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Search of human proteins with 66347828
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|66347828 vacuolar protein sorting 13C protein isoform 2A
[Homo sapiens]
(3753 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|66347828 vacuolar protein sorting 13C protein isoform 2A [Hom... 7372 0.0
gi|42544121 vacuolar protein sorting 13C protein isoform 1A [Hom... 7260 0.0
gi|66347845 vacuolar protein sorting 13C protein isoform 2B [Hom... 7108 0.0
gi|66348091 vacuolar protein sorting 13C protein isoform 1B [Hom... 6995 0.0
gi|66346674 vacuolar protein sorting 13A isoform A [Homo sapiens] 1700 0.0
gi|15619008 vacuolar protein sorting 13A isoform B [Homo sapiens] 1679 0.0
gi|66346676 vacuolar protein sorting 13A isoform D [Homo sapiens] 1679 0.0
gi|66346672 vacuolar protein sorting 13A isoform C [Homo sapiens] 1649 0.0
gi|54607141 vacuolar protein sorting 13D isoform 2 [Homo sapiens] 218 9e-56
gi|54607139 vacuolar protein sorting 13D isoform 1 [Homo sapiens] 218 9e-56
gi|35493713 vacuolar protein sorting 13B isoform 5 [Homo sapiens] 107 2e-22
gi|35493701 vacuolar protein sorting 13B isoform 1 [Homo sapiens] 107 2e-22
gi|119874215 vacuolar protein sorting 13B isoform 4 [Homo sapiens] 72 1e-11
gi|35493725 vacuolar protein sorting 13B isoform 3 [Homo sapiens] 72 1e-11
gi|118197272 ATG2 autophagy related 2 homolog B [Homo sapiens] 44 0.002
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 41 0.020
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 41 0.026
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 38 0.17
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 38 0.22
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 38 0.22
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 38 0.22
gi|55770834 centromere protein F [Homo sapiens] 38 0.22
gi|13699824 kinesin family member 11 [Homo sapiens] 37 0.28
gi|239746976 PREDICTED: similar to paraneoplastic antigen MA1 [H... 37 0.48
gi|93204861 protein phosphatase 1, regulatory (inhibitor) subuni... 37 0.48
gi|169217313 PREDICTED: similar to paraneoplastic antigen MA1 [H... 36 0.63
gi|32880208 diaphanous homolog 3 isoform b [Homo sapiens] 36 0.63
gi|110225351 diaphanous homolog 3 isoform a [Homo sapiens] 36 0.63
gi|51988900 XPG-complementing protein [Homo sapiens] 36 0.82
gi|55749659 UHRF1 (ICBP90) binding protein 1-like isoform b [Hom... 34 2.4
>gi|66347828 vacuolar protein sorting 13C protein isoform 2A [Homo
sapiens]
Length = 3753
Score = 7372 bits (19128), Expect = 0.0
Identities = 3753/3753 (100%), Positives = 3753/3753 (100%)
Query: 1 MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAG 60
MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAG
Sbjct: 1 MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAG 60
Query: 61 QIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEE 120
QIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEE
Sbjct: 61 QIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEE 120
Query: 121 ALQKAAEKGTHSGEFIYGLENFVYKDIKPGRKRKKHKKHFKKPFKGLDRSKDKPKEAKKD 180
ALQKAAEKGTHSGEFIYGLENFVYKDIKPGRKRKKHKKHFKKPFKGLDRSKDKPKEAKKD
Sbjct: 121 ALQKAAEKGTHSGEFIYGLENFVYKDIKPGRKRKKHKKHFKKPFKGLDRSKDKPKEAKKD 180
Query: 181 TFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLGELSLLTANEHWTPCILN 240
TFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLGELSLLTANEHWTPCILN
Sbjct: 181 TFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLGELSLLTANEHWTPCILN 240
Query: 241 EADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILDQLKNEILTSGNIPPNYQYIFQPIS 300
EADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILDQLKNEILTSGNIPPNYQYIFQPIS
Sbjct: 241 EADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILDQLKNEILTSGNIPPNYQYIFQPIS 300
Query: 301 ASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKPQYLSMIDLLESVDYMVRNAPYRKY 360
ASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKPQYLSMIDLLESVDYMVRNAPYRKY
Sbjct: 301 ASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKPQYLSMIDLLESVDYMVRNAPYRKY 360
Query: 361 KPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIKKHRQLLKSYKIAYKNKLTQSK 420
KPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIKKHRQLLKSYKIAYKNKLTQSK
Sbjct: 361 KPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIKKHRQLLKSYKIAYKNKLTQSK 420
Query: 421 VSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKSADTGEKRGGWFSGLWGK 480
VSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKSADTGEKRGGWFSGLWGK
Sbjct: 421 VSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKSADTGEKRGGWFSGLWGK 480
Query: 481 KESKKKDEESLIPETIDDLMTPEEKDKLFTAIGYSESTHNLTLPKQYVAHIMTLKLVSTS 540
KESKKKDEESLIPETIDDLMTPEEKDKLFTAIGYSESTHNLTLPKQYVAHIMTLKLVSTS
Sbjct: 481 KESKKKDEESLIPETIDDLMTPEEKDKLFTAIGYSESTHNLTLPKQYVAHIMTLKLVSTS 540
Query: 541 VTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVEAKLEHWYITGLRQQDIVPSLVASI 600
VTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVEAKLEHWYITGLRQQDIVPSLVASI
Sbjct: 541 VTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVEAKLEHWYITGLRQQDIVPSLVASI 600
Query: 601 GDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIYDAKTVNAVVEFFQSNKGLDLEQIT 660
GDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIYDAKTVNAVVEFFQSNKGLDLEQIT
Sbjct: 601 GDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIYDAKTVNAVVEFFQSNKGLDLEQIT 660
Query: 661 SATLMKLEEIKERTATGLTHIIETRKVLDLRINLKPSYLVVPQTGFHHEKSDLLILDFGT 720
SATLMKLEEIKERTATGLTHIIETRKVLDLRINLKPSYLVVPQTGFHHEKSDLLILDFGT
Sbjct: 661 SATLMKLEEIKERTATGLTHIIETRKVLDLRINLKPSYLVVPQTGFHHEKSDLLILDFGT 720
Query: 721 FQLNSKDQGLQKTTNSSLEEIMDKAYDKFDVEIKNVQLLFARAEETWKKCRFQHPSTMHI 780
FQLNSKDQGLQKTTNSSLEEIMDKAYDKFDVEIKNVQLLFARAEETWKKCRFQHPSTMHI
Sbjct: 721 FQLNSKDQGLQKTTNSSLEEIMDKAYDKFDVEIKNVQLLFARAEETWKKCRFQHPSTMHI 780
Query: 781 LQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVRISDQKMKDVLYLMNSIPLPQKSSA 840
LQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVRISDQKMKDVLYLMNSIPLPQKSSA
Sbjct: 781 LQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVRISDQKMKDVLYLMNSIPLPQKSSA 840
Query: 841 QSPERQVSSIPIISGGTKGLLGTSLLLDTVESESDDEYFDAEDGEPQTCKSMKGSELKKA 900
QSPERQVSSIPIISGGTKGLLGTSLLLDTVESESDDEYFDAEDGEPQTCKSMKGSELKKA
Sbjct: 841 QSPERQVSSIPIISGGTKGLLGTSLLLDTVESESDDEYFDAEDGEPQTCKSMKGSELKKA 900
Query: 901 AEVPNEELINLLLKFEIKEVILEFTKQQKEEDTILVFNVTQLGTEATMRTFDLTVVSYLK 960
AEVPNEELINLLLKFEIKEVILEFTKQQKEEDTILVFNVTQLGTEATMRTFDLTVVSYLK
Sbjct: 901 AEVPNEELINLLLKFEIKEVILEFTKQQKEEDTILVFNVTQLGTEATMRTFDLTVVSYLK 960
Query: 961 KISLDYHEIEGSKRKPLHLISSSDKPGLDLLKVEYIKADKNGPSFQTAFGKTEQTVKVAF 1020
KISLDYHEIEGSKRKPLHLISSSDKPGLDLLKVEYIKADKNGPSFQTAFGKTEQTVKVAF
Sbjct: 961 KISLDYHEIEGSKRKPLHLISSSDKPGLDLLKVEYIKADKNGPSFQTAFGKTEQTVKVAF 1020
Query: 1021 SSLNLLLQTQALVASINYLTTIIPSDDQSISVAKEVQISTEKQQKNSTLPKAIVSSRDSD 1080
SSLNLLLQTQALVASINYLTTIIPSDDQSISVAKEVQISTEKQQKNSTLPKAIVSSRDSD
Sbjct: 1021 SSLNLLLQTQALVASINYLTTIIPSDDQSISVAKEVQISTEKQQKNSTLPKAIVSSRDSD 1080
Query: 1081 IIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSSLSLQSRKQSLFARLENIIVTDVDPK 1140
IIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSSLSLQSRKQSLFARLENIIVTDVDPK
Sbjct: 1081 IIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSSLSLQSRKQSLFARLENIIVTDVDPK 1140
Query: 1141 TVHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMSKVDGVLSLNVGCIQIVYLHKFLMSL 1200
TVHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMSKVDGVLSLNVGCIQIVYLHKFLMSL
Sbjct: 1141 TVHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMSKVDGVLSLNVGCIQIVYLHKFLMSL 1200
Query: 1201 LNFLNNFQTAKESLSAATAQAAERAATSVKDLAQRSFRVSINIDLKAPVIVIPQSSISTN 1260
LNFLNNFQTAKESLSAATAQAAERAATSVKDLAQRSFRVSINIDLKAPVIVIPQSSISTN
Sbjct: 1201 LNFLNNFQTAKESLSAATAQAAERAATSVKDLAQRSFRVSINIDLKAPVIVIPQSSISTN 1260
Query: 1261 AVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQLTKLTLYRTVIQPGIYHPDIQLLHP 1320
AVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQLTKLTLYRTVIQPGIYHPDIQLLHP
Sbjct: 1261 AVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQLTKLTLYRTVIQPGIYHPDIQLLHP 1320
Query: 1321 INLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLNQEDLNLLFRILTENLCEGTEDLDK 1380
INLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLNQEDLNLLFRILTENLCEGTEDLDK
Sbjct: 1321 INLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLNQEDLNLLFRILTENLCEGTEDLDK 1380
Query: 1381 VKPRVQETGEIKEPLEISISQDVHDSKNTLTTGVEEIRSVDIINMLLNFEIKEVVVTLMK 1440
VKPRVQETGEIKEPLEISISQDVHDSKNTLTTGVEEIRSVDIINMLLNFEIKEVVVTLMK
Sbjct: 1381 VKPRVQETGEIKEPLEISISQDVHDSKNTLTTGVEEIRSVDIINMLLNFEIKEVVVTLMK 1440
Query: 1441 KSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFDFTDSKGEPLHIINSSNV 1500
KSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFDFTDSKGEPLHIINSSNV
Sbjct: 1441 KSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFDFTDSKGEPLHIINSSNV 1500
Query: 1501 TDEPLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLHLEALLSFMDFLSSAAPF 1560
TDEPLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLHLEALLSFMDFLSSAAPF
Sbjct: 1501 TDEPLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLHLEALLSFMDFLSSAAPF 1560
Query: 1561 SEPSSSEKESELKPLVGESRSIAVKAVSSNISQKDVFDLKITAELNAFNVFVCDQKCNIA 1620
SEPSSSEKESELKPLVGESRSIAVKAVSSNISQKDVFDLKITAELNAFNVFVCDQKCNIA
Sbjct: 1561 SEPSSSEKESELKPLVGESRSIAVKAVSSNISQKDVFDLKITAELNAFNVFVCDQKCNIA 1620
Query: 1621 DIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQSIHKKAVSILGDEVFRFQLTLYPDA 1680
DIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQSIHKKAVSILGDEVFRFQLTLYPDA
Sbjct: 1621 DIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQSIHKKAVSILGDEVFRFQLTLYPDA 1680
Query: 1681 TEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQTAKEALSTATVQAAERA 1740
TEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQTAKEALSTATVQAAERA
Sbjct: 1681 TEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQTAKEALSTATVQAAERA 1740
Query: 1741 ASSMKDLAQKSFRLLMDINLKAPVIIIPQSSVSPNAVIADLGLIRVENKFSLVPMEHYSL 1800
ASSMKDLAQKSFRLLMDINLKAPVIIIPQSSVSPNAVIADLGLIRVENKFSLVPMEHYSL
Sbjct: 1741 ASSMKDLAQKSFRLLMDINLKAPVIIIPQSSVSPNAVIADLGLIRVENKFSLVPMEHYSL 1800
Query: 1801 PPVIDKMNIELTQLKLSRTILQASLPQNDIEILKPVNMLLSIQRNLAAAWYVQIPGMEIK 1860
PPVIDKMNIELTQLKLSRTILQASLPQNDIEILKPVNMLLSIQRNLAAAWYVQIPGMEIK
Sbjct: 1801 PPVIDKMNIELTQLKLSRTILQASLPQNDIEILKPVNMLLSIQRNLAAAWYVQIPGMEIK 1860
Query: 1861 GKLKPMQVALSEDDLTVLMKILLENLGEASSQPSPTQSVQETVRVRKVDVSSVPDHLKEQ 1920
GKLKPMQVALSEDDLTVLMKILLENLGEASSQPSPTQSVQETVRVRKVDVSSVPDHLKEQ
Sbjct: 1861 GKLKPMQVALSEDDLTVLMKILLENLGEASSQPSPTQSVQETVRVRKVDVSSVPDHLKEQ 1920
Query: 1921 EDWTDSKLSMNQIVSLQFDFHFESLSIILYNNDINQESGVAFHNDSFQLGELRLHLMASS 1980
EDWTDSKLSMNQIVSLQFDFHFESLSIILYNNDINQESGVAFHNDSFQLGELRLHLMASS
Sbjct: 1921 EDWTDSKLSMNQIVSLQFDFHFESLSIILYNNDINQESGVAFHNDSFQLGELRLHLMASS 1980
Query: 1981 GKMFKDGSMNVSVKLKTCTLDDLREGIERATSRMIDRKNDQDNNSSMIDISYKQDKNGSQ 2040
GKMFKDGSMNVSVKLKTCTLDDLREGIERATSRMIDRKNDQDNNSSMIDISYKQDKNGSQ
Sbjct: 1981 GKMFKDGSMNVSVKLKTCTLDDLREGIERATSRMIDRKNDQDNNSSMIDISYKQDKNGSQ 2040
Query: 2041 IDAVLDKLYVCASVEFLMTVADFFIKAVPQSPENVAKETQILPRQTATGKVKIEKDDSVR 2100
IDAVLDKLYVCASVEFLMTVADFFIKAVPQSPENVAKETQILPRQTATGKVKIEKDDSVR
Sbjct: 2041 IDAVLDKLYVCASVEFLMTVADFFIKAVPQSPENVAKETQILPRQTATGKVKIEKDDSVR 2100
Query: 2101 PNMTLKAMITDPEVVFVASLTKADAPALTASFQCNLSLSTSKLEQMMEASVRDLKVLACP 2160
PNMTLKAMITDPEVVFVASLTKADAPALTASFQCNLSLSTSKLEQMMEASVRDLKVLACP
Sbjct: 2101 PNMTLKAMITDPEVVFVASLTKADAPALTASFQCNLSLSTSKLEQMMEASVRDLKVLACP 2160
Query: 2161 FLREKRGKNITTVLQPCSLFMEKCTWASGKQNINIMVKEFIIKISPIILNTVLTIMAALS 2220
FLREKRGKNITTVLQPCSLFMEKCTWASGKQNINIMVKEFIIKISPIILNTVLTIMAALS
Sbjct: 2161 FLREKRGKNITTVLQPCSLFMEKCTWASGKQNINIMVKEFIIKISPIILNTVLTIMAALS 2220
Query: 2221 PKTKEDGSKDTSKEMENLWGIKSINDYNTWFLGVDTATEITESFKGIEHSLIEENCGVVV 2280
PKTKEDGSKDTSKEMENLWGIKSINDYNTWFLGVDTATEITESFKGIEHSLIEENCGVVV
Sbjct: 2221 PKTKEDGSKDTSKEMENLWGIKSINDYNTWFLGVDTATEITESFKGIEHSLIEENCGVVV 2280
Query: 2281 ESIQVTLECGLGHRTVPLLLAESKFSGNIKNWTSLMAAVADVTLQVHYYNEIHAVWEPLI 2340
ESIQVTLECGLGHRTVPLLLAESKFSGNIKNWTSLMAAVADVTLQVHYYNEIHAVWEPLI
Sbjct: 2281 ESIQVTLECGLGHRTVPLLLAESKFSGNIKNWTSLMAAVADVTLQVHYYNEIHAVWEPLI 2340
Query: 2341 ERVEGKRQWNLRLDVKKNPVQDKSLLPGDDFIPEPQMAIHISSGNTMNITISKSCLNVFN 2400
ERVEGKRQWNLRLDVKKNPVQDKSLLPGDDFIPEPQMAIHISSGNTMNITISKSCLNVFN
Sbjct: 2341 ERVEGKRQWNLRLDVKKNPVQDKSLLPGDDFIPEPQMAIHISSGNTMNITISKSCLNVFN 2400
Query: 2401 NLAKGFSEGTASTFDYSLKDRAPFTVKNAVGVPIKVKPNCNLRVMGFPEKSDIFDVDAGQ 2460
NLAKGFSEGTASTFDYSLKDRAPFTVKNAVGVPIKVKPNCNLRVMGFPEKSDIFDVDAGQ
Sbjct: 2401 NLAKGFSEGTASTFDYSLKDRAPFTVKNAVGVPIKVKPNCNLRVMGFPEKSDIFDVDAGQ 2460
Query: 2461 NLELEYASMVPSSQGNLSILSRQESSFFTLTIVPHGYTEVANIPVARPGRRLYNVRNPNA 2520
NLELEYASMVPSSQGNLSILSRQESSFFTLTIVPHGYTEVANIPVARPGRRLYNVRNPNA
Sbjct: 2461 NLELEYASMVPSSQGNLSILSRQESSFFTLTIVPHGYTEVANIPVARPGRRLYNVRNPNA 2520
Query: 2521 SHSDSVLVQIDATEGNKVITLRSPLQIKNHFSIAFIIYKFVKNVKLLERIGIARPEEEFH 2580
SHSDSVLVQIDATEGNKVITLRSPLQIKNHFSIAFIIYKFVKNVKLLERIGIARPEEEFH
Sbjct: 2521 SHSDSVLVQIDATEGNKVITLRSPLQIKNHFSIAFIIYKFVKNVKLLERIGIARPEEEFH 2580
Query: 2581 VPLDSYRCQLFIQPAGILEHQYKESTTYISWKEELHRSREVRCMLQCPSVEVSFLPLIVN 2640
VPLDSYRCQLFIQPAGILEHQYKESTTYISWKEELHRSREVRCMLQCPSVEVSFLPLIVN
Sbjct: 2581 VPLDSYRCQLFIQPAGILEHQYKESTTYISWKEELHRSREVRCMLQCPSVEVSFLPLIVN 2640
Query: 2641 TVALPDELSYICTHGEDWDVAYIIHLYPSLTLRNLLPYSLRYLLEGTAETHELAEGSTAD 2700
TVALPDELSYICTHGEDWDVAYIIHLYPSLTLRNLLPYSLRYLLEGTAETHELAEGSTAD
Sbjct: 2641 TVALPDELSYICTHGEDWDVAYIIHLYPSLTLRNLLPYSLRYLLEGTAETHELAEGSTAD 2700
Query: 2701 VLHSRISGEIMELVLVKYQGKNWNGHFRIRDTLPEFFPVCFSSDSTEVTTVDLSVHVRRI 2760
VLHSRISGEIMELVLVKYQGKNWNGHFRIRDTLPEFFPVCFSSDSTEVTTVDLSVHVRRI
Sbjct: 2701 VLHSRISGEIMELVLVKYQGKNWNGHFRIRDTLPEFFPVCFSSDSTEVTTVDLSVHVRRI 2760
Query: 2761 GSRMVLSVFSPYWLINKTTRVLQYRSEDIHVKHPADFRDIILFSFKKKNIFTKNKVQLKI 2820
GSRMVLSVFSPYWLINKTTRVLQYRSEDIHVKHPADFRDIILFSFKKKNIFTKNKVQLKI
Sbjct: 2761 GSRMVLSVFSPYWLINKTTRVLQYRSEDIHVKHPADFRDIILFSFKKKNIFTKNKVQLKI 2820
Query: 2821 STSAWSSSFSLDTVGSYGCVKCPANNMEYLVGVSIKMSSFNLSRIVTLTPFCTIANKSSL 2880
STSAWSSSFSLDTVGSYGCVKCPANNMEYLVGVSIKMSSFNLSRIVTLTPFCTIANKSSL
Sbjct: 2821 STSAWSSSFSLDTVGSYGCVKCPANNMEYLVGVSIKMSSFNLSRIVTLTPFCTIANKSSL 2880
Query: 2881 ELEVGEIASDGSMPTNKWNYIASSECLPFWPESLSGKLCVRVVGCEGSSKPFFYNRQDNG 2940
ELEVGEIASDGSMPTNKWNYIASSECLPFWPESLSGKLCVRVVGCEGSSKPFFYNRQDNG
Sbjct: 2881 ELEVGEIASDGSMPTNKWNYIASSECLPFWPESLSGKLCVRVVGCEGSSKPFFYNRQDNG 2940
Query: 2941 TLLSLEDLNGGILVDVNTAEHSTVITFSDYHEGSAPALIMNHTPWDILTYKQSGSPEEMV 3000
TLLSLEDLNGGILVDVNTAEHSTVITFSDYHEGSAPALIMNHTPWDILTYKQSGSPEEMV
Sbjct: 2941 TLLSLEDLNGGILVDVNTAEHSTVITFSDYHEGSAPALIMNHTPWDILTYKQSGSPEEMV 3000
Query: 3001 LLPRQARLFAWADPTGTRKLTWTYAANVGEHDLLKDGCGQFPYDANIQIHWVSFLDGRQR 3060
LLPRQARLFAWADPTGTRKLTWTYAANVGEHDLLKDGCGQFPYDANIQIHWVSFLDGRQR
Sbjct: 3001 LLPRQARLFAWADPTGTRKLTWTYAANVGEHDLLKDGCGQFPYDANIQIHWVSFLDGRQR 3060
Query: 3061 VLLFTDDVALVSKALQAEEMEQADYEITLSLHSLGLSLVNNESKQEVSYIGITSSGVVWE 3120
VLLFTDDVALVSKALQAEEMEQADYEITLSLHSLGLSLVNNESKQEVSYIGITSSGVVWE
Sbjct: 3061 VLLFTDDVALVSKALQAEEMEQADYEITLSLHSLGLSLVNNESKQEVSYIGITSSGVVWE 3120
Query: 3121 VKPKQKWKPFSQKQIILLEQSYQKHQISRDHGWIKLDNNFEVNFDKDPMEMRLPIRSPIK 3180
VKPKQKWKPFSQKQIILLEQSYQKHQISRDHGWIKLDNNFEVNFDKDPMEMRLPIRSPIK
Sbjct: 3121 VKPKQKWKPFSQKQIILLEQSYQKHQISRDHGWIKLDNNFEVNFDKDPMEMRLPIRSPIK 3180
Query: 3181 RDFLSGIQIEFKQSSHQRSLRARLYWLQVDNQLPGAMFPVVFHPVAPPKSIALDSEPKPF 3240
RDFLSGIQIEFKQSSHQRSLRARLYWLQVDNQLPGAMFPVVFHPVAPPKSIALDSEPKPF
Sbjct: 3181 RDFLSGIQIEFKQSSHQRSLRARLYWLQVDNQLPGAMFPVVFHPVAPPKSIALDSEPKPF 3240
Query: 3241 IDVSVITRFNEYSKVLQFKYFMVLIQEMALKIDQGFLGAIIALFTPTTDPEAERRRTKLI 3300
IDVSVITRFNEYSKVLQFKYFMVLIQEMALKIDQGFLGAIIALFTPTTDPEAERRRTKLI
Sbjct: 3241 IDVSVITRFNEYSKVLQFKYFMVLIQEMALKIDQGFLGAIIALFTPTTDPEAERRRTKLI 3300
Query: 3301 QQDIDALNAELMETSMTDMSILSFFEHFHISPVKLHLSLSLGSGGEESDKEKQEMFAVHS 3360
QQDIDALNAELMETSMTDMSILSFFEHFHISPVKLHLSLSLGSGGEESDKEKQEMFAVHS
Sbjct: 3301 QQDIDALNAELMETSMTDMSILSFFEHFHISPVKLHLSLSLGSGGEESDKEKQEMFAVHS 3360
Query: 3361 VNLLLKSIGATLTDVDDLIFKLAYYEIRYQFYKRDQLIWSVVRHYSEQFLKQMYVLVLGL 3420
VNLLLKSIGATLTDVDDLIFKLAYYEIRYQFYKRDQLIWSVVRHYSEQFLKQMYVLVLGL
Sbjct: 3361 VNLLLKSIGATLTDVDDLIFKLAYYEIRYQFYKRDQLIWSVVRHYSEQFLKQMYVLVLGL 3420
Query: 3421 DVLGNPFGLIRGLSEGVEALFYEPFQGAVQGPEEFAEGLVIGVRSLFGHTVGGAAGVVSR 3480
DVLGNPFGLIRGLSEGVEALFYEPFQGAVQGPEEFAEGLVIGVRSLFGHTVGGAAGVVSR
Sbjct: 3421 DVLGNPFGLIRGLSEGVEALFYEPFQGAVQGPEEFAEGLVIGVRSLFGHTVGGAAGVVSR 3480
Query: 3481 ITGSVGKGLAAITMDKEYQQKRREELSRQPRDFGDSLARGGKGFLRGVVGGVTGIITKPV 3540
ITGSVGKGLAAITMDKEYQQKRREELSRQPRDFGDSLARGGKGFLRGVVGGVTGIITKPV
Sbjct: 3481 ITGSVGKGLAAITMDKEYQQKRREELSRQPRDFGDSLARGGKGFLRGVVGGVTGIITKPV 3540
Query: 3541 EGAKKEGAAGFFKGIGKGLVGAVARPTGGIVDMASSTFQGIQRAAESTEEVSSLRPPRLI 3600
EGAKKEGAAGFFKGIGKGLVGAVARPTGGIVDMASSTFQGIQRAAESTEEVSSLRPPRLI
Sbjct: 3541 EGAKKEGAAGFFKGIGKGLVGAVARPTGGIVDMASSTFQGIQRAAESTEEVSSLRPPRLI 3600
Query: 3601 HEDGIIRPYDRQESEGSDLLENHIKKLEGETYRYHCAIPGSKKTILMVTNRRVLCIKEVE 3660
HEDGIIRPYDRQESEGSDLLENHIKKLEGETYRYHCAIPGSKKTILMVTNRRVLCIKEVE
Sbjct: 3601 HEDGIIRPYDRQESEGSDLLENHIKKLEGETYRYHCAIPGSKKTILMVTNRRVLCIKEVE 3660
Query: 3661 ILGLMCVDWQCPFEDFVFPPSVSENVLKISVKEQGLFHKKDSANQGCVRKVYLKDTATAE 3720
ILGLMCVDWQCPFEDFVFPPSVSENVLKISVKEQGLFHKKDSANQGCVRKVYLKDTATAE
Sbjct: 3661 ILGLMCVDWQCPFEDFVFPPSVSENVLKISVKEQGLFHKKDSANQGCVRKVYLKDTATAE 3720
Query: 3721 RACNAIEDAQSTRQQQKLMKQSSVRLLRPQLPS 3753
RACNAIEDAQSTRQQQKLMKQSSVRLLRPQLPS
Sbjct: 3721 RACNAIEDAQSTRQQQKLMKQSSVRLLRPQLPS 3753
>gi|42544121 vacuolar protein sorting 13C protein isoform 1A [Homo
sapiens]
Length = 3710
Score = 7260 bits (18837), Expect = 0.0
Identities = 3710/3753 (98%), Positives = 3710/3753 (98%), Gaps = 43/3753 (1%)
Query: 1 MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAG 60
MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAG
Sbjct: 1 MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAG 60
Query: 61 QIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEE 120
QIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEE
Sbjct: 61 QIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEE 120
Query: 121 ALQKAAEKGTHSGEFIYGLENFVYKDIKPGRKRKKHKKHFKKPFKGLDRSKDKPKEAKKD 180
ALQKAAEK DKPKEAKKD
Sbjct: 121 ALQKAAEK-------------------------------------------DKPKEAKKD 137
Query: 181 TFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLGELSLLTANEHWTPCILN 240
TFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLGELSLLTANEHWTPCILN
Sbjct: 138 TFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLGELSLLTANEHWTPCILN 197
Query: 241 EADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILDQLKNEILTSGNIPPNYQYIFQPIS 300
EADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILDQLKNEILTSGNIPPNYQYIFQPIS
Sbjct: 198 EADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILDQLKNEILTSGNIPPNYQYIFQPIS 257
Query: 301 ASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKPQYLSMIDLLESVDYMVRNAPYRKY 360
ASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKPQYLSMIDLLESVDYMVRNAPYRKY
Sbjct: 258 ASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKPQYLSMIDLLESVDYMVRNAPYRKY 317
Query: 361 KPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIKKHRQLLKSYKIAYKNKLTQSK 420
KPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIKKHRQLLKSYKIAYKNKLTQSK
Sbjct: 318 KPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIKKHRQLLKSYKIAYKNKLTQSK 377
Query: 421 VSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKSADTGEKRGGWFSGLWGK 480
VSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKSADTGEKRGGWFSGLWGK
Sbjct: 378 VSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKSADTGEKRGGWFSGLWGK 437
Query: 481 KESKKKDEESLIPETIDDLMTPEEKDKLFTAIGYSESTHNLTLPKQYVAHIMTLKLVSTS 540
KESKKKDEESLIPETIDDLMTPEEKDKLFTAIGYSESTHNLTLPKQYVAHIMTLKLVSTS
Sbjct: 438 KESKKKDEESLIPETIDDLMTPEEKDKLFTAIGYSESTHNLTLPKQYVAHIMTLKLVSTS 497
Query: 541 VTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVEAKLEHWYITGLRQQDIVPSLVASI 600
VTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVEAKLEHWYITGLRQQDIVPSLVASI
Sbjct: 498 VTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVEAKLEHWYITGLRQQDIVPSLVASI 557
Query: 601 GDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIYDAKTVNAVVEFFQSNKGLDLEQIT 660
GDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIYDAKTVNAVVEFFQSNKGLDLEQIT
Sbjct: 558 GDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIYDAKTVNAVVEFFQSNKGLDLEQIT 617
Query: 661 SATLMKLEEIKERTATGLTHIIETRKVLDLRINLKPSYLVVPQTGFHHEKSDLLILDFGT 720
SATLMKLEEIKERTATGLTHIIETRKVLDLRINLKPSYLVVPQTGFHHEKSDLLILDFGT
Sbjct: 618 SATLMKLEEIKERTATGLTHIIETRKVLDLRINLKPSYLVVPQTGFHHEKSDLLILDFGT 677
Query: 721 FQLNSKDQGLQKTTNSSLEEIMDKAYDKFDVEIKNVQLLFARAEETWKKCRFQHPSTMHI 780
FQLNSKDQGLQKTTNSSLEEIMDKAYDKFDVEIKNVQLLFARAEETWKKCRFQHPSTMHI
Sbjct: 678 FQLNSKDQGLQKTTNSSLEEIMDKAYDKFDVEIKNVQLLFARAEETWKKCRFQHPSTMHI 737
Query: 781 LQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVRISDQKMKDVLYLMNSIPLPQKSSA 840
LQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVRISDQKMKDVLYLMNSIPLPQKSSA
Sbjct: 738 LQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVRISDQKMKDVLYLMNSIPLPQKSSA 797
Query: 841 QSPERQVSSIPIISGGTKGLLGTSLLLDTVESESDDEYFDAEDGEPQTCKSMKGSELKKA 900
QSPERQVSSIPIISGGTKGLLGTSLLLDTVESESDDEYFDAEDGEPQTCKSMKGSELKKA
Sbjct: 798 QSPERQVSSIPIISGGTKGLLGTSLLLDTVESESDDEYFDAEDGEPQTCKSMKGSELKKA 857
Query: 901 AEVPNEELINLLLKFEIKEVILEFTKQQKEEDTILVFNVTQLGTEATMRTFDLTVVSYLK 960
AEVPNEELINLLLKFEIKEVILEFTKQQKEEDTILVFNVTQLGTEATMRTFDLTVVSYLK
Sbjct: 858 AEVPNEELINLLLKFEIKEVILEFTKQQKEEDTILVFNVTQLGTEATMRTFDLTVVSYLK 917
Query: 961 KISLDYHEIEGSKRKPLHLISSSDKPGLDLLKVEYIKADKNGPSFQTAFGKTEQTVKVAF 1020
KISLDYHEIEGSKRKPLHLISSSDKPGLDLLKVEYIKADKNGPSFQTAFGKTEQTVKVAF
Sbjct: 918 KISLDYHEIEGSKRKPLHLISSSDKPGLDLLKVEYIKADKNGPSFQTAFGKTEQTVKVAF 977
Query: 1021 SSLNLLLQTQALVASINYLTTIIPSDDQSISVAKEVQISTEKQQKNSTLPKAIVSSRDSD 1080
SSLNLLLQTQALVASINYLTTIIPSDDQSISVAKEVQISTEKQQKNSTLPKAIVSSRDSD
