BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|62865631 solute carrier family 27 (fatty acid transporter), member 6 [Homo sapiens] (619 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|62865631 solute carrier family 27 (fatty acid transporter), m... 1255 0.0 gi|13325055 solute carrier family 27 (fatty acid transporter), m... 1255 0.0 gi|227499619 solute carrier family 27 (fatty acid transporter), ... 648 0.0 gi|227499621 solute carrier family 27 (fatty acid transporter), ... 571 e-163 gi|13236579 solute carrier family 27 member 3 [Homo sapiens] 518 e-147 gi|13325057 solute carrier family 27 (fatty acid transporter), m... 497 e-140 gi|40807357 solute carrier family 27 (fatty acid transporter), m... 422 e-118 gi|38524616 solute carrier family 27, member 1 [Homo sapiens] 410 e-114 gi|28416953 acyl-CoA synthetase short-chain family member 1 [Hom... 69 1e-11 gi|42544132 SA hypertension-associated homolog isoform 1 [Homo s... 67 5e-11 gi|122937307 acyl-CoA synthetase medium-chain family member 4 [H... 64 3e-10 gi|157311624 acyl-CoA synthetase medium-chain family member 2B [... 64 4e-10 gi|157311622 acyl-CoA synthetase medium-chain family member 2B [... 64 4e-10 gi|38505220 acyl-CoA synthetase medium-chain family member 5 [Ho... 62 2e-09 gi|115511026 acyl-CoA synthetase medium-chain family member 1 [H... 62 2e-09 gi|239756507 PREDICTED: similar to Acyl-coenzyme A synthetase AC... 61 3e-09 gi|239756505 PREDICTED: similar to Acyl-coenzyme A synthetase AC... 61 3e-09 gi|58082049 acyl-CoA synthetase medium-chain family member 2A [H... 60 6e-09 gi|187761345 acyl-CoA synthetase family member 3 [Homo sapiens] 60 8e-09 gi|187761343 acyl-CoA synthetase family member 3 [Homo sapiens] 60 8e-09 gi|13375727 acyl-CoA synthetase short-chain family member 3 [Hom... 58 3e-08 gi|42544134 SA hypertension-associated homolog isoform 2 [Homo s... 54 6e-07 gi|8923896 acyl-CoA synthetase short-chain family member 2 isofo... 50 6e-06 gi|253970489 acyl-CoA synthetase short-chain family member 2 iso... 45 2e-04 gi|156151445 acyl-CoA synthetase family member 2 [Homo sapiens] 42 0.001 gi|195947378 acyl-coenzyme A synthetase ACSM6, mitochondrial [Ho... 42 0.002 gi|27477105 lipidosin [Homo sapiens] 40 0.006 gi|42794760 acyl-CoA synthetase long-chain family member 5 isofo... 37 0.041 gi|42794758 acyl-CoA synthetase long-chain family member 5 isofo... 37 0.041 gi|42794756 acyl-CoA synthetase long-chain family member 5 isofo... 37 0.041 >gi|62865631 solute carrier family 27 (fatty acid transporter), member 6 [Homo sapiens] Length = 619 Score = 1255 bits (3247), Expect = 0.0 Identities = 619/619 (100%), Positives = 619/619 (100%) Query: 1 MLLSWLTVLGAGMVVLHFLQKLLFPYFWDDFWFVLKVVLIIIRLKKYEKRGELVTVLDKF 60 MLLSWLTVLGAGMVVLHFLQKLLFPYFWDDFWFVLKVVLIIIRLKKYEKRGELVTVLDKF Sbjct: 1 MLLSWLTVLGAGMVVLHFLQKLLFPYFWDDFWFVLKVVLIIIRLKKYEKRGELVTVLDKF 60 Query: 61 LSHAKRQPRKPFIIYEGDIYTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVH 120 LSHAKRQPRKPFIIYEGDIYTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVH Sbjct: 61 LSHAKRQPRKPFIIYEGDIYTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVH 120 Query: 121 VWFGLAKLGCVVAFLNTNIRSNSLLNCIRACGPRALVVGADLLGTVEEILPSLSENISVW 180 VWFGLAKLGCVVAFLNTNIRSNSLLNCIRACGPRALVVGADLLGTVEEILPSLSENISVW Sbjct: 121 VWFGLAKLGCVVAFLNTNIRSNSLLNCIRACGPRALVVGADLLGTVEEILPSLSENISVW 180 Query: 181 GMKDSVPQGVISLKEKLSTSPDEPVPRSHHVVSLLKSTCLYIFTSGTTGLPKAAVISQLQ 240 GMKDSVPQGVISLKEKLSTSPDEPVPRSHHVVSLLKSTCLYIFTSGTTGLPKAAVISQLQ Sbjct: 181 GMKDSVPQGVISLKEKLSTSPDEPVPRSHHVVSLLKSTCLYIFTSGTTGLPKAAVISQLQ 240 Query: 241 VLRGSAVLWAFGCTAHDIVYITLPLYHSSAAILGISGCVELGATCVLKKKFSASQFWSDC 300 VLRGSAVLWAFGCTAHDIVYITLPLYHSSAAILGISGCVELGATCVLKKKFSASQFWSDC Sbjct: 241 VLRGSAVLWAFGCTAHDIVYITLPLYHSSAAILGISGCVELGATCVLKKKFSASQFWSDC 300 Query: 301 KKYDVTVFQYIGELCRYLCKQSKREGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVCEL 360 KKYDVTVFQYIGELCRYLCKQSKREGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVCEL Sbjct: 301 KKYDVTVFQYIGELCRYLCKQSKREGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVCEL 360 Query: 361 YAATESSISFMNYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGE 420 YAATESSISFMNYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGE Sbjct: 361 YAATESSISFMNYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGE 420 Query: 421 PGLLISRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRT 480 PGLLISRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRT Sbjct: 421 PGLLISRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRT 480 Query: 481 GDTFRWKGENVATTEVADVIGMLDFIQEANVYGVAISGYEGRAGMASIILKPNTSLDLEK 540 GDTFRWKGENVATTEVADVIGMLDFIQEANVYGVAISGYEGRAGMASIILKPNTSLDLEK Sbjct: 481 GDTFRWKGENVATTEVADVIGMLDFIQEANVYGVAISGYEGRAGMASIILKPNTSLDLEK 540 Query: 541 VYEQVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQLVEDGFNPLKISEPLYFMDNLKKS 600 VYEQVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQLVEDGFNPLKISEPLYFMDNLKKS Sbjct: 541 VYEQVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQLVEDGFNPLKISEPLYFMDNLKKS 600 Query: 601 YVLLTRELYDQIMLGEIKL 619 YVLLTRELYDQIMLGEIKL Sbjct: 601 YVLLTRELYDQIMLGEIKL 619 >gi|13325055 solute carrier family 27 (fatty acid transporter), member 6 [Homo sapiens] Length = 619 Score = 1255 bits (3247), Expect = 0.0 Identities = 619/619 (100%), Positives = 619/619 (100%) Query: 1 MLLSWLTVLGAGMVVLHFLQKLLFPYFWDDFWFVLKVVLIIIRLKKYEKRGELVTVLDKF 60 MLLSWLTVLGAGMVVLHFLQKLLFPYFWDDFWFVLKVVLIIIRLKKYEKRGELVTVLDKF Sbjct: 1 MLLSWLTVLGAGMVVLHFLQKLLFPYFWDDFWFVLKVVLIIIRLKKYEKRGELVTVLDKF 60 Query: 61 LSHAKRQPRKPFIIYEGDIYTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVH 120 LSHAKRQPRKPFIIYEGDIYTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVH Sbjct: 61 LSHAKRQPRKPFIIYEGDIYTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVH 120 Query: 121 VWFGLAKLGCVVAFLNTNIRSNSLLNCIRACGPRALVVGADLLGTVEEILPSLSENISVW 180 VWFGLAKLGCVVAFLNTNIRSNSLLNCIRACGPRALVVGADLLGTVEEILPSLSENISVW Sbjct: 121 VWFGLAKLGCVVAFLNTNIRSNSLLNCIRACGPRALVVGADLLGTVEEILPSLSENISVW 180 Query: 181 GMKDSVPQGVISLKEKLSTSPDEPVPRSHHVVSLLKSTCLYIFTSGTTGLPKAAVISQLQ 240 GMKDSVPQGVISLKEKLSTSPDEPVPRSHHVVSLLKSTCLYIFTSGTTGLPKAAVISQLQ Sbjct: 181 GMKDSVPQGVISLKEKLSTSPDEPVPRSHHVVSLLKSTCLYIFTSGTTGLPKAAVISQLQ 240 Query: 241 VLRGSAVLWAFGCTAHDIVYITLPLYHSSAAILGISGCVELGATCVLKKKFSASQFWSDC 300 VLRGSAVLWAFGCTAHDIVYITLPLYHSSAAILGISGCVELGATCVLKKKFSASQFWSDC Sbjct: 241 VLRGSAVLWAFGCTAHDIVYITLPLYHSSAAILGISGCVELGATCVLKKKFSASQFWSDC 300 Query: 301 KKYDVTVFQYIGELCRYLCKQSKREGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVCEL 360 KKYDVTVFQYIGELCRYLCKQSKREGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVCEL Sbjct: 301 KKYDVTVFQYIGELCRYLCKQSKREGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVCEL 360 Query: 361 YAATESSISFMNYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGE 420 YAATESSISFMNYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGE Sbjct: 361 YAATESSISFMNYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGE 420 Query: 421 PGLLISRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRT 480 PGLLISRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRT Sbjct: 421 PGLLISRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRT 480 Query: 481 GDTFRWKGENVATTEVADVIGMLDFIQEANVYGVAISGYEGRAGMASIILKPNTSLDLEK 540 GDTFRWKGENVATTEVADVIGMLDFIQEANVYGVAISGYEGRAGMASIILKPNTSLDLEK Sbjct: 481 