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Search of human proteins with 63054848
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|63054848 coiled-coil domain containing 34 isoform 1 [Homo
sapiens]
(373 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|63054848 coiled-coil domain containing 34 isoform 1 [Homo sap... 766 0.0
gi|18087817 coiled-coil domain containing 34 isoform 2 [Homo sap... 417 e-117
gi|88759339 aster-associated protein [Homo sapiens] 88 1e-17
gi|148746195 trichohyalin [Homo sapiens] 75 7e-14
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 75 1e-13
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 74 2e-13
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 72 6e-13
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 72 1e-12
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 71 1e-12
gi|221219020 NYD-SP11 protein [Homo sapiens] 69 5e-12
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 69 5e-12
gi|22035602 mitogen-activated protein kinase kinase kinase kinas... 69 7e-12
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 69 9e-12
gi|22758136 MAP7 domain containing 2 [Homo sapiens] 68 1e-11
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 68 2e-11
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 68 2e-11
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 68 2e-11
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 68 2e-11
gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo ... 68 2e-11
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 68 2e-11
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 67 2e-11
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 67 2e-11
gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens] 66 4e-11
gi|27436917 misshapen/NIK-related kinase isoform 3 [Homo sapiens] 66 4e-11
gi|7657335 misshapen/NIK-related kinase isoform 1 [Homo sapiens] 66 4e-11
gi|22035606 mitogen-activated protein kinase kinase kinase kinas... 66 4e-11
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 65 8e-11
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 65 8e-11
gi|22035604 mitogen-activated protein kinase kinase kinase kinas... 65 1e-10
gi|239747891 PREDICTED: hypothetical protein [Homo sapiens] 65 1e-10
>gi|63054848 coiled-coil domain containing 34 isoform 1 [Homo
sapiens]
Length = 373
Score = 766 bits (1977), Expect = 0.0
Identities = 373/373 (100%), Positives = 373/373 (100%)
Query: 1 MWAAGRWGPTFPSSYAGFSADCRPRSRPSSDSCSVPMTGARGQGLEVVRSPSPPLPLSCS 60
MWAAGRWGPTFPSSYAGFSADCRPRSRPSSDSCSVPMTGARGQGLEVVRSPSPPLPLSCS
Sbjct: 1 MWAAGRWGPTFPSSYAGFSADCRPRSRPSSDSCSVPMTGARGQGLEVVRSPSPPLPLSCS 60
Query: 61 NSTRSLLSPLGHQSFQFDEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCAS 120
NSTRSLLSPLGHQSFQFDEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCAS
Sbjct: 61 NSTRSLLSPLGHQSFQFDEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCAS 120
Query: 121 TQVESENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEE 180
TQVESENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEE
Sbjct: 121 TQVESENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEE 180
Query: 181 REKRKIIAEEKHKEWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWL 240
REKRKIIAEEKHKEWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWL
Sbjct: 181 REKRKIIAEEKHKEWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWL 240
Query: 241 KKKNAEECERKKKEKEKEKQQQAEIQEKKEIAEKKFQEWLENAKHKPRPAAKSYGYANGK 300
KKKNAEECERKKKEKEKEKQQQAEIQEKKEIAEKKFQEWLENAKHKPRPAAKSYGYANGK
Sbjct: 241 KKKNAEECERKKKEKEKEKQQQAEIQEKKEIAEKKFQEWLENAKHKPRPAAKSYGYANGK 300
Query: 301 LTGFYSGNSYPEPAFYNPIPWKPIHMPPPKEAKDLSGRKSKRPVISQPHKSSSLVIHKAR 360
LTGFYSGNSYPEPAFYNPIPWKPIHMPPPKEAKDLSGRKSKRPVISQPHKSSSLVIHKAR
Sbjct: 301 LTGFYSGNSYPEPAFYNPIPWKPIHMPPPKEAKDLSGRKSKRPVISQPHKSSSLVIHKAR 360
Query: 361 SNLCLGTLCRIQR 373
SNLCLGTLCRIQR
Sbjct: 361 SNLCLGTLCRIQR 373
>gi|18087817 coiled-coil domain containing 34 isoform 2 [Homo
sapiens]
Length = 229
Score = 417 bits (1073), Expect = e-117
Identities = 203/205 (99%), Positives = 204/205 (99%)
Query: 1 MWAAGRWGPTFPSSYAGFSADCRPRSRPSSDSCSVPMTGARGQGLEVVRSPSPPLPLSCS 60
MWAAGRWGPTFPSSYAGFSADCRPRSRPSSDSCSVPMTGARGQGLEVVRSPSPPLPLSCS
Sbjct: 1 MWAAGRWGPTFPSSYAGFSADCRPRSRPSSDSCSVPMTGARGQGLEVVRSPSPPLPLSCS 60
Query: 61 NSTRSLLSPLGHQSFQFDEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCAS 120
NSTRSLLSPLGHQSFQFDEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCAS
Sbjct: 61 NSTRSLLSPLGHQSFQFDEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCAS 120
Query: 121 TQVESENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEE 180
TQVESENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEE
Sbjct: 121 TQVESENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEE 180
Query: 181 REKRKIIAEEKHKEWVQKKNEQKRK 205
REKRKIIAEEKHKEWVQKKNEQ R+
Sbjct: 181 REKRKIIAEEKHKEWVQKKNEQVRR 205
Score = 33.5 bits (75), Expect = 0.32
Identities = 25/96 (26%), Positives = 47/96 (48%), Gaps = 11/96 (11%)
Query: 214 EMEEKAAKELEKEYLQEKAKE---------KYQEWLKKKNAEECERKKKEKEKEKQQQAE 264
E++ A+ ++E E QE+ K+ ++ W K EE +R + + +E QQ E
Sbjct: 114 ELQGCASTQVESENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLE 173
Query: 265 IQEKKEIAEKKFQEWLENAKHKPRPAAKSYGYANGK 300
++KE+ E++ ++ + KHK K+ GK
Sbjct: 174 --KRKEMEEREKRKIIAEEKHKEWVQKKNEQVRRGK 207
>gi|88759339 aster-associated protein [Homo sapiens]
Length = 647
Score = 88.2 bits (217), Expect = 1e-17
Identities = 71/211 (33%), Positives = 104/211 (49%), Gaps = 30/211 (14%)
Query: 122 QVESENN--QEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEME 179
++ESEN Q EQK+ E L +E W KEKE + K LEE N K+K E
Sbjct: 448 RIESENLRIQNEQKKAAKREEALASFEAWKAMKEKEAKKIAAKKRLEEKN----KKKTEE 503
Query: 180 EREKRKIIAEEKHKEWVQKK----NEQKRKERE-QKINKEMEEKAAKELEKEYLQ--EKA 232
E RK A + ++W +KK E+ RKERE ++ K+ EE+ E +K+ L EK
Sbjct: 504 ENAARKGEALQAFEKWKEKKMEYLKEKNRKEREYERAKKQKEEETVAEKKKDNLTAVEKW 563
Query: 233 KEKYQEWLKKKNAEECERKKKEKEKEKQQQAEIQEKKEIAEKKFQEWLENAKHKPRPAAK 292
EK + + K+K E K EK KE+ ++AE ++K + A ++++WLEN + + R K
Sbjct: 564 NEKKEAFFKQKEKE----KINEKRKEELKRAEKKDKDKQAINEYEKWLENKEKQERIERK 619
Query: 293 SYGYANGKLTGFYSGNSYPEPAFYNPIPWKP 323
K F + P PW P
Sbjct: 620 -----QKKRHSFLESEALP--------PWSP 637
Score = 47.8 bits (112), Expect = 2e-05
Identities = 60/258 (23%), Positives = 105/258 (40%), Gaps = 60/258 (23%)
Query: 78 DEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRL 137
D ++ + E +DD+ VD S++ + S +N + +
Sbjct: 311 DLEEEKAKAELIMDDDRTVDPLLSKSQSILISTSATASSKKTIEDRNIKNKKSTNNRASS 370
Query: 138 PESRLTPWEVWFIGKEKEER-------DRLQLKALEELNQQLEKRKEMEEREKRKIIAEE 190
+RL E F+ K +R L L+ L+Q+ +++ +E ++ I
Sbjct: 371 ASARLMTSE--FLKKSSSKRRTPSTTTSSHYLGTLKVLDQKPSQKQSIEP-DRADNIRAA 427
Query: 191 KHKEWVQKK---------------------NEQKR-----------------KEREQK-- 210
++EW++KK NEQK+ KE+E K
Sbjct: 428 VYQEWLEKKNVYLHEMHRIKRIESENLRIQNEQKKAAKREEALASFEAWKAMKEKEAKKI 487
Query: 211 -INKEMEEKAAKELEKEYLQ---------EKAKEKYQEWLKKKNAEECERKKKEKEKEKQ 260
K +EEK K+ E+E EK KEK E+LK+KN +E E ++ +K+KE++
Sbjct: 488 AAKKRLEEKNKKKTEEENAARKGEALQAFEKWKEKKMEYLKEKNRKEREYERAKKQKEEE 547
Query: 261 QQAEIQEKKEIAEKKFQE 278
AE ++ A +K+ E
Sbjct: 548 TVAEKKKDNLTAVEKWNE 565
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 75.5 bits (184), Expect = 7e-14
Identities = 54/175 (30%), Positives = 96/175 (54%), Gaps = 11/175 (6%)
Query: 122 QVESENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEER 181
Q E + QE+Q++ R E R W + +E++ R R L A L +QL K +++ +
Sbjct: 850 QEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRR-RHTLYAKPALQEQLRKEQQLLQE 908
Query: 182 EKRKIIAEEKHKEWVQ------KKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEK 235
E+ ++ EE+ K Q ++ EQ ++E EQ + +E E++ +E E++Y ++K ++
Sbjct: 909 EEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQ 968
Query: 236 YQEWLKKKNAEE---CERKKKEKEKEKQQQAEIQEKKEIAEK-KFQEWLENAKHK 286
+E L + E+ ER+KK +E+E+ QQ E Q +E EK + QEW + K
Sbjct: 969 KEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKK 1023
Score = 68.9 bits (167), Expect = 7e-12
Identities = 55/228 (24%), Positives = 118/228 (51%), Gaps = 29/228 (12%)
Query: 66 LLSPLGHQSFQFDEDDG-----------DGEDEEDVDDEEDVDEDAHDSEAKVASLRGME 114
L S GH++ +F +++ G +E+ E D + E K R
Sbjct: 193 LQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETV 252
Query: 115 LQGCASTQVESENNQEE----QKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQ 170
L+ E E QEE Q++++ E +L E + +E++E ++ Q + E Q
Sbjct: 253 LRK------EEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRRE--Q 304
Query: 171 QLEKRKEMEEREKRKIIAEEKHKEWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQE 230
QL +++E E RE++ EE+ ++ Q++ EQ+ + REQ++ +E EE+ ++L +E +E
Sbjct: 305 QLRRKQEEERREQQ----EERREQ--QERREQQEERREQQLRREQEERREQQLRREQEEE 358
Query: 231 KAKEKYQEWLKKKNAEECERKKKEKEKEKQQQAEIQEKKEIAEKKFQE 278
+ +++ + +++ E+ R++++ +E+Q + E Q ++E ++ Q+
Sbjct: 359 RREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 406
Score = 68.9 bits (167), Expect = 7e-12
Identities = 51/164 (31%), Positives = 93/164 (56%), Gaps = 17/164 (10%)
Query: 124 ESENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKAL----EELNQQLEK--RKE 177
E QE ++Q R E L E +G+E+E R R +L+ EEL Q+ E+ R+E
Sbjct: 1039 EKRRLQERERQYR-EEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREE 1097
Query: 178 MEEREKRKIIAEEKHKEWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQ 237
E+R +++ +E ++ E+ ++E EQ + +E E++ +ELE++Y +E+ ++ +
Sbjct: 1098 PEKRRRQE-------RERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEE 1150
Query: 238 EWLKKKNAEECERKKKE---KEKEKQQQAEIQEKKEIAEKKFQE 278
E L ++ E+ R++ E +E+E+ QQ E Q +E EK+ QE
Sbjct: 1151 EQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQE 1194
Score = 68.6 bits (166), Expect = 9e-12
Identities = 58/231 (25%), Positives = 118/231 (51%), Gaps = 36/231 (15%)
Query: 91 DDEEDVDEDAHDSEAKVASLRGM--ELQGCASTQVESENNQEEQKQVRLPESRLTPWEVW 148
+ EE+ E H+ E + L+ E + + E+E +++E+++ +L +
Sbjct: 428 EQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRER 487
Query: 149 FIGKEKEERDRLQLKALEELNQQLE-------KRKEMEEREKRKIIAE-------EKHKE 194
++ E+EER Q + ++L ++ E KR+E EER ++++ +E E+ +E
Sbjct: 488 WLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERRE 547
Query: 195 WVQKKNEQKRKE---REQKINKEMEE------KAAKELEKEYLQEKAKEKYQEWLKKKNA 245
+ K+ E+KR E REQ++ +E EE K +E ++ L+ + +E+ ++ LK++
Sbjct: 548 QLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEV 607
Query: 246 EECER--------KKKEKEKEKQQQAEIQEKKEIAEKKFQEWLENAKHKPR 288
E E+ K++E E+E++QQ K E E++ Q+ L + + R
Sbjct: 608 ERLEQEERREQRLKREEPEEERRQQL---LKSEEQEERRQQQLRREQQERR 655
Score = 68.2 bits (165), Expect = 1e-11
Identities = 55/195 (28%), Positives = 109/195 (55%), Gaps = 28/195 (14%)
Query: 76 QFDEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQV 135
+ E + +EE++ EE E E + + +E Q + E E QEE++ +
Sbjct: 1042 RLQERERQYREEEELQQEE---EQLLGEERETRRRQELERQ----YRKEEELQQEEEQLL 1094
Query: 136 RL-PESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKE 194
R PE R ++ER+R Q + EEL Q+ E++ EEREKR+ +E ++
Sbjct: 1095 REEPEKR-----------RRQERER-QCREEEELQQE-EEQLLREEREKRR--RQELERQ 1139
Query: 195 WVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEECERKKKE 254
+ ++ E+ ++E EQ + +E E++ +ELE++Y +E+ ++ +E L + EE E++++E
Sbjct: 1140 Y--REEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLR---EEQEKRRQE 1194
Query: 255 KEKEKQQQAEIQEKK 269
+E++ +++ E+Q +K
Sbjct: 1195 RERQYREEEELQRQK 1209
Score = 67.8 bits (164), Expect = 2e-11
Identities = 56/221 (25%), Positives = 116/221 (52%), Gaps = 21/221 (9%)
Query: 73 QSFQFDEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMEL--QGCASTQVESENNQE 130
Q Q+ E++ ++EE + EE + E + + ++ + + E QE
Sbjct: 926 QERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQE 985
Query: 131 EQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEE 190
+K+ R E L E + +E+E+R R +E +Q K+ E+++ E++ ++ EE
Sbjct: 986 REKKYR-EEEELQQEEEQLLREEREKRRR------QEWERQYRKKDELQQEEEQ-LLREE 1037
Query: 191 KHKEWVQKKNEQKRK-------EREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKK 243
+ K +Q++ E++ + E EQ + +E E + +ELE++Y +E+ ++ +E L ++
Sbjct: 1038 REKRRLQER-ERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLRE 1096
Query: 244 NAEECERKKKE---KEKEKQQQAEIQEKKEIAEKKFQEWLE 281
E+ R+++E +E+E+ QQ E Q +E EK+ ++ LE
Sbjct: 1097 EPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELE 1137
Score = 67.0 bits (162), Expect = 3e-11
Identities = 53/206 (25%), Positives = 107/206 (51%), Gaps = 20/206 (9%)
Query: 85 EDEEDVDDEEDVDEDAHDSEAKVASLRGM--ELQGCASTQVESENNQEEQKQVRLPESRL 142
E+EE++ EE + E + + E + + E QE ++Q R + +L
Sbjct: 908 EEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYR-KDKKL 966
Query: 143 TPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEM---EEREKRKIIAEEKHKEWVQ-- 197
E +G+E E+R R + + ++L++ +E EEREKR+ +EW +
Sbjct: 967 QQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRR------RQEWERQY 1020
Query: 198 KKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWL-----KKKNAEECERKK 252
+K ++ ++E EQ + +E E++ +E E++Y +E+ ++ +E L + + +E ER+
Sbjct: 1021 RKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQY 1080
Query: 253 KEKEKEKQQQAEIQEKKEIAEKKFQE 278
+ KE+E QQ+ E ++E +++ QE
Sbjct: 1081 R-KEEELQQEEEQLLREEPEKRRRQE 1105
Score = 64.7 bits (156), Expect = 1e-10
Identities = 47/172 (27%), Positives = 90/172 (52%), Gaps = 16/172 (9%)
Query: 129 QEEQKQVRLP-------ESRLTPWEVWFIGKEKEERDRLQLKALEE-LNQQLEKRKEMEE 180
+EE++Q RL E RL EV + +E+ RL+ + EE QQL K +E EE
Sbjct: 582 EEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEE 641
Query: 181 REKRKIIAEEKHKEWVQKKNEQKRKEREQKINKEMEEKAAK----ELEKEYLQEKAKEKY 236
R ++++ E++ + + K E++ + EQ++ +E EE+ + E E+E +E+ K +
Sbjct: 642 RRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRI 701
Query: 237 QEWLKKKNAEECERKKK----EKEKEKQQQAEIQEKKEIAEKKFQEWLENAK 284
+W + +E R+ K +++E Q++ + QE+K + +W E +
Sbjct: 702 PKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEER 753
Score = 63.9 bits (154), Expect = 2e-10
Identities = 52/223 (23%), Positives = 115/223 (51%), Gaps = 31/223 (13%)
Query: 85 EDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPESRLTP 144
E+E+ ++E + + E ++ L EL+ E +EEQ+Q RL +
Sbjct: 256 EEEKLQEEEPQRQRELQEEEEQLRKLERQELR--------RERQEEEQQQQRLRREQQLR 307
Query: 145 WEVWFIGKEKEERDRLQLKALEELNQQLEK--RKEMEEREKRKIIAE---EKHKEWVQKK 199
+ +E++E R Q + E+ ++ E+ R+E EER ++++ E E+ ++ ++++
Sbjct: 308 RKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRRE 367
Query: 200 NEQKRKE----------REQKINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEECE 249
E++R+E REQ++ +E + + ++L +E Q+ +E Q+ +++ +
Sbjct: 368 QEEERREQQLRREQQLRREQQLRREQQLRREQQLRRE--QQLRRE--QQLRREQQLRREQ 423
Query: 250 RKKKEKEKEKQQQAEIQEKKEIAEKKFQE----WLENAKHKPR 288
+ ++E+E+E+ +Q QE++E K+ QE WL+ + R
Sbjct: 424 QLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETER 466
Score = 62.8 bits (151), Expect = 5e-10
Identities = 48/213 (22%), Positives = 107/213 (50%), Gaps = 15/213 (7%)
Query: 76 QFDEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQV 135
Q +E E E ++ + E + LR + + Q+ E +E ++Q
Sbjct: 317 QQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQ 376
Query: 136 RLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEW 195
E +L + + +E++ R QL+ ++L ++ + R+E + R ++++ E++ +
Sbjct: 377 LRREQQLRREQQ--LRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERH 434
Query: 196 VQKKNEQKRKEREQKINKEMEEKAAKELEKE-YLQEKAK---------EKYQEWLKKKNA 245
QK +++R++R ++ +E + +E E E + QE+ K E+ + WLK
Sbjct: 435 EQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLK---L 491
Query: 246 EECERKKKEKEKEKQQQAEIQEKKEIAEKKFQE 278
EE ER+++++ +E+Q + E +E++E K+ +E
Sbjct: 492 EEEERREQQERREQQLRREQEERREQRLKRQEE 524
Score = 62.8 bits (151), Expect = 5e-10
Identities = 47/160 (29%), Positives = 93/160 (58%), Gaps = 19/160 (11%)
Query: 126 ENNQEEQKQVRLPESRLTPWEVWFIGKEKEER--DRLQLKALEELNQQLEK----RKEME 179
E + EQ+ R E R + K +EER RL+ + E L Q+L++ R E E
Sbjct: 559 EQERREQRLKREQEERRDQ-----LLKREEERRQQRLKREQEERLEQRLKREEVERLEQE 613
Query: 180 EREKRKIIAEEKHKEWVQK--KNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQ 237
ER ++++ EE +E Q+ K+E++ + R+Q++ +E +E+ + L++ E+ +E+ +
Sbjct: 614 ERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKR----EEEEERLE 669
Query: 238 EWLKKKNAEECERKKKEKEKEKQQQAEIQEKKEIAEKKFQ 277
+ LK+++ E ER+++E +E+Q+QA + K I + ++Q
Sbjct: 670 QRLKREHEE--ERREQELAEEEQEQARERIKSRIPKWQWQ 707
Score = 62.0 bits (149), Expect = 8e-10
Identities = 54/230 (23%), Positives = 113/230 (49%), Gaps = 16/230 (6%)
Query: 79 EDDGDGEDEEDVDDEEDVDEDAHDS----EAKVASLRGMELQGCASTQVESENNQEEQKQ 134
E + ++EE ++ +E D +A+ S RG + E Q ++
Sbjct: 743 ESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEE 802
Query: 135 VRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKE 194
+ E R P E +EKE+R R + + +EL Q LE+ ++++ RE+ + + EE+ +
Sbjct: 803 RQQREQRFLPEE-----EEKEQRRRQRREREKEL-QFLEEEEQLQRRERAQQLQEEE--D 854
Query: 195 WVQKKNEQKRKE---REQKINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEECERK 251
+Q+ E++R + R+QK ++EE+ + Y + +E+ ++ + EE E +
Sbjct: 855 GLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQ 914
Query: 252 KKEKEKEKQQQAEIQ-EKKEIAEKKFQEWLENAKHKPRPAAKSYGYANGK 300
++E+EK ++Q+ E Q ++E +++ ++ L + K R + Y K
Sbjct: 915 REEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDK 964
Score = 60.8 bits (146), Expect = 2e-09
Identities = 50/215 (23%), Positives = 111/215 (51%), Gaps = 16/215 (7%)
Query: 85 EDEEDVDDEEDVDE-DAHDSEA--KVASLRGMELQGCASTQVESENNQEEQKQVRLPESR 141
E EE +EE + H++E LR EL ++ + +E+Q+Q R + R
Sbjct: 182 EREERRAEEEQLQSCKGHETEEFPDEEQLRRREL-----LELRRKGREEKQQQRRERQDR 236
Query: 142 LTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQKKNE 201
+ E +++E R + + L+E Q ++ + EE + RK+ +E +E +++ +
Sbjct: 237 VFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQ 296
Query: 202 QKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQE----WLKKKNAEECE----RKKK 253
Q+R REQ++ ++ EE+ ++ E+ Q++ +E+ +E L+++ E E R+++
Sbjct: 297 QQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQE 356
Query: 254 EKEKEKQQQAEIQEKKEIAEKKFQEWLENAKHKPR 288
E+ +E+Q + E +E++ + + ++ L + R
Sbjct: 357 EERREQQLRREQEEERREQQLRREQQLRREQQLRR 391
Score = 60.8 bits (146), Expect = 2e-09
Identities = 46/205 (22%), Positives = 109/205 (53%), Gaps = 22/205 (10%)
Query: 85 EDEEDVDDEE---DVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPESR 141
E EE+ +++ + +E+ + + + E Q Q+ E ++Q+R +
Sbjct: 354 EQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ- 412
Query: 142 LTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQKKNE 201
+ +E++ R QL+ +E ++ E++ E E RE+R +E+ ++W++++ E
Sbjct: 413 --------LRREQQLRREQQLRREQE-EERHEQKHEQERREQRLKREQEERRDWLKREEE 463
Query: 202 QKRKE---REQKINKEMEEKAAK---ELEKEYLQEKAKEKYQEWLKKKNAEECERKKKEK 255
+R E R+Q++ ++ EE+ + +LE+E +E+ + + Q+ +++ +R K+++
Sbjct: 464 TERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQE 523
Query: 256 EKEKQQQ---AEIQEKKEIAEKKFQ 277
E+E+ QQ +E Q ++E E++ Q
Sbjct: 524 EEERLQQRLRSEQQLRREQEERREQ 548
Score = 60.8 bits (146), Expect = 2e-09
Identities = 55/220 (25%), Positives = 110/220 (50%), Gaps = 23/220 (10%)
Query: 85 EDEEDVDDEEDVDEDAH--DSEAKVASLRGMELQGCASTQVESENN----QEEQKQVRLP 138
E+EE + +E ++ E + L+ E + ++ SE QEE+++ L
Sbjct: 492 EEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLK 551
Query: 139 ---ESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEW 195
E RL E+E R++ + EE QL KR+E E R++R +E+ E
Sbjct: 552 REEEKRL----------EQERREQRLKREQEERRDQLLKREE-ERRQQRLKREQEERLEQ 600
Query: 196 VQKKNEQKRKEREQKINKEMEEKAAKELEKEYL--QEKAKEKYQEWLKKKNAEECERKKK 253
K+ E +R E+E++ + ++ + +E ++ L E+ +E+ Q+ L+++ E E++ K
Sbjct: 601 RLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLK 660
Query: 254 EKEKEKQQQAEIQEKKEIAEKKFQEWLENAKHKPRPAAKS 293
+E+E++ + ++ + E E++ QE E + + R KS
Sbjct: 661 REEEEERLEQRLKREHE-EERREQELAEEEQEQARERIKS 699
Score = 60.5 bits (145), Expect = 2e-09
Identities = 42/177 (23%), Positives = 95/177 (53%), Gaps = 15/177 (8%)
Query: 122 QVESENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEER 181
Q+ E +E +Q E R E +++E RD L+ + E ++Q E+RK+ +R
Sbjct: 424 QLRREQEEERHEQKHEQERR----EQRLKREQEERRDWLKREEETERHEQ-ERRKQQLKR 478
Query: 182 EKRKIIAEEKHKEWVQKKNEQKRKE---REQKINKEMEEKAAKELEKEYLQEKAKEKYQE 238
++ EE+ + W++ + E++R++ REQ++ +E EE+ + L+++ +E+ +++ +
Sbjct: 479 DQE----EERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRS 534
Query: 239 WLKKKNAEECERK---KKEKEKEKQQQAEIQEKKEIAEKKFQEWLENAKHKPRPAAK 292
+ + +E R+ K+E+EK +Q+ Q K E++ + L+ + + + K
Sbjct: 535 EQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLK 591
Score = 58.2 bits (139), Expect = 1e-08
Identities = 39/157 (24%), Positives = 93/157 (59%), Gaps = 7/157 (4%)
Query: 127 NNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKR-----KEMEER 181
+ QE ++ RL E ++ E E E++ R Q + ++L Q+ +++ + ++ER
Sbjct: 1573 SRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQ-EGQQQLRQERDRKFREDEQLLQER 1631
Query: 182 EKRKIIAEEKHKEWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWLK 241
E++++ +E+ +++++++ + +R+EREQ++ + + K +E + E+ + + QE +
Sbjct: 1632 EEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDR 1691
Query: 242 KKNAEECERKKKEKEKEKQQQAEIQEKKEIAEKKFQE 278
K EE + +++E+E+ K Q E Q +++ E+KF+E
Sbjct: 1692 KFREEEQQLRRQERER-KFLQEEQQLRRQELERKFRE 1727
Score = 58.2 bits (139), Expect = 1e-08
Identities = 50/219 (22%), Positives = 107/219 (48%), Gaps = 39/219 (17%)
Query: 71 GHQSFQFDEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQE 130
G Q + + D EDE+ + + E+ + + K + QE
Sbjct: 1609 GQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLE------------EEPQLRRQE 1656
Query: 131 EQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEE 190
++Q+R R K +EE LQ ++L +Q RK EE ++ + +E
Sbjct: 1657 REQQLRHDRDR----------KFREEEQLLQEGEEQQLRRQERDRKFREEEQQLR--RQE 1704
Query: 191 KHKEWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKK------- 243
+ ++++Q++ + +R+E E+K + EE+ +E E+E L + +E+Y++ L+++
Sbjct: 1705 RERKFLQEEQQLRRQELERKFRE--EEQLRQETEQEQL--RRQERYRKILEEEQLRPERE 1760
Query: 244 ----NAEECERKKKEKEKEKQQQAEIQEKKEIAEKKFQE 278
+E +RK +E+E+ +Q++ E Q + + +++KF+E
Sbjct: 1761 EQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFRE 1799
Score = 57.8 bits (138), Expect = 2e-08
Identities = 45/215 (20%), Positives = 104/215 (48%), Gaps = 17/215 (7%)
Query: 85 EDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPESRLTP 144
+D +D+ + E + R + Q E E E+Q+++ + +
Sbjct: 111 QDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRD 170
Query: 145 WEVWFIGKEKEERD--RLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQKKNEQ 202
E+W +E +ER+ R + + L+ + EE+ +R+ + E + K +++ +Q
