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Search of human proteins with 6631083
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|6631083 connexin 40 [Homo sapiens]
(358 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|32483412 connexin 40 [Homo sapiens] 743 0.0
gi|6631083 connexin 40 [Homo sapiens] 743 0.0
gi|55953076 connexin 50 [Homo sapiens] 312 3e-85
gi|22779877 connexin 46 [Homo sapiens] 307 1e-83
gi|62865885 connexin 37 [Homo sapiens] 276 3e-74
gi|31542845 gap junction protein, alpha 9, 59kDa [Homo sapiens] 276 3e-74
gi|14211941 gap junction protein, alpha 10 [Homo sapiens] 267 9e-72
gi|4504001 connexin 43 [Homo sapiens] 267 1e-71
gi|122939172 connexin 45 [Homo sapiens] 224 7e-59
gi|69122473 connexin 45 [Homo sapiens] 224 7e-59
gi|42558283 gap junction protein beta 2 [Homo sapiens] 202 5e-52
gi|10190698 gap junction protein, delta 2, 36kDa [Homo sapiens] 201 6e-52
gi|45439367 gap junction protein, gamma 2, 47kDa [Homo sapiens] 201 8e-52
gi|159032020 gap junction protein, beta 6 [Homo sapiens] 198 7e-51
gi|158966714 gap junction protein, beta 6 [Homo sapiens] 198 7e-51
gi|158966717 gap junction protein, beta 6 [Homo sapiens] 198 7e-51
gi|40254837 gap junction protein, beta 6 [Homo sapiens] 198 7e-51
gi|148233402 gap junction protein, beta 1, 32kDa [Homo sapiens] 190 1e-48
gi|4504005 gap junction protein, beta 1, 32kDa [Homo sapiens] 190 1e-48
gi|23397464 gap junction protein, beta 4 [Homo sapiens] 184 8e-47
gi|148839378 gap junction protein, delta 3, 31.9kDa [Homo sapiens] 182 3e-46
gi|10835079 gap junction protein, beta 5, 31.1kDa [Homo sapiens] 174 1e-43
gi|38348412 gap junction protein, beta 7, 25kDa [Homo sapiens] 164 1e-40
gi|54607056 connexin 31 [Homo sapiens] 161 7e-40
gi|13128960 connexin 31 [Homo sapiens] 161 7e-40
gi|145699105 connexin40.1 [Homo sapiens] 144 2e-34
gi|31559821 gap junction protein, gamma 3, 30.2kDa [Homo sapiens] 135 4e-32
gi|169171704 PREDICTED: similar to hCG1770601 [Homo sapiens] 87 2e-17
gi|169171845 PREDICTED: similar to hCG1770601 [Homo sapiens] 87 2e-17
gi|169171183 PREDICTED: similar to hCG1770601 [Homo sapiens] 87 2e-17
>gi|32483412 connexin 40 [Homo sapiens]
Length = 358
Score = 743 bits (1918), Expect = 0.0
Identities = 358/358 (100%), Positives = 358/358 (100%)
Query: 1 MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG 60
MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG
Sbjct: 1 MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG 60
Query: 61 CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGS 120
CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGS
Sbjct: 61 CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGS 120
Query: 121 GSYEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGIFLT 180
GSYEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGIFLT
Sbjct: 121 GSYEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGIFLT 180
Query: 181 TLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQRFVK 240
TLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQRFVK
Sbjct: 181 TLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQRFVK 240
Query: 241 PRQHMAKCQLSGPSVGIVQSCTPPPDFNQCLENGPGGKFFNPFSNNMASQQNTDNLVTEQ 300
PRQHMAKCQLSGPSVGIVQSCTPPPDFNQCLENGPGGKFFNPFSNNMASQQNTDNLVTEQ
Sbjct: 241 PRQHMAKCQLSGPSVGIVQSCTPPPDFNQCLENGPGGKFFNPFSNNMASQQNTDNLVTEQ 300
Query: 301 VRGQEQTPGEGFIQVRYGQKPEVPNGVSPGHRLPHGYHSDKRRLSKASSKARSDDLSV 358
VRGQEQTPGEGFIQVRYGQKPEVPNGVSPGHRLPHGYHSDKRRLSKASSKARSDDLSV
Sbjct: 301 VRGQEQTPGEGFIQVRYGQKPEVPNGVSPGHRLPHGYHSDKRRLSKASSKARSDDLSV 358
>gi|6631083 connexin 40 [Homo sapiens]
Length = 358
Score = 743 bits (1918), Expect = 0.0
Identities = 358/358 (100%), Positives = 358/358 (100%)
Query: 1 MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG 60
MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG
Sbjct: 1 MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG 60
Query: 61 CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGS 120
CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGS
Sbjct: 61 CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGS 120
Query: 121 GSYEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGIFLT 180
GSYEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGIFLT
Sbjct: 121 GSYEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGIFLT 180
Query: 181 TLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQRFVK 240
TLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQRFVK
Sbjct: 181 TLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQRFVK 240
Query: 241 PRQHMAKCQLSGPSVGIVQSCTPPPDFNQCLENGPGGKFFNPFSNNMASQQNTDNLVTEQ 300
PRQHMAKCQLSGPSVGIVQSCTPPPDFNQCLENGPGGKFFNPFSNNMASQQNTDNLVTEQ
Sbjct: 241 PRQHMAKCQLSGPSVGIVQSCTPPPDFNQCLENGPGGKFFNPFSNNMASQQNTDNLVTEQ 300
Query: 301 VRGQEQTPGEGFIQVRYGQKPEVPNGVSPGHRLPHGYHSDKRRLSKASSKARSDDLSV 358
VRGQEQTPGEGFIQVRYGQKPEVPNGVSPGHRLPHGYHSDKRRLSKASSKARSDDLSV
Sbjct: 301 VRGQEQTPGEGFIQVRYGQKPEVPNGVSPGHRLPHGYHSDKRRLSKASSKARSDDLSV 358
>gi|55953076 connexin 50 [Homo sapiens]
Length = 433
Score = 312 bits (800), Expect = 3e-85
Identities = 188/435 (43%), Positives = 243/435 (55%), Gaps = 79/435 (18%)
Query: 1 MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG 60
MGDWSFLGN LEEV++HSTV+G+VWLTVLFIFR+L+LGTAAE WGDEQ+DF C+T QPG
Sbjct: 1 MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPG 60
Query: 61 CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGS 120
C+NVCYD+AFPISHIR WVLQIIFVSTPSL+Y+GHA+H VRM+EKRK REAE + G+
Sbjct: 61 CENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEELGQQAGT 120
Query: 121 GSYEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGIFLT 180
P + S +G + L+GTLL TY+C I+ +T EVGFIVG YF+YG +
Sbjct: 121 NG--GPDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYGFRIL 178
Query: 181 TLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQRFVK 240
L+ C R PCP+ V+C+VSRPTEK +FI+FML+VA++SL L++ EL HLG K IR +
Sbjct: 179 PLYRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIRSALKR 238
Query: 241 P-------------------------------RQHMAKCQLSGPSVGIVQ-SCTPPPDFN 268
P + + VG+V+ S P FN
Sbjct: 239 PVEQPLGEIPEKSLHSIAVSSIQKAKGYQLLEEEKIVSHYFPLTEVGMVETSPLPAKPFN 298
Query: 269 QC---LENGPGGKFFNPFSNNMAS----------------QQNTDNLVTEQVRGQEQ--T 307
Q + GP G + + S ++ + V E+ E+ T
Sbjct: 299 QFEEKISTGPLGDLSRGYQETLPSYAQVGAQEVEGEGPPAEEGAEPEVGEKKEEAERLTT 358
Query: 308 PGEGFIQVRYGQKPEVPNGVSPGHR---------------------LPHGYHSDKR---R 343
+ + V G+K E P G + P D R R
Sbjct: 359 EEQEKVAVPEGEKVETPGVDKEGEKEEPQSEKVSKQGLPAEKTPSLCPELTTDDARPLSR 418
Query: 344 LSKASSKARSDDLSV 358
LSKASS+ARSDDL+V
Sbjct: 419 LSKASSRARSDDLTV 433
>gi|22779877 connexin 46 [Homo sapiens]
Length = 435
Score = 307 bits (786), Expect = 1e-83
Identities = 142/236 (60%), Positives = 177/236 (75%), Gaps = 4/236 (1%)
Query: 1 MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG 60
MGDWSFLG LE +HSTV+GKVWLTVLFIFR+LVLG AAE WGDEQ+DF C+T QPG
Sbjct: 1 MGDWSFLGRLLENAQEHSTVIGKVWLTVLFIFRILVLGAAAEDVWGDEQSDFTCNTQQPG 60
Query: 61 CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGS 120
C+NVCYD+AFPISHIR+W LQIIFVSTP+L+Y+GH +H VRM+EK+K RE E +
Sbjct: 61 CENVCYDRAFPISHIRFWALQIIFVSTPTLIYLGHVLHIVRMEEKKKEREEEEQLKRESP 120
Query: 121 GSYEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGIFLT 180
E P + + GR+ + G LL TYV +I+ +T EVGFI GQYF+YG L
Sbjct: 121 SPKEPPQDNPSS----RDDRGRVRMAGALLRTYVFNIIFKTLFEVGFIAGQYFLYGFELK 176
Query: 181 TLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQ 236
L+ C R PCP+ V+C++SRPTEK +FI+FMLAVA SLLL++ E+YHLGWKK++Q
Sbjct: 177 PLYRCDRWPCPNTVDCFISRPTEKTIFIIFMLAVACASLLLNMLEIYHLGWKKLKQ 232
>gi|62865885 connexin 37 [Homo sapiens]
Length = 333
Score = 276 bits (705), Expect = 3e-74
Identities = 147/325 (45%), Positives = 206/325 (63%), Gaps = 10/325 (3%)
Query: 1 MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG 60
MGDW FL L++V +HSTVVGK+WLTVLFIFR+L+LG A ES WGDEQ+DF C+T QPG
Sbjct: 1 MGDWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPG 60
Query: 61 CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAE----RAKE 116
C NVCYDQAFPISHIRYWVLQ +FVSTP+LVY+GH ++ R +E+ + +E E AK+
Sbjct: 61 CTNVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKD 120
Query: 117 VRGSGSYEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYG 176
+ + + A++S E+ GR+ ++G L+ TYV S+L ++ +E GF+ GQ+ +YG
Sbjct: 121 PQVERALAAVERQMAKISVAED--GRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLYG 178
Query: 177 IFLTTLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQ 236
+ + VC+R+PCP+ V+C+VSRPTEK +FI+FML V +SL+L+L EL HL + +
Sbjct: 179 WTMEPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCL-S 237
Query: 237 RFVKPRQHMAKCQLSGPSVGIVQSCTPPPDFNQCLENGPGGKFFNPFSNNMASQQNTDNL 296
R ++ RQ G S T F + GP ++ +S+QN NL
Sbjct: 238 RGMRARQGQDAPPTQGTS---SDPYTDQVFFYLPVGQGPSSPPCPTYNGLSSSEQNWANL 294
Query: 297 VTEQVRGQEQTPGEGFIQVRYGQKP 321
