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Search of human proteins with 62865885
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|62865885 connexin 37 [Homo sapiens]
(333 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|62865885 connexin 37 [Homo sapiens] 684 0.0
gi|22779877 connexin 46 [Homo sapiens] 304 6e-83
gi|4504001 connexin 43 [Homo sapiens] 303 2e-82
gi|32483412 connexin 40 [Homo sapiens] 276 2e-74
gi|6631083 connexin 40 [Homo sapiens] 276 2e-74
gi|55953076 connexin 50 [Homo sapiens] 265 6e-71
gi|31542845 gap junction protein, alpha 9, 59kDa [Homo sapiens] 264 9e-71
gi|14211941 gap junction protein, alpha 10 [Homo sapiens] 257 1e-68
gi|122939172 connexin 45 [Homo sapiens] 223 1e-58
gi|69122473 connexin 45 [Homo sapiens] 223 1e-58
gi|42558283 gap junction protein beta 2 [Homo sapiens] 220 2e-57
gi|45439367 gap junction protein, gamma 2, 47kDa [Homo sapiens] 217 1e-56
gi|159032020 gap junction protein, beta 6 [Homo sapiens] 215 4e-56
gi|158966714 gap junction protein, beta 6 [Homo sapiens] 215 4e-56
gi|158966717 gap junction protein, beta 6 [Homo sapiens] 215 4e-56
gi|40254837 gap junction protein, beta 6 [Homo sapiens] 215 4e-56
gi|148233402 gap junction protein, beta 1, 32kDa [Homo sapiens] 206 3e-53
gi|4504005 gap junction protein, beta 1, 32kDa [Homo sapiens] 206 3e-53
gi|54607056 connexin 31 [Homo sapiens] 199 2e-51
gi|13128960 connexin 31 [Homo sapiens] 199 2e-51
gi|23397464 gap junction protein, beta 4 [Homo sapiens] 194 1e-49
gi|10190698 gap junction protein, delta 2, 36kDa [Homo sapiens] 192 5e-49
gi|10835079 gap junction protein, beta 5, 31.1kDa [Homo sapiens] 189 3e-48
gi|148839378 gap junction protein, delta 3, 31.9kDa [Homo sapiens] 187 1e-47
gi|38348412 gap junction protein, beta 7, 25kDa [Homo sapiens] 182 3e-46
gi|145699105 connexin40.1 [Homo sapiens] 145 4e-35
gi|31559821 gap junction protein, gamma 3, 30.2kDa [Homo sapiens] 141 9e-34
gi|169171704 PREDICTED: similar to hCG1770601 [Homo sapiens] 90 2e-18
gi|169171845 PREDICTED: similar to hCG1770601 [Homo sapiens] 90 2e-18
gi|169171183 PREDICTED: similar to hCG1770601 [Homo sapiens] 90 2e-18
>gi|62865885 connexin 37 [Homo sapiens]
Length = 333
Score = 684 bits (1765), Expect = 0.0
Identities = 333/333 (100%), Positives = 333/333 (100%)
Query: 1 MGDWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPG 60
MGDWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPG
Sbjct: 1 MGDWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPG 60
Query: 61 CTNVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKD 120
CTNVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKD
Sbjct: 61 CTNVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKD 120
Query: 121 PQVERALAAVERQMAKISVAEDGRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLYGWT 180
PQVERALAAVERQMAKISVAEDGRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLYGWT
Sbjct: 121 PQVERALAAVERQMAKISVAEDGRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLYGWT 180
Query: 181 MEPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCLSRGM 240
MEPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCLSRGM
Sbjct: 181 MEPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCLSRGM 240
Query: 241 RARQGQDAPPTQGTSSDPYTDQVFFYLPVGQGPSSPPCPTYNGLSSSEQNWANLTTEERL 300
RARQGQDAPPTQGTSSDPYTDQVFFYLPVGQGPSSPPCPTYNGLSSSEQNWANLTTEERL
Sbjct: 241 RARQGQDAPPTQGTSSDPYTDQVFFYLPVGQGPSSPPCPTYNGLSSSEQNWANLTTEERL 300
Query: 301 ASSRPPLFLDPPPQNGQKPPSRPSSSASKKQYV 333
ASSRPPLFLDPPPQNGQKPPSRPSSSASKKQYV
Sbjct: 301 ASSRPPLFLDPPPQNGQKPPSRPSSSASKKQYV 333
>gi|22779877 connexin 46 [Homo sapiens]
Length = 435
Score = 304 bits (779), Expect = 6e-83
Identities = 172/374 (45%), Positives = 224/374 (59%), Gaps = 62/374 (16%)
Query: 1 MGDWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPG 60
MGDW FL +LL+ QEHSTV+GK+WLTVLFIFRIL+LG A E VWGDEQSDF CNT QPG
Sbjct: 1 MGDWSFLGRLLENAQEHSTVIGKVWLTVLFIFRILVLGAAAEDVWGDEQSDFTCNTQQPG 60
Query: 61 CTNVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGE---LRALP 117
C NVCYD+AFPISHIR+W LQ +FVSTPTL+YLGHV+++ R EE+ +++E E R P
Sbjct: 61 CENVCYDRAFPISHIRFWALQIIFVSTPTLIYLGHVLHIVRMEEKKKEREEEEQLKRESP 120
Query: 118 A-KDPQVERALAAVERQMAKISVAEDGRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRL 176
+ K+P + + +R GR+R+ GAL+ TYV +++ K++ E GF+ GQ+ L
Sbjct: 121 SPKEPPQDNPSSRDDR----------GRVRMAGALLRTYVFNIIFKTLFEVGFIAGQYFL 170
Query: 177 YGWTMEPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCL 236
