BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|63054864 phosphoprotein associated with glycosphingolipid microdomains 1 [Homo sapiens] (432 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|63054864 phosphoprotein associated with glycosphingolipid mic... 863 0.0 gi|146229340 mutated in colorectal cancers isoform 1 [Homo sapiens] 40 0.004 gi|150170670 piccolo isoform 2 [Homo sapiens] 39 0.007 gi|150378539 piccolo isoform 1 [Homo sapiens] 39 0.007 gi|55741677 SET domain containing 1A [Homo sapiens] 39 0.012 gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 39 0.012 gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 38 0.016 gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 38 0.016 gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 38 0.016 gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 38 0.016 gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 38 0.016 gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 37 0.027 gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 37 0.027 gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 37 0.027 gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 37 0.027 gi|38372901 Sp1 transcription factor isoform a [Homo sapiens] 37 0.035 gi|218751903 Sp1 transcription factor isoform b [Homo sapiens] 37 0.035 gi|4505129 mutated in colorectal cancers isoform 2 [Homo sapiens] 37 0.035 gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 37 0.045 gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 37 0.045 gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isof... 37 0.045 gi|23111062 splicing factor, arginine/serine-rich 8 [Homo sapiens] 36 0.059 gi|113415504 PREDICTED: similar to ribonucleic acid binding prot... 36 0.078 gi|169166499 PREDICTED: similar to ribonucleic acid binding prot... 36 0.078 gi|113415498 PREDICTED: similar to ribonucleic acid binding prot... 36 0.078 gi|88973230 PREDICTED: similar to ribonucleic acid binding prote... 36 0.078 gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 36 0.078 gi|23111036 sorting nexin 1 isoform c [Homo sapiens] 35 0.10 gi|23111034 sorting nexin 1 isoform a [Homo sapiens] 35 0.10 gi|42518068 trans-golgi network protein 2 [Homo sapiens] 35 0.10 >gi|63054864 phosphoprotein associated with glycosphingolipid microdomains 1 [Homo sapiens] Length = 432 Score = 863 bits (2229), Expect = 0.0 Identities = 432/432 (100%), Positives = 432/432 (100%) Query: 1 MGPAGSLLGSGQMQITLWGSLAAVAIFFVITFLIFLCSSCDREKKPRQHSGDHENLMNVP 60 MGPAGSLLGSGQMQITLWGSLAAVAIFFVITFLIFLCSSCDREKKPRQHSGDHENLMNVP Sbjct: 1 MGPAGSLLGSGQMQITLWGSLAAVAIFFVITFLIFLCSSCDREKKPRQHSGDHENLMNVP 60 Query: 61 SDKEMFSRSVTSLATDAPASSEQNGALTNGDILSEDSTLTCMQHYEEVQTSASDLLDSQD 120 SDKEMFSRSVTSLATDAPASSEQNGALTNGDILSEDSTLTCMQHYEEVQTSASDLLDSQD Sbjct: 61 SDKEMFSRSVTSLATDAPASSEQNGALTNGDILSEDSTLTCMQHYEEVQTSASDLLDSQD 120 Query: 121 STGKPKCHQSRELPRIPPESAVDTMLTARSVDGDQGLGMEGPYEVLKDSSSQENMVEDCL 180 STGKPKCHQSRELPRIPPESAVDTMLTARSVDGDQGLGMEGPYEVLKDSSSQENMVEDCL Sbjct: 121 STGKPKCHQSRELPRIPPESAVDTMLTARSVDGDQGLGMEGPYEVLKDSSSQENMVEDCL 180 Query: 181 YETVKEIKEVAAAAHLEKGHSGKAKSTSASKELPGPQTEGKAEFAEYASVDRNKKCRQSV 240 YETVKEIKEVAAAAHLEKGHSGKAKSTSASKELPGPQTEGKAEFAEYASVDRNKKCRQSV Sbjct: 181 YETVKEIKEVAAAAHLEKGHSGKAKSTSASKELPGPQTEGKAEFAEYASVDRNKKCRQSV 240 Query: 241 NVESILGNSCDPEEEAPPPVPVKLLDENENLQEKEGGEAEESATDTTSETNKRFSSLSYK 300 NVESILGNSCDPEEEAPPPVPVKLLDENENLQEKEGGEAEESATDTTSETNKRFSSLSYK Sbjct: 241 NVESILGNSCDPEEEAPPPVPVKLLDENENLQEKEGGEAEESATDTTSETNKRFSSLSYK 300 Query: 301 SREEDPTLTEEEISAMYSSVNKPGQLVNKSGQSLTVPESTYTSIQGDPQRSPSSCNDLYA 360 SREEDPTLTEEEISAMYSSVNKPGQLVNKSGQSLTVPESTYTSIQGDPQRSPSSCNDLYA Sbjct: 301 SREEDPTLTEEEISAMYSSVNKPGQLVNKSGQSLTVPESTYTSIQGDPQRSPSSCNDLYA 360 Query: 361 TVKDFEKTPNSTLPPAGRPSEEPEPDYEAIQTLNREEEKATLGTNGHHGLVPKENDYESI 420 TVKDFEKTPNSTLPPAGRPSEEPEPDYEAIQTLNREEEKATLGTNGHHGLVPKENDYESI Sbjct: 361 TVKDFEKTPNSTLPPAGRPSEEPEPDYEAIQTLNREEEKATLGTNGHHGLVPKENDYESI 420 Query: 421 SDLQQGRDITRL 432 SDLQQGRDITRL Sbjct: 421 SDLQQGRDITRL 432 >gi|146229340 mutated in colorectal cancers isoform 1 [Homo sapiens] Length = 1019 Score = 40.0 bits (92), Expect = 0.004 Identities = 65/284 (22%), Positives = 110/284 (38%), Gaps = 22/284 (7%) Query: 83 QNGALTNGDILSEDSTLTCMQHYEEVQTSASDLLDSQDSTGKPKCHQSRELPRIPPESAV 142 Q GA NG I +D T MQ E++ DL D++ K ++++ Sbjct: 79 QLGADENGKISFQDFTRCRMQLVREIRKEEVDLSAKSDNSCTKKLRDRIASWPTSSDNSL 138 Query: 143 DTMLTAR-SVDGDQGLGMEGPYEVLKDSSSQENMVEDCLYETVKEIKEVAAAAHLEKGHS 201 + AR S + D G +V S+ Q+ L E AA H S Sbjct: 139 GALSAARESWEYDSGARDLQSPDVQSQSALQK------LLEYGGSSLHQQAALHKLLTQS 192 Query: 202 GKAKSTSASKELPGPQTEGKAEFAEYAS--VDRNKKCRQSVNVESILGNSCDPEEEAPPP 