Sbjct: 978 SSLNLLLQTQALVASINYLTTIIPSDDQSISVAKEVQISTEKQQKNSTLPKAIVSSRDSD 1037
Query: 1081 IIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSSLSLQSRKQSLFARLENIIVTDVDPK 1140
IIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSSLSLQSRKQSLFARLENIIVTDVDPK
Sbjct: 1038 IIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSSLSLQSRKQSLFARLENIIVTDVDPK 1097
Query: 1141 TVHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMSKVDGVLSLNVGCIQIVYLHKFLMSL 1200
TVHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMSKVDGVLSLNVGCIQIVYLHKFLMSL
Sbjct: 1098 TVHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMSKVDGVLSLNVGCIQIVYLHKFLMSL 1157
Query: 1201 LNFLNNFQTAKESLSAATAQAAERAATSVKDLAQRSFRVSINIDLKAPVIVIPQSSISTN 1260
LNFLNNFQTAKESLSAATAQAAERAATSVKDLAQRSFRVSINIDLKAPVIVIPQSSISTN
Sbjct: 1158 LNFLNNFQTAKESLSAATAQAAERAATSVKDLAQRSFRVSINIDLKAPVIVIPQSSISTN 1217
Query: 1261 AVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQLTKLTLYRTVIQPGIYHPDIQLLHP 1320
AVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQLTKLTLYRTVIQPGIYHPDIQLLHP
Sbjct: 1218 AVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQLTKLTLYRTVIQPGIYHPDIQLLHP 1277
Query: 1321 INLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLNQEDLNLLFRILTENLCEGTEDLDK 1380
INLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLNQEDLNLLFRILTENLCEGTEDLDK
Sbjct: 1278 INLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLNQEDLNLLFRILTENLCEGTEDLDK 1337
Query: 1381 VKPRVQETGEIKEPLEISISQDVHDSKNTLTTGVEEIRSVDIINMLLNFEIKEVVVTLMK 1440
VKPRVQETGEIKEPLEISISQDVHDSKNTLTTGVEEIRSVDIINMLLNFEIKEVVVTLMK
Sbjct: 1338 VKPRVQETGEIKEPLEISISQDVHDSKNTLTTGVEEIRSVDIINMLLNFEIKEVVVTLMK 1397
Query: 1441 KSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFDFTDSKGEPLHIINSSNV 1500
KSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFDFTDSKGEPLHIINSSNV
Sbjct: 1398 KSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFDFTDSKGEPLHIINSSNV 1457
Query: 1501 TDEPLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLHLEALLSFMDFLSSAAPF 1560
TDEPLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLHLEALLSFMDFLSSAAPF
Sbjct: 1458 TDEPLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLHLEALLSFMDFLSSAAPF 1517
Query: 1561 SEPSSSEKESELKPLVGESRSIAVKAVSSNISQKDVFDLKITAELNAFNVFVCDQKCNIA 1620
SEPSSSEKESELKPLVGESRSIAVKAVSSNISQKDVFDLKITAELNAFNVFVCDQKCNIA
Sbjct: 1518 SEPSSSEKESELKPLVGESRSIAVKAVSSNISQKDVFDLKITAELNAFNVFVCDQKCNIA 1577
Query: 1621 DIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQSIHKKAVSILGDEVFRFQLTLYPDA 1680
DIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQSIHKKAVSILGDEVFRFQLTLYPDA
Sbjct: 1578 DIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQSIHKKAVSILGDEVFRFQLTLYPDA 1637
Query: 1681 TEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQTAKEALSTATVQAAERA 1740
TEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQTAKEALSTATVQAAERA
Sbjct: 1638 TEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQTAKEALSTATVQAAERA 1697
Query: 1741 ASSMKDLAQKSFRLLMDINLKAPVIIIPQSSVSPNAVIADLGLIRVENKFSLVPMEHYSL 1800
ASSMKDLAQKSFRLLMDINLKAPVIIIPQSSVSPNAVIADLGLIRVENKFSLVPMEHYSL
Sbjct: 1698 ASSMKDLAQKSFRLLMDINLKAPVIIIPQSSVSPNAVIADLGLIRVENKFSLVPMEHYSL 1757
Query: 1801 PPVIDKMNIELTQLKLSRTILQASLPQNDIEILKPVNMLLSIQRNLAAAWYVQIPGMEIK 1860
PPVIDKMNIELTQLKLSRTILQASLPQNDIEILKPVNMLLSIQRNLAAAWYVQIPGMEIK
Sbjct: 1758 PPVIDKMNIELTQLKLSRTILQASLPQNDIEILKPVNMLLSIQRNLAAAWYVQIPGMEIK 1817
Query: 1861 GKLKPMQVALSEDDLTVLMKILLENLGEASSQPSPTQSVQETVRVRKVDVSSVPDHLKEQ 1920
GKLKPMQVALSEDDLTVLMKILLENLGEASSQPSPTQSVQETVRVRKVDVSSVPDHLKEQ
Sbjct: 1818 GKLKPMQVALSEDDLTVLMKILLENLGEASSQPSPTQSVQETVRVRKVDVSSVPDHLKEQ 1877
Query: 1921 EDWTDSKLSMNQIVSLQFDFHFESLSIILYNNDINQESGVAFHNDSFQLGELRLHLMASS 1980
EDWTDSKLSMNQIVSLQFDFHFESLSIILYNNDINQESGVAFHNDSFQLGELRLHLMASS
Sbjct: 1878 EDWTDSKLSMNQIVSLQFDFHFESLSIILYNNDINQESGVAFHNDSFQLGELRLHLMASS 1937
Query: 1981 GKMFKDGSMNVSVKLKTCTLDDLREGIERATSRMIDRKNDQDNNSSMIDISYKQDKNGSQ 2040
GKMFKDGSMNVSVKLKTCTLDDLREGIERATSRMIDRKNDQDNNSSMIDISYKQDKNGSQ
Sbjct: 1938 GKMFKDGSMNVSVKLKTCTLDDLREGIERATSRMIDRKNDQDNNSSMIDISYKQDKNGSQ 1997
Query: 2041 IDAVLDKLYVCASVEFLMTVADFFIKAVPQSPENVAKETQILPRQTATGKVKIEKDDSVR 2100
IDAVLDKLYVCASVEFLMTVADFFIKAVPQSPENVAKETQILPRQTATGKVKIEKDDSVR
Sbjct: 1998 IDAVLDKLYVCASVEFLMTVADFFIKAVPQSPENVAKETQILPRQTATGKVKIEKDDSVR 2057
Query: 2101 PNMTLKAMITDPEVVFVASLTKADAPALTASFQCNLSLSTSKLEQMMEASVRDLKVLACP 2160
PNMTLKAMITDPEVVFVASLTKADAPALTASFQCNLSLSTSKLEQMMEASVRDLKVLACP
Sbjct: 2058 PNMTLKAMITDPEVVFVASLTKADAPALTASFQCNLSLSTSKLEQMMEASVRDLKVLACP 2117
Query: 2161 FLREKRGKNITTVLQPCSLFMEKCTWASGKQNINIMVKEFIIKISPIILNTVLTIMAALS 2220
FLREKRGKNITTVLQPCSLFMEKCTWASGKQNINIMVKEFIIKISPIILNTVLTIMAALS
Sbjct: 2118 FLREKRGKNITTVLQPCSLFMEKCTWASGKQNINIMVKEFIIKISPIILNTVLTIMAALS 2177
Query: 2221 PKTKEDGSKDTSKEMENLWGIKSINDYNTWFLGVDTATEITESFKGIEHSLIEENCGVVV 2280
PKTKEDGSKDTSKEMENLWGIKSINDYNTWFLGVDTATEITESFKGIEHSLIEENCGVVV
Sbjct: 2178 PKTKEDGSKDTSKEMENLWGIKSINDYNTWFLGVDTATEITESFKGIEHSLIEENCGVVV 2237
Query: 2281 ESIQVTLECGLGHRTVPLLLAESKFSGNIKNWTSLMAAVADVTLQVHYYNEIHAVWEPLI 2340
ESIQVTLECGLGHRTVPLLLAESKFSGNIKNWTSLMAAVADVTLQVHYYNEIHAVWEPLI
Sbjct: 2238 ESIQVTLECGLGHRTVPLLLAESKFSGNIKNWTSLMAAVADVTLQVHYYNEIHAVWEPLI 2297
Query: 2341 ERVEGKRQWNLRLDVKKNPVQDKSLLPGDDFIPEPQMAIHISSGNTMNITISKSCLNVFN 2400
ERVEGKRQWNLRLDVKKNPVQDKSLLPGDDFIPEPQMAIHISSGNTMNITISKSCLNVFN
Sbjct: 2298 ERVEGKRQWNLRLDVKKNPVQDKSLLPGDDFIPEPQMAIHISSGNTMNITISKSCLNVFN 2357
Query: 2401 NLAKGFSEGTASTFDYSLKDRAPFTVKNAVGVPIKVKPNCNLRVMGFPEKSDIFDVDAGQ 2460
NLAKGFSEGTASTFDYSLKDRAPFTVKNAVGVPIKVKPNCNLRVMGFPEKSDIFDVDAGQ
Sbjct: 2358 NLAKGFSEGTASTFDYSLKDRAPFTVKNAVGVPIKVKPNCNLRVMGFPEKSDIFDVDAGQ 2417
Query: 2461 NLELEYASMVPSSQGNLSILSRQESSFFTLTIVPHGYTEVANIPVARPGRRLYNVRNPNA 2520
NLELEYASMVPSSQGNLSILSRQESSFFTLTIVPHGYTEVANIPVARPGRRLYNVRNPNA
Sbjct: 2418 NLELEYASMVPSSQGNLSILSRQESSFFTLTIVPHGYTEVANIPVARPGRRLYNVRNPNA 2477
Query: 2521 SHSDSVLVQIDATEGNKVITLRSPLQIKNHFSIAFIIYKFVKNVKLLERIGIARPEEEFH 2580
SHSDSVLVQIDATEGNKVITLRSPLQIKNHFSIAFIIYKFVKNVKLLERIGIARPEEEFH
Sbjct: 2478 SHSDSVLVQIDATEGNKVITLRSPLQIKNHFSIAFIIYKFVKNVKLLERIGIARPEEEFH 2537
Query: 2581 VPLDSYRCQLFIQPAGILEHQYKESTTYISWKEELHRSREVRCMLQCPSVEVSFLPLIVN 2640
VPLDSYRCQLFIQPAGILEHQYKESTTYISWKEELHRSREVRCMLQCPSVEVSFLPLIVN
Sbjct: 2538 VPLDSYRCQLFIQPAGILEHQYKESTTYISWKEELHRSREVRCMLQCPSVEVSFLPLIVN 2597
Query: 2641 TVALPDELSYICTHGEDWDVAYIIHLYPSLTLRNLLPYSLRYLLEGTAETHELAEGSTAD 2700
TVALPDELSYICTHGEDWDVAYIIHLYPSLTLRNLLPYSLRYLLEGTAETHELAEGSTAD
Sbjct: 2598 TVALPDELSYICTHGEDWDVAYIIHLYPSLTLRNLLPYSLRYLLEGTAETHELAEGSTAD 2657
Query: 2701 VLHSRISGEIMELVLVKYQGKNWNGHFRIRDTLPEFFPVCFSSDSTEVTTVDLSVHVRRI 2760
VLHSRISGEIMELVLVKYQGKNWNGHFRIRDTLPEFFPVCFSSDSTEVTTVDLSVHVRRI
Sbjct: 2658 VLHSRISGEIMELVLVKYQGKNWNGHFRIRDTLPEFFPVCFSSDSTEVTTVDLSVHVRRI 2717
Query: 2761 GSRMVLSVFSPYWLINKTTRVLQYRSEDIHVKHPADFRDIILFSFKKKNIFTKNKVQLKI 2820
GSRMVLSVFSPYWLINKTTRVLQYRSEDIHVKHPADFRDIILFSFKKKNIFTKNKVQLKI
Sbjct: 2718 GSRMVLSVFSPYWLINKTTRVLQYRSEDIHVKHPADFRDIILFSFKKKNIFTKNKVQLKI 2777
Query: 2821 STSAWSSSFSLDTVGSYGCVKCPANNMEYLVGVSIKMSSFNLSRIVTLTPFCTIANKSSL 2880
STSAWSSSFSLDTVGSYGCVKCPANNMEYLVGVSIKMSSFNLSRIVTLTPFCTIANKSSL
Sbjct: 2778 STSAWSSSFSLDTVGSYGCVKCPANNMEYLVGVSIKMSSFNLSRIVTLTPFCTIANKSSL 2837
Query: 2881 ELEVGEIASDGSMPTNKWNYIASSECLPFWPESLSGKLCVRVVGCEGSSKPFFYNRQDNG 2940
ELEVGEIASDGSMPTNKWNYIASSECLPFWPESLSGKLCVRVVGCEGSSKPFFYNRQDNG
Sbjct: 2838 ELEVGEIASDGSMPTNKWNYIASSECLPFWPESLSGKLCVRVVGCEGSSKPFFYNRQDNG 2897
Query: 2941 TLLSLEDLNGGILVDVNTAEHSTVITFSDYHEGSAPALIMNHTPWDILTYKQSGSPEEMV 3000
TLLSLEDLNGGILVDVNTAEHSTVITFSDYHEGSAPALIMNHTPWDILTYKQSGSPEEMV
Sbjct: 2898 TLLSLEDLNGGILVDVNTAEHSTVITFSDYHEGSAPALIMNHTPWDILTYKQSGSPEEMV 2957
Query: 3001 LLPRQARLFAWADPTGTRKLTWTYAANVGEHDLLKDGCGQFPYDANIQIHWVSFLDGRQR 3060
LLPRQARLFAWADPTGTRKLTWTYAANVGEHDLLKDGCGQFPYDANIQIHWVSFLDGRQR
Sbjct: 2958 LLPRQARLFAWADPTGTRKLTWTYAANVGEHDLLKDGCGQFPYDANIQIHWVSFLDGRQR 3017
Query: 3061 VLLFTDDVALVSKALQAEEMEQADYEITLSLHSLGLSLVNNESKQEVSYIGITSSGVVWE 3120
VLLFTDDVALVSKALQAEEMEQADYEITLSLHSLGLSLVNNESKQEVSYIGITSSGVVWE
Sbjct: 3018 VLLFTDDVALVSKALQAEEMEQADYEITLSLHSLGLSLVNNESKQEVSYIGITSSGVVWE 3077
Query: 3121 VKPKQKWKPFSQKQIILLEQSYQKHQISRDHGWIKLDNNFEVNFDKDPMEMRLPIRSPIK 3180
VKPKQKWKPFSQKQIILLEQSYQKHQISRDHGWIKLDNNFEVNFDKDPMEMRLPIRSPIK
Sbjct: 3078 VKPKQKWKPFSQKQIILLEQSYQKHQISRDHGWIKLDNNFEVNFDKDPMEMRLPIRSPIK 3137
Query: 3181 RDFLSGIQIEFKQSSHQRSLRARLYWLQVDNQLPGAMFPVVFHPVAPPKSIALDSEPKPF 3240
RDFLSGIQIEFKQSSHQRSLRARLYWLQVDNQLPGAMFPVVFHPVAPPKSIALDSEPKPF
Sbjct: 3138 RDFLSGIQIEFKQSSHQRSLRARLYWLQVDNQLPGAMFPVVFHPVAPPKSIALDSEPKPF 3197
Query: 3241 IDVSVITRFNEYSKVLQFKYFMVLIQEMALKIDQGFLGAIIALFTPTTDPEAERRRTKLI 3300
IDVSVITRFNEYSKVLQFKYFMVLIQEMALKIDQGFLGAIIALFTPTTDPEAERRRTKLI
Sbjct: 3198 IDVSVITRFNEYSKVLQFKYFMVLIQEMALKIDQGFLGAIIALFTPTTDPEAERRRTKLI 3257
Query: 3301 QQDIDALNAELMETSMTDMSILSFFEHFHISPVKLHLSLSLGSGGEESDKEKQEMFAVHS 3360
QQDIDALNAELMETSMTDMSILSFFEHFHISPVKLHLSLSLGSGGEESDKEKQEMFAVHS
Sbjct: 3258 QQDIDALNAELMETSMTDMSILSFFEHFHISPVKLHLSLSLGSGGEESDKEKQEMFAVHS 3317
Query: 3361 VNLLLKSIGATLTDVDDLIFKLAYYEIRYQFYKRDQLIWSVVRHYSEQFLKQMYVLVLGL 3420
VNLLLKSIGATLTDVDDLIFKLAYYEIRYQFYKRDQLIWSVVRHYSEQFLKQMYVLVLGL
Sbjct: 3318 VNLLLKSIGATLTDVDDLIFKLAYYEIRYQFYKRDQLIWSVVRHYSEQFLKQMYVLVLGL 3377
Query: 3421 DVLGNPFGLIRGLSEGVEALFYEPFQGAVQGPEEFAEGLVIGVRSLFGHTVGGAAGVVSR 3480
DVLGNPFGLIRGLSEGVEALFYEPFQGAVQGPEEFAEGLVIGVRSLFGHTVGGAAGVVSR
Sbjct: 3378 DVLGNPFGLIRGLSEGVEALFYEPFQGAVQGPEEFAEGLVIGVRSLFGHTVGGAAGVVSR 3437
Query: 3481 ITGSVGKGLAAITMDKEYQQKRREELSRQPRDFGDSLARGGKGFLRGVVGGVTGIITKPV 3540
ITGSVGKGLAAITMDKEYQQKRREELSRQPRDFGDSLARGGKGFLRGVVGGVTGIITKPV
Sbjct: 3438 ITGSVGKGLAAITMDKEYQQKRREELSRQPRDFGDSLARGGKGFLRGVVGGVTGIITKPV 3497
Query: 3541 EGAKKEGAAGFFKGIGKGLVGAVARPTGGIVDMASSTFQGIQRAAESTEEVSSLRPPRLI 3600
EGAKKEGAAGFFKGIGKGLVGAVARPTGGIVDMASSTFQGIQRAAESTEEVSSLRPPRLI
Sbjct: 3498 EGAKKEGAAGFFKGIGKGLVGAVARPTGGIVDMASSTFQGIQRAAESTEEVSSLRPPRLI 3557
Query: 3601 HEDGIIRPYDRQESEGSDLLENHIKKLEGETYRYHCAIPGSKKTILMVTNRRVLCIKEVE 3660
HEDGIIRPYDRQESEGSDLLENHIKKLEGETYRYHCAIPGSKKTILMVTNRRVLCIKEVE
Sbjct: 3558 HEDGIIRPYDRQESEGSDLLENHIKKLEGETYRYHCAIPGSKKTILMVTNRRVLCIKEVE 3617
Query: 3661 ILGLMCVDWQCPFEDFVFPPSVSENVLKISVKEQGLFHKKDSANQGCVRKVYLKDTATAE 3720
ILGLMCVDWQCPFEDFVFPPSVSENVLKISVKEQGLFHKKDSANQGCVRKVYLKDTATAE
Sbjct: 3618 ILGLMCVDWQCPFEDFVFPPSVSENVLKISVKEQGLFHKKDSANQGCVRKVYLKDTATAE 3677
Query: 3721 RACNAIEDAQSTRQQQKLMKQSSVRLLRPQLPS 3753
RACNAIEDAQSTRQQQKLMKQSSVRLLRPQLPS
Sbjct: 3678 RACNAIEDAQSTRQQQKLMKQSSVRLLRPQLPS 3710
>gi|66347845 vacuolar protein sorting 13C protein isoform 2B [Homo
sapiens]
Length = 3628
Score = 7108 bits (18441), Expect = 0.0
Identities = 3621/3625 (99%), Positives = 3623/3625 (99%)
Query: 1 MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAG 60
MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAG
Sbjct: 1 MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAG 60
Query: 61 QIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEE 120
QIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEE
Sbjct: 61 QIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEE 120
Query: 121 ALQKAAEKGTHSGEFIYGLENFVYKDIKPGRKRKKHKKHFKKPFKGLDRSKDKPKEAKKD 180
ALQKAAEKGTHSGEFIYGLENFVYKDIKPGRKRKKHKKHFKKPFKGLDRSKDKPKEAKKD
Sbjct: 121 ALQKAAEKGTHSGEFIYGLENFVYKDIKPGRKRKKHKKHFKKPFKGLDRSKDKPKEAKKD 180
Query: 181 TFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLGELSLLTANEHWTPCILN 240
TFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLGELSLLTANEHWTPCILN
Sbjct: 181 TFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLGELSLLTANEHWTPCILN 240
Query: 241 EADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILDQLKNEILTSGNIPPNYQYIFQPIS 300
EADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILDQLKNEILTSGNIPPNYQYIFQPIS
Sbjct: 241 EADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILDQLKNEILTSGNIPPNYQYIFQPIS 300
Query: 301 ASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKPQYLSMIDLLESVDYMVRNAPYRKY 360
ASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKPQYLSMIDLLESVDYMVRNAPYRKY
Sbjct: 301 ASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKPQYLSMIDLLESVDYMVRNAPYRKY 360
Query: 361 KPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIKKHRQLLKSYKIAYKNKLTQSK 420
KPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIKKHRQLLKSYKIAYKNKLTQSK
Sbjct: 361 KPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIKKHRQLLKSYKIAYKNKLTQSK 420
Query: 421 VSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKSADTGEKRGGWFSGLWGK 480
VSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKSADTGEKRGGWFSGLWGK
Sbjct: 421 VSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKSADTGEKRGGWFSGLWGK 480
Query: 481 KESKKKDEESLIPETIDDLMTPEEKDKLFTAIGYSESTHNLTLPKQYVAHIMTLKLVSTS 540
KESKKKDEESLIPETIDDLMTPEEKDKLFTAIGYSESTHNLTLPKQYVAHIMTLKLVSTS
Sbjct: 481 KESKKKDEESLIPETIDDLMTPEEKDKLFTAIGYSESTHNLTLPKQYVAHIMTLKLVSTS 540
Query: 541 VTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVEAKLEHWYITGLRQQDIVPSLVASI 600
VTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVEAKLEHWYITGLRQQDIVPSLVASI
Sbjct: 541 VTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVEAKLEHWYITGLRQQDIVPSLVASI 600
Query: 601 GDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIYDAKTVNAVVEFFQSNKGLDLEQIT 660
GDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIYDAKTVNAVVEFFQSNKGLDLEQIT
Sbjct: 601 GDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIYDAKTVNAVVEFFQSNKGLDLEQIT 660
Query: 661 SATLMKLEEIKERTATGLTHIIETRKVLDLRINLKPSYLVVPQTGFHHEKSDLLILDFGT 720
SATLMKLEEIKERTATGLTHIIETRKVLDLRINLKPSYLVVPQTGFHHEKSDLLILDFGT
Sbjct: 661 SATLMKLEEIKERTATGLTHIIETRKVLDLRINLKPSYLVVPQTGFHHEKSDLLILDFGT 720
Query: 721 FQLNSKDQGLQKTTNSSLEEIMDKAYDKFDVEIKNVQLLFARAEETWKKCRFQHPSTMHI 780
FQLNSKDQGLQKTTNSSLEEIMDKAYDKFDVEIKNVQLLFARAEETWKKCRFQHPSTMHI
Sbjct: 721 FQLNSKDQGLQKTTNSSLEEIMDKAYDKFDVEIKNVQLLFARAEETWKKCRFQHPSTMHI 780
Query: 781 LQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVRISDQKMKDVLYLMNSIPLPQKSSA 840
LQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVRISDQKMKDVLYLMNSIPLPQKSSA
Sbjct: 781 LQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVRISDQKMKDVLYLMNSIPLPQKSSA 840
Query: 841 QSPERQVSSIPIISGGTKGLLGTSLLLDTVESESDDEYFDAEDGEPQTCKSMKGSELKKA 900
QSPERQVSSIPIISGGTKGLLGTSLLLDTVESESDDEYFDAEDGEPQTCKSMKGSELKKA
Sbjct: 841 QSPERQVSSIPIISGGTKGLLGTSLLLDTVESESDDEYFDAEDGEPQTCKSMKGSELKKA 900
Query: 901 AEVPNEELINLLLKFEIKEVILEFTKQQKEEDTILVFNVTQLGTEATMRTFDLTVVSYLK 960
AEVPNEELINLLLKFEIKEVILEFTKQQKEEDTILVFNVTQLGTEATMRTFDLTVVSYLK
Sbjct: 901 AEVPNEELINLLLKFEIKEVILEFTKQQKEEDTILVFNVTQLGTEATMRTFDLTVVSYLK 960
Query: 961 KISLDYHEIEGSKRKPLHLISSSDKPGLDLLKVEYIKADKNGPSFQTAFGKTEQTVKVAF 1020
KISLDYHEIEGSKRKPLHLISSSDKPGLDLLKVEYIKADKNGPSFQTAFGKTEQTVKVAF
Sbjct: 961 KISLDYHEIEGSKRKPLHLISSSDKPGLDLLKVEYIKADKNGPSFQTAFGKTEQTVKVAF 1020
Query: 1021 SSLNLLLQTQALVASINYLTTIIPSDDQSISVAKEVQISTEKQQKNSTLPKAIVSSRDSD 1080
SSLNLLLQTQALVASINYLTTIIPSDDQSISVAKEVQISTEKQQKNSTLPKAIVSSRDSD
Sbjct: 1021 SSLNLLLQTQALVASINYLTTIIPSDDQSISVAKEVQISTEKQQKNSTLPKAIVSSRDSD 1080
Query: 1081 IIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSSLSLQSRKQSLFARLENIIVTDVDPK 1140
IIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSSLSLQSRKQSLFARLENIIVTDVDPK
Sbjct: 1081 IIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSSLSLQSRKQSLFARLENIIVTDVDPK 1140
Query: 1141 TVHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMSKVDGVLSLNVGCIQIVYLHKFLMSL 1200
TVHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMSKVDGVLSLNVGCIQIVYLHKFLMSL
Sbjct: 1141 TVHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMSKVDGVLSLNVGCIQIVYLHKFLMSL 1200
Query: 1201 LNFLNNFQTAKESLSAATAQAAERAATSVKDLAQRSFRVSINIDLKAPVIVIPQSSISTN 1260
LNFLNNFQTAKESLSAATAQAAERAATSVKDLAQRSFRVSINIDLKAPVIVIPQSSISTN
Sbjct: 1201 LNFLNNFQTAKESLSAATAQAAERAATSVKDLAQRSFRVSINIDLKAPVIVIPQSSISTN 1260
Query: 1261 AVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQLTKLTLYRTVIQPGIYHPDIQLLHP 1320
AVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQLTKLTLYRTVIQPGIYHPDIQLLHP
Sbjct: 1261 AVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQLTKLTLYRTVIQPGIYHPDIQLLHP 1320
Query: 1321 INLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLNQEDLNLLFRILTENLCEGTEDLDK 1380
INLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLNQEDLNLLFRILTENLCEGTEDLDK
Sbjct: 1321 INLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLNQEDLNLLFRILTENLCEGTEDLDK 1380
Query: 1381 VKPRVQETGEIKEPLEISISQDVHDSKNTLTTGVEEIRSVDIINMLLNFEIKEVVVTLMK 1440
VKPRVQETGEIKEPLEISISQDVHDSKNTLTTGVEEIRSVDIINMLLNFEIKEVVVTLMK
Sbjct: 1381 VKPRVQETGEIKEPLEISISQDVHDSKNTLTTGVEEIRSVDIINMLLNFEIKEVVVTLMK 1440
Query: 1441 KSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFDFTDSKGEPLHIINSSNV 1500
KSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFDFTDSKGEPLHIINSSNV
Sbjct: 1441 KSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFDFTDSKGEPLHIINSSNV 1500
Query: 1501 TDEPLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLHLEALLSFMDFLSSAAPF 1560
TDEPLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLHLEALLSFMDFLSSAAPF
Sbjct: 1501 TDEPLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLHLEALLSFMDFLSSAAPF 1560
Query: 1561 SEPSSSEKESELKPLVGESRSIAVKAVSSNISQKDVFDLKITAELNAFNVFVCDQKCNIA 1620
SEPSSSEKESELKPLVGESRSIAVKAVSSNISQKDVFDLKITAELNAFNVFVCDQKCNIA
Sbjct: 1561 SEPSSSEKESELKPLVGESRSIAVKAVSSNISQKDVFDLKITAELNAFNVFVCDQKCNIA 1620
Query: 1621 DIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQSIHKKAVSILGDEVFRFQLTLYPDA 1680
DIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQSIHKKAVSILGDEVFRFQLTLYPDA
Sbjct: 1621 DIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQSIHKKAVSILGDEVFRFQLTLYPDA 1680
Query: 1681 TEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQTAKEALSTATVQAAERA 1740
TEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQTAKEALSTATVQAAERA
Sbjct: 1681 TEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQTAKEALSTATVQAAERA 1740
Query: 1741 ASSMKDLAQKSFRLLMDINLKAPVIIIPQSSVSPNAVIADLGLIRVENKFSLVPMEHYSL 1800
ASSMKDLAQKSFRLLMDINLKAPVIIIPQSSVSPNAVIADLGLIRVENKFSLVPMEHYSL
Sbjct: 1741 ASSMKDLAQKSFRLLMDINLKAPVIIIPQSSVSPNAVIADLGLIRVENKFSLVPMEHYSL 1800
Query: 1801 PPVIDKMNIELTQLKLSRTILQASLPQNDIEILKPVNMLLSIQRNLAAAWYVQIPGMEIK 1860
PPVIDKMNIELTQLKLSRTILQASLPQNDIEILKPVNMLLSIQRNLAAAWYVQIPGMEIK
Sbjct: 1801 PPVIDKMNIELTQLKLSRTILQASLPQNDIEILKPVNMLLSIQRNLAAAWYVQIPGMEIK 1860
Query: 1861 GKLKPMQVALSEDDLTVLMKILLENLGEASSQPSPTQSVQETVRVRKVDVSSVPDHLKEQ 1920
GKLKPMQVALSEDDLTVLMKILLENLGEASSQPSPTQSVQETVRVRKVDVSSVPDHLKEQ
Sbjct: 1861 GKLKPMQVALSEDDLTVLMKILLENLGEASSQPSPTQSVQETVRVRKVDVSSVPDHLKEQ 1920
Query: 1921 EDWTDSKLSMNQIVSLQFDFHFESLSIILYNNDINQESGVAFHNDSFQLGELRLHLMASS 1980
EDWTDSKLSMNQIVSLQFDFHFESLSIILYNNDINQESGVAFHNDSFQLGELRLHLMASS
Sbjct: 1921 EDWTDSKLSMNQIVSLQFDFHFESLSIILYNNDINQESGVAFHNDSFQLGELRLHLMASS 1980
Query: 1981 GKMFKDGSMNVSVKLKTCTLDDLREGIERATSRMIDRKNDQDNNSSMIDISYKQDKNGSQ 2040
GKMFKDGSMNVSVKLKTCTLDDLREGIERATSRMIDRKNDQDNNSSMIDISYKQDKNGSQ
Sbjct: 1981 GKMFKDGSMNVSVKLKTCTLDDLREGIERATSRMIDRKNDQDNNSSMIDISYKQDKNGSQ 2040
Query: 2041 IDAVLDKLYVCASVEFLMTVADFFIKAVPQSPENVAKETQILPRQTATGKVKIEKDDSVR 2100
IDAVLDKLYVCASVEFLMTVADFFIKAVPQSPENVAKETQILPRQTATGKVKIEKDDSVR
Sbjct: 2041 IDAVLDKLYVCASVEFLMTVADFFIKAVPQSPENVAKETQILPRQTATGKVKIEKDDSVR 2100
Query: 2101 PNMTLKAMITDPEVVFVASLTKADAPALTASFQCNLSLSTSKLEQMMEASVRDLKVLACP 2160
PNMTLKAMITDPEVVFVASLTKADAPALTASFQCNLSLSTSKLEQMMEASVRDLKVLACP
Sbjct: 2101 PNMTLKAMITDPEVVFVASLTKADAPALTASFQCNLSLSTSKLEQMMEASVRDLKVLACP 2160
Query: 2161 FLREKRGKNITTVLQPCSLFMEKCTWASGKQNINIMVKEFIIKISPIILNTVLTIMAALS 2220
FLREKRGKNITTVLQPCSLFMEKCTWASGKQNINIMVKEFIIKISPIILNTVLTIMAALS
Sbjct: 2161 FLREKRGKNITTVLQPCSLFMEKCTWASGKQNINIMVKEFIIKISPIILNTVLTIMAALS 2220
Query: 2221 PKTKEDGSKDTSKEMENLWGIKSINDYNTWFLGVDTATEITESFKGIEHSLIEENCGVVV 2280
PKTKEDGSKDTSKEMENLWGIKSINDYNTWFLGVDTATEITESFKGIEHSLIEENCGVVV
Sbjct: 2221 PKTKEDGSKDTSKEMENLWGIKSINDYNTWFLGVDTATEITESFKGIEHSLIEENCGVVV 2280
Query: 2281 ESIQVTLECGLGHRTVPLLLAESKFSGNIKNWTSLMAAVADVTLQVHYYNEIHAVWEPLI 2340
ESIQVTLECGLGHRTVPLLLAESKFSGNIKNWTSLMAAVADVTLQVHYYNEIHAVWEPLI
Sbjct: 2281 ESIQVTLECGLGHRTVPLLLAESKFSGNIKNWTSLMAAVADVTLQVHYYNEIHAVWEPLI 2340
Query: 2341 ERVEGKRQWNLRLDVKKNPVQDKSLLPGDDFIPEPQMAIHISSGNTMNITISKSCLNVFN 2400
ERVEGKRQWNLRLDVKKNPVQDKSLLPGDDFIPEPQMAIHISSGNTMNITISKSCLNVFN
Sbjct: 2341 ERVEGKRQWNLRLDVKKNPVQDKSLLPGDDFIPEPQMAIHISSGNTMNITISKSCLNVFN 2400
Query: 2401 NLAKGFSEGTASTFDYSLKDRAPFTVKNAVGVPIKVKPNCNLRVMGFPEKSDIFDVDAGQ 2460
NLAKGFSEGTASTFDYSLKDRAPFTVKNAVGVPIKVKPNCNLRVMGFPEKSDIFDVDAGQ
Sbjct: 2401 NLAKGFSEGTASTFDYSLKDRAPFTVKNAVGVPIKVKPNCNLRVMGFPEKSDIFDVDAGQ 2460
Query: 2461 NLELEYASMVPSSQGNLSILSRQESSFFTLTIVPHGYTEVANIPVARPGRRLYNVRNPNA 2520
NLELEYASMVPSSQGNLSILSRQESSFFTLTIVPHGYTEVANIPVARPGRRLYNVRNPNA
Sbjct: 2461 NLELEYASMVPSSQGNLSILSRQESSFFTLTIVPHGYTEVANIPVARPGRRLYNVRNPNA 2520
Query: 2521 SHSDSVLVQIDATEGNKVITLRSPLQIKNHFSIAFIIYKFVKNVKLLERIGIARPEEEFH 2580
SHSDSVLVQIDATEGNKVITLRSPLQIKNHFSIAFIIYKFVKNVKLLERIGIARPEEEFH
Sbjct: 2521 SHSDSVLVQIDATEGNKVITLRSPLQIKNHFSIAFIIYKFVKNVKLLERIGIARPEEEFH 2580
Query: 2581 VPLDSYRCQLFIQPAGILEHQYKESTTYISWKEELHRSREVRCMLQCPSVEVSFLPLIVN 2640
VPLDSYRCQLFIQPAGILEHQYKESTTYISWKEELHRSREVRCMLQCPSVEVSFLPLIVN
Sbjct: 2581 VPLDSYRCQLFIQPAGILEHQYKESTTYISWKEELHRSREVRCMLQCPSVEVSFLPLIVN 2640
Query: 2641 TVALPDELSYICTHGEDWDVAYIIHLYPSLTLRNLLPYSLRYLLEGTAETHELAEGSTAD 2700
TVALPDELSYICTHGEDWDVAYIIHLYPSLTLRNLLPYSLRYLLEGTAETHELAEGSTAD
Sbjct: 2641 TVALPDELSYICTHGEDWDVAYIIHLYPSLTLRNLLPYSLRYLLEGTAETHELAEGSTAD 2700
Query: 2701 VLHSRISGEIMELVLVKYQGKNWNGHFRIRDTLPEFFPVCFSSDSTEVTTVDLSVHVRRI 2760
VLHSRISGEIMELVLVKYQGKNWNGHFRIRDTLPEFFPVCFSSDSTEVTTVDLSVHVRRI
Sbjct: 2701 VLHSRISGEIMELVLVKYQGKNWNGHFRIRDTLPEFFPVCFSSDSTEVTTVDLSVHVRRI 2760
Query: 2761 GSRMVLSVFSPYWLINKTTRVLQYRSEDIHVKHPADFRDIILFSFKKKNIFTKNKVQLKI 2820
GSRMVLSVFSPYWLINKTTRVLQYRSEDIHVKHPADFRDIILFSFKKKNIFTKNKVQLKI
