Guide to the Human Genome
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Search of human proteins with 66472922

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|66472922 muscle-related coiled-coil protein [Homo sapiens]
         (364 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|66472922 muscle-related coiled-coil protein [Homo sapiens]         707   0.0  
gi|42734430 polymerase I and transcript release factor [Homo sap...   170   2e-42
gi|4759082 serum deprivation response protein [Homo sapiens]          157   2e-38
gi|47132587 protein kinase C, delta binding protein [Homo sapiens]     83   3e-16
gi|51472437 PREDICTED: golgi autoantigen, golgin subfamily a, 6C...    53   4e-07
gi|94538359 golgi autoantigen, golgin subfamily a, 6B [Homo sapi...    53   5e-07
gi|146133848 golgi autoantigen, golgin subfamily a, 6 [Homo sapi...    52   8e-07
gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo sap...    50   2e-06
gi|109659847 filamin A interacting protein 1-like isoform 3 [Hom...    49   5e-06
gi|109659845 filamin A interacting protein 1-like isoform 1 [Hom...    49   5e-06
gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens]           49   9e-06
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof...    47   2e-05
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo...    47   3e-05
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo...    47   3e-05
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa...    47   4e-05
gi|71061468 centromere protein E [Homo sapiens]                        47   4e-05
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]     46   5e-05
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]             46   5e-05
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo...    46   6e-05
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]            45   1e-04
gi|55770895 ERBB2 interacting protein isoform 7 [Homo sapiens]         45   1e-04
gi|8923909 ERBB2 interacting protein isoform 2 [Homo sapiens]          45   1e-04
gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]           45   1e-04
gi|239745083 PREDICTED: similar to Golgin subfamily A member 8-l...    45   1e-04
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]     44   2e-04
gi|148746195 trichohyalin [Homo sapiens]                               44   2e-04
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof...    44   2e-04
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap...    44   2e-04
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof...    44   2e-04
gi|22758136 MAP7 domain containing 2 [Homo sapiens]                    44   2e-04

>gi|66472922 muscle-related coiled-coil protein [Homo sapiens]
          Length = 364

 Score =  707 bits (1825), Expect = 0.0
 Identities = 364/364 (100%), Positives = 364/364 (100%)

Query: 1   MEHNGSASNADKIHQNRLSSVTEDEDQDAALTIVTVLDKVASIVDSVQASQKRIEERHRE 60
           MEHNGSASNADKIHQNRLSSVTEDEDQDAALTIVTVLDKVASIVDSVQASQKRIEERHRE
Sbjct: 1   MEHNGSASNADKIHQNRLSSVTEDEDQDAALTIVTVLDKVASIVDSVQASQKRIEERHRE 60

Query: 61  MENAIKSVQIDLLKLSQSHSNTGHIINKLFEKTRKVSAHIKDVKARVEKQQIHVKKVEVK 120
           MENAIKSVQIDLLKLSQSHSNTGHIINKLFEKTRKVSAHIKDVKARVEKQQIHVKKVEVK
Sbjct: 61  MENAIKSVQIDLLKLSQSHSNTGHIINKLFEKTRKVSAHIKDVKARVEKQQIHVKKVEVK 120

Query: 121 QEEIMKKNKFRVVIFQEKFRCPTSLSVVKDRNLTENQEEDDDDIFDPPVDLSSDEEYYVE 180
           QEEIMKKNKFRVVIFQEKFRCPTSLSVVKDRNLTENQEEDDDDIFDPPVDLSSDEEYYVE
Sbjct: 121 QEEIMKKNKFRVVIFQEKFRCPTSLSVVKDRNLTENQEEDDDDIFDPPVDLSSDEEYYVE 180

Query: 181 ESRSARLRKSGKEHIDNIKKAFSKENMQKTRQNLDKKVNRIRTRIVTPERRERLRQSGER 240
           ESRSARLRKSGKEHIDNIKKAFSKENMQKTRQNLDKKVNRIRTRIVTPERRERLRQSGER
Sbjct: 181 ESRSARLRKSGKEHIDNIKKAFSKENMQKTRQNLDKKVNRIRTRIVTPERRERLRQSGER 240

Query: 241 LRQSGERLRQSGERFKKSISNAAPSKEAFKMRSLRKGKDRTVAEGEECAREMGVDIIARS 300
           LRQSGERLRQSGERFKKSISNAAPSKEAFKMRSLRKGKDRTVAEGEECAREMGVDIIARS
Sbjct: 241 LRQSGERLRQSGERFKKSISNAAPSKEAFKMRSLRKGKDRTVAEGEECAREMGVDIIARS 300

Query: 301 ESLGPISELYSDELSEPEHEAARPVYPPHEGREIPTPEPLKVTFKSQVKVEDDESLLLDL 360
           ESLGPISELYSDELSEPEHEAARPVYPPHEGREIPTPEPLKVTFKSQVKVEDDESLLLDL
Sbjct: 301 ESLGPISELYSDELSEPEHEAARPVYPPHEGREIPTPEPLKVTFKSQVKVEDDESLLLDL 360

Query: 361 KHSS 364
           KHSS
Sbjct: 361 KHSS 364


>gi|42734430 polymerase I and transcript release factor [Homo
           sapiens]
          Length = 390

 Score =  170 bits (431), Expect = 2e-42
 Identities = 101/308 (32%), Positives = 174/308 (56%), Gaps = 45/308 (14%)

Query: 26  DQDAALTIVTVLDKVASIVDSVQASQKRIEERHREMENAIKSVQIDLLKLSQSHSNTGHI 85
           DQ   + ++++LDK+   VD +Q +Q ++EER  EME A++S+Q +L KL ++H+ T + 
Sbjct: 47  DQVNGVLVLSLLDKIIGAVDQIQLTQAQLEERQAEMEGAVQSIQGELSKLGKAHATTSNT 106

Query: 86  INKLFEKTRKVSAHIKDVKARVEKQQIHVKKVEVKQEEIMKKNKFRVVIFQEKFRCPTSL 145
           ++KL EK RKVS ++K V+  +E+Q   +KK+EV + E++++  F+V+I+Q++ + P  L
Sbjct: 107 VSKLLEKVRKVSVNVKTVRGSLERQAGQIKKLEVNEAELLRRRNFKVMIYQDEVKLPAKL 166

Query: 146 SVVKD------------RNLTENQEEDDDDIFDPPVDLSSDE----EYYVEESRSARLRK 189
           S+ K               L E +  ++D      ++LSSDE    E  +EESR+ R+++
Sbjct: 167 SISKSLKESEALPEKEGEELGEGERPEED---AAALELSSDEAVEVEEVIEESRAERIKR 223

Query: 190 SGKEHIDNIKKAFS----------------------KENMQKTRQNLDKKVNRIRTRIVT 227
           SG   +D+ KKAFS                      KEN++KTR  L+K++N++ TR+V 
Sbjct: 224 SGLRRVDDFKKAFSKEKMEKTKVRTRENLEKTRLKTKENLEKTRHTLEKRMNKLGTRLVP 283

Query: 228 PERRERLRQSGERLRQSGERLRQSGERFKKSISNAAPSKEAFKMRSLRKGKDRTVAEGEE 287
            ERRE+L+ S ++LR+S         R K ++    P    F ++ +R+G+   +   E 
Sbjct: 284 AERREKLKTSRDKLRKSFTPDHVVYARSKTAVYKVPPF--TFHVKKIREGQVEVLKATEM 341

Query: 288 CAREMGVD 295
              E+G D
Sbjct: 342 V--EVGAD 347


>gi|4759082 serum deprivation response protein [Homo sapiens]
          Length = 425

 Score =  157 bits (396), Expect = 2e-38
 Identities = 105/330 (31%), Positives = 186/330 (56%), Gaps = 48/330 (14%)

Query: 6   SASNADKIHQNRLSSVTEDEDQDAALTIVTVLDKVASIVDSVQASQKRIEERHREMENAI 65
           S++ +  ++         D  Q  A+T++T+LDK+ +++D+VQ +Q ++E+R   +E ++
Sbjct: 31  SSTPSPSLNLGNTEEAIRDNSQVNAVTVLTLLDKLVNMLDAVQENQHKMEQRQISLEGSV 90

Query: 66  KSVQIDLLKLSQSHSNTGHIINKLFEKTRKVSAHIKDVKARVEKQQIHVKKVEVKQEEIM 125
           K +Q DL KLS+  ++T + ++KL EK+RKVSAH + VK R+++Q   VK++E    +++
Sbjct: 91  KGIQNDLTKLSKYQASTSNTVSKLLEKSRKVSAHTRAVKERMDRQCAQVKRLENNHAQLL 150

Query: 126 KKNKFRVVIFQEKFRCPTSLSVVKD-RNLTENQEE--DDDDIFDP---PVDLSSDE---- 175
           ++N F+V+IFQE+   P S+ V +      E +EE  D++   +     VDLSSD+    
Sbjct: 151 RRNHFKVLIFQEENEIPASVFVKQPVSGAVEGKEELPDENKSLEETLHTVDLSSDDDLPH 210

Query: 176 ---------EYYVEESRSARLRKSGKEHIDNIKKAFSKENMQKTRQNLDKKVNRIRTRIV 226
                    E  VEESR+ ++++S  + +D++KKAFS       RQN++KK+N++ T+IV
Sbjct: 211 DEEALEDSAEEKVEESRAEKIKRSSLKKVDSLKKAFS-------RQNIEKKMNKLGTKIV 263

Query: 227 TPERRERLRQSGERLRQSGERLRQSGERFKKSISNAAPSKEAFKMRSLRKGKDRTVAEGE 286
           + ERRE++++S             +    K S   ++P    FK+  L  G+ + V EGE
Sbjct: 264 SVERREKIKKS------------LTSNHQKISSGKSSP----FKVSPLTFGR-KKVREGE 306

Query: 287 ECAREMGVDIIARSESLGPISELYSDELSE 316
             A         +SE L    ++ +D+  E
Sbjct: 307 SHAENE-----TKSEDLPSSEQMPNDQEEE 331


>gi|47132587 protein kinase C, delta binding protein [Homo sapiens]
          Length = 261

 Score = 83.2 bits (204), Expect = 3e-16
 Identities = 49/175 (28%), Positives = 97/175 (55%), Gaps = 3/175 (1%)

Query: 30  ALTIVTVLDKVASIVDSVQASQKRIEERHREMENAIKSVQIDLLKLSQSHSNTGHIINKL 89
           A+T+VT+L+K+AS++++++  Q  +  R   +  +++ +Q  L  LS+SH  T + + +L
Sbjct: 22  AVTVVTLLEKLASMLETLRERQGGLARRQGGLAGSVRRIQSGLGALSRSHDTTSNTLAQL 81

Query: 90  FEKTRKVSAHIKDVKARVEKQQIHVKKVEVKQEEIMKKNKFRVVIFQEKFRCPTSLSVVK 149
             K  +VS+H    + R  ++   V+++E     ++ + K  V++F+E+   P S     
Sbjct: 82  LAKAERVSSHANAAQERAVRRAAQVQRLEANHGLLVARGKLHVLLFKEEGEVPASAFQKA 141

Query: 150 DRNL-TENQEEDDDDIFDPPVDLSSDEEYYVEESRSARLRKSGKEHIDNIKKAFS 203
              L   +Q E   +  +  V  SSDEE    ESR+ RLR++G + + ++++A S
Sbjct: 142 PEPLGPADQSELGPEQLEAEVGESSDEE--PVESRAQRLRRTGLQKVQSLRRALS 194


>gi|51472437 PREDICTED: golgi autoantigen, golgin subfamily a, 6C
           isoform 1 [Homo sapiens]
          Length = 693