TE+ + P + GQKP
Sbjct: 295 TTEERLASSRPPLFLDPPPQNGQKP 319
>gi|31542845 gap junction protein, alpha 9, 59kDa [Homo sapiens]
Length = 515
Score = 276 bits (705), Expect = 3e-74
Identities = 143/314 (45%), Positives = 200/314 (63%), Gaps = 21/314 (6%)
Query: 1 MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG 60
MGDW+ LG+ LEEVH HST++GK+WLT+LFIFRMLVLG AAE W DEQ+ F C+T QPG
Sbjct: 1 MGDWNLLGDTLEEVHIHSTMIGKIWLTILFIFRMLVLGVAAEDVWNDEQSGFICNTEQPG 60
Query: 61 CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGS 120
C+NVCYDQAFPIS IRYWVLQ+IFVS+PSLVYMGHA++ +R+ E+ + R + +
Sbjct: 61 CRNVCYDQAFPISLIRYWVLQVIFVSSPSLVYMGHALYRLRVLEEERQRMKAQLRVELEE 120
Query: 121 GSYEYPVAEK---AELSCWEEGN-GRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYG 176
+E P + EL E+ + L+GTLL TYV I R+ +EVGF++GQY +YG
Sbjct: 121 VEFEMPRDRRRLEQELCQLEKRKLNKAPLRGTLLCTYVIHIFTRSVVEVGFMIGQYLLYG 180
Query: 177 IFLTTLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQ 236
L L C PCP+ ++C+VSRPTEK +F++FM ++A +SL L++ E++HLG+KKI++
Sbjct: 181 FHLEPLFKCHGHPCPNIIDCFVSRPTEKTIFLLFMQSIATISLFLNILEIFHLGFKKIKR 240
Query: 237 ---------------RFVKPRQHMAKCQLSGPSVGIVQSCTPPPDFNQCLENGPGGKFFN 281
K +Q++AK Q S ++ PD+N +E +
Sbjct: 241 GLWGKYKLKKEHNEFHANKAKQNVAKYQ--STSANSLKRLPSAPDYNLLVEKQTHTAVYP 298
Query: 282 PFSNNMASQQNTDN 295
+++ Q N DN
Sbjct: 299 SLNSSSVFQPNPDN 312
>gi|14211941 gap junction protein, alpha 10 [Homo sapiens]
Length = 543
Score = 267 bits (683), Expect = 9e-72
Identities = 132/244 (54%), Positives = 173/244 (70%), Gaps = 4/244 (1%)
Query: 1 MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG 60
MGDW+ LG LEEVH HST+VGK+WLT+LFIFRMLVL AAE W DEQ+ F C+T QPG
Sbjct: 1 MGDWNLLGGILEEVHSHSTIVGKIWLTILFIFRMLVLRVAAEDVWDDEQSAFACNTRQPG 60
Query: 61 CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAE--RAKEVR 118
C N+CYD AFPIS IR+WVLQIIFVS+PSLVYMGHA++ +R EK + R+ RA+
Sbjct: 61 CNNICYDDAFPISLIRFWVLQIIFVSSPSLVYMGHALYRLRAFEKDRQRKKSHLRAQMEN 120
Query: 119 GSGSYEYPVAEKAELSCWEEGN--GRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYG 176
E EL EE ++ L+G LL TYV IL R+ +EVGF++GQY +YG
Sbjct: 121 PDLDLEEQQRIDRELRRLEEQKRIHKVPLKGCLLRTYVLHILTRSVLEVGFMIGQYILYG 180
Query: 177 IFLTTLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQ 236
+ L+ C + PCP+ V+C+VSRPTEK +F++FM ++AA+SLLL++ E++HLG +KI +
Sbjct: 181 FQMHPLYKCTQPPCPNAVDCFVSRPTEKTIFMLFMHSIAAISLLLNILEIFHLGIRKIMR 240
Query: 237 RFVK 240
K
Sbjct: 241 TLYK 244
>gi|4504001 connexin 43 [Homo sapiens]
Length = 382
Score = 267 bits (682), Expect = 1e-71
Identities = 160/396 (40%), Positives = 233/396 (58%), Gaps = 52/396 (13%)
Query: 1 MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG 60
MGDWS LG L++V +ST GKVWL+VLFIFR+L+LGTA ES+WGDEQ+ FRC+T QPG
Sbjct: 1 MGDWSALGKLLDKVQAYSTAGGKVWLSVLFIFRILLLGTAVESAWGDEQSAFRCNTQQPG 60
Query: 61 CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGS 120
C+NVCYD++FPISH+R+WVLQIIFVS P+L+Y+ H + +R +EK +E E K +
Sbjct: 61 CENVCYDKSFPISHVRFWVLQIIFVSVPTLLYLAHVFYVMRKEEKLNKKE-EELKVAQTD 119
Query: 121 GSYEYPVAEKAELSCWEEG---NGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGI 177
G ++ E+ ++ G +G++ ++G LL TY+ SIL ++ EV F++ Q++IYG
Sbjct: 120 GVNVDMHLKQIEIKKFKYGIEEHGKVKMRGGLLRTYIISILFKSIFEVAFLLIQWYIYGF 179
Query: 178 FLTTLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQR 237
L+ ++ C+R PCPH V+C++SRPTEK +FI+FML V+ +SL L++ EL+++ +K ++ R
Sbjct: 180 SLSAVYTCKRDPCPHQVDCFLSRPTEKTIFIIFMLVVSLVSLALNIIELFYVFFKGVKDR 239
Query: 238 FVKPRQHMAKCQLSGPSVGIVQSCTPPPD--------FNQCLE--------NGPGGKFFN 281
VK + S P + +P D FN C + PG K
Sbjct: 240 -VKGK--------SDPYHATSGALSPAKDCGSQKYAYFNGCSSPTAPLSPMSPPGYKLVT 290
Query: 282 PFSNN--------MASQQNTDNLVTEQVR-GQEQTPGEGFIQVRYGQKPEVPNG------ 326
NN AS+QN N EQ R GQ + I + Q + P+
Sbjct: 291 GDRNNSSCRNYNKQASEQNWANYSAEQNRMGQAGST----ISNSHAQPFDFPDDNQNSKK 346
Query: 327 VSPGHRLPHGYHSDKRRLSKASSKA----RSDDLSV 358
++ GH L D+R S+ASS+A R DDL +
Sbjct: 347 LAAGHELQPLAIVDQRPSSRASSRASSRPRPDDLEI 382
>gi|122939172 connexin 45 [Homo sapiens]
Length = 396
Score = 224 bits (572), Expect = 7e-59
Identities = 135/385 (35%), Positives = 200/385 (51%), Gaps = 42/385 (10%)
Query: 4 WSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPGCQN 63
WSFL LEE+H HST VGK+WLTVL +FR+++ ES + DEQ+ F C+T QPGC+N
Sbjct: 3 WSFLTRLLEEIHNHSTFVGKIWLTVLIVFRIVLTAVGGESIYYDEQSKFVCNTEQPGCEN 62
Query: 64 VCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEK-----------------R 106
