Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 63054864

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|63054864 phosphoprotein associated with glycosphingolipid
microdomains 1 [Homo sapiens]
         (432 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|63054864 phosphoprotein associated with glycosphingolipid mic...   863   0.0  
gi|146229340 mutated in colorectal cancers isoform 1 [Homo sapiens]    40   0.004
gi|150170670 piccolo isoform 2 [Homo sapiens]                          39   0.007
gi|150378539 piccolo isoform 1 [Homo sapiens]                          39   0.007
gi|55741677 SET domain containing 1A [Homo sapiens]                    39   0.012
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]              39   0.012
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof...    38   0.016
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof...    38   0.016
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof...    38   0.016
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof...    38   0.016
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof...    38   0.016
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]     37   0.027
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]     37   0.027
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]    37   0.027
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]    37   0.027
gi|38372901 Sp1 transcription factor isoform a [Homo sapiens]          37   0.035
gi|218751903 Sp1 transcription factor isoform b [Homo sapiens]         37   0.035
gi|4505129 mutated in colorectal cancers isoform 2 [Homo sapiens]      37   0.035
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    37   0.045
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa...    37   0.045
gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isof...    37   0.045
gi|23111062 splicing factor, arginine/serine-rich 8 [Homo sapiens]     36   0.059
gi|113415504 PREDICTED: similar to ribonucleic acid binding prot...    36   0.078
gi|169166499 PREDICTED: similar to ribonucleic acid binding prot...    36   0.078
gi|113415498 PREDICTED: similar to ribonucleic acid binding prot...    36   0.078
gi|88973230 PREDICTED: similar to ribonucleic acid binding prote...    36   0.078
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     36   0.078
gi|23111036 sorting nexin 1 isoform c [Homo sapiens]                   35   0.10 
gi|23111034 sorting nexin 1 isoform a [Homo sapiens]                   35   0.10 
gi|42518068 trans-golgi network protein 2 [Homo sapiens]               35   0.10 

>gi|63054864 phosphoprotein associated with glycosphingolipid
           microdomains 1 [Homo sapiens]
          Length = 432

 Score =  863 bits (2229), Expect = 0.0
 Identities = 432/432 (100%), Positives = 432/432 (100%)

Query: 1   MGPAGSLLGSGQMQITLWGSLAAVAIFFVITFLIFLCSSCDREKKPRQHSGDHENLMNVP 60
           MGPAGSLLGSGQMQITLWGSLAAVAIFFVITFLIFLCSSCDREKKPRQHSGDHENLMNVP
Sbjct: 1   MGPAGSLLGSGQMQITLWGSLAAVAIFFVITFLIFLCSSCDREKKPRQHSGDHENLMNVP 60

Query: 61  SDKEMFSRSVTSLATDAPASSEQNGALTNGDILSEDSTLTCMQHYEEVQTSASDLLDSQD 120
           SDKEMFSRSVTSLATDAPASSEQNGALTNGDILSEDSTLTCMQHYEEVQTSASDLLDSQD
Sbjct: 61  SDKEMFSRSVTSLATDAPASSEQNGALTNGDILSEDSTLTCMQHYEEVQTSASDLLDSQD 120

Query: 121 STGKPKCHQSRELPRIPPESAVDTMLTARSVDGDQGLGMEGPYEVLKDSSSQENMVEDCL 180
           STGKPKCHQSRELPRIPPESAVDTMLTARSVDGDQGLGMEGPYEVLKDSSSQENMVEDCL
Sbjct: 121 STGKPKCHQSRELPRIPPESAVDTMLTARSVDGDQGLGMEGPYEVLKDSSSQENMVEDCL 180

Query: 181 YETVKEIKEVAAAAHLEKGHSGKAKSTSASKELPGPQTEGKAEFAEYASVDRNKKCRQSV 240
           YETVKEIKEVAAAAHLEKGHSGKAKSTSASKELPGPQTEGKAEFAEYASVDRNKKCRQSV
Sbjct: 181 YETVKEIKEVAAAAHLEKGHSGKAKSTSASKELPGPQTEGKAEFAEYASVDRNKKCRQSV 240

Query: 241 NVESILGNSCDPEEEAPPPVPVKLLDENENLQEKEGGEAEESATDTTSETNKRFSSLSYK 300
           NVESILGNSCDPEEEAPPPVPVKLLDENENLQEKEGGEAEESATDTTSETNKRFSSLSYK
Sbjct: 241 NVESILGNSCDPEEEAPPPVPVKLLDENENLQEKEGGEAEESATDTTSETNKRFSSLSYK 300

Query: 301 SREEDPTLTEEEISAMYSSVNKPGQLVNKSGQSLTVPESTYTSIQGDPQRSPSSCNDLYA 360
           SREEDPTLTEEEISAMYSSVNKPGQLVNKSGQSLTVPESTYTSIQGDPQRSPSSCNDLYA
Sbjct: 301 SREEDPTLTEEEISAMYSSVNKPGQLVNKSGQSLTVPESTYTSIQGDPQRSPSSCNDLYA 360

Query: 361 TVKDFEKTPNSTLPPAGRPSEEPEPDYEAIQTLNREEEKATLGTNGHHGLVPKENDYESI 420
           TVKDFEKTPNSTLPPAGRPSEEPEPDYEAIQTLNREEEKATLGTNGHHGLVPKENDYESI
Sbjct: 361 TVKDFEKTPNSTLPPAGRPSEEPEPDYEAIQTLNREEEKATLGTNGHHGLVPKENDYESI 420

Query: 421 SDLQQGRDITRL 432
           SDLQQGRDITRL
Sbjct: 421 SDLQQGRDITRL 432


>gi|146229340 mutated in colorectal cancers isoform 1 [Homo sapiens]
          Length = 1019

 Score = 40.0 bits (92), Expect = 0.004
 Identities = 65/284 (22%), Positives = 110/284 (38%), Gaps = 22/284 (7%)

Query: 83  QNGALTNGDILSEDSTLTCMQHYEEVQTSASDLLDSQDSTGKPKCHQSRELPRIPPESAV 142
           Q GA  NG I  +D T   MQ   E++    DL    D++   K            ++++
Sbjct: 79  QLGADENGKISFQDFTRCRMQLVREIRKEEVDLSAKSDNSCTKKLRDRIASWPTSSDNSL 138

Query: 143 DTMLTAR-SVDGDQGLGMEGPYEVLKDSSSQENMVEDCLYETVKEIKEVAAAAHLEKGHS 201
             +  AR S + D G       +V   S+ Q+      L E         AA H     S
Sbjct: 139 GALSAARESWEYDSGARDLQSPDVQSQSALQK------LLEYGGSSLHQQAALHKLLTQS 192

Query: 202 GKAKSTSASKELPGPQTEGKAEFAEYAS--VDRNKKCRQSVNVESILGNSCDPEEEAPPP 259
               ++     L    T   A  A      V+ NK+ +Q+     +L       +     
Sbjct: 193 PHIGNSVGGSYLELANTLHSAALASLKGDIVELNKRLQQTERERDLLEKKLAKAQCEQS- 251

Query: 260 VPVKLLDENENLQEKEGGEAEESATDTTS---ETNKRFSSLSYKSREEDPTLTE--EEIS 314
               L+ E+E++QE+     EE  T+  S   E NK+   L   +  E+   +E   E+S
Sbjct: 252 ---HLMREHEDVQERTTLRYEERITELHSVIAELNKKIDRLQGTTIREEDEYSELRSELS 308