Sbjct: 171 EELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKG--REEKQQ 228
Query: 203 KRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAE-----------ECERK 251
+R+ER+ ++ +E EEK ++ +E + K +EK QE ++ E E +
Sbjct: 229 QRRERQDRVFQEEEEKEWRK--RETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQEL 286
Query: 252 KKEKEKEKQQQAEIQEKKEIAEKKFQEWLENAKHK 286
++E+++E+QQQ ++ ++++ K+ +E E + +
Sbjct: 287 RRERQEEEQQQQRLRREQQLRRKQEEERREQQEER 321
Score = 57.8 bits (138), Expect = 2e-08
Identities = 42/180 (23%), Positives = 96/180 (53%), Gaps = 30/180 (16%)
Query: 129 QEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEE----LNQQLEKRKEMEEREKR 184
+EE+K+ R + R E+ F+ +E++ + R + + L+E L + E+R+ E+R +
Sbjct: 813 EEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQ 872
Query: 185 K---------------IIAEEKHKEWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQ 229
K + A+ +E ++K+ + ++E E+ +E E++ +E E++Y +
Sbjct: 873 KWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYRE 932
Query: 230 EKAKEKYQEWLKKKNAEECERKKKE----KEKEKQQQAE-------IQEKKEIAEKKFQE 278
E+ ++ +E L ++ E+ R+++E K+K+ QQ+ E + +++ EKK++E
Sbjct: 933 EEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYRE 992
Score = 57.4 bits (137), Expect = 2e-08
Identities = 38/158 (24%), Positives = 92/158 (58%), Gaps = 6/158 (3%)
Query: 124 ESENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQ---LKALEELNQQLEKRKEMEE 180
E + Q+ ++ R E +L+ E +E+E++ R Q K LEE QQL + + +
Sbjct: 1405 EQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEE-EQQLRQERHRKF 1463
Query: 181 REKRKIIAEEKHKEWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWL 240
RE+ +++ E + ++ +++ ++K E EQ++ + +E+ K E+E ++ + K+ E
Sbjct: 1464 REEEQLLQEREEQQLHRQERDRKFLEEEQQLRR--QERDRKFREQELRSQEPERKFLEEE 1521
Query: 241 KKKNAEECERKKKEKEKEKQQQAEIQEKKEIAEKKFQE 278
++ + ++ +RK ++E++ ++Q Q++++ ++KF+E
Sbjct: 1522 QQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFRE 1559
Score = 57.0 bits (136), Expect = 3e-08
Identities = 33/127 (25%), Positives = 78/127 (61%), Gaps = 3/127 (2%)
Query: 154 KEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQKKNEQKRKEREQKINK 213
++ER+ QL++ E + E+ + +ERE++++ +++ ++ ++ + + +E+EQ++ +
Sbjct: 1780 RQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQ 1839
Query: 214 EMEEKAAKELEKEYLQEKAKEKYQE-WLKKKNAEECERKKKEKEKE-KQQQAEIQEKKEI 271
E + + E E+ QEK++ + QE W +++ ER++K +E+ ++QQ E Q +++
Sbjct: 1840 ERDRQYRAE-EQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQV 1898
Query: 272 AEKKFQE 278
E K QE
Sbjct: 1899 GEIKSQE 1905
Score = 55.1 bits (131), Expect = 1e-07
Identities = 49/231 (21%), Positives = 111/231 (48%), Gaps = 38/231 (16%)
Query: 76 QFDEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQV 135
++ + D +EE ++ EE + D +++ E Q + E QE ++
Sbjct: 1285 RWQQRDRHFPEEEQLEREEQKEAKRRDRKSQE------EKQLLREEREEKRRRQETDRKF 1338
Query: 136 RLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREK-------RKIIA 188
R E L E + ++ERDR + EEL Q + RK +EE ++ RK +
Sbjct: 1339 REEEQLLQEREEQPL--RRQERDRKFRE--EELRHQEQGRKFLEEEQRLRRQERERKFLK 1394
Query: 189 EEKH---------------KEWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAK 233
EE+ +++ +++ + R+ER++K +E ++ +E E+++L+E+ +
Sbjct: 1395 EEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQ 1454
Query: 234 EKYQEWLKKKNAEECERKKKEKEKEKQQ------QAEIQEKKEIAEKKFQE 278
+ + K + E+ ++++E++ +Q+ + E Q +++ ++KF+E
Sbjct: 1455 LRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFRE 1505
Score = 55.1 bits (131), Expect = 1e-07
Identities = 30/129 (23%), Positives = 79/129 (61%), Gaps = 5/129 (3%)
Query: 154 KEERDRL----QLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQKKNEQKRKEREQ 209
++ERDR +L++ E + LE+ +++ +++++ +E+ + Q++ +Q+R++R++
Sbjct: 1496 RQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDR 1555
Query: 210 KINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEECERKKKEKEKEKQQQAEIQEKK 269
K +E + + +E E++ +++ K++ +K +E ERK E E++ ++Q Q+ +
Sbjct: 1556 KFREEEQLRQERE-EQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLR 1614
Query: 270 EIAEKKFQE 278
+ ++KF+E
Sbjct: 1615 QERDRKFRE 1623
Score = 54.7 bits (130), Expect = 1e-07
Identities = 46/182 (25%), Positives = 94/182 (51%), Gaps = 18/182 (9%)
Query: 122 QVESENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQL-KALEELNQQLEKRKE--- 177
++E E +E++ + PE + +E+EER + QL + +E +Q KR+E
Sbjct: 609 RLEQEERREQRLKREEPEEERR--QQLLKSEEQEERRQQQLRREQQERREQRLKREEEEE 666
Query: 178 -MEEREKRKIIAEEKHKEWVQKKNEQKRKEREQKINK---EMEEKAAKELEKEYLQEKAK 233
+E+R KR+ E + +E +++ EQ R+ + +I K ++E +A K Y + + +
Sbjct: 667 RLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQ 726
Query: 234 E---KYQEWLKKKNAEECERKKKEKEKEKQQQAEIQEKKEI-----AEKKFQEWLENAKH 285
E + QE +K+ E E + +E+E+ +QQ E +++++ AE+K + +
Sbjct: 727 EGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSA 786
Query: 286 KP 287
+P
Sbjct: 787 RP 788
Score = 54.3 bits (129), Expect = 2e-07
Identities = 40/173 (23%), Positives = 88/173 (50%), Gaps = 20/173 (11%)
Query: 126 ENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLK--------------ALEELNQQ 171
EN Q Q + R + ++ + E++ERDR Q + LE Q+
Sbjct: 1246 ENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQK 1305
Query: 172 LEKRKEMEEREKRKIIAEEKHKEWVQKKNEQKRKEREQKINKEME------EKAAKELEK 225
KR++ + +E+++++ EE+ ++ +++ ++K +E EQ + + E E+ K E+
Sbjct: 1306 EAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREE 1365
Query: 226 EYLQEKAKEKYQEWLKKKNAEECERKKKEKEKEKQQQAEIQEKKEIAEKKFQE 278
E ++ K+ E ++ +E ERK ++E++ + Q Q+ ++ ++KF+E
Sbjct: 1366 ELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFRE 1418
Score = 54.3 bits (129), Expect = 2e-07
Identities = 40/163 (24%), Positives = 91/163 (55%), Gaps = 14/163 (8%)
Query: 120 STQVESENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEME 179
S Q +EE++QVR E E F+ +E++ R K EE Q L++R+E +
Sbjct: 1424 SRQERDRKFREEEQQVRRQER-----ERKFLEEEQQLRQERHRKFREE-EQLLQEREEQQ 1477
Query: 180 ---EREKRKIIAEEKHKEWVQKKNEQKRKEREQKI-NKEMEEKAAKELEKEYLQEKAKEK 235
+ RK + EE+ ++ E+ RK REQ++ ++E E K +E ++ + Q++ ++
Sbjct: 1478 LHRQERDRKFLEEEQQ----LRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKF 1533
Query: 236 YQEWLKKKNAEECERKKKEKEKEKQQQAEIQEKKEIAEKKFQE 278
QE + + E ++++++++++ +++ ++++++E + QE
Sbjct: 1534 LQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQE 1576
Score = 53.1 bits (126), Expect = 4e-07
Identities = 49/223 (21%), Positives = 110/223 (49%), Gaps = 18/223 (8%)
Query: 76 QFDEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGM--ELQGCASTQVESENNQEEQK 133
Q+ E++ ++EE + EE + E + + E + + E QE ++
Sbjct: 1049 QYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERER 1108
Query: 134 QVRLPESRLTPWEVWFIGKEKEERDRLQLKAL----EELNQQLEK--RKEMEEREKRKII 187
Q R E L E + +E+E+R R +L+ EE+ Q+ E+ R+E E+R ++++
Sbjct: 1109 QCR-EEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELE 1167
Query: 188 AEEKHKEWVQKKNEQ--------KRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEW 239
+ + +E +Q++ EQ +R+ERE++ +E E + K ++ +++ + +W
Sbjct: 1168 RQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQW 1227
Query: 240 LKKKNAEECERKKKEKEKEKQQQAEIQEKKEIAEKKFQEWLEN 282
+K + K K +E +Q ++ E ++ +++ Q+ L++
Sbjct: 1228 EPEKENAVRDNKVYCKGRENEQFRQL-EDSQLRDRQSQQDLQH 1269
Score = 53.1 bits (126), Expect = 4e-07
Identities = 36/148 (24%), Positives = 87/148 (58%), Gaps = 15/148 (10%)
Query: 130 EEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAE 189
EE++Q+R R K +EE LQ + ++L++Q RK +EE ++ + +
Sbjct: 1450 EEEQQLRQERHR----------KFREEEQLLQEREEQQLHRQERDRKFLEEEQQLR--RQ 1497
Query: 190 EKHKEWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEECE 249
E+ +++ ++ E + +E E+K +E ++ ++ ++++LQE+ + + QE ++ ++ +
Sbjct: 1498 ERDRKF--REQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQE-RGQQRRQDRD 1554
Query: 250 RKKKEKEKEKQQQAEIQEKKEIAEKKFQ 277
RK +E+E+ +Q++ E Q ++ ++KF+
Sbjct: 1555 RKFREEEQLRQEREEQQLSRQERDRKFR 1582
Score = 52.8 bits (125), Expect = 5e-07
Identities = 46/226 (20%), Positives = 118/226 (52%), Gaps = 27/226 (11%)
Query: 86 DEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPESRLTPW 145
D + +++E+ + D + + LR E + + + + Q+ Q++ E +L
Sbjct: 1484 DRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQ 1543
Query: 146 EVWFIGKEKEERDRLQLKALEELNQQLEK----RKEMEER---EKRKIIAEEKHKEWV-- 196
E + +++RDR + + E+L Q+ E+ R+E + + E++K+ +E+ ++++
Sbjct: 1544 ERG--QQRRQDRDR-KFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMED 1600
Query: 197 ------QKKNEQKRKEREQKI--------NKEMEEKAAKELEKEYLQEKAKEKYQEWLKK 242
Q+ +Q R+ER++K +E ++ +E ++++L+E+ + + QE ++
Sbjct: 1601 EQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQE-REQ 1659
Query: 243 KNAEECERKKKEKEKEKQQQAEIQEKKEIAEKKFQEWLENAKHKPR 288
+ + +RK +E+E+ Q+ E Q +++ ++KF+E + + + R
Sbjct: 1660 QLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQER 1705
Score = 52.4 bits (124), Expect = 7e-07
Identities = 40/171 (23%), Positives = 87/171 (50%), Gaps = 13/171 (7%)
Query: 124 ESENNQEEQKQVR-LPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEERE 182
E E +EEQ+Q R +SR+ W+ W + + E D Q K +Q +R+ E+ E
Sbjct: 682 EQELAEEEQEQARERIKSRIPKWQ-WQL---ESEADARQSKVYSRPRKQEGQRRRQEQEE 737
Query: 183 KRKIIAEEKHKEWVQKKNEQKRKEREQKINK-----EMEEKAAKELEKEYLQEKAKEKYQ 237
KR+ E +W +++ ++++ E++ + EEK+ + ++ + +E+ +
Sbjct: 738 KRR--RRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRE 795
Query: 238 EWLKKKNAEECERKKKEKEKEKQQQAEIQEKKEIAEKKFQEWLENAKHKPR 288
L+ + ++ E++ +E+EK+Q+ + ++E E +F E E + + R
Sbjct: 796 RQLRAEERQQREQRFLPEEEEKEQRRRQRRERE-KELQFLEEEEQLQRRER 845
Score = 52.4 bits (124), Expect = 7e-07
Identities = 44/178 (24%), Positives = 94/178 (52%), Gaps = 20/178 (11%)
Query: 124 ESENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREK 183
+ E ++E++++ R P E +E++E R K+ EE E+R+E R++
Sbjct: 1274 QQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQE 1333
Query: 184 --RKIIAEEK----HKEWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQ 237
RK EE+ +E ++ E+ RK RE+++ +E+ K LE+E + + +E+ +
Sbjct: 1334 TDRKFREEEQLLQEREEQPLRRQERDRKFREEELRH--QEQGRKFLEEEQ-RLRRQERER 1390
Query: 238 EWLKKKNAEECERKKKE-------KEKEKQQQAEIQEKKEIAEKKFQEWLENAKHKPR 288
++LK++ C+ ++++ K +E++QQ QE+ ++KF+E + + + R
Sbjct: 1391 KFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQER----DRKFREEEQQVRRQER 1444
Score = 52.0 bits (123), Expect = 9e-07
Identities = 46/210 (21%), Positives = 105/210 (50%), Gaps = 15/210 (7%)
Query: 92 DEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPESRLTPWEVWFIG 151
D + +E+ E + LR E + + QE +++ E +L E+
Sbjct: 1666 DRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKF 1725
Query: 152 KEKE----ERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQKKNEQKRKER 207
+E+E E ++ QL+ E + LE+ + ERE++++ +E+ +++ ++ EQ R+ER
Sbjct: 1726 REEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKF--REEEQLRQER 1783
Query: 208 EQKINKEME--------EKAAKELEKEYLQEKAKEKYQEWLKKKNAEECERKKKEKEKEK 259
E++ + E E+ +E E++ L+ + ++ W +++ E + ++ +E+++
Sbjct: 1784 EEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDR 1843
Query: 260 QQQAEIQ-EKKEIAEKKFQEWLENAKHKPR 288
Q +AE Q +E + ++ QE + + K R
Sbjct: 1844 QYRAEEQFATQEKSRREEQELWQEEEQKRR 1873
Score = 51.2 bits (121), Expect = 1e-06
Identities = 35/144 (24%), Positives = 82/144 (56%), Gaps = 15/144 (10%)
Query: 146 EVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQKKN---EQ 202
+V+ G+E E+ +L+ L + Q + + + E+++R E++ + W Q+ E+
Sbjct: 1239 KVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERD--REQERRRWQQRDRHFPEE 1296
Query: 203 KRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEECERKKKEKEKEKQQQ 262
++ ERE++ + ++ ++E EK+ L+E+ +EK + +E +RK +E+E+ Q++
Sbjct: 1297 EQLEREEQKEAKRRDRKSQE-EKQLLREEREEK-------RRRQETDRKFREEEQLLQER 1348
Query: 263 AEIQEKKEIAEKKFQEWLENAKHK 286
E +++ ++KF+E E +H+
Sbjct: 1349 EEQPLRRQERDRKFRE--EELRHQ 1370
Score = 49.7 bits (117), Expect = 4e-06
Identities = 40/145 (27%), Positives = 76/145 (52%), Gaps = 19/145 (13%)
Query: 151 GKEKEERDRLQ---LKALEELNQQLE------KRKEMEEREKRKIIAEE--KHKEWVQKK 199
GKE +DR Q + E ++QLE +R++ +E+E+ EE + +E ++++
Sbjct: 105 GKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQR 164
Query: 200 NEQKRKEREQKINKEMEEKAAKELEKEYLQ-----EKAKEKYQEWLKKKNAEECERKKKE 254
+ Q+R E + +E +E+ + E+E LQ E + +E L+++ E RK +E
Sbjct: 165 DRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGRE 224
Query: 255 KEKEKQQQAEIQEKKEIAEKKFQEW 279
EKQQQ ++ + E++ +EW
Sbjct: 225 ---EKQQQRRERQDRVFQEEEEKEW 246
Score = 48.5 bits (114), Expect = 1e-05
Identities = 44/207 (21%), Positives = 110/207 (53%), Gaps = 14/207 (6%)
Query: 73 QSFQFDEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQ 132
Q + D D E+E+ + +E D + E +V R E + + E + QE
Sbjct: 1406 QQLRQDRDRKFREEEQQLSRQER-DRKFREEEQQV---RRQERER-KFLEEEQQLRQERH 1460
Query: 133 KQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKH 192
++ R E L E + ++ERDR L+ ++L +Q E+ ++ E+E R ++E
Sbjct: 1461 RKFREEEQLLQEREEQQL--HRQERDRKFLEEEQQLRRQ-ERDRKFREQELR---SQEPE 1514
Query: 193 KEWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKE-KYQEWLKKKNAEECERK 251
+++++++ + R++R++K +E ++ +E ++ Q++ ++ + +E L+++ E+ +
Sbjct: 1515 RKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSR 1574
Query: 252 KKEKEKEKQQQAEIQEKKEIAEKKFQE 278
++ K + ++ +++ +++ E+KF E
Sbjct: 1575 QERDRKFRLEEQKVRRQEQ--ERKFME 1599
Score = 48.1 bits (113), Expect = 1e-05
Identities = 56/235 (23%), Positives = 110/235 (46%), Gaps = 36/235 (15%)
Query: 85 EDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQ---EEQKQVRLPESR 141
E+E + +E + HD + K + +G E ++ EE++Q+R E
Sbjct: 1647 EEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQER- 1705
Query: 142 LTPWEVWFIGKEKE-ERDRLQLKALEE--LNQQLEKRKEMEEREKRKIIAEEK----HKE 194
E F+ +E++ R L+ K EE L Q+ E+ + + RKI+ EE+ +E
Sbjct: 1706 ----ERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREE 1761
Query: 195 WVQKKNEQKRKER-EQKINKEMEEKA-------AKELEKEYLQEKAKE----------KY 236
++ E+ RK R E+++ +E EE+ K E+E L+++ +E KY
Sbjct: 1762 QQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKY 1821
Query: 237 ---QEWLKKKNAEECERKKKEKEKEKQQQAEIQEKKEIAEKKFQEWLENAKHKPR 288
+E L+ + E+ R++++++ ++Q QEK E++ + E + + R
Sbjct: 1822 RWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQER 1876
Score = 47.0 bits (110), Expect = 3e-05
Identities = 49/214 (22%), Positives = 102/214 (47%), Gaps = 33/214 (15%)
Query: 85 EDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPESRLTP 144
E EE+ ++E +E+ + ++ S R + Q Q+ESE + + K P +
Sbjct: 675 EHEEERREQELAEEEQEQARERIKS-RIPKWQW----QLESEADARQSKVYSRPRKQ--- 726
Query: 145 WEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKII----AEEKHKEWVQKKN 200
E +E+EE+ R + L+ ++ R++ EE ++R AEEK + Q+ +
Sbjct: 727 -EGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLS 785
Query: 201 E--------------QKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWL-KKKNA 245
++R++REQ+ E EEK E+ Q + +EK ++L +++
Sbjct: 786 ARPPLREQRERQLRAEERQQREQRFLPEEEEK-----EQRRRQRREREKELQFLEEEEQL 840
Query: 246 EECERKKKEKEKEKQQQAEIQEKKEIAEKKFQEW 279
+ ER ++ +E+E Q + + ++ +++ Q+W
Sbjct: 841 QRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKW 874
Score = 47.0 bits (110), Expect = 3e-05
Identities = 49/239 (20%), Positives = 110/239 (46%), Gaps = 17/239 (7%)
Query: 60 SNSTRSLLSPLGHQSFQFDEDDGDGEDEEDV---DDEEDVDEDAHDSEAKVASLRGMELQ 116
S + LL + + E D +EE + +E+ + D + + LR E Q
Sbjct: 1314 SQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQE-Q 1372
Query: 117 GCASTQVESENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRK 176
G + E ++E+++ L E + + +E++ R K EE Q + +
Sbjct: 1373 GRKFLEEEQRLRRQERERKFLKEEQQLRCQE----REQQLRQDRDRKFREEEQQLSRQER 1428
Query: 177 EMEEREKRKIIAEEKHKEWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKE-K 235
+ + RE+ + + ++ + ++ +Q R+ER +K + EE+ +E E++ L + ++ K
Sbjct: 1429 DRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFRE--EEQLLQEREEQQLHRQERDRK 1486
Query: 236 YQEWLKKKNAEECERKKKEKEKEKQQ------QAEIQEKKEIAEKKFQEWLENAKHKPR 288
+ E ++ +E +RK +E+E Q+ + E Q ++ ++KF + + + + R
Sbjct: 1487 FLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQER 1545
Score = 45.8 bits (107), Expect = 6e-05
Identities = 49/225 (21%), Positives = 108/225 (48%), Gaps = 20/225 (8%)
Query: 73 QSFQFDEDDGDGEDEEDVDDEEDVDEDAHDSEAKVAS----LRGMELQGCASTQVESENN 128
Q + D D E+E+ + + E+ + + K LR E + + +
Sbjct: 1659 QQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRR 1718
Query: 129 QEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKAL--EELNQQLEKR-KEMEEREKRK 185
QE +++ R E E + +++ R L+ + L E QQL ++ ++ + RE+ +
Sbjct: 1719 QELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQ 1778
Query: 186 IIAEEKHKEWVQKKNEQKRKEREQKINKEMEEKAAK----------ELEKEYLQEKAKEK 235
+ E + ++ +++++K +E EQ + +E EE+ + E E+ L+E+ +
Sbjct: 1779 LRQEREEQQLRSQESDRKFREEEQ-LRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRL 1837
Query: 236 YQEWLKKKNAEE--CERKKKEKEKEKQQQAEIQEKKEIAEKKFQE 278
QE ++ AEE ++K +E+++ Q E Q++++ E+K +E
Sbjct: 1838 RQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLRE 1882
Score = 45.4 bits (106), Expect = 8e-05
Identities = 43/175 (24%), Positives = 87/175 (49%), Gaps = 20/175 (11%)
Query: 124 ESENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKAL----EELNQQLEK--RKE 177
E QE ++Q R E + E + +E E+R R +L+ EEL Q+ E+ R+E
Sbjct: 1129 EKRRRQELERQYR-EEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREE 1187
Query: 178 MEEREKRKIIAEEKHKEWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQ 237
E+R + + E +++E ++ QKRK+R + ++ + K E EK E A +
Sbjct: 1188 QEKRRQER---ERQYRE-EEELQRQKRKQRYRDEDQRSDLKWQWEPEK----ENAVRDNK 1239
Query: 238 EWLKKKNAEECERKKKEKEKEKQQQAEIQ-----EKKEIAEKKFQEWLENAKHKP 287
+ K + E+ + + + +++Q Q ++Q +++ E++ + W + +H P
Sbjct: 1240 VYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFP 1294
Score = 42.7 bits (99), Expect = 5e-04
Identities = 27/126 (21%), Positives = 70/126 (55%), Gaps = 12/126 (9%)
Query: 151 GKEKEERDRLQLK-ALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQKKNEQKRKEREQ 209
G ++E+R R K +L + +Q E ++ E R+++ ++++ Q+R+++ Q
Sbjct: 94 GLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQ-----------LEEEPGQRRRQKRQ 142
Query: 210 KINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEECERKKKEKEKEKQQQAEIQEKK 269
+ +E+ E + ++E L+++ +++ E L ++ E ER+++ E+E+ Q + E +
Sbjct: 143 EQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETE 202
Query: 270 EIAEKK 275
E +++
Sbjct: 203 EFPDEE 208
Score = 42.7 bits (99), Expect = 5e-04
Identities = 33/122 (27%), Positives = 64/122 (52%), Gaps = 13/122 (10%)
Query: 114 ELQGCASTQVESENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLE 173
E Q S + + + +EEQ + E +L P + GK + E ++LQL EE Q+L
Sbjct: 1784 EEQQLRSQESDRKFREEEQLRQEREEQQLRPQQR--DGKYRWEEEQLQL---EEQEQRLR 1838
Query: 174 KRKEMEEREKRKIIAEEKHKEWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAK 233
+ ++ + R + + +EK + ++ ++ +E EQK +E E K L +E+++ + K
Sbjct: 1839 QERDRQYRAEEQFATQEKSR----REEQELWQEEEQKRRQERERK----LREEHIRRQQK 1890
Query: 234 EK 235
E+
Sbjct: 1891 EE 1892
Score = 37.7 bits (86), Expect = 0.017
Identities = 31/147 (21%), Positives = 64/147 (43%), Gaps = 4/147 (2%)
Query: 92 DEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPESRLTPWEVWFIG 151
D + +E+ E + LR + G + E +E+++++R R E F
Sbjct: 1794 DRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFAT 1853
Query: 152 KEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQKKNEQKRKEREQKI 211
+EK R+ +L EE ++ E+ +++ E R+ EE+ V + Q+ K + +
Sbjct: 1854 QEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQEGKGHGRLL 1913
Query: 212 NKEMEEKAAKELEK----EYLQEKAKE 234
+ A+ + EY+QE+ +
Sbjct: 1914 EPGTHQFASVPVRSSPLYEYIQEQRSQ 1940
Score = 31.2 bits (69), Expect = 1.6
Identities = 21/81 (25%), Positives = 46/81 (56%), Gaps = 3/81 (3%)
Query: 209 QKINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAE-ECERKKKEKEKEKQQQAEIQE 267
Q + E++A + ++ LQ++ +E+ Q + ++ + E E ++ ++K ++Q+ E+ E
Sbjct: 91 QATGLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAE 150
Query: 268 KKEIAEKKFQEWLENAKHKPR 288
+E +EK QE LE + R
Sbjct: 151 GEEQSEK--QERLEQRDRQRR 169
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 74.7 bits (182), Expect = 1e-13
Identities = 59/179 (32%), Positives = 95/179 (53%), Gaps = 14/179 (7%)
Query: 121 TQVESENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQL-KALEELNQQLEK-RKEM 178
TQ ESE +E +++ + R + KEK++R + + K E ++ EK RKE
Sbjct: 30 TQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKER 89
Query: 179 EEREKRKIIAEEKHKEWVQ-------KKNEQKRKEREQKINKEMEEK--AAKELEKEYLQ 229
E+E+RK E+K +E Q KK E+K +ERE K +E + K K+ KE +
Sbjct: 90 REKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKR 149
Query: 230 EKAKEKYQEWLKKKNAEECERKKKEKEKEKQQQAEIQEKKEIAEKKFQEWLENAKHKPR 288
EK + K + KK+ EE E+K++ KE++++ +E+KE E+K + E K K R
Sbjct: 150 EKERGKRERKRKKRKKEEREKKRERNRKERKKE---RERKERRERKKERKKERRKKKER 205
Score = 72.0 bits (175), Expect = 8e-13
Identities = 43/126 (34%), Positives = 75/126 (59%), Gaps = 3/126 (2%)
Query: 170 QQLEKRKEMEEREKRKIIAEEKHKEWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQ 229
++ E++KE EREKRK E++ K KK ++KRK+RE+ KE E K KE EK+ +
Sbjct: 32 RESERKKERREREKRKREREKERKRERGKKEKKKRKKRER--GKERERK-RKEREKQRKE 88
Query: 230 EKAKEKYQEWLKKKNAEECERKKKEKEKEKQQQAEIQEKKEIAEKKFQEWLENAKHKPRP 289
+ KE+ + +KK E +R ++E++K+K+++ +E K+ E+K ++ + + K R
Sbjct: 89 RREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERK 148
Query: 290 AAKSYG 295
K G
Sbjct: 149 REKERG 154
Score = 63.5 bits (153), Expect = 3e-10
Identities = 31/125 (24%), Positives = 73/125 (58%)
Query: 152 KEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQKKNEQKRKEREQKI 211
+E+++R R + K +E ++ + K+ ER+++K +++ KE ++K KR+ + +K
Sbjct: 104 RERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKR 163
Query: 212 NKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEECERKKKEKEKEKQQQAEIQEKKEI 271
KE EK + KE +E+ +++ +E K++ E ++K+++K+++ +Q + Q + +
Sbjct: 164 KKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQVFRPL 223
Query: 272 AEKKF 276
E F
Sbjct: 224 RESAF 228
Score = 63.2 bits (152), Expect = 4e-10
Identities = 37/133 (27%), Positives = 77/133 (57%), Gaps = 5/133 (3%)
Query: 152 KEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQKKNEQKRKEREQKI 211
KEK++R+R Q E ++ K +E E +++R E K K+ +KK ++RK +++
Sbjct: 99 KEKKKRERKQRGRRERKKKKERKERERENKQRR----ERKRKKRRKKKRRKERKREKERG 154
Query: 212 NKEMEEKAAKELEKEYLQEK-AKEKYQEWLKKKNAEECERKKKEKEKEKQQQAEIQEKKE 270
+E + K K+ E+E +E+ KE+ +E +K+ E + +KKE+ K+K+++ + + ++
Sbjct: 155 KRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQ 214
Query: 271 IAEKKFQEWLENA 283
+ F+ E+A
Sbjct: 215 TDSQVFRPLRESA 227
Score = 56.2 bits (134), Expect = 5e-08
Identities = 29/86 (33%), Positives = 56/86 (65%), Gaps = 7/86 (8%)