VCYD P+SH+R+WV QII V+TPS++Y+G+A+H + E +
Sbjct: 63 VCYDAFAPLSHVRFWVFQIILVATPSVMYLGYAIHKIAKMEHGEADKKAARSKPYAMRWK 122
Query: 107 KLREAERAKEVRGSGSYEYPV---------AEKAELSCWEEGNGRIALQGTLLNTYVCSI 157
+ R E +E YP E+++ +G RI G L+ YV +
Sbjct: 123 QHRALEETEEDNEEDPMMYPEMELESDKENKEQSQPKPKHDGRRRIREDG-LMKIYVLQL 181
Query: 158 LIRTTMEVGFIVGQYFIYGIFLTTLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAAL 217
L RT EVGF++GQYF+YG + +VC R PCPH ++C++SRPTEK +F++ M V L
Sbjct: 182 LARTVFEVGFLIGQYFLYGFQVHPFYVCSRLPCPHKIDCFISRPTEKTIFLLIMYGVTGL 241
Query: 218 SLLLSLAELYHLGWKKIRQRFVKPRQHMAKCQLSGPSV----GIVQSCTPPPDFNQCLEN 273
LLL++ E+ HLG+ IR R+ +L P + + PP +N ++
Sbjct: 242 CLLLNIWEMLHLGFGTIRDSLNSKRR-----ELEDPGAYNYPFTWNTPSAPPGYNIAVK- 295
Query: 274 GPGGKFFNPFSN-NMASQQNTDNLVTEQVRG--QEQTPGE-GFIQVRYGQKPEVPNGVSP 329
P + SN +A +QN N EQ G +E P + +Q E +
Sbjct: 296 -PDQIQYTELSNAKIAYKQNKANTAQEQQYGSHEENLPADLEALQREIRMAQERLDLAVQ 354
Query: 330 GHRLPHGYHSDKRRLSKASSKARSD 354
+ + H + + +K SKA S+
Sbjct: 355 AYSHQNNPHGPREKKAKVGSKAGSN 379
>gi|69122473 connexin 45 [Homo sapiens]
Length = 396
Score = 224 bits (572), Expect = 7e-59
Identities = 135/385 (35%), Positives = 200/385 (51%), Gaps = 42/385 (10%)
Query: 4 WSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPGCQN 63
WSFL LEE+H HST VGK+WLTVL +FR+++ ES + DEQ+ F C+T QPGC+N
Sbjct: 3 WSFLTRLLEEIHNHSTFVGKIWLTVLIVFRIVLTAVGGESIYYDEQSKFVCNTEQPGCEN 62
Query: 64 VCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEK-----------------R 106
VCYD P+SH+R+WV QII V+TPS++Y+G+A+H + E +
Sbjct: 63 VCYDAFAPLSHVRFWVFQIILVATPSVMYLGYAIHKIAKMEHGEADKKAARSKPYAMRWK 122
Query: 107 KLREAERAKEVRGSGSYEYPV---------AEKAELSCWEEGNGRIALQGTLLNTYVCSI 157
+ R E +E YP E+++ +G RI G L+ YV +
Sbjct: 123 QHRALEETEEDNEEDPMMYPEMELESDKENKEQSQPKPKHDGRRRIREDG-LMKIYVLQL 181
Query: 158 LIRTTMEVGFIVGQYFIYGIFLTTLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAAL 217
L RT EVGF++GQYF+YG + +VC R PCPH ++C++SRPTEK +F++ M V L
Sbjct: 182 LARTVFEVGFLIGQYFLYGFQVHPFYVCSRLPCPHKIDCFISRPTEKTIFLLIMYGVTGL 241
Query: 218 SLLLSLAELYHLGWKKIRQRFVKPRQHMAKCQLSGPSV----GIVQSCTPPPDFNQCLEN 273
LLL++ E+ HLG+ IR R+ +L P + + PP +N ++
Sbjct: 242 CLLLNIWEMLHLGFGTIRDSLNSKRR-----ELEDPGAYNYPFTWNTPSAPPGYNIAVK- 295
Query: 274 GPGGKFFNPFSN-NMASQQNTDNLVTEQVRG--QEQTPGE-GFIQVRYGQKPEVPNGVSP 329
P + SN +A +QN N EQ G +E P + +Q E +
Sbjct: 296 -PDQIQYTELSNAKIAYKQNKANTAQEQQYGSHEENLPADLEALQREIRMAQERLDLAVQ 354
Query: 330 GHRLPHGYHSDKRRLSKASSKARSD 354
+ + H + + +K SKA S+
Sbjct: 355 AYSHQNNPHGPREKKAKVGSKAGSN 379
>gi|42558283 gap junction protein beta 2 [Homo sapiens]
Length = 226
Score = 202 bits (513), Expect = 5e-52
Identities = 105/228 (46%), Positives = 144/228 (63%), Gaps = 17/228 (7%)
Query: 3 DWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPGCQ 62
DW L L V+KHST +GK+WLTVLFIFR+++L AA+ WGDEQADF C+T+QPGC+
Sbjct: 2 DWGTLQTILGGVNKHSTSIGKIWLTVLFIFRIMILVVAAKEVWGDEQADFVCNTLQPGCK 61
Query: 63 NVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGSGS 122
NVCYD FPISHIR W LQ+IFVSTP+L+ H + R EK++ K ++G
Sbjct: 62 NVCYDHYFPISHIRLWALQLIFVSTPALLVAMHVAY--RRHEKKR-------KFIKGEIK 112
Query: 123 YEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIY-GIFLTT 181
E+ E+ + ++ ++G+L TY SI R E F+ Y +Y G +
Sbjct: 113 SEFKDIEEIKTQ-------KVRIEGSLWWTYTSSIFFRVIFEAAFMYVFYVMYDGFSMQR 165
Query: 182 LHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHL 229
L C PCP+ V+C+VSRPTEK VF VFM+AV+ + +LL++ EL +L
Sbjct: 166 LVKCNAWPCPNTVDCFVSRPTEKTVFTVFMIAVSGICILLNVTELCYL 213
>gi|10190698 gap junction protein, delta 2, 36kDa [Homo sapiens]
Length = 321
Score = 201 bits (512), Expect = 6e-52
Identities = 107/281 (38%), Positives = 156/281 (55%), Gaps = 46/281 (16%)
Query: 1 MGDWSFLGNFLEE-VHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQP 59
MG+W+ L LE V +HST++G++ LTV+ IFR+L++ E+ + DEQ F C+T+QP
Sbjct: 1 MGEWTILERLLEAAVQQHSTMIGRILLTVVVIFRILIVAIVGETVYDDEQTMFVCNTLQP 60
Query: 60 GCQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKL----------- 108
GC CYD+AFPISHIRYWV QII V TPSL ++ +++H Q +R+
Sbjct: 61 GCNQACYDRAFPISHIRYWVFQIIMVCTPSLCFITYSVHQSAKQRERRYSTVFLALDRDP 120
Query: 109 -------------------REAERAKE--VRGSGSYEYPVAEKAELSCWE---------- 137
RE ++ + V G +++ E C E
Sbjct: 121 PESIGGPGGTGGGGSGGGKREDKKLQNAIVNGVLQNTENTSKETEPDCLEVKELTPHPSG 180
Query: 138 ---EGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGIFLTTLHVCRRSPCPHPV 194