Query: 315 AMYSSVNKPGQLVNKSGQSLTVPESTYTSIQGDPQRSPSSCNDL 358
                VN+  + +++   S+++PE+  T +  D      +C+DL
Sbjct: 309 QSQHEVNEDSRSMDQDQTSVSIPENQSTMVTAD----MDNCSDL 348


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 39.3 bits (90), Expect = 0.007
 Identities = 50/244 (20%), Positives = 98/244 (40%), Gaps = 22/244 (9%)

Query: 162  PYEVLKDSSSQENMVEDCLYETVKEIKEVAAAAHLEKGHSGKAKSTSASKELPGPQTEGK 221
            P  V  +SSSQ+  V   +    K+ +EV   A  EK    K K T + +++P   T  +
Sbjct: 1136 PMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEA--EKVILEKVKETLSMEKIPPMVTTDQ 1193

Query: 222  AEFAEYASVDRNKKCRQSVNVESILGNSCDPEEEAPPPVPVKLLDENENLQEKEGGEAEE 281
             +  E + ++++K                  +E+ P P   KL+ E E ++ +E     E
Sbjct: 1194 KQ--EESKLEKDKASAL--------------QEKKPLPEEKKLIPEEEKIRSEEKKPLLE 1237

Query: 282  SATDTTSETNKRFSSLSYKSREEDPTLTEEEISAMYSSVNKPGQLVNKSGQSLTVPESTY 341
                T  +      + +    E+   L + ++      +   G++  K+ Q    P++  
Sbjct: 1238 EKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLE--GRVAPKTVQEGKQPQTKM 1295

Query: 342  TSI-QGDPQRSPSSCNDLYATVKDFEKTPNSTLPPAGRP-SEEPEPDYEAIQTLNREEEK 399
              +  G PQ  P   +    T+K+  + P +  P    P  E+ E + +   T + ++ K
Sbjct: 1296 EGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPK 1355

Query: 400  ATLG 403
            +  G
Sbjct: 1356 SPQG 1359


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 39.3 bits (90), Expect = 0.007
 Identities = 50/244 (20%), Positives = 98/244 (40%), Gaps = 22/244 (9%)

Query: 162  PYEVLKDSSSQENMVEDCLYETVKEIKEVAAAAHLEKGHSGKAKSTSASKELPGPQTEGK 221
            P  V  +SSSQ+  V   +    K+ +EV   A  EK    K K T + +++P   T  +
Sbjct: 1136 PMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEA--EKVILEKVKETLSMEKIPPMVTTDQ 1193

Query: 222  AEFAEYASVDRNKKCRQSVNVESILGNSCDPEEEAPPPVPVKLLDENENLQEKEGGEAEE 281
             +  E + ++++K                  +E+ P P   KL+ E E ++ +E     E
Sbjct: 1194 KQ--EESKLEKDKASAL--------------QEKKPLPEEKKLIPEEEKIRSEEKKPLLE 1237

Query: 282  SATDTTSETNKRFSSLSYKSREEDPTLTEEEISAMYSSVNKPGQLVNKSGQSLTVPESTY 341
                T  +      + +    E+   L + ++      +   G++  K+ Q    P++  
Sbjct: 1238 EKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLE--GRVAPKTVQEGKQPQTKM 1295

Query: 342  TSI-QGDPQRSPSSCNDLYATVKDFEKTPNSTLPPAGRP-SEEPEPDYEAIQTLNREEEK 399
              +  G PQ  P   +    T+K+  + P +  P    P  E+ E + +   T + ++ K
Sbjct: 1296 EGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPK 1355

Query: 400  ATLG 403
            +  G
Sbjct: 1356 SPQG 1359


>gi|55741677 SET domain containing 1A [Homo sapiens]
          Length = 1707

 Score = 38.5 bits (88), Expect = 0.012
 Identities = 36/128 (28%), Positives = 57/128 (44%), Gaps = 13/128 (10%)

Query: 267  ENENLQEKEGGEAEESATDTTSETNKRFSSLSYKSREEDPTLTEEEISAMYSSVNKPGQL 326
            EN++  + E   +  S++ ++S ++   SS S +S  ED    EEE  A   S + P + 
Sbjct: 1026 ENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDE--EEEERPAALPSASPPPRE 1083

Query: 327  V---NKSGQSLTVPESTYTS-IQGDPQRSPSSCNDLYATVKDFEKTPNSTL----PPAGR 378
            V     +   + VPE    S +   P++  S       T    E  P++ L    PPAG 
Sbjct: 1084 VPVPTPAPVEVPVPERVAGSPVTPLPEQEASPARPAGPTE---ESPPSAPLRPPEPPAGP 1140

Query: 379  PSEEPEPD 386
            P+  P PD
Sbjct: 1141 PAPAPRPD 1148


>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
          Length = 2400

 Score = 38.5 bits (88), Expect = 0.012
 Identities = 48/225 (21%), Positives = 93/225 (41%), Gaps = 12/225 (5%)

Query: 182  ETVKEIKEVAAAAHLEKGHSGKAKSTSASKELPGPQTEGKAEFAEYASVDRNKKCRQSVN 241
            E   E + V A          + ++   S+++  P+ EG+A+  E   V+   +    V 
Sbjct: 1843 EAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQ-PESEDVE-TPEAEWEVQ 1900

Query: 242  VESILGNSCDPEEEAPPPVP-VKLLD-ENENLQEKEGGEA---EESATDTTSETNKRFSS 296
             ES    + + E+EA P    V+ L+ E E+  E EG EA   EE+A +   +T      
Sbjct: 1901 PESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEV 1960

Query: 297  LSYKSREEDPTLTEEEISAMYSSV---NKPGQLVNKSGQSLTVPESTYTSIQGDPQRSPS 353
            +  +  EE+     E++ A+   V      G+   +S + +  PE+     + + +  P 
Sbjct: 1961 IESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPES-EDVEAPEAEGEMQEAEEEAQPE 2019

Query: 354  SCNDLYATVKDFEKTPNSTLPPAGRPSEEPEPDYEAIQTLNREEE 398
            S + + A  K   +          +   + +P+ + ++    EEE
Sbjct: 2020 S-DGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEE 2063



 Score = 31.2 bits (69), Expect = 1.9
 Identities = 55/274 (20%), Positives = 106/274 (38%), Gaps = 26/274 (9%)

Query: 90   GDILSEDSTLTCMQHYEEVQTSASDLLDSQDSTGKPKCHQSRELPRIPPESAVDTMLTAR 149
            GD+  E+    C   +   +  A    + +      +   S  L ++   +  + +    
Sbjct: 1248 GDL--ENQQQCCFPTFLNARACACATNEDEAERDSEEQRASSNLEQLAENTVQEEVQLEE 1305

Query: 150  SVDGDQGLGMEGPYEVLKDSSSQENMVEDCLY-ETVKEIK------EVAAAAHLEK--GH 200
            + +G +G G++     L+++ ++E + E+ +  E  KE +      E A    +E+  G 
Sbjct: 1306 TKEGTEGEGLQEEAVQLEETKTEEGLQEEGVQLEETKETEGEGQQEEEAQLEEIEETGGE 1365