Query: 193 KEWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEECERKK 252
K Q+++E+K++ RE+ EK +E EKE +E+ K++ ++ K++ +E ERK+
Sbjct: 27 KPCTQRESERKKERRER-------EKRKREREKERKRERGKKEKKKRKKRERGKERERKR 79
Query: 253 KEKEKEKQQQAEIQEKKEIAEKKFQE 278
KE+EK+++++ E + +K EKK +E
Sbjct: 80 KEREKQRKERREKERRKRKKEKKKRE 105
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 73.9 bits (180), Expect = 2e-13
Identities = 40/132 (30%), Positives = 86/132 (65%), Gaps = 5/132 (3%)
Query: 152 KEKEERDRLQLKALEE--LNQQLEKRKEMEEREKRKIIAEEKHKEWVQKKNEQKRKEREQ 209
++KEER+R + + +E ++ EKRK+ E++E+ + E K +E +++ ++RKERE+
Sbjct: 90 RKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERER 149
Query: 210 K---INKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEECERKKKEKEKEKQQQAEIQ 266
K KE E K K+ E++ + EK +E+ ++ K++ E RK+++KE+E++++ E +
Sbjct: 150 KKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERK 209
Query: 267 EKKEIAEKKFQE 278
++++ E++ +E
Sbjct: 210 KERKKKEERKKE 221
Score = 73.9 bits (180), Expect = 2e-13
Identities = 49/161 (30%), Positives = 87/161 (54%), Gaps = 18/161 (11%)
Query: 124 ESENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREK 183
E EN + E+K+ R KEK+ER R + E ++ KR+E +ERE+
Sbjct: 103 EKENKEGEEKEKRKK-------------KEKKERGRTSKEGKERERKEERKREERKERER 149
Query: 184 RKIIAEEKHKEWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKK 243
+K EE+ KE +++ E+K++ER+Q KE E K + E++ + KE+ +E +K+
Sbjct: 150 KK---EEREKE--RERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKE 204
Query: 244 NAEECERKKKEKEKEKQQQAEIQEKKEIAEKKFQEWLENAK 284
E + +KK++E++K++Q + Q E+ +E E K
Sbjct: 205 RRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
Score = 72.0 bits (175), Expect = 8e-13
Identities = 55/231 (23%), Positives = 115/231 (49%), Gaps = 14/231 (6%)
Query: 57 LSCSNSTRSLLSPLGHQSFQFDEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQ 116
+SCS+ ++ P + E + + E + E + ++ + E + +
Sbjct: 20 VSCSHISKPCTQPGWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKR 79
Query: 117 GCASTQVESENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRK 176
+ + E +EE+++ + + KE EE+++ + K +E + ++ K
Sbjct: 80 ERGKKEKKGERKKEERERKKRRREKEN--------KEGEEKEKRKKKEKKERGRTSKEGK 131
Query: 177 EMEEREKRKIIAEEKHKEWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKY 236
E E +E+RK E+ KE +KK E++ KERE+K K+ E K E E+E +++ KE+
Sbjct: 132 ERERKEERK---REERKERERKK-EEREKERERKERKKRERKQVGEKEEERKEKERKERK 187
Query: 237 QEWLKKKNAEECERKKKEKEKEKQQQAEIQEKKEIAEKKFQ-EWLENAKHK 286
+ +K ++ ER++KE+ + K+++ + +E+K+ +K Q W E + K
Sbjct: 188 KRERNRKERKK-ERERKERRERKKERKKKEERKKERQKDRQTNWREKERGK 237
Score = 68.6 bits (166), Expect = 9e-12
Identities = 39/149 (26%), Positives = 86/149 (57%), Gaps = 12/149 (8%)
Query: 152 KEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQKKNEQKR------- 204
+EK +R+R + + E ++ + ++ EERE++K E+++KE +K+ +K+
Sbjct: 66 REKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGR 125
Query: 205 -----KEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEECERKKKEKEKEK 259
KERE+K ++ EE+ +E +KE +++ + K ++ ++K E E ++KEKE+++
Sbjct: 126 TSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKE 185
Query: 260 QQQAEIQEKKEIAEKKFQEWLENAKHKPR 288
+++ E K+ E++ +E E K + +
Sbjct: 186 RKKRERNRKERKKERERKERRERKKERKK 214
Score = 68.2 bits (165), Expect = 1e-11
Identities = 51/156 (32%), Positives = 88/156 (56%), Gaps = 21/156 (13%)
Query: 153 EKEERDR-LQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEW---VQKKNEQKRKERE 208
E ER+R ++ + + ++ E++KE EREKRK E++ K +KK E+K++ERE
Sbjct: 37 EIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERE 96
Query: 209 QKINK-EMEEKAAKELEKEYLQEKAKE----------KYQEWLKKKNAEECERKKKEKEK 257
+K + E E K +E EK +EK + + +E K++ +E ERKK+E+EK
Sbjct: 97 RKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREK 156
Query: 258 EKQQ-QAEIQEKKEIAEKKFQEWLENAKHKPRPAAK 292
E+++ + + +E+K++ EK+ E K K R K
Sbjct: 157 ERERKERKKRERKQVGEKE-----EERKEKERKERK 187
Score = 62.8 bits (151), Expect = 5e-10
Identities = 39/147 (26%), Positives = 83/147 (56%), Gaps = 6/147 (4%)
Query: 152 KEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQKKNEQKRKEREQ-- 209
K K ER++ + + + ++ E++KE ER+KR+ E K E +K+ ++++KER +
Sbjct: 68 KRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTS 127
Query: 210 KINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEECERK----KKEKEKEKQQQAEI 265
K KE E K ++ E+ +E+ KE+ ++ ++K ++ ERK K+E+ KEK+++
Sbjct: 128 KEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERK 187
Query: 266 QEKKEIAEKKFQEWLENAKHKPRPAAK 292
+ ++ E+K + + + + + K
Sbjct: 188 KRERNRKERKKERERKERRERKKERKK 214
Score = 50.4 bits (119), Expect = 3e-06
Identities = 34/120 (28%), Positives = 65/120 (54%), Gaps = 5/120 (4%)
Query: 175 RKEMEEREKRKIIAEEKHKEWVQKKNEQKRKEREQKINKEMEEKAAKEL--EKEYLQEKA 232
+ E+ ERE+ +E KE +++E+K++ RE++ K EK K +KE E+
Sbjct: 35 QSEIREREREIETRKEGKKE---RESERKKERREREKRKREREKERKRERGKKEKKGERK 91
Query: 233 KEKYQEWLKKKNAEECERKKKEKEKEKQQQAEIQEKKEIAEKKFQEWLENAKHKPRPAAK 292
KE+ + +++ E E ++KEK K+K+++ + KE E++ +E + + K R K
Sbjct: 92 KEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKK 151
Score = 40.8 bits (94), Expect = 0.002
Identities = 27/106 (25%), Positives = 52/106 (49%), Gaps = 15/106 (14%)
Query: 190 EKHKEWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEECE 249
E+ +E +K +K +E E+K + EK +E EKE +E+ K++
Sbjct: 40 EREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKE-------------- 85
Query: 250 RKKKEKEKEKQQQAEIQEKKEIAEKKFQEWLENAKHKPRPAAKSYG 295
KK E++KE++++ + + +KE E + +E + + K R G
Sbjct: 86 -KKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEG 130
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 72.4 bits (176), Expect = 6e-13
Identities = 61/226 (26%), Positives = 110/226 (48%), Gaps = 21/226 (9%)
Query: 73 QSFQFDEDDGD-GEDEEDV-DDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQE 130
Q Q E +G GE EE + + EE + + + +R E Q Q E QE
Sbjct: 190 QEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQ--MGEQEEQVQKQE 247
Query: 131 EQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEE 190
EQ Q + + R ++EE+ R Q + + E +Q+ K+KE E+E++ EE
Sbjct: 248 EQVQKQEEQMR-----------KQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEE 296
Query: 191 KHKEWVQKKNEQKRKEREQKIN-KEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEECE 249
+ +E ++ EQ+ + REQ+ +E EE+ K+ E+ + ++K Q W +K+ + E
Sbjct: 297 QMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMW-----EQKEQMWEQKEQMWKQE 351
Query: 250 RKKKEKEKEKQQQAEIQEKKEIAEKKFQEWLENAKHKPRPAAKSYG 295
+ E+E++ Q+Q E K+E +K +E + + + R + G
Sbjct: 352 EQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMG 397
Score = 68.2 bits (165), Expect = 1e-11
Identities = 59/224 (26%), Positives = 113/224 (50%), Gaps = 22/224 (9%)
Query: 70 LGHQSFQFDEDDGD-GEDEEDV--------DDEEDVDEDAHDSEAKVASLRGMELQGCAS 120
+G Q Q + + GE EE + + EE V + + + +R E Q
Sbjct: 208 MGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQ--MR 265
Query: 121 TQVESENNQEEQ--KQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEM 178
Q E QEEQ KQ E E +E+EE+ R Q + + E +Q+ +++E
Sbjct: 266 EQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQ 325
Query: 179 EEREKRKIIAEEKHKEWVQK----KNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKE 234
+++ ++ E+K + W QK K E++ E+E+++ K+ EE+ K+ E+ QE+
Sbjct: 326 MGKQEEQMW-EQKEQMWEQKEQMWKQEEQMGEQEEQMQKQ-EEQVRKQEEQMRKQEEQMR 383
Query: 235 KYQEWLKKKNAEECERKK---KEKEKEKQQQAEIQEKKEIAEKK 275
K +E ++K+ + E+K+ ++KE+ ++Q+ ++ E+KE K+
Sbjct: 384 KQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQ 427
Score = 64.7 bits (156), Expect = 1e-10
Identities = 48/200 (24%), Positives = 106/200 (53%), Gaps = 11/200 (5%)
Query: 73 QSFQFDEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQ 132
Q Q E +G ++E E++ + E +V G + + + +E++
Sbjct: 127 QEGQVREQEGQVREQEGQVREQE--GQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 184
Query: 133 KQVRLPESRLTPWEVWFIGKEKE--ERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEE 190
QVR E ++ E +E++ E++ K E++ +Q E+ ++ EE+ + +
Sbjct: 185 GQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQ 244
Query: 191 KHKEWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEECER 250
K +E VQK+ EQ RK+ EQ +E EE+ +E E++ L++K + + +E + E+ E+
Sbjct: 245 KQEEQVQKQEEQMRKQEEQM--REQEEQ-MREQEEQMLKQKEQTEQEE----QTGEQEEQ 297
Query: 251 KKKEKEKEKQQQAEIQEKKE 270
++++E+ ++Q+ +++E++E
Sbjct: 298 MREQEEQMREQEEQMREQEE 317
Score = 47.4 bits (111), Expect = 2e-05
Identities = 45/238 (18%), Positives = 106/238 (44%), Gaps = 3/238 (1%)
Query: 55 LPLSCSNSTRSLLSPLGHQSFQFDEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGME 114
+PL R + Q Q E +G ++E E++ + E +V G
Sbjct: 46 IPLPQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE--GQVREQEGQVREQEGQV 103
Query: 115 LQGCASTQVESENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEK 174
+ + + +E++ QVR E ++ E +E + R++ + + E+ Q E+
Sbjct: 104 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ-EGQVREQEGQVREQ 162
Query: 175 RKEMEEREKRKIIAEEKHKEWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKE 234
++ E+E + E + +E + EQ+ + EQ+ +E+ E E++ +++ +
Sbjct: 163 EGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQM 222
Query: 235 KYQEWLKKKNAEECERKKKEKEKEKQQQAEIQEKKEIAEKKFQEWLENAKHKPRPAAK 292
QE +K E+ ++++ +K+++Q + +E+ E++ +E E + + K
Sbjct: 223 GEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLK 280
Score = 35.8 bits (81), Expect = 0.064
Identities = 29/133 (21%), Positives = 73/133 (54%), Gaps = 7/133 (5%)
Query: 152 KEKEERDRLQLKALE--ELNQQLEKRKEMEEREKRKIIAEEKHKEWVQKKNEQKRKEREQ 209
K E ++ LQL E E+ +++ K E +K + E + +E + EQ+ + REQ
Sbjct: 12 KNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEGQVREQ 71
Query: 210 KINKEMEEKAAKELEKEYLQEKAKEKYQE-WLKKKNAEECERKKKEKEKE---KQQQAEI 265
+ +E +E E + +++ + + QE ++++ + E++ + +E+E ++Q+ ++
Sbjct: 72 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 131
Query: 266 QEKK-EIAEKKFQ 277
+E++ ++ E++ Q
Sbjct: 132 REQEGQVREQEGQ 144
Score = 35.0 bits (79), Expect = 0.11
Identities = 31/135 (22%), Positives = 73/135 (54%), Gaps = 16/135 (11%)
Query: 159 RLQLKALEELNQQLEKRKEMEEREKRKI---IAEEKHKEWVQK--------KNEQKRKER 207
R+ + L+E N +L++ ++ E EK +I I E K K K EQ+ + R
Sbjct: 3 RITNEELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVR 62
Query: 208 EQKINKEMEEKAAKELEKEYLQEKAKEKYQE-WLKKKNAEECERKKKEKEKE---KQQQA 263
EQ+ +E +E E + +++ + + QE ++++ + E++ + +E+E ++Q+
Sbjct: 63 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 122
Query: 264 EIQEKK-EIAEKKFQ 277
+++E++ ++ E++ Q
Sbjct: 123 QVREQEGQVREQEGQ 137
Score = 35.0 bits (79), Expect = 0.11
Identities = 34/157 (21%), Positives = 83/157 (52%), Gaps = 21/157 (13%)
Query: 126 ENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRK 185
E N E Q++++L E+ E+ +QL ++EL ++LE K +E +
Sbjct: 11 EKNAELQEELQLVET---------------EKSEIQLH-IKELKRKLETDKIPLPQEGQV 54
Query: 186 IIAEEKHKEWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQE-WLKKKN 244
E + +E + EQ+ + REQ+ +E +E E + +++ + + QE ++++
Sbjct: 55 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 114
Query: 245 AEECERKKKEKEKE---KQQQAEIQEKK-EIAEKKFQ 277
+ E++ + +E+E ++Q+ +++E++ ++ E++ Q
Sbjct: 115 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 151
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 71.6 bits (174), Expect = 1e-12
Identities = 61/207 (29%), Positives = 111/207 (53%), Gaps = 23/207 (11%)
Query: 85 EDEEDVDDEEDV----DEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPES 140
E EE + ++E+ +E + E K M Q + E + ++EQK +R E
Sbjct: 345 EQEEQMQEQEEKMWEQEEKMREQEEK------MWRQEERLWEQEKQMREQEQK-MRDQEE 397
Query: 141 RLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQKKN 200
R+ WE +EKEER R Q K E++ +++ + K+M+E+EK+ EEK +E + +
Sbjct: 398 RM--WEQDERLREKEERMREQEKMWEQV-EKMREEKKMQEQEKKTRDQEEKMQEEERIRE 454
Query: 201 EQKRKEREQKINKEMEEKAAK-------ELEKEYLQEKAKEKYQEWLKKKNAEECERKKK 253
+K+ E++ +E EEK K + EKE+ Q++ E+ ++ +++ +E E K
Sbjct: 455 REKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIW 514
Query: 254 EKEKEKQQQAEI--QEKKEIAEKKFQE 278
E+E++ + Q E+ QEKK ++K +E
Sbjct: 515 EQEEKIRDQEEMWGQEKKMWRQEKMRE 541
Score = 69.7 bits (169), Expect = 4e-12
Identities = 55/202 (27%), Positives = 109/202 (53%), Gaps = 15/202 (7%)
Query: 85 EDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPESRLTP 144
+ EE + +EE + E + ++R E + + E ++E +Q RLPE +
Sbjct: 441 DQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKL 500
Query: 145 WEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQKKNEQKR 204
WE + +E+EE+ Q + + + + + K+M +EK + E++ + W Q E+K
Sbjct: 501 WEQEKM-QEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMR---EQEDQMWEQ---EEKM 553
Query: 205 KEREQKI--NKEMEEKAAKELEKEYLQEKAKEKYQEWLK---KKNAEECERKKKEKEKEK 259
+++EQK+ +E EK +E EK+ ++ K + +E ++ KK EE E ++++EK +
Sbjct: 554 RDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQ 613
Query: 260 QQQAEIQEKKE---IAEKKFQE 278
+Q+ ++QE++E E+K QE
Sbjct: 614 EQEEKMQEQEEKMWEQEEKMQE 635
Score = 69.7 bits (169), Expect = 4e-12
Identities = 54/210 (25%), Positives = 110/210 (52%), Gaps = 14/210 (6%)
Query: 78 DEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRL 137
+++D E EE + D+E D + K + + E E +E +K++R
Sbjct: 541 EQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMRE 600
Query: 138 PESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEER--EKRKIIAEEKHKEW 195
E + E K +E+ +++Q + E++ +Q EK +E EE+ E+ + + E++ K W
Sbjct: 601 EEEMMREQEE----KMQEQEEKMQEQE-EKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMW 655
Query: 196 VQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQE-----WLKKKNAEECER 250
Q++ +++++ + + +EK ++ EK + QEK ++K QE W ++K EE
Sbjct: 656 EQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESM 715
Query: 251 KKKEKE--KEKQQQAEIQEKKEIAEKKFQE 278
+++EK+ +E++ E +EK + E+K QE
Sbjct: 716 REREKKMREEEEMMREQEEKMQEQEEKMQE 745
Score = 66.2 bits (160), Expect = 4e-11
Identities = 55/205 (26%), Positives = 105/205 (51%), Gaps = 12/205 (5%)
Query: 85 EDEEDVDDEEDVDEDAH---DSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPESR 141
E +E + ++E + E + E K+ M Q + E QE+Q + + R
Sbjct: 495 EQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMR 554
Query: 142 LTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQKKNE 201
++W + E++ + Q K + +++ + + M EREK+ EE +E +K E
Sbjct: 555 DQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQE 614
Query: 202 QKRKEREQKINK-EMEEKAAKELEKEYLQEKAKEKYQE--WLKKKNAEECER-----KKK 253
Q+ K +EQ+ E EEK ++ EK + QE+ + +E W +++ E+ E+ K +
Sbjct: 615 QEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQ 674
Query: 254 EKEKEKQQQAEIQEKKEIAEKKFQE 278
E+EK ++Q+ +I E++++ EKK QE
Sbjct: 675 EQEKMQEQEEKIWEQEKM-EKKTQE 698
Score = 66.2 bits (160), Expect = 4e-11
Identities = 51/209 (24%), Positives = 108/209 (51%), Gaps = 18/209 (8%)
Query: 85 EDEEDVDDEEDVDEDAH--DSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPESRL 142
++++ D EE + E+ + E K+ M + Q + E QE+++++ E ++
Sbjct: 574 QEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKM 633
Query: 143 TPWEVWFIGKEK----EERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQK 198
E +E+ +E + + L E ++L + ++M+E+EK + E++ K W Q+
Sbjct: 634 QEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQ---EQEEKIWEQE 690
Query: 199 KNEQKRKEREQKI--------NKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEECER 250
K E+K +E+E+K + M E+ K E+E + + +EK QE +K +E E
Sbjct: 691 KMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQE-EE 749
Query: 251 KKKEKEKEKQQQAEIQEKKEIAEKKFQEW 279
+++EK +Q+ ++ E++ + E+K + W
Sbjct: 750 MWEQEEKMWEQEEKMWEQQRLPEQKEKLW 778
Score = 64.7 bits (156), Expect = 1e-10
Identities = 49/185 (26%), Positives = 99/185 (53%), Gaps = 23/185 (12%)
Query: 124 ESENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREK 183
+ E +E++ ++R E ++ E +EKE R+ Q K L E + E+ ++M+E+E+
Sbjct: 298 QEERLREQEGKMREQEEKMWRQEKRLREQEKELRE--QEKELREQKELREQEEQMQEQEE 355
Query: 184 RKIIAEEKHKE------------WVQKK----NEQKRKEREQKINKEMEEKAAKELEKEY 227
+ EEK +E W Q+K EQK +++E+++ E +E+ ++ E+
Sbjct: 356 KMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERM-WEQDERLREKEERMR 414
Query: 228 LQEKAKEKYQEWLKKKNAEECERKKKEKEKEKQQQAEIQEKKEIAEKKFQEWLENAKHKP 287
QEK E+ ++ ++K +E E+K +++E++ Q++ I+E+ EKK +E E + +
Sbjct: 415 EQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIRER----EKKMREEEETMREQE 470
Query: 288 RPAAK 292
K
Sbjct: 471 EKMQK 475
Score = 64.3 bits (155), Expect = 2e-10
Identities = 50/211 (23%), Positives = 113/211 (53%), Gaps = 12/211 (5%)
Query: 73 QSFQFDEDDGDGEDEEDVDDEEDV----DEDAHDSEAKVASLRGMELQGCASTQVESENN 128
Q + E++ E E+ + +EE++ +E + E K+ + Q + E
Sbjct: 581 QEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKM 640
Query: 129 QEEQKQVRLPESRLTPWEVWFIGKEKEER-DRLQLKALEELNQQLEKRKEMEEREKRKII 187
E+++++ E ++ WE + ++KE+ + +++ E++ +Q EK E E+ EK+
Sbjct: 641 WEQEEKMWEQEEKM--WEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKT-- 696
Query: 188 AEEKHKEWVQKK--NEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQE-WLKKKN 244
E++ K W Q+K E+ +ERE+K+ +E E +E + + +EK +E+ +E W +++
Sbjct: 697 QEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEK 756
Query: 245 AEECERKKKEKEKEKQQQAEIQEKKEIAEKK 275
E E K E+++ +Q+ ++ E +++ E++
Sbjct: 757 MWEQEEKMWEQQRLPEQKEKLWEHEKMQEQE 787
Score = 63.5 bits (153), Expect = 3e-10
Identities = 54/198 (27%), Positives = 109/198 (55%), Gaps = 20/198 (10%)
Query: 85 EDEEDVDDEED----VDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPES 140
E E+ + D+E+ DE + E ++ M Q E + QE++K+ R E
Sbjct: 387 EQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQ--VEKMREEKKMQEQEKKTRDQEE 444
Query: 141 RLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKE----MEERE-KRKIIAEEKHKEW 195
++ E +E+E++ R + + + E ++++K++E EE+E +++ + E+K K W
Sbjct: 445 KMQEEERI---REREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLW 501
Query: 196 VQKK---NEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKY-QEWLKKKNAEECERK 251
Q+K E+K E+E+KI ++ EE +E +K + QEK +E+ Q W +++ + E+K
Sbjct: 502 EQEKMQEQEEKIWEQEEKI-RDQEEMWGQE-KKMWRQEKMREQEDQMWEQEEKMRDQEQK 559
Query: 252 KKEKEKEKQQQAEIQEKK 269
++E+ +++ + QEKK
Sbjct: 560 MWDQEERMEKKTQEQEKK 577
Score = 63.2 bits (152), Expect = 4e-10
Identities = 55/216 (25%), Positives = 120/216 (55%), Gaps = 16/216 (7%)
Query: 78 DEDDGDGEDEEDVDDE-EDVDEDAHDSEAKVASLRGM-ELQGCASTQVESENNQEEQKQV 135
D++ + EE ++ + ++ ++ D E K+ M E + + E QEE+ Q
Sbjct: 555 DQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQE 614
Query: 136 RLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEERE-KRKIIAEEKHKE 194
+ + + ++W E+ +++Q + E++ +Q EK E EE+ +++ + E+K K
Sbjct: 615 QEEKMQEQEEKMW------EQEEKMQ-EQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKL 667
Query: 195 WVQKK--NEQKRKEREQKI--NKEMEEKAAKELEKEYLQEKAK-EKYQEWLKKKNAEECE 249
W +K ++K +E+E+KI ++ME+K ++ +K + QEK + E+ +KK EE E
Sbjct: 668 WEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEE 727
Query: 250 RKKKEKEKEKQQQAEIQE-KKEIAEKKFQEWLENAK 284
++++EK ++Q+ ++QE ++E+ E++ + W + K
Sbjct: 728 MMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEK 763
Score = 62.0 bits (149), Expect = 8e-10
Identities = 42/164 (25%), Positives = 97/164 (59%), Gaps = 7/164 (4%)
Query: 124 ESENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQL-EKRKEMEERE 182
+ E +E+++++ E RL WE +E+E++ R Q + + E +++L EK + M E+E
Sbjct: 360 QEEKMREQEEKMWRQEERL--WEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQE 417
Query: 183 KRKIIAEEKHKEWVQKKNEQKRKEREQKINKE--MEEKAAKELEKEYLQEKAKEKYQEWL 240
K E+ +E ++ E+K +++E+K+ +E + E+ K E+E + +EK Q+
Sbjct: 418 KMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQK-- 475
Query: 241 KKKNAEECERKKKEKEKEKQQQAEIQEKKEIAEKKFQEWLENAK 284
+++N E E K+ ++++ +Q+ ++ E++++ E++ + W + K
Sbjct: 476 QEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEK 519
Score = 62.0 bits (149), Expect = 8e-10
Identities = 52/223 (23%), Positives = 112/223 (50%), Gaps = 25/223 (11%)
Query: 70 LGHQSFQFDEDDGDGEDEEDVDDEEDV---------DEDAHDSEAKVASLRGMELQGCAS 120
L Q ++++ E EE + D+E++ E + E ++ E +
Sbjct: 500 LWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQM-----WEQEEKMR 554
Query: 121 TQVESENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEE 180
Q + +QEE+ + + E W+ +E+E + K EE E+ ++M+E
Sbjct: 555 DQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQE 614
Query: 181 REKRKIIAEEKHKEWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWL 240
+E++ + E++ K W Q E+K +E+E+K+ E EEK ++ EK + Q++ E+ ++
Sbjct: 615 QEEK--MQEQEEKMWEQ---EEKMQEQEEKM-WEQEEKMWEQEEKMWEQQRLPEQKEKLW 668
Query: 241 KKKNAEECERKKKEKEK-----EKQQQAEIQEKKEIAEKKFQE 278
+ + +E E+ ++++EK + +++ + QEKK ++K +E
Sbjct: 669 EHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMRE 711
Score = 61.6 bits (148), Expect = 1e-09
Identities = 46/164 (28%), Positives = 94/164 (57%), Gaps = 15/164 (9%)
Query: 124 ESENNQEEQKQVRLPESRLTPWE--VWFIGKEKEERDRLQLKALEELNQQL-EKRKEMEE 180
E E EQK++R E ++ E +W E+EE+ R Q + + ++L E+ K+M E
Sbjct: 332 EQEKELREQKELREQEEQMQEQEEKMW----EQEEKMREQEEKMWRQEERLWEQEKQMRE 387
Query: 181 REKRKIIAEEKHKEWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQE---KAKEKYQ 237
+E++ EE+ E ++ E++ + REQ+ +M E+ K E++ +QE K +++ +
Sbjct: 388 QEQKMRDQEERMWEQDERLREKEERMREQE---KMWEQVEKMREEKKMQEQEKKTRDQEE 444
Query: 238 EWLKKKNAEECERKKKEKEKEKQQQAEIQEKKE--IAEKKFQEW 279
+ +++ E E+K +E+E+ ++Q E +K+E + E++ +EW
Sbjct: 445 KMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEW 488
Score = 61.2 bits (147), Expect = 1e-09
Identities = 55/225 (24%), Positives = 118/225 (52%), Gaps = 17/225 (7%)
Query: 77 FDEDDGDGEDEEDVDDEEDVDEDAHDS-EAKVASLRGMELQGCASTQVESENNQEEQKQV 135
+++D+ E EE + ++E + E E K + + + E E +E +K++
Sbjct: 400 WEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKM 459
Query: 136 RLPESRLTPWEVWFIGKEK----EERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEK 191
R E + E +E+ +E Q + L E ++L ++++M+E+E++ EEK
Sbjct: 460 REEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEK 519
Query: 192 HKE----WVQKK---NEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKN 244
++ W Q+K ++K +E+E ++ E EEK + +K + QE+ EK + +KK
Sbjct: 520 IRDQEEMWGQEKKMWRQEKMREQEDQM-WEQEEKMRDQEQKMWDQEERMEKKTQEQEKKT 578
Query: 245 AEECERKKKEKEKEKQQQAEIQEKKEI---AEKKFQEWLENAKHK 286
++ E K +E+E+ ++++ +++E++E+ E+K QE E + +
Sbjct: 579 WDQ-EEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQ 622
Score = 57.0 bits (136), Expect = 3e-08
Identities = 46/181 (25%), Positives = 99/181 (54%), Gaps = 22/181 (12%)
Query: 124 ESENNQEEQKQVRLPESRLTPWEVWFI---GKEKEERDRL--QLKALEELNQQLEKRKEM 178
+ E +E++K++R E ++ E GK +E+ +++ Q K L E ++L + +E
Sbjct: 277 QEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKEL-REQEK 335
