCGEQNM+ P + + YL+ET+Q E + A+ + GY +QL
Sbjct: 998 ERLKHLIVTPSGCGEQNMIGMTPTVIAVHYLDETEQWEKFGLEKRQGALELIKKGYTQQL 1057
Query: 1017 NYKHYDGSYSTFGERYGRNQGNTWLTAFVLKTFAQARAYIFIDEAHITQALIWL-SQRQK 1075
++ +++ F +R +TWLTA+V+K F+ A I ID + A+ WL ++QK
Sbjct: 1058 AFRQPSSAFAAFVKR----APSTWLTAYVVKVFSLAVNLIAIDSQVLCGAVKWLILEKQK 1113
Query: 1076 DNGCFRSSGSLLNNAIKGGV----EDEVTLSAYITIALLEIPLTVTHPV------VRNAL 1125
+G F+ +++ + GG+ E ++ L+A++ I+L E V + A
Sbjct: 1114 PDGVFQEDAPVIHQEMIGGLRNNNEKDMALTAFVLISLQEAKDICEEQVNSLPGSITKAG 1173
Query: 1126 FCLESAWKTAQEGDHGSHVYTKALLAYAFALAGNQDKRKEVLKSLNEEAVKKDNSVHWER 1185
LE+ + Q YT A+ YA A G + K L LN+ + WE
Sbjct: 1174 DFLEANYMNLQRS------YTVAIAGYALAQMG---RLKGPL--LNKFLTTAKDKNRWED 1222
Query: 1186 PQKPKAPVGHFYEPQAPSAEVEMTSYVLLAYLTAQPAPTSEDLTSATNIVKWITKQQNAQ 1245
P K Y VE TSY LLA L +D +V+W+ +Q+
Sbjct: 1223 PGK------QLY-------NVEATSYALLALLQL------KDFDFVPPVVRWLNEQRYYG 1263
Query: 1246 GGFSSTQDTVVALHALSKYGAATFTRTGKAAQVTIQ-SSGTFSSKFQVDNNNRLLLQQVS 1304
GG+ STQ T + AL++Y V++Q S + ++ + LL+
Sbjct: 1264 GGYGSTQATFMVFQALAQYQKDAPDHQELNLDVSLQLPSRSSKITHRIHWESASLLRSEE 1323
Query: 1305 LPELPGEYSMKVTGEGCVYLQTSLKYNILPEKE----EFPFALGVQTLPQTCDEPK-AHT 1359
E G +++ G+G L Y+ + + +F + ++ P+T P+ A
Sbjct: 1324 TKENEG-FTVTAEGKGQGTLSVVTMYHAKAKDQLTCNKFDLKVTIKPAPETEKRPQDAKN 1382
Query: 1360 SFQISLSVSYTGSRSASNMAIVDVKMVSGFIPLKPTVKMLER--SNHVSRTEVSS----- 1412
+ + + Y G + A+ M+I+D+ M++GF P +K L ++S+ E+
Sbjct: 1383 TMILEICTRYRGDQDAT-MSILDISMMTGFAPDTDDLKQLANGVDRYISKYELDKAFSDR 1441
Query: 1413 NHVLIYLDKVS-NQTLSLFFTVLQDVPVRDLKPAIVKVYDYYETDEFAIAEYN 1464
N ++IYLDKVS ++ L F V Q V ++P VKVY YY +E Y+
Sbjct: 1442 NTLIIYLDKVSHSEDDCLAFKVHQYFNVELIQPGAVKVYAYYNLEESCTRFYH 1494
Score = 138 bits (348), Expect = 3e-32
Identities = 165/659 (25%), Positives = 287/659 (43%), Gaps = 62/659 (9%)
Query: 9 PSLVLLLLVLLPTDASVSGKPQYMVLVPSLLHTETTEKGCVLLSYLNETVTVSASLESVR 68
PSL+LLLL LP G P Y ++ P++L E+ E + V V+ ++
Sbjct: 7 PSLLLLLLTHLPL---ALGSPMYSIITPNILRLESEETMVLEAHDAQGDVPVTVTVHDFP 63
Query: 69 GNRSLF----TDLEAENDVLHCVAFAVPKS----SSNEEVMFLTVQVKGPTQEFKKRTTV 120
G + + T L + + V F +P + S F+TVQ TQ +K V
Sbjct: 64 GKKLVLSSEKTVLTPATNHMGNVTFTIPANREFKSEKGRNKFVTVQATFGTQVVEK--VV 121
Query: 121 MVKNEDSLVFVQTDKSIYKPGQTVKFRVVSMDENFHPLNELIPLVYIQDPKGNRIAQWQ- 179
+V + +F+QTDK+IY PG TV +R+ +++ P+ + +V I++P+G + Q
Sbjct: 122 LVSLQSGYLFIQTDKTIYTPGSTVLYRIFTVNHKLLPVGRTV-MVNIENPEGIPVKQDSL 180