Query: 201  SGKAKSTSASKELPGPQTEGKAEFAEYASVDRNKKCRQSVNVESILGNSCDPEEEAPPPV 260
              + +     +   GP+   + E  E    +       SV+ + +         EA  P 
Sbjct: 1366 GLQEEGVQLEEVKEGPEGGLQGEALEEGLKEEGLPEEGSVHGQEL--------SEASSP- 1416

Query: 261  PVKLLDENENLQEKEGGEAEESATDTTSETNKRFSSLSYKSREEDPTLTEEEI-SAMYSS 319
              K   E++ +QE+E G A  SA    +E  +  +       E DP+ +E +  S +   
Sbjct: 1417 DGKGSQEDDPVQEEEAGRASASAEPCPAEGTEEPTEPPSHLSETDPSASERQSGSQLEPG 1476

Query: 320  VNKPGQLVNKSGQSLTVPESTYTSIQGDPQRSPS 353
            + KP       GQ  T  + T    QG  +RS S
Sbjct: 1477 LEKPPG-ATMMGQEHTQAQPT----QGAAERSSS 1505


>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           9 [Homo sapiens]
          Length = 771

 Score = 38.1 bits (87), Expect = 0.016
 Identities = 57/272 (20%), Positives = 103/272 (37%), Gaps = 38/272 (13%)

Query: 167 KDSSSQENMVEDCLYETVKEIKEVAAAAH--LEKGHSGKAKSTSASKELPGPQTE----- 219
           ++   +E   E+   E  +E +   +A H  + + +S K K++  S+  P P  E     
Sbjct: 178 REQKERERRAEERRKE--REARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELG 235

Query: 220 -GK--------------AEFAEYASVDRNKKCRQSVNVESILGNSCDPEEEAPPPVPVKL 264
            G+              ++  + +  +R     +S + ES  G+  + EEE         
Sbjct: 236 DGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGST 295

Query: 265 LDENENLQEKEGGEAEESATDTTSETNKRFSSLSYKSREEDPTLTEEEISAMYSSVNKPG 324
            +E+E  +E+E  E EE+ +++   + +    +S +   ED    EE  +  +  V    
Sbjct: 296 SEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSED----EERENENHLLVVPES 351

Query: 325 QLVNKSGQSLTVPESTYTSIQGDPQRSPSSCNDLYATVKDFEKTPNSTLPPAGRPSEEPE 384
           +    SG+S    E      +G PQ S  +  D                 P   P+ +  
Sbjct: 352 RFDRDSGESEEAEEEVG---EGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQGC 408

Query: 385 PDYEAIQTLNREEEKATLGTNGHHGLVPKEND 416
              E  Q LNR EE       G +G+V +  D
Sbjct: 409 RSVEEFQCLNRIEE-------GTYGVVYRAKD 433


>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           8 [Homo sapiens]
          Length = 780

 Score = 38.1 bits (87), Expect = 0.016
 Identities = 57/272 (20%), Positives = 103/272 (37%), Gaps = 38/272 (13%)

Query: 167 KDSSSQENMVEDCLYETVKEIKEVAAAAH--LEKGHSGKAKSTSASKELPGPQTE----- 219
           ++   +E   E+   E  +E +   +A H  + + +S K K++  S+  P P  E     
Sbjct: 187 REQKERERRAEERRKE--REARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELG 244

Query: 220 -GK--------------AEFAEYASVDRNKKCRQSVNVESILGNSCDPEEEAPPPVPVKL 264
            G+              ++  + +  +R     +S + ES  G+  + EEE         
Sbjct: 245 DGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGST 304

Query: 265 LDENENLQEKEGGEAEESATDTTSETNKRFSSLSYKSREEDPTLTEEEISAMYSSVNKPG 324
            +E+E  +E+E  E EE+ +++   + +    +S +   ED    EE  +  +  V    
Sbjct: 305 SEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSED----EERENENHLLVVPES 360

Query: 325 QLVNKSGQSLTVPESTYTSIQGDPQRSPSSCNDLYATVKDFEKTPNSTLPPAGRPSEEPE 384
           +    SG+S    E      +G PQ S  +  D                 P   P+ +  
Sbjct: 361 RFDRDSGESEEAEEEVG---EGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQGC 417

Query: 385 PDYEAIQTLNREEEKATLGTNGHHGLVPKEND 416
              E  Q LNR EE       G +G+V +  D
Sbjct: 418 RSVEEFQCLNRIEE-------GTYGVVYRAKD 442


>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           5 [Homo sapiens]
          Length = 748

 Score = 38.1 bits (87), Expect = 0.016
 Identities = 57/272 (20%), Positives = 103/272 (37%), Gaps = 38/272 (13%)

Query: 167 KDSSSQENMVEDCLYETVKEIKEVAAAAH--LEKGHSGKAKSTSASKELPGPQTE----- 219
           ++   +E   E+   E  +E +   +A H  + + +S K K++  S+  P P  E     
Sbjct: 155 REQKERERRAEERRKE--REARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELG 212

Query: 220 -GK--------------AEFAEYASVDRNKKCRQSVNVESILGNSCDPEEEAPPPVPVKL 264
            G+              ++  + +  +R     +S + ES  G+  + EEE         
Sbjct: 213 DGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGST 272

Query: 265 LDENENLQEKEGGEAEESATDTTSETNKRFSSLSYKSREEDPTLTEEEISAMYSSVNKPG 324
            +E+E  +E+E  E EE+ +++   + +    +S +   ED    EE  +  +  V    
Sbjct: 273 SEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSED----EERENENHLLVVPES 328

Query: 325 QLVNKSGQSLTVPESTYTSIQGDPQRSPSSCNDLYATVKDFEKTPNSTLPPAGRPSEEPE 384
           +    SG+S    E      +G PQ S  +  D                 P   P+ +  
Sbjct: 329 RFDRDSGESEEAEEEVG---EGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQGC 385

Query: 385 PDYEAIQTLNREEEKATLGTNGHHGLVPKEND 416
              E  Q LNR EE       G +G+V +  D
Sbjct: 386 RSVEEFQCLNRIEE-------GTYGVVYRAKD 410


>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           4 [Homo sapiens]
          Length = 737

 Score = 38.1 bits (87), Expect = 0.016
 Identities = 57/272 (20%), Positives = 103/272 (37%), Gaps = 38/272 (13%)

Query: 167 KDSSSQENMVEDCLYETVKEIKEVAAAAH--LEKGHSGKAKSTSASKELPGPQTE----- 219
           ++   +E   E+   E  +E +   +A H  + + +S K K++  S+  P P  E     
Sbjct: 144 REQKERERRAEERRKE--REARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELG 201

Query: 220 -GK--------------AEFAEYASVDRNKKCRQSVNVESILGNSCDPEEEAPPPVPVKL 264
            G+              ++  + +  +R     +S + ES  G+  + EEE         
Sbjct: 202 DGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGST 261

Query: 265 LDENENLQEKEGGEAEESATDTTSETNKRFSSLSYKSREEDPTLTEEEISAMYSSVNKPG 324
            +E+E  +E+E  E EE+ +++   + +    +S +   ED    EE  +  +  V    
Sbjct: 262 SEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSED----EERENENHLLVVPES 317

Query: 325 QLVNKSGQSLTVPESTYTSIQGDPQRSPSSCNDLYATVKDFEKTPNSTLPPAGRPSEEPE 384
           +    SG+S    E      +G PQ S  +  D                 P   P+ +  
Sbjct: 318 RFDRDSGESEEAEEEVG---EGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQGC 374