259 ++ L T A A V+ NK+ +Q+ +L + Sbjct: 193 PHIGNSVGGSYLELANTLHSAALASLKGDIVELNKRLQQTERERDLLEKKLAKAQCEQS- 251 Query: 260 VPVKLLDENENLQEKEGGEAEESATDTTS---ETNKRFSSLSYKSREEDPTLTE--EEIS 314 L+ E+E++QE+ EE T+ S E NK+ L + E+ +E E+S Sbjct: 252 ---HLMREHEDVQERTTLRYEERITELHSVIAELNKKIDRLQGTTIREEDEYSELRSELS 308 Query: 315 AMYSSVNKPGQLVNKSGQSLTVPESTYTSIQGDPQRSPSSCNDL 358 VN+ + +++ S+++PE+ T + D +C+DL Sbjct: 309 QSQHEVNEDSRSMDQDQTSVSIPENQSTMVTAD----MDNCSDL 348 >gi|150170670 piccolo isoform 2 [Homo sapiens] Length = 4935 Score = 39.3 bits (90), Expect = 0.007 Identities = 50/244 (20%), Positives = 98/244 (40%), Gaps = 22/244 (9%) Query: 162 PYEVLKDSSSQENMVEDCLYETVKEIKEVAAAAHLEKGHSGKAKSTSASKELPGPQTEGK 221 P V +SSSQ+ V + K+ +EV A EK K K T + +++P T + Sbjct: 1136 PMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEA--EKVILEKVKETLSMEKIPPMVTTDQ 1193 Query: 222 AEFAEYASVDRNKKCRQSVNVESILGNSCDPEEEAPPPVPVKLLDENENLQEKEGGEAEE 281 + E + ++++K +E+ P P KL+ E E ++ +E E Sbjct: 1194 KQ--EESKLEKDKASAL--------------QEKKPLPEEKKLIPEEEKIRSEEKKPLLE 1237 Query: 282 SATDTTSETNKRFSSLSYKSREEDPTLTEEEISAMYSSVNKPGQLVNKSGQSLTVPESTY 341 T + + + E+ L + ++ + G++ K+ Q P++ Sbjct: 1238 EKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLE--GRVAPKTVQEGKQPQTKM 1295 Query: 342 TSI-QGDPQRSPSSCNDLYATVKDFEKTPNSTLPPAGRP-SEEPEPDYEAIQTLNREEEK 399 + G PQ P + T+K+ + P + P P E+ E + + T + ++ K Sbjct: 1296 EGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPK 1355 Query: 400 ATLG 403 + G Sbjct: 1356 SPQG 1359 >gi|150378539 piccolo isoform 1 [Homo sapiens] Length = 5142 Score = 39.3 bits (90), Expect = 0.007 Identities = 50/244 (20%), Positives = 98/244 (40%), Gaps = 22/244 (9%) Query: 162 PYEVLKDSSSQENMVEDCLYETVKEIKEVAAAAHLEKGHSGKAKSTSASKELPGPQTEGK 221 P V +SSSQ+ V + K+ +EV A EK K K T + +++P T + Sbjct: 1136 PMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEA--EKVILEKVKETLSMEKIPPMVTTDQ 1193 Query: 222 AEFAEYASVDRNKKCRQSVNVESILGNSCDPEEEAPPPVPVKLLDENENLQEKEGGEAEE 281 + E + ++++K +E+ P P KL+ E E ++ +E E Sbjct: 1194 KQ--EESKLEKDKASAL--------------QEKKPLPEEKKLIPEEEKIRSEEKKPLLE 1237 Query: 282 SATDTTSETNKRFSSLSYKSREEDPTLTEEEISAMYSSVNKPGQLVNKSGQSLTVPESTY 341 T + + + E+ L + ++ + G++ K+ Q P++ Sbjct: 1238 EKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLE--GRVAPKTVQEGKQPQTKM 1295 Query: 342 TSI-QGDPQRSPSSCNDLYATVKDFEKTPNSTLPPAGRP-SEEPEPDYEAIQTLNREEEK 399 + G PQ P + T+K+ + P + P P E+ E + + T + ++ K Sbjct: 1296 EGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPK 1355 Query: 400 ATLG 403 + G Sbjct: 1356 SPQG 1359 >gi|55741677 SET domain containing 1A [Homo sapiens] Length = 1707 Score = 38.5 bits (88), Expect = 0.012 Identities = 36/128 (28%), Positives = 57/128 (44%), Gaps = 13/128 (10%) Query: 267 ENENLQEKEGGEAEESATDTTSETNKRFSSLSYKSREEDPTLTEEEISAMYSSVNKPGQL 326 EN++ + E + S++ ++S ++ SS S +S ED EEE A S + P + Sbjct: 1026 ENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDE--EEEERPAALPSASPPPRE 1083 Query: 327 V---NKSGQSLTVPESTYTS-IQGDPQRSPSSCNDLYATVKDFEKTPNSTL----PPAGR 378 V + + VPE S + P++ S T E P++ L PPAG Sbjct: 1084 VPVPTPAPVEVPVPERVAGSPVTPLPEQEASPARPAGPTE---ESPPSAPLRPPEPPAGP 1140 Query: 379 PSEEPEPD 386 P+ P PD Sbjct: 1141 PAPAPRPD 1148 >gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] Length = 2400 Score = 38.5 bits (88), Expect = 0.012 Identities = 48/225 (21%), Positives = 93/225 (41%), Gaps = 12/225 (5%) Query: 182 ETVKEIKEVAAAAHLEKGHSGKAKSTSASKELPGPQTEGKAEFAEYASVDRNKKCRQSVN 241 E E + V A + ++ S+++ P+ EG+A+ E V+ + V Sbjct: 1843 EAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQ-PESEDVE-TPEAEWEVQ 1900 Query: 242 VESILGNSCDPEEEAPPPVP-VKLLD-ENENLQEKEGGEA---EESATDTTSETNKRFSS 296 ES + + E+EA P V+ L+ E E+ E EG EA EE+A + +T Sbjct: 1901 PESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEV 1960 Query: 297 LSYKSREEDPTLTEEEISAMYSSV---NKPGQLVNKSGQSLTVPESTYTSIQGDPQRSPS 353 + + EE+ E++ A+ V G+ +S + + PE+ + + + P Sbjct: 1961 IESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPES-EDVEAPEAEGEMQEAEEEAQPE 2019 Query: 354 SCNDLYATVKDFEKTPNSTLPPAGRPSEEPEPDYEAIQTLNREEE 398 S + + A K + + + +P+ + ++ EEE Sbjct: 2020 S-DGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEE 2063 Score = 31.2 bits (69), Expect = 1.9 Identities = 55/274 (20%), Positives = 106/274 (38%), Gaps = 26/274 (9%) Query: 90 GDILSEDSTLTCMQHYEEVQTSASDLLDSQDSTGKPKCHQSRELPRIPPESAVDTMLTAR 149 GD+ E+ C + + A + + + S L ++ + + + Sbjct: 1248 GDL--ENQQQCCFPTFLNARACACATNEDEAERDSEEQRASSNLEQLAENTVQEEVQLEE 1305 Query: 150 SVDGDQGLGMEGPYEVLKDSSSQENMVEDCLY-ETVKEIK------EVAAAAHLEK--GH 200 + +G +G G++ L+++ ++E + E+ + E KE + E A +E+ G Sbjct: 1306 