GDTFRWKGENVATTEVADVIGMLDFIQEANVYGVAISGYEGRAGMASIILKPNTSLDLEK 540 Query: 541 VYEQVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQLVEDGFNPLKISEPLYFMDNLKKS 600 VYEQVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQLVEDGFNPLKISEPLYFMDNLKKS Sbjct: 541 VYEQVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQLVEDGFNPLKISEPLYFMDNLKKS 600 Query: 601 YVLLTRELYDQIMLGEIKL 619 YVLLTRELYDQIMLGEIKL Sbjct: 601 YVLLTRELYDQIMLGEIKL 619 >gi|227499619 solute carrier family 27 (fatty acid transporter), member 2 isoform 1 [Homo sapiens] Length = 620 Score = 648 bits (1672), Expect = 0.0 Identities = 316/621 (50%), Positives = 431/621 (69%), Gaps = 3/621 (0%) Query: 1 MLLSWLTVLGAGMVVLHFLQKLLFPYFWDDFWFVLKVVLIIIRLKKYEKRGELVTVLDKF 60 ML + TVL AG++ L L L PYF+ D + LKV + R++ Y KR T+L F Sbjct: 1 MLSAIYTVL-AGLLFLPLLVNLCCPYFFQDIGYFLKVAAVGRRVRSYGKRRPARTILRAF 59 Query: 61 LSHAKRQPRKPFIIYEGDIYTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVH 120 L A++ P KPF+++ + TY VD+RS++VA +H L++GD VALLM NEP +V Sbjct: 60 LEKARQTPHKPFLLFRDETLTYAQVDRRSNQVARALHDHLGLRQGDCVALLMGNEPAYVW 119 Query: 121 VWFGLAKLGCVVAFLNTNIRSNSLLNCIRACGPRALVVGADLLGTVEEILPSLS-ENISV 179 +W GL KLGC +A LN NIR+ SLL+C + CG + L+V +L VEEILPSL +++S+ Sbjct: 120 LWLGLVKLGCAMACLNYNIRAKSLLHCFQCCGAKVLLVSPELQAAVEEILPSLKKDDVSI 179 Query: 180 WGM-KDSVPQGVISLKEKLSTSPDEPVPRSHHVVSLLKSTCLYIFTSGTTGLPKAAVISQ 238 + + + S G+ S +K+ EP+P S + LYI+TSGTTGLPKAA+I+ Sbjct: 180 YYVSRTSNTDGIDSFLDKVDEVSTEPIPESWRSEVTFSTPALYIYTSGTTGLPKAAMITH 239 Query: 239 LQVLRGSAVLWAFGCTAHDIVYITLPLYHSSAAILGISGCVELGATCVLKKKFSASQFWS 298 ++ G+ + + G A D++YITLP YHS+A ++GI GC+ GAT L+ KFSASQFW Sbjct: 240 QRIWYGTGLTFVSGLKADDVIYITLPFYHSAALLIGIHGCIVAGATLALRTKFSASQFWD 299 Query: 299 DCKKYDVTVFQYIGELCRYLCKQSKREGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVC 358 DC+KY+VTV QYIGEL RYLC ++ ++DHKVRLA+GNG+R DVWR+F+ RFG+I + Sbjct: 300 DCRKYNVTVIQYIGELLRYLCNSPQKPNDRDHKVRLALGNGLRGDVWRQFVKRFGDICIY 359 Query: 359 ELYAATESSISFMNYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKK 418 E YAATE +I FMNY ++GA+GR N K + T+DLIKYD +KDEP+R+E G+C+ V K Sbjct: 360 EFYAATEGNIGFMNYARKVGAVGRVNYLQKKIITYDLIKYDVEKDEPVRDENGYCVRVPK 419 Query: 419 GEPGLLISRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWD 478 GE GLL+ ++ PF GYAG T+ K L DVFKKGD+Y N+GDL++ D +NF+YF D Sbjct: 420 GEVGLLVCKITQLTPFNGYAGAKAQTEKKKLRDVFKKGDLYFNSGDLLMVDHENFIYFHD 479 Query: 479 RTGDTFRWKGENVATTEVADVIGMLDFIQEANVYGVAISGYEGRAGMASIILKPNTSLDL 538 R GDTFRWKGENVATTEVAD +G++DF+QE NVYGV + +EGR GMASI +K N D Sbjct: 480 RVGDTFRWKGENVATTEVADTVGLVDFVQEVNVYGVHVPDHEGRIGMASIKMKENHEFDG 539 Query: 539 EKVYEQVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQLVEDGFNPLKISEPLYFMDNLK 598 +K+++ + +LP+YA PRFLRIQ+ +E TGTFK K LVE+GFNP I + LYF+D+ Sbjct: 540 KKLFQHIADYLPSYARPRFLRIQDTIEITGTFKHRKMTLVEEGFNPAVIKDALYFLDDTA 599 Query: 599 KSYVLLTRELYDQIMLGEIKL 619 K YV +T ++Y+ I +KL Sbjct: 600 KMYVPMTEDIYNAISAKTLKL 620 >gi|227499621 solute carrier family 27 (fatty acid transporter), member 2 isoform 2 [Homo sapiens] Length = 567 Score = 571 bits (1471), Expect = e-163 Identities = 292/621 (47%), Positives = 394/621 (63%), Gaps = 56/621 (9%) Query: 1 MLLSWLTVLGAGMVVLHFLQKLLFPYFWDDFWFVLKVVLIIIRLKKYEKRGELVTVLDKF 60 ML + TVL AG++ L L L PYF+ D + LKV + R++ Y KR T+L F Sbjct: 1 MLSAIYTVL-AGLLFLPLLVNLCCPYFFQDIGYFLKVAAVGRRVRSYGKRRPARTILRAF 59 Query: 61 LSHAKRQPRKPFIIYEGDIYTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVH 120 L A++ P KPF+++ + TY VD+RS++VA +H L++GD VALLM NEP +V Sbjct: 60 LEKARQTPHKPFLLFRDETLTYAQVDRRSNQVARALHDHLGLRQGDCVALLMGNEPAYVW 119 Query: 121 VWFGLAKLGCVVAFLNTNIRSNSLLNCIRACGPRALVVGADLLGTVEEILPSLS-ENISV 179 +W GL KLGC +A LN NIR+ SLL+C + CG + L+V +L VEEILPSL +++S+ Sbjct: 120 LWLGLVKLGCAMACLNYNIRAKSLLHCFQCCGAKVLLVSPELQAAVEEILPSLKKDDVSI 179 Query: 180 WGM-KDSVPQGVISLKEKLSTSPDEPVPRSHHVVSLLKSTCLYIFTSGTTGLPKAAVISQ 238 + + + S G+ S +K+ EP+P S + LYI+TSGTT Sbjct: 180 YYVSRTSNTDGIDSFLDKVDEVSTEPIPESWRSEVTFSTPALYIYTSGTT---------- 229 Query: 239 LQVLRGSAVLWAFGCTAHDIVYITLPLYHSSAAILGISGCVELGATCVLKKKFSASQFWS 298 GAT L+ KFSASQFW Sbjct: 230 -------------------------------------------GATLALRTKFSASQFWD 246 Query: 299 DCKKYDVTVFQYIGELCRYLCKQSKREGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVC 358 DC+KY+VTV QYIGEL RYLC ++ ++DHKVRLA+GNG+R DVWR+F+ RFG+I + Sbjct: 247 DCRKYNVTVIQYIGELLRYLCNSPQKPNDRDHKVRLALGNGLRGDVWRQFVKRFGDICIY 306 Query: 359 ELYAATESSISFMNYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKK 418 E YAATE +I FMNY ++GA+GR N K + T+DLIKYD +KDEP+R+E G+C+ V K Sbjct: 307 EFYAATEGNIGFMNYARKVGAVGRVNYLQKKIITYDLIKYDVEKDEPVRDENGYCVRVPK 366 Query: 419 GEPGLLISRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWD 478 GE GLL+ ++ PF GYAG T+ K L DVFKKGD+Y N+GDL++ D +NF+YF D Sbjct: 367 GEVGLLVCKITQLTPFNGYAGAKAQTEKKKLRDVFKKGDLYFNSGDLLMVDHENFIYFHD 426 Query: 479 RTGDTFRWKGENVATTEVADVIGMLDFIQEANVYGVAISGYEGRAGMASIILKPNTSLDL 538 R GDTFRWKGENVATTEVAD +G++DF+QE NVYGV + +EGR GMASI +K N D Sbjct: 427 RVGDTFRWKGENVATTEVADTVGLVDFVQEVNVYGVHVPDHEGRIGMASIKMKENHEFDG 486 Query: 539 EKVYEQVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQLVEDGFNPLKISEPLYFMDNLK 598 +K+++ + +LP+YA PRFLRIQ+ +E TGTFK K LVE+GFNP I + LYF+D+ Sbjct: 487 KKLFQHIADYLPSYARPRFLRIQDTIEITGTFKHRKMTLVEEGFNPAVIKDALYFLDDTA 546 Query: 599 KSYVLLTRELYDQIMLGEIKL 619 K YV +T ++Y+ I +KL Sbjct: 547 KMYVPMTEDIYNAISAKTLKL 567 >gi|13236579 solute carrier family 27 member 3 [Homo sapiens] Length = 730 Score = 518 bits (1334), Expect = e-147 Identities = 258/520 (49%), Positives = 349/520 (67%), Gaps = 2/520 (0%) Query: 102 LKKGDTVALLMSNEPDFVHVWFGLAKLGCVVAFLNTNIRSNSLLNCIRACGPRALVVGAD 161 L G TVALL+ P+F+ +WFGLAK G AF+ T +R LL+C+R+CG RALV+ + Sbjct: 211 LSPGATVALLLPAGPEFLWLWFGLAKAGLRTAFVPTALRRGPLLHCLRSCGARALVLAPE 270 Query: 162 LLGTVEEILPSL-SENISVWGMKDSV-PQGVISLKEKLSTSPDEPVPRSHHVVSLLKSTC 219 L ++E LP+L + + +W P G+ L ++S D PVP + TC Sbjct: 271 FLESLEPDLPALRAMGLHLWAAGPGTHPAGISDLLAEVSAEVDGPVPGYLSSPQSITDTC 330 Query: 220 LYIFTSGTTGLPKAAVISQLQVLRGSAVLWAFGCTAHDIVYITLPLYHSSAAILGISGCV 279 LYIFTSGTTGLPKAA IS L++L+ G D++Y+ LPLYH S ++LGI GC+ Sbjct: 331 LYIFTSGTTGLPKAARISHLKILQCQGFYQLCGVHQEDVIYLALPLYHMSGSLLGIVGCM 390 Query: 280 ELGATCVLKKKFSASQFWSDCKKYDVTVFQYIGELCRYLCKQSKREGEKDHKVRLAIGNG 339 +GAT VLK KFSA QFW DC+++ VTVFQYIGELCRYL Q + E+ HKVRLA+G+G Sbjct: 391 GIGATVVLKSKFSAGQFWEDCQQHRVTVFQYIGELCRYLVNQPPSKAERGHKVRLAVGSG 450 Query: 340 IRSDVWREFLDRFGNIKVCELYAATESSISFMNYTGRIGAIGRTNLFYKLLSTFDLIKYD 399 +R D W F+ RFG ++V E Y TE +++ +NYTG+ GA+GR + YK + F LI+YD Sbjct: 451 LRPDTWERFVRRFGPLQVLETYGLTEGNVATINYTGQRGAVGRASWLYKHIFPFSLIRYD 510 Query: 400 FQKDEPMRNEQGWCIHVKKGEPGLLISRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVY 459 EP+R+ QG C+ GEPGLL++ V+ ++PF GYAG + + KLL DVF+ GDV+ Sbjct: 511 VTTGEPIRDPQGHCMATSPGEPGLLVAPVSQQSPFLGYAGGPELAQGKLLKDVFRPGDVF 570 Query: 460 LNTGDLIVQDQDNFLYFWDRTGDTFRWKGENVATTEVADVIGMLDFIQEANVYGVAISGY 519 NTGDL+V D FL F DRTGDTFRWKGENVATTEVA+V LDF+QE NVYGV + G+ Sbjct: 571 FNTGDLLVCDDQGFLRFHDRTGDTFRWKGENVATTEVAEVFEALDFLQEVNVYGVTVPGH 630 Query: 520 EGRAGMASIILKPNTSLDLEKVYEQVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQLVE 579 EGRAGMA+++L+P +LDL ++Y V LP YA PRFLR+QE + T TFK K ++ Sbjct: 631 EGRAGMAALVLRPPHALDLMQLYTHVSENLPPYARPRFLRLQESLATTETFKQQKVRMAN 690 Query: 580 DGFNPLKISEPLYFMDNLKKSYVLLTRELYDQIMLGEIKL 619 +GF+P +S+PLY +D +Y+ LT Y ++ G +++ Sbjct: 691 EGFDPSTLSDPLYVLDQAVGAYLPLTTARYSALLAGNLRI 