Query: 385 PDYEAIQTLNREEEKATLGTNGHHGLVPKEND 416
              E  Q LNR EE       G +G+V +  D
Sbjct: 375 RSVEEFQCLNRIEE-------GTYGVVYRAKD 399


>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           2 [Homo sapiens]
          Length = 782

 Score = 38.1 bits (87), Expect = 0.016
 Identities = 57/272 (20%), Positives = 103/272 (37%), Gaps = 38/272 (13%)

Query: 167 KDSSSQENMVEDCLYETVKEIKEVAAAAH--LEKGHSGKAKSTSASKELPGPQTE----- 219
           ++   +E   E+   E  +E +   +A H  + + +S K K++  S+  P P  E     
Sbjct: 189 REQKERERRAEERRKE--REARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELG 246

Query: 220 -GK--------------AEFAEYASVDRNKKCRQSVNVESILGNSCDPEEEAPPPVPVKL 264
            G+              ++  + +  +R     +S + ES  G+  + EEE         
Sbjct: 247 DGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGST 306

Query: 265 LDENENLQEKEGGEAEESATDTTSETNKRFSSLSYKSREEDPTLTEEEISAMYSSVNKPG 324
            +E+E  +E+E  E EE+ +++   + +    +S +   ED    EE  +  +  V    
Sbjct: 307 SEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSED----EERENENHLLVVPES 362

Query: 325 QLVNKSGQSLTVPESTYTSIQGDPQRSPSSCNDLYATVKDFEKTPNSTLPPAGRPSEEPE 384
           +    SG+S    E      +G PQ S  +  D                 P   P+ +  
Sbjct: 363 RFDRDSGESEEAEEEVG---EGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQGC 419

Query: 385 PDYEAIQTLNREEEKATLGTNGHHGLVPKEND 416
              E  Q LNR EE       G +G+V +  D
Sbjct: 420 RSVEEFQCLNRIEE-------GTYGVVYRAKD 444


>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
          Length = 770

 Score = 37.4 bits (85), Expect = 0.027
 Identities = 60/279 (21%), Positives = 107/279 (38%), Gaps = 52/279 (18%)

Query: 167 KDSSSQENMVEDCLYETVKEIKEVAAAAH--LEKGHSGKAKSTSASKELPGPQTE----- 219
           ++   +E   E+   E  +E +   +A H  + + +S K K++  S+  P P  E     
Sbjct: 177 REQKERERRAEERRKE--REARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELG 234

Query: 220 -GK--------------AEFAEYASVDRNKKCRQSVNVESILGNSCDPEEEAPPPVPVKL 264
            G+              ++  + +  +R     +S + ES  G+  + EEE         
Sbjct: 235 DGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGST 294

Query: 265 LDENENLQEKEGGEAEESATDTTSETNKRFSSLSYKSREEDPTLTEEEISAMYSSVNKPG 324
            +E+E  +E+E  E EE+ +++   + +    +S +   ED    EE  +  +  V    
Sbjct: 295 SEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSED----EERENENHLLVVPES 350

Query: 325 QLVNKSGQSLTVPESTYTSIQGDPQRSPSSCNDLYATVKDFEKTPNSTLP-------PAG 377
           +    SG+S    E      +G PQ S         T  D+     + LP       P  
Sbjct: 351 RFDRDSGESEEAEEEVG---EGTPQSSA-------LTEGDYVPDSPALLPIELKQELPKY 400

Query: 378 RPSEEPEPDYEAIQTLNREEEKATLGTNGHHGLVPKEND 416
            P+ +     E  Q LNR EE       G +G+V +  D
Sbjct: 401 LPALQGCRSVEEFQCLNRIEE-------GTYGVVYRAKD 432


>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
          Length = 780

 Score = 37.4 bits (85), Expect = 0.027
 Identities = 60/279 (21%), Positives = 107/279 (38%), Gaps = 52/279 (18%)

Query: 167 KDSSSQENMVEDCLYETVKEIKEVAAAAH--LEKGHSGKAKSTSASKELPGPQTE----- 219
           ++   +E   E+   E  +E +   +A H  + + +S K K++  S+  P P  E     
Sbjct: 187 REQKERERRAEERRKE--REARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELG 244

Query: 220 -GK--------------AEFAEYASVDRNKKCRQSVNVESILGNSCDPEEEAPPPVPVKL 264
            G+              ++  + +  +R     +S + ES  G+  + EEE         
Sbjct: 245 DGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGST 304

Query: 265 LDENENLQEKEGGEAEESATDTTSETNKRFSSLSYKSREEDPTLTEEEISAMYSSVNKPG 324
            +E+E  +E+E  E EE+ +++   + +    +S +   ED    EE  +  +  V    
Sbjct: 305 SEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSED----EERENENHLLVVPES 360

Query: 325 QLVNKSGQSLTVPESTYTSIQGDPQRSPSSCNDLYATVKDFEKTPNSTLP-------PAG 377
           +    SG+S    E      +G PQ S         T  D+     + LP       P  
Sbjct: 361 RFDRDSGESEEAEEEVG---EGTPQSSA-------LTEGDYVPDSPALLPIELKQELPKY 410

Query: 378 RPSEEPEPDYEAIQTLNREEEKATLGTNGHHGLVPKEND 416
            P+ +     E  Q LNR EE       G +G+V +  D
Sbjct: 411 LPALQGCRSVEEFQCLNRIEE-------GTYGVVYRAKD 442


>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
          Length = 2454

 Score = 37.4 bits (85), Expect = 0.027
 Identities = 77/379 (20%), Positives = 135/379 (35%), Gaps = 53/379 (13%)

Query: 37   CSSCDREKKPRQHSGDHENLMNVPSDKEMFSRSVTSLATDAPASSEQN-------GALTN 89
            C+S D+  K R    +  NL +  + KE+ S S +S   DA  SSE N        +   
Sbjct: 1084 CNSSDKRLK-RIELRERRNLSSKRNTKEIQSGSSSS---DAEESSEDNKKKKQRTSSKKK 1139

Query: 90   GDILSEDS-----TLTCMQHYEEVQTSASDLLDS-QDSTGKPKCHQSRELPRIPPESAVD 143
              I+ E       T T  +  +   +S+SD+ D  Q+S G+    + +  P +     + 
Sbjct: 1140 AVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKP-VTENLVLS 1198

Query: 144  TMLTARSVDGDQGLGMEGPYEVLKDSSSQE---NMVEDCLYETVK-EIKEVAAAAHLEKG 199
            +        GD+ L    P  V  D    +    + +  L E +K  +      +  ++ 
Sbjct: 1199 SHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEP 1258

Query: 200  HSGKAKSTSASKELPGPQTEGKAEFAEYASVDRNKKCRQSVNVESILGNSCDPEEEAPPP 259
              GK ++   ++E PG                 +++ +  VN ES      D EE   P 
Sbjct: 1259 EEGKKRTGKQNEENPG-----------------DEEAKNQVNSES----DSDSEESKKPR 1297

Query: 260  VPVKLLDENENLQEKEGGEAEESATDTTSETNKRFSSLSYKSREEDPTLTEEEISAMYSS 319
               +LL     + + E GE +++      E   R          ED    E  +S   S 
Sbjct: 1298 YRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSE 1357