Sbjct: 2761 GSRMVLSVFSPYWLINKTTRVLQYRSEDIHVKHPADFRDIILFSFKKKNIFTKNKVQLKI 2820
Query: 2821 STSAWSSSFSLDTVGSYGCVKCPANNMEYLVGVSIKMSSFNLSRIVTLTPFCTIANKSSL 2880
STSAWSSSFSLDTVGSYGCVKCPANNMEYLVGVSIKMSSFNLSRIVTLTPFCTIANKSSL
Sbjct: 2821 STSAWSSSFSLDTVGSYGCVKCPANNMEYLVGVSIKMSSFNLSRIVTLTPFCTIANKSSL 2880
Query: 2881 ELEVGEIASDGSMPTNKWNYIASSECLPFWPESLSGKLCVRVVGCEGSSKPFFYNRQDNG 2940
ELEVGEIASDGSMPTNKWNYIASSECLPFWPESLSGKLCVRVVGCEGSSKPFFYNRQDNG
Sbjct: 2881 ELEVGEIASDGSMPTNKWNYIASSECLPFWPESLSGKLCVRVVGCEGSSKPFFYNRQDNG 2940
Query: 2941 TLLSLEDLNGGILVDVNTAEHSTVITFSDYHEGSAPALIMNHTPWDILTYKQSGSPEEMV 3000
TLLSLEDLNGGILVDVNTAEHSTVITFSDYHEGSAPALIMNHTPWDILTYKQSGSPEEMV
Sbjct: 2941 TLLSLEDLNGGILVDVNTAEHSTVITFSDYHEGSAPALIMNHTPWDILTYKQSGSPEEMV 3000
Query: 3001 LLPRQARLFAWADPTGTRKLTWTYAANVGEHDLLKDGCGQFPYDANIQIHWVSFLDGRQR 3060
LLPRQARLFAWADPTGTRKLTWTYAANVGEHDLLKDGCGQFPYDANIQIHWVSFLDGRQR
Sbjct: 3001 LLPRQARLFAWADPTGTRKLTWTYAANVGEHDLLKDGCGQFPYDANIQIHWVSFLDGRQR 3060
Query: 3061 VLLFTDDVALVSKALQAEEMEQADYEITLSLHSLGLSLVNNESKQEVSYIGITSSGVVWE 3120
VLLFTDDVALVSKALQAEEMEQADYEITLSLHSLGLSLVNNESKQEVSYIGITSSGVVWE
Sbjct: 3061 VLLFTDDVALVSKALQAEEMEQADYEITLSLHSLGLSLVNNESKQEVSYIGITSSGVVWE 3120
Query: 3121 VKPKQKWKPFSQKQIILLEQSYQKHQISRDHGWIKLDNNFEVNFDKDPMEMRLPIRSPIK 3180
VKPKQKWKPFSQKQIILLEQSYQKHQISRDHGWIKLDNNFEVNFDKDPMEMRLPIRSPIK
Sbjct: 3121 VKPKQKWKPFSQKQIILLEQSYQKHQISRDHGWIKLDNNFEVNFDKDPMEMRLPIRSPIK 3180
Query: 3181 RDFLSGIQIEFKQSSHQRSLRARLYWLQVDNQLPGAMFPVVFHPVAPPKSIALDSEPKPF 3240
RDFLSGIQIEFKQSSHQRSLRARLYWLQVDNQLPGAMFPVVFHPVAPPKSIALDSEPKPF
Sbjct: 3181 RDFLSGIQIEFKQSSHQRSLRARLYWLQVDNQLPGAMFPVVFHPVAPPKSIALDSEPKPF 3240
Query: 3241 IDVSVITRFNEYSKVLQFKYFMVLIQEMALKIDQGFLGAIIALFTPTTDPEAERRRTKLI 3300
IDVSVITRFNEYSKVLQFKYFMVLIQEMALKIDQGFLGAIIALFTPTTDPEAERRRTKLI
Sbjct: 3241 IDVSVITRFNEYSKVLQFKYFMVLIQEMALKIDQGFLGAIIALFTPTTDPEAERRRTKLI 3300
Query: 3301 QQDIDALNAELMETSMTDMSILSFFEHFHISPVKLHLSLSLGSGGEESDKEKQEMFAVHS 3360
QQDIDALNAELMETSMTDMSILSFFEHFHISPVKLHLSLSLGSGGEESDKEKQEMFAVHS
Sbjct: 3301 QQDIDALNAELMETSMTDMSILSFFEHFHISPVKLHLSLSLGSGGEESDKEKQEMFAVHS 3360
Query: 3361 VNLLLKSIGATLTDVDDLIFKLAYYEIRYQFYKRDQLIWSVVRHYSEQFLKQMYVLVLGL 3420
VNLLLKSIGATLTDVDDLIFKLAYYEIRYQFYKRDQLIWSVVRHYSEQFLKQMYVLVLGL
Sbjct: 3361 VNLLLKSIGATLTDVDDLIFKLAYYEIRYQFYKRDQLIWSVVRHYSEQFLKQMYVLVLGL 3420
Query: 3421 DVLGNPFGLIRGLSEGVEALFYEPFQGAVQGPEEFAEGLVIGVRSLFGHTVGGAAGVVSR 3480
DVLGNPFGLIRGLSEGVEALFYEPFQGAVQGPEEFAEGLVIGVRSLFGHTVGGAAGVVSR
Sbjct: 3421 DVLGNPFGLIRGLSEGVEALFYEPFQGAVQGPEEFAEGLVIGVRSLFGHTVGGAAGVVSR 3480
Query: 3481 ITGSVGKGLAAITMDKEYQQKRREELSRQPRDFGDSLARGGKGFLRGVVGGVTGIITKPV 3540
ITGSVGKGLAAITMDKEYQQKRREELSRQPRDFGDSLARGGKGFLRGVVGGVTGIITKPV
Sbjct: 3481 ITGSVGKGLAAITMDKEYQQKRREELSRQPRDFGDSLARGGKGFLRGVVGGVTGIITKPV 3540
Query: 3541 EGAKKEGAAGFFKGIGKGLVGAVARPTGGIVDMASSTFQGIQRAAESTEEVSSLRPPRLI 3600
EGAKKEGAAGFFKGIGKGLVGAVARPTGGIVDMASSTFQGIQRAAESTEEVSSLRPPRLI
Sbjct: 3541 EGAKKEGAAGFFKGIGKGLVGAVARPTGGIVDMASSTFQGIQRAAESTEEVSSLRPPRLI 3600
Query: 3601 HEDGIIRPYDRQESEGSDLLENHIK 3625
HEDGIIRPYDRQESEGSDLLE ++
Sbjct: 3601 HEDGIIRPYDRQESEGSDLLEQELE 3625
>gi|66348091 vacuolar protein sorting 13C protein isoform 1B [Homo
sapiens]
Length = 3585
Score = 6995 bits (18150), Expect = 0.0
Identities = 3578/3625 (98%), Positives = 3580/3625 (98%), Gaps = 43/3625 (1%)
Query: 1 MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAG 60
MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAG
Sbjct: 1 MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAG 60
Query: 61 QIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEE 120
QIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEE
Sbjct: 61 QIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEE 120
Query: 121 ALQKAAEKGTHSGEFIYGLENFVYKDIKPGRKRKKHKKHFKKPFKGLDRSKDKPKEAKKD 180
ALQKAAEK DKPKEAKKD
Sbjct: 121 ALQKAAEK-------------------------------------------DKPKEAKKD 137
Query: 181 TFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLGELSLLTANEHWTPCILN 240
TFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLGELSLLTANEHWTPCILN
Sbjct: 138 TFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLGELSLLTANEHWTPCILN 197
Query: 241 EADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILDQLKNEILTSGNIPPNYQYIFQPIS 300
EADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILDQLKNEILTSGNIPPNYQYIFQPIS
Sbjct: 198 EADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILDQLKNEILTSGNIPPNYQYIFQPIS 257
Query: 301 ASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKPQYLSMIDLLESVDYMVRNAPYRKY 360
ASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKPQYLSMIDLLESVDYMVRNAPYRKY
Sbjct: 258 ASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKPQYLSMIDLLESVDYMVRNAPYRKY 317
Query: 361 KPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIKKHRQLLKSYKIAYKNKLTQSK 420
KPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIKKHRQLLKSYKIAYKNKLTQSK
Sbjct: 318 KPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIKKHRQLLKSYKIAYKNKLTQSK 377
Query: 421 VSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKSADTGEKRGGWFSGLWGK 480
VSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKSADTGEKRGGWFSGLWGK
Sbjct: 378 VSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKSADTGEKRGGWFSGLWGK 437
Query: 481 KESKKKDEESLIPETIDDLMTPEEKDKLFTAIGYSESTHNLTLPKQYVAHIMTLKLVSTS 540
KESKKKDEESLIPETIDDLMTPEEKDKLFTAIGYSESTHNLTLPKQYVAHIMTLKLVSTS
Sbjct: 438 KESKKKDEESLIPETIDDLMTPEEKDKLFTAIGYSESTHNLTLPKQYVAHIMTLKLVSTS 497
Query: 541 VTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVEAKLEHWYITGLRQQDIVPSLVASI 600
VTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVEAKLEHWYITGLRQQDIVPSLVASI
Sbjct: 498 VTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVEAKLEHWYITGLRQQDIVPSLVASI 557
Query: 601 GDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIYDAKTVNAVVEFFQSNKGLDLEQIT 660
GDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIYDAKTVNAVVEFFQSNKGLDLEQIT
Sbjct: 558 GDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIYDAKTVNAVVEFFQSNKGLDLEQIT 617
Query: 661 SATLMKLEEIKERTATGLTHIIETRKVLDLRINLKPSYLVVPQTGFHHEKSDLLILDFGT 720
SATLMKLEEIKERTATGLTHIIETRKVLDLRINLKPSYLVVPQTGFHHEKSDLLILDFGT
Sbjct: 618 SATLMKLEEIKERTATGLTHIIETRKVLDLRINLKPSYLVVPQTGFHHEKSDLLILDFGT 677
Query: 721 FQLNSKDQGLQKTTNSSLEEIMDKAYDKFDVEIKNVQLLFARAEETWKKCRFQHPSTMHI 780
FQLNSKDQGLQKTTNSSLEEIMDKAYDKFDVEIKNVQLLFARAEETWKKCRFQHPSTMHI
Sbjct: 678 FQLNSKDQGLQKTTNSSLEEIMDKAYDKFDVEIKNVQLLFARAEETWKKCRFQHPSTMHI 737
Query: 781 LQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVRISDQKMKDVLYLMNSIPLPQKSSA 840
LQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVRISDQKMKDVLYLMNSIPLPQKSSA
Sbjct: 738 LQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVRISDQKMKDVLYLMNSIPLPQKSSA 797
Query: 841 QSPERQVSSIPIISGGTKGLLGTSLLLDTVESESDDEYFDAEDGEPQTCKSMKGSELKKA 900
QSPERQVSSIPIISGGTKGLLGTSLLLDTVESESDDEYFDAEDGEPQTCKSMKGSELKKA
Sbjct: 798 QSPERQVSSIPIISGGTKGLLGTSLLLDTVESESDDEYFDAEDGEPQTCKSMKGSELKKA 857
Query: 901 AEVPNEELINLLLKFEIKEVILEFTKQQKEEDTILVFNVTQLGTEATMRTFDLTVVSYLK 960
AEVPNEELINLLLKFEIKEVILEFTKQQKEEDTILVFNVTQLGTEATMRTFDLTVVSYLK
Sbjct: 858 AEVPNEELINLLLKFEIKEVILEFTKQQKEEDTILVFNVTQLGTEATMRTFDLTVVSYLK 917
Query: 961 KISLDYHEIEGSKRKPLHLISSSDKPGLDLLKVEYIKADKNGPSFQTAFGKTEQTVKVAF 1020
KISLDYHEIEGSKRKPLHLISSSDKPGLDLLKVEYIKADKNGPSFQTAFGKTEQTVKVAF
Sbjct: 918 KISLDYHEIEGSKRKPLHLISSSDKPGLDLLKVEYIKADKNGPSFQTAFGKTEQTVKVAF 977
Query: 1021 SSLNLLLQTQALVASINYLTTIIPSDDQSISVAKEVQISTEKQQKNSTLPKAIVSSRDSD 1080
SSLNLLLQTQALVASINYLTTIIPSDDQSISVAKEVQISTEKQQKNSTLPKAIVSSRDSD
Sbjct: 978 SSLNLLLQTQALVASINYLTTIIPSDDQSISVAKEVQISTEKQQKNSTLPKAIVSSRDSD 1037
Query: 1081 IIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSSLSLQSRKQSLFARLENIIVTDVDPK 1140
IIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSSLSLQSRKQSLFARLENIIVTDVDPK
Sbjct: 1038 IIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSSLSLQSRKQSLFARLENIIVTDVDPK 1097
Query: 1141 TVHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMSKVDGVLSLNVGCIQIVYLHKFLMSL 1200
TVHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMSKVDGVLSLNVGCIQIVYLHKFLMSL
Sbjct: 1098 TVHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMSKVDGVLSLNVGCIQIVYLHKFLMSL 1157
Query: 1201 LNFLNNFQTAKESLSAATAQAAERAATSVKDLAQRSFRVSINIDLKAPVIVIPQSSISTN 1260
LNFLNNFQTAKESLSAATAQAAERAATSVKDLAQRSFRVSINIDLKAPVIVIPQSSISTN
Sbjct: 1158 LNFLNNFQTAKESLSAATAQAAERAATSVKDLAQRSFRVSINIDLKAPVIVIPQSSISTN 1217
Query: 1261 AVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQLTKLTLYRTVIQPGIYHPDIQLLHP 1320
AVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQLTKLTLYRTVIQPGIYHPDIQLLHP
Sbjct: 1218 AVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQLTKLTLYRTVIQPGIYHPDIQLLHP 1277
Query: 1321 INLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLNQEDLNLLFRILTENLCEGTEDLDK 1380
INLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLNQEDLNLLFRILTENLCEGTEDLDK
Sbjct: 1278 INLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLNQEDLNLLFRILTENLCEGTEDLDK 1337
Query: 1381 VKPRVQETGEIKEPLEISISQDVHDSKNTLTTGVEEIRSVDIINMLLNFEIKEVVVTLMK 1440
VKPRVQETGEIKEPLEISISQDVHDSKNTLTTGVEEIRSVDIINMLLNFEIKEVVVTLMK
Sbjct: 1338 VKPRVQETGEIKEPLEISISQDVHDSKNTLTTGVEEIRSVDIINMLLNFEIKEVVVTLMK 1397
Query: 1441 KSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFDFTDSKGEPLHIINSSNV 1500
KSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFDFTDSKGEPLHIINSSNV
Sbjct: 1398 KSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFDFTDSKGEPLHIINSSNV 1457
Query: 1501 TDEPLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLHLEALLSFMDFLSSAAPF 1560
TDEPLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLHLEALLSFMDFLSSAAPF
Sbjct: 1458 TDEPLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLHLEALLSFMDFLSSAAPF 1517
Query: 1561 SEPSSSEKESELKPLVGESRSIAVKAVSSNISQKDVFDLKITAELNAFNVFVCDQKCNIA 1620
SEPSSSEKESELKPLVGESRSIAVKAVSSNISQKDVFDLKITAELNAFNVFVCDQKCNIA
Sbjct: 1518 SEPSSSEKESELKPLVGESRSIAVKAVSSNISQKDVFDLKITAELNAFNVFVCDQKCNIA 1577
Query: 1621 DIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQSIHKKAVSILGDEVFRFQLTLYPDA 1680
DIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQSIHKKAVSILGDEVFRFQLTLYPDA
Sbjct: 1578 DIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQSIHKKAVSILGDEVFRFQLTLYPDA 1637
Query: 1681 TEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQTAKEALSTATVQAAERA 1740
TEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQTAKEALSTATVQAAERA
Sbjct: 1638 TEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQTAKEALSTATVQAAERA 1697
Query: 1741 ASSMKDLAQKSFRLLMDINLKAPVIIIPQSSVSPNAVIADLGLIRVENKFSLVPMEHYSL 1800
ASSMKDLAQKSFRLLMDINLKAPVIIIPQSSVSPNAVIADLGLIRVENKFSLVPMEHYSL
Sbjct: 1698 ASSMKDLAQKSFRLLMDINLKAPVIIIPQSSVSPNAVIADLGLIRVENKFSLVPMEHYSL 1757
Query: 1801 PPVIDKMNIELTQLKLSRTILQASLPQNDIEILKPVNMLLSIQRNLAAAWYVQIPGMEIK 1860
PPVIDKMNIELTQLKLSRTILQASLPQNDIEILKPVNMLLSIQRNLAAAWYVQIPGMEIK
Sbjct: 1758 PPVIDKMNIELTQLKLSRTILQASLPQNDIEILKPVNMLLSIQRNLAAAWYVQIPGMEIK 1817
Query: 1861 GKLKPMQVALSEDDLTVLMKILLENLGEASSQPSPTQSVQETVRVRKVDVSSVPDHLKEQ 1920
GKLKPMQVALSEDDLTVLMKILLENLGEASSQPSPTQSVQETVRVRKVDVSSVPDHLKEQ
Sbjct: 1818 GKLKPMQVALSEDDLTVLMKILLENLGEASSQPSPTQSVQETVRVRKVDVSSVPDHLKEQ 1877
Query: 1921 EDWTDSKLSMNQIVSLQFDFHFESLSIILYNNDINQESGVAFHNDSFQLGELRLHLMASS 1980
EDWTDSKLSMNQIVSLQFDFHFESLSIILYNNDINQESGVAFHNDSFQLGELRLHLMASS
Sbjct: 1878 EDWTDSKLSMNQIVSLQFDFHFESLSIILYNNDINQESGVAFHNDSFQLGELRLHLMASS 1937
Query: 1981 GKMFKDGSMNVSVKLKTCTLDDLREGIERATSRMIDRKNDQDNNSSMIDISYKQDKNGSQ 2040
GKMFKDGSMNVSVKLKTCTLDDLREGIERATSRMIDRKNDQDNNSSMIDISYKQDKNGSQ
Sbjct: 1938 GKMFKDGSMNVSVKLKTCTLDDLREGIERATSRMIDRKNDQDNNSSMIDISYKQDKNGSQ 1997
Query: 2041 IDAVLDKLYVCASVEFLMTVADFFIKAVPQSPENVAKETQILPRQTATGKVKIEKDDSVR 2100
IDAVLDKLYVCASVEFLMTVADFFIKAVPQSPENVAKETQILPRQTATGKVKIEKDDSVR
Sbjct: 1998 IDAVLDKLYVCASVEFLMTVADFFIKAVPQSPENVAKETQILPRQTATGKVKIEKDDSVR 2057
Query: 2101 PNMTLKAMITDPEVVFVASLTKADAPALTASFQCNLSLSTSKLEQMMEASVRDLKVLACP 2160
PNMTLKAMITDPEVVFVASLTKADAPALTASFQCNLSLSTSKLEQMMEASVRDLKVLACP
Sbjct: 2058 PNMTLKAMITDPEVVFVASLTKADAPALTASFQCNLSLSTSKLEQMMEASVRDLKVLACP 2117
Query: 2161 FLREKRGKNITTVLQPCSLFMEKCTWASGKQNINIMVKEFIIKISPIILNTVLTIMAALS 2220
FLREKRGKNITTVLQPCSLFMEKCTWASGKQNINIMVKEFIIKISPIILNTVLTIMAALS
Sbjct: 2118 FLREKRGKNITTVLQPCSLFMEKCTWASGKQNINIMVKEFIIKISPIILNTVLTIMAALS 2177
Query: 2221 PKTKEDGSKDTSKEMENLWGIKSINDYNTWFLGVDTATEITESFKGIEHSLIEENCGVVV 2280
PKTKEDGSKDTSKEMENLWGIKSINDYNTWFLGVDTATEITESFKGIEHSLIEENCGVVV
Sbjct: 2178 PKTKEDGSKDTSKEMENLWGIKSINDYNTWFLGVDTATEITESFKGIEHSLIEENCGVVV 2237
Query: 2281 ESIQVTLECGLGHRTVPLLLAESKFSGNIKNWTSLMAAVADVTLQVHYYNEIHAVWEPLI 2340
ESIQVTLECGLGHRTVPLLLAESKFSGNIKNWTSLMAAVADVTLQVHYYNEIHAVWEPLI
Sbjct: 2238 ESIQVTLECGLGHRTVPLLLAESKFSGNIKNWTSLMAAVADVTLQVHYYNEIHAVWEPLI 2297
Query: 2341 ERVEGKRQWNLRLDVKKNPVQDKSLLPGDDFIPEPQMAIHISSGNTMNITISKSCLNVFN 2400
ERVEGKRQWNLRLDVKKNPVQDKSLLPGDDFIPEPQMAIHISSGNTMNITISKSCLNVFN
Sbjct: 2298 ERVEGKRQWNLRLDVKKNPVQDKSLLPGDDFIPEPQMAIHISSGNTMNITISKSCLNVFN 2357
Query: 2401 NLAKGFSEGTASTFDYSLKDRAPFTVKNAVGVPIKVKPNCNLRVMGFPEKSDIFDVDAGQ 2460
NLAKGFSEGTASTFDYSLKDRAPFTVKNAVGVPIKVKPNCNLRVMGFPEKSDIFDVDAGQ
Sbjct: 2358 NLAKGFSEGTASTFDYSLKDRAPFTVKNAVGVPIKVKPNCNLRVMGFPEKSDIFDVDAGQ 2417
Query: 2461 NLELEYASMVPSSQGNLSILSRQESSFFTLTIVPHGYTEVANIPVARPGRRLYNVRNPNA 2520
NLELEYASMVPSSQGNLSILSRQESSFFTLTIVPHGYTEVANIPVARPGRRLYNVRNPNA
Sbjct: 2418 NLELEYASMVPSSQGNLSILSRQESSFFTLTIVPHGYTEVANIPVARPGRRLYNVRNPNA 2477
Query: 2521 SHSDSVLVQIDATEGNKVITLRSPLQIKNHFSIAFIIYKFVKNVKLLERIGIARPEEEFH 2580
SHSDSVLVQIDATEGNKVITLRSPLQIKNHFSIAFIIYKFVKNVKLLERIGIARPEEEFH
Sbjct: 2478 SHSDSVLVQIDATEGNKVITLRSPLQIKNHFSIAFIIYKFVKNVKLLERIGIARPEEEFH 2537
Query: 2581 VPLDSYRCQLFIQPAGILEHQYKESTTYISWKEELHRSREVRCMLQCPSVEVSFLPLIVN 2640
VPLDSYRCQLFIQPAGILEHQYKESTTYISWKEELHRSREVRCMLQCPSVEVSFLPLIVN
Sbjct: 2538 VPLDSYRCQLFIQPAGILEHQYKESTTYISWKEELHRSREVRCMLQCPSVEVSFLPLIVN 2597
Query: 2641 TVALPDELSYICTHGEDWDVAYIIHLYPSLTLRNLLPYSLRYLLEGTAETHELAEGSTAD 2700
TVALPDELSYICTHGEDWDVAYIIHLYPSLTLRNLLPYSLRYLLEGTAETHELAEGSTAD
Sbjct: 2598 TVALPDELSYICTHGEDWDVAYIIHLYPSLTLRNLLPYSLRYLLEGTAETHELAEGSTAD 2657
Query: 2701 VLHSRISGEIMELVLVKYQGKNWNGHFRIRDTLPEFFPVCFSSDSTEVTTVDLSVHVRRI 2760
VLHSRISGEIMELVLVKYQGKNWNGHFRIRDTLPEFFPVCFSSDSTEVTTVDLSVHVRRI
Sbjct: 2658 VLHSRISGEIMELVLVKYQGKNWNGHFRIRDTLPEFFPVCFSSDSTEVTTVDLSVHVRRI 2717
Query: 2761 GSRMVLSVFSPYWLINKTTRVLQYRSEDIHVKHPADFRDIILFSFKKKNIFTKNKVQLKI 2820
GSRMVLSVFSPYWLINKTTRVLQYRSEDIHVKHPADFRDIILFSFKKKNIFTKNKVQLKI
Sbjct: 2718 GSRMVLSVFSPYWLINKTTRVLQYRSEDIHVKHPADFRDIILFSFKKKNIFTKNKVQLKI 2777
Query: 2821 STSAWSSSFSLDTVGSYGCVKCPANNMEYLVGVSIKMSSFNLSRIVTLTPFCTIANKSSL 2880
STSAWSSSFSLDTVGSYGCVKCPANNMEYLVGVSIKMSSFNLSRIVTLTPFCTIANKSSL
Sbjct: 2778 STSAWSSSFSLDTVGSYGCVKCPANNMEYLVGVSIKMSSFNLSRIVTLTPFCTIANKSSL 2837
Query: 2881 ELEVGEIASDGSMPTNKWNYIASSECLPFWPESLSGKLCVRVVGCEGSSKPFFYNRQDNG 2940
ELEVGEIASDGSMPTNKWNYIASSECLPFWPESLSGKLCVRVVGCEGSSKPFFYNRQDNG
Sbjct: 2838 ELEVGEIASDGSMPTNKWNYIASSECLPFWPESLSGKLCVRVVGCEGSSKPFFYNRQDNG 2897
Query: 2941 TLLSLEDLNGGILVDVNTAEHSTVITFSDYHEGSAPALIMNHTPWDILTYKQSGSPEEMV 3000
TLLSLEDLNGGILVDVNTAEHSTVITFSDYHEGSAPALIMNHTPWDILTYKQSGSPEEMV
Sbjct: 2898 TLLSLEDLNGGILVDVNTAEHSTVITFSDYHEGSAPALIMNHTPWDILTYKQSGSPEEMV 2957
Query: 3001 LLPRQARLFAWADPTGTRKLTWTYAANVGEHDLLKDGCGQFPYDANIQIHWVSFLDGRQR 3060
LLPRQARLFAWADPTGTRKLTWTYAANVGEHDLLKDGCGQFPYDANIQIHWVSFLDGRQR
Sbjct: 2958 LLPRQARLFAWADPTGTRKLTWTYAANVGEHDLLKDGCGQFPYDANIQIHWVSFLDGRQR 3017
Query: 3061 VLLFTDDVALVSKALQAEEMEQADYEITLSLHSLGLSLVNNESKQEVSYIGITSSGVVWE 3120
VLLFTDDVALVSKALQAEEMEQADYEITLSLHSLGLSLVNNESKQEVSYIGITSSGVVWE
Sbjct: 3018 VLLFTDDVALVSKALQAEEMEQADYEITLSLHSLGLSLVNNESKQEVSYIGITSSGVVWE 3077
Query: 3121 VKPKQKWKPFSQKQIILLEQSYQKHQISRDHGWIKLDNNFEVNFDKDPMEMRLPIRSPIK 3180
VKPKQKWKPFSQKQIILLEQSYQKHQISRDHGWIKLDNNFEVNFDKDPMEMRLPIRSPIK
Sbjct: 3078 VKPKQKWKPFSQKQIILLEQSYQKHQISRDHGWIKLDNNFEVNFDKDPMEMRLPIRSPIK 3137
Query: 3181 RDFLSGIQIEFKQSSHQRSLRARLYWLQVDNQLPGAMFPVVFHPVAPPKSIALDSEPKPF 3240
RDFLSGIQIEFKQSSHQRSLRARLYWLQVDNQLPGAMFPVVFHPVAPPKSIALDSEPKPF
Sbjct: 3138 RDFLSGIQIEFKQSSHQRSLRARLYWLQVDNQLPGAMFPVVFHPVAPPKSIALDSEPKPF 3197
Query: 3241 IDVSVITRFNEYSKVLQFKYFMVLIQEMALKIDQGFLGAIIALFTPTTDPEAERRRTKLI 3300
IDVSVITRFNEYSKVLQFKYFMVLIQEMALKIDQGFLGAIIALFTPTTDPEAERRRTKLI
Sbjct: 3198 IDVSVITRFNEYSKVLQFKYFMVLIQEMALKIDQGFLGAIIALFTPTTDPEAERRRTKLI 3257
Query: 3301 QQDIDALNAELMETSMTDMSILSFFEHFHISPVKLHLSLSLGSGGEESDKEKQEMFAVHS 3360
QQDIDALNAELMETSMTDMSILSFFEHFHISPVKLHLSLSLGSGGEESDKEKQEMFAVHS
Sbjct: 3258 QQDIDALNAELMETSMTDMSILSFFEHFHISPVKLHLSLSLGSGGEESDKEKQEMFAVHS 3317
Query: 3361 VNLLLKSIGATLTDVDDLIFKLAYYEIRYQFYKRDQLIWSVVRHYSEQFLKQMYVLVLGL 3420
VNLLLKSIGATLTDVDDLIFKLAYYEIRYQFYKRDQLIWSVVRHYSEQFLKQMYVLVLGL
Sbjct: 3318 VNLLLKSIGATLTDVDDLIFKLAYYEIRYQFYKRDQLIWSVVRHYSEQFLKQMYVLVLGL 3377
Query: 3421 DVLGNPFGLIRGLSEGVEALFYEPFQGAVQGPEEFAEGLVIGVRSLFGHTVGGAAGVVSR 3480
DVLGNPFGLIRGLSEGVEALFYEPFQGAVQGPEEFAEGLVIGVRSLFGHTVGGAAGVVSR
Sbjct: 3378 DVLGNPFGLIRGLSEGVEALFYEPFQGAVQGPEEFAEGLVIGVRSLFGHTVGGAAGVVSR 3437
Query: 3481 ITGSVGKGLAAITMDKEYQQKRREELSRQPRDFGDSLARGGKGFLRGVVGGVTGIITKPV 3540
ITGSVGKGLAAITMDKEYQQKRREELSRQPRDFGDSLARGGKGFLRGVVGGVTGIITKPV
Sbjct: 3438 ITGSVGKGLAAITMDKEYQQKRREELSRQPRDFGDSLARGGKGFLRGVVGGVTGIITKPV 3497
Query: 3541 EGAKKEGAAGFFKGIGKGLVGAVARPTGGIVDMASSTFQGIQRAAESTEEVSSLRPPRLI 3600
EGAKKEGAAGFFKGIGKGLVGAVARPTGGIVDMASSTFQGIQRAAESTEEVSSLRPPRLI
Sbjct: 3498 EGAKKEGAAGFFKGIGKGLVGAVARPTGGIVDMASSTFQGIQRAAESTEEVSSLRPPRLI 3557
Query: 3601 HEDGIIRPYDRQESEGSDLLENHIK 3625
HEDGIIRPYDRQESEGSDLLE ++
Sbjct: 3558 HEDGIIRPYDRQESEGSDLLEQELE 3582
>gi|66346674 vacuolar protein sorting 13A isoform A [Homo sapiens]
Length = 3174
Score = 1700 bits (4402), Expect = 0.0
Identities = 1005/2610 (38%), Positives = 1544/2610 (59%), Gaps = 150/2610 (5%)
Query: 1188 IQIVYLHKFLMSLLNFLNNFQTAKE----SLSAATAQAAE----RAATSVKDLAQRSFRV 1239
++I+Y + + S++ F F+ KE L+AAT E + AT + + + +
Sbjct: 589 LEIIYDARTVNSIVEF---FRPPKEVHLAQLTAATLTKLEEFRSKTATGLLYIIETQKVL 645
Query: 1240 SINIDLKAPVIVIPQSSI---STNAVVVDLGLIRV----HNQFSLVSDEDYLNPPVIDR- 1291
+ I+LKA I++PQ I ++N +++DLG ++V ++ V + ++DR
Sbjct: 646 DLKINLKASYIIVPQDGIFSPTSNLLLLDLGHLKVTSKSRSELPDVKQGEANLKEIMDRA 705
Query: 1292 ---MDVQLTKLTL--------YRTVIQPGIYHPDIQLLHPINLE------FLVNRNLAAS 1334
D+QLT + L +R + + I + NLE F+ R
Sbjct: 706 YDSFDIQLTSVQLLYSRVGDNWREARKLSVSTQHILVPMHFNLELSKAMVFMDVRMPKFK 765
Query: 1335 WYHKVPVVEIK-------GHLDSMNVSLNQEDLNLL------FRILTENLCEGTEDLDKV 1381
Y K+P++ ++ G ++ + E + + F+I T ++ K+
Sbjct: 766 IYGKLPLISLRISDKKLQGIMELIESIPKPEPVTEVSAPVKSFQIQTSTSLGTSQISQKI 825
Query: 1382 KPRVQETGEIKEPLEISISQDVHDSKNT-------LTTGVEEIR---------SVDIINM 1425
P + E+ E ++ D+ + TGV+ IR SV++
Sbjct: 826 IPLL----ELPSVSEDDSEEEFFDAPCSPLEEPLQFPTGVKSIRTRKLQKQDCSVNMTTF 881
Query: 1426 LLNFEIKEVVVTLMKKSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFDFT 1485
+ FE+ +V++ + E+ VL LG E +++TYD+ A A+LK+ ++C ++
Sbjct: 882 KIRFEVPKVLIEFYHLVGDCELSVVEILVLGLGAEIEIRTYDLKANAFLKEFCLKCPEYL 941
Query: 1486 DSKGEPLHIINSSNVTDEPLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLHLE 1545
D +P++++ + + T E LL + KA+ + P+ K+ +++ Q +KV+F+SLD+ LH E
Sbjct: 942 DENKKPVYLVTTLDNTMEDLLTLEYVKAEKNVPDLKSTYNNVLQLIKVNFSSLDIHLHTE 1001
Query: 1546 ALLSFMDFLSSAAPFSEPSSSEKESELKPLVGESRSIAVKAVSSNIS-QKDVFDLKITAE 1604
ALL+ +++L + P SE EK + + E + +K ++ +S +D+ L+I AE
Sbjct: 1002 ALLNTINYLHNILPQSE----EKSAPVSTTETEDKGDVIKKLALKLSTNEDIITLQILAE 1057
Query: 1605 LNAFNVFVCDQKCNIADIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQSIHKKAVSI 1664
L+ +F+ DQKCNI++IKI G+D+ + ++P +T++ A+L++IIV++ D+ +I+KKAV I
Sbjct: 1058 LSCLQIFIQDQKCNISEIKIEGLDSEMIMRPSETEINAKLRNIIVLDSDITAIYKKAVYI 1117
Query: 1665 LGDEVFRFQLTLYPDATEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQT 1724
G EVF F++ Y DAT G AY DM+ VD +++ VGCI++V+V KF S+L F++NFQ
Sbjct: 1118 TGKEVFSFKMVSYMDATAGSAYTDMNVVDIQVNLIVGCIEVVFVTKFLYSILAFIDNFQA 1177
Query: 1725 AKEALSTATVQAAERAASSMKDLAQKSFRLLMDINLKAPVIIIPQSSVSPNAVIADLGLI 1784
AK+AL+ ATVQAA AA+ +K+LAQ+S R+ +DIN+KAPV++IPQS VS N +AD GLI
Sbjct: 1178 AKQALAEATVQAAGMAATGVKELAQRSSRMALDINIKAPVVVIPQSPVSENVFVADFGLI 1237
Query: 1785 RVENKFSLVPMEHYSLPPVIDKMNIELTQLKLSRTILQASLPQNDIEILKPVNMLLSIQR 1844
+ N F ++ S PPVID + I+L++++L R+ Q +++L P+N+ + ++R
Sbjct: 1238 TMTNTFHMITESQSSPPPVIDLITIKLSEMRLYRSRFINDAYQEVLDLLLPLNLEVVVER 1297
Query: 1845 NLAAAWYVQIPGMEIKGKLKPMQVALSEDDLTVLMKILLENLG-EASSQPSPTQSVQETV 1903
NL WY ++P + +LKPM+ LS++D+T + K L N+ E SP + +
Sbjct: 1298 NLCWEWYQEVPCFNVNAQLKPMEFILSQEDITTIFKTLHGNIWYEKDGSASPAVTKDQYS 1357
Query: 1904 RVRKVDVSSVPDHLKEQEDWTDSKLSMNQIV-----SLQFDFHFESLSIILYNNDINQES 1958
V ++ H T + + ++ +L F + L+++LY+ Q S
Sbjct: 1358 ATSGV-TTNASHHSGGATVVTAAVVEVHSRALLVKTTLNISFKTDDLTMVLYSPGPKQAS 1416
Query: 1959 GVAFHNDSFQLGELRLHLMASSGKMFKDGSMNVSVKLKTCTLDDLREGIERATSRMIDRK 2018
+ S +L E +L + S+ KM+ DGS S LK C LDD R +++AT RMI
Sbjct: 1417 FTDVRDPSLKLAEFKLENIISTLKMYTDGSTFSSFSLKNCILDDKRPHVKKATPRMIGLT 1476
Query: 2019 NDQDNNSSMIDISYKQDKNGSQIDAVLDKLYVCASVEFLMTVADFFIKAVPQSPENVAKE 2078
D M+DI Y++ ++G DAV ++Y+CASVEFL TVA+ F++A A E
Sbjct: 1477 VGFDKKD-MMDIKYRKVRDGCVTDAVFQEMYICASVEFLQTVANVFLEAYTTG---TAVE 1532
Query: 2079 TQILPRQTATGKVKIEKDDSVRPNMTLKAMITDPEVVFVASLTKADAPALTASFQCNLSL 2138
T + QT T K ++ +SV+ + +I +PE+VFVA +TK DAPAL + QC +
Sbjct: 1533 TSV---QTWTAKEEVPTQESVK--WEINVIIKNPEIVFVADMTKNDAPALVITTQCEICY 1587
Query: 2139 STSKLEQMMEASVRDLKVLACPFLREKRGKNITTVLQPCSLFMEKCTWASGKQNINIMVK 2198
+ M A+++DL+V ACPFL KR ITTVLQPC LF + + Q I++ VK
Sbjct: 1588 KGNLENSTMTAAIKDLQVRACPFLPVKRKGKITTVLQPCDLFYQTTQKGTDPQVIDMSVK 1647
Query: 2199 EFIIKISPIILNTVLTIMAALSPKTKEDGSKDTSKEMENLWGIKSINDYNTWFLGVDTAT 2258
+K+SP+I+NT++TI +AL TKE ++T+ +LW K WFL T
Sbjct: 1648 SLTLKVSPVIINTMITITSALYT-TKETIPEETASSTAHLWEKKDTKTLKMWFLEESNET 1706
Query: 2259 EITESFKGI--EHSLIEENCGVVVESIQVTLECGLGHRTVPLLLAESKFSGNIKNWTSLM 2316
E + + +I+ N ++SI + LE G+GHRTVP+LLA+S+FSG KNW+SL+