Query: 179 EEREKRKIIAEEKHKEWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQE 238
E RE++++ +E+ + + E+K E+E+K+ +E EEK ++ E+ + QEK + ++
Sbjct: 336 ELREQKELREQEEQMQ----EQEEKMWEQEEKM-REQEEKMWRQEERLWEQEKQMREQEQ 390
Query: 239 ---------WLKKKNAEECERKKKEKEKEKQQQAEIQEKKEI--AEKKFQEWLENAKHKP 287
W + + E E + +E+EK +Q +++E+K++ EKK ++ E + +
Sbjct: 391 KMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEE 450
Query: 288 R 288
R
Sbjct: 451 R 451
Score = 55.1 bits (131), Expect = 1e-07
Identities = 53/198 (26%), Positives = 97/198 (48%), Gaps = 6/198 (3%)
Query: 73 QSFQFDEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQ 132
+ Q E+ ++E+ + EE + E E K ++Q Q + E E++
Sbjct: 631 EKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQE 690
Query: 133 K-QVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEK 191
K + + E W+ + +E+ R+R + K EE E+ ++M+E+E++ EE+
Sbjct: 691 KMEKKTQEQEKKTWDQEKMREEESMRER-EKKMREEEEMMREQEEKMQEQEEKMQEQEEE 749
Query: 192 HKEWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEECERK 251
E +K EQ+ K EQ+ E +EK E E +QE+ K QE K ++ EE R
Sbjct: 750 MWEQEEKMWEQEEKMWEQQRLPEQKEKL---WEHEKMQEQEKIWEQE-EKMRDQEEKMRG 805
Query: 252 KKEKEKEKQQQAEIQEKK 269
++EK + ++++ QE+K
Sbjct: 806 QEEKMRGQEEKMRGQEEK 823
Score = 53.9 bits (128), Expect = 2e-07
Identities = 47/165 (28%), Positives = 90/165 (54%), Gaps = 18/165 (10%)
Query: 126 ENNQEEQKQVRLPESRLTPWEVWFIGKE---KEERDRLQLKALEELNQQLEK-RKEMEER 181
+ N E Q+++ L ES + E+ KE K ER + L ++ Q E R+E E R
Sbjct: 225 KKNAELQEKLPLAESEKS--EIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELR 282
Query: 182 EKRKIIAEEKHKEWVQKKN--EQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEW 239
E+ K I +++ K W Q++ EQ+ K REQ+ +EK +E EKE L+E+ KE
Sbjct: 283 EQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKE-LREQEKEL---- 337
Query: 240 LKKKNAEECERKKKEKEKEKQQQAEIQEKKEIAEKKFQEWLENAK 284
E+ E +++E++ ++Q++ ++++++ E++ + W + +
Sbjct: 338 -----REQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEER 377
Score = 53.1 bits (126), Expect = 4e-07
Identities = 45/195 (23%), Positives = 105/195 (53%), Gaps = 12/195 (6%)
Query: 85 EDEEDVDDEEDV--DEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPESRL 142
E E+ D+E + +E + E K+ M + Q + E QE+++++ E ++
Sbjct: 698 EQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKM 757
Query: 143 TPWE----VWFIGKEKEERDRL-QLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQ 197
WE +W + E++++L + + ++E + E+ ++M ++E++ EEK + +
Sbjct: 758 --WEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEE 815
Query: 198 KKNEQKRKE--REQKINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEECERKKKEK 255
K Q+ K +E+K+ + EEK + EK + QE+ E+ + ++K E+ E+ + ++
Sbjct: 816 KMRGQEEKMWGQEEKMWGQ-EEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQE 874
Query: 256 EKEKQQQAEIQEKKE 270
EK ++Q+ +++ ++E
Sbjct: 875 EKMREQEEKMRGQEE 889
Score = 51.2 bits (121), Expect = 1e-06
Identities = 53/216 (24%), Positives = 104/216 (48%), Gaps = 20/216 (9%)
Query: 72 HQSFQFDEDDGDGEDEEDVDDEEDVDEDAHDSEAKV---------ASLRGMELQGCASTQ 122
H+ Q E + E EE + ++E +++ + E K S+R E + +
Sbjct: 670 HEKMQ--EQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEE 727
Query: 123 VESENNQEEQKQV-RLPESRLTPWE----VWFIGKEKEERDRL--QLKALEELNQQLEKR 175
+ E ++ Q+Q ++ E WE +W ++ E+ RL Q + L E + E+
Sbjct: 728 MMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQE 787
Query: 176 KEMEEREKRKIIAEEKHKEWVQKKNEQKRKEREQKINK-EMEEKAAKELEKEYLQEKAKE 234
K E+ EK + EEK + +K Q+ K R Q+ EEK + EK + QE+
Sbjct: 788 KIWEQEEKMR-DQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMW 846
Query: 235 KYQEWLKKKNAEECERKKKEKEKEKQQQAEIQEKKE 270
+E +++K + E+ ++++EK + Q+ +++E++E
Sbjct: 847 GQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEE 882
Score = 50.1 bits (118), Expect = 3e-06
Identities = 39/152 (25%), Positives = 81/152 (53%), Gaps = 23/152 (15%)
Query: 149 FIGKEKEERDRLQLKA---------LEELNQQLEKRKEMEEREKRKI---IAEEKHK--- 193
+I + +ERD L L+ L++ N +L+++ + E EK +I + E K K
Sbjct: 198 YIEELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLER 257
Query: 194 -----EWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEEC 248
VQ Q+ R+++ +E E+K K+ EK + QE+ + + ++++ +
Sbjct: 258 AKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMW 317
Query: 249 ERKKKEKEKEK---QQQAEIQEKKEIAEKKFQ 277
++K+ +E+EK +Q+ E++E+KE+ E++ Q
Sbjct: 318 RQEKRLREQEKELREQEKELREQKELREQEEQ 349
Score = 38.9 bits (89), Expect = 0.008
Identities = 48/191 (25%), Positives = 84/191 (43%), Gaps = 51/191 (26%)
Query: 79 EDDGDGEDEEDVDDEEDV----DEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQ-- 132
E++ E E+ + +EE++ +E + E K+ E + Q E QEE+
Sbjct: 711 EEESMREREKKMREEEEMMREQEEKMQEQEEKM-----QEQEEEMWEQEEKMWEQEEKMW 765
Query: 133 KQVRLPESRLTPWE---------VWFIGKEKEERDRLQLKAL----EELNQQLEKRKEME 179
+Q RLPE + WE +W E+EE+ R Q + + E++ Q EK + E
Sbjct: 766 EQQRLPEQKEKLWEHEKMQEQEKIW----EQEEKMRDQEEKMRGQEEKMRGQEEKMRGQE 821
Query: 180 ER-----------------EKRKIIAEEKHKEWVQKKNEQKRKEREQKIN------KEME 216
E+ ++ K+ +E+ E + E+K +E+E+K+ +E E
Sbjct: 822 EKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQE 881
Query: 217 EKAAKELEKEY 227
EK + EK Y
Sbjct: 882 EKMRGQEEKIY 892
Score = 28.9 bits (63), Expect = 7.8
Identities = 20/61 (32%), Positives = 31/61 (50%), Gaps = 2/61 (3%)
Query: 230 EKAKEKYQEWLKKKNAEECE--RKKKEKEKEKQQQAEIQEKKEIAEKKFQEWLENAKHKP 287
+KA +E K+++A E R E+ K++ AE+QEK +AE + E N K
Sbjct: 193 KKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKELK 252
Query: 288 R 288
R
Sbjct: 253 R 253
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 71.2 bits (173), Expect = 1e-12
Identities = 66/239 (27%), Positives = 117/239 (48%), Gaps = 22/239 (9%)
Query: 70 LGHQSFQFDEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRG-MELQGCASTQVESENN 128
+ H +ED E E + E+ + + + K+A R +E + A+ Q
Sbjct: 251 ISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERRE 310
Query: 129 QEEQKQVRLPESRLTPWEVWFIGKEK---EERDRLQLKALEELNQQLEKRKEMEEREKRK 185
EE++++R E R +EK EER R++ EE + E+R+ ++E EKR
Sbjct: 311 AEERERMREEEKRAAEERQRIKEEEKRAAEERQRIK----EEEKRAAEERQRIKEEEKR- 365
Query: 186 IIAEEKHKEWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQ-EWLKKKN 244
AEE+ + + + E+K K EQK NK++EEK E + EK ++K + +W+ +K
Sbjct: 366 -AAEERQR--ARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKK 422
Query: 245 AEE-----CERKKKEKEKEKQQQAEIQEKKEIAEKKFQEWLENAKHK----PRPAAKSY 294
A+E KK+ +EK + QA+ ++ +E +E +++ K K P+ KS+
Sbjct: 423 AQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSF 481
Score = 65.5 bits (158), Expect = 8e-11
Identities = 56/203 (27%), Positives = 102/203 (50%), Gaps = 21/203 (10%)
Query: 79 EDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQ---VESENNQEEQKQV 135
E++ + +E E+ +ED +EA+ A L E + + Q + E + E ++
Sbjct: 241 EEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEK 300
Query: 136 RLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEW 195
+ R +E EER+R++ EE + E+R+ ++E EKR AEE+ +
Sbjct: 301 AAAQERER--------REAEERERMR----EEEKRAAEERQRIKEEEKRA--AEERQRI- 345
Query: 196 VQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEECERKKKEK 255
K E+KR E++ KE E++AA+E ++ +E+ K K +E + K EE + +E
Sbjct: 346 ---KEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQET 402
Query: 256 EKEKQQQAEIQEKKEIAEKKFQE 278
+ + ++ + E K + EKK QE
Sbjct: 403 KIKGEKVEQKIEGKWVNEKKAQE 425
Score = 63.2 bits (152), Expect = 4e-10
Identities = 55/227 (24%), Positives = 113/227 (49%), Gaps = 27/227 (11%)
Query: 78 DEDDGDGEDEEDVDDEEDVDEDAHDSEAKVA---------SLRGMELQGCASTQVESENN 128
D ++ ED+E ++EE+ + E +V S + + Q+ SE
Sbjct: 179 DAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEP 238
Query: 129 QEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIA 188
++E+++ + + ++ KE+ E +R +L+A E + E+ K++ + E+ +I A
Sbjct: 239 KQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIAD-ERARIEA 297
Query: 189 EEKH----------KEWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQE 238
EEK +E + + E+KR E++ KE E++AA+E ++ +EK + ++
Sbjct: 298 EEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQ 357
Query: 239 WLKKKNAEECERKKKEKEKEKQQQAEIQEKKEIAEKKFQEWLENAKH 285
+K E +K+ E+ ++ +AE +EK ++ E+K + LE KH
Sbjct: 358 RIK-------EEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKH 397
Score = 55.1 bits (131), Expect = 1e-07
Identities = 38/224 (16%), Positives = 107/224 (47%), Gaps = 2/224 (0%)
Query: 70 LGHQSFQFDEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQ 129
L + Q D + + ++E+ + + ++E S + + + + E + +
Sbjct: 132 LPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKE 191
Query: 130 EEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAE 189
EE+++ + + +V + +EK + + + N Q+ + +E E+ + E
Sbjct: 192 EEEEE-KPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDE 250
Query: 190 EKHKEWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEECE 249
H E ++++++++ + ++ E E+ E +K+ E+A+ + +E + E E
Sbjct: 251 ISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERRE 310
Query: 250 RKKKEKEKEKQQQ-AEIQEKKEIAEKKFQEWLENAKHKPRPAAK 292
+++E+ +E++++ AE +++ + EK+ E + K + + AA+
Sbjct: 311 AEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAE 354
Score = 52.4 bits (124), Expect = 7e-07
Identities = 41/207 (19%), Positives = 93/207 (44%), Gaps = 13/207 (6%)
Query: 85 EDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPESRLTP 144
ED+ EE DE + ++ + T+V+S+N + +++ E+ +
Sbjct: 453 EDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSR 512
Query: 145 WEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQKKNEQKR 204
KE Q++A + L + +R E E E K+ +++ ++ ++KR
Sbjct: 513 PGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKR 572
Query: 205 KEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEECERKKKEKE-------- 256
+ER + + +E + + +E +++ +E+ K + +E ++++ AE E+++K E
Sbjct: 573 EERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKK 632
Query: 257 -----KEKQQQAEIQEKKEIAEKKFQE 278
K +I+E+ E K Q+
Sbjct: 633 PFKCFTPKGSSLKIEERAEFLNKSVQK 659
Score = 50.1 bits (118), Expect = 3e-06
Identities = 45/181 (24%), Positives = 86/181 (47%), Gaps = 16/181 (8%)
Query: 124 ESENNQEEQKQVRLPESRLTPWEVWFIGKEKEE---RDRLQLKALEELNQQLEKRKEMEE 180
E + EE+++++ E R +E+E+ ++ + K LEE +++ K E
Sbjct: 348 EEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGE 407
Query: 181 REKRKIIAEEKHKEWVQKKNEQKRKEREQKINKEMEEKAAK-ELEKEYLQEKAKEKYQEW 239
+ ++KI +WV +K Q+ K + + K+ EEK K + ++E LQE +E
Sbjct: 408 KVEQKI-----EGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEE 462
Query: 240 LKKKNAEECERKKKEKEKEKQQQAEIQEKKEIAEKKFQEWLENAKHKPRPAAKSYGYANG 299
+K E+ KK+KE +++ ++ + KK E K Q E HK + ++ G
Sbjct: 463 IKD------EKIKKDKEPKEEVKSFMDRKKGFTEVKSQNG-EFMTHKLKHTENTFSRPGG 515
Query: 300 K 300
+
Sbjct: 516 R 516
Score = 44.3 bits (103), Expect = 2e-04
Identities = 29/112 (25%), Positives = 64/112 (57%), Gaps = 15/112 (13%)
Query: 171 QLEKRKEMEEREKRKIIAEEKHKEWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQE 230
Q+E K +EE +R+ E + +E+ +K K+++Q+ E+EE K E+ + E
Sbjct: 529 QVEAGKRLEELRRRR--GETESEEF------EKLKQKQQEAALELEELKKKREERRKVLE 580
Query: 231 KAKEKYQEWLKKKNAEECERKKKEKEKEKQQQAEIQEKKEIAEKKFQEWLEN 282
+ +++ ++ EE +RK +E+E++++ + EI+ ++ A +K Q+ E+
Sbjct: 581 EEEQRRKQ-------EEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPED 625
Score = 42.4 bits (98), Expect = 7e-04
Identities = 47/219 (21%), Positives = 94/219 (42%), Gaps = 23/219 (10%)
Query: 87 EEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPESRLTPWE 146
E+ ++ + ++ A + + + A L+ + Q + E QE++ + E +
Sbjct: 410 EQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEK-- 467
Query: 147 VWFIGKEKEERDRLQL-----KALEELNQQ-----LEKRKEMEEREKR---KIIAEEKHK 193
I K+KE ++ ++ K E+ Q K K E R + + K
Sbjct: 468 ---IKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEA 524
Query: 194 EWVQ-----KKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEEC 248
E K+ E+ R+ R + ++E E+ K+ E E+ K+K +E K EE
Sbjct: 525 EGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQ 584
Query: 249 ERKKKEKEKEKQQQAEIQEKKEIAEKKFQEWLENAKHKP 287
RK++E +++ +++ E + KE E++ E E + P
Sbjct: 585 RRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMP 623
Score = 37.0 bits (84), Expect = 0.029
Identities = 38/165 (23%), Positives = 81/165 (49%), Gaps = 11/165 (6%)
Query: 108 ASLRGMELQGCASTQVESENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEE 167
AS+ E +G + QVE+ EE ++ R E+ +E K+K++ L+L+ L++
Sbjct: 517 ASVDTKEAEG--APQVEAGKRLEELRR-RRGETESEEFEKL---KQKQQEAALELEELKK 570
Query: 168 LNQQLEKRKEMEEREKRKIIAEEKHKEWVQKKNEQKRKEREQKINKEMEEKAAKELEKEY 227
+ E+RK +EE E+R+ E K ++ E+KR+ +E+ + E ++ E
Sbjct: 571 KRE--ERRKVLEEEEQRRKQEEADRK---LREEEEKRRLKEEIERRRAEAAEKRQKMPED 625
Query: 228 LQEKAKEKYQEWLKKKNAEECERKKKEKEKEKQQQAEIQEKKEIA 272
K+ ++ + K ++ + E + + K Q+ + ++ + A
Sbjct: 626 GLSDDKKPFKCFTPKGSSLKIEERAEFLNKSVQKSSGVKSTHQAA 670
Score = 35.4 bits (80), Expect = 0.083
Identities = 42/197 (21%), Positives = 83/197 (42%), Gaps = 24/197 (12%)
Query: 76 QFDEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQV 135
Q +E G D+ +V+ + V D EAK + + +E +EE++Q
Sbjct: 54 QEEESLGQVTDQVEVNAQNSVP----DEEAKTTTTNTQVEGDDEAAFLERLARREERRQK 109
Query: 136 RLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEW 195
RL E+ ER + + + + L R+ + + + +E+ E
Sbjct: 110 RLQEAL--------------ERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSES 155
Query: 196 VQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNA---EECERKK 252
Q++ E + E K ++ + + A+E +KE +K KE+ +E K+ + + E
Sbjct: 156 RQERYEIEETETVTKSYQKNDWRDAEENKKE---DKEKEEEEEEKPKRGSIGENQVEVMV 212
Query: 253 KEKEKEKQQQAEIQEKK 269
+EK E Q++ + K
Sbjct: 213 EEKTTESQEETVVMSLK 229
Score = 33.9 bits (76), Expect = 0.24
Identities = 30/115 (26%), Positives = 55/115 (47%), Gaps = 20/115 (17%)
Query: 190 EKHKEWVQKKNEQKRKEREQ---KINKEMEEKAAKELEKEYLQEKAKEKYQE-------- 238
E+ +E ++K E+ R E E+ + N + EE+AA+E + QE+ ++K +E
Sbjct: 5 ERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTD 64
Query: 239 --WLKKKNA---EECERKKKEKEKEKQQQAEIQE----KKEIAEKKFQEWLENAK 284
+ +N+ EE + + E +A E ++E +K+ QE LE K
Sbjct: 65 QVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQK 119
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 69.3 bits (168), Expect = 5e-12
Identities = 55/192 (28%), Positives = 102/192 (53%), Gaps = 11/192 (5%)
Query: 83 DGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQV---ESENNQEEQKQVRLPE 139
D E+E +++EE + + + RG + + S+QV ESE + E+ + L E
Sbjct: 2177 DDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDE 2236
Query: 140 SRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQKK 199
+ +E+EER+ + + EE+ ++ E+RKE EE E++++ EE+ K +KK
Sbjct: 2237 LEK---QESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEK---KKK 2290
Query: 200 NEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEECERKKKEKEKEK 259
++K+KE Q+ + EEK +E+ E E ++ +E EE +R+K+ +KEK
Sbjct: 2291 KKEKKKEEVQEKEEVFEEK--EEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEK 2348
Query: 260 QQQAEIQEKKEI 271
Q + + Q +K +
Sbjct: 2349 QFKLQEQRRKSL 2360
Score = 60.5 bits (145), Expect = 2e-09
Identities = 42/130 (32%), Positives = 75/130 (57%), Gaps = 9/130 (6%)
Query: 165 LEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQKKNEQKRKEREQ----KINKEMEE--K 218
+E L +LEK++ + E+ + EE+ +E ++ E++RKE E+ ++ KE EE K
Sbjct: 2230 MESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKK 2289
Query: 219 AAKELEKEYLQEKAKEKYQEWLKKKNAEECERKKKEKEKEK--QQQAEIQEKKEIAEKKF 276
KE +KE +QEK +E ++E + + EE E E+E+E+ + E+ +KEI +K+
Sbjct: 2290 KKKEKKKEEVQEK-EEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEK 2348
Query: 277 QEWLENAKHK 286
Q L+ + K
Sbjct: 2349 QFKLQEQRRK 2358
Score = 59.7 bits (143), Expect = 4e-09
Identities = 44/152 (28%), Positives = 81/152 (53%), Gaps = 21/152 (13%)
Query: 124 ESENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREK 183
E E EE++ + + R W KE + D+ + K ++++ + EE E
Sbjct: 2179 EEEGGIEEEEVIPFLKRR------WRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMES 2232
Query: 184 RKIIAEEKHKEWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKK 243
++ E + +E + + E++R+E E++ +E+ E+ + E+E +EK EK
Sbjct: 2233 --LLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEK-------- 2282
Query: 244 NAEECERKKKEKEKEKQQQAEIQEKKEIAEKK 275
EE E+KKK+KEK+K+ E+QEK+E+ E+K
Sbjct: 2283 --EEEEKKKKKKEKKKE---EVQEKEEVFEEK 2309
Score = 54.7 bits (130), Expect = 1e-07
Identities = 45/147 (30%), Positives = 74/147 (50%), Gaps = 13/147 (8%)
Query: 124 ESENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREK 183
E E NQEE K V + +L E+EE Q + L E +L + +E+ +EK
Sbjct: 1732 EEELNQEEGKLVE-EKKKLA---------EEEEALAWQREKLSEEETKLAQEEELLIQEK 1781
Query: 184 RKIIAEEKHKEWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKK 243
K+ +HKE + ++ E+ ++REQ I K+M+ +E ++E K K + KK
Sbjct: 1782 EKL---AQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKN 1838
Query: 244 NAEECERKKKEKEKEKQQQAEIQEKKE 270
A+E + +EKEK Q++ + KE
Sbjct: 1839 LAQEKKNLAQEKEKLAQRKENLLYNKE 1865
Score = 52.4 bits (124), Expect = 7e-07
Identities = 61/210 (29%), Positives = 112/210 (53%), Gaps = 36/210 (17%)
Query: 87 EEDVDDEEDVDEDAHDSEAKVASLRG--MELQGCASTQVESENNQEEQKQVRLPESRLTP 144
+E+ D E+V+E A E KV G + ++ S Q + + +E KQV E+R +
Sbjct: 1422 KEERDMSEEVEEMA-TLEEKVVKQEGKLVMIERTPSWQ-DWKKAWDEWKQVH-GETRKS- 1477
Query: 145 WEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEE--REKRKIIAEEKHKEWVQ----- 197
W+ W KEE ++ L+ E+L+Q EK EE +E +K+ K +EW Q
Sbjct: 1478 WKAW-----KEEWEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKL----KWEEWKQVWENM 1528
Query: 198 ---KKNEQKRKER-----EQKINKEMEEKAAKELEKE-YLQEKAK----EKYQEWLKKKN 244
K EQ+ K+ E+++++E EEK + E++ ++QE+ K + + +KK
Sbjct: 1529 LSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKR 1588
Query: 245 AEECERKKKEKEKEKQQQAEI-QEKKEIAE 273
A+E + +E+EK Q++ ++ QE++++A+
Sbjct: 1589 AQEERKLAQEEEKLAQEERQLAQEERKLAQ 1618
Score = 52.0 bits (123), Expect = 9e-07
Identities = 51/183 (27%), Positives = 100/183 (54%), Gaps = 23/183 (12%)
Query: 126 ENNQEEQKQVRLPESRLTPWEVWFIGKEKEE--RDRLQLKALEELNQQLEKRKEMEEREK 183
E +E K+++ E + WE K KE+ +D ++ EE++++ E++++ E+
Sbjct: 1507 EEMLQEDKKLKWEEWKQV-WENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQ 1565
Query: 184 RKIIAEEKHKEWV-----QKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQE 238
R I +E+HK W + + E+KR + E+K+ +E EEK A+E E++ QE+ K Q
Sbjct: 1566 RHI--QEEHK-WARIHRKRARAEKKRAQEERKLAQE-EEKLAQE-ERQLAQEERK-LAQA 1619
Query: 239 WLK----KKNAEECERKKKEKEKEKQQQAE--IQEKKEIAEKK---FQEWLENAKHKPRP 289
++K + + E K +KE+ Q+ E QE +++A+K+ ++W + A+ + +
Sbjct: 1620 YVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKL 1679
Query: 290 AAK 292
A K
Sbjct: 1680 AKK 1682
Score = 51.6 bits (122), Expect = 1e-06
Identities = 53/207 (25%), Positives = 91/207 (43%), Gaps = 34/207 (16%)
Query: 85 EDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPESRLTP 144
+DEE+V EE+V + + E +V E + QEE K R+ R
Sbjct: 1539 KDEEEVTLEEEVSREGEEKEQQVTE--------------EQRHIQEEHKWARIHRKRAR- 1583
Query: 145 WEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKR----KIIAEEKHKEWVQKKN 200
++K ++ +L EE Q E++ EER+ KI +++ + K
Sbjct: 1584 ------AEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKF 1637
Query: 201 EQKRK---EREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEECERK-----K 252
QK + +R +K+++E E+ A K + EK + +E L KK + E K K
Sbjct: 1638 AQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVARE-EEKLAKKGGKLAEVKNILAQK 1696
Query: 253 KEKEKEKQQQAEIQEKKEIAEKKFQEW 279
E+ +++Q + QEK+ E + EW
Sbjct: 1697 VEELPQREQNLDWQEKELAQELEELEW 1723
Score = 48.1 bits (113), Expect = 1e-05
Identities = 41/160 (25%), Positives = 81/160 (50%), Gaps = 10/160 (6%)
Query: 128 NQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREK---- 183
+QE +K + + WE + +E+E+ + K E N +K +E+ +RE+
Sbjct: 1652 SQEAEKLAQKRKKLAKKWEK--VAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDW 1709
Query: 184 --RKIIAEEKHKEWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWLK 241
+++ E + EW ++ K +E Q+ K +EEK E+E L + ++ +E +
Sbjct: 1710 QEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEE--E 1767
Query: 242 KKNAEECERKKKEKEKEKQQQAEIQEKKEIAEKKFQEWLE 281
K A+E E +EKEK Q + ++ E++E +K ++ +E
Sbjct: 1768 TKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIE 1807
Score = 47.0 bits (110), Expect = 3e-05
Identities = 56/255 (21%), Positives = 112/255 (43%), Gaps = 41/255 (16%)
Query: 69 PLGHQSFQFDEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGME-------------- 114
P+ Q ED G +E + +E + + ++ K + G+E
Sbjct: 1316 PIFIQEGAIREDMIQGVTQEVIRHKEVMPREEEQAQKKARDMLGLEETQVILKKGKKVIF 1375
Query: 115 LQGCASTQVESENNQEEQK--QVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQL 172
L+ T + + +EE+K Q + R + +GK K E + + EE+ +
Sbjct: 1376 LEPGNVTMGKEISKKEEKKTFQKSPKQGRKAVQKERKVGKIKREMTKEERDMSEEVEEMA 1435
Query: 173 EKRKEMEEREKRKIIAEEKHK---------EWVQKKNEQKR------KEREQKINKEMEE 217
+++ ++E + ++ E EW Q E ++ +E E+++ +E E+
Sbjct: 1436 TLEEKVVKQEGKLVMIERTPSWQDWKKAWDEWKQVHGETRKSWKAWKEEWEKRLLQEEEK 1495
Query: 218 --KAAKEL--EKEYLQEKAKEKYQEWLKKKNAEECERKKKEKEKEKQQQAEIQEKKEIA- 272
+A ++L E+E LQE K K++EW K E K KE++ + + E+ ++E++
Sbjct: 1496 LHQAGEKLSPEEEMLQEDKKLKWEEW---KQVWENMLSSKSKEQQYKDEEEVTLEEEVSR 1552
Query: 273 --EKKFQEWLENAKH 285
E+K Q+ E +H
Sbjct: 1553 EGEEKEQQVTEEQRH 1567
Score = 46.2 bits (108), Expect = 5e-05
Identities = 33/163 (20%), Positives = 83/163 (50%), Gaps = 22/163 (13%)
Query: 152 KEKEERDRLQLKALEELNQQLEKRKEMEEREKR------KIIAEEKH------------- 192
K++++ R Q K ++ + + K ++M E E + ++I +++
Sbjct: 2134 KDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFL 2193
Query: 193 -KEWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKE-KYQEWLKKKNAEECER 250
+ W ++K ++ + ++K + +++E ++E E ++ E + QE L + EE E
Sbjct: 2194 KRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREE 2253
Query: 251 KKKEKEKE-KQQQAEIQEKKEIAEKKFQEWLENAKHKPRPAAK 292
+++ +E+E ++++ E +E++E EK+ ++ E K K + K
Sbjct: 2254 EEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKK 2296
Score = 44.7 bits (104), Expect = 1e-04
Identities = 61/240 (25%), Positives = 111/240 (46%), Gaps = 49/240 (20%)
Query: 81 DGDGEDEEDVDDEEDVDED-----AHDSEAKVASLRGMELQGCASTQVESENNQEEQKQV 135
+G+ ++++ +++ + E+ H A+ R E + A E E +E++Q+
Sbjct: 1553 EGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQ---EEEKLAQEERQL 1609
Query: 136 RLPESRLTPWEVWFIGKEKE---------ERDRLQLKALEELNQQLEK----RKEMEERE 182
E +L V ++E +++ + E+L+Q+ EK RK++ ++
Sbjct: 1610 AQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKW 1669
Query: 183 KRKIIAEEKHKEWVQKKNEQKR---------KEREQKINKEMEEKAAKELEK-----EYL 228
++ EEK + K E K +REQ ++ + E++ A+ELE+ E L
Sbjct: 1670 EKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQ-EKELAQELEELEWDMEEL 1728