 Score = 53.1 bits (126), Expect = 4e-07
 Identities = 54/244 (22%), Positives = 110/244 (45%), Gaps = 26/244 (10%)

Query: 56  ERHREMENAIKSVQIDLLKLSQSHSNTGHIINKLFEKTRK----VSAHIKDVKARVEKQQ 111
           +R +E+E A+ +V     +  +S S    ++ +  ++T K    ++AH+  V   +++ Q
Sbjct: 167 QRIQELERALSAVSTQQQEEDRSSSCREAVLQRRLQQTIKERALLNAHVTQVTESLKQVQ 226

Query: 112 I-------HVKKVEVKQEEIMKKNKFRVVIFQEKFRCPTSLSVVKDRNLTE--NQEEDDD 162
           +       H+K    + +E M K        +E+ +         +R+L+E  NQ  +  
Sbjct: 227 LERDEYAKHIKGERARWQERMWKMSVEARTLKEEKKRDIHRIQELERSLSELKNQMAEPP 286

Query: 163 DIFDPPVDLSSDEEYYVEESRSARLRKSGKE-----HIDNIK--KAFSKENMQKTRQN-- 213
            +  P V  +S  E   +E++  R    G E      ++N +     SKE  Q+ ++   
Sbjct: 287 SLAPPAV--TSVVEQLQDEAKHLRQEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEE 344

Query: 214 --LDKKVNRIRTRIVTPERRERLRQSGERLRQSGERLRQSGERFKKSISNAAPSKEAFKM 271
              +++  R+R +    E+ ERLR+  + L++ GERLR+  +R +K        +E  + 
Sbjct: 345 MLREQEAQRVREQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQK 404

Query: 272 RSLR 275
           +  R
Sbjct: 405 QEKR 408



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 65/341 (19%), Positives = 142/341 (41%), Gaps = 34/341 (9%)

Query: 14  HQNRLSSVTEDEDQDAALTIVTVLDKVASIVDSVQA--SQKRIEERHREMENAI--KSVQ 69
           H  R +   E+E +D A  +   L ++  +  ++ A  +Q++ E+R      A+  + +Q
Sbjct: 143 HTKRAARHFEEESKDLAGRLQYSLQRIQELERALSAVSTQQQEEDRSSSCREAVLQRRLQ 202

Query: 70  IDLLKLSQSHSNTGHIINKLFEKTRKVSAHIKDVKARVEKQQIHVKKVEVKQEEIMKKNK 129
             + + +  +++   +   L +   +   + K +K    + Q  + K+ V+   + ++ K
Sbjct: 203 QTIKERALLNAHVTQVTESLKQVQLERDEYAKHIKGERARWQERMWKMSVEARTLKEEKK 262

Query: 130 FRVVIFQEKFRC----------PTSLSVVKDRNLTENQEEDDDDIFDPPVDLSSDEEYYV 179
             +   QE  R           P SL+     ++ E  +++   +      L    +  V
Sbjct: 263 RDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVEQLQDEAKHLRQEVEGLEGKLQSQV 322

Query: 180 EESRS-ARLRKSGKEHIDNIKKAFSKENMQKTRQN--LDKKVNRIRT----------RIV 226
           E +++ + L K  K+ +   ++   ++  Q+ R+   L ++  R+R           R+ 
Sbjct: 323 ENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQGERLR 382

Query: 227 TPERR-----ERLRQSGERLRQSGERLRQSGERFKKSISNAAPSKEAFKMRSLRKGKDRT 281
             E+R     ERLR+  ERL++  +RL    ER  K        +E   +    K  D+ 
Sbjct: 383 KQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHK-LDKQ 441

Query: 282 VAEGEECAREMGVDIIARSESLGPISELYSDELSEPEHEAA 322
           +AE +    ++  +  +  +    + EL  ++L E   EAA
Sbjct: 442 LAEPQCSFEDLNNEKKSALQLEQQVKEL-QEKLDEEHLEAA 481


>gi|94538359 golgi autoantigen, golgin subfamily a, 6B [Homo
           sapiens]
          Length = 693

 Score = 52.8 bits (125), Expect = 5e-07
 Identities = 55/244 (22%), Positives = 111/244 (45%), Gaps = 26/244 (10%)

Query: 56  ERHREMENAIKSVQIDLLKLSQSHSNTGHIINKLFEKTRK----VSAHIKDVKARVEKQQ 111
           +R +E+E A+ +V     +  +S S    ++++  ++T K    ++AH+  V   +++ Q
Sbjct: 167 QRIQELERALCAVSTQQQEEDRSSSCREAVLHRRLQQTIKERALLNAHVTQVTESLKQVQ 226

Query: 112 I-------HVKKVEVKQEEIMKKNKFRVVIFQEKFRCPTSLSVVKDRNLTE--NQEEDDD 162
           +       H+K    + +E M K        +E+ +         +R+L+E  NQ     
Sbjct: 227 LERDEYAKHIKGERARWQERMWKMSVEARTLKEEKKRDIHRIQELERSLSELKNQMAKPP 286

Query: 163 DIFDPPVDLSSDEEYYVEESRSARLRKSGKE-----HIDNIK--KAFSKENMQKTRQN-- 213
            +  P V  +S  E   +E++  R    G E      ++N +     SKE  Q+ ++   
Sbjct: 287 SLAPPAV--TSVVEQLQDEAKHLRQEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEE 344

Query: 214 --LDKKVNRIRTRIVTPERRERLRQSGERLRQSGERLRQSGERFKKSISNAAPSKEAFKM 271
              +++V R+R +    E+ ERLR+  + L++ GERLR+  +R +K        +E  + 
Sbjct: 345 MLREQEVQRVREQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQK 404

Query: 272 RSLR 275
           +  R
Sbjct: 405 QEKR 408



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 65/341 (19%), Positives = 143/341 (41%), Gaps = 34/341 (9%)

Query: 14  HQNRLSSVTEDEDQDAALTIVTVLDKVASIVDSVQA--SQKRIEERHREMENAI--KSVQ 69
           H  R +   E+E +D A  +   L ++  +  ++ A  +Q++ E+R      A+  + +Q
Sbjct: 143 HTKRAARHFEEESKDLAGRLQYSLQRIQELERALCAVSTQQQEEDRSSSCREAVLHRRLQ 202

Query: 70  IDLLKLSQSHSNTGHIINKLFEKTRKVSAHIKDVKARVEKQQIHVKKVEVKQEEIMKKNK 129
             + + +  +++   +   L +   +   + K +K    + Q  + K+ V+   + ++ K
Sbjct: 203 QTIKERALLNAHVTQVTESLKQVQLERDEYAKHIKGERARWQERMWKMSVEARTLKEEKK 262

Query: 130 FRVVIFQEKFRC----------PTSLSVVKDRNLTENQEEDDDDIFDPPVDLSSDEEYYV 179
             +   QE  R           P SL+     ++ E  +++   +      L    +  V
Sbjct: 263 RDIHRIQELERSLSELKNQMAKPPSLAPPAVTSVVEQLQDEAKHLRQEVEGLEGKLQSQV 322

Query: 180 EESRS-ARLRKSGKEHIDNIKKAFSKENMQKTRQN--LDKKVNRIRT----------RIV 226
           E +++ + L K  K+ +   ++   ++ +Q+ R+   L ++  R+R           R+ 
Sbjct: 323 ENNQALSLLSKEQKQRLQEQEEMLREQEVQRVREQERLCEQNERLREQQKTLQEQGERLR 382

Query: 227 TPERR-----ERLRQSGERLRQSGERLRQSGERFKKSISNAAPSKEAFKMRSLRKGKDRT 281
             E+R     ERLR+  ERL++  +RL    ER  K        +E   +    K  D+ 
Sbjct: 383 KQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHK-LDKQ 441

Query: 282 VAEGEECAREMGVDIIARSESLGPISELYSDELSEPEHEAA 322
           +AE +    ++  +  +  +    + EL  ++L E   EAA
Sbjct: 442 LAEPQCSFEDLNNEKKSALQLEQQVKEL-QEKLDEEHLEAA 481


>gi|146133848 golgi autoantigen, golgin subfamily a, 6 [Homo
           sapiens]
          Length = 693

 Score = 52.0 bits (123), Expect = 8e-07
 Identities = 54/244 (22%), Positives = 110/244 (45%), Gaps = 26/244 (10%)

Query: 56  ERHREMENAIKSVQIDLLKLSQSHSNTGHIINKLFEKTRK----VSAHIKDVKARVEKQQ 111
           +R +E+E A+ +V     +  +S S    ++ +  ++T K    ++AH+  V   +++ Q
Sbjct: 167 QRIQELERALCAVSTQQQEEDRSSSCREAVLQRWLQQTIKERALLNAHVTQVTESLKQVQ 226

Query: 112 I-------HVKKVEVKQEEIMKKNKFRVVIFQEKFRCPTSLSVVKDRNLTE--NQEEDDD 162
           +       H+K    + +E M K        +E+ +         +R+L+E  NQ  +  
Sbjct: 227 LERDEYAKHIKGERARWQERMWKMSVEARTLKEEKKRDIHRIQELERSLSELKNQMAEPP 286

Query: 163 DIFDPPVDLSSDEEYYVEESRSARLRKSGKE-----HIDNIK--KAFSKENMQKTRQN-- 213
            +  P V  +S  E   +E++  R    G E      ++N +     SKE  Q+ ++   
Sbjct: 287 SLAPPAV--TSVVEQLQDEAKHLRQEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEE 344

Query: 214 --LDKKVNRIRTRIVTPERRERLRQSGERLRQSGERLRQSGERFKKSISNAAPSKEAFKM 271
              +++  R+R +    E+ ERLR+  + L++ GERLR+  +R +K        +E  + 
Sbjct: 345 MLREQEAQRVREQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQK 404

Query: 272 RSLR 275
           +  R
Sbjct: 405 QEKR 408



 Score = 38.5 bits (88), Expect = 0.010
 Identities = 67/355 (18%), Positives = 148/355 (41%), Gaps = 39/355 (10%)

Query: 14  HQNRLSSVTEDEDQDAALTIVTVLDKVASIVDSVQA--SQKRIEERHREMENAI--KSVQ 69
           H  R +   E+E +D A  +   L ++  +  ++ A  +Q++ E+R      A+  + +Q
Sbjct: 143 HTKRAARHFEEESKDLAGRLQYSLQRIQELERALCAVSTQQQEEDRSSSCREAVLQRWLQ 202

Query: 70  IDLLKLSQSHSNTGHIINKLFEKTRKVSAHIKDVKARVEKQQIHVKKVEVKQEEIMKKNK 129
             + + +  +++   +   L +   +   + K +K    + Q  + K+ V+   + ++ K
Sbjct: 203 QTIKERALLNAHVTQVTESLKQVQLERDEYAKHIKGERARWQERMWKMSVEARTLKEEKK 262

Query: 130 FRVVIFQEKFRC----------PTSLSVVKDRNLTENQEEDDDDIFDPPVDLSSDEEYYV 179
             +   QE  R           P SL+     ++ E  +++   +      L    +  V
Sbjct: 263 RDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVEQLQDEAKHLRQEVEGLEGKLQSQV 322

Query: 180 EESRS-ARLRKSGKEHIDNIKKAFSKENMQKTRQN--LDKKVNRIRT----------RIV 226
           E +++ + L K  K+ +   ++   ++  Q+ R+   L ++  R+R           R+ 
Sbjct: 323 ENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQGERLR 382

Query: 227 TPERR-----ERLRQSGERLRQSGERLRQSGERFKKSISNAAPSKEAFKMRSLRKGKDRT 281
             E+R     ERLR+  ERL++  +RL    ER  K        +E   +    K  D+ 
Sbjct: 383 KQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHK-LDKQ 441

