Guide to the Human Genome
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Search of human proteins with 62865631

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|62865631 solute carrier family 27 (fatty acid transporter),
member 6 [Homo sapiens]
         (619 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|62865631 solute carrier family 27 (fatty acid transporter), m...  1255   0.0  
gi|13325055 solute carrier family 27 (fatty acid transporter), m...  1255   0.0  
gi|227499619 solute carrier family 27 (fatty acid transporter), ...   648   0.0  
gi|227499621 solute carrier family 27 (fatty acid transporter), ...   571   e-163
gi|13236579 solute carrier family 27 member 3 [Homo sapiens]          518   e-147
gi|13325057 solute carrier family 27 (fatty acid transporter), m...   497   e-140
gi|40807357 solute carrier family 27 (fatty acid transporter), m...   422   e-118
gi|38524616 solute carrier family 27, member 1 [Homo sapiens]         410   e-114
gi|28416953 acyl-CoA synthetase short-chain family member 1 [Hom...    69   1e-11
gi|42544132 SA hypertension-associated homolog isoform 1 [Homo s...    67   5e-11
gi|122937307 acyl-CoA synthetase medium-chain family member 4 [H...    64   3e-10
gi|157311624 acyl-CoA synthetase medium-chain family member 2B [...    64   4e-10
gi|157311622 acyl-CoA synthetase medium-chain family member 2B [...    64   4e-10
gi|38505220 acyl-CoA synthetase medium-chain family member 5 [Ho...    62   2e-09
gi|115511026 acyl-CoA synthetase medium-chain family member 1 [H...    62   2e-09
gi|239756507 PREDICTED: similar to Acyl-coenzyme A synthetase AC...    61   3e-09
gi|239756505 PREDICTED: similar to Acyl-coenzyme A synthetase AC...    61   3e-09
gi|58082049 acyl-CoA synthetase medium-chain family member 2A [H...    60   6e-09
gi|187761345 acyl-CoA synthetase family member 3 [Homo sapiens]        60   8e-09
gi|187761343 acyl-CoA synthetase family member 3 [Homo sapiens]        60   8e-09
gi|13375727 acyl-CoA synthetase short-chain family member 3 [Hom...    58   3e-08
gi|42544134 SA hypertension-associated homolog isoform 2 [Homo s...    54   6e-07
gi|8923896 acyl-CoA synthetase short-chain family member 2 isofo...    50   6e-06
gi|253970489 acyl-CoA synthetase short-chain family member 2 iso...    45   2e-04
gi|156151445 acyl-CoA synthetase family member 2 [Homo sapiens]        42   0.001
gi|195947378 acyl-coenzyme A synthetase ACSM6, mitochondrial [Ho...    42   0.002
gi|27477105 lipidosin [Homo sapiens]                                   40   0.006
gi|42794760 acyl-CoA synthetase long-chain family member 5 isofo...    37   0.041
gi|42794758 acyl-CoA synthetase long-chain family member 5 isofo...    37   0.041
gi|42794756 acyl-CoA synthetase long-chain family member 5 isofo...    37   0.041

>gi|62865631 solute carrier family 27 (fatty acid transporter),
           member 6 [Homo sapiens]
          Length = 619

 Score = 1255 bits (3247), Expect = 0.0
 Identities = 619/619 (100%), Positives = 619/619 (100%)

Query: 1   MLLSWLTVLGAGMVVLHFLQKLLFPYFWDDFWFVLKVVLIIIRLKKYEKRGELVTVLDKF 60
           MLLSWLTVLGAGMVVLHFLQKLLFPYFWDDFWFVLKVVLIIIRLKKYEKRGELVTVLDKF
Sbjct: 1   MLLSWLTVLGAGMVVLHFLQKLLFPYFWDDFWFVLKVVLIIIRLKKYEKRGELVTVLDKF 60

Query: 61  LSHAKRQPRKPFIIYEGDIYTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVH 120
           LSHAKRQPRKPFIIYEGDIYTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVH
Sbjct: 61  LSHAKRQPRKPFIIYEGDIYTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVH 120

Query: 121 VWFGLAKLGCVVAFLNTNIRSNSLLNCIRACGPRALVVGADLLGTVEEILPSLSENISVW 180
           VWFGLAKLGCVVAFLNTNIRSNSLLNCIRACGPRALVVGADLLGTVEEILPSLSENISVW
Sbjct: 121 VWFGLAKLGCVVAFLNTNIRSNSLLNCIRACGPRALVVGADLLGTVEEILPSLSENISVW 180

Query: 181 GMKDSVPQGVISLKEKLSTSPDEPVPRSHHVVSLLKSTCLYIFTSGTTGLPKAAVISQLQ 240
           GMKDSVPQGVISLKEKLSTSPDEPVPRSHHVVSLLKSTCLYIFTSGTTGLPKAAVISQLQ
Sbjct: 181 GMKDSVPQGVISLKEKLSTSPDEPVPRSHHVVSLLKSTCLYIFTSGTTGLPKAAVISQLQ 240

Query: 241 VLRGSAVLWAFGCTAHDIVYITLPLYHSSAAILGISGCVELGATCVLKKKFSASQFWSDC 300
           VLRGSAVLWAFGCTAHDIVYITLPLYHSSAAILGISGCVELGATCVLKKKFSASQFWSDC
Sbjct: 241 VLRGSAVLWAFGCTAHDIVYITLPLYHSSAAILGISGCVELGATCVLKKKFSASQFWSDC 300

Query: 301 KKYDVTVFQYIGELCRYLCKQSKREGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVCEL 360
           KKYDVTVFQYIGELCRYLCKQSKREGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVCEL
Sbjct: 301 KKYDVTVFQYIGELCRYLCKQSKREGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVCEL 360

Query: 361 YAATESSISFMNYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGE 420
           YAATESSISFMNYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGE
Sbjct: 361 YAATESSISFMNYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGE 420

Query: 421 PGLLISRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRT 480
           PGLLISRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRT
Sbjct: 421 PGLLISRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRT 480

Query: 481 GDTFRWKGENVATTEVADVIGMLDFIQEANVYGVAISGYEGRAGMASIILKPNTSLDLEK 540
           GDTFRWKGENVATTEVADVIGMLDFIQEANVYGVAISGYEGRAGMASIILKPNTSLDLEK
Sbjct: 481 GDTFRWKGENVATTEVADVIGMLDFIQEANVYGVAISGYEGRAGMASIILKPNTSLDLEK 540

Query: 541 VYEQVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQLVEDGFNPLKISEPLYFMDNLKKS 600
           VYEQVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQLVEDGFNPLKISEPLYFMDNLKKS
Sbjct: 541 VYEQVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQLVEDGFNPLKISEPLYFMDNLKKS 600

Query: 601 YVLLTRELYDQIMLGEIKL 619
           YVLLTRELYDQIMLGEIKL
Sbjct: 601 YVLLTRELYDQIMLGEIKL 619


>gi|13325055 solute carrier family 27 (fatty acid transporter),
           member 6 [Homo sapiens]
          Length = 619

 Score = 1255 bits (3247), Expect = 0.0
 Identities = 619/619 (100%), Positives = 619/619 (100%)

Query: 1   MLLSWLTVLGAGMVVLHFLQKLLFPYFWDDFWFVLKVVLIIIRLKKYEKRGELVTVLDKF 60
           MLLSWLTVLGAGMVVLHFLQKLLFPYFWDDFWFVLKVVLIIIRLKKYEKRGELVTVLDKF
Sbjct: 1   MLLSWLTVLGAGMVVLHFLQKLLFPYFWDDFWFVLKVVLIIIRLKKYEKRGELVTVLDKF 60

Query: 61  LSHAKRQPRKPFIIYEGDIYTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVH 120
           LSHAKRQPRKPFIIYEGDIYTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVH
Sbjct: 61  LSHAKRQPRKPFIIYEGDIYTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVH 120

Query: 121 VWFGLAKLGCVVAFLNTNIRSNSLLNCIRACGPRALVVGADLLGTVEEILPSLSENISVW 180
           VWFGLAKLGCVVAFLNTNIRSNSLLNCIRACGPRALVVGADLLGTVEEILPSLSENISVW
Sbjct: 121 VWFGLAKLGCVVAFLNTNIRSNSLLNCIRACGPRALVVGADLLGTVEEILPSLSENISVW 180

Query: 181 GMKDSVPQGVISLKEKLSTSPDEPVPRSHHVVSLLKSTCLYIFTSGTTGLPKAAVISQLQ 240
           GMKDSVPQGVISLKEKLSTSPDEPVPRSHHVVSLLKSTCLYIFTSGTTGLPKAAVISQLQ
Sbjct: 181 GMKDSVPQGVISLKEKLSTSPDEPVPRSHHVVSLLKSTCLYIFTSGTTGLPKAAVISQLQ 240

Query: 241 VLRGSAVLWAFGCTAHDIVYITLPLYHSSAAILGISGCVELGATCVLKKKFSASQFWSDC 300
           VLRGSAVLWAFGCTAHDIVYITLPLYHSSAAILGISGCVELGATCVLKKKFSASQFWSDC
Sbjct: 241 VLRGSAVLWAFGCTAHDIVYITLPLYHSSAAILGISGCVELGATCVLKKKFSASQFWSDC 300

Query: 301 KKYDVTVFQYIGELCRYLCKQSKREGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVCEL 360
           KKYDVTVFQYIGELCRYLCKQSKREGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVCEL
Sbjct: 301 KKYDVTVFQYIGELCRYLCKQSKREGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVCEL 360

Query: 361 YAATESSISFMNYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGE 420
           YAATESSISFMNYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGE
Sbjct: 361 YAATESSISFMNYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGE 420

Query: 421 PGLLISRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRT 480
           PGLLISRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRT
Sbjct: 421 PGLLISRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRT 480

