Search of human proteins with 6466466

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|6466466 RAN binding protein 3 isoform RANBP3-d [Homo
sapiens]
         (567 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|6466466 RAN binding protein 3 isoform RANBP3-d [Homo sapiens]     1121   0.0  
gi|194097487 RAN binding protein 3 isoform RANBP3-a [Homo sapiens]   1105   0.0  
gi|194097489 RAN binding protein 3 isoform RANBP3-b [Homo sapiens]    927   0.0  
gi|239582743 RAN binding protein 3-like isoform 2 [Homo sapiens]      235   7e-62
gi|239582745 RAN binding protein 3-like isoform 1 [Homo sapiens]      233   5e-61
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap...    57   6e-08
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        54   5e-07
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa...    51   2e-06
gi|24308394 hypothetical protein LOC140893 [Homo sapiens]              50   4e-06
gi|169162953 PREDICTED: RANBP2-like and GRIP domain containing 8...    50   7e-06
gi|83267877 RANBP2-like and GRIP domain containing 5 isoform 1 [...    50   7e-06
gi|182765478 RANBP2-like and GRIP domain containing 6 [Homo sapi...    50   7e-06
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre...    50   7e-06
gi|150418007 RAN binding protein 2 [Homo sapiens]                      49   1e-05
gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]       49   2e-05
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     48   2e-05
gi|153070260 myristoylated alanine-rich protein kinase C substra...    48   3e-05
gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithora...    47   4e-05
gi|163965366 nascent polypeptide-associated complex alpha subuni...    47   4e-05
gi|149773456 hypothetical protein LOC643314 [Homo sapiens]             47   5e-05
gi|115648142 centrosomal protein 164kDa [Homo sapiens]                 47   5e-05
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     47   5e-05
gi|91208418 transcription elongation regulator 1 isoform 2 [Homo...    47   5e-05
gi|21327715 transcription elongation regulator 1 isoform 1 [Homo...    47   5e-05
gi|221307607 RANBP2-like and GRIP domain containing 3 [Homo sapi...    47   6e-05
gi|239747210 PREDICTED: hypothetical protein XP_002346689 [Homo ...    47   6e-05
gi|157266273 RANBP2-like and GRIP domain containing 1 [Homo sapi...    47   6e-05
gi|118200331 RANBP2-like and GRIP domain containing 2 [Homo sapi...    47   6e-05
gi|211059431 RANBP2-like and GRIP domain containing 4 [Homo sapi...    46   8e-05
gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Ho...    46   8e-05

>gi|6466466 RAN binding protein 3 isoform RANBP3-d [Homo sapiens]
          Length = 567

 Score = 1121 bits (2899), Expect = 0.0
 Identities = 567/567 (100%), Positives = 567/567 (100%)

Query: 1   MADLANEEKPAIAPPVFVFQKDKGQKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGE 60
           MADLANEEKPAIAPPVFVFQKDKGQKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGE
Sbjct: 1   MADLANEEKPAIAPPVFVFQKDKGQKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGE 60

Query: 61  HALEPPAPAGASASTPPPPAPEAQLPPFPRELAGRSAGGSSPEGGEDSDREDGNYCPPVK 120
           HALEPPAPAGASASTPPPPAPEAQLPPFPRELAGRSAGGSSPEGGEDSDREDGNYCPPVK
Sbjct: 61  HALEPPAPAGASASTPPPPAPEAQLPPFPRELAGRSAGGSSPEGGEDSDREDGNYCPPVK 120

Query: 121 RERTSSLTQFPPSQSEERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRPAVLQAP 180
           RERTSSLTQFPPSQSEERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRPAVLQAP
Sbjct: 121 RERTSSLTQFPPSQSEERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRPAVLQAP 180

Query: 181 QPKALSQTVPSSGTNGVSLPADCTGAVPAASPDTAAWRSPSEAADEVCALEEKEPQKNES 240
           QPKALSQTVPSSGTNGVSLPADCTGAVPAASPDTAAWRSPSEAADEVCALEEKEPQKNES
Sbjct: 181 QPKALSQTVPSSGTNGVSLPADCTGAVPAASPDTAAWRSPSEAADEVCALEEKEPQKNES 240

Query: 241 SNASEEEACEKKDPATQQAFVFGQNLRDRVKLINESVDEADMENAGHPSADTPTATNYFL 300
           SNASEEEACEKKDPATQQAFVFGQNLRDRVKLINESVDEADMENAGHPSADTPTATNYFL
Sbjct: 241 SNASEEEACEKKDPATQQAFVFGQNLRDRVKLINESVDEADMENAGHPSADTPTATNYFL 300

Query: 301 QYISSSLENSTNSADASSNKFVFGQNMSERVLSPPKLNEVSSDANRENAAAESGSESSSQ 360
           QYISSSLENSTNSADASSNKFVFGQNMSERVLSPPKLNEVSSDANRENAAAESGSESSSQ
Sbjct: 301 QYISSSLENSTNSADASSNKFVFGQNMSERVLSPPKLNEVSSDANRENAAAESGSESSSQ 360

Query: 361 EATPEKESLAESAAAYTKATARKCLLEKVEVITGEEAESNVLQMQCKLFVFDKTSQSWVE 420
           EATPEKESLAESAAAYTKATARKCLLEKVEVITGEEAESNVLQMQCKLFVFDKTSQSWVE
Sbjct: 361 EATPEKESLAESAAAYTKATARKCLLEKVEVITGEEAESNVLQMQCKLFVFDKTSQSWVE 420

Query: 421 RGRGLLRLNDMASTDDGTLQSRLVMRTQGSLRLILNTKLWAQMQIDKASEKSIRITAMDT 480
           RGRGLLRLNDMASTDDGTLQSRLVMRTQGSLRLILNTKLWAQMQIDKASEKSIRITAMDT
Sbjct: 421 RGRGLLRLNDMASTDDGTLQSRLVMRTQGSLRLILNTKLWAQMQIDKASEKSIRITAMDT 480

Query: 481 EDQGVKVFLISASSKDTGQLYAALHHRILALRSRVEQEQEAKMPAPEPGAAPSNEEDDSD 540
           EDQGVKVFLISASSKDTGQLYAALHHRILALRSRVEQEQEAKMPAPEPGAAPSNEEDDSD
Sbjct: 481 EDQGVKVFLISASSKDTGQLYAALHHRILALRSRVEQEQEAKMPAPEPGAAPSNEEDDSD 540

Query: 541 DDDVLAPSGATAAGAGDEGDGQTTGST 567
           DDDVLAPSGATAAGAGDEGDGQTTGST
Sbjct: 541 DDDVLAPSGATAAGAGDEGDGQTTGST 567


>gi|194097487 RAN binding protein 3 isoform RANBP3-a [Homo sapiens]
          Length = 562

 Score = 1105 bits (2857), Expect = 0.0
 Identities = 562/567 (99%), Positives = 562/567 (99%), Gaps = 5/567 (0%)

Query: 1   MADLANEEKPAIAPPVFVFQKDKGQKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGE 60
           MADLANEEKPAIAPPVFVFQKDKGQKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGE
Sbjct: 1   MADLANEEKPAIAPPVFVFQKDKGQKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGE 60

Query: 61  HALEPPAPAGASASTPPPPAPEAQLPPFPRELAGRSAGGSSPEGGEDSDREDGNYCPPVK 120
           HALEPPAPAGASASTPPPPAPEAQLPPFPRELAGRSAGGSSPEGGEDSDREDGNYCPPVK
Sbjct: 61  HALEPPAPAGASASTPPPPAPEAQLPPFPRELAGRSAGGSSPEGGEDSDREDGNYCPPVK 120

Query: 121 RERTSSLTQFPPSQSEERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRPAVLQAP 180
           RERTSSLTQFPPSQSEERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRPAVLQAP
Sbjct: 121 RERTSSLTQFPPSQSEERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRPAVLQAP 180

Query: 181 QPKALSQTVPSSGTNGVSLPADCTGAVPAASPDTAAWRSPSEAADEVCALEEKEPQKNES 240
           QPKALSQTVPSSGTNGVSLPADCTGAVPAASPDTAAWRSPSEAADE     EKEPQKNES
Sbjct: 181 QPKALSQTVPSSGTNGVSLPADCTGAVPAASPDTAAWRSPSEAADE-----EKEPQKNES 235

Query: 241 SNASEEEACEKKDPATQQAFVFGQNLRDRVKLINESVDEADMENAGHPSADTPTATNYFL 300
           SNASEEEACEKKDPATQQAFVFGQNLRDRVKLINESVDEADMENAGHPSADTPTATNYFL
Sbjct: 236 SNASEEEACEKKDPATQQAFVFGQNLRDRVKLINESVDEADMENAGHPSADTPTATNYFL 295

Query: 301 QYISSSLENSTNSADASSNKFVFGQNMSERVLSPPKLNEVSSDANRENAAAESGSESSSQ 360
           QYISSSLENSTNSADASSNKFVFGQNMSERVLSPPKLNEVSSDANRENAAAESGSESSSQ
Sbjct: 296 QYISSSLENSTNSADASSNKFVFGQNMSERVLSPPKLNEVSSDANRENAAAESGSESSSQ 355

Query: 361 EATPEKESLAESAAAYTKATARKCLLEKVEVITGEEAESNVLQMQCKLFVFDKTSQSWVE 420
           EATPEKESLAESAAAYTKATARKCLLEKVEVITGEEAESNVLQMQCKLFVFDKTSQSWVE
Sbjct: 356 EATPEKESLAESAAAYTKATARKCLLEKVEVITGEEAESNVLQMQCKLFVFDKTSQSWVE 415

Query: 421 RGRGLLRLNDMASTDDGTLQSRLVMRTQGSLRLILNTKLWAQMQIDKASEKSIRITAMDT 480
           RGRGLLRLNDMASTDDGTLQSRLVMRTQGSLRLILNTKLWAQMQIDKASEKSIRITAMDT
Sbjct: 416 RGRGLLRLNDMASTDDGTLQSRLVMRTQGSLRLILNTKLWAQMQIDKASEKSIRITAMDT 475

Query: 481 EDQGVKVFLISASSKDTGQLYAALHHRILALRSRVEQEQEAKMPAPEPGAAPSNEEDDSD 540
           EDQGVKVFLISASSKDTGQLYAALHHRILALRSRVEQEQEAKMPAPEPGAAPSNEEDDSD
Sbjct: 476 EDQGVKVFLISASSKDTGQLYAALHHRILALRSRVEQEQEAKMPAPEPGAAPSNEEDDSD 535

Query: 541 DDDVLAPSGATAAGAGDEGDGQTTGST 567
           DDDVLAPSGATAAGAGDEGDGQTTGST
Sbjct: 536 DDDVLAPSGATAAGAGDEGDGQTTGST 562


>gi|194097489 RAN binding protein 3 isoform RANBP3-b [Homo sapiens]
          Length = 499

 Score =  927 bits (2395), Expect = 0.0
 Identities = 473/473 (100%), Positives = 473/473 (100%)

Query: 95  RSAGGSSPEGGEDSDREDGNYCPPVKRERTSSLTQFPPSQSEERSSGFRLKPPTLIHGQA 154
           RSAGGSSPEGGEDSDREDGNYCPPVKRERTSSLTQFPPSQSEERSSGFRLKPPTLIHGQA
Sbjct: 27  RSAGGSSPEGGEDSDREDGNYCPPVKRERTSSLTQFPPSQSEERSSGFRLKPPTLIHGQA 86

Query: 155 PSAGLPSQKPKEQQRSVLRPAVLQAPQPKALSQTVPSSGTNGVSLPADCTGAVPAASPDT 214
           PSAGLPSQKPKEQQRSVLRPAVLQAPQPKALSQTVPSSGTNGVSLPADCTGAVPAASPDT
Sbjct: 87  PSAGLPSQKPKEQQRSVLRPAVLQAPQPKALSQTVPSSGTNGVSLPADCTGAVPAASPDT 146

Query: 215 AAWRSPSEAADEVCALEEKEPQKNESSNASEEEACEKKDPATQQAFVFGQNLRDRVKLIN 274
           AAWRSPSEAADEVCALEEKEPQKNESSNASEEEACEKKDPATQQAFVFGQNLRDRVKLIN
Sbjct: 147 AAWRSPSEAADEVCALEEKEPQKNESSNASEEEACEKKDPATQQAFVFGQNLRDRVKLIN 206

Query: 275 ESVDEADMENAGHPSADTPTATNYFLQYISSSLENSTNSADASSNKFVFGQNMSERVLSP 334
           ESVDEADMENAGHPSADTPTATNYFLQYISSSLENSTNSADASSNKFVFGQNMSERVLSP
Sbjct: 207 ESVDEADMENAGHPSADTPTATNYFLQYISSSLENSTNSADASSNKFVFGQNMSERVLSP 266

Query: 335 PKLNEVSSDANRENAAAESGSESSSQEATPEKESLAESAAAYTKATARKCLLEKVEVITG 394
           PKLNEVSSDANRENAAAESGSESSSQEATPEKESLAESAAAYTKATARKCLLEKVEVITG
Sbjct: 267 PKLNEVSSDANRENAAAESGSESSSQEATPEKESLAESAAAYTKATARKCLLEKVEVITG 326

Query: 395 EEAESNVLQMQCKLFVFDKTSQSWVERGRGLLRLNDMASTDDGTLQSRLVMRTQGSLRLI 454
           EEAESNVLQMQCKLFVFDKTSQSWVERGRGLLRLNDMASTDDGTLQSRLVMRTQGSLRLI
Sbjct: 327 EEAESNVLQMQCKLFVFDKTSQSWVERGRGLLRLNDMASTDDGTLQSRLVMRTQGSLRLI 386

Query: 455 LNTKLWAQMQIDKASEKSIRITAMDTEDQGVKVFLISASSKDTGQLYAALHHRILALRSR 514
           LNTKLWAQMQIDKASEKSIRITAMDTEDQGVKVFLISASSKDTGQLYAALHHRILALRSR
Sbjct: 387 LNTKLWAQMQIDKASEKSIRITAMDTEDQGVKVFLISASSKDTGQLYAALHHRILALRSR 446

Query: 515 VEQEQEAKMPAPEPGAAPSNEEDDSDDDDVLAPSGATAAGAGDEGDGQTTGST 567
           VEQEQEAKMPAPEPGAAPSNEEDDSDDDDVLAPSGATAAGAGDEGDGQTTGST
Sbjct: 447 VEQEQEAKMPAPEPGAAPSNEEDDSDDDDVLAPSGATAAGAGDEGDGQTTGST 499


>gi|239582743 RAN binding protein 3-like isoform 2 [Homo sapiens]
          Length = 465

 Score =  235 bits (600), Expect = 7e-62
 Identities = 163/439 (37%), Positives = 228/439 (51%), Gaps = 74/439 (16%)

Query: 118 PVKRERTSSLT-QFPPSQSEERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRPAV 176
           P KR R+SS T     SQS+            L+           Q P +  + V+RPA+
Sbjct: 69  PTKRVRSSSFTFHITDSQSQGVRKNNVFMTSALVQSSVDIKSA-EQGPVKHSKHVIRPAI 127

Query: 177 LQAPQPKALSQTVPSSGTNGVSLPADCTGAVPAASPDTAAWRSPSEAADEVCALEEKEPQ 236
           LQ PQ ++ ++   + G   +                            E C  +EK   
Sbjct: 128 LQLPQARSCAKVRKTFGHKAL----------------------------ESCKTKEKTNN 159