Query: 180 SFQLEGGLKQFSFPLSSEPFQGSYKVVVQKKSGGRT--EHPFTVEEFVLPKFEVQV-TVP 236
S Q + G+ S+ + G +K+ ++ + F V+E+VLP FEV V
Sbjct: 181 SSQNQLGVLPLSWDIPELVNMGQWKIRAYYENSPQQVFSTEFEVKEYVLPSFEVIVEPTE 240
Query: 237 KIITILEEE-MNVSVCGLYTYGKPVPGHVTVSICRKYSDASDCHGEDSQAF-CEKFSGQL 294
K I E+ + V++ + YGK V G V + + E + E SG++
Sbjct: 241 KFYYIYNEKGLEVTITARFLYGKKVEGTAFVIFGIQDGEQRISLPESLKRIPIEDGSGEV 300
Query: 295 NSHGCFYQQVKTKVFQLKRKE--YEMKLHTEAQ-IQEEGTVVELTGRQSSEITRTITKLS 351
++V Q R E L+ A I G+ + R I + ++
Sbjct: 301 ----VLSRKVLLDGVQNPRAEDLVGKSLYVSATVILHSGSDMVQAERSGIPIVTSPYQIH 356
Query: 352 FVKVDSHFRQGIPFFGQVRLVDGKGVPIPNKVIFIRGNEANYYSNATTDEHGLVQFSINT 411
F K +F+ G+PF V + + G P + ++G + + T G+ + SINT
Sbjct: 357 FTKTPKYFKPGMPFDLMVFVTNPDGSPAYRVPVAVQGEDT---VQSLTQGDGVAKLSINT 413
Query: 412 -TNVMGTSLTVRVNYKDRSPCYGYQWVSEEHEEAHHT----AYLVFSPSKSFVHLEPMSH 466
+ S+TVR ++ S E E+A T Y S +++HL +
Sbjct: 414 HPSQKPLSITVRTKKQELS----------EAEQATRTMQALPYSTVGNSNNYLHLSVLRT 463
Query: 467 ELPCGHTQTVQAHYILNGGTLLGLKKLSFYYLIMAKGGIVRTGTHGLLVKQEDMKGHFSI 526
EL G +T+ +++L K + YLIM KG +++ G +Q G +
Sbjct: 464 ELRPG--ETLNVNFLLRMDRAHEAKIRYYTYLIMNKGRLLKAG------RQVREPGQDLV 515
Query: 527 SIP--VKSDIAPVARLLIYAVL----PTGDVIGDSAKYDV-ENCLANKVDLS--FSPSQS 577
+P + +D P RL+ Y L +V+ DS DV ++C+ + V S Q
Sbjct: 516 VLPLSITTDFIPSFRLVAYYTLIGASGQREVVADSVWVDVKDSCVGSLVVKSGQSEDRQP 575
Query: 578 LPASHAHLRVTAAPQSVCALRAVDQSVLLMKPDAELSASSVYNLLPEKDLTGFPGPLND 636
+P L++ + L AVD+ V ++ +L+ S +++++ + D+ PG D
Sbjct: 576 VPGQQMTLKIEGDHGARVVLVAVDKGVFVLNKKNKLTQSKIWDVVEKADIGCTPGSGKD 634
>gi|169218213 PREDICTED: similar to complement component C3, partial
[Homo sapiens]
Length = 1295
Score = 172 bits (436), Expect = 2e-42
Identities = 150/559 (26%), Positives = 254/559 (45%), Gaps = 66/559 (11%)
Query: 732 RKYFPETWIWDLVVV-----NSAGVAEVGVTVPDTITEWKAGAFCLSEDAGLGISSTASL 786
R FPE+W+W++ + N + + + D+IT W+ A +S+ G+ ++ +
Sbjct: 764 RSEFPESWLWNVEDLKEPPKNGISTKLMNIFLKDSITTWEILAVSMSDKKGICVADPFEV 823
Query: 787 RAFQPFFVELTMPYSVIRGEAFTLKATVLNYLP-KCIRVSVQLEASPAF--LAVPVEKEQ 843
Q FF++L +PYSV+R E ++A + NY + ++V V+L +PAF LA + Q
Sbjct: 824 TVMQDFFIDLRLPYSVVRNEQVEIRAVLYNYRQNQELKVRVELLHNPAFCSLATTKRRHQ 883
Query: 844 APHCICANGRQTVSWAVTPKSLGNVNFTVSAEALESQELCGT--EVPSVPEHGRKDTVIK 901
I +V + + P G V A G + VPE R + +
Sbjct: 884 QTVTIPPKSSLSVPYVIVPLKTGLQEVEVKAAVYHHFISDGVRKSLKVVPEGIRMNKTVA 943
Query: 902 PLLVEPEGLEKETTFNSLLCPSGGEVSEELSLKLPPNVVEESARASVSVLGDILGSAM-- 959