Query: 481 GDTFRWKGENVATTEVADVIGMLDFIQEANVYGVAISGYEGRAGMASIILKPNTSLDLEK 540
           GDTFRWKGENVATTEVADVIGMLDFIQEANVYGVAISGYEGRAGMASIILKPNTSLDLEK
Sbjct: 481 GDTFRWKGENVATTEVADVIGMLDFIQEANVYGVAISGYEGRAGMASIILKPNTSLDLEK 540

Query: 541 VYEQVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQLVEDGFNPLKISEPLYFMDNLKKS 600
           VYEQVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQLVEDGFNPLKISEPLYFMDNLKKS
Sbjct: 541 VYEQVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQLVEDGFNPLKISEPLYFMDNLKKS 600

Query: 601 YVLLTRELYDQIMLGEIKL 619
           YVLLTRELYDQIMLGEIKL
Sbjct: 601 YVLLTRELYDQIMLGEIKL 619


>gi|227499619 solute carrier family 27 (fatty acid transporter),
           member 2 isoform 1 [Homo sapiens]
          Length = 620

 Score =  648 bits (1672), Expect = 0.0
 Identities = 316/621 (50%), Positives = 431/621 (69%), Gaps = 3/621 (0%)

Query: 1   MLLSWLTVLGAGMVVLHFLQKLLFPYFWDDFWFVLKVVLIIIRLKKYEKRGELVTVLDKF 60
           ML +  TVL AG++ L  L  L  PYF+ D  + LKV  +  R++ Y KR    T+L  F
Sbjct: 1   MLSAIYTVL-AGLLFLPLLVNLCCPYFFQDIGYFLKVAAVGRRVRSYGKRRPARTILRAF 59

Query: 61  LSHAKRQPRKPFIIYEGDIYTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVH 120
           L  A++ P KPF+++  +  TY  VD+RS++VA    +H  L++GD VALLM NEP +V 
Sbjct: 60  LEKARQTPHKPFLLFRDETLTYAQVDRRSNQVARALHDHLGLRQGDCVALLMGNEPAYVW 119

Query: 121 VWFGLAKLGCVVAFLNTNIRSNSLLNCIRACGPRALVVGADLLGTVEEILPSLS-ENISV 179
           +W GL KLGC +A LN NIR+ SLL+C + CG + L+V  +L   VEEILPSL  +++S+
Sbjct: 120 LWLGLVKLGCAMACLNYNIRAKSLLHCFQCCGAKVLLVSPELQAAVEEILPSLKKDDVSI 179

Query: 180 WGM-KDSVPQGVISLKEKLSTSPDEPVPRSHHVVSLLKSTCLYIFTSGTTGLPKAAVISQ 238
           + + + S   G+ S  +K+     EP+P S        +  LYI+TSGTTGLPKAA+I+ 
Sbjct: 180 YYVSRTSNTDGIDSFLDKVDEVSTEPIPESWRSEVTFSTPALYIYTSGTTGLPKAAMITH 239

Query: 239 LQVLRGSAVLWAFGCTAHDIVYITLPLYHSSAAILGISGCVELGATCVLKKKFSASQFWS 298
            ++  G+ + +  G  A D++YITLP YHS+A ++GI GC+  GAT  L+ KFSASQFW 
Sbjct: 240 QRIWYGTGLTFVSGLKADDVIYITLPFYHSAALLIGIHGCIVAGATLALRTKFSASQFWD 299

Query: 299 DCKKYDVTVFQYIGELCRYLCKQSKREGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVC 358
           DC+KY+VTV QYIGEL RYLC   ++  ++DHKVRLA+GNG+R DVWR+F+ RFG+I + 
Sbjct: 300 DCRKYNVTVIQYIGELLRYLCNSPQKPNDRDHKVRLALGNGLRGDVWRQFVKRFGDICIY 359

Query: 359 ELYAATESSISFMNYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKK 418
           E YAATE +I FMNY  ++GA+GR N   K + T+DLIKYD +KDEP+R+E G+C+ V K
Sbjct: 360 EFYAATEGNIGFMNYARKVGAVGRVNYLQKKIITYDLIKYDVEKDEPVRDENGYCVRVPK 419

Query: 419 GEPGLLISRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWD 478
           GE GLL+ ++    PF GYAG    T+ K L DVFKKGD+Y N+GDL++ D +NF+YF D
Sbjct: 420 GEVGLLVCKITQLTPFNGYAGAKAQTEKKKLRDVFKKGDLYFNSGDLLMVDHENFIYFHD 479

Query: 479 RTGDTFRWKGENVATTEVADVIGMLDFIQEANVYGVAISGYEGRAGMASIILKPNTSLDL 538
           R GDTFRWKGENVATTEVAD +G++DF+QE NVYGV +  +EGR GMASI +K N   D 
Sbjct: 480 RVGDTFRWKGENVATTEVADTVGLVDFVQEVNVYGVHVPDHEGRIGMASIKMKENHEFDG 539

Query: 539 EKVYEQVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQLVEDGFNPLKISEPLYFMDNLK 598
           +K+++ +  +LP+YA PRFLRIQ+ +E TGTFK  K  LVE+GFNP  I + LYF+D+  
Sbjct: 540 KKLFQHIADYLPSYARPRFLRIQDTIEITGTFKHRKMTLVEEGFNPAVIKDALYFLDDTA 599

Query: 599 KSYVLLTRELYDQIMLGEIKL 619
           K YV +T ++Y+ I    +KL
Sbjct: 600 KMYVPMTEDIYNAISAKTLKL 620


>gi|227499621 solute carrier family 27 (fatty acid transporter),
           member 2 isoform 2 [Homo sapiens]
          Length = 567

 Score =  571 bits (1471), Expect = e-163
 Identities = 292/621 (47%), Positives = 394/621 (63%), Gaps = 56/621 (9%)

Query: 1   MLLSWLTVLGAGMVVLHFLQKLLFPYFWDDFWFVLKVVLIIIRLKKYEKRGELVTVLDKF 60
           ML +  TVL AG++ L  L  L  PYF+ D  + LKV  +  R++ Y KR    T+L  F
Sbjct: 1   MLSAIYTVL-AGLLFLPLLVNLCCPYFFQDIGYFLKVAAVGRRVRSYGKRRPARTILRAF 59

Query: 61  LSHAKRQPRKPFIIYEGDIYTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVH 120
           L  A++ P KPF+++  +  TY  VD+RS++VA    +H  L++GD VALLM NEP +V 
Sbjct: 60  LEKARQTPHKPFLLFRDETLTYAQVDRRSNQVARALHDHLGLRQGDCVALLMGNEPAYVW 119

Query: 121 VWFGLAKLGCVVAFLNTNIRSNSLLNCIRACGPRALVVGADLLGTVEEILPSLS-ENISV 179
           +W GL KLGC +A LN NIR+ SLL+C + CG + L+V  +L   VEEILPSL  +++S+
Sbjct: 120 LWLGLVKLGCAMACLNYNIRAKSLLHCFQCCGAKVLLVSPELQAAVEEILPSLKKDDVSI 179

Query: 180 WGM-KDSVPQGVISLKEKLSTSPDEPVPRSHHVVSLLKSTCLYIFTSGTTGLPKAAVISQ 238
           + + + S   G+ S  +K+     EP+P S        +  LYI+TSGTT          
Sbjct: 180 YYVSRTSNTDGIDSFLDKVDEVSTEPIPESWRSEVTFSTPALYIYTSGTT---------- 229

Query: 239 LQVLRGSAVLWAFGCTAHDIVYITLPLYHSSAAILGISGCVELGATCVLKKKFSASQFWS 298
                                                      GAT  L+ KFSASQFW 
Sbjct: 230 -------------------------------------------GATLALRTKFSASQFWD 246

Query: 299 DCKKYDVTVFQYIGELCRYLCKQSKREGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVC 358
           DC+KY+VTV QYIGEL RYLC   ++  ++DHKVRLA+GNG+R DVWR+F+ RFG+I + 
Sbjct: 247 DCRKYNVTVIQYIGELLRYLCNSPQKPNDRDHKVRLALGNGLRGDVWRQFVKRFGDICIY 306

Query: 359 ELYAATESSISFMNYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKK 418
           E YAATE +I FMNY  ++GA+GR N   K + T+DLIKYD +KDEP+R+E G+C+ V K
Sbjct: 307 EFYAATEGNIGFMNYARKVGAVGRVNYLQKKIITYDLIKYDVEKDEPVRDENGYCVRVPK 366

Query: 419 GEPGLLISRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWD 478
           GE GLL+ ++    PF GYAG    T+ K L DVFKKGD+Y N+GDL++ D +NF+YF D
Sbjct: 367 GEVGLLVCKITQLTPFNGYAGAKAQTEKKKLRDVFKKGDLYFNSGDLLMVDHENFIYFHD 426

Query: 479 RTGDTFRWKGENVATTEVADVIGMLDFIQEANVYGVAISGYEGRAGMASIILKPNTSLDL 538
           R GDTFRWKGENVATTEVAD +G++DF+QE NVYGV +  +EGR GMASI +K N   D 
Sbjct: 427 RVGDTFRWKGENVATTEVADTVGLVDFVQEVNVYGVHVPDHEGRIGMASIKMKENHEFDG 486

Query: 539 EKVYEQVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQLVEDGFNPLKISEPLYFMDNLK 598
           +K+++ +  +LP+YA PRFLRIQ+ +E TGTFK  K  LVE+GFNP  I + LYF+D+  
Sbjct: 487 KKLFQHIADYLPSYARPRFLRIQDTIEITGTFKHRKMTLVEEGFNPAVIKDALYFLDDTA 546

Query: 599 KSYVLLTRELYDQIMLGEIKL 619
           K YV +T ++Y+ I    +KL
Sbjct: 547 KMYVPMTEDIYNAISAKTLKL 567


>gi|13236579 solute carrier family 27 member 3 [Homo sapiens]
          Length = 730

 Score =  518 bits (1334), Expect = e-147
 Identities = 258/520 (49%), Positives = 349/520 (67%), Gaps = 2/520 (0%)

