BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|66348091 vacuolar protein sorting 13C protein isoform 1B [Homo sapiens] (3585 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|66348091 vacuolar protein sorting 13C protein isoform 1B [Hom... 7028 0.0 gi|42544121 vacuolar protein sorting 13C protein isoform 1A [Hom... 7016 0.0 gi|66347845 vacuolar protein sorting 13C protein isoform 2B [Hom... 7007 0.0 gi|66347828 vacuolar protein sorting 13C protein isoform 2A [Hom... 6995 0.0 gi|15619008 vacuolar protein sorting 13A isoform B [Homo sapiens] 1679 0.0 gi|66346676 vacuolar protein sorting 13A isoform D [Homo sapiens] 1679 0.0 gi|66346674 vacuolar protein sorting 13A isoform A [Homo sapiens] 1679 0.0 gi|66346672 vacuolar protein sorting 13A isoform C [Homo sapiens] 1627 0.0 gi|54607141 vacuolar protein sorting 13D isoform 2 [Homo sapiens] 234 2e-60 gi|54607139 vacuolar protein sorting 13D isoform 1 [Homo sapiens] 234 2e-60 gi|35493713 vacuolar protein sorting 13B isoform 5 [Homo sapiens] 107 2e-22 gi|35493701 vacuolar protein sorting 13B isoform 1 [Homo sapiens] 107 2e-22 gi|119874215 vacuolar protein sorting 13B isoform 4 [Homo sapiens] 84 3e-15 gi|35493725 vacuolar protein sorting 13B isoform 3 [Homo sapiens] 84 3e-15 gi|118197272 ATG2 autophagy related 2 homolog B [Homo sapiens] 52 1e-05 gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 41 0.019 gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 41 0.024 gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 38 0.16 gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 38 0.21 gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 38 0.21 gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 38 0.21 gi|55770834 centromere protein F [Homo sapiens] 38 0.21 gi|13699824 kinesin family member 11 [Homo sapiens] 37 0.27 gi|239746976 PREDICTED: similar to paraneoplastic antigen MA1 [H... 37 0.46 gi|169217313 PREDICTED: similar to paraneoplastic antigen MA1 [H... 36 0.60 gi|32880208 diaphanous homolog 3 isoform b [Homo sapiens] 36 0.60 gi|110225351 diaphanous homolog 3 isoform a [Homo sapiens] 36 0.60 gi|51988900 XPG-complementing protein [Homo sapiens] 36 0.78 gi|36031016 CTCL tumor antigen L14-2 [Homo sapiens] 35 1.3 gi|55749659 UHRF1 (ICBP90) binding protein 1-like isoform b [Hom... 35 1.7 >gi|66348091 vacuolar protein sorting 13C protein isoform 1B [Homo sapiens] Length = 3585 Score = 7028 bits (18234), Expect = 0.0 Identities = 3585/3585 (100%), Positives = 3585/3585 (100%) Query: 1 MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAG 60 MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAG Sbjct: 1 MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAG 60 Query: 61 QIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEE 120 QIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEE Sbjct: 61 QIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEE 120 Query: 121 ALQKAAEKDKPKEAKKDTFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLG 180 ALQKAAEKDKPKEAKKDTFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLG Sbjct: 121 ALQKAAEKDKPKEAKKDTFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLG 180 Query: 181 ELSLLTANEHWTPCILNEADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILDQLKNEIL 240 ELSLLTANEHWTPCILNEADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILDQLKNEIL Sbjct: 181 ELSLLTANEHWTPCILNEADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILDQLKNEIL 240 Query: 241 TSGNIPPNYQYIFQPISASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKPQYLSMID 300 TSGNIPPNYQYIFQPISASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKPQYLSMID Sbjct: 241 TSGNIPPNYQYIFQPISASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKPQYLSMID 300 Query: 301 LLESVDYMVRNAPYRKYKPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIKKHRQ 360 LLESVDYMVRNAPYRKYKPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIKKHRQ Sbjct: 301 LLESVDYMVRNAPYRKYKPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIKKHRQ 360 Query: 361 LLKSYKIAYKNKLTQSKVSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKS 420 LLKSYKIAYKNKLTQSKVSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKS Sbjct: 361 LLKSYKIAYKNKLTQSKVSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKS 420 Query: 421 ADTGEKRGGWFSGLWGKKESKKKDEESLIPETIDDLMTPEEKDKLFTAIGYSESTHNLTL 480 ADTGEKRGGWFSGLWGKKESKKKDEESLIPETIDDLMTPEEKDKLFTAIGYSESTHNLTL Sbjct: 421 ADTGEKRGGWFSGLWGKKESKKKDEESLIPETIDDLMTPEEKDKLFTAIGYSESTHNLTL 480 Query: 481 PKQYVAHIMTLKLVSTSVTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVEAKLEHWY 540 PKQYVAHIMTLKLVSTSVTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVEAKLEHWY Sbjct: 481 PKQYVAHIMTLKLVSTSVTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVEAKLEHWY 540 Query: 541 ITGLRQQDIVPSLVASIGDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIYDAKTVNA 600 ITGLRQQDIVPSLVASIGDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIYDAKTVNA Sbjct: 541 ITGLRQQDIVPSLVASIGDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIYDAKTVNA 600 Query: 601 VVEFFQSNKGLDLEQITSATLMKLEEIKERTATGLTHIIETRKVLDLRINLKPSYLVVPQ 660 VVEFFQSNKGLDLEQITSATLMKLEEIKERTATGLTHIIETRKVLDLRINLKPSYLVVPQ Sbjct: 601 VVEFFQSNKGLDLEQITSATLMKLEEIKERTATGLTHIIETRKVLDLRINLKPSYLVVPQ 660 Query: 661 TGFHHEKSDLLILDFGTFQLNSKDQGLQKTTNSSLEEIMDKAYDKFDVEIKNVQLLFARA 720 TGFHHEKSDLLILDFGTFQLNSKDQGLQKTTNSSLEEIMDKAYDKFDVEIKNVQLLFARA Sbjct: 661 TGFHHEKSDLLILDFGTFQLNSKDQGLQKTTNSSLEEIMDKAYDKFDVEIKNVQLLFARA 720 Query: 721 EETWKKCRFQHPSTMHILQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVRISDQKMK 780 EETWKKCRFQHPSTMHILQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVRISDQKMK Sbjct: 721 EETWKKCRFQHPSTMHILQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVRISDQKMK 780 Query: 781 DVLYLMNSIPLPQKSSAQSPERQVSSIPIISGGTKGLLGTSLLLDTVESESDDEYFDAED 840 DVLYLMNSIPLPQKSSAQSPERQVSSIPIISGGTKGLLGTSLLLDTVESESDDEYFDAED Sbjct: 781 DVLYLMNSIPLPQKSSAQSPERQVSSIPIISGGTKGLLGTSLLLDTVESESDDEYFDAED 840 Query: 841 GEPQTCKSMKGSELKKAAEVPNEELINLLLKFEIKEVILEFTKQQKEEDTILVFNVTQLG 900 GEPQTCKSMKGSELKKAAEVPNEELINLLLKFEIKEVILEFTKQQKEEDTILVFNVTQLG Sbjct: 841 GEPQTCKSMKGSELKKAAEVPNEELINLLLKFEIKEVILEFTKQQKEEDTILVFNVTQLG 900 Query: 901 TEATMRTFDLTVVSYLKKISLDYHEIEGSKRKPLHLISSSDKPGLDLLKVEYIKADKNGP 960 TEATMRTFDLTVVSYLKKISLDYHEIEGSKRKPLHLISSSDKPGLDLLKVEYIKADKNGP Sbjct: 901 TEATMRTFDLTVVSYLKKISLDYHEIEGSKRKPLHLISSSDKPGLDLLKVEYIKADKNGP 960 Query: 961 SFQTAFGKTEQTVKVAFSSLNLLLQTQALVASINYLTTIIPSDDQSISVAKEVQISTEKQ 1020 SFQTAFGKTEQTVKVAFSSLNLLLQTQALVASINYLTTIIPSDDQSISVAKEVQISTEKQ Sbjct: 961 SFQTAFGKTEQTVKVAFSSLNLLLQTQALVASINYLTTIIPSDDQSISVAKEVQISTEKQ 1020 Query: 1021 QKNSTLPKAIVSSRDSDIIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSSLSLQSRKQ 1080 QKNSTLPKAIVSSRDSDIIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSSLSLQSRKQ Sbjct: 1021 QKNSTLPKAIVSSRDSDIIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSSLSLQSRKQ 1080 Query: 1081 SLFARLENIIVTDVDPKTVHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMSKVDGVLSL 1140 SLFARLENIIVTDVDPKTVHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMSKVDGVLSL Sbjct: 1081 SLFARLENIIVTDVDPKTVHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMSKVDGVLSL 1140 Query: 1141 NVGCIQIVYLHKFLMSLLNFLNNFQTAKESLSAATAQAAERAATSVKDLAQRSFRVSINI 1200 NVGCIQIVYLHKFLMSLLNFLNNFQTAKESLSAATAQAAERAATSVKDLAQRSFRVSINI Sbjct: 1141 NVGCIQIVYLHKFLMSLLNFLNNFQTAKESLSAATAQAAERAATSVKDLAQRSFRVSINI 1200 Query: 1201 DLKAPVIVIPQSSISTNAVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQLTKLTLYR 1260 DLKAPVIVIPQSSISTNAVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQLTKLTLYR Sbjct: 1201 DLKAPVIVIPQSSISTNAVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQLTKLTLYR 1260 Query: 1261 TVIQPGIYHPDIQLLHPINLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLNQEDLNLL 1320 TVIQPGIYHPDIQLLHPINLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLNQEDLNLL Sbjct: 1261 TVIQPGIYHPDIQLLHPINLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLNQEDLNLL 1320 Query: 1321 FRILTENLCEGTEDLDKVKPRVQETGEIKEPLEISISQDVHDSKNTLTTGVEEIRSVDII 1380 FRILTENLCEGTEDLDKVKPRVQETGEIKEPLEISISQDVHDSKNTLTTGVEEIRSVDII Sbjct: 1321 FRILTENLCEGTEDLDKVKPRVQETGEIKEPLEISISQDVHDSKNTLTTGVEEIRSVDII 1380 Query: 1381 NMLLNFEIKEVVVTLMKKSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFD 1440 NMLLNFEIKEVVVTLMKKSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFD Sbjct: 1381 NMLLNFEIKEVVVTLMKKSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFD 1440 Query: 1441 FTDSKGEPLHIINSSNVTDEPLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLH 1500 FTDSKGEPLHIINSSNVTDEPLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLH Sbjct: 1441 FTDSKGEPLHIINSSNVTDEPLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLH 1500 Query: 1501 LEALLSFMDFLSSAAPFSEPSSSEKESELKPLVGESRSIAVKAVSSNISQKDVFDLKITA 1560 LEALLSFMDFLSSAAPFSEPSSSEKESELKPLVGESRSIAVKAVSSNISQKDVFDLKITA Sbjct: 1501 LEALLSFMDFLSSAAPFSEPSSSEKESELKPLVGESRSIAVKAVSSNISQKDVFDLKITA 1560 Query: 1561 ELNAFNVFVCDQKCNIADIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQSIHKKAVS 1620 ELNAFNVFVCDQKCNIADIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQSIHKKAVS Sbjct: 1561 ELNAFNVFVCDQKCNIADIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQSIHKKAVS 1620 Query: 1621 ILGDEVFRFQLTLYPDATEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQ 1680 ILGDEVFRFQLTLYPDATEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQ Sbjct: 1621 ILGDEVFRFQLTLYPDATEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQ 1680 Query: 1681 TAKEALSTATVQAAERAASSMKDLAQKSFRLLMDINLKAPVIIIPQSSVSPNAVIADLGL 1740 TAKEALSTATVQAAERAASSMKDLAQKSFRLLMDINLKAPVIIIPQSSVSPNAVIADLGL Sbjct: 1681 TAKEALSTATVQAAERAASSMKDLAQKSFRLLMDINLKAPVIIIPQSSVSPNAVIADLGL 1740 Query: 1741 IRVENKFSLVPMEHYSLPPVIDKMNIELTQLKLSRTILQASLPQNDIEILKPVNMLLSIQ 1800 IRVENKFSLVPMEHYSLPPVIDKMNIELTQLKLSRTILQASLPQNDIEILKPVNMLLSIQ Sbjct: 1741 IRVENKFSLVPMEHYSLPPVIDKMNIELTQLKLSRTILQASLPQNDIEILKPVNMLLSIQ 1800 Query: 1801 RNLAAAWYVQIPGMEIKGKLKPMQVALSEDDLTVLMKILLENLGEASSQPSPTQSVQETV 1860 RNLAAAWYVQIPGMEIKGKLKPMQVALSEDDLTVLMKILLENLGEASSQPSPTQSVQETV Sbjct: 1801 RNLAAAWYVQIPGMEIKGKLKPMQVALSEDDLTVLMKILLENLGEASSQPSPTQSVQETV 1860 Query: 1861 RVRKVDVSSVPDHLKEQEDWTDSKLSMNQIVSLQFDFHFESLSIILYNNDINQESGVAFH 1920 RVRKVDVSSVPDHLKEQEDWTDSKLSMNQIVSLQFDFHFESLSIILYNNDINQESGVAFH Sbjct: 1861 RVRKVDVSSVPDHLKEQEDWTDSKLSMNQIVSLQFDFHFESLSIILYNNDINQESGVAFH 1920 Query: 1921 NDSFQLGELRLHLMASSGKMFKDGSMNVSVKLKTCTLDDLREGIERATSRMIDRKNDQDN 1980 NDSFQLGELRLHLMASSGKMFKDGSMNVSVKLKTCTLDDLREGIERATSRMIDRKNDQDN Sbjct: 1921 NDSFQLGELRLHLMASSGKMFKDGSMNVSVKLKTCTLDDLREGIERATSRMIDRKNDQDN 1980 Query: 1981 NSSMIDISYKQDKNGSQIDAVLDKLYVCASVEFLMTVADFFIKAVPQSPENVAKETQILP 2040 NSSMIDISYKQDKNGSQIDAVLDKLYVCASVEFLMTVADFFIKAVPQSPENVAKETQILP Sbjct: 1981 NSSMIDISYKQDKNGSQIDAVLDKLYVCASVEFLMTVADFFIKAVPQSPENVAKETQILP 2040 Query: 2041 RQTATGKVKIEKDDSVRPNMTLKAMITDPEVVFVASLTKADAPALTASFQCNLSLSTSKL 2100 RQTATGKVKIEKDDSVRPNMTLKAMITDPEVVFVASLTKADAPALTASFQCNLSLSTSKL Sbjct: 2041 RQTATGKVKIEKDDSVRPNMTLKAMITDPEVVFVASLTKADAPALTASFQCNLSLSTSKL 2100 Query: 2101 EQMMEASVRDLKVLACPFLREKRGKNITTVLQPCSLFMEKCTWASGKQNINIMVKEFIIK 2160 EQMMEASVRDLKVLACPFLREKRGKNITTVLQPCSLFMEKCTWASGKQNINIMVKEFIIK Sbjct: 2101 EQMMEASVRDLKVLACPFLREKRGKNITTVLQPCSLFMEKCTWASGKQNINIMVKEFIIK 2160 Query: 2161 ISPIILNTVLTIMAALSPKTKEDGSKDTSKEMENLWGIKSINDYNTWFLGVDTATEITES 2220 ISPIILNTVLTIMAALSPKTKEDGSKDTSKEMENLWGIKSINDYNTWFLGVDTATEITES Sbjct: 2161 ISPIILNTVLTIMAALSPKTKEDGSKDTSKEMENLWGIKSINDYNTWFLGVDTATEITES 2220 Query: 2221 FKGIEHSLIEENCGVVVESIQVTLECGLGHRTVPLLLAESKFSGNIKNWTSLMAAVADVT 2280 FKGIEHSLIEENCGVVVESIQVTLECGLGHRTVPLLLAESKFSGNIKNWTSLMAAVADVT Sbjct: 2221 FKGIEHSLIEENCGVVVESIQVTLECGLGHRTVPLLLAESKFSGNIKNWTSLMAAVADVT 2280 Query: 2281 LQVHYYNEIHAVWEPLIERVEGKRQWNLRLDVKKNPVQDKSLLPGDDFIPEPQMAIHISS 2340 LQVHYYNEIHAVWEPLIERVEGKRQWNLRLDVKKNPVQDKSLLPGDDFIPEPQMAIHISS Sbjct: 2281 LQVHYYNEIHAVWEPLIERVEGKRQWNLRLDVKKNPVQDKSLLPGDDFIPEPQMAIHISS 2340 Query: 2341 GNTMNITISKSCLNVFNNLAKGFSEGTASTFDYSLKDRAPFTVKNAVGVPIKVKPNCNLR 2400 GNTMNITISKSCLNVFNNLAKGFSEGTASTFDYSLKDRAPFTVKNAVGVPIKVKPNCNLR Sbjct: 2341 GNTMNITISKSCLNVFNNLAKGFSEGTASTFDYSLKDRAPFTVKNAVGVPIKVKPNCNLR 2400 Query: 2401 VMGFPEKSDIFDVDAGQNLELEYASMVPSSQGNLSILSRQESSFFTLTIVPHGYTEVANI 2460 VMGFPEKSDIFDVDAGQNLELEYASMVPSSQGNLSILSRQESSFFTLTIVPHGYTEVANI Sbjct: 2401 VMGFPEKSDIFDVDAGQNLELEYASMVPSSQGNLSILSRQESSFFTLTIVPHGYTEVANI 2460 Query: 2461 PVARPGRRLYNVRNPNASHSDSVLVQIDATEGNKVITLRSPLQIKNHFSIAFIIYKFVKN 2520 PVARPGRRLYNVRNPNASHSDSVLVQIDATEGNKVITLRSPLQIKNHFSIAFIIYKFVKN Sbjct: 2461 PVARPGRRLYNVRNPNASHSDSVLVQIDATEGNKVITLRSPLQIKNHFSIAFIIYKFVKN 2520 Query: 2521 VKLLERIGIARPEEEFHVPLDSYRCQLFIQPAGILEHQYKESTTYISWKEELHRSREVRC 2580 VKLLERIGIARPEEEFHVPLDSYRCQLFIQPAGILEHQYKESTTYISWKEELHRSREVRC Sbjct: 2521 VKLLERIGIARPEEEFHVPLDSYRCQLFIQPAGILEHQYKESTTYISWKEELHRSREVRC 2580 Query: 2581 MLQCPSVEVSFLPLIVNTVALPDELSYICTHGEDWDVAYIIHLYPSLTLRNLLPYSLRYL 2640 MLQCPSVEVSFLPLIVNTVALPDELSYICTHGEDWDVAYIIHLYPSLTLRNLLPYSLRYL Sbjct: 2581 MLQCPSVEVSFLPLIVNTVALPDELSYICTHGEDWDVAYIIHLYPSLTLRNLLPYSLRYL 2640 Query: 2641 LEGTAETHELAEGSTADVLHSRISGEIMELVLVKYQGKNWNGHFRIRDTLPEFFPVCFSS 2700 LEGTAETHELAEGSTADVLHSRISGEIMELVLVKYQGKNWNGHFRIRDTLPEFFPVCFSS Sbjct: 2641 LEGTAETHELAEGSTADVLHSRISGEIMELVLVKYQGKNWNGHFRIRDTLPEFFPVCFSS 2700 Query: 2701 DSTEVTTVDLSVHVRRIGSRMVLSVFSPYWLINKTTRVLQYRSEDIHVKHPADFRDIILF 2760 DSTEVTTVDLSVHVRRIGSRMVLSVFSPYWLINKTTRVLQYRSEDIHVKHPADFRDIILF Sbjct: 2701 DSTEVTTVDLSVHVRRIGSRMVLSVFSPYWLINKTTRVLQYRSEDIHVKHPADFRDIILF 2760 Query: 2761 SFKKKNIFTKNKVQLKISTSAWSSSFSLDTVGSYGCVKCPANNMEYLVGVSIKMSSFNLS 2820 SFKKKNIFTKNKVQLKISTSAWSSSFSLDTVGSYGCVKCPANNMEYLVGVSIKMSSFNLS Sbjct: 2761 SFKKKNIFTKNKVQLKISTSAWSSSFSLDTVGSYGCVKCPANNMEYLVGVSIKMSSFNLS 2820 Query: 2821 RIVTLTPFCTIANKSSLELEVGEIASDGSMPTNKWNYIASSECLPFWPESLSGKLCVRVV 2880 RIVTLTPFCTIANKSSLELEVGEIASDGSMPTNKWNYIASSECLPFWPESLSGKLCVRVV Sbjct: 2821 RIVTLTPFCTIANKSSLELEVGEIASDGSMPTNKWNYIASSECLPFWPESLSGKLCVRVV 2880 Query: 2881 GCEGSSKPFFYNRQDNGTLLSLEDLNGGILVDVNTAEHSTVITFSDYHEGSAPALIMNHT 2940 GCEGSSKPFFYNRQDNGTLLSLEDLNGGILVDVNTAEHSTVITFSDYHEGSAPALIMNHT Sbjct: 2881 GCEGSSKPFFYNRQDNGTLLSLEDLNGGILVDVNTAEHSTVITFSDYHEGSAPALIMNHT 2940 Query: 2941 PWDILTYKQSGSPEEMVLLPRQARLFAWADPTGTRKLTWTYAANVGEHDLLKDGCGQFPY 3000 PWDILTYKQSGSPEEMVLLPRQARLFAWADPTGTRKLTWTYAANVGEHDLLKDGCGQFPY Sbjct: 2941 PWDILTYKQSGSPEEMVLLPRQARLFAWADPTGTRKLTWTYAANVGEHDLLKDGCGQFPY 3000 Query: 3001 DANIQIHWVSFLDGRQRVLLFTDDVALVSKALQAEEMEQADYEITLSLHSLGLSLVNNES 3060 DANIQIHWVSFLDGRQRVLLFTDDVALVSKALQAEEMEQADYEITLSLHSLGLSLVNNES Sbjct: 3001 DANIQIHWVSFLDGRQRVLLFTDDVALVSKALQAEEMEQADYEITLSLHSLGLSLVNNES 3060 Query: 3061 KQEVSYIGITSSGVVWEVKPKQKWKPFSQKQIILLEQSYQKHQISRDHGWIKLDNNFEVN 3120 KQEVSYIGITSSGVVWEVKPKQKWKPFSQKQIILLEQSYQKHQISRDHGWIKLDNNFEVN Sbjct: 3061 KQEVSYIGITSSGVVWEVKPKQKWKPFSQKQIILLEQSYQKHQISRDHGWIKLDNNFEVN 3120 Query: 3121 FDKDPMEMRLPIRSPIKRDFLSGIQIEFKQSSHQRSLRARLYWLQVDNQLPGAMFPVVFH 3180 FDKDPMEMRLPIRSPIKRDFLSGIQIEFKQSSHQRSLRARLYWLQVDNQLPGAMFPVVFH Sbjct: 3121 FDKDPMEMRLPIRSPIKRDFLSGIQIEFKQSSHQRSLRARLYWLQVDNQLPGAMFPVVFH 3180 Query: 3181 PVAPPKSIALDSEPKPFIDVSVITRFNEYSKVLQFKYFMVLIQEMALKIDQGFLGAIIAL 3240 PVAPPKSIALDSEPKPFIDVSVITRFNEYSKVLQFKYFMVLIQEMALKIDQGFLGAIIAL Sbjct: 3181 PVAPPKSIALDSEPKPFIDVSVITRFNEYSKVLQFKYFMVLIQEMALKIDQGFLGAIIAL 3240 Query: 3241 FTPTTDPEAERRRTKLIQQDIDALNAELMETSMTDMSILSFFEHFHISPVKLHLSLSLGS 3300 FTPTTDPEAERRRTKLIQQDIDALNAELMETSMTDMSILSFFEHFHISPVKLHLSLSLGS Sbjct: 3241 FTPTTDPEAERRRTKLIQQDIDALNAELMETSMTDMSILSFFEHFHISPVKLHLSLSLGS 3300 Query: 3301 GGEESDKEKQEMFAVHSVNLLLKSIGATLTDVDDLIFKLAYYEIRYQFYKRDQLIWSVVR 3360 GGEESDKEKQEMFAVHSVNLLLKSIGATLTDVDDLIFKLAYYEIRYQFYKRDQLIWSVVR Sbjct: 3301 GGEESDKEKQEMFAVHSVNLLLKSIGATLTDVDDLIFKLAYYEIRYQFYKRDQLIWSVVR 3360 Query: 3361 HYSEQFLKQMYVLVLGLDVLGNPFGLIRGLSEGVEALFYEPFQGAVQGPEEFAEGLVIGV 3420 HYSEQFLKQMYVLVLGLDVLGNPFGLIRGLSEGVEALFYEPFQGAVQGPEEFAEGLVIGV Sbjct: 3361 HYSEQFLKQMYVLVLGLDVLGNPFGLIRGLSEGVEALFYEPFQGAVQGPEEFAEGLVIGV 3420 Query: 3421 RSLFGHTVGGAAGVVSRITGSVGKGLAAITMDKEYQQKRREELSRQPRDFGDSLARGGKG 3480 RSLFGHTVGGAAGVVSRITGSVGKGLAAITMDKEYQQKRREELSRQPRDFGDSLARGGKG Sbjct: 3421 RSLFGHTVGGAAGVVSRITGSVGKGLAAITMDKEYQQKRREELSRQPRDFGDSLARGGKG 3480 Query: 3481 FLRGVVGGVTGIITKPVEGAKKEGAAGFFKGIGKGLVGAVARPTGGIVDMASSTFQGIQR 3540 FLRGVVGGVTGIITKPVEGAKKEGAAGFFKGIGKGLVGAVARPTGGIVDMASSTFQGIQR Sbjct: 3481 FLRGVVGGVTGIITKPVEGAKKEGAAGFFKGIGKGLVGAVARPTGGIVDMASSTFQGIQR 3540 Query: 3541 AAESTEEVSSLRPPRLIHEDGIIRPYDRQESEGSDLLEQELEIQE 3585 AAESTEEVSSLRPPRLIHEDGIIRPYDRQESEGSDLLEQELEIQE Sbjct: 3541 AAESTEEVSSLRPPRLIHEDGIIRPYDRQESEGSDLLEQELEIQE 3585 >gi|42544121 vacuolar protein sorting 13C protein isoform 1A [Homo sapiens] Length = 3710 Score = 7016 bits (18204), Expect = 0.0 Identities = 3578/3582 (99%), Positives = 3580/3582 (99%) Query: 1 MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAG 60 MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAG Sbjct: 1 MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAG 60 Query: 61 QIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEE 120 QIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEE Sbjct: 61 QIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEE 120 Query: 121 ALQKAAEKDKPKEAKKDTFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLG 180 ALQKAAEKDKPKEAKKDTFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLG Sbjct: 121 ALQKAAEKDKPKEAKKDTFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLG 180 Query: 181 ELSLLTANEHWTPCILNEADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILDQLKNEIL 240 ELSLLTANEHWTPCILNEADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILDQLKNEIL Sbjct: 181 ELSLLTANEHWTPCILNEADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILDQLKNEIL 240 Query: 241 TSGNIPPNYQYIFQPISASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKPQYLSMID 300 TSGNIPPNYQYIFQPISASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKPQYLSMID Sbjct: 241 TSGNIPPNYQYIFQPISASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKPQYLSMID 300 Query: 301 LLESVDYMVRNAPYRKYKPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIKKHRQ 360 LLESVDYMVRNAPYRKYKPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIKKHRQ Sbjct: 301 LLESVDYMVRNAPYRKYKPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIKKHRQ 360 Query: 361 LLKSYKIAYKNKLTQSKVSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKS 420 LLKSYKIAYKNKLTQSKVSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKS Sbjct: 361 LLKSYKIAYKNKLTQSKVSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKS 420 Query: 421 ADTGEKRGGWFSGLWGKKESKKKDEESLIPETIDDLMTPEEKDKLFTAIGYSESTHNLTL 480 ADTGEKRGGWFSGLWGKKESKKKDEESLIPETIDDLMTPEEKDKLFTAIGYSESTHNLTL Sbjct: 421 ADTGEKRGGWFSGLWGKKESKKKDEESLIPETIDDLMTPEEKDKLFTAIGYSESTHNLTL 480 Query: 481 PKQYVAHIMTLKLVSTSVTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVEAKLEHWY 540 PKQYVAHIMTLKLVSTSVTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVEAKLEHWY Sbjct: 481 PKQYVAHIMTLKLVSTSVTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVEAKLEHWY 540 Query: 541 ITGLRQQDIVPSLVASIGDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIYDAKTVNA 600 ITGLRQQDIVPSLVASIGDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIYDAKTVNA Sbjct: 541 ITGLRQQDIVPSLVASIGDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIYDAKTVNA 600 Query: 601 VVEFFQSNKGLDLEQITSATLMKLEEIKERTATGLTHIIETRKVLDLRINLKPSYLVVPQ 660 VVEFFQSNKGLDLEQITSATLMKLEEIKERTATGLTHIIETRKVLDLRINLKPSYLVVPQ Sbjct: 601 VVEFFQSNKGLDLEQITSATLMKLEEIKERTATGLTHIIETRKVLDLRINLKPSYLVVPQ 660 Query: 661 TGFHHEKSDLLILDFGTFQLNSKDQGLQKTTNSSLEEIMDKAYDKFDVEIKNVQLLFARA 720 TGFHHEKSDLLILDFGTFQLNSKDQGLQKTTNSSLEEIMDKAYDKFDVEIKNVQLLFARA Sbjct: 661 TGFHHEKSDLLILDFGTFQLNSKDQGLQKTTNSSLEEIMDKAYDKFDVEIKNVQLLFARA 720 Query: 721 EETWKKCRFQHPSTMHILQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVRISDQKMK 780 EETWKKCRFQHPSTMHILQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVRISDQKMK Sbjct: 721 EETWKKCRFQHPSTMHILQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVRISDQKMK 780 Query: 781 DVLYLMNSIPLPQKSSAQSPERQVSSIPIISGGTKGLLGTSLLLDTVESESDDEYFDAED 840 DVLYLMNSIPLPQKSSAQSPERQVSSIPIISGGTKGLLGTSLLLDTVESESDDEYFDAED Sbjct: 781 DVLYLMNSIPLPQKSSAQSPERQVSSIPIISGGTKGLLGTSLLLDTVESESDDEYFDAED 840 Query: 841 GEPQTCKSMKGSELKKAAEVPNEELINLLLKFEIKEVILEFTKQQKEEDTILVFNVTQLG 900 GEPQTCKSMKGSELKKAAEVPNEELINLLLKFEIKEVILEFTKQQKEEDTILVFNVTQLG Sbjct: 841 GEPQTCKSMKGSELKKAAEVPNEELINLLLKFEIKEVILEFTKQQKEEDTILVFNVTQLG 900 Query: 901 TEATMRTFDLTVVSYLKKISLDYHEIEGSKRKPLHLISSSDKPGLDLLKVEYIKADKNGP 960 TEATMRTFDLTVVSYLKKISLDYHEIEGSKRKPLHLISSSDKPGLDLLKVEYIKADKNGP Sbjct: 901 TEATMRTFDLTVVSYLKKISLDYHEIEGSKRKPLHLISSSDKPGLDLLKVEYIKADKNGP 960 Query: 961 SFQTAFGKTEQTVKVAFSSLNLLLQTQALVASINYLTTIIPSDDQSISVAKEVQISTEKQ 1020 SFQTAFGKTEQTVKVAFSSLNLLLQTQALVASINYLTTIIPSDDQSISVAKEVQISTEKQ Sbjct: 961 SFQTAFGKTEQTVKVAFSSLNLLLQTQALVASINYLTTIIPSDDQSISVAKEVQISTEKQ 1020 Query: 1021 QKNSTLPKAIVSSRDSDIIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSSLSLQSRKQ 1080 QKNSTLPKAIVSSRDSDIIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSSLSLQSRKQ Sbjct: 1021 QKNSTLPKAIVSSRDSDIIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSSLSLQSRKQ 1080 Query: 1081 SLFARLENIIVTDVDPKTVHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMSKVDGVLSL 1140 SLFARLENIIVTDVDPKTVHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMSKVDGVLSL Sbjct: 1081 SLFARLENIIVTDVDPKTVHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMSKVDGVLSL 1140 Query: 1141 NVGCIQIVYLHKFLMSLLNFLNNFQTAKESLSAATAQAAERAATSVKDLAQRSFRVSINI 1200 NVGCIQIVYLHKFLMSLLNFLNNFQTAKESLSAATAQAAERAATSVKDLAQRSFRVSINI Sbjct: 1141 NVGCIQIVYLHKFLMSLLNFLNNFQTAKESLSAATAQAAERAATSVKDLAQRSFRVSINI 1200 Query: 1201 DLKAPVIVIPQSSISTNAVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQLTKLTLYR 1260 DLKAPVIVIPQSSISTNAVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQLTKLTLYR Sbjct: 1201 DLKAPVIVIPQSSISTNAVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQLTKLTLYR 1260 Query: 1261 TVIQPGIYHPDIQLLHPINLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLNQEDLNLL 1320 TVIQPGIYHPDIQLLHPINLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLNQEDLNLL Sbjct: 1261 TVIQPGIYHPDIQLLHPINLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLNQEDLNLL 1320 Query: 1321 FRILTENLCEGTEDLDKVKPRVQETGEIKEPLEISISQDVHDSKNTLTTGVEEIRSVDII 1380 FRILTENLCEGTEDLDKVKPRVQETGEIKEPLEISISQDVHDSKNTLTTGVEEIRSVDII Sbjct: 1321 FRILTENLCEGTEDLDKVKPRVQETGEIKEPLEISISQDVHDSKNTLTTGVEEIRSVDII 1380 Query: 1381 NMLLNFEIKEVVVTLMKKSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFD 1440 NMLLNFEIKEVVVTLMKKSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFD Sbjct: 1381 NMLLNFEIKEVVVTLMKKSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFD 1440 Query: 1441 FTDSKGEPLHIINSSNVTDEPLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLH 1500 FTDSKGEPLHIINSSNVTDEPLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLH Sbjct: 1441 FTDSKGEPLHIINSSNVTDEPLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLH 1500 Query: 1501 LEALLSFMDFLSSAAPFSEPSSSEKESELKPLVGESRSIAVKAVSSNISQKDVFDLKITA 1560 LEALLSFMDFLSSAAPFSEPSSSEKESELKPLVGESRSIAVKAVSSNISQKDVFDLKITA Sbjct: 1501 LEALLSFMDFLSSAAPFSEPSSSEKESELKPLVGESRSIAVKAVSSNISQKDVFDLKITA 1560 Query: 1561 ELNAFNVFVCDQKCNIADIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQSIHKKAVS 1620 ELNAFNVFVCDQKCNIADIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQSIHKKAVS Sbjct: 1561 ELNAFNVFVCDQKCNIADIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQSIHKKAVS 1620 Query: 1621 ILGDEVFRFQLTLYPDATEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQ 1680 ILGDEVFRFQLTLYPDATEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQ Sbjct: 1621 ILGDEVFRFQLTLYPDATEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQ 1680 Query: 1681 TAKEALSTATVQAAERAASSMKDLAQKSFRLLMDINLKAPVIIIPQSSVSPNAVIADLGL 1740 TAKEALSTATVQAAERAASSMKDLAQKSFRLLMDINLKAPVIIIPQSSVSPNAVIADLGL Sbjct: 1681 TAKEALSTATVQAAERAASSMKDLAQKSFRLLMDINLKAPVIIIPQSSVSPNAVIADLGL 1740 Query: 1741 IRVENKFSLVPMEHYSLPPVIDKMNIELTQLKLSRTILQASLPQNDIEILKPVNMLLSIQ 1800 IRVENKFSLVPMEHYSLPPVIDKMNIELTQLKLSRTILQASLPQNDIEILKPVNMLLSIQ Sbjct: 1741 IRVENKFSLVPMEHYSLPPVIDKMNIELTQLKLSRTILQASLPQNDIEILKPVNMLLSIQ 1800 Query: 1801 RNLAAAWYVQIPGMEIKGKLKPMQVALSEDDLTVLMKILLENLGEASSQPSPTQSVQETV 1860 RNLAAAWYVQIPGMEIKGKLKPMQVALSEDDLTVLMKILLENLGEASSQPSPTQSVQETV Sbjct: 1801 RNLAAAWYVQIPGMEIKGKLKPMQVALSEDDLTVLMKILLENLGEASSQPSPTQSVQETV 1860 Query: 1861 RVRKVDVSSVPDHLKEQEDWTDSKLSMNQIVSLQFDFHFESLSIILYNNDINQESGVAFH 1920 RVRKVDVSSVPDHLKEQEDWTDSKLSMNQIVSLQFDFHFESLSIILYNNDINQESGVAFH Sbjct: 1861 RVRKVDVSSVPDHLKEQEDWTDSKLSMNQIVSLQFDFHFESLSIILYNNDINQESGVAFH 1920 Query: 1921 NDSFQLGELRLHLMASSGKMFKDGSMNVSVKLKTCTLDDLREGIERATSRMIDRKNDQDN 1980 NDSFQLGELRLHLMASSGKMFKDGSMNVSVKLKTCTLDDLREGIERATSRMIDRKNDQDN Sbjct: 1921 NDSFQLGELRLHLMASSGKMFKDGSMNVSVKLKTCTLDDLREGIERATSRMIDRKNDQDN 1980 Query: 1981 NSSMIDISYKQDKNGSQIDAVLDKLYVCASVEFLMTVADFFIKAVPQSPENVAKETQILP 2040 NSSMIDISYKQDKNGSQIDAVLDKLYVCASVEFLMTVADFFIKAVPQSPENVAKETQILP Sbjct: 1981 NSSMIDISYKQDKNGSQIDAVLDKLYVCASVEFLMTVADFFIKAVPQSPENVAKETQILP 2040 Query: 2041 RQTATGKVKIEKDDSVRPNMTLKAMITDPEVVFVASLTKADAPALTASFQCNLSLSTSKL 2100 RQTATGKVKIEKDDSVRPNMTLKAMITDPEVVFVASLTKADAPALTASFQCNLSLSTSKL Sbjct: 2041 RQTATGKVKIEKDDSVRPNMTLKAMITDPEVVFVASLTKADAPALTASFQCNLSLSTSKL 2100 Query: 2101 EQMMEASVRDLKVLACPFLREKRGKNITTVLQPCSLFMEKCTWASGKQNINIMVKEFIIK 2160 EQMMEASVRDLKVLACPFLREKRGKNITTVLQPCSLFMEKCTWASGKQNINIMVKEFIIK Sbjct: 2101 EQMMEASVRDLKVLACPFLREKRGKNITTVLQPCSLFMEKCTWASGKQNINIMVKEFIIK 2160 Query: 2161 ISPIILNTVLTIMAALSPKTKEDGSKDTSKEMENLWGIKSINDYNTWFLGVDTATEITES 2220 ISPIILNTVLTIMAALSPKTKEDGSKDTSKEMENLWGIKSINDYNTWFLGVDTATEITES Sbjct: 2161 ISPIILNTVLTIMAALSPKTKEDGSKDTSKEMENLWGIKSINDYNTWFLGVDTATEITES 2220 Query: 2221 FKGIEHSLIEENCGVVVESIQVTLECGLGHRTVPLLLAESKFSGNIKNWTSLMAAVADVT 2280 FKGIEHSLIEENCGVVVESIQVTLECGLGHRTVPLLLAESKFSGNIKNWTSLMAAVADVT Sbjct: 2221 FKGIEHSLIEENCGVVVESIQVTLECGLGHRTVPLLLAESKFSGNIKNWTSLMAAVADVT 2280 Query: 2281 LQVHYYNEIHAVWEPLIERVEGKRQWNLRLDVKKNPVQDKSLLPGDDFIPEPQMAIHISS 2340 LQVHYYNEIHAVWEPLIERVEGKRQWNLRLDVKKNPVQDKSLLPGDDFIPEPQMAIHISS Sbjct: 2281 LQVHYYNEIHAVWEPLIERVEGKRQWNLRLDVKKNPVQDKSLLPGDDFIPEPQMAIHISS 2340 Query: 2341 GNTMNITISKSCLNVFNNLAKGFSEGTASTFDYSLKDRAPFTVKNAVGVPIKVKPNCNLR 2400 GNTMNITISKSCLNVFNNLAKGFSEGTASTFDYSLKDRAPFTVKNAVGVPIKVKPNCNLR Sbjct: 2341 GNTMNITISKSCLNVFNNLAKGFSEGTASTFDYSLKDRAPFTVKNAVGVPIKVKPNCNLR 2400 Query: 2401 VMGFPEKSDIFDVDAGQNLELEYASMVPSSQGNLSILSRQESSFFTLTIVPHGYTEVANI 2460 VMGFPEKSDIFDVDAGQNLELEYASMVPSSQGNLSILSRQESSFFTLTIVPHGYTEVANI Sbjct: 2401 VMGFPEKSDIFDVDAGQNLELEYASMVPSSQGNLSILSRQESSFFTLTIVPHGYTEVANI 2460 Query: 2461 PVARPGRRLYNVRNPNASHSDSVLVQIDATEGNKVITLRSPLQIKNHFSIAFIIYKFVKN 2520 PVARPGRRLYNVRNPNASHSDSVLVQIDATEGNKVITLRSPLQIKNHFSIAFIIYKFVKN Sbjct: 2461 PVARPGRRLYNVRNPNASHSDSVLVQIDATEGNKVITLRSPLQIKNHFSIAFIIYKFVKN 2520 Query: 2521 VKLLERIGIARPEEEFHVPLDSYRCQLFIQPAGILEHQYKESTTYISWKEELHRSREVRC 2580 VKLLERIGIARPEEEFHVPLDSYRCQLFIQPAGILEHQYKESTTYISWKEELHRSREVRC Sbjct: 2521 VKLLERIGIARPEEEFHVPLDSYRCQLFIQPAGILEHQYKESTTYISWKEELHRSREVRC 2580 Query: 2581 MLQCPSVEVSFLPLIVNTVALPDELSYICTHGEDWDVAYIIHLYPSLTLRNLLPYSLRYL 2640 MLQCPSVEVSFLPLIVNTVALPDELSYICTHGEDWDVAYIIHLYPSLTLRNLLPYSLRYL Sbjct: 2581 MLQCPSVEVSFLPLIVNTVALPDELSYICTHGEDWDVAYIIHLYPSLTLRNLLPYSLRYL 2640 Query: 2641 LEGTAETHELAEGSTADVLHSRISGEIMELVLVKYQGKNWNGHFRIRDTLPEFFPVCFSS 2700 LEGTAETHELAEGSTADVLHSRISGEIMELVLVKYQGKNWNGHFRIRDTLPEFFPVCFSS Sbjct: 2641 LEGTAETHELAEGSTADVLHSRISGEIMELVLVKYQGKNWNGHFRIRDTLPEFFPVCFSS 2700 Query: 2701 DSTEVTTVDLSVHVRRIGSRMVLSVFSPYWLINKTTRVLQYRSEDIHVKHPADFRDIILF 2760 DSTEVTTVDLSVHVRRIGSRMVLSVFSPYWLINKTTRVLQYRSEDIHVKHPADFRDIILF Sbjct: 2701 DSTEVTTVDLSVHVRRIGSRMVLSVFSPYWLINKTTRVLQYRSEDIHVKHPADFRDIILF 2760 Query: 2761 SFKKKNIFTKNKVQLKISTSAWSSSFSLDTVGSYGCVKCPANNMEYLVGVSIKMSSFNLS 2820 SFKKKNIFTKNKVQLKISTSAWSSSFSLDTVGSYGCVKCPANNMEYLVGVSIKMSSFNLS Sbjct: 2761 SFKKKNIFTKNKVQLKISTSAWSSSFSLDTVGSYGCVKCPANNMEYLVGVSIKMSSFNLS 2820 Query: 2821 RIVTLTPFCTIANKSSLELEVGEIASDGSMPTNKWNYIASSECLPFWPESLSGKLCVRVV 2880 RIVTLTPFCTIANKSSLELEVGEIASDGSMPTNKWNYIASSECLPFWPESLSGKLCVRVV Sbjct: 2821 RIVTLTPFCTIANKSSLELEVGEIASDGSMPTNKWNYIASSECLPFWPESLSGKLCVRVV 2880 Query: 2881 GCEGSSKPFFYNRQDNGTLLSLEDLNGGILVDVNTAEHSTVITFSDYHEGSAPALIMNHT 2940 GCEGSSKPFFYNRQDNGTLLSLEDLNGGILVDVNTAEHSTVITFSDYHEGSAPALIMNHT Sbjct: 2881 GCEGSSKPFFYNRQDNGTLLSLEDLNGGILVDVNTAEHSTVITFSDYHEGSAPALIMNHT 2940 Query: 2941 PWDILTYKQSGSPEEMVLLPRQARLFAWADPTGTRKLTWTYAANVGEHDLLKDGCGQFPY 3000 PWDILTYKQSGSPEEMVLLPRQARLFAWADPTGTRKLTWTYAANVGEHDLLKDGCGQFPY Sbjct: 2941 PWDILTYKQSGSPEEMVLLPRQARLFAWADPTGTRKLTWTYAANVGEHDLLKDGCGQFPY 3000 Query: 3001 DANIQIHWVSFLDGRQRVLLFTDDVALVSKALQAEEMEQADYEITLSLHSLGLSLVNNES 3060 DANIQIHWVSFLDGRQRVLLFTDDVALVSKALQAEEMEQADYEITLSLHSLGLSLVNNES Sbjct: 3001 DANIQIHWVSFLDGRQRVLLFTDDVALVSKALQAEEMEQADYEITLSLHSLGLSLVNNES 3060 Query: 3061 KQEVSYIGITSSGVVWEVKPKQKWKPFSQKQIILLEQSYQKHQISRDHGWIKLDNNFEVN 3120 KQEVSYIGITSSGVVWEVKPKQKWKPFSQKQIILLEQSYQKHQISRDHGWIKLDNNFEVN Sbjct: 3061 KQEVSYIGITSSGVVWEVKPKQKWKPFSQKQIILLEQSYQKHQISRDHGWIKLDNNFEVN 3120 Query: 3121 FDKDPMEMRLPIRSPIKRDFLSGIQIEFKQSSHQRSLRARLYWLQVDNQLPGAMFPVVFH 3180 FDKDPMEMRLPIRSPIKRDFLSGIQIEFKQSSHQRSLRARLYWLQVDNQLPGAMFPVVFH Sbjct: 3121 FDKDPMEMRLPIRSPIKRDFLSGIQIEFKQSSHQRSLRARLYWLQVDNQLPGAMFPVVFH 3180 Query: 3181 PVAPPKSIALDSEPKPFIDVSVITRFNEYSKVLQFKYFMVLIQEMALKIDQGFLGAIIAL 3240 PVAPPKSIALDSEPKPFIDVSVITRFNEYSKVLQFKYFMVLIQEMALKIDQGFLGAIIAL Sbjct: 3181 PVAPPKSIALDSEPKPFIDVSVITRFNEYSKVLQFKYFMVLIQEMALKIDQGFLGAIIAL 3240 Query: 3241 FTPTTDPEAERRRTKLIQQDIDALNAELMETSMTDMSILSFFEHFHISPVKLHLSLSLGS 3300 FTPTTDPEAERRRTKLIQQDIDALNAELMETSMTDMSILSFFEHFHISPVKLHLSLSLGS Sbjct: 3241 FTPTTDPEAERRRTKLIQQDIDALNAELMETSMTDMSILSFFEHFHISPVKLHLSLSLGS 3300 Query: 3301 GGEESDKEKQEMFAVHSVNLLLKSIGATLTDVDDLIFKLAYYEIRYQFYKRDQLIWSVVR 3360 GGEESDKEKQEMFAVHSVNLLLKSIGATLTDVDDLIFKLAYYEIRYQFYKRDQLIWSVVR Sbjct: 3301 GGEESDKEKQEMFAVHSVNLLLKSIGATLTDVDDLIFKLAYYEIRYQFYKRDQLIWSVVR 3360 Query: 3361 HYSEQFLKQMYVLVLGLDVLGNPFGLIRGLSEGVEALFYEPFQGAVQGPEEFAEGLVIGV 3420 HYSEQFLKQMYVLVLGLDVLGNPFGLIRGLSEGVEALFYEPFQGAVQGPEEFAEGLVIGV Sbjct: 3361 HYSEQFLKQMYVLVLGLDVLGNPFGLIRGLSEGVEALFYEPFQGAVQGPEEFAEGLVIGV 3420 Query: 3421 RSLFGHTVGGAAGVVSRITGSVGKGLAAITMDKEYQQKRREELSRQPRDFGDSLARGGKG 3480 RSLFGHTVGGAAGVVSRITGSVGKGLAAITMDKEYQQKRREELSRQPRDFGDSLARGGKG Sbjct: 3421 RSLFGHTVGGAAGVVSRITGSVGKGLAAITMDKEYQQKRREELSRQPRDFGDSLARGGKG 3480 Query: 3481 FLRGVVGGVTGIITKPVEGAKKEGAAGFFKGIGKGLVGAVARPTGGIVDMASSTFQGIQR 3540 FLRGVVGGVTGIITKPVEGAKKEGAAGFFKGIGKGLVGAVARPTGGIVDMASSTFQGIQR Sbjct: 3481 FLRGVVGGVTGIITKPVEGAKKEGAAGFFKGIGKGLVGAVARPTGGIVDMASSTFQGIQR 3540 Query: 3541 AAESTEEVSSLRPPRLIHEDGIIRPYDRQESEGSDLLEQELE 3582 AAESTEEVSSLRPPRLIHEDGIIRPYDRQESEGSDLLE ++ Sbjct: 3541 AAESTEEVSSLRPPRLIHEDGIIRPYDRQESEGSDLLENHIK 3582 >gi|66347845 vacuolar protein sorting 13C protein isoform 2B [Homo sapiens] Length = 3628 Score = 7007 bits (18180), Expect = 0.0 Identities = 3585/3628 (98%), Positives = 3585/3628 (98%), Gaps = 43/3628 (1%) Query: 1 MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAG 60 MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAG Sbjct: 1 MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAG 60 Query: 61 QIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEE 120 QIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEE Sbjct: 61 QIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEE 120 Query: 121 ALQKAAEK-------------------------------------------DKPKEAKKD 137 ALQKAAEK DKPKEAKKD Sbjct: 121 ALQKAAEKGTHSGEFIYGLENFVYKDIKPGRKRKKHKKHFKKPFKGLDRSKDKPKEAKKD 180 Query: 138 TFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLGELSLLTANEHWTPCILN 197 TFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLGELSLLTANEHWTPCILN Sbjct: 181 TFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLGELSLLTANEHWTPCILN 240 Query: 198 EADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILDQLKNEILTSGNIPPNYQYIFQPIS 257 EADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILDQLKNEILTSGNIPPNYQYIFQPIS Sbjct: 241 EADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILDQLKNEILTSGNIPPNYQYIFQPIS 300 Query: 258 ASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKPQYLSMIDLLESVDYMVRNAPYRKY 317 ASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKPQYLSMIDLLESVDYMVRNAPYRKY Sbjct: 301 ASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKPQYLSMIDLLESVDYMVRNAPYRKY 360 Query: 318 KPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIKKHRQLLKSYKIAYKNKLTQSK 377 KPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIKKHRQLLKSYKIAYKNKLTQSK Sbjct: 361 KPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIKKHRQLLKSYKIAYKNKLTQSK 420 Query: 378 VSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKSADTGEKRGGWFSGLWGK 437 VSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKSADTGEKRGGWFSGLWGK Sbjct: 421 VSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKSADTGEKRGGWFSGLWGK 480 Query: 438 KESKKKDEESLIPETIDDLMTPEEKDKLFTAIGYSESTHNLTLPKQYVAHIMTLKLVSTS 497 KESKKKDEESLIPETIDDLMTPEEKDKLFTAIGYSESTHNLTLPKQYVAHIMTLKLVSTS Sbjct: 481 KESKKKDEESLIPETIDDLMTPEEKDKLFTAIGYSESTHNLTLPKQYVAHIMTLKLVSTS 540 Query: 498 VTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVEAKLEHWYITGLRQQDIVPSLVASI 557 VTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVEAKLEHWYITGLRQQDIVPSLVASI Sbjct: 541 VTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVEAKLEHWYITGLRQQDIVPSLVASI 600 Query: 558 GDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIYDAKTVNAVVEFFQSNKGLDLEQIT 617 GDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIYDAKTVNAVVEFFQSNKGLDLEQIT Sbjct: 601 GDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIYDAKTVNAVVEFFQSNKGLDLEQIT 660 Query: 618 SATLMKLEEIKERTATGLTHIIETRKVLDLRINLKPSYLVVPQTGFHHEKSDLLILDFGT 677 SATLMKLEEIKERTATGLTHIIETRKVLDLRINLKPSYLVVPQTGFHHEKSDLLILDFGT Sbjct: 661 SATLMKLEEIKERTATGLTHIIETRKVLDLRINLKPSYLVVPQTGFHHEKSDLLILDFGT 720 Query: 678 FQLNSKDQGLQKTTNSSLEEIMDKAYDKFDVEIKNVQLLFARAEETWKKCRFQHPSTMHI 737 FQLNSKDQGLQKTTNSSLEEIMDKAYDKFDVEIKNVQLLFARAEETWKKCRFQHPSTMHI Sbjct: 721 FQLNSKDQGLQKTTNSSLEEIMDKAYDKFDVEIKNVQLLFARAEETWKKCRFQHPSTMHI 780 Query: 738 LQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVRISDQKMKDVLYLMNSIPLPQKSSA 797 LQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVRISDQKMKDVLYLMNSIPLPQKSSA Sbjct: 781 LQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVRISDQKMKDVLYLMNSIPLPQKSSA 840 Query: 798 QSPERQVSSIPIISGGTKGLLGTSLLLDTVESESDDEYFDAEDGEPQTCKSMKGSELKKA 857 QSPERQVSSIPIISGGTKGLLGTSLLLDTVESESDDEYFDAEDGEPQTCKSMKGSELKKA Sbjct: 841 QSPERQVSSIPIISGGTKGLLGTSLLLDTVESESDDEYFDAEDGEPQTCKSMKGSELKKA 900 Query: 858 AEVPNEELINLLLKFEIKEVILEFTKQQKEEDTILVFNVTQLGTEATMRTFDLTVVSYLK 917 AEVPNEELINLLLKFEIKEVILEFTKQQKEEDTILVFNVTQLGTEATMRTFDLTVVSYLK Sbjct: 901 AEVPNEELINLLLKFEIKEVILEFTKQQKEEDTILVFNVTQLGTEATMRTFDLTVVSYLK 960 Query: 918 KISLDYHEIEGSKRKPLHLISSSDKPGLDLLKVEYIKADKNGPSFQTAFGKTEQTVKVAF 977 KISLDYHEIEGSKRKPLHLISSSDKPGLDLLKVEYIKADKNGPSFQTAFGKTEQTVKVAF Sbjct: 961 KISLDYHEIEGSKRKPLHLISSSDKPGLDLLKVEYIKADKNGPSFQTAFGKTEQTVKVAF 1020 Query: 978 SSLNLLLQTQALVASINYLTTIIPSDDQSISVAKEVQISTEKQQKNSTLPKAIVSSRDSD 1037 SSLNLLLQTQALVASINYLTTIIPSDDQSISVAKEVQISTEKQQKNSTLPKAIVSSRDSD Sbjct: 1021 SSLNLLLQTQALVASINYLTTIIPSDDQSISVAKEVQISTEKQQKNSTLPKAIVSSRDSD 1080 Query: 1038 IIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSSLSLQSRKQSLFARLENIIVTDVDPK 1097 IIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSSLSLQSRKQSLFARLENIIVTDVDPK Sbjct: 1081 IIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSSLSLQSRKQSLFARLENIIVTDVDPK 1140 Query: 1098 TVHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMSKVDGVLSLNVGCIQIVYLHKFLMSL 1157 TVHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMSKVDGVLSLNVGCIQIVYLHKFLMSL Sbjct: 1141 TVHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMSKVDGVLSLNVGCIQIVYLHKFLMSL 1200 Query: 1158 LNFLNNFQTAKESLSAATAQAAERAATSVKDLAQRSFRVSINIDLKAPVIVIPQSSISTN 1217 LNFLNNFQTAKESLSAATAQAAERAATSVKDLAQRSFRVSINIDLKAPVIVIPQSSISTN Sbjct: 1201 LNFLNNFQTAKESLSAATAQAAERAATSVKDLAQRSFRVSINIDLKAPVIVIPQSSISTN 1260 Query: 1218 AVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQLTKLTLYRTVIQPGIYHPDIQLLHP 1277 AVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQLTKLTLYRTVIQPGIYHPDIQLLHP Sbjct: 1261 AVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQLTKLTLYRTVIQPGIYHPDIQLLHP 1320 Query: 1278 INLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLNQEDLNLLFRILTENLCEGTEDLDK 1337 INLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLNQEDLNLLFRILTENLCEGTEDLDK Sbjct: 1321 INLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLNQEDLNLLFRILTENLCEGTEDLDK 1380 Query: 1338 VKPRVQETGEIKEPLEISISQDVHDSKNTLTTGVEEIRSVDIINMLLNFEIKEVVVTLMK 1397 VKPRVQETGEIKEPLEISISQDVHDSKNTLTTGVEEIRSVDIINMLLNFEIKEVVVTLMK Sbjct: 1381 VKPRVQETGEIKEPLEISISQDVHDSKNTLTTGVEEIRSVDIINMLLNFEIKEVVVTLMK 1440 Query: 1398 KSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFDFTDSKGEPLHIINSSNV 1457 KSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFDFTDSKGEPLHIINSSNV Sbjct: 1441 KSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFDFTDSKGEPLHIINSSNV 1500 Query: 1458 TDEPLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLHLEALLSFMDFLSSAAPF 1517 TDEPLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLHLEALLSFMDFLSSAAPF Sbjct: 1501 TDEPLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLHLEALLSFMDFLSSAAPF 1560 Query: 1518 SEPSSSEKESELKPLVGESRSIAVKAVSSNISQKDVFDLKITAELNAFNVFVCDQKCNIA 1577 SEPSSSEKESELKPLVGESRSIAVKAVSSNISQKDVFDLKITAELNAFNVFVCDQKCNIA Sbjct: 1561 SEPSSSEKESELKPLVGESRSIAVKAVSSNISQKDVFDLKITAELNAFNVFVCDQKCNIA 1620 Query: 1578 DIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQSIHKKAVSILGDEVFRFQLTLYPDA 1637 DIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQSIHKKAVSILGDEVFRFQLTLYPDA Sbjct: 1621 DIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQSIHKKAVSILGDEVFRFQLTLYPDA 1680 Query: 1638 TEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQTAKEALSTATVQAAERA 1697 TEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQTAKEALSTATVQAAERA Sbjct: 1681 TEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQTAKEALSTATVQAAERA 1740 Query: 1698 ASSMKDLAQKSFRLLMDINLKAPVIIIPQSSVSPNAVIADLGLIRVENKFSLVPMEHYSL 1757 ASSMKDLAQKSFRLLMDINLKAPVIIIPQSSVSPNAVIADLGLIRVENKFSLVPMEHYSL Sbjct: 1741 ASSMKDLAQKSFRLLMDINLKAPVIIIPQSSVSPNAVIADLGLIRVENKFSLVPMEHYSL 1800 Query: 1758 PPVIDKMNIELTQLKLSRTILQASLPQNDIEILKPVNMLLSIQRNLAAAWYVQIPGMEIK 1817 PPVIDKMNIELTQLKLSRTILQASLPQNDIEILKPVNMLLSIQRNLAAAWYVQIPGMEIK Sbjct: 1801 PPVIDKMNIELTQLKLSRTILQASLPQNDIEILKPVNMLLSIQRNLAAAWYVQIPGMEIK 1860 Query: 1818 GKLKPMQVALSEDDLTVLMKILLENLGEASSQPSPTQSVQETVRVRKVDVSSVPDHLKEQ 1877 GKLKPMQVALSEDDLTVLMKILLENLGEASSQPSPTQSVQETVRVRKVDVSSVPDHLKEQ Sbjct: 1861 GKLKPMQVALSEDDLTVLMKILLENLGEASSQPSPTQSVQETVRVRKVDVSSVPDHLKEQ 1920 Query: 1878 EDWTDSKLSMNQIVSLQFDFHFESLSIILYNNDINQESGVAFHNDSFQLGELRLHLMASS 1937 EDWTDSKLSMNQIVSLQFDFHFESLSIILYNNDINQESGVAFHNDSFQLGELRLHLMASS Sbjct: 1921 EDWTDSKLSMNQIVSLQFDFHFESLSIILYNNDINQESGVAFHNDSFQLGELRLHLMASS 1980 Query: 1938 GKMFKDGSMNVSVKLKTCTLDDLREGIERATSRMIDRKNDQDNNSSMIDISYKQDKNGSQ 1997 GKMFKDGSMNVSVKLKTCTLDDLREGIERATSRMIDRKNDQDNNSSMIDISYKQDKNGSQ Sbjct: 1981 GKMFKDGSMNVSVKLKTCTLDDLREGIERATSRMIDRKNDQDNNSSMIDISYKQDKNGSQ 2040 Query: 1998 IDAVLDKLYVCASVEFLMTVADFFIKAVPQSPENVAKETQILPRQTATGKVKIEKDDSVR 2057 IDAVLDKLYVCASVEFLMTVADFFIKAVPQSPENVAKETQILPRQTATGKVKIEKDDSVR Sbjct: 2041 IDAVLDKLYVCASVEFLMTVADFFIKAVPQSPENVAKETQILPRQTATGKVKIEKDDSVR 2100 Query: 2058 PNMTLKAMITDPEVVFVASLTKADAPALTASFQCNLSLSTSKLEQMMEASVRDLKVLACP 2117 PNMTLKAMITDPEVVFVASLTKADAPALTASFQCNLSLSTSKLEQMMEASVRDLKVLACP Sbjct: 2101 PNMTLKAMITDPEVVFVASLTKADAPALTASFQCNLSLSTSKLEQMMEASVRDLKVLACP 2160 Query: 2118 FLREKRGKNITTVLQPCSLFMEKCTWASGKQNINIMVKEFIIKISPIILNTVLTIMAALS 2177 FLREKRGKNITTVLQPCSLFMEKCTWASGKQNINIMVKEFIIKISPIILNTVLTIMAALS Sbjct: 2161 FLREKRGKNITTVLQPCSLFMEKCTWASGKQNINIMVKEFIIKISPIILNTVLTIMAALS 2220 Query: 2178 PKTKEDGSKDTSKEMENLWGIKSINDYNTWFLGVDTATEITESFKGIEHSLIEENCGVVV 2237 PKTKEDGSKDTSKEMENLWGIKSINDYNTWFLGVDTATEITESFKGIEHSLIEENCGVVV Sbjct: 2221 PKTKEDGSKDTSKEMENLWGIKSINDYNTWFLGVDTATEITESFKGIEHSLIEENCGVVV 2280 Query: 2238 ESIQVTLECGLGHRTVPLLLAESKFSGNIKNWTSLMAAVADVTLQVHYYNEIHAVWEPLI 2297 ESIQVTLECGLGHRTVPLLLAESKFSGNIKNWTSLMAAVADVTLQVHYYNEIHAVWEPLI Sbjct: 2281 ESIQVTLECGLGHRTVPLLLAESKFSGNIKNWTSLMAAVADVTLQVHYYNEIHAVWEPLI 2340 Query: 2298 ERVEGKRQWNLRLDVKKNPVQDKSLLPGDDFIPEPQMAIHISSGNTMNITISKSCLNVFN 2357 ERVEGKRQWNLRLDVKKNPVQDKSLLPGDDFIPEPQMAIHISSGNTMNITISKSCLNVFN Sbjct: 2341 ERVEGKRQWNLRLDVKKNPVQDKSLLPGDDFIPEPQMAIHISSGNTMNITISKSCLNVFN 2400 Query: 2358 NLAKGFSEGTASTFDYSLKDRAPFTVKNAVGVPIKVKPNCNLRVMGFPEKSDIFDVDAGQ 2417 NLAKGFSEGTASTFDYSLKDRAPFTVKNAVGVPIKVKPNCNLRVMGFPEKSDIFDVDAGQ Sbjct: 2401 NLAKGFSEGTASTFDYSLKDRAPFTVKNAVGVPIKVKPNCNLRVMGFPEKSDIFDVDAGQ 2460 Query: 2418 NLELEYASMVPSSQGNLSILSRQESSFFTLTIVPHGYTEVANIPVARPGRRLYNVRNPNA 2477 NLELEYASMVPSSQGNLSILSRQESSFFTLTIVPHGYTEVANIPVARPGRRLYNVRNPNA Sbjct: 2461 NLELEYASMVPSSQGNLSILSRQESSFFTLTIVPHGYTEVANIPVARPGRRLYNVRNPNA 2520 Query: 2478 SHSDSVLVQIDATEGNKVITLRSPLQIKNHFSIAFIIYKFVKNVKLLERIGIARPEEEFH 2537 SHSDSVLVQIDATEGNKVITLRSPLQIKNHFSIAFIIYKFVKNVKLLERIGIARPEEEFH Sbjct: 2521 SHSDSVLVQIDATEGNKVITLRSPLQIKNHFSIAFIIYKFVKNVKLLERIGIARPEEEFH 2580 Query: 2538 VPLDSYRCQLFIQPAGILEHQYKESTTYISWKEELHRSREVRCMLQCPSVEVSFLPLIVN 2597 VPLDSYRCQLFIQPAGILEHQYKESTTYISWKEELHRSREVRCMLQCPSVEVSFLPLIVN Sbjct: 2581 VPLDSYRCQLFIQPAGILEHQYKESTTYISWKEELHRSREVRCMLQCPSVEVSFLPLIVN 2640 Query: 2598 TVALPDELSYICTHGEDWDVAYIIHLYPSLTLRNLLPYSLRYLLEGTAETHELAEGSTAD 2657 TVALPDELSYICTHGEDWDVAYIIHLYPSLTLRNLLPYSLRYLLEGTAETHELAEGSTAD Sbjct: 2641 TVALPDELSYICTHGEDWDVAYIIHLYPSLTLRNLLPYSLRYLLEGTAETHELAEGSTAD 2700 Query: 2658 VLHSRISGEIMELVLVKYQGKNWNGHFRIRDTLPEFFPVCFSSDSTEVTTVDLSVHVRRI 2717 VLHSRISGEIMELVLVKYQGKNWNGHFRIRDTLPEFFPVCFSSDSTEVTTVDLSVHVRRI Sbjct: 2701 VLHSRISGEIMELVLVKYQGKNWNGHFRIRDTLPEFFPVCFSSDSTEVTTVDLSVHVRRI 2760 Query: 2718 GSRMVLSVFSPYWLINKTTRVLQYRSEDIHVKHPADFRDIILFSFKKKNIFTKNKVQLKI 2777 GSRMVLSVFSPYWLINKTTRVLQYRSEDIHVKHPADFRDIILFSFKKKNIFTKNKVQLKI Sbjct: 2761 GSRMVLSVFSPYWLINKTTRVLQYRSEDIHVKHPADFRDIILFSFKKKNIFTKNKVQLKI 2820 Query: 2778 STSAWSSSFSLDTVGSYGCVKCPANNMEYLVGVSIKMSSFNLSRIVTLTPFCTIANKSSL 2837 STSAWSSSFSLDTVGSYGCVKCPANNMEYLVGVSIKMSSFNLSRIVTLTPFCTIANKSSL Sbjct: 2821 STSAWSSSFSLDTVGSYGCVKCPANNMEYLVGVSIKMSSFNLSRIVTLTPFCTIANKSSL 2880 Query: 2838 ELEVGEIASDGSMPTNKWNYIASSECLPFWPESLSGKLCVRVVGCEGSSKPFFYNRQDNG 2897 ELEVGEIASDGSMPTNKWNYIASSECLPFWPESLSGKLCVRVVGCEGSSKPFFYNRQDNG