++PE L +E + P+ +LS ++P E + + + A+
Sbjct: 944 VRTLDPERLGREGVQKEDIPPA------DLSDQVPDTESETRILLQGTPVAQMTEDAVDA 997
Query: 960 QNTQNLLQMPYGCGEQNMVLFAPNIYVLDYLNETQQLTP---EIKSKAIGYLNTGYQRQL 1016
+ ++L+ P GCGEQNM+ P + + YL+ET+Q E + A+ + GY +QL
Sbjct: 998 ERLKHLIVTPSGCGEQNMIGMTPTVIAVHYLDETEQWEKFGLEKRQGALELIKKGYTQQL 1057
Query: 1017 NYKHYDGSYSTFGERYGRNQGNTWLTAFVLKTFAQARAYIFIDEAHITQALIWL-SQRQK 1075
++ +++ F +R +TWLTA+V+K F+ A I ID + A+ WL ++QK
Sbjct: 1058 AFRQPSSAFAAFVKR----APSTWLTAYVVKVFSLAVNLIAIDSQVLCGAVKWLILEKQK 1113
Query: 1076 DNGCFRSSGSLLNNAIKGGV----EDEVTLSAYITIALLEIPLTVTHPV------VRNAL 1125
+G F+ +++ + GG+ E ++ L+A++ I+L E V + A
Sbjct: 1114 PDGVFQEDAPVIHQEMIGGLRNNNEKDMALTAFVLISLQEAKDICEEQVNSLPGSITKAG 1173
Query: 1126 FCLESAWKTAQEGDHGSHVYTKALLAYAFALAGNQDKRKEVLKSLNEEAVKKDNSVHWER 1185
LE+ + Q YT A+ YA A G + K L LN+ + WE
Sbjct: 1174 DFLEANYMNLQRS------YTVAIAGYALAQMG---RLKGPL--LNKFLTTAKDKNRWED 1222
Query: 1186 PQKPKAPVGHFYEPQAPSAEVEMTSYVLLAYLTAQPAPTSEDLTSATNIVKWITKQQNAQ 1245
P K Y VE TSY LLA L +D +V+W+ +Q+
Sbjct: 1223 PGK------QLY-------NVEATSYALLALLQL------KDFDFVPPVVRWLNEQRYYG 1263
Query: 1246 GGFSSTQDTVVALHALSKY 1264
GG+ STQ T + AL++Y
Sbjct: 1264 GGYGSTQATFMVFQALAQY 1282
Score = 138 bits (348), Expect = 3e-32
Identities = 166/662 (25%), Positives = 287/662 (43%), Gaps = 68/662 (10%)
Query: 9 PSLVLLLLVLLPTDASVSGKPQYMVLVPSLLHTETTEKGCVLLSYLNETVTVSASLESVR 68
PSL+LLLL LP G P Y ++ P++L E+ E + V V+ ++
Sbjct: 7 PSLLLLLLTHLPL---ALGSPMYSIITPNILRLESEETMVLEAHDAQGDVPVTVTVHDFP 63
Query: 69 GNRSLF----TDLEAENDVLHCVAFAVPKS----SSNEEVMFLTVQVKGPTQEFKKRTTV 120
G + + T L + + V F +P + S F+TVQ TQ +K V
Sbjct: 64 GKKLVLSSEKTVLTPATNHMGNVTFTIPANREFKSEKGRNKFVTVQATFGTQVVEK--VV 121
Query: 121 MVKNEDSLVFVQTDKSIYKPGQTVKFRVVSMDENFHPLNELIPLVYIQDPKGNRIAQWQ- 179
+V + +F+QTDK+IY PG TV +R+ +++ P+ + +V I++P+G + Q
Sbjct: 122 LVSLQSGYLFIQTDKTIYTPGSTVLYRIFTVNHKLLPVGRTV-MVNIENPEGIPVKQDSL 180
Query: 180 SFQLEGGLKQFSFPLSSEPFQGSYKVVVQKKSGGRT--EHPFTVEEFVLPKFEVQV-TVP 236
S Q + G+ S+ + G +K+ ++ + F V+E+VLP FEV V
Sbjct: 181 SSQNQLGVLPLSWDIPELVNMGQWKIRAYYENSPQQVFSTEFEVKEYVLPSFEVIVEPTE 240
Query: 237 KIITILEEE-MNVSVCGLYTYGKPVPGHVTVSICRKYSDASDCHGEDSQAFCEKFSGQLN 295
K I E+ + V++ + YGK V G T + D GE + E
Sbjct: 241 KFYYIYNEKGLEVTITARFLYGKKVEG--TAFVIFGIQD-----GEQRISLPESLKRIPI 293
Query: 296 SHGCFYQQVKTKVF-----QLKRKEYEMK-LHTEAQ-IQEEGTVVELTGRQSSEITRTIT 348
G + KV L+ ++ K L+ A I G+ + R I +