Query: 229 QEKAKEKYQEW-----LKKKNAEECE-----RKKKEKEKEKQQQAE---IQEKKEIAEKK 275
K +E QE KKK AEE E R+K +E+ K Q E IQEK+++A+ K
Sbjct: 1729 SWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHK 1788
Score = 44.7 bits (104), Expect = 1e-04
Identities = 52/214 (24%), Positives = 92/214 (42%), Gaps = 25/214 (11%)
Query: 60 SNSTRSLLSPLGHQSFQFDEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCA 119
S SLL L Q E++ + E+EE+ ++EE +E+ E E +G
Sbjct: 2227 SEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKE---------EEEG-E 2276
Query: 120 STQVESENNQEEQKQVRLPESRLTPWEVWFIGKE----KEERDRLQLKALEELNQQLEKR 175
QVE E ++++K+ + + E F KE +EE + L + EE + LE
Sbjct: 2277 EKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLE-- 2334
Query: 176 KEMEEREKRKIIAEEKHKEWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEK 235
E +REK + E++ K Q++ + +ER I + + + + L+
Sbjct: 2335 -EEVDREKEILKKEKQFKLQEQRRKSLRGRERVLSILRGVPHGKGRAIRLGVLKSP---- 2389
Query: 236 YQEWLKKKNAEECERKKKEKEKEKQQQAEIQEKK 269
LKK + E K+K ++Q ++KK
Sbjct: 2390 ----LKKLMSTALEMKEKTPVPVPEKQISWEDKK 2419
Score = 42.7 bits (99), Expect = 5e-04
Identities = 51/224 (22%), Positives = 105/224 (46%), Gaps = 29/224 (12%)
Query: 85 EDEEDVDDEEDV----DEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPES 140
E+++ + +EE+ E + E K+A + +Q E EE++++
Sbjct: 1744 EEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKRE 1803
Query: 141 RLTPWEVWFIGKEKEERDRLQLKALEELNQQ---LEKRKEMEEREKRKIIAEEKHKEWVQ 197
+L ++ K ++R+R + ++EEL + L ++K + + +K +A+EK K +
Sbjct: 1804 QLIEKKM----KLAQKRERW-INSMEELTKNKMILYQKKNLAQEKKN--LAQEKEKLAQR 1856
Query: 198 KKNEQKRKEREQKINKEMEE---------KAAKELEKEYLQEKA-----KEKYQEWLKKK 243
K+N KER K++ + K ++E++ QEK KEK E KK
Sbjct: 1857 KENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKEKLAETEKKL 1916
Query: 244 -NAEECERKKKEKEKEKQQQAEIQEKKEIAEKKFQEWLENAKHK 286
E+ KK+EK +++ + +++ +K+ + L+ AK +
Sbjct: 1917 VQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKEE 1960
Score = 39.7 bits (91), Expect = 0.004
Identities = 41/168 (24%), Positives = 80/168 (47%), Gaps = 13/168 (7%)
Query: 121 TQVESENNQEE---QKQVRLPESRLTPWEVWFIGKEKEERDRLQL------KALEELNQQ 171
TQVE E + + ++++ L E R+ E I K K E R Q + L + +++
Sbjct: 1999 TQVEQELFERKLSLEEKILLHEDRILAMEESEIAKGKLEFTRGQRIFVQGQRKLAKASRK 2058
Query: 172 LEKRKEMEEREKRKIIAEEKHKEWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEK 231
L K++E +E K+ K + +QK +RK +++I ++A E+ E+
Sbjct: 2059 LIKKRESLSKEPAKL---NKILKALQKLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQ 2115
Query: 232 AKEKYQEW-LKKKNAEECERKKKEKEKEKQQQAEIQEKKEIAEKKFQE 278
+K +EW +K +E + +KK K+++ +++ EK +E
Sbjct: 2116 SKLDIKEWDFSEKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEE 2163
Score = 38.1 bits (87), Expect = 0.013
Identities = 33/136 (24%), Positives = 70/136 (51%), Gaps = 13/136 (9%)
Query: 150 IGKEKEERDRLQLKALEELNQQLEKRKEMEEREKR-----KIIAEEKHKEWVQKKNEQKR 204
+ +EKE+ + + L + +K++ + + + KI+A+ + K +K+ K+
Sbjct: 1846 LAQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKK 1905
Query: 205 KEREQKINKEM---EEKAAKELEKEYLQEKAKEKYQEWLKKKNAEECERKKKEKEKEKQQ 261
KE+ + K++ E+ AK+ EK A+EK + L+K + +R + E + K++
Sbjct: 1906 KEKLAETEKKLVQVEDSLAKKQEK-----LAQEKMKLALEKAMVQGKKRLRGELDIAKEE 1960
Query: 262 QAEIQEKKEIAEKKFQ 277
+A E K +AE+K +
Sbjct: 1961 KALNLEMKRLAEEKMR 1976
Score = 38.1 bits (87), Expect = 0.013
Identities = 35/151 (23%), Positives = 77/151 (50%), Gaps = 14/151 (9%)
Query: 131 EQKQVRLPESRLTPWEVWFIGKEKE---ERDRLQLKALE--ELNQQLEKRKEMEEREKRK 185
+++++ E ++T + KE+ E+ +L +K + E +L K ++ R++RK
Sbjct: 2086 DERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDFSEKRSELTKDEKKLARKQRK 2145
Query: 186 IIAEEKHKEWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNA 245
+ K + + K E+K E E K+ ++ E + E+ ++E E+ +LK++
Sbjct: 2146 LA--NKMRRMINK--EEKMTEEESKLARKHSEVILDDEEEGGIEE---EEVIPFLKRRWR 2198
Query: 246 EECERKKKEKEKEK--QQQAEIQEKKEIAEK 274
+ E K+ +K KEK Q E++ ++ +E+
Sbjct: 2199 KRKEAKRGDKPKEKFSSQVDEVESEEHFSEE 2229
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 69.3 bits (168), Expect = 5e-12
Identities = 58/221 (26%), Positives = 113/221 (51%), Gaps = 14/221 (6%)
Query: 70 LGHQSFQFDEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQ 129
L Q ++++ E EE + D+E++ E K+ M Q + E +
Sbjct: 442 LWEQEKMQEQEEKIWEQEEKIRDQEEM----WGQEKKMWRQEKMREQEDQMWEQEEKMRD 497
Query: 130 EEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAE 189
+EQK E WE +EKEER R Q K ++ +++ + K+ +E+EK+ E
Sbjct: 498 QEQKMWDQEERM---WEQDERLREKEERMREQKKMWQQ-EEKMREEKKTQEQEKKTWDQE 553
Query: 190 EKHKEWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKA----KEKYQEWLKKKNA 245
EK +E + + +K+ E+++ +E EEK ++ EK QE+ +EK QE +K
Sbjct: 554 EKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWE 613
Query: 246 EECERKKKEKEKEKQQQAEI--QEKKEIAEKKFQEWLENAK 284
+E + ++E+E + Q+Q E+ ++++++ E++ + W + K
Sbjct: 614 QEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEK 654
Score = 68.2 bits (165), Expect = 1e-11
Identities = 50/192 (26%), Positives = 106/192 (55%), Gaps = 10/192 (5%)
Query: 97 DEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPESRLTPWEVWFIGKEKEE 156
+E+ + E K+ + + + +E+++++R E RL E +EKE
Sbjct: 240 EEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKEL 299
Query: 157 RDRLQLKALEE-LNQQLEKRKEMEE--REKRKIIAEEKHKEWVQKK----NEQKRKEREQ 209
R++ +L+ EE + +Q EK E EE RE+ + + ++ + W Q+K EQK +++E+
Sbjct: 300 REQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEE 359
Query: 210 KINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEECERKKKEKEKEKQQQAEIQEKK 269
++ E +E+ ++ E+ QEK E+ ++ +++ E E+K +E+E+ ++Q E +K+
Sbjct: 360 RM-WEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQ 418
Query: 270 E--IAEKKFQEW 279
E + E++ +EW
Sbjct: 419 EENMWEQEEKEW 430
Score = 67.8 bits (164), Expect = 2e-11
Identities = 60/228 (26%), Positives = 111/228 (48%), Gaps = 38/228 (16%)
Query: 85 EDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPESRLTP 144
E EE + +EE + E + ++R E + + E ++E +Q RLPE +
Sbjct: 383 EQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKL 442
Query: 145 WE----------VWFIGKEKEERDR-------------LQLKALEELNQQLEKRKEMEER 181
WE +W E+EE+ R Q K E+ +Q E+ ++M ++
Sbjct: 443 WEQEKMQEQEEKIW----EQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQ 498
Query: 182 EKRKIIAEEKHKEWVQKKNEQKRKEREQK-----INKEMEEKAAKELEKEYLQEKAKEKY 236
E++ EE+ E ++ E++ + REQK K EEK +E EK+ ++ K +
Sbjct: 499 EQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMRE 558
Query: 237 QEWLK---KKNAEECERKKKEKEKEKQQQAEIQEKKE---IAEKKFQE 278
+E ++ KK EE E ++++EK ++Q+ +++E++E E+K QE
Sbjct: 559 EERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQE 606
Score = 66.6 bits (161), Expect = 3e-11
Identities = 53/184 (28%), Positives = 96/184 (52%), Gaps = 20/184 (10%)
Query: 124 ESENNQEEQKQVRLPESRLTPWEVWFIG-----KEKEERDRLQLKALEELNQQL-EKRKE 177
+ E +E++K++R E ++ E +E+EE+ R Q K L E ++L E+ KE
Sbjct: 239 QEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKE 298
Query: 178 MEE----REKRKIIAEEKHKEWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAK 233
+ E RE+ + + E++ K W EQ+ K REQ+ +E+ E EK+ +++ K
Sbjct: 299 LREQKKLREQEEQMQEQEEKMW-----EQEEKMREQEEKMWRQEERLWEQEKQMREQEQK 353
Query: 234 EKYQE---WLKKKNAEECERKKKEKEKEKQQQAEIQEKKEI--AEKKFQEWLENAKHKPR 288
+ QE W + + E E + +E+EK +Q+ ++QE++ I EKK +E E + +
Sbjct: 354 MRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEE 413
Query: 289 PAAK 292
K
Sbjct: 414 KMQK 417
Score = 65.5 bits (158), Expect = 8e-11
Identities = 58/227 (25%), Positives = 109/227 (48%), Gaps = 31/227 (13%)
Query: 78 DEDDGDGEDEEDVDDEE-----------DVDEDAHDSEAKVASLRGMELQGCASTQVESE 126
+++D E EE + D+E + DE + E ++ + M Q E +
Sbjct: 483 EQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQ--EEKMREEK 540
Query: 127 NNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKI 186
QE++K+ E ++ +E+E + K EE E+ ++M+E+E++
Sbjct: 541 KTQEQEKKTWDQEEKM---------REEERMREREKKMREEEEMMREQEEKMQEQEEKMR 591
Query: 187 IAEEKHKEWVQKKNEQKRK--EREQKINKEMEEKAAKELEKEYLQEKAKEKYQE---WLK 241
EEK E +K EQ+ K E+E+K+ ++ EE +E E+ +++ K + QE W +
Sbjct: 592 EQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQ 651
Query: 242 KKNAEECERKKKEKEKEKQQQ----AEIQEKKEIAEKKFQEWLENAK 284
++ E E K +E+E++ Q Q E +EK + E+K +E E +
Sbjct: 652 EEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMR 698
Score = 64.3 bits (155), Expect = 2e-10
Identities = 53/211 (25%), Positives = 113/211 (53%), Gaps = 21/211 (9%)
Query: 85 EDEEDVDDEEDVDEDAH---DSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPESR 141
E +E + ++E + E + E K+ M Q + E QE+Q + + R
Sbjct: 437 EQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMR 496
Query: 142 LTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKR----KIIAEEKHKEWVQ 197
++W ++EER Q + L E +++ ++K+M ++E++ K E++ K W Q
Sbjct: 497 DQEQKMW----DQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQ 552
Query: 198 K---KNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQE-WLKKKNAEECERKKK 253
+ + E++ +ERE+K+ +E E +E + + +EK +E+ ++ W +++ +E E K
Sbjct: 553 EEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMW 612
Query: 254 EKEK---EKQQQAEIQEKKEI---AEKKFQE 278
E+E+ E++++ ++QE++E+ E+K QE
Sbjct: 613 EQEEKMWEQEEEDKMQEQEEMMWEQEEKMQE 643
Score = 62.0 bits (149), Expect = 8e-10
Identities = 43/164 (26%), Positives = 92/164 (56%), Gaps = 11/164 (6%)
Query: 124 ESENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREK 183
+ E +E+++++ E RL WE +E+E++ R Q + + E +++L +++E ++
Sbjct: 322 QEEKMREQEEKMWRQEERL--WEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQE 379
Query: 184 RKIIAEEKHKEWVQKKNEQKRKEREQKINKEMEEKAAK-------ELEKEYLQEKAKEKY 236
+ EEK +E + + +K+ E++ +E EEK K + EKE+ Q++ E+
Sbjct: 380 KMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQK 439
Query: 237 QEWLKKKNAEECERKKKEKEKEKQQQAEI--QEKKEIAEKKFQE 278
++ +++ +E E K E+E++ + Q E+ QEKK ++K +E
Sbjct: 440 EKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMRE 483
Score = 60.8 bits (146), Expect = 2e-09
Identities = 53/209 (25%), Positives = 110/209 (52%), Gaps = 31/209 (14%)
Query: 85 EDEEDVDDEED----VDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPES 140
E E+ + D+E+ DE + E ++ M E E +E++++R E
Sbjct: 349 EQEQKMRDQEERMWEQDERLREKEERMREQEKMW---------EQEEKMQEEERIREREK 399
Query: 141 RLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQKK- 199
++ +E+EE R Q + +++ + + +++E E +++R + E+K K W Q+K
Sbjct: 400 KM---------REEEETMREQEEKMQKQEENMWEQEEKEWQQQR--LPEQKEKLWEQEKM 448
Query: 200 --NEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKY-QEWLKKKNAEECERKKKEKE 256
E+K E+E+KI ++ EE +E +K + QEK +E+ Q W +++ + E+K ++E
Sbjct: 449 QEQEEKIWEQEEKI-RDQEEMWGQE-KKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQE 506
Query: 257 KEKQQQAE-IQEKKEIAEKKFQEWLENAK 284
+ +Q E ++EK+E ++ + W + K
Sbjct: 507 ERMWEQDERLREKEERMREQKKMWQQEEK 535
Score = 60.5 bits (145), Expect = 2e-09
Identities = 51/164 (31%), Positives = 91/164 (55%), Gaps = 16/164 (9%)
Query: 124 ESENNQEEQKQVRLPESRLTPWE--VWFIGKEKEERDRLQLKALEELNQQL-EKRKEMEE 180
E E EQK++R E ++ E +W E+EE+ R Q + + ++L E+ K+M E
Sbjct: 294 EQEKELREQKKLREQEEQMQEQEEKMW----EQEEKMREQEEKMWRQEERLWEQEKQMRE 349
Query: 181 REKRKIIAEEKHKEWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWL 240
+E++ EE+ E ++ E++ + REQ+ E EEK E+E ++E+ K+ +E
Sbjct: 350 QEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQ---EEERIREREKKMREEEE 406
Query: 241 KKKNAEECERKKKE-----KEKEKQQQAEIQEKKEIAE-KKFQE 278
+ EE +K++E +EKE QQQ ++K+++ E +K QE
Sbjct: 407 TMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQE 450
Score = 58.2 bits (139), Expect = 1e-08
Identities = 52/228 (22%), Positives = 110/228 (48%), Gaps = 20/228 (8%)
Query: 78 DEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRL 137
+E ++++ D EE + E+ E + E+ + + E QE+++++R
Sbjct: 538 EEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMM-----REQEEKMQEQEEKMRE 592
Query: 138 PESRLTPWEVWFIGKEKEERDRLQLKAL---EELNQQLEKRKEMEEREKRKIIAEEKHKE 194
E ++ WE +E+EE+ Q + + EE ++ E+ + M E+E++ EEK E
Sbjct: 593 QEEKM--WEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWE 650
Query: 195 WVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQE----------WLKKKN 244
+K EQ+ K REQ+ + +E+ +E E++ ++ K + QE W +++
Sbjct: 651 QEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEK 710
Query: 245 AEECERKKKEKEKEKQQQAEIQEKKEIAEKKFQEWLENAKHKPRPAAK 292
E K +E+ ++++ I+++KE +++ E E P +K
Sbjct: 711 MWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEERCSEPCLPPSK 758
Score = 57.8 bits (138), Expect = 2e-08
Identities = 47/167 (28%), Positives = 89/167 (53%), Gaps = 19/167 (11%)
Query: 126 ENNQEEQKQVRLPESRLTPWEVWFIGKE---KEERDRLQLKALEELNQQLEK-RKEMEER 181
+ N E Q+++RL ES + E+ KE K ER + L ++ Q E R+E E R
Sbjct: 187 KKNAELQEKLRLAESEKS--EIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELR 244
Query: 182 EKRKIIAEEKHKEWVQ---------KKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKA 232
E+ K I +++ K W Q K EQ+ K R Q+ +EK +E EKE ++K
Sbjct: 245 EQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKK 304
Query: 233 KEKYQEWLKKKNAEECERKKKEKEKE----KQQQAEIQEKKEIAEKK 275
+ +E ++++ + E+++K +E+E +Q++ +++K++ E++
Sbjct: 305 LREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQE 351
Score = 53.1 bits (126), Expect = 4e-07
Identities = 34/135 (25%), Positives = 80/135 (59%), Gaps = 7/135 (5%)
Query: 146 EVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQKKNEQKRK 205
E+W +E E+++ K E++ +Q E+ +E E + + + EEK + ++ EQ+++
Sbjct: 235 EMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQ---EEKMRRQEKRLREQEKE 291
Query: 206 EREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEECERKKKEK--EKEKQQQA 263
REQ+ KE+ E+ ++E +QE+ ++ +++ K + EE +++E+ E+EKQ +
Sbjct: 292 LREQE--KELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMRE 349
Query: 264 EIQEKKEIAEKKFQE 278
+ Q+ ++ E+ +++
Sbjct: 350 QEQKMRDQEERMWEQ 364
Score = 49.7 bits (117), Expect = 4e-06
Identities = 43/153 (28%), Positives = 83/153 (54%), Gaps = 25/153 (16%)
Query: 149 FIGKEKEERDRLQL---------KALEELNQQLEKRKEMEEREKRKI---IAEEKHK--- 193
+I + +ERD L L + L++ N +L+++ + E EK +I + E K K
Sbjct: 160 YIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLER 219
Query: 194 -----EWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEEC 248
VQ Q+ R+++ +E E+K K+ EK + QE+ + + QE ++ E+
Sbjct: 220 AKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEE-RLREQEGKMREQEEKM 278
Query: 249 ERKKK---EKEKE-KQQQAEIQEKKEIAEKKFQ 277
R++K E+EKE ++Q+ E++E+K++ E++ Q
Sbjct: 279 RRQEKRLREQEKELREQEKELREQKKLREQEEQ 311
Score = 29.3 bits (64), Expect = 6.0
Identities = 20/61 (32%), Positives = 31/61 (50%), Gaps = 2/61 (3%)
Query: 230 EKAKEKYQEWLKKKNAEECE--RKKKEKEKEKQQQAEIQEKKEIAEKKFQEWLENAKHKP 287
+KA +E K+++A E R E+ K++ AE+QEK +AE + E N K
Sbjct: 155 KKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELK 214
Query: 288 R 288
R
Sbjct: 215 R 215
>gi|22035602 mitogen-activated protein kinase kinase kinase kinase 4
isoform 1 [Homo sapiens]
Length = 1166
Score = 68.9 bits (167), Expect = 7e-12
Identities = 63/245 (25%), Positives = 121/245 (49%), Gaps = 30/245 (12%)
Query: 121 TQVESENNQEEQKQVRLPESRLTPWEVWFI-GKEKEERDRLQLKALEE------LNQQLE 173
T+ E ++EE+++V PE P + + G+ RD L+L+ + QQL
Sbjct: 319 TEYEYSGSEEEEEEV--PEQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQLL 376
Query: 174 KRKEMEERE--KRKIIAE-----EKHKEWVQKKNEQKRKEREQKINKEMEEKAAKELEKE 226
+ +++ E+E KR+++AE E+ KE ++ EQ+R+ERE + +E E++ ++ EK
Sbjct: 377 QEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKR 436
Query: 227 YLQEKAKEKYQEWLKKKNAEECERKKKEKEKEKQQQAEIQEKKEIAEKKF---QEWLENA 283
L+E + + +E +++ EE R ++E+E ++Q E Q E+ +++ Q L +
Sbjct: 437 RLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLLQEQAMLLHD 496
Query: 284 KHKPRPAAKSYGYANGKLTGFYSGNSYPEPAFYNPIPWKPIHMPPPKEAKDLSGRKSKR- 342
+P P +P+F+ P P H P A+++ R + R
Sbjct: 497 HRRPHPQHSQQPPP--------PQQERSKPSFHAPEP--KAHYEPADRAREVPVRTTSRS 546
Query: 343 PVISQ 347
PV+S+
Sbjct: 547 PVLSR 551
Score = 35.8 bits (81), Expect = 0.064
Identities = 36/145 (24%), Positives = 76/145 (52%), Gaps = 12/145 (8%)
Query: 149 FIGKEKEERD-RLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQKKNEQKRKER 207
FI + ER R+QLK + +++ +KR E +E E +EE+ +E +++ E
Sbjct: 288 FIRDQPNERQVRIQLK--DHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPS---- 341
Query: 208 EQKINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEECERKKKEKEKEKQQQAEIQE 267
+N E ++ + LQ++ KE+ E L+++ + E++ +E+E+ K+Q ++
Sbjct: 342 -SIVNVPGESTLRRDFLR--LQQENKER-SEALRRQQLLQ-EQQLREQEEYKRQLLAERQ 396
Query: 268 KKEIAEKKFQEWLENAKHKPRPAAK 292
K+ +K+ + LE + + R A +
Sbjct: 397 KRIEQQKEQRRRLEEQQRREREARR 421
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 68.6 bits (166), Expect = 9e-12
Identities = 45/169 (26%), Positives = 96/169 (56%), Gaps = 8/169 (4%)
Query: 124 ESENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEE--R 181
E E EQ+++R E + E ++++E++ + E++ +Q EK +E EE +
Sbjct: 348 ELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQ 407
Query: 182 EKRKIIAEEKHKEWVQ----KKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQ 237
E+ + + E++ K W Q ++ E+K + +E+KI +E E+K ++ EK QE+ ++ +
Sbjct: 408 EQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKI-REQEKKIREQEEKIREQEEMMQEQE 466
Query: 238 EWLKKKNAEECERKKKEKEKEKQQQAEIQEKKEIAEKKFQEWLENAKHK 286
E + ++ + CE++ K +E+E++ + + +EK EKK +E E + +
Sbjct: 467 EKMGEQEGKMCEQEAKMQEQEEKMRRQ-EEKIREQEKKIREQEEKIREQ 514
Score = 65.9 bits (159), Expect = 6e-11
Identities = 55/208 (26%), Positives = 110/208 (52%), Gaps = 20/208 (9%)
Query: 85 EDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQK---QVRLPESR 141
E EE + +E++ + E K+ L ++ + + E QEE+K Q + E
Sbjct: 327 EKEEKMRRQEEM---MWEKEEKIRELEE-KMHEQEKIREQEEKRQEEEKIREQEKRQEQE 382
Query: 142 LTPWEVWFIGKEKEERDRLQLKALEELNQQL--------EKRKEMEEREKRKIIAEEKHK 193
W +E+EE+ R Q + ++E +++ E+ +EM+E+E++ EEK +
Sbjct: 383 AKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIR 442
Query: 194 EWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAE---ECER 250
E +K EQ+ K REQ+ + +E+ E E + +++AK + QE ++ E E E+
Sbjct: 443 EQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEK 502
Query: 251 KKKEKEKEKQQQAEIQEKKEIAEKKFQE 278
K +E+E++ ++Q E+ +++E EK +++
Sbjct: 503 KIREQEEKIREQEEMMQEQE--EKMWEQ 528
Score = 65.5 bits (158), Expect = 8e-11
Identities = 45/195 (23%), Positives = 98/195 (50%), Gaps = 1/195 (0%)
Query: 85 EDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPESRLTP 144
E EE +EE + E E + R E ++ + ++++ ++ E
Sbjct: 361 EQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKM 420
Query: 145 WEVWFIGKEKEERDRLQLKALEELNQQLEKRKE-MEEREKRKIIAEEKHKEWVQKKNEQK 203
WE +E+EE+ R Q + + E +++ +++E + E+E+ EEK E K EQ+
Sbjct: 421 WEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQE 480
Query: 204 RKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEECERKKKEKEKEKQQQA 263
K +EQ+ +E+ +E EK+ +++ K + QE + ++ E+ ++++ +++++
Sbjct: 481 AKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQ 540
Query: 264 EIQEKKEIAEKKFQE 278
E +EK E+K +E
Sbjct: 541 EQEEKMRRQEEKMRE 555
Score = 64.7 bits (156), Expect = 1e-10
Identities = 52/174 (29%), Positives = 98/174 (56%), Gaps = 29/174 (16%)
Query: 122 QVESENNQEEQKQVRLPESRLTPWE--VWFIGKEKEERDRLQ----------LKALEE-- 167
Q E QE+++++R E ++ E +W EKEE+ R Q ++ LEE
Sbjct: 298 QEREEKIQEQEEKIREQEEKMRRQEEMMW----EKEEKMRRQEEMMWEKEEKIRELEEKM 353
Query: 168 -----LNQQLEKRKEMEEREKRKIIAEEKHKEWVQ--KKNEQKRKEREQ-KINKEMEEKA 219
+ +Q EKR+E E+ +++ E++ K W Q K EQ+ K REQ ++ +E EEK
Sbjct: 354 HEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKM 413
Query: 220 AKELEKEYLQEKAKEKYQEWLKKKNAEECERKKK---EKEKEKQQQAEIQEKKE 270
++ EK + QE+ ++ +E ++++ + E++KK ++EK ++Q+ +QE++E
Sbjct: 414 GEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEE 467
Score = 62.8 bits (151), Expect = 5e-10
Identities = 47/175 (26%), Positives = 98/175 (56%), Gaps = 21/175 (12%)
Query: 124 ESENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEM--EER 181
+ E QE +++++ E ++ +E+EE+ R Q + + E +++ +++EM E+
Sbjct: 293 QEEKIQEREEKIQEQEEKI---------REQEEKMRRQEEMMWEKEEKMRRQEEMMWEKE 343
Query: 182 EKRKIIAEEKHKEWVQKKNEQKRKE----REQKINKEMEEKAAKELEKEYLQEKAKEKYQ 237
EK + + E+ H++ ++ E+KR+E REQ+ +E E K ++ EK QE+ + +
Sbjct: 344 EKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQE 403
Query: 238 EWLKKKNAEECERKKK--EKEKEKQQQAE----IQEKKEIAEKKFQEWLENAKHK 286
E ++++ + E+++K E+E+E Q+Q E +EK EKK +E E + +
Sbjct: 404 EMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQ 458
Score = 62.4 bits (150), Expect = 6e-10
Identities = 56/222 (25%), Positives = 110/222 (49%), Gaps = 16/222 (7%)
Query: 73 QSFQFDEDDGDGEDEEDVDDEEDV--DEDAHDSEAKVASLRGMELQGCASTQVESENNQE 130
+ +++++ E EE + ++E + E+ E K+ + Q + E + ++
Sbjct: 336 EEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQ 395
Query: 131 EQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEE--REKRKIIA 188
E+K +R E + E ++ E++ + EE+ +Q EK + EE RE+ K I
Sbjct: 396 EEK-IREQEEMMQEQE-----EKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIR 449
Query: 189 EEKHKEWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEEC 248
E++ K Q++ Q+++E+ + +M E+ AK E+E + +EK +E ++K E
Sbjct: 450 EQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIRE--QEKKIREQ 507
Query: 249 ERKKKEKEKEKQQQA----EIQEKKEIAEKKFQEWLENAKHK 286
E K +E+E+ Q+Q E +EK E+K QE E + +
Sbjct: 508 EEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQ 549
Score = 61.6 bits (148), Expect = 1e-09
Identities = 57/222 (25%), Positives = 113/222 (50%), Gaps = 32/222 (14%)
Query: 72 HQSFQFDEDDGDGEDEEDVDDEED----------VDEDAHDSEAKVASLRGM-----ELQ 116
H+ + E + ++EE + ++E +E + E K+ M E
Sbjct: 354 HEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKM 413
Query: 117 GCASTQV--ESENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQL-- 172
G ++ + E QE+++++R E ++ E +E+EE+ R Q + ++E +++
Sbjct: 414 GEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKI--REQEEKIREQEEMMQEQEEKMGE 471
Query: 173 ------EKRKEMEEREKRKIIAEEKHKEWVQKKNEQKRKEREQ-KINKEMEEKAAKELEK 225
E+ +M+E+E++ EEK +E +K EQ+ K REQ ++ +E EEK ++ EK
Sbjct: 472 QEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEK 531
Query: 226 EYLQEKAKEKYQEWLKKKNAEECERKKKEKEKEKQQQAEIQE 267
QE EK QE +K +E E+ ++++ + +QQ+ ++QE
Sbjct: 532 MCEQE---EKMQEQEEKMRRQE-EKMREQEVRLRQQEEKMQE 569
Score = 58.2 bits (139), Expect = 1e-08
Identities = 53/190 (27%), Positives = 95/190 (50%), Gaps = 26/190 (13%)
Query: 112 GMELQGCAS---TQVESE------NNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQL 162
G ELQ ++ QVE N Q+E+K R E +E+EE+ + Q
Sbjct: 259 GKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKI----------QEREEKIQEQE 308
Query: 163 KALEELNQQLEKRKEME-EREKRKIIAEEKHKEWVQKKNEQKRKEREQKINKEMEEKAAK 221