Query: 320  VNKPGQLVNKSGQSLTVPESTYTSIQGDPQRSPSSCNDLYATVKDFEKTPNSTLPPAGRP 379
                 +   +S +   + E+  +  Q   +R           +K  E + +     +   
Sbjct: 1358 SEDEQRPRTRSAKKAELEENQRSYKQKKKRR----------RIKVQEDSSSENKSNSEEE 1407

Query: 380  SEEPEPDYEAIQTLNREEE 398
             EE E + E  +    EEE
Sbjct: 1408 EEEKEEEEEEEEEEEEEEE 1426


>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
          Length = 2492

 Score = 37.4 bits (85), Expect = 0.027
 Identities = 77/379 (20%), Positives = 135/379 (35%), Gaps = 53/379 (13%)

Query: 37   CSSCDREKKPRQHSGDHENLMNVPSDKEMFSRSVTSLATDAPASSEQN-------GALTN 89
            C+S D+  K R    +  NL +  + KE+ S S +S   DA  SSE N        +   
Sbjct: 1122 CNSSDKRLK-RIELRERRNLSSKRNTKEIQSGSSSS---DAEESSEDNKKKKQRTSSKKK 1177

Query: 90   GDILSEDS-----TLTCMQHYEEVQTSASDLLDS-QDSTGKPKCHQSRELPRIPPESAVD 143
              I+ E       T T  +  +   +S+SD+ D  Q+S G+    + +  P +     + 
Sbjct: 1178 AVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKP-VTENLVLS 1236

Query: 144  TMLTARSVDGDQGLGMEGPYEVLKDSSSQE---NMVEDCLYETVK-EIKEVAAAAHLEKG 199
            +        GD+ L    P  V  D    +    + +  L E +K  +      +  ++ 
Sbjct: 1237 SHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEP 1296

Query: 200  HSGKAKSTSASKELPGPQTEGKAEFAEYASVDRNKKCRQSVNVESILGNSCDPEEEAPPP 259
              GK ++   ++E PG                 +++ +  VN ES      D EE   P 
Sbjct: 1297 EEGKKRTGKQNEENPG-----------------DEEAKNQVNSES----DSDSEESKKPR 1335

Query: 260  VPVKLLDENENLQEKEGGEAEESATDTTSETNKRFSSLSYKSREEDPTLTEEEISAMYSS 319
               +LL     + + E GE +++      E   R          ED    E  +S   S 
Sbjct: 1336 YRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSE 1395

Query: 320  VNKPGQLVNKSGQSLTVPESTYTSIQGDPQRSPSSCNDLYATVKDFEKTPNSTLPPAGRP 379
                 +   +S +   + E+  +  Q   +R           +K  E + +     +   
Sbjct: 1396 SEDEQRPRTRSAKKAELEENQRSYKQKKKRR----------RIKVQEDSSSENKSNSEEE 1445

Query: 380  SEEPEPDYEAIQTLNREEE 398
             EE E + E  +    EEE
Sbjct: 1446 EEEKEEEEEEEEEEEEEEE 1464


>gi|38372901 Sp1 transcription factor isoform a [Homo sapiens]
          Length = 785

 Score = 37.0 bits (84), Expect = 0.035
 Identities = 36/156 (23%), Positives = 63/156 (40%), Gaps = 21/156 (13%)

Query: 33  LIFLCSSCDREKKPRQHSGDHENLMNVPSDKEMFSRS------------VTSLATDAPAS 80
           L  L ++C R + P ++S + +         E+   +            ++S +   P S
Sbjct: 61  LALLAATCSRIESPNENSNNSQGPSQSGGTGELDLTATQLSQGANGWQIISSSSGATPTS 120

Query: 81  SEQNGALTNGDILSEDSTLTCMQHYEEVQTSASDLLDSQDSTGKPKCHQSRELPRIPPES 140
            EQ+G+ TNG   SE S    +   + V  +A +L + Q  TG         LP + P  
Sbjct: 121 KEQSGSSTNGSNGSESSKNRTVSGGQYVVAAAPNLQNQQVLTG---------LPGVMPNI 171

Query: 141 AVDTMLTARSVDGDQGLGMEGPYEVLKDSSSQENMV 176
               +   ++VDG Q        +V +D S Q  ++
Sbjct: 172 QYQVIPQFQTVDGQQLQFAATGAQVQQDGSGQIQII 207


>gi|218751903 Sp1 transcription factor isoform b [Homo sapiens]
          Length = 778

 Score = 37.0 bits (84), Expect = 0.035
 Identities = 36/156 (23%), Positives = 63/156 (40%), Gaps = 21/156 (13%)

Query: 33  LIFLCSSCDREKKPRQHSGDHENLMNVPSDKEMFSRS------------VTSLATDAPAS 80
           L  L ++C R + P ++S + +         E+   +            ++S +   P S
Sbjct: 54  LALLAATCSRIESPNENSNNSQGPSQSGGTGELDLTATQLSQGANGWQIISSSSGATPTS 113

Query: 81  SEQNGALTNGDILSEDSTLTCMQHYEEVQTSASDLLDSQDSTGKPKCHQSRELPRIPPES 140
            EQ+G+ TNG   SE S    +   + V  +A +L + Q  TG         LP + P  
Sbjct: 114 KEQSGSSTNGSNGSESSKNRTVSGGQYVVAAAPNLQNQQVLTG---------LPGVMPNI 164

Query: 141 AVDTMLTARSVDGDQGLGMEGPYEVLKDSSSQENMV 176
               +   ++VDG Q        +V +D S Q  ++
Sbjct: 165 QYQVIPQFQTVDGQQLQFAATGAQVQQDGSGQIQII 200


>gi|4505129 mutated in colorectal cancers isoform 2 [Homo sapiens]
          Length = 829

 Score = 37.0 bits (84), Expect = 0.035
 Identities = 27/100 (27%), Positives = 50/100 (50%), Gaps = 9/100 (9%)

Query: 264 LLDENENLQEKEGGEAEESATDTTS---ETNKRFSSLSYKSREEDPTLTE--EEISAMYS 318
           L+ E+E++QE+     EE  T+  S   E NK+   L   +  E+   +E   E+S    
Sbjct: 63  LMREHEDVQERTTLRYEERITELHSVIAELNKKIDRLQGTTIREEDEYSELRSELSQSQH 122

Query: 319 SVNKPGQLVNKSGQSLTVPESTYTSIQGDPQRSPSSCNDL 358
            VN+  + +++   S+++PE+  T +  D      +C+DL
Sbjct: 123 EVNEDSRSMDQDQTSVSIPENQSTMVTAD----MDNCSDL 158


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 36.6 bits (83), Expect = 0.045
 Identities = 57/381 (14%), Positives = 134/381 (35%), Gaps = 7/381 (1%)

Query: 38   SSCDREKKPRQHSGDHENLMNVPSDKEMFSRSVTSLATDAPASSEQNGALTNGDILSEDS 97
            SS   +     +S D+ N  +  +  +    S +S ++D+  SS+ + +  + D  S DS
Sbjct: 917  SSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDS 976

Query: 98   TLTCMQHYEEVQTSASDLLDSQDSTGKPKCHQSRELPRIPPESAVDTMLTARSVDGDQGL 157
            + +         + +SD  DS DS+       S +       ++ D+  ++ S +     
Sbjct: 977  SDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD--SSDSSNSSDSSNSSDSSNSSDSS 1034