Query: 102 LKKGDTVALLMSNEPDFVHVWFGLAKLGCVVAFLNTNIRSNSLLNCIRACGPRALVVGAD 161
           L  G TVALL+   P+F+ +WFGLAK G   AF+ T +R   LL+C+R+CG RALV+  +
Sbjct: 211 LSPGATVALLLPAGPEFLWLWFGLAKAGLRTAFVPTALRRGPLLHCLRSCGARALVLAPE 270

Query: 162 LLGTVEEILPSL-SENISVWGMKDSV-PQGVISLKEKLSTSPDEPVPRSHHVVSLLKSTC 219
            L ++E  LP+L +  + +W       P G+  L  ++S   D PVP        +  TC
Sbjct: 271 FLESLEPDLPALRAMGLHLWAAGPGTHPAGISDLLAEVSAEVDGPVPGYLSSPQSITDTC 330

Query: 220 LYIFTSGTTGLPKAAVISQLQVLRGSAVLWAFGCTAHDIVYITLPLYHSSAAILGISGCV 279
           LYIFTSGTTGLPKAA IS L++L+        G    D++Y+ LPLYH S ++LGI GC+
Sbjct: 331 LYIFTSGTTGLPKAARISHLKILQCQGFYQLCGVHQEDVIYLALPLYHMSGSLLGIVGCM 390

Query: 280 ELGATCVLKKKFSASQFWSDCKKYDVTVFQYIGELCRYLCKQSKREGEKDHKVRLAIGNG 339
            +GAT VLK KFSA QFW DC+++ VTVFQYIGELCRYL  Q   + E+ HKVRLA+G+G
Sbjct: 391 GIGATVVLKSKFSAGQFWEDCQQHRVTVFQYIGELCRYLVNQPPSKAERGHKVRLAVGSG 450

Query: 340 IRSDVWREFLDRFGNIKVCELYAATESSISFMNYTGRIGAIGRTNLFYKLLSTFDLIKYD 399
           +R D W  F+ RFG ++V E Y  TE +++ +NYTG+ GA+GR +  YK +  F LI+YD
Sbjct: 451 LRPDTWERFVRRFGPLQVLETYGLTEGNVATINYTGQRGAVGRASWLYKHIFPFSLIRYD 510

Query: 400 FQKDEPMRNEQGWCIHVKKGEPGLLISRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVY 459
               EP+R+ QG C+    GEPGLL++ V+ ++PF GYAG  +  + KLL DVF+ GDV+
Sbjct: 511 VTTGEPIRDPQGHCMATSPGEPGLLVAPVSQQSPFLGYAGGPELAQGKLLKDVFRPGDVF 570

Query: 460 LNTGDLIVQDQDNFLYFWDRTGDTFRWKGENVATTEVADVIGMLDFIQEANVYGVAISGY 519
            NTGDL+V D   FL F DRTGDTFRWKGENVATTEVA+V   LDF+QE NVYGV + G+
Sbjct: 571 FNTGDLLVCDDQGFLRFHDRTGDTFRWKGENVATTEVAEVFEALDFLQEVNVYGVTVPGH 630

Query: 520 EGRAGMASIILKPNTSLDLEKVYEQVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQLVE 579
           EGRAGMA+++L+P  +LDL ++Y  V   LP YA PRFLR+QE +  T TFK  K ++  
Sbjct: 631 EGRAGMAALVLRPPHALDLMQLYTHVSENLPPYARPRFLRLQESLATTETFKQQKVRMAN 690

Query: 580 DGFNPLKISEPLYFMDNLKKSYVLLTRELYDQIMLGEIKL 619
           +GF+P  +S+PLY +D    +Y+ LT   Y  ++ G +++
Sbjct: 691 EGFDPSTLSDPLYVLDQAVGAYLPLTTARYSALLAGNLRI 730


>gi|13325057 solute carrier family 27 (fatty acid transporter),
           member 5 [Homo sapiens]
          Length = 690

 Score =  497 bits (1280), Expect = e-140
 Identities = 259/601 (43%), Positives = 385/601 (64%), Gaps = 11/601 (1%)

Query: 30  DFWFVLKVVLIIIRLKKYEKRGELVTVLDKFLSHAKRQPRKPFIIYEGD---IYTYQDVD 86
           D  F+ K++ + ++++    R    T +D F   A+ QP +  +++ G      T+ ++D
Sbjct: 90  DVIFLAKILHLGLKIRGCLSRQPPDTFVDAFERRARAQPGRALLVWTGPGAGSVTFGELD 149

Query: 87  KRSSRVAHVFL----NHSSLKKGDTVALLM--SNEPDFVHVWFGLAKLGCVVAFLNTNIR 140
            R+ + A        + +SL  G+  ALL+  S     + +W GLAKLGC  A++N + R
Sbjct: 150 ARACQAAWALKAELGDPASLCAGEPTALLVLASQAVPALCMWLGLAKLGCPTAWINPHGR 209

Query: 141 SNSLLNCIRACGPRALVVGADLLGTVEEILPSL-SENISVWGMKDSVPQ-GVISLKEKLS 198
              L + + + G R LVV  DL  ++EEILP L +ENI  + +  + P  GV +L   L 
Sbjct: 210 GMPLAHSVLSSGARVLVVDPDLRESLEEILPKLQAENIRCFYLSHTSPTPGVGALGAALD 269

Query: 199 TSPDEPVPRSHHVVSLLKSTCLYIFTSGTTGLPKAAVISQLQVLRGSAVLWAFGCTAHDI 258
            +P  PVP         +S  L+I+TSGTTGLPK A+++  +VL+ S +L   G TA D+
Sbjct: 270 AAPSHPVPADLRAGITWRSPALFIYTSGTTGLPKPAILTHERVLQMSKMLSLSGATADDV 329

Query: 259 VYITLPLYHSSAAILGISGCVELGATCVLKKKFSASQFWSDCKKYDVTVFQYIGELCRYL 318
           VY  LPLYH    ++GI GC++LGATCVL  KFS S FW DC+++ VTV  Y+GEL RYL
Sbjct: 330 VYTVLPLYHVMGLVVGILGCLDLGATCVLAPKFSTSCFWDDCRQHGVTVILYVGELLRYL 389

Query: 319 CKQSKREGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVCELYAATESSISFMNYTGRIG 378
           C   ++  ++ H VRLA+GNG+R+DVW  F  RFG I++ E+Y +TE ++  +NY GR G
Sbjct: 390 CNIPQQPEDRTHTVRLAMGNGLRADVWETFQQRFGPIRIWEVYGSTEGNMGLVNYVGRCG 449

Query: 379 AIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLLISRVNAKNPFFGYA 438
           A+G+ +   ++LS F+L+++D +  EP+R+ QG+CI V  GEPGLL+++V ++ PF GY 
Sbjct: 450 ALGKMSCLLRMLSPFELVQFDMEAAEPVRDNQGFCIPVGLGEPGLLLTKVVSQQPFVGYR 509

Query: 439 GPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTFRWKGENVATTEVAD 498
           GP + ++ KL+ +V + GDVY NTGD++  D++ FLYF DR GDTFRWKGENV+T EV  
Sbjct: 510 GPRELSERKLVRNVRQSGDVYYNTGDVLAMDREGFLYFRDRLGDTFRWKGENVSTHEVEG 569

Query: 499 VIGMLDFIQEANVYGVAISGYEGRAGMASIILKPNTSLDLEKVYEQVVTFLPAYACPRFL 558
           V+  +DF+Q+ NVYGV + G EG+ GMA++ L P  + D EK+Y+ V  +LPAYA P F+
Sbjct: 570 VLSQVDFLQQVNVYGVCVPGCEGKVGMAAVQLAPGQTFDGEKLYQHVRAWLPAYATPHFI 629

Query: 559 RIQEKMEATGTFKLLKHQLVEDGFNPLKISEPLYFMDNLKKSYVLLTRELYDQIMLGEIK 618
           RIQ+ ME T TFKL+K +LV +GFN   + +PL+ +DN  +S+  LT E+Y  +  G  +
Sbjct: 630 RIQDAMEVTSTFKLMKTRLVREGFNVGIVVDPLFVLDNRAQSFRPLTAEMYQAVCEGTWR 689

Query: 619 L 619
           L
Sbjct: 690 L 690


>gi|40807357 solute carrier family 27 (fatty acid transporter),
           member 4 [Homo sapiens]
          Length = 643

 Score =  422 bits (1084), Expect = e-118
 Identities = 249/618 (40%), Positives = 350/618 (56%), Gaps = 23/618 (3%)

Query: 22  LLFPYFWDDFWFVLKV-------------VLIIIRLKKYEKRGELVTVLDKFLSHAKRQP 68
           LLF Y     W  ++V             VL+ ++ K  +   E  TV   F S  +R P
Sbjct: 29  LLFLYLGSGGWRFIRVFIKTIRRDIFGGLVLLKVKAKVRQCLQERRTVPILFASTVRRHP 88

Query: 69  RKPFIIYEGDI--YTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLA 126
            K  +I+EG    +T++ +D+ SS VA+ FL    L  GD  A+ M N  +FV +W G+A
Sbjct: 89  DKTALIFEGTDTHWTFRQLDEYSSSVAN-FLQARGLASGDVAAIFMENRNEFVGLWLGMA 147

Query: 127 KLGCVVAFLNTNIRSNSLLNCIRACGPRALVVGADLLGTVEEILPSLSENISVWGMKDSV 186
           KLG   A +NTN+R ++LL+C+     RALV G+++   + E+  SL  ++S++      
Sbjct: 148 KLGVEAALINTNLRRDALLHCLTTSRARALVFGSEMASAICEVHASLDPSLSLFCSGSWE 207

Query: 187 PQGVISLKEKLSTS-PDEPVPRSHHVVSLLKSTCLYIFTSGTTGLPKAAVISQLQVLRGS 245
           P  V    E L     D P                YI+TSGTTGLPKAA++   +  R +
Sbjct: 208 PGAVPPSTEHLDPLLKDAPKHLPSCPDKGFTDKLFYIYTSGTTGLPKAAIVVHSRYYRMA 267