TKEGTEGEGLQEEAVQLEETKTEEGLQEEGVQLEETKETEGEGQQEEEAQLEEIEETGGE 1365 Query: 201 SGKAKSTSASKELPGPQTEGKAEFAEYASVDRNKKCRQSVNVESILGNSCDPEEEAPPPV 260 + + + GP+ + E E + SV+ + + EA P Sbjct: 1366 GLQEEGVQLEEVKEGPEGGLQGEALEEGLKEEGLPEEGSVHGQEL--------SEASSP- 1416 Query: 261 PVKLLDENENLQEKEGGEAEESATDTTSETNKRFSSLSYKSREEDPTLTEEEI-SAMYSS 319 K E++ +QE+E G A SA +E + + E DP+ +E + S + Sbjct: 1417 DGKGSQEDDPVQEEEAGRASASAEPCPAEGTEEPTEPPSHLSETDPSASERQSGSQLEPG 1476 Query: 320 VNKPGQLVNKSGQSLTVPESTYTSIQGDPQRSPS 353 + KP GQ T + T QG +RS S Sbjct: 1477 LEKPPG-ATMMGQEHTQAQPT----QGAAERSSS 1505 >gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform 9 [Homo sapiens] Length = 771 Score = 38.1 bits (87), Expect = 0.016 Identities = 57/272 (20%), Positives = 103/272 (37%), Gaps = 38/272 (13%) Query: 167 KDSSSQENMVEDCLYETVKEIKEVAAAAH--LEKGHSGKAKSTSASKELPGPQTE----- 219 ++ +E E+ E +E + +A H + + +S K K++ S+ P P E Sbjct: 178 REQKERERRAEERRKE--REARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELG 235 Query: 220 -GK--------------AEFAEYASVDRNKKCRQSVNVESILGNSCDPEEEAPPPVPVKL 264 G+ ++ + + +R +S + ES G+ + EEE Sbjct: 236 DGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGST 295 Query: 265 LDENENLQEKEGGEAEESATDTTSETNKRFSSLSYKSREEDPTLTEEEISAMYSSVNKPG 324 +E+E +E+E E EE+ +++ + + +S + ED EE + + V Sbjct: 296 SEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSED----EERENENHLLVVPES 351 Query: 325 QLVNKSGQSLTVPESTYTSIQGDPQRSPSSCNDLYATVKDFEKTPNSTLPPAGRPSEEPE 384 + SG+S E +G PQ S + D P P+ + Sbjct: 352 RFDRDSGESEEAEEEVG---EGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQGC 408 Query: 385 PDYEAIQTLNREEEKATLGTNGHHGLVPKEND 416 E Q LNR EE G +G+V + D Sbjct: 409 RSVEEFQCLNRIEE-------GTYGVVYRAKD 433 >gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform 8 [Homo sapiens] Length = 780 Score = 38.1 bits (87), Expect = 0.016 Identities = 57/272 (20%), Positives = 103/272 (37%), Gaps = 38/272 (13%) Query: 167 KDSSSQENMVEDCLYETVKEIKEVAAAAH--LEKGHSGKAKSTSASKELPGPQTE----- 219 ++ +E E+ E +E + +A H + + +S K K++ S+ P P E Sbjct: 187 REQKERERRAEERRKE--REARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELG 244 Query: 220 -GK--------------AEFAEYASVDRNKKCRQSVNVESILGNSCDPEEEAPPPVPVKL 264 G+ ++ + + +R +S + ES G+ + EEE Sbjct: 245 DGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGST 304 Query: 265 LDENENLQEKEGGEAEESATDTTSETNKRFSSLSYKSREEDPTLTEEEISAMYSSVNKPG 324 +E+E +E+E E EE+ +++ + + +S + ED EE + + V Sbjct: 305 SEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSED----EERENENHLLVVPES 360 Query: 325 QLVNKSGQSLTVPESTYTSIQGDPQRSPSSCNDLYATVKDFEKTPNSTLPPAGRPSEEPE 384 + SG+S E +G PQ S + D P P+ + Sbjct: 361 RFDRDSGESEEAEEEVG---EGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQGC 417 Query: 385 PDYEAIQTLNREEEKATLGTNGHHGLVPKEND 416 E Q LNR EE G +G+V + D Sbjct: 418 RSVEEFQCLNRIEE-------GTYGVVYRAKD 442 >gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform 5 [Homo sapiens] Length = 748 Score = 38.1 bits (87), Expect = 0.016 Identities = 57/272 (20%), Positives = 103/272 (37%), Gaps = 38/272 (13%) Query: 167 KDSSSQENMVEDCLYETVKEIKEVAAAAH--LEKGHSGKAKSTSASKELPGPQTE----- 219 ++ +E E+ E +E + +A H + + +S K K++ S+ P P E Sbjct: 155 REQKERERRAEERRKE--REARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELG 212 Query: 220 -GK--------------AEFAEYASVDRNKKCRQSVNVESILGNSCDPEEEAPPPVPVKL 264 G+ ++ + + +R +S + ES G+ + EEE Sbjct: 213 DGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGST 272 Query: 265 LDENENLQEKEGGEAEESATDTTSETNKRFSSLSYKSREEDPTLTEEEISAMYSSVNKPG 324 +E+E +E+E E EE+ +++ + + +S + ED EE + + V Sbjct: 273 SEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSED----EERENENHLLVVPES 328 Query: 325 QLVNKSGQSLTVPESTYTSIQGDPQRSPSSCNDLYATVKDFEKTPNSTLPPAGRPSEEPE 384 + SG+S E +G PQ S + D P P+ + Sbjct: 329 RFDRDSGESEEAEEEVG---EGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQGC 385 Query: 385 PDYEAIQTLNREEEKATLGTNGHHGLVPKEND 416 E Q LNR EE G +G+V + D Sbjct: 386 RSVEEFQCLNRIEE-------GTYGVVYRAKD 410 >gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform 4 [Homo sapiens] Length = 737 Score = 38.1 bits (87), Expect = 0.016 Identities = 57/272 (20%), Positives = 103/272 (37%), Gaps = 38/272 (13%) Query: 167 KDSSSQENMVEDCLYETVKEIKEVAAAAH--LEKGHSGKAKSTSASKELPGPQTE----- 219 ++ +E E+ E +E + +A H + + +S K K++ S+ P P E Sbjct: 144 REQKERERRAEERRKE--REARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELG 201 Query: 220 -GK--------------AEFAEYASVDRNKKCRQSVNVESILGNSCDPEEEAPPPVPVKL 264 G+ ++ + + +R +S + ES G+ + EEE Sbjct: 202 DGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGST 261 Query: 265 LDENENLQEKEGGEAEESATDTTSETNKRFSSLSYKSREEDPTLTEEEISAMYSSVNKPG 