Query: 237 KNESSNASEEEACEKKDPATQQAFVFGQNLRDRVKLINESVDEADMENAGHPSADTPTAT 296
           K    N+                            L++E++  A +      + D   AT
Sbjct: 160 KISEGNSY---------------------------LLSENLSRARISVQLSTNQDFLGAT 192

Query: 297 NYFLQYISSSLENSTNSADASSNKFVFGQNMSERVLSPPKLNEVSSDANRENAAAESGSE 356
           +   Q      E+  +    SSN FVFG+NM ERVL   KL +   +   ++ A E   +
Sbjct: 193 SVGCQ----PNEDKCSFKSCSSN-FVFGENMVERVLGTQKLTQPQLE--NDSYAKEKPFK 245

Query: 357 S---------SSQEATPEKESLAESAAAYTKATARKCLLEKVEVITGEEAESNVLQMQCK 407
           S         SS+  + +  SL ESAAA++   +RKCLLEK++VITGEE E NVL++ CK
Sbjct: 246 SIPKFPVNFLSSRTDSIKNTSLIESAAAFSSQPSRKCLLEKIDVITGEETEHNVLKINCK 305

Query: 408 LFVFDKTSQSWVERGRGLLRLNDMASTDDGTLQSRLVMRTQGSLRLILNTKLWAQMQIDK 467
           LF+F+KT+QSW+ERGRG LRLND ASTD GTLQSRL+MR QGSLRLILN+KLWAQM+I +
Sbjct: 306 LFIFNKTTQSWIERGRGTLRLNDTASTDCGTLQSRLIMRNQGSLRLILNSKLWAQMKIQR 365

Query: 468 ASEKSIRITAMDTEDQGVKVFLISASSKDTGQLYAALHHRILALRSRVEQEQEAKMPAPE 527
           A+ K++RITA D ED  +K+FLI AS++DT  LYAA+HHR++AL+S  +Q    +  +  
Sbjct: 366 ANHKNVRITATDLEDYSIKIFLIQASAQDTAYLYAAIHHRLVALQSFNKQRDVNQAESLS 425

Query: 528 PGAAPSN-EEDDSDDDDVL 545
             A   N E  D ++DD +
Sbjct: 426 ETAQQLNCESCDENEDDFI 444


>gi|239582745 RAN binding protein 3-like isoform 1 [Homo sapiens]
          Length = 490

 Score =  233 bits (593), Expect = 5e-61
 Identities = 163/439 (37%), Positives = 230/439 (52%), Gaps = 78/439 (17%)

Query: 120 KRERTSSLTQ---FPPSQSEERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRPAV 176
           K+ R SS+T    FP S    +++ F             SA    Q P +  + V+RPA+
Sbjct: 96  KQMRCSSVTNLPTFPHSGPVRKNNVFMTSALVQSSVDIKSA---EQGPVKHSKHVIRPAI 152

Query: 177 LQAPQPKALSQTVPSSGTNGVSLPADCTGAVPAASPDTAAWRSPSEAADEVCALEEKEPQ 236
           LQ PQ ++ ++   + G   +                            E C  +EK   
Sbjct: 153 LQLPQARSCAKVRKTFGHKAL----------------------------ESCKTKEKTNN 184

Query: 237 KNESSNASEEEACEKKDPATQQAFVFGQNLRDRVKLINESVDEADMENAGHPSADTPTAT 296
           K    N+                            L++E++  A +      + D   AT
Sbjct: 185 KISEGNSY---------------------------LLSENLSRARISVQLSTNQDFLGAT 217

Query: 297 NYFLQYISSSLENSTNSADASSNKFVFGQNMSERVLSPPKLNEVSSDANRENAAAESGSE 356
           +   Q      E+  +    SSN FVFG+NM ERVL   KL +   +   ++ A E   +
Sbjct: 218 SVGCQ----PNEDKCSFKSCSSN-FVFGENMVERVLGTQKLTQPQLE--NDSYAKEKPFK 270

Query: 357 S---------SSQEATPEKESLAESAAAYTKATARKCLLEKVEVITGEEAESNVLQMQCK 407
           S         SS+  + +  SL ESAAA++   +RKCLLEK++VITGEE E NVL++ CK
Sbjct: 271 SIPKFPVNFLSSRTDSIKNTSLIESAAAFSSQPSRKCLLEKIDVITGEETEHNVLKINCK 330

Query: 408 LFVFDKTSQSWVERGRGLLRLNDMASTDDGTLQSRLVMRTQGSLRLILNTKLWAQMQIDK 467
           LF+F+KT+QSW+ERGRG LRLND ASTD GTLQSRL+MR QGSLRLILN+KLWAQM+I +
Sbjct: 331 LFIFNKTTQSWIERGRGTLRLNDTASTDCGTLQSRLIMRNQGSLRLILNSKLWAQMKIQR 390

Query: 468 ASEKSIRITAMDTEDQGVKVFLISASSKDTGQLYAALHHRILALRSRVEQEQEAKMPAPE 527
           A+ K++RITA D ED  +K+FLI AS++DT  LYAA+HHR++AL+S  +Q    +  +  
Sbjct: 391 ANHKNVRITATDLEDYSIKIFLIQASAQDTAYLYAAIHHRLVALQSFNKQRDVNQAESLS 450

Query: 528 PGAAPSN-EEDDSDDDDVL 545
             A   N E  D ++DD +
Sbjct: 451 ETAQQLNCESCDENEDDFI 469


>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens]
          Length = 2161

 Score = 56.6 bits (135), Expect = 6e-08
 Identities = 57/229 (24%), Positives = 78/229 (34%), Gaps = 30/229 (13%)

Query: 10   PAIAPPVFVFQKDKGQKSPAEQKNLSDSGEEPRGEAEAPHHGTGH---PESAGEHALEPP 66
            PA +P  F        +  + +K+L  SG  P      PHH   H   P+    HA  P 
Sbjct: 963  PASSPASFDGPSPPDTRVGSREKSLYHSGPLPPAHHHPPHHHHHHAPPPQPHHHHAHPPH 1022

Query: 67   APAGASASTPPPPAPEAQLPPFPRELAGRSAGGSSPEGGEDSDREDGN------------ 114
             P   +  +P  P P   L P P  L G   GG SP  G  S    G+            
Sbjct: 1023 PPEMETGGSPDDPPPRLALGPQP-SLRGWRGGGPSPTPGAPSPSHHGSAGGGGGSSQGPA 1081

Query: 115  ----YCPPVKRERTSSLTQFPPSQSEERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRS 170
                  PP    R +S   + P++S     G  +K   +        GLP         S
Sbjct: 1082 LRYFQLPP----RAASAAMYVPARSGRGRKGPLVKQTKVEGEPQKGGGLPPAPSPTSPAS 1137

Query: 171  VLRPAVLQAPQPK------ALSQTVPSSGTNGVSLPADCTGAVPAASPD 213
               P  + AP  K       +    PS+ ++G S     T A P   P+
Sbjct: 1138 PQPPPAVAAPSEKNSIPIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQPE 1186



 Score = 37.4 bits (85), Expect = 0.037
 Identities = 56/195 (28%), Positives = 73/195 (37%), Gaps = 28/195 (14%)

Query: 41   PRGEAEAPHHGTGHPESAGEHALEPPAPAGASASTPPPPAPEAQLPPFPRELAGRSAGGS 100
            P G A A         S G  A +PP    +     PPP P    P    E   R  G S
Sbjct: 1352 PLGLALAARERALKESSEGGGAPQPPPRPPSPRYEAPPPTPHHHSPHAHHEPVLRLWGAS 1411

Query: 101  SPEGGEDSDREDGNYCPPVKRERTSSLTQFPPSQSEERSSGFRLKP------PTLIH-GQ 153
             P   + + RE G       +E+  SL   PP  +  RS   RL P      P L+  G 
Sbjct: 1412 PP---DPARRELGYRAGLGSQEK--SLPASPP--AARRSLLHRLPPTAPGVGPLLLQLGT 1464

Query: 154  APSAGLP-------SQKPKEQQRSVLRPAVLQAPQPKALSQTVPSSGTNGVSLPADCTGA 206
             P A  P       S  P+E +R  L    L+  QP+A         T+G   P++    
Sbjct: 1465 EPPAPHPGVSKPWRSAAPEEPERLPLHVRFLENCQPRA-------PVTSGRGPPSEDGPG 1517

Query: 207  VPAASPDTAAWRSPS 221
            VP  SP  +   SP+
Sbjct: 1518 VPPPSPRRSVPPSPT 1532



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 42/164 (25%), Positives = 55/164 (33%), Gaps = 17/164 (10%)

Query: 64   EPPAPAGASASTPPPPAPEA--QLPPFPRELAGRSAGGSSPEGGEDSDREDGNYCPPVKR 121
            EPPAP    +      APE   +LP   R L       +    G     EDG   PP   
Sbjct: 1465 EPPAPHPGVSKPWRSAAPEEPERLPLHVRFLENCQPR-APVTSGRGPPSEDGPGVPPPSP 1523

Query: 122  ERTSSLTQFPPSQSEERSSGFRLKPPTLIHGQAPSAGL---------PSQKPKEQQRSVL 172
             R+      PPS +  R+S     P  ++   APS  +         P   P E   S  
Sbjct: 1524 RRS-----VPPSPTSPRASEENGLPLLVLPPPAPSVDVEDGEFLFVEPLPPPLEFSNSFE 1578

Query: 173  RPAVLQAPQPKALSQTVPSSGTNGVSLPADCTGAVPAASPDTAA 216
            +P     P P       P+  T    +P     A P     TA+
Sbjct: 1579 KPESPLTPGPPHPLPDTPAPATPLPPVPPPAVAAAPPTLDSTAS 1622



 Score = 31.6 bits (70), Expect = 2.0
 Identities = 24/101 (23%), Positives = 35/101 (34%), Gaps = 1/101 (0%)

Query: 5    ANEEKPAIAPPVFVFQKDKGQKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGEHALE 64
            A  EK +I  P  + +      S    +  S   E P         G G    +   A+ 
Sbjct: 1146 APSEKNSIPIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQPEPTGGGGGGGSSPSPAPAMS 1205

Query: 65   PPAPAGASASTPPPPAPEAQLPPFPRELAGRSAGGSSPEGG 105
            P  P+ +   TP  P+  A L  F  +      G +  EGG
Sbjct: 1206 PVPPSPSPVPTPASPSGPATL-DFTSQFGAALVGAARREGG 1245


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 92/379 (24%), Positives = 145/379 (38%), Gaps = 74/379 (19%)

Query: 24   GQKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGEHALEPPAPAGA--SASTPPPPAP 81
            G  +P    N   S   P+  A A   G   P SA  HA  P   AG+  +A+  P    
Sbjct: 2313 GSGTPPTAANYPSSSRTPQAPASANLVG---PRSA--HATAPVNIAGSRTAAALAPASLT 2367

Query: 82   EAQLPPFPRELAGRSAGGSSPEGGEDS-DREDGNYCPPVKRERTSSLTQFPPSQSEERSS 140
             A++ P     A   A  +SP     + +R  G   PP+     S      PSQS  R +
Sbjct: 2368 SARMAP-----ALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQS--RMT 2420

Query: 141  GFRLKPPTLIHGQAPSAGL--PSQKPKEQQRSVLRPAVLQAPQPKALSQTVPSSGTNGVS 198
              R   P+   GQAPS  L  P+Q   +Q RS + P+         ++QT P +G+  +S
Sbjct: 2421 SERAPSPSSRMGQAPSQSLLPPAQ---DQPRSPV-PSAFSDQSRCLIAQTTPVAGSQSLS 2476

Query: 199  LPADCTG-----------AVPAAS-PDTAAWRSPSEAADE----VCALEEKEPQKNESSN 242
              A  T            +VPA   P +     P+    +    + AL+  + +++ SS+
Sbjct: 2477 SGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSS 2536

Query: 243  ASEEEACEKKDPATQQAFVFGQNLRD---------------RVKLINESVDEADMENAGH 287
            +S   +      ++  +   G +  D               RV     +  EA  E  G 
Sbjct: 2537 SSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVRE--GR 2594

Query: 288  PSADTPTATNYFLQYISSSLENSTNSADASSNKFVFGQNMSERVLSPPKLNEVSSDANRE 347
            P   TP          SSS  +S++S+ +SS+                     SS ++  
Sbjct: 2595 PPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSS--------------------SSSSSSS 2634

Query: 348  NAAAESGSESSSQEATPEK 366
            ++++ S S SSS   +P K
Sbjct: 2635 SSSSSSSSSSSSSSPSPAK 2653



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 50/172 (29%), Positives = 69/172 (40%), Gaps = 23/172 (13%)

Query: 21   KDKGQKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGEHALEPPAPAGASASTPPPPA 80
            KDK + +P  Q   SDS  EP+  A AP        S        P+P G+S++   P  
Sbjct: 1605 KDKPRAAPRAQSG-SDSSPEPK--APAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEH 1661

Query: 81   PEAQLPPFPRELAGRSAGGSSPEGGEDS----DREDGNYCPPVKRE-RTSSLTQFPPSQS 135
            P       P+    R    SSPE    S     R      P + R+ R S  ++   S  
Sbjct: 1662 P-------PKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSP 1714

Query: 136  EERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRPAVLQAPQPKALSQ 187
            E RS      PP   H ++PS   P  +P E+ RS  R     +P+ K  S+
Sbjct: 1715 ETRSR----TPPR--HRRSPSVSSP--EPAEKSRSSRRRRSASSPRTKTTSR 1758



 Score = 35.4 bits (80), Expect = 0.14
 Identities = 81/415 (19%), Positives = 143/415 (34%), Gaps = 37/415 (8%)

Query: 21   KDKGQKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGEHALEPPAPAGASASTPPP-- 78
            + K +   + +++LS S   P+ +++ P   +    S  +     P     S+S+PPP  
Sbjct: 766  RSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQ 825

Query: 79   --PAPEAQ----LPPFPRELAG---RSAGGSSPEGGEDSDREDGNYC-----PPVKRERT 124
                P  Q      P P+  +G   R    +SP+  E S       C      P  + RT
Sbjct: 826  KSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRT 885

Query: 125  SS------------LTQFPPSQSEERSSGFRLKPPTLIH-GQAPSAGLPSQKP-KEQQRS 170
             S             +  PP QS  RSS  + K   +I   Q   +G  S  P +   R+
Sbjct: 886  PSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRT 945

Query: 171  VLRPAVLQAPQPKALSQTVPSSGTNGVSLPADCTGAVPAASPDTAAWRSPSEAADEVCAL 230
              R +   +P     S+ +P    +G S P           P+T   +S S +      +
Sbjct: 946  TPRRSRSVSPCSNVESRLLPRYSHSGSSSPD------TKVKPETPPRQSHSGSISPYPKV 999

Query: 231  EEKEPQKNESSNASEEEACEKKDPATQQAFVFGQNLRDRVKLINESVDEADMENAGHPSA 290
            + + P     S +      EK   +  Q+     +L   VK      +     ++     
Sbjct: 1000 KAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKG 1059

Query: 291  DTPTATNYFLQYISSSLENSTNSADASSNKFVFGQNMSERVLSPPKLNEVSSDANRENAA 350
             + T+ ++     S  +  S + + +  +K            S P     S    R++  
Sbjct: 1060 QSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRG 1119

Query: 351  AESGSESSSQEATPEKESLAESAAAYTKATARKCLLEKVEVITGEEAESNVLQMQ 405
              S S       +PE+      +++Y    +   LL +  + T E  E   L  Q
Sbjct: 1120 EFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNS-LLGQSRLETAESKEKMALPPQ 1173