Sbjct: 1707 EKIAPTTELVPKGEMIKMN----IDSIFIVLEAGIGHRTVPMLLAKSRFSGEGKNWSSLI 1762
Query: 2317 AAVADVTLQVHYYNEIHAVWEPLIE-----RVEGKRQWNLRLDVKKNP---VQDKSLLPG 2368
+ L+VHYYNE+ VWEPL+E + E R WNL + +KK + +
Sbjct: 1763 NLHCQLELEVHYYNEMFGVWEPLLEPLEIDQTEDFRPWNLGIKMKKKAKMAIVESDPEEE 1822
Query: 2369 DDFIPEPQMAIHISSGNTMNITISKSCLNVFNNLAKGFSEG-TASTFDYSLKDRAPFTVK 2427
+ +PE + I S + +NIT+SK L + NNL K F+E T S+ D+ +KD APF +
Sbjct: 1823 NYKVPEYKTVISFHSKDQLNITLSKCGLVMLNNLVKAFTEAATGSSADF-VKDLAPFMIL 1881
Query: 2428 NAVGVPIKVKPNCNLRVMGFPEKSDIFDVDAGQNLELEYASMVPSSQGNLSILSRQESSF 2487
N++G+ I V P+ + V+ P + + G++L ++Y + N ++ S
Sbjct: 1882 NSLGLTISVSPSDSFSVLNIPMAKS-YVLKNGESLSMDYIRTKDNDHFNA--MTSLSSKL 1938
Query: 2488 FTLTIVPHGYTEVANIPVARPGRRLYNVRNPNASHSDSVLVQIDATEGNKVITLRSPLQI 2547
F + + P ++ IP+ + GRRLY VR+ + S++ QID EG+K +T+RSP+QI
Sbjct: 1939 FFILLTPVNHSTADKIPLTKVGRRLYTVRHRESGVERSIVCQIDTVEGSKKVTIRSPVQI 1998
Query: 2548 KNHFSIAFIIYKFVKNVKLLERIGIARPEEEFHVPLDSYRCQLFIQPAGILEHQYKESTT 2607
+NHFS+ +Y+ +G A PE EF++PL SYR +F++P +Q E
Sbjct: 1999 RNHFSVPLSVYEGDT------LLGTASPENEFNIPLGSYRSFIFLKPEDE-NYQMCEGID 2051
Query: 2608 YISWKEELHRSREVRCMLQCPSVEVSFLPLIVNTVALPDELSYICTHGED-WDVAYIIHL 2666
+ EE+ ++ +C S S ++N V D L+ + + ED WD+ YI+HL
Sbjct: 2052 F----EEIIKNDGALLKKKCRSKNPSKESFLINIVPEKDNLTSLSVYSEDGWDLPYIMHL 2107
Query: 2667 YPSLTLRNLLPYSLRYLLEGTAET-HELAEGSTADVLHSRISGEIMELVLVKYQGKNWNG 2725
+P + LRNLLPY + Y +EG + L+EG +A + +++ + L L+ Y +W
Sbjct: 2108 WPPILLRNLLPYKIAYYIEGIENSVFTLSEGHSAQICTAQLGKARLHLKLLDYLNHDWKS 2167
Query: 2726 HFRIRDTLPEFFPVCFSS-DSTEVTTVDLSVHVRRIGSRMVLSVFSPYWLINKTTRVLQY 2784
+ I+ + V F+ E T +D++VH+ + V++ SPYW++NKT R+LQY
Sbjct: 2168 EYHIKPNQQDISFVSFTCVTEMEKTDLDIAVHMTYNTGQTVVAFHSPYWMVNKTGRMLQY 2227
Query: 2785 RSEDIHVKHPADFRDIILFSFKKKNIFTKNKVQLKISTSAWSSSFSLDTVGSYGCVKCPA 2844
+++ IH KHP +++ +LFSF+ + F NKVQL ++ S S+ FS+DTVGS+G VKC
Sbjct: 2228 KADGIHRKHPPNYKKPVLFSFQPNHFFNNNKVQLMVTDSELSNQFSIDTVGSHGAVKCKG 2287
Query: 2845 NNMEYLVGVSIKMSSFNLSRIVTLTPFCTIANKSSLELEVGEIASDGSMPTNKWNYIASS 2904
M+Y VGV+I +SSFN++RIVT TPF I NKS + V E +D KW +
Sbjct: 2288 LKMDYQVGVTIDLSSFNITRIVTFTPFYMIKNKSKYHISVAEEGND------KWLSLDLE 2341
Query: 2905 ECLPFWPESLSGKLCVRVVGCEGSSKPFFYNRQDNGTLLSLEDLNGGILVDVNTAEHSTV 2964
+C+PFWPE S KL ++V E K ++N+Q+N LL L++ GGI+ +VN AEHSTV
Sbjct: 2342 QCIPFWPEYASSKLLIQVERSEDPPKRIYFNKQENCILLRLDNELGGIIAEVNLAEHSTV 2401
Query: 2965 ITFSDYHEGSAPALIMNHTPWDILTYKQSGSPE-EMVLLPRQARLFAWADPTGTRKLTWT 3023
ITF DYH+G+A L++NHT +++ Y QS E E L P +A + WADP G+R+L W
Sbjct: 2402 ITFLDYHDGAATFLLINHTKNELVQYNQSSLSEIEDSLPPGKAVFYTWADPVGSRRLKWR 2461
Query: 3024 YAANVGEHDLLKDGCGQFPYDANIQ-IHWVSFLDGRQRVLLFTDDVALVSKALQAEEMEQ 3082
+ GE D P D + I+ VSF +G QR++LFT+D + ++E+ E
Sbjct: 2462 CRKSHGEVTQKDDM--MMPIDLGEKTIYLVSFFEGLQRIILFTEDPRVFKVTYESEKAEL 2519
Query: 3083 ADYEITLSLHSLGLSLVNNESKQEVSYIGITSSGVVWEVKPKQK--WKPFSQKQIILLEQ 3140
A+ EI ++L +G+SLVNN +KQEV+YIGITSS VVWE KPK+K WKP S K LE+
Sbjct: 2520 AEQEIAVALQDVGISLVNNYTKQEVAYIGITSSDVVWETKPKKKARWKPMSVKHTEKLER 2579
Query: 3141 SYQKHQISR--DHGWIKLDNNFEVNFDKDPMEMRL--PIRSPIKRDFLSGIQIEFKQSSH 3196
++++ S + I+LD N V M++ P ++R++L +++E+ S+H
Sbjct: 2580 EFKEYTESSPSEDKVIQLDTNVPVRLTPTGHNMKILQPHVIALRRNYLPALKVEYNTSAH 2639
Query: 3197 QRSLRARLYWLQVDNQLPGAMFPVVFHPVAPPKSIALDSEPKPFIDVSVITRFNEYSKVL 3256
Q S R ++Y +Q+ NQ+ GA+FP VF+PV PPKS+ +DS PKPF DVS++ R +S++
Sbjct: 2640 QSSFRIQIYRIQIQNQIHGAVFPFVFYPVKPPKSVTMDSAPKPFTDVSIVMRSAGHSQIS 2699
Query: 3257 QFKYFMVLIQEMALKIDQGFLGAIIALFTPTTDPEAERRRTKLIQQDIDALNAELMETSM 3316
+ KYF VLIQEM L++D GF+ A+ L T E +L +DI+A E S+
Sbjct: 2700 RIKYFKVLIQEMDLRLDLGFIYALTDLMTEAE--VTENTEVELFHKDIEAFKEEYKTASL 2757
Query: 3317 TDMSILSFFEHFHISPVKLHLSLSLGSGGEESDKEKQE--MFAVHSVNLLLKSIGATLTD 3374
D S +S +E+FHISP+KLHLS+SL SG EE+ KQ + VHS+NLLLKSIGATLTD
Sbjct: 2758 VDQSQVSLYEYFHISPIKLHLSVSLSSGREEAKDSKQNGGLIPVHSLNLLLKSIGATLTD 2817
Query: 3375 VDDLIFKLAYYEIRYQFYKRDQLIWSVVRHYSEQFLKQMYVLVLGLDVLGNPFGLIRGLS 3434
V D++FKLA++E+ YQF+ L V+RHYS+Q +KQMYVL+LGLDVLGNPFGLIR S
Sbjct: 2818 VQDVVFKLAFFELNYQFHTTSDLQSEVIRHYSKQAIKQMYVLILGLDVLGNPFGLIREFS 2877
Query: 3435 EGVEALFYEPFQGAVQGPEEFAEGLVIGVRSLFGHTVGGAAGVVSRITGSVGKGLAAITM 3494
EGVEA FYEP+QGA+QGPEEF EG+ +G+++L G VGG AG S+ITG++ KG+AA+TM
Sbjct: 2878 EGVEAFFYEPYQGAIQGPEEFVEGMALGLKALVGGAVGGLAGAASKITGAMAKGVAAMTM 2937
Query: 3495 DKEYQQKRREELSRQPRDFGDSLARGGKGFLRGVVGGVTGIITKPVEGAKKEGAAGFFKG 3554
D++YQQKRRE +++QP F + + RGGKG + G V G+TGI+TKP++GA+K GAAGFFKG
Sbjct: 2938 DEDYQQKRREAMNKQPAGFREGITRGGKGLVSGFVSGITGIVTKPIKGAQKGGAAGFFKG 2997
Query: 3555 IGKGLVGAVARPTGGIVDMASSTFQGIQRAAESTEEVSSLRPPRLIHEDGIIRPYDRQES 3614
+GKGLVGAVARPTGGI+DMASSTFQGI+RA E T EV SLRPPR +EDG+IRPY ++
Sbjct: 2998 VGKGLVGAVARPTGGIIDMASSTFQGIKRATE-TSEVESLRPPRFFNEDGVIRPYRLRDG 3056
Query: 3615 EGSDLLENHIKKLEGETYRYHCAIPGSKKTILMVTNRRVLCIKEVEILGLMCVDWQCPFE 3674
G+ +L+ ++ Y+Y + +K +LM+T R VL + + L C +WQ F+
Sbjct: 3057 TGNQMLQ-VMENGRFAKYKYFTHVMINKTDMLMITRRGVLFVTKGTFGQLTC-EWQYSFD 3114
Query: 3675 DFVFPP-SVSENVLKISVKE--QGLFHKKD 3701
+F P V L+I KE + +FH ++
Sbjct: 3115 EFTKEPFIVHGRRLRIEAKERVKSVFHARE 3144
Score = 1131 bits (2926), Expect = 0.0
Identities = 618/1396 (44%), Positives = 889/1396 (63%), Gaps = 82/1396 (5%)
Query: 1 MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAG 60
MV ESVV D+LNRFLGDYV +L+ SQL LGIW G VAL NLQIKENALS+LDVPFKVK G
Sbjct: 1 MVFESVVVDVLNRFLGDYVVDLDTSQLSLGIWKGAVALKNLQIKENALSQLDVPFKVKVG 60
Query: 61 QIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEE 120
I L L IPWKNLY + V A LE +YLL+VP + IKYD +KEEK L + KQ+EL RIEE
Sbjct: 61 HIGNLKLIIPWKNLYTQPVEAVLEEIYLLIVPSSRIKYDPLKEEKQLMEAKQQELKRIEE 120
Query: 121 ALQKAAEKGTHSGEFIYGLENFVYKDIKPGRKRKKHKKHFKKPFKGLDRSKDKPKEAKKD 180
A QK ++ H E K+D
Sbjct: 121 AKQKVVDQEQHLPE-------------------------------------------KQD 137
Query: 181 TFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLGELSLLTANEHWTPCILN 240
TF EKL TQ+IKN+QVKI+ IHI+YEDD+T+ +PLSFG++L LS+ T +++W PC+ +
Sbjct: 138 TFAEKLVTQIIKNLQVKISSIHIRYEDDITNRDKPLSFGISLQNLSMQTTDQYWVPCLHD 197
Query: 241 EADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILDQLKNEILTSGNIPPNYQYIFQPIS 300
E +K++ KLIRLD+L AYWNV M Y + LD LKN I+ +P Y ++F+PIS
Sbjct: 198 ETEKLVRKLIRLDNLFAYWNVKSQMFYLSDYDNSLDDLKNGIVNENIVPEGYDFVFRPIS 257
Query: 301 ASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKPQYLSMIDLLESVDYMVRNAPYRKY 360
A+AKL MN ++ + PK++ IE+ NIAIE KPQY S+++LLESVD M +N PYRK+
Sbjct: 258 ANAKLVMNRRSDFDFSAPKINLEIELHNIAIEFNKPQYFSIMELLESVDMMAQNLPYRKF 317
Query: 361 KPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIKKHRQLLKSYKIAYKNKLTQSK 420
KP +PLH + R WW YAI VLEV++ MWSW +I+KHRQ +K YK YK KLT K
Sbjct: 318 KPDVPLHHHAREWWAYAIHGVLEVNVCPRLWMWSWKHIRKHRQKVKQYKELYKKKLTSKK 377
Query: 421 VSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKSADTGEKRGGWFSGLWGK 480
E+ +++LEKTLDVFNI +ARQ A+VEV ++G K+ K+ E GWFS LW
Sbjct: 378 PPGELLVSLEELEKTLDVFNITIARQTAEVEVKKAGYKIYKEGVKDPEDNKGWFSWLWSW 437
Query: 481 KESKKKDEE-SLIPETIDDLMTPEEKDKLFTAIGYSESTHNLTLPKQYVAHIMTLKLVST 539
E +++ + PET+++++TPEEK L+ AIGYSE+ + TL K + A + L S
Sbjct: 438 SEQNTNEQQPDVQPETLEEMLTPEEKALLYEAIGYSETAVDPTLLKTFEALKFFVHLKSM 497
Query: 540 SVTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVEAKLEHWYITGLRQQDIVPSLVAS 599
S+ +REN PE++ I I T + QRPGAQA+K E K++ ++ITGL P L++S
Sbjct: 498 SIVLRENHQKPELVDIVIEEFSTLIVQRPGAQAIKFETKIDSFHITGLPDNSEKPRLLSS 557
Query: 600 IGDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIYDAKTVNAVVEFFQSNKGLDLEQI 659
+ D SL +I FE NP D Q I++++P+E+IYDA+TVN++VEFF+ K + L Q+
Sbjct: 558 L-DDAMSLFQITFEINPLDETVSQRCIIEAEPLEIIYDARTVNSIVEFFRPPKEVHLAQL 616
Query: 660 TSATLMKLEEIKERTATGLTHIIETRKVLDLRINLKPSYLVVPQTGFHHEKSDLLILDFG 719
T+ATL KLEE + +TATGL +IIET+KVLDL+INLK SY++VPQ G S+LL+LD G
Sbjct: 617 TAATLTKLEEFRSKTATGLLYIIETQKVLDLKINLKASYIIVPQDGIFSPTSNLLLLDLG 676
Query: 720 TFQLNSKDQGL---QKTTNSSLEEIMDKAYDKFDVEIKNVQLLFARAEETWKKCRFQHPS 776
++ SK + K ++L+EIMD+AYD FD+++ +VQLL++R + W++ R S
Sbjct: 677 HLKVTSKSRSELPDVKQGEANLKEIMDRAYDSFDIQLTSVQLLYSRVGDNWREARKLSVS 736
Query: 777 TMHILQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVRISDQKMKDVLYLMNSIPLPQ 836
T HIL PM ++EL+KAMV D+RM +FK+ G LPL+ +RISD+K++ ++ L+ SIP P+
Sbjct: 737 TQHILVPMHFNLELSKAMVFMDVRMPKFKIYGKLPLISLRISDKKLQGIMELIESIPKPE 796
Query: 837 KSSAQSPERQVSS-IPIISGGTKGLLGTSLLLDTV----------ESESDDEYFDAEDGE 885
P +VS+ + T LGTS + + E +S++E+FDA
Sbjct: 797 ------PVTEVSAPVKSFQIQTSTSLGTSQISQKIIPLLELPSVSEDDSEEEFFDAPCSP 850
Query: 886 -------PQTCKSMKGSELKKAAEVPNEELINLLLKFEIKEVILEFTKQQKE-EDTILVF 937
P KS++ +L+K + + + ++FE+ +V++EF + E +++
Sbjct: 851 LEEPLQFPTGVKSIRTRKLQK--QDCSVNMTTFKIRFEVPKVLIEFYHLVGDCELSVVEI 908
Query: 938 NVTQLGTEATMRTFDLTVVSYLKKISLDYHEIEGSKRKPLHLISSSDKPGLDLLKVEYIK 997
V LG E +RT+DL ++LK+ L E +KP++L+++ D DLL +EY+K
Sbjct: 909 LVLGLGAEIEIRTYDLKANAFLKEFCLKCPEYLDENKKPVYLVTTLDNTMEDLLTLEYVK 968
Query: 998 ADKNGPSFQTAFGKTEQTVKVAFSSLNLLLQTQALVASINYLTTIIP-SDDQSISVAKEV 1056
A+KN P ++ + Q +KV FSSL++ L T+AL+ +INYL I+P S+++S V+
Sbjct: 969 AEKNVPDLKSTYNNVLQLIKVNFSSLDIHLHTEALLNTINYLHNILPQSEEKSAPVS--- 1025
Query: 1057 QISTEKQQKNSTLPK-AIVSSRDSDIIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSS 1115
+TE + K + K A+ S + DII ++ A+L+ + + ++K NI+EIKI+GLDS
Sbjct: 1026 --TTETEDKGDVIKKLALKLSTNEDIITLQILAELSCLQIFIQDQKCNISEIKIEGLDSE 1083
Query: 1116 LSLQSRKQSLFARLENIIVTDVDPKTVHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMS 1175
+ ++ + + A+L NIIV D D ++KKAV I G EVF F + Y DAT G YTDM+
Sbjct: 1084 MIMRPSETEINAKLRNIIVLDSDITAIYKKAVYITGKEVFSFKMVSYMDATAGSAYTDMN 1143
Query: 1176 KVDGVLSLNVGCIQIVYLHKFLMSLLNFLNNFQTAKESLSAATAQAAERAATSVKDLAQR 1235
VD ++L VGCI++V++ KFL S+L F++NFQ AK++L+ AT QAA AAT VK+LAQR
Sbjct: 1144 VVDIQVNLIVGCIEVVFVTKFLYSILAFIDNFQAAKQALAEATVQAAGMAATGVKELAQR 1203
Query: 1236 SFRVSINIDLKAPVIVIPQSSISTNAVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQ 1295
S R++++I++KAPV+VIPQS +S N V D GLI + N F ++++ PPVID + ++
Sbjct: 1204 SSRMALDINIKAPVVVIPQSPVSENVFVADFGLITMTNTFHMITESQSSPPPVIDLITIK 1263
Query: 1296 LTKLTLYRTVIQPGIYHPDIQLLHPINLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSL 1355
L+++ LYR+ Y + LL P+NLE +V RNL WY +VP + L M L
Sbjct: 1264 LSEMRLYRSRFINDAYQEVLDLLLPLNLEVVVERNLCWEWYQEVPCFNVNAQLKPMEFIL 1323
Query: 1356 NQEDLNLLFRILTENL 1371
+QED+ +F+ L N+
Sbjct: 1324 SQEDITTIFKTLHGNI 1339
Score = 54.7 bits (130), Expect = 2e-06
Identities = 82/394 (20%), Positives = 175/394 (44%), Gaps = 57/394 (14%)
Query: 1560 FSEPSSSEKESELKP------LVGESRSIAVKAVSSNISQKD-----VFD-LKITAELNA 1607
+SE +++E++ +++P L E +++ +A+ + + D F+ LK L +
Sbjct: 437 WSEQNTNEQQPDVQPETLEEMLTPEEKALLYEAIGYSETAVDPTLLKTFEALKFFVHLKS 496
Query: 1608 FNVFVCD--QKCNIADIKIHGMDASISVKPKQTDVF--ARLKDIIVMNVDLQSIHKKAVS 1663
++ + + QK + DI I I +P + ++ + + S + +S
Sbjct: 497 MSIVLRENHQKPELVDIVIEEFSTLIVQRPGAQAIKFETKIDSFHITGLPDNSEKPRLLS 556
Query: 1664 ILGDEVFRFQLTLYPDATEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQ 1723
L D + FQ+T + + V + + ++I+Y + S++ F F+
Sbjct: 557 SLDDAMSLFQITFEINPLD-------ETVSQRCIIEAEPLEIIYDARTVNSIVEF---FR 606
Query: 1724 TAKEA----LSTATVQAAE----RAASSMKDLAQKSFRLLMDINLKAPVIIIPQSSV--- 1772
KE L+ AT+ E + A+ + + + L + INLKA II+PQ +
Sbjct: 607 PPKEVHLAQLTAATLTKLEEFRSKTATGLLYIIETQKVLDLKINLKASYIIVPQDGIFSP 666
Query: 1773 SPNAVIADLGLIRVENK----FSLVPMEHYSLPPVIDK----MNIELTQLKLSRTIL--- 1821
+ N ++ DLG ++V +K V +L ++D+ +I+LT ++L + +
Sbjct: 667 TSNLLLLDLGHLKVTSKSRSELPDVKQGEANLKEIMDRAYDSFDIQLTSVQLLYSRVGDN 726
Query: 1822 ---QASLPQNDIEILKPVNMLLSIQRNLAAAWYVQIPGMEIKGKLKPMQVALSEDDLTVL 1878
L + IL P++ L + + + V++P +I GKL + + +S+ L +
Sbjct: 727 WREARKLSVSTQHILVPMHFNLELSKAM-VFMDVRMPKFKIYGKLPLISLRISDKKLQGI 785
Query: 1879 MKILLENLGEASSQPSPTQSVQETVRVRKVDVSS 1912
M+++ E+ +P P V V+ ++ S+
Sbjct: 786 MELI-----ESIPKPEPVTEVSAPVKSFQIQTST 814
>gi|15619008 vacuolar protein sorting 13A isoform B [Homo sapiens]
Length = 3095
Score = 1679 bits (4347), Expect = 0.0
Identities = 982/2527 (38%), Positives = 1504/2527 (59%), Gaps = 145/2527 (5%)
Query: 1188 IQIVYLHKFLMSLLNFLNNFQTAKE----SLSAATAQAAE----RAATSVKDLAQRSFRV 1239
++I+Y + + S++ F F+ KE L+AAT E + AT + + + +
Sbjct: 589 LEIIYDARTVNSIVEF---FRPPKEVHLAQLTAATLTKLEEFRSKTATGLLYIIETQKVL 645
Query: 1240 SINIDLKAPVIVIPQSSI---STNAVVVDLGLIRV----HNQFSLVSDEDYLNPPVIDR- 1291
+ I+LKA I++PQ I ++N +++DLG ++V ++ V + ++DR
Sbjct: 646 DLKINLKASYIIVPQDGIFSPTSNLLLLDLGHLKVTSKSRSELPDVKQGEANLKEIMDRA 705
Query: 1292 ---MDVQLTKLTL--------YRTVIQPGIYHPDIQLLHPINLE------FLVNRNLAAS 1334
D+QLT + L +R + + I + NLE F+ R
Sbjct: 706 YDSFDIQLTSVQLLYSRVGDNWREARKLSVSTQHILVPMHFNLELSKAMVFMDVRMPKFK 765
Query: 1335 WYHKVPVVEIK-------GHLDSMNVSLNQEDLNLL------FRILTENLCEGTEDLDKV 1381
Y K+P++ ++ G ++ + E + + F+I T ++ K+
Sbjct: 766 IYGKLPLISLRISDKKLQGIMELIESIPKPEPVTEVSAPVKSFQIQTSTSLGTSQISQKI 825
Query: 1382 KPRVQETGEIKEPLEISISQDVHDSKNT-------LTTGVEEIR---------SVDIINM 1425
P + E+ E ++ D+ + TGV+ IR SV++
Sbjct: 826 IPLL----ELPSVSEDDSEEEFFDAPCSPLEEPLQFPTGVKSIRTRKLQKQDCSVNMTTF 881
Query: 1426 LLNFEIKEVVVTLMKKSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFDFT 1485
+ FE+ +V++ + E+ VL LG E +++TYD+ A A+LK+ ++C ++
Sbjct: 882 KIRFEVPKVLIEFYHLVGDCELSVVEILVLGLGAEIEIRTYDLKANAFLKEFCLKCPEYL 941
Query: 1486 DSKGEPLHIINSSNVTDEPLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLHLE 1545
D +P++++ + + T E LL + KA+ + P+ K+ +++ Q +KV+F+SLD+ LH E
Sbjct: 942 DENKKPVYLVTTLDNTMEDLLTLEYVKAEKNVPDLKSTYNNVLQLIKVNFSSLDIHLHTE 1001
Query: 1546 ALLSFMDFLSSAAPFSEPSSSEKESELKPLVGESRSIAVKAVSSNIS-QKDVFDLKITAE 1604
ALL+ +++L + P SE EK + + E + +K ++ +S +D+ L+I AE
Sbjct: 1002 ALLNTINYLHNILPQSE----EKSAPVSTTETEDKGDVIKKLALKLSTNEDIITLQILAE 1057
Query: 1605 LNAFNVFVCDQKCNIADIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQSIHKKAVSI 1664
L+ +F+ DQKCNI++IKI G+D+ + ++P +T++ A+L++IIV++ D+ +I+KKAV I
Sbjct: 1058 LSCLQIFIQDQKCNISEIKIEGLDSEMIMRPSETEINAKLRNIIVLDSDITAIYKKAVYI 1117
Query: 1665 LGDEVFRFQLTLYPDATEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQT 1724
G EVF F++ Y DAT G AY DM+ VD +++ VGCI++V+V KF S+L F++NFQ
Sbjct: 1118 TGKEVFSFKMVSYMDATAGSAYTDMNVVDIQVNLIVGCIEVVFVTKFLYSILAFIDNFQA 1177
Query: 1725 AKEALSTATVQAAERAASSMKDLAQKSFRLLMDINLKAPVIIIPQSSVSPNAVIADLGLI 1784
AK+AL+ ATVQAA AA+ +K+LAQ+S R+ +DIN+KAPV++IPQS VS N +AD GLI
Sbjct: 1178 AKQALAEATVQAAGMAATGVKELAQRSSRMALDINIKAPVVVIPQSPVSENVFVADFGLI 1237
Query: 1785 RVENKFSLVPMEHYSLPPVIDKMNIELTQLKLSRTILQASLPQNDIEILKPVNMLLSIQR 1844
+ N F ++ S PPVID + I+L++++L R+ Q +++L P+N+ + ++R
Sbjct: 1238 TMTNTFHMITESQSSPPPVIDLITIKLSEMRLYRSRFINDAYQEVLDLLLPLNLEVVVER 1297
Query: 1845 NLAAAWYVQIPGMEIKGKLKPMQVALSEDDLTVLMKILLENLG-EASSQPSPTQSVQETV 1903
NL WY ++P + +LKPM+ LS++D+T + K L N+ E SP + +
Sbjct: 1298 NLCWEWYQEVPCFNVNAQLKPMEFILSQEDITTIFKTLHGNIWYEKDGSASPAVTKDQYS 1357
Query: 1904 RVRKVDVSSVPDHLKEQEDWTDSKLSMNQIV-----SLQFDFHFESLSIILYNNDINQES 1958
V ++ H T + + ++ +L F + L+++LY+ Q S
Sbjct: 1358 ATSGV-TTNASHHSGGATVVTAAVVEVHSRALLVKTTLNISFKTDDLTMVLYSPGPKQAS 1416
Query: 1959 GVAFHNDSFQLGELRLHLMASSGKMFKDGSMNVSVKLKTCTLDDLREGIERATSRMIDRK 2018
+ S +L E +L + S+ KM+ DGS S LK C LDD R +++AT RMI
Sbjct: 1417 FTDVRDPSLKLAEFKLENIISTLKMYTDGSTFSSFSLKNCILDDKRPHVKKATPRMIGLT 1476
Query: 2019 NDQDNNSSMIDISYKQDKNGSQIDAVLDKLYVCASVEFLMTVADFFIKAVPQSPENVAKE 2078
D M+DI Y++ ++G DAV ++Y+CASVEFL TVA+ F++A A E
Sbjct: 1477 VGFDKKD-MMDIKYRKVRDGCVTDAVFQEMYICASVEFLQTVANVFLEAYTTG---TAVE 1532
Query: 2079 TQILPRQTATGKVKIEKDDSVRPNMTLKAMITDPEVVFVASLTKADAPALTASFQCNLSL 2138
T + QT T K ++ +SV+ + +I +PE+VFVA +TK DAPAL + QC +
Sbjct: 1533 TSV---QTWTAKEEVPTQESVK--WEINVIIKNPEIVFVADMTKNDAPALVITTQCEICY 1587
Query: 2139 STSKLEQMMEASVRDLKVLACPFLREKRGKNITTVLQPCSLFMEKCTWASGKQNINIMVK 2198
+ M A+++DL+V ACPFL KR ITTVLQPC LF + + Q I++ VK
Sbjct: 1588 KGNLENSTMTAAIKDLQVRACPFLPVKRKGKITTVLQPCDLFYQTTQKGTDPQVIDMSVK 1647
Query: 2199 EFIIKISPIILNTVLTIMAALSPKTKEDGSKDTSKEMENLWGIKSINDYNTWFLGVDTAT 2258
+K+SP+I+NT++TI +AL TKE ++T+ +LW K WFL T
Sbjct: 1648 SLTLKVSPVIINTMITITSALYT-TKETIPEETASSTAHLWEKKDTKTLKMWFLEESNET 1706
Query: 2259 EITESFKGI--EHSLIEENCGVVVESIQVTLECGLGHRTVPLLLAESKFSGNIKNWTSLM 2316
E + + +I+ N ++SI + LE G+GHRTVP+LLA+S+FSG KNW+SL+
Sbjct: 1707 EKIAPTTELVPKGEMIKMN----IDSIFIVLEAGIGHRTVPMLLAKSRFSGEGKNWSSLI 1762
Query: 2317 AAVADVTLQVHYYNEIHAVWEPLIE-----RVEGKRQWNLRLDVKKNP---VQDKSLLPG 2368
+ L+VHYYNE+ VWEPL+E + E R WNL + +KK + +
Sbjct: 1763 NLHCQLELEVHYYNEMFGVWEPLLEPLEIDQTEDFRPWNLGIKMKKKAKMAIVESDPEEE 1822
Query: 2369 DDFIPEPQMAIHISSGNTMNITISKSCLNVFNNLAKGFSEG-TASTFDYSLKDRAPFTVK 2427
+ +PE + I S + +NIT+SK L + NNL K F+E T S+ D+ +KD APF +
Sbjct: 1823 NYKVPEYKTVISFHSKDQLNITLSKCGLVMLNNLVKAFTEAATGSSADF-VKDLAPFMIL 1881
Query: 2428 NAVGVPIKVKPNCNLRVMGFPEKSDIFDVDAGQNLELEYASMVPSSQGNLSILSRQESSF 2487
N++G+ I V P+ + V+ P + + G++L ++Y + N ++ S
Sbjct: 1882 NSLGLTISVSPSDSFSVLNIPMAKS-YVLKNGESLSMDYIRTKDNDHFNA--MTSLSSKL 1938
Query: 2488 FTLTIVPHGYTEVANIPVARPGRRLYNVRNPNASHSDSVLVQIDATEGNKVITLRSPLQI 2547
F + + P ++ IP+ + GRRLY VR+ + S++ QID EG+K +T+RSP+QI
Sbjct: 1939 FFILLTPVNHSTADKIPLTKVGRRLYTVRHRESGVERSIVCQIDTVEGSKKVTIRSPVQI 1998
Query: 2548 KNHFSIAFIIYKFVKNVKLLERIGIARPEEEFHVPLDSYRCQLFIQPAGILEHQYKESTT 2607
+NHFS+ +Y+ +G A PE EF++PL SYR +F++P +Q E
Sbjct: 1999 RNHFSVPLSVYEGDT------LLGTASPENEFNIPLGSYRSFIFLKPEDE-NYQMCEGID 2051
Query: 2608 YISWKEELHRSREVRCMLQCPSVEVSFLPLIVNTVALPDELSYICTHGED-WDVAYIIHL 2666
+ EE+ ++ +C S S ++N V D L+ + + ED WD+ YI+HL
Sbjct: 2052 F----EEIIKNDGALLKKKCRSKNPSKESFLINIVPEKDNLTSLSVYSEDGWDLPYIMHL 2107
Query: 2667 YPSLTLRNLLPYSLRYLLEGTAET-HELAEGSTADVLHSRISGEIMELVLVKYQGKNWNG 2725
+P + LRNLLPY + Y +EG + L+EG +A + +++ + L L+ Y +W
Sbjct: 2108 WPPILLRNLLPYKIAYYIEGIENSVFTLSEGHSAQICTAQLGKARLHLKLLDYLNHDWKS 2167
Query: 2726 HFRIRDTLPEFFPVCFSS-DSTEVTTVDLSVHVRRIGSRMVLSVFSPYWLINKTTRVLQY 2784
+ I+ + V F+ E T +D++VH+ + V++ SPYW++NKT R+LQY
Sbjct: 2168 EYHIKPNQQDISFVSFTCVTEMEKTDLDIAVHMTYNTGQTVVAFHSPYWMVNKTGRMLQY 2227
Query: 2785 RSEDIHVKHPADFRDIILFSFKKKNIFTKNKVQLKISTSAWSSSFSLDTVGSYGCVKCPA 2844
+++ IH KHP +++ +LFSF+ + F NKVQL ++ S S+ FS+DTVGS+G VKC
Sbjct: 2228 KADGIHRKHPPNYKKPVLFSFQPNHFFNNNKVQLMVTDSELSNQFSIDTVGSHGAVKCKG 2287
Query: 2845 NNMEYLVGVSIKMSSFNLSRIVTLTPFCTIANKSSLELEVGEIASDGSMPTNKWNYIASS 2904
M+Y VGV+I +SSFN++RIVT TPF I NKS + V E +D KW +
Sbjct: 2288 LKMDYQVGVTIDLSSFNITRIVTFTPFYMIKNKSKYHISVAEEGND------KWLSLDLE 2341
Query: 2905 ECLPFWPESLSGKLCVRVVGCEGSSKPFFYNRQDNGTLLSLEDLNGGILVDVNTAEHSTV 2964
+C+PFWPE S KL ++V E K ++N+Q+N LL L++ GGI+ +VN AEHSTV
Sbjct: 2342 QCIPFWPEYASSKLLIQVERSEDPPKRIYFNKQENCILLRLDNELGGIIAEVNLAEHSTV 2401
Query: 2965 ITFSDYHEGSAPALIMNHTPWDILTYKQSGSPE-EMVLLPRQARLFAWADPTGTRKLTWT 3023
ITF DYH+G+A L++NHT +++ Y QS E E L P +A + WADP G+R+L W
Sbjct: 2402 ITFLDYHDGAATFLLINHTKNELVQYNQSSLSEIEDSLPPGKAVFYTWADPVGSRRLKWR 2461
Query: 3024 YAANVGEHDLLKDGCGQFPYDANIQ-IHWVSFLDGRQRVLLFTDDVALVSKALQAEEMEQ 3082
+ GE D P D + I+ VSF +G QR++LFT+D + ++E+ E
Sbjct: 2462 CRKSHGEVTQKDDM--MMPIDLGEKTIYLVSFFEGLQRIILFTEDPRVFKVTYESEKAEL 2519
Query: 3083 ADYEITLSLHSLGLSLVNNESKQEVSYIGITSSGVVWEVKPKQK--WKPFSQKQIILLEQ 3140
A+ EI ++L +G+SLVNN +KQEV+YIGITSS VVWE KPK+K WKP S K LE+
Sbjct: 2520 AEQEIAVALQDVGISLVNNYTKQEVAYIGITSSDVVWETKPKKKARWKPMSVKHTEKLER 2579
Query: 3141 SYQKHQISR--DHGWIKLDNNFEVNFDKDPMEMRL--PIRSPIKRDFLSGIQIEFKQSSH 3196
++++ S + I+LD N V M++ P ++R++L +++E+ S+H
Sbjct: 2580 EFKEYTESSPSEDKVIQLDTNVPVRLTPTGHNMKILQPHVIALRRNYLPALKVEYNTSAH 2639
Query: 3197 QRSLRARLYWLQVDNQLPGAMFPVVFHPVAPPKSIALDSEPKPFIDVSVITRFNEYSKVL 3256
Q S R ++Y +Q+ NQ+ GA+FP VF+PV PPKS+ +DS PKPF DVS++ R +S++
Sbjct: 2640 QSSFRIQIYRIQIQNQIHGAVFPFVFYPVKPPKSVTMDSAPKPFTDVSIVMRSAGHSQIS 2699
Query: 3257 QFKYFMVLIQEMALKIDQGFLGAIIALFTPTTDPEAERRRTKLIQQDIDALNAELMETSM 3316
+ KYF VLIQEM L++D GF+ A+ L T E +L +DI+A E S+
Sbjct: 2700 RIKYFKVLIQEMDLRLDLGFIYALTDLMTEAE--VTENTEVELFHKDIEAFKEEYKTASL 2757
Query: 3317 TDMSILSFFEHFHISPVKLHLSLSLGSGGEESDKEKQE--MFAVHSVNLLLKSIGATLTD 3374
D S +S +E+FHISP+KLHLS+SL SG EE+ KQ + VHS+NLLLKSIGATLTD
Sbjct: 2758 VDQSQVSLYEYFHISPIKLHLSVSLSSGREEAKDSKQNGGLIPVHSLNLLLKSIGATLTD 2817
Query: 3375 VDDLIFKLAYYEIRYQFYKRDQLIWSVVRHYSEQFLKQMYVLVLGLDVLGNPFGLIRGLS 3434
V D++FKLA++E+ YQF+ L V+RHYS+Q +KQMYVL+LGLDVLGNPFGLIR S
Sbjct: 2818 VQDVVFKLAFFELNYQFHTTSDLQSEVIRHYSKQAIKQMYVLILGLDVLGNPFGLIREFS 2877
Query: 3435 EGVEALFYEPFQGAVQGPEEFAEGLVIGVRSLFGHTVGGAAGVVSRITGSVGKGLAAITM 3494
EGVEA FYEP+QGA+QGPEEF EG+ +G+++L G VGG AG S+ITG++ KG+AA+TM
Sbjct: 2878 EGVEAFFYEPYQGAIQGPEEFVEGMALGLKALVGGAVGGLAGAASKITGAMAKGVAAMTM 2937
Query: 3495 DKEYQQKRREELSRQPRDFGDSLARGGKGFLRGVVGGVTGIITKPVEGAKKEGAAGFFKG 3554
D++YQQKRRE +++QP F + + RGGKG + G V G+TGI+TKP++GA+K GAAGFFKG
Sbjct: 2938 DEDYQQKRREAMNKQPAGFREGITRGGKGLVSGFVSGITGIVTKPIKGAQKGGAAGFFKG 2997
Query: 3555 IGKGLVGAVARPTGGIVDMASSTFQGIQRAAESTEEVSSLRPPRLIHEDGIIRPYDRQES 3614
+GKGLVGAVARPTGGI+DMASSTFQGI+RA E T EV SLRPPR +EDG+IRPY ++
Sbjct: 2998 VGKGLVGAVARPTGGIIDMASSTFQGIKRATE-TSEVESLRPPRFFNEDGVIRPYRLRDG 3056
Query: 3615 EGSDLLE 3621
G+ +L+
Sbjct: 3057 TGNQMLQ 3063
Score = 1131 bits (2926), Expect = 0.0
Identities = 618/1396 (44%), Positives = 889/1396 (63%), Gaps = 82/1396 (5%)
Query: 1 MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAG 60
MV ESVV D+LNRFLGDYV +L+ SQL LGIW G VAL NLQIKENALS+LDVPFKVK G
Sbjct: 1 MVFESVVVDVLNRFLGDYVVDLDTSQLSLGIWKGAVALKNLQIKENALSQLDVPFKVKVG 60
Query: 61 QIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEE 120
I L L IPWKNLY + V A LE +YLL+VP + IKYD +KEEK L + KQ+EL RIEE
Sbjct: 61 HIGNLKLIIPWKNLYTQPVEAVLEEIYLLIVPSSRIKYDPLKEEKQLMEAKQQELKRIEE 120
Query: 121 ALQKAAEKGTHSGEFIYGLENFVYKDIKPGRKRKKHKKHFKKPFKGLDRSKDKPKEAKKD 180
A QK ++ H E K+D
Sbjct: 121 AKQKVVDQEQHLPE-------------------------------------------KQD 137
Query: 181 TFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLGELSLLTANEHWTPCILN 240
TF EKL TQ+IKN+QVKI+ IHI+YEDD+T+ +PLSFG++L LS+ T +++W PC+ +
Sbjct: 138 TFAEKLVTQIIKNLQVKISSIHIRYEDDITNRDKPLSFGISLQNLSMQTTDQYWVPCLHD 197
Query: 241 EADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILDQLKNEILTSGNIPPNYQYIFQPIS 300
E +K++ KLIRLD+L AYWNV M Y + LD LKN I+ +P Y ++F+PIS