Sbjct: 294 EDGSGEVVLSRKVLLDGVQNLRAEDLVGKSLYVSATVILHSGSDMVQAERSGIPIVTSPY 353
Query: 349 KLSFVKVDSHFRQGIPFFGQVRLVDGKGVPIPNKVIFIRGNEANYYSNATTDEHGLVQFS 408
++ F K +F+ G+PF V + + G P + ++G + + T G+ + S
Sbjct: 354 QIHFTKTPKYFKPGMPFDLMVFVTNPDGSPAYRVPVAVQGEDT---VQSLTQGDGVAKLS 410
Query: 409 INT-TNVMGTSLTVRVNYKDRSPCYGYQWVSEEHEEAHHT----AYLVFSPSKSFVHLEP 463
INT + S+TVR ++ S E E+A T Y S +++HL
Sbjct: 411 INTHPSQKPLSITVRTKKQELS----------EAEQATRTMQALPYSTVGNSNNYLHLSV 460
Query: 464 MSHELPCGHTQTVQAHYILNGGTLLGLKKLSFYYLIMAKGGIVRTGTHGLLVKQEDMKGH 523
+ EL G +T+ +++L K + YLIM KG +++ G +Q G
Sbjct: 461 LRTELRPG--ETLNVNFLLRMDRAHEAKIRYYTYLIMNKGRLLKAG------RQVREPGQ 512
Query: 524 FSISIP--VKSDIAPVARLLIYAVL----PTGDVIGDSAKYDV-ENCLANKVDLS--FSP 574
+ +P + +D P RL+ Y L +V+ DS DV ++C+ + V S
Sbjct: 513 DLVVLPLSITTDFIPSFRLVAYYTLIGASGQREVVADSVWVDVKDSCVGSLVVKSGQSED 572
Query: 575 SQSLPASHAHLRVTAAPQSVCALRAVDQSVLLMKPDAELSASSVYNLLPEKDLTGFPGPL 634
Q +P L++ + L AVD+ V ++ +L+ S +++++ + D+ PG
Sbjct: 573 RQPVPGQQMTLKIEGDHGARVVLVAVDKGVFVLNKKNKLTQSKIWDVVEKADIGCTPGSG 632
Query: 635 ND 636
D
Sbjct: 633 KD 634
>gi|239752557 PREDICTED: similar to Ovostatin homolog 2 [Homo
sapiens]
Length = 261
Score = 155 bits (391), Expect = 4e-37
Identities = 81/241 (33%), Positives = 134/241 (55%), Gaps = 2/241 (0%)
Query: 381 NKVIFIRGNEANYYSNATTDEHGLVQFSINTTNVMGTSLTVRVNYKDRSPCYGYQWVSEE 440
NK++ + N+ + N TTDE+G QFSI+T+++ ++ Y CY W++ +
Sbjct: 3 NKLLQLELND-EFIGNYTTDENGEAQFSIDTSDIFDPEFNLKATYVRPESCYLPSWLTPQ 61
Query: 441 HEEAHHTAYLVFSPSKSFVHLEPMSHELPCGHTQTVQAHYILNGGTLLGLKKLSFYYLIM 500
+ +AH +S + SF+ + P +L C H + V HY LN + F+YL
Sbjct: 62 YLDAHFLVSRFYSRTNSFLKIVPEPKQLECNHQKVVTVHYSLNSEAYEDDSNVKFFYLCT 121
Query: 501 AKGGIVRTGTHGLLVKQEDMKGHFSISIPVKSDIAPVARLLIYAVLPTGDVIGDSAKYDV 560
+ G + + G+FS + + +D+AP A L +Y + P+G+++ DS ++ V
Sbjct: 122 SDSGNFQHRISSSPIYTA-WNGNFSFPLSISADLAPAAVLFVYTLHPSGEIVADSVRFQV 180
Query: 561 ENCLANKVDLSFSPSQSLPASHAHLRVTAAPQSVCALRAVDQSVLLMKPDAELSASSVYN 620
+ C +KV++ FS Q LP S+A L + AAP CALRAVD++VLL+K + +LSA SV +
Sbjct: 181 DKCFKHKVNIKFSNEQGLPGSNASLCLQAAPVLFCALRAVDRNVLLLKSEQQLSAESVSS 240
Query: 621 L 621
L
Sbjct: 241 L 241
>gi|169217711 PREDICTED: similar to Ovostatin homolog 2 [Homo
sapiens]
Length = 278
Score = 148 bits (373), Expect = 4e-35
Identities = 82/205 (40%), Positives = 114/205 (55%), Gaps = 15/205 (7%)
Query: 673 MGLKAFTNSKIRKPKMC----------PQLQQYEMHGP-EGLRVGFYESDVMGRGHARLV 721