730 >gi|13325057 solute carrier family 27 (fatty acid transporter), member 5 [Homo sapiens] Length = 690 Score = 497 bits (1280), Expect = e-140 Identities = 259/601 (43%), Positives = 385/601 (64%), Gaps = 11/601 (1%) Query: 30 DFWFVLKVVLIIIRLKKYEKRGELVTVLDKFLSHAKRQPRKPFIIYEGD---IYTYQDVD 86 D F+ K++ + ++++ R T +D F A+ QP + +++ G T+ ++D Sbjct: 90 DVIFLAKILHLGLKIRGCLSRQPPDTFVDAFERRARAQPGRALLVWTGPGAGSVTFGELD 149 Query: 87 KRSSRVAHVFL----NHSSLKKGDTVALLM--SNEPDFVHVWFGLAKLGCVVAFLNTNIR 140 R+ + A + +SL G+ ALL+ S + +W GLAKLGC A++N + R Sbjct: 150 ARACQAAWALKAELGDPASLCAGEPTALLVLASQAVPALCMWLGLAKLGCPTAWINPHGR 209 Query: 141 SNSLLNCIRACGPRALVVGADLLGTVEEILPSL-SENISVWGMKDSVPQ-GVISLKEKLS 198 L + + + G R LVV DL ++EEILP L +ENI + + + P GV +L L Sbjct: 210 GMPLAHSVLSSGARVLVVDPDLRESLEEILPKLQAENIRCFYLSHTSPTPGVGALGAALD 269 Query: 199 TSPDEPVPRSHHVVSLLKSTCLYIFTSGTTGLPKAAVISQLQVLRGSAVLWAFGCTAHDI 258 +P PVP +S L+I+TSGTTGLPK A+++ +VL+ S +L G TA D+ Sbjct: 270 AAPSHPVPADLRAGITWRSPALFIYTSGTTGLPKPAILTHERVLQMSKMLSLSGATADDV 329 Query: 259 VYITLPLYHSSAAILGISGCVELGATCVLKKKFSASQFWSDCKKYDVTVFQYIGELCRYL 318 VY LPLYH ++GI GC++LGATCVL KFS S FW DC+++ VTV Y+GEL RYL Sbjct: 330 VYTVLPLYHVMGLVVGILGCLDLGATCVLAPKFSTSCFWDDCRQHGVTVILYVGELLRYL 389 Query: 319 CKQSKREGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVCELYAATESSISFMNYTGRIG 378 C ++ ++ H VRLA+GNG+R+DVW F RFG I++ E+Y +TE ++ +NY GR G Sbjct: 390 CNIPQQPEDRTHTVRLAMGNGLRADVWETFQQRFGPIRIWEVYGSTEGNMGLVNYVGRCG 449 Query: 379 AIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLLISRVNAKNPFFGYA 438 A+G+ + ++LS F+L+++D + EP+R+ QG+CI V GEPGLL+++V ++ PF GY Sbjct: 450 ALGKMSCLLRMLSPFELVQFDMEAAEPVRDNQGFCIPVGLGEPGLLLTKVVSQQPFVGYR 509 Query: 439 GPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTFRWKGENVATTEVAD 498 GP + ++ KL+ +V + GDVY NTGD++ D++ FLYF DR GDTFRWKGENV+T EV Sbjct: 510 GPRELSERKLVRNVRQSGDVYYNTGDVLAMDREGFLYFRDRLGDTFRWKGENVSTHEVEG 569 Query: 499 VIGMLDFIQEANVYGVAISGYEGRAGMASIILKPNTSLDLEKVYEQVVTFLPAYACPRFL 558 V+ +DF+Q+ NVYGV + G EG+ GMA++ L P + D EK+Y+ V +LPAYA P F+ Sbjct: 570 VLSQVDFLQQVNVYGVCVPGCEGKVGMAAVQLAPGQTFDGEKLYQHVRAWLPAYATPHFI 629 Query: 559 RIQEKMEATGTFKLLKHQLVEDGFNPLKISEPLYFMDNLKKSYVLLTRELYDQIMLGEIK 618 RIQ+ ME T TFKL+K +LV +GFN + +PL+ +DN +S+ LT E+Y + G + Sbjct: 630 RIQDAMEVTSTFKLMKTRLVREGFNVGIVVDPLFVLDNRAQSFRPLTAEMYQAVCEGTWR 689 Query: 619 L 619 L Sbjct: 690 L 690 >gi|40807357 solute carrier family 27 (fatty acid transporter), member 4 [Homo sapiens] Length = 643 Score = 422 bits (1084), Expect = e-118 Identities = 249/618 (40%), Positives = 350/618 (56%), Gaps = 23/618 (3%) Query: 22 LLFPYFWDDFWFVLKV-------------VLIIIRLKKYEKRGELVTVLDKFLSHAKRQP 68 LLF Y W ++V VL+ ++ K + E TV F S +R P Sbjct: 29 LLFLYLGSGGWRFIRVFIKTIRRDIFGGLVLLKVKAKVRQCLQERRTVPILFASTVRRHP 88 Query: 69 RKPFIIYEGDI--YTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLA 126 K +I+EG +T++ +D+ SS VA+ FL L GD A+ M N +FV +W G+A Sbjct: 89 DKTALIFEGTDTHWTFRQLDEYSSSVAN-FLQARGLASGDVAAIFMENRNEFVGLWLGMA 147 Query: 127 KLGCVVAFLNTNIRSNSLLNCIRACGPRALVVGADLLGTVEEILPSLSENISVWGMKDSV 186 KLG A +NTN+R ++LL+C+ RALV G+++ + E+ SL ++S++ Sbjct: 148 KLGVEAALINTNLRRDALLHCLTTSRARALVFGSEMASAICEVHASLDPSLSLFCSGSWE 207 Query: 187 PQGVISLKEKLSTS-PDEPVPRSHHVVSLLKSTCLYIFTSGTTGLPKAAVISQLQVLRGS 245 P V E L D P YI+TSGTTGLPKAA++ + R + Sbjct: 208 PGAVPPSTEHLDPLLKDAPKHLPSCPDKGFTDKLFYIYTSGTTGLPKAAIVVHSRYYRMA 267 Query: 246 A-VLWAFGCTAHDIVYITLPLYHSSAAILGISGCVELGATCVLKKKFSASQFWSDCKKYD 304 A V + F +DIVY LPLYHS+ I+GI C+ G T V++KKFSAS+FW DC KY+ Sbjct: 268 ALVYYGFRMRPNDIVYDCLPLYHSAGNIVGIGQCLLHGMTVVIRKKFSASRFWDDCIKYN 327 Query: 305 VTVFQYIGELCRYLCKQSKREGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVCELYAAT 364 T+ QYIGELCRYL Q RE E H+VR+A+GNG+R +W F RF +V E Y AT Sbjct: 328 CTIVQYIGELCRYLLNQPPREAENQHQVRMALGNGLRQSIWTNFSSRFHIPQVAEFYGAT 387 Query: 365 ESSISFMNYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLL 424 E + S N+ ++GA G + + L++ + E +R G CI + GEPG L Sbjct: 388 ECNCSLGNFDSQVGACGFNSRILSFVYPIRLVRVNEDTMELIRGPDGVCIPCQPGEPGQL 447 Query: 425 ISRVNAKNP---FFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTG 481 + R+ K+P F GY + K K+ DVFKKGD TGD++V D+ +LYF DRTG Sbjct: 448 VGRIIQKDPLRRFDGYLNQGANNK-KIAKDVFKKGDQAYLTGDVLVMDELGYLYFRDRTG 506 Query: 482 DTFRWKGENVATTEVADVIGMLDFIQEANVYGVAISGYEGRAGMASIILKPNTSLDLEKV 541 DTFRWKGENV+TTEV + L + + VYGV + G EGRAGMA+ + P + DLE+ Sbjct: 507 DTFRWKGENVSTTEVEGTLSRLLDMADVAVYGVEVPGTEGRAGMAA-VASPTGNCDLERF 565 Query: 542 YEQVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQLVEDGFNPLKISEPLYFMDNLKKSY 601 + + LP YA P FLR+ ++ TGT+K K +L ++GF+P + +PL+++D K Y Sbjct: 566 AQVLEKELPLYARPIFLRLLPELHKTGTYKFQKTELRKEGFDPAIVKDPLFYLDAQKGRY 625 Query: 602 VLLTRELYDQIMLGEIKL 619 V L +E Y +I GE KL Sbjct: 626 VPLDQEAYSRIQAGEEKL 643 >gi|38524616 solute carrier family 27, member 1 [Homo sapiens] Length = 646 Score = 410 bits (1053), Expect = e-114 Identities = 227/603 (37%), Positives = 354/603 (58%), Gaps = 23/603 (3%) Query: 30 DFWFVLKVVLIIIRLKKYEKRGELVTVLDKFLSHAKRQPRKPFIIYEG--DIYTYQDVDK 87 D + + ++ + + L+++++ G + + F + +RQP + ++ G + +T+ +D Sbjct: 54 DLFGLSVLIRVRLELRRHQRAGHTIPRI--FQAVVQRQPERLALVDAGTGECWTFAQLDA 111 Query: 88 RSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLAKLGCVVAFLNTNIRSNSLLNC 147 S+ VA++F GD VA+ + P+FV +W GLAK G A LN N+R L C Sbjct: 112 YSNAVANLF-RQLGFAPGDVVAIFLEGRPEFVGLWLGLAKAGMEAALLNVNLRREPLAFC 170 Query: 148 IRACGPRALVVGADLLGTVEEILPSLSENISVWGMKDSVPQGVIS-------LKEKLSTS 200 + G +AL+ G +++ V E+ L +++ + D P+G++ L ++ ST+ Sbjct: 171 LGTSGAKALIFGGEMVAAVAEVSGHLGKSLIKFCSGDLGPEGILPDTHLLDPLLKEASTA 230 Query: 201 PDEPVPRSHHVVSLLKSTCLYIFTSGTTGLPKAAVISQLQVLRGSAV-LWAFGCTAHDIV 259 P +P + YI+TSGTTGLPKAA++ + R +A A+ A D++ Sbjct: 231 PLAQIPSKG-----MDDRLFYIYTSGTTGLPKAAIVVHSRYYRMAAFGHHAYRMQAADVL 285 Query: 260 YITLPLYHSSAAILGISGCVELGATCVLKKKFSASQFWSDCKKYDVTVFQYIGELCRYLC 319 Y LPLYHS+ I+G+ C+ G T VL+KKFSAS+FW DC KY+ TV QYIGE+CRYL Sbjct: 286 YDCLPLYHSAGNIIGVGQCLIYGLTVVLRKKFSASRFWDDCIKYNCTVVQYIGEICRYLL 345 Query: 320 KQSKREGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVCELYAATESSISFMNYTGRIGA 379 KQ RE E+ H+VRLA+GNG+R +W EF +RFG ++ E Y ATE + S N G++G+ Sbjct: 346 KQPVREAERRHRVRLAVGNGLRPAIWEEFTERFGVRQIGEFYGATECNCSIANMDGKVGS 405 Query: 380 IGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLLISRVNAKNP---FFG 436 G + + L+K + E +R+ QG CI + GEPGLL+ ++N ++P F G Sbjct: 406 CGFNSRILPHVYPIRLVKVNEDTMELLRDAQGLCIPCQAGEPGLLVGQINQQDPLRRFDG 465 Query: 437 YAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTFRWKGENVATTEV 496 Y T K+ VF KGD +GD++V D+ ++YF DR+GDTFRW+GENV+TTEV Sbjct: 466 YVSE-SATSKKIAHSVFSKGDSAYLSGDVLVMDELGYMYFRDRSGDTFRWRGENVSTTEV 524 Query: 497 ADVIGMLDFIQEANVYGVAISGYEGRAGMASIILKPNTSLDLEKVYEQVVTFLPAYACPR 556 V+ L + VYGVA+ G EG+AGMA+ + P++ LD +Y+++ L YA P Sbjct: 525 EGVLSRLLGQTDVAVYGVAVPGVEGKAGMAA-VADPHSLLDPNAIYQELQKVLAPYARPI 583 Query: 557 FLRIQEKMEATGTFKLLKHQLVEDGFNPLKISEPLYFMDNLKKSYVLLTRELYDQIMLGE 616 FLR+ +++ TGTFK+ K +L +GF+P + S+ L+F+D + Y+ L +Y +I G Sbjct: 584 FLRLLPQVDTTGTFKIQKTRLQREGFDPRQTSDRLFFLDLKQGHYLPLNEAVYTRICSGA 643 Query: 617 IKL 619 L Sbjct: 644 FAL 646 >gi|28416953 acyl-CoA synthetase short-chain family member 1 [Homo sapiens] Length = 689 Score = 68.9 bits (167), Expect = 1e-11 Identities = 116/566 (20%), Positives = 218/566 (38%), Gaps = 62/566 (10%) Query: 51 GELVTVLDKFLSHAKRQPRKPFIIYEGDI------YTYQDVDKRSSRVAHVFLNHSSLKK 104 G+L ++ H ++ P +I+E D TY+++ + + R+A+ H + + Sbjct: 106 GQLNVSVNCLDQHVRKSPESVALIWERDEPGTEVRITYRELLETTCRLANTLKRHG-VHR 164 Query: 105 GDTVALLMSNEPDFVHVWFGLAKLGCVVAFLNTNIRSNSLLNCIRACGPRALVVG----- 159 GD VA+ M P V A++G V + + SL I + ++ Sbjct: 165 GDRVAIYMPVSPLAVAAMLACARIGAVHTVIFAGFSAESLAGRINDAKCKVVITFNQGLR 224 Query: 160 ----ADLLGTVEEIL---PSLSENISVWGMKDSVPQGVISLKEKLSTSPDEPVPRSHHVV 212 +L V+E + P++ + + V G + + + + ++PV + Sbjct: 225 GGRVVELKKIVDEAVKHCPTVQHVLVAHRTDNKVHMGDLDVPLEQEMAKEDPVCAPESMG 284 Query: 213 SLLKSTCLYIFTSGTTGLPKAAVISQLQVLRGSAVLW----------AFGCTAHDIVYIT 262 S + ++TSG+TG+PK V +Q L +A+ FGC A DI +IT Sbjct: 285 S--EDMLFMLYTSGSTGMPKGIVHTQAGYLLYAALTHKLVFDHQPGDIFGCVA-DIGWIT 341 Query: 263 LPLYHSSAAILGISGCVELGATCVLKKKF----SASQFWSDCKKYDVTVFQYIGELCRYL 318 Y + G + GAT VL + +A ++W ++ + F R L Sbjct: 342 GHSY-------VVYGPLCNGATSVLFESTPVYPNAGRYWETVERLKINQFYGAPTAVRLL 394 Query: 319 CKQS----KREGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVCELYAATESSISFMNYT 374 K K+ + ++G I + W E+L R C L + T Sbjct: 395 LKYGDAWVKKYDRSSLRTLGSVGEPINCEAW-EWLHRVVGDSRCTLV-----DTWWQTET 448 Query: 375 GRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLLISRVNAKNPF 434 G I R + + ++ F + +E+G + L IS+ + Sbjct: 449 GGICIAPRPSEEGAEILPAMAMRPFFGIVPVLMDEKGSVVEGSNVSGALCISQA-----W 503 Query: 435 FGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTFRWKGENVATT 494 G A + + FK Y TGD + + + R D G + T Sbjct: 504 PGMARTIYGDHQRFVDAYFKAYPGYYFTGDGAYRTEGGYYQITGRMDDVINISGHRLGTA 563 Query: 495 EVADVIGMLDFIQEANVYGVAISGYEGRAGMASIILKP---NTSLDLEKVYEQVVTFLPA 551 E+ D I + E+ V G +G A A I++K ++ + ++++ V T + Sbjct: 564 EIEDAIADHPAVPESAVIGYP-HDIKGEAAFAFIVVKDSAGDSDVVVQELKSMVATKIAK 622 Query: 552 YACPRFLRIQEKMEATGTFKLLKHQL 577 YA P + + +++ T + K+++ L Sbjct: 623 YAVPDEILVVKRLPKTRSGKVMRRLL 648 >gi|42544132 SA hypertension-associated homolog isoform 1 [Homo sapiens] Length = 586 Score = 67.0 bits (162), Expect = 5e-11 Identities = 108/514 (21%), Positives = 210/514 (40%), Gaps = 46/514 (8%) Query: 80 YTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLAKLGCVVAFLNTNI 139 ++++++ S + A++ SL++GD V L++ P++ + G V+ T + Sbjct: 95 WSFEELGSLSRKFANILSEACSLQRGDRVILILPRVPEWWLANVACLRTGTVLIPGTTQL 154 Query: 140 RSNSLLNCIRACGPRALVVGADLLGTVEEILPSLSENI-SVWGMKDSVPQGVISLKEKLS 198 +L +++ ++ D+L + + S EN+ S + ++ +G +LKE + Sbjct: 155 TQKDILYRLQSSKANCIITN-DVLAPAVDAVASKCENLHSKLIVSENSREGWGNLKELMK 213 Query: 199 TSPDEPVPRSHHVVSLLKSTCLYIF-TSGTTGLPKAAVISQLQVLRGSAVLWAF--GCTA 255 + D SH V + + IF TSGT+G PK + G +V F T Sbjct: 214 HASD-----SHTCVKTKHNEIMAIFFTSGTSGYPKMTAHTHSSFGLGLSVNGRFWLDLTP 268 Query: 256 HDIVYITLPLYHSSAAILGISGCVELGATCVLKK---KFSASQFWSDCKKYDVTVFQYIG 312 D+++ T + +A + GA CV +F + KY +TVF Sbjct: 269 SDVMWNTSDTGWAKSAWSSVFSPWIQGA-CVFTHHLPRFEPTSILQTLSKYPITVFCSAP 327 Query: 313 ELCRYLCKQSKREGE-KDHKVRLAIGNGIRSDVWREFLDRFGNIKVCELYAATESSISFM 371 + R L + + K K ++ G I DV ++ ++ G + + E Y TE+ + Sbjct: 328 TVYRMLVQNDITSYKFKSLKHCVSAGEPITPDVTEKWRNKTG-LDIYEGYGQTETVLICG 386 Query: 372 NYTG---RIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLLISRV 428 N+ G + G++G+ + FD+ D + + G+ G + +V Sbjct: 387 NFKGMKIKPGSMGKPS------PAFDVKIVDVNGNV-----------LPPGQEGDIGIQV 429 Query: 429 NAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTFRWKG 488 PF G Y K + +G+ Y+ TGD D+D + +F R D G Sbjct: 430 LPNRPF-GLFTHYVDNPSKTASTL--RGNFYI-TGDRGYMDKDGYFWFVARADDVILSSG 485 Query: 489 ENVATTEVADVIGMLDFIQEANVYGVAISGYEGRAGMASIILKPNTSLD-----LEKVYE 543 + EV + + + E+ V + G A ++L P+ ++++ E Sbjct: 486 YRIGPFEVENALNEHPSVAESAVVS-SPDPIRGEVVKAFVVLNPDYKSHDQEQLIKEIQE 544 Query: 544 QVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQL 577 V Y PR + +++ T + K +++L Sbjct: 545 HVKKTTAPYKYPRKVEFIQELPKTISGKTKRNEL 578 >gi|122937307 acyl-CoA synthetase medium-chain family member 4 [Homo sapiens] Length = 580 Score = 64.3 bits (155), Expect = 3e-10 Identities = 114/518 (22%), Positives = 203/518 (39%), Gaps = 54/518 (10%) Query: 80 YTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLAKLGCVVAFLNTNI 139 ++++++ S + A+V L++GD +A+++ P++ V + G + + Sbjct: 89 WSFRELGSLSRKAANVLTKPCGLQRGDRLAVILPRIPEWWLVNVACIRTGIIFMPGTIQL 148 Query: 140 RSNSLLNCIRACGPRALVVGADLLGTVEEIL---PSLSENISVWGMKDSVPQ---GVISL 193 + +L +RA + +V ++ VE I+ P L + V PQ G +S Sbjct: 149 TAKDILYRLRASKAKCIVASEEVAPAVESIVLECPDLKTKLLV------SPQSWNGWLSF 202 Query: 194 KEKLSTSPDEPVPRSHHVVSLLKSTCLYI-FTSGTTGLPKAAVISQLQVLRGSAVLWAF- 251 +E + +E H V + I FTSGTTG PK A SQ + G + + Sbjct: 203 QELFQFASEE-----HSCVETGSQEPMTIYFTSGTTGFPKMAQHSQSSLGIGFTLCGRYW 257 Query: 252 -GCTAHDIVYITLPLYHSSAAILGISGCVELGATCVLKK--KFSASQFWSDCKKYDVTVF 308 + DI++ AAI + GA + + +F F Y +T Sbjct: 258 LDLKSSDIIWNMSDTGWVKAAIGSVFSSWLCGACVFVHRMAQFDTDTFLDTLTTYPITTL 317 Query: 309 QYIGELCRYLC-KQSKREGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVCELYAATESS 367 + R L K KR K + L G + +V ++ + G +++ E Y TE Sbjct: 318 CSPPTVYRMLVQKDLKRYKFKSLRHCLTGGEPLNPEVLEQWRVQTG-LELYEGYGQTEVG 376 Query: 368 ISFMNYTG---RIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLL 424 + N G + G++G+ ++ YD Q + N + G+ G + Sbjct: 377 MICANQKGQEIKPGSMGK-----------GMLPYDVQIIDENGNV------LPPGKEGEI 419 Query: 425 ISRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTF 484 R+ PF + Y K + +GD Y+ TGD V D D + +F R D Sbjct: 420 ALRLKPTRPFC-FFSKYVDNPQKTAATI--RGDFYV-TGDRGVMDSDGYFWFVGRADDVI 475 Query: 485 RWKGENVATTEVADVIGMLDFIQEANVYGVAISGYEGRAGMASIIL-KPNTSLDLEK--- 540 G + EV + + E+ V + G A ++L P S + EK Sbjct: 476 ISSGYRIGPFEVESALIEHPAVVESAVVS-SPDQIRGEVVKAFVVLAAPFKSYNPEKLTL 534 Query: 541 -VYEQVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQL 577 + + V Y PR + +++ T T K+ ++ L Sbjct: 535 ELQDHVKKSTAPYKYPRKVEFVQELPKTITGKIKRNVL 572 >gi|157311624 acyl-CoA synthetase medium-chain family member 2B [Homo sapiens] Length = 577 Score = 63.9 bits (154), Expect = 4e-10 Identities = 110/516 (21%), Positives = 207/516 (40%), Gaps = 49/516 (9%) Query: 79 IYTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLAKLGCVVAFLNTN 138 ++ ++++ + S + A++ L++GD VA+++ P++ V G + G + Sbjct: 80 MWNFRELSENSQQAANILSGACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMPGTIQ 139 Query: 139 IRSNSLLNCIRACGPRALVVGADLLGTVEEIL---PSLSENISVWGMKDSVPQGVISLKE 195 ++S +L ++ +A+V G +++ V+ + PSL + V + G ++ K+ Sbjct: 140 MKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIKLLV---SEKSCDGWLNFKK 196 Query: 196 KLSTSPDEPVPRSHHVVSL--LKSTCLYIFTSGTTGLPKAAVISQLQV-LRGSAVLWAFG 252 L+ + +HH V +++ +Y FTSGT+GLPK A S + L+ G Sbjct: 197 LLNEAST-----THHCVETGSQEASAIY-FTSGTSGLPKMAEHSYSSLGLKAKMDAGWTG 250 Query: 253 CTAHDIVYITLPLYHSSAAILGISGCV----ELGATCV--LKKKFSASQFWSDCKKYDVT 306 A DI++ + IL I G + LGA L KF Y + Sbjct: 251 LQASDIMW----TISDTGWILNILGSLLESWTLGACTFVHLLPKFDPLVILKTLSSYPIK 306 Query: 307 VFQYIGELCRYLCKQSKREGEKDHKVR-LAIGNGIRSDVWREFLDRFGNIKVCELYAATE 365 + R L +Q + H LA G + + + + G + + E Y TE Sbjct: 307 SMMGAPIVYRMLLQQDLSSYKFPHLQNCLAGGESLLPETLENWRAQTG-LDIREFYGQTE 365 Query: 366 SSISFMNYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLLI 425 + ++ M + +T YD Q + N + G G + Sbjct: 366 TGLTCM--------VSKTMKIKPGYMGTAASCYDVQVIDDKGNV------LPPGTEGDIG 411 Query: 426 SRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTFR 485 RV P ++G Y DK ++ +GD +L GD ++D+D + F R D Sbjct: 412 IRVKPIRPIGIFSG-YVENPDKTAANI--RGDFWL-LGDRGIKDEDGYFQFMGRADDIIN 467 Query: 486 WKGENVATTEVADVIGMLDFIQEANVYGV--AISGYEGRAG--MASIILKPNTSLDLEKV 541 G + +EV + + + E V + G +A +AS L + +++ Sbjct: 468 SSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVILASQFLSHDPEQLTKEL 527 Query: 542 YEQVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQL 577 + V + Y PR + + T T K+ + +L Sbjct: 528 QQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRTKL 563 >gi|157311622 acyl-CoA synthetase medium-chain family member 2B [Homo sapiens] Length = 577 Score = 63.9 bits (154), Expect = 4e-10 Identities = 110/516 (21%), Positives = 207/516 (40%), Gaps = 49/516 (9%) Query: 79 IYTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLAKLGCVVAFLNTN 138 ++ ++++ + S + A++ L++GD VA+++ P++ V G + G + Sbjct: 80 MWNFRELSENSQQAANILSGACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMPGTIQ 139 Query: 139 IRSNSLLNCIRACGPRALVVGADLLGTVEEIL---PSLSENISVWGMKDSVPQGVISLKE 195 ++S +L ++ +A+V G +++ V+ + PSL + V + G ++ K+ Sbjct: 140 MKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIKLLV---SEKSCDGWLNFKK 196 Query: 196 KLSTSPDEPVPRSHHVVSL--LKSTCLYIFTSGTTGLPKAAVISQLQV-LRGSAVLWAFG 252 L+ + +HH V +++ +Y FTSGT+GLPK A S + L+ G Sbjct: 197 LLNEAST-----THHCVETGSQEASAIY-FTSGTSGLPKMAEHSYSSLGLKAKMDAGWTG 250 Query: 253 CTAHDIVYITLPLYHSSAAILGISGCV----ELGATCV--LKKKFSASQFWSDCKKYDVT 306 A DI++ + IL I G + LGA L KF Y + Sbjct: 251 LQASDIMW----TISDTGWILNILGSLLESWTLGACTFVHLLPKFDPLVILKTLSSYPIK 306 Query: 307 VFQYIGELCRYLCKQSKREGEKDHKVR-LAIGNGIRSDVWREFLDRFGNIKVCELYAATE 365 + R L +Q + H LA G + + + + G + + E Y TE Sbjct: 307 SMMGAPIVYRMLLQQDLSSYKFPHLQNCLAGGESLLPETLENWRAQTG-LDIREFYGQTE 365 Query: 366 SSISFMNYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLLI 425 + ++ M + +T YD Q + N + G G + Sbjct: 366 TGLTCM--------VSKTMKIKPGYMGTAASCYDVQVIDDKGNV------LPPGTEGDIG 411 Query: 426 SRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTFR 485 RV P ++G Y DK ++ +GD +L GD ++D+D + F R D Sbjct: 412 IRVKPIRPIGIFSG-YVENPDKTAANI--RGDFWL-LGDRGIKDEDGYFQFMGRADDIIN 467 Query: 486 WKGENVATTEVADVIGMLDFIQEANVYGV--AISGYEGRAG--MASIILKPNTSLDLEKV 541 G + +EV + + + E V + G +A +AS L + +++ Sbjct: 468 SSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVILASQFLSHDPEQLTKEL 527 Query: 542 YEQVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQL 577 + V + Y PR + + T T K+ + +L Sbjct: 528 QQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRTKL 563 >gi|38505220 acyl-CoA synthetase medium-chain family member 5 [Homo sapiens] Length = 579 Score = 62.0 bits (149), Expect = 2e-09 Identities = 114/517 (22%), Positives = 202/517 (39%), Gaps = 53/517 (10%) Query: 80 YTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLAKLGCVVAFLNTNI 139 ++++++ K+S + A+V L+ GD + L++ P++ V + G V+ T + Sbjct: 90 WSFEELGKQSRKAANVLGGACGLQPGDRMMLVLPRLPEWWLVSVACMRTGTVMIPGVTQL 149 Query: 140 RSNSLLNCIRACGPRALVVGADLLGTVEEI---LPSLSENISVWGMKDSVPQGVISLKEK 196 L ++A ++++ L V+ I PSL + V DS G ++ +E Sbjct: 150 TEKDLKYRLQASRAKSIITSDSLAPRVDAISAECPSLQTKLLV---SDSSRPGWLNFREL 206 Query: 197 LSTSPDEPVPRSHHVVSLLKSTCLYI-FTSGTTGLPKAAVISQLQVLRG---SAVLWAFG 252 L + E H+ + L I FTSGTTG PK SQ G S W Sbjct: 207 LREASTE-----HNCMRTKSRDPLAIYFTSGTTGAPKMVEHSQSSYGLGFVASGRRWV-A 260 Query: 253 CTAHDIVYITLPLYHSSAAILGISGCVELGATCVL---KKKFSASQFWSDCKKYDVTVFQ 309 T DI + T AA S +C+ + A + K+ +T Sbjct: 261 LTESDIFWNTTDTGWVKAAWTLFSAWP--NGSCIFVHELPRVDAKVILNTLSKFPITTLC 318 Query: 310 YIGELCRYLCKQS-KREGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVCELYAATESSI 368 + + R L ++ R + + L G + DV ++ + G +++ E Y +E+ + Sbjct: 319 CVPTIFRLLVQEDLTRYQFQSLRHCLTGGEALNPDVREKWKHQTG-VELYEGYGQSETVV 377 Query: 369 SFMNYTG---RIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLLI 425 N G + G++G+ + YD Q + N + GE G + Sbjct: 378 ICANPKGMKIKSGSMGKAS-----------PPYDVQIVDDEGNV------LPPGEEGNVA 420 Query: 426 SRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTFR 485 R+ PF + Y +K ++GD Y+ TGD D+D + +F R D Sbjct: 421 VRIRPTRPFC-FFNCYLDNPEKTAAS--EQGDFYI-TGDRARMDKDGYFWFMGRNDDVIN 476 Query: 486 WKGENVATTEVADVIGMLDFIQEANVYGVAISGYEGRAGMASIILKP-NTSLDLE----K 540 + EV + + E+ V + G A I+L P +S D E + Sbjct: 477 SSSYRIGPVEVESALAEHPAVLESAVVS-SPDPIRGEVVKAFIVLTPAYSSHDPEALTRE 535 Query: 541 VYEQVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQL 577 + E V Y PR + ++ T + K+ + +L Sbjct: 536 LQEHVKRVTAPYKYPRKVAFVSELPKTVSGKIQRSKL 572 >gi|115511026 acyl-CoA synthetase medium-chain family member 1 [Homo sapiens] Length = 577 Score = 61.6 bits (148), Expect = 2e-09 Identities = 120/557 (21%), Positives = 213/557 (38%), Gaps = 77/557 (13%) Query: 56 VLDKFLSHAKRQPRKP-----FIIYEGDI--YTYQDVDKRSSRVAHVFLNHSSLKKGDTV 108 VLD + K R P ++ +GD ++++++ + RVA+VF L++GD + Sbjct: 55 VLDYWAQKEKEGKRGPNPAFWWVNGQGDEVKWSFREMGDLTRRVANVFTQTCGLQQGDHL 114 Query: 109 ALLMSNEPDFVHVWFGLAKLGCVVAFLNTNIRSNSLLNCIRACGPRALVVGADLLGTVEE 168 AL++ P++ V G + G + +++ +L ++ + +V L V+ Sbjct: 115 ALMLPRVPEWWLVAVGCMRTGIIFIPATILLKAKDILYRLQLSKAKGIVTIDALASEVDS 174 Query: 169 I---LPSLSENISVWGMKDSVPQGVISLKEKL-STSPDEPVPRSHHVVSLLKSTCLYIFT 224 I PSL + V D +G + + + S SP+ +S + + FT Sbjct: 175 IASQCPSLKTKLLV---SDHSREGWLDFRSLVKSASPEHTCVKSKTL-----DPMVIFFT 226 Query: 225 SGTTGLPKAAVIS-------------QLQVLRGSAVLWAFGCTAHDIVYITLPLYHSSAA 271 SGTTG PK A S +L+ L+ S V W + + I + +A Sbjct: 227 SGTTGFPKMAKHSHGLALQPSFPGSRKLRSLKTSDVSWCLSDSGWIVATIWTLVEPWTA- 285 Query: 272 ILGISGCVELGATCVLK--KKFSASQFWSDCKKYDVTVFQYIGELCRYLCKQSKREGEKD 329 G T + +F KY + F + + R + +Q Sbjct: 286 ----------GCTVFIHHLPQFDTKVIIQTLLKYPINHFWGVSSIYRMILQQDFTSIRFP 335 Query: 330 HKVRLAIGNGIRSDVWREFLDRFGNIKVCELYAATESSISFMNYTG---RIGAIGRTNLF 386 G + +E R + + E Y +E+ + Y G + G +G+ Sbjct: 336 ALEHCYTGGEVVLPKDQEEWKRRTGLLLYENYGQSETGLICATYWGMKIKPGFMGKATPP 395 Query: 387 YKLLSTFDLIKYDFQKDEPMRNEQGWCIHVK-KGEPGLLISRVNAKNPFFGYAGPYKHTK 445 Y D + +++G + +G G+ I V + F Y G + T Sbjct: 396 Y---------------DVQVIDDKGSILPPNTEGNIGIRIKPVRPVSLFMCYEGDPEKTA 440 Query: 446 DKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTFRWKGENVATTEVADVIGMLDF 505 K+ C GD Y NTGD D++ ++ F R+ D G + EV + Sbjct: 441 -KVEC-----GDFY-NTGDRGKMDEEGYICFLGRSDDIINASGYRIGPAEVESALVEHPA 493 Query: 506 IQEANVYGVAISGYEGRAGMASIILKP----NTSLDLEKVYEQVVTFLPA-YACPRFLRI 560 + E+ V G + G A I+L P + L K +Q V + A Y PR + Sbjct: 494 VAESAVVG-SPDPIRGEVVKAFIVLTPQFLSHDKDQLTKELQQHVKSVTAPYKYPRKVEF 552 Query: 561 QEKMEATGTFKLLKHQL 577 ++ T T K+ + +L Sbjct: 553 VSELPKTITGKIERKEL 569 >gi|239756507 PREDICTED: similar to Acyl-coenzyme A synthetase ACSM2B, mitochondrial isoform 2 [Homo sapiens] Length = 571 Score = 60.8 bits (146), Expect = 3e-09 Identities = 108/517 (20%), Positives = 207/517 (40%), Gaps = 57/517 (11%) Query: 79 IYTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLAKLGCVVAFLNTN 138 ++ ++++ + S + A+V L++GD VA+++ P++ V G + G + Sbjct: 80 MWNFRELSENSQQAANVLSGACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMPGTIQ 139 Query: 139 IRSNSLLNCIRACGPRALVVGADLLGTVEEIL---PSLSENISVWGMKDSVPQGVISLKE 195 ++S +L ++ +A+V G +++ V+ + PSL + V + G ++ K+ Sbjct: 140 MKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIKLLV---SEKSCDGWLNFKK 196 Query: 196 KLSTSPDEPVPRSHHVVSL--LKSTCLYIFTSGTTGLPKAAVISQLQV-LRGSAVLWAFG 252 L+ + +HH V +++ +Y FTSGT+GLPK A S + L+ G Sbjct: 197 LLNEAST-----THHCVETGSQEASAIY-FTSGTSGLPKMAEHSYSSLGLKAKMDAGWTG 250 Query: 253 CTAHDIVYITLPLYHSSAAILGISGCV----ELGATCV--LKKKFSASQFWSDCKKYDVT 306 A DI++ + IL I G + LGA L KF Y + Sbjct: 251 LQASDIMW----TISDTGWILNILGSLLESWTLGACTFVHLLPKFDPLVILKTLSSYPIK 306 Query: 307 VFQYIGELCRYLCKQSKREGEKDHKVR-LAIGNGIRSDVWREFLDRFGNIKVCELYAATE 365 + R L +Q + H LA G + + + + G + + E Y TE Sbjct: 307 SMMGAPIVYRMLLQQDLSSYKFPHLQNCLAGGESLLPETLENWRAQTG-LDIREFYGQTE 365 Query: 366 SSISFM-NYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLL 424 + ++ M + T +I + S +D+ F P + G+ Sbjct: 366 TGLTCMVSKTMKI----KPGYMGTAASCYDVQVIAFVHGSPRAGDLGF------------ 409 Query: 425 ISRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTF 484 A + G ++ DK ++ +GD +L GD ++D+D + F R D Sbjct: 410 -----AGTMTLSFCG-HQENPDKTAANI--RGDFWL-LGDRGIKDEDGYFQFMGRADDII 460 Query: 485 RWKGENVATTEVADVIGMLDFIQEANVYGV--AISGYEGRAG--MASIILKPNTSLDLEK 540 G + +EV + + + E V + G +A +AS L + ++ Sbjct: 461 NSSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVILASQFLSHDPEQLTKE 520 Query: 541 VYEQVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQL 577 + + V + Y PR + + T T K+ + +L Sbjct: 521 LQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRTKL 557 >gi|239756505 PREDICTED: similar to Acyl-coenzyme A synthetase ACSM2B, mitochondrial isoform 1 [Homo sapiens] Length = 571 Score = 60.8 bits (146), Expect = 3e-09 Identities = 108/517 (20%), Positives = 207/517 (40%), Gaps = 57/517 (11%) Query: 79 IYTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLAKLGCVVAFLNTN 138 ++ ++++ + S + A+V L++GD VA+++ P++ V G + G + Sbjct: 80 MWNFRELSENSQQAANVLSGACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMPGTIQ 139 Query: 139 IRSNSLLNCIRACGPRALVVGADLLGTVEEIL---PSLSENISVWGMKDSVPQGVISLKE 195 ++S +L ++ +A+V G +++ V+ + PSL + V + G ++ K+ Sbjct: 140 MKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIKLLV---SEKSCDGWLNFKK 196 Query: 196 KLSTSPDEPVPRSHHVVSL--LKSTCLYIFTSGTTGLPKAAVISQLQV-LRGSAVLWAFG 252 L+ + +HH V +++ +Y FTSGT+GLPK A S + L+ G Sbjct: 197 LLNEAST-----THHCVETGSQEASAIY-FTSGTSGLPKMAEHSYSSLGLKAKMDAGWTG 250 Query: 253 CTAHDIVYITLPLYHSSAAILGISGCV----ELGATCV--LKKKFSASQFWSDCKKYDVT 306 A DI++ + IL I G + LGA L KF Y + Sbjct: 251 LQASDIMW----TISDTGWILNILGSLLESWTLGACTFVHLLPKFDPLVILKTLSSYPIK 306 Query: 307 VFQYIGELCRYLCKQSKREGEKDHKVR-LAIGNGIRSDVWREFLDRFGNIKVCELYAATE 365 + R L +Q + H LA G + + + + G + + E Y TE Sbjct: 307 SMMGAPIVYRMLLQQDLSSYKFPHLQNCLAGGESLLPETLENWRAQTG-LDIREFYGQTE 365 Query: 366 SSISFM-NYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLL 424 + ++ M + T +I + S +D+ F P + G+ Sbjct: 366 TGLTCMVSKTMKI----KPGYMGTAASCYDVQVIAFVHGSPRAGDLGF------------ 409 Query: 425 ISRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTF 484 A + G ++ DK ++ +GD +L GD ++D+D + F R D Sbjct: 410 -----AGTMTLSFCG-HQENPDKTAANI--RGDFWL-LGDRGIKDEDGYFQFMGRADDII 460 Query: 485 RWKGENVATTEVADVIGMLDFIQEANVYGV--AISGYEGRAG--MASIILKPNTSLDLEK 540 G + +EV + + + E V + G +A +AS L + ++ Sbjct: 461 NSSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVILASQFLSHDPEQLTKE 520 Query: 541 VYEQVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQL 577 + + V + Y PR + + T T K+ + +L Sbjct: 521 LQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRTKL 557 >gi|58082049 acyl-CoA synthetase medium-chain family member 2A [Homo sapiens] Length = 577 Score = 60.1 bits (144), Expect = 6e-09 Identities = 90/431 (20%), Positives = 173/431 (40%), Gaps = 37/431 (8%) Query: 79 IYTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLAKLGCVVAFLNTN 138 ++ ++++ + S + A+V L++GD VA+++ P++ V G + G + Sbjct: 80 MWNFRELSENSQQAANVLSGACGLQRGDRVAVVLPRVPEWWLVILGCIRAGLIFMPGTIQ 139 Query: 139 IRSNSLLNCIRACGPRALVVGADLLGTVEEIL---PSLSENISVWGMKDSVPQGVISLKE 195 ++S +L ++ +A+V G +++ V+ + PSL + V + G ++ K+ Sbjct: 140 MKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIKLLV---SEKSCDGWLNFKK 196 Query: 196 KLSTSPDEPVPRSHHVVSL--LKSTCLYIFTSGTTGLPKAAVISQLQV-LRGSAVLWAFG 252 L+ + +HH V +++ +Y FTSGT+GLPK A S + L+ G Sbjct: 197 LLNEAST-----THHCVETGSQEASAIY-FTSGTSGLPKMAEHSYSSLGLKAKMDAGWTG 250 Query: 253 CTAHDIVYITLPLYHSSAAILGISGCVELGATCV--LKKKFSASQFWSDCKKYDVTVFQY 310 A DI++ + + LGA L KF Y + Sbjct: 251 LQASDIMWTISDTGWILNILCSLMEPWALGACTFVHLLPKFDPLVILKTLSSYPIKSMMG 310 Query: 311 IGELCRYLCKQSKREGEKDHKVR-LAIGNGIRSDVWREFLDRFGNIKVCELYAATESSIS 369 + R L +Q + H + +G + + + + G + + E Y TE+ ++ Sbjct: 311 APIVYRMLLQQDLSSYKFPHLQNCVTVGESLLPETLENWRAQTG-LDIRESYGQTETGLT 369 Query: 370 FMNYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLLISRVN 429 M + +T YD Q + N + G G + RV Sbjct: 370 CM--------VSKTMKIKPGYMGTAASCYDVQIIDDKGNV------LPPGTEGDIGIRVK 415 Query: 430 AKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTFRWKGE 489 P ++G Y DK ++ +GD +L GD ++D+D + F R D G Sbjct: 416 PIRPIGIFSG-YVDNPDKTAANI--RGDFWL-LGDRGIKDEDGYFQFMGRADDIINSSGY 471 Query: 490 NVATTEVADVI 500 + +EV + + Sbjct: 472 RIGPSEVENAL 482 >gi|187761345 acyl-CoA synthetase family member 3 [Homo sapiens] Length = 576 Score = 59.7 bits (143), Expect = 8e-09 Identities = 89/399 (22%), Positives = 153/399 (38%), Gaps = 55/399 (13%) Query: 220 LYIFTSGTTGLPKAAVISQLQ---VLRGSAVLWAFGCTAHDIVYITLPLYHSSAAILGIS 276 + I+TSGTTG PK + + V+ G WA+ T D++ LPL+H + + Sbjct: 198 MIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKWAW--TKDDVILHVLPLHHVHGVVNALL 255 Query: 277 GCVELGATCVLKKKFSASQFWSDCKKYD---VTVFQYIGELCRYLCKQSKREGEKDH--- 330 + +GATCV+ +FS Q W + + VF + + L + R + H Sbjct: 256 CPLWVGATCVMMPEFSPQQVWEKFLSSETPRINVFMAVPTIYTKLMEYYDRHFTQPHAQD 315 Query: 331 --------KVRLAIGNGIRSDVWREFLDRFGNI---KVCELYAATESSISF---MNYTGR 376 K+RL + + L+++ NI + E Y TE ++ + R Sbjct: 316 FLRAVCEEKIRLMVSGSAALPL--PVLEKWKNITGHTLLERYGMTEIGMALSGPLTTAVR 373 Query: 377 I-GAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLLIS--------- 426 + G++G + ++ + P R + IH + E G ++ Sbjct: 374 LPGSVG---------TPLPGVQVRIVSENPQREACSYTIHAEGDERGTKVTPGFEEKEGE 424 Query: 427 -RVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTFR 485 V + F Y + TK D + K TGD +V + + D + Sbjct: 425 LLVRGPSVFREYWNKPEETKSAFTLDGWFK------TGDTVVFKDGQYWIRGRTSVDIIK 478 Query: 486 WKGENVATTEVADVIGMLDFIQEANVYGVAISGYEGRAGMASIILKPNTSLDLEKVYEQV 545 G V+ EV + I + V GV + G+ A + L+ SL ++ E Sbjct: 479 TGGYKVSALEVEWHLLAHPSITDVAVIGVPDMTW-GQRVTAVVTLREGHSLSHRELKEWA 537 Query: 546 VTFLPAYACPRFLRIQEKMEATGTFKLLKHQLVEDGFNP 584 L YA P L + E++ K+ K L+ F+P Sbjct: 538 RNVLAPYAVPSELVLVEEIPRNQMGKIDKKALIRH-FHP 575 >gi|187761343 acyl-CoA synthetase family member 3 [Homo sapiens] Length = 576 Score = 59.7 bits (143), Expect = 8e-09 Identities = 89/399 (22%), Positives = 153/399 (38%), Gaps = 55/399 (13%) Query: 220 LYIFTSGTTGLPKAAVISQLQ---VLRGSAVLWAFGCTAHDIVYITLPLYHSSAAILGIS 276 + I+TSGTTG PK + + V+ G WA+ T D++ LPL+H + + Sbjct: 198 MIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKWAW--TKDDVILHVLPLHHVHGVVNALL 255 Query: 277 GCVELGATCVLKKKFSASQFWSDCKKYD---VTVFQYIGELCRYLCKQSKREGEKDH--- 330 + +GATCV+ +FS Q W + + VF + + L + R + H Sbjct: 256 CPLWVGATCVMMPEFSPQQVWEKFLSSETPRINVFMAVPTIYTKLMEYYDRHFTQPHAQD 315 Query: 331 --------KVRLAIGNGIRSDVWREFLDRFGNI---KVCELYAATESSISF---MNYTGR 376 K+RL + + L+++ NI + E Y TE ++ + R Sbjct: 316 FLRAVCEEKIRLMVSGSAALPL--PVLEKWKNITGHTLLERYGMTEIGMALSGPLTTAVR 373 Query: 377 I-GAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLLIS--------- 426 + G++G + ++ + P R + IH + E G ++ Sbjct: 374 LPGSVG---------TPLPGVQVRIVSENPQREACSYTIHAEGDERGTKVTPGFEEKEGE 424 Query: 427 -RVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTFR 485 V + F Y + TK D + K TGD +V + + D + Sbjct: 425 LLVRGPSVFREYWNKPEETKSAFTLDGWFK------TGDTVVFKDGQYWIRGRTSVDIIK 478 Query: 486 WKGENVATTEVADVIGMLDFIQEANVYGVAISGYEGRAGMASIILKPNTSLDLEKVYEQV 545 G V+ EV + I + V GV + G+ A + L+ SL ++ E Sbjct: 479 