Sbjct: 2881 ELEVGEIASDGSMPTNKWNYIASSECLPFWPESLSGKLCVRVVGCEGSSKPFFYNRQDNG 2940 Query: 2898 TLLSLEDLNGGILVDVNTAEHSTVITFSDYHEGSAPALIMNHTPWDILTYKQSGSPEEMV 2957 TLLSLEDLNGGILVDVNTAEHSTVITFSDYHEGSAPALIMNHTPWDILTYKQSGSPEEMV Sbjct: 2941 TLLSLEDLNGGILVDVNTAEHSTVITFSDYHEGSAPALIMNHTPWDILTYKQSGSPEEMV 3000 Query: 2958 LLPRQARLFAWADPTGTRKLTWTYAANVGEHDLLKDGCGQFPYDANIQIHWVSFLDGRQR 3017 LLPRQARLFAWADPTGTRKLTWTYAANVGEHDLLKDGCGQFPYDANIQIHWVSFLDGRQR Sbjct: 3001 LLPRQARLFAWADPTGTRKLTWTYAANVGEHDLLKDGCGQFPYDANIQIHWVSFLDGRQR 3060 Query: 3018 VLLFTDDVALVSKALQAEEMEQADYEITLSLHSLGLSLVNNESKQEVSYIGITSSGVVWE 3077 VLLFTDDVALVSKALQAEEMEQADYEITLSLHSLGLSLVNNESKQEVSYIGITSSGVVWE Sbjct: 3061 VLLFTDDVALVSKALQAEEMEQADYEITLSLHSLGLSLVNNESKQEVSYIGITSSGVVWE 3120 Query: 3078 VKPKQKWKPFSQKQIILLEQSYQKHQISRDHGWIKLDNNFEVNFDKDPMEMRLPIRSPIK 3137 VKPKQKWKPFSQKQIILLEQSYQKHQISRDHGWIKLDNNFEVNFDKDPMEMRLPIRSPIK Sbjct: 3121 VKPKQKWKPFSQKQIILLEQSYQKHQISRDHGWIKLDNNFEVNFDKDPMEMRLPIRSPIK 3180 Query: 3138 RDFLSGIQIEFKQSSHQRSLRARLYWLQVDNQLPGAMFPVVFHPVAPPKSIALDSEPKPF 3197 RDFLSGIQIEFKQSSHQRSLRARLYWLQVDNQLPGAMFPVVFHPVAPPKSIALDSEPKPF Sbjct: 3181 RDFLSGIQIEFKQSSHQRSLRARLYWLQVDNQLPGAMFPVVFHPVAPPKSIALDSEPKPF 3240 Query: 3198 IDVSVITRFNEYSKVLQFKYFMVLIQEMALKIDQGFLGAIIALFTPTTDPEAERRRTKLI 3257 IDVSVITRFNEYSKVLQFKYFMVLIQEMALKIDQGFLGAIIALFTPTTDPEAERRRTKLI Sbjct: 3241 IDVSVITRFNEYSKVLQFKYFMVLIQEMALKIDQGFLGAIIALFTPTTDPEAERRRTKLI 3300 Query: 3258 QQDIDALNAELMETSMTDMSILSFFEHFHISPVKLHLSLSLGSGGEESDKEKQEMFAVHS 3317 QQDIDALNAELMETSMTDMSILSFFEHFHISPVKLHLSLSLGSGGEESDKEKQEMFAVHS Sbjct: 3301 QQDIDALNAELMETSMTDMSILSFFEHFHISPVKLHLSLSLGSGGEESDKEKQEMFAVHS 3360 Query: 3318 VNLLLKSIGATLTDVDDLIFKLAYYEIRYQFYKRDQLIWSVVRHYSEQFLKQMYVLVLGL 3377 VNLLLKSIGATLTDVDDLIFKLAYYEIRYQFYKRDQLIWSVVRHYSEQFLKQMYVLVLGL Sbjct: 3361 VNLLLKSIGATLTDVDDLIFKLAYYEIRYQFYKRDQLIWSVVRHYSEQFLKQMYVLVLGL 3420 Query: 3378 DVLGNPFGLIRGLSEGVEALFYEPFQGAVQGPEEFAEGLVIGVRSLFGHTVGGAAGVVSR 3437 DVLGNPFGLIRGLSEGVEALFYEPFQGAVQGPEEFAEGLVIGVRSLFGHTVGGAAGVVSR Sbjct: 3421 DVLGNPFGLIRGLSEGVEALFYEPFQGAVQGPEEFAEGLVIGVRSLFGHTVGGAAGVVSR 3480 Query: 3438 ITGSVGKGLAAITMDKEYQQKRREELSRQPRDFGDSLARGGKGFLRGVVGGVTGIITKPV 3497 ITGSVGKGLAAITMDKEYQQKRREELSRQPRDFGDSLARGGKGFLRGVVGGVTGIITKPV Sbjct: 3481 ITGSVGKGLAAITMDKEYQQKRREELSRQPRDFGDSLARGGKGFLRGVVGGVTGIITKPV 3540 Query: 3498 EGAKKEGAAGFFKGIGKGLVGAVARPTGGIVDMASSTFQGIQRAAESTEEVSSLRPPRLI 3557 EGAKKEGAAGFFKGIGKGLVGAVARPTGGIVDMASSTFQGIQRAAESTEEVSSLRPPRLI Sbjct: 3541 EGAKKEGAAGFFKGIGKGLVGAVARPTGGIVDMASSTFQGIQRAAESTEEVSSLRPPRLI 3600 Query: 3558 HEDGIIRPYDRQESEGSDLLEQELEIQE 3585 HEDGIIRPYDRQESEGSDLLEQELEIQE Sbjct: 3601 HEDGIIRPYDRQESEGSDLLEQELEIQE 3628 >gi|66347828 vacuolar protein sorting 13C protein isoform 2A [Homo sapiens] Length = 3753 Score = 6995 bits (18150), Expect = 0.0 Identities = 3578/3625 (98%), Positives = 3580/3625 (98%), Gaps = 43/3625 (1%) Query: 1 MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAG 60 MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAG Sbjct: 1 MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAG 60 Query: 61 QIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEE 120 QIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEE Sbjct: 61 QIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEE 120 Query: 121 ALQKAAEK-------------------------------------------DKPKEAKKD 137 ALQKAAEK DKPKEAKKD Sbjct: 121 ALQKAAEKGTHSGEFIYGLENFVYKDIKPGRKRKKHKKHFKKPFKGLDRSKDKPKEAKKD 180 Query: 138 TFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLGELSLLTANEHWTPCILN 197 TFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLGELSLLTANEHWTPCILN Sbjct: 181 TFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLGELSLLTANEHWTPCILN 240 Query: 198 EADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILDQLKNEILTSGNIPPNYQYIFQPIS 257 EADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILDQLKNEILTSGNIPPNYQYIFQPIS Sbjct: 241 EADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILDQLKNEILTSGNIPPNYQYIFQPIS 300 Query: 258 ASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKPQYLSMIDLLESVDYMVRNAPYRKY 317 ASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKPQYLSMIDLLESVDYMVRNAPYRKY Sbjct: 301 ASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKPQYLSMIDLLESVDYMVRNAPYRKY 360 Query: 318 KPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIKKHRQLLKSYKIAYKNKLTQSK 377 KPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIKKHRQLLKSYKIAYKNKLTQSK Sbjct: 361 KPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIKKHRQLLKSYKIAYKNKLTQSK 420 Query: 378 VSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKSADTGEKRGGWFSGLWGK 437 VSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKSADTGEKRGGWFSGLWGK Sbjct: 421 VSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKSADTGEKRGGWFSGLWGK 480 Query: 438 KESKKKDEESLIPETIDDLMTPEEKDKLFTAIGYSESTHNLTLPKQYVAHIMTLKLVSTS 497 KESKKKDEESLIPETIDDLMTPEEKDKLFTAIGYSESTHNLTLPKQYVAHIMTLKLVSTS Sbjct: 481 KESKKKDEESLIPETIDDLMTPEEKDKLFTAIGYSESTHNLTLPKQYVAHIMTLKLVSTS 540 Query: 498 VTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVEAKLEHWYITGLRQQDIVPSLVASI 557 VTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVEAKLEHWYITGLRQQDIVPSLVASI Sbjct: 541 VTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVEAKLEHWYITGLRQQDIVPSLVASI 600 Query: 558 GDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIYDAKTVNAVVEFFQSNKGLDLEQIT 617 GDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIYDAKTVNAVVEFFQSNKGLDLEQIT Sbjct: 601 GDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIYDAKTVNAVVEFFQSNKGLDLEQIT 660 Query: 618 SATLMKLEEIKERTATGLTHIIETRKVLDLRINLKPSYLVVPQTGFHHEKSDLLILDFGT 677 SATLMKLEEIKERTATGLTHIIETRKVLDLRINLKPSYLVVPQTGFHHEKSDLLILDFGT Sbjct: 661 SATLMKLEEIKERTATGLTHIIETRKVLDLRINLKPSYLVVPQTGFHHEKSDLLILDFGT 720 Query: 678 FQLNSKDQGLQKTTNSSLEEIMDKAYDKFDVEIKNVQLLFARAEETWKKCRFQHPSTMHI 737 FQLNSKDQGLQKTTNSSLEEIMDKAYDKFDVEIKNVQLLFARAEETWKKCRFQHPSTMHI Sbjct: 721 FQLNSKDQGLQKTTNSSLEEIMDKAYDKFDVEIKNVQLLFARAEETWKKCRFQHPSTMHI 780 Query: 738 LQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVRISDQKMKDVLYLMNSIPLPQKSSA 797 LQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVRISDQKMKDVLYLMNSIPLPQKSSA Sbjct: 781 LQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVRISDQKMKDVLYLMNSIPLPQKSSA 840 Query: 798 QSPERQVSSIPIISGGTKGLLGTSLLLDTVESESDDEYFDAEDGEPQTCKSMKGSELKKA 857 QSPERQVSSIPIISGGTKGLLGTSLLLDTVESESDDEYFDAEDGEPQTCKSMKGSELKKA Sbjct: 841 QSPERQVSSIPIISGGTKGLLGTSLLLDTVESESDDEYFDAEDGEPQTCKSMKGSELKKA 900 Query: 858 AEVPNEELINLLLKFEIKEVILEFTKQQKEEDTILVFNVTQLGTEATMRTFDLTVVSYLK 917 AEVPNEELINLLLKFEIKEVILEFTKQQKEEDTILVFNVTQLGTEATMRTFDLTVVSYLK Sbjct: 901 AEVPNEELINLLLKFEIKEVILEFTKQQKEEDTILVFNVTQLGTEATMRTFDLTVVSYLK 960 Query: 918 KISLDYHEIEGSKRKPLHLISSSDKPGLDLLKVEYIKADKNGPSFQTAFGKTEQTVKVAF 977 KISLDYHEIEGSKRKPLHLISSSDKPGLDLLKVEYIKADKNGPSFQTAFGKTEQTVKVAF Sbjct: 961 KISLDYHEIEGSKRKPLHLISSSDKPGLDLLKVEYIKADKNGPSFQTAFGKTEQTVKVAF 1020 Query: 978 SSLNLLLQTQALVASINYLTTIIPSDDQSISVAKEVQISTEKQQKNSTLPKAIVSSRDSD 1037 SSLNLLLQTQALVASINYLTTIIPSDDQSISVAKEVQISTEKQQKNSTLPKAIVSSRDSD Sbjct: 1021 SSLNLLLQTQALVASINYLTTIIPSDDQSISVAKEVQISTEKQQKNSTLPKAIVSSRDSD 1080 Query: 1038 IIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSSLSLQSRKQSLFARLENIIVTDVDPK 1097 IIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSSLSLQSRKQSLFARLENIIVTDVDPK Sbjct: 1081 IIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSSLSLQSRKQSLFARLENIIVTDVDPK 1140 Query: 1098 TVHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMSKVDGVLSLNVGCIQIVYLHKFLMSL 1157 TVHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMSKVDGVLSLNVGCIQIVYLHKFLMSL Sbjct: 1141 TVHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMSKVDGVLSLNVGCIQIVYLHKFLMSL 1200 Query: 1158 LNFLNNFQTAKESLSAATAQAAERAATSVKDLAQRSFRVSINIDLKAPVIVIPQSSISTN 1217 LNFLNNFQTAKESLSAATAQAAERAATSVKDLAQRSFRVSINIDLKAPVIVIPQSSISTN Sbjct: 1201 LNFLNNFQTAKESLSAATAQAAERAATSVKDLAQRSFRVSINIDLKAPVIVIPQSSISTN 1260 Query: 1218 AVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQLTKLTLYRTVIQPGIYHPDIQLLHP 1277 AVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQLTKLTLYRTVIQPGIYHPDIQLLHP Sbjct: 1261 AVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQLTKLTLYRTVIQPGIYHPDIQLLHP 1320 Query: 1278 INLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLNQEDLNLLFRILTENLCEGTEDLDK 1337 INLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLNQEDLNLLFRILTENLCEGTEDLDK Sbjct: 1321 INLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLNQEDLNLLFRILTENLCEGTEDLDK 1380 Query: 1338 VKPRVQETGEIKEPLEISISQDVHDSKNTLTTGVEEIRSVDIINMLLNFEIKEVVVTLMK 1397 VKPRVQETGEIKEPLEISISQDVHDSKNTLTTGVEEIRSVDIINMLLNFEIKEVVVTLMK Sbjct: 1381 VKPRVQETGEIKEPLEISISQDVHDSKNTLTTGVEEIRSVDIINMLLNFEIKEVVVTLMK 1440 Query: 1398 KSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFDFTDSKGEPLHIINSSNV 1457 KSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFDFTDSKGEPLHIINSSNV Sbjct: 1441 KSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFDFTDSKGEPLHIINSSNV 1500 Query: 1458 TDEPLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLHLEALLSFMDFLSSAAPF 1517 TDEPLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLHLEALLSFMDFLSSAAPF Sbjct: 1501 TDEPLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLHLEALLSFMDFLSSAAPF 1560 Query: 1518 SEPSSSEKESELKPLVGESRSIAVKAVSSNISQKDVFDLKITAELNAFNVFVCDQKCNIA 1577 SEPSSSEKESELKPLVGESRSIAVKAVSSNISQKDVFDLKITAELNAFNVFVCDQKCNIA Sbjct: 1561 SEPSSSEKESELKPLVGESRSIAVKAVSSNISQKDVFDLKITAELNAFNVFVCDQKCNIA 1620 Query: 1578 DIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQSIHKKAVSILGDEVFRFQLTLYPDA 1637 DIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQSIHKKAVSILGDEVFRFQLTLYPDA Sbjct: 1621 DIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQSIHKKAVSILGDEVFRFQLTLYPDA 1680 Query: 1638 TEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQTAKEALSTATVQAAERA 1697 TEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQTAKEALSTATVQAAERA Sbjct: 1681 TEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQTAKEALSTATVQAAERA 1740 Query: 1698 ASSMKDLAQKSFRLLMDINLKAPVIIIPQSSVSPNAVIADLGLIRVENKFSLVPMEHYSL 1757 ASSMKDLAQKSFRLLMDINLKAPVIIIPQSSVSPNAVIADLGLIRVENKFSLVPMEHYSL Sbjct: 1741 ASSMKDLAQKSFRLLMDINLKAPVIIIPQSSVSPNAVIADLGLIRVENKFSLVPMEHYSL 1800 Query: 1758 PPVIDKMNIELTQLKLSRTILQASLPQNDIEILKPVNMLLSIQRNLAAAWYVQIPGMEIK 1817 PPVIDKMNIELTQLKLSRTILQASLPQNDIEILKPVNMLLSIQRNLAAAWYVQIPGMEIK Sbjct: 1801 PPVIDKMNIELTQLKLSRTILQASLPQNDIEILKPVNMLLSIQRNLAAAWYVQIPGMEIK 1860 Query: 1818 GKLKPMQVALSEDDLTVLMKILLENLGEASSQPSPTQSVQETVRVRKVDVSSVPDHLKEQ 1877 GKLKPMQVALSEDDLTVLMKILLENLGEASSQPSPTQSVQETVRVRKVDVSSVPDHLKEQ Sbjct: 1861 GKLKPMQVALSEDDLTVLMKILLENLGEASSQPSPTQSVQETVRVRKVDVSSVPDHLKEQ 1920 Query: 1878 EDWTDSKLSMNQIVSLQFDFHFESLSIILYNNDINQESGVAFHNDSFQLGELRLHLMASS 1937 EDWTDSKLSMNQIVSLQFDFHFESLSIILYNNDINQESGVAFHNDSFQLGELRLHLMASS Sbjct: 1921 EDWTDSKLSMNQIVSLQFDFHFESLSIILYNNDINQESGVAFHNDSFQLGELRLHLMASS 1980 Query: 1938 GKMFKDGSMNVSVKLKTCTLDDLREGIERATSRMIDRKNDQDNNSSMIDISYKQDKNGSQ 1997 GKMFKDGSMNVSVKLKTCTLDDLREGIERATSRMIDRKNDQDNNSSMIDISYKQDKNGSQ Sbjct: 1981 GKMFKDGSMNVSVKLKTCTLDDLREGIERATSRMIDRKNDQDNNSSMIDISYKQDKNGSQ 2040 Query: 1998 IDAVLDKLYVCASVEFLMTVADFFIKAVPQSPENVAKETQILPRQTATGKVKIEKDDSVR 2057 IDAVLDKLYVCASVEFLMTVADFFIKAVPQSPENVAKETQILPRQTATGKVKIEKDDSVR Sbjct: 2041 IDAVLDKLYVCASVEFLMTVADFFIKAVPQSPENVAKETQILPRQTATGKVKIEKDDSVR 2100 Query: 2058 PNMTLKAMITDPEVVFVASLTKADAPALTASFQCNLSLSTSKLEQMMEASVRDLKVLACP 2117 PNMTLKAMITDPEVVFVASLTKADAPALTASFQCNLSLSTSKLEQMMEASVRDLKVLACP Sbjct: 2101 PNMTLKAMITDPEVVFVASLTKADAPALTASFQCNLSLSTSKLEQMMEASVRDLKVLACP 2160 Query: 2118 FLREKRGKNITTVLQPCSLFMEKCTWASGKQNINIMVKEFIIKISPIILNTVLTIMAALS 2177 FLREKRGKNITTVLQPCSLFMEKCTWASGKQNINIMVKEFIIKISPIILNTVLTIMAALS Sbjct: 2161 FLREKRGKNITTVLQPCSLFMEKCTWASGKQNINIMVKEFIIKISPIILNTVLTIMAALS 2220 Query: 2178 PKTKEDGSKDTSKEMENLWGIKSINDYNTWFLGVDTATEITESFKGIEHSLIEENCGVVV 2237 PKTKEDGSKDTSKEMENLWGIKSINDYNTWFLGVDTATEITESFKGIEHSLIEENCGVVV Sbjct: 2221 PKTKEDGSKDTSKEMENLWGIKSINDYNTWFLGVDTATEITESFKGIEHSLIEENCGVVV 2280 Query: 2238 ESIQVTLECGLGHRTVPLLLAESKFSGNIKNWTSLMAAVADVTLQVHYYNEIHAVWEPLI 2297 ESIQVTLECGLGHRTVPLLLAESKFSGNIKNWTSLMAAVADVTLQVHYYNEIHAVWEPLI Sbjct: 2281 ESIQVTLECGLGHRTVPLLLAESKFSGNIKNWTSLMAAVADVTLQVHYYNEIHAVWEPLI 2340 Query: 2298 ERVEGKRQWNLRLDVKKNPVQDKSLLPGDDFIPEPQMAIHISSGNTMNITISKSCLNVFN 2357 ERVEGKRQWNLRLDVKKNPVQDKSLLPGDDFIPEPQMAIHISSGNTMNITISKSCLNVFN Sbjct: 2341 ERVEGKRQWNLRLDVKKNPVQDKSLLPGDDFIPEPQMAIHISSGNTMNITISKSCLNVFN 2400 Query: 2358 NLAKGFSEGTASTFDYSLKDRAPFTVKNAVGVPIKVKPNCNLRVMGFPEKSDIFDVDAGQ 2417 NLAKGFSEGTASTFDYSLKDRAPFTVKNAVGVPIKVKPNCNLRVMGFPEKSDIFDVDAGQ Sbjct: 2401 NLAKGFSEGTASTFDYSLKDRAPFTVKNAVGVPIKVKPNCNLRVMGFPEKSDIFDVDAGQ 2460 Query: 2418 NLELEYASMVPSSQGNLSILSRQESSFFTLTIVPHGYTEVANIPVARPGRRLYNVRNPNA 2477 NLELEYASMVPSSQGNLSILSRQESSFFTLTIVPHGYTEVANIPVARPGRRLYNVRNPNA Sbjct: 2461 NLELEYASMVPSSQGNLSILSRQESSFFTLTIVPHGYTEVANIPVARPGRRLYNVRNPNA 2520 Query: 2478 SHSDSVLVQIDATEGNKVITLRSPLQIKNHFSIAFIIYKFVKNVKLLERIGIARPEEEFH 2537 SHSDSVLVQIDATEGNKVITLRSPLQIKNHFSIAFIIYKFVKNVKLLERIGIARPEEEFH Sbjct: 2521 SHSDSVLVQIDATEGNKVITLRSPLQIKNHFSIAFIIYKFVKNVKLLERIGIARPEEEFH 2580 Query: 2538 VPLDSYRCQLFIQPAGILEHQYKESTTYISWKEELHRSREVRCMLQCPSVEVSFLPLIVN 2597 VPLDSYRCQLFIQPAGILEHQYKESTTYISWKEELHRSREVRCMLQCPSVEVSFLPLIVN Sbjct: 2581 VPLDSYRCQLFIQPAGILEHQYKESTTYISWKEELHRSREVRCMLQCPSVEVSFLPLIVN 2640 Query: 2598 TVALPDELSYICTHGEDWDVAYIIHLYPSLTLRNLLPYSLRYLLEGTAETHELAEGSTAD 2657 TVALPDELSYICTHGEDWDVAYIIHLYPSLTLRNLLPYSLRYLLEGTAETHELAEGSTAD Sbjct: 2641 TVALPDELSYICTHGEDWDVAYIIHLYPSLTLRNLLPYSLRYLLEGTAETHELAEGSTAD 2700 Query: 2658 VLHSRISGEIMELVLVKYQGKNWNGHFRIRDTLPEFFPVCFSSDSTEVTTVDLSVHVRRI 2717 VLHSRISGEIMELVLVKYQGKNWNGHFRIRDTLPEFFPVCFSSDSTEVTTVDLSVHVRRI Sbjct: 2701 VLHSRISGEIMELVLVKYQGKNWNGHFRIRDTLPEFFPVCFSSDSTEVTTVDLSVHVRRI 2760 Query: 2718 GSRMVLSVFSPYWLINKTTRVLQYRSEDIHVKHPADFRDIILFSFKKKNIFTKNKVQLKI 2777 GSRMVLSVFSPYWLINKTTRVLQYRSEDIHVKHPADFRDIILFSFKKKNIFTKNKVQLKI Sbjct: 2761 GSRMVLSVFSPYWLINKTTRVLQYRSEDIHVKHPADFRDIILFSFKKKNIFTKNKVQLKI 2820 Query: 2778 STSAWSSSFSLDTVGSYGCVKCPANNMEYLVGVSIKMSSFNLSRIVTLTPFCTIANKSSL 2837 STSAWSSSFSLDTVGSYGCVKCPANNMEYLVGVSIKMSSFNLSRIVTLTPFCTIANKSSL Sbjct: 2821 STSAWSSSFSLDTVGSYGCVKCPANNMEYLVGVSIKMSSFNLSRIVTLTPFCTIANKSSL 2880 Query: 2838 ELEVGEIASDGSMPTNKWNYIASSECLPFWPESLSGKLCVRVVGCEGSSKPFFYNRQDNG 2897 ELEVGEIASDGSMPTNKWNYIASSECLPFWPESLSGKLCVRVVGCEGSSKPFFYNRQDNG Sbjct: 2881 ELEVGEIASDGSMPTNKWNYIASSECLPFWPESLSGKLCVRVVGCEGSSKPFFYNRQDNG 2940 Query: 2898 TLLSLEDLNGGILVDVNTAEHSTVITFSDYHEGSAPALIMNHTPWDILTYKQSGSPEEMV 2957 TLLSLEDLNGGILVDVNTAEHSTVITFSDYHEGSAPALIMNHTPWDILTYKQSGSPEEMV Sbjct: 2941 TLLSLEDLNGGILVDVNTAEHSTVITFSDYHEGSAPALIMNHTPWDILTYKQSGSPEEMV 3000 Query: 2958 LLPRQARLFAWADPTGTRKLTWTYAANVGEHDLLKDGCGQFPYDANIQIHWVSFLDGRQR 3017 LLPRQARLFAWADPTGTRKLTWTYAANVGEHDLLKDGCGQFPYDANIQIHWVSFLDGRQR Sbjct: 3001 LLPRQARLFAWADPTGTRKLTWTYAANVGEHDLLKDGCGQFPYDANIQIHWVSFLDGRQR 3060 Query: 3018 VLLFTDDVALVSKALQAEEMEQADYEITLSLHSLGLSLVNNESKQEVSYIGITSSGVVWE 3077 VLLFTDDVALVSKALQAEEMEQADYEITLSLHSLGLSLVNNESKQEVSYIGITSSGVVWE Sbjct: 3061 VLLFTDDVALVSKALQAEEMEQADYEITLSLHSLGLSLVNNESKQEVSYIGITSSGVVWE 3120 Query: 3078 VKPKQKWKPFSQKQIILLEQSYQKHQISRDHGWIKLDNNFEVNFDKDPMEMRLPIRSPIK 3137 VKPKQKWKPFSQKQIILLEQSYQKHQISRDHGWIKLDNNFEVNFDKDPMEMRLPIRSPIK Sbjct: 3121 VKPKQKWKPFSQKQIILLEQSYQKHQISRDHGWIKLDNNFEVNFDKDPMEMRLPIRSPIK 3180 Query: 3138 RDFLSGIQIEFKQSSHQRSLRARLYWLQVDNQLPGAMFPVVFHPVAPPKSIALDSEPKPF 3197 RDFLSGIQIEFKQSSHQRSLRARLYWLQVDNQLPGAMFPVVFHPVAPPKSIALDSEPKPF Sbjct: 3181 RDFLSGIQIEFKQSSHQRSLRARLYWLQVDNQLPGAMFPVVFHPVAPPKSIALDSEPKPF 3240 Query: 3198 IDVSVITRFNEYSKVLQFKYFMVLIQEMALKIDQGFLGAIIALFTPTTDPEAERRRTKLI 3257 IDVSVITRFNEYSKVLQFKYFMVLIQEMALKIDQGFLGAIIALFTPTTDPEAERRRTKLI Sbjct: 3241 IDVSVITRFNEYSKVLQFKYFMVLIQEMALKIDQGFLGAIIALFTPTTDPEAERRRTKLI 3300 Query: 3258 QQDIDALNAELMETSMTDMSILSFFEHFHISPVKLHLSLSLGSGGEESDKEKQEMFAVHS 3317 QQDIDALNAELMETSMTDMSILSFFEHFHISPVKLHLSLSLGSGGEESDKEKQEMFAVHS Sbjct: 3301 QQDIDALNAELMETSMTDMSILSFFEHFHISPVKLHLSLSLGSGGEESDKEKQEMFAVHS 3360 Query: 3318 VNLLLKSIGATLTDVDDLIFKLAYYEIRYQFYKRDQLIWSVVRHYSEQFLKQMYVLVLGL 3377 VNLLLKSIGATLTDVDDLIFKLAYYEIRYQFYKRDQLIWSVVRHYSEQFLKQMYVLVLGL Sbjct: 3361 VNLLLKSIGATLTDVDDLIFKLAYYEIRYQFYKRDQLIWSVVRHYSEQFLKQMYVLVLGL 3420 Query: 3378 DVLGNPFGLIRGLSEGVEALFYEPFQGAVQGPEEFAEGLVIGVRSLFGHTVGGAAGVVSR 3437 DVLGNPFGLIRGLSEGVEALFYEPFQGAVQGPEEFAEGLVIGVRSLFGHTVGGAAGVVSR Sbjct: 3421 DVLGNPFGLIRGLSEGVEALFYEPFQGAVQGPEEFAEGLVIGVRSLFGHTVGGAAGVVSR 3480 Query: 3438 ITGSVGKGLAAITMDKEYQQKRREELSRQPRDFGDSLARGGKGFLRGVVGGVTGIITKPV 3497 ITGSVGKGLAAITMDKEYQQKRREELSRQPRDFGDSLARGGKGFLRGVVGGVTGIITKPV Sbjct: 3481 ITGSVGKGLAAITMDKEYQQKRREELSRQPRDFGDSLARGGKGFLRGVVGGVTGIITKPV 3540 Query: 3498 EGAKKEGAAGFFKGIGKGLVGAVARPTGGIVDMASSTFQGIQRAAESTEEVSSLRPPRLI 3557 EGAKKEGAAGFFKGIGKGLVGAVARPTGGIVDMASSTFQGIQRAAESTEEVSSLRPPRLI Sbjct: 3541 EGAKKEGAAGFFKGIGKGLVGAVARPTGGIVDMASSTFQGIQRAAESTEEVSSLRPPRLI 3600 Query: 3558 HEDGIIRPYDRQESEGSDLLEQELE 3582 HEDGIIRPYDRQESEGSDLLE ++ Sbjct: 3601 HEDGIIRPYDRQESEGSDLLENHIK 3625 >gi|15619008 vacuolar protein sorting 13A isoform B [Homo sapiens] Length = 3095 Score = 1679 bits (4348), Expect = 0.0 Identities = 982/2528 (38%), Positives = 1505/2528 (59%), Gaps = 145/2528 (5%) Query: 1145 IQIVYLHKFLMSLLNFLNNFQTAKE----SLSAATAQAAE----RAATSVKDLAQRSFRV 1196 ++I+Y + + S++ F F+ KE L+AAT E + AT + + + + Sbjct: 589 LEIIYDARTVNSIVEF---FRPPKEVHLAQLTAATLTKLEEFRSKTATGLLYIIETQKVL 645 Query: 1197 SINIDLKAPVIVIPQSSI---STNAVVVDLGLIRV----HNQFSLVSDEDYLNPPVIDR- 1248 + I+LKA I++PQ I ++N +++DLG ++V ++ V + ++DR Sbjct: 646 DLKINLKASYIIVPQDGIFSPTSNLLLLDLGHLKVTSKSRSELPDVKQGEANLKEIMDRA 705 Query: 1249 ---MDVQLTKLTL--------YRTVIQPGIYHPDIQLLHPINLE------FLVNRNLAAS 1291 D+QLT + L +R + + I + NLE F+ R Sbjct: 706 YDSFDIQLTSVQLLYSRVGDNWREARKLSVSTQHILVPMHFNLELSKAMVFMDVRMPKFK 765 Query: 1292 WYHKVPVVEIK-------GHLDSMNVSLNQEDLNLL------FRILTENLCEGTEDLDKV 1338 Y K+P++ ++ G ++ + E + + F+I T ++ K+ Sbjct: 766 IYGKLPLISLRISDKKLQGIMELIESIPKPEPVTEVSAPVKSFQIQTSTSLGTSQISQKI 825 Query: 1339 KPRVQETGEIKEPLEISISQDVHDSKNT-------LTTGVEEIR---------SVDIINM 1382 P + E+ E ++ D+ + TGV+ IR SV++ Sbjct: 826 IPLL----ELPSVSEDDSEEEFFDAPCSPLEEPLQFPTGVKSIRTRKLQKQDCSVNMTTF 881 Query: 1383 LLNFEIKEVVVTLMKKSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFDFT 1442 + FE+ +V++ + E+ VL LG E +++TYD+ A A+LK+ ++C ++ Sbjct: 882 KIRFEVPKVLIEFYHLVGDCELSVVEILVLGLGAEIEIRTYDLKANAFLKEFCLKCPEYL 941 Query: 1443 DSKGEPLHIINSSNVTDEPLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLHLE 1502 D +P++++ + + T E LL + KA+ + P+ K+ +++ Q +KV+F+SLD+ LH E Sbjct: 942 DENKKPVYLVTTLDNTMEDLLTLEYVKAEKNVPDLKSTYNNVLQLIKVNFSSLDIHLHTE 1001 Query: 1503 ALLSFMDFLSSAAPFSEPSSSEKESELKPLVGESRSIAVKAVSSNIS-QKDVFDLKITAE 1561 ALL+ +++L + P SE EK + + E + +K ++ +S +D+ L+I AE Sbjct: 1002 ALLNTINYLHNILPQSE----EKSAPVSTTETEDKGDVIKKLALKLSTNEDIITLQILAE 1057 Query: 1562 LNAFNVFVCDQKCNIADIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQSIHKKAVSI 1621 L+ +F+ DQKCNI++IKI G+D+ + ++P +T++ A+L++IIV++ D+ +I+KKAV I Sbjct: 1058 LSCLQIFIQDQKCNISEIKIEGLDSEMIMRPSETEINAKLRNIIVLDSDITAIYKKAVYI 1117 Query: 1622 LGDEVFRFQLTLYPDATEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQT 1681 G EVF F++ Y DAT G AY DM+ VD +++ VGCI++V+V KF S+L F++NFQ Sbjct: 1118 TGKEVFSFKMVSYMDATAGSAYTDMNVVDIQVNLIVGCIEVVFVTKFLYSILAFIDNFQA 1177 Query: 1682 AKEALSTATVQAAERAASSMKDLAQKSFRLLMDINLKAPVIIIPQSSVSPNAVIADLGLI 1741 AK+AL+ ATVQAA AA+ +K+LAQ+S R+ +DIN+KAPV++IPQS VS N +AD GLI Sbjct: 1178 AKQALAEATVQAAGMAATGVKELAQRSSRMALDINIKAPVVVIPQSPVSENVFVADFGLI 1237 Query: 1742 RVENKFSLVPMEHYSLPPVIDKMNIELTQLKLSRTILQASLPQNDIEILKPVNMLLSIQR 1801 + N F ++ S PPVID + I+L++++L R+ Q +++L P+N+ + ++R Sbjct: 1238 TMTNTFHMITESQSSPPPVIDLITIKLSEMRLYRSRFINDAYQEVLDLLLPLNLEVVVER 1297 Query: 1802 NLAAAWYVQIPGMEIKGKLKPMQVALSEDDLTVLMKILLENLG-EASSQPSPTQSVQETV 1860 NL WY ++P + +LKPM+ LS++D+T + K L N+ E SP + + Sbjct: 1298 NLCWEWYQEVPCFNVNAQLKPMEFILSQEDITTIFKTLHGNIWYEKDGSASPAVTKDQYS 1357 Query: 1861 RVRKVDVSSVPDHLKEQEDWTDSKLSMNQIV-----SLQFDFHFESLSIILYNNDINQES 1915 V ++ H T + + ++ +L F + L+++LY+ Q S Sbjct: 1358 ATSGV-TTNASHHSGGATVVTAAVVEVHSRALLVKTTLNISFKTDDLTMVLYSPGPKQAS 1416 Query: 1916 GVAFHNDSFQLGELRLHLMASSGKMFKDGSMNVSVKLKTCTLDDLREGIERATSRMIDRK 1975 + S +L E +L + S+ KM+ DGS S LK C LDD R +++AT RMI Sbjct: 1417 FTDVRDPSLKLAEFKLENIISTLKMYTDGSTFSSFSLKNCILDDKRPHVKKATPRMIGLT 1476 Query: 1976 NDQDNNSSMIDISYKQDKNGSQIDAVLDKLYVCASVEFLMTVADFFIKAVPQSPENVAKE 2035 D M+DI Y++ ++G DAV ++Y+CASVEFL TVA+ F++A A E Sbjct: 1477 VGFDKKD-MMDIKYRKVRDGCVTDAVFQEMYICASVEFLQTVANVFLEAYTTG---TAVE 1532 Query: 2036 TQILPRQTATGKVKIEKDDSVRPNMTLKAMITDPEVVFVASLTKADAPALTASFQCNLSL 2095 T + QT T K ++ +SV+ + +I +PE+VFVA +TK DAPAL + QC + Sbjct: 1533 TSV---QTWTAKEEVPTQESVK--WEINVIIKNPEIVFVADMTKNDAPALVITTQCEICY 1587 Query: 2096 STSKLEQMMEASVRDLKVLACPFLREKRGKNITTVLQPCSLFMEKCTWASGKQNINIMVK 2155 + M A+++DL+V ACPFL KR ITTVLQPC LF + + Q I++ VK Sbjct: 1588 KGNLENSTMTAAIKDLQVRACPFLPVKRKGKITTVLQPCDLFYQTTQKGTDPQVIDMSVK 1647 Query: 2156 EFIIKISPIILNTVLTIMAALSPKTKEDGSKDTSKEMENLWGIKSINDYNTWFLGVDTAT 2215 +K+SP+I+NT++TI +AL TKE ++T+ +LW K WFL T Sbjct: 1648 SLTLKVSPVIINTMITITSALYT-TKETIPEETASSTAHLWEKKDTKTLKMWFLEESNET 1706 Query: 2216 EITESFKGI--EHSLIEENCGVVVESIQVTLECGLGHRTVPLLLAESKFSGNIKNWTSLM 2273 E + + +I+ N ++SI + LE G+GHRTVP+LLA+S+FSG