++ Q + Y+ ++ R +E+GF+VGQYF+YG + L+ C R PC V
Sbjct: 181 LRTASKSKLRRQEGISRFYIIQVVFRNALEIGFLVGQYFLYGFSVPGLYECNRYPCIKEV 240
Query: 195 NCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIR 235
CYVSRPTEK VF+VFM AV+ + ++L+LAEL HLGW+KI+
Sbjct: 241 ECYVSRPTEKTVFLVFMFAVSGICVVLNLAELNHLGWRKIK 281
>gi|45439367 gap junction protein, gamma 2, 47kDa [Homo sapiens]
Length = 439
Score = 201 bits (511), Expect = 8e-52
Identities = 114/286 (39%), Positives = 155/286 (54%), Gaps = 60/286 (20%)
Query: 4 WSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPGCQN 63
WSFL LEE+H HST VGKVWLTVL +FR+++ E+ + DEQA F C+T QPGC N
Sbjct: 6 WSFLTRLLEEIHNHSTFVGKVWLTVLVVFRIVLTAVGGEAIYSDEQAKFTCNTRQPGCDN 65
Query: 64 VCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRM---QEKRKL-------REAER 113
VCYD P+SH+R+WV QI+ +STPS++Y+G+A+H + QE+R+ R A R
Sbjct: 66 VCYDAFAPLSHVRFWVFQIVVISTPSVMYLGYAVHRLARASEQERRRALRRRPGPRRAPR 125
Query: 114 A---------------------------KEVRGSGSYEYPVAEKAELSCWEEG------- 139
A +E +G+ E E+AE + EE
Sbjct: 126 AHLPPPHAGWPEPADLGEEEPMLGLGEEEEEEETGAAE-GAGEEAEEAGAEEACTKAVGA 184
Query: 140 --------------NGRIALQGT-LLNTYVCSILIRTTMEVGFIVGQYFIYGIFLTTLHV 184
+GR +Q L+ YV ++ R EV F+VGQY +YG +
Sbjct: 185 DGKAAGTPGPTGQHDGRRRIQREGLMRVYVAQLVARAAFEVAFLVGQYLLYGFEVRPFFP 244
Query: 185 CRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLG 230
C R PCPH V+C+VSRPTEK VF++ M V+ L LLL+L E+ HLG
Sbjct: 245 CSRQPCPHVVDCFVSRPTEKTVFLLVMYVVSCLCLLLNLCEMAHLG 290
>gi|159032020 gap junction protein, beta 6 [Homo sapiens]
Length = 261
Score = 198 bits (503), Expect = 7e-51
Identities = 98/228 (42%), Positives = 141/228 (61%), Gaps = 17/228 (7%)
Query: 3 DWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPGCQ 62
DW L F+ V+KHST +GKVW+TV+FIFR+++L AA+ WGDEQ DF C+T+QPGC+
Sbjct: 2 DWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGCK 61
Query: 63 NVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGSGS 122
NVCYD FP+SHIR W LQ+IFVSTP+L+ H + R + RK R E+ + +
Sbjct: 62 NVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAY-YRHETTRKFRRGEKRNDFKDIED 120
Query: 123 YEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIY-GIFLTT 181
+ ++ ++G+L TY SI R E F+ YF+Y G L
Sbjct: 121 IK---------------KQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPW 165
Query: 182 LHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHL 229
+ C PCP+ V+C++SRPTEK VF +FM++ + + +LL++AEL +L
Sbjct: 166 VLKCGIDPCPNLVDCFISRPTEKTVFTIFMISASVICMLLNVAELCYL 213
>gi|158966714 gap junction protein, beta 6 [Homo sapiens]
Length = 261
Score = 198 bits (503), Expect = 7e-51
Identities = 98/228 (42%), Positives = 141/228 (61%), Gaps = 17/228 (7%)
Query: 3 DWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPGCQ 62
DW L F+ V+KHST +GKVW+TV+FIFR+++L AA+ WGDEQ DF C+T+QPGC+
Sbjct: 2 DWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGCK 61
Query: 63 NVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGSGS 122
NVCYD FP+SHIR W LQ+IFVSTP+L+ H + R + RK R E+ + +
Sbjct: 62 NVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAY-YRHETTRKFRRGEKRNDFKDIED 120
Query: 123 YEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIY-GIFLTT 181
+ ++ ++G+L TY SI R E F+ YF+Y G L
Sbjct: 121 IK---------------KQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPW 165
Query: 182 LHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHL 229
+ C PCP+ V+C++SRPTEK VF +FM++ + + +LL++AEL +L
Sbjct: 166 VLKCGIDPCPNLVDCFISRPTEKTVFTIFMISASVICMLLNVAELCYL 213
>gi|158966717 gap junction protein, beta 6 [Homo sapiens]
Length = 261
Score = 198 bits (503), Expect = 7e-51
Identities = 98/228 (42%), Positives = 141/228 (61%), Gaps = 17/228 (7%)
Query: 3 DWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPGCQ 62
DW L F+ V+KHST +GKVW+TV+FIFR+++L AA+ WGDEQ DF C+T+QPGC+
Sbjct: 2 DWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGCK 61
Query: 63 NVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGSGS 122
NVCYD FP+SHIR W LQ+IFVSTP+L+ H + R + RK R E+ + +
Sbjct: 62 NVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAY-YRHETTRKFRRGEKRNDFKDIED 120
Query: 123 YEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIY-GIFLTT 181
+ ++ ++G+L TY SI R E F+ YF+Y G L
Sbjct: 121 IK---------------KQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPW 165
Query: 182 LHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHL 229
+ C PCP+ V+C++SRPTEK VF +FM++ + + +LL++AEL +L