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 34/152 (22%), Positives = 51/152 (33%), Gaps = 15/152 (9%)

Query: 20   QKDKGQKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGEHALEPPAPAGASASTPPPP 79
            +K +   S +   + S S       + +    +    S+   +   P+PA       P P
Sbjct: 2603 RKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKP 2662

Query: 80   APEAQLPPFPRELAGRSAGGSSPEGGEDSDREDGNYC-PPVKRERTSSLTQFPPSQSEER 138
            A   + PP  R          SP    DS R+  +    PV+R R S        QS   
Sbjct: 2663 ASPKKPPPGERR-------SRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSS 2715

Query: 139  SSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRS 170
              G R        GQ   +  PS K + +  S
Sbjct: 2716 ERGSR-------RGQRGDSRSPSHKRRRETPS 2740



 Score = 30.8 bits (68), Expect = 3.5
 Identities = 43/185 (23%), Positives = 61/185 (32%), Gaps = 40/185 (21%)

Query: 21  KDKGQKSPAEQKNLSDSGEEP------RGEAEAPHHGTG-----HPESAGEHALEPPAP- 68
           + + + + A+    + +G  P      RGE +AP    G      P S      +P +P 
Sbjct: 276 RSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPY 335

Query: 69  ------AGASASTPPPPAPEAQL----PPFPRELAGRSAGGSSPEGGEDSDREDGNYCPP 118
                     ++T P P+PE       PP P  L     GGS                 P
Sbjct: 336 EDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQ---------------P 380

Query: 119 VKRERTSSLTQFPPSQSEERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRPAVLQ 178
           +    T+ L+Q P +   E S      PP        S+   S  P  Q   V R A   
Sbjct: 381 LA---TTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSS 437

Query: 179 APQPK 183
              PK
Sbjct: 438 PESPK 442


>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
           sapiens]
          Length = 699

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 87/419 (20%), Positives = 155/419 (36%), Gaps = 54/419 (12%)

Query: 2   ADLANEEKPAIAPPVFVFQKDKGQKSPAE--------QKNLSDSGEEPRGEAEAPHHGTG 53
           +D + EEK A  P   V +K    K+P +          +  DS  +   E + P     
Sbjct: 227 SDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKP 286

Query: 54  HPESAGEHALEPPAPAGASASTPPPPAPEAQLPPFPRELAGRSAGGSSPEGGEDSDREDG 113
            P S+      PP P  +  + PP  A E Q P         S+  SS E    S+ E  
Sbjct: 287 GPYSSVPPPSAPP-PKKSLGTQPPKKAVEKQQPV-------ESSEDSSDESDSSSEEEKK 338

Query: 114 NYCPPVKRERTSSLTQFPPSQSEERSSGFRLKPPTLIHGQAPS--AGLPSQKPKEQQRSV 171
              PP K   + + T+ PP++    SS       +    +APS  AG       +   + 
Sbjct: 339 ---PPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTT 395

Query: 172 LRPAVLQAPQPK---ALSQTVPSSGTNGVSLPADCTGAVPAASPDTAAWRSPSEAADEVC 228
             PAV  A  PK      Q + +   +  S   + + +    +    A   P   A    
Sbjct: 396 KSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAAL 455

Query: 229 ALEEKE-PQ-KNESSNASEEEACEKKDPATQQAFVFGQNLRDRVKLINESVDEADMENAG 286
           +L  K+ PQ   +SS+ S+  + E+++  T ++                +V +   + AG
Sbjct: 456 SLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKS----------------AVKKKPQKVAG 499

Query: 287 HPSADTPTATNYFLQYISSSLENSTNSADASSNKFVFGQNMSERVLSPPKLNEVSSDANR 346
             +   P +     +   +   NS++S D+S  +    +         PK N  S+   +
Sbjct: 500 GAAPSKPASA----KKGKAESSNSSSSDDSSEEEEEKLKGKGSPRPQAPKANGTSALTAQ 555

Query: 347 ENAAAESGSESSSQEATPEKESLAESAAAYTKATARKCLLEKVEVITGEEAESNVLQMQ 405
              AA++  E        E+E   ++A   +K+ + K   +       E  ++  +++Q
Sbjct: 556 NGKAAKNSEE--------EEEEKKKAAVVVSKSGSLKKRKQNEAAKEAETPQAKKIKLQ 606



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 74/336 (22%), Positives = 123/336 (36%), Gaps = 41/336 (12%)

Query: 56  ESAGEHALEPPAPAGASASTPPPPAPEAQLPPFPRELAGRSAGGSSPEGGEDSDREDGNY 115
           E + E   E   P    A+ P   A    LPP   + A +++  SS E   D D E+   
Sbjct: 88  EDSSEEEEEVQGPPAKKAAVP---AKRVGLPP--GKAAAKASESSSSEESSDDDDEEDQK 142

Query: 116 CPPVKR--ERTSSLTQFPPSQSEERSSGFRLKPPTLIHGQAPSAGLPSQKP---KEQQRS 170
             PV++  +  +   + PP +++   S       +    + P    P   P   K Q ++
Sbjct: 143 KQPVQKGVKPQAKAAKAPPKKAKSSDS----DSDSSSEDEPPKNQKPKITPVTVKAQTKA 198

Query: 171 VLRPAVLQAPQPKALSQTVPSSGTNGVSLPADCTGAVPAASPDTAAWRSPSEAADEVCAL 230
             +PA   AP+         SS ++  S   D      AA+P     +    A   V A 
Sbjct: 199 PPKPA-RAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAA 257

Query: 231 EEKEPQKNESSNASEEEACEKKDPATQQAFVFGQNLRDRVKLINESVDEADMENAGHPSA 290
                + + S ++S +E  E+K P   +   +             SV             
Sbjct: 258 TTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPY------------SSVPPPSAPPPKKSLG 305

Query: 291 DTPTATNYFLQYISSSLENSTNSADASSNKFVFGQNMSERVLSPPKLNEVSSDANR---E 347
             P       Q    S E+S++ +D+S          SE    PP    VS    +    
Sbjct: 306 TQPPKKAVEKQQPVESSEDSSDESDSS----------SEEEKKPPTKAVVSKATTKPPPA 355

Query: 348 NAAAESGSESSSQEATPEKESLAESAAAYTKATARK 383
             AAES S+SS  +++ + E+ ++ A   TK ++ K
Sbjct: 356 KKAAESSSDSSDSDSSEDDEAPSKPAGT-TKNSSNK 390



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 56/299 (18%), Positives = 110/299 (36%), Gaps = 26/299 (8%)

Query: 2   ADLANEEKPAIAPPVFVFQKDKGQKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGEH 61
           +D ++EE+    PP          K P  +K    S +    ++         P    ++
Sbjct: 329 SDSSSEEEKK--PPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKN 386

Query: 62  ALEPPAPAGASASTPPPPAPEAQLPPFPRELAGRSAGGSSPEGGEDSDREDGNYCPPVKR 121
           +   PA    S +  P  AP+  +    + L  ++   SS E    S+ E         +
Sbjct: 387 SSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTK 446

Query: 122 ERTS--SLTQFPPSQSEERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRPAVLQA 179
            + +  +    P  Q+ + S             +  S+   S   +E++    + AV + 
Sbjct: 447 PKATAKAALSLPAKQAPQGS-------------RDSSSDSDSSSSEEEEEKTSKSAVKKK 493

Query: 180 PQPKA--LSQTVPSSGTNGVSLPADCTGAVPAASPDTAAWR---SPSEAADEVCALEEKE 234
           PQ  A   + + P+S   G +  ++ + +  ++  +    +   SP   A +        
Sbjct: 494 PQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKGSPRPQAPKANGTSALT 553

Query: 235 PQKNESSNASEEEACEKKDPATQQAFVFGQNLRDRVKLINESVDEADMENAGHPSADTP 293
            Q  +++  SEEE  EKK    + A V  ++   + +  NE+  EA+   A      TP
Sbjct: 554 AQNGKAAKNSEEEEEEKK----KAAVVVSKSGSLKKRKQNEAAKEAETPQAKKIKLQTP 608


>gi|24308394 hypothetical protein LOC140893 [Homo sapiens]
          Length = 664

 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 52/208 (25%), Positives = 77/208 (37%), Gaps = 31/208 (14%)

Query: 51  GTGHPESAGEHALEPPAPAGASASTPPPPAPEAQLPPFPRELAGRSAGGSSPEGGEDSDR 110
           G   P+ AG+H     +PA A  ++P PP     L   P+ L+  + G   PE  E S  
Sbjct: 452 GQDTPKPAGQHG--SLSPAAAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEASTP 509

Query: 111 EDGNYCPPVKRERTSSLTQFPPSQSEERSSGFRLKPPTLIHGQAPSAGLPSQ---KPKEQ 167
            D     P +    S L+   P  +E+  +G  L PP   H Q P    P      P+  
Sbjct: 510 MD-----PSRPLPGSQLSLSSPGSTEDEDTGRPLPPP---HPQPPPHPQPPDLDGHPEPS 561

Query: 168 QRSVLRPAVLQAPQPKALSQTVPSSGTNGVSLPADCTGAVPAASPDTAAWRSPSEAADEV 227
           +  VLR      P+   L +T       G+S  A+ T +     P+             +
Sbjct: 562 KAEVLR------PESDELDETDTPGSEVGLSSQAEATTSTTGEGPEC------------I 603

Query: 228 CALEEKEPQKNESSNASEEEACEKKDPA 255
           C  E  +    +   ASE      K P+
Sbjct: 604 CTQEHGQGPPRKRKRASEPGDKASKKPS 631


>gi|169162953 PREDICTED: RANBP2-like and GRIP domain containing 8
            [Homo sapiens]
          Length = 1765

 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 35/111 (31%), Positives = 58/111 (52%), Gaps = 6/111 (5%)

Query: 387  EKVEVITGEEAESNVLQMQCKLFVFDKTSQSWVERGRGLLRLNDMASTDDGTLQSRLVMR 446
            EKVE++TGEE E  +     KLF FD   + W ERG G L++  + +  +G L  R++MR
Sbjct: 1045 EKVELVTGEEGEKVLYSQGVKLFRFDAEVRQWKERGLGNLKI--LKNEVNGKL--RMLMR 1100

Query: 447  TQGSLRLILNTKLWAQMQID--KASEKSIRITAMDTEDQGVKVFLISASSK 495
             +  L++  N  +   M +     S+++   +A D  D   K+  ++A  K
Sbjct: 1101 REQVLKVCANHWITTTMNLKPLSGSDRAWMWSASDFSDGDAKLERLAAKFK 1151



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 56/224 (25%), Positives = 96/224 (42%), Gaps = 36/224 (16%)

Query: 268  DRVKLINESVDEADMENAGH--PSADTPTATNYFLQYISSSLENSTNSADASSNKFVFGQ 325
            D   L  +++D++   ++ H  P A +P   N F        + ST  ++ S   F    
Sbjct: 1249 DNYDLREDALDDSVSSSSVHASPLASSPVRKNLF------RFDESTTGSNFS---FKSAL 1299

Query: 326  NMSERVLSPPKLNEVSSDANRENAAAESGSESSSQEATPEKESLAESAAAYTKATARKCL 385
            ++S+   SP KLN+  +    +  +  +  E              E    Y +      L
Sbjct: 1300 SLSK---SPAKLNQSGTSVGTDEESVVTQEE--------------ERDGQYFEPVVP--L 1340

Query: 386  LEKVEVITGEEAESNVLQMQCKLFVFDKTSQSWVERGRGLLRLNDMASTDDGTLQSRLVM 445
             + VEV +GEE E  V   + +++ +DK    W ERG G +++  + + D+   Q R+VM
Sbjct: 1341 PDLVEVSSGEENEQVVFSHRAEIYRYDKDVGQWKERGIGDIKI--LQNYDN--KQVRIVM 1396

Query: 446  RTQGSLRLILNTKLWAQMQID--KASEKSIRITAMDTEDQGVKV 487
            R    L+L  N ++   M +   K +E+    TA D  D   KV
Sbjct: 1397 RRDQVLKLCANHRITPDMSLQNMKGTERVWVWTACDFADGERKV 1440


>gi|83267877 RANBP2-like and GRIP domain containing 5 isoform 1 [Homo
            sapiens]
          Length = 1765

 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 35/111 (31%), Positives = 58/111 (52%), Gaps = 6/111 (5%)

Query: 387  EKVEVITGEEAESNVLQMQCKLFVFDKTSQSWVERGRGLLRLNDMASTDDGTLQSRLVMR 446
            EKVE++TGEE E  +     KLF FD   + W ERG G L++  + +  +G L  R++MR
Sbjct: 1045 EKVELVTGEEGEKVLYSQGVKLFRFDAEVRQWKERGLGNLKI--LKNEVNGKL--RMLMR 1100

Query: 447  TQGSLRLILNTKLWAQMQID--KASEKSIRITAMDTEDQGVKVFLISASSK 495
             +  L++  N  +   M +     S+++   +A D  D   K+  ++A  K
Sbjct: 1101 REQVLKVCANHWITTTMNLKPLSGSDRAWMWSASDFSDGDAKLERLAAKFK 1151



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 56/224 (25%), Positives = 96/224 (42%), Gaps = 36/224 (16%)

Query: 268  DRVKLINESVDEADMENAGH--PSADTPTATNYFLQYISSSLENSTNSADASSNKFVFGQ 325
            D   L  +++D++   ++ H  P A +P   N F        + ST  ++ S   F    
Sbjct: 1249 DNYDLREDALDDSVSSSSVHASPLASSPVRKNLF------RFDESTTGSNFS---FKSAL 1299

Query: 326  NMSERVLSPPKLNEVSSDANRENAAAESGSESSSQEATPEKESLAESAAAYTKATARKCL 385
            ++S+   SP KLN+  +    +  +  +  E              E    Y +      L
Sbjct: 1300 SLSK---SPAKLNQSGTSVGTDEESVVTQEE--------------ERDGQYFEPVVP--L 1340

Query: 386  LEKVEVITGEEAESNVLQMQCKLFVFDKTSQSWVERGRGLLRLNDMASTDDGTLQSRLVM 445
             + VEV +GEE E  V   + +++ +DK    W ERG G +++  + + D+   Q R+VM
Sbjct: 1341 PDLVEVSSGEENEQVVFSHRAEIYRYDKDVGQWKERGIGDIKI--LQNYDN--KQVRIVM 1396

Query: 446  RTQGSLRLILNTKLWAQMQID--KASEKSIRITAMDTEDQGVKV 487
            R    L+L  N ++   M +   K +E+    TA D  D   KV
Sbjct: 1397 RRDQVLKLCANHRITPDMSLQNMKGTERVWVWTACDFADGERKV 1440


>gi|182765478 RANBP2-like and GRIP domain containing 6 [Homo sapiens]
          Length = 1765

 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 35/111 (31%), Positives = 58/111 (52%), Gaps = 6/111 (5%)

Query: 387  EKVEVITGEEAESNVLQMQCKLFVFDKTSQSWVERGRGLLRLNDMASTDDGTLQSRLVMR 446
            EKVE++TGEE E  +     KLF FD   + W ERG G L++  + +  +G L  R++MR
Sbjct: 1045 EKVELVTGEEGEKVLYSQGVKLFRFDAEVRQWKERGLGNLKI--LKNEVNGKL--RMLMR 1100