Query: 158  GMEGPYEVLKDSSSQENMVEDCLYETVKEIKEVAAAAHLEKGHSGKAKSTSASKELPGPQ 217
                  +    S S ++       ++        ++   +   S  +  +S S +     
Sbjct: 1035 DSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSS 1094

Query: 218  TEGKAEFAEYASVDRNKKCRQSVNVESILGNSCDPEEEAPPPVPVKLLDENENLQEKEGG 277
                +  +  +S   +       +  S   +S D  + +         D +++ +  +  
Sbjct: 1095 DSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSS 1154

Query: 278  EAEESATDTTSETNKRFSSLSYKSREEDPTLTEEEISAMYSSVNKPGQLVNKSGQSLTVP 337
            ++ +S+  + S  +   S  S  S   D + + +   +  SS +      + S  S    
Sbjct: 1155 DSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1214

Query: 338  ESTYTSIQGDPQRSPSSCNDLYATVKDFEKTPNSTLPPAGRPSEEPEPDYEAIQTLNREE 397
            +S+ +S   D   S  S         D   + +S+       S +     ++    N E 
Sbjct: 1215 DSSDSSDSSDSSDSSDSNES-----SDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDES 1269

Query: 398  EKATLGTNGHHGLVPKENDYE 418
            +  +   NG++     ++D E
Sbjct: 1270 DSQSKSGNGNNNGSDSDSDSE 1290



 Score = 32.7 bits (73), Expect = 0.66
 Identities = 55/313 (17%), Positives = 117/313 (37%), Gaps = 22/313 (7%)

Query: 50  SGDHENLMNVPSDKEMFSRSVTSLATDAPASSEQNGALTNGDILSEDSTLTCMQHYEEVQ 109
           S D  +  +  S  +  + S +S ++D+  SSE + +  + D  S DS+ +   +  +  
Sbjct: 668 SSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSD 727

Query: 110 TSASDLLDSQDSTGKPKCHQSRELPRIPPES-AVDTMLTARSVDGDQGLGMEGPYEVLKD 168
           +S S   DS DS+       S +       S + D+  ++ S D               D
Sbjct: 728 SSNSS--DSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDS----------SD 775

Query: 169 SSSQENMVEDCLYETVKEIKEVAAAAHLEKGHSGKAKSTSASKELPGPQTEGKAEFAEYA 228
           SS   N  +        +  + + ++  +  +S  +  +S S +     +   +  ++  
Sbjct: 776 SSDSSNSSDSNDSSNSSDSSDSSNSS--DSSNSSDSSDSSDSSDSDSSNSSDSSNSSD-- 831

Query: 229 SVDRNKKCRQSVNVESILGNSCDPEEEAPPPVPVKLLDENENLQEKEGGEAEES-----A 283
           S D +     S + +S  G+  D    +         D +++    +  ++ +S     +
Sbjct: 832 SSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNS 891

Query: 284 TDTTSETNKRFSSLSYKSREEDPTLTEEEISAMYSSVNKPGQLVNKSGQSLTVPESTYTS 343
           +D++  +N   S  S  S   D + +     +  SS +      + S  S    +S+ +S
Sbjct: 892 SDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSS 951

Query: 344 IQGDPQRSPSSCN 356
              D   S  S N
Sbjct: 952 NSSDSSNSSDSSN 964



 Score = 32.7 bits (73), Expect = 0.66
 Identities = 52/317 (16%), Positives = 110/317 (34%), Gaps = 11/317 (3%)

Query: 38   SSCDREKKPRQHSGDHENLMNVPSDKEMFSRSVTSLATDAPASSEQNGALTNGDILSEDS 97
            SS   +      S D  N  +          S +S ++D+  SS+ + +  + D  S +S
Sbjct: 764  SSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNS 823

Query: 98   TLTCMQHYEEVQTSASDLLDSQDSTGKPKCHQSRELPRIPPESAVDTMLTARSVDGDQGL 157
            + +         +++SD  DS DS+       S          + D+  ++ S D     
Sbjct: 824  SDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDS- 882

Query: 158  GMEGPYEVLKDSSSQENMVEDCLYETVKEIKEVAAAAHLEKGHSGKAKSTSASKELPGPQ 217
                      DSS   N  +    ++        ++   +   S  +   S S +     
Sbjct: 883  SDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSS 942

Query: 218  TEGKAEFAEYASVDRNKKCRQSVNVESILGNSCDPEEEAPPPVPVKLLDENENLQEKEGG 277
                +  +  +S D +     S + +S   NS D  + +         + +++    +  
Sbjct: 943  DSSDSSDSSNSS-DSSNSSDSSNSSDSSDSNSSDSSDSS---------NSSDSSDSSDSS 992

Query: 278  EAEESATDTTSETNKRFSSLSYKSREEDPTLTEEEISAMYSSVNKPGQLVNKSGQSLTVP 337
            ++ +S+  + S  +   S  S  S   D + + +  ++  SS +      + S  S    
Sbjct: 993  DSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1052

Query: 338  ESTYTSIQGDPQRSPSS 354
            +S+ +S   D   S  S
Sbjct: 1053 DSSNSSDSSDSSDSSDS 1069


>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
           sapiens]
          Length = 699

 Score = 36.6 bits (83), Expect = 0.045
 Identities = 43/225 (19%), Positives = 84/225 (37%), Gaps = 7/225 (3%)

Query: 190 VAAAAHLEKGHSGKAKSTSASKELPGPQTEGKAEFAEYASVDRNKKCRQSVNVESILGNS 249
           VA  A  +   S    S+   +E+ GP  +  A  A+   +   K   ++    S   +S
Sbjct: 74  VAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASESSSSEESS 133

Query: 250 CDPEEEAPPPVPVKLLDENENLQEKEGGEAEESATDTTSETNKRFSSLSYKSREEDPTLT 309
            D +EE     PV+   +    Q K      + A  + S+++   SS     + + P +T
Sbjct: 134 DDDDEEDQKKQPVQ---KGVKPQAKAAKAPPKKAKSSDSDSDS--SSEDEPPKNQKPKIT 188

Query: 310 EEEISAMYSSVNKPGQLVNK--SGQSLTVPESTYTSIQGDPQRSPSSCNDLYATVKDFEK 367
              + A   +  KP +   K  +G++ +   S+ +S   D      +      TV   + 
Sbjct: 189 PVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQV 248

Query: 368 TPNSTLPPAGRPSEEPEPDYEAIQTLNREEEKATLGTNGHHGLVP 412
              + +  A  P+ +     ++      E++K      G +  VP
Sbjct: 249 VAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVP 293



 Score = 35.0 bits (79), Expect = 0.13
 Identities = 76/374 (20%), Positives = 136/374 (36%), Gaps = 46/374 (12%)

Query: 59  VPSDKEMFSRSVTSLATDAPASSEQNGALT------NGDILSEDSTLTCMQHYEEVQTSA 112
           + + K   S S +S ++ +  S E+  A T         ++++           +  +S 
Sbjct: 209 IANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSE 268

Query: 113 SDLLDSQDSTGKPKCHQSRELPRIPPESAVDTMLTARSVDGDQGLGMEGPYEVLKDSSSQ 172
               D ++   KP  ++      +PP SA     +  +    + +  + P E  +DSS +
Sbjct: 269 DSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDE 328