Query: 282 VAEGEECAREMGVDIIARSESLGPISELYSDELSEPEHEAARPVYPPHEGREIPT 336
           +AE +    ++  +  +  +    + EL  ++L E   EAA      H+ +++ T
Sbjct: 442 LAEPQCSFEDLNNEKKSALQLEQQVKEL-QEKLDEEHLEAA-----SHQNQQLET 490


>gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo
           sapiens]
          Length = 693

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 53/241 (21%), Positives = 108/241 (44%), Gaps = 26/241 (10%)

Query: 59  REMENAIKSVQIDLLKLSQSHSNTGHIINKLFEKTRK----VSAHIKDVKARVEKQQI-- 112
           +E+E A+ +V     +  +S S    ++ +  ++T K    ++AH+  V   +++ Q+  
Sbjct: 170 QELERALCAVSTQQQEEDRSSSCREAVLQRRLQQTIKERALLNAHVTQVTESLKQVQLER 229

Query: 113 -----HVKKVEVKQEEIMKKNKFRVVIFQEKFRCPTSLSVVKDRNLTE--NQEEDDDDIF 165
                H+K    + +E M K        +E+ +         +R+L+E  NQ  +   + 
Sbjct: 230 DEYAKHIKGERARWQERMWKMSVEARTLKEEKKRDIHRIQELERSLSELKNQMAEPPSLA 289

Query: 166 DPPVDLSSDEEYYVEESRSARLRKSGKE-----HIDNIK--KAFSKENMQKTRQN----L 214
            P V  +S  E   +E++  R    G E      ++N +     SKE  Q+ ++      
Sbjct: 290 PPAV--TSVVEQLQDEAKHLRQEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLR 347

Query: 215 DKKVNRIRTRIVTPERRERLRQSGERLRQSGERLRQSGERFKKSISNAAPSKEAFKMRSL 274
           +++  R+R +    E+ ERLR+  + L++ GERLR+  +R +K        +E  + +  
Sbjct: 348 EQEAQRVREQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEK 407

Query: 275 R 275
           R
Sbjct: 408 R 408



 Score = 37.4 bits (85), Expect = 0.021
 Identities = 65/341 (19%), Positives = 141/341 (41%), Gaps = 34/341 (9%)

Query: 14  HQNRLSSVTEDEDQDAALTIVTVLDKVASIVDSVQA--SQKRIEERHREMENAI--KSVQ 69
           H  R +   E+E +D A  +   L  +  +  ++ A  +Q++ E+R      A+  + +Q
Sbjct: 143 HTKRAARHFEEESKDLAGRLQYSLQHIQELERALCAVSTQQQEEDRSSSCREAVLQRRLQ 202

Query: 70  IDLLKLSQSHSNTGHIINKLFEKTRKVSAHIKDVKARVEKQQIHVKKVEVKQEEIMKKNK 129
             + + +  +++   +   L +   +   + K +K    + Q  + K+ V+   + ++ K
Sbjct: 203 QTIKERALLNAHVTQVTESLKQVQLERDEYAKHIKGERARWQERMWKMSVEARTLKEEKK 262

Query: 130 FRVVIFQEKFRC----------PTSLSVVKDRNLTENQEEDDDDIFDPPVDLSSDEEYYV 179
             +   QE  R           P SL+     ++ E  +++   +      L    +  V
Sbjct: 263 RDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVEQLQDEAKHLRQEVEGLEGKLQSQV 322

Query: 180 EESRS-ARLRKSGKEHIDNIKKAFSKENMQKTRQN--LDKKVNRIRT----------RIV 226
           E +++ + L K  K+ +   ++   ++  Q+ R+   L ++  R+R           R+ 
Sbjct: 323 ENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQGERLR 382

Query: 227 TPERR-----ERLRQSGERLRQSGERLRQSGERFKKSISNAAPSKEAFKMRSLRKGKDRT 281
             E+R     ERLR+  ERL++  +RL    ER  K        +E   +    K  D+ 
Sbjct: 383 KQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHK-LDKQ 441

Query: 282 VAEGEECAREMGVDIIARSESLGPISELYSDELSEPEHEAA 322
           +AE +    ++  +  +  +    + EL  ++L E   EAA
Sbjct: 442 LAEPQCSFEDLNNEKKSALQLEQQVKEL-QEKLDEEHLEAA 481


>gi|109659847 filamin A interacting protein 1-like isoform 3 [Homo
           sapiens]
          Length = 1133

 Score = 49.3 bits (116), Expect = 5e-06
 Identities = 52/268 (19%), Positives = 121/268 (45%), Gaps = 20/268 (7%)

Query: 37  LDKVASIVDSVQASQKRIEERHREMENAIKSVQIDLLKLSQSHSN----TGHIINKLFEK 92
           ++++  +V+  + S +RI  +    E + +   ++L +  + H      +   I  L ++
Sbjct: 140 MNELDKVVEKHKESYRRILGQLLVAEKSRRQTILELEEEKRKHKEYMEKSDEFICLLEQE 199

Query: 93  TRKVSAHI-KDVKARVEKQQIHVKKVEVKQEEIMKKNKFRVVIFQEKFRCPTSLSVVKDR 151
             ++   I +++K++ EK+Q   K+V   +EE+ K   F +++  E+ R    L++ + +
Sbjct: 200 CERLKKLIDQEIKSQEEKEQEKEKRVTTLKEELTKLKSFALMVVDEQQRLTAQLTLQRQK 259

Query: 152 --NLTENQEEDDDDIFDPPVDLSSDEEYYVEESRSARLRKSGKEHIDNIKKAFSKENMQK 209
              LT N +E    +        ++     EE ++ RL K  +       +   ++ +  
Sbjct: 260 IQELTTNAKETHTKL------ALAEARVQEEEQKATRLEKELQTQTTKFHQ--DQDTIMA 311

Query: 210 TRQNLDKKVNRIRTRIVTPERR-ERLRQSGERLRQSGERLRQSGERFKK-SISNAAPSKE 267
              N D +  +++ ++    R+ + L ++   LR++ E L+   E+  K    NA    E
Sbjct: 312 KLTNEDSQNRQLQQKLAALSRQIDELEETNRSLRKAEEELQDIKEKISKGEYGNAGIMAE 371

Query: 268 AFKMRSL---RKGKDRTVAEGEECAREM 292
             ++R      +GKD  + + EE  R++
Sbjct: 372 VEELRKRVLDMEGKDEELIKMEEQCRDL 399



 Score = 35.4 bits (80), Expect = 0.081
 Identities = 63/310 (20%), Positives = 131/310 (42%), Gaps = 55/310 (17%)

Query: 6   SASNADKIHQNRLSSVTE---DEDQDAALTIVTVLDKVASIV---DSVQASQKRIEERHR 59
           +AS+  ++ QN++++VTE   +E + A  +   V +K+ S+    D ++   K  EE+  
Sbjct: 520 AASSQLQVEQNKVTTVTEKLIEETKRALKSKTDVEEKMYSVTKERDDLKNKLKAEEEKGN 579

Query: 60  EMEN----------AIKSVQIDLLKLSQSHSNTGHIINKLFEKTRKVSAHIKDVKARVEK 109
           ++ +          ++++++ D LK ++ + ++G     L ++  K    IK++   VE+
Sbjct: 580 DLLSRVNMLKNRLQSLEAIEKDFLK-NKLNQDSGKSTTALHQENNK----IKELSQEVER 634

Query: 110 QQIHVKKVEVKQEEIMK------------KNKFRVVIFQEKFRCPTSLSVVKDRNLTENQ 157
            ++ +K ++  ++++MK             N+     F  K      + + K +   + +
Sbjct: 635 LKLKLKDMKAIEDDLMKTEDEYETLERRYANERDKAQFLSKELEHVKMELAKYKLAEKTE 694

Query: 158 EEDDDDIFDPPVDLSSDEEYYVEESRSARLRKSGKEHIDNIKKAFSKE----NMQKTRQN 213
              +  +F         +    EE++S  L +      + I +  + E    ++Q     
Sbjct: 695 TSHEQWLF---------KRLQEEEAKSGHLSREVDALKEKIHEYMATEDLICHLQGDHSV 745

Query: 214 LDKKVNRIRTRIVTPERR-ERLRQSGERLRQSGERLRQS--GER------FKKSISNAAP 264
           L KK+N+   R     R  E L +  ER R   + LR S  G R      F K +   A 
Sbjct: 746 LQKKLNQQENRNRDLGREIENLTKELERYRHFSKSLRPSLNGRRISDPQVFSKEVQTEAV 805

Query: 265 SKEAFKMRSL 274
             E    +SL
Sbjct: 806 DNEPPDYKSL 815


>gi|109659845 filamin A interacting protein 1-like isoform 1 [Homo
           sapiens]
          Length = 1135

 Score = 49.3 bits (116), Expect = 5e-06
 Identities = 52/268 (19%), Positives = 121/268 (45%), Gaps = 20/268 (7%)

Query: 37  LDKVASIVDSVQASQKRIEERHREMENAIKSVQIDLLKLSQSHSN----TGHIINKLFEK 92
           ++++  +V+  + S +RI  +    E + +   ++L +  + H      +   I  L ++
Sbjct: 140 MNELDKVVEKHKESYRRILGQLLVAEKSRRQTILELEEEKRKHKEYMEKSDEFICLLEQE 199

Query: 93  TRKVSAHI-KDVKARVEKQQIHVKKVEVKQEEIMKKNKFRVVIFQEKFRCPTSLSVVKDR 151
             ++   I +++K++ EK+Q   K+V   +EE+ K   F +++  E+ R    L++ + +
Sbjct: 200 CERLKKLIDQEIKSQEEKEQEKEKRVTTLKEELTKLKSFALMVVDEQQRLTAQLTLQRQK 259

Query: 152 --NLTENQEEDDDDIFDPPVDLSSDEEYYVEESRSARLRKSGKEHIDNIKKAFSKENMQK 209
              LT N +E    +        ++     EE ++ RL K  +       +   ++ +  
Sbjct: 260 IQELTTNAKETHTKL------ALAEARVQEEEQKATRLEKELQTQTTKFHQ--DQDTIMA 311

Query: 210 TRQNLDKKVNRIRTRIVTPERR-ERLRQSGERLRQSGERLRQSGERFKK-SISNAAPSKE 267
              N D +  +++ ++    R+ + L ++   LR++ E L+   E+  K    NA    E
Sbjct: 312 KLTNEDSQNRQLQQKLAALSRQIDELEETNRSLRKAEEELQDIKEKISKGEYGNAGIMAE 371

Query: 268 AFKMRSL---RKGKDRTVAEGEECAREM 292
             ++R      +GKD  + + EE  R++
Sbjct: 372 VEELRKRVLDMEGKDEELIKMEEQCRDL 399



 Score = 35.4 bits (80), Expect = 0.081
 Identities = 63/310 (20%), Positives = 131/310 (42%), Gaps = 55/310 (17%)

Query: 6   SASNADKIHQNRLSSVTE---DEDQDAALTIVTVLDKVASIV---DSVQASQKRIEERHR 59
           +AS+  ++ QN++++VTE   +E + A  +   V +K+ S+    D ++   K  EE+  
Sbjct: 520 AASSQLQVEQNKVTTVTEKLIEETKRALKSKTDVEEKMYSVTKERDDLKNKLKAEEEKGN 579

Query: 60  EMEN----------AIKSVQIDLLKLSQSHSNTGHIINKLFEKTRKVSAHIKDVKARVEK 109
           ++ +          ++++++ D LK ++ + ++G     L ++  K    IK++   VE+
Sbjct: 580 DLLSRVNMLKNRLQSLEAIEKDFLK-NKLNQDSGKSTTALHQENNK----IKELSQEVER 634