YG+ ++P++ C R PCP VDCF+SRPTEKTIFIIFML V SL+LN+LE+ HL + L
Sbjct: 171 YGFELKPLYRCDRWPCPNTVDCFISRPTEKTIFIIFMLAVACASLLLNMLEIYHLGWKKL 230
Query: 237 SRGMRARQGQDA---------PPTQGTSSDPYTDQVFF-------YLPVGQG-----PSS 275
+G+ +R G DA PP SS P + F P+GQ P +
Sbjct: 231 KQGVTSRLGPDASEAPLGTADPPPLPPSSRPPAVAIGFPPYYAHTAAPLGQARAVGYPGA 290
Query: 276 PP-------------------CPTYNG---LSSSEQNWANLTTEERLASSRPPLFLDPPP 313
PP YNG L +EQNWAN + A +PP P
Sbjct: 291 PPPAADFKLLALTEARGKGQSAKLYNGHHHLLMTEQNWAN-----QAAERQPPALKAYPA 345
Query: 314 QNGQKPPSRPSSSA 327
+ PS SS+
Sbjct: 346 ASTPAAPSPVGSSS 359
>gi|4504001 connexin 43 [Homo sapiens]
Length = 382
Score = 303 bits (775), Expect = 2e-82
Identities = 157/322 (48%), Positives = 206/322 (63%), Gaps = 29/322 (9%)
Query: 1 MGDWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPG 60
MGDW L KLLD+VQ +ST GK+WL+VLFIFRIL+LG A ES WGDEQS F CNT QPG
Sbjct: 1 MGDWSALGKLLDKVQAYSTAGGKVWLSVLFIFRILLLGTAVESAWGDEQSAFRCNTQQPG 60
Query: 61 CTNVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKD 120
C NVCYD++FPISH+R+WVLQ +FVS PTL+YL HV Y+ R+EE+L +KE EL+
Sbjct: 61 CENVCYDKSFPISHVRFWVLQIIFVSVPTLLYLAHVFYVMRKEEKLNKKEEELKVAQTDG 120
Query: 121 PQVERALAAVERQMAKISVAEDGRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLYGWT 180
V+ L +E + K + E G++++RG L+ TY+ S+L KS+ E FL QW +YG++
Sbjct: 121 VNVDMHLKQIEIKKFKYGIEEHGKVKMRGGLLRTYIISILFKSIFEVAFLLIQWYIYGFS 180
Query: 181 MEPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCLSRGM 240
+ V+ C+R PCP+ VDCF+SRPTEKTIFIIFMLVV L+SL LN++EL ++ +G+
Sbjct: 181 LSAVYTCKRDPCPHQVDCFLSRPTEKTIFIIFMLVVSLVSLALNIIELFYV----FFKGV 236
Query: 241 RARQGQDAPPTQGTSS--DPYTD---QVFFYL------PVGQGPSSPP------------ 277
+ R + P TS P D Q + Y P SPP
Sbjct: 237 KDRVKGKSDPYHATSGALSPAKDCGSQKYAYFNGCSSPTAPLSPMSPPGYKLVTGDRNNS 296
Query: 278 -CPTYNGLSSSEQNWANLTTEE 298
C YN +SEQNWAN + E+
Sbjct: 297 SCRNYN-KQASEQNWANYSAEQ 317
>gi|32483412 connexin 40 [Homo sapiens]
Length = 358
Score = 276 bits (705), Expect = 2e-74
Identities = 147/325 (45%), Positives = 206/325 (63%), Gaps = 10/325 (3%)
Query: 1 MGDWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPG 60
MGDW FL L++V +HSTVVGK+WLTVLFIFR+L+LG A ES WGDEQ+DF C+T QPG
Sbjct: 1 MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG 60
Query: 61 CTNVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKD 120
C NVCYDQAFPISHIRYWVLQ +FVSTP+LVY+GH ++ R +E+ + +E E AK+
Sbjct: 61 CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAE----RAKE 116
Query: 121 PQVERALAAVERQMAKISVAED--GRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLYG 178
+ + + A++S E+ GR+ ++G L+ TYV S+L ++ +E GF+ GQ+ +YG
Sbjct: 117 VRGSGSYEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYG 176
Query: 179 WTMEPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCL-S 237
+ + VC+R+PCP+ V+C+VSRPTEK +FI+FML V +SL+L+L EL HL + +
Sbjct: 177 IFLTTLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQ 236
Query: 238 RGMRARQGQDAPPTQGTS---SDPYTDQVFFYLPVGQGPSSPPCPTYNGLSSSEQNWANL 294
R ++ RQ G S T F + GP ++ +S+QN NL
Sbjct: 237 RFVKPRQHMAKCQLSGPSVGIVQSCTPPPDFNQCLENGPGGKFFNPFSNNMASQQNTDNL 296
Query: 295 TTEERLASSRPPLFLDPPPQNGQKP 319
TE+ + P + GQKP
Sbjct: 297 VTEQVRGQEQTPGEGFIQVRYGQKP 321
>gi|6631083 connexin 40 [Homo sapiens]
Length = 358
Score = 276 bits (705), Expect = 2e-74
Identities = 147/325 (45%), Positives = 206/325 (63%), Gaps = 10/325 (3%)
Query: 1 MGDWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPG 60
MGDW FL L++V +HSTVVGK+WLTVLFIFR+L+LG A ES WGDEQ+DF C+T QPG
Sbjct: 1 MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG 60
Query: 61 CTNVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKD 120
C NVCYDQAFPISHIRYWVLQ +FVSTP+LVY+GH ++ R +E+ + +E E AK+
Sbjct: 61 CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAE----RAKE 116
Query: 121 PQVERALAAVERQMAKISVAED--GRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLYG 178
+ + + A++S E+ GR+ ++G L+ TYV S+L ++ +E GF+ GQ+ +YG
Sbjct: 117 VRGSGSYEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYG 176
Query: 179 WTMEPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCL-S 237
+ + VC+R+PCP+ V+C+VSRPTEK +FI+FML V +SL+L+L EL HL + +
Sbjct: 177 IFLTTLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQ 236
Query: 238 RGMRARQGQDAPPTQGTS---SDPYTDQVFFYLPVGQGPSSPPCPTYNGLSSSEQNWANL 294
R ++ RQ G S T F + GP ++ +S+QN NL
Sbjct: 237 RFVKPRQHMAKCQLSGPSVGIVQSCTPPPDFNQCLENGPGGKFFNPFSNNMASQQNTDNL 296
Query: 295 TTEERLASSRPPLFLDPPPQNGQKP 319
TE+ + P + GQKP