Query: 173 ENMVEDCLYETVKEIKEVAAAAHLEKGHSGKAKSTSASKELPGPQTEGKAEFAEYASVDR 232
            +   +   E  K   +   +    K    K  + S+S       +E     ++ A   +
Sbjct: 329 SDSSSE---EEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTK 385

Query: 233 NKKCRQSVNVESILGNSCDPEEEAPPPVPV----KLL----DENENLQEKEGGEAEES-- 282
           N     S N  ++   S   +  A P  PV    KLL    D + + +E    E E++  
Sbjct: 386 N-----SSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKK 440

Query: 283 --ATDTTSETNKRFSSLSYK----------SREEDPTLTEEEISAMYSSVNKPGQLVNKS 330
             AT     T K   SL  K          S  +  +  EEE     S+V K  Q V   
Sbjct: 441 MVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGG 500

Query: 331 GQSLTVPESTYTSIQGDPQRSPSSCNDLYATVKDFEK-----TPNSTLPPAGRPSEEPEP 385
                 P    ++ +G  + S SS +D  ++ ++ EK     +P    P A   S     
Sbjct: 501 ----AAPSKPASAKKGKAESSNSSSSD-DSSEEEEEKLKGKGSPRPQAPKANGTSALTAQ 555

Query: 386 DYEAIQTLNREEEK 399
           + +A +    EEE+
Sbjct: 556 NGKAAKNSEEEEEE 569


>gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           3 [Homo sapiens]
          Length = 526

 Score = 36.6 bits (83), Expect = 0.045
 Identities = 43/195 (22%), Positives = 75/195 (38%), Gaps = 14/195 (7%)

Query: 222 AEFAEYASVDRNKKCRQSVNVESILGNSCDPEEEAPPPVPVKLLDENENLQEKEGGEAEE 281
           ++  + +  +R     +S + ES  G+  + EEE          +E+E  +E+E  E EE
Sbjct: 8   SDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEE 67

Query: 282 SATDTTSETNKRFSSLSYKSREEDPTLTEEEISAMYSSVNKPGQLVNKSGQSLTVPESTY 341
           + +++   + +    +S +   ED    EE  +  +  V    +    SG+S    E   
Sbjct: 68  TGSNSEEASEQSAEEVSEEEMSED----EERENENHLLVVPESRFDRDSGESEEAEEEVG 123

Query: 342 TSIQGDPQRSPSSCNDLYATVKDFEKTPNSTLPPAGRPSEEPEPDYEAIQTLNREEEKAT 401
              +G PQ S  +  D                 P   P+ +     E  Q LNR EE   
Sbjct: 124 ---EGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQGCRSVEEFQCLNRIEE--- 177

Query: 402 LGTNGHHGLVPKEND 416
               G +G+V +  D
Sbjct: 178 ----GTYGVVYRAKD 188


>gi|23111062 splicing factor, arginine/serine-rich 8 [Homo sapiens]
          Length = 951

 Score = 36.2 bits (82), Expect = 0.059
 Identities = 60/238 (25%), Positives = 96/238 (40%), Gaps = 46/238 (19%)

Query: 153 GDQGLGMEGPYEVLKDSSSQE--NMVEDCLYETVKEIKEVAAAAHLEKGHSGKAKSTSAS 210
           GD    +  P E   DS+ ++  +  ED   E   E+   A         SG  K  S+S
Sbjct: 512 GDSMQAVSAPEEAPTDSAPEKPSDAGEDGAPEDAAEVGARAG--------SGGKKEASSS 563

Query: 211 KELPGPQTEGKAEFAEYASVDRNKKCRQSVNVESILGNSCDPEEEAPPPVPVKLLDENEN 270
           K +P    +GK   A +A +    K ++         N   P E+      VKL D++++
Sbjct: 564 KTVP----DGKLVKASFAPISFAIKAKE---------NDLLPLEKNR----VKLDDDSDD 606

Query: 271 LQE-KEGGEAEESATDTTSETNKRFSSLSYKSREEDPTLTEEEISAMYSSVNKPGQLVNK 329
            +E KEG E+  SA +T    N   +       E+ P LT+EE+ A  +      +L   
Sbjct: 607 DEESKEGQESSSSAANT----NPAVAPPCVVVEEKKPQLTQEELEAKQAKQKLEDRLAAA 662

Query: 330 SGQSL--TVPESTYTSIQGDPQRSPSSCNDLYATVKDFEKTPNSTLP--PAGRPSEEP 383
           + + L     ES    +Q + +R  +           F +T  + LP   AG+  E P
Sbjct: 663 AREKLAQASKESKEKQLQAERKRKAAL----------FLQTLKNPLPEAEAGKIEESP 710


>gi|113415504 PREDICTED: similar to ribonucleic acid binding protein
           S1 [Homo sapiens]
          Length = 305

 Score = 35.8 bits (81), Expect = 0.078
 Identities = 48/171 (28%), Positives = 67/171 (39%), Gaps = 13/171 (7%)

Query: 240 VNVESILG---NSCDPEEEAPPPVPVK-LLDENENLQEKEGGEAEESATDTTS--ETNKR 293
           V  +S+LG   N+      AP P   K   DE    + K+ G  +ES+       +T KR
Sbjct: 6   VKKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKR 65

Query: 294 FS----SLSYKSREEDPTLTEEEISAMYSSVNKPGQLVNKSGQSLTVPESTYTSIQGDPQ 349
            S    S S +SR    + +    S   SS +      ++SG S T   S+ +S  G P 
Sbjct: 66  HSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSP- 124

Query: 350 RSPS-SCNDLYATVKDFEKTPNSTLPPAGRPSEEPEPDYEAIQTLNREEEK 399
            SPS   +D     +   K P        R S  P+P    I  L R   K
Sbjct: 125 -SPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRNVTK 174


>gi|169166499 PREDICTED: similar to ribonucleic acid binding protein
           S1 [Homo sapiens]
          Length = 305

 Score = 35.8 bits (81), Expect = 0.078
 Identities = 48/171 (28%), Positives = 67/171 (39%), Gaps = 13/171 (7%)

Query: 240 VNVESILG---NSCDPEEEAPPPVPVK-LLDENENLQEKEGGEAEESATDTTS--ETNKR 293
           V  +S+LG   N+      AP P   K   DE    + K+ G  +ES+       +T KR
Sbjct: 6   VKKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKR 65

Query: 294 FS----SLSYKSREEDPTLTEEEISAMYSSVNKPGQLVNKSGQSLTVPESTYTSIQGDPQ 349
            S    S S +SR    + +    S   SS +      ++SG S T   S+ +S  G P 
Sbjct: 66  HSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSP- 124

Query: 350 RSPS-SCNDLYATVKDFEKTPNSTLPPAGRPSEEPEPDYEAIQTLNREEEK 399
            SPS   +D     +   K P        R S  P+P    I  L R   K
Sbjct: 125 -SPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRNVTK 174


>gi|113415498 PREDICTED: similar to ribonucleic acid binding protein
           S1 [Homo sapiens]
          Length = 305

 Score = 35.8 bits (81), Expect = 0.078
 Identities = 48/171 (28%), Positives = 67/171 (39%), Gaps = 13/171 (7%)

Query: 240 VNVESILG---NSCDPEEEAPPPVPVK-LLDENENLQEKEGGEAEESATDTTS--ETNKR 293
           V  +S+LG   N+      AP P   K   DE    + K+ G  +ES+       +T KR
Sbjct: 6   VKKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKR 65