Sbjct: 166 VLKCGIDPCPNLVDCFISRPTEKTVFTIFMISASVICMLLNVAELCYL 213
>gi|40254837 gap junction protein, beta 6 [Homo sapiens]
Length = 261
Score = 198 bits (503), Expect = 7e-51
Identities = 98/228 (42%), Positives = 141/228 (61%), Gaps = 17/228 (7%)
Query: 3 DWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPGCQ 62
DW L F+ V+KHST +GKVW+TV+FIFR+++L AA+ WGDEQ DF C+T+QPGC+
Sbjct: 2 DWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGCK 61
Query: 63 NVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGSGS 122
NVCYD FP+SHIR W LQ+IFVSTP+L+ H + R + RK R E+ + +
Sbjct: 62 NVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAY-YRHETTRKFRRGEKRNDFKDIED 120
Query: 123 YEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIY-GIFLTT 181
+ ++ ++G+L TY SI R E F+ YF+Y G L
Sbjct: 121 IK---------------KQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPW 165
Query: 182 LHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHL 229
+ C PCP+ V+C++SRPTEK VF +FM++ + + +LL++AEL +L
Sbjct: 166 VLKCGIDPCPNLVDCFISRPTEKTVFTIFMISASVICMLLNVAELCYL 213
>gi|148233402 gap junction protein, beta 1, 32kDa [Homo sapiens]
Length = 283
Score = 190 bits (483), Expect = 1e-48
Identities = 101/228 (44%), Positives = 142/228 (62%), Gaps = 18/228 (7%)
Query: 3 DWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPGCQ 62
+W+ L L V++HST +G+VWL+V+FIFR++VL AAES WGDE++ F C+T+QPGC
Sbjct: 2 NWTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGCN 61
Query: 63 NVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGSGS 122
+VCYDQ FPISH+R W LQ+I VSTP+L+ H H + EK+ LR + G G
Sbjct: 62 SVCYDQFFPISHVRLWSLQLILVSTPALLVAMHVAHQQHI-EKKMLR-------LEGHGD 113
Query: 123 YEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIY-GIFLTT 181
L E ++ + GTL TYV S++ R E F+ Y +Y G +
Sbjct: 114 ---------PLHLEEVKRHKVHISGTLWWTYVISVVFRLLFEAVFMYVFYLLYPGYAMVR 164
Query: 182 LHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHL 229
L C PCP+ V+C+VSRPTEK VF VFMLA + + ++L++AE+ +L
Sbjct: 165 LVKCDVYPCPNTVDCFVSRPTEKTVFTVFMLAASGICIILNVAEVVYL 212
>gi|4504005 gap junction protein, beta 1, 32kDa [Homo sapiens]
Length = 283
Score = 190 bits (483), Expect = 1e-48
Identities = 101/228 (44%), Positives = 142/228 (62%), Gaps = 18/228 (7%)
Query: 3 DWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPGCQ 62
+W+ L L V++HST +G+VWL+V+FIFR++VL AAES WGDE++ F C+T+QPGC
Sbjct: 2 NWTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGCN 61
Query: 63 NVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGSGS 122
+VCYDQ FPISH+R W LQ+I VSTP+L+ H H + EK+ LR + G G
Sbjct: 62 SVCYDQFFPISHVRLWSLQLILVSTPALLVAMHVAHQQHI-EKKMLR-------LEGHGD 113
Query: 123 YEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIY-GIFLTT 181
L E ++ + GTL TYV S++ R E F+ Y +Y G +
Sbjct: 114 ---------PLHLEEVKRHKVHISGTLWWTYVISVVFRLLFEAVFMYVFYLLYPGYAMVR 164
Query: 182 LHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHL 229
L C PCP+ V+C+VSRPTEK VF VFMLA + + ++L++AE+ +L
Sbjct: 165 LVKCDVYPCPNTVDCFVSRPTEKTVFTVFMLAASGICIILNVAEVVYL 212
>gi|23397464 gap junction protein, beta 4 [Homo sapiens]
Length = 266
Score = 184 bits (468), Expect = 8e-47
Identities = 94/248 (37%), Positives = 145/248 (58%), Gaps = 23/248 (9%)
Query: 3 DWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPGCQ 62
+W+FL L V+K+STV+ ++WL+V+FIFR+LV AAE W DEQ DF C+T QPGC
Sbjct: 2 NWAFLQGLLSGVNKYSTVLSRIWLSVVFIFRVLVYVVAAEEVWDDEQKDFVCNTKQPGCP 61
Query: 63 NVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGSGS 122
NVCYD+ FP+SH+R W LQ+I V+ PSL+ + H + + K L+ A + + S
Sbjct: 62 NVCYDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYREERERKHHLKHGPNAPSLYDNLS 121
Query: 123 YEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGIF-LTT 181
+ +G L TY+ S++ + ++ GF+ + +Y + +
Sbjct: 122 KK---------------------RGGLWWTYLLSLIFKAAVDAGFLYIFHRLYKDYDMPR 160
Query: 182 LHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQRFVKP 241
+ C PCPH V+CY+SRPTEK VF FM+ AA+ +LL+L+E+++L K+ + F P
Sbjct: 161 VVACSVEPCPHTVDCYISRPTEKKVFTYFMVTTAAICILLNLSEVFYLVGKRCMEIF-GP 219
Query: 242 RQHMAKCQ 249
R +C+
Sbjct: 220 RHRRPRCR 227
>gi|148839378 gap junction protein, delta 3, 31.9kDa [Homo sapiens]
Length = 294
Score = 182 bits (463), Expect = 3e-46
Identities = 93/233 (39%), Positives = 135/233 (57%), Gaps = 19/233 (8%)
Query: 1 MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG 60
MG+W+FLG+ L+ V S +VG++WL V+ IFR+LVL T + + DEQ +F C+T+QPG