Query: 246 A-VLWAFGCTAHDIVYITLPLYHSSAAILGISGCVELGATCVLKKKFSASQFWSDCKKYD 304
           A V + F    +DIVY  LPLYHS+  I+GI  C+  G T V++KKFSAS+FW DC KY+
Sbjct: 268 ALVYYGFRMRPNDIVYDCLPLYHSAGNIVGIGQCLLHGMTVVIRKKFSASRFWDDCIKYN 327

Query: 305 VTVFQYIGELCRYLCKQSKREGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVCELYAAT 364
            T+ QYIGELCRYL  Q  RE E  H+VR+A+GNG+R  +W  F  RF   +V E Y AT
Sbjct: 328 CTIVQYIGELCRYLLNQPPREAENQHQVRMALGNGLRQSIWTNFSSRFHIPQVAEFYGAT 387

Query: 365 ESSISFMNYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLL 424
           E + S  N+  ++GA G  +     +    L++ +    E +R   G CI  + GEPG L
Sbjct: 388 ECNCSLGNFDSQVGACGFNSRILSFVYPIRLVRVNEDTMELIRGPDGVCIPCQPGEPGQL 447

Query: 425 ISRVNAKNP---FFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTG 481
           + R+  K+P   F GY     + K K+  DVFKKGD    TGD++V D+  +LYF DRTG
Sbjct: 448 VGRIIQKDPLRRFDGYLNQGANNK-KIAKDVFKKGDQAYLTGDVLVMDELGYLYFRDRTG 506

Query: 482 DTFRWKGENVATTEVADVIGMLDFIQEANVYGVAISGYEGRAGMASIILKPNTSLDLEKV 541
           DTFRWKGENV+TTEV   +  L  + +  VYGV + G EGRAGMA+ +  P  + DLE+ 
Sbjct: 507 DTFRWKGENVSTTEVEGTLSRLLDMADVAVYGVEVPGTEGRAGMAA-VASPTGNCDLERF 565

Query: 542 YEQVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQLVEDGFNPLKISEPLYFMDNLKKSY 601
            + +   LP YA P FLR+  ++  TGT+K  K +L ++GF+P  + +PL+++D  K  Y
Sbjct: 566 AQVLEKELPLYARPIFLRLLPELHKTGTYKFQKTELRKEGFDPAIVKDPLFYLDAQKGRY 625

Query: 602 VLLTRELYDQIMLGEIKL 619
           V L +E Y +I  GE KL
Sbjct: 626 VPLDQEAYSRIQAGEEKL 643


>gi|38524616 solute carrier family 27, member 1 [Homo sapiens]
          Length = 646

 Score =  410 bits (1053), Expect = e-114
 Identities = 227/603 (37%), Positives = 354/603 (58%), Gaps = 23/603 (3%)

Query: 30  DFWFVLKVVLIIIRLKKYEKRGELVTVLDKFLSHAKRQPRKPFIIYEG--DIYTYQDVDK 87
           D + +  ++ + + L+++++ G  +  +  F +  +RQP +  ++  G  + +T+  +D 
Sbjct: 54  DLFGLSVLIRVRLELRRHQRAGHTIPRI--FQAVVQRQPERLALVDAGTGECWTFAQLDA 111

Query: 88  RSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLAKLGCVVAFLNTNIRSNSLLNC 147
            S+ VA++F        GD VA+ +   P+FV +W GLAK G   A LN N+R   L  C
Sbjct: 112 YSNAVANLF-RQLGFAPGDVVAIFLEGRPEFVGLWLGLAKAGMEAALLNVNLRREPLAFC 170

Query: 148 IRACGPRALVVGADLLGTVEEILPSLSENISVWGMKDSVPQGVIS-------LKEKLSTS 200
           +   G +AL+ G +++  V E+   L +++  +   D  P+G++        L ++ ST+
Sbjct: 171 LGTSGAKALIFGGEMVAAVAEVSGHLGKSLIKFCSGDLGPEGILPDTHLLDPLLKEASTA 230

Query: 201 PDEPVPRSHHVVSLLKSTCLYIFTSGTTGLPKAAVISQLQVLRGSAV-LWAFGCTAHDIV 259
           P   +P        +     YI+TSGTTGLPKAA++   +  R +A    A+   A D++
Sbjct: 231 PLAQIPSKG-----MDDRLFYIYTSGTTGLPKAAIVVHSRYYRMAAFGHHAYRMQAADVL 285

Query: 260 YITLPLYHSSAAILGISGCVELGATCVLKKKFSASQFWSDCKKYDVTVFQYIGELCRYLC 319
           Y  LPLYHS+  I+G+  C+  G T VL+KKFSAS+FW DC KY+ TV QYIGE+CRYL 
Sbjct: 286 YDCLPLYHSAGNIIGVGQCLIYGLTVVLRKKFSASRFWDDCIKYNCTVVQYIGEICRYLL 345

Query: 320 KQSKREGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVCELYAATESSISFMNYTGRIGA 379
           KQ  RE E+ H+VRLA+GNG+R  +W EF +RFG  ++ E Y ATE + S  N  G++G+
Sbjct: 346 KQPVREAERRHRVRLAVGNGLRPAIWEEFTERFGVRQIGEFYGATECNCSIANMDGKVGS 405

Query: 380 IGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLLISRVNAKNP---FFG 436
            G  +     +    L+K +    E +R+ QG CI  + GEPGLL+ ++N ++P   F G
Sbjct: 406 CGFNSRILPHVYPIRLVKVNEDTMELLRDAQGLCIPCQAGEPGLLVGQINQQDPLRRFDG 465

Query: 437 YAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTFRWKGENVATTEV 496
           Y      T  K+   VF KGD    +GD++V D+  ++YF DR+GDTFRW+GENV+TTEV
Sbjct: 466 YVSE-SATSKKIAHSVFSKGDSAYLSGDVLVMDELGYMYFRDRSGDTFRWRGENVSTTEV 524

Query: 497 ADVIGMLDFIQEANVYGVAISGYEGRAGMASIILKPNTSLDLEKVYEQVVTFLPAYACPR 556
             V+  L    +  VYGVA+ G EG+AGMA+ +  P++ LD   +Y+++   L  YA P 
Sbjct: 525 EGVLSRLLGQTDVAVYGVAVPGVEGKAGMAA-VADPHSLLDPNAIYQELQKVLAPYARPI 583

Query: 557 FLRIQEKMEATGTFKLLKHQLVEDGFNPLKISEPLYFMDNLKKSYVLLTRELYDQIMLGE 616
           FLR+  +++ TGTFK+ K +L  +GF+P + S+ L+F+D  +  Y+ L   +Y +I  G 
Sbjct: 584 FLRLLPQVDTTGTFKIQKTRLQREGFDPRQTSDRLFFLDLKQGHYLPLNEAVYTRICSGA 643

Query: 617 IKL 619
             L
Sbjct: 644 FAL 646


>gi|28416953 acyl-CoA synthetase short-chain family member 1 [Homo
           sapiens]
          Length = 689

 Score = 68.9 bits (167), Expect = 1e-11
 Identities = 116/566 (20%), Positives = 218/566 (38%), Gaps = 62/566 (10%)

Query: 51  GELVTVLDKFLSHAKRQPRKPFIIYEGDI------YTYQDVDKRSSRVAHVFLNHSSLKK 104
           G+L   ++    H ++ P    +I+E D        TY+++ + + R+A+    H  + +
Sbjct: 106 GQLNVSVNCLDQHVRKSPESVALIWERDEPGTEVRITYRELLETTCRLANTLKRHG-VHR 164

Query: 105 GDTVALLMSNEPDFVHVWFGLAKLGCVVAFLNTNIRSNSLLNCIRACGPRALVVG----- 159
           GD VA+ M   P  V      A++G V   +     + SL   I     + ++       
Sbjct: 165 GDRVAIYMPVSPLAVAAMLACARIGAVHTVIFAGFSAESLAGRINDAKCKVVITFNQGLR 224

Query: 160 ----ADLLGTVEEIL---PSLSENISVWGMKDSVPQGVISLKEKLSTSPDEPVPRSHHVV 212
                +L   V+E +   P++   +      + V  G + +  +   + ++PV     + 
Sbjct: 225 GGRVVELKKIVDEAVKHCPTVQHVLVAHRTDNKVHMGDLDVPLEQEMAKEDPVCAPESMG 284

Query: 213 SLLKSTCLYIFTSGTTGLPKAAVISQLQVLRGSAVLW----------AFGCTAHDIVYIT 262
           S  +     ++TSG+TG+PK  V +Q   L  +A+             FGC A DI +IT
Sbjct: 285 S--EDMLFMLYTSGSTGMPKGIVHTQAGYLLYAALTHKLVFDHQPGDIFGCVA-DIGWIT 341

Query: 263 LPLYHSSAAILGISGCVELGATCVLKKKF----SASQFWSDCKKYDVTVFQYIGELCRYL 318
              Y        + G +  GAT VL +      +A ++W   ++  +  F       R L
Sbjct: 342 GHSY-------VVYGPLCNGATSVLFESTPVYPNAGRYWETVERLKINQFYGAPTAVRLL 394

Query: 319 CKQS----KREGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVCELYAATESSISFMNYT 374
            K      K+      +   ++G  I  + W E+L R      C L         +   T
Sbjct: 395 LKYGDAWVKKYDRSSLRTLGSVGEPINCEAW-EWLHRVVGDSRCTLV-----DTWWQTET 448

Query: 375 GRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLLISRVNAKNPF 434
           G I    R +     +     ++  F     + +E+G  +        L IS+      +
Sbjct: 449 GGICIAPRPSEEGAEILPAMAMRPFFGIVPVLMDEKGSVVEGSNVSGALCISQA-----W 503

Query: 435 FGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTFRWKGENVATT 494
            G A        + +   FK    Y  TGD   + +  +     R  D     G  + T 
Sbjct: 504 PGMARTIYGDHQRFVDAYFKAYPGYYFTGDGAYRTEGGYYQITGRMDDVINISGHRLGTA 563