MGLK FTN RKP++C P + E +GP + S + G
Sbjct: 1 MGLKVFTNLHYRKPEVCVMERRLPLPKPLYLETENYGPMRSVPSRIASSGIRGENAD--- 57
Query: 722 HVEEPHTETVRKYFPETWIWDLVVVNSAGVAEVGVTVPDTITEWKAGAFCLSEDAGLGIS 781
+VE+ +TVR FPETW+WDLV V+S+G A + +PDTIT+W+A FC++ D G GIS
Sbjct: 58 YVEQAIIQTVRTNFPETWMWDLVSVDSSGSANLSFLIPDTITQWEASGFCVNGDVGFGIS 117
Query: 782 STASLRAFQPFFVELTMPYSVIRGEAFTLKATVLNYLPKCIRVSVQLEASPAFLA-VPVE 840
ST +L QPFF+E+ P+SV++ E F L V +Y C+ +SVQ+E S + A +
Sbjct: 118 STTTLEVSQPFFIEIASPFSVVQNEQFDLIVNVFSYRNTCVEISVQVEESQNYEANINTW 177
Query: 841 KEQAPHCICANGRQTVSWAVTPKSL 865
K I A GR+T W + PK L
Sbjct: 178 KINGSEVIQAGGRKTNIWTIIPKKL 202
>gi|239755748 PREDICTED: ovostatin [Homo sapiens]
Length = 257
Score = 143 bits (361), Expect = 1e-33
Identities = 74/201 (36%), Positives = 126/201 (62%), Gaps = 7/201 (3%)
Query: 1270 TRTGKAAQVTIQSSGTFSSK--FQVDNNNRLLLQQVSLPELPGEYSMKVTGEGCVYLQTS 1327
++ GK +++ +S + S FQV+ +NRLL+Q+ + + PG+Y++ V G GC ++Q +
Sbjct: 58 SQRGKRGWLSVSASRSEGSSEIFQVNGHNRLLVQRSEVTQAPGQYTVDVEGHGCTFIQAT 117
Query: 1328 LKYNILPEKEEFPFALGVQTLPQTCDEPKAHTSFQISLSVSYTGSRSASNMAIVDVKMVS 1387
LKYN+L K+ F+L ++ + + T+F +++++ YTG R+ S+M ++DVKM+S
Sbjct: 118 LKYNVLLPKKASGFSLSLEIVKNY-----SSTAFDLTVTLKYTGIRNKSSMVVIDVKMLS 172
Query: 1388 GFIPLKPTVKMLERSNHVSRTEVSSNHVLIYLDKVSNQTLSLFFTVLQDVPVRDLKPAIV 1447
GF P +++ LE V +TEV ++HVL YL+ + S F+V Q V +++PA
Sbjct: 173 GFTPTMSSIEELENKGQVMKTEVKNDHVLFYLENGFGRADSFPFSVEQSNLVFNIQPAPA 232
Query: 1448 KVYDYYETDEFAIAEYNAPCS 1468
VYDYYE +E+A+A YN S
Sbjct: 233 MVYDYYEKEEYALAFYNIDSS 253
>gi|239758130 PREDICTED: similar to complement component 4B (Childo
blood group), partial [Homo sapiens]
Length = 666
Score = 131 bits (330), Expect = 4e-30
Identities = 139/514 (27%), Positives = 214/514 (41%), Gaps = 98/514 (19%)
Query: 1042 TAFVLKTFAQARAYIFIDEAHITQALIWLSQRQKDNGCFRSSGSLLNNAIKGGV---EDE 1098
TAFVLK + A+ + + + WL +Q+ +G F+ +++ +++GG+ ++
Sbjct: 1 TAFVLKVLSLAQEQVGGSREKLQETSNWLLSQQQADGSFQDLSPVIHRSMQGGLVGNDET 60
Query: 1099 VTLSAYITIALLEIPLTV-----THPVVRNALFCLESA----WKTAQEGDHGSHVYTKAL 1149
V L+A++TIAL L V P+ + + A + A G G+H A+
Sbjct: 61 VALTAFVTIALHH-GLAVFQDEGAEPLKQRVEASISKANSFLGEKASAGLLGAHA--AAI 117
Query: 1150 LAYAFALA-GNQDKRKEVLKSLNEEAVKKDNSVHW--------------ERPQKPKAPVG 1194
AYA L D R +L A + ++++W P+ P P+
Sbjct: 118 TAYALTLTKAPADLRGVAHNNLMAMAQETGDNLYWGSVTGSQSNAVSPTPAPRNPSDPM- 176