Query: 447  TQGSLRLILNTKLWAQMQID--KASEKSIRITAMDTEDQGVKVFLISASSK 495
             +  L++  N  +   M +     S+++   +A D  D   K+  ++A  K
Sbjct: 1101 REQVLKVCANHWITTTMNLKPLSGSDRAWMWSASDFSDGDAKLERLAAKFK 1151



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 56/224 (25%), Positives = 96/224 (42%), Gaps = 36/224 (16%)

Query: 268  DRVKLINESVDEADMENAGH--PSADTPTATNYFLQYISSSLENSTNSADASSNKFVFGQ 325
            D   L  +++D++   ++ H  P A +P   N F        + ST  ++ S   F    
Sbjct: 1249 DNYDLREDALDDSVSSSSVHASPLASSPVRKNLF------RFDESTTGSNFS---FKSAL 1299

Query: 326  NMSERVLSPPKLNEVSSDANRENAAAESGSESSSQEATPEKESLAESAAAYTKATARKCL 385
            ++S+   SP KLN+  +    +  +  +  E              E    Y +      L
Sbjct: 1300 SLSK---SPAKLNQSGTSVGTDEESVVTQEE--------------ERDGQYFEPVVP--L 1340

Query: 386  LEKVEVITGEEAESNVLQMQCKLFVFDKTSQSWVERGRGLLRLNDMASTDDGTLQSRLVM 445
             + VEV +GEE E  V   + +++ +DK    W ERG G +++  + + D+   Q R+VM
Sbjct: 1341 PDLVEVSSGEENEQVVFSHRAEIYRYDKDVGQWKERGIGDIKI--LQNYDN--KQVRIVM 1396

Query: 446  RTQGSLRLILNTKLWAQMQID--KASEKSIRITAMDTEDQGVKV 487
            R    L+L  N ++   M +   K +E+    TA D  D   KV
Sbjct: 1397 RRDQVLKLCANHRITPDMSLQNMKGTERVWVWTACDFADGERKV 1440


>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
           preproprotein [Homo sapiens]
          Length = 331

 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 45/160 (28%), Positives = 54/160 (33%), Gaps = 24/160 (15%)

Query: 14  PPVFVFQKDKGQKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGEHALEPPAPAGASA 73
           PP    +K +G   P + +     G++ R     P    G P   G     PP P G   
Sbjct: 182 PPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQ 241

Query: 74  STPPPPAPEAQLPPFPRELAGRSAGGSSPEGGEDSDREDGNYCPPVKRERTSSLTQFPPS 133
             PP    + Q PP P +  G  A G S      S        PP K        Q PP 
Sbjct: 242 GPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARS--------PPGK-------PQGPPQ 286

Query: 134 QSEERSSGFRLKPPTLIHG-----QAPSAGLPSQKPKEQQ 168
           Q      G    PP    G     QAP AG P   P+  Q
Sbjct: 287 QEGNNPQG----PPPPAGGNPQQPQAPPAGQPQGPPRPPQ 322



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 39/151 (25%), Positives = 51/151 (33%), Gaps = 17/151 (11%)

Query: 14  PPVFVFQKDKGQKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGEHALEPPAPAGASA 73
           PP     + +G   P + +     G++ R     P    G P   G     PP P G   
Sbjct: 121 PPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ 180

Query: 74  STPPPPAPEAQLPPFPRELAGRSAGGSSPEGGEDSDREDGNYCPPVKRERTSSLTQFPPS 133
             PP    + Q PP P +       G  P+G    D+   +  PP K        Q PP 
Sbjct: 181 GPPPQGGKKPQGPPPPGK-----PQGPPPQG----DKSRSSQSPPGK-------PQGPPP 224

Query: 134 QSEERSSGFRLKPPTLIHGQAPSAGLPSQKP 164
           Q   +  G    PP    G  P  G   Q P
Sbjct: 225 QGGNQPQG-PPPPPGKPQGPPPQGGNKPQGP 254



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 44/170 (25%), Positives = 54/170 (31%), Gaps = 24/170 (14%)

Query: 14  PPVFVFQKDKGQKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGEHALEPPAPAGASA 73
           PP     K +G   P + +     G++ R     P    G P   G     PP P G   
Sbjct: 60  PPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ 119

Query: 74  STPPPPAPEAQLPPFPRELAGRSAGGSSPEGGEDSDREDGNYCPPVKRERTSSLTQFPPS 133
             PP      Q PP P +       G  P+G    D+      PP K        Q PP 
Sbjct: 120 GPPPQGGNRPQGPPPPGK-----PQGPPPQG----DKSRSPRSPPGK-------PQGPPP 163

Query: 134 QSEERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRPAVLQAPQPK 183
           Q   +  G    PP    G  P  G   Q P         P   Q P P+
Sbjct: 164 QGGNQPQG-PPPPPGKPQGPPPQGGKKPQGPPP-------PGKPQGPPPQ 205



 Score = 39.3 bits (90), Expect = 0.010
 Identities = 47/185 (25%), Positives = 64/185 (34%), Gaps = 38/185 (20%)

Query: 3   DLANEEKPAIAPPVFVFQKDKGQKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGEHA 62
           D++ EE P++             + P+ Q      G +P+G    P    G P   G   
Sbjct: 22  DVSQEESPSLIAG--------NPQGPSPQ-----GGNKPQGPPPPPGKPQGPPPQGGNKP 68

Query: 63  LEPPAPAGASASTPPPPAPEAQLPPFPRELAGRSAGGSSPEGGEDSDREDGNYCPPVKRE 122
             PP P       P  P P+      PR   G+   G  P+GG   ++  G   PP K  
Sbjct: 69  QGPPPP-----GKPQGPPPQGDKSRSPRSPPGKPQ-GPPPQGG---NQPQGPPPPPGK-- 117

Query: 123 RTSSLTQFPPSQSEERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRPAVLQAPQP 182
                 Q PP Q   R  G    PP       P  G  S+ P+        P   Q P P
Sbjct: 118 -----PQGPPPQGGNRPQG---PPPPGKPQGPPPQGDKSRSPRSP------PGKPQGPPP 163

Query: 183 KALSQ 187
           +  +Q
Sbjct: 164 QGGNQ 168



 Score = 35.0 bits (79), Expect = 0.18
 Identities = 45/177 (25%), Positives = 55/177 (31%), Gaps = 28/177 (15%)

Query: 40  EPRGEAEAPHHGTGHPES----AGEHALEPPAPAGASASTPPPPAPEAQLPPFPRELAGR 95
           E   + E+P    G+P+      G     PP P G     PP    + Q PP P +    
Sbjct: 21  EDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK---- 76

Query: 96  SAGGSSPEGGEDSDREDGNYCPPVKRERTSSLTQFPPSQSEERSSGFRLKPPTLIHGQAP 155
              G  P+G    D+      PP K        Q PP Q   +  G    PP    G  P
Sbjct: 77  -PQGPPPQG----DKSRSPRSPPGK-------PQGPPPQGGNQPQG-PPPPPGKPQGPPP 123

Query: 156 SAGLPSQKPKEQQRSVLRPAVLQAPQPKALSQTVPSSGTNGVSLPADCTGAVPAASP 212
             G   Q P         P   Q P P+      P S       P    G  P   P
Sbjct: 124 QGGNRPQGPPP-------PGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPP 173



 Score = 34.7 bits (78), Expect = 0.24
 Identities = 26/86 (30%), Positives = 35/86 (40%), Gaps = 11/86 (12%)

Query: 9   KPAIAPPVFVFQKDKGQKSPAEQKNLSDSGEEPRGEAEAP-----HHGTGHPESAGEHAL 63
           KP   PP       K Q  PA+  + S S   P G+ + P     ++  G P  AG +  
Sbjct: 250 KPQGPPP-----PGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQ 304

Query: 64  EPPAPAGASASTPPPPAPEAQLPPFP 89
           +P AP       PP P P+   P  P
Sbjct: 305 QPQAPPAGQPQGPPRP-PQGGRPSRP 329


>gi|150418007 RAN binding protein 2 [Homo sapiens]
          Length = 3224

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 35/111 (31%), Positives = 57/111 (51%), Gaps = 6/111 (5%)

Query: 387  EKVEVITGEEAESNVLQMQCKLFVFDKTSQSWVERGRGLLRLNDMASTDDGTLQSRLVMR 446
            EKVE++TGEE E  +   + KLF FD     W ERG G L++  + +  +G L  R++MR
Sbjct: 2021 EKVELVTGEEDEKVLYSQRVKLFRFDAEVSQWKERGLGNLKI--LKNEVNGKL--RMLMR 2076

Query: 447  TQGSLRLILNTKLWAQMQID--KASEKSIRITAMDTEDQGVKVFLISASSK 495
             +  L++  N  +   M +     S+++    A D  D   K+  ++A  K
Sbjct: 2077 REQVLKVCANHWITTTMNLKPLSGSDRAWMWLASDFSDGDAKLEQLAAKFK 2127



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 52/183 (28%), Positives = 81/183 (44%), Gaps = 24/183 (13%)

Query: 313  SADASSNKFVFGQNMS------ERVLSPPKLNEVSSDANRENAAAESGSESSSQEATPEK 366
            S+    N F FG++ +      +  LSP K     S A    +    G++  S + T E+
Sbjct: 2250 SSPVRKNLFRFGESTTGFNFSFKSALSPSK-----SPAKLNQSGTSVGTDEES-DVTQEE 2303

Query: 367  ESLAESAAAYTKATARKCLLEKVEVITGEEAESNVLQMQCKLFVFDKTSQSWVERGRGLL 426
            E   +             L + VEV +GEE E  V   + KL+ +DK    W ERG G +
Sbjct: 2304 ERDGQYFEPVVP------LPDLVEVSSGEENEQVVFSHRAKLYRYDKDVGQWKERGIGDI 2357

Query: 427  RLNDMASTDDGTLQSRLVMRTQGSLRLILNTKLWAQMQID--KASEKSIRITAMDTEDQG 484
            ++  + + D+   Q R+VMR    L+L  N ++   M +   K +E+    TA D  D  
Sbjct: 2358 KI--LQNYDN--KQVRIVMRRDQVLKLCANHRITPDMTLQNMKGTERVWLWTACDFADGE 2413

Query: 485  VKV 487
             KV
Sbjct: 2414 RKV 2416



 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 33/101 (32%), Positives = 54/101 (53%), Gaps = 6/101 (5%)

Query: 385  LLEKVEVITGEEAESNVLQMQCKLFVFDKTSQSWVERGRGLLRLNDMASTDDGTLQSRLV 444
            L +K+EV TGEE E      + KLF FD  S+ W ERG G +++  +     G +  RL+
Sbjct: 1178 LPDKIEVKTGEEDEEEFFCNRAKLFRFDVESKEWKERGIGNVKI--LRHKTSGKI--RLL 1233

Query: 445  MRTQGSLRLILNTKLWAQMQI--DKASEKSIRITAMDTEDQ 483
            MR +  L++  N  +   M++  +  S++S    A+D  D+
Sbjct: 1234 MRREQVLKICANHYISPDMKLTPNAGSDRSFVWHALDYADE 1274



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 29/106 (27%), Positives = 51/106 (48%), Gaps = 10/106 (9%)

Query: 386  LEKVEVITGEEAESNVLQMQCKLFVFDKTSQSWVERGRGLLRL--NDMASTDDGTLQSRL 443
            L +VEV +GEE E  + + + KL+ +D+    W ERG G +++  + M +        R+
Sbjct: 2918 LPEVEVKSGEEDEEILFKERAKLYRWDRDVSQWKERGVGDIKILWHTMKN------YYRI 2971

Query: 444  VMRTQGSLRLILNTKLWAQMQID--KASEKSIRITAMDTEDQGVKV 487
            +MR     ++  N  +   M++     S  ++  TA D  D   KV
Sbjct: 2972 LMRRDQVFKVCANHVITKTMELKPLNVSNNALVWTASDYADGEAKV 3017


>gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]
          Length = 825

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 98/430 (22%), Positives = 161/430 (37%), Gaps = 77/430 (17%)

Query: 5   ANEEKPA-IAPPVFVFQKDKGQKSPAEQKNLS---DSGEEPRGEAEAPHHGTGHPESAGE 60
           + E+ PA I PP+      K +  PAE+ ++     + E P  EA               
Sbjct: 261 STEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQPSTEETPDAEAAT------------- 307

Query: 61  HALEPPAPAGASASTPPPPAPEAQLPPFPRELAGRSAGGSS---------PEGGEDSDRE 111
                 A A  S    PPPA EA L  FP E+   SA  S          P   E+S  E
Sbjct: 308 ------AVAENSVKVQPPPAEEAPLVEFPAEIQPPSAEESPSVELLAEILPPSAEESPSE 361

Query: 112 D--GNYCPPVKRE----------RTSSLTQFP------PSQSEERSSGFRLKPPTLIHGQ 153
           +      PP   +          R+ S  + P      P++     +  +++PPT+    
Sbjct: 362 EPPAEILPPPAEKSPSVELLGEIRSPSAQKAPIEVQPLPAEGALEEAPAKVEPPTVEETL 421

Query: 154 AP-SAGLPSQKPKEQQRSVLRPAVLQAPQPKALSQTVPSSGTNGVSLPADCTGAVPAASP 212
           A     LP + P+E+ R +     ++ P  +A ++           LP + T    +A  
Sbjct: 422 ADVQPLLPEEAPREEARELQLSTAMETPAEEAPTEFQS-------PLPKETTAEEASAEI 474

Query: 213 DTAAWRSPSEAADEVCALEEKEPQKNESSNASEEEACEKKDPATQQAFVFGQNLRDRVKL 272
              A   P   ADE  A E + P   E+S  +EE   E + P  ++     +     ++L
Sbjct: 475 QLLAATEP--PADETPA-EARSPLSEETS--AEEAHAEVQSPLAEE--TTAEEASAEIQL 527

Query: 273 INESVDEADMENAGHPSADTPTATNYFLQYISSSLENSTNSADASSNKFVFGQNMSERVL 332
           +  +  EA       P+ +TP      L   +S+ E        S+      +   E  L
Sbjct: 528 L--AAIEA-------PADETPAEAQSPLSEETSAEEAPAEVQSPSAKGVSIEEAPLE--L 576

Query: 333 SPPKLNEVSSDANRENAAAESGSESSSQEATPE-KESLAESAAAYTKATARKCLLEKVEV 391
            PP   E +++         + +E+S++EA  E +   AE A A  +    +    +V+ 
Sbjct: 577 QPPSGEETTAEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQP 636

Query: 392 ITGEEAESNV 401
              EEA + V
Sbjct: 637 PPAEEAPAEV 646



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 45/188 (23%), Positives = 68/188 (36%), Gaps = 24/188 (12%)

Query: 8   EKPAIAPPVFVFQKDKGQKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGEHALEPPA 67
           E+ + A  +    +   +++PAE         +P    EAP      P       ++PP 
Sbjct: 587 EEASAAIQLLAATEASAEEAPAEV--------QPPPAEEAPAEVQPPPAEEAPAEVQPPP 638

Query: 68  PAGASASTPPPPAPE--AQLPPFPRELAGRSAGGSSPEGGEDSDREDGNY-CPPVKRERT 124
              A A   PPPA E  A++ P P E A        P   E++  E  +        E T
Sbjct: 639 AEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEV---QPPPAEEAPAEVQSLPAEETPIEET 695

Query: 125 SSLTQFPPSQ---SEERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRPAVLQAPQ 181
            +    PP+    +EE S      P  L+  +    G       E    V  P   Q P+
Sbjct: 696 LAAVHSPPADDVPAEEASVDKHSPPADLLLTEEFPIG-------EASAEVSPPPSEQTPE 748