Sbjct: 297 VTEQVRGQEQTPGEGFIQVRYGQKP 321
>gi|55953076 connexin 50 [Homo sapiens]
Length = 433
Score = 265 bits (676), Expect = 6e-71
Identities = 127/233 (54%), Positives = 165/233 (70%), Gaps = 8/233 (3%)
Query: 1 MGDWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPG 60
MGDW FL +L++V EHSTV+G++WLTVLFIFRILILG A E VWGDEQSDF CNT QPG
Sbjct: 1 MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPG 60
Query: 61 CTNVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKD 120
C NVCYD+AFPISHIR WVLQ +FVSTP+L+Y+GH ++ R EE+ + +E E +
Sbjct: 61 CENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAE------EL 114
Query: 121 PQVERALAAVERQMAKISVAEDG--RLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLYG 178
Q ++ K S G + R+ G L+ TY+ ++ K++ E GF+ G + LYG
Sbjct: 115 GQQAGTNGGPDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYG 174
Query: 179 WTMEPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHL 231
+ + P++ C R PCP +VDCFVSRPTEKTIFI+FML V +SL LN++EL HL
Sbjct: 175 FRILPLYRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHL 227
>gi|31542845 gap junction protein, alpha 9, 59kDa [Homo sapiens]
Length = 515
Score = 264 bits (674), Expect = 9e-71
Identities = 126/242 (52%), Positives = 170/242 (70%), Gaps = 2/242 (0%)
Query: 1 MGDWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPG 60
MGDW L L++V HST++GKIWLT+LFIFR+L+LG+A E VW DEQS F CNT QPG
Sbjct: 1 MGDWNLLGDTLEEVHIHSTMIGKIWLTILFIFRMLVLGVAAEDVWNDEQSGFICNTEQPG 60
Query: 61 CTNVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSR--REERLRQKEGELRALPA 118
C NVCYDQAFPIS IRYWVLQ +FVS+P+LVY+GH +Y R EER R K L
Sbjct: 61 CRNVCYDQAFPISLIRYWVLQVIFVSSPSLVYMGHALYRLRVLEEERQRMKAQLRVELEE 120
Query: 119 KDPQVERALAAVERQMAKISVAEDGRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLYG 178
+ ++ R +E+++ ++ + + +RG L+ TYV + +SV+E GF+ GQ+ LYG
Sbjct: 121 VEFEMPRDRRRLEQELCQLEKRKLNKAPLRGTLLCTYVIHIFTRSVVEVGFMIGQYLLYG 180
Query: 179 WTMEPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCLSR 238
+ +EP+F C PCP ++DCFVSRPTEKTIF++FM + ISL LN+LE+ HL + + R
Sbjct: 181 FHLEPLFKCHGHPCPNIIDCFVSRPTEKTIFLLFMQSIATISLFLNILEIFHLGFKKIKR 240
Query: 239 GM 240
G+
Sbjct: 241 GL 242
>gi|14211941 gap junction protein, alpha 10 [Homo sapiens]
Length = 543
Score = 257 bits (656), Expect = 1e-68
Identities = 125/250 (50%), Positives = 176/250 (70%), Gaps = 4/250 (1%)
Query: 1 MGDWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPG 60
MGDW L +L++V HST+VGKIWLT+LFIFR+L+L +A E VW DEQS F CNT QPG
Sbjct: 1 MGDWNLLGGILEEVHSHSTIVGKIWLTILFIFRMLVLRVAAEDVWDDEQSAFACNTRQPG 60
Query: 61 CTNVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQ-KEGELRALPAK 119
C N+CYD AFPIS IR+WVLQ +FVS+P+LVY+GH +Y R E+ RQ K+ LRA +
Sbjct: 61 CNNICYDDAFPISLIRFWVLQIIFVSSPSLVYMGHALYRLRAFEKDRQRKKSHLRA-QME 119
Query: 120 DPQVE-RALAAVERQMAKISVAED-GRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLY 177
+P ++ ++R++ ++ + ++ ++G L+ TYV +L +SVLE GF+ GQ+ LY
Sbjct: 120 NPDLDLEEQQRIDRELRRLEEQKRIHKVPLKGCLLRTYVLHILTRSVLEVGFMIGQYILY 179
Query: 178 GWTMEPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCLS 237
G+ M P++ C + PCP VDCFVSRPTEKTIF++FM + ISL+LN+LE+ HL R +
Sbjct: 180 GFQMHPLYKCTQPPCPNAVDCFVSRPTEKTIFMLFMHSIAAISLLLNILEIFHLGIRKIM 239
Query: 238 RGMRARQGQD 247
R + + +
Sbjct: 240 RTLYKKSSSE 249
>gi|122939172 connexin 45 [Homo sapiens]
Length = 396
Score = 223 bits (569), Expect = 1e-58
Identities = 125/334 (37%), Positives = 184/334 (55%), Gaps = 29/334 (8%)
Query: 4 WGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPGCTN 63
W FL +LL+++ HST VGKIWLTVL +FRI++ + GES++ DEQS F CNT QPGC N
Sbjct: 3 WSFLTRLLEEIHNHSTFVGKIWLTVLIVFRIVLTAVGGESIYYDEQSKFVCNTEQPGCEN 62
Query: 64 VCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREER------------------ 105
VCYD P+SH+R+WV Q + V+TP+++YLG+ I+ + E
Sbjct: 63 VCYDAFAPLSHVRFWVFQIILVATPSVMYLGYAIHKIAKMEHGEADKKAARSKPYAMRWK 122
Query: 106 ----LRQKEGELRALPAKDPQVERALAAVERQMAKISVAEDGRLRIR-GALMGTYVASVL 160
L + E + P P++E ++ ++ DGR RIR LM YV +L
Sbjct: 123 QHRALEETEEDNEEDPMMYPEMELESDKENKEQSQPKPKHDGRRRIREDGLMKIYVLQLL 182
Query: 161 CKSVLEAGFLYGQWRLYGWTMEPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLIS 220
++V E GFL GQ+ LYG+ + P +VC R PCP+ +DCF+SRPTEKTIF++ M V +
Sbjct: 183 ARTVFEVGFLIGQYFLYGFQVHPFYVCSRLPCPHKIDCFISRPTEKTIFLLIMYGVTGLC 242
Query: 221 LVLNLLELVHLLCRCLSRGMRARQGQDAPPTQGTSSDPYTDQVFFYLPVGQGPSSPPCPT 280
L+LN+ E++HL + + +++ + P G + P+T P P
Sbjct: 243 LLLNIWEMLHLGFGTIRDSLNSKRRELEDP--GAYNYPFTWNTPSAPPGYNIAVKPDQIQ 300