KNW+SL+ Sbjct: 1707 EKIAPTTELVPKGEMIKMN----IDSIFIVLEAGIGHRTVPMLLAKSRFSGEGKNWSSLI 1762 Query: 2274 AAVADVTLQVHYYNEIHAVWEPLIE-----RVEGKRQWNLRLDVKKNP---VQDKSLLPG 2325 + L+VHYYNE+ VWEPL+E + E R WNL + +KK + + Sbjct: 1763 NLHCQLELEVHYYNEMFGVWEPLLEPLEIDQTEDFRPWNLGIKMKKKAKMAIVESDPEEE 1822 Query: 2326 DDFIPEPQMAIHISSGNTMNITISKSCLNVFNNLAKGFSEG-TASTFDYSLKDRAPFTVK 2384 + +PE + I S + +NIT+SK L + NNL K F+E T S+ D+ +KD APF + Sbjct: 1823 NYKVPEYKTVISFHSKDQLNITLSKCGLVMLNNLVKAFTEAATGSSADF-VKDLAPFMIL 1881 Query: 2385 NAVGVPIKVKPNCNLRVMGFPEKSDIFDVDAGQNLELEYASMVPSSQGNLSILSRQESSF 2444 N++G+ I V P+ + V+ P + + G++L ++Y + N ++ S Sbjct: 1882 NSLGLTISVSPSDSFSVLNIPMAKS-YVLKNGESLSMDYIRTKDNDHFNA--MTSLSSKL 1938 Query: 2445 FTLTIVPHGYTEVANIPVARPGRRLYNVRNPNASHSDSVLVQIDATEGNKVITLRSPLQI 2504 F + + P ++ IP+ + GRRLY VR+ + S++ QID EG+K +T+RSP+QI Sbjct: 1939 FFILLTPVNHSTADKIPLTKVGRRLYTVRHRESGVERSIVCQIDTVEGSKKVTIRSPVQI 1998 Query: 2505 KNHFSIAFIIYKFVKNVKLLERIGIARPEEEFHVPLDSYRCQLFIQPAGILEHQYKESTT 2564 +NHFS+ +Y+ +G A PE EF++PL SYR +F++P +Q E Sbjct: 1999 RNHFSVPLSVYEGDT------LLGTASPENEFNIPLGSYRSFIFLKPEDE-NYQMCEGID 2051 Query: 2565 YISWKEELHRSREVRCMLQCPSVEVSFLPLIVNTVALPDELSYICTHGED-WDVAYIIHL 2623 + EE+ ++ +C S S ++N V D L+ + + ED WD+ YI+HL Sbjct: 2052 F----EEIIKNDGALLKKKCRSKNPSKESFLINIVPEKDNLTSLSVYSEDGWDLPYIMHL 2107 Query: 2624 YPSLTLRNLLPYSLRYLLEGTAET-HELAEGSTADVLHSRISGEIMELVLVKYQGKNWNG 2682 +P + LRNLLPY + Y +EG + L+EG +A + +++ + L L+ Y +W Sbjct: 2108 WPPILLRNLLPYKIAYYIEGIENSVFTLSEGHSAQICTAQLGKARLHLKLLDYLNHDWKS 2167 Query: 2683 HFRIRDTLPEFFPVCFSS-DSTEVTTVDLSVHVRRIGSRMVLSVFSPYWLINKTTRVLQY 2741 + I+ + V F+ E T +D++VH+ + V++ SPYW++NKT R+LQY Sbjct: 2168 EYHIKPNQQDISFVSFTCVTEMEKTDLDIAVHMTYNTGQTVVAFHSPYWMVNKTGRMLQY 2227 Query: 2742 RSEDIHVKHPADFRDIILFSFKKKNIFTKNKVQLKISTSAWSSSFSLDTVGSYGCVKCPA 2801 +++ IH KHP +++ +LFSF+ + F NKVQL ++ S S+ FS+DTVGS+G VKC Sbjct: 2228 KADGIHRKHPPNYKKPVLFSFQPNHFFNNNKVQLMVTDSELSNQFSIDTVGSHGAVKCKG 2287 Query: 2802 NNMEYLVGVSIKMSSFNLSRIVTLTPFCTIANKSSLELEVGEIASDGSMPTNKWNYIASS 2861 M+Y VGV+I +SSFN++RIVT TPF I NKS + V E +D KW + Sbjct: 2288 LKMDYQVGVTIDLSSFNITRIVTFTPFYMIKNKSKYHISVAEEGND------KWLSLDLE 2341 Query: 2862 ECLPFWPESLSGKLCVRVVGCEGSSKPFFYNRQDNGTLLSLEDLNGGILVDVNTAEHSTV 2921 +C+PFWPE S KL ++V E K ++N+Q+N LL L++ GGI+ +VN AEHSTV Sbjct: 2342 QCIPFWPEYASSKLLIQVERSEDPPKRIYFNKQENCILLRLDNELGGIIAEVNLAEHSTV 2401 Query: 2922 ITFSDYHEGSAPALIMNHTPWDILTYKQSGSPE-EMVLLPRQARLFAWADPTGTRKLTWT 2980 ITF DYH+G+A L++NHT +++ Y QS E E L P +A + WADP G+R+L W Sbjct: 2402 ITFLDYHDGAATFLLINHTKNELVQYNQSSLSEIEDSLPPGKAVFYTWADPVGSRRLKWR 2461 Query: 2981 YAANVGEHDLLKDGCGQFPYDANIQ-IHWVSFLDGRQRVLLFTDDVALVSKALQAEEMEQ 3039 + GE D P D + I+ VSF +G QR++LFT+D + ++E+ E Sbjct: 2462 CRKSHGEVTQKDDM--MMPIDLGEKTIYLVSFFEGLQRIILFTEDPRVFKVTYESEKAEL 2519 Query: 3040 ADYEITLSLHSLGLSLVNNESKQEVSYIGITSSGVVWEVKPKQK--WKPFSQKQIILLEQ 3097 A+ EI ++L +G+SLVNN +KQEV+YIGITSS VVWE KPK+K WKP S K LE+ Sbjct: 2520 AEQEIAVALQDVGISLVNNYTKQEVAYIGITSSDVVWETKPKKKARWKPMSVKHTEKLER 2579 Query: 3098 SYQKHQISR--DHGWIKLDNNFEVNFDKDPMEMRL--PIRSPIKRDFLSGIQIEFKQSSH 3153 ++++ S + I+LD N V M++ P ++R++L +++E+ S+H Sbjct: 2580 EFKEYTESSPSEDKVIQLDTNVPVRLTPTGHNMKILQPHVIALRRNYLPALKVEYNTSAH 2639 Query: 3154 QRSLRARLYWLQVDNQLPGAMFPVVFHPVAPPKSIALDSEPKPFIDVSVITRFNEYSKVL 3213 Q S R ++Y +Q+ NQ+ GA+FP VF+PV PPKS+ +DS PKPF DVS++ R +S++ Sbjct: 2640 QSSFRIQIYRIQIQNQIHGAVFPFVFYPVKPPKSVTMDSAPKPFTDVSIVMRSAGHSQIS 2699 Query: 3214 QFKYFMVLIQEMALKIDQGFLGAIIALFTPTTDPEAERRRTKLIQQDIDALNAELMETSM 3273 + KYF VLIQEM L++D GF+ A+ L T E +L +DI+A E S+ Sbjct: 2700 RIKYFKVLIQEMDLRLDLGFIYALTDLMTEAE--VTENTEVELFHKDIEAFKEEYKTASL 2757 Query: 3274 TDMSILSFFEHFHISPVKLHLSLSLGSGGEESDKEKQE--MFAVHSVNLLLKSIGATLTD 3331 D S +S +E+FHISP+KLHLS+SL SG EE+ KQ + VHS+NLLLKSIGATLTD Sbjct: 2758 VDQSQVSLYEYFHISPIKLHLSVSLSSGREEAKDSKQNGGLIPVHSLNLLLKSIGATLTD 2817 Query: 3332 VDDLIFKLAYYEIRYQFYKRDQLIWSVVRHYSEQFLKQMYVLVLGLDVLGNPFGLIRGLS 3391 V D++FKLA++E+ YQF+ L V+RHYS+Q +KQMYVL+LGLDVLGNPFGLIR S Sbjct: 2818 VQDVVFKLAFFELNYQFHTTSDLQSEVIRHYSKQAIKQMYVLILGLDVLGNPFGLIREFS 2877 Query: 3392 EGVEALFYEPFQGAVQGPEEFAEGLVIGVRSLFGHTVGGAAGVVSRITGSVGKGLAAITM 3451 EGVEA FYEP+QGA+QGPEEF EG+ +G+++L G VGG AG S+ITG++ KG+AA+TM Sbjct: 2878 EGVEAFFYEPYQGAIQGPEEFVEGMALGLKALVGGAVGGLAGAASKITGAMAKGVAAMTM 2937 Query: 3452 DKEYQQKRREELSRQPRDFGDSLARGGKGFLRGVVGGVTGIITKPVEGAKKEGAAGFFKG 3511 D++YQQKRRE +++QP F + + RGGKG + G V G+TGI+TKP++GA+K GAAGFFKG Sbjct: 2938 DEDYQQKRREAMNKQPAGFREGITRGGKGLVSGFVSGITGIVTKPIKGAQKGGAAGFFKG 2997 Query: 3512 IGKGLVGAVARPTGGIVDMASSTFQGIQRAAESTEEVSSLRPPRLIHEDGIIRPYDRQES 3571 +GKGLVGAVARPTGGI+DMASSTFQGI+RA E T EV SLRPPR +EDG+IRPY ++ Sbjct: 2998 VGKGLVGAVARPTGGIIDMASSTFQGIKRATE-TSEVESLRPPRFFNEDGVIRPYRLRDG 3056 Query: 3572 EGSDLLEQ 3579 G+ +L++ Sbjct: 3057 TGNQMLQK 3064 Score = 1149 bits (2971), Expect = 0.0 Identities = 616/1353 (45%), Positives = 889/1353 (65%), Gaps = 39/1353 (2%) Query: 1 MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAG 60 MV ESVV D+LNRFLGDYV +L+ SQL LGIW G VAL NLQIKENALS+LDVPFKVK G Sbjct: 1 MVFESVVVDVLNRFLGDYVVDLDTSQLSLGIWKGAVALKNLQIKENALSQLDVPFKVKVG 60 Query: 61 QIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEE 120 I L L IPWKNLY + V A LE +YLL+VP + IKYD +KEEK L + KQ+EL RIEE Sbjct: 61 HIGNLKLIIPWKNLYTQPVEAVLEEIYLLIVPSSRIKYDPLKEEKQLMEAKQQELKRIEE 120 Query: 121 ALQKAAEKDKPKEAKKDTFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLG 180 A QK ++++ K+DTF EKL TQ+IKN+QVKI+ IHI+YEDD+T+ +PLSFG++L Sbjct: 121 AKQKVVDQEQHLPEKQDTFAEKLVTQIIKNLQVKISSIHIRYEDDITNRDKPLSFGISLQ 180 Query: 181 ELSLLTANEHWTPCILNEADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILDQLKNEIL 240 LS+ T +++W PC+ +E +K++ KLIRLD+L AYWNV M Y + LD LKN I+ Sbjct: 181 NLSMQTTDQYWVPCLHDETEKLVRKLIRLDNLFAYWNVKSQMFYLSDYDNSLDDLKNGIV 240 Query: 241 TSGNIPPNYQYIFQPISASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKPQYLSMID 300 +P Y ++F+PISA+AKL MN ++ + PK++ IE+ NIAIE KPQY S+++ Sbjct: 241 NENIVPEGYDFVFRPISANAKLVMNRRSDFDFSAPKINLEIELHNIAIEFNKPQYFSIME 300 Query: 301 LLESVDYMVRNAPYRKYKPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIKKHRQ 360 LLESVD M +N PYRK+KP +PLH + R WW YAI VLEV++ MWSW +I+KHRQ Sbjct: 301 LLESVDMMAQNLPYRKFKPDVPLHHHAREWWAYAIHGVLEVNVCPRLWMWSWKHIRKHRQ 360 Query: 361 LLKSYKIAYKNKLTQSKVSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKS 420 +K YK YK KLT K E+ +++LEKTLDVFNI +ARQ A+VEV ++G K+ K+ Sbjct: 361 KVKQYKELYKKKLTSKKPPGELLVSLEELEKTLDVFNITIARQTAEVEVKKAGYKIYKEG 420 Query: 421 ADTGEKRGGWFSGLWGKKESKKKDEE-SLIPETIDDLMTPEEKDKLFTAIGYSESTHNLT 479 E GWFS LW E +++ + PET+++++TPEEK L+ AIGYSE+ + T Sbjct: 421 VKDPEDNKGWFSWLWSWSEQNTNEQQPDVQPETLEEMLTPEEKALLYEAIGYSETAVDPT 480 Query: 480 LPKQYVAHIMTLKLVSTSVTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVEAKLEHW 539 L K + A + L S S+ +REN PE++ I I T + QRPGAQA+K E K++ + Sbjct: 481 LLKTFEALKFFVHLKSMSIVLRENHQKPELVDIVIEEFSTLIVQRPGAQAIKFETKIDSF 540 Query: 540 YITGLRQQDIVPSLVASIGDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIYDAKTVN 599 +ITGL P L++S+ D SL +I FE NP D Q I++++P+E+IYDA+TVN Sbjct: 541 HITGLPDNSEKPRLLSSL-DDAMSLFQITFEINPLDETVSQRCIIEAEPLEIIYDARTVN 599 Query: 600 AVVEFFQSNKGLDLEQITSATLMKLEEIKERTATGLTHIIETRKVLDLRINLKPSYLVVP 659 ++VEFF+ K + L Q+T+ATL KLEE + +TATGL +IIET+KVLDL+INLK SY++VP Sbjct: 600 SIVEFFRPPKEVHLAQLTAATLTKLEEFRSKTATGLLYIIETQKVLDLKINLKASYIIVP 659 Query: 660 QTGFHHEKSDLLILDFGTFQLNSKDQGL---QKTTNSSLEEIMDKAYDKFDVEIKNVQLL 716 Q G S+LL+LD G ++ SK + K ++L+EIMD+AYD FD+++ +VQLL Sbjct: 660 QDGIFSPTSNLLLLDLGHLKVTSKSRSELPDVKQGEANLKEIMDRAYDSFDIQLTSVQLL 719 Query: 717 FARAEETWKKCRFQHPSTMHILQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVRISD 776 ++R + W++ R ST HIL PM ++EL+KAMV D+RM +FK+ G LPL+ +RISD Sbjct: 720 YSRVGDNWREARKLSVSTQHILVPMHFNLELSKAMVFMDVRMPKFKIYGKLPLISLRISD 779 Query: 777 QKMKDVLYLMNSIPLPQKSSAQSPERQVSS-IPIISGGTKGLLGTSLLLDTV-------- 827 +K++ ++ L+ SIP P+ P +VS+ + T LGTS + + Sbjct: 780 KKLQGIMELIESIPKPE------PVTEVSAPVKSFQIQTSTSLGTSQISQKIIPLLELPS 833 Query: 828 --ESESDDEYFDAEDGE-------PQTCKSMKGSELKKAAEVPNEELINLLLKFEIKEVI 878 E +S++E+FDA P KS++ +L+K + + + ++FE+ +V+ Sbjct: 834 VSEDDSEEEFFDAPCSPLEEPLQFPTGVKSIRTRKLQK--QDCSVNMTTFKIRFEVPKVL 891 Query: 879 LEFTKQQKE-EDTILVFNVTQLGTEATMRTFDLTVVSYLKKISLDYHEIEGSKRKPLHLI 937 +EF + E +++ V LG E +RT+DL ++LK+ L E +KP++L+ Sbjct: 892 IEFYHLVGDCELSVVEILVLGLGAEIEIRTYDLKANAFLKEFCLKCPEYLDENKKPVYLV 951 Query: 938 SSSDKPGLDLLKVEYIKADKNGPSFQTAFGKTEQTVKVAFSSLNLLLQTQALVASINYLT 997 ++ D DLL +EY+KA+KN P ++ + Q +KV FSSL++ L T+AL+ +INYL Sbjct: 952 TTLDNTMEDLLTLEYVKAEKNVPDLKSTYNNVLQLIKVNFSSLDIHLHTEALLNTINYLH 1011 Query: 998 TIIP-SDDQSISVAKEVQISTEKQQKNSTLPK-AIVSSRDSDIIDFRLFAKLNAFCVIVC 1055 I+P S+++S V+ +TE + K + K A+ S + DII ++ A+L+ + + Sbjct: 1012 NILPQSEEKSAPVS-----TTETEDKGDVIKKLALKLSTNEDIITLQILAELSCLQIFIQ 1066 Query: 1056 NEKNNIAEIKIQGLDSSLSLQSRKQSLFARLENIIVTDVDPKTVHKKAVSIMGNEVFRFN 1115 ++K NI+EIKI+GLDS + ++ + + A+L NIIV D D ++KKAV I G EVF F Sbjct: 1067 DQKCNISEIKIEGLDSEMIMRPSETEINAKLRNIIVLDSDITAIYKKAVYITGKEVFSFK 1126 Query: 1116 LDLYPDATEGDLYTDMSKVDGVLSLNVGCIQIVYLHKFLMSLLNFLNNFQTAKESLSAAT 1175 + Y DAT G YTDM+ VD ++L VGCI++V++ KFL S+L F++NFQ AK++L+ AT Sbjct: 1127 MVSYMDATAGSAYTDMNVVDIQVNLIVGCIEVVFVTKFLYSILAFIDNFQAAKQALAEAT 1186 Query: 1176 AQAAERAATSVKDLAQRSFRVSINIDLKAPVIVIPQSSISTNAVVVDLGLIRVHNQFSLV 1235 QAA AAT VK+LAQRS R++++I++KAPV+VIPQS +S N V D GLI + N F ++ Sbjct: 1187 VQAAGMAATGVKELAQRSSRMALDINIKAPVVVIPQSPVSENVFVADFGLITMTNTFHMI 1246 Query: 1236 SDEDYLNPPVIDRMDVQLTKLTLYRTVIQPGIYHPDIQLLHPINLEFLVNRNLAASWYHK 1295 ++ PPVID + ++L+++ LYR+ Y + LL P+NLE +V RNL WY + Sbjct: 1247 TESQSSPPPVIDLITIKLSEMRLYRSRFINDAYQEVLDLLLPLNLEVVVERNLCWEWYQE 1306 Query: 1296 VPVVEIKGHLDSMNVSLNQEDLNLLFRILTENL 1328 VP + L M L+QED+ +F+ L N+ Sbjct: 1307 VPCFNVNAQLKPMEFILSQEDITTIFKTLHGNI 1339 Score = 54.7 bits (130), Expect = 2e-06 Identities = 82/394 (20%), Positives = 175/394 (44%), Gaps = 57/394 (14%) Query: 1517 FSEPSSSEKESELKP------LVGESRSIAVKAVSSNISQKD-----VFD-LKITAELNA 1564 +SE +++E++ +++P L E +++ +A+ + + D F+ LK L + Sbjct: 437 WSEQNTNEQQPDVQPETLEEMLTPEEKALLYEAIGYSETAVDPTLLKTFEALKFFVHLKS 496 Query: 1565 FNVFVCD--QKCNIADIKIHGMDASISVKPKQTDVF--ARLKDIIVMNVDLQSIHKKAVS 1620 ++ + + QK + DI I I +P + ++ + + S + +S Sbjct: 497 MSIVLRENHQKPELVDIVIEEFSTLIVQRPGAQAIKFETKIDSFHITGLPDNSEKPRLLS 556 Query: 1621 ILGDEVFRFQLTLYPDATEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQ 1680 L D + FQ+T + + V + + ++I+Y + S++ F F+ Sbjct: 557 SLDDAMSLFQITFEINPLD-------ETVSQRCIIEAEPLEIIYDARTVNSIVEF---FR 606 Query: 1681 TAKEA----LSTATVQAAE----RAASSMKDLAQKSFRLLMDINLKAPVIIIPQSSV--- 1729 KE L+ AT+ E + A+ + + + L + INLKA II+PQ + Sbjct: 607 PPKEVHLAQLTAATLTKLEEFRSKTATGLLYIIETQKVLDLKINLKASYIIVPQDGIFSP 666 Query: 1730 SPNAVIADLGLIRVENK----FSLVPMEHYSLPPVIDK----MNIELTQLKLSRTIL--- 1778 + N ++ DLG ++V +K V +L ++D+ +I+LT ++L + + Sbjct: 667 TSNLLLLDLGHLKVTSKSRSELPDVKQGEANLKEIMDRAYDSFDIQLTSVQLLYSRVGDN 726 Query: 1779 ---QASLPQNDIEILKPVNMLLSIQRNLAAAWYVQIPGMEIKGKLKPMQVALSEDDLTVL 1835 L + IL P++ L + + + V++P +I GKL + + +S+ L + Sbjct: 727 WREARKLSVSTQHILVPMHFNLELSKAM-VFMDVRMPKFKIYGKLPLISLRISDKKLQGI 785 Query: 1836 MKILLENLGEASSQPSPTQSVQETVRVRKVDVSS 1869 M+++ E+ +P P V V+ ++ S+ Sbjct: 786 MELI-----ESIPKPEPVTEVSAPVKSFQIQTST 814 >gi|66346676 vacuolar protein sorting 13A isoform D [Homo sapiens] Length = 3069 Score = 1679 bits (4347), Expect = 0.0 Identities = 982/2527 (38%), Positives = 1504/2527 (59%), Gaps = 145/2527 (5%) Query: 1145 IQIVYLHKFLMSLLNFLNNFQTAKE----SLSAATAQAAE----RAATSVKDLAQRSFRV 1196 ++I+Y + + S++ F F+ KE L+AAT E + AT + + + + Sbjct: 589 LEIIYDARTVNSIVEF---FRPPKEVHLAQLTAATLTKLEEFRSKTATGLLYIIETQKVL 645 Query: 1197 SINIDLKAPVIVIPQSSI---STNAVVVDLGLIRV----HNQFSLVSDEDYLNPPVIDR- 1248 + I+LKA I++PQ I ++N +++DLG ++V ++ V + ++DR Sbjct: 646 DLKINLKASYIIVPQDGIFSPTSNLLLLDLGHLKVTSKSRSELPDVKQGEANLKEIMDRA 705 Query: 1249 ---MDVQLTKLTL--------YRTVIQPGIYHPDIQLLHPINLE------FLVNRNLAAS 1291 D+QLT + L +R + + I + NLE F+ R Sbjct: 706 YDSFDIQLTSVQLLYSRVGDNWREARKLSVSTQHILVPMHFNLELSKAMVFMDVRMPKFK 765 Query: 1292 WYHKVPVVEIK-------GHLDSMNVSLNQEDLNLL------FRILTENLCEGTEDLDKV 1338 Y K+P++ ++ G ++ + E + + F+I T ++ K+ Sbjct: 766 IYGKLPLISLRISDKKLQGIMELIESIPKPEPVTEVSAPVKSFQIQTSTSLGTSQISQKI 825 Query: 1339 KPRVQETGEIKEPLEISISQDVHDSKNT-------LTTGVEEIR---------SVDIINM 1382 P + E+ E ++ D+ + TGV+ IR SV++ Sbjct: 826 IPLL----ELPSVSEDDSEEEFFDAPCSPLEEPLQFPTGVKSIRTRKLQKQDCSVNMTTF 881 Query: 1383 LLNFEIKEVVVTLMKKSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFDFT 1442 + FE+ +V++ + E+ VL LG E +++TYD+ A A+LK+ ++C ++ Sbjct: 882 KIRFEVPKVLIEFYHLVGDCELSVVEILVLGLGAEIEIRTYDLKANAFLKEFCLKCPEYL 941 Query: 1443 DSKGEPLHIINSSNVTDEPLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLHLE 1502 D +P++++ + + T E LL + KA+ + P+ K+ +++ Q +KV+F+SLD+ LH E Sbjct: 942 DENKKPVYLVTTLDNTMEDLLTLEYVKAEKNVPDLKSTYNNVLQLIKVNFSSLDIHLHTE 1001 Query: 1503 ALLSFMDFLSSAAPFSEPSSSEKESELKPLVGESRSIAVKAVSSNIS-QKDVFDLKITAE 1561 ALL+ +++L + P SE EK + + E + +K ++ +S +D+ L+I AE Sbjct: 1002 ALLNTINYLHNILPQSE----EKSAPVSTTETEDKGDVIKKLALKLSTNEDIITLQILAE 1057 Query: 1562 LNAFNVFVCDQKCNIADIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQSIHKKAVSI 1621 L+ +F+ DQKCNI++IKI G+D+ + ++P +T++ A+L++IIV++ D+ +I+KKAV I Sbjct: 1058 LSCLQIFIQDQKCNISEIKIEGLDSEMIMRPSETEINAKLRNIIVLDSDITAIYKKAVYI 1117 Query: 1622 LGDEVFRFQLTLYPDATEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQT 1681 G EVF F++ Y DAT G AY DM+ VD +++ VGCI++V+V KF S+L F++NFQ Sbjct: 1118 TGKEVFSFKMVSYMDATAGSAYTDMNVVDIQVNLIVGCIEVVFVTKFLYSILAFIDNFQA 1177 Query: 1682 AKEALSTATVQAAERAASSMKDLAQKSFRLLMDINLKAPVIIIPQSSVSPNAVIADLGLI 1741 AK+AL+ ATVQAA AA+ +K+LAQ+S R+ +DIN+KAPV++IPQS VS N +AD GLI Sbjct: 1178 AKQALAEATVQAAGMAATGVKELAQRSSRMALDINIKAPVVVIPQSPVSENVFVADFGLI 1237 Query: 1742 RVENKFSLVPMEHYSLPPVIDKMNIELTQLKLSRTILQASLPQNDIEILKPVNMLLSIQR 1801 + N F ++ S PPVID + I+L++++L R+ Q +++L P+N+ + ++R Sbjct: 1238 TMTNTFHMITESQSSPPPVIDLITIKLSEMRLYRSRFINDAYQEVLDLLLPLNLEVVVER 1297 Query: 1802 NLAAAWYVQIPGMEIKGKLKPMQVALSEDDLTVLMKILLENLG-EASSQPSPTQSVQETV 1860 NL WY ++P + +LKPM+ LS++D+T + K L N+ E SP + + Sbjct: 1298 NLCWEWYQEVPCFNVNAQLKPMEFILSQEDITTIFKTLHGNIWYEKDGSASPAVTKDQYS 1357 Query: 1861 RVRKVDVSSVPDHLKEQEDWTDSKLSMNQIV-----SLQFDFHFESLSIILYNNDINQES 1915 V ++ H T + + ++ +L F + L+++LY+ Q S Sbjct: 1358 ATSGV-TTNASHHSGGATVVTAAVVEVHSRALLVKTTLNISFKTDDLTMVLYSPGPKQAS 1416 Query: 1916 GVAFHNDSFQLGELRLHLMASSGKMFKDGSMNVSVKLKTCTLDDLREGIERATSRMIDRK 1975 + S +L E +L + S+ KM+ DGS S LK C LDD R +++AT RMI Sbjct: 1417 FTDVRDPSLKLAEFKLENIISTLKMYTDGSTFSSFSLKNCILDDKRPHVKKATPRMIGLT 1476 Query: 1976 NDQDNNSSMIDISYKQDKNGSQIDAVLDKLYVCASVEFLMTVADFFIKAVPQSPENVAKE 2035 D M+DI Y++ ++G DAV ++Y+CASVEFL TVA+ F++A A E Sbjct: 1477 VGFDKKD-MMDIKYRKVRDGCVTDAVFQEMYICASVEFLQTVANVFLEAYTTG---TAVE 1532 Query: 2036 TQILPRQTATGKVKIEKDDSVRPNMTLKAMITDPEVVFVASLTKADAPALTASFQCNLSL 2095 T + QT T K ++ +SV+ + +I +PE+VFVA +TK DAPAL + QC + Sbjct: 1533 TSV---QTWTAKEEVPTQESVK--WEINVIIKNPEIVFVADMTKNDAPALVITTQCEICY 1587 Query: 2096 STSKLEQMMEASVRDLKVLACPFLREKRGKNITTVLQPCSLFMEKCTWASGKQNINIMVK 2155 + M A+++DL+V ACPFL KR ITTVLQPC LF + + Q I++ VK Sbjct: 1588 KGNLENSTMTAAIKDLQVRACPFLPVKRKGKITTVLQPCDLFYQTTQKGTDPQVIDMSVK 1647 Query: 2156 EFIIKISPIILNTVLTIMAALSPKTKEDGSKDTSKEMENLWGIKSINDYNTWFLGVDTAT 2215 +K+SP+I+NT++TI +AL TKE ++T+ +LW K WFL T Sbjct: 1648 SLTLKVSPVIINTMITITSALYT-TKETIPEETASSTAHLWEKKDTKTLKMWFLEESNET 1706 Query: 2216 EITESFKGI--EHSLIEENCGVVVESIQVTLECGLGHRTVPLLLAESKFSGNIKNWTSLM 2273 E + + +I+ N ++SI + LE G+GHRTVP+LLA+S+FSG KNW+SL+ Sbjct: 1707 EKIAPTTELVPKGEMIKMN----IDSIFIVLEAGIGHRTVPMLLAKSRFSGEGKNWSSLI 1762 Query: 2274 AAVADVTLQVHYYNEIHAVWEPLIE-----RVEGKRQWNLRLDVKKNP---VQDKSLLPG 2325 + L+VHYYNE+ VWEPL+E + E R WNL + +KK + + Sbjct: 1763 NLHCQLELEVHYYNEMFGVWEPLLEPLEIDQTEDFRPWNLGIKMKKKAKMAIVESDPEEE 1822 Query: 2326 DDFIPEPQMAIHISSGNTMNITISKSCLNVFNNLAKGFSEG-TASTFDYSLKDRAPFTVK 2384 + +PE + I S + +NIT+SK L + NNL K F+E T S+ D+ +KD APF + Sbjct: 1823 NYKVPEYKTVISFHSKDQLNITLSKCGLVMLNNLVKAFTEAATGSSADF-VKDLAPFMIL 1881 Query: 2385 NAVGVPIKVKPNCNLRVMGFPEKSDIFDVDAGQNLELEYASMVPSSQGNLSILSRQESSF 2444 N++G+ I V P+ + V+ P + + G++L ++Y + N ++ S Sbjct: 1882 NSLGLTISVSPSDSFSVLNIPMAKS-YVLKNGESLSMDYIRTKDNDHFNA--MTSLSSKL 1938 Query: 2445 FTLTIVPHGYTEVANIPVARPGRRLYNVRNPNASHSDSVLVQIDATEGNKVITLRSPLQI 2504 F + + P ++ IP+ + GRRLY VR+ + S++ QID EG+K +T+RSP+QI Sbjct: 1939 FFILLTPVNHSTADKIPLTKVGRRLYTVRHRESGVERSIVCQIDTVEGSKKVTIRSPVQI 1998 Query: 2505 KNHFSIAFIIYKFVKNVKLLERIGIARPEEEFHVPLDSYRCQLFIQPAGILEHQYKESTT 2564 +NHFS+ +Y+ +G A PE EF++PL SYR +F++P +Q E Sbjct: 1999 RNHFSVPLSVYEGDT------LLGTASPENEFNIPLGSYRSFIFLKPEDE-NYQMCEGID 2051 Query: 2565 YISWKEELHRSREVRCMLQCPSVEVSFLPLIVNTVALPDELSYICTHGED-WDVAYIIHL 2623 + EE+ ++ +C S S ++N V D L+ + + ED WD+ YI+HL Sbjct: 2052 F----EEIIKNDGALLKKKCRSKNPSKESFLINIVPEKDNLTSLSVYSEDGWDLPYIMHL 2107 Query: 2624 YPSLTLRNLLPYSLRYLLEGTAET-HELAEGSTADVLHSRISGEIMELVLVKYQGKNWNG 2682 +P + LRNLLPY + Y +EG + L+EG +A + +++ + L L+ Y +W Sbjct: 2108 WPPILLRNLLPYKIAYYIEGIENSVFTLSEGHSAQICTAQLGKARLHLKLLDYLNHDWKS 2167 Query: 2683 HFRIRDTLPEFFPVCFSS-DSTEVTTVDLSVHVRRIGSRMVLSVFSPYWLINKTTRVLQY 2741 + I+ + V F+ E T +D++VH+ + V++ SPYW++NKT R+LQY Sbjct: 2168 EYHIKPNQQDISFVSFTCVTEMEKTDLDIAVHMTYNTGQTVVAFHSPYWMVNKTGRMLQY 2227 Query: 2742 RSEDIHVKHPADFRDIILFSFKKKNIFTKNKVQLKISTSAWSSSFSLDTVGSYGCVKCPA 2801 +++ IH KHP +++ +LFSF+ + F NKVQL ++ S S+ FS+DTVGS+G VKC Sbjct: 2228 KADGIHRKHPPNYKKPVLFSFQPNHFFNNNKVQLMVTDSELSNQFSIDTVGSHGAVKCKG 2287 Query: 2802 NNMEYLVGVSIKMSSFNLSRIVTLTPFCTIANKSSLELEVGEIASDGSMPTNKWNYIASS 2861 M+Y VGV+I +SSFN++RIVT TPF I NKS + V E +D KW + Sbjct: 2288 LKMDYQVGVTIDLSSFNITRIVTFTPFYMIKNKSKYHISVAEEGND------KWLSLDLE 2341 Query: 2862 ECLPFWPESLSGKLCVRVVGCEGSSKPFFYNRQDNGTLLSLEDLNGGILVDVNTAEHSTV 2921 +C+PFWPE S KL ++V E K ++N+Q+N LL L++ GGI+ +VN AEHSTV Sbjct: 2342 QCIPFWPEYASSKLLIQVERSEDPPKRIYFNKQENCILLRLDNELGGIIAEVNLAEHSTV 2401 Query: 2922 ITFSDYHEGSAPALIMNHTPWDILTYKQSGSPE-EMVLLPRQARLFAWADPTGTRKLTWT 2980 ITF DYH+G+A L++NHT +++ Y QS E E L P +A + WADP G+R+L W Sbjct: 2402 ITFLDYHDGAATFLLINHTKNELVQYNQSSLSEIEDSLPPGKAVFYTWADPVGSRRLKWR 2461 Query: 2981 YAANVGEHDLLKDGCGQFPYDANIQ-IHWVSFLDGRQRVLLFTDDVALVSKALQAEEMEQ 3039 + GE D P D + I+ VSF +G QR++LFT+D + ++E+ E Sbjct: 2462 CRKSHGEVTQKDDM--MMPIDLGEKTIYLVSFFEGLQRIILFTEDPRVFKVTYESEKAEL 2519 Query: 3040 ADYEITLSLHSLGLSLVNNESKQEVSYIGITSSGVVWEVKPKQK--WKPFSQKQIILLEQ 3097 A+ EI ++L +G+SLVNN +KQEV+YIGITSS VVWE KPK+K WKP S K LE+ Sbjct: 2520 AEQEIAVALQDVGISLVNNYTKQEVAYIGITSSDVVWETKPKKKARWKPMSVKHTEKLER 2579 Query: 3098 SYQKHQISR--DHGWIKLDNNFEVNFDKDPMEMRL--PIRSPIKRDFLSGIQIEFKQSSH 3153 ++++ S + I+LD N V M++ P ++R++L +++E+ S+H Sbjct: 2580 EFKEYTESSPSEDKVIQLDTNVPVRLTPTGHNMKILQPHVIALRRNYLPALKVEYNTSAH 2639 Query: 3154 QRSLRARLYWLQVDNQLPGAMFPVVFHPVAPPKSIALDSEPKPFIDVSVITRFNEYSKVL 3213 Q S R ++Y +Q+ NQ+ GA+FP VF+PV PPKS+ +DS PKPF DVS++ R +S++ Sbjct: 2640 QSSFRIQIYRIQIQNQIHGAVFPFVFYPVKPPKSVTMDSAPKPFTDVSIVMRSAGHSQIS 2699 Query: 3214 QFKYFMVLIQEMALKIDQGFLGAIIALFTPTTDPEAERRRTKLIQQDIDALNAELMETSM 3273 + KYF VLIQEM L++D GF+ A+ L T E +L +DI+A E S+ Sbjct: 2700 RIKYFKVLIQEMDLRLDLGFIYALTDLMTEAE--VTENTEVELFHKDIEAFKEEYKTASL 2757 Query: 3274 TDMSILSFFEHFHISPVKLHLSLSLGSGGEESDKEKQE--MFAVHSVNLLLKSIGATLTD 3331 D S +S +E+FHISP+KLHLS+SL SG EE+ KQ + VHS+NLLLKSIGATLTD Sbjct: 2758 VDQSQVSLYEYFHISPIKLHLSVSLSSGREEAKDSKQNGGLIPVHSLNLLLKSIGATLTD 2817 Query: 3332 VDDLIFKLAYYEIRYQFYKRDQLIWSVVRHYSEQFLKQMYVLVLGLDVLGNPFGLIRGLS 3391 V D++FKLA++E+ YQF+ L V+RHYS+Q +KQMYVL+LGLDVLGNPFGLIR S Sbjct: 2818 VQDVVFKLAFFELNYQFHTTSDLQSEVIRHYSKQAIKQMYVLILGLDVLGNPFGLIREFS 2877 Query: 3392 EGVEALFYEPFQGAVQGPEEFAEGLVIGVRSLFGHTVGGAAGVVSRITGSVGKGLAAITM 3451 EGVEA FYEP+QGA+QGPEEF EG+ +G+++L G VGG AG S+ITG++ KG+AA+TM Sbjct: 2878 EGVEAFFYEPYQGAIQGPEEFVEGMALGLKALVGGAVGGLAGAASKITGAMAKGVAAMTM 2937 Query: 3452 DKEYQQKRREELSRQPRDFGDSLARGGKGFLRGVVGGVTGIITKPVEGAKKEGAAGFFKG 3511 D++YQQKRRE +++QP F + + RGGKG + G V G+TGI+TKP++GA+K GAAGFFKG Sbjct: 2938 DEDYQQKRREAMNKQPAGFREGITRGGKGLVSGFVSGITGIVTKPIKGAQKGGAAGFFKG 2997 Query: 3512 IGKGLVGAVARPTGGIVDMASSTFQGIQRAAESTEEVSSLRPPRLIHEDGIIRPYDRQES 3571 +GKGLVGAVARPTGGI+DMASSTFQGI+RA E T EV SLRPPR +EDG+IRPY ++ Sbjct: 2998 VGKGLVGAVARPTGGIIDMASSTFQGIKRATE-TSEVESLRPPRFFNEDGVIRPYRLRDG 3056 Query: 3572 EGSDLLE 3578 G+ +L+ Sbjct: 3057 TGNQMLQ 3063 Score = 1149 bits (2971), Expect = 0.0 Identities = 616/1353 (45%), Positives = 889/1353 (65%), Gaps = 39/1353 (2%) Query: 1 MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAG 60 MV ESVV D+LNRFLGDYV +L+ SQL LGIW G VAL NLQIKENALS+LDVPFKVK G Sbjct: 1 MVFESVVVDVLNRFLGDYVVDLDTSQLSLGIWKGAVALKNLQIKENALSQLDVPFKVKVG 60 Query: 61 QIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEE 120 I L L IPWKNLY + V A LE +YLL+VP + IKYD +KEEK L + KQ+EL RIEE Sbjct: 61 HIGNLKLIIPWKNLYTQPVEAVLEEIYLLIVPSSRIKYDPLKEEKQLMEAKQQELKRIEE 120 Query: 121 ALQKAAEKDKPKEAKKDTFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLG 180 A QK ++++ K+DTF EKL TQ+IKN+QVKI+ IHI+YEDD+T+ +PLSFG++L Sbjct: 121 AKQKVVDQEQHLPEKQDTFAEKLVTQIIKNLQVKISSIHIRYEDDITNRDKPLSFGISLQ 180 Query: 181 ELSLLTANEHWTPCILNEADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILDQLKNEIL 240 LS+ T +++W PC+ +E +K++ KLIRLD+L AYWNV M Y + LD LKN I+ Sbjct: 181 NLSMQTTDQYWVPCLHDETEKLVRKLIRLDNLFAYWNVKSQMFYLSDYDNSLDDLKNGIV 240 Query: 241 TSGNIPPNYQYIFQPISASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKPQYLSMID 300 +P Y ++F+PISA+AKL MN ++ + PK++ IE+ NIAIE KPQY S+++ Sbjct: 241 NENIVPEGYDFVFRPISANAKLVMNRRSDFDFSAPKINLEIELHNIAIEFNKPQYFSIME 300 Query: 301 LLESVDYMVRNAPYRKYKPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIKKHRQ 360 LLESVD M +N PYRK+KP +PLH + R WW YAI VLEV++ MWSW +I+KHRQ Sbjct: 301 LLESVDMMAQNLPYRKFKPDVPLHHHAREWWAYAIHGVLEVNVCPRLWMWSWKHIRKHRQ 360 Query: 361 LLKSYKIAYKNKLTQSKVSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKS 420 +K YK YK KLT K E+ +++LEKTLDVFNI +ARQ A+VEV ++G K+ K+ Sbjct: 361 KVKQYKELYKKKLTSKKPPGELLVSLEELEKTLDVFNITIARQTAEVEVKKAGYKIYKEG 420 Query: 421 ADTGEKRGGWFSGLWGKKESKKKDEE-SLIPETIDDLMTPEEKDKLFTAIGYSESTHNLT 479 E GWFS LW E +++ + PET+++++TPEEK L+ AIGYSE+ + T Sbjct: 421 VKDPEDNKGWFSWLWSWSEQNTNEQQPDVQPETLEEMLTPEEKALLYEAIGYSETAVDPT 480 Query: 480 LPKQYVAHIMTLKLVSTSVTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVEAKLEHW 539 L K + A + L S S+ +REN PE++ I I T + QRPGAQA+K E K++ + Sbjct: 481 LLKTFEALKFFVHLKSMSIVLRENHQKPELVDIVIEEFSTLIVQRPGAQAIKFETKIDSF 540 Query: 540 YITGLRQQDIVPSLVASIGDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIYDAKTVN 599 +ITGL P L++S+ D SL +I FE NP D Q I++++P+E+IYDA+TVN Sbjct: 541 HITGLPDNSEKPRLLSSL-DDAMSLFQITFEINPLDETVSQRCIIEAEPLEIIYDARTVN 599 Query: 600 AVVEFFQSNKGLDLEQITSATLMKLEEIKERTATGLTHIIETRKVLDLRINLKPSYLVVP 659 ++VEFF+ K + L Q+T+ATL KLEE + +TATGL +IIET+KVLDL+INLK SY++VP Sbjct: 600 SIVEFFRPPKEVHLAQLTAATLTKLEEFRSKTATGLLYIIETQKVLDLKINLKASYIIVP 659 Query: 660 QTGFHHEKSDLLILDFGTFQLNSKDQGL---QKTTNSSLEEIMDKAYDKFDVEIKNVQLL 716 Q G S+LL+LD G ++ SK + K ++L+EIMD+AYD FD+++ +VQLL Sbjct: 660 QDGIFSPTSNLLLLDLGHLKVTSKSRSELPDVKQGEANLKEIMDRAYDSFDIQLTSVQLL 719 Query: 717 FARAEETWKKCRFQHPSTMHILQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVRISD 776 ++R + W++ R ST HIL PM ++EL+KAMV D+RM +FK+ G LPL+ +RISD Sbjct: 720 YSRVGDNWREARKLSVSTQHILVPMHFNLELSKAMVFMDVRMPKFKIYGKLPLISLRISD 779 Query: 777 QKMKDVLYLMNSIPLPQKSSAQSPERQVSS-IPIISGGTKGLLGTSLLLDTV-------- 827 +K++ ++ L+ SIP P+ P +VS+ + T LGTS + + Sbjct: 780 KKLQGIMELIESIPKPE------PVTEVSAPVKSFQIQTSTSLGTSQISQKIIPLLELPS 833 Query: 828 --ESESDDEYFDAEDGE-------PQTCKSMKGSELKKAAEVPNEELINLLLKFEIKEVI 878 E +S++E+FDA P KS++ +L+K + + + ++FE+ +V+ Sbjct: 834 VSEDDSEEEFFDAPCSPLEEPLQFPTGVKSIRTRKLQK--QDCSVNMTTFKIRFEVPKVL 891 Query: 879 LEFTKQQKE-EDTILVFNVTQLGTEATMRTFDLTVVSYLKKISLDYHEIEGSKRKPLHLI 937 +EF + E +++ V LG E +RT+DL ++LK+ L E +KP++L+ Sbjct: 892 IEFYHLVGDCELSVVEILVLGLGAEIEIRTYDLKANAFLKEFCLKCPEYLDENKKPVYLV 951 Query: 938 SSSDKPGLDLLKVEYIKADKNGPSFQTAFGKTEQTVKVAFSSLNLLLQTQALVASINYLT 997 ++ D DLL +EY+KA+KN P ++ + Q +KV FSSL++ L T+AL+ +INYL Sbjct: 952 TTLDNTMEDLLTLEYVKAEKNVPDLKSTYNNVLQLIKVNFSSLDIHLHTEALLNTINYLH 1011 Query: 998 TIIP-SDDQSISVAKEVQISTEKQQKNSTLPK-AIVSSRDSDIIDFRLFAKLNAFCVIVC 1055 I+P S+++S V+ +TE + K + K A+ S + DII ++ A+L+ + + Sbjct: 1012 NILPQSEEKSAPVS-----TTETEDKGDVIKKLALKLSTNEDIITLQILAELSCLQIFIQ 1066 Query: 1056 NEKNNIAEIKIQGLDSSLSLQSRKQSLFARLENIIVTDVDPKTVHKKAVSIMGNEVFRFN 1115 ++K NI+EIKI+GLDS + ++ + + A+L NIIV D D ++KKAV I G EVF F Sbjct: 1067 DQKCNISEIKIEGLDSEMIMRPSETEINAKLRNIIVLDSDITAIYKKAVYITGKEVFSFK 1126 Query: 1116 LDLYPDATEGDLYTDMSKVDGVLSLNVGCIQIVYLHKFLMSLLNFLNNFQTAKESLSAAT 1175 + Y DAT G YTDM+ VD ++L VGCI++V++ KFL S+L F++NFQ AK++L+ AT Sbjct: 1127 MVSYMDATAGSAYTDMNVVDIQVNLIVGCIEVVFVTKFLYSILAFIDNFQAAKQALAEAT 1186 Query: 1176 AQAAERAATSVKDLAQRSFRVSINIDLKAPVIVIPQSSISTNAVVVDLGLIRVHNQFSLV 1235 QAA AAT VK+LAQRS R++++I++KAPV+VIPQS +S N V D GLI + N F ++ Sbjct: 1187 VQAAGMAATGVKELAQRSSRMALDINIKAPVVVIPQSPVSENVFVADFGLITMTNTFHMI 1246 Query: 1236 SDEDYLNPPVIDRMDVQLTKLTLYRTVIQPGIYHPDIQLLHPINLEFLVNRNLAASWYHK 1295 ++ PPVID + ++L+++ LYR+ Y + LL P+NLE +V RNL WY + Sbjct: 1247 TESQSSPPPVIDLITIKLSEMRLYRSRFINDAYQEVLDLLLPLNLEVVVERNLCWEWYQE 1306 Query: 1296 VPVVEIKGHLDSMNVSLNQEDLNLLFRILTENL 1328 VP + L M L+QED+ +F+ L N+ Sbjct: 1307 VPCFNVNAQLKPMEFILSQEDITTIFKTLHGNI 1339 Score = 54.7 bits (130), Expect = 2e-06 Identities = 82/394 (20%), Positives = 175/394 (44%), Gaps = 57/394 (14%) Query: 1517 FSEPSSSEKESELKP------LVGESRSIAVKAVSSNISQKD-----VFD-LKITAELNA 1564 +SE +++E++ +++P L E +++ +A+ + + D F+ LK L + Sbjct: 437 WSEQNTNEQQPDVQPETLEEMLTPEEKALLYEAIGYSETAVDPTLLKTFEALKFFVHLKS 496 Query: 1565 FNVFVCD--QKCNIADIKIHGMDASISVKPKQTDVF--ARLKDIIVMNVDLQSIHKKAVS 1620 ++ + + QK + DI I I +P + ++ + + S + +S Sbjct: 497 MSIVLRENHQKPELVDIVIEEFSTLIVQRPGAQAIKFETKIDSFHITGLPDNSEKPRLLS 556 Query: 1621 ILGDEVFRFQLTLYPDATEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQ 1680 L D + FQ+T + + V + + ++I+Y + S++ F F+ Sbjct: 557 SLDDAMSLFQITFEINPLD-------ETVSQRCIIEAEPLEIIYDARTVNSIVEF---FR 606 Query: 1681 TAKEA----LSTATVQAAE----RAASSMKDLAQKSFRLLMDINLKAPVIIIPQSSV--- 1729 KE L+ AT+ E + A+ + + + L + INLKA II+PQ + Sbjct: 607 PPKEVHLAQLTAATLTKLEEFRSKTATGLLYIIETQKVLDLKINLKASYIIVPQDGIFSP 666 Query: 1730 SPNAVIADLGLIRVENK----FSLVPMEHYSLPPVIDK----MNIELTQLKLSRTIL--- 1778 + N ++ DLG ++V +K V +L ++D+ +I+LT ++L + + Sbjct: 667 TSNLLLLDLGHLKVTSKSRSELPDVKQGEANLKEIMDRAYDSFDIQLTSVQLLYSRVGDN 726 Query: 1779 ---QASLPQNDIEILKPVNMLLSIQRNLAAAWYVQIPGMEIKGKLKPMQVALSEDDLTVL 1835 L + IL P++ L + + + V++P +I GKL + + +S+ L + Sbjct: 727 WREARKLSVSTQHILVPMHFNLELSKAM-VFMDVRMPKFKIYGKLPLISLRISDKKLQGI 785 Query: 1836 MKILLENLGEASSQPSPTQSVQETVRVRKVDVSS 1869 M+++ E+ +P P V V+ ++ S+ Sbjct: 786 MELI-----ESIPKPEPVTEVSAPVKSFQIQTST 814 >gi|66346674 vacuolar protein sorting 13A isoform A [Homo sapiens] Length = 3174 Score = 1679 bits (4347), Expect = 0.0 Identities = 982/2527 (38%), Positives = 1504/2527 (59%), Gaps = 145/2527 (5%) Query: 1145 IQIVYLHKFLMSLLNFLNNFQTAKE----SLSAATAQAAE----RAATSVKDLAQRSFRV 1196 ++I+Y + + S++ F F+ KE L+AAT E + AT + + + + Sbjct: 589 LEIIYDARTVNSIVEF---FRPPKEVHLAQLTAATLTKLEEFRSKTATGLLYIIETQKVL 645 Query: 1197 SINIDLKAPVIVIPQSSI---STNAVVVDLGLIRV----HNQFSLVSDEDYLNPPVIDR- 1248 + I+LKA I++PQ I ++N +++DLG ++V ++ V + ++DR Sbjct: 646 DLKINLKASYIIVPQDGIFSPTSNLLLLDLGHLKVTSKSRSELPDVKQGEANLKEIMDRA 705 Query: 1249 ---MDVQLTKLTL--------YRTVIQPGIYHPDIQLLHPINLE------FLVNRNLAAS 1291 D+QLT + L +R + + I + NLE F+ R Sbjct: 706 YDSFDIQLTSVQLLYSRVGDNWREARKLSVSTQHILVPMHFNLELSKAMVFMDVRMPKFK 765 Query: 1292 WYHKVPVVEIK-------GHLDSMNVSLNQEDLNLL------FRILTENLCEGTEDLDKV 1338 Y K+P++ ++ G ++ + E + + F+I T ++ K+ Sbjct: 766 IYGKLPLISLRISDKKLQGIMELIESIPKPEPVTEVSAPVKSFQIQTSTSLGTSQISQKI 825 Query: 1339 KPRVQETGEIKEPLEISISQDVHDSKNT-------LTTGVEEIR---------SVDIINM 1382 P + E+ E ++ D+ + TGV+ IR SV++ Sbjct: 826 IPLL----ELPSVSEDDSEEEFFDAPCSPLEEPLQFPTGVKSIRTRKLQKQDCSVNMTTF 881 Query: 1383 LLNFEIKEVVVTLMKKSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFDFT 1442 + FE+ +V++ + E+ VL LG E +++TYD+ A A+LK+ ++C ++ Sbjct: 882 KIRFEVPKVLIEFYHLVGDCELSVVEILVLGLGAEIEIRTYDLKANAFLKEFCLKCPEYL 941 Query: 1443 DSKGEPLHIINSSNVTDEPLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLHLE 1502 D +P++++ + + T E LL + KA+ + P+ K+ +++ Q +KV+F+SLD+ LH E Sbjct: 942 DENKKPVYLVTTLDNTMEDLLTLEYVKAEKNVPDLKSTYNNVLQLIKVNFSSLDIHLHTE 1001 Query: 1503 ALLSFMDFLSSAAPFSEPSSSEKESELKPLVGESRSIAVKAVSSNIS-QKDVFDLKITAE 1561 ALL+ +++L + P SE EK + + E + +K ++ +S +D+ L+I AE Sbjct: 1002 ALLNTINYLHNILPQSE----EKSAPVSTTETEDKGDVIKKLALKLSTNEDIITLQILAE 1057 Query: 1562 LNAFNVFVCDQKCNIADIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQSIHKKAVSI 1621 L+ +F+ DQKCNI++IKI G+D+ + ++P +T++ A+L++IIV++ D+ +I+KKAV I Sbjct: 1058 LSCLQIFIQDQKCNISEIKIEGLDSEMIMRPSETEINAKLRNIIVLDSDITAIYKKAVYI 1117 Query: 1622 LGDEVFRFQLTLYPDATEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQT 1681 G EVF F++ Y DAT G AY DM+ VD +++ VGCI++V+V KF S+L F++NFQ Sbjct: 1118 TGKEVFSFKMVSYMDATAGSAYTDMNVVDIQVNLIVGCIEVVFVTKFLYSILAFIDNFQA 1177 Query: 1682 AKEALSTATVQAAERAASSMKDLAQKSFRLLMDINLKAPVIIIPQSSVSPNAVIADLGLI 1741 AK+AL+ ATVQAA AA+ +K+LAQ+S R+ +DIN+KAPV++IPQS VS N +AD GLI Sbjct: 1178 AKQALAEATVQAAGMAATGVKELAQRSSRMALDINIKAPVVVIPQSPVSENVFVADFGLI 1237 Query: 1742 RVENKFSLVPMEHYSLPPVIDKMNIELTQLKLSRTILQASLPQNDIEILKPVNMLLSIQR 1801 + N F ++ S PPVID + I+L++++L R+ Q +++L P+N+ + ++R Sbjct: 1238 TMTNTFHMITESQSSPPPVIDLITIKLSEMRLYRSRFINDAYQEVLDLLLPLNLEVVVER 1297 Query: 1802 NLAAAWYVQIPGMEIKGKLKPMQVALSEDDLTVLMKILLENLG-EASSQPSPTQSVQETV 1860 NL WY ++P + +LKPM+ LS++D+T + K L N+ E SP + + Sbjct: 1298 NLCWEWYQEVPCFNVNAQLKPMEFILSQEDITTIFKTLHGNIWYEKDGSASPAVTKDQYS 1357 Query: 1861 RVRKVDVSSVPDHLKEQEDWTDSKLSMNQIV-----SLQFDFHFESLSIILYNNDINQES 1915 V ++ H T + + ++ +L F + L+++LY+ Q S Sbjct: 1358 ATSGV-TTNASHHSGGATVVTAAVVEVHSRALLVKTTLNISFKTDDLTMVLYSPGPKQAS 1416 Query: 1916 GVAFHNDSFQLGELRLHLMASSGKMFKDGSMNVSVKLKTCTLDDLREGIERATSRMIDRK 1975 + S +L E +L + S+ KM+ DGS S LK C LDD R +++AT RMI Sbjct: 1417 FTDVRDPSLKLAEFKLENIISTLKMYTDGSTFSSFSLKNCILDDKRPHVKKATPRMIGLT 1476 Query: 1976 NDQDNNSSMIDISYKQDKNGSQIDAVLDKLYVCASVEFLMTVADFFIKAVPQSPENVAKE 2035 D M+DI Y++ ++G DAV ++Y+CASVEFL TVA+ F++A A E Sbjct: 1477 VGFDKKD-MMDIKYRKVRDGCVTDAVFQEMYICASVEFLQTVANVFLEAYTTG---TAVE 1532 Query: 2036 TQILPRQTATGKVKIEKDDSVRPNMTLKAMITDPEVVFVASLTKADAPALTASFQCNLSL 2095 T + QT T K ++ +SV+ + +I +PE+VFVA +TK DAPAL + QC + Sbjct: 1533 TSV---QTWTAKEEVPTQESVK--WEINVIIKNPEIVFVADMTKNDAPALVITTQCEICY 1587 Query: 2096 STSKLEQMMEASVRDLKVLACPFLREKRGKNITTVLQPCSLFMEKCTWASGKQNINIMVK 2155 + M A+++DL+V ACPFL KR ITTVLQPC LF + + Q I++ VK Sbjct: 1588 KGNLENSTMTAAIKDLQVRACPFLPVKRKGKITTVLQPCDLFYQTTQKGTDPQVIDMSVK 1647 Query: 2156 EFIIKISPIILNTVLTIMAALSPKTKEDGSKDTSKEMENLWGIKSINDYNTWFLGVDTAT 2215 +K+SP+I+NT++TI +AL TKE ++T+ +LW K WFL T Sbjct: 1648 SLTLKVSPVIINTMITITSALYT-TKETIPEETASSTAHLWEKKDTKTLKMWFLEESNET 1706 Query: 2216 EITESFKGI--EHSLIEENCGVVVESIQVTLECGLGHRTVPLLLAESKFSGNIKNWTSLM 2273 E + + +I+ N ++SI + LE G+GHRTVP+LLA+S+FSG KNW+SL+ Sbjct: 1707 EKIAPTTELVPKGEMIKMN----IDSIFIVLEAGIGHRTVPMLLAKSRFSGEGKNWSSLI 1762 Query: 2274 AAVADVTLQVHYYNEIHAVWEPLIE-----RVEGKRQWNLRLDVKKNP---VQDKSLLPG 2325 + L+VHYYNE+ VWEPL+E + E R WNL + +KK + + Sbjct: 1763 NLHCQLELEVHYYNEMFGVWEPLLEPLEIDQTEDFRPWNLGIKMKKKAKMAIVESDPEEE 1822 Query: 2326 DDFIPEPQMAIHISSGNTMNITISKSCLNVFNNLAKGFSEG-TASTFDYSLKDRAPFTVK 2384 + +PE + I S + +NIT+SK L + NNL K F+E T S+ D+ +KD APF + Sbjct: 1823 NYKVPEYKTVISFHSKDQLNITLSKCGLVMLNNLVKAFTEAATGSSADF-VKDLAPFMIL 1881 Query: 2385 NAVGVPIKVKPNCNLRVMGFPEKSDIFDVDAGQNLELEYASMVPSSQGNLSILSRQESSF 2444 N++G+ I V P+ + V+ P + + G++L ++Y + N ++ S Sbjct: 1882 NSLGLTISVSPSDSFSVLNIPMAKS-YVLKNGESLSMDYIRTKDNDHFNA--MTSLSSKL 1938 Query: 2445 FTLTIVPHGYTEVANIPVARPGRRLYNVRNPNASHSDSVLVQIDATEGNKVITLRSPLQI 2504 F + + P ++ IP+ + GRRLY VR+ + S++ QID EG+K +T+RSP+QI Sbjct: 1939 FFILLTPVNHSTADKIPLTKVGRRLYTVRHRESGVERSIVCQIDTVEGSKKVTIRSPVQI 1998 Query: 2505 KNHFSIAFIIYKFVKNVKLLERIGIARPEEEFHVPLDSYRCQLFIQPAGILEHQYKESTT 2564 +NHFS+ +Y+ +G A PE EF++PL SYR +F++P +Q E Sbjct: 1999 RNHFSVPLSVYEGDT------LLGTASPENEFNIPLGSYRSFIFLKPEDE-NYQMCEGID 2051 Query: 2565 YISWKEELHRSREVRCMLQCPSVEVSFLPLIVNTVALPDELSYICTHGED-WDVAYIIHL 2623 + EE+ ++ +C S S ++N V D L+ + + ED WD+ YI+HL Sbjct: 2052 F----EEIIKNDGALLKKKCRSKNPSKESFLINIVPEKDNLTSLSVYSEDGWDLPYIMHL 2107 Query: 2624 YPSLTLRNLLPYSLRYLLEGTAET-HELAEGSTADVLHSRISGEIMELVLVKYQGKNWNG 2682 +P + LRNLLPY + Y +EG + L+EG +A + +++ + L L+ Y +W Sbjct: 2108 WPPILLRNLLPYKIAYYIEGIENSVFTLSEGHSAQICTAQLGKARLHLKLLDYLNHDWKS 2167 Query: 2683 HFRIRDTLPEFFPVCFSS-DSTEVTTVDLSVHVRRIGSRMVLSVFSPYWLINKTTRVLQY 2741 + I+ + V F+ E T +D++VH+ + V++ SPYW++NKT R+LQY Sbjct: 2168 EYHIKPNQQDISFVSFTCVTEMEKTDLDIAVHMTYNTGQTVVAFHSPYWMVNKTGRMLQY 2227 Query: 2742 RSEDIHVKHPADFRDIILFSFKKKNIFTKNKVQLKISTSAWSSSFSLDTVGSYGCVKCPA 2801 +++ IH KHP +++ +LFSF+ + F NKVQL ++ S S+ FS+DTVGS+G VKC Sbjct: 2228 KADGIHRKHPPNYKKPVLFSFQPNHFFNNNKVQLMVTDSELSNQFSIDTVGSHGAVKCKG 2287 Query: 2802 NNMEYLVGVSIKMSSFNLSRIVTLTPFCTIANKSSLELEVGEIASDGSMPTNKWNYIASS 2861 M+Y VGV+I +SSFN++RIVT TPF I NKS + V E +D KW + Sbjct: 2288 LKMDYQVGVTIDLSSFNITRIVTFTPFYMIKNKSKYHISVAEEGND------KWLSLDLE 2341 Query: 2862 ECLPFWPESLSGKLCVRVVGCEGSSKPFFYNRQDNGTLLSLEDLNGGILVDVNTAEHSTV 2921 +C+PFWPE S KL ++V E K ++N+Q+N LL L++ GGI+ +VN AEHSTV Sbjct: 2342 QCIPFWPEYASSKLLIQVERSEDPPKRIYFNKQENCILLRLDNELGGIIAEVNLAEHSTV 2401 Query: 2922 ITFSDYHEGSAPALIMNHTPWDILTYKQSGSPE-EMVLLPRQARLFAWADPTGTRKLTWT 2980 ITF DYH+G+A L++NHT +++ Y QS E E L P +A + WADP G+R+L W Sbjct: 2402 ITFLDYHDGAATFLLINHTKNELVQYNQSSLSEIEDSLPPGKAVFYTWADPVGSRRLKWR 2461 Query: 2981 YAANVGEHDLLKDGCGQFPYDANIQ-IHWVSFLDGRQRVLLFTDDVALVSKALQAEEMEQ 3039 + GE D P D + I+ VSF +G QR++LFT+D + ++E+ E Sbjct: 2462 CRKSHGEVTQKDDM--MMPIDLGEKTIYLVSFFEGLQRIILFTEDPRVFKVTYESEKAEL 2519 Query: 3040 ADYEITLSLHSLGLSLVNNESKQEVSYIGITSSGVVWEVKPKQK--WKPFSQKQIILLEQ 3097 A+ EI ++L +G+SLVNN +KQEV+YIGITSS VVWE KPK+K WKP S K LE+ Sbjct: 2520 AEQEIAVALQDVGISLVNNYTKQEVAYIGITSSDVVWETKPKKKARWKPMSVKHTEKLER 2579 Query: 3098 SYQKHQISR--DHGWIKLDNNFEVNFDKDPMEMRL--PIRSPIKRDFLSGIQIEFKQSSH 3153 ++++ S + I+LD N V M++ P ++R++L +++E+ S+H Sbjct: 2580 EFKEYTESSPSEDKVIQLDTNVPVRLTPTGHNMKILQPHVIALRRNYLPALKVEYNTSAH 2639 Query: 3154 QRSLRARLYWLQVDNQLPGAMFPVVFHPVAPPKSIALDSEPKPFIDVSVITRFNEYSKVL 3213 Q S R ++Y +Q+ NQ+ GA+FP VF+PV PPKS+ +DS PKPF DVS++ R +S++ Sbjct: 2640 QSSFRIQIYRIQIQNQIHGAVFPFVFYPVKPPKSVTMDSAPKPFTDVSIVMRSAGHSQIS 2699 Query: 3214 QFKYFMVLIQEMALKIDQGFLGAIIALFTPTTDPEAERRRTKLIQQDIDALNAELMETSM 3273 + KYF VLIQEM L++D GF+ A+ L T E +L +DI+A E S+ Sbjct: 2700 RIKYFKVLIQEMDLRLDLGFIYALTDLMTEAE--VTENTEVELFHKDIEAFKEEYKTASL 2757 Query: 3274 TDMSILSFFEHFHISPVKLHLSLSLGSGGEESDKEKQE--MFAVHSVNLLLKSIGATLTD 3331 D S +S +E+FHISP+KLHLS+SL SG EE+ KQ + VHS+NLLLKSIGATLTD Sbjct: 2758 VDQSQVSLYEYFHISPIKLHLSVSLSSGREEAKDSKQNGGLIPVHSLNLLLKSIGATLTD 2817 Query: 3332 VDDLIFKLAYYEIRYQFYKRDQLIWSVVRHYSEQFLKQMYVLVLGLDVLGNPFGLIRGLS 3391 V D++FKLA++E+ YQF+ L V+RHYS+Q +KQMYVL+LGLDVLGNPFGLIR S Sbjct: 2818 VQDVVFKLAFFELNYQFHTTSDLQSEVIRHYSKQAIKQMYVLILGLDVLGNPFGLIREFS 2877 Query: 3392 EGVEALFYEPFQGAVQGPEEFAEGLVIGVRSLFGHTVGGAAGVVSRITGSVGKGLAAITM 3451 EGVEA FYEP+QGA+QGPEEF EG+ +G+++L G VGG AG S+ITG++ KG+AA+TM Sbjct: 2878 EGVEAFFYEPYQGAIQGPEEFVEGMALGLKALVGGAVGGLAGAASKITGAMAKGVAAMTM 2937 Query: 3452 DKEYQQKRREELSRQPRDFGDSLARGGKGFLRGVVGGVTGIITKPVEGAKKEGAAGFFKG 3511 D++YQQKRRE +++QP F + + RGGKG + G V G+TGI+TKP++GA+K GAAGFFKG Sbjct: 2938 DEDYQQKRREAMNKQPAGFREGITRGGKGLVSGFVSGITGIVTKPIKGAQKGGAAGFFKG 2997 Query: 3512 IGKGLVGAVARPTGGIVDMASSTFQGIQRAAESTEEVSSLRPPRLIHEDGIIRPYDRQES 3571 +GKGLVGAVARPTGGI+DMASSTFQGI+RA E T EV SLRPPR +EDG+IRPY ++ Sbjct: 2998 VGKGLVGAVARPTGGIIDMASSTFQGIKRATE-TSEVESLRPPRFFNEDGVIRPYRLRDG 3056 Query: 3572 EGSDLLE 3578 G+ +L+ Sbjct: 3057 TGNQMLQ 3063 Score = 1149 bits (2971), Expect = 0.0 Identities = 616/1353 (45%), Positives = 889/1353 (65%), Gaps = 39/1353 (2%) Query: 1 MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAG 60 MV ESVV D+LNRFLGDYV +L+ SQL LGIW G VAL NLQIKENALS+LDVPFKVK G Sbjct: 1 MVFESVVVDVLNRFLGDYVVDLDTSQLSLGIWKGAVALKNLQIKENALSQLDVPFKVKVG 60 Query: 61 QIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEE 120 I L L IPWKNLY + V A LE +YLL+VP + IKYD +KEEK L + KQ+EL RIEE Sbjct: 61 HIGNLKLIIPWKNLYTQPVEAVLEEIYLLIVPSSRIKYDPLKEEKQLMEAKQQELKRIEE 120 Query: 121 ALQKAAEKDKPKEAKKDTFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLG 180 A QK ++++ K+DTF EKL TQ+IKN+QVKI+ IHI+YEDD+T+ +PLSFG++L Sbjct: 121 AKQKVVDQEQHLPEKQDTFAEKLVTQIIKNLQVKISSIHIRYEDDITNRDKPLSFGISLQ 180 Query: 181 ELSLLTANEHWTPCILNEADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILDQLKNEIL 240 LS+ T +++W PC+ +E +K++ KLIRLD+L AYWNV M Y + LD LKN I+ Sbjct: 181 NLSMQTTDQYWVPCLHDETEKLVRKLIRLDNLFAYWNVKSQMFYLSDYDNSLDDLKNGIV 240 Query: 241 TSGNIPPNYQYIFQPISASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKPQYLSMID 300 +P Y ++F+PISA+AKL MN ++ + PK++ IE+ NIAIE KPQY S+++ Sbjct: 241 NENIVPEGYDFVFRPISANAKLVMNRRSDFDFSAPKINLEIELHNIAIEFNKPQYFSIME 300 Query: 301 LLESVDYMVRNAPYRKYKPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIKKHRQ 360 LLESVD M +N PYRK+KP +PLH + R WW YAI VLEV++ MWSW +I+KHRQ Sbjct: 301 LLESVDMMAQNLPYRKFKPDVPLHHHAREWWAYAIHGVLEVNVCPRLWMWSWKHIRKHRQ 360 Query: 361 LLKSYKIAYKNKLTQSKVSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKS 420 +K YK YK KLT K E+ +++LEKTLDVFNI +ARQ A+VEV ++G K+ K+ Sbjct: 361 KVKQYKELYKKKLTSKKPPGELLVSLEELEKTLDVFNITIARQTAEVEVKKAGYKIYKEG 420 Query: 421 ADTGEKRGGWFSGLWGKKESKKKDEE-SLIPETIDDLMTPEEKDKLFTAIGYSESTHNLT 479 E GWFS LW E +++ + PET+++++TPEEK L+ AIGYSE+ + T Sbjct: 421 VKDPEDNKGWFSWLWSWSEQNTNEQQPDVQPETLEEMLTPEEKALLYEAIGYSETAVDPT 480 Query: 480 LPKQYVAHIMTLKLVSTSVTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVEAKLEHW 539 L K + A + L S S+ +REN PE++ I I T + QRPGAQA+K E K++ + Sbjct: 481 LLKTFEALKFFVHLKSMSIVLRENHQKPELVDIVIEEFSTLIVQRPGAQAIKFETKIDSF 540 Query: 540 YITGLRQQDIVPSLVASIGDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIYDAKTVN 599 +ITGL P L++S+ D SL +I FE NP D Q I++++P+E+IYDA+TVN Sbjct: 541 HITGLPDNSEKPRLLSSL-DDAMSLFQITFEINPLDETVSQRCIIEAEPLEIIYDARTVN 599 Query: 600 AVVEFFQSNKGLDLEQITSATLMKLEEIKERTATGLTHIIETRKVLDLRINLKPSYLVVP 659 ++VEFF+ K + L Q+T+ATL KLEE + +TATGL +IIET+KVLDL+INLK SY++VP Sbjct: 600 SIVEFFRPPKEVHLAQLTAATLTKLEEFRSKTATGLLYIIETQKVLDLKINLKASYIIVP 659 Query: 660 QTGFHHEKSDLLILDFGTFQLNSKDQGL---QKTTNSSLEEIMDKAYDKFDVEIKNVQLL 716 Q G S+LL+LD G ++ SK + K ++L+EIMD+AYD FD+++ +VQLL Sbjct: 660 QDGIFSPTSNLLLLDLGHLKVTSKSRSELPDVKQGEANLKEIMDRAYDSFDIQLTSVQLL 719 Query: 717 FARAEETWKKCRFQHPSTMHILQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVRISD 776 ++R + W++ R ST HIL PM ++EL+KAMV D+RM +FK+ G LPL+ +RISD Sbjct: 720 YSRVGDNWREARKLSVSTQHILVPMHFNLELSKAMVFMDVRMPKFKIYGKLPLISLRISD 779 Query: 777 QKMKDVLYLMNSIPLPQKSSAQSPERQVSS-IPIISGGTKGLLGTSLLLDTV-------- 827 +K++ ++ L+ SIP P+ P +VS+ + T LGTS + + Sbjct: 780 KKLQGIMELIESIPKPE------PVTEVSAPVKSFQIQTSTSLGTSQISQKIIPLLELPS 833 Query: 828 --ESESDDEYFDAEDGE-------PQTCKSMKGSELKKAAEVPNEELINLLLKFEIKEVI 878 E +S++E+FDA P KS++ +L+K + + + ++FE+ +V+ Sbjct: 834 VSEDDSEEEFFDAPCSPLEEPLQFPTGVKSIRTRKLQK--QDCSVNMTTFKIRFEVPKVL 891 Query: 879 LEFTKQQKE-EDTILVFNVTQLGTEATMRTFDLTVVSYLKKISLDYHEIEGSKRKPLHLI 937 +EF + E +++ V LG E +RT+DL ++LK+ L E +KP++L+ Sbjct: 892 IEFYHLVGDCELSVVEILVLGLGAEIEIRTYDLKANAFLKEFCLKCPEYLDENKKPVYLV 951 Query: 938 SSSDKPGLDLLKVEYIKADKNGPSFQTAFGKTEQTVKVAFSSLNLLLQTQALVASINYLT 997 ++ D DLL +EY+KA+KN P ++ + Q +KV FSSL++ L T+AL+ +INYL Sbjct: 952 TTLDNTMEDLLTLEYVKAEKNVPDLKSTYNNVLQLIKVNFSSLDIHLHTEALLNTINYLH 1011 Query: 998 TIIP-SDDQSISVAKEVQISTEKQQKNSTLPK-AIVSSRDSDIIDFRLFAKLNAFCVIVC 1055 I+P S+++S V+ +TE + K + K A+ S + DII ++ A+L+ + + Sbjct: 1012 NILPQSEEKSAPVS-----TTETEDKGDVIKKLALKLSTNEDIITLQILAELSCLQIFIQ 1066 Query: 1056 NEKNNIAEIKIQGLDSSLSLQSRKQSLFARLENIIVTDVDPKTVHKKAVSIMGNEVFRFN 1115 ++K NI+EIKI+GLDS + ++ + + A+L NIIV D D ++KKAV I G EVF F Sbjct: 1067 DQKCNISEIKIEGLDSEMIMRPSETEINAKLRNIIVLDSDITAIYKKAVYITGKEVFSFK 1126 Query: 1116 LDLYPDATEGDLYTDMSKVDGVLSLNVGCIQIVYLHKFLMSLLNFLNNFQTAKESLSAAT 1175 + Y DAT G YTDM+ VD ++L VGCI++V++ KFL S+L F++NFQ AK++L+ AT Sbjct: 1127 MVSYMDATAGSAYTDMNVVDIQVNLIVGCIEVVFVTKFLYSILAFIDNFQAAKQALAEAT 1186 Query: 1176 AQAAERAATSVKDLAQRSFRVSINIDLKAPVIVIPQSSISTNAVVVDLGLIRVHNQFSLV 1235 QAA AAT VK+LAQRS R++++I++KAPV+VIPQS +S N V D GLI + N F ++ Sbjct: 1187 VQAAGMAATGVKELAQRSSRMALDINIKAPVVVIPQSPVSENVFVADFGLITMTNTFHMI 1246 Query: 1236 SDEDYLNPPVIDRMDVQLTKLTLYRTVIQPGIYHPDIQLLHPINLEFLVNRNLAASWYHK 1295 ++ PPVID + ++L+++ LYR+ Y + LL P+NLE +V RNL WY + Sbjct: 1247 TESQSSPPPVIDLITIKLSEMRLYRSRFINDAYQEVLDLLLPLNLEVVVERNLCWEWYQE 1306 Query: 1296 VPVVEIKGHLDSMNVSLNQEDLNLLFRILTENL 1328 VP + L M L+QED+ +F+ L N+ Sbjct: 1307 VPCFNVNAQLKPMEFILSQEDITTIFKTLHGNI 1339 Score = 54.7 bits (130), Expect = 2e-06 Identities = 82/394 (20%), Positives = 175/394 (44%), Gaps = 57/394 (14%) Query: 1517 FSEPSSSEKESELKP------LVGESRSIAVKAVSSNISQKD-----VFD-LKITAELNA 1564 +SE +++E++ +++P L E +++ +A+ + + D F+ LK L + Sbjct: 437 WSEQNTNEQQPDVQPETLEEMLTPEEKALLYEAIGYSETAVDPTLLKTFEALKFFVHLKS 496 Query: 1565 FNVFVCD--QKCNIADIKIHGMDASISVKPKQTDVF--ARLKDIIVMNVDLQSIHKKAVS 1620 ++ + + QK + DI I I +P + ++ + + S + +S Sbjct: 497 MSIVLRENHQKPELVDIVIEEFSTLIVQRPGAQAIKFETKIDSFHITGLPDNSEKPRLLS 556 Query: 1621 ILGDEVFRFQLTLYPDATEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQ 1680 L D + FQ+T + + V + + ++I+Y + S++ F F+ Sbjct: 557 SLDDAMSLFQITFEINPLD-------ETVSQRCIIEAEPLEIIYDARTVNSIVEF---FR 606 Query: 1681 TAKEA----LSTATVQAAE----RAASSMKDLAQKSFRLLMDINLKAPVIIIPQSSV--- 1729 KE L+ AT+ E + A+ + + + L + INLKA II+PQ + Sbjct: 607 PPKEVHLAQLTAATLTKLEEFRSKTATGLLYIIETQKVLDLKINLKASYIIVPQDGIFSP 666 Query: 1730 SPNAVIADLGLIRVENK----FSLVPMEHYSLPPVIDK----MNIELTQLKLSRTIL--- 1778 + N ++ DLG ++V +K V +L ++D+ +I+LT ++L + + Sbjct: 667 TSNLLLLDLGHLKVTSKSRSELPDVKQGEANLKEIMDRAYDSFDIQLTSVQLLYSRVGDN 726 Query: 1779 ---QASLPQNDIEILKPVNMLLSIQRNLAAAWYVQIPGMEIKGKLKPMQVALSEDDLTVL 1835 L + IL P++ L + + + V++P +I GKL + + +S+ L + Sbjct: 727 WREARKLSVSTQHILVPMHFNLELSKAM-VFMDVRMPKFKIYGKLPLISLRISDKKLQGI 785 Query: 1836 MKILLENLGEASSQPSPTQSVQETVRVRKVDVSS 1869 M+++ E+ +P P V V+ ++ S+ Sbjct: 786 MELI-----ESIPKPEPVTEVSAPVKSFQIQTST 814 >gi|66346672 vacuolar protein sorting 13A isoform C [Homo sapiens] Length = 3135 Score = 1627 bits (4214), Expect = 0.0 Identities = 968/2526 (38%), Positives = 1477/2526 (58%), Gaps = 182/2526 (7%) Query: 1145 IQIVYLHKFLMSLLNFLNNFQTAKE----SLSAATAQAAE----RAATSVKDLAQRSFRV 1196 ++I+Y + + S++ F F+ KE L+AAT E + AT + + + + Sbjct: 589 LEIIYDARTVNSIVEF---FRPPKEVHLAQLTAATLTKLEEFRSKTATGLLYIIETQKVL 645 Query: 