Query: 495 EVADVIGMLDFIQEANVYGVAISGYEGRAGMASIILKP---NTSLDLEKVYEQVVTFLPA 551
           E+ D I     + E+ V G      +G A  A I++K    ++ + ++++   V T +  
Sbjct: 564 EIEDAIADHPAVPESAVIGYP-HDIKGEAAFAFIVVKDSAGDSDVVVQELKSMVATKIAK 622

Query: 552 YACPRFLRIQEKMEATGTFKLLKHQL 577
           YA P  + + +++  T + K+++  L
Sbjct: 623 YAVPDEILVVKRLPKTRSGKVMRRLL 648


>gi|42544132 SA hypertension-associated homolog isoform 1 [Homo
           sapiens]
          Length = 586

 Score = 67.0 bits (162), Expect = 5e-11
 Identities = 108/514 (21%), Positives = 210/514 (40%), Gaps = 46/514 (8%)

Query: 80  YTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLAKLGCVVAFLNTNI 139
           ++++++   S + A++     SL++GD V L++   P++        + G V+    T +
Sbjct: 95  WSFEELGSLSRKFANILSEACSLQRGDRVILILPRVPEWWLANVACLRTGTVLIPGTTQL 154

Query: 140 RSNSLLNCIRACGPRALVVGADLLGTVEEILPSLSENI-SVWGMKDSVPQGVISLKEKLS 198
               +L  +++     ++   D+L    + + S  EN+ S   + ++  +G  +LKE + 
Sbjct: 155 TQKDILYRLQSSKANCIITN-DVLAPAVDAVASKCENLHSKLIVSENSREGWGNLKELMK 213

Query: 199 TSPDEPVPRSHHVVSLLKSTCLYIF-TSGTTGLPKAAVISQLQVLRGSAVLWAF--GCTA 255
            + D     SH  V    +  + IF TSGT+G PK    +      G +V   F    T 
Sbjct: 214 HASD-----SHTCVKTKHNEIMAIFFTSGTSGYPKMTAHTHSSFGLGLSVNGRFWLDLTP 268

Query: 256 HDIVYITLPLYHSSAAILGISGCVELGATCVLKK---KFSASQFWSDCKKYDVTVFQYIG 312
            D+++ T     + +A   +      GA CV      +F  +       KY +TVF    
Sbjct: 269 SDVMWNTSDTGWAKSAWSSVFSPWIQGA-CVFTHHLPRFEPTSILQTLSKYPITVFCSAP 327

Query: 313 ELCRYLCKQSKREGE-KDHKVRLAIGNGIRSDVWREFLDRFGNIKVCELYAATESSISFM 371
            + R L +      + K  K  ++ G  I  DV  ++ ++ G + + E Y  TE+ +   
Sbjct: 328 TVYRMLVQNDITSYKFKSLKHCVSAGEPITPDVTEKWRNKTG-LDIYEGYGQTETVLICG 386

Query: 372 NYTG---RIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLLISRV 428
           N+ G   + G++G+ +        FD+   D   +            +  G+ G +  +V
Sbjct: 387 NFKGMKIKPGSMGKPS------PAFDVKIVDVNGNV-----------LPPGQEGDIGIQV 429

Query: 429 NAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTFRWKG 488
               PF G    Y     K    +  +G+ Y+ TGD    D+D + +F  R  D     G
Sbjct: 430 LPNRPF-GLFTHYVDNPSKTASTL--RGNFYI-TGDRGYMDKDGYFWFVARADDVILSSG 485

Query: 489 ENVATTEVADVIGMLDFIQEANVYGVAISGYEGRAGMASIILKPNTSLD-----LEKVYE 543
             +   EV + +     + E+ V   +     G    A ++L P+         ++++ E
Sbjct: 486 YRIGPFEVENALNEHPSVAESAVVS-SPDPIRGEVVKAFVVLNPDYKSHDQEQLIKEIQE 544

Query: 544 QVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQL 577
            V      Y  PR +   +++  T + K  +++L
Sbjct: 545 HVKKTTAPYKYPRKVEFIQELPKTISGKTKRNEL 578


>gi|122937307 acyl-CoA synthetase medium-chain family member 4 [Homo
           sapiens]
          Length = 580

 Score = 64.3 bits (155), Expect = 3e-10
 Identities = 114/518 (22%), Positives = 203/518 (39%), Gaps = 54/518 (10%)

Query: 80  YTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLAKLGCVVAFLNTNI 139
           ++++++   S + A+V      L++GD +A+++   P++  V     + G +       +
Sbjct: 89  WSFRELGSLSRKAANVLTKPCGLQRGDRLAVILPRIPEWWLVNVACIRTGIIFMPGTIQL 148

Query: 140 RSNSLLNCIRACGPRALVVGADLLGTVEEIL---PSLSENISVWGMKDSVPQ---GVISL 193
            +  +L  +RA   + +V   ++   VE I+   P L   + V       PQ   G +S 
Sbjct: 149 TAKDILYRLRASKAKCIVASEEVAPAVESIVLECPDLKTKLLV------SPQSWNGWLSF 202

Query: 194 KEKLSTSPDEPVPRSHHVVSLLKSTCLYI-FTSGTTGLPKAAVISQLQVLRGSAVLWAF- 251
           +E    + +E     H  V       + I FTSGTTG PK A  SQ  +  G  +   + 
Sbjct: 203 QELFQFASEE-----HSCVETGSQEPMTIYFTSGTTGFPKMAQHSQSSLGIGFTLCGRYW 257

Query: 252 -GCTAHDIVYITLPLYHSSAAILGISGCVELGATCVLKK--KFSASQFWSDCKKYDVTVF 308
               + DI++         AAI  +      GA   + +  +F    F      Y +T  
Sbjct: 258 LDLKSSDIIWNMSDTGWVKAAIGSVFSSWLCGACVFVHRMAQFDTDTFLDTLTTYPITTL 317

Query: 309 QYIGELCRYLC-KQSKREGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVCELYAATESS 367
                + R L  K  KR   K  +  L  G  +  +V  ++  + G +++ E Y  TE  
Sbjct: 318 CSPPTVYRMLVQKDLKRYKFKSLRHCLTGGEPLNPEVLEQWRVQTG-LELYEGYGQTEVG 376

Query: 368 ISFMNYTG---RIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLL 424
           +   N  G   + G++G+            ++ YD Q  +   N       +  G+ G +
Sbjct: 377 MICANQKGQEIKPGSMGK-----------GMLPYDVQIIDENGNV------LPPGKEGEI 419

Query: 425 ISRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTF 484
             R+    PF  +   Y     K    +  +GD Y+ TGD  V D D + +F  R  D  
Sbjct: 420 ALRLKPTRPFC-FFSKYVDNPQKTAATI--RGDFYV-TGDRGVMDSDGYFWFVGRADDVI 475

Query: 485 RWKGENVATTEVADVIGMLDFIQEANVYGVAISGYEGRAGMASIIL-KPNTSLDLEK--- 540
              G  +   EV   +     + E+ V   +     G    A ++L  P  S + EK   
Sbjct: 476 ISSGYRIGPFEVESALIEHPAVVESAVVS-SPDQIRGEVVKAFVVLAAPFKSYNPEKLTL 534

Query: 541 -VYEQVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQL 577
            + + V      Y  PR +   +++  T T K+ ++ L
Sbjct: 535 ELQDHVKKSTAPYKYPRKVEFVQELPKTITGKIKRNVL 572


>gi|157311624 acyl-CoA synthetase medium-chain family member 2B
           [Homo sapiens]
          Length = 577

 Score = 63.9 bits (154), Expect = 4e-10
 Identities = 110/516 (21%), Positives = 207/516 (40%), Gaps = 49/516 (9%)

Query: 79  IYTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLAKLGCVVAFLNTN 138
           ++ ++++ + S + A++      L++GD VA+++   P++  V  G  + G +       
Sbjct: 80  MWNFRELSENSQQAANILSGACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMPGTIQ 139

Query: 139 IRSNSLLNCIRACGPRALVVGADLLGTVEEIL---PSLSENISVWGMKDSVPQGVISLKE 195
           ++S  +L  ++    +A+V G +++  V+ +    PSL   + V    +    G ++ K+
Sbjct: 140 MKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIKLLV---SEKSCDGWLNFKK 196

Query: 196 KLSTSPDEPVPRSHHVVSL--LKSTCLYIFTSGTTGLPKAAVISQLQV-LRGSAVLWAFG 252
            L+ +       +HH V     +++ +Y FTSGT+GLPK A  S   + L+        G
Sbjct: 197 LLNEAST-----THHCVETGSQEASAIY-FTSGTSGLPKMAEHSYSSLGLKAKMDAGWTG 250

Query: 253 CTAHDIVYITLPLYHSSAAILGISGCV----ELGATCV--LKKKFSASQFWSDCKKYDVT 306
             A DI++        +  IL I G +     LGA     L  KF           Y + 
Sbjct: 251 LQASDIMW----TISDTGWILNILGSLLESWTLGACTFVHLLPKFDPLVILKTLSSYPIK 306

Query: 307 VFQYIGELCRYLCKQSKREGEKDHKVR-LAIGNGIRSDVWREFLDRFGNIKVCELYAATE 365
                  + R L +Q     +  H    LA G  +  +    +  + G + + E Y  TE
Sbjct: 307 SMMGAPIVYRMLLQQDLSSYKFPHLQNCLAGGESLLPETLENWRAQTG-LDIREFYGQTE 365

Query: 366 SSISFMNYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLLI 425
           + ++ M        + +T              YD Q  +   N       +  G  G + 
Sbjct: 366 TGLTCM--------VSKTMKIKPGYMGTAASCYDVQVIDDKGNV------LPPGTEGDIG 411

Query: 426 SRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTFR 485
            RV    P   ++G Y    DK   ++  +GD +L  GD  ++D+D +  F  R  D   
Sbjct: 412 IRVKPIRPIGIFSG-YVENPDKTAANI--RGDFWL-LGDRGIKDEDGYFQFMGRADDIIN 467