TGGYKVSALEVEWHLLAHPSITDVAVIGVPDMTW-GQRVTAVVTLREGHSLSHRELKEWA 537 Query: 546 VTFLPAYACPRFLRIQEKMEATGTFKLLKHQLVEDGFNP 584 L YA P L + E++ K+ K L+ F+P Sbjct: 538 RNVLAPYAVPSELVLVEEIPRNQMGKIDKKALIRH-FHP 575 >gi|13375727 acyl-CoA synthetase short-chain family member 3 [Homo sapiens] Length = 686 Score = 57.8 bits (138), Expect = 3e-08 Identities = 52/200 (26%), Positives = 93/200 (46%), Gaps = 27/200 (13%) Query: 57 LDKFLSHAKRQPRKPFIIYEGDI------YTYQDVDKRSSRVAHVFLNHSSLKKGDTVAL 110 +D+ + + K K IIY+ + +TY++V ++ S++A V + H +KKGDTV + Sbjct: 117 VDRHIENGKGD--KIAIIYDSPVTNTKATFTYKEVLEQVSKLAGVLVKHG-IKKGDTVVI 173 Query: 111 LMSNEPDFVHVWFGLAKLGCVVAFLNTNIRSNSLLNCIRACGPRALVVGADLL--GTVEE 168 M P ++ A++G + + + S L + I P+ +V + + G E Sbjct: 174 YMPMIPQAMYTMLACARIGAIHSLIFGGFASKELSSRIDHVKPKVVVTASFGIEPGRRVE 233 Query: 169 ILPSLSENISVWGMK------------DSVPQGVISLKEKLSTSPDEPVPRSHHVVSLLK 216 +P + E + + K ++VP ++ L + +SH V +L Sbjct: 234 YVPLVEEALKIGQHKPDKILIYNRPNMEAVP---LAPGRDLDWDEEMAKAQSHDCVPVLS 290 Query: 217 STCLYI-FTSGTTGLPKAAV 235 LYI +TSGTTGLPK + Sbjct: 291 EHPLYILYTSGTTGLPKGVI 310 Score = 33.1 bits (74), Expect = 0.78 Identities = 23/98 (23%), Positives = 42/98 (42%), Gaps = 9/98 (9%) Query: 453 FKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTFRWKGENVATTEVADVIGMLDFIQEANVY 512 F+K Y +T D D++ +LY R D G ++ + + I + V Sbjct: 528 FEKFPGYYDTMDAGYMDEEGYLYVMSRVDDVINVAGHRISAGAIEESI-----LSHGTVA 582 Query: 513 GVAISGYE----GRAGMASIILKPNTSLDLEKVYEQVV 546 A+ G E G +A +L+ + + E+V E++V Sbjct: 583 DCAVVGKEDPLKGHVPLALCVLRKDINATEEQVLEEIV 620 >gi|42544134 SA hypertension-associated homolog isoform 2 [Homo sapiens] Length = 438 Score = 53.5 bits (127), Expect = 6e-07 Identities = 70/314 (22%), Positives = 137/314 (43%), Gaps = 19/314 (6%) Query: 80 YTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLAKLGCVVAFLNTNI 139 ++++++ S + A++ SL++GD V L++ P++ + G V+ T + Sbjct: 95 WSFEELGSLSRKFANILSEACSLQRGDRVILILPRVPEWWLANVACLRTGTVLIPGTTQL 154 Query: 140 RSNSLLNCIRACGPRALVVGADLLGTVEEILPSLSENI-SVWGMKDSVPQGVISLKEKLS 198 +L +++ ++ D+L + + S EN+ S + ++ +G +LKE + Sbjct: 155 TQKDILYRLQSSKANCIITN-DVLAPAVDAVASKCENLHSKLIVSENSREGWGNLKELMK 213 Query: 199 TSPDEPVPRSHHVVSLLKSTCLYIF-TSGTTGLPKAAVISQLQVLRGSAVLWAF--GCTA 255 + D SH V + + IF TSGT+G PK + G +V F T Sbjct: 214 HASD-----SHTCVKTKHNEIMAIFFTSGTSGYPKMTAHTHSSFGLGLSVNGRFWLDLTP 268 Query: 256 HDIVYITLPLYHSSAAILGISGCVELGATCVLK---KKFSASQFWSDCKKYDVTVFQYIG 312 D+++ T + +A + GA CV +F + KY +TVF Sbjct: 269 SDVMWNTSDTGWAKSAWSSVFSPWIQGA-CVFTHHLPRFEPTSILQTLSKYPITVFCSAP 327 Query: 313 ELCRYLCKQSKREGE-KDHKVRLAIGNGIRSDVWREFLDRFGNIKVCELYAATESSISFM 371 + R L + + K K ++ G I DV ++ ++ G + + E Y TE+ + Sbjct: 328 TVYRMLVQNDITSYKFKSLKHCVSAGEPITPDVTEKWRNKTG-LDIYEGYGQTETVLICG 386 Query: 372 NYTG---RIGAIGR 382 N+ G + G++G+ Sbjct: 387 NFKGMKIKPGSMGK 400 >gi|8923896 acyl-CoA synthetase short-chain family member 2 isoform 1 [Homo sapiens] Length = 701 Score = 50.1 bits (118), Expect = 6e-06 Identities = 111/517 (21%), Positives = 184/517 (35%), Gaps = 81/517 (15%) Query: 56 VLDKFLSHAKRQPRKPFIIYEGDI------YTYQDVDKRSSRVAHVFLNHSSLKKGDTVA 109 VLD+ + H K+ K +EG+ TY + + + ++V L ++KGD VA Sbjct: 107 VLDRNV-HEKKLGDKVAFYWEGNEPGETTQITYHQLLVQVCQFSNV-LRKQGIQKGDRVA 164 Query: 110 LLMSNEPDFVHVWFGLAKLGCVVAFLNTNIRSNSLLNCI--RACGPRALVVGADLLGTVE 167 + M P+ V A++G + + + S SL I +C +L++ D E Sbjct: 165 IYMPMIPELVVAMLACARIGALHSIVFAGFSSESLCERILDSSC---SLLITTDAFYRGE 221 Query: 168 EI--LPSLSENISVWGMKDSVPQGVISLKEKL---------STSPDEPVPRS-------- 208 ++ L L++ + P + + L STS P+ RS Sbjct: 222 KLVNLKELADEALQKCQEKGFPVRCCIVVKHLGRAELGMGDSTSQSPPIKRSCPDVQISW 281 Query: 209 --------HHVVSLLKSTC-----------LYIFTSGTTGLPKAAV--ISQLQVLRGSAV 247 H ++ C ++TSG+TG PK V + + + Sbjct: 282 NQGIDLWWHELMQEAGDECEPEWCDAEDPLFILYTSGSTGKPKGVVHTVGGYMLYVATTF 341 Query: 248 LWAFGCTAHDIVYITLPLYHSSAAILGISGCVELGATCVLKKKF----SASQFWSDCKKY 303 + F A D+ + T + + G + GAT VL + ++ WS KY Sbjct: 342 KYVFDFHAEDVFWCTADIGWITGHSYVTYGPLANGATSVLFEGIPTYPDVNRLWSIVDKY 401 Query: 304 DVTVFQYIGELCRYLCKQSKREGEKDHKVRL----AIGNGIRSDVWREFLDRFG--NIKV 357 VT F R L K K + L +G I + W + G + Sbjct: 402 KVTKFYTAPTAIRLLMKFGDEPVTKHSRASLQVLGTVGEPINPEAWLWYHRVVGAQRCPI 461 Query: 358 CELYAATESSISFMNYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVK 417 + + TE+ + + +TF F + NE G Sbjct: 462 VDTFWQTETGGHMLT------PLPGATPMKPGSATFPF----FGVAPAILNESG---EEL 508 Query: 418 KGE-PGLLISRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYF 476 +GE G L+ K P+ G ++ FKK Y TGD +DQD + + Sbjct: 509 EGEAEGYLV----FKQPWPGIMRTVYGNHERFETTYFKKFPGYYVTGDGCQRDQDGYYWI 564 Query: 477 WDRTGDTFRWKGENVATTEVADVIGMLDFIQEANVYG 513 R D G ++T EV + + + EA V G Sbjct: 565 TGRIDDMLNVSGHLLSTAEVESALVEHEAVAEAAVVG 601 >gi|253970489 acyl-CoA synthetase short-chain family member 2 isoform 2 [Homo sapiens] Length = 714 Score = 45.1 bits (105), Expect = 2e-04 Identities = 111/530 (20%), Positives = 184/530 (34%), Gaps = 94/530 (17%) Query: 56 VLDKFLSHAKRQPRKPFIIYEGDI------YTYQDVDKRSSRVAHVFLNHSSLKKGDTVA 109 VLD+ + H K+ K +EG+ TY + + + ++V L ++KGD VA Sbjct: 107 VLDRNV-HEKKLGDKVAFYWEGNEPGETTQITYHQLLVQVCQFSNV-LRKQGIQKGDRVA 164 Query: 110 LLMSNEPDFVHVWFGLAKLGCVVAFLNTNIRSNSLLNCI--RACGPRALVVGADLLGTVE 167 + M P+ V A++G + + + S SL I +C +L++ D E Sbjct: 165 IYMPMIPELVVAMLACARIGALHSIVFAGFSSESLCERILDSSC---SLLITTDAFYRGE 221 Query: 168 EI--LPSLSENISVWGMKDSVPQGVISLKEKL---------STSPDEPVPRS-------- 208 ++ L L++ + P + + L STS P+ RS Sbjct: 222 KLVNLKELADEALQKCQEKGFPVRCCIVVKHLGRAELGMGDSTSQSPPIKRSCPDVQGKL 281 Query: 209 ---------------------HHVVSLLKSTC-----------LYIFTSGTTGLPKAAV- 235 H ++ C ++TSG+TG PK V Sbjct: 282 KEKSKRVQPQISWNQGIDLWWHELMQEAGDECEPEWCDAEDPLFILYTSGSTGKPKGVVH 341 Query: 236 -ISQLQVLRGSAVLWAFGCTAHDIVYITLPLYHSSAAILGISGCVELGATCVLKKKF--- 291 + + + + F A D+ + T + + G + GAT VL + Sbjct: 342 TVGGYMLYVATTFKYVFDFHAEDVFWCTADIGWITGHSYVTYGPLANGATSVLFEGIPTY 401 Query: 292 -SASQFWSDCKKYDVTVFQYIGELCRYLCKQSKREGEKDHKVRL----AIGNGIRSDVWR 346 ++ WS KY VT F R L K K + L +G I + W Sbjct: 402 PDVNRLWSIVDKYKVTKFYTAPTAIRLLMKFGDEPVTKHSRASLQVLGTVGEPINPEAWL 461 Query: 347 EFLDRFG--NIKVCELYAATESSISFMNYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDE 404 + G + + + TE+ + + +TF F Sbjct: 462 WYHRVVGAQRCPIVDTFWQTETGGHMLT------PLPGATPMKPGSATFPF----FGVAP 511 Query: 405 PMRNEQGWCIHVKKGE-PGLLISRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTG 463 + NE G +GE G L+ K P+ G ++ FKK Y TG Sbjct: 512 AILNESG---EELEGEAEGYLV----FKQPWPGIMRTVYGNHERFETTYFKKFPGYYVTG 564 Query: 464 DLIVQDQDNFLYFWDRTGDTFRWKGENVATTEVADVIGMLDFIQEANVYG 513 D +DQD + + R D G ++T EV + + + EA V G Sbjct: 565 DGCQRDQDGYYWITGRIDDMLNVSGHLLSTAEVESALVEHEAVAEAAVVG 614 >gi|156151445 acyl-CoA synthetase family member 2 [Homo sapiens] Length = 615 Score = 42.4 bits (98), Expect = 0.001 Identities = 53/232 (22%), Positives = 95/232 (40%), Gaps = 34/232 (14%) Query: 83 QDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLAKLGCVVAFLNTNIRSN 142 ++VDK +S + + L KGD + + N +V + A+ G ++ +N ++ Sbjct: 107 EEVDKAASGLLSI-----GLCKGDRLGMWGPNSYAWVLMQLATAQAGIILVSVNPAYQAM 161 Query: 143 SLLNCIRACGPRALVVGADL-----LGTVEEILPSLSENISVWGMK-------------D 184 L ++ G +ALV +++I P + EN +K D Sbjct: 162 ELEYVLKKVGCKALVFPKQFKTQQYYNVLKQICPEV-ENAQPGALKSQRLPDLTTVISVD 220 Query: 185 SVPQGVISLKEKLST-SPDEPVPRSHHVVSLLK--STCLYIFTSGTTGLPKAAVISQLQV 241 + G + L E ++ S + + + + L FTSGTTG PK A +S + Sbjct: 221 APLPGTLLLDEVVAAGSTRQHLDQLQYNQQFLSCHDPINIQFTSGTTGSPKGATLSHYNI 