1197 SINIDLKAPVIVIPQSSI---STNAVVVDLGLIRV----HNQFSLVSDEDYLNPPVIDR- 1248 + I+LKA I++PQ I ++N +++DLG ++V ++ V + ++DR Sbjct: 646 DLKINLKASYIIVPQDGIFSPTSNLLLLDLGHLKVTSKSRSELPDVKQGEANLKEIMDRA 705 Query: 1249 ---MDVQLTKLTL--------YRTVIQPGIYHPDIQLLHPINLE------FLVNRNLAAS 1291 D+QLT + L +R + + I + NLE F+ R Sbjct: 706 YDSFDIQLTSVQLLYSRVGDNWREARKLSVSTQHILVPMHFNLELSKAMVFMDVRMPKFK 765 Query: 1292 WYHKVPVVEIK-------GHLDSMNVSLNQEDLNLL------FRILTENLCEGTEDLDKV 1338 Y K+P++ ++ G ++ + E + + F+I T ++ K+ Sbjct: 766 IYGKLPLISLRISDKKLQGIMELIESIPKPEPVTEVSAPVKSFQIQTSTSLGTSQISQKI 825 Query: 1339 KPRVQETGEIKEPLEISISQDVHDSKNT-------LTTGVEEIR---------SVDIINM 1382 P + E+ E ++ D+ + TGV+ IR SV++ Sbjct: 826 IPLL----ELPSVSEDDSEEEFFDAPCSPLEEPLQFPTGVKSIRTRKLQKQDCSVNMTTF 881 Query: 1383 LLNFEIKEVVVTLMKKSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFDFT 1442 + FE+ +V++ + E+ VL LG E +++TYD+ A A+LK+ ++C ++ Sbjct: 882 KIRFEVPKVLIEFYHLVGDCELSVVEILVLGLGAEIEIRTYDLKANAFLKEFCLKCPEYL 941 Query: 1443 DSKGEPLHIINSSNVTDEPLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLHLE 1502 D +P++++ + + T E LL + KA+ + P+ K+ +++ Q +KV+F+SLD+ LH E Sbjct: 942 DENKKPVYLVTTLDNTMEDLLTLEYVKAEKNVPDLKSTYNNVLQLIKVNFSSLDIHLHTE 1001 Query: 1503 ALLSFMDFLSSAAPFSEPSSSEKESELKPLVGESRSIAVKAVSSNISQKDVFDLKITAEL 1562 ALL+ +++L + P SE S A S +D D+ Sbjct: 1002 ALLNTINYLHNILPQSEEKS--------------------APVSTTETEDKGDV------ 1035 Query: 1563 NAFNVFVCDQKCNIADIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQSIHKKAVSIL 1622 IK G+D+ + ++P +T++ A+L++IIV++ D+ +I+KKAV I Sbjct: 1036 ----------------IKKLGLDSEMIMRPSETEINAKLRNIIVLDSDITAIYKKAVYIT 1079 Query: 1623 GDEVFRFQLTLYPDATEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQTA 1682 G EVF F++ Y DAT G AY DM+ VD +++ VGCI++V+V KF S+L F++NFQ A Sbjct: 1080 GKEVFSFKMVSYMDATAGSAYTDMNVVDIQVNLIVGCIEVVFVTKFLYSILAFIDNFQAA 1139 Query: 1683 KEALSTATVQAAERAASSMKDLAQKSFRLLMDINLKAPVIIIPQSSVSPNAVIADLGLIR 1742 K+AL+ ATVQAA AA+ +K+LAQ+S R+ +DIN+KAPV++IPQS VS N +AD GLI Sbjct: 1140 KQALAEATVQAAGMAATGVKELAQRSSRMALDINIKAPVVVIPQSPVSENVFVADFGLIT 1199 Query: 1743 VENKFSLVPMEHYSLPPVIDKMNIELTQLKLSRTILQASLPQNDIEILKPVNMLLSIQRN 1802 + N F ++ S PPVID + I+L++++L R+ Q +++L P+N+ + ++RN Sbjct: 1200 MTNTFHMITESQSSPPPVIDLITIKLSEMRLYRSRFINDAYQEVLDLLLPLNLEVVVERN 1259 Query: 1803 LAAAWYVQIPGMEIKGKLKPMQVALSEDDLTVLMKILLENLG-EASSQPSPTQSVQETVR 1861 L WY ++P + +LKPM+ LS++D+T + K L N+ E SP + + Sbjct: 1260 LCWEWYQEVPCFNVNAQLKPMEFILSQEDITTIFKTLHGNIWYEKDGSASPAVTKDQYSA 1319 Query: 1862 VRKVDVSSVPDHLKEQEDWTDSKLSMNQIV-----SLQFDFHFESLSIILYNNDINQESG 1916 V ++ H T + + ++ +L F + L+++LY+ Q S Sbjct: 1320 TSGV-TTNASHHSGGATVVTAAVVEVHSRALLVKTTLNISFKTDDLTMVLYSPGPKQASF 1378 Query: 1917 VAFHNDSFQLGELRLHLMASSGKMFKDGSMNVSVKLKTCTLDDLREGIERATSRMIDRKN 1976 + S +L E +L + S+ KM+ DGS S LK C LDD R +++AT RMI Sbjct: 1379 TDVRDPSLKLAEFKLENIISTLKMYTDGSTFSSFSLKNCILDDKRPHVKKATPRMIGLTV 1438 Query: 1977 DQDNNSSMIDISYKQDKNGSQIDAVLDKLYVCASVEFLMTVADFFIKAVPQSPENVAKET 2036 D M+DI Y++ ++G DAV ++Y+CASVEFL TVA+ F++A A ET Sbjct: 1439 GFDKKD-MMDIKYRKVRDGCVTDAVFQEMYICASVEFLQTVANVFLEAYTTG---TAVET 1494 Query: 2037 QILPRQTATGKVKIEKDDSVRPNMTLKAMITDPEVVFVASLTKADAPALTASFQCNLSLS 2096 + QT T K ++ +SV+ + +I +PE+VFVA +TK DAPAL + QC + Sbjct: 1495 SV---QTWTAKEEVPTQESVK--WEINVIIKNPEIVFVADMTKNDAPALVITTQCEICYK 1549 Query: 2097 TSKLEQMMEASVRDLKVLACPFLREKRGKNITTVLQPCSLFMEKCTWASGKQNINIMVKE 2156 + M A+++DL+V ACPFL KR ITTVLQPC LF + + Q I++ VK Sbjct: 1550 GNLENSTMTAAIKDLQVRACPFLPVKRKGKITTVLQPCDLFYQTTQKGTDPQVIDMSVKS 1609 Query: 2157 FIIKISPIILNTVLTIMAALSPKTKEDGSKDTSKEMENLWGIKSINDYNTWFLGVDTATE 2216 +K+SP+I+NT++TI +AL TKE ++T+ +LW K WFL TE Sbjct: 1610 LTLKVSPVIINTMITITSALYT-TKETIPEETASSTAHLWEKKDTKTLKMWFLEESNETE 1668 Query: 2217 ITESFKGI--EHSLIEENCGVVVESIQVTLECGLGHRTVPLLLAESKFSGNIKNWTSLMA 2274 + + +I+ N ++SI + LE G+GHRTVP+LLA+S+FSG KNW+SL+ Sbjct: 1669 KIAPTTELVPKGEMIKMN----IDSIFIVLEAGIGHRTVPMLLAKSRFSGEGKNWSSLIN 1724 Query: 2275 AVADVTLQVHYYNEIHAVWEPLIE-----RVEGKRQWNLRLDVKKNP---VQDKSLLPGD 2326 + L+VHYYNE+ VWEPL+E + E R WNL + +KK + + + Sbjct: 1725 LHCQLELEVHYYNEMFGVWEPLLEPLEIDQTEDFRPWNLGIKMKKKAKMAIVESDPEEEN 1784 Query: 2327 DFIPEPQMAIHISSGNTMNITISKSCLNVFNNLAKGFSEG-TASTFDYSLKDRAPFTVKN 2385 +PE + I S + +NIT+SK L + NNL K F+E T S+ D+ +KD APF + N Sbjct: 1785 YKVPEYKTVISFHSKDQLNITLSKCGLVMLNNLVKAFTEAATGSSADF-VKDLAPFMILN 1843 Query: 2386 AVGVPIKVKPNCNLRVMGFPEKSDIFDVDAGQNLELEYASMVPSSQGNLSILSRQESSFF 2445 ++G+ I V P+ + V+ P + + G++L ++Y + N ++ S F Sbjct: 1844 SLGLTISVSPSDSFSVLNIPMAKS-YVLKNGESLSMDYIRTKDNDHFNA--MTSLSSKLF 1900 Query: 2446 TLTIVPHGYTEVANIPVARPGRRLYNVRNPNASHSDSVLVQIDATEGNKVITLRSPLQIK 2505 + + P ++ IP+ + GRRLY VR+ + S++ QID EG+K +T+RSP+QI+ Sbjct: 1901 FILLTPVNHSTADKIPLTKVGRRLYTVRHRESGVERSIVCQIDTVEGSKKVTIRSPVQIR 1960 Query: 2506 NHFSIAFIIYKFVKNVKLLERIGIARPEEEFHVPLDSYRCQLFIQPAGILEHQYKESTTY 2565 NHFS+ +Y+ +G A PE EF++PL SYR +F++P +Q E + Sbjct: 1961 NHFSVPLSVYEGDT------LLGTASPENEFNIPLGSYRSFIFLKPEDE-NYQMCEGIDF 2013 Query: 2566 ISWKEELHRSREVRCMLQCPSVEVSFLPLIVNTVALPDELSYICTHGED-WDVAYIIHLY 2624 EE+ ++ +C S S ++N V D L+ + + ED WD+ YI+HL+ Sbjct: 2014 ----EEIIKNDGALLKKKCRSKNPSKESFLINIVPEKDNLTSLSVYSEDGWDLPYIMHLW 2069 Query: 2625 PSLTLRNLLPYSLRYLLEGTAET-HELAEGSTADVLHSRISGEIMELVLVKYQGKNWNGH 2683 P + LRNLLPY + Y +EG + L+EG +A + +++ + L L+ Y +W Sbjct: 2070 PPILLRNLLPYKIAYYIEGIENSVFTLSEGHSAQICTAQLGKARLHLKLLDYLNHDWKSE 2129 Query: 2684 FRIRDTLPEFFPVCFSS-DSTEVTTVDLSVHVRRIGSRMVLSVFSPYWLINKTTRVLQYR 2742 + I+ + V F+ E T +D++VH+ + V++ SPYW++NKT R+LQY+ Sbjct: 2130 YHIKPNQQDISFVSFTCVTEMEKTDLDIAVHMTYNTGQTVVAFHSPYWMVNKTGRMLQYK 2189 Query: 2743 SEDIHVKHPADFRDIILFSFKKKNIFTKNKVQLKISTSAWSSSFSLDTVGSYGCVKCPAN 2802 ++ IH KHP +++ +LFSF+ + F NKVQL ++ S S+ FS+DTVGS+G VKC Sbjct: 2190 ADGIHRKHPPNYKKPVLFSFQPNHFFNNNKVQLMVTDSELSNQFSIDTVGSHGAVKCKGL 2249 Query: 2803 NMEYLVGVSIKMSSFNLSRIVTLTPFCTIANKSSLELEVGEIASDGSMPTNKWNYIASSE 2862 M+Y VGV+I +SSFN++RIVT TPF I NKS + V E +D KW + + Sbjct: 2250 KMDYQVGVTIDLSSFNITRIVTFTPFYMIKNKSKYHISVAEEGND------KWLSLDLEQ 2303 Query: 2863 CLPFWPESLSGKLCVRVVGCEGSSKPFFYNRQDNGTLLSLEDLNGGILVDVNTAEHSTVI 2922 C+PFWPE S KL ++V E K ++N+Q+N LL L++ GGI+ +VN AEHSTVI Sbjct: 2304 CIPFWPEYASSKLLIQVERSEDPPKRIYFNKQENCILLRLDNELGGIIAEVNLAEHSTVI 2363 Query: 2923 TFSDYHEGSAPALIMNHTPWDILTYKQSGSPE-EMVLLPRQARLFAWADPTGTRKLTWTY 2981 TF DYH+G+A L++NHT +++ Y QS E E L P +A + WADP G+R+L W Sbjct: 2364 TFLDYHDGAATFLLINHTKNELVQYNQSSLSEIEDSLPPGKAVFYTWADPVGSRRLKWRC 2423 Query: 2982 AANVGEHDLLKDGCGQFPYDANIQ-IHWVSFLDGRQRVLLFTDDVALVSKALQAEEMEQA 3040 + GE D P D + I+ VSF +G QR++LFT+D + ++E+ E A Sbjct: 2424 RKSHGEVTQKDDM--MMPIDLGEKTIYLVSFFEGLQRIILFTEDPRVFKVTYESEKAELA 2481 Query: 3041 DYEITLSLHSLGLSLVNNESKQEVSYIGITSSGVVWEVKPKQK--WKPFSQKQIILLEQS 3098 + EI ++L +G+SLVNN +KQEV+YIGITSS VVWE KPK+K WKP S K LE+ Sbjct: 2482 EQEIAVALQDVGISLVNNYTKQEVAYIGITSSDVVWETKPKKKARWKPMSVKHTEKLERE 2541 Query: 3099 YQKHQISR--DHGWIKLDNNFEVNFDKDPMEMRL--PIRSPIKRDFLSGIQIEFKQSSHQ 3154 ++++ S + I+LD N V M++ P ++R++L +++E+ S+HQ Sbjct: 2542 FKEYTESSPSEDKVIQLDTNVPVRLTPTGHNMKILQPHVIALRRNYLPALKVEYNTSAHQ 2601 Query: 3155 RSLRARLYWLQVDNQLPGAMFPVVFHPVAPPKSIALDSEPKPFIDVSVITRFNEYSKVLQ 3214 S R ++Y +Q+ NQ+ GA+FP VF+PV PPKS+ +DS PKPF DVS++ R +S++ + Sbjct: 2602 SSFRIQIYRIQIQNQIHGAVFPFVFYPVKPPKSVTMDSAPKPFTDVSIVMRSAGHSQISR 2661 Query: 3215 FKYFMVLIQEMALKIDQGFLGAIIALFTPTTDPEAERRRTKLIQQDIDALNAELMETSMT 3274 KYF VLIQEM L++D GF+ A+ L T E +L +DI+A E S+ Sbjct: 2662 IKYFKVLIQEMDLRLDLGFIYALTDLMTEAE--VTENTEVELFHKDIEAFKEEYKTASLV 2719 Query: 3275 DMSILSFFEHFHISPVKLHLSLSLGSGGEESDKEKQE--MFAVHSVNLLLKSIGATLTDV 3332 D S +S +E+FHISP+KLHLS+SL SG EE+ KQ + VHS+NLLLKSIGATLTDV Sbjct: 2720 DQSQVSLYEYFHISPIKLHLSVSLSSGREEAKDSKQNGGLIPVHSLNLLLKSIGATLTDV 2779 Query: 3333 DDLIFKLAYYEIRYQFYKRDQLIWSVVRHYSEQFLKQMYVLVLGLDVLGNPFGLIRGLSE 3392 D++FKLA++E+ YQF+ L V+RHYS+Q +KQMYVL+LGLDVLGNPFGLIR SE Sbjct: 2780 QDVVFKLAFFELNYQFHTTSDLQSEVIRHYSKQAIKQMYVLILGLDVLGNPFGLIREFSE 2839 Query: 3393 GVEALFYEPFQGAVQGPEEFAEGLVIGVRSLFGHTVGGAAGVVSRITGSVGKGLAAITMD 3452 GVEA FYEP+QGA+QGPEEF EG+ +G+++L G VGG AG S+ITG++ KG+AA+TMD Sbjct: 2840 GVEAFFYEPYQGAIQGPEEFVEGMALGLKALVGGAVGGLAGAASKITGAMAKGVAAMTMD 2899 Query: 3453 KEYQQKRREELSRQPRDFGDSLARGGKGFLRGVVGGVTGIITKPVEGAKKEGAAGFFKGI 3512 ++YQQKRRE +++QP F + + RGGKG + G V G+TGI+TKP++GA+K GAAGFFKG+ Sbjct: 2900 EDYQQKRREAMNKQPAGFREGITRGGKGLVSGFVSGITGIVTKPIKGAQKGGAAGFFKGV 2959 Query: 3513 GKGLVGAVARPTGGIVDMASSTFQGIQRAAESTEEVSSLRPPRLIHEDGIIRPYDRQESE 3572 GKGLVGAVARPTGGI+DMASSTFQGI+RA E T EV SLRPPR +EDG+IRPY ++ Sbjct: 2960 GKGLVGAVARPTGGIIDMASSTFQGIKRATE-TSEVESLRPPRFFNEDGVIRPYRLRDGT 3018 Query: 3573 GSDLLE 3578 G+ +L+ Sbjct: 3019 GNQMLQ 3024 Score = 1108 bits (2865), Expect = 0.0 Identities = 601/1351 (44%), Positives = 863/1351 (63%), Gaps = 74/1351 (5%) Query: 1 MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAG 60 MV ESVV D+LNRFLGDYV +L+ SQL LGIW G VAL NLQIKENALS+LDVPFKVK G Sbjct: 1 MVFESVVVDVLNRFLGDYVVDLDTSQLSLGIWKGAVALKNLQIKENALSQLDVPFKVKVG 60 Query: 61 QIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEE 120 I L L IPWKNLY + V A LE +YLL+VP + IKYD +KEEK L + KQ+EL RIEE Sbjct: 61 HIGNLKLIIPWKNLYTQPVEAVLEEIYLLIVPSSRIKYDPLKEEKQLMEAKQQELKRIEE 120 Query: 121 ALQKAAEKDKPKEAKKDTFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLG 180 A QK ++++ K+DTF EKL TQ+IKN+QVKI+ IHI+YEDD+T+ +PLSFG++L Sbjct: 121 AKQKVVDQEQHLPEKQDTFAEKLVTQIIKNLQVKISSIHIRYEDDITNRDKPLSFGISLQ 180 Query: 181 ELSLLTANEHWTPCILNEADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILDQLKNEIL 240 LS+ T +++W PC+ +E +K++ KLIRLD+L AYWNV M Y + LD LKN I+ Sbjct: 181 NLSMQTTDQYWVPCLHDETEKLVRKLIRLDNLFAYWNVKSQMFYLSDYDNSLDDLKNGIV 240 Query: 241 TSGNIPPNYQYIFQPISASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKPQYLSMID 300 +P Y ++F+PISA+AKL MN ++ + PK++ IE+ NIAIE KPQY S+++ Sbjct: 241 NENIVPEGYDFVFRPISANAKLVMNRRSDFDFSAPKINLEIELHNIAIEFNKPQYFSIME 300 Query: 301 LLESVDYMVRNAPYRKYKPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIKKHRQ 360 LLESVD M +N PYRK+KP +PLH + R WW YAI VLEV++ MWSW +I+KHRQ Sbjct: 301 LLESVDMMAQNLPYRKFKPDVPLHHHAREWWAYAIHGVLEVNVCPRLWMWSWKHIRKHRQ 360 Query: 361 LLKSYKIAYKNKLTQSKVSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKS 420 +K YK YK KLT K E+ +++LEKTLDVFNI +ARQ A+VEV ++G K+ K+ Sbjct: 361 KVKQYKELYKKKLTSKKPPGELLVSLEELEKTLDVFNITIARQTAEVEVKKAGYKIYKEG 420 Query: 421 ADTGEKRGGWFSGLWGKKESKKKDEE-SLIPETIDDLMTPEEKDKLFTAIGYSESTHNLT 479 E GWFS LW E +++ + PET+++++TPEEK L+ AIGYSE+ + T Sbjct: 421 VKDPEDNKGWFSWLWSWSEQNTNEQQPDVQPETLEEMLTPEEKALLYEAIGYSETAVDPT 480 Query: 480 LPKQYVAHIMTLKLVSTSVTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVEAKLEHW 539 L K + A + L S S+ +REN PE++ I I T + QRPGAQA+K E K++ + Sbjct: 481 LLKTFEALKFFVHLKSMSIVLRENHQKPELVDIVIEEFSTLIVQRPGAQAIKFETKIDSF 540 Query: 540 YITGLRQQDIVPSLVASIGDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIYDAKTVN 599 +ITGL P L++S+ D SL +I FE NP D Q I++++P+E+IYDA+TVN Sbjct: 541 HITGLPDNSEKPRLLSSL-DDAMSLFQITFEINPLDETVSQRCIIEAEPLEIIYDARTVN 599 Query: 600 AVVEFFQSNKGLDLEQITSATLMKLEEIKERTATGLTHIIETRKVLDLRINLKPSYLVVP 659 ++VEFF+ K + L Q+T+ATL KLEE + +TATGL +IIET+KVLDL+INLK SY++VP Sbjct: 600 SIVEFFRPPKEVHLAQLTAATLTKLEEFRSKTATGLLYIIETQKVLDLKINLKASYIIVP 659 Query: 660 QTGFHHEKSDLLILDFGTFQLNSKDQGL---QKTTNSSLEEIMDKAYDKFDVEIKNVQLL 716 Q G S+LL+LD G ++ SK + K ++L+EIMD+AYD FD+++ +VQLL Sbjct: 660 QDGIFSPTSNLLLLDLGHLKVTSKSRSELPDVKQGEANLKEIMDRAYDSFDIQLTSVQLL 719 Query: 717 FARAEETWKKCRFQHPSTMHILQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVRISD 776 ++R + W++ R ST HIL PM ++EL+KAMV D+RM +FK+ G LPL+ +RISD Sbjct: 720 YSRVGDNWREARKLSVSTQHILVPMHFNLELSKAMVFMDVRMPKFKIYGKLPLISLRISD 779 Query: 777 QKMKDVLYLMNSIPLPQKSSAQSPERQVSS-IPIISGGTKGLLGTSLLLDTV-------- 827 +K++ ++ L+ SIP P+ P +VS+ + T LGTS + + Sbjct: 780 KKLQGIMELIESIPKPE------PVTEVSAPVKSFQIQTSTSLGTSQISQKIIPLLELPS 833 Query: 828 --ESESDDEYFDAEDGE-------PQTCKSMKGSELKKAAEVPNEELINLLLKFEIKEVI 878 E +S++E+FDA P KS++ +L+K + + + ++FE+ +V+ Sbjct: 834 VSEDDSEEEFFDAPCSPLEEPLQFPTGVKSIRTRKLQK--QDCSVNMTTFKIRFEVPKVL 891 Query: 879 LEFTKQQKE-EDTILVFNVTQLGTEATMRTFDLTVVSYLKKISLDYHEIEGSKRKPLHLI 937 +EF + E +++ V LG E +RT+DL ++LK+ L E +KP++L+ Sbjct: 892 IEFYHLVGDCELSVVEILVLGLGAEIEIRTYDLKANAFLKEFCLKCPEYLDENKKPVYLV 951 Query: 938 SSSDKPGLDLLKVEYIKADKNGPSFQTAFGKTEQTVKVAFSSLNLLLQTQALVASINYLT 997 ++ D DLL +EY+KA+KN P ++ + Q +KV FSSL++ L T+AL+ +INYL Sbjct: 952 TTLDNTMEDLLTLEYVKAEKNVPDLKSTYNNVLQLIKVNFSSLDIHLHTEALLNTINYLH 1011 Query: 998 TIIPSDDQSISVAKEVQISTEKQQKNSTLPKAIVSSRDSDIIDFRLFAKLNAFCVIVCNE 1057 I+P ++ K +ST + + + Sbjct: 1012 NILPQSEE-----KSAPVSTTETE-----------------------------------D 1031 Query: 1058 KNNIAEIKIQGLDSSLSLQSRKQSLFARLENIIVTDVDPKTVHKKAVSIMGNEVFRFNLD 1117 K ++ IK GLDS + ++ + + A+L NIIV D D ++KKAV I G EVF F + Sbjct: 1032 KGDV--IKKLGLDSEMIMRPSETEINAKLRNIIVLDSDITAIYKKAVYITGKEVFSFKMV 1089 Query: 1118 LYPDATEGDLYTDMSKVDGVLSLNVGCIQIVYLHKFLMSLLNFLNNFQTAKESLSAATAQ 1177 Y DAT G YTDM+ VD ++L VGCI++V++ KFL S+L F++NFQ AK++L+ AT Q Sbjct: 1090 SYMDATAGSAYTDMNVVDIQVNLIVGCIEVVFVTKFLYSILAFIDNFQAAKQALAEATVQ 1149 Query: 1178 AAERAATSVKDLAQRSFRVSINIDLKAPVIVIPQSSISTNAVVVDLGLIRVHNQFSLVSD 1237 AA AAT VK+LAQRS R++++I++KAPV+VIPQS +S N V D GLI + N F ++++ Sbjct: 1150 AAGMAATGVKELAQRSSRMALDINIKAPVVVIPQSPVSENVFVADFGLITMTNTFHMITE 1209 Query: 1238 EDYLNPPVIDRMDVQLTKLTLYRTVIQPGIYHPDIQLLHPINLEFLVNRNLAASWYHKVP 1297 PPVID + ++L+++ LYR+ Y + LL P+NLE +V RNL WY +VP Sbjct: 1210 SQSSPPPVIDLITIKLSEMRLYRSRFINDAYQEVLDLLLPLNLEVVVERNLCWEWYQEVP 1269 Query: 1298 VVEIKGHLDSMNVSLNQEDLNLLFRILTENL 1328 + L M L+QED+ +F+ L N+ Sbjct: 1270 CFNVNAQLKPMEFILSQEDITTIFKTLHGNI 1300 Score = 54.7 bits (130), Expect = 2e-06 Identities = 82/394 (20%), Positives = 175/394 (44%), Gaps = 57/394 (14%) Query: 1517 FSEPSSSEKESELKP------LVGESRSIAVKAVSSNISQKD-----VFD-LKITAELNA 1564 +SE +++E++ +++P L E +++ +A+ + + D F+ LK L + Sbjct: 437 WSEQNTNEQQPDVQPETLEEMLTPEEKALLYEAIGYSETAVDPTLLKTFEALKFFVHLKS 496 Query: 1565 FNVFVCD--QKCNIADIKIHGMDASISVKPKQTDVF--ARLKDIIVMNVDLQSIHKKAVS 1620 ++ + + QK + DI I I +P + ++ + + S + +S Sbjct: 497 MSIVLRENHQKPELVDIVIEEFSTLIVQRPGAQAIKFETKIDSFHITGLPDNSEKPRLLS 556 Query: 1621 ILGDEVFRFQLTLYPDATEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQ 1680 L D + FQ+T + + V + + ++I+Y + S++ F F+ Sbjct: 557 SLDDAMSLFQITFEINPLD-------ETVSQRCIIEAEPLEIIYDARTVNSIVEF---FR 606 Query: 1681 TAKEA----LSTATVQAAE----RAASSMKDLAQKSFRLLMDINLKAPVIIIPQSSV--- 1729 KE L+ AT+ E + A+ + + + L + INLKA II+PQ + Sbjct: 607 PPKEVHLAQLTAATLTKLEEFRSKTATGLLYIIETQKVLDLKINLKASYIIVPQDGIFSP 666 Query: 1730 SPNAVIADLGLIRVENK----FSLVPMEHYSLPPVIDK----MNIELTQLKLSRTIL--- 1778 + N ++ DLG ++V +K V +L ++D+ +I+LT ++L + + Sbjct: 667 TSNLLLLDLGHLKVTSKSRSELPDVKQGEANLKEIMDRAYDSFDIQLTSVQLLYSRVGDN 726 Query: 1779 ---QASLPQNDIEILKPVNMLLSIQRNLAAAWYVQIPGMEIKGKLKPMQVALSEDDLTVL 1835 L + IL P++ L + + + V++P +I GKL + + +S+ L + Sbjct: 727 WREARKLSVSTQHILVPMHFNLELSKAM-VFMDVRMPKFKIYGKLPLISLRISDKKLQGI 785 Query: 1836 MKILLENLGEASSQPSPTQSVQETVRVRKVDVSS 1869 M+++ E+ +P P V V+ ++ S+ Sbjct: 786 MELI-----ESIPKPEPVTEVSAPVKSFQIQTST 814 Score = 33.5 bits (75), Expect = 3.9 Identities = 61/330 (18%), Positives = 128/330 (38%), Gaps = 36/330 (10%) Query: 495 STSVTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVEAKLEHWYITGLRQQDIVPSLV 554 S V+ E ++ +++K +GL +++ RP ++ AKL + + I V Sbjct: 1021 SAPVSTTETEDKGDVIKK--LGLDSEMIMRPSET--EINAKLRNIIVLDSDITAIYKKAV 1076 Query: 555 ASIGDTTSSLLKIKFETNPEDSPADQTLIVQSQP------VEVIYDAKTVNAVVEF---F 605 G S + + S +V Q +EV++ K + +++ F F Sbjct: 1077 YITGKEVFSFKMVSYMDATAGSAYTDMNVVDIQVNLIVGCIEVVFVTKFLYSILAFIDNF 1136 Query: 606 QSNKGLDLEQITSATLMKLEEIKERTATGLTHIIETRKVLDLRINLKPSYLVVPQTGFHH 665 Q+ K E A M ATG+ + + + L IN+K +V+PQ+ Sbjct: 1137 QAAKQALAEATVQAAGM--------AATGVKELAQRSSRMALDINIKAPVVVIPQSPV-- 1186 Query: 666 EKSDLLILDFGTFQLNSKDQGLQKTTNSSLEEIMDKAYDKFDVEIKNVQLLFARAEETWK 725 ++ + DFG + + + ++ +S I D +++ ++L +R Sbjct: 1187 -SENVFVADFGLITMTNTFHMITESQSSPPPVI-----DLITIKLSEMRLYRSRF----- 1235 Query: 726 KCRFQHPSTMHILQPMDIHVELAKAMV-EKDIRMARFKVSGGLPLMHVRISDQKMKDVLY 784 + + +L P+++ V + + + E + F V+ L M +S + + + Sbjct: 1236 -INDAYQEVLDLLLPLNLEVVVERNLCWEWYQEVPCFNVNAQLKPMEFILSQEDITTIFK 1294 Query: 785 LMNSIPLPQKSSAQSPERQVSSIPIISGGT 814 ++ +K + SP SG T Sbjct: 1295 TLHGNIWYEKDGSASPAVTKDQYSATSGVT 1324 >gi|54607141 vacuolar protein sorting 13D isoform 2 [Homo sapiens] Length = 4363 Score = 234 bits (596), Expect = 2e-60 Identities = 313/1479 (21%), Positives = 604/1479 (40%), Gaps = 268/1479 (18%) Query: 2 VLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAGQ 61 +LE +VA +LN +LG YV NLN QL + + G V L+NL +K++AL EL++PF+VKAG Sbjct: 1 MLEGLVAWVLNTYLGKYVNNLNTDQLSVALLKGAVELENLPLKKDALKELELPFEVKAGF 60 Query: 62 IDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEEA 121 I K+TL+IP+ + + V ++ L+L+ P ++ KE+ ++ K+ L +EE Sbjct: 61 IGKVTLQIPFYRPHVDPWVISISSLHLIGAPEKIQDFNDEKEKLLERERKKALLQALEEK 120 Query: 122 LQKAAEKDKPKEAKKDTFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLGE 181 + ++ + E+ + + T++++N+++KI D+H+++ED VT+P P +FG+ + Sbjct: 121 WKN--DRQQKGESYWYSVTASVVTRIVENIELKIQDVHLRFEDGVTNPSHPFAFGICIKN 178 Query: 182 LSLLTANEHWTPCILNEADKIIYKLIRLD--SLSAYWNVNCSMSYQRSREQILDQLKNEI 239 +S+ A +NE + + + +LD S YW+V+C++ + ++ + + + Sbjct: 179 VSMQNA--------VNEPVQKLMRKKQLDVAEFSIYWDVDCTLLGDLPQMELQEAMARSM 230 Query: 240 LTSGNIPPNYQYIFQPISASAKLYMNPYAESELK---TPKLDCNIEIQNIAIELTKPQYL 296 + ++ Y+ +P+ ASA L N ++ L+ +P++DC+I+++ I ++L++ QY Sbjct: 231 ESR-----SHHYVLEPVFASALLKRN-CSKKPLRSRHSPRIDCDIQLETIPLKLSQLQYR 284 Query: 297 SMIDLLESVDYMVRNAPYRKYKPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIK 356 +++ L+ ++ R +R++KP + + N R WW +A+++ L IR + +W + Sbjct: 285 QIMEFLKELERKERQVKFRRWKPKVAISKNCREWWYFALNANL-YEIREQRKRCTWDFML 343 Query: 357 KHRQLLKSYKIAYKNKLTQSKVSEEIQKEIQDLEKTLDVFNIILAR---------QQAQV 407 + SY Y NKL +S + ++E+ +E+ + + R Q+ Sbjct: 344 HRARDAVSYTDKYFNKLKGGLLSTDDKEEMCRIEEEQSFEELKILRELVHDRFHKQEELA 403 Query: 408 EVIRSGQKLRKKSADTGEKRGG----------WFSGLWGKKESKK------------KDE 445 E +R Q + + GG WF G WG ++ + + Sbjct: 404 ESLREPQFDSPGACPGAPEPGGGSGMLQYLQSWFPG-WGGWYGQQTPEGNVVEGLSAEQQ 462 Query: 446 ESLIPETI-------------DDLMTPEEKDKLFTAIGYSESTHNLTL-------PKQYV 485 E IPE I + T ++D +F + +TL P+ Sbjct: 463 EQWIPEEILGTEEFFDPTADASCMNTYTKRDHVFAKLNLQLQRGTVTLLHKEQGTPQMNE 522 Query: 486 AHIMTL-----KLVSTSVTIRENKNIPEILKIQIIGL--------GTQ----VSQRPGAQ 528 + M L KL++ S+ R + +L +++ GL GT V P + Sbjct: 523 SAFMQLEFSDVKLLAESLPRRNS----SLLSVRLGGLFLRDLATEGTMFPLLVFPNPQKE 578 Query: 529 ALKVEAKLEHWYITGLRQQDIVPSLVASIGDTTSSLLKIKFETNPEDSPADQTLIVQSQP 588 +V GL+ S D + ++ +E NP S ++ L V ++P Sbjct: 579 VGRVSQSF------GLQTTSADRSDHYPAADPDGPVFEMLYERNPAHSHFERRLNVSTRP 632 Query: 589 VEVIYDAKTVNAVVEFFQSNK------GLDLE---QITSATLMKLEEIKERTATGLTH-- 637 + +IY+ + + V +FF K G E ++ A + ++K +T + Sbjct: 633 LNIIYNPQAIKKVADFFYKGKVHTSGFGYQSELELRVAEAARRQYNKLKMQTKAEIRQTL 692 Query: 638 -------IIETRKVLDLRINLKPSYLVVPQTGFHHEKSDLLILDFGTFQL-NSKDQGLQK 689 IE K +R+++ ++ P F + L+++D G L N++D +K Sbjct: 693 DRLLVGDFIEESKRWTVRLDISAPQVIFPD-DFKFKNPVLVVVDLGRMLLTNTQDNSRRK 751 Query: 690 TTNSSLEE-------------------------------------------------IMD 700 + + S E + Sbjct: 752 SRDGSASEETQFSDDEYKTPLATPPNTPPPESSSSNGEKTPPFSGVEFSEEQLQAHLMST 811 Query: 701 KAYDKFDVEIKNVQLLFARAEETWKKCRFQHPSTMHILQPMDIHVELAKAMV-EKDIRMA 759 K Y+++ + ++Q++ R ++ WK + H+++ ++H++L + ++ D + Sbjct: 812 KMYERYSLSFMDLQIMVGRVKDNWKHVQDIDVGPTHVVEKFNVHLQLERRLIYTSDPKYP 871 Query: 760 RFKVSGGLPLMHVRISDQKMKDVLYLMNSIPLPQKSSAQSPERQVSSIPIISGGTKGLLG 819 +SG LP + + I++ K + L N L ++ + Q+ +G L Sbjct: 872 GAVLSGNLPDLKIHINEDK---ISALKNCFALLTTPEMKTSDTQIKEKIFPQEEQRGSLQ 928 Query: 820 TSLLLDTVESESDDEYFDAEDGEPQTCKSMKGSELKKAAEVPNEELINLLLKFEIKEVIL 879 S++ T +++ E Q + + N I++L F Sbjct: 929 DSVMNLTQSIVLLEQHTREVLVESQLLLAEFKVNCMQLGVESNGRYISVLKVFGTN---A 985 Query: 880 EFTKQQKEEDTILVFNVTQLGTEATMRT----FDLTVVSYLKKISLDY------------ 923 F K+ + + L V L TM+T FDL + S+ K +S D Sbjct: 986 HFVKRPYDAEVSL--TVHGLLLVDTMQTYGADFDLLMASH-KNLSFDIPTGSLRDSRAQS 1042 Query: 924 --------HEIEGSKRKPLHLISSS-----DKPGLDLLKVEYIKADKNGPSFQTAFGKTE 970 H +G+ S S K L+K+EY PS T Sbjct: 1043 PVSGPNVAHLTDGATLNDRSATSVSLDKILTKEQESLIKLEYQFVSSECPSMN--LDSTL 1100 Query: 971 QTVKVAFSSLNLLLQTQALVASINYLTTIIPSDDQSISVAKEVQISTEKQQKNSTLPKAI 1030 Q + + ++L+++L + +V I +L P + +S + ++ T Sbjct: 1101 QVISLQVNNLDIILNPETIVELIGFLQKSFPKEKDDLSPQPLMTDFERSFREQGTYQSTY 1160 Query: 1031 VSSRDSDIIDFRLFAKLNAFCVIVCNEK--NNIAEIKIQGLDSSLSLQSRKQSLFARLEN 1088 + + + RL L + EK IA I G ++S+ S + L Sbjct: 1161 EQNTEVAVEIHRLNLLLLRTVGMANREKYGRKIATASIGGTKVNVSMGS-TFDMNGSLGC 1219 Query: 1089 IIVTDVDPKTVHKKAVSIMGNEVFRFNL--DL---------YPDA--TEGDLYT--DMSK 1133 + + D+ V + V +GN V N+ D+ DA TE +T + SK Sbjct: 1220 LQLMDLTQDNVKNQYVVSIGNSVGYENIISDIGYFESVFVRMEDAALTEALSFTFVERSK 1279 Query: 1134 VDGVLSLNVGCIQIVYLHKFLMSLL--------NFLNNFQTAKESLSAATAQAAERAATS 1185 + L+L + + + KFL L NF ++A ++ A + Sbjct: 1280 QECFLNLKMASLHYNHSAKFLKELTLSMDELEENFRGMLKSAATKVTTVLATKTAEYSEM 1339 Query: 1186 VK----------------------DLAQR---SFRVSINIDLKAPVIVIPQSSISTNAVV 1220 V DLA + ++ +NI++++PV+ IP+ S +V Sbjct: 1340 VSLFETPRKTREPFILEENEIYGFDLASSHLDTVKLILNINIESPVVSIPRKPGSPELLV 1399 Query: 1221 VDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQLTKLTLY 1259 LG I + N F DE DR+ V++ + LY Sbjct: 1400 GHLGQIFIQN-FVAGDDESR-----SDRLQVEIKDIKLY 1432 Score = 139 bits (350), Expect = 5e-32 