Sbjct: 1 MGEWAFLGSLLDAVQLQSPLVGRLWLVVMLIFRILVLATVGGAVFEDEQEEFVCNTLQPG 60
Query: 61 CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGS 120
C+ CYD+AFP+SH R+W+ I+ +S P ++++ ++MH KE G+
Sbjct: 61 CRQTCYDRAFPVSHYRFWLFHILLLSAPPVLFVVYSMH-------------RAGKEAGGA 107
Query: 121 GSYEYPVAEKAELSCWEEGNGRIALQG-TLLNTYVCSILIRTTMEVGFIVGQYFIYGIFL 179
+ E C AL+ Y+ S+ +R E+ F+ GQ +YG +
Sbjct: 108 EAAAQCAPGLPEAQC-----APCALRARRARRCYLLSVALRLLAELTFLGGQALLYGFRV 162
Query: 180 TTLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWK 232
C PCPH V+C+VSRPTEK VF++F AV LS LLS+AEL HL WK
Sbjct: 163 APHFACAGPPCPHTVDCFVSRPTEKTVFVLFYFAVGLLSALLSVAELGHLLWK 215
>gi|10835079 gap junction protein, beta 5, 31.1kDa [Homo sapiens]
Length = 273
Score = 174 bits (441), Expect = 1e-43
Identities = 98/265 (36%), Positives = 149/265 (56%), Gaps = 34/265 (12%)
Query: 3 DWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPGCQ 62
+WS L V+K+ST G++WL+++FIFR+LV AE W D+ DF C+T QPGC
Sbjct: 2 NWSIFEGLLSGVNKYSTAFGRIWLSLVFIFRVLVYLVTAERVWSDDHKDFDCNTRQPGCS 61
Query: 63 NVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGSGS 122
NVC+D+ FP+SH+R W LQ+I V+ PSL+ + H + +QEKR +E G
Sbjct: 62 NVCFDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYR-EVQEKRH-------REAHG--- 110
Query: 123 YEYPVAEKAELSCWEEGNGRIAL-----QGTLLNTYVCSILIRTTMEVGFI-VGQYFIYG 176
E +GR+ L +G L TYVCS++ + ++++ F+ V F
Sbjct: 111 ---------------ENSGRLYLNPGKKRGGLWWTYVCSLVFKASVDIAFLYVFHSFYPK 155
Query: 177 IFLTTLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQ 236
L + C PCP+ V+C++S+P+EKN+F +FM+A AA+ +LL+L EL +L K+ +
Sbjct: 156 YILPPVVKCHADPCPNIVDCFISKPSEKNIFTLFMVATAAICILLNLVELIYLVSKRCHE 215
Query: 237 RFVKPRQHMAKCQLSGPSVGIVQSC 261
+ R+ A C P G SC
Sbjct: 216 -CLAARKAQAMCTGHHPH-GTTSSC 238
>gi|38348412 gap junction protein, beta 7, 25kDa [Homo sapiens]
Length = 223
Score = 164 bits (415), Expect = 1e-40
Identities = 87/227 (38%), Positives = 130/227 (57%), Gaps = 29/227 (12%)
Query: 4 WSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPGCQN 63
W FL + L V+K+ST G +WL V+F+FR+LV AAE W DEQ +F C++ QPGC+N
Sbjct: 3 WMFLRDLLSGVNKYSTGTGWIWLAVVFVFRLLVYMVAAEHVWKDEQKEFECNSRQPGCKN 62
Query: 64 VCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGSGSY 123
VC+D FPIS +R W LQ+I VSTPSL+ + H V E R+ R ++ G+
Sbjct: 63 VCFDDFFPISQVRLWALQLIMVSTPSLLVVLH----VAYHEGREKRHRKKLYVSPGT--- 115
Query: 124 EYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIY-GIFLTTL 182
+ G L Y+ S++++T E+GF+V Y +Y G + L
Sbjct: 116 ---------------------MDGGLWYAYLISLIVKTGFEIGFLVLFYKLYDGFSVPYL 154
Query: 183 HVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHL 229
C PCP+ V+C++S+PTEK +FI+F++ + L ++L+ EL L
Sbjct: 155 IKCDLKPCPNTVDCFISKPTEKTIFILFLVITSCLCIVLNFIELSFL 201
>gi|54607056 connexin 31 [Homo sapiens]
Length = 270
Score = 161 bits (408), Expect = 7e-40
Identities = 83/229 (36%), Positives = 133/229 (58%), Gaps = 23/229 (10%)
Query: 3 DWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPGCQ 62
DW L L V+K+ST G++WL+V+F+FR+LV AAE WGDEQ DF C+T QPGC
Sbjct: 2 DWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGCT 61
Query: 63 NVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGSGS 122
NVCYD FPIS+IR W LQ+IFV+ PSL+ + H + + + + + ++ ++ +
Sbjct: 62 NVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYREERERRHRQKHGDQCAKLYDNAG 121
Query: 123 YEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFI-YGIFLTT 181
++ G L TY+ S++ + +E F+ + + +G +
Sbjct: 122 KKH---------------------GGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPR 160
Query: 182 LHVCRR-SPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHL 229
L C +PCP+ V+CY++RPTEK +F FM+ +A+ ++L++ EL +L
Sbjct: 161 LVQCANVAPCPNIVDCYIARPTEKKIFTYFMVGASAVCIVLTICELCYL 209
>gi|13128960 connexin 31 [Homo sapiens]
Length = 270
Score = 161 bits (408), Expect = 7e-40
Identities = 83/229 (36%), Positives = 133/229 (58%), Gaps = 23/229 (10%)
Query: 3 DWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPGCQ 62
DW L L V+K+ST G++WL+V+F+FR+LV AAE WGDEQ DF C+T QPGC
Sbjct: 2 DWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGCT 61
Query: 63 NVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGSGS 122
NVCYD FPIS+IR W LQ+IFV+ PSL+ + H + + + + + ++ ++ +
Sbjct: 62 NVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYREERERRHRQKHGDQCAKLYDNAG 121
Query: 123 YEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFI-YGIFLTT 181
++ G L TY+ S++ + +E F+ + + +G +