Sbjct: 198 ETEKLVRKLIRLDNLFAYWNVKSQMFYLSDYDNSLDDLKNGIVNENIVPEGYDFVFRPIS 257
Query: 301 ASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKPQYLSMIDLLESVDYMVRNAPYRKY 360
A+AKL MN ++ + PK++ IE+ NIAIE KPQY S+++LLESVD M +N PYRK+
Sbjct: 258 ANAKLVMNRRSDFDFSAPKINLEIELHNIAIEFNKPQYFSIMELLESVDMMAQNLPYRKF 317
Query: 361 KPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIKKHRQLLKSYKIAYKNKLTQSK 420
KP +PLH + R WW YAI VLEV++ MWSW +I+KHRQ +K YK YK KLT K
Sbjct: 318 KPDVPLHHHAREWWAYAIHGVLEVNVCPRLWMWSWKHIRKHRQKVKQYKELYKKKLTSKK 377
Query: 421 VSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKSADTGEKRGGWFSGLWGK 480
E+ +++LEKTLDVFNI +ARQ A+VEV ++G K+ K+ E GWFS LW
Sbjct: 378 PPGELLVSLEELEKTLDVFNITIARQTAEVEVKKAGYKIYKEGVKDPEDNKGWFSWLWSW 437
Query: 481 KESKKKDEE-SLIPETIDDLMTPEEKDKLFTAIGYSESTHNLTLPKQYVAHIMTLKLVST 539
E +++ + PET+++++TPEEK L+ AIGYSE+ + TL K + A + L S
Sbjct: 438 SEQNTNEQQPDVQPETLEEMLTPEEKALLYEAIGYSETAVDPTLLKTFEALKFFVHLKSM 497
Query: 540 SVTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVEAKLEHWYITGLRQQDIVPSLVAS 599
S+ +REN PE++ I I T + QRPGAQA+K E K++ ++ITGL P L++S
Sbjct: 498 SIVLRENHQKPELVDIVIEEFSTLIVQRPGAQAIKFETKIDSFHITGLPDNSEKPRLLSS 557
Query: 600 IGDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIYDAKTVNAVVEFFQSNKGLDLEQI 659
+ D SL +I FE NP D Q I++++P+E+IYDA+TVN++VEFF+ K + L Q+
Sbjct: 558 L-DDAMSLFQITFEINPLDETVSQRCIIEAEPLEIIYDARTVNSIVEFFRPPKEVHLAQL 616
Query: 660 TSATLMKLEEIKERTATGLTHIIETRKVLDLRINLKPSYLVVPQTGFHHEKSDLLILDFG 719
T+ATL KLEE + +TATGL +IIET+KVLDL+INLK SY++VPQ G S+LL+LD G
Sbjct: 617 TAATLTKLEEFRSKTATGLLYIIETQKVLDLKINLKASYIIVPQDGIFSPTSNLLLLDLG 676
Query: 720 TFQLNSKDQGL---QKTTNSSLEEIMDKAYDKFDVEIKNVQLLFARAEETWKKCRFQHPS 776
++ SK + K ++L+EIMD+AYD FD+++ +VQLL++R + W++ R S
Sbjct: 677 HLKVTSKSRSELPDVKQGEANLKEIMDRAYDSFDIQLTSVQLLYSRVGDNWREARKLSVS 736
Query: 777 TMHILQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVRISDQKMKDVLYLMNSIPLPQ 836
T HIL PM ++EL+KAMV D+RM +FK+ G LPL+ +RISD+K++ ++ L+ SIP P+
Sbjct: 737 TQHILVPMHFNLELSKAMVFMDVRMPKFKIYGKLPLISLRISDKKLQGIMELIESIPKPE 796
Query: 837 KSSAQSPERQVSS-IPIISGGTKGLLGTSLLLDTV----------ESESDDEYFDAEDGE 885
P +VS+ + T LGTS + + E +S++E+FDA
Sbjct: 797 ------PVTEVSAPVKSFQIQTSTSLGTSQISQKIIPLLELPSVSEDDSEEEFFDAPCSP 850
Query: 886 -------PQTCKSMKGSELKKAAEVPNEELINLLLKFEIKEVILEFTKQQKE-EDTILVF 937
P KS++ +L+K + + + ++FE+ +V++EF + E +++
Sbjct: 851 LEEPLQFPTGVKSIRTRKLQK--QDCSVNMTTFKIRFEVPKVLIEFYHLVGDCELSVVEI 908
Query: 938 NVTQLGTEATMRTFDLTVVSYLKKISLDYHEIEGSKRKPLHLISSSDKPGLDLLKVEYIK 997
V LG E +RT+DL ++LK+ L E +KP++L+++ D DLL +EY+K
Sbjct: 909 LVLGLGAEIEIRTYDLKANAFLKEFCLKCPEYLDENKKPVYLVTTLDNTMEDLLTLEYVK 968
Query: 998 ADKNGPSFQTAFGKTEQTVKVAFSSLNLLLQTQALVASINYLTTIIP-SDDQSISVAKEV 1056
A+KN P ++ + Q +KV FSSL++ L T+AL+ +INYL I+P S+++S V+
Sbjct: 969 AEKNVPDLKSTYNNVLQLIKVNFSSLDIHLHTEALLNTINYLHNILPQSEEKSAPVS--- 1025
Query: 1057 QISTEKQQKNSTLPK-AIVSSRDSDIIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSS 1115
+TE + K + K A+ S + DII ++ A+L+ + + ++K NI+EIKI+GLDS
Sbjct: 1026 --TTETEDKGDVIKKLALKLSTNEDIITLQILAELSCLQIFIQDQKCNISEIKIEGLDSE 1083
Query: 1116 LSLQSRKQSLFARLENIIVTDVDPKTVHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMS 1175
+ ++ + + A+L NIIV D D ++KKAV I G EVF F + Y DAT G YTDM+
Sbjct: 1084 MIMRPSETEINAKLRNIIVLDSDITAIYKKAVYITGKEVFSFKMVSYMDATAGSAYTDMN 1143
Query: 1176 KVDGVLSLNVGCIQIVYLHKFLMSLLNFLNNFQTAKESLSAATAQAAERAATSVKDLAQR 1235
VD ++L VGCI++V++ KFL S+L F++NFQ AK++L+ AT QAA AAT VK+LAQR
Sbjct: 1144 VVDIQVNLIVGCIEVVFVTKFLYSILAFIDNFQAAKQALAEATVQAAGMAATGVKELAQR 1203
Query: 1236 SFRVSINIDLKAPVIVIPQSSISTNAVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQ 1295
S R++++I++KAPV+VIPQS +S N V D GLI + N F ++++ PPVID + ++
Sbjct: 1204 SSRMALDINIKAPVVVIPQSPVSENVFVADFGLITMTNTFHMITESQSSPPPVIDLITIK 1263
Query: 1296 LTKLTLYRTVIQPGIYHPDIQLLHPINLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSL 1355
L+++ LYR+ Y + LL P+NLE +V RNL WY +VP + L M L
Sbjct: 1264 LSEMRLYRSRFINDAYQEVLDLLLPLNLEVVVERNLCWEWYQEVPCFNVNAQLKPMEFIL 1323
Query: 1356 NQEDLNLLFRILTENL 1371
+QED+ +F+ L N+
Sbjct: 1324 SQEDITTIFKTLHGNI 1339
Score = 54.7 bits (130), Expect = 2e-06
Identities = 82/394 (20%), Positives = 175/394 (44%), Gaps = 57/394 (14%)
Query: 1560 FSEPSSSEKESELKP------LVGESRSIAVKAVSSNISQKD-----VFD-LKITAELNA 1607
+SE +++E++ +++P L E +++ +A+ + + D F+ LK L +
Sbjct: 437 WSEQNTNEQQPDVQPETLEEMLTPEEKALLYEAIGYSETAVDPTLLKTFEALKFFVHLKS 496
Query: 1608 FNVFVCD--QKCNIADIKIHGMDASISVKPKQTDVF--ARLKDIIVMNVDLQSIHKKAVS 1663
++ + + QK + DI I I +P + ++ + + S + +S
Sbjct: 497 MSIVLRENHQKPELVDIVIEEFSTLIVQRPGAQAIKFETKIDSFHITGLPDNSEKPRLLS 556
Query: 1664 ILGDEVFRFQLTLYPDATEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQ 1723
L D + FQ+T + + V + + ++I+Y + S++ F F+
Sbjct: 557 SLDDAMSLFQITFEINPLD-------ETVSQRCIIEAEPLEIIYDARTVNSIVEF---FR 606
Query: 1724 TAKEA----LSTATVQAAE----RAASSMKDLAQKSFRLLMDINLKAPVIIIPQSSV--- 1772
KE L+ AT+ E + A+ + + + L + INLKA II+PQ +
Sbjct: 607 PPKEVHLAQLTAATLTKLEEFRSKTATGLLYIIETQKVLDLKINLKASYIIVPQDGIFSP 666
Query: 1773 SPNAVIADLGLIRVENK----FSLVPMEHYSLPPVIDK----MNIELTQLKLSRTIL--- 1821
+ N ++ DLG ++V +K V +L ++D+ +I+LT ++L + +
Sbjct: 667 TSNLLLLDLGHLKVTSKSRSELPDVKQGEANLKEIMDRAYDSFDIQLTSVQLLYSRVGDN 726
Query: 1822 ---QASLPQNDIEILKPVNMLLSIQRNLAAAWYVQIPGMEIKGKLKPMQVALSEDDLTVL 1878
L + IL P++ L + + + V++P +I GKL + + +S+ L +
Sbjct: 727 WREARKLSVSTQHILVPMHFNLELSKAM-VFMDVRMPKFKIYGKLPLISLRISDKKLQGI 785
Query: 1879 MKILLENLGEASSQPSPTQSVQETVRVRKVDVSS 1912
M+++ E+ +P P V V+ ++ S+
Sbjct: 786 MELI-----ESIPKPEPVTEVSAPVKSFQIQTST 814
>gi|66346676 vacuolar protein sorting 13A isoform D [Homo sapiens]
Length = 3069
Score = 1679 bits (4347), Expect = 0.0
Identities = 982/2527 (38%), Positives = 1504/2527 (59%), Gaps = 145/2527 (5%)
Query: 1188 IQIVYLHKFLMSLLNFLNNFQTAKE----SLSAATAQAAE----RAATSVKDLAQRSFRV 1239
++I+Y + + S++ F F+ KE L+AAT E + AT + + + +
Sbjct: 589 LEIIYDARTVNSIVEF---FRPPKEVHLAQLTAATLTKLEEFRSKTATGLLYIIETQKVL 645
Query: 1240 SINIDLKAPVIVIPQSSI---STNAVVVDLGLIRV----HNQFSLVSDEDYLNPPVIDR- 1291
+ I+LKA I++PQ I ++N +++DLG ++V ++ V + ++DR
Sbjct: 646 DLKINLKASYIIVPQDGIFSPTSNLLLLDLGHLKVTSKSRSELPDVKQGEANLKEIMDRA 705
Query: 1292 ---MDVQLTKLTL--------YRTVIQPGIYHPDIQLLHPINLE------FLVNRNLAAS 1334
D+QLT + L +R + + I + NLE F+ R
Sbjct: 706 YDSFDIQLTSVQLLYSRVGDNWREARKLSVSTQHILVPMHFNLELSKAMVFMDVRMPKFK 765
Query: 1335 WYHKVPVVEIK-------GHLDSMNVSLNQEDLNLL------FRILTENLCEGTEDLDKV 1381
Y K+P++ ++ G ++ + E + + F+I T ++ K+
Sbjct: 766 IYGKLPLISLRISDKKLQGIMELIESIPKPEPVTEVSAPVKSFQIQTSTSLGTSQISQKI 825
Query: 1382 KPRVQETGEIKEPLEISISQDVHDSKNT-------LTTGVEEIR---------SVDIINM 1425
P + E+ E ++ D+ + TGV+ IR SV++
Sbjct: 826 IPLL----ELPSVSEDDSEEEFFDAPCSPLEEPLQFPTGVKSIRTRKLQKQDCSVNMTTF 881
Query: 1426 LLNFEIKEVVVTLMKKSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFDFT 1485
+ FE+ +V++ + E+ VL LG E +++TYD+ A A+LK+ ++C ++
Sbjct: 882 KIRFEVPKVLIEFYHLVGDCELSVVEILVLGLGAEIEIRTYDLKANAFLKEFCLKCPEYL 941
Query: 1486 DSKGEPLHIINSSNVTDEPLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLHLE 1545
D +P++++ + + T E LL + KA+ + P+ K+ +++ Q +KV+F+SLD+ LH E
Sbjct: 942 DENKKPVYLVTTLDNTMEDLLTLEYVKAEKNVPDLKSTYNNVLQLIKVNFSSLDIHLHTE 1001
Query: 1546 ALLSFMDFLSSAAPFSEPSSSEKESELKPLVGESRSIAVKAVSSNIS-QKDVFDLKITAE 1604
ALL+ +++L + P SE EK + + E + +K ++ +S +D+ L+I AE
Sbjct: 1002 ALLNTINYLHNILPQSE----EKSAPVSTTETEDKGDVIKKLALKLSTNEDIITLQILAE 1057
Query: 1605 LNAFNVFVCDQKCNIADIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQSIHKKAVSI 1664
L+ +F+ DQKCNI++IKI G+D+ + ++P +T++ A+L++IIV++ D+ +I+KKAV I
Sbjct: 1058 LSCLQIFIQDQKCNISEIKIEGLDSEMIMRPSETEINAKLRNIIVLDSDITAIYKKAVYI 1117
Query: 1665 LGDEVFRFQLTLYPDATEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQT 1724
G EVF F++ Y DAT G AY DM+ VD +++ VGCI++V+V KF S+L F++NFQ
Sbjct: 1118 TGKEVFSFKMVSYMDATAGSAYTDMNVVDIQVNLIVGCIEVVFVTKFLYSILAFIDNFQA 1177
Query: 1725 AKEALSTATVQAAERAASSMKDLAQKSFRLLMDINLKAPVIIIPQSSVSPNAVIADLGLI 1784
AK+AL+ ATVQAA AA+ +K+LAQ+S R+ +DIN+KAPV++IPQS VS N +AD GLI
Sbjct: 1178 AKQALAEATVQAAGMAATGVKELAQRSSRMALDINIKAPVVVIPQSPVSENVFVADFGLI 1237
Query: 1785 RVENKFSLVPMEHYSLPPVIDKMNIELTQLKLSRTILQASLPQNDIEILKPVNMLLSIQR 1844
+ N F ++ S PPVID + I+L++++L R+ Q +++L P+N+ + ++R
Sbjct: 1238 TMTNTFHMITESQSSPPPVIDLITIKLSEMRLYRSRFINDAYQEVLDLLLPLNLEVVVER 1297
Query: 1845 NLAAAWYVQIPGMEIKGKLKPMQVALSEDDLTVLMKILLENLG-EASSQPSPTQSVQETV 1903
NL WY ++P + +LKPM+ LS++D+T + K L N+ E SP + +
Sbjct: 1298 NLCWEWYQEVPCFNVNAQLKPMEFILSQEDITTIFKTLHGNIWYEKDGSASPAVTKDQYS 1357
Query: 1904 RVRKVDVSSVPDHLKEQEDWTDSKLSMNQIV-----SLQFDFHFESLSIILYNNDINQES 1958
V ++ H T + + ++ +L F + L+++LY+ Q S
Sbjct: 1358 ATSGV-TTNASHHSGGATVVTAAVVEVHSRALLVKTTLNISFKTDDLTMVLYSPGPKQAS 1416
Query: 1959 GVAFHNDSFQLGELRLHLMASSGKMFKDGSMNVSVKLKTCTLDDLREGIERATSRMIDRK 2018
+ S +L E +L + S+ KM+ DGS S LK C LDD R +++AT RMI
Sbjct: 1417 FTDVRDPSLKLAEFKLENIISTLKMYTDGSTFSSFSLKNCILDDKRPHVKKATPRMIGLT 1476
Query: 2019 NDQDNNSSMIDISYKQDKNGSQIDAVLDKLYVCASVEFLMTVADFFIKAVPQSPENVAKE 2078
D M+DI Y++ ++G DAV ++Y+CASVEFL TVA+ F++A A E
Sbjct: 1477 VGFDKKD-MMDIKYRKVRDGCVTDAVFQEMYICASVEFLQTVANVFLEAYTTG---TAVE 1532
Query: 2079 TQILPRQTATGKVKIEKDDSVRPNMTLKAMITDPEVVFVASLTKADAPALTASFQCNLSL 2138
T + QT T K ++ +SV+ + +I +PE+VFVA +TK DAPAL + QC +
Sbjct: 1533 TSV---QTWTAKEEVPTQESVK--WEINVIIKNPEIVFVADMTKNDAPALVITTQCEICY 1587
Query: 2139 STSKLEQMMEASVRDLKVLACPFLREKRGKNITTVLQPCSLFMEKCTWASGKQNINIMVK 2198
+ M A+++DL+V ACPFL KR ITTVLQPC LF + + Q I++ VK
Sbjct: 1588 KGNLENSTMTAAIKDLQVRACPFLPVKRKGKITTVLQPCDLFYQTTQKGTDPQVIDMSVK 1647
Query: 2199 EFIIKISPIILNTVLTIMAALSPKTKEDGSKDTSKEMENLWGIKSINDYNTWFLGVDTAT 2258
+K+SP+I+NT++TI +AL TKE ++T+ +LW K WFL T
Sbjct: 1648 SLTLKVSPVIINTMITITSALYT-TKETIPEETASSTAHLWEKKDTKTLKMWFLEESNET 1706
Query: 2259 EITESFKGI--EHSLIEENCGVVVESIQVTLECGLGHRTVPLLLAESKFSGNIKNWTSLM 2316
E + + +I+ N ++SI + LE G+GHRTVP+LLA+S+FSG KNW+SL+
Sbjct: 1707 EKIAPTTELVPKGEMIKMN----IDSIFIVLEAGIGHRTVPMLLAKSRFSGEGKNWSSLI 1762
Query: 2317 AAVADVTLQVHYYNEIHAVWEPLIE-----RVEGKRQWNLRLDVKKNP---VQDKSLLPG 2368
+ L+VHYYNE+ VWEPL+E + E R WNL + +KK + +
Sbjct: 1763 NLHCQLELEVHYYNEMFGVWEPLLEPLEIDQTEDFRPWNLGIKMKKKAKMAIVESDPEEE 1822
Query: 2369 DDFIPEPQMAIHISSGNTMNITISKSCLNVFNNLAKGFSEG-TASTFDYSLKDRAPFTVK 2427
+ +PE + I S + +NIT+SK L + NNL K F+E T S+ D+ +KD APF +
Sbjct: 1823 NYKVPEYKTVISFHSKDQLNITLSKCGLVMLNNLVKAFTEAATGSSADF-VKDLAPFMIL 1881
Query: 2428 NAVGVPIKVKPNCNLRVMGFPEKSDIFDVDAGQNLELEYASMVPSSQGNLSILSRQESSF 2487
N++G+ I V P+ + V+ P + + G++L ++Y + N ++ S
Sbjct: 1882 NSLGLTISVSPSDSFSVLNIPMAKS-YVLKNGESLSMDYIRTKDNDHFNA--MTSLSSKL 1938
Query: 2488 FTLTIVPHGYTEVANIPVARPGRRLYNVRNPNASHSDSVLVQIDATEGNKVITLRSPLQI 2547
F + + P ++ IP+ + GRRLY VR+ + S++ QID EG+K +T+RSP+QI
Sbjct: 1939 FFILLTPVNHSTADKIPLTKVGRRLYTVRHRESGVERSIVCQIDTVEGSKKVTIRSPVQI 1998
Query: 2548 KNHFSIAFIIYKFVKNVKLLERIGIARPEEEFHVPLDSYRCQLFIQPAGILEHQYKESTT 2607
+NHFS+ +Y+ +G A PE EF++PL SYR +F++P +Q E
Sbjct: 1999 RNHFSVPLSVYEGDT------LLGTASPENEFNIPLGSYRSFIFLKPEDE-NYQMCEGID 2051
Query: 2608 YISWKEELHRSREVRCMLQCPSVEVSFLPLIVNTVALPDELSYICTHGED-WDVAYIIHL 2666
+ EE+ ++ +C S S ++N V D L+ + + ED WD+ YI+HL
Sbjct: 2052 F----EEIIKNDGALLKKKCRSKNPSKESFLINIVPEKDNLTSLSVYSEDGWDLPYIMHL 2107
Query: 2667 YPSLTLRNLLPYSLRYLLEGTAET-HELAEGSTADVLHSRISGEIMELVLVKYQGKNWNG 2725
+P + LRNLLPY + Y +EG + L+EG +A + +++ + L L+ Y +W
Sbjct: 2108 WPPILLRNLLPYKIAYYIEGIENSVFTLSEGHSAQICTAQLGKARLHLKLLDYLNHDWKS 2167
Query: 2726 HFRIRDTLPEFFPVCFSS-DSTEVTTVDLSVHVRRIGSRMVLSVFSPYWLINKTTRVLQY 2784
+ I+ + V F+ E T +D++VH+ + V++ SPYW++NKT R+LQY
Sbjct: 2168 EYHIKPNQQDISFVSFTCVTEMEKTDLDIAVHMTYNTGQTVVAFHSPYWMVNKTGRMLQY 2227
Query: 2785 RSEDIHVKHPADFRDIILFSFKKKNIFTKNKVQLKISTSAWSSSFSLDTVGSYGCVKCPA 2844
+++ IH KHP +++ +LFSF+ + F NKVQL ++ S S+ FS+DTVGS+G VKC
Sbjct: 2228 KADGIHRKHPPNYKKPVLFSFQPNHFFNNNKVQLMVTDSELSNQFSIDTVGSHGAVKCKG 2287
Query: 2845 NNMEYLVGVSIKMSSFNLSRIVTLTPFCTIANKSSLELEVGEIASDGSMPTNKWNYIASS 2904
M+Y VGV+I +SSFN++RIVT TPF I NKS + V E +D KW +
Sbjct: 2288 LKMDYQVGVTIDLSSFNITRIVTFTPFYMIKNKSKYHISVAEEGND------KWLSLDLE 2341
Query: 2905 ECLPFWPESLSGKLCVRVVGCEGSSKPFFYNRQDNGTLLSLEDLNGGILVDVNTAEHSTV 2964
+C+PFWPE S KL ++V E K ++N+Q+N LL L++ GGI+ +VN AEHSTV
Sbjct: 2342 QCIPFWPEYASSKLLIQVERSEDPPKRIYFNKQENCILLRLDNELGGIIAEVNLAEHSTV 2401
Query: 2965 ITFSDYHEGSAPALIMNHTPWDILTYKQSGSPE-EMVLLPRQARLFAWADPTGTRKLTWT 3023
ITF DYH+G+A L++NHT +++ Y QS E E L P +A + WADP G+R+L W
Sbjct: 2402 ITFLDYHDGAATFLLINHTKNELVQYNQSSLSEIEDSLPPGKAVFYTWADPVGSRRLKWR 2461
Query: 3024 YAANVGEHDLLKDGCGQFPYDANIQ-IHWVSFLDGRQRVLLFTDDVALVSKALQAEEMEQ 3082
+ GE D P D + I+ VSF +G QR++LFT+D + ++E+ E
Sbjct: 2462 CRKSHGEVTQKDDM--MMPIDLGEKTIYLVSFFEGLQRIILFTEDPRVFKVTYESEKAEL 2519
Query: 3083 ADYEITLSLHSLGLSLVNNESKQEVSYIGITSSGVVWEVKPKQK--WKPFSQKQIILLEQ 3140
A+ EI ++L +G+SLVNN +KQEV+YIGITSS VVWE KPK+K WKP S K LE+
Sbjct: 2520 AEQEIAVALQDVGISLVNNYTKQEVAYIGITSSDVVWETKPKKKARWKPMSVKHTEKLER 2579
Query: 3141 SYQKHQISR--DHGWIKLDNNFEVNFDKDPMEMRL--PIRSPIKRDFLSGIQIEFKQSSH 3196
++++ S + I+LD N V M++ P ++R++L +++E+ S+H
Sbjct: 2580 EFKEYTESSPSEDKVIQLDTNVPVRLTPTGHNMKILQPHVIALRRNYLPALKVEYNTSAH 2639
Query: 3197 QRSLRARLYWLQVDNQLPGAMFPVVFHPVAPPKSIALDSEPKPFIDVSVITRFNEYSKVL 3256
Q S R ++Y +Q+ NQ+ GA+FP VF+PV PPKS+ +DS PKPF DVS++ R +S++
Sbjct: 2640 QSSFRIQIYRIQIQNQIHGAVFPFVFYPVKPPKSVTMDSAPKPFTDVSIVMRSAGHSQIS 2699
Query: 3257 QFKYFMVLIQEMALKIDQGFLGAIIALFTPTTDPEAERRRTKLIQQDIDALNAELMETSM 3316
+ KYF VLIQEM L++D GF+ A+ L T E +L +DI+A E S+
Sbjct: 2700 RIKYFKVLIQEMDLRLDLGFIYALTDLMTEAE--VTENTEVELFHKDIEAFKEEYKTASL 2757
Query: 3317 TDMSILSFFEHFHISPVKLHLSLSLGSGGEESDKEKQE--MFAVHSVNLLLKSIGATLTD 3374
D S +S +E+FHISP+KLHLS+SL SG EE+ KQ + VHS+NLLLKSIGATLTD
Sbjct: 2758 VDQSQVSLYEYFHISPIKLHLSVSLSSGREEAKDSKQNGGLIPVHSLNLLLKSIGATLTD 2817
Query: 3375 VDDLIFKLAYYEIRYQFYKRDQLIWSVVRHYSEQFLKQMYVLVLGLDVLGNPFGLIRGLS 3434
V D++FKLA++E+ YQF+ L V+RHYS+Q +KQMYVL+LGLDVLGNPFGLIR S
Sbjct: 2818 VQDVVFKLAFFELNYQFHTTSDLQSEVIRHYSKQAIKQMYVLILGLDVLGNPFGLIREFS 2877
Query: 3435 EGVEALFYEPFQGAVQGPEEFAEGLVIGVRSLFGHTVGGAAGVVSRITGSVGKGLAAITM 3494
EGVEA FYEP+QGA+QGPEEF EG+ +G+++L G VGG AG S+ITG++ KG+AA+TM
Sbjct: 2878 EGVEAFFYEPYQGAIQGPEEFVEGMALGLKALVGGAVGGLAGAASKITGAMAKGVAAMTM 2937
Query: 3495 DKEYQQKRREELSRQPRDFGDSLARGGKGFLRGVVGGVTGIITKPVEGAKKEGAAGFFKG 3554
D++YQQKRRE +++QP F + + RGGKG + G V G+TGI+TKP++GA+K GAAGFFKG
Sbjct: 2938 DEDYQQKRREAMNKQPAGFREGITRGGKGLVSGFVSGITGIVTKPIKGAQKGGAAGFFKG 2997
Query: 3555 IGKGLVGAVARPTGGIVDMASSTFQGIQRAAESTEEVSSLRPPRLIHEDGIIRPYDRQES 3614
+GKGLVGAVARPTGGI+DMASSTFQGI+RA E T EV SLRPPR +EDG+IRPY ++
Sbjct: 2998 VGKGLVGAVARPTGGIIDMASSTFQGIKRATE-TSEVESLRPPRFFNEDGVIRPYRLRDG 3056
Query: 3615 EGSDLLE 3621
G+ +L+
Sbjct: 3057 TGNQMLQ 3063
Score = 1131 bits (2926), Expect = 0.0
Identities = 618/1396 (44%), Positives = 889/1396 (63%), Gaps = 82/1396 (5%)
Query: 1 MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAG 60
MV ESVV D+LNRFLGDYV +L+ SQL LGIW G VAL NLQIKENALS+LDVPFKVK G
Sbjct: 1 MVFESVVVDVLNRFLGDYVVDLDTSQLSLGIWKGAVALKNLQIKENALSQLDVPFKVKVG 60
Query: 61 QIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEE 120
I L L IPWKNLY + V A LE +YLL+VP + IKYD +KEEK L + KQ+EL RIEE
Sbjct: 61 HIGNLKLIIPWKNLYTQPVEAVLEEIYLLIVPSSRIKYDPLKEEKQLMEAKQQELKRIEE 120
Query: 121 ALQKAAEKGTHSGEFIYGLENFVYKDIKPGRKRKKHKKHFKKPFKGLDRSKDKPKEAKKD 180
A QK ++ H E K+D
Sbjct: 121 AKQKVVDQEQHLPE-------------------------------------------KQD 137
Query: 181 TFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLGELSLLTANEHWTPCILN 240
TF EKL TQ+IKN+QVKI+ IHI+YEDD+T+ +PLSFG++L LS+ T +++W PC+ +
Sbjct: 138 TFAEKLVTQIIKNLQVKISSIHIRYEDDITNRDKPLSFGISLQNLSMQTTDQYWVPCLHD 197
Query: 241 EADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILDQLKNEILTSGNIPPNYQYIFQPIS 300
E +K++ KLIRLD+L AYWNV M Y + LD LKN I+ +P Y ++F+PIS
Sbjct: 198 ETEKLVRKLIRLDNLFAYWNVKSQMFYLSDYDNSLDDLKNGIVNENIVPEGYDFVFRPIS 257
Query: 301 ASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKPQYLSMIDLLESVDYMVRNAPYRKY 360
A+AKL MN ++ + PK++ IE+ NIAIE KPQY S+++LLESVD M +N PYRK+
Sbjct: 258 ANAKLVMNRRSDFDFSAPKINLEIELHNIAIEFNKPQYFSIMELLESVDMMAQNLPYRKF 317
Query: 361 KPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIKKHRQLLKSYKIAYKNKLTQSK 420
KP +PLH + R WW YAI VLEV++ MWSW +I+KHRQ +K YK YK KLT K
Sbjct: 318 KPDVPLHHHAREWWAYAIHGVLEVNVCPRLWMWSWKHIRKHRQKVKQYKELYKKKLTSKK 377
Query: 421 VSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKSADTGEKRGGWFSGLWGK 480
E+ +++LEKTLDVFNI +ARQ A+VEV ++G K+ K+ E GWFS LW
Sbjct: 378 PPGELLVSLEELEKTLDVFNITIARQTAEVEVKKAGYKIYKEGVKDPEDNKGWFSWLWSW 437
Query: 481 KESKKKDEE-SLIPETIDDLMTPEEKDKLFTAIGYSESTHNLTLPKQYVAHIMTLKLVST 539
E +++ + PET+++++TPEEK L+ AIGYSE+ + TL K + A + L S
Sbjct: 438 SEQNTNEQQPDVQPETLEEMLTPEEKALLYEAIGYSETAVDPTLLKTFEALKFFVHLKSM 497
Query: 540 SVTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVEAKLEHWYITGLRQQDIVPSLVAS 599
S+ +REN PE++ I I T + QRPGAQA+K E K++ ++ITGL P L++S
Sbjct: 498 SIVLRENHQKPELVDIVIEEFSTLIVQRPGAQAIKFETKIDSFHITGLPDNSEKPRLLSS 557
Query: 600 IGDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIYDAKTVNAVVEFFQSNKGLDLEQI 659
+ D SL +I FE NP D Q I++++P+E+IYDA+TVN++VEFF+ K + L Q+
Sbjct: 558 L-DDAMSLFQITFEINPLDETVSQRCIIEAEPLEIIYDARTVNSIVEFFRPPKEVHLAQL 616
Query: 660 TSATLMKLEEIKERTATGLTHIIETRKVLDLRINLKPSYLVVPQTGFHHEKSDLLILDFG 719
T+ATL KLEE + +TATGL +IIET+KVLDL+INLK SY++VPQ G S+LL+LD G
Sbjct: 617 TAATLTKLEEFRSKTATGLLYIIETQKVLDLKINLKASYIIVPQDGIFSPTSNLLLLDLG 676
Query: 720 TFQLNSKDQGL---QKTTNSSLEEIMDKAYDKFDVEIKNVQLLFARAEETWKKCRFQHPS 776
++ SK + K ++L+EIMD+AYD FD+++ +VQLL++R + W++ R S
Sbjct: 677 HLKVTSKSRSELPDVKQGEANLKEIMDRAYDSFDIQLTSVQLLYSRVGDNWREARKLSVS 736
Query: 777 TMHILQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVRISDQKMKDVLYLMNSIPLPQ 836
T HIL PM ++EL+KAMV D+RM +FK+ G LPL+ +RISD+K++ ++ L+ SIP P+
Sbjct: 737 TQHILVPMHFNLELSKAMVFMDVRMPKFKIYGKLPLISLRISDKKLQGIMELIESIPKPE 796
Query: 837 KSSAQSPERQVSS-IPIISGGTKGLLGTSLLLDTV----------ESESDDEYFDAEDGE 885
P +VS+ + T LGTS + + E +S++E+FDA
Sbjct: 797 ------PVTEVSAPVKSFQIQTSTSLGTSQISQKIIPLLELPSVSEDDSEEEFFDAPCSP 850
Query: 886 -------PQTCKSMKGSELKKAAEVPNEELINLLLKFEIKEVILEFTKQQKE-EDTILVF 937
P KS++ +L+K + + + ++FE+ +V++EF + E +++
Sbjct: 851 LEEPLQFPTGVKSIRTRKLQK--QDCSVNMTTFKIRFEVPKVLIEFYHLVGDCELSVVEI 908
Query: 938 NVTQLGTEATMRTFDLTVVSYLKKISLDYHEIEGSKRKPLHLISSSDKPGLDLLKVEYIK 997
V LG E +RT+DL ++LK+ L E +KP++L+++ D DLL +EY+K
Sbjct: 909 LVLGLGAEIEIRTYDLKANAFLKEFCLKCPEYLDENKKPVYLVTTLDNTMEDLLTLEYVK 968
Query: 998 ADKNGPSFQTAFGKTEQTVKVAFSSLNLLLQTQALVASINYLTTIIP-SDDQSISVAKEV 1056
A+KN P ++ + Q +KV FSSL++ L T+AL+ +INYL I+P S+++S V+
Sbjct: 969 AEKNVPDLKSTYNNVLQLIKVNFSSLDIHLHTEALLNTINYLHNILPQSEEKSAPVS--- 1025
Query: 1057 QISTEKQQKNSTLPK-AIVSSRDSDIIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSS 1115
+TE + K + K A+ S + DII ++ A+L+ + + ++K NI+EIKI+GLDS
Sbjct: 1026 --TTETEDKGDVIKKLALKLSTNEDIITLQILAELSCLQIFIQDQKCNISEIKIEGLDSE 1083
Query: 1116 LSLQSRKQSLFARLENIIVTDVDPKTVHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMS 1175
+ ++ + + A+L NIIV D D ++KKAV I G EVF F + Y DAT G YTDM+
Sbjct: 1084 MIMRPSETEINAKLRNIIVLDSDITAIYKKAVYITGKEVFSFKMVSYMDATAGSAYTDMN 1143
Query: 1176 KVDGVLSLNVGCIQIVYLHKFLMSLLNFLNNFQTAKESLSAATAQAAERAATSVKDLAQR 1235
VD ++L VGCI++V++ KFL S+L F++NFQ AK++L+ AT QAA AAT VK+LAQR
Sbjct: 1144 VVDIQVNLIVGCIEVVFVTKFLYSILAFIDNFQAAKQALAEATVQAAGMAATGVKELAQR 1203
Query: 1236 SFRVSINIDLKAPVIVIPQSSISTNAVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQ 1295
S R++++I++KAPV+VIPQS +S N V D GLI + N F ++++ PPVID + ++
Sbjct: 1204 SSRMALDINIKAPVVVIPQSPVSENVFVADFGLITMTNTFHMITESQSSPPPVIDLITIK 1263
Query: 1296 LTKLTLYRTVIQPGIYHPDIQLLHPINLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSL 1355
L+++ LYR+ Y + LL P+NLE +V RNL WY +VP + L M L
Sbjct: 1264 LSEMRLYRSRFINDAYQEVLDLLLPLNLEVVVERNLCWEWYQEVPCFNVNAQLKPMEFIL 1323
Query: 1356 NQEDLNLLFRILTENL 1371
+QED+ +F+ L N+
Sbjct: 1324 SQEDITTIFKTLHGNI 1339
Score = 54.7 bits (130), Expect = 2e-06
Identities = 82/394 (20%), Positives = 175/394 (44%), Gaps = 57/394 (14%)
Query: 1560 FSEPSSSEKESELKP------LVGESRSIAVKAVSSNISQKD-----VFD-LKITAELNA 1607
+SE +++E++ +++P L E +++ +A+ + + D F+ LK L +
Sbjct: 437 WSEQNTNEQQPDVQPETLEEMLTPEEKALLYEAIGYSETAVDPTLLKTFEALKFFVHLKS 496
Query: 1608 FNVFVCD--QKCNIADIKIHGMDASISVKPKQTDVF--ARLKDIIVMNVDLQSIHKKAVS 1663
++ + + QK + DI I I +P + ++ + + S + +S
Sbjct: 497 MSIVLRENHQKPELVDIVIEEFSTLIVQRPGAQAIKFETKIDSFHITGLPDNSEKPRLLS 556
Query: 1664 ILGDEVFRFQLTLYPDATEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQ 1723
L D + FQ+T + + V + + ++I+Y + S++ F F+
Sbjct: 557 SLDDAMSLFQITFEINPLD-------ETVSQRCIIEAEPLEIIYDARTVNSIVEF---FR 606
Query: 1724 TAKEA----LSTATVQAAE----RAASSMKDLAQKSFRLLMDINLKAPVIIIPQSSV--- 1772
KE L+ AT+ E + A+ + + + L + INLKA II+PQ +
Sbjct: 607 PPKEVHLAQLTAATLTKLEEFRSKTATGLLYIIETQKVLDLKINLKASYIIVPQDGIFSP 666
Query: 1773 SPNAVIADLGLIRVENK----FSLVPMEHYSLPPVIDK----MNIELTQLKLSRTIL--- 1821
+ N ++ DLG ++V +K V +L ++D+ +I+LT ++L + +
Sbjct: 667 TSNLLLLDLGHLKVTSKSRSELPDVKQGEANLKEIMDRAYDSFDIQLTSVQLLYSRVGDN 726
Query: 1822 ---QASLPQNDIEILKPVNMLLSIQRNLAAAWYVQIPGMEIKGKLKPMQVALSEDDLTVL 1878
L + IL P++ L + + + V++P +I GKL + + +S+ L +
Sbjct: 727 WREARKLSVSTQHILVPMHFNLELSKAM-VFMDVRMPKFKIYGKLPLISLRISDKKLQGI 785
Query: 1879 MKILLENLGEASSQPSPTQSVQETVRVRKVDVSS 1912
M+++ E+ +P P V V+ ++ S+
Sbjct: 786 MELI-----ESIPKPEPVTEVSAPVKSFQIQTST 814
>gi|66346672 vacuolar protein sorting 13A isoform C [Homo sapiens]
Length = 3135
Score = 1649 bits (4269), Expect = 0.0
Identities = 991/2609 (37%), Positives = 1517/2609 (58%), Gaps = 187/2609 (7%)
Query: 1188 IQIVYLHKFLMSLLNFLNNFQTAKE----SLSAATAQAAE----RAATSVKDLAQRSFRV 1239
++I+Y + + S++ F F+ KE L+AAT E + AT + + + +
Sbjct: 589 LEIIYDARTVNSIVEF---FRPPKEVHLAQLTAATLTKLEEFRSKTATGLLYIIETQKVL 645
Query: 1240 SINIDLKAPVIVIPQSSI---STNAVVVDLGLIRV----HNQFSLVSDEDYLNPPVIDR- 1291