Query: 1195 HFYEPQAPSAEVEMTSYVLLAYLTAQPAPTSEDLTSATNIVKWITKQQNAQGGFSSTQDT 1254
PQAP+ +E T+Y LL L + D +A W+T+Q + QGGF STQDT
Sbjct: 177 ----PQAPALWIETTAYALLHLLLHEGKAEMADQAAA-----WLTRQGSFQGGFRSTQDT 227
Query: 1255 VVALHALSKYGAATFTRTGKAAQVTIQSSGTFSSK---FQVDNNNRLLLQQVSLPELPGE 1311
V+AL ALS Y A+ T + VT+ S+G K Q++N L++ L +
Sbjct: 228 VIALDALSAYWIASHTTEERGLNVTLSSTGRNGFKSHALQLNNRQIRGLEEELQFSLGSK 287
Query: 1312 YSMKVTGEGCVYLQTSLKYNILPEKEEFPFALGVQT-----------------------L 1348
++KV G L+ YN+L K L ++ L
Sbjct: 288 INVKVGGNSKGTLKVLRTYNVLDMKNTTCQDLQIEVTVKGHVEYTMEANEDYEDYEYDEL 347
Query: 1349 PQTCDEPKAH----TSFQI-------------------SLSVSYT------GSRSASNMA 1379
P D+P A T Q+ V YT G S MA
Sbjct: 348 PAK-DDPDAPLQPVTPLQLFEGRRNRRRREAPKVVEEQESRVHYTVCIWRNGKVGLSGMA 406
Query: 1380 IVDVKMVSGFIPLKPTVKMLE--RSNHVSRTEVSSNHVLIYLDKVSNQTLSLFFTVLQDV 1437
I DV ++SGF L+ ++ L +VS E HVL+Y D V + F +Q+V
Sbjct: 407 IADVTLLSGFHALRADLEKLTSLSDRYVSHFETEGPHVLLYFDSVPTSRECVGFEAVQEV 466
Query: 1438 PVRDLKPAIVKVYDYYETDEFAIAEYNAPCSKDL 1471
PV ++PA +YDYY + Y AP L
Sbjct: 467 PVGLVQPASATLYDYYNPERRCSVFYGAPSKSRL 500
>gi|169217713 PREDICTED: similar to Ovostatin homolog 2 [Homo sapiens]
Length = 189
Score = 108 bits (271), Expect = 3e-23
Identities = 60/140 (42%), Positives = 89/140 (63%), Gaps = 9/140 (6%)
Query: 1119 PVVRNALFCLESAWKTAQEGDHGSHVYTKALLAYAFALAGNQDKRKEVLKSLNEEAVKKD 1178
P +RNALFCLE+A + ++ Y A+LAYAFALAG + + + +L++L++ A K +
Sbjct: 48 PALRNALFCLEAALDSGV-----TNGYNHAILAYAFALAGKEKQVESLLQTLDQSATKLN 102
Query: 1179 NSVHWERPQKPKAPVGHFYEPQAPSAEVEMTSYVLLAYLTAQPAPTSEDLTSATNIVKWI 1238
N ++WER +KPK + P APSA+ E + YVLLA ++ + DLT A+ IV+W+
Sbjct: 103 NVIYWERERKPKTEEFPSFIPWAPSAQTEKSCYVLLAVISRK----IPDLTYASKIVQWL 158
Query: 1239 TKQQNAQGGFSSTQDTVVAL 1258
+Q N+ GGFSS Q V L
Sbjct: 159 AQQMNSHGGFSSNQVINVGL 178
>gi|239752555 PREDICTED: similar to Ovostatin homolog 2 [Homo
sapiens]
Length = 195
Score = 105 bits (263), Expect = 2e-22
Identities = 53/188 (28%), Positives = 96/188 (51%), Gaps = 2/188 (1%)
Query: 381 NKVIFIRGNEANYYSNATTDEHGLVQFSINTTNVMGTSLTVRVNYKDRSPCYGYQWVSEE 440
NK++ + N+ + N TTDE+G QFSI+T+++ ++ Y CY W++ +
Sbjct: 3 NKLLQLELND-EFIGNYTTDENGEAQFSIDTSDIFDPEFNLKATYVRPESCYLPSWLTPQ 61
Query: 441 HEEAHHTAYLVFSPSKSFVHLEPMSHELPCGHTQTVQAHYILNGGTLLGLKKLSFYYLIM 500
+ +AH +S + SF+ + P +L C H + V HY LN + F+YL
Sbjct: 62 YLDAHFLVSRFYSRTNSFLKIVPEPKQLECNHQKVVTVHYSLNSEAYEDDSNVKFFYLCT 121
Query: 501 AKGGIVRTGTHGLLVKQEDMKGHFSISIPVKSDIAPVARLLIYAVLPTGDVIGDSAKYDV 560