Query: 486 WKGENVATTEVADVIGMLDFIQEANVYGV--AISGYEGRAG--MASIILKPNTSLDLEKV 541
             G  +  +EV + +     + E  V      + G   +A   +AS  L  +     +++
Sbjct: 468 SSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVILASQFLSHDPEQLTKEL 527

Query: 542 YEQVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQL 577
            + V +    Y  PR +     +  T T K+ + +L
Sbjct: 528 QQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRTKL 563


>gi|157311622 acyl-CoA synthetase medium-chain family member 2B
           [Homo sapiens]
          Length = 577

 Score = 63.9 bits (154), Expect = 4e-10
 Identities = 110/516 (21%), Positives = 207/516 (40%), Gaps = 49/516 (9%)

Query: 79  IYTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLAKLGCVVAFLNTN 138
           ++ ++++ + S + A++      L++GD VA+++   P++  V  G  + G +       
Sbjct: 80  MWNFRELSENSQQAANILSGACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMPGTIQ 139

Query: 139 IRSNSLLNCIRACGPRALVVGADLLGTVEEIL---PSLSENISVWGMKDSVPQGVISLKE 195
           ++S  +L  ++    +A+V G +++  V+ +    PSL   + V    +    G ++ K+
Sbjct: 140 MKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIKLLV---SEKSCDGWLNFKK 196

Query: 196 KLSTSPDEPVPRSHHVVSL--LKSTCLYIFTSGTTGLPKAAVISQLQV-LRGSAVLWAFG 252
            L+ +       +HH V     +++ +Y FTSGT+GLPK A  S   + L+        G
Sbjct: 197 LLNEAST-----THHCVETGSQEASAIY-FTSGTSGLPKMAEHSYSSLGLKAKMDAGWTG 250

Query: 253 CTAHDIVYITLPLYHSSAAILGISGCV----ELGATCV--LKKKFSASQFWSDCKKYDVT 306
             A DI++        +  IL I G +     LGA     L  KF           Y + 
Sbjct: 251 LQASDIMW----TISDTGWILNILGSLLESWTLGACTFVHLLPKFDPLVILKTLSSYPIK 306

Query: 307 VFQYIGELCRYLCKQSKREGEKDHKVR-LAIGNGIRSDVWREFLDRFGNIKVCELYAATE 365
                  + R L +Q     +  H    LA G  +  +    +  + G + + E Y  TE
Sbjct: 307 SMMGAPIVYRMLLQQDLSSYKFPHLQNCLAGGESLLPETLENWRAQTG-LDIREFYGQTE 365

Query: 366 SSISFMNYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLLI 425
           + ++ M        + +T              YD Q  +   N       +  G  G + 
Sbjct: 366 TGLTCM--------VSKTMKIKPGYMGTAASCYDVQVIDDKGNV------LPPGTEGDIG 411

Query: 426 SRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTFR 485
            RV    P   ++G Y    DK   ++  +GD +L  GD  ++D+D +  F  R  D   
Sbjct: 412 IRVKPIRPIGIFSG-YVENPDKTAANI--RGDFWL-LGDRGIKDEDGYFQFMGRADDIIN 467

Query: 486 WKGENVATTEVADVIGMLDFIQEANVYGV--AISGYEGRAG--MASIILKPNTSLDLEKV 541
             G  +  +EV + +     + E  V      + G   +A   +AS  L  +     +++
Sbjct: 468 SSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVILASQFLSHDPEQLTKEL 527

Query: 542 YEQVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQL 577
            + V +    Y  PR +     +  T T K+ + +L
Sbjct: 528 QQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRTKL 563


>gi|38505220 acyl-CoA synthetase medium-chain family member 5 [Homo
           sapiens]
          Length = 579

 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 114/517 (22%), Positives = 202/517 (39%), Gaps = 53/517 (10%)

Query: 80  YTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLAKLGCVVAFLNTNI 139
           ++++++ K+S + A+V      L+ GD + L++   P++  V     + G V+    T +
Sbjct: 90  WSFEELGKQSRKAANVLGGACGLQPGDRMMLVLPRLPEWWLVSVACMRTGTVMIPGVTQL 149

Query: 140 RSNSLLNCIRACGPRALVVGADLLGTVEEI---LPSLSENISVWGMKDSVPQGVISLKEK 196
               L   ++A   ++++    L   V+ I    PSL   + V    DS   G ++ +E 
Sbjct: 150 TEKDLKYRLQASRAKSIITSDSLAPRVDAISAECPSLQTKLLV---SDSSRPGWLNFREL 206

Query: 197 LSTSPDEPVPRSHHVVSLLKSTCLYI-FTSGTTGLPKAAVISQLQVLRG---SAVLWAFG 252
           L  +  E     H+ +       L I FTSGTTG PK    SQ     G   S   W   
Sbjct: 207 LREASTE-----HNCMRTKSRDPLAIYFTSGTTGAPKMVEHSQSSYGLGFVASGRRWV-A 260

Query: 253 CTAHDIVYITLPLYHSSAAILGISGCVELGATCVL---KKKFSASQFWSDCKKYDVTVFQ 309
            T  DI + T       AA    S       +C+      +  A    +   K+ +T   
Sbjct: 261 LTESDIFWNTTDTGWVKAAWTLFSAWP--NGSCIFVHELPRVDAKVILNTLSKFPITTLC 318

Query: 310 YIGELCRYLCKQS-KREGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVCELYAATESSI 368
            +  + R L ++   R   +  +  L  G  +  DV  ++  + G +++ E Y  +E+ +
Sbjct: 319 CVPTIFRLLVQEDLTRYQFQSLRHCLTGGEALNPDVREKWKHQTG-VELYEGYGQSETVV 377

Query: 369 SFMNYTG---RIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLLI 425
              N  G   + G++G+ +             YD Q  +   N       +  GE G + 
Sbjct: 378 ICANPKGMKIKSGSMGKAS-----------PPYDVQIVDDEGNV------LPPGEEGNVA 420

Query: 426 SRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTFR 485
            R+    PF  +   Y    +K      ++GD Y+ TGD    D+D + +F  R  D   
Sbjct: 421 VRIRPTRPFC-FFNCYLDNPEKTAAS--EQGDFYI-TGDRARMDKDGYFWFMGRNDDVIN 476

Query: 486 WKGENVATTEVADVIGMLDFIQEANVYGVAISGYEGRAGMASIILKP-NTSLDLE----K 540
                +   EV   +     + E+ V   +     G    A I+L P  +S D E    +
Sbjct: 477 SSSYRIGPVEVESALAEHPAVLESAVVS-SPDPIRGEVVKAFIVLTPAYSSHDPEALTRE 535

Query: 541 VYEQVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQL 577
           + E V      Y  PR +    ++  T + K+ + +L
Sbjct: 536 LQEHVKRVTAPYKYPRKVAFVSELPKTVSGKIQRSKL 572


>gi|115511026 acyl-CoA synthetase medium-chain family member 1 [Homo
           sapiens]
          Length = 577

 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 120/557 (21%), Positives = 213/557 (38%), Gaps = 77/557 (13%)

Query: 56  VLDKFLSHAKRQPRKP-----FIIYEGDI--YTYQDVDKRSSRVAHVFLNHSSLKKGDTV 108
           VLD +    K   R P     ++  +GD   ++++++   + RVA+VF     L++GD +
Sbjct: 55  VLDYWAQKEKEGKRGPNPAFWWVNGQGDEVKWSFREMGDLTRRVANVFTQTCGLQQGDHL 114

Query: 109 ALLMSNEPDFVHVWFGLAKLGCVVAFLNTNIRSNSLLNCIRACGPRALVVGADLLGTVEE 168
           AL++   P++  V  G  + G +       +++  +L  ++    + +V    L   V+ 
Sbjct: 115 ALMLPRVPEWWLVAVGCMRTGIIFIPATILLKAKDILYRLQLSKAKGIVTIDALASEVDS 174

Query: 169 I---LPSLSENISVWGMKDSVPQGVISLKEKL-STSPDEPVPRSHHVVSLLKSTCLYIFT 224
           I    PSL   + V    D   +G +  +  + S SP+    +S  +        +  FT
Sbjct: 175 IASQCPSLKTKLLV---SDHSREGWLDFRSLVKSASPEHTCVKSKTL-----DPMVIFFT 226

Query: 225 SGTTGLPKAAVIS-------------QLQVLRGSAVLWAFGCTAHDIVYITLPLYHSSAA 271
           SGTTG PK A  S             +L+ L+ S V W    +   +  I   +   +A 
Sbjct: 227 SGTTGFPKMAKHSHGLALQPSFPGSRKLRSLKTSDVSWCLSDSGWIVATIWTLVEPWTA- 285

Query: 272 ILGISGCVELGATCVLK--KKFSASQFWSDCKKYDVTVFQYIGELCRYLCKQSKREGEKD 329
                     G T  +    +F          KY +  F  +  + R + +Q        
Sbjct: 286 ----------GCTVFIHHLPQFDTKVIIQTLLKYPINHFWGVSSIYRMILQQDFTSIRFP 335

Query: 330 HKVRLAIGNGIRSDVWREFLDRFGNIKVCELYAATESSISFMNYTG---RIGAIGRTNLF 386
                  G  +     +E   R   + + E Y  +E+ +    Y G   + G +G+    
Sbjct: 336 ALEHCYTGGEVVLPKDQEEWKRRTGLLLYENYGQSETGLICATYWGMKIKPGFMGKATPP 395

Query: 387 YKLLSTFDLIKYDFQKDEPMRNEQGWCIHVK-KGEPGLLISRVNAKNPFFGYAGPYKHTK 445
           Y               D  + +++G  +    +G  G+ I  V   + F  Y G  + T 
Sbjct: 396 Y---------------DVQVIDDKGSILPPNTEGNIGIRIKPVRPVSLFMCYEGDPEKTA 440