+ + E +++ +++EM E+E++ EE E +K E + K EQ+ +E EE K
Sbjct: 309 EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEE---K 365
Query: 222 ELEKEYLQEKAKEKYQE---WLKKKNAEECERKKKEKEKEKQQQAEIQEKKEIAEKKFQE 278
E+E ++E+ K + QE W +++ E E K +E+E+ Q+Q E ++E + +E
Sbjct: 366 RQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEE 425
Query: 279 WLENAKHKPR 288
++ + K R
Sbjct: 426 EMQEQEEKMR 435
Score = 57.4 bits (137), Expect = 2e-08
Identities = 52/187 (27%), Positives = 96/187 (51%), Gaps = 22/187 (11%)
Query: 97 DEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPESRLTPWEVWFIGKEKEE 156
DE+ + AK+ +LQ S + E + N +E K+ L P + + + E
Sbjct: 204 DEELKEKNAKLQE----KLQLVESEKSEIQLNVKELKRKLERAKLLLPQQ-----QLQAE 254
Query: 157 RDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQKKNEQKRKEREQKIN---- 212
D L K L+ ++ +L+ + E E R + +++ K W Q E+K +ERE+KI
Sbjct: 255 ADHLG-KELQSVSAKLQAQVEENELWNR-LNQQQEEKMWRQ---EEKIQEREEKIQEQEE 309
Query: 213 --KEMEEKAAKELEKEYLQEKAKEKYQE--WLKKKNAEECERKKKEKEKEKQQQAEIQEK 268
+E EEK ++ E + +E+ + +E W K++ E E K E+EK ++Q+ + QE+
Sbjct: 310 KIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEE 369
Query: 269 KEIAEKK 275
++I E++
Sbjct: 370 EKIREQE 376
Score = 28.9 bits (63), Expect = 7.8
Identities = 24/78 (30%), Positives = 38/78 (48%), Gaps = 7/78 (8%)
Query: 218 KAAKELEKEY----LQEKAKEKYQEWLKKKN---AEECERKKKEKEKEKQQQAEIQEKKE 270
K A ELE+ Q+K ++Y E L K+ + E R E+ K++ A++QEK +
Sbjct: 160 KFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQ 219
Query: 271 IAEKKFQEWLENAKHKPR 288
+ E + E N K R
Sbjct: 220 LVESEKSEIQLNVKELKR 237
>gi|22758136 MAP7 domain containing 2 [Homo sapiens]
Length = 732
Score = 68.2 bits (165), Expect = 1e-11
Identities = 45/129 (34%), Positives = 76/129 (58%), Gaps = 14/129 (10%)
Query: 163 KALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQKKNEQKRKEREQKINKEMEEKAAKE 222
K L E +Q +KE EE+E+ EK ++ ++ E KRK E+++ +EE+A K+
Sbjct: 402 KILAEKRRQARLQKEQEEQER-----VEKEEQDRLEREELKRKAEEERLR--LEEEARKQ 454
Query: 223 LEKEYLQEKAKEKYQEWLKKKNAEECERK-------KKEKEKEKQQQAEIQEKKEIAEKK 275
E+ QE+ K+K + K+K EE +RK K+++E+EKQ++A I+++KE AE K
Sbjct: 455 EEERKRQEEEKKKQEGEEKRKAGEEAKRKAEEELLLKEKQEQEKQEKAMIEKQKEAAETK 514
Query: 276 FQEWLENAK 284
+E E +
Sbjct: 515 AREVAEQMR 523
Score = 67.8 bits (164), Expect = 2e-11
Identities = 76/268 (28%), Positives = 118/268 (44%), Gaps = 29/268 (10%)
Query: 27 RPSSDSCSVPMTGARGQGLEVVRSPSPPLPLSC---SNSTRSLLSPLGHQSFQFDEDDGD 83
RPSS S T A Q + + P P P+ + S + + + E +G
Sbjct: 287 RPSSPVISKTATKAYPQSPKTTKPPYPGSPVKYRLPALSGQDMPKRKAEKEKSNKEREGT 346
Query: 84 ------GEDEEDVDDEEDVDEDAHDSEAKVASLR-------GMELQGCASTQVESENNQE 130
G E+ ++ VD+ A + A A + G G ++ E
Sbjct: 347 LAQQAAGPQGEEALEKHVVDKHASEKHAAAAGGKAENSAALGKPTAGTTDAGEAAKILAE 406
Query: 131 EQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEE 190
+++Q RL + + V EKEE+DRL+ EEL ++ E+ + E E RK E
Sbjct: 407 KRRQARLQKEQEEQERV-----EKEEQDRLER---EELKRKAEEERLRLEEEARKQEEER 458
Query: 191 KHKEWVQKK--NEQKRKEREQKINKEMEEKAAKELEKEYLQEKAK-EKYQEWLKKKNAEE 247
K +E +KK E+KRK E+ K EE KE +++ QEKA EK +E + K E
Sbjct: 459 KRQEEEKKKQEGEEKRKAGEEAKRKAEEELLLKEKQEQEKQEKAMIEKQKEAAETKAREV 518
Query: 248 CERKKKEKEKEKQQ--QAEIQEKKEIAE 273
E+ + E+E+ Q Q ++ KK I E
Sbjct: 519 AEQMRLEREQIMLQIEQERLERKKRIDE 546
Score = 38.1 bits (87), Expect = 0.013
Identities = 30/102 (29%), Positives = 57/102 (55%), Gaps = 6/102 (5%)
Query: 153 EKEERDRLQLKALEELNQQLEKRKE-MEEREKRKIIAEEKHKEWVQKKNEQKRKEREQKI 211
+ +ER RL + EE + L R++ + E++KR + EK E +K E++R+ +QK
Sbjct: 50 KSDERQRLAKERREEREKCLAAREQQILEKQKRARLQYEKQMEERWRKLEEQRQREDQK- 108
Query: 212 NKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEECERKKK 253
+EEK ++L +E +E+ + + L++ ++ E KKK
Sbjct: 109 RAAVEEKRKQKLREE--EERLEAMMRRSLER--TQQLELKKK 146
Score = 38.1 bits (87), Expect = 0.013
Identities = 27/99 (27%), Positives = 51/99 (51%), Gaps = 7/99 (7%)
Query: 170 QQLEKRKEMEEREKRKIIAEEKHKEWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQ 229
Q+L K + EEREK E++ E ++ Q K+ E++ K E++ ++ ++ ++
Sbjct: 55 QRLAKERR-EEREKCLAAREQQILEKQKRARLQYEKQMEERWRKLEEQRQREDQKRAAVE 113
Query: 230 EKAKEKYQEWLKKKNAEECERKKKEKEKEKQQQAEIQEK 268
EK K+K +E EE + E+ QQ E+++K
Sbjct: 114 EKRKQKLRE------EEERLEAMMRRSLERTQQLELKKK 146
Score = 35.8 bits (81), Expect = 0.064
Identities = 20/84 (23%), Positives = 51/84 (60%), Gaps = 5/84 (5%)
Query: 198 KKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEECERKKKEKEK 257
K +E++R +E++ E EK E++ L+++ + + Q +K+ E + ++++++
Sbjct: 50 KSDERQRLAKERR---EEREKCLAAREQQILEKQKRARLQ--YEKQMEERWRKLEEQRQR 104
Query: 258 EKQQQAEIQEKKEIAEKKFQEWLE 281
E Q++A ++EK++ ++ +E LE
Sbjct: 105 EDQKRAAVEEKRKQKLREEEERLE 128
Score = 35.0 bits (79), Expect = 0.11
Identities = 30/111 (27%), Positives = 57/111 (51%), Gaps = 20/111 (18%)
Query: 111 RGME--LQGCASTQVESENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQL-KALEE 167
+GME L+ ++ E +E +K + E ++ EK++R RLQ K +EE
Sbjct: 43 QGMEGFLKSDERQRLAKERREEREKCLAAREQQIL---------EKQKRARLQYEKQMEE 93
Query: 168 LNQQLE--------KRKEMEEREKRKIIAEEKHKEWVQKKNEQKRKEREQK 210
++LE KR +EE+ K+K+ EE+ E + +++ ++ ++ E K
Sbjct: 94 RWRKLEEQRQREDQKRAAVEEKRKQKLREEEERLEAMMRRSLERTQQLELK 144
Score = 34.7 bits (78), Expect = 0.14
Identities = 28/104 (26%), Positives = 59/104 (56%), Gaps = 12/104 (11%)
Query: 182 EKRKIIAEEKHKEWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQE--KAKEKYQEW 239
++R+ +A+E+ +E E+ REQ+I E +++A + EK+ + K +E+ Q
Sbjct: 52 DERQRLAKERREE-----REKCLAAREQQI-LEKQKRARLQYEKQMEERWRKLEEQRQRE 105
Query: 240 LKKKNAEECERKKKEKEKEKQQQA----EIQEKKEIAEKKFQEW 279
+K+ A E +RK+K +E+E++ +A ++ +++ KK W
Sbjct: 106 DQKRAAVEEKRKQKLREEEERLEAMMRRSLERTQQLELKKKYSW 149
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 67.8 bits (164), Expect = 2e-11
Identities = 49/191 (25%), Positives = 107/191 (56%), Gaps = 20/191 (10%)
Query: 112 GMELQGCAS---TQVESEN-----NQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLK 163
G ELQ ++ QVE NQ++++++ E ++ WE +E+EE+ R Q +
Sbjct: 271 GKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKI--QEQEEKIREQEE 328
Query: 164 ALEELNQQLEKRKEMEEREKRKIIAEEK---HKEWVQKKNEQKRKEREQKINK------E 214
+ E +++ +++EM ++ K+ +E+ KE ++ E+ E+E+K+ + E
Sbjct: 329 KIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWE 388
Query: 215 MEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEECERKKKEKEKEKQQQAEIQEKKE-IAE 273
EEK + EK + QEK +E+ ++ +++ E E++++++ K +Q+ +I+E++E I E
Sbjct: 389 KEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIRE 448
Query: 274 KKFQEWLENAK 284
++ + W + K
Sbjct: 449 QEKKMWRQEEK 459
Score = 67.0 bits (162), Expect = 3e-11
Identities = 56/229 (24%), Positives = 117/229 (51%), Gaps = 39/229 (17%)
Query: 87 EEDVDDEEDV---DEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPESRLT 143
EE + ++E++ E H+ E K+ + + + E +E+++++ E ++
Sbjct: 482 EEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIR 541
Query: 144 PWE--------------VWFIGKEKEERDRL-----QLKALEE--------LNQQLEKRK 176
E +W K +E+ D++ +++ EE + +Q EKR+
Sbjct: 542 EQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQ 601
Query: 177 EMEER----EKRKIIAEEKHKEWVQKKNEQKRKEREQ-KINKEMEEKAAKELEKEYLQEK 231
E EE+ E++ EEK +E +K EQ+ K REQ ++ +E EEK ++ EK QE+
Sbjct: 602 EQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEE 661
Query: 232 AKEKYQE--WLKKKNAEECERKKKEKEKEKQQQAEIQEKKEIAEKKFQE 278
++ +E W +++ E E+K +E+E++ ++Q E+ +++E EK +++
Sbjct: 662 KMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQE--EKMWEQ 708
Score = 65.9 bits (159), Expect = 6e-11
Identities = 56/218 (25%), Positives = 112/218 (51%), Gaps = 15/218 (6%)
Query: 78 DEDDGDGEDEEDVDDEEDV----DEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQK 133
++++ E EE + ++E+ +E + E K+ M + + + E E+++
Sbjct: 318 EQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 377
Query: 134 QVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHK 193
++R E + WE +E EE+ Q E++ +Q EKR+E E+ +++ E++ K
Sbjct: 378 KMRRQEEMM--WEKEEKIRELEEKMHEQ----EKIREQEEKRQEEEKIREQEKRQEQEAK 431
Query: 194 EWVQ--KKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEECERK 251
W Q K EQ+ K REQ+ +E+ E EK +EK +E+ + W +++ E E
Sbjct: 432 MWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEI 491
Query: 252 KKEKEKEKQQQAEIQEKKEIA---EKKFQEWLENAKHK 286
++KEK +Q+ +I++++E E+K +E E + +
Sbjct: 492 WRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQ 529
Score = 65.9 bits (159), Expect = 6e-11
Identities = 51/215 (23%), Positives = 106/215 (49%), Gaps = 25/215 (11%)
Query: 72 HQSFQFDEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGME--LQGCASTQVESENNQ 129
H+ + E + ++EE + ++E E + +R E ++ E
Sbjct: 401 HEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKI 460
Query: 130 EEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAE 189
EQ+++R E R E+W R ++ EE+ +Q EK E EE+ I +
Sbjct: 461 HEQEKIREEEKRQEQEEMW--------RQEEKIHEQEEIWRQKEKMHEQEEK-----IRK 507
Query: 190 EKHKEWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEECE 249
++ K W Q E+K +E+E+KI +E EEK ++ +EK +E+ + W +++ E E
Sbjct: 508 QEEKVWRQ---EEKIREQEEKI-REQEEKMWRQ------EEKIREQEEMWREEEKMHEQE 557
Query: 250 RKKKEKEKEKQQQAEIQEKKEIAEKKFQEWLENAK 284
+ +E+++++Q+ +++++I E++ + W + K
Sbjct: 558 KIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEK 592
Score = 63.5 bits (153), Expect = 3e-10
Identities = 50/206 (24%), Positives = 106/206 (51%), Gaps = 12/206 (5%)
Query: 85 EDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPESRLTP 144
++E+ EE + E + + +R E + Q E QEE + + R
Sbjct: 298 QEEKMWRQEEKIQEWEEKIQEQEEKIREQEEK--IREQEEKMRRQEEMMWEKEEKMRRQE 355
Query: 145 WEVWFIGKEKEERDRLQLKALEELNQQLEKRKEM--EEREKRKIIAEEKHKEWVQKKNEQ 202
+W EKEE+ R Q + + E +++ +++EM E+ EK + + E+ H++ ++ E+
Sbjct: 356 EMMW----EKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEE 411
Query: 203 KRKE----REQKINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEECERKKKEKEKE 258
KR+E REQ+ +E E K ++ EK QE+ + ++ + ++ + E++K +E++
Sbjct: 412 KRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEK 471
Query: 259 KQQQAEIQEKKEIAEKKFQEWLENAK 284
+Q+Q E+ ++E ++ + W + K
Sbjct: 472 RQEQEEMWRQEEKIHEQEEIWRQKEK 497
Score = 61.2 bits (147), Expect = 1e-09
Identities = 50/164 (30%), Positives = 91/164 (55%), Gaps = 22/164 (13%)
Query: 124 ESENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEER-- 181
E E QE+++ R E E+W ++ E++ K E++ +Q EK +E EE+
Sbjct: 468 EEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIR 527
Query: 182 --EKRKIIAEEKHKE----WVQKK---------NEQKRKEREQKINKEMEEKAAKELEKE 226
E++ EEK +E W +++ E+KR+E+E K+ ++ EEK ++ EK
Sbjct: 528 EQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQ-EEKIREQEEKV 586
Query: 227 YLQEKAKEKYQEWLKKKNAEECERKKKEKEKEKQQQAEIQEKKE 270
+ QE EK +E +K+ +E E+ K++EK ++Q+ +IQE++E
Sbjct: 587 WRQE---EKIREQEEKRQEQE-EKMWKQEEKIREQEEKIQEQEE 626
Score = 60.8 bits (146), Expect = 2e-09
Identities = 41/161 (25%), Positives = 92/161 (57%), Gaps = 6/161 (3%)
Query: 124 ESENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEE--- 180
E E EQ+++R E + E ++++E++ + E++ +Q EK +E E+
Sbjct: 395 ELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMW 454
Query: 181 REKRKIIAEEKHKEWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWL 240
R++ KI +EK +E +++ +++ +E+KI+++ E KE E ++ K++ + W
Sbjct: 455 RQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWR 514
Query: 241 KKKNAEECERK-KKEKEKEKQQQAEIQEKKEI--AEKKFQE 278
+++ E E K ++++EK +Q+ +I+E++E+ E+K E
Sbjct: 515 QEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHE 555
Score = 59.7 bits (143), Expect = 4e-09
Identities = 53/215 (24%), Positives = 111/215 (51%), Gaps = 20/215 (9%)
Query: 78 DEDDGDGEDEEDVDDEEDV---DEDAHDSEAKVASLRGMELQGCASTQVESENNQEE--- 131
++++ EE + ++E++ +E H+ E + E + Q E QEE
Sbjct: 528 EQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVW 587
Query: 132 --QKQVRLPESRLTPWE--VWFIGKEKEERDRLQLKALEELNQQLEKRKE-MEEREKRKI 186
++++R E + E +W ++EE+ R Q + ++E +++ +++E + E+E+
Sbjct: 588 RQEEKIREQEEKRQEQEEKMW----KQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQ 643
Query: 187 IAEEKHKEWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAE 246
EEK E +K EQ+ K +EQ+ +E+ +E EK+ +++ K + QE + ++ E
Sbjct: 644 EQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEE 703
Query: 247 ---ECERKKKEKEKEKQQQAEIQEKKEIAEKKFQE 278
E E K E+E++ Q+Q E ++E EK +++
Sbjct: 704 KMWEQEEKMCEQEEKMQEQEEKMRRQE--EKMWEQ 736
Score = 58.5 bits (140), Expect = 9e-09
Identities = 53/191 (27%), Positives = 97/191 (50%), Gaps = 17/191 (8%)
Query: 97 DEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQ------VRLPESRLTPWEVWFI 150
DE+ + AK+ +LQ S + E + N +E K+ + LP+ +L E +
Sbjct: 216 DEELKEKNAKLQE----KLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQA-EADHL 270
Query: 151 GKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQKKNEQKRKEREQK 210
GKE + +L+A E N+ + + +E + + EEK +EW +K EQ+ K REQ+
Sbjct: 271 GKELQSVSA-KLQAQVEENELWNRLNQQQEEKMWR--QEEKIQEWEEKIQEQEEKIREQE 327
Query: 211 IN-KEMEEKAAKELEKEYLQEKAKEKYQE--WLKKKNAEECERKKKEKEKEKQQQAEIQE 267
+E EEK ++ E + +E+ + +E W K++ E EKE++ ++Q E+
Sbjct: 328 EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMW 387
Query: 268 KKEIAEKKFQE 278
+KE ++ +E
Sbjct: 388 EKEEKIRELEE 398
Score = 57.0 bits (136), Expect = 3e-08
Identities = 51/199 (25%), Positives = 102/199 (51%), Gaps = 16/199 (8%)
Query: 85 EDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQK---QVRLPESR 141
E EE + +E++ + E K+ L ++ + + E QEE+K Q + E
Sbjct: 374 EKEEKMRRQEEM---MWEKEEKIRELEE-KMHEQEKIREQEEKRQEEEKIREQEKRQEQE 429
Query: 142 LTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQKK-- 199
W +E+EE+ R Q K + +++ +++++ E EKR +E+ + W Q++
Sbjct: 430 AKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKR----QEQEEMWRQEEKI 485
Query: 200 NEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEECERKKKEKEKEK 259
+EQ+ R+++ E EEK K+ EK + QE EK +E +K +E + ++E++ +
Sbjct: 486 HEQEEIWRQKEKMHEQEEKIRKQEEKVWRQE---EKIREQEEKIREQEEKMWRQEEKIRE 542
Query: 260 QQQAEIQEKKEIAEKKFQE 278
Q++ +E+K ++K E
Sbjct: 543 QEEMWREEEKMHEQEKIWE 561
Score = 28.9 bits (63), Expect = 7.8
Identities = 24/78 (30%), Positives = 38/78 (48%), Gaps = 7/78 (8%)
Query: 218 KAAKELEKEY----LQEKAKEKYQEWLKKKN---AEECERKKKEKEKEKQQQAEIQEKKE 270
K A ELE+ Q+K ++Y E L K+ + E R E+ K++ A++QEK +
Sbjct: 172 KFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQ 231
Query: 271 IAEKKFQEWLENAKHKPR 288
+ E + E N K R
Sbjct: 232 LVESEKSEIQLNVKELKR 249
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 67.8 bits (164), Expect = 2e-11
Identities = 54/210 (25%), Positives = 115/210 (54%), Gaps = 13/210 (6%)
Query: 85 EDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPESRLTP 144
E EE + ++E E + E K+ M + + + E E+++++R E +
Sbjct: 318 EQEEKIREQE---EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWE 374
Query: 145 WEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIA---EEKHKEWVQKKNE 201
E E++ ++ +++ EE Q+ EK +E E+R++++ EEK +E +K E
Sbjct: 375 KEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIRE 434
Query: 202 QKRK--EREQKINKE---MEEKAAKELEKEYLQ-EKAKEKYQEWLKKKNAEECERKKKEK 255
Q++K +E+KI+++ EE+ +E E+ + Q EK +E+ + W +K+ E E+ +K++
Sbjct: 435 QEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQE 494
Query: 256 EKEKQQQAEIQEKKE-IAEKKFQEWLENAK 284
EK +Q+ ++ +++E I E++ + W + K
Sbjct: 495 EKVWRQEEKMHDQEEKIREQEEKMWRQEEK 524
Score = 67.8 bits (164), Expect = 2e-11
Identities = 57/220 (25%), Positives = 119/220 (54%), Gaps = 11/220 (5%)
Query: 73 QSFQFDEDDGDGEDEEDVDDEEDV--DEDAHDSEAKVASLRGMELQGCASTQVESENNQE 130
+ +++++ E EE + ++E + E+ E K+ + Q + E + ++
Sbjct: 369 EEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQ 428
Query: 131 EQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEE--REKRKIIA 188
E+K +R E ++ E I ++++ R+ + + EE+ +Q EK +E EE R+K K+
Sbjct: 429 EEK-IREQEKKMWRQEEK-IHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHE 486
Query: 189 EEKHKEWVQK--KNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAE 246
+EK ++ +K + E+K ++E+KI +E EEK ++ EK QE+ + +E K + E
Sbjct: 487 QEKIRKQEEKVWRQEEKMHDQEEKI-REQEEKMWRQEEKIREQEEKIREQEE--KIREQE 543
Query: 247 ECERKKKEKEKEKQQQAEIQEKKEIAEKKFQEWLENAKHK 286
E ++++EK E++++ + QEK E+K +E E + +
Sbjct: 544 EMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQ 583
Score = 67.4 bits (163), Expect = 2e-11
Identities = 60/234 (25%), Positives = 121/234 (51%), Gaps = 25/234 (10%)
Query: 72 HQSFQFDEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGME--LQGCASTQVESENNQ 129
H+ + E + ++EE + ++E E + +R E ++ E
Sbjct: 387 HEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKI 446
Query: 130 EEQKQVRLPESRLTPWEVWFIG---KEKEE--RDRLQLKALEELNQQLEK--RKEMEERE 182
EQ+++R E R E+W +E+EE R + ++ E++ +Q EK R+E + +
Sbjct: 447 HEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHD 506
Query: 183 KRKIIAEEKHKEWVQ----KKNEQKRKEREQKINK------EMEEKAAKELEKEYLQEKA 232
+ + I E++ K W Q ++ E+K +E+E+KI + E EEK ++ EK +QE+
Sbjct: 507 QEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEK--MQEQE 564
Query: 233 KEKYQEWLKKKNAEECERKKKEKEKEKQQQAEIQEKKEIAEKKFQEWLENAKHK 286
K + QE +K E+ E+ +++KEK ++Q+ +I E++E ++ +E ++ + K
Sbjct: 565 KMRRQE---EKIREQEEKIREQKEKIREQEEKIWEQEEKIREQ-EEMMQEQEEK 614
Score = 65.1 bits (157), Expect = 1e-10
Identities = 44/171 (25%), Positives = 98/171 (57%), Gaps = 12/171 (7%)
Query: 122 QVESENNQEEQKQVRLPESRLTPWE--VWFIGKEKEERDRLQLKALEELNQQLEKRKEM- 178
Q + E +E+++++R E ++ E +W EKEE+ R Q + + E +++ + +EM
Sbjct: 317 QEQEEKIREQEEKIREQEEKMRRQEEMMW----EKEEKMRRQEEMMWEKEEKMRRLEEMM 372
Query: 179 -EEREKRKIIAEEKHKEWVQKKNEQKRKE----REQKINKEMEEKAAKELEKEYLQEKAK 233
E+ EK + + E+ H++ ++ E+KR+E REQ+ +E E K ++ EK QE+
Sbjct: 373 WEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKI 432
Query: 234 EKYQEWLKKKNAEECERKKKEKEKEKQQQAEIQEKKEIAEKKFQEWLENAK 284
+ ++ + ++ + E++K +E+++Q+Q E+ ++E ++ + W + K
Sbjct: 433 REQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEK 483
Score = 64.7 bits (156), Expect = 1e-10
Identities = 52/189 (27%), Positives = 104/189 (55%), Gaps = 28/189 (14%)
Query: 112 GMELQGCAS---TQVESEN-----NQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLK 163
G ELQ ++ QVE NQ++++++ E ++ WE +E+EE+ R Q +
Sbjct: 271 GKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKI--QEQEEKIREQEE 328
Query: 164 ALEELNQQLEKRKEMEEREKRKIIAEEK---HKEWVQKKNEQKRKEREQKINKEMEEK-- 218
+ E +++ +++EM ++ K+ +E+ KE ++ E+ E+E+KI +E+EEK
Sbjct: 329 KIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKI-RELEEKMH 387
Query: 219 --------AAKELEKEYLQEKAKEKYQE---WLKKKNAEECERKKKEKEKEK-QQQAEIQ 266
K E+E ++E+ K + QE W +++ E E K +E+EK+ +Q+ +I
Sbjct: 388 EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIH 447
Query: 267 EKKEIAEKK 275
E+++I E++
Sbjct: 448 EQEKIREEE 456
Score = 63.2 bits (152), Expect = 4e-10
Identities = 56/206 (27%), Positives = 108/206 (52%), Gaps = 36/206 (17%)
Query: 85 EDEEDVDDEEDV---DEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPESR 141
E E+ EE V +E HD E K+ + E +++++R E +
Sbjct: 486 EQEKIRKQEEKVWRQEEKMHDQEEKIRE--------------QEEKMWRQEEKIREQEEK 531
Query: 142 LTPWEVWFIGKEKEERDRLQLKALEELNQQL-EKRKEMEEREKRKIIAEEKHKEWVQKKN 200
+ +E+EE+ R Q + ++E +++ E+ ++M+E+EK + EEK +E +K
Sbjct: 532 I---------REQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRR-QEEKIREQEEKIR 581
Query: 201 EQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEECERKKKEKEKEKQ 260
EQK K REQ+ +++ E+ K E+E + ++ +EK W +++ E E K +E+E++ +
Sbjct: 582 EQKEKIREQE--EKIWEQEEKIREQEEMMQEQEEKM--WEQEEKMCEQEEKMQEQEEKMR 637
Query: 261 QQAEIQEKKEI----AEKKFQEWLEN 282
+Q E ++E+ E+K QE E+
Sbjct: 638 RQEEKMWEQEVRLRQQEEKMQEHQEH 663
Score = 61.6 bits (148), Expect = 1e-09
Identities = 56/199 (28%), Positives = 104/199 (52%), Gaps = 25/199 (12%)
Query: 97 DEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQ------VRLPESRLTPWEVWFI 150
DE+ + AK+ +LQ S + E + N +E K+ + LP+ +L E +
Sbjct: 216 DEELKEKNAKLQE----KLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQA-EADHL 270
Query: 151 GKEKEERDRLQLKALEE------LNQQLEKR-----KEMEEREKRKIIAEEKHKEWVQKK 199
GKE + +EE LNQQ E++ ++++E E++ EEK +E +K
Sbjct: 271 GKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKI 330
Query: 200 NEQKRK-EREQKINKEMEEKAAKELEKEYLQEKAKEKYQE--WLKKKNAEECERKKKEKE 256
EQ+ K R++++ E EEK ++ E + +E+ + +E W K++ E E K E+E
Sbjct: 331 REQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQE 390
Query: 257 KEKQQQAEIQEKKEIAEKK 275
K ++Q+ + QE+++I E++
Sbjct: 391 KIREQEEKRQEEEKIREQE 409
Score = 61.2 bits (147), Expect = 1e-09
Identities = 58/228 (25%), Positives = 114/228 (50%), Gaps = 28/228 (12%)
Query: 73 QSFQFDEDDGDGEDEEDVDDEED----VDEDAHDSEAKVASLRGMELQGCASTQVESENN 128
+ +++++ EE + ++E+ ++E + E K+ L ++ + + E
Sbjct: 341 EEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEE-KMHEQEKIREQEEKR 399
Query: 129 QEEQK---QVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRK 185
QEE+K Q + E W +E+EE+ R Q K + +++ +++++ E EKR
Sbjct: 400 QEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKR- 458
Query: 186 IIAEEKHKEWVQKKN--------EQKRKEREQ-KINKEMEEKAAKELEKEYLQEKAKEKY 236
+E+ + W Q++ QK K EQ KI K+ EEK ++ EK + QE+ +
Sbjct: 459 ---QEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQ-EEKVWRQEEKMHDQEEKIREQ 514
Query: 237 QE--WLKKKNAEECERKKKEKEKEKQQQAEI----QEKKEIAEKKFQE 278
+E W +++ E E K +E+E++ ++Q E+ +EK E+K QE
Sbjct: 515 EEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQE 562
Score = 56.2 bits (134), Expect = 5e-08
Identities = 47/189 (24%), Positives = 96/189 (50%), Gaps = 29/189 (15%)
Query: 124 ESENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQL------KALEELNQQLEKRKE 177
E E QE+++ R E E+W ++ E+++++ + E+++ Q EK +E
Sbjct: 454 EEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIRE 513
Query: 178 MEE---------REKRKIIAEEKHK----EWVQKKNEQKRKEREQKINKE----MEEKAA 220
EE RE+ + I E++ K E + ++ E+K E+E+K+ ++ +E+
Sbjct: 514 QEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKI 573
Query: 221 KELEKEYLQEKAKEKYQE---WLKKKNAEECERKKKEKEKEKQQQAEIQEKKEIAEKKFQ 277
+E E++ ++K K + QE W +++ E E +E+E++ +Q +EK E+K Q
Sbjct: 574 REQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQ---EEKMCEQEEKMQ 630
Query: 278 EWLENAKHK 286
E E + +
Sbjct: 631 EQEEKMRRQ 639
Score = 55.1 bits (131), Expect = 1e-07
Identities = 47/210 (22%), Positives = 104/210 (49%), Gaps = 13/210 (6%)
Query: 72 HQSFQFDEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEE 131
H+ + E++ E EE EE + E K M Q Q E QEE
Sbjct: 447 HEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQK----EKMHEQEKIRKQEEKVWRQEE 502
Query: 132 QKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEK 191
+ + + R ++W +EE+ R Q + + E +++ +++EM + ++ K+ +E+
Sbjct: 503 KMHDQEEKIREQEEKMW----RQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEE 558