Query: 281 YNGLSSS----EQNWANLTTEERLASSRPPLFLD 310
Y LS++ +QN AN E++ S L D
Sbjct: 301 YTELSNAKIAYKQNKANTAQEQQYGSHEENLPAD 334
>gi|69122473 connexin 45 [Homo sapiens]
Length = 396
Score = 223 bits (569), Expect = 1e-58
Identities = 125/334 (37%), Positives = 184/334 (55%), Gaps = 29/334 (8%)
Query: 4 WGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPGCTN 63
W FL +LL+++ HST VGKIWLTVL +FRI++ + GES++ DEQS F CNT QPGC N
Sbjct: 3 WSFLTRLLEEIHNHSTFVGKIWLTVLIVFRIVLTAVGGESIYYDEQSKFVCNTEQPGCEN 62
Query: 64 VCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREER------------------ 105
VCYD P+SH+R+WV Q + V+TP+++YLG+ I+ + E
Sbjct: 63 VCYDAFAPLSHVRFWVFQIILVATPSVMYLGYAIHKIAKMEHGEADKKAARSKPYAMRWK 122
Query: 106 ----LRQKEGELRALPAKDPQVERALAAVERQMAKISVAEDGRLRIR-GALMGTYVASVL 160
L + E + P P++E ++ ++ DGR RIR LM YV +L
Sbjct: 123 QHRALEETEEDNEEDPMMYPEMELESDKENKEQSQPKPKHDGRRRIREDGLMKIYVLQLL 182
Query: 161 CKSVLEAGFLYGQWRLYGWTMEPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLIS 220
++V E GFL GQ+ LYG+ + P +VC R PCP+ +DCF+SRPTEKTIF++ M V +
Sbjct: 183 ARTVFEVGFLIGQYFLYGFQVHPFYVCSRLPCPHKIDCFISRPTEKTIFLLIMYGVTGLC 242
Query: 221 LVLNLLELVHLLCRCLSRGMRARQGQDAPPTQGTSSDPYTDQVFFYLPVGQGPSSPPCPT 280
L+LN+ E++HL + + +++ + P G + P+T P P
Sbjct: 243 LLLNIWEMLHLGFGTIRDSLNSKRRELEDP--GAYNYPFTWNTPSAPPGYNIAVKPDQIQ 300
Query: 281 YNGLSSS----EQNWANLTTEERLASSRPPLFLD 310
Y LS++ +QN AN E++ S L D
Sbjct: 301 YTELSNAKIAYKQNKANTAQEQQYGSHEENLPAD 334
>gi|42558283 gap junction protein beta 2 [Homo sapiens]
Length = 226
Score = 220 bits (560), Expect = 2e-57
Identities = 112/236 (47%), Positives = 152/236 (64%), Gaps = 19/236 (8%)
Query: 3 DWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPGCT 62
DWG L+ +L V +HST +GKIWLTVLFIFRI+IL +A + VWGDEQ+DF CNT QPGC
Sbjct: 2 DWGTLQTILGGVNKHSTSIGKIWLTVLFIFRIMILVVAAKEVWGDEQADFVCNTLQPGCK 61
Query: 63 NVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKDPQ 122
NVCYD FPISHIR W LQ +FVSTP L+ HV Y R E++ + +GE+++
Sbjct: 62 NVCYDHYFPISHIRLWALQLIFVSTPALLVAMHVAY-RRHEKKRKFIKGEIKS------- 113
Query: 123 VERALAAVERQMAKISVAEDGRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLY-GWTM 181
+ I + ++RI G+L TY +S+ + + EA F+Y + +Y G++M
Sbjct: 114 ----------EFKDIEEIKTQKVRIEGSLWWTYTSSIFFRVIFEAAFMYVFYVMYDGFSM 163
Query: 182 EPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCLS 237
+ + C PCP VDCFVSRPTEKT+F +FM+ V I ++LN+ EL +LL R S
Sbjct: 164 QRLVKCNAWPCPNTVDCFVSRPTEKTVFTVFMIAVSGICILLNVTELCYLLIRYCS 219
>gi|45439367 gap junction protein, gamma 2, 47kDa [Homo sapiens]
Length = 439
Score = 217 bits (553), Expect = 1e-56
Identities = 141/399 (35%), Positives = 198/399 (49%), Gaps = 79/399 (19%)
Query: 4 WGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPGCTN 63
W FL +LL+++ HST VGK+WLTVL +FRI++ + GE+++ DEQ+ F CNT QPGC N
Sbjct: 6 WSFLTRLLEEIHNHSTFVGKVWLTVLVVFRIVLTAVGGEAIYSDEQAKFTCNTRQPGCDN 65
Query: 64 VCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIY-LSRREER-----LRQKEGELRA-- 115
VCYD P+SH+R+WV Q + +STP+++YLG+ ++ L+R E+ LR++ G RA
Sbjct: 66 VCYDAFAPLSHVRFWVFQIVVISTPSVMYLGYAVHRLARASEQERRRALRRRPGPRRAPR 125
Query: 116 ---------------LPAKDPQV-------------------ERALAAVERQMAKISVAE 141
L ++P + E A E K A+
Sbjct: 126 AHLPPPHAGWPEPADLGEEEPMLGLGEEEEEEETGAAEGAGEEAEEAGAEEACTKAVGAD 185
Query: 142 -------------DGRLRI-RGALMGTYVASVLCKSVLEAGFLYGQWRLYGWTMEPVFVC 187
DGR RI R LM YVA ++ ++ E FL GQ+ LYG+ + P F C
Sbjct: 186 GKAAGTPGPTGQHDGRRRIQREGLMRVYVAQLVARAAFEVAFLVGQYLLYGFEVRPFFPC 245
Query: 188 QRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCLSRGMRARQGQD 247
R PCP++VDCFVSRPTEKT+F++ M VV + L+LNL E+ HL +R R+G
Sbjct: 246 SRQPCPHVVDCFVSRPTEKTVFLLVMYVVSCLCLLLNLCEMAHLGLGSAQDAVRGRRG-- 303
Query: 248 APPTQGTSSDPYTDQVFFYLPVGQGPSSPP-----CPTYNGLSSSEQNWANLTTE----- 297
PP + P F G + PP + +QN ANL +
Sbjct: 304 -PPASAPAPAPRPPPCAF-PAAAAGLACPPDYSLVVRAAERARAHDQNLANLALQALRDG 361
Query: 298 ----ERLASSRP----PLFLDPPPQNGQKPPSRPSSSAS 328
+R S P P PP+ G P SR S+ S
Sbjct: 362 AAAGDRDRDSSPCVGLPAASRGPPRAG-APASRTGSATS 399
>gi|159032020 gap junction protein, beta 6 [Homo sapiens]
Length = 261
Score = 215 bits (548), Expect = 4e-56
Identities = 111/249 (44%), Positives = 150/249 (60%), Gaps = 20/249 (8%)
Query: 3 DWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPGCT 62
DWG L + V +HST +GK+W+TV+FIFR++IL +A + VWGDEQ DF CNT QPGC
Sbjct: 2 DWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGCK 61
Query: 63 NVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKDPQ 122