+ I+LKA I++PQ I ++N +++DLG ++V ++ V + ++DR
Sbjct: 646 DLKINLKASYIIVPQDGIFSPTSNLLLLDLGHLKVTSKSRSELPDVKQGEANLKEIMDRA 705
Query: 1292 ---MDVQLTKLTL--------YRTVIQPGIYHPDIQLLHPINLE------FLVNRNLAAS 1334
D+QLT + L +R + + I + NLE F+ R
Sbjct: 706 YDSFDIQLTSVQLLYSRVGDNWREARKLSVSTQHILVPMHFNLELSKAMVFMDVRMPKFK 765
Query: 1335 WYHKVPVVEIK-------GHLDSMNVSLNQEDLNLL------FRILTENLCEGTEDLDKV 1381
Y K+P++ ++ G ++ + E + + F+I T ++ K+
Sbjct: 766 IYGKLPLISLRISDKKLQGIMELIESIPKPEPVTEVSAPVKSFQIQTSTSLGTSQISQKI 825
Query: 1382 KPRVQETGEIKEPLEISISQDVHDSKNT-------LTTGVEEIR---------SVDIINM 1425
P + E+ E ++ D+ + TGV+ IR SV++
Sbjct: 826 IPLL----ELPSVSEDDSEEEFFDAPCSPLEEPLQFPTGVKSIRTRKLQKQDCSVNMTTF 881
Query: 1426 LLNFEIKEVVVTLMKKSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFDFT 1485
+ FE+ +V++ + E+ VL LG E +++TYD+ A A+LK+ ++C ++
Sbjct: 882 KIRFEVPKVLIEFYHLVGDCELSVVEILVLGLGAEIEIRTYDLKANAFLKEFCLKCPEYL 941
Query: 1486 DSKGEPLHIINSSNVTDEPLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLHLE 1545
D +P++++ + + T E LL + KA+ + P+ K+ +++ Q +KV+F+SLD+ LH E
Sbjct: 942 DENKKPVYLVTTLDNTMEDLLTLEYVKAEKNVPDLKSTYNNVLQLIKVNFSSLDIHLHTE 1001
Query: 1546 ALLSFMDFLSSAAPFSEPSSSEKESELKPLVGESRSIAVKAVSSNISQKDVFDLKITAEL 1605
ALL+ +++L + P SE S A S +D D+
Sbjct: 1002 ALLNTINYLHNILPQSEEKS--------------------APVSTTETEDKGDV------ 1035
Query: 1606 NAFNVFVCDQKCNIADIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQSIHKKAVSIL 1665
IK G+D+ + ++P +T++ A+L++IIV++ D+ +I+KKAV I
Sbjct: 1036 ----------------IKKLGLDSEMIMRPSETEINAKLRNIIVLDSDITAIYKKAVYIT 1079
Query: 1666 GDEVFRFQLTLYPDATEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQTA 1725
G EVF F++ Y DAT G AY DM+ VD +++ VGCI++V+V KF S+L F++NFQ A
Sbjct: 1080 GKEVFSFKMVSYMDATAGSAYTDMNVVDIQVNLIVGCIEVVFVTKFLYSILAFIDNFQAA 1139
Query: 1726 KEALSTATVQAAERAASSMKDLAQKSFRLLMDINLKAPVIIIPQSSVSPNAVIADLGLIR 1785
K+AL+ ATVQAA AA+ +K+LAQ+S R+ +DIN+KAPV++IPQS VS N +AD GLI
Sbjct: 1140 KQALAEATVQAAGMAATGVKELAQRSSRMALDINIKAPVVVIPQSPVSENVFVADFGLIT 1199
Query: 1786 VENKFSLVPMEHYSLPPVIDKMNIELTQLKLSRTILQASLPQNDIEILKPVNMLLSIQRN 1845
+ N F ++ S PPVID + I+L++++L R+ Q +++L P+N+ + ++RN
Sbjct: 1200 MTNTFHMITESQSSPPPVIDLITIKLSEMRLYRSRFINDAYQEVLDLLLPLNLEVVVERN 1259
Query: 1846 LAAAWYVQIPGMEIKGKLKPMQVALSEDDLTVLMKILLENLG-EASSQPSPTQSVQETVR 1904
L WY ++P + +LKPM+ LS++D+T + K L N+ E SP + +
Sbjct: 1260 LCWEWYQEVPCFNVNAQLKPMEFILSQEDITTIFKTLHGNIWYEKDGSASPAVTKDQYSA 1319
Query: 1905 VRKVDVSSVPDHLKEQEDWTDSKLSMNQIV-----SLQFDFHFESLSIILYNNDINQESG 1959
V ++ H T + + ++ +L F + L+++LY+ Q S
Sbjct: 1320 TSGV-TTNASHHSGGATVVTAAVVEVHSRALLVKTTLNISFKTDDLTMVLYSPGPKQASF 1378
Query: 1960 VAFHNDSFQLGELRLHLMASSGKMFKDGSMNVSVKLKTCTLDDLREGIERATSRMIDRKN 2019
+ S +L E +L + S+ KM+ DGS S LK C LDD R +++AT RMI
Sbjct: 1379 TDVRDPSLKLAEFKLENIISTLKMYTDGSTFSSFSLKNCILDDKRPHVKKATPRMIGLTV 1438
Query: 2020 DQDNNSSMIDISYKQDKNGSQIDAVLDKLYVCASVEFLMTVADFFIKAVPQSPENVAKET 2079
D M+DI Y++ ++G DAV ++Y+CASVEFL TVA+ F++A A ET
Sbjct: 1439 GFDKKD-MMDIKYRKVRDGCVTDAVFQEMYICASVEFLQTVANVFLEAYTTG---TAVET 1494
Query: 2080 QILPRQTATGKVKIEKDDSVRPNMTLKAMITDPEVVFVASLTKADAPALTASFQCNLSLS 2139
+ QT T K ++ +SV+ + +I +PE+VFVA +TK DAPAL + QC +
Sbjct: 1495 SV---QTWTAKEEVPTQESVK--WEINVIIKNPEIVFVADMTKNDAPALVITTQCEICYK 1549
Query: 2140 TSKLEQMMEASVRDLKVLACPFLREKRGKNITTVLQPCSLFMEKCTWASGKQNINIMVKE 2199
+ M A+++DL+V ACPFL KR ITTVLQPC LF + + Q I++ VK
Sbjct: 1550 GNLENSTMTAAIKDLQVRACPFLPVKRKGKITTVLQPCDLFYQTTQKGTDPQVIDMSVKS 1609
Query: 2200 FIIKISPIILNTVLTIMAALSPKTKEDGSKDTSKEMENLWGIKSINDYNTWFLGVDTATE 2259
+K+SP+I+NT++TI +AL TKE ++T+ +LW K WFL TE
Sbjct: 1610 LTLKVSPVIINTMITITSALYT-TKETIPEETASSTAHLWEKKDTKTLKMWFLEESNETE 1668
Query: 2260 ITESFKGI--EHSLIEENCGVVVESIQVTLECGLGHRTVPLLLAESKFSGNIKNWTSLMA 2317
+ + +I+ N ++SI + LE G+GHRTVP+LLA+S+FSG KNW+SL+
Sbjct: 1669 KIAPTTELVPKGEMIKMN----IDSIFIVLEAGIGHRTVPMLLAKSRFSGEGKNWSSLIN 1724
Query: 2318 AVADVTLQVHYYNEIHAVWEPLIE-----RVEGKRQWNLRLDVKKNP---VQDKSLLPGD 2369
+ L+VHYYNE+ VWEPL+E + E R WNL + +KK + + +
Sbjct: 1725 LHCQLELEVHYYNEMFGVWEPLLEPLEIDQTEDFRPWNLGIKMKKKAKMAIVESDPEEEN 1784
Query: 2370 DFIPEPQMAIHISSGNTMNITISKSCLNVFNNLAKGFSEG-TASTFDYSLKDRAPFTVKN 2428
+PE + I S + +NIT+SK L + NNL K F+E T S+ D+ +KD APF + N
Sbjct: 1785 YKVPEYKTVISFHSKDQLNITLSKCGLVMLNNLVKAFTEAATGSSADF-VKDLAPFMILN 1843
Query: 2429 AVGVPIKVKPNCNLRVMGFPEKSDIFDVDAGQNLELEYASMVPSSQGNLSILSRQESSFF 2488
++G+ I V P+ + V+ P + + G++L ++Y + N ++ S F
Sbjct: 1844 SLGLTISVSPSDSFSVLNIPMAKS-YVLKNGESLSMDYIRTKDNDHFNA--MTSLSSKLF 1900
Query: 2489 TLTIVPHGYTEVANIPVARPGRRLYNVRNPNASHSDSVLVQIDATEGNKVITLRSPLQIK 2548
+ + P ++ IP+ + GRRLY VR+ + S++ QID EG+K +T+RSP+QI+
Sbjct: 1901 FILLTPVNHSTADKIPLTKVGRRLYTVRHRESGVERSIVCQIDTVEGSKKVTIRSPVQIR 1960
Query: 2549 NHFSIAFIIYKFVKNVKLLERIGIARPEEEFHVPLDSYRCQLFIQPAGILEHQYKESTTY 2608
NHFS+ +Y+ +G A PE EF++PL SYR +F++P +Q E +
Sbjct: 1961 NHFSVPLSVYEGDT------LLGTASPENEFNIPLGSYRSFIFLKPEDE-NYQMCEGIDF 2013
Query: 2609 ISWKEELHRSREVRCMLQCPSVEVSFLPLIVNTVALPDELSYICTHGED-WDVAYIIHLY 2667
EE+ ++ +C S S ++N V D L+ + + ED WD+ YI+HL+
Sbjct: 2014 ----EEIIKNDGALLKKKCRSKNPSKESFLINIVPEKDNLTSLSVYSEDGWDLPYIMHLW 2069
Query: 2668 PSLTLRNLLPYSLRYLLEGTAET-HELAEGSTADVLHSRISGEIMELVLVKYQGKNWNGH 2726
P + LRNLLPY + Y +EG + L+EG +A + +++ + L L+ Y +W
Sbjct: 2070 PPILLRNLLPYKIAYYIEGIENSVFTLSEGHSAQICTAQLGKARLHLKLLDYLNHDWKSE 2129
Query: 2727 FRIRDTLPEFFPVCFSS-DSTEVTTVDLSVHVRRIGSRMVLSVFSPYWLINKTTRVLQYR 2785
+ I+ + V F+ E T +D++VH+ + V++ SPYW++NKT R+LQY+
Sbjct: 2130 YHIKPNQQDISFVSFTCVTEMEKTDLDIAVHMTYNTGQTVVAFHSPYWMVNKTGRMLQYK 2189
Query: 2786 SEDIHVKHPADFRDIILFSFKKKNIFTKNKVQLKISTSAWSSSFSLDTVGSYGCVKCPAN 2845
++ IH KHP +++ +LFSF+ + F NKVQL ++ S S+ FS+DTVGS+G VKC
Sbjct: 2190 ADGIHRKHPPNYKKPVLFSFQPNHFFNNNKVQLMVTDSELSNQFSIDTVGSHGAVKCKGL 2249
Query: 2846 NMEYLVGVSIKMSSFNLSRIVTLTPFCTIANKSSLELEVGEIASDGSMPTNKWNYIASSE 2905
M+Y VGV+I +SSFN++RIVT TPF I NKS + V E +D KW + +
Sbjct: 2250 KMDYQVGVTIDLSSFNITRIVTFTPFYMIKNKSKYHISVAEEGND------KWLSLDLEQ 2303
Query: 2906 CLPFWPESLSGKLCVRVVGCEGSSKPFFYNRQDNGTLLSLEDLNGGILVDVNTAEHSTVI 2965
C+PFWPE S KL ++V E K ++N+Q+N LL L++ GGI+ +VN AEHSTVI
Sbjct: 2304 CIPFWPEYASSKLLIQVERSEDPPKRIYFNKQENCILLRLDNELGGIIAEVNLAEHSTVI 2363
Query: 2966 TFSDYHEGSAPALIMNHTPWDILTYKQSGSPE-EMVLLPRQARLFAWADPTGTRKLTWTY 3024
TF DYH+G+A L++NHT +++ Y QS E E L P +A + WADP G+R+L W
Sbjct: 2364 TFLDYHDGAATFLLINHTKNELVQYNQSSLSEIEDSLPPGKAVFYTWADPVGSRRLKWRC 2423
Query: 3025 AANVGEHDLLKDGCGQFPYDANIQ-IHWVSFLDGRQRVLLFTDDVALVSKALQAEEMEQA 3083
+ GE D P D + I+ VSF +G QR++LFT+D + ++E+ E A
Sbjct: 2424 RKSHGEVTQKDDM--MMPIDLGEKTIYLVSFFEGLQRIILFTEDPRVFKVTYESEKAELA 2481
Query: 3084 DYEITLSLHSLGLSLVNNESKQEVSYIGITSSGVVWEVKPKQK--WKPFSQKQIILLEQS 3141
+ EI ++L +G+SLVNN +KQEV+YIGITSS VVWE KPK+K WKP S K LE+
Sbjct: 2482 EQEIAVALQDVGISLVNNYTKQEVAYIGITSSDVVWETKPKKKARWKPMSVKHTEKLERE 2541
Query: 3142 YQKHQISR--DHGWIKLDNNFEVNFDKDPMEMRL--PIRSPIKRDFLSGIQIEFKQSSHQ 3197
++++ S + I+LD N V M++ P ++R++L +++E+ S+HQ
Sbjct: 2542 FKEYTESSPSEDKVIQLDTNVPVRLTPTGHNMKILQPHVIALRRNYLPALKVEYNTSAHQ 2601
Query: 3198 RSLRARLYWLQVDNQLPGAMFPVVFHPVAPPKSIALDSEPKPFIDVSVITRFNEYSKVLQ 3257
S R ++Y +Q+ NQ+ GA+FP VF+PV PPKS+ +DS PKPF DVS++ R +S++ +
Sbjct: 2602 SSFRIQIYRIQIQNQIHGAVFPFVFYPVKPPKSVTMDSAPKPFTDVSIVMRSAGHSQISR 2661
Query: 3258 FKYFMVLIQEMALKIDQGFLGAIIALFTPTTDPEAERRRTKLIQQDIDALNAELMETSMT 3317
KYF VLIQEM L++D GF+ A+ L T E +L +DI+A E S+
Sbjct: 2662 IKYFKVLIQEMDLRLDLGFIYALTDLMTEAE--VTENTEVELFHKDIEAFKEEYKTASLV 2719
Query: 3318 DMSILSFFEHFHISPVKLHLSLSLGSGGEESDKEKQE--MFAVHSVNLLLKSIGATLTDV 3375
D S +S +E+FHISP+KLHLS+SL SG EE+ KQ + VHS+NLLLKSIGATLTDV
Sbjct: 2720 DQSQVSLYEYFHISPIKLHLSVSLSSGREEAKDSKQNGGLIPVHSLNLLLKSIGATLTDV 2779
Query: 3376 DDLIFKLAYYEIRYQFYKRDQLIWSVVRHYSEQFLKQMYVLVLGLDVLGNPFGLIRGLSE 3435
D++FKLA++E+ YQF+ L V+RHYS+Q +KQMYVL+LGLDVLGNPFGLIR SE
Sbjct: 2780 QDVVFKLAFFELNYQFHTTSDLQSEVIRHYSKQAIKQMYVLILGLDVLGNPFGLIREFSE 2839
Query: 3436 GVEALFYEPFQGAVQGPEEFAEGLVIGVRSLFGHTVGGAAGVVSRITGSVGKGLAAITMD 3495
GVEA FYEP+QGA+QGPEEF EG+ +G+++L G VGG AG S+ITG++ KG+AA+TMD
Sbjct: 2840 GVEAFFYEPYQGAIQGPEEFVEGMALGLKALVGGAVGGLAGAASKITGAMAKGVAAMTMD 2899
Query: 3496 KEYQQKRREELSRQPRDFGDSLARGGKGFLRGVVGGVTGIITKPVEGAKKEGAAGFFKGI 3555
++YQQKRRE +++QP F + + RGGKG + G V G+TGI+TKP++GA+K GAAGFFKG+
Sbjct: 2900 EDYQQKRREAMNKQPAGFREGITRGGKGLVSGFVSGITGIVTKPIKGAQKGGAAGFFKGV 2959
Query: 3556 GKGLVGAVARPTGGIVDMASSTFQGIQRAAESTEEVSSLRPPRLIHEDGIIRPYDRQESE 3615
GKGLVGAVARPTGGI+DMASSTFQGI+RA E T EV SLRPPR +EDG+IRPY ++
Sbjct: 2960 GKGLVGAVARPTGGIIDMASSTFQGIKRATE-TSEVESLRPPRFFNEDGVIRPYRLRDGT 3018
Query: 3616 GSDLLENHIKKLEGETYRYHCAIPGSKKTILMVTNRRVLCIKEVEILGLMCVDWQCPFED 3675
G+ +L+ ++ Y+Y + +K +LM+T R VL + + L C +WQ F++
Sbjct: 3019 GNQMLQ-VMENGRFAKYKYFTHVMINKTDMLMITRRGVLFVTKGTFGQLTC-EWQYSFDE 3076
Query: 3676 FVFPP-SVSENVLKISVKE--QGLFHKKD 3701
F P V L+I KE + +FH ++
Sbjct: 3077 FTKEPFIVHGRRLRIEAKERVKSVFHARE 3105
Score = 1090 bits (2820), Expect = 0.0
Identities = 603/1394 (43%), Positives = 863/1394 (61%), Gaps = 117/1394 (8%)
Query: 1 MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAG 60
MV ESVV D+LNRFLGDYV +L+ SQL LGIW G VAL NLQIKENALS+LDVPFKVK G
Sbjct: 1 MVFESVVVDVLNRFLGDYVVDLDTSQLSLGIWKGAVALKNLQIKENALSQLDVPFKVKVG 60
Query: 61 QIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEE 120
I L L IPWKNLY + V A LE +YLL+VP + IKYD +KEEK L + KQ+EL RIEE
Sbjct: 61 HIGNLKLIIPWKNLYTQPVEAVLEEIYLLIVPSSRIKYDPLKEEKQLMEAKQQELKRIEE 120
Query: 121 ALQKAAEKGTHSGEFIYGLENFVYKDIKPGRKRKKHKKHFKKPFKGLDRSKDKPKEAKKD 180
A QK ++ H E K+D
Sbjct: 121 AKQKVVDQEQHLPE-------------------------------------------KQD 137
Query: 181 TFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLGELSLLTANEHWTPCILN 240
TF EKL TQ+IKN+QVKI+ IHI+YEDD+T+ +PLSFG++L LS+ T +++W PC+ +
Sbjct: 138 TFAEKLVTQIIKNLQVKISSIHIRYEDDITNRDKPLSFGISLQNLSMQTTDQYWVPCLHD 197
Query: 241 EADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILDQLKNEILTSGNIPPNYQYIFQPIS 300
E +K++ KLIRLD+L AYWNV M Y + LD LKN I+ +P Y ++F+PIS
Sbjct: 198 ETEKLVRKLIRLDNLFAYWNVKSQMFYLSDYDNSLDDLKNGIVNENIVPEGYDFVFRPIS 257
Query: 301 ASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKPQYLSMIDLLESVDYMVRNAPYRKY 360
A+AKL MN ++ + PK++ IE+ NIAIE KPQY S+++LLESVD M +N PYRK+
Sbjct: 258 ANAKLVMNRRSDFDFSAPKINLEIELHNIAIEFNKPQYFSIMELLESVDMMAQNLPYRKF 317
Query: 361 KPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIKKHRQLLKSYKIAYKNKLTQSK 420
KP +PLH + R WW YAI VLEV++ MWSW +I+KHRQ +K YK YK KLT K
Sbjct: 318 KPDVPLHHHAREWWAYAIHGVLEVNVCPRLWMWSWKHIRKHRQKVKQYKELYKKKLTSKK 377
Query: 421 VSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKSADTGEKRGGWFSGLWGK 480
E+ +++LEKTLDVFNI +ARQ A+VEV ++G K+ K+ E GWFS LW
Sbjct: 378 PPGELLVSLEELEKTLDVFNITIARQTAEVEVKKAGYKIYKEGVKDPEDNKGWFSWLWSW 437
Query: 481 KESKKKDEE-SLIPETIDDLMTPEEKDKLFTAIGYSESTHNLTLPKQYVAHIMTLKLVST 539
E +++ + PET+++++TPEEK L+ AIGYSE+ + TL K + A + L S
Sbjct: 438 SEQNTNEQQPDVQPETLEEMLTPEEKALLYEAIGYSETAVDPTLLKTFEALKFFVHLKSM 497
Query: 540 SVTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVEAKLEHWYITGLRQQDIVPSLVAS 599
S+ +REN PE++ I I T + QRPGAQA+K E K++ ++ITGL P L++S
Sbjct: 498 SIVLRENHQKPELVDIVIEEFSTLIVQRPGAQAIKFETKIDSFHITGLPDNSEKPRLLSS 557
Query: 600 IGDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIYDAKTVNAVVEFFQSNKGLDLEQI 659
+ D SL +I FE NP D Q I++++P+E+IYDA+TVN++VEFF+ K + L Q+
Sbjct: 558 L-DDAMSLFQITFEINPLDETVSQRCIIEAEPLEIIYDARTVNSIVEFFRPPKEVHLAQL 616
Query: 660 TSATLMKLEEIKERTATGLTHIIETRKVLDLRINLKPSYLVVPQTGFHHEKSDLLILDFG 719
T+ATL KLEE + +TATGL +IIET+KVLDL+INLK SY++VPQ G S+LL+LD G
Sbjct: 617 TAATLTKLEEFRSKTATGLLYIIETQKVLDLKINLKASYIIVPQDGIFSPTSNLLLLDLG 676
Query: 720 TFQLNSKDQGL---QKTTNSSLEEIMDKAYDKFDVEIKNVQLLFARAEETWKKCRFQHPS 776
++ SK + K ++L+EIMD+AYD FD+++ +VQLL++R + W++ R S
Sbjct: 677 HLKVTSKSRSELPDVKQGEANLKEIMDRAYDSFDIQLTSVQLLYSRVGDNWREARKLSVS 736
Query: 777 TMHILQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVRISDQKMKDVLYLMNSIPLPQ 836
T HIL PM ++EL+KAMV D+RM +FK+ G LPL+ +RISD+K++ ++ L+ SIP P+
Sbjct: 737 TQHILVPMHFNLELSKAMVFMDVRMPKFKIYGKLPLISLRISDKKLQGIMELIESIPKPE 796
Query: 837 KSSAQSPERQVSS-IPIISGGTKGLLGTSLLLDTV----------ESESDDEYFDAEDGE 885
P +VS+ + T LGTS + + E +S++E+FDA
Sbjct: 797 ------PVTEVSAPVKSFQIQTSTSLGTSQISQKIIPLLELPSVSEDDSEEEFFDAPCSP 850
Query: 886 -------PQTCKSMKGSELKKAAEVPNEELINLLLKFEIKEVILEFTKQQKE-EDTILVF 937
P KS++ +L+K + + + ++FE+ +V++EF + E +++
Sbjct: 851 LEEPLQFPTGVKSIRTRKLQK--QDCSVNMTTFKIRFEVPKVLIEFYHLVGDCELSVVEI 908
Query: 938 NVTQLGTEATMRTFDLTVVSYLKKISLDYHEIEGSKRKPLHLISSSDKPGLDLLKVEYIK 997
V LG E +RT+DL ++LK+ L E +KP++L+++ D DLL +EY+K
Sbjct: 909 LVLGLGAEIEIRTYDLKANAFLKEFCLKCPEYLDENKKPVYLVTTLDNTMEDLLTLEYVK 968
Query: 998 ADKNGPSFQTAFGKTEQTVKVAFSSLNLLLQTQALVASINYLTTIIPSDDQSISVAKEVQ 1057
A+KN P ++ + Q +KV FSSL++ L T+AL+ +INYL I+P ++ K
Sbjct: 969 AEKNVPDLKSTYNNVLQLIKVNFSSLDIHLHTEALLNTINYLHNILPQSEE-----KSAP 1023
Query: 1058 ISTEKQQKNSTLPKAIVSSRDSDIIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSSLS 1117
+ST + + +K ++ IK GLDS +
Sbjct: 1024 VSTTETE-----------------------------------DKGDV--IKKLGLDSEMI 1046
Query: 1118 LQSRKQSLFARLENIIVTDVDPKTVHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMSKV 1177
++ + + A+L NIIV D D ++KKAV I G EVF F + Y DAT G YTDM+ V
Sbjct: 1047 MRPSETEINAKLRNIIVLDSDITAIYKKAVYITGKEVFSFKMVSYMDATAGSAYTDMNVV 1106
Query: 1178 DGVLSLNVGCIQIVYLHKFLMSLLNFLNNFQTAKESLSAATAQAAERAATSVKDLAQRSF 1237
D ++L VGCI++V++ KFL S+L F++NFQ AK++L+ AT QAA AAT VK+LAQRS
Sbjct: 1107 DIQVNLIVGCIEVVFVTKFLYSILAFIDNFQAAKQALAEATVQAAGMAATGVKELAQRSS 1166
Query: 1238 RVSINIDLKAPVIVIPQSSISTNAVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQLT 1297
R++++I++KAPV+VIPQS +S N V D GLI + N F ++++ PPVID + ++L+
Sbjct: 1167 RMALDINIKAPVVVIPQSPVSENVFVADFGLITMTNTFHMITESQSSPPPVIDLITIKLS 1226
Query: 1298 KLTLYRTVIQPGIYHPDIQLLHPINLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLNQ 1357
++ LYR+ Y + LL P+NLE +V RNL WY +VP + L M L+Q
Sbjct: 1227 EMRLYRSRFINDAYQEVLDLLLPLNLEVVVERNLCWEWYQEVPCFNVNAQLKPMEFILSQ 1286
Query: 1358 EDLNLLFRILTENL 1371
ED+ +F+ L N+
Sbjct: 1287 EDITTIFKTLHGNI 1300
Score = 54.7 bits (130), Expect = 2e-06
Identities = 82/394 (20%), Positives = 175/394 (44%), Gaps = 57/394 (14%)
Query: 1560 FSEPSSSEKESELKP------LVGESRSIAVKAVSSNISQKD-----VFD-LKITAELNA 1607
+SE +++E++ +++P L E +++ +A+ + + D F+ LK L +
Sbjct: 437 WSEQNTNEQQPDVQPETLEEMLTPEEKALLYEAIGYSETAVDPTLLKTFEALKFFVHLKS 496
Query: 1608 FNVFVCD--QKCNIADIKIHGMDASISVKPKQTDVF--ARLKDIIVMNVDLQSIHKKAVS 1663
++ + + QK + DI I I +P + ++ + + S + +S
Sbjct: 497 MSIVLRENHQKPELVDIVIEEFSTLIVQRPGAQAIKFETKIDSFHITGLPDNSEKPRLLS 556
Query: 1664 ILGDEVFRFQLTLYPDATEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQ 1723
L D + FQ+T + + V + + ++I+Y + S++ F F+
Sbjct: 557 SLDDAMSLFQITFEINPLD-------ETVSQRCIIEAEPLEIIYDARTVNSIVEF---FR 606
Query: 1724 TAKEA----LSTATVQAAE----RAASSMKDLAQKSFRLLMDINLKAPVIIIPQSSV--- 1772
KE L+ AT+ E + A+ + + + L + INLKA II+PQ +
Sbjct: 607 PPKEVHLAQLTAATLTKLEEFRSKTATGLLYIIETQKVLDLKINLKASYIIVPQDGIFSP 666
Query: 1773 SPNAVIADLGLIRVENK----FSLVPMEHYSLPPVIDK----MNIELTQLKLSRTIL--- 1821
+ N ++ DLG ++V +K V +L ++D+ +I+LT ++L + +
Sbjct: 667 TSNLLLLDLGHLKVTSKSRSELPDVKQGEANLKEIMDRAYDSFDIQLTSVQLLYSRVGDN 726
Query: 1822 ---QASLPQNDIEILKPVNMLLSIQRNLAAAWYVQIPGMEIKGKLKPMQVALSEDDLTVL 1878
L + IL P++ L + + + V++P +I GKL + + +S+ L +
Sbjct: 727 WREARKLSVSTQHILVPMHFNLELSKAM-VFMDVRMPKFKIYGKLPLISLRISDKKLQGI 785
Query: 1879 MKILLENLGEASSQPSPTQSVQETVRVRKVDVSS 1912
M+++ E+ +P P V V+ ++ S+
Sbjct: 786 MELI-----ESIPKPEPVTEVSAPVKSFQIQTST 814
Score = 33.5 bits (75), Expect = 4.1
Identities = 61/330 (18%), Positives = 128/330 (38%), Gaps = 36/330 (10%)
Query: 538 STSVTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVEAKLEHWYITGLRQQDIVPSLV 597
S V+ E ++ +++K +GL +++ RP ++ AKL + + I V
Sbjct: 1021 SAPVSTTETEDKGDVIKK--LGLDSEMIMRPSET--EINAKLRNIIVLDSDITAIYKKAV 1076
Query: 598 ASIGDTTSSLLKIKFETNPEDSPADQTLIVQSQP------VEVIYDAKTVNAVVEF---F 648
G S + + S +V Q +EV++ K + +++ F F
Sbjct: 1077 YITGKEVFSFKMVSYMDATAGSAYTDMNVVDIQVNLIVGCIEVVFVTKFLYSILAFIDNF 1136
Query: 649 QSNKGLDLEQITSATLMKLEEIKERTATGLTHIIETRKVLDLRINLKPSYLVVPQTGFHH 708
Q+ K E A M ATG+ + + + L IN+K +V+PQ+
Sbjct: 1137 QAAKQALAEATVQAAGM--------AATGVKELAQRSSRMALDINIKAPVVVIPQSPV-- 1186
Query: 709 EKSDLLILDFGTFQLNSKDQGLQKTTNSSLEEIMDKAYDKFDVEIKNVQLLFARAEETWK 768
++ + DFG + + + ++ +S I D +++ ++L +R
Sbjct: 1187 -SENVFVADFGLITMTNTFHMITESQSSPPPVI-----DLITIKLSEMRLYRSRF----- 1235
Query: 769 KCRFQHPSTMHILQPMDIHVELAKAMV-EKDIRMARFKVSGGLPLMHVRISDQKMKDVLY 827
+ + +L P+++ V + + + E + F V+ L M +S + + +
Sbjct: 1236 -INDAYQEVLDLLLPLNLEVVVERNLCWEWYQEVPCFNVNAQLKPMEFILSQEDITTIFK 1294
Query: 828 LMNSIPLPQKSSAQSPERQVSSIPIISGGT 857
++ +K + SP SG T
Sbjct: 1295 TLHGNIWYEKDGSASPAVTKDQYSATSGVT 1324
>gi|54607141 vacuolar protein sorting 13D isoform 2 [Homo sapiens]
Length = 4363
Score = 218 bits (555), Expect = 9e-56
Identities = 320/1522 (21%), Positives = 604/1522 (39%), Gaps = 311/1522 (20%)
Query: 2 VLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAGQ 61
+LE +VA +LN +LG YV NLN QL + + G V L+NL +K++AL EL++PF+VKAG
Sbjct: 1 MLEGLVAWVLNTYLGKYVNNLNTDQLSVALLKGAVELENLPLKKDALKELELPFEVKAGF 60
Query: 62 IDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEEA 121
I K+TL+IP+ + + V ++ L+L+ GA K +EK K E R +
Sbjct: 61 IGKVTLQIPFYRPHVDPWVISISSLHLI---GAPEKIQDFNDEKE----KLLERERKKAL 113
Query: 122 LQKAAEKGTHSGEFIYGLENFVYKDIKPGRKRKKHKKHFKKPFKGLDRSKDKPKEAKKDT 181
LQ EK K R++K + +
Sbjct: 114 LQALEEKW------------------KNDRQQKGESYWY--------------------S 135
Query: 182 FVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLGELSLLTANEHWTPCILNE 241
+ T++++N+++KI D+H+++ED VT+P P +FG+ + +S+ A +NE
Sbjct: 136 VTASVVTRIVENIELKIQDVHLRFEDGVTNPSHPFAFGICIKNVSMQNA--------VNE 187
Query: 242 ADKIIYKLIRLD--SLSAYWNVNCSMSYQRSREQILDQLKNEILTSGNIPPNYQYIFQPI 299
+ + + +LD S YW+V+C++ + ++ + + + + ++ Y+ +P+
Sbjct: 188 PVQKLMRKKQLDVAEFSIYWDVDCTLLGDLPQMELQEAMARSMESR-----SHHYVLEPV 242
Query: 300 SASAKLYMNPYAESELKT---PKLDCNIEIQNIAIELTKPQYLSMIDLLESVDYMVRNAP 356
ASA L N ++ L++ P++DC+I+++ I ++L++ QY +++ L+ ++ R
Sbjct: 243 FASALLKRN-CSKKPLRSRHSPRIDCDIQLETIPLKLSQLQYRQIMEFLKELERKERQVK 301
Query: 357 YRKYKPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIKKHRQLLKSYKIAYKNKL 416
+R++KP + + N R WW +A+++ L IR + +W + + SY Y NKL
Sbjct: 302 FRRWKPKVAISKNCREWWYFALNANL-YEIREQRKRCTWDFMLHRARDAVSYTDKYFNKL 360
Query: 417 TQSKVSEEIQKEIQDLEKTLDVFNIILAR---------QQAQVEVIRSGQKLRKKSADTG 467
+S + ++E+ +E+ + + R Q+ E +R Q +
Sbjct: 361 KGGLLSTDDKEEMCRIEEEQSFEELKILRELVHDRFHKQEELAESLREPQFDSPGACPGA 420
Query: 468 EKRGG----------WFSGLWGKKESKK------------KDEESLIPETI--------- 496
+ GG WF G WG ++ + +E IPE I
Sbjct: 421 PEPGGGSGMLQYLQSWFPG-WGGWYGQQTPEGNVVEGLSAEQQEQWIPEEILGTEEFFDP 479
Query: 497 ----DDLMTPEEKDKLFTAIGYSESTHNLTL-------PKQYVAHIMTL-----KLVSTS 540
+ T ++D +F + +TL P+ + M L KL++ S
Sbjct: 480 TADASCMNTYTKRDHVFAKLNLQLQRGTVTLLHKEQGTPQMNESAFMQLEFSDVKLLAES 539
Query: 541 VTIRENKNIPEILKIQIIGL--------GTQ----VSQRPGAQALKVEAKLEHWYITGLR 588
+ R + +L +++ GL GT V P + +V GL+
Sbjct: 540 LPRRNS----SLLSVRLGGLFLRDLATEGTMFPLLVFPNPQKEVGRVSQSF------GLQ 589
Query: 589 QQDIVPSLVASIGDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIYDAKTVNAVVEFF 648
S D + ++ +E NP S ++ L V ++P+ +IY+ + + V +FF
Sbjct: 590 TTSADRSDHYPAADPDGPVFEMLYERNPAHSHFERRLNVSTRPLNIIYNPQAIKKVADFF 649
Query: 649 QSNK------GLDLE---QITSATLMKLEEIKERTATGLTH---------IIETRKVLDL 690
K G E ++ A + ++K +T + IE K +
Sbjct: 650 YKGKVHTSGFGYQSELELRVAEAARRQYNKLKMQTKAEIRQTLDRLLVGDFIEESKRWTV 709
Query: 691 RINLKPSYLVVPQTGFHHEKSDLLILDFGTFQL-NSKDQGLQKTTNSSLEE--------- 740
R+++ ++ P F + L+++D G L N++D +K+ + S E
Sbjct: 710 RLDISAPQVIFPD-DFKFKNPVLVVVDLGRMLLTNTQDNSRRKSRDGSASEETQFSDDEY 768
Query: 741 ----------------------------------------IMDKAYDKFDVEIKNVQLLF 760
+ K Y+++ + ++Q++
Sbjct: 769 KTPLATPPNTPPPESSSSNGEKTPPFSGVEFSEEQLQAHLMSTKMYERYSLSFMDLQIMV 828
Query: 761 ARAEETWKKCRFQHPSTMHILQPMDIHVELAKAMV-EKDIRMARFKVSGGLPLMHVRISD 819
R ++ WK + H+++ ++H++L + ++ D + +SG LP + + I++
Sbjct: 829 GRVKDNWKHVQDIDVGPTHVVEKFNVHLQLERRLIYTSDPKYPGAVLSGNLPDLKIHINE 888
Query: 820 QKMKDVLYLMNSIPLPQKSSAQSPERQVSSIPIISGGTKGLLGTSLLLDTVESESDDEYF 879
K + L N L ++ + Q+ +G L S++ T +++
Sbjct: 889 DK---ISALKNCFALLTTPEMKTSDTQIKEKIFPQEEQRGSLQDSVMNLTQSIVLLEQHT 945
Query: 880 DAEDGEPQTCKSMKGSELKKAAEVPNEELINLLLKFEIKEVILEFTKQQKEEDTILVFNV 939
E Q + + N I++L F F K+ + + L V
Sbjct: 946 REVLVESQLLLAEFKVNCMQLGVESNGRYISVLKVFGTN---AHFVKRPYDAEVSL--TV 1000
Query: 940 TQLGTEATMRT----FDLTVVSYLKKISLDY--------------------HEIEGSKRK 975
L TM+T FDL + S+ K +S D H +G+
Sbjct: 1001 HGLLLVDTMQTYGADFDLLMASH-KNLSFDIPTGSLRDSRAQSPVSGPNVAHLTDGATLN 1059
Query: 976 PLHLISSS-----DKPGLDLLKVEYIKADKNGPSFQTAFGKTEQTVKVAFSSLNLLLQTQ 1030
S S K L+K+EY PS T Q + + ++L+++L +
Sbjct: 1060 DRSATSVSLDKILTKEQESLIKLEYQFVSSECPSMN--LDSTLQVISLQVNNLDIILNPE 1117
Query: 1031 ALVASINYLTTIIPSDDQSISVAKEVQISTEKQQKNSTLPKAIVSSRDSDIIDFRLFAKL 1090
+V I +L P + +S + ++ T + + + RL L
Sbjct: 1118 TIVELIGFLQKSFPKEKDDLSPQPLMTDFERSFREQGTYQSTYEQNTEVAVEIHRLNLLL 1177
Query: 1091 NAFCVIVCNEK--NNIAEIKIQGLDSSLSLQSRKQSLFARLENIIVTDVDPKTVHKKAVS 1148
+ EK IA I G ++S+ S + L + + D+ V + V
Sbjct: 1178 LRTVGMANREKYGRKIATASIGGTKVNVSMGS-TFDMNGSLGCLQLMDLTQDNVKNQYVV 1236
Query: 1149 IMGNEVFRFNL--DL---------YPDA--TEGDLYT--DMSKVDGVLSLNVGCIQIVYL 1193
+GN V N+ D+ DA TE +T + SK + L+L + + +
Sbjct: 1237 SIGNSVGYENIISDIGYFESVFVRMEDAALTEALSFTFVERSKQECFLNLKMASLHYNHS 1296
Query: 1194 HKFLMSLL--------NFLNNFQTAKESLSAATAQAAERAATSVK--------------- 1230
KFL L NF ++A ++ A + V
Sbjct: 1297 AKFLKELTLSMDELEENFRGMLKSAATKVTTVLATKTAEYSEMVSLFETPRKTREPFILE 1356
Query: 1231 -------DLAQR---SFRVSINIDLKAPVIVIPQSSISTNAVVVDLGLIRVHNQFSLVSD 1280
DLA + ++ +NI++++PV+ IP+ S +V LG I + N F D
Sbjct: 1357 ENEIYGFDLASSHLDTVKLILNINIESPVVSIPRKPGSPELLVGHLGQIFIQN-FVAGDD 1415
Query: 1281 EDYLNPPVIDRMDVQLTKLTLY 1302
E DR+ V++ + LY
Sbjct: 1416 ESR-----SDRLQVEIKDIKLY 1432