Query: 192 HKEWVQKKNEQKRKEREQKINKEMEEKAAK---ELEKEYLQEKAKEKYQEWLKKKNAEEC 248
+ +K Q+ K REQ+ +++ E+ K + EK + QE+ + +E ++++ +
Sbjct: 559 KMQEQEKMRRQEEKIREQE--EKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMW 616
Query: 249 ERKKKEKEKEKQQQAEIQEKKEIAEKKFQE 278
E+++K E+E++ Q + ++ + EK +++
Sbjct: 617 EQEEKMCEQEEKMQEQEEKMRRQEEKMWEQ 646
Score = 28.9 bits (63), Expect = 7.8
Identities = 24/78 (30%), Positives = 38/78 (48%), Gaps = 7/78 (8%)
Query: 218 KAAKELEKEY----LQEKAKEKYQEWLKKKN---AEECERKKKEKEKEKQQQAEIQEKKE 270
K A ELE+ Q+K ++Y E L K+ + E R E+ K++ A++QEK +
Sbjct: 172 KFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQ 231
Query: 271 IAEKKFQEWLENAKHKPR 288
+ E + E N K R
Sbjct: 232 LVESEKSEIQLNVKELKR 249
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 67.8 bits (164), Expect = 2e-11
Identities = 45/171 (26%), Positives = 99/171 (57%), Gaps = 12/171 (7%)
Query: 122 QVESENNQEEQKQVRLPESRLTPWE--VWFIGKEKEERDRLQLKALEELNQQLEKRKEM- 178
Q + E +E+++++R E ++ E +W EKEE+ R Q + + E +++ +++EM
Sbjct: 378 QEQEEKIREQEEKIREQEEKMRRQEEMMW----EKEEKMRRQEEMMWEKEEKMRRQEEMM 433
Query: 179 -EEREKRKIIAEEKHKEWVQKKNEQKRKE----REQKINKEMEEKAAKELEKEYLQEKAK 233
E+ EK + + E+ H++ ++ E+KR+E REQ+ +E E K ++ EK QE+
Sbjct: 434 WEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKI 493
Query: 234 EKYQEWLKKKNAEECERKKKEKEKEKQQQAEIQEKKEIAEKKFQEWLENAK 284
+ +E + ++ + E++K +E+++Q+Q E+ ++E ++ + W + K
Sbjct: 494 REQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEK 544
Score = 66.6 bits (161), Expect = 3e-11
Identities = 54/226 (23%), Positives = 120/226 (53%), Gaps = 14/226 (6%)
Query: 72 HQSFQFDEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGME--LQGCASTQVESENNQ 129
H+ + E + ++EE + ++E E + +R E ++ E
Sbjct: 448 HEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKI 507
Query: 130 EEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEER----EKRK 185
EQ+++R E R E+W ++ E++ + + E++++Q EK ++ EE+ E++
Sbjct: 508 HEQEKIREEEKRQEQEEMWRQEEKIREQEEIW-RQKEKIHEQEEKIRKQEEKMWRQEEKM 566
Query: 186 IIAEEKHKEWVQK--KNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWL--- 240
EEK +E +K + E+K +E+E+KI +E EEK ++ E QE+ + +E +
Sbjct: 567 HDQEEKIREQEEKVWRQEEKIREQEEKI-REQEEKIREQEEMTQEQEEKMGEQEEKMCEQ 625
Query: 241 KKKNAEECERKKKEKEKEKQQQAEIQEKKEIAEKKFQEWLENAKHK 286
++K E+ E+ ++++EK ++Q+ +I+E++E ++ +E ++ + K
Sbjct: 626 EEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQ-EEMMQEQEEK 670
Score = 66.2 bits (160), Expect = 4e-11
Identities = 56/192 (29%), Positives = 104/192 (54%), Gaps = 19/192 (9%)
Query: 85 EDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPESRLTP 144
E EE + ++E E + E K+ M + + + E E+++++R E +
Sbjct: 379 EQEEKIREQE---EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMM-- 433
Query: 145 WEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQKKNEQKR 204
WE +E EE+ Q E++ +Q EKR+E E+ +++ E++ K W + E+K
Sbjct: 434 WEKEEKIRELEEKMHEQ----EKIREQEEKRQEEEKIREQEKRQEQEAKMW---RQEEKI 486
Query: 205 KEREQKINKEMEEKAAKELEKEYLQEKAK--EKYQE----WLKKKNAEECERKKKEKEKE 258
+E+E+KI +E EEK ++ EK + QEK + EK QE W +++ E E ++KEK
Sbjct: 487 REQEEKI-REQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKI 545
Query: 259 KQQQAEIQEKKE 270
+Q+ +I++++E
Sbjct: 546 HEQEEKIRKQEE 557
Score = 66.2 bits (160), Expect = 4e-11
Identities = 52/167 (31%), Positives = 97/167 (58%), Gaps = 17/167 (10%)
Query: 124 ESENNQEEQKQVRLPESRLTPWEVWFIGK---EKEERDRLQLKAL----EELNQQLEKRK 176
E E QE+++ R E E+W + E+EE+ R Q + + E+++ Q EK +
Sbjct: 515 EEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIR 574
Query: 177 EMEEREKRKIIAEEKHKEWVQKKNEQKRKEREQK-INKEMEEKAAKELEKEYLQEKAKEK 235
E EE+ R+ EEK +E +K EQ+ K REQ+ + +E EEK ++ EK QE+ ++
Sbjct: 575 EQEEKVWRQ---EEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQE 631
Query: 236 YQEWLKKKNAEECERKKKEKEKEKQQQAE-IQEKKEIAEKKFQEWLE 281
+E ++++ E K +E+EK+ ++Q E I+E++E+ +++ ++ E
Sbjct: 632 QEEKMRRQ-----EEKIREQEKKIREQEEKIREQEEMMQEQEEKMWE 673
Score = 65.9 bits (159), Expect = 6e-11
Identities = 47/182 (25%), Positives = 105/182 (57%), Gaps = 16/182 (8%)
Query: 112 GMELQGCAS---TQVESEN-----NQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLK 163
G ELQ ++ QVE NQ++++++ E ++ WE +E+EE+ R Q +
Sbjct: 332 GKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKI--QEQEEKIREQEE 389
Query: 164 ALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQKKNEQKRKEREQKINKEMEEKAAKEL 223
+ E +++ +++EM ++ K+ + +E + +K E+ R R++++ E EEK +
Sbjct: 390 KIREQEEKMRRQEEMMWEKEEKM---RRQEEMMWEKEEKMR--RQEEMMWEKEEKIRELE 444
Query: 224 EKEYLQEKAKEKYQEWLKKKNAEECERKKKEKEKEKQQQAEIQEKKE-IAEKKFQEWLEN 282
EK + QEK +E+ ++ +++ E E++++++ K +Q+ +I+E++E I E++ + W +
Sbjct: 445 EKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQE 504
Query: 283 AK 284
K
Sbjct: 505 EK 506
Score = 65.5 bits (158), Expect = 8e-11
Identities = 52/204 (25%), Positives = 107/204 (52%), Gaps = 21/204 (10%)
Query: 87 EEDVDDEEDV---DEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPESRLT 143
EE + ++E++ E H+ E K+ + + E +E++++V E ++
Sbjct: 529 EEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKI- 587
Query: 144 PWEVWFIGKEKEERDRLQLKALEELNQQLEKRKE-MEEREKRKIIAEEKHKEWVQKKNEQ 202
+E+EE+ R Q + + E + ++++E M E+E++ EEK +E +K Q
Sbjct: 588 --------REQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQ 639
Query: 203 KRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEECERKKKEKEKEKQQQ 262
+ K REQ+ K++ E+ K E+E + ++ +EK W +++ E E K +E+E++ ++Q
Sbjct: 640 EEKIREQE--KKIREQEEKIREQEEMMQEQEEKM--WEQEEKMCEQEEKMQEQEEKMRRQ 695
Query: 263 AEIQEKKEI----AEKKFQEWLEN 282
E ++E+ E+K QE E+
Sbjct: 696 EEKMWEQEVRLRQQEEKMQEHQEH 719
Score = 62.4 bits (150), Expect = 6e-10
Identities = 41/170 (24%), Positives = 95/170 (55%), Gaps = 18/170 (10%)
Query: 124 ESENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEE--- 180
E E EQ+++R E + E ++++E++ + E++ +Q EK +E EE
Sbjct: 442 ELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMW 501
Query: 181 REKRKIIAEEKHKEWVQKKNEQKRKEREQKINK------------EMEEKAAKELEKEYL 228
R++ KI +EK +E +++ +++ +E+KI + E EEK K+ EK +
Sbjct: 502 RQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWR 561
Query: 229 QEKAKEKYQEWLKKKNAE---ECERKKKEKEKEKQQQAEIQEKKEIAEKK 275
QE+ +E ++++ + + E+ ++++EK ++Q+ +I+E++E+ +++
Sbjct: 562 QEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQ 611
Score = 62.4 bits (150), Expect = 6e-10
Identities = 49/210 (23%), Positives = 111/210 (52%), Gaps = 11/210 (5%)
Query: 78 DEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRL 137
++++ EE + ++E + E+ E + + +++ + E E+++++R
Sbjct: 495 EQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRK 554
Query: 138 PESRLTPWEVWFIGKEKEERDRLQL--KALEELNQQLEKRKEMEE--REKRKIIAEEKHK 193
E ++ E +E++ R++ + + E++ +Q EK +E EE RE+ ++ E++ K
Sbjct: 555 QEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEK 614
Query: 194 --EWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAE---EC 248
E +K EQ+ K +EQ+ +E+ +E EK+ +++ K + QE + ++ E E
Sbjct: 615 MGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQ 674
Query: 249 ERKKKEKEKEKQQQAEIQEKKEIAEKKFQE 278
E K E+E++ Q+Q E ++E EK +++
Sbjct: 675 EEKMCEQEEKMQEQEEKMRRQE--EKMWEQ 702
Score = 61.6 bits (148), Expect = 1e-09
Identities = 56/199 (28%), Positives = 104/199 (52%), Gaps = 25/199 (12%)
Query: 97 DEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQ------VRLPESRLTPWEVWFI 150
DE+ + AK+ +LQ S + E + N +E K+ + LP+ +L E +
Sbjct: 277 DEELKEKNAKLQE----KLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQA-EADHL 331
Query: 151 GKEKEERDRLQLKALEE------LNQQLEKR-----KEMEEREKRKIIAEEKHKEWVQKK 199
GKE + +EE LNQQ E++ ++++E E++ EEK +E +K
Sbjct: 332 GKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKI 391
Query: 200 NEQKRK-EREQKINKEMEEKAAKELEKEYLQEKAKEKYQE--WLKKKNAEECERKKKEKE 256
EQ+ K R++++ E EEK ++ E + +E+ + +E W K++ E E K E+E
Sbjct: 392 REQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQE 451
Query: 257 KEKQQQAEIQEKKEIAEKK 275
K ++Q+ + QE+++I E++
Sbjct: 452 KIREQEEKRQEEEKIREQE 470
Score = 54.3 bits (129), Expect = 2e-07
Identities = 50/219 (22%), Positives = 113/219 (51%), Gaps = 14/219 (6%)
Query: 73 QSFQFDEDDGDGEDEEDVDDEEDV--DEDAHDSEAKVASLRGMELQGCASTQVESENNQE 130
+ +++++ E EE + ++E + E+ E K+ + Q + E + ++
Sbjct: 430 EEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQ 489
Query: 131 EQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEE 190
E+K +R E ++ E I ++++ R+ + + EE+ +Q EK +E EE I +
Sbjct: 490 EEK-IREQEEKMWRQEEK-IHEQEKIREEEKRQEQEEMWRQEEKIREQEE------IWRQ 541
Query: 191 KHKEWVQKKNEQKRKE---REQKINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEE 247
K K Q++ +K++E R+++ + EEK ++ EK + QE+ + +E ++++ +
Sbjct: 542 KEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKI 601
Query: 248 CERKKKEKEKEKQQQAEIQEKKEIAEKKFQEWLENAKHK 286
E+++ +E+E ++ E +EK E+K QE E + +
Sbjct: 602 REQEEMTQEQE-EKMGEQEEKMCEQEEKMQEQEEKMRRQ 639
Score = 28.9 bits (63), Expect = 7.8
Identities = 24/78 (30%), Positives = 38/78 (48%), Gaps = 7/78 (8%)
Query: 218 KAAKELEKEY----LQEKAKEKYQEWLKKKN---AEECERKKKEKEKEKQQQAEIQEKKE 270
K A ELE+ Q+K ++Y E L K+ + E R E+ K++ A++QEK +
Sbjct: 233 KFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQ 292
Query: 271 IAEKKFQEWLENAKHKPR 288
+ E + E N K R
Sbjct: 293 LVESEKSEIQLNVKELKR 310
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 67.8 bits (164), Expect = 2e-11
Identities = 40/117 (34%), Positives = 77/117 (65%), Gaps = 7/117 (5%)
Query: 152 KEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQKKNEQKRKEREQKI 211
+E EE + + K + ++ EKRKE E+++K K EK KE K+ E+K+++R++K
Sbjct: 14 EETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTK--ETEKRKE---KEEEEKKRKRKRKK 68
Query: 212 NKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEECERKKKEKEKEKQQQAEIQEK 268
KE EE+ +E E+E +EK +E+ +E ++K ++ RK++E+EK+K+++ + ++K
Sbjct: 69 KKEEEEREEEEEEEE--EEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123
Score = 66.2 bits (160), Expect = 4e-11
Identities = 44/122 (36%), Positives = 76/122 (62%), Gaps = 7/122 (5%)
Query: 173 EKRKEMEEREKRKIIAEEKHKEWVQK-KNEQKRKEREQKIN-KEMEEKAAKELEKEYLQE 230
+K+KE EE E+ + EE+ KE +K K ++KRKE+E+K KE E++ KE E++ +
Sbjct: 5 KKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKR 64
Query: 231 KAKEKYQEWLKKKNAEECERKKKEKEKEKQQQAEIQEKKEIAEKKFQEWLENAKHKPRPA 290
K K+K +E ++ EE E +++EKE+E++++ ++KK+ +K +E E K K R
Sbjct: 65 KRKKKKEE---EEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEE--EEKKKKRRRK 119
Query: 291 AK 292
K
Sbjct: 120 TK 121
Score = 65.1 bits (157), Expect = 1e-10
Identities = 40/124 (32%), Positives = 77/124 (62%), Gaps = 4/124 (3%)
Query: 152 KEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQKKNEQKRKEREQKI 211
K+K++++ + + EE + E+ KE + +EKRK +EK K+ K+ E KRKE+E++
Sbjct: 3 KKKKKKETEETEETEETEE--EEEKEGKRKEKRKEKRKEKEKKKKTKETE-KRKEKEEE- 58
Query: 212 NKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEECERKKKEKEKEKQQQAEIQEKKEI 271
K+ + K K+ E+E +E+ +E+ +E +++ E RKKK+K + K+++ E ++K+
Sbjct: 59 EKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRR 118
Query: 272 AEKK 275
KK
Sbjct: 119 KTKK 122
Score = 61.6 bits (148), Expect = 1e-09
Identities = 33/119 (27%), Positives = 72/119 (60%)
Query: 156 ERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQKKNEQKRKEREQKINKEM 215
++ + + K EE + E +E E+ KRK +EK KE +KK ++ ++R++K +E
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60
Query: 216 EEKAAKELEKEYLQEKAKEKYQEWLKKKNAEECERKKKEKEKEKQQQAEIQEKKEIAEK 274
+ K ++ +KE + + +E+ +E K++ +E R++K+K+K ++++ E ++KK+ K
Sbjct: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRK 119
Score = 56.2 bits (134), Expect = 5e-08
Identities = 30/81 (37%), Positives = 56/81 (69%), Gaps = 2/81 (2%)
Query: 198 KKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEECERKKKEKEK 257
KK ++K+KE E+ +E EE +E ++ +EK KEK +E KKK +E E++K+++E+
Sbjct: 1 KKKKKKKKETEE--TEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEE 58
Query: 258 EKQQQAEIQEKKEIAEKKFQE 278
EK+++ + ++KKE E++ +E
Sbjct: 59 EKKRKRKRKKKKEEEEREEEE 79
Score = 55.5 bits (132), Expect = 8e-08
Identities = 39/142 (27%), Positives = 73/142 (51%), Gaps = 32/142 (22%)
Query: 121 TQVESENNQEEQKQVRLPESRLTPWEVWFIGKEKEER-DRLQLKALEELNQQLEKRKEME 179
T+ E +EE+K+ GK KE+R ++ + K ++ ++ EKRKE E
Sbjct: 13 TEETEETEEEEEKE----------------GKRKEKRKEKRKEKEKKKKTKETEKRKEKE 56
Query: 180 EREKRKIIAEEKHKEWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEW 239
E EK++ +K KE +++ E++ +E E+K +E EE ++ +K+
Sbjct: 57 EEEKKRKRKRKKKKE-EEEREEEEEEEEEEKEEEEKEEGRRRKKKKK------------- 102
Query: 240 LKKKNAEECERKKKEKEKEKQQ 261
+++ EE E+KKK + K K++
Sbjct: 103 -RRRKEEEEEKKKKRRRKTKKK 123
Score = 51.6 bits (122), Expect = 1e-06
Identities = 29/100 (29%), Positives = 60/100 (60%)
Query: 193 KEWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEECERKK 252
K+ +KK ++ +E E+ +E +E KE KE +EK K+K + +K+ +E E KK
Sbjct: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61
Query: 253 KEKEKEKQQQAEIQEKKEIAEKKFQEWLENAKHKPRPAAK 292
++++++K+++ E +E++E E++ +E E + + R K
Sbjct: 62 RKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKK 101
Score = 39.7 bits (91), Expect = 0.004
Identities = 22/69 (31%), Positives = 41/69 (59%)
Query: 224 EKEYLQEKAKEKYQEWLKKKNAEECERKKKEKEKEKQQQAEIQEKKEIAEKKFQEWLENA 283
+K+ ++K E+ +E + + EE E K+KEK KEK+++ E ++K + EK+ ++ E
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60
Query: 284 KHKPRPAAK 292
K K + K
Sbjct: 61 KRKRKRKKK 69
Score = 30.8 bits (68), Expect = 2.1
Identities = 28/122 (22%), Positives = 59/122 (48%), Gaps = 13/122 (10%)
Query: 85 EDEEDVDDEEDVDEDAHDSEAKVASLRGMELQG-CASTQVESENNQEEQKQVRLPESRLT 143
E EE + EE+ +++ E + + E + T+ E +EE+K+ R + +
Sbjct: 12 ETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKE 71
Query: 144 PWEVWFIGKEKEERDRLQLKALEELNQ--QLEKRKEMEEREKRKIIAEEKHKEWVQKKNE 201
E +E+EE + + K EE + + +K+K+ +E+ EE+ K+ ++K +
Sbjct: 72 EEE-----REEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEE-----EEEKKKKRRRKTK 121
Query: 202 QK 203
+K
Sbjct: 122 KK 123
>gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo
sapiens]
Length = 956
Score = 67.8 bits (164), Expect = 2e-11
Identities = 53/157 (33%), Positives = 90/157 (57%), Gaps = 16/157 (10%)
Query: 152 KEKEERDRLQLKALEE-LNQQLEKRKEMEEREKRKIIAEEKHKEWVQKKNEQKR---KER 207
K E+++L+L+ +E L +QL+ R E EE+EK K A+ +E +KK E+K KER
Sbjct: 327 KGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKER 386
Query: 208 EQKINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEECERKKKEKEKEKQQQAEIQE 267
+K K+ +EKA EK+ L+E+ +++ QE L+ K E +RKK+E+++ ++++ I+
Sbjct: 387 REKREKDEKEKA----EKQRLKEERRKERQEALEAKLEE--KRKKEEEKRLREEEKRIKA 440
Query: 268 KKEIAEKKFQEWLENAKHKPRPAAKSYGYANGKLTGF 304
+K + FQ K K A K+ + GK F
Sbjct: 441 EKAEITRFFQ------KPKTPQAPKTLAGSCGKFAPF 471
Score = 51.6 bits (122), Expect = 1e-06
Identities = 33/101 (32%), Positives = 60/101 (59%), Gaps = 4/101 (3%)
Query: 181 REKRKIIAEEKHKEWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWL 240
R +K + K ++ + +Q+R ++ K+ E EEK + E + +E+AK+K +E
Sbjct: 320 RITKKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEE-- 377
Query: 241 KKKNAEECERKKKEKEKEKQQQAEIQEKKEIAEKKFQEWLE 281
+K +E ER++K +EK+++++AE Q KE K+ QE LE
Sbjct: 378 -EKELKEKERREK-REKDEKEKAEKQRLKEERRKERQEALE 416
Score = 47.0 bits (110), Expect = 3e-05
Identities = 33/116 (28%), Positives = 56/116 (48%), Gaps = 30/116 (25%)
Query: 124 ESENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREK 183
E E +EE K +A EE ++ E+ KE++E+E+
Sbjct: 356 EKEKLKEEAK-----------------------------RAKEEAKKKKEEEKELKEKER 386
Query: 184 R-KIIAEEKHKEWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQE 238
R K +EK K Q+ E++RKER++ + ++EEK KE EK +E+ + K ++
Sbjct: 387 REKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEK 442
Score = 45.1 bits (105), Expect = 1e-04
Identities = 32/113 (28%), Positives = 66/113 (58%), Gaps = 9/113 (7%)
Query: 170 QQLEKRKEMEEREKRKIIAEEKHKEWVQKKNEQKRKEREQKINKEM-----EEKAAKELE 224
+++ K+ EK K+ + + ++ + +E ++K+ +E E K KE E
Sbjct: 319 RRITKKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEE 378
Query: 225 KEYLQEKAKEKYQEWLKKKNAEECERKKKEKEKEKQQ--QAEIQEKKEIAEKK 275
KE L+EK + + +E +K+ AE+ +R K+E+ KE+Q+ +A+++EK++ E+K
Sbjct: 379 KE-LKEKERREKREKDEKEKAEK-QRLKEERRKERQEALEAKLEEKRKKEEEK 429
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 67.8 bits (164), Expect = 2e-11
Identities = 54/207 (26%), Positives = 107/207 (51%), Gaps = 33/207 (15%)
Query: 82 GDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPESR 141
G ++ V DE+++ + ++++++ ++ + E E EEQ++ E
Sbjct: 430 GPFPSKQQVADEDEIWKQRRRQQSEISAA----VERARKRREEEERRMEEQRKAACAE-- 483
Query: 142 LTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQKKNE 201
+LK L+E LEK+ EE +R+ E + ++ ++K+ E
Sbjct: 484 -------------------KLKRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQE 524
Query: 202 QKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEECERKKKEKEKEKQQ 261
Q+R E+E++ ++E +++ KELEKE +EK +E K++ E+ + +++KEKEK+
Sbjct: 525 QER-EKEREKDRERQQEKEKELEKE------QEKQREMEKERKQEKEKELERQKEKEKEL 577
Query: 262 QAEIQEKKEIAEKKFQEWLENAKHKPR 288
Q +++KE +K +E LE K +PR
Sbjct: 578 QKMKEQEKECELEKEREKLEE-KIEPR 603
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 67.4 bits (163), Expect = 2e-11
Identities = 35/122 (28%), Positives = 76/122 (62%), Gaps = 1/122 (0%)
Query: 153 EKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQKKNEQKRKEREQKIN 212
+K + R + K+ + + +KRK+ E+ K K +EK +E +++ +++ KE+E+ N
Sbjct: 356 KKRSKSRERRKSRSRSHSR-DKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKN 414
Query: 213 KEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEECERKKKEKEKEKQQQAEIQEKKEIA 272
K+ +++ K+ EK+ +++ +E+ +E K ++ E+ + + KEKE+EK + EI EK++
Sbjct: 415 KDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKD 474
Query: 273 EK 274
+K
Sbjct: 475 KK 476
Score = 67.0 bits (162), Expect = 3e-11
Identities = 55/218 (25%), Positives = 104/218 (47%), Gaps = 9/218 (4%)
Query: 152 KEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEE-KHKEWVQKKNEQKRKEREQK 210
++ R + K + ++ + R R+KRK E+ K KE V++K+ +K +ERE++
Sbjct: 345 QKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKE 404
Query: 211 INKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEECERKKKEKEKEKQQQAEIQEK-- 268
KE E K+ +KE +EK +EK +E +++ E+ K ++KEKEK+Q E + +
Sbjct: 405 REKEKERGKNKDRDKE--REKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKD 462
Query: 269 --KEIAEKKFQEWLENAKHKPRPAAKSYGYANGKLTGFYSGNSYPEPAFYNPIPWKPIHM 326
KEI EK+ ++ + A++ ++ + S +S P I K
Sbjct: 463 RSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRS 522
Query: 327 PPP--KEAKDLSGRKSKRPVISQPHKSSSLVIHKARSN 362
P P + KD K + + + + S + K+ ++
Sbjct: 523 PSPRSRNKKDKKREKERDHISERRERERSTSMRKSSND 560
Score = 61.2 bits (147), Expect = 1e-09
Identities = 53/203 (26%), Positives = 93/203 (45%), Gaps = 7/203 (3%)
Query: 95 DVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPESRLTPWEVWFIGKEK 154
++ A E + R E Q S +E E+ + +++ S T + K
Sbjct: 265 EMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSH-TRSKSRSSSKSH 323
Query: 155 EERDRLQLKALEELNQQLEKRKEMEEREK----RKIIAEEKHKEWVQKKNEQKRKEREQK 210
R R Q K + + R++ R K ++ + E+ K + + KRK+ +K
Sbjct: 324 SRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREK 383
Query: 211 INKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEECERKKKEKEKEKQQQAEIQEKKE 270
I KE E K+ EKE +EK +EK +E K K+ ++ K +EK+KEK ++ E +EK+
Sbjct: 384 I-KEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRERE-REKEH 441
Query: 271 IAEKKFQEWLENAKHKPRPAAKS 293
++ ++ E K K R +S
Sbjct: 442 EKDRDKEKEKEQDKEKEREKDRS 464
Score = 37.7 bits (86), Expect = 0.017
Identities = 38/201 (18%), Positives = 74/201 (36%), Gaps = 37/201 (18%)
Query: 83 DGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPESRL 142
D + E + D E+D ++D R E + E E Q+++K+ S+
Sbjct: 416 DRDKEREKDREKDKEKDRE---------REREKEHEKDRDKEKEKEQDKEKEREKDRSK- 465
Query: 143 TPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQ----- 197
E+ EK ++D+ N R ER +R+ + + +
Sbjct: 466 ---EI----DEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRK 518
Query: 198 ----------KKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEE 247
K ++KR++ I++ E + + + K KEK + KN+
Sbjct: 519 SSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLE-----KNSTS 573
Query: 248 CERKKKEKEKEKQQQAEIQEK 268
+ K+ KE + E+ +K
Sbjct: 574 LKEKEHNKEPDSSVSKEVDDK 594
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 67.4 bits (163), Expect = 2e-11
Identities = 35/122 (28%), Positives = 76/122 (62%), Gaps = 1/122 (0%)
Query: 153 EKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQKKNEQKRKEREQKIN 212
+K + R + K+ + + +KRK+ E+ K K +EK +E +++ +++ KE+E+ N
Sbjct: 240 KKRSKSRERRKSRSRSHSR-DKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKN 298
Query: 213 KEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEECERKKKEKEKEKQQQAEIQEKKEIA 272
K+ +++ K+ EK+ +++ +E+ +E K ++ E+ + + KEKE+EK + EI EK++
Sbjct: 299 KDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKD 358
Query: 273 EK 274
+K
Sbjct: 359 KK 360
Score = 67.0 bits (162), Expect = 3e-11
Identities = 55/218 (25%), Positives = 104/218 (47%), Gaps = 9/218 (4%)
Query: 152 KEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEE-KHKEWVQKKNEQKRKEREQK 210
++ R + K + ++ + R R+KRK E+ K KE V++K+ +K +ERE++
Sbjct: 229 QKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKE 288
Query: 211 INKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEECERKKKEKEKEKQQQAEIQEK-- 268
KE E K+ +KE +EK +EK +E +++ E+ K ++KEKEK+Q E + +
Sbjct: 289 REKEKERGKNKDRDKE--REKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKD 346
Query: 269 --KEIAEKKFQEWLENAKHKPRPAAKSYGYANGKLTGFYSGNSYPEPAFYNPIPWKPIHM 326
KEI EK+ ++ + A++ ++ + S +S P I K
Sbjct: 347 RSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRS 406
Query: 327 PPP--KEAKDLSGRKSKRPVISQPHKSSSLVIHKARSN 362
P P + KD K + + + + S + K+ ++
Sbjct: 407 PSPRSRNKKDKKREKERDHISERRERERSTSMRKSSND 444
Score = 61.2 bits (147), Expect = 1e-09
Identities = 53/203 (26%), Positives = 93/203 (45%), Gaps = 7/203 (3%)
Query: 95 DVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPESRLTPWEVWFIGKEK 154
++ A E + R E Q S +E E+ + +++ S T + K
Sbjct: 149 EMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSH-TRSKSRSSSKSH 207
Query: 155 EERDRLQLKALEELNQQLEKRKEMEEREK----RKIIAEEKHKEWVQKKNEQKRKEREQK 210
R R Q K + + R++ R K ++ + E+ K + + KRK+ +K
Sbjct: 208 SRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREK 267
Query: 211 INKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEECERKKKEKEKEKQQQAEIQEKKE 270
I KE E K+ EKE +EK +EK +E K K+ ++ K +EK+KEK ++ E +EK+
Sbjct: 268 I-KEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRERE-REKEH 325