324 +E+E +E+E E EE+ +++ + + +S + ED EE + + V Sbjct: 262 SEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSED----EERENENHLLVVPES 317 Query: 325 QLVNKSGQSLTVPESTYTSIQGDPQRSPSSCNDLYATVKDFEKTPNSTLPPAGRPSEEPE 384 + SG+S E +G PQ S + D P P+ + Sbjct: 318 RFDRDSGESEEAEEEVG---EGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQGC 374 Query: 385 PDYEAIQTLNREEEKATLGTNGHHGLVPKEND 416 E Q LNR EE G +G+V + D Sbjct: 375 RSVEEFQCLNRIEE-------GTYGVVYRAKD 399 >gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform 2 [Homo sapiens] Length = 782 Score = 38.1 bits (87), Expect = 0.016 Identities = 57/272 (20%), Positives = 103/272 (37%), Gaps = 38/272 (13%) Query: 167 KDSSSQENMVEDCLYETVKEIKEVAAAAH--LEKGHSGKAKSTSASKELPGPQTE----- 219 ++ +E E+ E +E + +A H + + +S K K++ S+ P P E Sbjct: 189 REQKERERRAEERRKE--REARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELG 246 Query: 220 -GK--------------AEFAEYASVDRNKKCRQSVNVESILGNSCDPEEEAPPPVPVKL 264 G+ ++ + + +R +S + ES G+ + EEE Sbjct: 247 DGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGST 306 Query: 265 LDENENLQEKEGGEAEESATDTTSETNKRFSSLSYKSREEDPTLTEEEISAMYSSVNKPG 324 +E+E +E+E E EE+ +++ + + +S + ED EE + + V Sbjct: 307 SEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSED----EERENENHLLVVPES 362 Query: 325 QLVNKSGQSLTVPESTYTSIQGDPQRSPSSCNDLYATVKDFEKTPNSTLPPAGRPSEEPE 384 + SG+S E +G PQ S + D P P+ + Sbjct: 363 RFDRDSGESEEAEEEVG---EGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQGC 419 Query: 385 PDYEAIQTLNREEEKATLGTNGHHGLVPKEND 416 E Q LNR EE G +G+V + D Sbjct: 420 RSVEEFQCLNRIEE-------GTYGVVYRAKD 444 >gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] Length = 770 Score = 37.4 bits (85), Expect = 0.027 Identities = 60/279 (21%), Positives = 107/279 (38%), Gaps = 52/279 (18%) Query: 167 KDSSSQENMVEDCLYETVKEIKEVAAAAH--LEKGHSGKAKSTSASKELPGPQTE----- 219 ++ +E E+ E +E + +A H + + +S K K++ S+ P P E Sbjct: 177 REQKERERRAEERRKE--REARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELG 234 Query: 220 -GK--------------AEFAEYASVDRNKKCRQSVNVESILGNSCDPEEEAPPPVPVKL 264 G+ ++ + + +R +S + ES G+ + EEE Sbjct: 235 DGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGST 294 Query: 265 LDENENLQEKEGGEAEESATDTTSETNKRFSSLSYKSREEDPTLTEEEISAMYSSVNKPG 324 +E+E +E+E E EE+ +++ + + +S + ED EE + + V Sbjct: 295 SEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSED----EERENENHLLVVPES 350 Query: 325 QLVNKSGQSLTVPESTYTSIQGDPQRSPSSCNDLYATVKDFEKTPNSTLP-------PAG 377 + SG+S E +G PQ S T D+ + LP P Sbjct: 351 RFDRDSGESEEAEEEVG---EGTPQSSA-------LTEGDYVPDSPALLPIELKQELPKY 400 Query: 378 RPSEEPEPDYEAIQTLNREEEKATLGTNGHHGLVPKEND 416 P+ + E Q LNR EE G +G+V + D Sbjct: 401 LPALQGCRSVEEFQCLNRIEE-------GTYGVVYRAKD 432 >gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] Length = 780 Score = 37.4 bits (85), Expect = 0.027 Identities = 60/279 (21%), Positives = 107/279 (38%), Gaps = 52/279 (18%) Query: 167 KDSSSQENMVEDCLYETVKEIKEVAAAAH--LEKGHSGKAKSTSASKELPGPQTE----- 219 ++ +E E+ E +E + +A H + + +S K K++ S+ P P E Sbjct: 187 REQKERERRAEERRKE--REARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELG 244 Query: 220 -GK--------------AEFAEYASVDRNKKCRQSVNVESILGNSCDPEEEAPPPVPVKL 264 G+ ++ + + +R +S + ES G+ + EEE Sbjct: 245 DGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGST 304 Query: 265 LDENENLQEKEGGEAEESATDTTSETNKRFSSLSYKSREEDPTLTEEEISAMYSSVNKPG 324 +E+E +E+E E EE+ +++ + + +S + ED EE + + V Sbjct: 305 SEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSED----EERENENHLLVVPES 360 Query: 325 QLVNKSGQSLTVPESTYTSIQGDPQRSPSSCNDLYATVKDFEKTPNSTLP-------PAG 377 + SG+S E +G PQ S T D+ + LP P Sbjct: 361 RFDRDSGESEEAEEEVG---EGTPQSSA-------LTEGDYVPDSPALLPIELKQELPKY 410 Query: 378 RPSEEPEPDYEAIQTLNREEEKATLGTNGHHGLVPKEND 416 P+ + E Q LNR EE G +G+V + D Sbjct: 411 LPALQGCRSVEEFQCLNRIEE-------GTYGVVYRAKD 442 >gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] Length = 2454 Score = 37.4 bits (85), Expect = 0.027 Identities = 77/379 (20%), Positives = 135/379 (35%), Gaps = 53/379 (13%) Query: 37 CSSCDREKKPRQHSGDHENLMNVPSDKEMFSRSVTSLATDAPASSEQN-------GALTN 89 C+S D+ K R + NL + + KE+ S S +S DA SSE N + Sbjct: 1084 CNSSDKRLK-RIELRERRNLSSKRNTKEIQSGSSSS---DAEESSEDNKKKKQRTSSKKK 1139 Query: 90 GDILSEDS-----TLTCMQHYEEVQTSASDLLDS-QDSTGKPKCHQSRELPRIPPESAVD 143 I+ E T T + + +S+SD+ D Q+S G+ + + P + + Sbjct: 1140 AVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKP-VTENLVLS 1198 Query: 144 TMLTARSVDGDQGLGMEGPYEVLKDSSSQE---NMVEDCLYETVK-EIKEVAAAAHLEKG 199 + GD+ L P V D + + + L E +K + + ++ Sbjct: 1199 SHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEP 1258 