280 Query: 242 LRGSAVLWAFGCTAHD------IVYITLPLYHSSAAILGISGCVELGATCVL 287 + S +L H+ + + PLYH ++ G C+ GAT +L Sbjct: 281 VNNSNIL-GERLKLHEKTPEQLRMILPNPLYHCLGSVAGTMMCLMYGATLIL 331 Score = 32.0 bits (71), Expect = 1.7 Identities = 29/123 (23%), Positives = 48/123 (39%), Gaps = 1/123 (0%) Query: 457 DVYLNTGDLIVQDQDNFLYFWDRTGDTFRWKGENVATTEVADVIGMLDFIQEANVYGVAI 516 D + TGD+ ++ F R+ D GEN+ E+ D +QE V GV Sbjct: 486 DKWYWTGDVATMNEQGFCKIVGRSKDMIIRGGENIYPAELEDFFHTHPKVQEVQVVGVK- 544 Query: 517 SGYEGRAGMASIILKPNTSLDLEKVYEQVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQ 576 G A I LK +E++ + + P+++ T + K+ K + Sbjct: 545 DDRMGEEICACIRLKDGEETTVEEIKAFCKGKISHFKIPKYIVFVTNYPLTISGKIQKFK 604 Query: 577 LVE 579 L E Sbjct: 605 LRE 607 >gi|195947378 acyl-coenzyme A synthetase ACSM6, mitochondrial [Homo sapiens] Length = 480 Score = 42.0 bits (97), Expect = 0.002 Identities = 81/428 (18%), Positives = 160/428 (37%), Gaps = 41/428 (9%) Query: 76 EGDIYTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLAKLGCVVAFL 135 E D ++++ + + S + A + + +L GD + +++ P+ + +LG Sbjct: 82 EEDKWSFERMTQLSKKAASILSDTCALSHGDRLMIILPPTPEAYWICLACVRLGITFVPG 141 Query: 136 NTNIRSNSLLNCIRACGPRALVVG---ADLLGTVEEILPSLSENISVWGMKDSVPQGVIS 192 + + + + +R + +V A ++ + P+L + V D G + Sbjct: 142 SPQLTAKKIRYQLRMSKAQCIVANEAMAPVVNSAVSDCPTLKTKLLV---SDKSYDGWLD 198 Query: 193 LKEKLSTSPDEPVPRSHHVVSLLKSTCLYIFTSGTTGLPKAAVISQLQVLRG---SAVLW 249 K+ + +P P+ ++ + + FT GTTG PK SQ + G ++ W Sbjct: 199 FKKLIQVAP----PKQTYMRTKSQDPMAIFFTKGTTGAPKMVEYSQYGLGMGFSQASRRW 254 Query: 250 AFGCTAHDIVYITLPLYHSSAAILGISGCVELGATCVL--KKKFSASQFWSDCKKYDVTV 307 D+++ + S ++ + G GA L F + ++ +T Sbjct: 255 -MDLQPTDVLWSLGDAFGGSLSLSAVLGTWFQGACVFLCHMPTFCPETVLNVLSRFPITT 313 Query: 308 F----QYIGELCRYLCKQSKREGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVCELYAA 363 + EL ++ C S R K K +A G I V ++ R + + E Y Sbjct: 314 LSANPEMYQELLQHKCFTSYR--FKSLKQCVAAGGPISPGVIEDW-KRITKLDIYEGYGQ 370 Query: 364 TESSISFMNYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGL 423 TE TG + A +T L Y Q + N + GE G Sbjct: 371 TE--------TGLLCATSKTIKLKPSSLGKPLPPYIVQIVDENSN------LLPPGEEGN 416 Query: 424 LISRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDT 483 + R+ P Y P+ + ++ +G + TGD + D+D + ++ R D Sbjct: 417 IAIRIKLNQPASLYC-PHMVSWEEY---ASARGHMLYLTGDRGIMDEDGYFWWSGRVDDV 472 Query: 484 FRWKGENV 491 G+ + Sbjct: 473 ANALGQRL 480 >gi|27477105 lipidosin [Homo sapiens] Length = 724 Score = 40.0 bits (92), Expect = 0.006 Identities = 51/210 (24%), Positives = 84/210 (40%), Gaps = 24/210 (11%) Query: 91 RVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLAKLGCVVAFLNTNIRSNSLLNCIRA 150 R A FL LK+ +VA+L N P++ G G +V + T + Sbjct: 144 RAAKGFLK-LGLKQAHSVAILGFNSPEWFFSAVGTVFAGGIVTGIYTTSSPEACQYIAYD 202 Query: 151 CGPRALVVGADL-LGTVEEILPSLSENISVWGMKDSVPQ---GVISLKEKLSTSPDEPVP 206 C ++V L + +I L +V K+ P V +++E + + P Sbjct: 203 CCANVIMVDTQKQLEKILKIWKQLPHLKAVVIYKEPPPNKMANVYTMEEFMELGNEVPEE 262 Query: 207 RSHHVVSLLKST--CLYIFTSGTTGLPKAAVISQLQVLRGSAVLWA--FGCTAHDI---- 258 ++ + C+ ++TSGTTG PK ++SQ + W +G A DI Sbjct: 263 ALDAIIDTQQPNQCCVLVYTSGTTGNPKGVMLSQ------DNITWTARYGSQAGDIRPAE 316 Query: 259 -----VYITLPLYHSSAAILGISGCVELGA 283 V LPL H +A I + ++ GA Sbjct: 317 VQQEVVVSYLPLSHIAAQIYDLWTGIQWGA 346 Score = 29.6 bits (65), Expect = 8.6 Identities = 31/115 (26%), Positives = 52/115 (45%), Gaps = 15/115 (13%) Query: 441 YKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGD-TFRWKGENVATTEVADV 499 Y + +DK + ++G +L+TGD D D FLY R + GENV + + Sbjct: 529 YLNMEDKTCEAIDEEG--WLHTGDAGRLDADGFLYITGRLKELIITAGGENVPPVPIEEA 586 Query: 500 IGM-LDFIQEANVYGVAISGYEGRAGMASII-----LKPNTSLDLEKVYEQVVTF 548 + M L I A + G + R ++ ++ L P+TS + + EQ + F Sbjct: 587 VKMELPIISNAMLIG------DQRKFLSMLLTLKCTLDPDTSDQTDNLTEQAMEF 635 >gi|42794760 acyl-CoA synthetase long-chain family member 5 isoform b [Homo sapiens] Length = 683 Score = 37.4 bits (85), Expect = 0.041 Identities = 50/224 (22%), Positives = 90/224 (40%), Gaps = 33/224 (14%) Query: 66 RQPRKPFIIYEGDIYTYQDVDKRSSRVAHVFLNHSSLKKGDT-VALLMSNEPDFVHVWFG 124 R+P +P+ +Y+ V R+ + L+ D V + N P+++ Sbjct: 97 RKPNQPY-----RWLSYKQVSDRAEYLGSCLLHKGYKSSPDQFVGIFAQNRPEWIISELA 151 Query: 125 LAKLGCVVAFLNTNIRSNSLLNCIRACGPRALVVGAD-----LLGTVEE-ILPSLSENIS 178 V L + ++++ + ++ L+G VE+ PSL I Sbjct: 152 CYTYSMVAVPLYDTLGPEAIVHIVNKADIAMVICDTPQKALVLIGNVEKGFTPSLKVIIL 211 Query: 179 VWGMKDSVPQG-------VISLKEKLSTSPD---EPVPRSHHVVSLLKSTCLYIFTSGTT 228 + D + Q ++SL + + + +PVP S +S++ FTSGTT Sbjct: 212 MDPFDDDLKQRGEKSGIEILSLYDAENLGKEHFRKPVPPSPEDLSVI------CFTSGTT 265 Query: 229 GLPKAAVISQLQVLRGSA-----VLWAFGCTAHDIVYITLPLYH 267 G PK A+I+ ++ +A V A+ T D+ LPL H Sbjct: 266 GDPKGAMITHQNIVSNAAAFLKCVEHAYEPTPDDVAISYLPLAH 309 >gi|42794758 acyl-CoA synthetase long-chain family member 5 isoform b [Homo sapiens] Length = 683 Score = 37.4 bits (85), Expect = 0.041 Identities = 50/224 (22%), Positives = 90/224 (40%), Gaps = 33/224 (14%) Query: 66 RQPRKPFIIYEGDIYTYQDVDKRSSRVAHVFLNHSSLKKGDT-VALLMSNEPDFVHVWFG 124 R+P +P+ +Y+ V R+ + L+ D V + N P+++ Sbjct: 97 RKPNQPY-----RWLSYKQVSDRAEYLGSCLLHKGYKSSPDQFVGIFAQNRPEWIISELA 151 Query: 125 LAKLGCVVAFLNTNIRSNSLLNCIRACGPRALVVGAD-----LLGTVEE-ILPSLSENIS 178 V L + ++++ + ++ L+G VE+ PSL I Sbjct: 152 CYTYSMVAVPLYDTLGPEAIVHIVNKADIAMVICDTPQKALVLIGNVEKGFTPSLKVIIL 211 Query: 179 VWGMKDSVPQG-------VISLKEKLSTSPD---EPVPRSHHVVSLLKSTCLYIFTSGTT 228 + D + Q ++SL + + + +PVP S +S++ FTSGTT Sbjct: 212 MDPFDDDLKQRGEKSGIEILSLYDAENLGKEHFRKPVPPSPEDLSVI------CFTSGTT 265 Query: 229 GLPKAAVISQLQVLRGSA-----VLWAFGCTAHDIVYITLPLYH 267 G PK A+I+ ++ +A V A+ T D+ LPL H Sbjct: 266 GDPKGAMITHQNIVSNAAAFLKCVEHAYEPTPDDVAISYLPLAH 309 >gi|42794756 acyl-CoA synthetase long-chain family member 5 isoform a [Homo sapiens] Length = 739 Score = 37.4 bits (85), Expect = 0.041 Identities = 50/224 (22%), Positives = 90/224 (40%), Gaps = 33/224 (14%) Query: 66 RQPRKPFIIYEGDIYTYQDVDKRSSRVAHVFLNHSSLKKGDT-VALLMSNEPDFVHVWFG 124 R+P +P+ +Y+ V R+ + L+ D V + N P+++ Sbjct: 153 RKPNQPY-----RWLSYKQVSDRAEYLGSCLLHKGYKSSPDQFVGIFAQNRPEWIISELA 207 Query: 125 LAKLGCVVAFLNTNIRSNSLLNCIRACGPRALVVGAD-----LLGTVEE-ILPSLSENIS 178 V L + ++++ + ++ L+G VE+ PSL I Sbjct: 208 CYTYSMVAVPLYDTLGPEAIVHIVNKADIAMVICDTPQKALVLIGNVEKGFTPSLKVIIL 267 Query: 179 VWGMKDSVPQG-------VISLKEKLSTSPD---EPVPRSHHVVSLLKSTCLYIFTSGTT 228 + D + Q ++SL + + + +PVP S +S++ FTSGTT Sbjct: 268 MDPFDDDLKQRGEKSGIEILSLYDAENLGKEHFRKPVPPSPEDLSVI------CFTSGTT 321 Query: 229 GLPKAAVISQLQVLRGSA-----VLWAFGCTAHDIVYITLPLYH 267 G PK A+I+ ++ +A V A+ T D+ LPL H Sbjct: 322 GDPKGAMITHQNIVSNAAAFLKCVEHAYEPTPDDVAISYLPLAH 365 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.323 0.140 0.429 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 22,207,007 Number of Sequences: 37866 Number of extensions: 961339 Number of successful extensions: 2096 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 24 Number of HSP's successfully gapped in prelim test: 27 Number of HSP's that attempted gapping in prelim test: 2031 Number of HSP's gapped (non-prelim): 69 length of query: 619 length of database: 18,247,518 effective HSP length: 108 effective length of query: 511 effective length of database: 14,157,990 effective search space: 7234732890 effective search space used: 7234732890 T: 11 A: 40 X1: 16 ( 7.5 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (22.0 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.