NVCYD FP+SHIR W LQ +FVSTP L+ HV Y R E + + GE R
Sbjct: 62 NVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYY-RHETTRKFRRGEKR-------- 112
Query: 123 VERALAAVERQMAKISVAEDGRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLY-GWTM 181
I + ++RI G+L TY +S+ + + EA F+Y + LY G+ +
Sbjct: 113 ---------NDFKDIEDIKKQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHL 163
Query: 182 EPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCR-CLSRGM 240
V C PCP LVDCF+SRPTEKT+F IFM+ +I ++LN+ EL +LL + C R
Sbjct: 164 PWVLKCGIDPCPNLVDCFISRPTEKTVFTIFMISASVICMLLNVAELCYLLLKVCFRRSK 223
Query: 241 RARQGQDAP 249
RA+ ++ P
Sbjct: 224 RAQTQKNHP 232
>gi|158966714 gap junction protein, beta 6 [Homo sapiens]
Length = 261
Score = 215 bits (548), Expect = 4e-56
Identities = 111/249 (44%), Positives = 150/249 (60%), Gaps = 20/249 (8%)
Query: 3 DWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPGCT 62
DWG L + V +HST +GK+W+TV+FIFR++IL +A + VWGDEQ DF CNT QPGC
Sbjct: 2 DWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGCK 61
Query: 63 NVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKDPQ 122
NVCYD FP+SHIR W LQ +FVSTP L+ HV Y R E + + GE R
Sbjct: 62 NVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYY-RHETTRKFRRGEKR-------- 112
Query: 123 VERALAAVERQMAKISVAEDGRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLY-GWTM 181
I + ++RI G+L TY +S+ + + EA F+Y + LY G+ +
Sbjct: 113 ---------NDFKDIEDIKKQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHL 163
Query: 182 EPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCR-CLSRGM 240
V C PCP LVDCF+SRPTEKT+F IFM+ +I ++LN+ EL +LL + C R
Sbjct: 164 PWVLKCGIDPCPNLVDCFISRPTEKTVFTIFMISASVICMLLNVAELCYLLLKVCFRRSK 223
Query: 241 RARQGQDAP 249
RA+ ++ P
Sbjct: 224 RAQTQKNHP 232
>gi|158966717 gap junction protein, beta 6 [Homo sapiens]
Length = 261
Score = 215 bits (548), Expect = 4e-56
Identities = 111/249 (44%), Positives = 150/249 (60%), Gaps = 20/249 (8%)
Query: 3 DWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPGCT 62
DWG L + V +HST +GK+W+TV+FIFR++IL +A + VWGDEQ DF CNT QPGC
Sbjct: 2 DWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGCK 61
Query: 63 NVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKDPQ 122
NVCYD FP+SHIR W LQ +FVSTP L+ HV Y R E + + GE R
Sbjct: 62 NVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYY-RHETTRKFRRGEKR-------- 112
Query: 123 VERALAAVERQMAKISVAEDGRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLY-GWTM 181
I + ++RI G+L TY +S+ + + EA F+Y + LY G+ +
Sbjct: 113 ---------NDFKDIEDIKKQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHL 163
Query: 182 EPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCR-CLSRGM 240
V C PCP LVDCF+SRPTEKT+F IFM+ +I ++LN+ EL +LL + C R
Sbjct: 164 PWVLKCGIDPCPNLVDCFISRPTEKTVFTIFMISASVICMLLNVAELCYLLLKVCFRRSK 223
Query: 241 RARQGQDAP 249
RA+ ++ P
Sbjct: 224 RAQTQKNHP 232
>gi|40254837 gap junction protein, beta 6 [Homo sapiens]
Length = 261
Score = 215 bits (548), Expect = 4e-56
Identities = 111/249 (44%), Positives = 150/249 (60%), Gaps = 20/249 (8%)
Query: 3 DWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPGCT 62
DWG L + V +HST +GK+W+TV+FIFR++IL +A + VWGDEQ DF CNT QPGC
Sbjct: 2 DWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGCK 61
Query: 63 NVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKDPQ 122
NVCYD FP+SHIR W LQ +FVSTP L+ HV Y R E + + GE R
Sbjct: 62 NVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYY-RHETTRKFRRGEKR-------- 112
Query: 123 VERALAAVERQMAKISVAEDGRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLY-GWTM 181
I + ++RI G+L TY +S+ + + EA F+Y + LY G+ +
Sbjct: 113 ---------NDFKDIEDIKKQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHL 163
Query: 182 EPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCR-CLSRGM 240
V C PCP LVDCF+SRPTEKT+F IFM+ +I ++LN+ EL +LL + C R
Sbjct: 164 PWVLKCGIDPCPNLVDCFISRPTEKTVFTIFMISASVICMLLNVAELCYLLLKVCFRRSK 223
Query: 241 RARQGQDAP 249
RA+ ++ P
Sbjct: 224 RAQTQKNHP 232
>gi|148233402 gap junction protein, beta 1, 32kDa [Homo sapiens]
Length = 283
Score = 206 bits (523), Expect = 3e-53
Identities = 112/253 (44%), Positives = 155/253 (61%), Gaps = 22/253 (8%)
Query: 3 DWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPGCT 62
+W L LL V HST +G++WL+V+FIFRI++L +A ESVWGDE+S F CNT QPGC
Sbjct: 2 NWTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGCN 61
Query: 63 NVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKDPQ 122