Query: 182 PKALSQTV 189
            +AL + V
Sbjct: 749 DEALVENV 756



 Score = 31.6 bits (70), Expect = 2.0
 Identities = 45/173 (26%), Positives = 62/173 (35%), Gaps = 20/173 (11%)

Query: 7   EEKPAIA-PPVFVFQKDKGQKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGEHALEP 65
           EE PA   PP       + Q  PAE+   + +  +P    EAP      P       ++P
Sbjct: 604 EEAPAEVQPPPAEEAPAEVQPPPAEE---APAEVQPPPAEEAPAEVQPPPAEEAPAEVQP 660

Query: 66  PAPAGASASTPPPPAPEA-----QLPPFPRELAGRSAGGSSPEGGEDSDREDGN---YCP 117
           P    A A   PPPA EA      LP     +    A   SP   +D   E+ +   + P
Sbjct: 661 PPAEEAPAEVQPPPAEEAPAEVQSLPAEETPIEETLAAVHSPP-ADDVPAEEASVDKHSP 719

Query: 118 PVKRERTSSL------TQFPPSQSEERSSGFRLKPPTLIHGQAPS-AGLPSQK 163
           P     T          +  P  SE+      L        Q+P  AG+P+ K
Sbjct: 720 PADLLLTEEFPIGEASAEVSPPPSEQTPEDEALVENVSTEFQSPQVAGIPAVK 772


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 94/434 (21%), Positives = 153/434 (35%), Gaps = 74/434 (17%)

Query: 20  QKDKGQKSPAEQKNLSDSGEE-----PRGEAEAPHHGTGHP-----------ESAGEHAL 63
           ++++G++    ++  ++ GEE     P  EA +P      P           +S  +   
Sbjct: 479 KEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEA 538

Query: 64  EPPAPAGASASTPPPPAPEAQLPPF----PRELAGRSAGGSSPEGGEDSDREDG------ 113
           + PA   +      P   EA+ PP      +E A   A   SPE  +   +E+       
Sbjct: 539 KSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEA 598

Query: 114 ----NYCPPVKRERTSSLTQFPPSQSEERS-----SGFRLKPPTLIHGQAP-SAGLPSQK 163
                   PVK E  S      P + E +S     S  + K PT    ++P  A  P ++
Sbjct: 599 KSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKE 658

Query: 164 PKEQQRSVLRPAVLQAPQPKALSQTVPSSGTNGVSLPADCTGAVPAASPDTAAWRSPSEA 223
             +       P   +A  P+     V           A+      A SP     +SP +A
Sbjct: 659 EAKSPEKAKSPVKAEAKSPEKAKSPV----------KAEAKSPEKAKSPVKEEAKSPEKA 708

Query: 224 ADEVCALEEKEPQKNESSNASEEEACEK-KDPATQQAFVFGQNLRDRVKLINESVDEADM 282
              V   E K P+K +S    E +  EK K P  ++A        ++ K    S ++A  
Sbjct: 709 KSPV-KEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEA-----KSPEKAK----SPEKAKT 758

Query: 283 ENAGHPSADTP------TATNYFLQYISSSLENSTNSADASSNKFVFGQNMSERVLSPPK 336
            +   P A TP      +  + F +   S ++    S + + +         E+ +  PK
Sbjct: 759 LDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEI--PK 816

Query: 337 LNEVSSDANRENAAAE-------SGSESSSQEATPEKESLAES--AAAYTKATARKCLLE 387
             EV S    E    E         +E     ATP+ E   +S    A  K   +  + E
Sbjct: 817 KEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEE 876

Query: 388 KVEVITGEEAESNV 401
           K E    +  ES V
Sbjct: 877 KKEPAVEKPKESKV 890



 Score = 42.7 bits (99), Expect = 9e-04
 Identities = 53/258 (20%), Positives = 99/258 (38%), Gaps = 11/258 (4%)

Query: 8   EKPAIAPPVFVFQKDKGQKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGEHALEPPA 67
           ++ A +PP     + +  KSPAE K+   +    + EA++P       ++      E  +
Sbjct: 555 KEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKS 614

Query: 68  PAGASASTPPPPAPEAQLPPFPRELAGRSAGGSSPEGGEDSDREDG----NYCPPVKRER 123
           PA A +         A++    +  +       SPE  +  ++E+         PVK E 
Sbjct: 615 PAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEA 674

Query: 124 TSSLTQFPPSQSEERSSGFRLKPPTLIHGQAP-SAGLPSQKPKEQQRSVLRPAVLQAPQP 182
            S      P ++E +S   + K P     ++P  A  P ++  +       P   +A  P
Sbjct: 675 KSPEKAKSPVKAEAKSPE-KAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTP 733

Query: 183 KALSQTVPSSGTNGVSLPADCTGAVPAASPDTAAWRSPSEAADEVCALEEKEPQKNESSN 242
           +     V     +    P        A + D  +  + + A +E  +  +K P+K +S  
Sbjct: 734 EKAKSPVKEEAKS----PEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPV 789

Query: 243 ASEEEACEK-KDPATQQA 259
             E ++ EK K P  + A
Sbjct: 790 KEEVKSPEKAKSPLKEDA 807



 Score = 38.9 bits (89), Expect = 0.013
 Identities = 79/381 (20%), Positives = 134/381 (35%), Gaps = 43/381 (11%)

Query: 26  KSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGEHALEPPAPAGASASTPPPP-APEAQ 84
           KSPAE K+   +    + EA++P       +   +   E  +P  A + T     +PE  
Sbjct: 593 KSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKA 652

Query: 85  LPPFPRELAGRSAGGSSPEGGEDSDREDGNYCPPVKRERTSSLTQFPPSQSEERSSGFRL 144
             P  +E A       SP   E    E      PVK E  S      P + EE  S  + 
Sbjct: 653 KSP-EKEEAKSPEKAKSPVKAEAKSPEKAK--SPVKAEAKSPEKAKSPVK-EEAKSPEKA 708

Query: 145 KPPTLIHGQAPS---------AGLPSQKPKEQQRSVLRPAVLQAPQP-KALSQTVPSSGT 194
           K P     ++P          A  P +     +     P   ++P+  K L    P + T
Sbjct: 709 KSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKT 768

Query: 195 NGVSLPADCTGAVP--AASPDTAAWRSPSEAA----DEVCALEEKEPQKNESSNASEEE- 247
                        P  A SP     +SP +A     ++  A E++ P+K E  +  +EE 
Sbjct: 769 PAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEE 828

Query: 248 -------------ACEKKDPATQQAFVFGQNLRDRVKLINESVDEADMENAGHPSADTPT 294
                        A E+K PAT +      + ++      +   +  +E    P+ + P 
Sbjct: 829 KPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAP--KKEAPKPKVEEKKEPAVEKPK 886

Query: 295 ATNYFLQYISSSLENSTNSADASSNKFVFGQNMSERVLSPPK-LNEVSSDANRENAAAES 353
            +      + +  E + +     + +      +  +  + PK   EV+     +  A E 
Sbjct: 887 ESK-----VEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEP 941

Query: 354 GSESSSQEATPEKESLAESAA 374
              +  +EA PEK+   E  A
Sbjct: 942 SKPAEKKEAAPEKKDTKEEKA 962



 Score = 38.1 bits (87), Expect = 0.022
 Identities = 65/271 (23%), Positives = 97/271 (35%), Gaps = 52/271 (19%)

Query: 26  KSPA-EQKNLSDSGEEP-RGEAEAPHHGTGHPESAGEHALEPP---APAGASASTPPPPA 80
           KSP  E+    +  + P + EA++P      PE A    ++ P    PA   A +P    
Sbjct: 723 KSPVKEEAKTPEKAKSPVKEEAKSPEKAKS-PEKAKTLDVKSPEAKTPAKEEARSPADKF 781

Query: 81  PEAQLPPFPRELAGRSAGGSSPEGGEDSDREDGN-----------YCPPVKRERTSSLTQ 129
           PE    P   E+        SPE  +   +ED                PVK E      +
Sbjct: 782 PEKAKSPVKEEV-------KSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVK 834

Query: 130 F--PPSQSEERSSGFRLKPPTLIHG---QAPSAGLPSQKPKEQQRSVLRPAVLQAPQPKA 184
              PP ++EE  +    K          +AP    P  K +E++     PAV +  + K 
Sbjct: 835 VKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKE----PAVEKPKESKV 890

Query: 185 LSQTVPSSGTNGVSLPADCTGA---------------VPAASPDTAAWRSPSEAADEVCA 229
            ++   +     V  P     A               V    PD A  + PS+ A++  A
Sbjct: 891 EAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEA 950

Query: 230 LEEKEPQKNESSNASEE----EACEKKDPAT 256
             EK+  K E +   EE    EA  K+D  T
Sbjct: 951 APEKKDTKEEKAKKPEEKPKTEAKAKEDDKT 981


>gi|153070260 myristoylated alanine-rich protein kinase C substrate
           [Homo sapiens]
          Length = 332

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 62/241 (25%), Positives = 92/241 (38%), Gaps = 35/241 (14%)

Query: 21  KDKGQKSPAE-----QKNLSDSGEEPRGEAEAPH---HGTGHPESA--GEHALEPPAPAG 70
           K  G  SPA      ++ L  +G  P  + E P     G   P +A  GE A      AG
Sbjct: 40  KVNGDASPAAAESGAKEELQANGSAPAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAG 99

Query: 71  ASASTPPPPAP-EAQLPPFPRELAGRSAGG----SSPEGGEDSDREDGNYCPPVKRERTS 125
           AS      PA  EA  P  P    G +A      SSP+  + +     N  P  K++R S
Sbjct: 100 ASPVEKEAPAEGEAAEPGSPTAAEGEAASAASSTSSPKAEDGATPSPSNETPKKKKKRFS 159

Query: 126 SLTQFPPSQSEERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRPAVLQAPQPKAL 185
               F       + SGF  K      G+   A  P+ +  + + +    A        A 
Sbjct: 160 FKKSF-------KLSGFSFKKNKKEAGEGGEAEAPAAEGGKDEAAGGAAA--------AA 204

Query: 186 SQTVPSSGTNGVSLPADCTGAVPAASPDTAAWRSPSEAADEVCALEEKEPQKNESSNASE 245
           ++   +SG       A   G   AA  + AA   P EA  +  A+  ++P  ++ + A+E
Sbjct: 205 AEAGAASGEQ-----AAAPGEEAAAGEEGAAGGDPQEAKPQEAAVAPEKPPASDETKAAE 259

Query: 246 E 246
           E
Sbjct: 260 E 260


>gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithorax
           homolog, Drosophila); translocated to, 1 [Homo sapiens]
          Length = 559

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 68/291 (23%), Positives = 112/291 (38%), Gaps = 40/291 (13%)

Query: 48  PHHGTGHPESAGEHALEPPAPAGASASTPPPPAPEAQLPPFPRELAGRSAGGSSPEGGED 107
           P HG+   + A + + +   P   +      P  +++     +EL    A  S     +D
Sbjct: 177 PSHGS---KDANKESSKTSKPHKVTKEHRERPRKDSESKSSSKELEREQAKSS-----KD 228

Query: 108 SDREDGNYCPPVKRERTSSLTQFPPSQSEERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQ 167
           + R+ G    P K E+       PP ++  +     LK  T +   +P  G P   P   
Sbjct: 229 TSRKLGEGRLP-KEEKA------PPPKAAFKEPKMALKE-TKLESTSPKGGPPPPPPPPP 280

Query: 168 QRSVLRPAVLQAPQPKALSQTVPSS-----------GTNGVSLPADCTGAVPAASPDTAA 216
           + S  RPA   +P+P A  Q   SS            T+  S  +D   A   +S     
Sbjct: 281 RASSKRPATADSPKPSAKKQKKSSSKGSRSAPGTSPRTSSSSSFSDKKPAKDKSSTRGEK 340

Query: 217 WRSPSEAADEVCALEEKEPQ-------KNESSNASEEEACEKKDPATQQAFVFGQN---- 265
            ++ SE  +   ALE +E         K+ES+ +S   +    D ++   F   QN    
Sbjct: 341 VKAESEPREAKKALEVEESNSEDEASFKSESAQSSPSNSSSSSDSSSDSDFEPSQNHSQG 400

Query: 266 -LRDRVK-LINESVDEADMENAGHPSADTPTATNYFLQYISSSLENSTNSA 314
            LR  V+ L +E  DE D  +    +  T    +  L +  S  +NS +S+
Sbjct: 401 PLRSMVEDLQSEESDEDDSSSGEEAAGKTNPGRDSRLSFSDSESDNSADSS 451


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 64/268 (23%), Positives = 95/268 (35%), Gaps = 47/268 (17%)

Query: 10   PAIAPPVFVFQKDKGQKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGEHALEPPAPA 69
            PA  PP       KG  +P      S  G    G A  PH G  +P       + PP+P 
Sbjct: 1255 PATPPP-------KGAPTPPAATPPSLKG----GLATPPHKGAPNPA-----VVTPPSPK 1298

Query: 70   GASASTPP--PPAPEAQLPPFPRELAGR----------SAGGSSPEG-----GEDSDRED 112
            G  A++PP   P P A  PP P+   G           +    SP+G           + 
Sbjct: 1299 GGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKG 1358

Query: 113  GNYCPPVKRERTSSLTQFPPSQSEERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVL 172
            G   P  K   T      PP+ +     G  + PP+   G A    +PS K      +V+
Sbjct: 1359 GPTTPSSKEGPT------PPAATPSHKGGPAMTPPSPKRGPA----IPSPKGDPTSPAVI 1408

Query: 173  RPAVLQAPQPKALSQTVPSSGTNGVSLPADCTGAV---PAASPDTAAWRSPSEAADEVC- 228
              +  +AP      +   +     ++ PA    ++   PA S       +PS   D    
Sbjct: 1409 PLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLP 1468

Query: 229  ALEEKEPQKNESSNASEEEACEKKDPAT 256
            A+    P++  +       +  KK PAT
Sbjct: 1469 AVTPPSPKEPPAPKQVATSSSPKKAPAT 1496



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 55/230 (23%), Positives = 76/230 (33%), Gaps = 36/230 (15%)

Query: 9    KPAIAPPVFVFQKDKGQKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGEH---ALEP 65
            K A  PP       KG  +    K    +   P     +P  G   P   G     A+ P
Sbjct: 960  KWAPTPPAATPPSPKGGPATPSPKG---APTPPAATPPSPKGGPATPSPKGAPTPPAVTP 1016

Query: 66   PAPAGASASTPPP---PAPEAQLPPFPRELAGR-----------SAGGSSPEGGEDSDRE 111
            P+P G+ A+TP P     P A  PP P+                +A   SP+GG  +   
Sbjct: 1017 PSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSL 1076

Query: 112  DGNYCPPV---------KRERTSSLTQFPPSQSEERSSGFRLKPPTLIHGQAPSAGLPSQ 162
             G   PP              +      PP+ +     G    PP   H  AP+   P+ 
Sbjct: 1077 KGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPP---HKGAPTT--PAA 1131

Query: 163  KPKEQQRSVLRPAVLQAPQPKALSQTVPSSGTNGVSLPADCTGAVPAASP 212
             P   +  +  P    AP   A +   P  G    + P       PAA+P
Sbjct: 1132 TPPSPKGGLATPPPKGAPTTPAATPPSPKGGL--ATPPPKGAPTTPAATP 1179