Score = 144 bits (362), Expect = 2e-33
Identities = 139/573 (24%), Positives = 260/573 (45%), Gaps = 61/573 (10%)
Query: 3184 LSGIQIEFKQSSHQRSLRARLYWLQVDNQLPGAMFPVVFHPVAPPKSIALDSEPKPFIDV 3243
L+GI + + Q + L + +QVDNQL G P + + V P + E P + V
Sbjct: 3829 LTGINVHYTQLATSHMLELSIQDVQVDNQLIGTTQPFMLY-VTPLSNENEVIETGPAVQV 3887
Query: 3244 SVITRFNEYSKVLQFKYFMVLIQEMALKIDQGFLGAIIALFTPTTDPEAERRRTKLIQQD 3303
+ + ++ + +K+ M+ Q ++I++ L +++ F E+E +++
Sbjct: 3888 NAVKFPSKSALTNIYKHLMITAQRFTVQIEEKLLLKLLSFFG-YDQAESE------VEKY 3940
Query: 3304 IDALNAELMETSMTDMSILSFFEHFHISPVKLHLSLSLGSGGEESDKEKQEMFAVHSVNL 3363
+ L+ + E T I +FE+ IS ++ LS+ S+K ++ A+ S
Sbjct: 3941 DENLHEKTAEQGGTP--IRYYFENLKISIPQIKLSVFT------SNKLPLDLKALKS--- 3989
Query: 3364 LLKSIGATLTDVDDLIFKLAYYEIRYQFYKRDQLIWSVVRHYSEQFLKQMYVLVLGLDVL 3423
++G L +D + L + + + ++ +I +++H+ E+ L Q ++ +D L
Sbjct: 3990 ---TLGFPLIRFEDAVINLDPFTRVHPYETKEFIINDILKHFQEELLSQAARILGSVDFL 4046
Query: 3424 GNPFGLIRGLSEGVEALFYEPFQGAVQGPEEFAEGLVIGVRSLFGHTVGGAAGVVSRITG 3483
GNP GL+ +SEGV L G V G L + G + ++ G
Sbjct: 4047 GNPMGLLNDVSEGVTGLIK---YGNVGG--------------LIRNVTHGVSNSAAKFAG 4089
Query: 3484 SVGKGLAAITMDKEYQQKRREELSRQPRDFGDSLARGGKGFLRGVVGGVTGIITKPVEGA 3543
++ GL TMD +Q + RE + G+ L G G G++GG+T +IT VEG
Sbjct: 4090 TLSDGLGK-TMDNRHQSE-REYIRYHAATSGEHLVAGIHGLAHGIIGGLTSVITSTVEGV 4147
Query: 3544 KKE-GAAGFFKGIGKGLVGAVARPTGGIVDMASSTFQGIQRAAEST---EEVSSLRPPR- 3598
K E G +GF G+GKGLVG V +P G +D AS T Q ++ A + + +R PR
Sbjct: 4148 KTEGGVSGFISGLGKGLVGTVTKPVAGALDFASETAQAVRDTATLSGPRTQAQRVRKPRC 4207
Query: 3599 LIHEDGIIRPYDRQESEGSDLLENHIKKLEGETYRYHCAIPGSKKTILMVTNRRVLCIKE 3658
G++ Y ++EG + L ++ E + A+ ++++++ V +K
Sbjct: 4208 CTGPQGLLPRYSESQAEGQEQLFKLTDNIQDE---FFIAVENIDSYCVLISSKAVYFLKS 4264
Query: 3659 VEILGLMCVDWQCPFEDFVFPPSVSENVLKISVKEQGLFHKKDSANQGC--------VRK 3710
+ + + + ++D ++ VS++ K+ V+ + K S + G
Sbjct: 4265 GDYVDREAIFLEVKYDD-LYHCLVSKDHGKVYVQ---VTKKAVSTSSGVSIPGPSHQKPM 4320
Query: 3711 VYLKDTATAERACNAIEDAQSTRQQQKLMKQSS 3743
V++K A + I A+S +Q+LM + S
Sbjct: 4321 VHVKSEVLAVKLSQEINYAKSLYYEQQLMLRLS 4353
Score = 84.3 bits (207), Expect = 2e-15
Identities = 65/289 (22%), Positives = 140/289 (48%), Gaps = 17/289 (5%)
Query: 990 LLKVEYIKADKNGPSFQTAFGKTEQTVKVAFSSLNLLLQTQALVASINYLTTIIPSDDQS 1049
L+ + DK P F +++ + +++ V F+ L++L+ Q V +++ +D+ +
Sbjct: 1784 LVHINIFLVDKKHPEFSSSYNRVNRSIDVDFNCLDVLITLQTWVVILDFFGIGSTADNHA 1843
Query: 1050 ISVAKEVQISTEKQQKNSTLPKAIVSSRDSDIIDFRLFAKLNAFCVIVCNEKNNIAEIKI 1109
+ + E + K + P A + S D ++ +L K+++ +++ + +A+ +
Sbjct: 1844 MRLPPEGILHNVKLE-----PHASMESGLQDPVNTKLDLKVHSLSLVLNKTTSELAKANV 1898
Query: 1110 QGLDSSLSLQSRKQSLFARLENIIVTDVDPK-TVHKKAVSIMGNEVFRFNLDLY--PDAT 1166
L + L + +L + ++ ++D+ +++ + G E F Y PD
Sbjct: 1899 SKLVAHLEMIEGDLALQGSIGSLSLSDLTCHGEFYRERFTTSGEEALIFQTFKYGRPDPL 1958
Query: 1167 EGDLYTDMSKVDGVLSLNVGCIQIVYLHKFLMSLLNFLNNFQTAKESLSAATAQAAERAA 1226
+ D +SL + +Q V+ +F ++ F+ +F ++ L Q A
Sbjct: 1959 L------RREHDIRVSLRMASVQYVHTQRFQAEVVAFIQHFTQLQDVLGR---QRAAIEG 2009
Query: 1227 TSVKDLAQRSFRVSINIDLKAPVIVIPQSSISTNAVVVDLGLIRVHNQF 1275
+V+D AQR RV ++I+ APV++IP+SS S N +V +LG ++V N+F
Sbjct: 2010 QTVRDQAQRCSRVLLDIEAGAPVLLIPESSRSNNLIVANLGKLKVKNKF 2058
Score = 82.8 bits (203), Expect = 6e-15
Identities = 66/305 (21%), Positives = 147/305 (48%), Gaps = 20/305 (6%)
Query: 1490 EPLHIINSSNVTDEPLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLHLEALLS 1549
EP ++ S D+ L+ + + D PEF + ++ + + V F LD+++ L+ +
Sbjct: 1770 EPKILVGKSKF-DDSLVHINIFLVDKKHPEFSSSYNRVNRSIDVDFNCLDVLITLQTWVV 1828
Query: 1550 FMDFLSSAAPFSEPSSSEKESELKPLVGESRSIAVKAVSSNISQ-KDVFDLKITAELNAF 1608
+DF F S+++ + P G ++ ++ +S S +D + K+ ++++
Sbjct: 1829 ILDF------FGIGSTADNHAMRLPPEGILHNVKLEPHASMESGLQDPVNTKLDLKVHSL 1882
Query: 1609 NVFVCDQKCNIADIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQS-IHKKAVSILGD 1667
++ + +A + + A + + + + + + ++ +++ + G+
Sbjct: 1883 SLVLNKTTSELAKANVSKLVAHLEMIEGDLALQGSIGSLSLSDLTCHGEFYRERFTTSGE 1942
Query: 1668 EVFRFQLTLY--PDATEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQTA 1725
E FQ Y PD + D ++S ++ +Q V+ +F ++ F+ +F
Sbjct: 1943 EALIFQTFKYGRPDPLLRREH------DIRVSLRMASVQYVHTQRFQAEVVAFIQHFTQL 1996
Query: 1726 KEALSTATVQAAERAASSMKDLAQKSFRLLMDINLKAPVIIIPQSSVSPNAVIADLGLIR 1785
++ L Q A +++D AQ+ R+L+DI APV++IP+SS S N ++A+LG ++
Sbjct: 1997 QDVLGR---QRAAIEGQTVRDQAQRCSRVLLDIEAGAPVLLIPESSRSNNLIVANLGKLK 2053
Query: 1786 VENKF 1790
V+NKF
Sbjct: 2054 VKNKF 2058
Score = 53.9 bits (128), Expect = 3e-06
Identities = 96/441 (21%), Positives = 173/441 (39%), Gaps = 70/441 (15%)
Query: 2662 YIIHLYPSLTLRNLLPYSLRYLLEGTAETHELAEGSTADVLHSRISGEIMEL-------- 2713
+ I+L P++ + NLLP L + ++G L G A LH+ + + +EL
Sbjct: 3151 HTIYLLPTVVICNLLPCELDFYVKGMPINGTLKPGKEA-ALHTADTSQNIELGVSLENFP 3209
Query: 2714 ----VLVKYQGKNWNGHFRIRDTLPEFFPVCFSSDSTEVTTVDLSVHVRRIGSRMVLSVF 2769
+L+ +N+ R+ D + + + + R GS + +
Sbjct: 3210 LCKELLIPPGTQNYMVRMRLYDV------------NRRQLNLTIRIVCRAEGSLKIF-IS 3256
Query: 2770 SPYWLINKTTRVLQYRSEDIHVKHPADFRD--------IILFSFKKKNIFTKNKVQLKIS 2821
+PYWLINKT L +R ++ F + +LF + K N ++I
Sbjct: 3257 APYWLINKTGLPLIFRQDNAKTDAAGQFEEHELARSLSPLLFCYADKE--QPNLCTMRIG 3314
Query: 2822 TS-------AWSSSFSLDTVGSYGCVKCPAN----NMEYLVGVSIK--MSSFNLSRIVTL 2868
W FSLD +K + Y +G+ +K + + +V
Sbjct: 3315 RGIHPEGMPGWCQGFSLDGGSGVRALKVIQQGNRPGLIYNIGIDVKKGRGRYIDTCMVIF 3374
Query: 2869 TPFCTIANKSSLELEVGEIA-SDGSMPTNKWNYIAS---SECLPFWPES-LSGKLCVR-- 2921
P + NKSS +L + + G N YI++ S + WP + LCVR
Sbjct: 3375 APRYLLDNKSSHKLAFAQREFARGQGTANPEGYISTLPGSSVVFHWPRNDYDQLLCVRLM 3434
Query: 2922 -VVGCEGSSKPFFYNRQDNGTLLSLEDLNGG---ILVDVNTAEHSTVITFSDYHEGSAPA 2977
V C S F ++N +++ D G + V++ + I+FSD + P
Sbjct: 3435 DVPNCIWSGG--FEVNKNNSFHINMRDTLGKCFFLRVEITLRGATYRISFSDTDQLPPPF 3492
Query: 2978 LIMNHTPWDILTYKQSGSPEEMV---LLPRQARLFAWADPTGTRKLTWTYAANVGEHDLL 3034
I N + ++ + Q G E + + P + +AW +PT +T T G ++
Sbjct: 3493 RIDNFSKVPVV-FTQHGVAEPRLRTEVKPMTSLDYAWDEPTLPPFITLT-VKGAGSSEI- 3549
Query: 3035 KDGCGQFPYDANIQIHWVSFL 3055
C + N Q+++ +F+
Sbjct: 3550 --NCNMNDFQDNRQLYYENFI 3568
Score = 52.0 bits (123), Expect = 1e-05
Identities = 122/611 (19%), Positives = 236/611 (38%), Gaps = 138/611 (22%)
Query: 1317 LLHPINLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLNQEDLNLL---FRILT--ENL 1371
++ N+ + R L + K P + G+L + + +N++ ++ L F +LT E
Sbjct: 848 VVEKFNVHLQLERRLIYTSDPKYPGAVLSGNLPDLKIHINEDKISALKNCFALLTTPEMK 907
Query: 1372 CEGTEDLDKVKPRVQETGEIKEPLEISISQDVHDSKNTLTTGVEEIRSVDIINMLLNFEI 1431
T+ +K+ P+ ++ G S+ V + ++ + R V + + LL E
Sbjct: 908 TSDTQIKEKIFPQEEQRG--------SLQDSVMNLTQSIVLLEQHTREVLVESQLLLAEF 959
Query: 1432 KEVVVTLMKKSEKKGRPLHELNVLQLGMEAKVKTYD----MTAKAYLKKISMQCF--DFT 1485
K V + E GR + L V + YD +T L +MQ + DF
Sbjct: 960 K--VNCMQLGVESNGRYISVLKVFGTNAHFVKRPYDAEVSLTVHGLLLVDTMQTYGADFD 1017
Query: 1486 -------------------DSKGE-PLHIINSSNVTD----------------------E 1503
DS+ + P+ N +++TD E
Sbjct: 1018 LLMASHKNLSFDIPTGSLRDSRAQSPVSGPNVAHLTDGATLNDRSATSVSLDKILTKEQE 1077
Query: 1504 PLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLHLEALLSFMDFLSSAAPFSEP 1563
L+K+ S+ P DST Q + + +LD++L+ E ++ + FL + P +
Sbjct: 1078 SLIKLEYQFVSSECPSMNL--DSTLQVISLQVNNLDIILNPETIVELIGFLQKSFPKEKD 1135
Query: 1564 SSSEKESELKPLVGE-SRSIAVKAVSSNISQKDVFDLKITAELNAFNVFVC--------- 1613
S + PL+ + RS + + +++ ++ E++ N+ +
Sbjct: 1136 DLSPQ-----PLMTDFERSFREQGTYQSTYEQNT---EVAVEIHRLNLLLLRTVGMANRE 1187
Query: 1614 DQKCNIADIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQSIHKKAVSILGDEV---- 1669
IA I G ++S+ D+ L + +M++ ++ + V +G+ V
Sbjct: 1188 KYGRKIATASIGGTKVNVSMG-STFDMNGSLGCLQLMDLTQDNVKNQYVVSIGNSVGYEN 1246
Query: 1670 -------FRFQLTLYPDATEGEA----YADMSKVDGKLSFKVGCIQIVYVHKFF----MS 1714
F DA EA + + SK + L+ K+ + + KF +S
Sbjct: 1247 IISDIGYFESVFVRMEDAALTEALSFTFVERSKQECFLNLKMASLHYNHSAKFLKELTLS 1306
Query: 1715 LLNFLNNFQTAKEALST--ATVQAAERAASSMK------------------------DLA 1748
+ NF+ ++ +T TV A + A S DLA
Sbjct: 1307 MDELEENFRGMLKSAATKVTTVLATKTAEYSEMVSLFETPRKTREPFILEENEIYGFDLA 1366
Query: 1749 QK---SFRLLMDINLKAPVIIIPQSSVSPNAVIADLGLIRVENKFSLVPMEHYSLPPVID 1805
+ +L+++IN+++PV+ IP+ SP ++ LG I ++N F E S D
Sbjct: 1367 SSHLDTVKLILNINIESPVVSIPRKPGSPELLVGHLGQIFIQN-FVAGDDESRS-----D 1420
Query: 1806 KMNIELTQLKL 1816
++ +E+ +KL
Sbjct: 1421 RLQVEIKDIKL 1431
Score = 39.7 bits (91), Expect = 0.057
Identities = 86/375 (22%), Positives = 148/375 (39%), Gaps = 50/375 (13%)
Query: 1317 LLHPINLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLNQEDLNLLFRILTENLCEGTE 1376
L P L+ V RNL H VP + I G+L S++ SL+ L+ +L NL E E
Sbjct: 2201 LTEPCRLKLQVERNLDKEISHTVPDISIHGNLSSVHCSLDLYKYKLIRGLLENNLGEPIE 2260
Query: 1377 DLDKVKPRVQETGEIKEP-LEISISQDVHDSKNTLTTGVEEIRSVDIINMLLNF---EIK 1432
+ ++P ++++P + +S +V+ L +D++N+ L + K
Sbjct: 2261 EF--MRPY-----DLQDPRIHTVLSGEVYTCMCFL---------IDMVNVSLELKDPKRK 2304
Query: 1433 EVVVTLMKKSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFD--FTDSKGE 1490
E +L + KK + L+E + T L SM FD + K
Sbjct: 2305 EGAGSLARFDFKKCKLLYE------------SFSNQTKSINLVSHSMMAFDTRYAGQKTS 2352
Query: 1491 PLHIINSSNVTDEPLLKMLLTKADSD-GPEFKTIHDSTKQRLKVSFASLDLVLHLEALLS 1549
P + N + +P T+ F++ DS+ V +L + L + LL
Sbjct: 2353 P-GMTNVFSCIFQPAKNSSTTQGSIQIELHFRSTKDSS--CFTVVLNNLRVFLIFDWLLL 2409
Query: 1550 FMDFLSSAAPF--------SEPSSSEKESELKPLVGESRSIAVKAVSSNISQKDVFDLKI 1601
DFL + + S +S ES + P +S + K S +S + ++K+
Sbjct: 2410 VHDFLHTPSDIKKQNHVTPSRHRNSSSESAIVPKTVKS-GVVTKRSSLPVSNERHLEVKV 2468
Query: 1602 TAELNAFNVFVCDQKCNIADIKIHGMDASISVKPKQTD--VFARLKDIIVMNVDLQSIHK 1659
F V + D C + I ++ KP+ D L I V + L + H
Sbjct: 2469 NVTGTEF-VVIEDVSCFDTNAIILKGTTVLTYKPRFVDRPFSGSLFGIEVFSCRLGNEHD 2527
Query: 1660 KAVSILGDEVFRFQL 1674
A+SI+ + +L
Sbjct: 2528 TALSIVDPVQIQMEL 2542
>gi|54607139 vacuolar protein sorting 13D isoform 1 [Homo sapiens]
Length = 4388
Score = 218 bits (555), Expect = 9e-56
Identities = 320/1522 (21%), Positives = 604/1522 (39%), Gaps = 311/1522 (20%)
Query: 2 VLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAGQ 61
+LE +VA +LN +LG YV NLN QL + + G V L+NL +K++AL EL++PF+VKAG
Sbjct: 1 MLEGLVAWVLNTYLGKYVNNLNTDQLSVALLKGAVELENLPLKKDALKELELPFEVKAGF 60
Query: 62 IDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEEA 121
I K+TL+IP+ + + V ++ L+L+ GA K +EK K E R +
Sbjct: 61 IGKVTLQIPFYRPHVDPWVISISSLHLI---GAPEKIQDFNDEKE----KLLERERKKAL 113
Query: 122 LQKAAEKGTHSGEFIYGLENFVYKDIKPGRKRKKHKKHFKKPFKGLDRSKDKPKEAKKDT 181
LQ EK K R++K + +
Sbjct: 114 LQALEEKW------------------KNDRQQKGESYWY--------------------S 135
Query: 182 FVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLGELSLLTANEHWTPCILNE 241
+ T++++N+++KI D+H+++ED VT+P P +FG+ + +S+ A +NE
Sbjct: 136 VTASVVTRIVENIELKIQDVHLRFEDGVTNPSHPFAFGICIKNVSMQNA--------VNE 187
Query: 242 ADKIIYKLIRLD--SLSAYWNVNCSMSYQRSREQILDQLKNEILTSGNIPPNYQYIFQPI 299
+ + + +LD S YW+V+C++ + ++ + + + + ++ Y+ +P+
Sbjct: 188 PVQKLMRKKQLDVAEFSIYWDVDCTLLGDLPQMELQEAMARSMESR-----SHHYVLEPV 242
Query: 300 SASAKLYMNPYAESELKT---PKLDCNIEIQNIAIELTKPQYLSMIDLLESVDYMVRNAP 356
ASA L N ++ L++ P++DC+I+++ I ++L++ QY +++ L+ ++ R
Sbjct: 243 FASALLKRN-CSKKPLRSRHSPRIDCDIQLETIPLKLSQLQYRQIMEFLKELERKERQVK 301
Query: 357 YRKYKPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIKKHRQLLKSYKIAYKNKL 416
+R++KP + + N R WW +A+++ L IR + +W + + SY Y NKL
Sbjct: 302 FRRWKPKVAISKNCREWWYFALNANL-YEIREQRKRCTWDFMLHRARDAVSYTDKYFNKL 360
Query: 417 TQSKVSEEIQKEIQDLEKTLDVFNIILAR---------QQAQVEVIRSGQKLRKKSADTG 467
+S + ++E+ +E+ + + R Q+ E +R Q +
Sbjct: 361 KGGLLSTDDKEEMCRIEEEQSFEELKILRELVHDRFHKQEELAESLREPQFDSPGACPGA 420
Query: 468 EKRGG----------WFSGLWGKKESKK------------KDEESLIPETI--------- 496
+ GG WF G WG ++ + +E IPE I
Sbjct: 421 PEPGGGSGMLQYLQSWFPG-WGGWYGQQTPEGNVVEGLSAEQQEQWIPEEILGTEEFFDP 479
Query: 497 ----DDLMTPEEKDKLFTAIGYSESTHNLTL-------PKQYVAHIMTL-----KLVSTS 540
+ T ++D +F + +TL P+ + M L KL++ S
Sbjct: 480 TADASCMNTYTKRDHVFAKLNLQLQRGTVTLLHKEQGTPQMNESAFMQLEFSDVKLLAES 539
Query: 541 VTIRENKNIPEILKIQIIGL--------GTQ----VSQRPGAQALKVEAKLEHWYITGLR 588
+ R + +L +++ GL GT V P + +V GL+
Sbjct: 540 LPRRNS----SLLSVRLGGLFLRDLATEGTMFPLLVFPNPQKEVGRVSQSF------GLQ 589
Query: 589 QQDIVPSLVASIGDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIYDAKTVNAVVEFF 648
S D + ++ +E NP S ++ L V ++P+ +IY+ + + V +FF
Sbjct: 590 TTSADRSDHYPAADPDGPVFEMLYERNPAHSHFERRLNVSTRPLNIIYNPQAIKKVADFF 649
Query: 649 QSNK------GLDLE---QITSATLMKLEEIKERTATGLTH---------IIETRKVLDL 690
K G E ++ A + ++K +T + IE K +
Sbjct: 650 YKGKVHTSGFGYQSELELRVAEAARRQYNKLKMQTKAEIRQTLDRLLVGDFIEESKRWTV 709
Query: 691 RINLKPSYLVVPQTGFHHEKSDLLILDFGTFQL-NSKDQGLQKTTNSSLEE--------- 740
R+++ ++ P F + L+++D G L N++D +K+ + S E
Sbjct: 710 RLDISAPQVIFPD-DFKFKNPVLVVVDLGRMLLTNTQDNSRRKSRDGSASEETQFSDDEY 768
Query: 741 ----------------------------------------IMDKAYDKFDVEIKNVQLLF 760
+ K Y+++ + ++Q++
Sbjct: 769 KTPLATPPNTPPPESSSSNGEKTPPFSGVEFSEEQLQAHLMSTKMYERYSLSFMDLQIMV 828
Query: 761 ARAEETWKKCRFQHPSTMHILQPMDIHVELAKAMV-EKDIRMARFKVSGGLPLMHVRISD 819
R ++ WK + H+++ ++H++L + ++ D + +SG LP + + I++
Sbjct: 829 GRVKDNWKHVQDIDVGPTHVVEKFNVHLQLERRLIYTSDPKYPGAVLSGNLPDLKIHINE 888
Query: 820 QKMKDVLYLMNSIPLPQKSSAQSPERQVSSIPIISGGTKGLLGTSLLLDTVESESDDEYF 879
K + L N L ++ + Q+ +G L S++ T +++
Sbjct: 889 DK---ISALKNCFALLTTPEMKTSDTQIKEKIFPQEEQRGSLQDSVMNLTQSIVLLEQHT 945
Query: 880 DAEDGEPQTCKSMKGSELKKAAEVPNEELINLLLKFEIKEVILEFTKQQKEEDTILVFNV 939
E Q + + N I++L F F K+ + + L V
Sbjct: 946 REVLVESQLLLAEFKVNCMQLGVESNGRYISVLKVFGTN---AHFVKRPYDAEVSL--TV 1000
Query: 940 TQLGTEATMRT----FDLTVVSYLKKISLDY--------------------HEIEGSKRK 975
L TM+T FDL + S+ K +S D H +G+
Sbjct: 1001 HGLLLVDTMQTYGADFDLLMASH-KNLSFDIPTGSLRDSRAQSPVSGPNVAHLTDGATLN 1059
Query: 976 PLHLISSS-----DKPGLDLLKVEYIKADKNGPSFQTAFGKTEQTVKVAFSSLNLLLQTQ 1030
S S K L+K+EY PS T Q + + ++L+++L +
Sbjct: 1060 DRSATSVSLDKILTKEQESLIKLEYQFVSSECPSMN--LDSTLQVISLQVNNLDIILNPE 1117
Query: 1031 ALVASINYLTTIIPSDDQSISVAKEVQISTEKQQKNSTLPKAIVSSRDSDIIDFRLFAKL 1090
+V I +L P + +S + ++ T + + + RL L
Sbjct: 1118 TIVELIGFLQKSFPKEKDDLSPQPLMTDFERSFREQGTYQSTYEQNTEVAVEIHRLNLLL 1177
Query: 1091 NAFCVIVCNEK--NNIAEIKIQGLDSSLSLQSRKQSLFARLENIIVTDVDPKTVHKKAVS 1148
+ EK IA I G ++S+ S + L + + D+ V + V
Sbjct: 1178 LRTVGMANREKYGRKIATASIGGTKVNVSMGS-TFDMNGSLGCLQLMDLTQDNVKNQYVV 1236
Query: 1149 IMGNEVFRFNL--DL---------YPDA--TEGDLYT--DMSKVDGVLSLNVGCIQIVYL 1193
+GN V N+ D+ DA TE +T + SK + L+L + + +
Sbjct: 1237 SIGNSVGYENIISDIGYFESVFVRMEDAALTEALSFTFVERSKQECFLNLKMASLHYNHS 1296
Query: 1194 HKFLMSLL--------NFLNNFQTAKESLSAATAQAAERAATSVK--------------- 1230
KFL L NF ++A ++ A + V
Sbjct: 1297 AKFLKELTLSMDELEENFRGMLKSAATKVTTVLATKTAEYSEMVSLFETPRKTREPFILE 1356
Query: 1231 -------DLAQR---SFRVSINIDLKAPVIVIPQSSISTNAVVVDLGLIRVHNQFSLVSD 1280
DLA + ++ +NI++++PV+ IP+ S +V LG I + N F D
Sbjct: 1357 ENEIYGFDLASSHLDTVKLILNINIESPVVSIPRKPGSPELLVGHLGQIFIQN-FVAGDD 1415
Query: 1281 EDYLNPPVIDRMDVQLTKLTLY 1302
E DR+ V++ + LY
Sbjct: 1416 ESR-----SDRLQVEIKDIKLY 1432
Score = 144 bits (362), Expect = 2e-33
Identities = 139/573 (24%), Positives = 260/573 (45%), Gaps = 61/573 (10%)
Query: 3184 LSGIQIEFKQSSHQRSLRARLYWLQVDNQLPGAMFPVVFHPVAPPKSIALDSEPKPFIDV 3243
L+GI + + Q + L + +QVDNQL G P + + V P + E P + V
Sbjct: 3854 LTGINVHYTQLATSHMLELSIQDVQVDNQLIGTTQPFMLY-VTPLSNENEVIETGPAVQV 3912
Query: 3244 SVITRFNEYSKVLQFKYFMVLIQEMALKIDQGFLGAIIALFTPTTDPEAERRRTKLIQQD 3303
+ + ++ + +K+ M+ Q ++I++ L +++ F E+E +++
Sbjct: 3913 NAVKFPSKSALTNIYKHLMITAQRFTVQIEEKLLLKLLSFFG-YDQAESE------VEKY 3965
Query: 3304 IDALNAELMETSMTDMSILSFFEHFHISPVKLHLSLSLGSGGEESDKEKQEMFAVHSVNL 3363
+ L+ + E T I +FE+ IS ++ LS+ S+K ++ A+ S
Sbjct: 3966 DENLHEKTAEQGGTP--IRYYFENLKISIPQIKLSVFT------SNKLPLDLKALKS--- 4014
Query: 3364 LLKSIGATLTDVDDLIFKLAYYEIRYQFYKRDQLIWSVVRHYSEQFLKQMYVLVLGLDVL 3423
++G L +D + L + + + ++ +I +++H+ E+ L Q ++ +D L
Sbjct: 4015 ---TLGFPLIRFEDAVINLDPFTRVHPYETKEFIINDILKHFQEELLSQAARILGSVDFL 4071
Query: 3424 GNPFGLIRGLSEGVEALFYEPFQGAVQGPEEFAEGLVIGVRSLFGHTVGGAAGVVSRITG 3483
GNP GL+ +SEGV L G V G L + G + ++ G
Sbjct: 4072 GNPMGLLNDVSEGVTGLIK---YGNVGG--------------LIRNVTHGVSNSAAKFAG 4114
Query: 3484 SVGKGLAAITMDKEYQQKRREELSRQPRDFGDSLARGGKGFLRGVVGGVTGIITKPVEGA 3543
++ GL TMD +Q + RE + G+ L G G G++GG+T +IT VEG
Sbjct: 4115 TLSDGLGK-TMDNRHQSE-REYIRYHAATSGEHLVAGIHGLAHGIIGGLTSVITSTVEGV 4172
Query: 3544 KKE-GAAGFFKGIGKGLVGAVARPTGGIVDMASSTFQGIQRAAEST---EEVSSLRPPR- 3598
K E G +GF G+GKGLVG V +P G +D AS T Q ++ A + + +R PR
Sbjct: 4173 KTEGGVSGFISGLGKGLVGTVTKPVAGALDFASETAQAVRDTATLSGPRTQAQRVRKPRC 4232
Query: 3599 LIHEDGIIRPYDRQESEGSDLLENHIKKLEGETYRYHCAIPGSKKTILMVTNRRVLCIKE 3658
G++ Y ++EG + L ++ E + A+ ++++++ V +K
Sbjct: 4233 CTGPQGLLPRYSESQAEGQEQLFKLTDNIQDE---FFIAVENIDSYCVLISSKAVYFLKS 4289
Query: 3659 VEILGLMCVDWQCPFEDFVFPPSVSENVLKISVKEQGLFHKKDSANQGC--------VRK 3710
+ + + + ++D ++ VS++ K+ V+ + K S + G
Sbjct: 4290 GDYVDREAIFLEVKYDD-LYHCLVSKDHGKVYVQ---VTKKAVSTSSGVSIPGPSHQKPM 4345
Query: 3711 VYLKDTATAERACNAIEDAQSTRQQQKLMKQSS 3743
V++K A + I A+S +Q+LM + S
Sbjct: 4346 VHVKSEVLAVKLSQEINYAKSLYYEQQLMLRLS 4378
Score = 84.3 bits (207), Expect = 2e-15
Identities = 65/289 (22%), Positives = 140/289 (48%), Gaps = 17/289 (5%)
Query: 990 LLKVEYIKADKNGPSFQTAFGKTEQTVKVAFSSLNLLLQTQALVASINYLTTIIPSDDQS 1049
L+ + DK P F +++ + +++ V F+ L++L+ Q V +++ +D+ +
Sbjct: 1784 LVHINIFLVDKKHPEFSSSYNRVNRSIDVDFNCLDVLITLQTWVVILDFFGIGSTADNHA 1843
Query: 1050 ISVAKEVQISTEKQQKNSTLPKAIVSSRDSDIIDFRLFAKLNAFCVIVCNEKNNIAEIKI 1109
+ + E + K + P A + S D ++ +L K+++ +++ + +A+ +
Sbjct: 1844 MRLPPEGILHNVKLE-----PHASMESGLQDPVNTKLDLKVHSLSLVLNKTTSELAKANV 1898
Query: 1110 QGLDSSLSLQSRKQSLFARLENIIVTDVDPK-TVHKKAVSIMGNEVFRFNLDLY--PDAT 1166
L + L + +L + ++ ++D+ +++ + G E F Y PD
Sbjct: 1899 SKLVAHLEMIEGDLALQGSIGSLSLSDLTCHGEFYRERFTTSGEEALIFQTFKYGRPDPL 1958
Query: 1167 EGDLYTDMSKVDGVLSLNVGCIQIVYLHKFLMSLLNFLNNFQTAKESLSAATAQAAERAA 1226
+ D +SL + +Q V+ +F ++ F+ +F ++ L Q A
Sbjct: 1959 L------RREHDIRVSLRMASVQYVHTQRFQAEVVAFIQHFTQLQDVLGR---QRAAIEG 2009
Query: 1227 TSVKDLAQRSFRVSINIDLKAPVIVIPQSSISTNAVVVDLGLIRVHNQF 1275
+V+D AQR RV ++I+ APV++IP+SS S N +V +LG ++V N+F
Sbjct: 2010 QTVRDQAQRCSRVLLDIEAGAPVLLIPESSRSNNLIVANLGKLKVKNKF 2058
Score = 82.8 bits (203), Expect = 6e-15
Identities = 66/305 (21%), Positives = 147/305 (48%), Gaps = 20/305 (6%)
Query: 1490 EPLHIINSSNVTDEPLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLHLEALLS 1549
EP ++ S D+ L+ + + D PEF + ++ + + V F LD+++ L+ +
Sbjct: 1770 EPKILVGKSKF-DDSLVHINIFLVDKKHPEFSSSYNRVNRSIDVDFNCLDVLITLQTWVV 1828
Query: 1550 FMDFLSSAAPFSEPSSSEKESELKPLVGESRSIAVKAVSSNISQ-KDVFDLKITAELNAF 1608
+DF F S+++ + P G ++ ++ +S S +D + K+ ++++
Sbjct: 1829 ILDF------FGIGSTADNHAMRLPPEGILHNVKLEPHASMESGLQDPVNTKLDLKVHSL 1882
Query: 1609 NVFVCDQKCNIADIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQS-IHKKAVSILGD 1667
++ + +A + + A + + + + + + ++ +++ + G+
Sbjct: 1883 SLVLNKTTSELAKANVSKLVAHLEMIEGDLALQGSIGSLSLSDLTCHGEFYRERFTTSGE 1942
Query: 1668 EVFRFQLTLY--PDATEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQTA 1725
E FQ Y PD + D ++S ++ +Q V+ +F ++ F+ +F
Sbjct: 1943 EALIFQTFKYGRPDPLLRREH------DIRVSLRMASVQYVHTQRFQAEVVAFIQHFTQL 1996
Query: 1726 KEALSTATVQAAERAASSMKDLAQKSFRLLMDINLKAPVIIIPQSSVSPNAVIADLGLIR 1785
++ L Q A +++D AQ+ R+L+DI APV++IP+SS S N ++A+LG ++
Sbjct: 1997 QDVLGR---QRAAIEGQTVRDQAQRCSRVLLDIEAGAPVLLIPESSRSNNLIVANLGKLK 2053
Query: 1786 VENKF 1790
V+NKF
Sbjct: 2054 VKNKF 2058
Score = 53.9 bits (128), Expect = 3e-06
Identities = 96/441 (21%), Positives = 173/441 (39%), Gaps = 70/441 (15%)
Query: 2662 YIIHLYPSLTLRNLLPYSLRYLLEGTAETHELAEGSTADVLHSRISGEIMEL-------- 2713
+ I+L P++ + NLLP L + ++G L G A LH+ + + +EL
Sbjct: 3176 HTIYLLPTVVICNLLPCELDFYVKGMPINGTLKPGKEA-ALHTADTSQNIELGVSLENFP 3234
Query: 2714 ----VLVKYQGKNWNGHFRIRDTLPEFFPVCFSSDSTEVTTVDLSVHVRRIGSRMVLSVF 2769
+L+ +N+ R+ D + + + + R GS + +
Sbjct: 3235 LCKELLIPPGTQNYMVRMRLYDV------------NRRQLNLTIRIVCRAEGSLKIF-IS 3281
Query: 2770 SPYWLINKTTRVLQYRSEDIHVKHPADFRD--------IILFSFKKKNIFTKNKVQLKIS 2821
+PYWLINKT L +R ++ F + +LF + K N ++I
Sbjct: 3282 APYWLINKTGLPLIFRQDNAKTDAAGQFEEHELARSLSPLLFCYADKE--QPNLCTMRIG 3339
Query: 2822 TS-------AWSSSFSLDTVGSYGCVKCPAN----NMEYLVGVSIK--MSSFNLSRIVTL 2868
W FSLD +K + Y +G+ +K + + +V
Sbjct: 3340 RGIHPEGMPGWCQGFSLDGGSGVRALKVIQQGNRPGLIYNIGIDVKKGRGRYIDTCMVIF 3399
Query: 2869 TPFCTIANKSSLELEVGEIA-SDGSMPTNKWNYIAS---SECLPFWPES-LSGKLCVR-- 2921
P + NKSS +L + + G N YI++ S + WP + LCVR
Sbjct: 3400 APRYLLDNKSSHKLAFAQREFARGQGTANPEGYISTLPGSSVVFHWPRNDYDQLLCVRLM 3459
Query: 2922 -VVGCEGSSKPFFYNRQDNGTLLSLEDLNGG---ILVDVNTAEHSTVITFSDYHEGSAPA 2977
V C S F ++N +++ D G + V++ + I+FSD + P
Sbjct: 3460 DVPNCIWSGG--FEVNKNNSFHINMRDTLGKCFFLRVEITLRGATYRISFSDTDQLPPPF 3517
Query: 2978 LIMNHTPWDILTYKQSGSPEEMV---LLPRQARLFAWADPTGTRKLTWTYAANVGEHDLL 3034
I N + ++ + Q G E + + P + +AW +PT +T T G ++
Sbjct: 3518 RIDNFSKVPVV-FTQHGVAEPRLRTEVKPMTSLDYAWDEPTLPPFITLT-VKGAGSSEI- 3574
Query: 3035 KDGCGQFPYDANIQIHWVSFL 3055
C + N Q+++ +F+
Sbjct: 3575 --NCNMNDFQDNRQLYYENFI 3593
Score = 52.0 bits (123), Expect = 1e-05
Identities = 122/611 (19%), Positives = 236/611 (38%), Gaps = 138/611 (22%)
Query: 1317 LLHPINLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLNQEDLNLL---FRILT--ENL 1371
++ N+ + R L + K P + G+L + + +N++ ++ L F +LT E
Sbjct: 848 VVEKFNVHLQLERRLIYTSDPKYPGAVLSGNLPDLKIHINEDKISALKNCFALLTTPEMK 907
Query: 1372 CEGTEDLDKVKPRVQETGEIKEPLEISISQDVHDSKNTLTTGVEEIRSVDIINMLLNFEI 1431
T+ +K+ P+ ++ G S+ V + ++ + R V + + LL E
Sbjct: 908 TSDTQIKEKIFPQEEQRG--------SLQDSVMNLTQSIVLLEQHTREVLVESQLLLAEF 959
Query: 1432 KEVVVTLMKKSEKKGRPLHELNVLQLGMEAKVKTYD----MTAKAYLKKISMQCF--DFT 1485
K V + E GR + L V + YD +T L +MQ + DF
Sbjct: 960 K--VNCMQLGVESNGRYISVLKVFGTNAHFVKRPYDAEVSLTVHGLLLVDTMQTYGADFD 1017
Query: 1486 -------------------DSKGE-PLHIINSSNVTD----------------------E 1503
DS+ + P+ N +++TD E
Sbjct: 1018 LLMASHKNLSFDIPTGSLRDSRAQSPVSGPNVAHLTDGATLNDRSATSVSLDKILTKEQE 1077
Query: 1504 PLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLHLEALLSFMDFLSSAAPFSEP 1563