Query: 110 QQIHVKKVEVKQEEIMK------------KNKFRVVIFQEKFRCPTSLSVVKDRNLTENQ 157
            ++ +K ++  ++++MK             N+     F  K      + + K +   + +
Sbjct: 635 LKLKLKDMKAIEDDLMKTEDEYETLERRYANERDKAQFLSKELEHVKMELAKYKLAEKTE 694

Query: 158 EEDDDDIFDPPVDLSSDEEYYVEESRSARLRKSGKEHIDNIKKAFSKE----NMQKTRQN 213
              +  +F         +    EE++S  L +      + I +  + E    ++Q     
Sbjct: 695 TSHEQWLF---------KRLQEEEAKSGHLSREVDALKEKIHEYMATEDLICHLQGDHSV 745

Query: 214 LDKKVNRIRTRIVTPERR-ERLRQSGERLRQSGERLRQS--GER------FKKSISNAAP 264
           L KK+N+   R     R  E L +  ER R   + LR S  G R      F K +   A 
Sbjct: 746 LQKKLNQQENRNRDLGREIENLTKELERYRHFSKSLRPSLNGRRISDPQVFSKEVQTEAV 805

Query: 265 SKEAFKMRSL 274
             E    +SL
Sbjct: 806 DNEPPDYKSL 815


>gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens]
          Length = 320

 Score = 48.5 bits (114), Expect = 9e-06
 Identities = 38/165 (23%), Positives = 76/165 (46%), Gaps = 13/165 (7%)

Query: 153 LTENQEEDDDDIFDPPVDLSSDEEYYVEESRSARLRKSGKEHIDNIKKAFSKENMQKTRQ 212
           L E+++EDD D+    +D S +E+   ++S      KS   H  +  ++ S  + +   +
Sbjct: 169 LDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSR 228

Query: 213 NLDKKVNRIRTRIVTPERRERLRQSGERLRQSGERLRQSGERFKKSISNAAPSKEAFKMR 272
           +  +  +  ++R  +  R ER R  G + R S    R S    K+S S+++ S E    R
Sbjct: 229 SRSRSSSSSQSRSRSSSR-ERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPE----R 283

Query: 273 SLRKGKDRTVAEGEECAREMGVDIIARSESLGPISELYSDELSEP 317
           + ++ + R+ + G+   R        R+ S  P S++  +   +P
Sbjct: 284 NRKRSRSRSSSSGDRKKR--------RTRSRSPESQVIGENTKQP 320


>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           2 [Homo sapiens]
          Length = 782

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 55/249 (22%), Positives = 103/249 (41%), Gaps = 23/249 (9%)

Query: 89  LFEKTRKVSAHIKDVKARVEKQQIHVKKVEVKQEEIMKKNKFRVVIFQEKFRCPTSLSVV 148
           L EK R+     K    R++       K +  +E  ++ ++  + I    +R        
Sbjct: 17  LQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYR-------- 68

Query: 149 KDRNLTENQEEDDDDIFDPPVDLSSDEEYY---VEESRSARLRKSGKEHIDNIKKAFSKE 205
           ++ ++ +  EEDD     PP  +S  E+ +    E+ +  R  +S         +   KE
Sbjct: 69  REDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKRRHRSHSAEGGKHARVKEKE 128

Query: 206 NMQKTRQNLDKKVNRIRTRIVTPERRERLRQSGERLRQSGERLRQSGERFKKSISNAAPS 265
              + R+   ++ ++ R      +RRE  R+   R R   E+L +  ER +K        
Sbjct: 129 REHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERK-------M 181

Query: 266 KEAFKMRSLRKGKDRTVAEGEECAREMGVDIIARSESLGPISELYSDELSEPEHEAARPV 325
           +E  K +  +K ++R  AE     RE   ++ A   ++    E YSD++ +  H +  P 
Sbjct: 182 REQQKEQREQKERERR-AEERRKEREARREVSAHHRTM---REDYSDKV-KASHWSRSPP 236

Query: 326 YPPHEGREI 334
            PP E  E+
Sbjct: 237 RPPRERFEL 245


>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
            sapiens]
          Length = 1941

 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 68/335 (20%), Positives = 137/335 (40%), Gaps = 58/335 (17%)

Query: 14   HQNRLSSVTEDEDQDAALTIVTVLDKVASIVDSVQASQKRIEERHREMENAIKSVQIDLL 73
            HQ  L  +  +ED+   LT   +  K+   VD ++ S ++ ++   ++E A + ++ DL 
Sbjct: 1009 HQQTLDDLQAEEDKVNTLTKAKI--KLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLK 1066

Query: 74   KLSQSHSNTGHIINKLFEKTRKVSAHIKDVKARVEKQQI-------HVKKVEVK----QE 122
               +S  +  +   +L EK +K    I ++++++E +Q         +K+++ +    +E
Sbjct: 1067 LAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEE 1126

Query: 123  EIMKKNKFRVVIFQEKFRCPTSLSVVKDR---------NLTENQEEDDDDIFDPPVDLSS 173
            EI  +   R    +++      L  + +R            E  ++ + +      DL  
Sbjct: 1127 EIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDL-- 1184

Query: 174  DEEYYVEESRSARLRKSGK-------EHIDNIKKAFSK-------------------ENM 207
            +E     E+ +A LRK          E IDN+++   K                   E +
Sbjct: 1185 EEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETV 1244

Query: 208  QKTRQNLDKKVNRIRTRI--VTPERRERLRQSGERLRQSGERLRQSGERFKKSISNAAPS 265
             K + NL+K    +  ++  +  +  E+ R   +   Q G    +SGE      S     
Sbjct: 1245 SKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGE-----FSRQLDE 1299

Query: 266  KEAFKMRSLRKGKDRTVAEGEECAREMGVDIIARS 300
            KEA  +  L +GK     + EE  R++  +I A++
Sbjct: 1300 KEAL-VSQLSRGKQAFTQQIEELKRQLEEEIKAKN 1333



 Score = 32.7 bits (73), Expect = 0.52
 Identities = 55/295 (18%), Positives = 135/295 (45%), Gaps = 24/295 (8%)

Query: 33   IVTVLDKVASIVDSVQASQKRIEERHREMENAIKS---VQIDLLKLSQSHSNTGHIINKL 89
            +VT+L +   +   VQA  + + +     +  IK+   ++  + ++++   +   I  +L
Sbjct: 883  MVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAEL 942

Query: 90   FEKTRKVSAHIKDVKARVEKQQIHVKKVEVKQEEIMKKNKFRVVIFQEKFRCPTSLSVVK 149
              K RK+     ++K  ++  ++ + KVE  +E+   +NK + +  +      T   + K
Sbjct: 943  TAKKRKLEDECSELKKDIDDLELTLAKVE--KEKHATENKVKNLTEEMAGLDETIAKLTK 1000

Query: 150  DRN-LTENQEEDDDDIFDPPVDLSSDEEYYVEESRSARLRKSGKEHIDNIKKAFSKENMQ 208
            ++  L E  ++  DD+          EE  V     A+++   ++ +D+++ +  +E  +
Sbjct: 1001 EKKALQEAHQQTLDDL--------QAEEDKVNTLTKAKIKL--EQQVDDLEGSLEQE--K 1048

Query: 209  KTRQNLDKKVNRIRTRIVTPERRERLRQSGERLRQSGERLRQSGERFKKSISNAAPSKEA 268
            K R +L++   ++   +   +  E +       +Q  E+L++  E    ++ +    ++A
Sbjct: 1049 KLRMDLERAKRKLEGDLKLAQ--ESIMDIENEKQQLDEKLKKK-EFEISNLQSKIEDEQA 1105

Query: 269  FKMRSLRKGKDRTVAEGEECAREMGVDIIARSESLGPISELYS--DELSEPEHEA 321
              ++  +K K+   A  EE   E+  +  +R+++    S+L    +E+SE   EA
Sbjct: 1106 LGIQLQKKIKE-LQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEA 1159



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 22/101 (21%), Positives = 46/101 (45%), Gaps = 2/101 (1%)

Query: 2    EHNGSASNADKIHQNRLSSVT--EDEDQDAALTIVTVLDKVASIVDSVQASQKRIEERHR 59
            + N  A    + H+ R+  +T   +ED+   L +  ++DK+ + V S +   +  EE+  
Sbjct: 1837 KRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSN 1896

Query: 60   EMENAIKSVQIDLLKLSQSHSNTGHIINKLFEKTRKVSAHI 100
                  + +Q +L +  +        +NKL  K+R+V   +
Sbjct: 1897 TNLAKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKV 1937


>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
            sapiens]
          Length = 1941

 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 68/335 (20%), Positives = 137/335 (40%), Gaps = 58/335 (17%)

Query: 14   HQNRLSSVTEDEDQDAALTIVTVLDKVASIVDSVQASQKRIEERHREMENAIKSVQIDLL 73
            HQ  L  +  +ED+   LT   +  K+   VD ++ S ++ ++   ++E A + ++ DL 
Sbjct: 1009 HQQTLDDLQAEEDKVNTLTKAKI--KLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLK 1066

Query: 74   KLSQSHSNTGHIINKLFEKTRKVSAHIKDVKARVEKQQI-------HVKKVEVK----QE 122
               +S  +  +   +L EK +K    I ++++++E +Q         +K+++ +    +E
Sbjct: 1067 LAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEE 1126

Query: 123  EIMKKNKFRVVIFQEKFRCPTSLSVVKDR---------NLTENQEEDDDDIFDPPVDLSS 173
            EI  +   R    +++      L  + +R            E  ++ + +      DL  
Sbjct: 1127 EIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDL-- 1184

Query: 174  DEEYYVEESRSARLRKSGK-------EHIDNIKKAFSK-------------------ENM 207
            +E     E+ +A LRK          E IDN+++   K                   E +
Sbjct: 1185 EEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETV 1244

Query: 208  QKTRQNLDKKVNRIRTRI--VTPERRERLRQSGERLRQSGERLRQSGERFKKSISNAAPS 265
             K + NL+K    +  ++  +  +  E+ R   +   Q G    +SGE      S     
Sbjct: 1245 SKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGE-----FSRQLDE 1299

Query: 266  KEAFKMRSLRKGKDRTVAEGEECAREMGVDIIARS 300
            KEA  +  L +GK     + EE  R++  +I A++
Sbjct: 1300 KEAL-VSQLSRGKQAFTQQIEELKRQLEEEIKAKN 1333



 Score = 32.7 bits (73), Expect = 0.52
 Identities = 55/295 (18%), Positives = 135/295 (45%), Gaps = 24/295 (8%)

Query: 33   IVTVLDKVASIVDSVQASQKRIEERHREMENAIKS---VQIDLLKLSQSHSNTGHIINKL 89
            +VT+L +   +   VQA  + + +     +  IK+   ++  + ++++   +   I  +L
Sbjct: 883  MVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAEL 942

Query: 90   FEKTRKVSAHIKDVKARVEKQQIHVKKVEVKQEEIMKKNKFRVVIFQEKFRCPTSLSVVK 149
              K RK+     ++K  ++  ++ + KVE  +E+   +NK + +  +      T   + K
Sbjct: 943  TAKKRKLEDECSELKKDIDDLELTLAKVE--KEKHATENKVKNLTEEMAGLDETIAKLTK 1000

Query: 150  DRN-LTENQEEDDDDIFDPPVDLSSDEEYYVEESRSARLRKSGKEHIDNIKKAFSKENMQ 208
            ++  L E  ++  DD+          EE  V     A+++   ++ +D+++ +  +E  +
Sbjct: 1001 EKKALQEAHQQTLDDL--------QAEEDKVNTLTKAKIKL--EQQVDDLEGSLEQE--K 1048