Query: 200 HSGKAKSTSASKELPGPQTEGKAEFAEYASVDRNKKCRQSVNVESILGNSCDPEEEAPPP 259 GK ++ ++E PG +++ + VN ES D EE P Sbjct: 1259 EEGKKRTGKQNEENPG-----------------DEEAKNQVNSES----DSDSEESKKPR 1297 Query: 260 VPVKLLDENENLQEKEGGEAEESATDTTSETNKRFSSLSYKSREEDPTLTEEEISAMYSS 319 +LL + + E GE +++ E R ED E +S S Sbjct: 1298 YRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSE 1357 Query: 320 VNKPGQLVNKSGQSLTVPESTYTSIQGDPQRSPSSCNDLYATVKDFEKTPNSTLPPAGRP 379 + +S + + E+ + Q +R +K E + + + Sbjct: 1358 SEDEQRPRTRSAKKAELEENQRSYKQKKKRR----------RIKVQEDSSSENKSNSEEE 1407 Query: 380 SEEPEPDYEAIQTLNREEE 398 EE E + E + EEE Sbjct: 1408 EEEKEEEEEEEEEEEEEEE 1426 >gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] Length = 2492 Score = 37.4 bits (85), Expect = 0.027 Identities = 77/379 (20%), Positives = 135/379 (35%), Gaps = 53/379 (13%) Query: 37 CSSCDREKKPRQHSGDHENLMNVPSDKEMFSRSVTSLATDAPASSEQN-------GALTN 89 C+S D+ K R + NL + + KE+ S S +S DA SSE N + Sbjct: 1122 CNSSDKRLK-RIELRERRNLSSKRNTKEIQSGSSSS---DAEESSEDNKKKKQRTSSKKK 1177 Query: 90 GDILSEDS-----TLTCMQHYEEVQTSASDLLDS-QDSTGKPKCHQSRELPRIPPESAVD 143 I+ E T T + + +S+SD+ D Q+S G+ + + P + + Sbjct: 1178 AVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKP-VTENLVLS 1236 Query: 144 TMLTARSVDGDQGLGMEGPYEVLKDSSSQE---NMVEDCLYETVK-EIKEVAAAAHLEKG 199 + GD+ L P V D + + + L E +K + + ++ Sbjct: 1237 SHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEP 1296 Query: 200 HSGKAKSTSASKELPGPQTEGKAEFAEYASVDRNKKCRQSVNVESILGNSCDPEEEAPPP 259 GK ++ ++E PG +++ + VN ES D EE P Sbjct: 1297 EEGKKRTGKQNEENPG-----------------DEEAKNQVNSES----DSDSEESKKPR 1335 Query: 260 VPVKLLDENENLQEKEGGEAEESATDTTSETNKRFSSLSYKSREEDPTLTEEEISAMYSS 319 +LL + + E GE +++ E R ED E +S S Sbjct: 1336 YRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSE 1395 Query: 320 VNKPGQLVNKSGQSLTVPESTYTSIQGDPQRSPSSCNDLYATVKDFEKTPNSTLPPAGRP 379 + +S + + E+ + Q +R +K E + + + Sbjct: 1396 SEDEQRPRTRSAKKAELEENQRSYKQKKKRR----------RIKVQEDSSSENKSNSEEE 1445 Query: 380 SEEPEPDYEAIQTLNREEE 398 EE E + E + EEE Sbjct: 1446 EEEKEEEEEEEEEEEEEEE 1464 >gi|38372901 Sp1 transcription factor isoform a [Homo sapiens] Length = 785 Score = 37.0 bits (84), Expect = 0.035 Identities = 36/156 (23%), Positives = 63/156 (40%), Gaps = 21/156 (13%) Query: 33 LIFLCSSCDREKKPRQHSGDHENLMNVPSDKEMFSRS------------VTSLATDAPAS 80 L L ++C R + P ++S + + E+ + ++S + P S Sbjct: 61 LALLAATCSRIESPNENSNNSQGPSQSGGTGELDLTATQLSQGANGWQIISSSSGATPTS 120 Query: 81 SEQNGALTNGDILSEDSTLTCMQHYEEVQTSASDLLDSQDSTGKPKCHQSRELPRIPPES 140 EQ+G+ TNG SE S + + V +A +L + Q TG LP + P Sbjct: 121 KEQSGSSTNGSNGSESSKNRTVSGGQYVVAAAPNLQNQQVLTG---------LPGVMPNI 171 Query: 141 AVDTMLTARSVDGDQGLGMEGPYEVLKDSSSQENMV 176 + ++VDG Q +V +D S Q ++ Sbjct: 172 QYQVIPQFQTVDGQQLQFAATGAQVQQDGSGQIQII 207 >gi|218751903 Sp1 transcription factor isoform b [Homo sapiens] Length = 778 Score = 37.0 bits (84), Expect = 0.035 Identities = 36/156 (23%), Positives = 63/156 (40%), Gaps = 21/156 (13%) Query: 33 LIFLCSSCDREKKPRQHSGDHENLMNVPSDKEMFSRS------------VTSLATDAPAS 80 L L ++C R + P ++S + + E+ + ++S + P S Sbjct: 54 LALLAATCSRIESPNENSNNSQGPSQSGGTGELDLTATQLSQGANGWQIISSSSGATPTS 113 Query: 81 SEQNGALTNGDILSEDSTLTCMQHYEEVQTSASDLLDSQDSTGKPKCHQSRELPRIPPES 140 EQ+G+ TNG SE S + + V +A +L + Q TG LP + P Sbjct: 114 KEQSGSSTNGSNGSESSKNRTVSGGQYVVAAAPNLQNQQVLTG---------LPGVMPNI 164 Query: 141 AVDTMLTARSVDGDQGLGMEGPYEVLKDSSSQENMV 176 + ++VDG Q +V +D S Q ++ Sbjct: 165 QYQVIPQFQTVDGQQLQFAATGAQVQQDGSGQIQII 200 >gi|4505129 mutated in colorectal cancers isoform 2 [Homo sapiens] Length = 829 Score = 37.0 bits (84), Expect = 0.035 Identities = 27/100 (27%), Positives = 50/100 (50%), Gaps = 9/100 (9%) Query: 264 LLDENENLQEKEGGEAEESATDTTS---ETNKRFSSLSYKSREEDPTLTE--EEISAMYS 318 L+ E+E++QE+ EE T+ S E NK+ L + E+ +E E+S Sbjct: 63 LMREHEDVQERTTLRYEERITELHSVIAELNKKIDRLQGTTIREEDEYSELRSELSQSQH 122 Query: 319 SVNKPGQLVNKSGQSLTVPESTYTSIQGDPQRSPSSCNDL 358 VN+ + +++ S+++PE+ T + D +C+DL Sbjct: 123 EVNEDSRSMDQDQTSVSIPENQSTMVTAD----MDNCSDL 158 >gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] Length = 1301 Score = 36.6 bits (83), Expect = 0.045 Identities = 57/381 (14%), Positives = 134/381 (35%), Gaps = 7/381 (1%) Query: 38 SSCDREKKPRQHSGDHENLMNVPSDKEMFSRSVTSLATDAPASSEQNGALTNGDILSEDS 97 SS + +S D+ N + + + S +S ++D+ SS+ + + + D S DS Sbjct: 917 SSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDS 976 Query: 98 TLTCMQHYEEVQTSASDLLDSQDSTGKPKCHQSRELPRIPPESAVDTMLTARSVDGDQGL 157 + + + +SD DS DS+ S + ++ D+ ++ S + Sbjct: 977 SDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD--SSDSSNSSDSSNSSDSSNSSDSS 1034 Query: 158 GMEGPYEVLKDSSSQENMVEDCLYETVKEIKEVAAAAHLEKGHSGKAKSTSASKELPGPQ 