L+K+ S+ P DST Q + + +LD++L+ E ++ + FL + P +
Sbjct: 1078 SLIKLEYQFVSSECPSMNL--DSTLQVISLQVNNLDIILNPETIVELIGFLQKSFPKEKD 1135
Query: 1564 SSSEKESELKPLVGE-SRSIAVKAVSSNISQKDVFDLKITAELNAFNVFVC--------- 1613
S + PL+ + RS + + +++ ++ E++ N+ +
Sbjct: 1136 DLSPQ-----PLMTDFERSFREQGTYQSTYEQNT---EVAVEIHRLNLLLLRTVGMANRE 1187
Query: 1614 DQKCNIADIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQSIHKKAVSILGDEV---- 1669
IA I G ++S+ D+ L + +M++ ++ + V +G+ V
Sbjct: 1188 KYGRKIATASIGGTKVNVSMG-STFDMNGSLGCLQLMDLTQDNVKNQYVVSIGNSVGYEN 1246
Query: 1670 -------FRFQLTLYPDATEGEA----YADMSKVDGKLSFKVGCIQIVYVHKFF----MS 1714
F DA EA + + SK + L+ K+ + + KF +S
Sbjct: 1247 IISDIGYFESVFVRMEDAALTEALSFTFVERSKQECFLNLKMASLHYNHSAKFLKELTLS 1306
Query: 1715 LLNFLNNFQTAKEALST--ATVQAAERAASSMK------------------------DLA 1748
+ NF+ ++ +T TV A + A S DLA
Sbjct: 1307 MDELEENFRGMLKSAATKVTTVLATKTAEYSEMVSLFETPRKTREPFILEENEIYGFDLA 1366
Query: 1749 QK---SFRLLMDINLKAPVIIIPQSSVSPNAVIADLGLIRVENKFSLVPMEHYSLPPVID 1805
+ +L+++IN+++PV+ IP+ SP ++ LG I ++N F E S D
Sbjct: 1367 SSHLDTVKLILNINIESPVVSIPRKPGSPELLVGHLGQIFIQN-FVAGDDESRS-----D 1420
Query: 1806 KMNIELTQLKL 1816
++ +E+ +KL
Sbjct: 1421 RLQVEIKDIKL 1431
Score = 39.7 bits (91), Expect = 0.057
Identities = 86/375 (22%), Positives = 148/375 (39%), Gaps = 50/375 (13%)
Query: 1317 LLHPINLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLNQEDLNLLFRILTENLCEGTE 1376
L P L+ V RNL H VP + I G+L S++ SL+ L+ +L NL E E
Sbjct: 2201 LTEPCRLKLQVERNLDKEISHTVPDISIHGNLSSVHCSLDLYKYKLIRGLLENNLGEPIE 2260
Query: 1377 DLDKVKPRVQETGEIKEP-LEISISQDVHDSKNTLTTGVEEIRSVDIINMLLNF---EIK 1432
+ ++P ++++P + +S +V+ L +D++N+ L + K
Sbjct: 2261 EF--MRPY-----DLQDPRIHTVLSGEVYTCMCFL---------IDMVNVSLELKDPKRK 2304
Query: 1433 EVVVTLMKKSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFD--FTDSKGE 1490
E +L + KK + L+E + T L SM FD + K
Sbjct: 2305 EGAGSLARFDFKKCKLLYE------------SFSNQTKSINLVSHSMMAFDTRYAGQKTS 2352
Query: 1491 PLHIINSSNVTDEPLLKMLLTKADSD-GPEFKTIHDSTKQRLKVSFASLDLVLHLEALLS 1549
P + N + +P T+ F++ DS+ V +L + L + LL
Sbjct: 2353 P-GMTNVFSCIFQPAKNSSTTQGSIQIELHFRSTKDSS--CFTVVLNNLRVFLIFDWLLL 2409
Query: 1550 FMDFLSSAAPF--------SEPSSSEKESELKPLVGESRSIAVKAVSSNISQKDVFDLKI 1601
DFL + + S +S ES + P +S + K S +S + ++K+
Sbjct: 2410 VHDFLHTPSDIKKQNHVTPSRHRNSSSESAIVPKTVKS-GVVTKRSSLPVSNERHLEVKV 2468
Query: 1602 TAELNAFNVFVCDQKCNIADIKIHGMDASISVKPKQTD--VFARLKDIIVMNVDLQSIHK 1659
F V + D C + I ++ KP+ D L I V + L + H
Sbjct: 2469 NVTGTEF-VVIEDVSCFDTNAIILKGTTVLTYKPRFVDRPFSGSLFGIEVFSCRLGNEHD 2527
Query: 1660 KAVSILGDEVFRFQL 1674
A+SI+ + +L
Sbjct: 2528 TALSIVDPVQIQMEL 2542
>gi|35493713 vacuolar protein sorting 13B isoform 5 [Homo sapiens]
Length = 4022
Score = 107 bits (268), Expect = 2e-22
Identities = 69/264 (26%), Positives = 121/264 (45%), Gaps = 13/264 (4%)
Query: 3352 KQEMFAVHSVNLLLKSIGATLT---DVDDLIFKLAYYEIRYQFYKRDQLIWSVVRHYSEQ 3408
K + VNLL+ SI A+L D + +E F QL+ ++ HY+
Sbjct: 3584 KLRKLVIQPVNLLV-SIHASLKLYIASDHTPLSFSVFERGPIFTTARQLVHALAMHYAAG 3642
Query: 3409 FLKQMYVLVLGLDVLGNPFGLIRGLSEGVEALFYEPFQGAVQGPEEFAEGLVIGVRSLFG 3468
L + +V LD+LG+P L+R + GV F P++G +GP F G+ G S
Sbjct: 3643 ALFRAGWVVGSLDILGSPASLVRSIGNGVADFFRLPYEGLTRGPGAFVSGVSRGTTSFVK 3702
Query: 3469 HTVGGAAGVVSRITGSVGKGLAAITMDKEYQQKRREELSRQPRDFGDSLARGGKGFLRGV 3528
H G ++ + S+ + + +++D+E+ ++ E + P G+ L +G +
Sbjct: 3703 HISKGTLTSITNLATSLARNMDRLSLDEEHYNRQEEWRRQLPESLGEGLRQGLSRLGISL 3762
Query: 3529 VGGVTGIITKPVEGAKKEG---------AAGFFKGIGKGLVGAVARPTGGIVDMASSTFQ 3579
+G + GI+ +P++ +K A G G+GKG++G +P GG ++ S T
Sbjct: 3763 LGAIAGIVDQPMQNFQKTSEAQASAGHKAKGVISGVGKGIMGVFTKPIGGAAELVSQTGY 3822
Query: 3580 GIQRAAESTEEVSSLRPPRLIHED 3603
GI A ++ P +H D
Sbjct: 3823 GILHGAGLSQLPKQRHQPSDLHAD 3846
Score = 71.6 bits (174), Expect = 1e-11
Identities = 66/253 (26%), Positives = 111/253 (43%), Gaps = 54/253 (21%)
Query: 2 VLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENAL-SELDVPFKVKAG 60
+LES V +L ++ Y++NL S L+L +WGG+V L L++K + L EL +PF +G
Sbjct: 1 MLESYVTPILMSYVNRYIKNLKPSDLQLSLWGGDVVLSKLELKLDVLEQELKLPFTFLSG 60
Query: 61 QIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEE 120
I +L + +PW L E VV T+ + + +K + +QD + S
Sbjct: 61 HIHELRIHVPWTKLGSEPVVITINTMECI-----------LKLKDGIQDDHE---SCGSN 106
Query: 121 ALQKAAEKGTHSGEFIYGLENFVYKDIKPGRKRKKHKKHFKKPFKGLDRSKDKPKEAKKD 180
+ ++ + T S IKP R + + D P
Sbjct: 107 STNRSTAESTKS-------------SIKPRRMQ-----------QAAPTDPDLP-----P 137
Query: 181 TFVEKLATQVIKNVQVKITDIHIKY-EDDVTDPKRPLSFGVTLGELSLLTANEHWTPCI- 238
+V+ L +V+ NV + I ++ +KY EDD+ LS +T E T E W
Sbjct: 138 GYVQSLIRRVVNNVNIVINNLILKYVEDDIV-----LSVNITSAE--CYTVGELWDRAFM 190
Query: 239 -LNEADKIIYKLI 250
++ D ++ K+I
Sbjct: 191 DISATDLVLRKVI 203
>gi|35493701 vacuolar protein sorting 13B isoform 1 [Homo sapiens]
Length = 3997
Score = 107 bits (268), Expect = 2e-22
Identities = 69/264 (26%), Positives = 121/264 (45%), Gaps = 13/264 (4%)
Query: 3352 KQEMFAVHSVNLLLKSIGATLT---DVDDLIFKLAYYEIRYQFYKRDQLIWSVVRHYSEQ 3408
K + VNLL+ SI A+L D + +E F QL+ ++ HY+
Sbjct: 3559 KLRKLVIQPVNLLV-SIHASLKLYIASDHTPLSFSVFERGPIFTTARQLVHALAMHYAAG 3617
Query: 3409 FLKQMYVLVLGLDVLGNPFGLIRGLSEGVEALFYEPFQGAVQGPEEFAEGLVIGVRSLFG 3468
L + +V LD+LG+P L+R + GV F P++G +GP F G+ G S
Sbjct: 3618 ALFRAGWVVGSLDILGSPASLVRSIGNGVADFFRLPYEGLTRGPGAFVSGVSRGTTSFVK 3677
Query: 3469 HTVGGAAGVVSRITGSVGKGLAAITMDKEYQQKRREELSRQPRDFGDSLARGGKGFLRGV 3528
H G ++ + S+ + + +++D+E+ ++ E + P G+ L +G +
Sbjct: 3678 HISKGTLTSITNLATSLARNMDRLSLDEEHYNRQEEWRRQLPESLGEGLRQGLSRLGISL 3737
Query: 3529 VGGVTGIITKPVEGAKKEG---------AAGFFKGIGKGLVGAVARPTGGIVDMASSTFQ 3579
+G + GI+ +P++ +K A G G+GKG++G +P GG ++ S T
Sbjct: 3738 LGAIAGIVDQPMQNFQKTSEAQASAGHKAKGVISGVGKGIMGVFTKPIGGAAELVSQTGY 3797
Query: 3580 GIQRAAESTEEVSSLRPPRLIHED 3603
GI A ++ P +H D
Sbjct: 3798 GILHGAGLSQLPKQRHQPSDLHAD 3821
Score = 71.6 bits (174), Expect = 1e-11
Identities = 66/253 (26%), Positives = 111/253 (43%), Gaps = 54/253 (21%)
Query: 2 VLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENAL-SELDVPFKVKAG 60
+LES V +L ++ Y++NL S L+L +WGG+V L L++K + L EL +PF +G
Sbjct: 1 MLESYVTPILMSYVNRYIKNLKPSDLQLSLWGGDVVLSKLELKLDVLEQELKLPFTFLSG 60
Query: 61 QIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEE 120
I +L + +PW L E VV T+ + + +K + +QD + S
Sbjct: 61 HIHELRIHVPWTKLGSEPVVITINTMECI-----------LKLKDGIQDDHE---SCGSN 106
Query: 121 ALQKAAEKGTHSGEFIYGLENFVYKDIKPGRKRKKHKKHFKKPFKGLDRSKDKPKEAKKD 180
+ ++ + T S IKP R + + D P
Sbjct: 107 STNRSTAESTKS-------------SIKPRRMQ-----------QAAPTDPDLP-----P 137
Query: 181 TFVEKLATQVIKNVQVKITDIHIKY-EDDVTDPKRPLSFGVTLGELSLLTANEHWTPCI- 238
+V+ L +V+ NV + I ++ +KY EDD+ LS +T E T E W
Sbjct: 138 GYVQSLIRRVVNNVNIVINNLILKYVEDDIV-----LSVNITSAE--CYTVGELWDRAFM 190
Query: 239 -LNEADKIIYKLI 250
++ D ++ K+I
Sbjct: 191 DISATDLVLRKVI 203
>gi|119874215 vacuolar protein sorting 13B isoform 4 [Homo sapiens]
Length = 415
Score = 71.6 bits (174), Expect = 1e-11
Identities = 66/253 (26%), Positives = 111/253 (43%), Gaps = 54/253 (21%)
Query: 2 VLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENAL-SELDVPFKVKAG 60
+LES V +L ++ Y++NL S L+L +WGG+V L L++K + L EL +PF +G
Sbjct: 1 MLESYVTPILMSYVNRYIKNLKPSDLQLSLWGGDVVLSKLELKLDVLEQELKLPFTFLSG 60
Query: 61 QIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEE 120
I +L + +PW L E VV T+ + + +K + +QD + S
Sbjct: 61 HIHELRIHVPWTKLGSEPVVITINTMECI-----------LKLKDGIQDDHE---SCGSN 106
Query: 121 ALQKAAEKGTHSGEFIYGLENFVYKDIKPGRKRKKHKKHFKKPFKGLDRSKDKPKEAKKD 180
+ ++ + T S IKP R + + D P
Sbjct: 107 STNRSTAESTKS-------------SIKPRRMQ-----------QAAPTDPDLP-----P 137
Query: 181 TFVEKLATQVIKNVQVKITDIHIKY-EDDVTDPKRPLSFGVTLGELSLLTANEHWTPCI- 238
+V+ L +V+ NV + I ++ +KY EDD+ LS +T E T E W
Sbjct: 138 GYVQSLIRRVVNNVNIVINNLILKYVEDDIV-----LSVNITSAE--CYTVGELWDRAFM 190
Query: 239 -LNEADKIIYKLI 250
++ D ++ K+I
Sbjct: 191 DISATDLVLRKVI 203
>gi|35493725 vacuolar protein sorting 13B isoform 3 [Homo sapiens]
Length = 863
Score = 71.6 bits (174), Expect = 1e-11
Identities = 66/253 (26%), Positives = 111/253 (43%), Gaps = 54/253 (21%)
Query: 2 VLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENAL-SELDVPFKVKAG 60
+LES V +L ++ Y++NL S L+L +WGG+V L L++K + L EL +PF +G
Sbjct: 1 MLESYVTPILMSYVNRYIKNLKPSDLQLSLWGGDVVLSKLELKLDVLEQELKLPFTFLSG 60
Query: 61 QIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEE 120
I +L + +PW L E VV T+ + + +K + +QD + S
Sbjct: 61 HIHELRIHVPWTKLGSEPVVITINTMECI-----------LKLKDGIQDDHE---SCGSN 106
Query: 121 ALQKAAEKGTHSGEFIYGLENFVYKDIKPGRKRKKHKKHFKKPFKGLDRSKDKPKEAKKD 180
+ ++ + T S IKP R + + D P
Sbjct: 107 STNRSTAESTKS-------------SIKPRRMQ-----------QAAPTDPDLP-----P 137
Query: 181 TFVEKLATQVIKNVQVKITDIHIKY-EDDVTDPKRPLSFGVTLGELSLLTANEHWTPCI- 238
+V+ L +V+ NV + I ++ +KY EDD+ LS +T E T E W
Sbjct: 138 GYVQSLIRRVVNNVNIVINNLILKYVEDDIV-----LSVNITSAE--CYTVGELWDRAFM 190
Query: 239 -LNEADKIIYKLI 250
++ D ++ K+I
Sbjct: 191 DISATDLVLRKVI 203
>gi|118197272 ATG2 autophagy related 2 homolog B [Homo sapiens]
Length = 2078
Score = 44.3 bits (103), Expect = 0.002
Identities = 26/88 (29%), Positives = 47/88 (53%), Gaps = 5/88 (5%)
Query: 10 LLNRFLGDYV-ENLNKSQLKLGIWGGNVALDNLQIKENALSEL----DVPFKVKAGQIDK 64
LL R+LG ++ E L+ QL L ++ G +L + + + L+E+ D P +V G I
Sbjct: 17 LLQRYLGHFLQEKLSLEQLSLDLYQGTGSLAQVPLDKWCLNEILESADAPLEVTEGFIQS 76
Query: 65 LTLKIPWKNLYGEAVVATLEGLYLLVVP 92
++L +PW +L + + GL ++ P
Sbjct: 77 ISLSVPWGSLLQDNCALEVRGLEMVFRP 104
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 41.2 bits (95), Expect = 0.020
Identities = 33/141 (23%), Positives = 69/141 (48%), Gaps = 19/141 (13%)
Query: 385 HIRRYTQMWSWSNIKKHRQLLKSYKIAYKNKLTQSKV------SEEIQKEIQDLEKTLDV 438
+I + T+ +++ +R + ++ KN Q K+ EIQ ++DL++ L+
Sbjct: 191 YIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLER 250
Query: 439 FNIILARQQAQVEVIRSGQKLRKKSADTG---EKRGGW-------FSGLWGKKESKKKDE 488
++L +QQ QVE R G++L+ SA E+ W +W ++E ++ E
Sbjct: 251 AQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQE 310
Query: 489 ESLIPETIDDLMTPEEKDKLF 509
E + + +L E+++K++
Sbjct: 311 EKMCEQ---ELKIREQEEKMW 328
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 40.8 bits (94), Expect = 0.026
Identities = 33/141 (23%), Positives = 69/141 (48%), Gaps = 19/141 (13%)
Query: 385 HIRRYTQMWSWSNIKKHRQLLKSYKIAYKNKLTQSKV------SEEIQKEIQDLEKTLDV 438
+I + T+ +++ +R + ++ KN Q K+ EIQ ++DL++ L+
Sbjct: 191 YIEKLTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLER 250
Query: 439 FNIILARQQAQVEVIRSGQKLRKKSADTG---EKRGGW-------FSGLWGKKESKKKDE 488
++L +QQ QVE R G++L+ SA E+ W +W ++E ++ E
Sbjct: 251 AQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQE 310
Query: 489 ESLIPETIDDLMTPEEKDKLF 509
E + + +L E+++K++
Sbjct: 311 EKMCEQ---ELKIREQEEKMW 328
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 38.1 bits (87), Expect = 0.17
Identities = 29/102 (28%), Positives = 54/102 (52%), Gaps = 3/102 (2%)
Query: 406 KSYKIAYKNKLTQSKVSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKSA- 464
K+ K+ K +L +S+ SE IQ +++L++ L+ ++L +QQ Q E G++L+ SA
Sbjct: 210 KNAKLQEKLQLVESEKSE-IQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAK 268
Query: 465 -DTGEKRGGWFSGLWGKKESKKKDEESLIPETIDDLMTPEEK 505
+ ++ L ++E K +E I E + + EEK
Sbjct: 269 LQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEK 310
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 37.7 bits (86), Expect = 0.22
Identities = 29/102 (28%), Positives = 54/102 (52%), Gaps = 3/102 (2%)
Query: 406 KSYKIAYKNKLTQSKVSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKSA- 464
K+ K+ K +L +S+ SE IQ +++L++ L+ ++L +QQ Q E G++L+ SA
Sbjct: 222 KNAKLQEKLQLVESEKSE-IQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAK 280
Query: 465 -DTGEKRGGWFSGLWGKKESKKKDEESLIPETIDDLMTPEEK 505
+ ++ L ++E K +E I E + + EEK
Sbjct: 281 LQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEK 322
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 37.7 bits (86), Expect = 0.22
Identities = 29/102 (28%), Positives = 54/102 (52%), Gaps = 3/102 (2%)
Query: 406 KSYKIAYKNKLTQSKVSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKSA- 464
K+ K+ K +L +S+ SE IQ +++L++ L+ ++L +QQ Q E G++L+ SA
Sbjct: 222 KNAKLQEKLQLVESEKSE-IQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAK 280
Query: 465 -DTGEKRGGWFSGLWGKKESKKKDEESLIPETIDDLMTPEEK 505
+ ++ L ++E K +E I E + + EEK
Sbjct: 281 LQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEK 322
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 37.7 bits (86), Expect = 0.22
Identities = 29/102 (28%), Positives = 54/102 (52%), Gaps = 3/102 (2%)
Query: 406 KSYKIAYKNKLTQSKVSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKSA- 464
K+ K+ K +L +S+ SE IQ +++L++ L+ ++L +QQ Q E G++L+ SA
Sbjct: 283 KNAKLQEKLQLVESEKSE-IQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAK 341
Query: 465 -DTGEKRGGWFSGLWGKKESKKKDEESLIPETIDDLMTPEEK 505
+ ++ L ++E K +E I E + + EEK
Sbjct: 342 LQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEK 383
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 37.7 bits (86), Expect = 0.22
Identities = 43/207 (20%), Positives = 87/207 (42%), Gaps = 24/207 (11%)
Query: 1346 GHLDSMNVSLNQEDLNLLFRILTENLCEGTEDLDK---------------VKPRVQETGE 1390
G L +N SLNQE +NL+ + +E+ ++ +K + R +ETG
Sbjct: 977 GTLKEINASLNQEKMNLIQK--SESFANYIDEREKSISELSDQYKQEKLILLQRCEETGN 1034
Query: 1391 IKEPL--EISISQDVHDSKNTLT---TGVEEIRSVDIINMLLNF--EIKEVVVTLMKKSE 1443
E L + +Q+ + L T + E R ++ + F E +E + L E
Sbjct: 1035 AYEDLSQKYKAAQEKNSKLECLLNECTSLCENRKNELEQLKEAFAKEHQEFLTKLAFAEE 1094
Query: 1444 KKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFDFTDSKGEPLHIINSSNVTDE 1503
+ + EL +Q + +++ +K+ + + + + + +N +E
Sbjct: 1095 RNQNLMLELETVQQALRSEMTDNQNNSKSEAGGLKQEIMTLKEEQNKMQKEVNDLLQENE 1154
Query: 1504 PLLKMLLTKADSDGPEFKTIHDSTKQR 1530
L+K++ TK + E + I +S K+R
Sbjct: 1155 QLMKVMKTKHECQNLESEPIRNSVKER 1181
>gi|13699824 kinesin family member 11 [Homo sapiens]
Length = 1056
Score = 37.4 bits (85), Expect = 0.28
Identities = 73/355 (20%), Positives = 144/355 (40%), Gaps = 58/355 (16%)
Query: 413 KNKLTQSKVSEEIQKEIQDLEKT---LDVFNIILARQQAQVEVIRSGQK----LRKKSAD 465
KN+L Q K ++Q + Q+LE T L + L +++ + S ++ K +
Sbjct: 444 KNELDQCK--SDLQNKTQELETTQKHLQETKLQLVKEEYITSALESTEEKLHDAASKLLN 501
Query: 466 TGEKRGGWFSGLWGKKESKKK------DEESLIPETIDDLMTPEEKDKLFTAIGYSESTH 519
T E+ SGL K + KK + + + + ++ L E+ G S+
Sbjct: 502 TVEETTKDVSGLHSKLDRKKAVDQHNAEAQDIFGKNLNSLFNNMEE---LIKDGSSKQKA 558
Query: 520 NLTLPKQYVAHIMTLKLVS----TSVTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKV 575
L + K ++++ + + T+V + +IPE + + + + + Q+L
Sbjct: 559 MLEVHKTLFGNLLSSSVSALDTITTVALGSLTSIPENVSTHVSQIFNMILKE---QSLAA 615
Query: 576 EAKLEHWYITGLRQQDIVPSLVASIGDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVI 635
E+K + + + D++ SL + T S+LKI SQ +
Sbjct: 616 ESKTVLQELINVLKTDLLSSLEMILSPTVVSILKI-----------------NSQLKHIF 658
Query: 636 YDAKTVNAVVEFFQSNKGLDLEQITSATLMKLEEIKERTATGLTHIIETRKVLDLRINLK 695
+ TV +E ++ +L+ S L E++E T + ++E++K NL
Sbjct: 659 KTSLTVADKIE----DQKKELDGFLSILCNNLHELQENT---ICSLVESQKQCG---NLT 708
Query: 696 PSYLVVPQTGFHHEKSDLLILDFGTFQ---LNSKDQGLQKTTNSSLEEIMDKAYD 747
+ QT H + +++ T + L K + +QK +S E I K+ D
Sbjct: 709 EDLKTIKQT---HSQELCKLMNLWTERFCALEEKCENIQKPLSSVQENIQQKSKD 760
>gi|239746976 PREDICTED: similar to paraneoplastic antigen MA1 [Homo
sapiens]
Length = 601
Score = 36.6 bits (83), Expect = 0.48
Identities = 36/114 (31%), Positives = 44/114 (38%), Gaps = 30/114 (26%)
Query: 3447 GAVQGPEEFAEGLVIGVRSLFGHTVGGAAGVVSRITGSVGKGLAAITMDKEYQQKRREEL 3506
G QGP+ EG G RSL G G V+ + G+VG+
Sbjct: 67 GPAQGPQREEEGAP-GCRSLVGRGWGVGWAAVAEVQGTVGE------------------- 106
Query: 3507 SRQPRDFGDSLARGGKGFLRGVVGGVTG---IITKPVEGAKKEGAAGFFKGIGK 3557
R FG GG+G L VGG G + K G KEG +F G GK
Sbjct: 107 -RGALAFG-----GGRGLLAAGVGGAEGGCQVTRKIKRGRSKEGGGSWF-GAGK 153
>gi|93204861 protein phosphatase 1, regulatory (inhibitor) subunit 9A
[Homo sapiens]
Length = 1098
Score = 36.6 bits (83), Expect = 0.48
Identities = 92/479 (19%), Positives = 199/479 (41%), Gaps = 54/479 (11%)
Query: 16 GDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAGQIDKLTLKIPWKNLY 75
G+Y + + ++ + G ++A++ ++ EN ++ P ++ ++ ++ K+
Sbjct: 632 GEYATDEEEDEVGPVLPGSDMAIEVFELPEN--EDMFSPSELDTSKLSHKFKELQIKHAV 689
Query: 76 GEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEEALQKAAEKGTHS-GE 134
EA + L+ L ++++ K + + KE E+ A+ H+ E
Sbjct: 690 TEAEIQKLK-TKLQAAENEKVRWELEKTQLQQNIEENKERMLKLESYWIEAQTLCHTVNE 748
Query: 135 FIYGLENFVYKDIKPGRKRKKHKKHFKKPFKGLDRSKDKPKEAKKDTFVEKLATQVIKNV 194
+ ++ K K KK K F++ K LD K + E KK +EK ++ +
Sbjct: 749 HLKETQSQYQALEKKYNKAKKLIKDFQQ--KELDFIKRQEAERKKIEDLEKAHLVEVQGL 806
Query: 195 QVKITDIHIKY-------EDDVTDPKRPLSFGVTLGELSLLTANEH----WTPC---ILN 240
QV+I D+ + V + +LGE+S E+ T C +
Sbjct: 807 QVRIRDLEAEVFRLLKQNGTQVNNNNNIFERRTSLGEVSKGDTMENLDGKQTSCQDGLSQ 866
Query: 241 EADKIIYKLIRLDSLSAYWNVNCSMSYQR---SREQILDQLKNEILTSGNIPPNYQY--I 295
+ ++ + + RLDS + S+ +R SR ++ D + + N+ +
Sbjct: 867 DLNEAVPETERLDSKALKTRAQLSVKNRRQRPSRTRLYDSVSSTDGEDSLERKNFTFNDD 926
Query: 296 FQPISASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKPQYLSMIDLLESVDYMVRNA 355
F P S S+ AE KTP L Q++A L+ + L MID D ++ +
Sbjct: 927 FSPSSTSSADLSGLGAEP--KTPGLS-----QSLA--LSSDESLDMID-----DEILDDG 972
Query: 356 PYRKYKPYLPLHTNGRRWWKYAIDSV----LEVHIRRYTQMWSWSNIKKHRQLLKSYKIA 411
K+ R ++++ V + +++ +Y +S NI + L
Sbjct: 973 QSPKHS-----QCQNRAVQEWSVQQVSHWLMSLNLEQYVSEFSAQNITGEQLLQLDGNKL 1027
Query: 412 YKNKLTQSKVSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKSADTGEKR 470
+T S+ ++K++++++ +L+ ++AQ ++ + +KLR+K + +++
Sbjct: 1028 KALGMTASQDRAVVKKKLKEMKMSLE------KARKAQEKMEKQREKLRRKEQEQMQRK 1080
>gi|169217313 PREDICTED: similar to paraneoplastic antigen MA1 [Homo
sapiens]
Length = 601
Score = 36.2 bits (82), Expect = 0.63
Identities = 36/114 (31%), Positives = 44/114 (38%), Gaps = 30/114 (26%)
Query: 3447 GAVQGPEEFAEGLVIGVRSLFGHTVGGAAGVVSRITGSVGKGLAAITMDKEYQQKRREEL 3506
G QGP+ EG G RSL G G V+ + G+VG+
Sbjct: 67 GPAQGPQREEEGAP-GCRSLVGRGWGVGWAAVAEVQGTVGE------------------- 106
Query: 3507 SRQPRDFGDSLARGGKGFLRGVVGGVTG---IITKPVEGAKKEGAAGFFKGIGK 3557
R FG GG+G L VGG G + K G KEG +F G GK
Sbjct: 107 -RGACAFG-----GGRGLLAAGVGGAEGGCQVTRKIKRGRSKEGGGSWF-GAGK 153
>gi|32880208 diaphanous homolog 3 isoform b [Homo sapiens]
Length = 849
Score = 36.2 bits (82), Expect = 0.63
Identities = 38/156 (24%), Positives = 69/156 (44%), Gaps = 16/156 (10%)
Query: 1093 FCVIVCNEK-----NNIAEIKIQGLDSSLSLQSRKQSL------FARLENIIVTDVDPKT 1141
F V +C EK N + +++ S +S+++ +++L +LE + T P+
Sbjct: 622 FLVEICEEKYPDILNFVDDLEPLDKASKVSVETLEKNLRQMGRQLQQLEKELETFPPPED 681
Query: 1142 VHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMSKV-DGVLSLNVGCIQIVYLHKFLMSL 1200
+H K V+ M V T L+ +M K+ ++ ++ V + FL L
Sbjct: 682 LHDKFVTKMSRFVISAKEQY---ETLSKLHENMEKLYQSIIGYYAIDVKKVSVEDFLTDL 738
Query: 1201 LNFLNNF-QTAKESLSAATAQAAERAATSVKDLAQR 1235
NF F Q KE++ A+ E+ K+LA+R
Sbjct: 739 NNFRTTFMQAIKENIKKREAEEKEKRVRIAKELAER 774
>gi|110225351 diaphanous homolog 3 isoform a [Homo sapiens]
Length = 1193
Score = 36.2 bits (82), Expect = 0.63
Identities = 38/156 (24%), Positives = 69/156 (44%), Gaps = 16/156 (10%)
Query: 1093 FCVIVCNEK-----NNIAEIKIQGLDSSLSLQSRKQSL------FARLENIIVTDVDPKT 1141
F V +C EK N + +++ S +S+++ +++L +LE + T P+
Sbjct: 885 FLVEICEEKYPDILNFVDDLEPLDKASKVSVETLEKNLRQMGRQLQQLEKELETFPPPED 944
Query: 1142 VHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMSKV-DGVLSLNVGCIQIVYLHKFLMSL 1200
+H K V+ M V T L+ +M K+ ++ ++ V + FL L
Sbjct: 945 LHDKFVTKMSRFVISAKEQY---ETLSKLHENMEKLYQSIIGYYAIDVKKVSVEDFLTDL 1001
Query: 1201 LNFLNNF-QTAKESLSAATAQAAERAATSVKDLAQR 1235
NF F Q KE++ A+ E+ K+LA+R
Sbjct: 1002 NNFRTTFMQAIKENIKKREAEEKEKRVRIAKELAER 1037
>gi|51988900 XPG-complementing protein [Homo sapiens]
Length = 1186
Score = 35.8 bits (81), Expect = 0.82
Identities = 54/230 (23%), Positives = 94/230 (40%), Gaps = 31/230 (13%)
Query: 730 LQKTTNSSLEEIMDKAYDKFDVEIKNVQLLFARAEETWKKCRFQHPSTMHILQPMDIHVE 789
LQ+T SS+ + +A D ++NV A+ E + + + +T Q + +
Sbjct: 583 LQET--SSIVSVPSEAVDN----VENVVSFNAKEHENFLETIQEQQTTESAGQDL---IS 633
Query: 790 LAKAMVEKDIRMARFKVSGGLPLMHVRISDQKMKDVLYLMNSIPLPQKSSAQSPERQVSS 849
+ KA+ +I + G + ISD++++ A+ PE +S
Sbjct: 634 IPKAVEPMEIDSEESESDGSFIEVQSVISDEELQ----------------AEFPE---TS 674
Query: 850 IPIISGGTKGLLGTSLLLDTVESES---DDEYFDAEDGEPQTCKSMKGSELKKAAEVPNE 906
P G + L+GT ESES D+ D DGEPQ + L + ++ E
Sbjct: 675 KPPSEQGEEELVGTREGEAPAESESLLRDNSERDDVDGEPQEAEKDAEDSLHEWQDINLE 734
Query: 907 ELINLLLKFEIKEVILEFTKQQKEEDTILVFNVTQLGTEATMRTFDLTVV 956
EL L ++ L+ KQQ+E V L ++ +R F + +
Sbjct: 735 ELETLESNLLAQQNSLKAQKQQQERIAATVTGQMFLESQELLRLFGIPYI 784
>gi|55749659 UHRF1 (ICBP90) binding protein 1-like isoform b [Homo
sapiens]
Length = 522
Score = 34.3 bits (77), Expect = 2.4
Identities = 19/85 (22%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
Query: 3 LESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSE-LDVPFKVKAGQ 61
+ ++ + + L + +NL+ ++ L G L NL++ E L LD+P + +
Sbjct: 1 MAGIIKKQILKHLSRFTKNLSPDKINLSTLKGEGELKNLELDEEVLQNMLDLPTWLAINK 60
Query: 62 I--DKLTLKIPWKNLYGEAVVATLE 84
+ +K +++IPW L + +L+
Sbjct: 61 VFCNKASIRIPWTKLKTHPICLSLD 85
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.134 0.380
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 128,679,341
Number of Sequences: 37866
Number of extensions: 5560110
Number of successful extensions: 16081
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 36
Number of HSP's that attempted gapping in prelim test: 15625
Number of HSP's gapped (non-prelim): 246
length of query: 3753
length of database: 18,247,518
effective HSP length: 122
effective length of query: 3631
effective length of database: 13,627,866
effective search space: 49482781446
effective search space used: 49482781446
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 72 (32.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.