 Score = 38.1 bits (87), Expect = 0.022
 Identities = 57/238 (23%), Positives = 84/238 (35%), Gaps = 51/238 (21%)

Query: 47   APHHGTGHPESAGEHAL---------EPPAPAGASASTPPPPAPE-----------AQLP 86
            AP  G   P S G+  L         EPPAP   + S+ P  AP            A +P
Sbjct: 1451 APKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIP 1510

Query: 87   PFPRELAGRSAGGSSPEGGED---SDREDGNYCP-------------PVKRERTSSLTQF 130
              P+E+    +    P        S +      P             P K     +  + 
Sbjct: 1511 SSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEA 1570

Query: 131  PPSQSEERSSGFRLKPPTLIHGQAPSA--GLPSQKPKEQQRSVLRPAVLQAPQPKALSQT 188
            P + S + +S     PP +     PS   G PS K      +V  P+  +AP P A++  
Sbjct: 1571 PATPSSKEASS----PPAV----TPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVT-- 1620

Query: 189  VPSSGTNGVSLPA-DCTGAVPAASPDTAAWRSPSEAADEVCALEEKEPQKNESSNASE 245
             P S   G + PA   T   P  +P +    SP+  A   C +    PQ ++   A +
Sbjct: 1621 -PPSPEKGPATPAPKGTPTSPPVTPSSLK-DSPTSPASVTCKMGATVPQASKGLPAKK 1676



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 57/220 (25%), Positives = 70/220 (31%), Gaps = 61/220 (27%)

Query: 10   PAIAPPVFVFQKDKGQKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGEH---ALEPP 66
            PA  PP       KG  +    K    +   P     +P  G   P   G     A  PP
Sbjct: 1198 PAATPP-----SPKGGLATPSPKGAPTT---PAATPPSPKGGLATPSPKGAPTTPAATPP 1249

Query: 67   APAGASASTPP--PPAPEAQLPPF--------PRELAGRSA--GGSSPEGGEDSDREDGN 114
            +P G  A+ PP   P P A  PP         P + A   A     SP+GG  +    G 
Sbjct: 1250 SPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGA 1309

Query: 115  YCPPVKRERTSSLTQFPPSQSEERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRP 174
              PP            PPS             P    G  P  G P+            P
Sbjct: 1310 PTPPAAT---------PPS-------------PKGSPGTPPPKGAPT------------P 1335

Query: 175  AVLQAPQPK---ALSQTVPSSGTNGVSLPADCTGAVPAAS 211
              +  P PK    L  T PSS   G + P+   G  P A+
Sbjct: 1336 PAVTPPSPKGTPTLPATTPSS-KGGPTTPSSKEGPTPPAA 1374



 Score = 35.0 bits (79), Expect = 0.18
 Identities = 51/206 (24%), Positives = 69/206 (33%), Gaps = 31/206 (15%)

Query: 27   SPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGEHALEPPAPAGA---SASTP------- 76
            SP E   L ++    +G  ++P         A  H+  PP+P GA   SA TP       
Sbjct: 829  SPVEASFLPENSLSFQGSKDSP---------ATTHSPTPPSPKGAPTPSAVTPLSPKGVT 879

Query: 77   -PP---PAPEAQLPPFPRELAGRSAGGSSPE-GGEDSDREDGNYCPPVKRERTSSLTQFP 131
             PP   P P     PFP+E     A   +P      S  +     P  K    S   +  
Sbjct: 880  LPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGA 939

Query: 132  PSQSEERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRPAVLQAPQPKALSQTVPS 191
            P+         +  P T     AP+   P+  P   +     P+   AP P A +   P 
Sbjct: 940  PTPPAATPPSPKGGPATPSPKWAPTP--PAATPPSPKGGPATPSPKGAPTPPAATPPSPK 997

Query: 192  SG-----TNGVSLPADCTGAVPAASP 212
             G       G   P   T   P  SP
Sbjct: 998  GGPATPSPKGAPTPPAVTPPSPKGSP 1023



 Score = 35.0 bits (79), Expect = 0.18
 Identities = 57/228 (25%), Positives = 80/228 (35%), Gaps = 30/228 (13%)

Query: 10   PAIAPPVFVFQKDKGQKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGEHALEPPAPA 69
            PA+ PP       KG  +       S  G       E P      P   G  A+ PP+P 
Sbjct: 1336 PAVTPP-----SPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPK 1390

Query: 70   GASASTPP--PPAPEAQLPPFPRELAGRSAGGSSPEGGEDSDREDGNYCPPV-------K 120
               A   P   P   A +P  P++     A   + EG     +  G+  PP        K
Sbjct: 1391 RGPAIPSPKGDPTSPAVIPLSPKK---APATPVTREGAATPSK--GDLTPPAVTPVSLKK 1445

Query: 121  RERTSSLTQFPPSQSEERSSGF-RLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRPAVLQA 179
               TS+    P + S +       + PP+     AP     S  PK   ++   PA + A
Sbjct: 1446 APATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPK---KAPATPAPMGA 1502

Query: 180  PQPKALSQTVPSSGTNGVSLPADCTGAV-PAA---SPDTAAWRSPSEA 223
            P    L   +PSS     + P+     + P A   S  T A  +P EA
Sbjct: 1503 P---TLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEA 1547



 Score = 33.1 bits (74), Expect = 0.70
 Identities = 54/218 (24%), Positives = 76/218 (34%), Gaps = 37/218 (16%)

Query: 10   PAIAPPVFVFQKDKGQKSPAEQ----------KNLSDSGEEPRGE-----AEAPHHGTGH 54
            PA+ PP      +KG  +PA +           +L DS   P        A  P    G 
Sbjct: 1617 PAVTPP----SPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGL 1672

Query: 55   PESAGEHALEPPAPAGASASTPPPPAPEAQLPPFPRELAGRSAGGSSPEGGEDSDREDGN 114
            P   G  AL+    A A  STP   AP  + P   +  A      +SP    D   ++G+
Sbjct: 1673 PAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSA------TSPPICPDPSAKNGS 1726

Query: 115  YCPPVKRERTSSLTQFPPSQSEERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRP 174
              P        S     P    ++ S    K     H    S   P   P+ +  + L  
Sbjct: 1727 KGP-------LSTVAPAPLLPVQKDSSKTAKGKDASH----SPKGPLAPPESKASTPLTA 1775

Query: 175  AVLQAPQPKALSQTVPSSGTNGVSLPADCTGAVPAASP 212
            A  +   PK  S +V ++ +  VSLP      VP   P
Sbjct: 1776 AAFEKVLPKPESASVSAAPSPPVSLPL-APSPVPTLPP 1812



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 58/214 (27%), Positives = 71/214 (33%), Gaps = 45/214 (21%)

Query: 43   GEAEAPHHGTGHPESAG----EHALEPPAPAGAS---ASTPPPP-----------AP--E 82
            G A  PH G     +A     +  L  P P GA    A+TPP P           AP   
Sbjct: 1116 GLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTP 1175

Query: 83   AQLPPFPR-ELAGRSAGGS---------SPEGGEDSDREDGNYCPPV---KRERTSSLTQ 129
            A  PP P+  LA  S  G+         SP+GG  +    G    P       +    T 
Sbjct: 1176 AATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATP 1235

Query: 130  FP------PSQSEERSSGFRLKPPTLIHGQAPSAGLPSQK---PKEQQRSVLRPAVLQAP 180
             P      P+ +     G    PP       P+A  PS K        +    PAV+  P
Sbjct: 1236 SPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPP 1295

Query: 181  QPKALSQTVPSSGTNGVSLPADCTGAVPAASPDT 214
             PK    T P     G   P   T   P  SP T
Sbjct: 1296 SPKGGPATSP---PKGAPTPPAATPPSPKGSPGT 1326


>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
          Length = 1427

 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 76/319 (23%), Positives = 112/319 (35%), Gaps = 44/319 (13%)

Query: 61   HALEPPAPAGASASTPPPPAPEAQLPPFPRELAGRSAGGSSPEGGEDSDREDGNYCPPVK 120
            HA E P  A    STP  PA  A   P P E    +A   +PE                 
Sbjct: 982  HAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPE----------------- 1024

Query: 121  RERTSSLTQFPPSQSEERSSGFRLKPPTLIHGQAPSAGLPS-QKPKEQQRSVLRPAVLQA 179
             E TS     PP    E  +      PT     +P+A +P+ ++P     +V  P    +
Sbjct: 1025 -EPTSPAAAVPP---PEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTS 1080

Query: 180  PQPKALSQTVPSSGTNGVSLPADCTGAVPAASPDTAAWRSPSEAADEVCALEEKEPQKNE 239
            P     +   P+S    V  P + T   PAA+  T     P E A    A+   E   + 
Sbjct: 1081 PAAAVPTPEEPTSPAAAVPTPEEPTS--PAAAVPT-----PEEPASPAAAVPTPEEPASP 1133

Query: 240  SSNASEEEACEKKDPATQQAFVFGQNLRDRVKLINESVDEADMENAGHPSADTPT-ATNY 298
            ++     E      PA               +  + +V     E +  P+A  PT A + 
Sbjct: 1134 AAAVPTPEEPAFPAPAVPTP----------EESASAAVAVPTPEESASPAAAVPTPAESA 1183

Query: 299  FLQYISSSLENSTNSADASSNKFVFGQNMSERVLSPPKLNEVSSDANRENAAAESGSE-- 356
                + ++LE  T+ A +          + E   + P  +  +S+     AAA S  E  
Sbjct: 1184 SFAAVVATLEEPTSPAASVPTPAAMVATLEE--FTSPAASVPTSEEPASLAAAVSNPEEP 1241

Query: 357  SSSQEATPEKESLAESAAA 375
            +S   A P  E    SAAA
Sbjct: 1242 TSPAAAVPTLEEPTSSAAA 1260



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 76/334 (22%), Positives = 119/334 (35%), Gaps = 37/334 (11%)

Query: 50   HGTGHPESAGEHALEPPAPAGASASTPPP--PAPEAQLPPFPRELAGRSAGGSSPEGGED 107
            H    P++A      P  PA  +A+ P P  P   A   P P E    +A    PE    
Sbjct: 982  HAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPE---- 1037

Query: 108  SDREDGNYCPPVKRERTSSLTQFPPSQSEERSSGFRLKPPTLIHGQAPSAGLPS-QKPKE 166
             +        P   E TS     P   + E  +      PT     +P+A +P+ ++P  
Sbjct: 1038 -EPTSPAAAVPTPEEPTSPAAAVP---TPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTS 1093

Query: 167  QQRSVLRPAVLQAPQPKALSQTVPSSGTNGVSLPAD-CTGAVPAASPDTAAWRSPSEAAD 225
               +V  P    +P     +   P+S    V  P +  + A    +P+  A+ +P+    
Sbjct: 1094 PAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTP 1153

Query: 226  E---VCALEEKEPQKNESSNASEEEACEKKDPATQQAFVFGQNLRDRVKLINESVDEADM 282
            E     A+    P+++ S  A+     E    A   A    +       +   +   A +
Sbjct: 1154 EESASAAVAVPTPEESASPAAAVPTPAESASFAAVVA-TLEEPTSPAASVPTPAAMVATL 1212

Query: 283  ENAGHPSADTPTATNYFLQYISSSLENSTNSADASSNKFVFGQNMSERVLSPPKLNEVSS 342
            E    P+A  PT+            E   + A A SN     +  +    + P L E +S
Sbjct: 1213 EEFTSPAASVPTS------------EEPASLAAAVSNP----EEPTSPAAAVPTLEEPTS 1256

Query: 343  DANRENAAAESGSESSSQEAT-PEKESLAESAAA 375
             A    AA  +  E SS  A+ P  E  A  AAA
Sbjct: 1257 SA----AAVLTPEELSSPAASVPTPEEPASPAAA 1286



 Score = 34.3 bits (77), Expect = 0.31
 Identities = 56/258 (21%), Positives = 85/258 (32%), Gaps = 41/258 (15%)

Query: 10   PAIAPPVFVFQKDKGQKSPAEQKNLSDSGEEPRGEAE-APHHGTGHPESAGEHALEPPAP 68
            PA A P            P  ++  S +   P  E   +P      PE     A   P P
Sbjct: 1068 PAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTP 1127

Query: 69   AGASASTPPPPAPEAQ-----LPPFPRELAGRSAG------GSSPEGGEDSDREDGNYCP 117
               ++     P PE         P P E A  +         +SP     +  E  ++  
Sbjct: 1128 EEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAA 1187

Query: 118  PVK--RERTSSLTQFP-------------------PSQSEERSSGFRLKPPTLIHGQAPS 156
             V    E TS     P                   P+  E  S    +  P      +P+
Sbjct: 1188 VVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPE--EPTSPA 1245

Query: 157  AGLPS-QKPKEQQRSVLRPAVLQAPQ---PKALSQTVPSSGTNGVSLPADCTGAVPAASP 212
            A +P+ ++P     +VL P  L +P    P       P++  + +  PA    AVP  +P
Sbjct: 1246 AAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVP--TP 1303

Query: 213  DTAAWRSPSEAADEVCAL 230
            + AA  + S    EV A+
Sbjct: 1304 EVAAIPAASVPTPEVPAI 1321


>gi|115648142 centrosomal protein 164kDa [Homo sapiens]
          Length = 1460

 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 84/374 (22%), Positives = 140/374 (37%), Gaps = 68/374 (18%)

Query: 38  GEEPRGEAEAPHHGTGHPESAG-EHALEPPAPAGASASTPPPPAPEAQLPPFPRELAGRS 96
           G E + ++++        +S G E  L PP P    A +PP      + PP   E  G+ 
Sbjct: 445 GIEDKDDSQSSQDELQSKQSKGLEERLSPPLPHEERAQSPPRSLATEEEPPQGPE--GQP 502

Query: 97  AGGSSPEGGEDSDREDGNYCPPVKRERTSSLTQFPPSQSEERSSGFRLKPPTLIHGQAPS 156
               + E GEDS                +SL+     Q E                QAPS
Sbjct: 503 EWKEAEELGEDS---------------AASLSLQLSLQRE----------------QAPS 531

Query: 157 AGLPSQKPKEQ--QRSVLRPAVLQAPQPK---ALSQTVPSSGTNGVSLPADCTGAVPAAS 211
                +K KEQ  Q   L P   +A  P+   A+S T P S         +     P A 
Sbjct: 532 PPAACEKGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVS--------PEVRSTEPVAP 583

Query: 212 PD---TAAWRSPSEAADEVCALEEKE--PQKNESSNASEEEACEKKDPATQQAFVFGQNL 266
           P+    AA ++  EA  +V   +++     K E      E+ C++++   ++     Q  
Sbjct: 584 PEQLSEAALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKLCQEEE---EEILRLHQQK 640

Query: 267 RDRVKLINESVDEADMENAGHPSADTPTATNYFLQYISSSLENSTNSADASSNKFVFGQN 326
              +  + E + +A  E      A      +  L ++ + +++ST + +         Q 
Sbjct: 641 EQSLSSLRERLQKAIEEE----EARMREEESQRLSWLRAQVQSSTQADE--------DQI 688

Query: 327 MSERVLSPPKL-NEVSSDANRENAAAESGSESSSQEATPEKESLAESAAAYTKATARKCL 385
            +E+  S  KL  E+ S    E A+ E  +    ++   E E+  +S  A   A   K L
Sbjct: 689 RAEQEASLQKLREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKAL 748

Query: 386 LEKVEVITGEEAES 399
            +  E + GE  E+
Sbjct: 749 QQLREQLEGERKEA 762


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 56/236 (23%), Positives = 72/236 (30%), Gaps = 45/236 (19%)

Query: 14  PPVFVFQKDKGQKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGEHALEPPAPAGASA 73
           PP     K +G   P + +     G++ R     P    G P   G     PP P G   
Sbjct: 81  PPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ 140

Query: 74  STPPPPAPEAQLPPFPRELAG-------RSAGGSSPEG------GEDSDREDGNYCPPVK 120
             PP    + Q PP P +  G       +S    SP G       +  ++  G   PP K
Sbjct: 141 GPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGK 200

Query: 121 RE-------------RTSSLTQFPPSQSEERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQ 167
            +                   Q PP Q + +S   R  PP    G  P  G   Q P   
Sbjct: 201 PQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSAR-SPPGKPQGPPPQGGNQPQGP--- 256

Query: 168 QRSVLRPAVLQAPQPKALSQTVPSSGTN---GVSLPADCTGAVPAASPDTAAWRSP 220
                       P P    Q  P  G N   G   P    G  P     + + RSP
Sbjct: 257 ------------PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSP 300



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 48/165 (29%), Positives = 56/165 (33%), Gaps = 35/165 (21%)

Query: 9   KPAIAPPVFVFQKDKGQKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGEHALEPPAP 68
           KP   PP       K Q  P +  + S S   P G+ + P      P   G     PP P
Sbjct: 273 KPQGPPP-----PGKPQGPPPQGGSKSRSSRSPPGKPQGP------PPQGGNQPQGPPPP 321

Query: 69  AGASASTPPPPAPEAQLPPFPRELAGRSAGGSSPEGGEDSDREDGNYCPPVKRERTSSLT 128
            G     PP    + Q PP P +       G  P+GG  S        PP K        
Sbjct: 322 PGKPQGPPPQGGNKPQGPPPPGK-----PQGPPPQGGSKSRSARS---PPGK-------P 366

Query: 129 QFPPSQSEERSSGFRLKPPTLIHG-----QAPSAGLPSQKPKEQQ 168
           Q PP Q      G    PP    G     QAP AG P   P+  Q
Sbjct: 367 QGPPQQEGNNPQG----PPPPAGGNPQQPQAPPAGQPQGPPRPPQ 407



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 55/215 (25%), Positives = 67/215 (31%), Gaps = 52/215 (24%)

Query: 38  GEEPRGEAEAPHHGTGHPESAGEHALEPPAPAGASASTP---------PPPAPEAQLPP- 87
           G +P+G    P    G P   G     PP P G     P         PPP  + Q PP 
Sbjct: 44  GNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPP 103

Query: 88  ------FPRELAGRSAGGSSPEGGEDSDREDGNYCPPVKRE-------------RTSSLT 128
                  PR   G+   G  P+GG   ++  G   PP K +                   
Sbjct: 104 QGDKSRSPRSPPGKPQ-GPPPQGG---NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKP 159

Query: 129 QFPPSQSEERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRPAVLQAPQPKALSQT 188
           Q PP Q + +S   R  PP    G  P  G   Q P               P P    Q 
Sbjct: 160 QGPPPQGDNKSRSSR-SPPGKPQGPPPQGGNQPQGP---------------PPPPGKPQG 203

Query: 189 VPSSGTN---GVSLPADCTGAVPAASPDTAAWRSP 220
            P  G N   G   P    G  P     + + RSP
Sbjct: 204 PPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSP 238



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 54/228 (23%), Positives = 71/228 (31%), Gaps = 30/228 (13%)

Query: 9   KPAIAPPVFVFQKDKGQKSPAEQKNLSDSGEEPRGEAEAP-----HHGTGHPESAGEHAL 63
           KP   PP       K Q  P +  N S S   P G+ + P     +   G P   G+   
Sbjct: 149 KPQGPPP-----PGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQG 203

Query: 64  EPPAPAGASASTPPPPAPEAQLPPFPRELAGRSAGGSSPEG--GEDSDREDGNYCPPVKR 121
            PP         PPP  P+   P    +     +    P+G   +  ++  G   PP K 
Sbjct: 204 PPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGK- 262

Query: 122 ERTSSLTQFPPSQSEERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRPAVLQA-- 179
                  Q PP Q   +  G    PP    G  P  G  S+  +        P       
Sbjct: 263 ------PQGPPPQGGNKPQG--PPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQ 314

Query: 180 ----PQPKALSQTVPSSGTN---GVSLPADCTGAVPAASPDTAAWRSP 220
               P P    Q  P  G N   G   P    G  P     + + RSP
Sbjct: 315 PQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSP 362



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 41/173 (23%), Positives = 62/173 (35%), Gaps = 19/173 (10%)

Query: 32  KNLSDSGEEPRGEAEAPHHGTGHPESAGEHALEPPAPAGASASTPPPPAPEAQLPPFP-- 89
           +NL++   +    +    +  G P   G     PP+P G     PP    + Q PP P  
Sbjct: 17  QNLNEDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPG 76

Query: 90  RELAGRSAGGSSPEGGEDSDREDGNYCPPVKRERTSS------LTQFPPSQSEERSSGFR 143
           +       GG+ P+G     +  G   PP + +++ S        Q PP Q   +  G  
Sbjct: 77  KPQGPPPQGGNKPQGPPPPGKPQG---PPPQGDKSRSPRSPPGKPQGPPPQGGNQPQG-P 132

Query: 144 LKPPTLIHGQAPSAGLPSQKPKEQQRSVLRPAVLQAPQPKALSQTVPSSGTNG 196
             PP    G  P  G   Q P         P   Q P P+  +++  S    G
Sbjct: 133 PPPPGKPQGPPPQGGNKPQGPPP-------PGKPQGPPPQGDNKSRSSRSPPG 178


>gi|91208418 transcription elongation regulator 1 isoform 2 [Homo
           sapiens]
          Length = 1077

 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 64/322 (19%), Positives = 111/322 (34%), Gaps = 31/322 (9%)

Query: 27  SPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGEHALEPPAPAGASASTPPPPAPEAQLP 86
           +P E +         RG A  P+     P       + PP P G     PPPP P    P
Sbjct: 15  NPGELRMAQQQALRFRGPAPPPNAVMRGPPPL----MRPPPPFGMMRGPPPPPRPPFGRP 70

Query: 87  PF-PRELAGRSAGGSSPEGGEDSDREDGNYCPPVKRERTSSLTQFPPSQSEERSSGFRLK 145
           PF P        GG  P  G    +      PP+          FPP      + G    
Sbjct: 71  PFDPNMPPMPPPGGIPPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPGMPPVTAPGTPAL 130

Query: 146 PPT---LIHGQAPSAGLPSQKPKEQQRSVLRPAVLQAPQPKALSQTVPSSGTNGVSLPAD 202
           PPT    +  + P   +     + ++ +  +P  ++  Q   L+  + +     V   A 
Sbjct: 131 PPTEEIWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQAQ--VQAQAQ 188

Query: 203 CTGAVPAASPDTAAWRSPSEAADEVCALEEKEPQKNESSNASEEEACEKKDPATQQAFVF 262
                 A +   A  ++ ++A  +  A  + + Q    + A  +   + +  A  QA V 
Sbjct: 189 AQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQ 248

Query: 263 GQNLRDRVKLINESVDEADMENAGHPSADTPTATNYFLQYISSSLENSTNSADASSNKFV 322
            Q              +A    A  P+  +P         +S+S  +ST S+  S+    
Sbjct: 249 AQ-------------VQAQAVGASTPTTSSPAPA------VSTSTSSSTPSSTTSTT--T 287

Query: 323 FGQNMSERVLSPPKLNEVSSDA 344
              ++++ V +P   ++  S A
Sbjct: 288 TATSVAQTVSTPTTQDQTPSSA 309


>gi|21327715 transcription elongation regulator 1 isoform 1 [Homo
           sapiens]
          Length = 1098

 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 64/322 (19%), Positives = 111/322 (34%), Gaps = 31/322 (9%)

Query: 27  SPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGEHALEPPAPAGASASTPPPPAPEAQLP 86
           +P E +         RG A  P+     P       + PP P G     PPPP P    P
Sbjct: 15  NPGELRMAQQQALRFRGPAPPPNAVMRGPPPL----MRPPPPFGMMRGPPPPPRPPFGRP 70

Query: 87  PF-PRELAGRSAGGSSPEGGEDSDREDGNYCPPVKRERTSSLTQFPPSQSEERSSGFRLK 145
           PF P        GG  P  G    +      PP+          FPP      + G    
Sbjct: 71  PFDPNMPPMPPPGGIPPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPGMPPVTAPGTPAL 130

Query: 146 PPT---LIHGQAPSAGLPSQKPKEQQRSVLRPAVLQAPQPKALSQTVPSSGTNGVSLPAD 202
           PPT    +  + P   +     + ++ +  +P  ++  Q   L+  + +     V   A 
Sbjct: 131 PPTEEIWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQAQ--VQAQAQ 188

Query: 203 CTGAVPAASPDTAAWRSPSEAADEVCALEEKEPQKNESSNASEEEACEKKDPATQQAFVF 262
                 A +   A  ++ ++A  +  A  + + Q    + A  +   + +  A  QA V 
Sbjct: 189 AQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQ 248

Query: 263 GQNLRDRVKLINESVDEADMENAGHPSADTPTATNYFLQYISSSLENSTNSADASSNKFV 322
            Q              +A    A  P+  +P         +S+S  +ST S+  S+    
Sbjct: 249 AQ-------------VQAQAVGASTPTTSSPAPA------VSTSTSSSTPSSTTSTT--T 287

Query: 323 FGQNMSERVLSPPKLNEVSSDA 344
              ++++ V +P   ++  S A
Sbjct: 288 TATSVAQTVSTPTTQDQTPSSA 309


>gi|221307607 RANBP2-like and GRIP domain containing 3 [Homo sapiens]
          Length = 1758

 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 33/111 (29%), Positives = 57/111 (51%), Gaps = 6/111 (5%)

Query: 387  EKVEVITGEEAESNVLQMQCKLFVFDKTSQSWVERGRGLLRLNDMASTDDGTLQSRLVMR 446
            EKVE++TGEE E  +     KLF FD     W ERG G L++  + +  +G +  R++M+
Sbjct: 1046 EKVELVTGEEGEKVLYSQGVKLFRFDAEVSQWKERGLGNLKI--LKNEVNGKV--RMLMQ 1101

Query: 447  TQGSLRLILNTKLWAQMQID--KASEKSIRITAMDTEDQGVKVFLISASSK 495
             +  L++  N  +   M +     S+++   +A D  D   K+  ++A  K
Sbjct: 1102 REQVLKVCANHWITTTMNLKPLSGSDRAWMWSASDFSDGDAKLERLAAKFK 1152



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 55/224 (24%), Positives = 96/224 (42%), Gaps = 36/224 (16%)

Query: 268  DRVKLINESVDEADMENAGH--PSADTPTATNYFLQYISSSLENSTNSADASSNKFVFGQ 325
            D   L  +++D++   ++ H  P A +P   N F         +   S   S+  F    
Sbjct: 1250 DNYDLREDALDDSVSSSSVHASPLASSPVRKNLF---------HFDESTTGSNFSFKSAL 1300

Query: 326  NMSERVLSPPKLNEVSSDANRENAAAESGSESSSQEATPEKESLAESAAAYTKATARKCL 385
            ++S+   SP KLN+  +           G++  S + T E+E   +             L
Sbjct: 1301 SLSK---SPAKLNQSGTSV---------GTDEES-DVTQEEERDGQYFEPVVP------L 1341

Query: 386  LEKVEVITGEEAESNVLQMQCKLFVFDKTSQSWVERGRGLLRLNDMASTDDGTLQSRLVM 445
             + VEV +GEE E  V   + + + +DK    W ERG G +++  + + D+  +  R++M
Sbjct: 1342 PDLVEVSSGEENEQVVFSHRAEFYRYDKDVGQWKERGIGDIKI--LQNYDNKHV--RILM 1397

Query: 446  RTQGSLRLILNTKLWAQMQID--KASEKSIRITAMDTEDQGVKV 487
            R    L+L  N ++   M +   K +E+    TA D  D   KV
Sbjct: 1398 RRDQVLKLCANHRITPDMSLQNMKGTERVWVWTACDFADGERKV 1441



 Score = 30.4 bits (67), Expect = 4.5
 Identities = 20/84 (23%), Positives = 35/84 (41%)

Query: 305  SSLENSTNSADASSNKFVFGQNMSERVLSPPKLNEVSSDANRENAAAESGSESSSQEATP 364
            SS   +T  A  S  KFVFG    +R+ S  K    +   +    +    S ++  ++  
Sbjct: 1523 SSTSETTTKAVVSPPKFVFGSESVKRIFSSEKSKPFAFGNSSATGSLFGFSFNAPLKSNN 1582

Query: 365  EKESLAESAAAYTKATARKCLLEK 388
             + S    + + +K   +KC L K
Sbjct: 1583 SETSSVAQSGSESKVEPKKCELSK 1606


>gi|239747210 PREDICTED: hypothetical protein XP_002346689 [Homo
           sapiens]
          Length = 275

 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 45/177 (25%), Positives = 69/177 (38%), Gaps = 13/177 (7%)

Query: 8   EKPAIAPPVFVFQKDKGQKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGEHALE--- 64
           +K +  P     Q D+G   PAE     D G  P  E +       HP +  +  ++   
Sbjct: 32  DKGSCPPAELDRQMDRGSHPPAELDGQMDRGSRPPAELDGQMDRGSHPPAELDGQMDGGS 91

Query: 65  -PPAPAGA--SASTPPPPAPEAQLPPF---PRELAGRSAGGSSPEGGEDSDREDGNYCPP 118
            PPA         + PP   + Q+      P EL G+  GGS P    D  + DG   PP
Sbjct: 92  RPPAELDGQMDGGSRPPGELDGQMDGGSRPPAELDGQMDGGSRPPAELDG-QMDGGSRPP 150

Query: 119 VKRERTSSLTQFPPSQSE-ERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRP 174
            + +        PP++ + +  +G R  PP  + GQ  +   P  +   Q  +  RP
Sbjct: 151 AELDGQMDTGSRPPAELDGQMDTGSR--PPAELDGQMDTGSRPPAELDGQTDTGSRP 205



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 45/175 (25%), Positives = 69/175 (39%), Gaps = 20/175 (11%)

Query: 20  QKDKGQKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGEHALE----PPAPAGA--SA 73
           Q D G + PAE     D G  P GE +    G   P +  +  ++    PPA        
Sbjct: 86  QMDGGSRPPAELDGQMDGGSRPPGELDGQMDGGSRPPAELDGQMDGGSRPPAELDGQMDG 145

Query: 74  STPPPPAPEAQLPPF---PRELAGRSAGGSSPEGGEDSDREDGNYCPPVKRERTSSLTQF 130
            + PP   + Q+      P EL G+   GS P    D   + G+  PP + +  +     
Sbjct: 146 GSRPPAELDGQMDTGSRPPAELDGQMDTGSRPPAELDGQMDTGSR-PPAELDGQTDTGSR 204

Query: 131 PPSQSE---ERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRPAVLQAPQP 182
           PP++ +   +R S    +PP  + GQ  +   P   P E    +  P +LQ   P
Sbjct: 205 PPAELDGQMDRGS----RPPAELDGQMDTGSRP---PAELALPMPPPEMLQLGAP 252



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 41/165 (24%), Positives = 64/165 (38%), Gaps = 13/165 (7%)