Query: 446 DKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTFRWKGENVATTEVADVIGMLDF 505
            K+ C     GD Y NTGD    D++ ++ F  R+ D     G  +   EV   +     
Sbjct: 441 -KVEC-----GDFY-NTGDRGKMDEEGYICFLGRSDDIINASGYRIGPAEVESALVEHPA 493

Query: 506 IQEANVYGVAISGYEGRAGMASIILKP----NTSLDLEKVYEQVVTFLPA-YACPRFLRI 560
           + E+ V G +     G    A I+L P    +    L K  +Q V  + A Y  PR +  
Sbjct: 494 VAESAVVG-SPDPIRGEVVKAFIVLTPQFLSHDKDQLTKELQQHVKSVTAPYKYPRKVEF 552

Query: 561 QEKMEATGTFKLLKHQL 577
             ++  T T K+ + +L
Sbjct: 553 VSELPKTITGKIERKEL 569


>gi|239756507 PREDICTED: similar to Acyl-coenzyme A synthetase
           ACSM2B, mitochondrial isoform 2 [Homo sapiens]
          Length = 571

 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 108/517 (20%), Positives = 207/517 (40%), Gaps = 57/517 (11%)

Query: 79  IYTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLAKLGCVVAFLNTN 138
           ++ ++++ + S + A+V      L++GD VA+++   P++  V  G  + G +       
Sbjct: 80  MWNFRELSENSQQAANVLSGACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMPGTIQ 139

Query: 139 IRSNSLLNCIRACGPRALVVGADLLGTVEEIL---PSLSENISVWGMKDSVPQGVISLKE 195
           ++S  +L  ++    +A+V G +++  V+ +    PSL   + V    +    G ++ K+
Sbjct: 140 MKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIKLLV---SEKSCDGWLNFKK 196

Query: 196 KLSTSPDEPVPRSHHVVSL--LKSTCLYIFTSGTTGLPKAAVISQLQV-LRGSAVLWAFG 252
            L+ +       +HH V     +++ +Y FTSGT+GLPK A  S   + L+        G
Sbjct: 197 LLNEAST-----THHCVETGSQEASAIY-FTSGTSGLPKMAEHSYSSLGLKAKMDAGWTG 250

Query: 253 CTAHDIVYITLPLYHSSAAILGISGCV----ELGATCV--LKKKFSASQFWSDCKKYDVT 306
             A DI++        +  IL I G +     LGA     L  KF           Y + 
Sbjct: 251 LQASDIMW----TISDTGWILNILGSLLESWTLGACTFVHLLPKFDPLVILKTLSSYPIK 306

Query: 307 VFQYIGELCRYLCKQSKREGEKDHKVR-LAIGNGIRSDVWREFLDRFGNIKVCELYAATE 365
                  + R L +Q     +  H    LA G  +  +    +  + G + + E Y  TE
Sbjct: 307 SMMGAPIVYRMLLQQDLSSYKFPHLQNCLAGGESLLPETLENWRAQTG-LDIREFYGQTE 365

Query: 366 SSISFM-NYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLL 424
           + ++ M + T +I    +        S +D+    F    P   + G+            
Sbjct: 366 TGLTCMVSKTMKI----KPGYMGTAASCYDVQVIAFVHGSPRAGDLGF------------ 409

Query: 425 ISRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTF 484
                A      + G ++   DK   ++  +GD +L  GD  ++D+D +  F  R  D  
Sbjct: 410 -----AGTMTLSFCG-HQENPDKTAANI--RGDFWL-LGDRGIKDEDGYFQFMGRADDII 460

Query: 485 RWKGENVATTEVADVIGMLDFIQEANVYGV--AISGYEGRAG--MASIILKPNTSLDLEK 540
              G  +  +EV + +     + E  V      + G   +A   +AS  L  +     ++
Sbjct: 461 NSSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVILASQFLSHDPEQLTKE 520

Query: 541 VYEQVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQL 577
           + + V +    Y  PR +     +  T T K+ + +L
Sbjct: 521 LQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRTKL 557


>gi|239756505 PREDICTED: similar to Acyl-coenzyme A synthetase
           ACSM2B, mitochondrial isoform 1 [Homo sapiens]
          Length = 571

 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 108/517 (20%), Positives = 207/517 (40%), Gaps = 57/517 (11%)

Query: 79  IYTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLAKLGCVVAFLNTN 138
           ++ ++++ + S + A+V      L++GD VA+++   P++  V  G  + G +       
Sbjct: 80  MWNFRELSENSQQAANVLSGACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMPGTIQ 139

Query: 139 IRSNSLLNCIRACGPRALVVGADLLGTVEEIL---PSLSENISVWGMKDSVPQGVISLKE 195
           ++S  +L  ++    +A+V G +++  V+ +    PSL   + V    +    G ++ K+
Sbjct: 140 MKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIKLLV---SEKSCDGWLNFKK 196

Query: 196 KLSTSPDEPVPRSHHVVSL--LKSTCLYIFTSGTTGLPKAAVISQLQV-LRGSAVLWAFG 252
            L+ +       +HH V     +++ +Y FTSGT+GLPK A  S   + L+        G
Sbjct: 197 LLNEAST-----THHCVETGSQEASAIY-FTSGTSGLPKMAEHSYSSLGLKAKMDAGWTG 250

Query: 253 CTAHDIVYITLPLYHSSAAILGISGCV----ELGATCV--LKKKFSASQFWSDCKKYDVT 306
             A DI++        +  IL I G +     LGA     L  KF           Y + 
Sbjct: 251 LQASDIMW----TISDTGWILNILGSLLESWTLGACTFVHLLPKFDPLVILKTLSSYPIK 306

Query: 307 VFQYIGELCRYLCKQSKREGEKDHKVR-LAIGNGIRSDVWREFLDRFGNIKVCELYAATE 365
                  + R L +Q     +  H    LA G  +  +    +  + G + + E Y  TE
Sbjct: 307 SMMGAPIVYRMLLQQDLSSYKFPHLQNCLAGGESLLPETLENWRAQTG-LDIREFYGQTE 365

Query: 366 SSISFM-NYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLL 424
           + ++ M + T +I    +        S +D+    F    P   + G+            
Sbjct: 366 TGLTCMVSKTMKI----KPGYMGTAASCYDVQVIAFVHGSPRAGDLGF------------ 409

Query: 425 ISRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTF 484
                A      + G ++   DK   ++  +GD +L  GD  ++D+D +  F  R  D  
Sbjct: 410 -----AGTMTLSFCG-HQENPDKTAANI--RGDFWL-LGDRGIKDEDGYFQFMGRADDII 460

Query: 485 RWKGENVATTEVADVIGMLDFIQEANVYGV--AISGYEGRAG--MASIILKPNTSLDLEK 540
              G  +  +EV + +     + E  V      + G   +A   +AS  L  +     ++
Sbjct: 461 NSSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVILASQFLSHDPEQLTKE 520

Query: 541 VYEQVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQL 577
           + + V +    Y  PR +     +  T T K+ + +L
Sbjct: 521 LQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRTKL 557


>gi|58082049 acyl-CoA synthetase medium-chain family member 2A [Homo
           sapiens]
          Length = 577

 Score = 60.1 bits (144), Expect = 6e-09
 Identities = 90/431 (20%), Positives = 173/431 (40%), Gaps = 37/431 (8%)

Query: 79  IYTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLAKLGCVVAFLNTN 138
           ++ ++++ + S + A+V      L++GD VA+++   P++  V  G  + G +       
Sbjct: 80  MWNFRELSENSQQAANVLSGACGLQRGDRVAVVLPRVPEWWLVILGCIRAGLIFMPGTIQ 139

Query: 139 IRSNSLLNCIRACGPRALVVGADLLGTVEEIL---PSLSENISVWGMKDSVPQGVISLKE 195
           ++S  +L  ++    +A+V G +++  V+ +    PSL   + V    +    G ++ K+
Sbjct: 140 MKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIKLLV---SEKSCDGWLNFKK 196

Query: 196 KLSTSPDEPVPRSHHVVSL--LKSTCLYIFTSGTTGLPKAAVISQLQV-LRGSAVLWAFG 252
            L+ +       +HH V     +++ +Y FTSGT+GLPK A  S   + L+        G
Sbjct: 197 LLNEAST-----THHCVETGSQEASAIY-FTSGTSGLPKMAEHSYSSLGLKAKMDAGWTG 250

Query: 253 CTAHDIVYITLPLYHSSAAILGISGCVELGATCV--LKKKFSASQFWSDCKKYDVTVFQY 310
             A DI++           +  +     LGA     L  KF           Y +     
Sbjct: 251 LQASDIMWTISDTGWILNILCSLMEPWALGACTFVHLLPKFDPLVILKTLSSYPIKSMMG 310

Query: 311 IGELCRYLCKQSKREGEKDHKVR-LAIGNGIRSDVWREFLDRFGNIKVCELYAATESSIS 369
              + R L +Q     +  H    + +G  +  +    +  + G + + E Y  TE+ ++
Sbjct: 311 APIVYRMLLQQDLSSYKFPHLQNCVTVGESLLPETLENWRAQTG-LDIRESYGQTETGLT 369

Query: 370 FMNYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLLISRVN 429
            M        + +T              YD Q  +   N       +  G  G +  RV 
Sbjct: 370 CM--------VSKTMKIKPGYMGTAASCYDVQIIDDKGNV------LPPGTEGDIGIRVK 415

Query: 430 AKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTFRWKGE 489
              P   ++G Y    DK   ++  +GD +L  GD  ++D+D +  F  R  D     G 
Sbjct: 416 PIRPIGIFSG-YVDNPDKTAANI--RGDFWL-LGDRGIKDEDGYFQFMGRADDIINSSGY 471

Query: 490 NVATTEVADVI 500
            +  +EV + +
Sbjct: 472 RIGPSEVENAL 482


>gi|187761345 acyl-CoA synthetase family member 3 [Homo sapiens]
          Length = 576

 Score = 59.7 bits (143), Expect = 8e-09
 Identities = 89/399 (22%), Positives = 153/399 (38%), Gaps = 55/399 (13%)