Identities = 117/442 (26%), Positives = 206/442 (46%), Gaps = 46/442 (10%) Query: 3141 LSGIQIEFKQSSHQRSLRARLYWLQVDNQLPGAMFPVVFHPVAPPKSIALDSEPKPFIDV 3200 L+GI + + Q + L + +QVDNQL G P + + V P + E P + V Sbjct: 3829 LTGINVHYTQLATSHMLELSIQDVQVDNQLIGTTQPFMLY-VTPLSNENEVIETGPAVQV 3887 Query: 3201 SVITRFNEYSKVLQFKYFMVLIQEMALKIDQGFLGAIIALFTPTTDPEAERRRTKLIQQD 3260 + + ++ + +K+ M+ Q ++I++ L +++ F E+E +++ Sbjct: 3888 NAVKFPSKSALTNIYKHLMITAQRFTVQIEEKLLLKLLSFFG-YDQAESE------VEKY 3940 Query: 3261 IDALNAELMETSMTDMSILSFFEHFHISPVKLHLSLSLGSGGEESDKEKQEMFAVHSVNL 3320 + L+ + E T I +FE+ IS ++ LS+ S+K ++ A+ S Sbjct: 3941 DENLHEKTAEQGGTP--IRYYFENLKISIPQIKLSVFT------SNKLPLDLKALKS--- 3989 Query: 3321 LLKSIGATLTDVDDLIFKLAYYEIRYQFYKRDQLIWSVVRHYSEQFLKQMYVLVLGLDVL 3380 ++G L +D + L + + + ++ +I +++H+ E+ L Q ++ +D L Sbjct: 3990 ---TLGFPLIRFEDAVINLDPFTRVHPYETKEFIINDILKHFQEELLSQAARILGSVDFL 4046 Query: 3381 GNPFGLIRGLSEGVEALFYEPFQGAVQGPEEFAEGLVIGVRSLFGHTVGGAAGVVSRITG 3440 GNP GL+ +SEGV L G V G L + G + ++ G Sbjct: 4047 GNPMGLLNDVSEGVTGLIK---YGNVGG--------------LIRNVTHGVSNSAAKFAG 4089 Query: 3441 SVGKGLAAITMDKEYQQKRREELSRQPRDFGDSLARGGKGFLRGVVGGVTGIITKPVEGA 3500 ++ GL TMD +Q + RE + G+ L G G G++GG+T +IT VEG Sbjct: 4090 TLSDGLGK-TMDNRHQSE-REYIRYHAATSGEHLVAGIHGLAHGIIGGLTSVITSTVEGV 4147 Query: 3501 KKE-GAAGFFKGIGKGLVGAVARPTGGIVDMASSTFQGIQRAAEST---EEVSSLRPPR- 3555 K E G +GF G+GKGLVG V +P G +D AS T Q ++ A + + +R PR Sbjct: 4148 KTEGGVSGFISGLGKGLVGTVTKPVAGALDFASETAQAVRDTATLSGPRTQAQRVRKPRC 4207 Query: 3556 LIHEDGIIRPYDRQESEGSDLL 3577 G++ Y ++EG + L Sbjct: 4208 CTGPQGLLPRYSESQAEGQEQL 4229 Score = 84.3 bits (207), Expect = 2e-15 Identities = 65/289 (22%), Positives = 140/289 (48%), Gaps = 17/289 (5%) Query: 947 LLKVEYIKADKNGPSFQTAFGKTEQTVKVAFSSLNLLLQTQALVASINYLTTIIPSDDQS 1006 L+ + DK P F +++ + +++ V F+ L++L+ Q V +++ +D+ + Sbjct: 1784 LVHINIFLVDKKHPEFSSSYNRVNRSIDVDFNCLDVLITLQTWVVILDFFGIGSTADNHA 1843 Query: 1007 ISVAKEVQISTEKQQKNSTLPKAIVSSRDSDIIDFRLFAKLNAFCVIVCNEKNNIAEIKI 1066 + + E + K + P A + S D ++ +L K+++ +++ + +A+ + Sbjct: 1844 MRLPPEGILHNVKLE-----PHASMESGLQDPVNTKLDLKVHSLSLVLNKTTSELAKANV 1898 Query: 1067 QGLDSSLSLQSRKQSLFARLENIIVTDVDPK-TVHKKAVSIMGNEVFRFNLDLY--PDAT 1123 L + L + +L + ++ ++D+ +++ + G E F Y PD Sbjct: 1899 SKLVAHLEMIEGDLALQGSIGSLSLSDLTCHGEFYRERFTTSGEEALIFQTFKYGRPDPL 1958 Query: 1124 EGDLYTDMSKVDGVLSLNVGCIQIVYLHKFLMSLLNFLNNFQTAKESLSAATAQAAERAA 1183 + D +SL + +Q V+ +F ++ F+ +F ++ L Q A Sbjct: 1959 L------RREHDIRVSLRMASVQYVHTQRFQAEVVAFIQHFTQLQDVLGR---QRAAIEG 2009 Query: 1184 TSVKDLAQRSFRVSINIDLKAPVIVIPQSSISTNAVVVDLGLIRVHNQF 1232 +V+D AQR RV ++I+ APV++IP+SS S N +V +LG ++V N+F Sbjct: 2010 QTVRDQAQRCSRVLLDIEAGAPVLLIPESSRSNNLIVANLGKLKVKNKF 2058 Score = 82.8 bits (203), Expect = 6e-15 Identities = 66/305 (21%), Positives = 147/305 (48%), Gaps = 20/305 (6%) Query: 1447 EPLHIINSSNVTDEPLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLHLEALLS 1506 EP ++ S D+ L+ + + D PEF + ++ + + V F LD+++ L+ + Sbjct: 1770 EPKILVGKSKF-DDSLVHINIFLVDKKHPEFSSSYNRVNRSIDVDFNCLDVLITLQTWVV 1828 Query: 1507 FMDFLSSAAPFSEPSSSEKESELKPLVGESRSIAVKAVSSNISQ-KDVFDLKITAELNAF 1565 +DF F S+++ + P G ++ ++ +S S +D + K+ ++++ Sbjct: 1829 ILDF------FGIGSTADNHAMRLPPEGILHNVKLEPHASMESGLQDPVNTKLDLKVHSL 1882 Query: 1566 NVFVCDQKCNIADIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQS-IHKKAVSILGD 1624 ++ + +A + + A + + + + + + ++ +++ + G+ Sbjct: 1883 SLVLNKTTSELAKANVSKLVAHLEMIEGDLALQGSIGSLSLSDLTCHGEFYRERFTTSGE 1942 Query: 1625 EVFRFQLTLY--PDATEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQTA 1682 E FQ Y PD + D ++S ++ +Q V+ +F ++ F+ +F Sbjct: 1943 EALIFQTFKYGRPDPLLRREH------DIRVSLRMASVQYVHTQRFQAEVVAFIQHFTQL 1996 Query: 1683 KEALSTATVQAAERAASSMKDLAQKSFRLLMDINLKAPVIIIPQSSVSPNAVIADLGLIR 1742 ++ L Q A +++D AQ+ R+L+DI APV++IP+SS S N ++A+LG ++ Sbjct: 1997 QDVLGR---QRAAIEGQTVRDQAQRCSRVLLDIEAGAPVLLIPESSRSNNLIVANLGKLK 2053 Query: 1743 VENKF 1747 V+NKF Sbjct: 2054 VKNKF 2058 Score = 53.9 bits (128), Expect = 3e-06 Identities = 96/441 (21%), Positives = 173/441 (39%), Gaps = 70/441 (15%) Query: 2619 YIIHLYPSLTLRNLLPYSLRYLLEGTAETHELAEGSTADVLHSRISGEIMEL-------- 2670 + I+L P++ + NLLP L + ++G L G A LH+ + + +EL Sbjct: 3151 HTIYLLPTVVICNLLPCELDFYVKGMPINGTLKPGKEA-ALHTADTSQNIELGVSLENFP 3209 Query: 2671 ----VLVKYQGKNWNGHFRIRDTLPEFFPVCFSSDSTEVTTVDLSVHVRRIGSRMVLSVF 2726 +L+ +N+ R+ D + + + + R GS + + Sbjct: 3210 LCKELLIPPGTQNYMVRMRLYDV------------NRRQLNLTIRIVCRAEGSLKIF-IS 3256 Query: 2727 SPYWLINKTTRVLQYRSEDIHVKHPADFRD--------IILFSFKKKNIFTKNKVQLKIS 2778 +PYWLINKT L +R ++ F + +LF + K N ++I Sbjct: 3257 APYWLINKTGLPLIFRQDNAKTDAAGQFEEHELARSLSPLLFCYADKE--QPNLCTMRIG 3314 Query: 2779 TS-------AWSSSFSLDTVGSYGCVKCPAN----NMEYLVGVSIK--MSSFNLSRIVTL 2825 W FSLD +K + Y +G+ +K + + +V Sbjct: 3315 RGIHPEGMPGWCQGFSLDGGSGVRALKVIQQGNRPGLIYNIGIDVKKGRGRYIDTCMVIF 3374 Query: 2826 TPFCTIANKSSLELEVGEIA-SDGSMPTNKWNYIAS---SECLPFWPES-LSGKLCVR-- 2878 P + NKSS +L + + G N YI++ S + WP + LCVR Sbjct: 3375 APRYLLDNKSSHKLAFAQREFARGQGTANPEGYISTLPGSSVVFHWPRNDYDQLLCVRLM 3434 Query: 2879 -VVGCEGSSKPFFYNRQDNGTLLSLEDLNGG---ILVDVNTAEHSTVITFSDYHEGSAPA 2934 V C S F ++N +++ D G + V++ + I+FSD + P Sbjct: 3435 DVPNCIWSGG--FEVNKNNSFHINMRDTLGKCFFLRVEITLRGATYRISFSDTDQLPPPF 3492 Query: 2935 LIMNHTPWDILTYKQSGSPEEMV---LLPRQARLFAWADPTGTRKLTWTYAANVGEHDLL 2991 I N + ++ + Q G E + + P + +AW +PT +T T G ++ Sbjct: 3493 RIDNFSKVPVV-FTQHGVAEPRLRTEVKPMTSLDYAWDEPTLPPFITLT-VKGAGSSEI- 3549 Query: 2992 KDGCGQFPYDANIQIHWVSFL 3012 C + N Q+++ +F+ Sbjct: 3550 --NCNMNDFQDNRQLYYENFI 3568 Score = 52.0 bits (123), Expect = 1e-05 Identities = 122/611 (19%), Positives = 236/611 (38%), Gaps = 138/611 (22%) Query: 1274 LLHPINLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLNQEDLNLL---FRILT--ENL 1328 ++ N+ + R L + K P + G+L + + +N++ ++ L F +LT E Sbjct: 848 VVEKFNVHLQLERRLIYTSDPKYPGAVLSGNLPDLKIHINEDKISALKNCFALLTTPEMK 907 Query: 1329 CEGTEDLDKVKPRVQETGEIKEPLEISISQDVHDSKNTLTTGVEEIRSVDIINMLLNFEI 1388 T+ +K+ P+ ++ G S+ V + ++ + R V + + LL E Sbjct: 908 TSDTQIKEKIFPQEEQRG--------SLQDSVMNLTQSIVLLEQHTREVLVESQLLLAEF 959 Query: 1389 KEVVVTLMKKSEKKGRPLHELNVLQLGMEAKVKTYD----MTAKAYLKKISMQCF--DFT 1442 K V + E GR + L V + YD +T L +MQ + DF Sbjct: 960 K--VNCMQLGVESNGRYISVLKVFGTNAHFVKRPYDAEVSLTVHGLLLVDTMQTYGADFD 1017 Query: 1443 -------------------DSKGE-PLHIINSSNVTD----------------------E 1460 DS+ + P+ N +++TD E Sbjct: 1018 LLMASHKNLSFDIPTGSLRDSRAQSPVSGPNVAHLTDGATLNDRSATSVSLDKILTKEQE 1077 Query: 1461 PLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLHLEALLSFMDFLSSAAPFSEP 1520 L+K+ S+ P DST Q + + +LD++L+ E ++ + FL + P + Sbjct: 1078 SLIKLEYQFVSSECPSMNL--DSTLQVISLQVNNLDIILNPETIVELIGFLQKSFPKEKD 1135 Query: 1521 SSSEKESELKPLVGE-SRSIAVKAVSSNISQKDVFDLKITAELNAFNVFVC--------- 1570 S + PL+ + RS + + +++ ++ E++ N+ + Sbjct: 1136 DLSPQ-----PLMTDFERSFREQGTYQSTYEQNT---EVAVEIHRLNLLLLRTVGMANRE 1187 Query: 1571 DQKCNIADIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQSIHKKAVSILGDEV---- 1626 IA I G ++S+ D+ L + +M++ ++ + V +G+ V Sbjct: 1188 KYGRKIATASIGGTKVNVSMG-STFDMNGSLGCLQLMDLTQDNVKNQYVVSIGNSVGYEN 1246 Query: 1627 -------FRFQLTLYPDATEGEA----YADMSKVDGKLSFKVGCIQIVYVHKFF----MS 1671 F DA EA + + SK + L+ K+ + + KF +S Sbjct: 1247 IISDIGYFESVFVRMEDAALTEALSFTFVERSKQECFLNLKMASLHYNHSAKFLKELTLS 1306 Query: 1672 LLNFLNNFQTAKEALST--ATVQAAERAASSMK------------------------DLA 1705 + NF+ ++ +T TV A + A S DLA Sbjct: 1307 MDELEENFRGMLKSAATKVTTVLATKTAEYSEMVSLFETPRKTREPFILEENEIYGFDLA 1366 Query: 1706 QK---SFRLLMDINLKAPVIIIPQSSVSPNAVIADLGLIRVENKFSLVPMEHYSLPPVID 1762 + +L+++IN+++PV+ IP+ SP ++ LG I ++N F E S D Sbjct: 1367 SSHLDTVKLILNINIESPVVSIPRKPGSPELLVGHLGQIFIQN-FVAGDDESRS-----D 1420 Query: 1763 KMNIELTQLKL 1773 ++ +E+ +KL Sbjct: 1421 RLQVEIKDIKL 1431 Score = 39.7 bits (91), Expect = 0.054 Identities = 86/375 (22%), Positives = 148/375 (39%), Gaps = 50/375 (13%) Query: 1274 LLHPINLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLNQEDLNLLFRILTENLCEGTE 1333 L P L+ V RNL H VP + I G+L S++ SL+ L+ +L NL E E Sbjct: 2201 LTEPCRLKLQVERNLDKEISHTVPDISIHGNLSSVHCSLDLYKYKLIRGLLENNLGEPIE 2260 Query: 1334 DLDKVKPRVQETGEIKEP-LEISISQDVHDSKNTLTTGVEEIRSVDIINMLLNF---EIK 1389 + ++P ++++P + +S +V+ L +D++N+ L + K Sbjct: 2261 EF--MRPY-----DLQDPRIHTVLSGEVYTCMCFL---------IDMVNVSLELKDPKRK 2304 Query: 1390 EVVVTLMKKSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFD--FTDSKGE 1447 E +L + KK + L+E + T L SM FD + K Sbjct: 2305 EGAGSLARFDFKKCKLLYE------------SFSNQTKSINLVSHSMMAFDTRYAGQKTS 2352 Query: 1448 PLHIINSSNVTDEPLLKMLLTKADSD-GPEFKTIHDSTKQRLKVSFASLDLVLHLEALLS 1506 P + N + +P T+ F++ DS+ V +L + L + LL Sbjct: 2353 P-GMTNVFSCIFQPAKNSSTTQGSIQIELHFRSTKDSS--CFTVVLNNLRVFLIFDWLLL 2409 Query: 1507 FMDFLSSAAPF--------SEPSSSEKESELKPLVGESRSIAVKAVSSNISQKDVFDLKI 1558 DFL + + S +S ES + P +S + K S +S + ++K+ Sbjct: 2410 VHDFLHTPSDIKKQNHVTPSRHRNSSSESAIVPKTVKS-GVVTKRSSLPVSNERHLEVKV 2468 Query: 1559 TAELNAFNVFVCDQKCNIADIKIHGMDASISVKPKQTD--VFARLKDIIVMNVDLQSIHK 1616 F V + D C + I ++ KP+ D L I V + L + H Sbjct: 2469 NVTGTEF-VVIEDVSCFDTNAIILKGTTVLTYKPRFVDRPFSGSLFGIEVFSCRLGNEHD 2527 Query: 1617 KAVSILGDEVFRFQL 1631 A+SI+ + +L Sbjct: 2528 TALSIVDPVQIQMEL 2542 >gi|54607139 vacuolar protein sorting 13D isoform 1 [Homo sapiens] Length = 4388 Score = 234 bits (596), Expect = 2e-60 Identities = 313/1479 (21%), Positives = 604/1479 (40%), Gaps = 268/1479 (18%) Query: 2 VLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAGQ 61 +LE +VA +LN +LG YV NLN QL + + G V L+NL +K++AL EL++PF+VKAG Sbjct: 1 MLEGLVAWVLNTYLGKYVNNLNTDQLSVALLKGAVELENLPLKKDALKELELPFEVKAGF 60 Query: 62 IDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEEA 121 I K+TL+IP+ + + V ++ L+L+ P ++ KE+ ++ K+ L +EE Sbjct: 61 IGKVTLQIPFYRPHVDPWVISISSLHLIGAPEKIQDFNDEKEKLLERERKKALLQALEEK 120 Query: 122 LQKAAEKDKPKEAKKDTFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLGE 181 + ++ + E+ + + T++++N+++KI D+H+++ED VT+P P +FG+ + Sbjct: 121 WKN--DRQQKGESYWYSVTASVVTRIVENIELKIQDVHLRFEDGVTNPSHPFAFGICIKN 178 Query: 182 LSLLTANEHWTPCILNEADKIIYKLIRLD--SLSAYWNVNCSMSYQRSREQILDQLKNEI 239 +S+ A +NE + + + +LD S YW+V+C++ + ++ + + + Sbjct: 179 VSMQNA--------VNEPVQKLMRKKQLDVAEFSIYWDVDCTLLGDLPQMELQEAMARSM 230 Query: 240 LTSGNIPPNYQYIFQPISASAKLYMNPYAESELK---TPKLDCNIEIQNIAIELTKPQYL 296 + ++ Y+ +P+ ASA L N ++ L+ +P++DC+I+++ I ++L++ QY Sbjct: 231 ESR-----SHHYVLEPVFASALLKRN-CSKKPLRSRHSPRIDCDIQLETIPLKLSQLQYR 284 Query: 297 SMIDLLESVDYMVRNAPYRKYKPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIK 356 +++ L+ ++ R +R++KP + + N R WW +A+++ L IR + +W + Sbjct: 285 QIMEFLKELERKERQVKFRRWKPKVAISKNCREWWYFALNANL-YEIREQRKRCTWDFML 343 Query: 357 KHRQLLKSYKIAYKNKLTQSKVSEEIQKEIQDLEKTLDVFNIILAR---------QQAQV 407 + SY Y NKL +S + ++E+ +E+ + + R Q+ Sbjct: 344 HRARDAVSYTDKYFNKLKGGLLSTDDKEEMCRIEEEQSFEELKILRELVHDRFHKQEELA 403 Query: 408 EVIRSGQKLRKKSADTGEKRGG----------WFSGLWGKKESKK------------KDE 445 E +R Q + + GG WF G WG ++ + + Sbjct: 404 ESLREPQFDSPGACPGAPEPGGGSGMLQYLQSWFPG-WGGWYGQQTPEGNVVEGLSAEQQ 462 Query: 446 ESLIPETI-------------DDLMTPEEKDKLFTAIGYSESTHNLTL-------PKQYV 485 E IPE I + T ++D +F + +TL P+ Sbjct: 463 EQWIPEEILGTEEFFDPTADASCMNTYTKRDHVFAKLNLQLQRGTVTLLHKEQGTPQMNE 522 Query: 486 AHIMTL-----KLVSTSVTIRENKNIPEILKIQIIGL--------GTQ----VSQRPGAQ 528 + M L KL++ S+ R + +L +++ GL GT V P + Sbjct: 523 SAFMQLEFSDVKLLAESLPRRNS----SLLSVRLGGLFLRDLATEGTMFPLLVFPNPQKE 578 Query: 529 ALKVEAKLEHWYITGLRQQDIVPSLVASIGDTTSSLLKIKFETNPEDSPADQTLIVQSQP 588 +V GL+ S D + ++ +E NP S ++ L V ++P Sbjct: 579 VGRVSQSF------GLQTTSADRSDHYPAADPDGPVFEMLYERNPAHSHFERRLNVSTRP 632 Query: 589 VEVIYDAKTVNAVVEFFQSNK------GLDLE---QITSATLMKLEEIKERTATGLTH-- 637 + +IY+ + + V +FF K G E ++ A + ++K +T + Sbjct: 633 LNIIYNPQAIKKVADFFYKGKVHTSGFGYQSELELRVAEAARRQYNKLKMQTKAEIRQTL 692 Query: 638 -------IIETRKVLDLRINLKPSYLVVPQTGFHHEKSDLLILDFGTFQL-NSKDQGLQK 689 IE K +R+++ ++ P F + L+++D G L N++D +K Sbjct: 693 DRLLVGDFIEESKRWTVRLDISAPQVIFPD-DFKFKNPVLVVVDLGRMLLTNTQDNSRRK 751 Query: 690 TTNSSLEE-------------------------------------------------IMD 700 + + S E + Sbjct: 752 SRDGSASEETQFSDDEYKTPLATPPNTPPPESSSSNGEKTPPFSGVEFSEEQLQAHLMST 811 Query: 701 KAYDKFDVEIKNVQLLFARAEETWKKCRFQHPSTMHILQPMDIHVELAKAMV-EKDIRMA 759 K Y+++ + ++Q++ R ++ WK + H+++ ++H++L + ++ D + Sbjct: 812 KMYERYSLSFMDLQIMVGRVKDNWKHVQDIDVGPTHVVEKFNVHLQLERRLIYTSDPKYP 871 Query: 760 RFKVSGGLPLMHVRISDQKMKDVLYLMNSIPLPQKSSAQSPERQVSSIPIISGGTKGLLG 819 +SG LP + + I++ K + L N L ++ + Q+ +G L Sbjct: 872 GAVLSGNLPDLKIHINEDK---ISALKNCFALLTTPEMKTSDTQIKEKIFPQEEQRGSLQ 928 Query: 820 TSLLLDTVESESDDEYFDAEDGEPQTCKSMKGSELKKAAEVPNEELINLLLKFEIKEVIL 879 S++ T +++ E Q + + N I++L F Sbjct: 929 DSVMNLTQSIVLLEQHTREVLVESQLLLAEFKVNCMQLGVESNGRYISVLKVFGTN---A 985 Query: 880 EFTKQQKEEDTILVFNVTQLGTEATMRT----FDLTVVSYLKKISLDY------------ 923 F K+ + + L V L TM+T FDL + S+ K +S D Sbjct: 986 HFVKRPYDAEVSL--TVHGLLLVDTMQTYGADFDLLMASH-KNLSFDIPTGSLRDSRAQS 1042 Query: 924 --------HEIEGSKRKPLHLISSS-----DKPGLDLLKVEYIKADKNGPSFQTAFGKTE 970 H +G+ S S K L+K+EY PS T Sbjct: 1043 PVSGPNVAHLTDGATLNDRSATSVSLDKILTKEQESLIKLEYQFVSSECPSMN--LDSTL 1100 Query: 971 QTVKVAFSSLNLLLQTQALVASINYLTTIIPSDDQSISVAKEVQISTEKQQKNSTLPKAI 1030 Q + + ++L+++L + +V I +L P + +S + ++ T Sbjct: 1101 QVISLQVNNLDIILNPETIVELIGFLQKSFPKEKDDLSPQPLMTDFERSFREQGTYQSTY 1160 Query: 1031 VSSRDSDIIDFRLFAKLNAFCVIVCNEK--NNIAEIKIQGLDSSLSLQSRKQSLFARLEN 1088 + + + RL L + EK IA I G ++S+ S + L Sbjct: 1161 EQNTEVAVEIHRLNLLLLRTVGMANREKYGRKIATASIGGTKVNVSMGS-TFDMNGSLGC 1219 Query: 1089 IIVTDVDPKTVHKKAVSIMGNEVFRFNL--DL---------YPDA--TEGDLYT--DMSK 1133 + + D+ V + V +GN V N+ D+ DA TE +T + SK Sbjct: 1220 LQLMDLTQDNVKNQYVVSIGNSVGYENIISDIGYFESVFVRMEDAALTEALSFTFVERSK 1279 Query: 1134 VDGVLSLNVGCIQIVYLHKFLMSLL--------NFLNNFQTAKESLSAATAQAAERAATS 1185 + L+L + + + KFL L NF ++A ++ A + Sbjct: 1280 QECFLNLKMASLHYNHSAKFLKELTLSMDELEENFRGMLKSAATKVTTVLATKTAEYSEM 1339 Query: 1186 VK----------------------DLAQR---SFRVSINIDLKAPVIVIPQSSISTNAVV 1220 V DLA + ++ +NI++++PV+ IP+ S +V Sbjct: 1340 VSLFETPRKTREPFILEENEIYGFDLASSHLDTVKLILNINIESPVVSIPRKPGSPELLV 1399 Query: 1221 VDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQLTKLTLY 1259 LG I + N F DE DR+ V++ + LY Sbjct: 1400 GHLGQIFIQN-FVAGDDESR-----SDRLQVEIKDIKLY 1432 Score = 139 bits (350), Expect = 5e-32 Identities = 117/442 (26%), Positives = 206/442 (46%), Gaps = 46/442 (10%) Query: 3141 LSGIQIEFKQSSHQRSLRARLYWLQVDNQLPGAMFPVVFHPVAPPKSIALDSEPKPFIDV 3200 L+GI + + Q + L + +QVDNQL G P + + V P + E P + V Sbjct: 3854 LTGINVHYTQLATSHMLELSIQDVQVDNQLIGTTQPFMLY-VTPLSNENEVIETGPAVQV 3912 Query: 3201 SVITRFNEYSKVLQFKYFMVLIQEMALKIDQGFLGAIIALFTPTTDPEAERRRTKLIQQD 3260 + + ++ + +K+ M+ Q ++I++ L +++ F E+E +++ Sbjct: 3913 NAVKFPSKSALTNIYKHLMITAQRFTVQIEEKLLLKLLSFFG-YDQAESE------VEKY 3965 Query: 3261 IDALNAELMETSMTDMSILSFFEHFHISPVKLHLSLSLGSGGEESDKEKQEMFAVHSVNL 3320 + L+ + E T I +FE+ IS ++ LS+ S+K ++ A+ S Sbjct: 3966 DENLHEKTAEQGGTP--IRYYFENLKISIPQIKLSVFT------SNKLPLDLKALKS--- 4014 Query: 3321 LLKSIGATLTDVDDLIFKLAYYEIRYQFYKRDQLIWSVVRHYSEQFLKQMYVLVLGLDVL 3380 ++G L +D + L + + + ++ +I +++H+ E+ L Q ++ +D L Sbjct: 4015 ---TLGFPLIRFEDAVINLDPFTRVHPYETKEFIINDILKHFQEELLSQAARILGSVDFL 4071 Query: 3381 GNPFGLIRGLSEGVEALFYEPFQGAVQGPEEFAEGLVIGVRSLFGHTVGGAAGVVSRITG 3440 GNP GL+ +SEGV L G V G L + G + ++ G Sbjct: 4072 GNPMGLLNDVSEGVTGLIK---YGNVGG--------------LIRNVTHGVSNSAAKFAG 4114 Query: 3441 SVGKGLAAITMDKEYQQKRREELSRQPRDFGDSLARGGKGFLRGVVGGVTGIITKPVEGA 3500 ++ GL TMD +Q + RE + G+ L G G G++GG+T +IT VEG Sbjct: 4115 TLSDGLGK-TMDNRHQSE-REYIRYHAATSGEHLVAGIHGLAHGIIGGLTSVITSTVEGV 4172 Query: 3501 KKE-GAAGFFKGIGKGLVGAVARPTGGIVDMASSTFQGIQRAAEST---EEVSSLRPPR- 3555 K E G +GF G+GKGLVG V +P G +D AS T Q ++ A + + +R PR Sbjct: 4173 KTEGGVSGFISGLGKGLVGTVTKPVAGALDFASETAQAVRDTATLSGPRTQAQRVRKPRC 4232 Query: 3556 LIHEDGIIRPYDRQESEGSDLL 3577 G++ Y ++EG + L Sbjct: 4233 CTGPQGLLPRYSESQAEGQEQL 4254 Score = 84.3 bits (207), Expect = 2e-15 Identities = 65/289 (22%), Positives = 140/289 (48%), Gaps = 17/289 (5%) Query: 947 LLKVEYIKADKNGPSFQTAFGKTEQTVKVAFSSLNLLLQTQALVASINYLTTIIPSDDQS 1006 L+ + DK P F +++ + +++ V F+ L++L+ Q V +++ +D+ + Sbjct: 1784 LVHINIFLVDKKHPEFSSSYNRVNRSIDVDFNCLDVLITLQTWVVILDFFGIGSTADNHA 1843 Query: 1007 ISVAKEVQISTEKQQKNSTLPKAIVSSRDSDIIDFRLFAKLNAFCVIVCNEKNNIAEIKI 1066 + + E + K + P A + S D ++ +L K+++ +++ + +A+ + Sbjct: 1844 MRLPPEGILHNVKLE-----PHASMESGLQDPVNTKLDLKVHSLSLVLNKTTSELAKANV 1898 Query: 1067 QGLDSSLSLQSRKQSLFARLENIIVTDVDPK-TVHKKAVSIMGNEVFRFNLDLY--PDAT 1123 L + L + +L + ++ ++D+ +++ + G E F Y PD Sbjct: 1899 SKLVAHLEMIEGDLALQGSIGSLSLSDLTCHGEFYRERFTTSGEEALIFQTFKYGRPDPL 1958 Query: 1124 EGDLYTDMSKVDGVLSLNVGCIQIVYLHKFLMSLLNFLNNFQTAKESLSAATAQAAERAA 1183 + D +SL + +Q V+ +F ++ F+ +F ++ L Q A Sbjct: 1959 L------RREHDIRVSLRMASVQYVHTQRFQAEVVAFIQHFTQLQDVLGR---QRAAIEG 2009 Query: 1184 TSVKDLAQRSFRVSINIDLKAPVIVIPQSSISTNAVVVDLGLIRVHNQF 1232 +V+D AQR RV ++I+ APV++IP+SS S N +V +LG ++V N+F Sbjct: 2010 QTVRDQAQRCSRVLLDIEAGAPVLLIPESSRSNNLIVANLGKLKVKNKF 2058 Score = 82.8 bits (203), Expect = 6e-15 Identities = 66/305 (21%), Positives = 147/305 (48%), Gaps = 20/305 (6%) Query: 1447 EPLHIINSSNVTDEPLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLHLEALLS 1506 EP ++ S D+ L+ + + D PEF + ++ + + V F LD+++ L+ + Sbjct: 1770 EPKILVGKSKF-DDSLVHINIFLVDKKHPEFSSSYNRVNRSIDVDFNCLDVLITLQTWVV 1828 Query: 1507 FMDFLSSAAPFSEPSSSEKESELKPLVGESRSIAVKAVSSNISQ-KDVFDLKITAELNAF 1565 +DF F S+++ + P G ++ ++ +S S +D + K+ ++++ Sbjct: 1829 ILDF------FGIGSTADNHAMRLPPEGILHNVKLEPHASMESGLQDPVNTKLDLKVHSL 1882 Query: 1566 NVFVCDQKCNIADIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQS-IHKKAVSILGD 1624 ++ + +A + + A + + + + + + ++ +++ + G+ Sbjct: 1883 SLVLNKTTSELAKANVSKLVAHLEMIEGDLALQGSIGSLSLSDLTCHGEFYRERFTTSGE 1942 Query: 1625 EVFRFQLTLY--PDATEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQTA 1682 E FQ Y PD + D ++S ++ +Q V+ +F ++ F+ +F Sbjct: 1943 EALIFQTFKYGRPDPLLRREH------DIRVSLRMASVQYVHTQRFQAEVVAFIQHFTQL 1996 Query: 1683 KEALSTATVQAAERAASSMKDLAQKSFRLLMDINLKAPVIIIPQSSVSPNAVIADLGLIR 1742 ++ L Q A +++D AQ+ R+L+DI APV++IP+SS S N ++A+LG ++ Sbjct: 1997 QDVLGR---QRAAIEGQTVRDQAQRCSRVLLDIEAGAPVLLIPESSRSNNLIVANLGKLK 2053 Query: 1743 VENKF 1747 V+NKF Sbjct: 2054 VKNKF 2058 Score = 53.9 bits (128), Expect = 3e-06 Identities = 96/441 (21%), Positives = 173/441 (39%), Gaps = 70/441 (15%) Query: 2619 YIIHLYPSLTLRNLLPYSLRYLLEGTAETHELAEGSTADVLHSRISGEIMEL-------- 2670 + I+L P++ + NLLP L + ++G L G A LH+ + + +EL Sbjct: 3176 HTIYLLPTVVICNLLPCELDFYVKGMPINGTLKPGKEA-ALHTADTSQNIELGVSLENFP 3234 Query: 2671 ----VLVKYQGKNWNGHFRIRDTLPEFFPVCFSSDSTEVTTVDLSVHVRRIGSRMVLSVF 2726 +L+ +N+ R+ D + + + + R GS + + Sbjct: 3235 LCKELLIPPGTQNYMVRMRLYDV------------NRRQLNLTIRIVCRAEGSLKIF-IS 3281 Query: 2727 SPYWLINKTTRVLQYRSEDIHVKHPADFRD--------IILFSFKKKNIFTKNKVQLKIS 2778 +PYWLINKT L +R ++ F + +LF + K N ++I Sbjct: 3282 APYWLINKTGLPLIFRQDNAKTDAAGQFEEHELARSLSPLLFCYADKE--QPNLCTMRIG 3339 Query: 2779 TS-------AWSSSFSLDTVGSYGCVKCPAN----NMEYLVGVSIK--MSSFNLSRIVTL 2825 W FSLD +K + Y +G+ +K + + +V Sbjct: 3340 RGIHPEGMPGWCQGFSLDGGSGVRALKVIQQGNRPGLIYNIGIDVKKGRGRYIDTCMVIF 3399 Query: 2826 TPFCTIANKSSLELEVGEIA-SDGSMPTNKWNYIAS---SECLPFWPES-LSGKLCVR-- 2878 P + NKSS +L + + G N YI++ S + WP + LCVR Sbjct: 3400 APRYLLDNKSSHKLAFAQREFARGQGTANPEGYISTLPGSSVVFHWPRNDYDQLLCVRLM 3459 Query: 2879 -VVGCEGSSKPFFYNRQDNGTLLSLEDLNGG---ILVDVNTAEHSTVITFSDYHEGSAPA 2934 V C S F ++N +++ D G + V++ + I+FSD + P Sbjct: 3460 DVPNCIWSGG--FEVNKNNSFHINMRDTLGKCFFLRVEITLRGATYRISFSDTDQLPPPF 3517 Query: 2935 LIMNHTPWDILTYKQSGSPEEMV---LLPRQARLFAWADPTGTRKLTWTYAANVGEHDLL 2991 I N + ++ + Q G E + + P + +AW +PT +T T G ++ Sbjct: 3518 RIDNFSKVPVV-FTQHGVAEPRLRTEVKPMTSLDYAWDEPTLPPFITLT-VKGAGSSEI- 3574 Query: 2992 KDGCGQFPYDANIQIHWVSFL 3012 C + N Q+++ +F+ Sbjct: 3575 --NCNMNDFQDNRQLYYENFI 3593 Score = 52.0 bits (123), Expect = 1e-05 Identities = 122/611 (19%), Positives = 236/611 (38%), Gaps = 138/611 (22%) Query: 1274 LLHPINLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLNQEDLNLL---FRILT--ENL 1328 ++ N+ + R L + K P + G+L + + +N++ ++ L F +LT E Sbjct: 848 VVEKFNVHLQLERRLIYTSDPKYPGAVLSGNLPDLKIHINEDKISALKNCFALLTTPEMK 907 Query: 1329 CEGTEDLDKVKPRVQETGEIKEPLEISISQDVHDSKNTLTTGVEEIRSVDIINMLLNFEI 1388 T+ +K+ P+ ++ G S+ V + ++ + R V + + LL E Sbjct: 908 TSDTQIKEKIFPQEEQRG--------SLQDSVMNLTQSIVLLEQHTREVLVESQLLLAEF 959 Query: 1389 KEVVVTLMKKSEKKGRPLHELNVLQLGMEAKVKTYD----MTAKAYLKKISMQCF--DFT 1442 K V + E GR + L V + YD +T L +MQ + DF Sbjct: 960 K--VNCMQLGVESNGRYISVLKVFGTNAHFVKRPYDAEVSLTVHGLLLVDTMQTYGADFD 1017 Query: 1443 -------------------DSKGE-PLHIINSSNVTD----------------------E 1460 DS+ + P+ N +++TD E Sbjct: 1018 LLMASHKNLSFDIPTGSLRDSRAQSPVSGPNVAHLTDGATLNDRSATSVSLDKILTKEQE 1077 Query: 1461 PLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLHLEALLSFMDFLSSAAPFSEP 1520 L+K+ S+ P DST Q + + +LD++L+ E ++ + FL + P + Sbjct: 1078 SLIKLEYQFVSSECPSMNL--DSTLQVISLQVNNLDIILNPETIVELIGFLQKSFPKEKD 1135 Query: 1521 SSSEKESELKPLVGE-SRSIAVKAVSSNISQKDVFDLKITAELNAFNVFVC--------- 1570 S + PL+ + RS + + +++ ++ E++ N+ + Sbjct: 1136 DLSPQ-----PLMTDFERSFREQGTYQSTYEQNT---EVAVEIHRLNLLLLRTVGMANRE 1187 Query: 1571 DQKCNIADIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQSIHKKAVSILGDEV---- 1626 IA I G ++S+ D+ L + +M++ ++ + V +G+ V Sbjct: 1188 KYGRKIATASIGGTKVNVSMG-STFDMNGSLGCLQLMDLTQDNVKNQYVVSIGNSVGYEN 1246 Query: 1627 -------FRFQLTLYPDATEGEA----YADMSKVDGKLSFKVGCIQIVYVHKFF----MS 1671 F DA EA + + SK + L+ K+ + + KF +S Sbjct: 1247 IISDIGYFESVFVRMEDAALTEALSFTFVERSKQECFLNLKMASLHYNHSAKFLKELTLS 1306 Query: 1672 LLNFLNNFQTAKEALST--ATVQAAERAASSMK------------------------DLA 1705 + NF+ ++ +T TV A + A S DLA Sbjct: 1307 MDELEENFRGMLKSAATKVTTVLATKTAEYSEMVSLFETPRKTREPFILEENEIYGFDLA 1366 Query: 1706 QK---SFRLLMDINLKAPVIIIPQSSVSPNAVIADLGLIRVENKFSLVPMEHYSLPPVID 1762 + +L+++IN+++PV+ IP+ SP ++ LG I ++N F E S D Sbjct: 1367 SSHLDTVKLILNINIESPVVSIPRKPGSPELLVGHLGQIFIQN-FVAGDDESRS-----D 1420 Query: 1763 KMNIELTQLKL 1773 ++ +E+ +KL Sbjct: 1421 RLQVEIKDIKL 1431 Score = 39.7 bits (91), Expect = 0.054 Identities = 86/375 (22%), Positives = 148/375 (39%), Gaps = 50/375 (13%) Query: 1274 LLHPINLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLNQEDLNLLFRILTENLCEGTE 1333 L P L+ V RNL H VP + I G+L S++ SL+ L+ +L NL E E Sbjct: 2201 LTEPCRLKLQVERNLDKEISHTVPDISIHGNLSSVHCSLDLYKYKLIRGLLENNLGEPIE 2260 Query: 1334 DLDKVKPRVQETGEIKEP-LEISISQDVHDSKNTLTTGVEEIRSVDIINMLLNF---EIK 1389 + ++P ++++P + +S +V+ L +D++N+ L + K Sbjct: 2261 EF--MRPY-----DLQDPRIHTVLSGEVYTCMCFL---------IDMVNVSLELKDPKRK 2304 Query: 1390 EVVVTLMKKSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFD--FTDSKGE 1447 E +L + KK + L+E + T L SM FD + K Sbjct: 2305 EGAGSLARFDFKKCKLLYE------------SFSNQTKSINLVSHSMMAFDTRYAGQKTS 2352 Query: 1448 PLHIINSSNVTDEPLLKMLLTKADSD-GPEFKTIHDSTKQRLKVSFASLDLVLHLEALLS 1506 P + N + +P T+ F++ DS+ V +L + L + LL Sbjct: 2353 P-GMTNVFSCIFQPAKNSSTTQGSIQIELHFRSTKDSS--CFTVVLNNLRVFLIFDWLLL 2409 Query: 1507 FMDFLSSAAPF--------SEPSSSEKESELKPLVGESRSIAVKAVSSNISQKDVFDLKI 1558 DFL + + S +S ES + P +S + K S +S + ++K+ Sbjct: 2410 VHDFLHTPSDIKKQNHVTPSRHRNSSSESAIVPKTVKS-GVVTKRSSLPVSNERHLEVKV 2468 Query: 1559 TAELNAFNVFVCDQKCNIADIKIHGMDASISVKPKQTD--VFARLKDIIVMNVDLQSIHK 1616 F V + D C + I ++ KP+ D L I V + L + H Sbjct: 2469 NVTGTEF-VVIEDVSCFDTNAIILKGTTVLTYKPRFVDRPFSGSLFGIEVFSCRLGNEHD 2527 Query: 1617 KAVSILGDEVFRFQL 1631 A+SI+ + +L Sbjct: 2528 TALSIVDPVQIQMEL 2542 >gi|35493713 vacuolar protein sorting 13B isoform 5 [Homo sapiens] Length = 4022 Score = 107 bits (268), Expect = 2e-22 Identities = 69/264 (26%), Positives = 121/264 (45%), Gaps = 13/264 (4%) Query: 3309 KQEMFAVHSVNLLLKSIGATLT---DVDDLIFKLAYYEIRYQFYKRDQLIWSVVRHYSEQ 3365 K + VNLL+ SI A+L D + +E F QL+ ++ HY+ Sbjct: 3584 KLRKLVIQPVNLLV-SIHASLKLYIASDHTPLSFSVFERGPIFTTARQLVHALAMHYAAG 3642 Query: 3366 FLKQMYVLVLGLDVLGNPFGLIRGLSEGVEALFYEPFQGAVQGPEEFAEGLVIGVRSLFG 3425 L + +V LD+LG+P L+R + GV F P++G +GP F G+ G S Sbjct: 3643 ALFRAGWVVGSLDILGSPASLVRSIGNGVADFFRLPYEGLTRGPGAFVSGVSRGTTSFVK 3702 Query: 3426 HTVGGAAGVVSRITGSVGKGLAAITMDKEYQQKRREELSRQPRDFGDSLARGGKGFLRGV 3485 H G ++ + S+ + + +++D+E+ ++ E + P G+ L +G + Sbjct: 3703 HISKGTLTSITNLATSLARNMDRLSLDEEHYNRQEEWRRQLPESLGEGLRQGLSRLGISL 3762 Query: 3486 VGGVTGIITKPVEGAKKEG---------AAGFFKGIGKGLVGAVARPTGGIVDMASSTFQ 3536 +G + GI+ +P++ +K A G G+GKG++G +P GG ++ S T Sbjct: 3763 LGAIAGIVDQPMQNFQKTSEAQASAGHKAKGVISGVGKGIMGVFTKPIGGAAELVSQTGY 3822 Query: 3537 GIQRAAESTEEVSSLRPPRLIHED 3560 GI A ++ P +H D Sbjct: 3823 GILHGAGLSQLPKQRHQPSDLHAD 3846 Score = 84.0 bits (206), Expect = 3e-15 Identities = 62/213 (29%), Positives = 106/213 (49%), Gaps = 17/213 (7%) Query: 2 VLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENAL-SELDVPFKVKAG 60 +LES V +L ++ Y++NL S L+L +WGG+V L L++K + L EL +PF +G Sbjct: 1 MLESYVTPILMSYVNRYIKNLKPSDLQLSLWGGDVVLSKLELKLDVLEQELKLPFTFLSG 60 Query: 61 QIDKLTLKIPWKNLYGEAVVATLEGL--YLLVVPGASIKYDAVKEEKSLQDVKQKELSRI 118 I +L + +PW L E VV T+ + L + G +++ + + + S I Sbjct: 61 HIHELRIHVPWTKLGSEPVVITINTMECILKLKDGIQDDHESCGSNSTNRSTAESTKSSI 120 Query: 119 E-EALQKAAEKDKPKEAKKDTFVEKLATQVIKNVQVKITDIHIKY-EDDVTDPKRPLSFG 176 + +Q+AA D +V+ L +V+ NV + I ++ +KY EDD+ LS Sbjct: 121 KPRRMQQAAPTDPD---LPPGYVQSLIRRVVNNVNIVINNLILKYVEDDIV-----LSVN 172 Query: 177 VTLGELSLLTANEHWTPCI--LNEADKIIYKLI 207 +T E T E W ++ D ++ K+I Sbjct: 173 ITSAE--CYTVGELWDRAFMDISATDLVLRKVI 203 >gi|35493701 vacuolar protein sorting 13B isoform 1 [Homo sapiens] Length = 3997 Score = 107 bits (268), Expect = 2e-22 Identities = 69/264 (26%), Positives = 121/264 (45%), Gaps = 13/264 (4%) Query: 3309 KQEMFAVHSVNLLLKSIGATLT---DVDDLIFKLAYYEIRYQFYKRDQLIWSVVRHYSEQ 3365 K + VNLL+ SI A+L D + +E F QL+ ++ HY+ Sbjct: 3559 KLRKLVIQPVNLLV-SIHASLKLYIASDHTPLSFSVFERGPIFTTARQLVHALAMHYAAG 3617 Query: 3366 FLKQMYVLVLGLDVLGNPFGLIRGLSEGVEALFYEPFQGAVQGPEEFAEGLVIGVRSLFG 3425 L + +V LD+LG+P L+R + GV F P++G +GP F G+ G S Sbjct: 3618 ALFRAGWVVGSLDILGSPASLVRSIGNGVADFFRLPYEGLTRGPGAFVSGVSRGTTSFVK 3677 Query: 3426 HTVGGAAGVVSRITGSVGKGLAAITMDKEYQQKRREELSRQPRDFGDSLARGGKGFLRGV 3485 H G ++ + S+ + + +++D+E+ ++ E + P G+ L +G + Sbjct: 3678 HISKGTLTSITNLATSLARNMDRLSLDEEHYNRQEEWRRQLPESLGEGLRQGLSRLGISL 3737 Query: 3486 VGGVTGIITKPVEGAKKEG---------AAGFFKGIGKGLVGAVARPTGGIVDMASSTFQ 3536 +G + GI+ +P++ +K A G G+GKG++G +P GG ++ S T Sbjct: 3738 LGAIAGIVDQPMQNFQKTSEAQASAGHKAKGVISGVGKGIMGVFTKPIGGAAELVSQTGY 3797 Query: 3537 GIQRAAESTEEVSSLRPPRLIHED 3560 GI A ++ P +H D Sbjct: 3798 GILHGAGLSQLPKQRHQPSDLHAD 3821 Score = 84.0 bits (206), Expect = 3e-15 Identities = 62/213 (29%), Positives = 106/213 (49%), Gaps = 17/213 (7%) Query: 2 VLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENAL-SELDVPFKVKAG 60 +LES V +L ++ Y++NL S L+L +WGG+V L L++K + L EL +PF +G Sbjct: 1 MLESYVTPILMSYVNRYIKNLKPSDLQLSLWGGDVVLSKLELKLDVLEQELKLPFTFLSG 60 Query: 61 QIDKLTLKIPWKNLYGEAVVATLEGL--YLLVVPGASIKYDAVKEEKSLQDVKQKELSRI 118 I +L + +PW L E VV T+ + L + G +++ + + + S I Sbjct: 61 HIHELRIHVPWTKLGSEPVVITINTMECILKLKDGIQDDHESCGSNSTNRSTAESTKSSI 120 Query: 119 E-EALQKAAEKDKPKEAKKDTFVEKLATQVIKNVQVKITDIHIKY-EDDVTDPKRPLSFG 176 + +Q+AA D +V+ L +V+ NV + I ++ +KY EDD+ LS Sbjct: 121 KPRRMQQAAPTDPD---LPPGYVQSLIRRVVNNVNIVINNLILKYVEDDIV-----LSVN 172 Query: 177 VTLGELSLLTANEHWTPCI--LNEADKIIYKLI 207 +T E T E W ++ D ++ K+I Sbjct: 173 ITSAE--CYTVGELWDRAFMDISATDLVLRKVI 203 >gi|119874215 vacuolar protein sorting 13B isoform 4 [Homo sapiens] Length = 415 Score = 84.0 bits (206), Expect = 3e-15 Identities = 62/213 (29%), Positives = 106/213 (49%), Gaps = 17/213 (7%) Query: 2 VLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENAL-SELDVPFKVKAG 60 +LES V +L ++ Y++NL S L+L +WGG+V L L++K + L EL +PF +G Sbjct: 1 MLESYVTPILMSYVNRYIKNLKPSDLQLSLWGGDVVLSKLELKLDVLEQELKLPFTFLSG 60 Query: 61 QIDKLTLKIPWKNLYGEAVVATLEGL--YLLVVPGASIKYDAVKEEKSLQDVKQKELSRI 118 I +L + +PW L E VV T+ + L + G +++ + + + S I Sbjct: 61 HIHELRIHVPWTKLGSEPVVITINTMECILKLKDGIQDDHESCGSNSTNRSTAESTKSSI 120 Query: 119 E-EALQKAAEKDKPKEAKKDTFVEKLATQVIKNVQVKITDIHIKY-EDDVTDPKRPLSFG 176 + +Q+AA D +V+ L +V+ NV + I ++ +KY EDD+ LS Sbjct: 121 KPRRMQQAAPTDPD---LPPGYVQSLIRRVVNNVNIVINNLILKYVEDDIV-----LSVN 172 Query: 177 VTLGELSLLTANEHWTPCI--LNEADKIIYKLI 207 +T E T E W ++ D ++ K+I Sbjct: 173 ITSAE--CYTVGELWDRAFMDISATDLVLRKVI 203 >gi|35493725 vacuolar protein sorting 13B isoform 3 [Homo sapiens] Length = 863 Score = 84.0 bits (206), Expect = 3e-15 Identities = 62/213 (29%), Positives = 106/213 (49%), Gaps = 17/213 (7%) Query: 2 VLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENAL-SELDVPFKVKAG 60 +LES V +L ++ Y++NL S L+L +WGG+V L L++K + L EL +PF +G Sbjct: 1 MLESYVTPILMSYVNRYIKNLKPSDLQLSLWGGDVVLSKLELKLDVLEQELKLPFTFLSG 60 Query: 61 QIDKLTLKIPWKNLYGEAVVATLEGL--YLLVVPGASIKYDAVKEEKSLQDVKQKELSRI 118 I +L + +PW L E VV T+ + L + G +++ + + + S I Sbjct: 61 HIHELRIHVPWTKLGSEPVVITINTMECILKLKDGIQDDHESCGSNSTNRSTAESTKSSI 120 Query: 119 E-EALQKAAEKDKPKEAKKDTFVEKLATQVIKNVQVKITDIHIKY-EDDVTDPKRPLSFG 176 + +Q+AA D +V+ L +V+ NV + I ++ +KY EDD+ LS Sbjct: 121 KPRRMQQAAPTDPD---LPPGYVQSLIRRVVNNVNIVINNLILKYVEDDIV-----LSVN 172 Query: 177 VTLGELSLLTANEHWTPCI--LNEADKIIYKLI 207 +T E T E W ++ D ++ K+I Sbjct: 173 ITSAE--CYTVGELWDRAFMDISATDLVLRKVI 203 >gi|118197272 ATG2 autophagy related 2 homolog B [Homo sapiens] Length = 2078 Score = 51.6 bits (122), Expect = 1e-05 Identities = 51/221 (23%), Positives = 103/221 (46%), Gaps = 19/221 (8%) Query: 10 LLNRFLGDYV-ENLNKSQLKLGIWGGNVALDNLQIKENALSEL----DVPFKVKAGQIDK 64 LL R+LG ++ E L+ QL L ++ G +L + + + L+E+ D P +V G I Sbjct: 17 LLQRYLGHFLQEKLSLEQLSLDLYQGTGSLAQVPLDKWCLNEILESADAPLEVTEGFIQS 76 Query: 65 LTLKIPWKNLYGEAVVATLEGLYLLVVP------GASIKYDAVKEEKSLQDVKQKELSRI 118 ++L +PW +L + + GL ++ P G+ Y + S+Q K+ ++ Sbjct: 77 ISLSVPWGSLLQDNCALEVRGLEMVFRPRPRPATGSEPMYWSSFMTSSMQLAKECLSQKL 136 Query: 119 EEALQKAAEKDKPKEAKKDTFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVT 178 + + E +P E + F E + T V++ V+V D ++ E + K + + Sbjct: 137 TD---EQGEGSQPFEG-LEKFAETIET-VLRRVKVTFIDTVLRIEHVPENSKTGTALEIR 191 Query: 179 LGELSLL--TANEHWTPCILNEADKIIYKLIRLDSLSAYWN 217 + TA+E + +++ +KL++L +S +W+ Sbjct: 192 IERTVYCDETADES-SGINVHQPTAFAHKLLQLSGVSLFWD 231 >gi|239745153 PREDICTED: similar to Putative golgin subfamily A member 6-like protein 6 [Homo sapiens] Length = 655 Score = 41.2 bits (95), Expect = 0.019 Identities = 33/141 (23%), Positives = 69/141 (48%), Gaps = 19/141 (13%) Query: 342 HIRRYTQMWSWSNIKKHRQLLKSYKIAYKNKLTQSKV------SEEIQKEIQDLEKTLDV 395 +I + T+ +++ +R + ++ KN Q K+ EIQ ++DL++ L+ Sbjct: 191 YIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLER 250 Query: 396 FNIILARQQAQVEVIRSGQKLRKKSADTG---EKRGGW-------FSGLWGKKESKKKDE 445 ++L +QQ QVE R G++L+ SA E+ W +W ++E ++ E Sbjct: 251 AQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQE 310 Query: 446 ESLIPETIDDLMTPEEKDKLF 466 E + + +L E+++K++ Sbjct: 311 EKMCEQ---ELKIREQEEKMW 328 >gi|239745127 PREDICTED: similar to Putative golgin subfamily A member 6-like protein 6 [Homo sapiens] Length = 655 Score = 40.8 bits (94), Expect = 0.024 Identities = 33/141 (23%), Positives = 69/141 (48%), Gaps = 19/141 (13%) Query: 342 HIRRYTQMWSWSNIKKHRQLLKSYKIAYKNKLTQSKV------SEEIQKEIQDLEKTLDV 395 +I + T+ +++ +R + ++ KN Q K+ EIQ ++DL++ L+ Sbjct: 191 YIEKLTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLER 250 Query: 396 FNIILARQQAQVEVIRSGQKLRKKSADTG---EKRGGW-------FSGLWGKKESKKKDE 445 ++L +QQ QVE R G++L+ SA E+ W +W ++E ++ E Sbjct: 251 AQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQE 310 Query: 446 ESLIPETIDDLMTPEEKDKLF 466 E + + +L E+++K++ Sbjct: 311 EKMCEQ---ELKIREQEEKMW 328 >gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sapiens] Length = 570 Score = 38.1 bits (87), Expect = 0.16 Identities = 29/102 (28%), Positives = 54/102 (52%), Gaps = 3/102 (2%) Query: 363 KSYKIAYKNKLTQSKVSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKSA- 421 K+ K+ K +L +S+ SE IQ +++L++ L+ ++L +QQ Q E G++L+ SA Sbjct: 210 KNAKLQEKLQLVESEKSE-IQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAK 268 Query: 422 -DTGEKRGGWFSGLWGKKESKKKDEESLIPETIDDLMTPEEK 462 + ++ L ++E K +E I E + + EEK Sbjct: 269 LQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEK 310 >gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 750 Score = 37.7 bits (86), Expect = 0.21 Identities = 29/102 (28%), Positives = 54/102 (52%), Gaps = 3/102 (2%) Query: 363 KSYKIAYKNKLTQSKVSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKSA- 421 K+ K+ K +L +S+ SE IQ +++L++ L+ ++L +QQ Q E G++L+ SA Sbjct: 222 KNAKLQEKLQLVESEKSE-IQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAK 280 Query: 422 -DTGEKRGGWFSGLWGKKESKKKDEESLIPETIDDLMTPEEK 462 + ++ L ++E K +E I E + + EEK Sbjct: 281 LQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEK 322 >gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 668 Score = 37.7 bits (86), Expect = 0.21 Identities = 29/102 (28%), Positives = 54/102 (52%), Gaps = 3/102 (2%) Query: 363 KSYKIAYKNKLTQSKVSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKSA- 421 K+ K+ K +L +S+ SE IQ +++L++ L+ ++L +QQ Q E G++L+ SA Sbjct: 222 KNAKLQEKLQLVESEKSE-IQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAK 280 Query: 422 -DTGEKRGGWFSGLWGKKESKKKDEESLIPETIDDLMTPEEK 462 + ++ L ++E K +E I E + + EEK Sbjct: 281 LQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEK 322 >gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like protein 6 [Homo sapiens] Length = 724 Score = 37.7 bits (86), Expect = 0.21 Identities = 29/102 (28%), Positives = 54/102 (52%), Gaps = 3/102 (2%) Query: 363 KSYKIAYKNKLTQSKVSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKSA- 421 K+ K+ K +L +S+ SE IQ +++L++ L+ ++L +QQ Q E G++L+ SA Sbjct: 283 KNAKLQEKLQLVESEKSE-IQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAK 341 Query: 422 -DTGEKRGGWFSGLWGKKESKKKDEESLIPETIDDLMTPEEK 462 + ++ L ++E K +E I E + + EEK Sbjct: 342 LQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEK 383 >gi|55770834 centromere protein F [Homo sapiens] Length = 3114 Score = 37.7 bits (86), Expect = 0.21 Identities = 43/207 (20%), Positives = 87/207 (42%), Gaps = 24/207 (11%) Query: 1303 GHLDSMNVSLNQEDLNLLFRILTENLCEGTEDLDK---------------VKPRVQETGE 1347 G L +N SLNQE +NL+ + +E+ ++ +K + R +ETG Sbjct: 977 GTLKEINASLNQEKMNLIQK--SESFANYIDEREKSISELSDQYKQEKLILLQRCEETGN 1034 Query: 1348 IKEPL--EISISQDVHDSKNTLT---TGVEEIRSVDIINMLLNF--EIKEVVVTLMKKSE 1400 E L + +Q+ + L T + E R ++ + F E +E + L E Sbjct: 1035 AYEDLSQKYKAAQEKNSKLECLLNECTSLCENRKNELEQLKEAFAKEHQEFLTKLAFAEE 1094 Query: 1401 KKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFDFTDSKGEPLHIINSSNVTDE 1460 + + EL +Q + +++ +K+ + + + + + +N +E Sbjct: 1095 RNQNLMLELETVQQALRSEMTDNQNNSKSEAGGLKQEIMTLKEEQNKMQKEVNDLLQENE 1154 Query: 1461 PLLKMLLTKADSDGPEFKTIHDSTKQR 1487 L+K++ TK + E + I +S K+R Sbjct: 1155 QLMKVMKTKHECQNLESEPIRNSVKER 1181 >gi|13699824 kinesin family member 11 [Homo sapiens] Length = 1056 Score = 37.4 bits (85), Expect = 0.27 Identities = 73/355 (20%), Positives = 144/355 (40%), Gaps = 58/355 (16%) Query: 370 KNKLTQSKVSEEIQKEIQDLEKT---LDVFNIILARQQAQVEVIRSGQK----LRKKSAD 422 KN+L Q K ++Q + Q+LE T L + L +++ + S ++ K + Sbjct: 444 KNELDQCK--SDLQNKTQELETTQKHLQETKLQLVKEEYITSALESTEEKLHDAASKLLN 501 Query: 423 TGEKRGGWFSGLWGKKESKKK------DEESLIPETIDDLMTPEEKDKLFTAIGYSESTH 476 T E+ SGL K + KK + + + + ++ L E+ G S+ Sbjct: 502 TVEETTKDVSGLHSKLDRKKAVDQHNAEAQDIFGKNLNSLFNNMEE---LIKDGSSKQKA 558 Query: 477 NLTLPKQYVAHIMTLKLVS----TSVTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKV 532 L + K ++++ + + T+V + +IPE + + + + + Q+L Sbjct: 559 MLEVHKTLFGNLLSSSVSALDTITTVALGSLTSIPENVSTHVSQIFNMILKE---QSLAA 615 Query: 533 EAKLEHWYITGLRQQDIVPSLVASIGDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVI 592 E+K + + + D++ SL + T S+LKI SQ + Sbjct: 616 ESKTVLQELINVLKTDLLSSLEMILSPTVVSILKI-----------------NSQLKHIF 658 Query: 593 YDAKTVNAVVEFFQSNKGLDLEQITSATLMKLEEIKERTATGLTHIIETRKVLDLRINLK 652 + TV +E ++ +L+ S L E++E T + ++E++K NL Sbjct: 659 KTSLTVADKIE----DQKKELDGFLSILCNNLHELQENT---ICSLVESQKQCG---NLT 708 Query: 653 PSYLVVPQTGFHHEKSDLLILDFGTFQ---LNSKDQGLQKTTNSSLEEIMDKAYD 704 + QT H + +++ T + L K + +QK +S E I K+ D Sbjct: 709 EDLKTIKQT---HSQELCKLMNLWTERFCALEEKCENIQKPLSSVQENIQQKSKD 760 >gi|239746976 PREDICTED: similar to paraneoplastic antigen MA1 [Homo sapiens] Length = 601 Score = 36.6 bits (83), Expect = 0.46 Identities = 36/114 (31%), Positives = 44/114 (38%), Gaps = 30/114 (26%) Query: 3404 GAVQGPEEFAEGLVIGVRSLFGHTVGGAAGVVSRITGSVGKGLAAITMDKEYQQKRREEL 3463 G QGP+ EG G RSL G G V+ + G+VG+ Sbjct: 67 GPAQGPQREEEGAP-GCRSLVGRGWGVGWAAVAEVQGTVGE------------------- 106 Query: 3464 SRQPRDFGDSLARGGKGFLRGVVGGVTG---IITKPVEGAKKEGAAGFFKGIGK 3514 R FG GG+G L VGG G + K G KEG +F G GK Sbjct: 107 -RGALAFG-----GGRGLLAAGVGGAEGGCQVTRKIKRGRSKEGGGSWF-GAGK 153 >gi|169217313 PREDICTED: similar to paraneoplastic antigen MA1 [Homo sapiens] Length = 601 Score = 36.2 bits (82), Expect = 0.60 Identities = 36/114 (31%), Positives = 44/114 (38%), Gaps = 30/114 (26%) Query: 3404 GAVQGPEEFAEGLVIGVRSLFGHTVGGAAGVVSRITGSVGKGLAAITMDKEYQQKRREEL 3463 G QGP+ EG G RSL G G V+ + G+VG+ Sbjct: 67 GPAQGPQREEEGAP-GCRSLVGRGWGVGWAAVAEVQGTVGE------------------- 106 Query: 3464 SRQPRDFGDSLARGGKGFLRGVVGGVTG---IITKPVEGAKKEGAAGFFKGIGK 3514 R FG GG+G L VGG G + K G KEG +F G GK Sbjct: 107 -RGACAFG-----GGRGLLAAGVGGAEGGCQVTRKIKRGRSKEGGGSWF-GAGK 153 >gi|32880208 diaphanous homolog 3 isoform b [Homo sapiens] Length = 849 Score = 36.2 bits (82), Expect = 0.60 Identities = 38/156 (24%), Positives = 69/156 (44%), Gaps = 16/156 (10%) Query: 1050 FCVIVCNEK-----NNIAEIKIQGLDSSLSLQSRKQSL------FARLENIIVTDVDPKT 1098 F V +C EK N + +++ S +S+++ +++L +LE + T P+ Sbjct: 622 FLVEICEEKYPDILNFVDDLEPLDKASKVSVETLEKNLRQMGRQLQQLEKELETFPPPED 681 Query: 1099 VHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMSKV-DGVLSLNVGCIQIVYLHKFLMSL 1157 +H K V+ M V T L+ +M K+ ++ ++ V + FL L Sbjct: 682 LHDKFVTKMSRFVISAKEQY---ETLSKLHENMEKLYQSIIGYYAIDVKKVSVEDFLTDL 738 Query: 1158 LNFLNNF-QTAKESLSAATAQAAERAATSVKDLAQR 1192 NF F Q KE++ A+ E+ K+LA+R Sbjct: 739 NNFRTTFMQAIKENIKKREAEEKEKRVRIAKELAER 774 >gi|110225351 diaphanous homolog 3 isoform a [Homo sapiens] Length = 1193 Score = 36.2 bits (82), Expect = 0.60 Identities = 38/156 (24%), Positives = 69/156 (44%), Gaps = 16/156 (10%) Query: 1050 FCVIVCNEK-----NNIAEIKIQGLDSSLSLQSRKQSL------FARLENIIVTDVDPKT 1098 F V +C EK N + +++ S +S+++ +++L +LE + T P+ Sbjct: 885 FLVEICEEKYPDILNFVDDLEPLDKASKVSVETLEKNLRQMGRQLQQLEKELETFPPPED 944 Query: 1099 VHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMSKV-DGVLSLNVGCIQIVYLHKFLMSL 1157 +H K V+ M V T L+ +M K+ ++ ++ V + FL L Sbjct: 945 LHDKFVTKMSRFVISAKEQY---ETLSKLHENMEKLYQSIIGYYAIDVKKVSVEDFLTDL 1001 Query: 1158 LNFLNNF-QTAKESLSAATAQAAERAATSVKDLAQR 1192 NF F Q KE++ A+ E+ K+LA+R Sbjct: 1002 NNFRTTFMQAIKENIKKREAEEKEKRVRIAKELAER 1037 >gi|51988900 XPG-complementing protein [Homo sapiens] Length = 1186 Score = 35.8 bits (81), Expect = 0.78 Identities = 54/230 (23%), Positives = 94/230 (40%), Gaps = 31/230 (13%) Query: 687 LQKTTNSSLEEIMDKAYDKFDVEIKNVQLLFARAEETWKKCRFQHPSTMHILQPMDIHVE 746 LQ+T SS+ + +A D ++NV A+ E + + + +T Q + + Sbjct: 583 LQET--SSIVSVPSEAVDN----VENVVSFNAKEHENFLETIQEQQTTESAGQDL---IS 633 Query: 747 LAKAMVEKDIRMARFKVSGGLPLMHVRISDQKMKDVLYLMNSIPLPQKSSAQSPERQVSS 806 + KA+ +I + G + ISD++++ A+ PE +S Sbjct: 634 IPKAVEPMEIDSEESESDGSFIEVQSVISDEELQ----------------AEFPE---TS 674 Query: 807 IPIISGGTKGLLGTSLLLDTVESES---DDEYFDAEDGEPQTCKSMKGSELKKAAEVPNE 863 P G + L+GT ESES D+ D DGEPQ + L + ++ E Sbjct: 675 KPPSEQGEEELVGTREGEAPAESESLLRDNSERDDVDGEPQEAEKDAEDSLHEWQDINLE 734 Query: 864 ELINLLLKFEIKEVILEFTKQQKEEDTILVFNVTQLGTEATMRTFDLTVV 913 EL L ++ L+ KQQ+E V L ++ +R F + + Sbjct: 735 ELETLESNLLAQQNSLKAQKQQQERIAATVTGQMFLESQELLRLFGIPYI 784 >gi|36031016 CTCL tumor antigen L14-2 [Homo sapiens] Length = 898 Score = 35.0 bits (79), Expect = 1.3 Identities = 62/325 (19%), Positives = 133/325 (40%), Gaps = 39/325 (12%) Query: 101 VKEEKSLQDVKQKELSRIEEALQKAAEKDKPKEAKKDTFV--EKLATQVIK---NVQVKI 155 V + ++Q + ++ R+E+A +K E + KEA +V EK + + K ++ K+ Sbjct: 277 VTAKNAVQQLHKEMAQRMEQANKKCEEARQEKEAMVMKYVRGEKESLDLRKEKETLEKKL 336 Query: 156 TDIHIKYEDDVTDPKRPLSFGVTLGEL-SLLTANEHWTPCILNEADKIIYKLIRLDSLSA 214 D + + E + K+ G L L E T ++ E DK + + I + Sbjct: 337 RDANKELEKNTNKIKQ---LSQEKGRLHQLYETKEGETTRLIREIDK-LKEDINSHVIKV 392 Query: 215 YWNVNCSMSYQRSREQILDQLKNEILTSGNIPPNYQYIFQPISASAKLYMNPYAESELKT 274 W N + S ++ D+LK I + K Y E+K+ Sbjct: 393 KWAQNKLKAEMDSHKETKDKLKETTTKLTQAKEEADQIRKNCQDMIKTYQE---SEEIKS 449 Query: 275 PKLDCNIEIQNIAIELTKPQYLSMIDLLESVDYMVRNAPYRKYKPYLPLHTNGRRWWKYA 334 +LD + + +E Q D LE + +A ++ + +R +K Sbjct: 450 NELDAKLRVTKGELE---KQMQEKSDQLE-----MHHAKIKELEDL-------KRTFKEG 494 Query: 335 IDSV----LEVHIRRYTQMWSWSNIKKHRQLLKSYKIAYKNKLTQSKVSEEIQ------- 383 +D + +V ++ + + K+++++ K +N L + K ++++Q Sbjct: 495 MDELRTLRTKVKCLEDERLRTEDELSKYKEIINRQKAEIQNLLDKVKTADQLQEQLQRGK 554 Query: 384 KEIQDLEKTLDVFNIILARQQAQVE 408 +EI++L++ ++ N ++ Q +E Sbjct: 555 QEIENLKEEVESLNSLINDLQKDIE 579 >gi|55749659 UHRF1 (ICBP90) binding protein 1-like isoform b [Homo sapiens] Length = 522 Score = 34.7 bits (78), Expect = 1.7 Identities = 34/192 (17%), Positives = 73/192 (38%), Gaps = 36/192 (18%) Query: 3 LESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSE-LDVPFKVKAGQ 61 + ++ + + L + +NL+ ++ L G L NL++ E L LD+P + + Sbjct: 1 MAGIIKKQILKHLSRFTKNLSPDKINLSTLKGEGELKNLELDEEVLQNMLDLPTWLAINK 60 Query: 62 I--DKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIE 119 + +K +++IPW L + +L+ + + E+S E Sbjct: 61 VFCNKASIRIPWTKLKTHPICLSLDKVIM-------------------------EMSTCE 95 Query: 120 EALQKAAEKDKPKEAKKDTFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTL 179 E ++ P A +V++ + V + I I+ + + L Sbjct: 96 E--PRSPNGPSPIATASGQSEYGFAEKVVEGISVSVNSIVIRI------GAKAFNASFEL 147 Query: 180 GELSLLTANEHW 191 +L + + N HW Sbjct: 148 SQLRIYSVNAHW 159 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.317 0.133 0.378 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 122,107,625 Number of Sequences: 37866 Number of extensions: 5251034 Number of successful extensions: 15661 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 18 Number of HSP's successfully gapped in prelim test: 33 Number of HSP's that attempted gapping in prelim test: 15238 Number of HSP's gapped (non-prelim): 210 length of query: 3585 length of database: 18,247,518 effective HSP length: 122 effective length of query: 3463 effective length of database: 13,627,866 effective search space: 47193299958 effective search space used: 47193299958 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 72 (32.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.