+VCYDQ FPISH+R W LQ + VSTP L+ HV + E+++ + EG DP
Sbjct: 62 SVCYDQFFPISHVRLWSLQLILVSTPALLVAMHVAHQQHIEKKMLRLEGH------GDP- 114
Query: 123 VERALAAVERQMAKISVAEDGRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLY-GWTM 181
L V+R ++ I G L TYV SV+ + + EA F+Y + LY G+ M
Sbjct: 115 --LHLEEVKRH----------KVHISGTLWWTYVISVVFRLLFEAVFMYVFYLLYPGYAM 162
Query: 182 EPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCLSRGMR 241
+ C PCP VDCFVSRPTEKT+F +FML I ++LN+ E+V+L+ R +R R
Sbjct: 163 VRLVKCDVYPCPNTVDCFVSRPTEKTVFTVFMLAASGICIILNVAEVVYLIIRACAR--R 220
Query: 242 ARQGQDAPPTQGT 254
A++ + P +G+
Sbjct: 221 AQRRSNPPSRKGS 233
>gi|4504005 gap junction protein, beta 1, 32kDa [Homo sapiens]
Length = 283
Score = 206 bits (523), Expect = 3e-53
Identities = 112/253 (44%), Positives = 155/253 (61%), Gaps = 22/253 (8%)
Query: 3 DWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPGCT 62
+W L LL V HST +G++WL+V+FIFRI++L +A ESVWGDE+S F CNT QPGC
Sbjct: 2 NWTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGCN 61
Query: 63 NVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKDPQ 122
+VCYDQ FPISH+R W LQ + VSTP L+ HV + E+++ + EG DP
Sbjct: 62 SVCYDQFFPISHVRLWSLQLILVSTPALLVAMHVAHQQHIEKKMLRLEGH------GDP- 114
Query: 123 VERALAAVERQMAKISVAEDGRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLY-GWTM 181
L V+R ++ I G L TYV SV+ + + EA F+Y + LY G+ M
Sbjct: 115 --LHLEEVKRH----------KVHISGTLWWTYVISVVFRLLFEAVFMYVFYLLYPGYAM 162
Query: 182 EPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCLSRGMR 241
+ C PCP VDCFVSRPTEKT+F +FML I ++LN+ E+V+L+ R +R R
Sbjct: 163 VRLVKCDVYPCPNTVDCFVSRPTEKTVFTVFMLAASGICIILNVAEVVYLIIRACAR--R 220
Query: 242 ARQGQDAPPTQGT 254
A++ + P +G+
Sbjct: 221 AQRRSNPPSRKGS 233
>gi|54607056 connexin 31 [Homo sapiens]
Length = 270
Score = 199 bits (507), Expect = 2e-51
Identities = 105/240 (43%), Positives = 145/240 (60%), Gaps = 25/240 (10%)
Query: 3 DWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPGCT 62
DW L+ LL V ++ST G+IWL+V+F+FR+L+ +A E VWGDEQ DF+CNT QPGCT
Sbjct: 2 DWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGCT 61
Query: 63 NVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKDPQ 122
NVCYD FPIS+IR W LQ +FV+ P+L+ + HV Y RE R RQK G+
Sbjct: 62 NVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYREERERRHRQKHGD---------- 111
Query: 123 VERALAAVERQMAKISVAEDGRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRL-YGWTM 181
Q AK+ D + G L TY+ S++ K ++E FLY L +G+ M
Sbjct: 112 ----------QCAKL---YDNAGKKHGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNM 158
Query: 182 EPVFVCQR-APCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCLSRGM 240
+ C APCP +VDC+++RPTEK IF FM+ + +VL + EL +L+C + RG+
Sbjct: 159 PRLVQCANVAPCPNIVDCYIARPTEKKIFTYFMVGASAVCIVLTICELCYLICHRVLRGL 218
>gi|13128960 connexin 31 [Homo sapiens]
Length = 270
Score = 199 bits (507), Expect = 2e-51
Identities = 105/240 (43%), Positives = 145/240 (60%), Gaps = 25/240 (10%)
Query: 3 DWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPGCT 62
DW L+ LL V ++ST G+IWL+V+F+FR+L+ +A E VWGDEQ DF+CNT QPGCT
Sbjct: 2 DWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGCT 61
Query: 63 NVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKDPQ 122
NVCYD FPIS+IR W LQ +FV+ P+L+ + HV Y RE R RQK G+
Sbjct: 62 NVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYREERERRHRQKHGD---------- 111
Query: 123 VERALAAVERQMAKISVAEDGRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRL-YGWTM 181
Q AK+ D + G L TY+ S++ K ++E FLY L +G+ M
Sbjct: 112 ----------QCAKL---YDNAGKKHGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNM 158
Query: 182 EPVFVCQR-APCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCLSRGM 240
+ C APCP +VDC+++RPTEK IF FM+ + +VL + EL +L+C + RG+
Sbjct: 159 PRLVQCANVAPCPNIVDCYIARPTEKKIFTYFMVGASAVCIVLTICELCYLICHRVLRGL 218
>gi|23397464 gap junction protein, beta 4 [Homo sapiens]
Length = 266
Score = 194 bits (492), Expect = 1e-49
Identities = 99/236 (41%), Positives = 138/236 (58%), Gaps = 25/236 (10%)
Query: 3 DWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPGCT 62
+W FL+ LL V ++STV+ +IWL+V+FIFR+L+ +A E VW DEQ DF CNT QPGC
Sbjct: 2 NWAFLQGLLSGVNKYSTVLSRIWLSVVFIFRVLVYVVAAEEVWDDEQKDFVCNTKQPGCP 61
Query: 63 NVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKDPQ 122
NVCYD+ FP+SH+R W LQ + V+ P+L+ + HV Y RE + K G
Sbjct: 62 NVCYDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYREERERKHHLKHGP---------- 111
