Guide to the Human Genome
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Name: A2M Sequence: fasta or formatted (1474aa) NCBI GI: 66932947
Description:

alpha-2-macroglobulin precursor

Referenced in:

Epidermal Growth Factor
Protease Inhibitors

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.3         93           2
 C cysteine            1.7         25           1
 D aspartate           3.7         54           2
 E glutamate           7.1        104           3
 F phenylalanine       4.2         62           2
 G glycine             6.2         91           2
 H histidine           2.7         40           2
 I isoleucine          3.9         57           2
 K lysine              6.0         89           2
 L leucine             9.7        143           4
 M methionine          1.8         26           1
 N asparagine          4.3         63           3
 P proline             5.3         78           2
 Q glutamine           5.0         73           2
 R arginine            3.1         46           1
 S serine              8.3        123           3
 T threonine           6.9        101           2
 V valine              9.4        139           3
 W tryptophan          0.7         11           1
 Y tyrosine            3.8         56           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   alpha-2-macroglobulin precursor 
PZP                   0.715   pregnancy-zone protein 
A2ML1                 0.358   alpha-2-macroglobulin-like 1 
OVOS2                 0.319   PREDICTED: ovostatin 2 
OVOS                  0.304   PREDICTED: ovostatin 
CD109                 0.167   CD109 antigen isoform 1 precursor 
CD109                 0.160   CD109 antigen isoform 2 precursor 
CD109                 0.150   CD109 antigen isoform 3 precursor 
LOC100133592          0.146   PREDICTED: similar to ovostatin-2 
CPAMD8                0.099   C3 and PZP-like, alpha-2-macroglobulin domain conta...
C4B                   0.094   complement component 4B preproprotein 
C4A                   0.093   complement component 4A preproprotein 
LOC100294156          0.093   PREDICTED: similar to C4A protein isoform 1 
LOC100294156          0.091   PREDICTED: similar to C4A protein isoform 2 
C5                    0.083   complement component 5 preproprotein 
C3                    0.065   complement component 3 precursor 
LOC100133511          0.050   PREDICTED: similar to complement component C3, part...
LOC732434             0.044   PREDICTED: similar to Ovostatin homolog 2 
LOC728735             0.042   PREDICTED: similar to Ovostatin homolog 2 
OVOS                  0.040   PREDICTED: ovostatin 
LOC100293534          0.036   PREDICTED: similar to complement component 4B (Chil...
LOC100134413          0.028   PREDICTED: similar to Ovostatin homolog 2 
LOC732435             0.027   PREDICTED: similar to Ovostatin homolog 2 
LOC728715             0.018   PREDICTED: similar to hCG38149 
LOC728715             0.018   PREDICTED: hypothetical protein LOC728715 
LOC100292046          0.017   PREDICTED: similar to Complement component 4A (Rodg...
LOC732435             0.016   PREDICTED: similar to Ovostatin homolog 2 
OVOS2                 0.011   PREDICTED: ovostatin 2 
LOC653879             0.011   PREDICTED: similar to complement component 3 
NINL                  0.003   ninein-like 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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