+ G + + G+FS + + +D+AP A L +Y + P+G+++ DS ++ V
Sbjct: 122 SDSGNFQHRISSSPI-YTAWNGNFSFPLSISADLAPAAVLFVYTLHPSGEIVADSVRFQV 180
Query: 561 ENCLANKV 568
+ C +KV
Sbjct: 181 DKCFKHKV 188
>gi|169205183 PREDICTED: similar to hCG38149 [Homo sapiens]
Length = 95
Score = 77.8 bits (190), Expect = 7e-14
Identities = 39/91 (42%), Positives = 57/91 (62%)
Query: 1378 MAIVDVKMVSGFIPLKPTVKMLERSNHVSRTEVSSNHVLIYLDKVSNQTLSLFFTVLQDV 1437
M ++DVKM+SGF P +++ LE V +TEV ++HVL YL+ + S F+V Q
Sbjct: 1 MVVIDVKMLSGFTPTMSSIEELENKGQVMKTEVKNDHVLFYLENGFGRADSFPFSVEQSN 60
Query: 1438 PVRDLKPAIVKVYDYYETDEFAIAEYNAPCS 1468
V +++PA VYDYYE +E+A+A YN S
Sbjct: 61 LVFNIQPAPAMVYDYYEKEEYALAFYNIDSS 91
>gi|239744557 PREDICTED: hypothetical protein LOC728715 [Homo sapiens]
Length = 95
Score = 77.8 bits (190), Expect = 7e-14
Identities = 39/91 (42%), Positives = 57/91 (62%)
Query: 1378 MAIVDVKMVSGFIPLKPTVKMLERSNHVSRTEVSSNHVLIYLDKVSNQTLSLFFTVLQDV 1437
M ++DVKM+SGF P +++ LE V +TEV ++HVL YL+ + S F+V Q
Sbjct: 1 MVVIDVKMLSGFTPTMSSIEELENKGQVMKTEVKNDHVLFYLENGFGRADSFPFSVEQSN 60
Query: 1438 PVRDLKPAIVKVYDYYETDEFAIAEYNAPCS 1468
V +++PA VYDYYE +E+A+A YN S
Sbjct: 61 LVFNIQPAPAMVYDYYEKEEYALAFYNIDSS 91
>gi|239754277 PREDICTED: similar to Complement component 4A (Rodgers
blood group) [Homo sapiens]
Length = 270
Score = 73.6 bits (179), Expect = 1e-12
Identities = 47/141 (33%), Positives = 79/141 (56%), Gaps = 10/141 (7%)
Query: 129 VFVQTDKSIYKPGQTVKFRVVSMDENFHPLNELIPLVYIQDPKGNRIAQWQSFQLEGGLK 188
+F+QTD+ IY PGQ V++RV ++D+ P + I V +++ G R+ + + + +
Sbjct: 61 LFLQTDQPIYNPGQRVRYRVFALDQKMRPSTDTI-TVMVENSHGLRVRKKEVYMPSSIFQ 119
Query: 189 -QFSFPLSSEPFQGSYKVVVQKKSG--GRTEHPFTVEEFVLPKFEVQVT--VPKIITILE 243
F P SEP G++K+ + G + F V+++VLP FEV++T P I+T+
Sbjct: 120 DDFVIPDISEP--GTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKITPGKPYILTVPG 177
Query: 244 --EEMNVSVCGLYTYGKPVPG 262
+EM + + Y YGKPV G
Sbjct: 178 HLDEMQLDIQARYIYGKPVQG 198
>gi|169217831 PREDICTED: similar to Ovostatin homolog 2 [Homo
sapiens]
Length = 136
Score = 72.4 bits (176), Expect = 3e-12
Identities = 35/119 (29%), Positives = 61/119 (51%), Gaps = 1/119 (0%)
Query: 381 NKVIFIRGNEANYYSNATTDEHGLVQFSINTTNVMGTSLTVRVNYKDRSPCYGYQWVSEE 440
NK++ + N+ + N TTDE+G QFSI+T+++ ++ Y CY W++ +
Sbjct: 3 NKLLQLELND-EFIGNYTTDENGEAQFSIDTSDIFDPEFNLKATYVRPESCYLPSWLTPQ 61
Query: 441 HEEAHHTAYLVFSPSKSFVHLEPMSHELPCGHTQTVQAHYILNGGTLLGLKKLSFYYLI 499