Query: 123 VERALAAVERQMAKISVAEDGRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLY-GWTM 181
D + RG L TY+ S++ K+ ++AGFLY RLY + M
Sbjct: 112 -------------NAPSLYDNLSKKRGGLWWTYLLSLIFKAAVDAGFLYIFHRLYKDYDM 158
Query: 182 EPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLL-CRCL 236
V C PCP+ VDC++SRPTEK +F FM+ I ++LNL E+ +L+ RC+
Sbjct: 159 PRVVACSVEPCPHTVDCYISRPTEKKVFTYFMVTTAAICILLNLSEVFYLVGKRCM 214
>gi|10190698 gap junction protein, delta 2, 36kDa [Homo sapiens]
Length = 321
Score = 192 bits (487), Expect = 5e-49
Identities = 109/290 (37%), Positives = 160/290 (55%), Gaps = 44/290 (15%)
Query: 1 MGDWGFLEKLLDQ-VQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQP 59
MG+W LE+LL+ VQ+HST++G+I LTV+ IFRILI+ + GE+V+ DEQ+ F CNT QP
Sbjct: 1 MGEWTILERLLEAAVQQHSTMIGRILLTVVVIFRILIVAIVGETVYDDEQTMFVCNTLQP 60
Query: 60 GCTNVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLS------------------- 100
GC CYD+AFPISHIRYWV Q + V TP+L ++ + ++ S
Sbjct: 61 GCNQACYDRAFPISHIRYWVFQIIMVCTPSLCFITYSVHQSAKQRERRYSTVFLALDRDP 120
Query: 101 ------------------RREERLRQK---EGELRALPAKDPQVERALAAVER---QMAK 136
+RE++ Q G L+ + E V+ +
Sbjct: 121 PESIGGPGGTGGGGSGGGKREDKKLQNAIVNGVLQNTENTSKETEPDCLEVKELTPHPSG 180
Query: 137 ISVAEDGRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLYGWTMEPVFVCQRAPCPYLV 196
+ A +LR + + Y+ V+ ++ LE GFL GQ+ LYG+++ ++ C R PC V
Sbjct: 181 LRTASKSKLRRQEGISRFYIIQVVFRNALEIGFLVGQYFLYGFSVPGLYECNRYPCIKEV 240
Query: 197 DCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCLSRGMRARQGQ 246
+C+VSRPTEKT+F++FM V I +VLNL EL HL R + +R Q +
Sbjct: 241 ECYVSRPTEKTVFLVFMFAVSGICVVLNLAELNHLGWRKIKLAVRGAQAK 290
>gi|10835079 gap junction protein, beta 5, 31.1kDa [Homo sapiens]
Length = 273
Score = 189 bits (480), Expect = 3e-48
Identities = 95/250 (38%), Positives = 143/250 (57%), Gaps = 34/250 (13%)
Query: 3 DWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPGCT 62
+W E LL V ++ST G+IWL+++FIFR+L+ + E VW D+ DF+CNT QPGC+
Sbjct: 2 NWSIFEGLLSGVNKYSTAFGRIWLSLVFIFRVLVYLVTAERVWSDDHKDFDCNTRQPGCS 61
Query: 63 NVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKDPQ 122
NVC+D+ FP+SH+R W LQ + V+ P+L+ + HV Y +E+R R+ GE
Sbjct: 62 NVCFDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYREVQEKRHREAHGE---------- 111
Query: 123 VERALAAVERQMAKISVAEDGRLRI-----RGALMGTYVASVLCKSVLEAGFLYGQWRLY 177
GRL + RG L TYV S++ K+ ++ FLY Y
Sbjct: 112 ------------------NSGRLYLNPGKKRGGLWWTYVCSLVFKASVDIAFLYVFHSFY 153
Query: 178 -GWTMEPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCL 236
+ + PV C PCP +VDCF+S+P+EK IF +FM+ I ++LNL+EL++L+ +
Sbjct: 154 PKYILPPVVKCHADPCPNIVDCFISKPSEKNIFTLFMVATAAICILLNLVELIYLVSKRC 213
Query: 237 SRGMRARQGQ 246
+ AR+ Q
Sbjct: 214 HECLAARKAQ 223
>gi|148839378 gap junction protein, delta 3, 31.9kDa [Homo sapiens]
Length = 294
Score = 187 bits (475), Expect = 1e-47
Identities = 97/232 (41%), Positives = 136/232 (58%), Gaps = 19/232 (8%)
Query: 1 MGDWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPG 60
MG+W FL LLD VQ S +VG++WL V+ IFRIL+L G +V+ DEQ +F CNT QPG
Sbjct: 1 MGEWAFLGSLLDAVQLQSPLVGRLWLVVMLIFRILVLATVGGAVFEDEQEEFVCNTLQPG 60
Query: 61 CTNVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKD 120
C CYD+AFP+SH R+W+ L +S P ++++ V + R + E + P
Sbjct: 61 CRQTCYDRAFPVSHYRFWLFHILLLSAPPVLFV--VYSMHRAGKEAGGAEAAAQCAPGL- 117
Query: 121 PQVERALAAVERQMAKISVAEDGRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLYGWT 180
P+ + A A+ + A+ Y+ SV + + E FL GQ LYG+
Sbjct: 118 PEAQCAPCALRARRAR----------------RCYLLSVALRLLAELTFLGGQALLYGFR 161
Query: 181 MEPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLL 232
+ P F C PCP+ VDCFVSRPTEKT+F++F VGL+S +L++ EL HLL
Sbjct: 162 VAPHFACAGPPCPHTVDCFVSRPTEKTVFVLFYFAVGLLSALLSVAELGHLL 213
>gi|38348412 gap junction protein, beta 7, 25kDa [Homo sapiens]
Length = 223
Score = 182 bits (463), Expect = 3e-46
Identities = 96/233 (41%), Positives = 135/233 (57%), Gaps = 31/233 (13%)
Query: 4 WGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPGCTN 63
W FL LL V ++ST G IWL V+F+FR+L+ +A E VW DEQ +FECN+ QPGC N
Sbjct: 3 WMFLRDLLSGVNKYSTGTGWIWLAVVFVFRLLVYMVAAEHVWKDEQKEFECNSRQPGCKN 62
Query: 64 VCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKDPQV 123
VC+D FPIS +R W LQ + VSTP+L+ + HV Y RE+R R+K L P
Sbjct: 63 VCFDDFFPISQVRLWALQLIMVSTPSLLVVLHVAYHEGREKRHRKK---LYVSPG----- 114
Query: 124 ERALAAVERQMAKISVAEDGRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLY-GWTME 182
+ G L Y+ S++ K+ E GFL ++LY G+++
Sbjct: 115 ----------------------TMDGGLWYAYLISLIVKTGFEIGFLVLFYKLYDGFSVP 152