Query: 294 FS----SLSYKSREEDPTLTEEEISAMYSSVNKPGQLVNKSGQSLTVPESTYTSIQGDPQ 349
            S    S S +SR    + +    S   SS +      ++SG S T   S+ +S  G P 
Sbjct: 66  HSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSP- 124

Query: 350 RSPS-SCNDLYATVKDFEKTPNSTLPPAGRPSEEPEPDYEAIQTLNREEEK 399
            SPS   +D     +   K P        R S  P+P    I  L R   K
Sbjct: 125 -SPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRNVTK 174


>gi|88973230 PREDICTED: similar to ribonucleic acid binding protein
           S1 isoform 3 [Homo sapiens]
          Length = 305

 Score = 35.8 bits (81), Expect = 0.078
 Identities = 48/171 (28%), Positives = 67/171 (39%), Gaps = 13/171 (7%)

Query: 240 VNVESILG---NSCDPEEEAPPPVPVK-LLDENENLQEKEGGEAEESATDTTS--ETNKR 293
           V  +S+LG   N+      AP P   K   DE    + K+ G  +ES+       +T KR
Sbjct: 6   VKKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKR 65

Query: 294 FS----SLSYKSREEDPTLTEEEISAMYSSVNKPGQLVNKSGQSLTVPESTYTSIQGDPQ 349
            S    S S +SR    + +    S   SS +      ++SG S T   S+ +S  G P 
Sbjct: 66  HSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSP- 124

Query: 350 RSPS-SCNDLYATVKDFEKTPNSTLPPAGRPSEEPEPDYEAIQTLNREEEK 399
            SPS   +D     +   K P        R S  P+P    I  L R   K
Sbjct: 125 -SPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRNVTK 174


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 35.8 bits (81), Expect = 0.078
 Identities = 32/148 (21%), Positives = 59/148 (39%), Gaps = 16/148 (10%)

Query: 164 EVLKDSSSQENMVEDCLYETVKEIKEVAAAAHLEKGHSGKAKSTSASKELPGPQTEGKAE 223
           E  KDS  +E   ++     V+E KE A     E     K +     K++P P+ E  A+
Sbjct: 854 EEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAK 913

Query: 224 FAEYASVDRNKKCRQSVNVESILGNSCDPEEEAPPPVPVKLLDENENLQEKEGGEAEESA 283
                 V  + K ++   V     +    +E + P    +   E ++ +E++  + EE  
Sbjct: 914 ----VEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKP 969

Query: 284 TDTTSETNKRFSSLSYKSREEDPTLTEE 311
                           K++E+D TL++E
Sbjct: 970 KTEA------------KAKEDDKTLSKE 985


>gi|23111036 sorting nexin 1 isoform c [Homo sapiens]
          Length = 474

 Score = 35.4 bits (80), Expect = 0.10
 Identities = 34/152 (22%), Positives = 56/152 (36%), Gaps = 14/152 (9%)

Query: 247 GNSCDPEEEAPPPVPVKLLDENENLQEKEGGEAEESATDTTSETNKRFSSLSYKSREEDP 306
           G  C   E  PPP P       E   E   G +E  A D+ +E    F+  +  S+ + P
Sbjct: 5   GGGCSASERLPPPFPGL-----EPESEGAAGGSEPEAGDSDTEGEDIFTGAAVVSKHQSP 59

Query: 307 TLTEEEISAMYSSVNKPGQLVNKSGQSLTVPESTYTSIQGDPQRSPSSCNDLYATVKDFE 366
            +T   +     S  K   +  +  Q    P+  +     +     +  N      K   
Sbjct: 60  KITTSLLPINNGS--KENGIHEEQDQE---PQDLFADATVELSLDSTQNNQK----KVLA 110

Query: 367 KTPNSTLPPAGRPSEEPEPDYEAIQTLNREEE 398
           KT  S  P     S +P+P YE ++   +E++
Sbjct: 111 KTLISLPPQEATNSSKPQPTYEELEEEEQEDQ 142


>gi|23111034 sorting nexin 1 isoform a [Homo sapiens]
          Length = 522

 Score = 35.4 bits (80), Expect = 0.10
 Identities = 34/152 (22%), Positives = 56/152 (36%), Gaps = 14/152 (9%)

Query: 247 GNSCDPEEEAPPPVPVKLLDENENLQEKEGGEAEESATDTTSETNKRFSSLSYKSREEDP 306
           G  C   E  PPP P       E   E   G +E  A D+ +E    F+  +  S+ + P
Sbjct: 5   GGGCSASERLPPPFPGL-----EPESEGAAGGSEPEAGDSDTEGEDIFTGAAVVSKHQSP 59

Query: 307 TLTEEEISAMYSSVNKPGQLVNKSGQSLTVPESTYTSIQGDPQRSPSSCNDLYATVKDFE 366
            +T   +     S  K   +  +  Q    P+  +     +     +  N      K   
Sbjct: 60  KITTSLLPINNGS--KENGIHEEQDQE---PQDLFADATVELSLDSTQNNQK----KVLA 110

Query: 367 KTPNSTLPPAGRPSEEPEPDYEAIQTLNREEE 398
           KT  S  P     S +P+P YE ++   +E++
Sbjct: 111 KTLISLPPQEATNSSKPQPTYEELEEEEQEDQ 142


>gi|42518068 trans-golgi network protein 2 [Homo sapiens]
          Length = 437

 Score = 35.4 bits (80), Expect = 0.10
 Identities = 38/192 (19%), Positives = 68/192 (35%), Gaps = 12/192 (6%)

Query: 245 ILGNSCDPEEEAPPPVPVKLLDENENLQEKEGGEAEESATDTTSETNKRFSSLSYKSREE 304
           +L      +EEA        +  + +L ++ GG  +      T + +   SS   ++ E+
Sbjct: 20  LLATESVKQEEAGVRPSAGNVSTHPSLSQRPGGSTKSHPEPQTPKDSPSKSSAEAQTPED 79

Query: 305 DPTLTEEEISAMYSSVNKPGQ-------LVNKSGQSLTVPESTYTSIQGDPQRSPSSCND 357
            P  +  E      S NK G          +KSG      + + +    + Q    S   
Sbjct: 80  TPNKSGAEAKTQKDSSNKSGAEAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDSTGK 139

Query: 358 LYATVKDFEKTPNSTLPPAGRPSEEPEPDYEAIQTLNREEEKATLGTNGHHGLVPKENDY 417
             A  +  E +PN +   A    + P       QT      K     +G  G  PK+   
Sbjct: 140 SGAEAQTPEDSPNRSGAEAKTQKDSPSKSGSEAQTTKDVPNK-----SGADGQTPKDGSS 194

Query: 418 ESISDLQQGRDI 429
           +S ++ Q  +D+
Sbjct: 195 KSGAEDQTPKDV 206


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.305    0.124    0.345 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,697,607
Number of Sequences: 37866
Number of extensions: 929902
Number of successful extensions: 3243
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 180
Number of HSP's that attempted gapping in prelim test: 3020
Number of HSP's gapped (non-prelim): 329
length of query: 432
length of database: 18,247,518
effective HSP length: 105
effective length of query: 327
effective length of database: 14,271,588
effective search space: 4666809276
effective search space used: 4666809276
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press