217 + S S ++ ++ ++ + S + +S S + Sbjct: 1035 DSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSS 1094 Query: 218 TEGKAEFAEYASVDRNKKCRQSVNVESILGNSCDPEEEAPPPVPVKLLDENENLQEKEGG 277 + + +S + + S +S D + + D +++ + + Sbjct: 1095 DSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSS 1154 Query: 278 EAEESATDTTSETNKRFSSLSYKSREEDPTLTEEEISAMYSSVNKPGQLVNKSGQSLTVP 337 ++ +S+ + S + S S S D + + + + SS + + S S Sbjct: 1155 DSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1214 Query: 338 ESTYTSIQGDPQRSPSSCNDLYATVKDFEKTPNSTLPPAGRPSEEPEPDYEAIQTLNREE 397 +S+ +S D S S D + +S+ S + ++ N E Sbjct: 1215 DSSDSSDSSDSSDSSDSNES-----SDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDES 1269 Query: 398 EKATLGTNGHHGLVPKENDYE 418 + + NG++ ++D E Sbjct: 1270 DSQSKSGNGNNNGSDSDSDSE 1290 Score = 32.7 bits (73), Expect = 0.66 Identities = 55/313 (17%), Positives = 117/313 (37%), Gaps = 22/313 (7%) Query: 50 SGDHENLMNVPSDKEMFSRSVTSLATDAPASSEQNGALTNGDILSEDSTLTCMQHYEEVQ 109 S D + + S + + S +S ++D+ SSE + + + D S DS+ + + + Sbjct: 668 SSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSD 727 Query: 110 TSASDLLDSQDSTGKPKCHQSRELPRIPPES-AVDTMLTARSVDGDQGLGMEGPYEVLKD 168 +S S DS DS+ S + S + D+ ++ S D D Sbjct: 728 SSNSS--DSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDS----------SD 775 Query: 169 SSSQENMVEDCLYETVKEIKEVAAAAHLEKGHSGKAKSTSASKELPGPQTEGKAEFAEYA 228 SS N + + + + ++ + +S + +S S + + + ++ Sbjct: 776 SSDSSNSSDSNDSSNSSDSSDSSNSS--DSSNSSDSSDSSDSSDSDSSNSSDSSNSSD-- 831 Query: 229 SVDRNKKCRQSVNVESILGNSCDPEEEAPPPVPVKLLDENENLQEKEGGEAEES-----A 283 S D + S + +S G+ D + D +++ + ++ +S + Sbjct: 832 SSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNS 891 Query: 284 TDTTSETNKRFSSLSYKSREEDPTLTEEEISAMYSSVNKPGQLVNKSGQSLTVPESTYTS 343 +D++ +N S S S D + + + SS + + S S +S+ +S Sbjct: 892 SDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSS 951 Query: 344 IQGDPQRSPSSCN 356 D S S N Sbjct: 952 NSSDSSNSSDSSN 964 Score = 32.7 bits (73), Expect = 0.66 Identities = 52/317 (16%), Positives = 110/317 (34%), Gaps = 11/317 (3%) Query: 38 SSCDREKKPRQHSGDHENLMNVPSDKEMFSRSVTSLATDAPASSEQNGALTNGDILSEDS 97 SS + S D N + S +S ++D+ SS+ + + + D S +S Sbjct: 764 SSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNS 823 Query: 98 TLTCMQHYEEVQTSASDLLDSQDSTGKPKCHQSRELPRIPPESAVDTMLTARSVDGDQGL 157 + + +++SD DS DS+ S + D+ ++ S D Sbjct: 824 SDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDS- 882 Query: 158 GMEGPYEVLKDSSSQENMVEDCLYETVKEIKEVAAAAHLEKGHSGKAKSTSASKELPGPQ 217 DSS N + ++ ++ + S + S S + Sbjct: 883 SDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSS 942 Query: 218 TEGKAEFAEYASVDRNKKCRQSVNVESILGNSCDPEEEAPPPVPVKLLDENENLQEKEGG 277 + + +S D + S + +S NS D + + + +++ + Sbjct: 943 DSSDSSDSSNSS-DSSNSSDSSNSSDSSDSNSSDSSDSS---------NSSDSSDSSDSS 992 Query: 278 EAEESATDTTSETNKRFSSLSYKSREEDPTLTEEEISAMYSSVNKPGQLVNKSGQSLTVP 337 ++ +S+ + S + S S S D + + + ++ SS + + S S Sbjct: 993 DSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1052 Query: 338 ESTYTSIQGDPQRSPSS 354 +S+ +S D S S Sbjct: 1053 DSSNSSDSSDSSDSSDS 1069 >gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sapiens] Length = 699 Score = 36.6 bits (83), Expect = 0.045 Identities = 43/225 (19%), Positives = 84/225 (37%), Gaps = 7/225 (3%) Query: 190 VAAAAHLEKGHSGKAKSTSASKELPGPQTEGKAEFAEYASVDRNKKCRQSVNVESILGNS 249 VA A + S S+ +E+ GP + A A+ + K ++ S +S Sbjct: 74 VAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASESSSSEESS 133 Query: 250 CDPEEEAPPPVPVKLLDENENLQEKEGGEAEESATDTTSETNKRFSSLSYKSREEDPTLT 309 D +EE PV+ + Q K + A + S+++ SS + + P +T Sbjct: 134 DDDDEEDQKKQPVQ---KGVKPQAKAAKAPPKKAKSSDSDSDS--SSEDEPPKNQKPKIT 188 Query: 310 EEEISAMYSSVNKPGQLVNK--SGQSLTVPESTYTSIQGDPQRSPSSCNDLYATVKDFEK 367 + A + KP + K +G++ + S+ +S D + TV + Sbjct: 189 PVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQV 248 Query: 368 TPNSTLPPAGRPSEEPEPDYEAIQTLNREEEKATLGTNGHHGLVP 412 + + A P+ + ++ E++K G + VP Sbjct: 249 VAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVP 293 Score = 35.0 bits (79), Expect = 0.13 Identities = 76/374 (20%), Positives = 136/374 (36%), Gaps = 46/374 (12%) Query: 59 VPSDKEMFSRSVTSLATDAPASSEQNGALT------NGDILSEDSTLTCMQHYEEVQTSA 112 + + K S S +S ++ + S E+ A T ++++ + +S Sbjct: 209 IANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSE 268 Query: 113 SDLLDSQDSTGKPKCHQSRELPRIPPESAVDTMLTARSVDGDQGLGMEGPYEVLKDSSSQ 172 D ++ KP ++ +PP SA + + + + + P E +DSS + Sbjct: 269 DSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDE 328 Query: 173 ENMVEDCLYETVKEIKEVAAAAHLEKGHSGKAKSTSASKELPGPQTEGKAEFAEYASVDR 232 + + E K + + K K + S+S +E ++ A + Sbjct: 329 