Query: 209  KTRQNLDKKVNRIRTRIVTPERRERLRQSGERLRQSGERLRQSGERFKKSISNAAPSKEA 268
            K R +L++   ++   +   +  E +       +Q  E+L++  E    ++ +    ++A
Sbjct: 1049 KLRMDLERAKRKLEGDLKLAQ--ESIMDIENEKQQLDEKLKKK-EFEISNLQSKIEDEQA 1105

Query: 269  FKMRSLRKGKDRTVAEGEECAREMGVDIIARSESLGPISELYS--DELSEPEHEA 321
              ++  +K K+   A  EE   E+  +  +R+++    S+L    +E+SE   EA
Sbjct: 1106 LGIQLQKKIKE-LQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEA 1159



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 22/101 (21%), Positives = 46/101 (45%), Gaps = 2/101 (1%)

Query: 2    EHNGSASNADKIHQNRLSSVT--EDEDQDAALTIVTVLDKVASIVDSVQASQKRIEERHR 59
            + N  A    + H+ R+  +T   +ED+   L +  ++DK+ + V S +   +  EE+  
Sbjct: 1837 KRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSN 1896

Query: 60   EMENAIKSVQIDLLKLSQSHSNTGHIINKLFEKTRKVSAHI 100
                  + +Q +L +  +        +NKL  K+R+V   +
Sbjct: 1897 TNLAKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKV 1937


>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 668

 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 45/250 (18%), Positives = 110/250 (44%), Gaps = 4/250 (1%)

Query: 55  EERHREMENAIKSVQIDLLKLSQSHSNTGHIINKLFEKTRKVSAHIKDVKARVEKQQIHV 114
           EE+ R  E  +   +  + +L +        I +L EK  +     +  + R E+++I  
Sbjct: 348 EEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIRE 407

Query: 115 KKVEVKQEEIMKKNKFRVVIFQEKFRCPTSLSVVKDRNLTENQEEDDDDIFDPPVDLSSD 174
           ++   +QE  M + + ++   +EK R        ++  + E ++  +++      ++   
Sbjct: 408 QEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQ 467

Query: 175 EEYYVEESRSARLRKSGKEHIDNIKKAFSKENMQKTRQNLDKKVNRIRTRIVTPERR-ER 233
           EE   E+    R ++   E  + I+K   +E + +  + +  +  +IR +     R+ E+
Sbjct: 468 EEKIREQEEIWRQKEKMHEQ-EKIRK--QEEKVWRQEEKMHDQEEKIREQEEKMWRQEEK 524

Query: 234 LRQSGERLRQSGERLRQSGERFKKSISNAAPSKEAFKMRSLRKGKDRTVAEGEECAREMG 293
           +R+  E++R+  E++R+  E  ++        +E  + +   + ++  + E EE  RE  
Sbjct: 525 IREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQK 584

Query: 294 VDIIARSESL 303
             I  + E +
Sbjct: 585 EKIREQEEKI 594



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 35/250 (14%), Positives = 111/250 (44%), Gaps = 3/250 (1%)

Query: 45  DSVQASQKRIEERHREMENAIKSVQIDLLKLSQSHSNTGHIINKLFEKTRKVSAHIKDVK 104
           + ++  ++++ E+ +  E   K  + + ++  +        + +  EK R+    I++ +
Sbjct: 377 EKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQE 436

Query: 105 ARVEKQQIHVKKVEVKQEEIMKKNKFRVVIFQEKFRCPTSLSVVKDRNLTENQEEDDDDI 164
            ++ +Q+  + + E  +EE  ++ +  +   +EK R    +   K++   + +    ++ 
Sbjct: 437 KKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEK 496

Query: 165 FDPPVDLSSDEEYYVEESRSARLRKSGKEHIDNIKKAFSKENMQKTRQNLDKKVNRIRTR 224
                +   D+E  + E      R+  K      K    +E +++  + + ++  ++  +
Sbjct: 497 VWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQ 556

Query: 225 IVTPERRERLRQSGERLRQSGERLRQSGERFKKSISNAAPSKEAFK-MRSLRKGKDRTVA 283
               + +E++R+  E++R+  E++R+  E+ ++        +E  +    + + ++  + 
Sbjct: 557 EEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMW 616

Query: 284 EGEE--CARE 291
           E EE  C +E
Sbjct: 617 EQEEKMCEQE 626



 Score = 36.2 bits (82), Expect = 0.047
 Identities = 39/246 (15%), Positives = 108/246 (43%), Gaps = 11/246 (4%)

Query: 51  QKRIEERHREMENAIKSVQIDLLKLSQSHSNTGHIINKLFEKTRKVSAHIKDVKARVEKQ 110
           Q++++     +   ++SV   L    + +     +  +  EK  +    I++ + ++++Q
Sbjct: 260 QQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQ 319

Query: 111 QIHVKKVEVK---QEEIMKKNKFRVVIFQEKFRCPTSLSVVKD---RNLTENQEEDDDDI 164
           +  +++ E K   QEE M++ +  +   +EK R    +   K+   R L E   E ++ I
Sbjct: 320 EEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKI 379

Query: 165 FDPPVDLSSDEEYYVEESR---SARLRKSGKEHIDNIKKAFSKENMQKTRQNLDKKVNRI 221
            +    +   E+   +E +     ++R+  K      K    +E +++  + + ++  ++
Sbjct: 380 RELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKM 439

Query: 222 RTRIVTPERRERLRQSGERLRQSGERLRQSGERFKKSISNAAPSKEAFKMRSLRKGKDRT 281
             +      +E++R+  E  RQ  E + +  E+ ++        ++  +   +RK +++ 
Sbjct: 440 WRQEEKIHEQEKIRE--EEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKV 497

Query: 282 VAEGEE 287
             + E+
Sbjct: 498 WRQEEK 503


>gi|71061468 centromere protein E [Homo sapiens]
          Length = 2701

 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 59/293 (20%), Positives = 140/293 (47%), Gaps = 40/293 (13%)

Query: 1    MEHNGSASNADKI---HQNRLSSVTEDEDQDAALTIVTVLDKVASIV----DSVQASQKR 53
            +EH+  A  A  +    + R++ +   E Q+        +DK+  IV    D +   QK 
Sbjct: 1758 LEHSNDALKAQDLKIQEELRIAHMHLKEQQET-------IDKLRGIVSEKTDKLSNMQKD 1810

Query: 54   IEERHREMENAIKSVQIDLLKLSQSHSNTGHIINKLFEKTRKVSAHIKDVKARVEKQQIH 113
            +E  + +++  I+      LK ++    T   + K   +T+K  + ++ +K +++ Q + 
Sbjct: 1811 LENSNAKLQEKIQE-----LKANEHQLIT---LKKDVNETQKKVSEMEQLKKQIKDQSLT 1862

Query: 114  VKKVEVKQEEIMKKNKFRVVIFQEKFRCPTSLSVVKDRNLTENQEE----DDDDIFDPPV 169
            + K+E++   + +K    +    E+ +     SV+K+R+     EE    + D + +   
Sbjct: 1863 LSKLEIENLNLAQKLHENL----EEMK-----SVMKERDNLRRVEETLKLERDQLKESLQ 1913

Query: 170  DLSSDEEYYVEESRSAR-LRKSGKEHIDNIKKAFSKENMQ--KTRQNLDKKVNRIRTRIV 226
            +  + +    +E ++AR L K  KE +D +++  S++ +Q    +++LDK  + ++ +I 
Sbjct: 1914 ETKARDLEIQQELKTARMLSKEHKETVDKLREKISEKTIQISDIQKDLDKSKDELQKKIQ 1973

Query: 227  TPERRE-RLRQSGERLRQSGERLRQSGERFKKSISNAAPSKEAFKMRSLRKGK 278
              +++E +L +  E +  S +++ +  E+ KK       S ++ +M + +  K
Sbjct: 1974 ELQKKELQLLRVKEDVNMSHKKINEM-EQLKKQFEAQNLSMQSVRMDNFQLTK 2025



 Score = 28.9 bits (63), Expect = 7.6
 Identities = 55/322 (17%), Positives = 132/322 (40%), Gaps = 46/322 (14%)

Query: 36   VLDKVASIVDSVQASQKRIEERHREMENAIKSVQIDL-----LKLSQSHSNTGHIINKLF 90
            +L+++    D +  +Q   +   +E +N  K++ +D      + L ++      I+N   
Sbjct: 794  LLEEIGKTKDDLATTQSNYKSTDQEFQN-FKTLHMDFEQKYKMVLEENERMNQEIVNLSK 852

Query: 91   EKTR----------KVSAHIKDVKARVEKQQIHVKKVEVKQEEIMKKNKFRVVIFQEKFR 140
            E  +          ++S   ++++ +  + Q  + ++E  +E++  ++     + +EK  
Sbjct: 853  EAQKFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTL 912

Query: 141  CPTSLSVVKDRNLTENQEEDD----------------DDIFDPPVDLSSDEEYYVEESRS 184
                L    +   T  QE+DD                 DI D  V+++ D +   E+ R+
Sbjct: 913  ITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQLKSDIHD-TVNMNIDTQ---EQLRN 968

Query: 185  A-RLRKSGKEHIDNIKKAFSKENMQK--TRQNLDKKVNRIRTRIVTPERRERLRQSGERL 241
            A    K  +E I+ +K   S+E  +     +N  +  +  + ++V  ++++ L     + 
Sbjct: 969  ALESLKQHQETINTLKSKISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKNTQT 1028

Query: 242  RQSGERLRQSGERFKKSISNAAPSKEAFKMRSLRKGKDRTVAEGEECAREMGVDIIARSE 301
              +  +  +  E+ +K  S      E      L++  +  +AE E+   ++  +I    E
Sbjct: 1029 LTADVKDNEIIEQQRKIFSLIQEKNE------LQQMLESVIAEKEQLKTDLKENIEMTIE 1082

Query: 302  SLGPISELYSDELSEPEHEAAR 323
            +   +  L  DEL + +   A+
Sbjct: 1083 NQEEL-RLLGDELKKQQEIVAQ 1103


>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
          Length = 780

 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 57/248 (22%), Positives = 103/248 (41%), Gaps = 23/248 (9%)

Query: 89  LFEKTRKVSAHIKDVKARVEKQQIHVKKVEVKQEEIMKKNKFRVVIFQEKFRCPTSLSVV 148
           L EK R+     K    R++       K +  +E  ++ +   + I    +R        
Sbjct: 17  LQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYR-------- 68

Query: 149 KDRNLTENQEEDDDDIFDPPVDLSSDEEYY--VEESRSARLRKSGKEHIDNIKKAFSKEN 206
           ++ ++ +  EEDD     PP  +S  E+ +   +E R  + R       +  K A  KE 
Sbjct: 69  REDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKCRHH-SHSAEGGKHARVKER 127

Query: 207 MQKTRQNLDKKVNRIRTRIVTPERRERLRQSGERLRQSGERLRQSGERFKKSISNAAPSK 266
             + R+   ++ ++ R      +RRE  R+   R R   E+L +  ER +K        +
Sbjct: 128 EHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERK-------MR 180

Query: 267 EAFKMRSLRKGKDRTVAEGEECAREMGVDIIARSESLGPISELYSDELSEPEHEAARPVY 326
           E  K +  +K ++R  AE     RE   ++ A   ++    E YSD++ +  H +  P  
Sbjct: 181 EQQKEQREQKERERR-AEERRKEREARREVSAHHRTM---REDYSDKV-KASHWSRSPPR 235

Query: 327 PPHEGREI 334
           PP E  E+
Sbjct: 236 PPRERFEL 243


>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
          Length = 1411

 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 39/219 (17%), Positives = 98/219 (44%), Gaps = 20/219 (9%)