Sbjct: 122 KKH---------------------GGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPR 160
Query: 182 LHVCRR-SPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHL 229
L C +PCP+ V+CY++RPTEK +F FM+ +A+ ++L++ EL +L
Sbjct: 161 LVQCANVAPCPNIVDCYIARPTEKKIFTYFMVGASAVCIVLTICELCYL 209
>gi|145699105 connexin40.1 [Homo sapiens]
Length = 370
Score = 144 bits (362), Expect = 2e-34
Identities = 81/232 (34%), Positives = 123/232 (53%), Gaps = 12/232 (5%)
Query: 7 LGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPGCQNVCY 66
LG + ++ + T+VGK+W + + RMLV+ A + DEQ F C+T+QPGC NVCY
Sbjct: 7 LGFLIITLNCNVTMVGKLWFVLTMLLRMLVIVLAGRPVYQDEQERFVCNTLQPGCANVCY 66
Query: 67 DQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKE-VRGSGSYEY 125
D P+SH+R+W++Q + V PS V+ + +H R +E G
Sbjct: 67 DVFSPVSHLRFWLIQGVCVLLPSAVFSVYVLHRGATLAALGPRRCPDPREPASGQRRCPR 126
Query: 126 PVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGIFLTTLHVC 185
P E+ L + G Y+ +L+RT +E F YF++G C
Sbjct: 127 PFGERGGLQVPDFSAG-----------YIIHLLLRTLLEAAFGALHYFLFGFLAPKKFPC 175
Query: 186 RRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQR 237
R PC V+CYVSRPTEK++ ++F+ AV+ALS LL LA+L +++R+R
Sbjct: 176 TRPPCTGVVDCYVSRPTEKSLLMLFLWAVSALSFLLGLADLVCSLRRRMRRR 227
>gi|31559821 gap junction protein, gamma 3, 30.2kDa [Homo sapiens]
Length = 279
Score = 135 bits (341), Expect = 4e-32
Identities = 78/225 (34%), Positives = 116/225 (51%), Gaps = 15/225 (6%)
Query: 6 FLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPGCQNVC 65
FL L E + ST VG++ L VL FR+++L + +GDEQ++F C T QPGC+ C
Sbjct: 5 FLRRLLAEESRRSTPVGRLLLPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAAC 64
Query: 66 YDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGSGSYEY 125
+D P+S +R+WV Q+I V+ PS +YMG ++ V E+ G G E
Sbjct: 65 FDAFHPLSPLRFWVFQVILVAVPSALYMGFTLYHVIWH-----------WELSGKGKEEE 113
Query: 126 PVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGIFLTTLHVC 185
+ + E + G G + LL YV + R +E + QY +YG + + C
Sbjct: 114 TLIQGREGNTDVPGAGSL----RLLWAYVAQLGARLVLEGAALGLQYHLYGFQMPSSFAC 169
Query: 186 RRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLG 230
RR PC + C +SRP+EK +F+ M V+ LL + EL LG
Sbjct: 170 RREPCLGSITCNLSRPSEKTIFLKTMFGVSGFCLLFTFLELVLLG 214
>gi|169171704 PREDICTED: similar to hCG1770601 [Homo sapiens]
Length = 222
Score = 87.0 bits (214), Expect = 2e-17
Identities = 38/85 (44%), Positives = 57/85 (67%)
Query: 11 LEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPGCQNVCYDQAF 70
L E HST VG++ VL FR+++L + +GDEQ++F C T QPGC+ C+D
Sbjct: 29 LAEESWHSTPVGRLLFPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACFDAFH 88
Query: 71 PISHIRYWVLQIIFVSTPSLVYMGH 95
P+S +R+WV Q+I V+ PS++YMG+
Sbjct: 89 PLSPLRFWVFQVILVAVPSVLYMGY 113
>gi|169171845 PREDICTED: similar to hCG1770601 [Homo sapiens]
Length = 222
Score = 87.0 bits (214), Expect = 2e-17
Identities = 38/85 (44%), Positives = 57/85 (67%)
Query: 11 LEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPGCQNVCYDQAF 70
L E HST VG++ VL FR+++L + +GDEQ++F C T QPGC+ C+D
Sbjct: 29 LAEESWHSTPVGRLLFPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACFDAFH 88
Query: 71 PISHIRYWVLQIIFVSTPSLVYMGH 95
P+S +R+WV Q+I V+ PS++YMG+
Sbjct: 89 PLSPLRFWVFQVILVAVPSVLYMGY 113
>gi|169171183 PREDICTED: similar to hCG1770601 [Homo sapiens]
Length = 222
Score = 87.0 bits (214), Expect = 2e-17
Identities = 38/85 (44%), Positives = 57/85 (67%)
Query: 11 LEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPGCQNVCYDQAF 70
L E HST VG++ VL FR+++L + +GDEQ++F C T QPGC+ C+D
Sbjct: 29 LAEESWHSTPVGRLLFPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACFDAFH 88
Query: 71 PISHIRYWVLQIIFVSTPSLVYMGH 95
P+S +R+WV Q+I V+ PS++YMG+
Sbjct: 89 PLSPLRFWVFQVILVAVPSVLYMGY 113
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.137 0.431
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,366,738
Number of Sequences: 37866
Number of extensions: 720685
Number of successful extensions: 1677
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 32
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 1604
Number of HSP's gapped (non-prelim): 50
length of query: 358
length of database: 18,247,518
effective HSP length: 103
effective length of query: 255
effective length of database: 14,347,320
effective search space: 3658566600
effective search space used: 3658566600
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.