SDSSSE---EEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTK 385 Query: 233 NKKCRQSVNVESILGNSCDPEEEAPPPVPV----KLL----DENENLQEKEGGEAEES-- 282 N S N ++ S + A P PV KLL D + + +E E E++ Sbjct: 386 N-----SSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKK 440 Query: 283 --ATDTTSETNKRFSSLSYK----------SREEDPTLTEEEISAMYSSVNKPGQLVNKS 330 AT T K SL K S + + EEE S+V K Q V Sbjct: 441 MVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGG 500 Query: 331 GQSLTVPESTYTSIQGDPQRSPSSCNDLYATVKDFEK-----TPNSTLPPAGRPSEEPEP 385 P ++ +G + S SS +D ++ ++ EK +P P A S Sbjct: 501 ----AAPSKPASAKKGKAESSNSSSSD-DSSEEEEEKLKGKGSPRPQAPKANGTSALTAQ 555 Query: 386 DYEAIQTLNREEEK 399 + +A + EEE+ Sbjct: 556 NGKAAKNSEEEEEE 569 >gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isoform 3 [Homo sapiens] Length = 526 Score = 36.6 bits (83), Expect = 0.045 Identities = 43/195 (22%), Positives = 75/195 (38%), Gaps = 14/195 (7%) Query: 222 AEFAEYASVDRNKKCRQSVNVESILGNSCDPEEEAPPPVPVKLLDENENLQEKEGGEAEE 281 ++ + + +R +S + ES G+ + EEE +E+E +E+E E EE Sbjct: 8 SDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEE 67 Query: 282 SATDTTSETNKRFSSLSYKSREEDPTLTEEEISAMYSSVNKPGQLVNKSGQSLTVPESTY 341 + +++ + + +S + ED EE + + V + SG+S E Sbjct: 68 TGSNSEEASEQSAEEVSEEEMSED----EERENENHLLVVPESRFDRDSGESEEAEEEVG 123 Query: 342 TSIQGDPQRSPSSCNDLYATVKDFEKTPNSTLPPAGRPSEEPEPDYEAIQTLNREEEKAT 401 +G PQ S + D P P+ + E Q LNR EE Sbjct: 124 ---EGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQGCRSVEEFQCLNRIEE--- 177 Query: 402 LGTNGHHGLVPKEND 416 G +G+V + D Sbjct: 178 ----GTYGVVYRAKD 188 >gi|23111062 splicing factor, arginine/serine-rich 8 [Homo sapiens] Length = 951 Score = 36.2 bits (82), Expect = 0.059 Identities = 60/238 (25%), Positives = 96/238 (40%), Gaps = 46/238 (19%) Query: 153 GDQGLGMEGPYEVLKDSSSQE--NMVEDCLYETVKEIKEVAAAAHLEKGHSGKAKSTSAS 210 GD + P E DS+ ++ + ED E E+ A SG K S+S Sbjct: 512 GDSMQAVSAPEEAPTDSAPEKPSDAGEDGAPEDAAEVGARAG--------SGGKKEASSS 563 Query: 211 KELPGPQTEGKAEFAEYASVDRNKKCRQSVNVESILGNSCDPEEEAPPPVPVKLLDENEN 270 K +P +GK A +A + K ++ N P E+ VKL D++++ Sbjct: 564 KTVP----DGKLVKASFAPISFAIKAKE---------NDLLPLEKNR----VKLDDDSDD 606 Query: 271 LQE-KEGGEAEESATDTTSETNKRFSSLSYKSREEDPTLTEEEISAMYSSVNKPGQLVNK 329 +E KEG E+ SA +T N + E+ P LT+EE+ A + +L Sbjct: 607 DEESKEGQESSSSAANT----NPAVAPPCVVVEEKKPQLTQEELEAKQAKQKLEDRLAAA 662 Query: 330 SGQSL--TVPESTYTSIQGDPQRSPSSCNDLYATVKDFEKTPNSTLP--PAGRPSEEP 383 + + L ES +Q + +R + F +T + LP AG+ E P Sbjct: 663 AREKLAQASKESKEKQLQAERKRKAAL----------FLQTLKNPLPEAEAGKIEESP 710 >gi|113415504 PREDICTED: similar to ribonucleic acid binding protein S1 [Homo sapiens] Length = 305 Score = 35.8 bits (81), Expect = 0.078 Identities = 48/171 (28%), Positives = 67/171 (39%), Gaps = 13/171 (7%) Query: 240 VNVESILG---NSCDPEEEAPPPVPVK-LLDENENLQEKEGGEAEESATDTTS--ETNKR 293 V +S+LG N+ AP P K DE + K+ G +ES+ +T KR Sbjct: 6 VKKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKR 65 Query: 294 FS----SLSYKSREEDPTLTEEEISAMYSSVNKPGQLVNKSGQSLTVPESTYTSIQGDPQ 349 S S S +SR + + S SS + ++SG S T S+ +S G P Sbjct: 66 HSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSP- 124 Query: 350 RSPS-SCNDLYATVKDFEKTPNSTLPPAGRPSEEPEPDYEAIQTLNREEEK 399 SPS +D + K P R S P+P I L R K Sbjct: 125 -SPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRNVTK 174 >gi|169166499 PREDICTED: similar to ribonucleic acid binding protein S1 [Homo sapiens] Length = 305 Score = 35.8 bits (81), Expect = 0.078 Identities = 48/171 (28%), Positives = 67/171 (39%), Gaps = 13/171 (7%) Query: 240 VNVESILG---NSCDPEEEAPPPVPVK-LLDENENLQEKEGGEAEESATDTTS--ETNKR 293 V +S+LG N+ AP P K DE + K+ G +ES+ +T KR Sbjct: 6 VKKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKR 65 Query: 294 FS----SLSYKSREEDPTLTEEEISAMYSSVNKPGQLVNKSGQSLTVPESTYTSIQGDPQ 349 S S S +SR + + S SS + ++SG S T S+ +S G P Sbjct: 66 HSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSP- 124 Query: 350 RSPS-SCNDLYATVKDFEKTPNSTLPPAGRPSEEPEPDYEAIQTLNREEEK 399 SPS +D + K P R S P+P I L R K Sbjct: 125 -SPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRNVTK 174 >gi|113415498 PREDICTED: similar to ribonucleic acid binding protein S1 [Homo sapiens] Length = 305 Score = 35.8 bits (81), Expect = 0.078 Identities = 48/171 (28%), Positives = 67/171 (39%), Gaps = 13/171 (7%) Query: 240 VNVESILG---NSCDPEEEAPPPVPVK-LLDENENLQEKEGGEAEESATDTTS--ETNKR 293 V +S+LG N+ AP P K DE + K+ G +ES+ +T KR Sbjct: 6 VKKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKR 65 Query: 294 FS----SLSYKSREEDPTLTEEEISAMYSSVNKPGQLVNKSGQSLTVPESTYTSIQGDPQ 349 S S S +SR + + S SS + ++SG S T S+ +S G P Sbjct: 66 HSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSP- 