Query: 57   RHREMENAIKSVQIDLLKLSQSHSNTGHIINKLFEKTRKVSAHIKDVKARVEKQQIHVKK 116
            +H E+ N I++   +L K+          ++ + +K  KVS  +K+ K+  EK+    K 
Sbjct: 826  QHEELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKA 885

Query: 117  VEVKQEEIMKKNKFRVVIFQEKFRCPTSLSVVKDRNLTENQEEDDDDIFDPPVDLSSDEE 176
              +  E+  K+ K ++ +  E        ++ + + L ++ E++ +      ++L+S +E
Sbjct: 886  AILDLEKTCKELKHQLQVQMEN-------TLKEQKELKKSLEKEKEASHQLKLELNSMQE 938

Query: 177  YYVEESRSARLRKSGKEHIDNIKKAFSKENMQKTRQNLDKKVNRIRT-----RIVTPERR 231
              ++   + +  +  ++ +          N+ + +Q+ ++K  +I       +I   ++ 
Sbjct: 939  QLIQAQNTLKQNEKEEQQLQG--------NINELKQSSEQKKKQIEALQGELKIAVLQKT 990

Query: 232  ERLRQSGERLRQSGERLRQSGERFKKSISNAAPSKEAFK 270
            E   +  ++L Q+ + L    E+     +N   S+E FK
Sbjct: 991  ELENKLQQQLTQAAQELAAEKEKISVLQNNYEKSQETFK 1029



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 55/299 (18%), Positives = 125/299 (41%), Gaps = 31/299 (10%)

Query: 24  DEDQDAALTIVTVLDKVASIVDSVQASQKRI---EERHREMENAIKS-----VQIDLLKL 75
           D+ Q+    +    D+V S+  SV     ++   +E+  +++  IK+     +  +  K 
Sbjct: 600 DQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKEKVSQLDIQIKAKTELLLSAEAAKT 659

Query: 76  SQSHSNTGHI-------------INKLFEKTRKVSAHIKDVKARVEKQQIHVKKVEVKQE 122
           +Q      H+             +NK+  +  +V+A ++D +    + + H+K+ + K  
Sbjct: 660 AQRADLQNHLDTAQNALQDKQQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYL 719

Query: 123 EIMKKNKFRVVIFQEKFRCPTSLSVVKDRNLTENQEED--DDDIFDPPVDLSSDEEYYVE 180
            + +K +      ++       +   K++ L + Q++   + D+     +LS   E   E
Sbjct: 720 SLEQKTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKE 779

Query: 181 ESRSARLRKSGK-EHIDNIKKAFSKENMQKTRQNLDKKVNRIRTRIVTPERRERLRQSG- 238
              S RL    K E +++IK+  +K+  +K     D +     T+I   E   R++ +  
Sbjct: 780 IVSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVT 839

Query: 239 --ERLRQSGERLRQSGERFKKSISNAAPSKEAFKM---RSLRKGKDRTVAEGEECAREM 292
             ++++   E L       K  +S  + S +  K    +  +KGK   + + E+  +E+
Sbjct: 840 ELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGK-AAILDLEKTCKEL 897



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 26/104 (25%), Positives = 53/104 (50%), Gaps = 11/104 (10%)

Query: 26  DQDAALT-IVTVLDKVASIVDSVQASQKRIEERHREMENAIKSVQIDLLKLSQSHSNTGH 84
           +++A +T + TV DK++ + DS++ S+   E+ +++ + AI       L L ++     H
Sbjct: 847 EKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAI-------LDLEKTCKELKH 899

Query: 85  IINKLFEKTRKVSAHIKDVKARVEKQQIHVKKVEVK--QEEIMK 126
            +    E T K    +K      EK+  H  K+E+   QE++++
Sbjct: 900 QLQVQMENTLKEQKELKK-SLEKEKEASHQLKLELNSMQEQLIQ 942



 Score = 30.4 bits (67), Expect = 2.6
 Identities = 45/238 (18%), Positives = 102/238 (42%), Gaps = 33/238 (13%)

Query: 53  RIEERHREMENAIKSVQIDL-----------LKLSQSHSNTGHIINKLFEK---TRKVSA 98
           ++EE+H E   + K++Q  L            +LS S ++   I  +L EK   T+K+  
Sbjct: 320 KLEEKHNEESVSKKNIQATLHQKDLDCQQLQSRLSASETSLHRIHVELSEKGEATQKLKE 379

Query: 99  HIKDVKARVEKQQIHVKKVEVKQEEIMKKNKFRVVIFQEKFRCPTSLSVVKDR------N 152
            + +V+ + +  +   K+++ ++EE   K +  + +  E  +  + L   + +       
Sbjct: 380 ELSEVETKYQHLKAEFKQLQQQREE---KEQHGLQLQSEINQLHSKLLETERQLGEAHGR 436

Query: 153 LTENQEEDDDDIFDPPVDLSSDEEYYVEESRSARLRKSGKEHIDN---IKKAFSKENMQK 209
           L E ++   + + D       +++    + + +RL +  KE + N   ++    K   Q 
Sbjct: 437 LKEQRQLSSEKLMD------KEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQH 490

Query: 210 TRQNLDKKVNRIRTRIVTPERRERLRQSGERLRQSGERLRQSGERFKKSISNAAPSKE 267
             Q   ++    + R    +  + LRQ G++  Q  + L    ++ K++IS     +E
Sbjct: 491 QEQQALQQSTTAKLREAQNDLEQVLRQIGDK-DQKIQNLEALLQKSKENISLLEKERE 547


>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
            sapiens]
          Length = 1938

 Score = 45.8 bits (107), Expect = 6e-05
 Identities = 43/232 (18%), Positives = 104/232 (44%), Gaps = 26/232 (11%)

Query: 14   HQNRLSSVTEDEDQDAALTIVTVLDKVASIVDSVQASQKRIEERHREMENAIKSVQIDLL 73
            HQ  L  +  +ED+   L  + +  K+    D ++ S ++ ++   ++E A + ++ DL 
Sbjct: 1007 HQQTLDDLQVEEDKVNGL--IKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLK 1064

Query: 74   KLSQSHSNTGHIINKLFEKTRKVSAHIKDVKARVEKQQIHV-----------KKVEVKQE 122
               +S  +  +   ++ EK +K    +  ++A+++ +Q+H             ++E  +E
Sbjct: 1065 MSQESIMDLENDKQQIEEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEE 1124

Query: 123  EIMKKNKFRVVIFQEKFRCPTSLSVVKDR---------NLTENQEEDDDDIFDPPVDLSS 173
            EI  ++  R  I +++      L  + +R            E  ++ + +      DL  
Sbjct: 1125 EIEAEHTLRAKIEKQRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDL-- 1182

Query: 174  DEEYYVEESRSARLRKSGKEHIDNIKKAFSKENMQKTRQNLDKKVNRIRTRI 225
            +E     E+ +A LRK   + +  + +    +N+Q+ +Q L+K+ + ++  I
Sbjct: 1183 EEATLQHEATAATLRKKQADSVAELGEQI--DNLQRVKQKLEKEKSELKMEI 1232



 Score = 28.5 bits (62), Expect = 9.9
 Identities = 45/184 (24%), Positives = 69/184 (37%), Gaps = 37/184 (20%)

Query: 4    NGSASNADKIHQNRLSSVTED--EDQDAALTIVTVLDKVASIVDSVQA--------SQKR 53
            N   ++ +K  Q RL    ED   D + + T    LDK     D V A        SQ  
Sbjct: 1412 NSKCASLEKTKQ-RLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAE 1470

Query: 54   IEERHRE----------MENAIKSVQIDLLKLSQSHSNTGHIINKLFEKTRKVSAHIKDV 103
            +E   +E          M NA + V   L  L + + N    I+ L E+  +   ++++ 
Sbjct: 1471 LEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEA 1530

Query: 104  K-----ARVEKQQIHVKKVEVKQEEIMKKNKFRVVIFQEKFRCPTSLSVVK---DRNLTE 155
            +        EK  + V   EV+     +++K          R    LS VK   DR + E
Sbjct: 1531 EKTKKLVEQEKSDLQVALEEVEGSLEHEESKI--------LRVQLELSQVKSELDRKVIE 1582

Query: 156  NQEE 159
              EE
Sbjct: 1583 KDEE 1586


>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 523

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 64/328 (19%), Positives = 135/328 (41%), Gaps = 42/328 (12%)

Query: 15  QNRLSSVTEDEDQDAALTIVTVLDKVASIV----DSVQASQKRIEERHREMENAIKSVQI 70
           + R SS T ++ +     +   LD  ++I+    +++ +  +  +E  +   + ++ +  
Sbjct: 76  EGRASSTTLEDLESQYQELAVALDSSSAIISQLTENINSLVRTSKEEKKHEIHLVQKLGR 135

Query: 71  DLLKLSQSHSNT--------GHIINKLFEKTRKVSAHIKDV----KARVEKQQIHVKKVE 118
            L KL    +             + +L ++T  +   ++ V    +A VE  Q+ +  + 
Sbjct: 136 SLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQLQAEVENNQM-LSLLN 194

Query: 119 VKQEEIMKKNKFRVVIFQEKFRCPTSLSVVKDRNLTENQEEDDDDIFDPPVDLSSDEEYY 178
            +QEE +++ + R+   +E+ R        ++  L E +E            L   EE  
Sbjct: 195 RRQEERLREQEERLREQEERLREQEERLCEQEERLREQEER-----------LREQEERL 243

Query: 179 VEESRSARLRKSGKEHIDNIKKAFSKEN-MQKTRQNLDKKVNRIRTRIVTPERRERLRQS 237
            E+    RLR+  +   +  ++   +E  +++  + L ++  R+       E+ ERLR+ 
Sbjct: 244 CEQEE--RLREHEERLCEQEERLCEQEERLREQEERLHEQEERLC------EQEERLREQ 295

Query: 238 GERLRQSGERLRQSGERFKKSISNAAPSKEAFKMRSLRKGKDRTVAEGE-----ECAREM 292
            ERL +  ERLR+  ER  +        +E    +    G++R + E E     E  +E 
Sbjct: 296 EERLCEQEERLREQEERLCEQEERLREQEERLCEQEKLPGQERLLEEVEKLLEQERRQEE 355

Query: 293 GVDIIARSESLGPISELYSDELSEPEHE 320
              ++ R   L  + EL   E    + E
Sbjct: 356 QERLLERERLLEEVEELLEQERLRQQDE 383


>gi|55770895 ERBB2 interacting protein isoform 7 [Homo sapiens]
          Length = 1302

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 42/154 (27%), Positives = 75/154 (48%), Gaps = 12/154 (7%)

Query: 60  EMENAIKSVQ--IDLLKLSQSHSNTGHIINKLFEKTRKVSAHIKDVKARVEKQQIHVKKV 117
           E++N +K+VQ  +  LK  +++ ++G  + K  E  + ++   KDV  +  +    VK  
Sbjct: 490 ELKNMVKTVQTIVHRLKDEETNEDSGRDL-KPHEDQQDIN---KDVGVKTSESTTTVKSK 545

Query: 118 EVKQEEIMKKNKFRVVIFQEKFRCPTSLSVVKDRNLTENQEE--DDDDIFDPPVDLSSDE 175
             ++E+ M  N  + +   E    P SL V  +   +EN +   + DD+F+   +LSSDE
Sbjct: 546 VDEREKYMIGNSVQKISEPEAEISPGSLPVTANMKASENLKHIVNHDDVFEESEELSSDE 605

Query: 176 EYYVEESRSARLRKSGKE----HIDNIKKAFSKE 205
           E  + E R   +  S  +     + N KK  +KE
Sbjct: 606 EMKMAEMRPPLIETSINQPKVVALSNNKKDDTKE 639