Query: 183 PVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRC 235
+ C PCP VDCF+S+PTEKTIFI+F+++ + +VLN +EL L+ +C
Sbjct: 153 YLIKCDLKPCPNTVDCFISKPTEKTIFILFLVITSCLCIVLNFIELSFLVLKC 205
>gi|145699105 connexin40.1 [Homo sapiens]
Length = 370
Score = 145 bits (367), Expect = 4e-35
Identities = 87/233 (37%), Positives = 132/233 (56%), Gaps = 19/233 (8%)
Query: 19 TVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPGCTNVCYDQAFPISHIRYW 78
T+VGK+W + + R+L++ LAG V+ DEQ F CNT QPGC NVCYD P+SH+R+W
Sbjct: 19 TMVGKLWFVLTMLLRMLVIVLAGRPVYQDEQERFVCNTLQPGCANVCYDVFSPVSHLRFW 78
Query: 79 VLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKDPQVERALAAVERQMAKIS 138
++Q + V P+ V+ +V++ + L AL + R A+ +R+ +
Sbjct: 79 LIQGVCVLLPSAVFSVYVLH----------RGATLAALGPRRCPDPREPASGQRRCPR-P 127
Query: 139 VAEDGRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLYGWTMEPVFVCQRAPCPYLVDC 198
E G L++ G Y+ +L +++LEA F + L+G+ F C R PC +VDC
Sbjct: 128 FGERGGLQVPDFSAG-YIIHLLLRTLLEAAFGALHYFLFGFLAPKKFPCTRPPCTGVVDC 186
Query: 199 FVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCLSRGMRARQGQDAPPT 251
+VSRPTEK++ ++F+ V +S +L L +LV C L R MR R G PPT
Sbjct: 187 YVSRPTEKSLLMLFLWAVSALSFLLGLADLV---C-SLRRRMRRRPG---PPT 232
>gi|31559821 gap junction protein, gamma 3, 30.2kDa [Homo sapiens]
Length = 279
Score = 141 bits (355), Expect = 9e-34
Identities = 84/226 (37%), Positives = 119/226 (52%), Gaps = 17/226 (7%)
Query: 6 FLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPGCTNVC 65
FL +LL + ST VG++ L VL FR+++L +G V+GDEQS+F C+T QPGC C
Sbjct: 5 FLRRLLAEESRRSTPVGRLLLPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAAC 64
Query: 66 YDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKDPQVER 125
+D P+S +R+WV Q + V+ P+ +Y+G +Y L K E L
Sbjct: 65 FDAFHPLSPLRFWVFQVILVAVPSALYMGFTLYHVIWHWELSGKGKEEETL--------- 115
Query: 126 ALAAVERQMAKISVAEDGRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLYGWTMEPVF 185
++ + V G LR L+ YVA + + VLE L Q+ LYG+ M F
Sbjct: 116 ----IQGREGNTDVPGAGSLR----LLWAYVAQLGARLVLEGAALGLQYHLYGFQMPSSF 167
Query: 186 VCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHL 231
C+R PC + C +SRP+EKTIF+ M V L+ LELV L
Sbjct: 168 ACRREPCLGSITCNLSRPSEKTIFLKTMFGVSGFCLLFTFLELVLL 213
>gi|169171704 PREDICTED: similar to hCG1770601 [Homo sapiens]
Length = 222
Score = 90.1 bits (222), Expect = 2e-18
Identities = 38/86 (44%), Positives = 59/86 (68%)
Query: 10 LLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPGCTNVCYDQA 69
LL + HST VG++ VL FR+++L +G V+GDEQS+F C+T QPGC C+D
Sbjct: 28 LLAEESWHSTPVGRLLFPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACFDAF 87
Query: 70 FPISHIRYWVLQFLFVSTPTLVYLGH 95
P+S +R+WV Q + V+ P+++Y+G+
Sbjct: 88 HPLSPLRFWVFQVILVAVPSVLYMGY 113
>gi|169171845 PREDICTED: similar to hCG1770601 [Homo sapiens]
Length = 222
Score = 90.1 bits (222), Expect = 2e-18
Identities = 38/86 (44%), Positives = 59/86 (68%)
Query: 10 LLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPGCTNVCYDQA 69
LL + HST VG++ VL FR+++L +G V+GDEQS+F C+T QPGC C+D
Sbjct: 28 LLAEESWHSTPVGRLLFPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACFDAF 87
Query: 70 FPISHIRYWVLQFLFVSTPTLVYLGH 95
P+S +R+WV Q + V+ P+++Y+G+
Sbjct: 88 HPLSPLRFWVFQVILVAVPSVLYMGY 113
>gi|169171183 PREDICTED: similar to hCG1770601 [Homo sapiens]
Length = 222
Score = 90.1 bits (222), Expect = 2e-18
Identities = 38/86 (44%), Positives = 59/86 (68%)
Query: 10 LLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPGCTNVCYDQA 69
LL + HST VG++ VL FR+++L +G V+GDEQS+F C+T QPGC C+D
Sbjct: 28 LLAEESWHSTPVGRLLFPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACFDAF 87
Query: 70 FPISHIRYWVLQFLFVSTPTLVYLGH 95
P+S +R+WV Q + V+ P+++Y+G+
Sbjct: 88 HPLSPLRFWVFQVILVAVPSVLYMGY 113
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.138 0.436
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,413,890
Number of Sequences: 37866
Number of extensions: 689360
Number of successful extensions: 3209
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 43
Number of HSP's successfully gapped in prelim test: 33
Number of HSP's that attempted gapping in prelim test: 3084
Number of HSP's gapped (non-prelim): 122
length of query: 333
length of database: 18,247,518
effective HSP length: 103
effective length of query: 230
effective length of database: 14,347,320
effective search space: 3299883600
effective search space used: 3299883600
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.