124 Query: 350 RSPS-SCNDLYATVKDFEKTPNSTLPPAGRPSEEPEPDYEAIQTLNREEEK 399 SPS +D + K P R S P+P I L R K Sbjct: 125 -SPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRNVTK 174 >gi|88973230 PREDICTED: similar to ribonucleic acid binding protein S1 isoform 3 [Homo sapiens] Length = 305 Score = 35.8 bits (81), Expect = 0.078 Identities = 48/171 (28%), Positives = 67/171 (39%), Gaps = 13/171 (7%) Query: 240 VNVESILG---NSCDPEEEAPPPVPVK-LLDENENLQEKEGGEAEESATDTTS--ETNKR 293 V +S+LG N+ AP P K DE + K+ G +ES+ +T KR Sbjct: 6 VKKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKR 65 Query: 294 FS----SLSYKSREEDPTLTEEEISAMYSSVNKPGQLVNKSGQSLTVPESTYTSIQGDPQ 349 S S S +SR + + S SS + ++SG S T S+ +S G P Sbjct: 66 HSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSP- 124 Query: 350 RSPS-SCNDLYATVKDFEKTPNSTLPPAGRPSEEPEPDYEAIQTLNREEEK 399 SPS +D + K P R S P+P I L R K Sbjct: 125 -SPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRNVTK 174 >gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] Length = 1020 Score = 35.8 bits (81), Expect = 0.078 Identities = 32/148 (21%), Positives = 59/148 (39%), Gaps = 16/148 (10%) Query: 164 EVLKDSSSQENMVEDCLYETVKEIKEVAAAAHLEKGHSGKAKSTSASKELPGPQTEGKAE 223 E KDS +E ++ V+E KE A E K + K++P P+ E A+ Sbjct: 854 EEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAK 913 Query: 224 FAEYASVDRNKKCRQSVNVESILGNSCDPEEEAPPPVPVKLLDENENLQEKEGGEAEESA 283 V + K ++ V + +E + P + E ++ +E++ + EE Sbjct: 914 ----VEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKP 969 Query: 284 TDTTSETNKRFSSLSYKSREEDPTLTEE 311 K++E+D TL++E Sbjct: 970 KTEA------------KAKEDDKTLSKE 985 >gi|23111036 sorting nexin 1 isoform c [Homo sapiens] Length = 474 Score = 35.4 bits (80), Expect = 0.10 Identities = 34/152 (22%), Positives = 56/152 (36%), Gaps = 14/152 (9%) Query: 247 GNSCDPEEEAPPPVPVKLLDENENLQEKEGGEAEESATDTTSETNKRFSSLSYKSREEDP 306 G C E PPP P E E G +E A D+ +E F+ + S+ + P Sbjct: 5 GGGCSASERLPPPFPGL-----EPESEGAAGGSEPEAGDSDTEGEDIFTGAAVVSKHQSP 59 Query: 307 TLTEEEISAMYSSVNKPGQLVNKSGQSLTVPESTYTSIQGDPQRSPSSCNDLYATVKDFE 366 +T + S K + + Q P+ + + + N K Sbjct: 60 KITTSLLPINNGS--KENGIHEEQDQE---PQDLFADATVELSLDSTQNNQK----KVLA 110 Query: 367 KTPNSTLPPAGRPSEEPEPDYEAIQTLNREEE 398 KT S P S +P+P YE ++ +E++ Sbjct: 111 KTLISLPPQEATNSSKPQPTYEELEEEEQEDQ 142 >gi|23111034 sorting nexin 1 isoform a [Homo sapiens] Length = 522 Score = 35.4 bits (80), Expect = 0.10 Identities = 34/152 (22%), Positives = 56/152 (36%), Gaps = 14/152 (9%) Query: 247 GNSCDPEEEAPPPVPVKLLDENENLQEKEGGEAEESATDTTSETNKRFSSLSYKSREEDP 306 G C E PPP P E E G +E A D+ +E F+ + S+ + P Sbjct: 5 GGGCSASERLPPPFPGL-----EPESEGAAGGSEPEAGDSDTEGEDIFTGAAVVSKHQSP 59 Query: 307 TLTEEEISAMYSSVNKPGQLVNKSGQSLTVPESTYTSIQGDPQRSPSSCNDLYATVKDFE 366 +T + S K + + Q P+ + + + N K Sbjct: 60 KITTSLLPINNGS--KENGIHEEQDQE---PQDLFADATVELSLDSTQNNQK----KVLA 110 Query: 367 KTPNSTLPPAGRPSEEPEPDYEAIQTLNREEE 398 KT S P S +P+P YE ++ +E++ Sbjct: 111 KTLISLPPQEATNSSKPQPTYEELEEEEQEDQ 142 >gi|42518068 trans-golgi network protein 2 [Homo sapiens] Length = 437 Score = 35.4 bits (80), Expect = 0.10 Identities = 38/192 (19%), Positives = 68/192 (35%), Gaps = 12/192 (6%) Query: 245 ILGNSCDPEEEAPPPVPVKLLDENENLQEKEGGEAEESATDTTSETNKRFSSLSYKSREE 304 +L +EEA + + +L ++ GG + T + + SS ++ E+ Sbjct: 20 LLATESVKQEEAGVRPSAGNVSTHPSLSQRPGGSTKSHPEPQTPKDSPSKSSAEAQTPED 79 Query: 305 DPTLTEEEISAMYSSVNKPGQ-------LVNKSGQSLTVPESTYTSIQGDPQRSPSSCND 357 P + E S NK G +KSG + + + + Q S Sbjct: 80 TPNKSGAEAKTQKDSSNKSGAEAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDSTGK 139 Query: 358 LYATVKDFEKTPNSTLPPAGRPSEEPEPDYEAIQTLNREEEKATLGTNGHHGLVPKENDY 417 A + E +PN + A + P QT K +G G PK+ Sbjct: 140 SGAEAQTPEDSPNRSGAEAKTQKDSPSKSGSEAQTTKDVPNK-----SGADGQTPKDGSS 194 Query: 418 ESISDLQQGRDI 429 +S ++ Q +D+ Sbjct: 195 KSGAEDQTPKDV 206 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.305 0.124 0.345 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 18,697,607 Number of Sequences: 37866 Number of extensions: 929902 Number of successful extensions: 3243 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 30 Number of HSP's successfully gapped in prelim test: 180 Number of HSP's that attempted gapping in prelim test: 3020 Number of HSP's gapped (non-prelim): 329 length of query: 432 length of database: 18,247,518 effective HSP length: 105 effective length of query: 327 effective length of database: 14,271,588 effective search space: 4666809276 effective search space used: 4666809276 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 43 (22.0 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.