+ +AH +S + SF+ + P +L C H + V HY LN + F+YL+
Sbjct: 62 YLDAHFLVSRFYSRTNSFLKIVPEPKQLECNHQKVVTVHYSLNSEAYEDDSNVKFFYLV 120
>gi|239755754 PREDICTED: ovostatin 2 [Homo sapiens]
Length = 164
Score = 57.8 bits (138), Expect = 8e-08
Identities = 32/84 (38%), Positives = 46/84 (54%)
Query: 1385 MVSGFIPLKPTVKMLERSNHVSRTEVSSNHVLIYLDKVSNQTLSLFFTVLQDVPVRDLKP 1444
++S P LE V +TEV ++HVL YL+ + S F+V Q V +++P
Sbjct: 77 LISILYPSLTISSKLENKGQVMKTEVKNDHVLFYLENGFGRADSFPFSVEQSNLVFNIQP 136
Query: 1445 AIVKVYDYYETDEFAIAEYNAPCS 1468
A VYDYYE +E+A+A YN S
Sbjct: 137 APAMVYDYYEKEEYALAFYNIDSS 160
>gi|169214179 PREDICTED: similar to complement component 3 [Homo
sapiens]
Length = 390
Score = 56.2 bits (134), Expect = 2e-07
Identities = 41/136 (30%), Positives = 70/136 (51%), Gaps = 10/136 (7%)
Query: 1338 EFPFALGVQTLPQTCDEPK-AHTSFQISLSVSYTGSRSASNMAIVDVKMVSGFIPLKPTV 1396
+F + ++ P+T P+ A + + + Y G + A+ M+I+D+ M++GF P +
Sbjct: 87 KFDLKVTIKPAPETEKRPQDAKNTMILEICTRYRGDQDAT-MSILDISMMTGFAPDTDDL 145
Query: 1397 KMLERS--NHVSRTEVSS-----NHVLIYLDKVSN-QTLSLFFTVLQDVPVRDLKPAIVK 1448
K L ++S+ E+ N ++IYLDKVS+ + L F V Q V ++P VK
Sbjct: 146 KQLANGVDRYISKYELDKAFSDRNTLIIYLDKVSHSEDDCLAFKVHQYFNVELIQPGAVK 205
Query: 1449 VYDYYETDEFAIAEYN 1464
VY YY +E Y+
Sbjct: 206 VYAYYNLEESCTRFYH 221
>gi|55749678 ninein-like [Homo sapiens]
Length = 1382
Score = 34.3 bits (77), Expect = 0.91
Identities = 30/109 (27%), Positives = 46/109 (42%), Gaps = 7/109 (6%)
Query: 877 LESQELCGTEVPSVPEHGRKDTVIKPLLVEPEGLEKETTFNSLLCPSGGEVSEELSLKLP 936
LE +E +P + + + + L ++P EK +C S EEL L
Sbjct: 759 LELEEPPQGPLPRGSQRSEQLELERALKLQPCASEKRAQ----MCVSLALEEEELELARG 814
Query: 937 PNVVEESARASVSVL---GDILGSAMQNTQNLLQMPYGCGEQNMVLFAP 982
V S A + L G + GS + T+ LL + GCGE+ + AP
Sbjct: 815 KRVDGPSLEAEMQALPKDGLVAGSGQEGTRGLLPLRPGCGERPLAWLAP 863
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.132 0.385
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 55,431,319
Number of Sequences: 37866
Number of extensions: 2505949
Number of successful extensions: 5671
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 5420
Number of HSP's gapped (non-prelim): 66
length of query: 1474
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1359
effective length of database: 13,892,928
effective search space: 18880489152
effective search space used: 18880489152
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.