>gi|8923909 ERBB2 interacting protein isoform 2 [Homo sapiens]
          Length = 1371

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 42/154 (27%), Positives = 75/154 (48%), Gaps = 12/154 (7%)

Query: 60  EMENAIKSVQ--IDLLKLSQSHSNTGHIINKLFEKTRKVSAHIKDVKARVEKQQIHVKKV 117
           E++N +K+VQ  +  LK  +++ ++G  + K  E  + ++   KDV  +  +    VK  
Sbjct: 490 ELKNMVKTVQTIVHRLKDEETNEDSGRDL-KPHEDQQDIN---KDVGVKTSESTTTVKSK 545

Query: 118 EVKQEEIMKKNKFRVVIFQEKFRCPTSLSVVKDRNLTENQEE--DDDDIFDPPVDLSSDE 175
             ++E+ M  N  + +   E    P SL V  +   +EN +   + DD+F+   +LSSDE
Sbjct: 546 VDEREKYMIGNSVQKISEPEAEISPGSLPVTANMKASENLKHIVNHDDVFEESEELSSDE 605

Query: 176 EYYVEESRSARLRKSGKE----HIDNIKKAFSKE 205
           E  + E R   +  S  +     + N KK  +KE
Sbjct: 606 EMKMAEMRPPLIETSINQPKVVALSNNKKDDTKE 639


>gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]
          Length = 330

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 33/138 (23%), Positives = 66/138 (47%), Gaps = 5/138 (3%)

Query: 153 LTENQEEDDDDIFDPPVDLSSDEEYYVEESRSARLRKSGKEHIDNIKKAFSKENMQKTRQ 212
           L E+++EDD D+    +D S +E+   ++S      KS   H  +  ++ S  + +   +
Sbjct: 169 LDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSR 228

Query: 213 NLDKKVNRIRTRIVTPERRERLRQSGERLRQSGERLRQSGERFKKSISNAAPSKEAFKMR 272
           +  +  +  ++R  +  R ER R  G + R S    R S    K+S S+++ S E    R
Sbjct: 229 SRSRSSSSSQSRSRSSSR-ERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPE----R 283

Query: 273 SLRKGKDRTVAEGEECAR 290
           + ++ + R+ + G+   R
Sbjct: 284 NRKRSRSRSSSSGDRKKR 301


>gi|239745083 PREDICTED: similar to Golgin subfamily A member 8-like
           protein 1 isoform 4 [Homo sapiens]
          Length = 590

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 70/328 (21%), Positives = 132/328 (40%), Gaps = 55/328 (16%)

Query: 9   NADKIHQNRLSSVTEDEDQDAALTIVTVLDKVASI---VDSVQASQKRIEERHREMENAI 65
           N D  H  R     E+E +D A+ +   L +   +   + +V A+QK+  ER      A 
Sbjct: 138 NTDLYHTKRSLRYFEEESKDLAVRLQHSLQRKGELERALSAVTATQKKKAERFSSRSKAR 197

Query: 66  KSVQIDLLKLSQSHSNTGHIINKLFEKTRKVSAHIKDVKARVEKQQIHVKKVEVKQEEIM 125
                   KL QS      +  +L +    +   +K+V+   ++   H+K    + ++ M
Sbjct: 198 TE-----WKLEQSMREQALLKAQLTQ----LKESLKEVQLERDEYAEHLKGERARWQQRM 248

Query: 126 KKNKFRVVIFQEKFRCPTSLSVVKDRNLTENQEEDDDDIFDPPVDLSSDEEYYVEESRSA 185
           +K    V   +++ +         +R+L++ + +  + +   P  + S+ E         
Sbjct: 249 RKMSQEVCSLKKEKKHDKYRVETLERSLSKLKNQMAEPLPPEPPAVPSEAELQ------- 301

Query: 186 RLRKSGKEHIDNIKKAFSKENMQKTRQNLDKKVNRIRTRIVTPERRERLRQSGERLRQSG 245
            LRK   E +    +A  + N               R  ++   ++ERLR+  ERL +  
Sbjct: 302 HLRKE-LERVAGALQAQVEYNQ--------------RISLLNEGQKERLREQQERLPEQE 346

Query: 246 ERLRQSGERFKKSISNAAPSKEAFKMRSLRKGKDRTVAEGEECAREMGVDIIARSESLGP 305
           ERL+Q  E            + +FK  +    ++++V + E+  +E+        E LG 
Sbjct: 347 ERLQQLAE-----------PQNSFKELN---NENKSVLQLEQQVKEL-------QEKLGK 385

Query: 306 ISELYSDELSEPEHEAARPVYPPHEGRE 333
           + E  +   S+ E EAAR    P  G E
Sbjct: 386 VKETVTSTPSKKEPEAARGPGAPGPGGE 413


>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
          Length = 770

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 54/246 (21%), Positives = 101/246 (41%), Gaps = 29/246 (11%)

Query: 89  LFEKTRKVSAHIKDVKARVEKQQIHVKKVEVKQEEIMKKNKFRVVIFQEKFRCPTSLSVV 148
           L EK R+     K    R++       K +  +E  ++ +   + I    +R        
Sbjct: 17  LQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYR-------- 68

Query: 149 KDRNLTENQEEDDDDIFDPPVDLSSDEEYYVEESRSARLRKSGKEHIDNIKKAFSKENMQ 208
           ++ ++ +  EEDD     PP  +S  E+ +          +  ++  +  K A  KE   
Sbjct: 69  REDSMEDRGEEDDSLAIKPPQQMSRKEKVH---------HRKDEKRKEKWKHARVKEREH 119

Query: 209 KTRQNLDKKVNRIRTRIVTPERRERLRQSGERLRQSGERLRQSGERFKKSISNAAPSKEA 268
           + R+   ++ ++ R      +RRE  R+   R R   E+L +  ER +K        +E 
Sbjct: 120 ERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERK-------MREQ 172

Query: 269 FKMRSLRKGKDRTVAEGEECAREMGVDIIARSESLGPISELYSDELSEPEHEAARPVYPP 328
            K +  +K ++R  AE     RE   ++ A   ++    E YSD++ +  H +  P  PP
Sbjct: 173 QKEQREQKERERR-AEERRKEREARREVSAHHRTM---REDYSDKV-KASHWSRSPPRPP 227

Query: 329 HEGREI 334
            E  E+
Sbjct: 228 RERFEL 233


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 51/226 (22%), Positives = 99/226 (43%), Gaps = 19/226 (8%)

Query: 94   RKVSAHIKDVKARVEKQQIHVKKVEVK---QEEIMKKNKFRVVIFQE---KFRCPTSLSV 147
            +++S   +D K R+E+Q++  ++ E K    E+ +++ + +  + QE   KFR    L  
Sbjct: 1570 QQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQ 1629

Query: 148  VKDRNLTENQEEDDDDIFDPPVDLSSDEEYYVEESRSARLRKS------GKEHI---DNI 198
             ++      QE D   + + P     + E  +   R  + R+       G+E        
Sbjct: 1630 EREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQER 1689

Query: 199  KKAFSKENMQKTRQNLDKKVNRIRTRIVTPERRERLRQSGERLRQ--SGERLRQSGERFK 256
             + F +E  Q  RQ  ++K  +   ++   E   + R+  E+LRQ    E+LR+  ER++
Sbjct: 1690 DRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREE-EQLRQETEQEQLRRQ-ERYR 1747

Query: 257  KSISNAAPSKEAFKMRSLRKGKDRTVAEGEECAREMGVDIIARSES 302
            K +       E  + +  R+ +DR   E E+  +E     +   ES
Sbjct: 1748 KILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQES 1793



 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 62/323 (19%), Positives = 129/323 (39%), Gaps = 47/323 (14%)

Query: 11   DKIHQNRLSSVTEDEDQDAALTIVTVLDKVASIVDSVQASQKRIEERHREMENAIKSVQI 70
            +++ + +      DEDQ + L      +K  ++ D+    + R  E+ R++E++      
Sbjct: 1203 EELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDS------ 1256

Query: 71   DLLKLSQSHSNTGHIINKLFEKTRKVS------------------------AHIKDVKAR 106
              L+  QS  +  H++ +  E+ R+                          A  +D K++
Sbjct: 1257 -QLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQ 1315

Query: 107  VEKQQIHVKKVEVKQ-EEIMKKNKFRVVIFQEKFRCPTSLSVVKDRNLTENQ---EEDDD 162
             EKQ +  ++ E ++ +E  +K +    + QE+   P      +DR   E +   +E   
Sbjct: 1316 EEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQE-RDRKFREEELRHQEQGR 1374

Query: 163  DIFDPPVDLSSDEEY--YVEESRSARLRKSGKEHIDNIKKAFSKENMQKTRQNLDKKVNR 220
               +    L   E    +++E +  R ++  ++   +  + F +E  Q +RQ  D+K   
Sbjct: 1375 KFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFRE 1434

Query: 221  IRTRIVTPERRERLRQSGERLRQSGERLRQSGERFKKSISNAAPSKEAFKMRSLRKGKDR 280
               ++   ER  +  +  ++LRQ         ER +K        +E  + +  R+ +DR
Sbjct: 1435 EEQQVRRQERERKFLEEEQQLRQ---------ERHRKFREEEQLLQEREEQQLHRQERDR 1485

Query: 281  TVAEGEECAREMGVDIIARSESL 303
               E E+  R    D   R + L
Sbjct: 1486 KFLEEEQQLRRQERDRKFREQEL 1508



 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 46/232 (19%), Positives = 96/232 (41%), Gaps = 24/232 (10%)

Query: 88   KLFEKTRKVSAHIKDVKARVEKQQIHVKKVEVK---QEEIMKKNKFRVVIFQEKFRCPTS 144
            K  E+ +++S   +D K R E+QQ+  ++ E K   +E+ +++ + R      KFR    
Sbjct: 1415 KFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHR------KFREEEQ 1468

Query: 145  LSVVKDRNLTENQEED---------------DDDIFDPPVDLSSDEEYYVEESRSARLRK 189
            L   ++      QE D               D    +  +     E  ++EE +    ++
Sbjct: 1469 LLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQ 1528

Query: 190  SGKEHIDNIKKAFSKENMQKTRQNLDKKVNRIRTRIVTPERRERLRQSGERLRQSGERLR 249
              ++ +   ++   +E  Q+ RQ+ D+K           E ++  RQ  +R  +  E+  
Sbjct: 1529 RQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKV 1588

Query: 250  QSGERFKKSISNAAPSKEAFKMRSLRKGKDRTVAEGEECAREMGVDIIARSE 301
            +  E+ +K + +    +     + LR+ +DR   E E+  +E     + R E
Sbjct: 1589 RRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQE 1640



 Score = 34.7 bits (78), Expect = 0.14
 Identities = 36/203 (17%), Positives = 89/203 (43%), Gaps = 24/203 (11%)

Query: 88   KLFEKTRKVSAHIKDVKARVEKQQIHVKKVEVKQEEIMKKNKFRVVIFQEKFRCPTSLSV 147
            K  ++ +++     + K R E+Q     + E +QE++ ++ ++R ++ +E+ R       
Sbjct: 1708 KFLQEEQQLRRQELERKFREEEQL----RQETEQEQLRRQERYRKILEEEQLR------- 1756

Query: 148  VKDRNLTENQEEDDDDIFDPPVDLSSDEEYYVEESRSARLRKSGKEHIDNIKKAFSKENM 207
              +R   + + ++ D  F        +EE   +E    +LR    +     +K   +E +
Sbjct: 1757 -PEREEQQLRRQERDRKF-------REEEQLRQEREEQQLRSQESD-----RKFREEEQL 1803