Query: 271 IAEKKFQEWLENAKHKPRPAAKS 293
++ ++ E K K R +S
Sbjct: 326 EKDRDKEKEKEQDKEKEREKDRS 348
Score = 37.7 bits (86), Expect = 0.017
Identities = 38/201 (18%), Positives = 74/201 (36%), Gaps = 37/201 (18%)
Query: 83 DGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPESRL 142
D + E + D E+D ++D R E + E E Q+++K+ S+
Sbjct: 300 DRDKEREKDREKDKEKDRE---------REREKEHEKDRDKEKEKEQDKEKEREKDRSK- 349
Query: 143 TPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQ----- 197
E+ EK ++D+ N R ER +R+ + + +
Sbjct: 350 ---EI----DEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRK 402
Query: 198 ----------KKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEE 247
K ++KR++ I++ E + + + K KEK + KN+
Sbjct: 403 SSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLE-----KNSTS 457
Query: 248 CERKKKEKEKEKQQQAEIQEK 268
+ K+ KE + E+ +K
Sbjct: 458 LKEKEHNKEPDSSVSKEVDDK 478
>gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens]
Length = 1303
Score = 66.2 bits (160), Expect = 4e-11
Identities = 67/299 (22%), Positives = 138/299 (46%), Gaps = 48/299 (16%)
Query: 82 GDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCAST-----QVESENNQE---EQK 133
G+ E+ E + ++D+H E + +S+ + + Q E+++N E +Q+
Sbjct: 314 GEKEETEYEYSGSEEEDDSHGEEGEPSSIMNVPGESTLRREFLRLQQENKSNSEALKQQQ 373
Query: 134 QVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHK 193
Q++ + R + + +++ R + +Q E+R+ +EE+++R E+ +
Sbjct: 374 QLQQQQQRDPEAHIKHLLHQRQRR----------IEEQKEERRRVEEQQRR-----EREQ 418
Query: 194 EWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQ-EWLKKKNAEECERKK 252
+Q+K +Q+R E Q + +E EE+ E E+EY +++ +E+ Q E L+++ +E K
Sbjct: 419 RKLQEKEQQRRLEDMQALRRE-EERRQAEREQEYKRKQLEEQRQSERLQRQLQQEHAYLK 477
Query: 253 KEKEKEKQQQAEIQEKKEIA---EKKFQEWLENAKHKPRPA--------AKSYGYANGKL 301
+++++QQQ + Q+++++ K + +PA + N L
Sbjct: 478 SLQQQQQQQQLQKQQQQQLLPGDRKPLYHYGRGMNPADKPAWAREVEERTRMNKQQNSPL 537
Query: 302 TGFYSGNSYPEPAF--YNPIPWKPIHMPPPKEAKDLSGRKSKRPVISQPHKSSSLVIHK 358
G++ PEP +P P P+ PP + RPV Q SLV H+
Sbjct: 538 AKSKPGSTGPEPPIPQASPGPPGPLSQTPPMQ----------RPVEPQEGPHKSLVAHR 586
>gi|27436917 misshapen/NIK-related kinase isoform 3 [Homo sapiens]
Length = 1332
Score = 66.2 bits (160), Expect = 4e-11
Identities = 67/299 (22%), Positives = 138/299 (46%), Gaps = 48/299 (16%)
Query: 82 GDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCAST-----QVESENNQE---EQK 133
G+ E+ E + ++D+H E + +S+ + + Q E+++N E +Q+
Sbjct: 314 GEKEETEYEYSGSEEEDDSHGEEGEPSSIMNVPGESTLRREFLRLQQENKSNSEALKQQQ 373
Query: 134 QVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHK 193
Q++ + R + + +++ R + +Q E+R+ +EE+++R E+ +
Sbjct: 374 QLQQQQQRDPEAHIKHLLHQRQRR----------IEEQKEERRRVEEQQRR-----EREQ 418
Query: 194 EWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQ-EWLKKKNAEECERKK 252
+Q+K +Q+R E Q + +E EE+ E E+EY +++ +E+ Q E L+++ +E K
Sbjct: 419 RKLQEKEQQRRLEDMQALRRE-EERRQAEREQEYKRKQLEEQRQSERLQRQLQQEHAYLK 477
Query: 253 KEKEKEKQQQAEIQEKKEIA---EKKFQEWLENAKHKPRPA--------AKSYGYANGKL 301
+++++QQQ + Q+++++ K + +PA + N L
Sbjct: 478 SLQQQQQQQQLQKQQQQQLLPGDRKPLYHYGRGMNPADKPAWAREVEERTRMNKQQNSPL 537
Query: 302 TGFYSGNSYPEPAF--YNPIPWKPIHMPPPKEAKDLSGRKSKRPVISQPHKSSSLVIHK 358
G++ PEP +P P P+ PP + RPV Q SLV H+
Sbjct: 538 AKSKPGSTGPEPPIPQASPGPPGPLSQTPPMQ----------RPVEPQEGPHKSLVAHR 586
>gi|7657335 misshapen/NIK-related kinase isoform 1 [Homo sapiens]
Length = 1295
Score = 66.2 bits (160), Expect = 4e-11
Identities = 67/299 (22%), Positives = 138/299 (46%), Gaps = 48/299 (16%)
Query: 82 GDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCAST-----QVESENNQE---EQK 133
G+ E+ E + ++D+H E + +S+ + + Q E+++N E +Q+
Sbjct: 314 GEKEETEYEYSGSEEEDDSHGEEGEPSSIMNVPGESTLRREFLRLQQENKSNSEALKQQQ 373
Query: 134 QVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHK 193
Q++ + R + + +++ R + +Q E+R+ +EE+++R E+ +
Sbjct: 374 QLQQQQQRDPEAHIKHLLHQRQRR----------IEEQKEERRRVEEQQRR-----EREQ 418
Query: 194 EWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQ-EWLKKKNAEECERKK 252
+Q+K +Q+R E Q + +E EE+ E E+EY +++ +E+ Q E L+++ +E K
Sbjct: 419 RKLQEKEQQRRLEDMQALRRE-EERRQAEREQEYKRKQLEEQRQSERLQRQLQQEHAYLK 477
Query: 253 KEKEKEKQQQAEIQEKKEIA---EKKFQEWLENAKHKPRPA--------AKSYGYANGKL 301
+++++QQQ + Q+++++ K + +PA + N L
Sbjct: 478 SLQQQQQQQQLQKQQQQQLLPGDRKPLYHYGRGMNPADKPAWAREVEERTRMNKQQNSPL 537
Query: 302 TGFYSGNSYPEPAF--YNPIPWKPIHMPPPKEAKDLSGRKSKRPVISQPHKSSSLVIHK 358
G++ PEP +P P P+ PP + RPV Q SLV H+
Sbjct: 538 AKSKPGSTGPEPPIPQASPGPPGPLSQTPPMQ----------RPVEPQEGPHKSLVAHR 586
>gi|22035606 mitogen-activated protein kinase kinase kinase kinase 4
isoform 3 [Homo sapiens]
Length = 1212
Score = 66.2 bits (160), Expect = 4e-11
Identities = 60/238 (25%), Positives = 115/238 (48%), Gaps = 29/238 (12%)
Query: 121 TQVESENNQEEQKQVRLPESRLTPWEVWFI-GKEKEERDRLQLKALEE------LNQQLE 173
T+ E ++EE+++V PE P + + G+ RD L+L+ + QQL
Sbjct: 319 TEYEYSGSEEEEEEV--PEQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQLL 376
Query: 174 KRKEMEERE--KRKIIAE-----EKHKEWVQKKNEQKRKEREQKINKEMEEKAAKELEKE 226
+ +++ E+E KR+++AE E+ KE ++ EQ+R+ERE + +E E++ ++ EK
Sbjct: 377 QEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKR 436
Query: 227 YLQEKAKEKYQEWLKKKNAEECERKKKEKEKEKQQQAEIQEKKEIAEKKF---QEWLENA 283
L+E + + +E +++ EE R ++E+E ++Q E Q E+ +++ Q L +
Sbjct: 437 RLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLLQEQAMLLHD 496
Query: 284 KHKPRPAAKSYGYANGKLTGFYSGNSYPEPAFYNPIPWKPIHMPPPKEAKDLSGRKSK 341
+P P +P+F+ P P H P A+++ R K
Sbjct: 497 HRRPHPQHSQQPPP--------PQQERSKPSFHAPEP--KAHYEPADRAREVEDRFRK 544
Score = 35.8 bits (81), Expect = 0.064
Identities = 36/145 (24%), Positives = 76/145 (52%), Gaps = 12/145 (8%)
Query: 149 FIGKEKEERD-RLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQKKNEQKRKER 207
FI + ER R+QLK + +++ +KR E +E E +EE+ +E +++ E
Sbjct: 288 FIRDQPNERQVRIQLK--DHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPS---- 341
Query: 208 EQKINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEECERKKKEKEKEKQQQAEIQE 267
+N E ++ + LQ++ KE+ E L+++ + E++ +E+E+ K+Q ++
Sbjct: 342 -SIVNVPGESTLRRDFLR--LQQENKER-SEALRRQQLLQ-EQQLREQEEYKRQLLAERQ 396
Query: 268 KKEIAEKKFQEWLENAKHKPRPAAK 292
K+ +K+ + LE + + R A +
Sbjct: 397 KRIEQQKEQRRRLEEQQRREREARR 421
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 65.5 bits (158), Expect = 8e-11
Identities = 59/219 (26%), Positives = 109/219 (49%), Gaps = 30/219 (13%)
Query: 85 EDEEDVDDEEDV----DEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPES 140
E EE + ++ED +E + E K+ + + + E QE+++++ E
Sbjct: 336 EQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEE 395
Query: 141 RLTPWE------VWFIGKEKEERDRLQLKALEELNQQLEKRKEMEE----REKRKIIAEE 190
++ E +W K+ E+D + EE+ +Q EK +E+EE +E++ EE
Sbjct: 396 KIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEE 455
Query: 191 KHKEWVQKKNEQKRK--EREQKINKEME-----EKAAKELEKEYLQEKAKEKYQEWLKKK 243
K +E +K EQ+ K +E+KI ++ E EK K+ EK + QE+ + W +++
Sbjct: 456 KMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEE-----KMWRQEE 510
Query: 244 NAEECERKKKEKEKEKQQQAEIQEKKEI----AEKKFQE 278
E E K +E+E++ Q+Q E ++E+ E+K QE
Sbjct: 511 KMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQE 549
Score = 64.7 bits (156), Expect = 1e-10
Identities = 45/157 (28%), Positives = 95/157 (60%), Gaps = 13/157 (8%)
Query: 124 ESENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKAL----EELNQQLEKRKEME 179
+ E E+++++R E ++ W +E+EE+ R Q + + E++ +Q EK +E E
Sbjct: 330 QEEKMHEQEEKIREQEDKM--WRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQE 387
Query: 180 E---REKRKIIAEEKHKEWVQKKNEQKRKEREQKINKEMEE---KAAKELEKEYLQEKAK 233
E R++ KI +E+ ++ + E+K +E+++KI ++ EE + K E E + + +
Sbjct: 388 EEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQE 447
Query: 234 EKYQEWLKKKNAEECERKKKEKEKEKQQQAEIQEKKE 270
EK +E +++K EE E+ ++++EK ++Q+ +IQE++E
Sbjct: 448 EKLRE-VEEKMQEEEEKMQEQEEKIQRQEEKIQEQEE 483
Score = 62.0 bits (149), Expect = 8e-10
Identities = 55/184 (29%), Positives = 99/184 (53%), Gaps = 27/184 (14%)
Query: 112 GMELQGCAS---TQVESE------NNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQL 162
G ELQ ++ QVE N Q+E+K R E I +++E+ +L
Sbjct: 268 GKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEK---------IQEQEEKMCEQEL 318
Query: 163 KALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQKKNEQKRKEREQKINKEMEEKAAKE 222
K E+ + + ++M E+E++ I E++ K W Q E+K +E+E+KI +E EEK ++
Sbjct: 319 KIREQEEKMWRQEEKMHEQEEK--IREQEDKMWRQ---EEKIREQEEKI-REQEEKMWRQ 372
Query: 223 LEKEYLQ-EKAKEKYQE-WLKKKNAEECERKKKEKEKEKQQQAEIQEKKEIAEKKFQEWL 280
EK Q EK +E+ +E W +++ E E K++EK ++++ Q++K I E++ + W
Sbjct: 373 EEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEK-IREQEEEMWR 431
Query: 281 ENAK 284
+ K
Sbjct: 432 QEEK 435
Score = 58.2 bits (139), Expect = 1e-08
Identities = 44/197 (22%), Positives = 104/197 (52%), Gaps = 8/197 (4%)
Query: 85 EDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPESRLTP 144
++E+ + +E + E + + +R E + + + +E+ +++R E +
Sbjct: 372 QEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEM-- 429
Query: 145 WEVWFIGKEKEERDRLQLKALEELNQQLEKRKE-MEEREKRKIIAEEKHKEWVQKKNEQK 203
W +E EE + Q + L E+ +++++ +E M+E+E++ EEK +E +K Q+
Sbjct: 430 WRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQE 489
Query: 204 RKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEECERKKKEKEKEKQQQA 263
+ ++++ E EEK ++ EK + QE+ ++ +E ++++ E K +E+E QQ
Sbjct: 490 KLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQ-----EEKMREQEVRLWQQE 544
Query: 264 EIQEKKEIAEKKFQEWL 280
E +++E+ ++ +E L
Sbjct: 545 EKMQEQEVRLQELEERL 561
Score = 49.3 bits (116), Expect = 6e-06
Identities = 45/197 (22%), Positives = 100/197 (50%), Gaps = 19/197 (9%)
Query: 78 DEDDGDGEDEEDV-DDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVR 136
++D+ E EE++ EE + E + K+ + + + E +++++R
Sbjct: 378 EQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIR 437
Query: 137 LPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWV 196
E + E +E EE+ + + + ++E +++++++E I E++ K W
Sbjct: 438 ELEEMMQDQEEKL--REVEEKMQEEEEKMQEQEEKIQRQEEK--------IQEQEEKTWR 487
Query: 197 QK---KNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEECERKKK 253
Q+ K E+K E+E+K+ ++ EEK ++ EK QE+ ++ +E K E+ R +
Sbjct: 488 QEKLLKQEEKIWEQEEKMWRQ-EEKMWEQEEKMQEQEEKMQRQEE----KMREQEVRLWQ 542
Query: 254 EKEKEKQQQAEIQEKKE 270
++EK ++Q+ +QE +E
Sbjct: 543 QEEKMQEQEVRLQELEE 559
Score = 47.8 bits (112), Expect = 2e-05
Identities = 49/197 (24%), Positives = 98/197 (49%), Gaps = 19/197 (9%)
Query: 78 DEDDGDGEDEEDVDDEED----VDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQK 133
++D+ E EE++ +E+ ++E D E K LR +E Q E E QE+++
Sbjct: 417 EQDEKIREQEEEMWRQEEKIRELEEMMQDQEEK---LREVE----EKMQEEEEKMQEQEE 469
Query: 134 QVRLPESRLTP-----WEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIA 188
+++ E ++ W + K++E+ + K + + E+ ++M+E+E++
Sbjct: 470 KIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQ 529
Query: 189 EEKHKEWVQKKNEQKRKEREQKIN-KEMEEKAAKELEK-EYLQEKAKEKYQEWLKKKN-A 245
EEK +E + +Q+ K +EQ++ +E+EE+ K +K E L +E + L
Sbjct: 530 EEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPI 589
Query: 246 EECERKKKEKEKEKQQQ 262
+ E K +E + +QQQ
Sbjct: 590 LQVELKSQEAQSLQQQQ 606
Score = 28.9 bits (63), Expect = 7.8
Identities = 33/131 (25%), Positives = 54/131 (41%), Gaps = 15/131 (11%)
Query: 163 KALEELNQQLEKRKE-MEERE----KRKIIAEEKHKEWVQKKNEQKRKEREQKINKEMEE 217
K +E+ +KR+E M E+ KR +I K W++ +K E + +E
Sbjct: 126 KNSDEVKSSFKKRQEKMNEKNYTFRKRVVIK----KPWLRLGEVTAQKRPENSLLEETLH 181
Query: 218 KAAKELEKEYLQEKAKEKYQEWLKKKNAEECERKKKEKEKEKQQQAEIQEKKEIAEKKFQ 277
Y+++ KE+ L E R E+ K++ AE+QEK + E +
Sbjct: 182 FDHAVRMGTYIEKLTKERDAPSL------ELYRNTITDEELKEKNAELQEKLRLVESEKS 235
Query: 278 EWLENAKHKPR 288
E N K R
Sbjct: 236 EIQLNVKDLKR 246
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 65.5 bits (158), Expect = 8e-11
Identities = 59/219 (26%), Positives = 109/219 (49%), Gaps = 30/219 (13%)
Query: 85 EDEEDVDDEEDV----DEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPES 140
E EE + ++ED +E + E K+ + + + E QE+++++ E
Sbjct: 336 EQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEE 395
Query: 141 RLTPWE------VWFIGKEKEERDRLQLKALEELNQQLEKRKEMEE----REKRKIIAEE 190
++ E +W K+ E+D + EE+ +Q EK +E+EE +E++ EE
Sbjct: 396 KIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEE 455
Query: 191 KHKEWVQKKNEQKRK--EREQKINKEME-----EKAAKELEKEYLQEKAKEKYQEWLKKK 243
K +E +K EQ+ K +E+KI ++ E EK K+ EK + QE+ + W +++
Sbjct: 456 KMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEE-----KMWRQEE 510
Query: 244 NAEECERKKKEKEKEKQQQAEIQEKKEI----AEKKFQE 278
E E K +E+E++ Q+Q E ++E+ E+K QE
Sbjct: 511 KMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQE 549
Score = 64.7 bits (156), Expect = 1e-10
Identities = 45/157 (28%), Positives = 95/157 (60%), Gaps = 13/157 (8%)
Query: 124 ESENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKAL----EELNQQLEKRKEME 179
+ E E+++++R E ++ W +E+EE+ R Q + + E++ +Q EK +E E
Sbjct: 330 QEEKMHEQEEKIREQEDKM--WRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQE 387
Query: 180 E---REKRKIIAEEKHKEWVQKKNEQKRKEREQKINKEMEE---KAAKELEKEYLQEKAK 233
E R++ KI +E+ ++ + E+K +E+++KI ++ EE + K E E + + +
Sbjct: 388 EEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQE 447
Query: 234 EKYQEWLKKKNAEECERKKKEKEKEKQQQAEIQEKKE 270
EK +E +++K EE E+ ++++EK ++Q+ +IQE++E
Sbjct: 448 EKLRE-VEEKMQEEEEKMQEQEEKIQRQEEKIQEQEE 483
Score = 62.0 bits (149), Expect = 8e-10
Identities = 55/184 (29%), Positives = 99/184 (53%), Gaps = 27/184 (14%)
Query: 112 GMELQGCAS---TQVESE------NNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQL 162
G ELQ ++ QVE N Q+E+K R E I +++E+ +L
Sbjct: 268 GKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEK---------IQEQEEKMCEQEL 318
Query: 163 KALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQKKNEQKRKEREQKINKEMEEKAAKE 222
K E+ + + ++M E+E++ I E++ K W Q E+K +E+E+KI +E EEK ++
Sbjct: 319 KIREQEEKMWRQEEKMHEQEEK--IREQEDKMWRQ---EEKIREQEEKI-REQEEKMWRQ 372
Query: 223 LEKEYLQ-EKAKEKYQE-WLKKKNAEECERKKKEKEKEKQQQAEIQEKKEIAEKKFQEWL 280
EK Q EK +E+ +E W +++ E E K++EK ++++ Q++K I E++ + W
Sbjct: 373 EEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEK-IREQEEEMWR 431
Query: 281 ENAK 284
+ K
Sbjct: 432 QEEK 435
Score = 58.2 bits (139), Expect = 1e-08
Identities = 44/197 (22%), Positives = 104/197 (52%), Gaps = 8/197 (4%)
Query: 85 EDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPESRLTP 144
++E+ + +E + E + + +R E + + + +E+ +++R E +
Sbjct: 372 QEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEM-- 429
Query: 145 WEVWFIGKEKEERDRLQLKALEELNQQLEKRKE-MEEREKRKIIAEEKHKEWVQKKNEQK 203
W +E EE + Q + L E+ +++++ +E M+E+E++ EEK +E +K Q+
Sbjct: 430 WRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQE 489
Query: 204 RKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEECERKKKEKEKEKQQQA 263
+ ++++ E EEK ++ EK + QE+ ++ +E ++++ E K +E+E QQ
Sbjct: 490 KLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQ-----EEKMREQEVRLWQQE 544
Query: 264 EIQEKKEIAEKKFQEWL 280
E +++E+ ++ +E L
Sbjct: 545 EKMQEQEVRLQELEERL 561
Score = 49.3 bits (116), Expect = 6e-06
Identities = 45/197 (22%), Positives = 100/197 (50%), Gaps = 19/197 (9%)
Query: 78 DEDDGDGEDEEDV-DDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVR 136
++D+ E EE++ EE + E + K+ + + + E +++++R
Sbjct: 378 EQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIR 437
Query: 137 LPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWV 196
E + E +E EE+ + + + ++E +++++++E I E++ K W
Sbjct: 438 ELEEMMQDQEEKL--REVEEKMQEEEEKMQEQEEKIQRQEEK--------IQEQEEKTWR 487
Query: 197 QK---KNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEECERKKK 253
Q+ K E+K E+E+K+ ++ EEK ++ EK QE+ ++ +E K E+ R +
Sbjct: 488 QEKLLKQEEKIWEQEEKMWRQ-EEKMWEQEEKMQEQEEKMQRQEE----KMREQEVRLWQ 542
Query: 254 EKEKEKQQQAEIQEKKE 270
++EK ++Q+ +QE +E
Sbjct: 543 QEEKMQEQEVRLQELEE 559
Score = 47.8 bits (112), Expect = 2e-05
Identities = 49/197 (24%), Positives = 98/197 (49%), Gaps = 19/197 (9%)
Query: 78 DEDDGDGEDEEDVDDEED----VDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQK 133
++D+ E EE++ +E+ ++E D E K LR +E Q E E QE+++
Sbjct: 417 EQDEKIREQEEEMWRQEEKIRELEEMMQDQEEK---LREVE----EKMQEEEEKMQEQEE 469
Query: 134 QVRLPESRLTP-----WEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIA 188
+++ E ++ W + K++E+ + K + + E+ ++M+E+E++
Sbjct: 470 KIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQ 529
Query: 189 EEKHKEWVQKKNEQKRKEREQKIN-KEMEEKAAKELEK-EYLQEKAKEKYQEWLKKKN-A 245
EEK +E + +Q+ K +EQ++ +E+EE+ K +K E L +E + L
Sbjct: 530 EEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPI 589
Query: 246 EECERKKKEKEKEKQQQ 262
+ E K +E + +QQQ
Sbjct: 590 LQVELKSQEAQSLQQQQ 606
>gi|22035604 mitogen-activated protein kinase kinase kinase kinase 4
isoform 2 [Homo sapiens]
Length = 1320
Score = 65.1 bits (157), Expect = 1e-10
Identities = 50/189 (26%), Positives = 100/189 (52%), Gaps = 25/189 (13%)
Query: 121 TQVESENNQEEQKQVRLPESRLTPWEVWFI-GKEKEERDRLQLKALEE------LNQQLE 173
T+ E ++EE+++V PE P + + G+ RD L+L+ + QQL
Sbjct: 319 TEYEYSGSEEEEEEV--PEQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQLL 376
Query: 174 KRKEMEERE--KRKIIAE-----EKHKEWVQKKNEQKRKEREQKINKEMEEKAAKELEKE 226
+ +++ E+E KR+++AE E+ KE ++ EQ+R+ERE + +E E++ ++ EK
Sbjct: 377 QEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKR 436
Query: 227 YLQEKAKEKYQEWLKKKNAEECERKKKEKEKEKQQQAEIQEKKEIAEKKFQE-------- 278
L+E + + +E +++ EE R ++E+E ++Q E Q E+ +++ +
Sbjct: 437 RLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLLQEQAMLLEC 496
Query: 279 -WLENAKHK 286
W E +H+
Sbjct: 497 RWREMEEHR 505
Score = 53.1 bits (126), Expect = 4e-07
Identities = 51/209 (24%), Positives = 102/209 (48%), Gaps = 26/209 (12%)
Query: 79 EDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRG-MELQGCASTQVESENNQEEQKQVRL 137
E G E+EE+V ++E + + R + LQ Q E ++ ++Q L
Sbjct: 322 EYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQ-----QENKERSEALRRQQLL 376
Query: 138 PESRLTPWEVWF----------IGKEKEERDRL---QLKALEELNQQLEKRKEMEEREKR 184
E +L E + I ++KE+R RL Q + E QQ +++ E+ EKR
Sbjct: 377 QEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKR 436
Query: 185 KIIAEEKHKEWVQKKN----EQKRKEREQK-INKEMEEKAA--KELEKEYLQEKAKEKYQ 237
++ E+ ++ +++ E++R EREQ+ I +++EE+ + L+++ LQE+A
Sbjct: 437 RLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLLQEQAMLLEC 496
Query: 238 EWLKKKNAEECERKKKEKEKEKQQQAEIQ 266
W + + + ER +++ ++E+ +Q
Sbjct: 497 RWREMEEHRQAERLQRQLQQEQAYLLSLQ 525
Score = 40.8 bits (94), Expect = 0.002
Identities = 42/163 (25%), Positives = 79/163 (48%), Gaps = 32/163 (19%)
Query: 149 FIGKEKEERD-RLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQKKNEQK---- 203
FI + ER R+QLK + +++ +KR E +E E +EE+ +E +++ E
Sbjct: 288 FIRDQPNERQVRIQLK--DHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVN 345
Query: 204 -------RKE--REQKINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEECERKKKE 254
R++ R Q+ NKE E ++ + LQE+ + +E+ ++ AE +R +++
Sbjct: 346 VPGESTLRRDFLRLQQENKERSEALRRQ---QLLQEQQLREQEEYKRQLLAERQKRIEQQ 402
Query: 255 KEKE-------------KQQQAEIQEKKEIAEKKFQEWLENAK 284
KE+ ++QQ Q ++E EK+ E LE +
Sbjct: 403 KEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRR 445
>gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]
Length = 202
Score = 64.7 bits (156), Expect = 1e-10
Identities = 49/200 (24%), Positives = 96/200 (48%), Gaps = 10/200 (5%)
Query: 104 EAKVASLRGMELQGCASTQVESENNQEEQKQVRLPESRLTPWEVWFIGKEKE---ERDRL 160
E K + RG E + Q E EN E + + R + KE+E ERDR
Sbjct: 6 ERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQ 65
Query: 161 QLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQKKNEQKRKEREQKINKEMEEKAA 220
+ + E + +R+ +RE+++ E+ K+ + ++RE N+E K
Sbjct: 66 RQRERETERETERQRERQRQRERKRQTDRERDKD------RDRERKRETDRNRERNRKGG 119
Query: 221 KELEKEYLQEKAKEKYQEWLKKKNAEECERKKKEKEKEKQQQAEIQE-KKEIAEKKFQEW 279
+E +K+ +E+ +E+ ++ +++ + +K+E ++E+Q+ AE +E KKE +++ +E
Sbjct: 120 RERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKER 179
Query: 280 LENAKHKPRPAAKSYGYANG 299
E K + R K + G
Sbjct: 180 KEKKKEEKRREDKKRKWGEG 199
Score = 40.0 bits (92), Expect = 0.003
Identities = 18/86 (20%), Positives = 52/86 (60%), Gaps = 1/86 (1%)
Query: 180 EREKRKIIAEEKHKEWVQKKNEQKRKERE-QKINKEMEEKAAKELEKEYLQEKAKEKYQE 238
ER++ + ++ KE ++++ Q+ +E + ++ N+ + +E +++ +EK +E+ +E
Sbjct: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61
Query: 239 WLKKKNAEECERKKKEKEKEKQQQAE 264
+++ E ++ E+++E+Q+Q E
Sbjct: 62 RDRQRQRERETERETERQRERQRQRE 87
Score = 37.7 bits (86), Expect = 0.017
Identities = 20/105 (19%), Positives = 56/105 (53%), Gaps = 1/105 (0%)
Query: 172 LEKRKEMEEREKRKIIAEEKHKEWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEK 231
+E+++E + R E + +++N+ +R+ R ++ ++ E + EKE ++K
Sbjct: 1 MERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQK 60
Query: 232 AKEKYQEWLKKKNAE-ECERKKKEKEKEKQQQAEIQEKKEIAEKK 275
+++ ++ ++ E E +R+++ + + K+Q ++K E+K
Sbjct: 61 ERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERK 105
Score = 32.3 bits (72), Expect = 0.71
Identities = 26/105 (24%), Positives = 57/105 (54%), Gaps = 10/105 (9%)
Query: 190 EKHKEWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEECE 249
E+ +E ++ + K ERE+ +E E + +E + +++ +E+ ++ ++K E E
Sbjct: 2 ERQRERKRETDRGKETERERDRQRERENQTERE-NRHRQRDRHRERDRQTDREK---ERE 57
Query: 250 RKK-----KEKEKEKQQQAEIQ-EKKEIAEKKFQEWLENAKHKPR 288
R+K +++E+E +++ E Q E++ E+K Q E K + R
Sbjct: 58 RQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDR 102
Score = 30.8 bits (68), Expect = 2.1
Identities = 32/120 (26%), Positives = 52/120 (43%), Gaps = 19/120 (15%)
Query: 85 EDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCAST----QVESENNQEEQKQVRLPES 140
E + D E D D D E K + R E Q E E ++E ++Q +
Sbjct: 87 ERKRQTDRERDKDRDR---ERKRETDRNRERNRKGGRERDKQTERERDRERERQRQRERE 143
Query: 141 RLTPWEVWFIGKEKEERDRLQLKALEELNQQLEK-----RKEMEEREKRKIIAEEKHKEW 195
R E K + +R+R + EE ++ +K RKE ++ EKR+ E+K ++W
Sbjct: 144 RQRQRE----RKRETDRERQRWAEREERKKERKKERKKERKEKKKEEKRR---EDKKRKW 196
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.126 0.367
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,418,282
Number of Sequences: 37866
Number of extensions: 1038346
Number of successful extensions: 42841
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1069
Number of HSP's successfully gapped in prelim test: 1270
Number of HSP's that attempted gapping in prelim test: 9181
Number of HSP's gapped (non-prelim): 14064
length of query: 373
length of database: 18,247,518
effective HSP length: 104
effective length of query: 269
effective length of database: 14,309,454
effective search space: 3849243126
effective search space used: 3849243126
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.