Query: 20  QKDKGQKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGEHALE----PPAPAGA--SA 73
           Q D+G + PAE     D G  P  E +    G   P +  +  ++    PP         
Sbjct: 58  QMDRGSRPPAELDGQMDRGSHPPAELDGQMDGGSRPPAELDGQMDGGSRPPGELDGQMDG 117

Query: 74  STPPPPAPEAQLPPF---PRELAGRSAGGSSPEGGEDSDREDGNYCPPVKRERTSSLTQF 130
            + PP   + Q+      P EL G+  GGS P    D   + G+  PP + +        
Sbjct: 118 GSRPPAELDGQMDGGSRPPAELDGQMDGGSRPPAELDGQMDTGSR-PPAELDGQMDTGSR 176

Query: 131 PPSQSE-ERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRP 174
           PP++ + +  +G R  PP  + GQ  +   P  +   Q     RP
Sbjct: 177 PPAELDGQMDTGSR--PPAELDGQTDTGSRPPAELDGQMDRGSRP 219


>gi|157266273 RANBP2-like and GRIP domain containing 1 [Homo sapiens]
          Length = 1756

 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 34/111 (30%), Positives = 55/111 (49%), Gaps = 6/111 (5%)

Query: 387  EKVEVITGEEAESNVLQMQCKLFVFDKTSQSWVERGRGLLRLNDMASTDDGTLQSRLVMR 446
            EKVE++TGEE E  +     KLF FD     W ERG G L++  + +  +G  + R++MR
Sbjct: 1038 EKVELVTGEEGEKVLYSQGVKLFRFDAEISQWKERGLGNLKI--LKNEVNG--KPRMLMR 1093

Query: 447  TQGSLRLILNTKLWAQMQID--KASEKSIRITAMDTEDQGVKVFLISASSK 495
                L++  N  +   M +     S+++    A D  D   K+  ++A  K
Sbjct: 1094 RDQVLKVCANHWITTTMNLKPLSGSDRAWMWLASDFSDGDAKLERLAAQFK 1144



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 63/258 (24%), Positives = 110/258 (42%), Gaps = 36/258 (13%)

Query: 232  EKEPQKNESSNASEEEACEKKDPATQQAFVFGQNLRDRVKLINESVDEADMENAGHPSAD 291
            E+E + + +  A   +   K +P      +   N   R   ++++V  + + ++  P A 
Sbjct: 1210 EEENKGSGTGAAGASDTTIKPNPENTGPTLEWDNYDLREDALDDNVSSSSVHDS--PLAS 1267

Query: 292  TPTATNYFLQYISSSLENSTNSADASSNKFVFGQNMSERVLSPPKLNEVSSDANRENAAA 351
            +P   N F        + ST   + S   F    ++S+   SP KLN+  +         
Sbjct: 1268 SPVRKNIF------RFDESTTGFNFS---FKSALSLSK---SPAKLNQSGTSV------- 1308

Query: 352  ESGSESSSQEATPEKESLAESAAAYTKATARKCLLEKVEVITGEEAESNVLQMQCKLFVF 411
              G++  S + T E+E   +             L + VEV +GEE E  V   + +L+ +
Sbjct: 1309 --GTDEES-DVTQEEERDGQYFEPVVP------LPDLVEVSSGEENEQVVFSHRAELYRY 1359

Query: 412  DKTSQSWVERGRGLLRLNDMASTDDGTLQSRLVMRTQGSLRLILNTKLWAQMQID--KAS 469
            DK    W ERG G +++  + + D+   Q R+VMR    L+L  N ++   M +   K +
Sbjct: 1360 DKDVGQWKERGIGDIKI--LQNYDN--KQVRIVMRRDQVLKLCANHRITPDMSLQNMKGT 1415

Query: 470  EKSIRITAMDTEDQGVKV 487
            E+    TA D  D   KV
Sbjct: 1416 ERVWVWTACDFADGERKV 1433



 Score = 33.1 bits (74), Expect = 0.70
 Identities = 21/84 (25%), Positives = 36/84 (42%)

Query: 305  SSLENSTNSADASSNKFVFGQNMSERVLSPPKLNEVSSDANRENAAAESGSESSSQEATP 364
            SS   +T  A  S  KFVFG    +R+ S  K N  +   +    +    S ++  ++  
Sbjct: 1515 SSTSETTTKAVVSPPKFVFGSESVKRIFSSEKSNPFAFGNSSATGSLFGFSFNAPLKSND 1574

Query: 365  EKESLAESAAAYTKATARKCLLEK 388
             + S    + + +K   +KC L K
Sbjct: 1575 SETSSVAQSGSESKVEPKKCELSK 1598


>gi|118200331 RANBP2-like and GRIP domain containing 2 [Homo
           sapiens]
          Length = 1013

 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 34/111 (30%), Positives = 55/111 (49%), Gaps = 6/111 (5%)

Query: 387 EKVEVITGEEAESNVLQMQCKLFVFDKTSQSWVERGRGLLRLNDMASTDDGTLQSRLVMR 446
           EKVE++TGEE E  +     KLF FD     W ERG G L++  + +  +G  + R++MR
Sbjct: 295 EKVELVTGEEGEKVLYSQGVKLFRFDAEISQWKERGLGNLKI--LKNEVNG--KPRMLMR 350

Query: 447 TQGSLRLILNTKLWAQMQID--KASEKSIRITAMDTEDQGVKVFLISASSK 495
               L++  N  +   M +     S+++    A D  D   K+  ++A  K
Sbjct: 351 RDQVLKVCANHWITTTMNLKPLSGSDRAWMWLASDFSDGDAKLERLAAQFK 401



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 63/258 (24%), Positives = 109/258 (42%), Gaps = 36/258 (13%)

Query: 232 EKEPQKNESSNASEEEACEKKDPATQQAFVFGQNLRDRVKLINESVDEADMENAGHPSAD 291
           E+E + + +  A   +   K +P      +   N   R   ++++V  + + ++  P A 
Sbjct: 467 EEENKGSGTGAAGASDTTIKPNPENTGPTLEWDNYDLREDALDDNVSSSSVHDS--PLAS 524

Query: 292 TPTATNYFLQYISSSLENSTNSADASSNKFVFGQNMSERVLSPPKLNEVSSDANRENAAA 351
           +P   N F        + ST   + S   F    ++S+   SP KLN+  +         
Sbjct: 525 SPVRKNIF------RFDESTTGFNFS---FKSALSLSK---SPAKLNQSGTSV------- 565

Query: 352 ESGSESSSQEATPEKESLAESAAAYTKATARKCLLEKVEVITGEEAESNVLQMQCKLFVF 411
             G++  S + T E+E   +             L + VEV +GEE E  V     +L+ +
Sbjct: 566 --GTDEES-DVTQEEERDGQYFEPVVP------LPDLVEVSSGEENEQVVFSHMAELYRY 616

Query: 412 DKTSQSWVERGRGLLRLNDMASTDDGTLQSRLVMRTQGSLRLILNTKLWAQMQID--KAS 469
           DK    W ERG G +++  + + D+   Q R+VMR    L+L  N ++   M +   K +
Sbjct: 617 DKDVGQWKERGIGDIKI--LQNYDN--KQVRIVMRRDQVLKLCANHRITPDMSLQNMKGT 672

Query: 470 EKSIRITAMDTEDQGVKV 487
           E+    TA D  D   KV
Sbjct: 673 ERVWVWTACDFADGERKV 690



 Score = 33.1 bits (74), Expect = 0.70
 Identities = 21/84 (25%), Positives = 36/84 (42%)

Query: 305 SSLENSTNSADASSNKFVFGQNMSERVLSPPKLNEVSSDANRENAAAESGSESSSQEATP 364
           SS   +T  A  S  KFVFG    +R+ S  K N  +   +    +    S ++  ++  
Sbjct: 772 SSTSETTTKAVVSPPKFVFGSESVKRIFSSEKSNPFAFGNSSATGSLFGFSFNAPLKSND 831

Query: 365 EKESLAESAAAYTKATARKCLLEK 388
            + S    + + +K   +KC L K
Sbjct: 832 SETSSVAQSGSESKVEPKKCELSK 855


>gi|211059431 RANBP2-like and GRIP domain containing 4 [Homo sapiens]
          Length = 1758

 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 33/111 (29%), Positives = 57/111 (51%), Gaps = 6/111 (5%)

Query: 387  EKVEVITGEEAESNVLQMQCKLFVFDKTSQSWVERGRGLLRLNDMASTDDGTLQSRLVMR 446
            EKVE++ GEE E  +     KLF FD   + W ERG G L++  + +  +G  + R++MR
Sbjct: 1046 EKVELVIGEEGEKVLYSQGVKLFRFDAEVRQWKERGLGNLKI--LKNEVNG--KPRMLMR 1101

Query: 447  TQGSLRLILNTKLWAQMQID--KASEKSIRITAMDTEDQGVKVFLISASSK 495
             +  L++  N  +   M +     S+++   +A D  D   K+  ++A  K
Sbjct: 1102 REQVLKVCANHWITTTMNLKPLSGSDRAWMWSASDFSDGDAKLERLAAKFK 1152



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 63/258 (24%), Positives = 107/258 (41%), Gaps = 36/258 (13%)

Query: 232  EKEPQKNESSNASEEEACEKKDPATQQAFVFGQNLRDRVKLINESVDEADMENAGHPSAD 291
            E+E + + +  A   +   K +P      +   N   R   +++SV  + +  +  P A 
Sbjct: 1218 EEENKGSGTGAAGASDTTIKPNPENTGPTLEWDNCDLREDALDDSVSSSSVHAS--PLAS 1275

Query: 292  TPTATNYFLQYISSSLENSTNSADASSNKFVFGQNMSERVLSPPKLNEVSSDANRENAAA 351
            +P   N F    S++  N +  +  S +K            SP KLN+  +         
Sbjct: 1276 SPVRKNLFHFGESTTGSNFSFKSALSPSK------------SPAKLNQSGTSV------- 1316

Query: 352  ESGSESSSQEATPEKESLAESAAAYTKATARKCLLEKVEVITGEEAESNVLQMQCKLFVF 411
              G++  S + T E+E   +             L + VEV +GEE E  V   + +L+ +
Sbjct: 1317 --GTDEES-DVTQEEERDGQYFEPVVP------LPDLVEVSSGEENEKVVFSHRAELYRY 1367

Query: 412  DKTSQSWVERGRGLLRLNDMASTDDGTLQSRLVMRTQGSLRLILNTKLWAQMQID--KAS 469
            DK    W ERG G +++  + + D+   Q R+VMR    L+L  N  +   M +   K +
Sbjct: 1368 DKDVGQWKERGIGDIKI--LQNYDN--KQVRIVMRRDQVLKLCANHTITPDMSLQNMKGT 1423

Query: 470  EKSIRITAMDTEDQGVKV 487
            E+    TA D  D   KV
Sbjct: 1424 ERVWVWTACDFADGERKV 1441



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 21/84 (25%), Positives = 36/84 (42%)

Query: 305  SSLENSTNSADASSNKFVFGQNMSERVLSPPKLNEVSSDANRENAAAESGSESSSQEATP 364
            SS   +T  A  S  KFVFG    +R+ S  K    +   +    +    S ++S ++  
Sbjct: 1523 SSTSETTTKAVVSPPKFVFGSESVKRIFSSEKSKPFAFGNSSATGSLFGFSFNASLKSNN 1582

Query: 365  EKESLAESAAAYTKATARKCLLEK 388
             + S    + + +K   +KC L K
Sbjct: 1583 SETSSVAQSGSESKVEPKKCELSK 1606


>gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Homo
           sapiens]
          Length = 247

 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 55/207 (26%), Positives = 68/207 (32%), Gaps = 31/207 (14%)

Query: 38  GEEPRGEAEAPHHGTGHPESAGEHALEPPAPAGASASTPPP-------PAPEAQLPPFPR 90
           G +P+     P    G P   G  +  PP P G     PP        P P    P  P 
Sbjct: 44  GNQPQRPPPPPGKPQGPPPQGGNQSQGPPPPPGKPEGRPPQGGNQSQGPPPHPGKPERPP 103

Query: 91  ELAGRSAGGSSPEGG--EDSDREDGNYC-----PPVKRERTSSLTQFPPSQSEERSS--- 140
              G  + G+ P  G  E    + GN       PP K ER       PP Q   +S    
Sbjct: 104 PQGGNQSQGTPPPPGKPERPPPQGGNQSHRPPPPPGKPER-------PPPQGGNQSQGPP 156

Query: 141 ---GFRLKPPTLIHGQAPSAGLPSQKPK-EQQRSVLRPAVLQAPQPKALSQTVPSSGTNG 196
              G    PP     ++ SA  P  KP+   Q+   +P   Q P P    Q  P +G N 
Sbjct: 157 PHPGKPEGPPPQEGNKSRSARSPPGKPQGPPQQEGNKP---QGPPPPGKPQGPPPAGGNP 213

Query: 197 VSLPADCTGAVPAASPDTAAWRSPSEA 223
               A   G      P     R P  A
Sbjct: 214 QQPQAPPAGKPQGPPPPPQGGRPPRPA 240



 Score = 38.5 bits (88), Expect = 0.017
 Identities = 44/165 (26%), Positives = 57/165 (34%), Gaps = 34/165 (20%)

Query: 35  SDSGEEPRGEAEAPHHGTGHPES----AGEHALEPPAPAGASASTPPPPAPEAQLPPFPR 90
           ++S  E   + E+    +G PE      G     PP P G     PP    ++Q PP P 
Sbjct: 16  AESSSEDVSQEESLFLISGKPEGRRPQGGNQPQRPPPPPGKPQGPPPQGGNQSQGPPPP- 74

Query: 91  ELAGRSAGGSSPEGGEDSDREDGNYCPPVKRERTSSLTQFPPSQSEERSSGFRLKPPTLI 150
              G+   G  P+GG  S    G    P K ER       PP Q   +S           
Sbjct: 75  --PGKPE-GRPPQGGNQS---QGPPPHPGKPER-------PPPQGGNQS----------- 110

Query: 151 HGQAPSAGLPSQKPKEQQRSVLRPAVLQAPQPKALSQTVPSSGTN 195
            G  P  G P + P +      RP     P P    +  P  G N
Sbjct: 111 QGTPPPPGKPERPPPQGGNQSHRP-----PPPPGKPERPPPQGGN 150



 Score = 34.3 bits (77), Expect = 0.31
 Identities = 24/86 (27%), Positives = 37/86 (43%), Gaps = 15/86 (17%)

Query: 6   NEEKPAIAPPVFVFQKDKGQKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGEHALEP 65
           N+ + A +PP     K +G   P +Q+     G  P G+ + P    G+P+       +P
Sbjct: 171 NKSRSARSPP----GKPQG---PPQQEGNKPQGPPPPGKPQGPPPAGGNPQ-------QP 216

Query: 66  PAPAGASASTPPPPAPEAQLPPFPRE 91
            AP       PPPP    + PP P +
Sbjct: 217 QAPPAGKPQGPPPPPQGGR-PPRPAQ 241


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.305    0.122    0.340 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,628,818
Number of Sequences: 37866
Number of extensions: 1508084
Number of successful extensions: 14875
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 192
Number of HSP's successfully gapped in prelim test: 993
Number of HSP's that attempted gapping in prelim test: 10076
Number of HSP's gapped (non-prelim): 4339
length of query: 567
length of database: 18,247,518
effective HSP length: 108
effective length of query: 459
effective length of database: 14,157,990
effective search space: 6498517410
effective search space used: 6498517410
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.