Query: 208  QKTRQNLDKKVNRIRTRIVTPERRERLRQSGERLRQSGERLRQSGERFKKSISNAAPSKE 267
            ++ R+    +  +   +    E + +L +  +RLRQ  +R  ++ E+F     +    +E
Sbjct: 1804 RQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQE 1863

Query: 268  AFKMRSLRKGKDRTVAEGEECAR 290
             ++    ++ ++R     EE  R
Sbjct: 1864 LWQEEEQKRRQERERKLREEHIR 1886



 Score = 33.1 bits (74), Expect = 0.40
 Identities = 36/189 (19%), Positives = 80/189 (42%), Gaps = 23/189 (12%)

Query: 108  EKQQIHVKKVEVK--QEEIMKKNKFRVVIFQEKFRCPTSLSVVKDRNLTENQEEDDDDIF 165
            E+QQ+H ++ + K  +EE   + + R      KFR     S   +R   E +++      
Sbjct: 1474 EEQQLHRQERDRKFLEEEQQLRRQER----DRKFREQELRSQEPERKFLEEEQQ------ 1523

Query: 166  DPPVDLSSDEEYYVEESRSARLRKSGKEHIDNIKKAF--------SKENMQKTRQNLDKK 217
               +     +  +++E +  R ++ G++   +  + F         +E  Q +RQ  D+K
Sbjct: 1524 ---LHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRK 1580

Query: 218  VNRIRTRIVTPERRERLRQSGERLRQSGERLRQSGERFKKSISNAAPSKEAFKMRSLRKG 277
                  ++   E+  +  +  ++LR+   + +   ER +K   +    +E  + +  R+ 
Sbjct: 1581 FRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQE 1640

Query: 278  KDRTVAEGE 286
            +DR   E E
Sbjct: 1641 RDRKFLEEE 1649


>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           4 [Homo sapiens]
          Length = 737

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 48/192 (25%), Positives = 84/192 (43%), Gaps = 32/192 (16%)

Query: 149 KDRNLTENQEEDDDDIFDPPVDLSSDEEYY------VEESRSARLRKSGKEHIDNIKKAF 202
           ++ ++ +  EEDD     PP  +S  E+ +       +E + AR+++  +EH        
Sbjct: 35  REDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREH-------- 86

Query: 203 SKENMQKTRQNLDKKVNRIRTRIVTPERRERLRQSGERLRQSGERLRQSGERFKKSISNA 262
             E  ++ R+  DK     R      +RRE  R+   R R   E+L +  ER +K     
Sbjct: 87  --ERRKRHREEQDK----ARREWERQKRREMAREHSRRERDRLEQLERKRERERK----- 135

Query: 263 APSKEAFKMRSLRKGKDRTVAEGEECAREMGVDIIARSESLGPISELYSDELSEPEHEAA 322
              +E  K +  +K ++R  AE     RE   ++ A   ++    E YSD++ +  H + 
Sbjct: 136 --MREQQKEQREQKERERR-AEERRKEREARREVSAHHRTM---REDYSDKV-KASHWSR 188

Query: 323 RPVYPPHEGREI 334
            P  PP E  E+
Sbjct: 189 SPPRPPRERFEL 200


>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
           sapiens]
          Length = 570

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 39/227 (17%), Positives = 105/227 (46%), Gaps = 15/227 (6%)

Query: 38  DKVASIVDSVQASQKRI---EERHREMENAIKSVQIDLLKLSQSHSNTGHIINKLFEKTR 94
           +K+    + +Q  +++I   EE+ R  E  +   +  + +  +        I +L EK  
Sbjct: 295 EKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMH 354

Query: 95  KVSAHIKDVKARVEKQQIHVKKVEVKQEEIMKKNKFRVVIFQEKFRCPTSLSVVKDRNLT 154
           +     +  + R E+++I  ++   +QE  M + + ++   +EK R    +   ++  + 
Sbjct: 355 EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMG 414

Query: 155 ENQE---EDDDDIFDPPVDLSSDEEYYVEESRSARLRKSGKEHIDNIKKAFSKENMQKTR 211
           E +E   E ++++ +    +   EE   E+ +  R      E  + I++   +E MQ+  
Sbjct: 415 EQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIR------EQEEKIRE--QEEMMQEQE 466

Query: 212 QNLDKKVNRI-RTRIVTPERRERLRQSGERLRQSGERLRQSGERFKK 257
           + + ++  ++        E+ E++R+  E++R+  +++R+  E+ ++
Sbjct: 467 EKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIRE 513



 Score = 30.4 bits (67), Expect = 2.6
 Identities = 67/380 (17%), Positives = 154/380 (40%), Gaps = 50/380 (13%)

Query: 14  HQNRLSSVTEDEDQDAALTIVTVLDKVASIVDSVQASQKRIEERHREMENAIKSVQIDLL 73
           HQ++ +   E E Q   + I+T   +   +  ++  SQ  +++   E  + I        
Sbjct: 103 HQHQEALRRELEAQVQTIRILTC--QKTELQMALYYSQHAVKQLEGEARDLIS------- 153

Query: 74  KLSQSHSNTGHI---INKLFEKTRKVSAHIKDVKARVEKQQIHVKKVEVKQEEIMKKNKF 130
           +L  S    G +   ++ +  + +K   +I+++    +   + + +  +  EE+ +KN  
Sbjct: 154 RLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKN-- 211

Query: 131 RVVIFQEKFRCPTSLSVVKDRNLTENQEE-DDDDIFDPPVDLSSDEEYYVEE--SRSARL 187
                QEK +   S       N+ E + + +   +  P   L ++ ++  +E  S SA+L
Sbjct: 212 --AKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKL 269

Query: 188 RKSGKEHI--------DNIKKAFSKENMQKTRQNLDKKVNRIRTR--------IVTPERR 231
           +   +E+            K    +E +Q+  + + ++  +IR +         +  E+ 
Sbjct: 270 QAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKE 329

Query: 232 ERLRQSGERLRQSGERLRQSGERF---KKSISNAAPSKEAFKMRSLRKGKDR-------- 280
           E++R+  E + +  E++R+  E+    +K        +E  K+R   K +++        
Sbjct: 330 EKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE 389

Query: 281 -TVAEGEECAREMGVDIIARSESLGPISEL---YSDELSEPEHEAARPVYPPHEGREIPT 336
             + E EE  RE    +  + E +G   E      +E+ E E +  R      E  +   
Sbjct: 390 EKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIR 449

Query: 337 PEPLKVTFKSQVKVEDDESL 356
            +  K+  + ++  E +E +
Sbjct: 450 EQEEKIREQEEMMQEQEEKM 469



 Score = 28.9 bits (63), Expect = 7.6
 Identities = 20/122 (16%), Positives = 56/122 (45%), Gaps = 2/122 (1%)

Query: 38  DKVASIVDSVQASQKRIEERHREMENAIKSVQIDLLKLSQSHSNTGHIINKLFEKTRKVS 97
           +K+    + ++  +K+I E+  ++    + +Q    K+ +          K+ E+  K+ 
Sbjct: 432 EKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMR 491

Query: 98  AHIKDVKARVEKQQIHVKKVEVKQEEIMKKNKFRVVIFQEKFRCPTSLSVVKDRNLTENQ 157
              ++ K R ++++I  ++ +++++E M + +   +  QE+  C     + +       Q
Sbjct: 492 R--QEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQ 549

Query: 158 EE 159
           EE
Sbjct: 550 EE 551


>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           5 [Homo sapiens]
          Length = 748

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 45/189 (23%), Positives = 82/189 (43%), Gaps = 15/189 (7%)

Query: 149 KDRNLTENQEEDDDDIFDPPVDLSSDEEYY---VEESRSARLRKSGKEHIDNIKKAFSKE 205
           ++ ++ +  EEDD     PP  +S  E+ +    E+ +  R  +S         +   KE
Sbjct: 35  REDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKRRHRSHSAEGGKHARVKEKE 94

Query: 206 NMQKTRQNLDKKVNRIRTRIVTPERRERLRQSGERLRQSGERLRQSGERFKKSISNAAPS 265
              + R+   ++ ++ R      +RRE  R+   R R   E+L +  ER +K        
Sbjct: 95  REHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERK-------M 147

Query: 266 KEAFKMRSLRKGKDRTVAEGEECAREMGVDIIARSESLGPISELYSDELSEPEHEAARPV 325
           +E  K +  +K ++R  AE     RE   ++ A   ++    E YSD++ +  H +  P 
Sbjct: 148 REQQKEQREQKERERR-AEERRKEREARREVSAHHRTM---REDYSDKV-KASHWSRSPP 202

Query: 326 YPPHEGREI 334
            PP E  E+
Sbjct: 203 RPPRERFEL 211


>gi|22758136 MAP7 domain containing 2 [Homo sapiens]
          Length = 732

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 34/134 (25%), Positives = 58/134 (43%), Gaps = 12/134 (8%)

Query: 170 DLSSDEEYYVEESRSARLRKSGKEHIDNIKKAFSKENMQKTRQNLDKKVNRIRTRIVTPE 229
           D     +   E+ R ARL+K  +E     ++   +E  +  R+ L +K    R R+    
Sbjct: 396 DAGEAAKILAEKRRQARLQKEQEEQ----ERVEKEEQDRLEREELKRKAEEERLRLEEEA 451

Query: 230 RR---ERLRQSGERLRQSGERLRQSGERFKKSISNAAPSKEAFKMRS-----LRKGKDRT 281
           R+   ER RQ  E+ +Q GE  R++GE  K+        KE  +        + K K+  
Sbjct: 452 RKQEEERKRQEEEKKKQEGEEKRKAGEEAKRKAEEELLLKEKQEQEKQEKAMIEKQKEAA 511

Query: 282 VAEGEECAREMGVD 295
             +  E A +M ++
Sbjct: 512 ETKAREVAEQMRLE 525



 Score = 28.9 bits (63), Expect = 7.6
 Identities = 36/199 (18%), Positives = 82/199 (41%), Gaps = 17/199 (8%)

Query: 52  KRIEERHREMENAIKSVQIDLLKLSQSHSNTGHIINKLFEKTRKVSAHIKDVKARVEKQQ 111
           K   E+H             L K +   ++ G     L EK R+         AR++K+Q
Sbjct: 367 KHASEKHAAAAGGKAENSAALGKPTAGTTDAGEAAKILAEKRRQ---------ARLQKEQ 417

Query: 112 IHVKKVEVKQEEIMKKNKFRVVIFQEKFRCPTSLSVVKDRNLTE-----NQEEDDDDIFD 166
              ++VE ++++ +++ + +    +E+ R        ++    +      QE ++     
Sbjct: 418 EEQERVEKEEQDRLEREELKRKAEEERLRLEEEARKQEEERKRQEEEKKKQEGEEKRKAG 477

Query: 167 PPVDLSSDEEYYVEESRSARLRKSGKEHIDNIKKAFSKENMQKTRQ-NLDKKVNRIRTRI 225
                 ++EE  ++E +     K  K  I+  K+A   +  +   Q  L+++   ++   
Sbjct: 478 EEAKRKAEEELLLKEKQEQ--EKQEKAMIEKQKEAAETKAREVAEQMRLEREQIMLQIEQ 535

Query: 226 VTPERRERLRQSGERLRQS 244
              ER++R+ +  +R R+S
Sbjct: 536 ERLERKKRIDEIMKRTRKS 554


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.127    0.337 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,830,237
Number of Sequences: 37866
Number of extensions: 563489
Number of successful extensions: 3847
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 104
Number of HSP's successfully gapped in prelim test: 410
Number of HSP's that attempted gapping in prelim test: 3068
Number of HSP's gapped (non-prelim): 965
length of query: 364
length of database: 18,247,518
effective HSP length: 104
effective length of query: 260
effective length of database: 14,309,454
effective search space: 3720458040
effective search space used: 3720458040
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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