Query: 220 LYIFTSGTTGLPKAAVISQLQ---VLRGSAVLWAFGCTAHDIVYITLPLYHSSAAILGIS 276
           + I+TSGTTG PK  + +      V+ G    WA+  T  D++   LPL+H    +  + 
Sbjct: 198 MIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKWAW--TKDDVILHVLPLHHVHGVVNALL 255

Query: 277 GCVELGATCVLKKKFSASQFWSDCKKYD---VTVFQYIGELCRYLCKQSKREGEKDH--- 330
             + +GATCV+  +FS  Q W      +   + VF  +  +   L +   R   + H   
Sbjct: 256 CPLWVGATCVMMPEFSPQQVWEKFLSSETPRINVFMAVPTIYTKLMEYYDRHFTQPHAQD 315

Query: 331 --------KVRLAIGNGIRSDVWREFLDRFGNI---KVCELYAATESSISF---MNYTGR 376
                   K+RL +       +    L+++ NI    + E Y  TE  ++    +    R
Sbjct: 316 FLRAVCEEKIRLMVSGSAALPL--PVLEKWKNITGHTLLERYGMTEIGMALSGPLTTAVR 373

Query: 377 I-GAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLLIS--------- 426
           + G++G         +    ++     + P R    + IH +  E G  ++         
Sbjct: 374 LPGSVG---------TPLPGVQVRIVSENPQREACSYTIHAEGDERGTKVTPGFEEKEGE 424

Query: 427 -RVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTFR 485
             V   + F  Y    + TK     D + K      TGD +V     +      + D  +
Sbjct: 425 LLVRGPSVFREYWNKPEETKSAFTLDGWFK------TGDTVVFKDGQYWIRGRTSVDIIK 478

Query: 486 WKGENVATTEVADVIGMLDFIQEANVYGVAISGYEGRAGMASIILKPNTSLDLEKVYEQV 545
             G  V+  EV   +     I +  V GV    + G+   A + L+   SL   ++ E  
Sbjct: 479 TGGYKVSALEVEWHLLAHPSITDVAVIGVPDMTW-GQRVTAVVTLREGHSLSHRELKEWA 537

Query: 546 VTFLPAYACPRFLRIQEKMEATGTFKLLKHQLVEDGFNP 584
              L  YA P  L + E++      K+ K  L+   F+P
Sbjct: 538 RNVLAPYAVPSELVLVEEIPRNQMGKIDKKALIRH-FHP 575


>gi|187761343 acyl-CoA synthetase family member 3 [Homo sapiens]
          Length = 576

 Score = 59.7 bits (143), Expect = 8e-09
 Identities = 89/399 (22%), Positives = 153/399 (38%), Gaps = 55/399 (13%)

Query: 220 LYIFTSGTTGLPKAAVISQLQ---VLRGSAVLWAFGCTAHDIVYITLPLYHSSAAILGIS 276
           + I+TSGTTG PK  + +      V+ G    WA+  T  D++   LPL+H    +  + 
Sbjct: 198 MIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKWAW--TKDDVILHVLPLHHVHGVVNALL 255

Query: 277 GCVELGATCVLKKKFSASQFWSDCKKYD---VTVFQYIGELCRYLCKQSKREGEKDH--- 330
             + +GATCV+  +FS  Q W      +   + VF  +  +   L +   R   + H   
Sbjct: 256 CPLWVGATCVMMPEFSPQQVWEKFLSSETPRINVFMAVPTIYTKLMEYYDRHFTQPHAQD 315

Query: 331 --------KVRLAIGNGIRSDVWREFLDRFGNI---KVCELYAATESSISF---MNYTGR 376
                   K+RL +       +    L+++ NI    + E Y  TE  ++    +    R
Sbjct: 316 FLRAVCEEKIRLMVSGSAALPL--PVLEKWKNITGHTLLERYGMTEIGMALSGPLTTAVR 373

Query: 377 I-GAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLLIS--------- 426
           + G++G         +    ++     + P R    + IH +  E G  ++         
Sbjct: 374 LPGSVG---------TPLPGVQVRIVSENPQREACSYTIHAEGDERGTKVTPGFEEKEGE 424

Query: 427 -RVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTFR 485
             V   + F  Y    + TK     D + K      TGD +V     +      + D  +
Sbjct: 425 LLVRGPSVFREYWNKPEETKSAFTLDGWFK------TGDTVVFKDGQYWIRGRTSVDIIK 478

Query: 486 WKGENVATTEVADVIGMLDFIQEANVYGVAISGYEGRAGMASIILKPNTSLDLEKVYEQV 545
             G  V+  EV   +     I +  V GV    + G+   A + L+   SL   ++ E  
Sbjct: 479 TGGYKVSALEVEWHLLAHPSITDVAVIGVPDMTW-GQRVTAVVTLREGHSLSHRELKEWA 537

Query: 546 VTFLPAYACPRFLRIQEKMEATGTFKLLKHQLVEDGFNP 584
              L  YA P  L + E++      K+ K  L+   F+P
Sbjct: 538 RNVLAPYAVPSELVLVEEIPRNQMGKIDKKALIRH-FHP 575


>gi|13375727 acyl-CoA synthetase short-chain family member 3 [Homo
           sapiens]
          Length = 686

 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 52/200 (26%), Positives = 93/200 (46%), Gaps = 27/200 (13%)

Query: 57  LDKFLSHAKRQPRKPFIIYEGDI------YTYQDVDKRSSRVAHVFLNHSSLKKGDTVAL 110
           +D+ + + K    K  IIY+  +      +TY++V ++ S++A V + H  +KKGDTV +
Sbjct: 117 VDRHIENGKGD--KIAIIYDSPVTNTKATFTYKEVLEQVSKLAGVLVKHG-IKKGDTVVI 173

Query: 111 LMSNEPDFVHVWFGLAKLGCVVAFLNTNIRSNSLLNCIRACGPRALVVGADLL--GTVEE 168
            M   P  ++     A++G + + +     S  L + I    P+ +V  +  +  G   E
Sbjct: 174 YMPMIPQAMYTMLACARIGAIHSLIFGGFASKELSSRIDHVKPKVVVTASFGIEPGRRVE 233

Query: 169 ILPSLSENISVWGMK------------DSVPQGVISLKEKLSTSPDEPVPRSHHVVSLLK 216
            +P + E + +   K            ++VP   ++    L    +    +SH  V +L 
Sbjct: 234 YVPLVEEALKIGQHKPDKILIYNRPNMEAVP---LAPGRDLDWDEEMAKAQSHDCVPVLS 290

Query: 217 STCLYI-FTSGTTGLPKAAV 235
              LYI +TSGTTGLPK  +
Sbjct: 291 EHPLYILYTSGTTGLPKGVI 310



 Score = 33.1 bits (74), Expect = 0.78
 Identities = 23/98 (23%), Positives = 42/98 (42%), Gaps = 9/98 (9%)

Query: 453 FKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTFRWKGENVATTEVADVIGMLDFIQEANVY 512
           F+K   Y +T D    D++ +LY   R  D     G  ++   + + I     +    V 
Sbjct: 528 FEKFPGYYDTMDAGYMDEEGYLYVMSRVDDVINVAGHRISAGAIEESI-----LSHGTVA 582

Query: 513 GVAISGYE----GRAGMASIILKPNTSLDLEKVYEQVV 546
             A+ G E    G   +A  +L+ + +   E+V E++V
Sbjct: 583 DCAVVGKEDPLKGHVPLALCVLRKDINATEEQVLEEIV 620


>gi|42544134 SA hypertension-associated homolog isoform 2 [Homo
           sapiens]
          Length = 438

 Score = 53.5 bits (127), Expect = 6e-07
 Identities = 70/314 (22%), Positives = 137/314 (43%), Gaps = 19/314 (6%)

Query: 80  YTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLAKLGCVVAFLNTNI 139
           ++++++   S + A++     SL++GD V L++   P++        + G V+    T +
Sbjct: 95  WSFEELGSLSRKFANILSEACSLQRGDRVILILPRVPEWWLANVACLRTGTVLIPGTTQL 154

Query: 140 RSNSLLNCIRACGPRALVVGADLLGTVEEILPSLSENI-SVWGMKDSVPQGVISLKEKLS 198
               +L  +++     ++   D+L    + + S  EN+ S   + ++  +G  +LKE + 
Sbjct: 155 TQKDILYRLQSSKANCIITN-DVLAPAVDAVASKCENLHSKLIVSENSREGWGNLKELMK 213

Query: 199 TSPDEPVPRSHHVVSLLKSTCLYIF-TSGTTGLPKAAVISQLQVLRGSAVLWAF--GCTA 255
            + D     SH  V    +  + IF TSGT+G PK    +      G +V   F    T 
Sbjct: 214 HASD-----SHTCVKTKHNEIMAIFFTSGTSGYPKMTAHTHSSFGLGLSVNGRFWLDLTP 268

Query: 256 HDIVYITLPLYHSSAAILGISGCVELGATCVLK---KKFSASQFWSDCKKYDVTVFQYIG 312
            D+++ T     + +A   +      GA CV      +F  +       KY +TVF    
Sbjct: 269 SDVMWNTSDTGWAKSAWSSVFSPWIQGA-CVFTHHLPRFEPTSILQTLSKYPITVFCSAP 327

Query: 313 ELCRYLCKQSKREGE-KDHKVRLAIGNGIRSDVWREFLDRFGNIKVCELYAATESSISFM 371
            + R L +      + K  K  ++ G  I  DV  ++ ++ G + + E Y  TE+ +   
Sbjct: 328 TVYRMLVQNDITSYKFKSLKHCVSAGEPITPDVTEKWRNKTG-LDIYEGYGQTETVLICG 386

Query: 372 NYTG---RIGAIGR 382
           N+ G   + G++G+
Sbjct: 387 NFKGMKIKPGSMGK 400


>gi|8923896 acyl-CoA synthetase short-chain family member 2 isoform
           1 [Homo sapiens]
          Length = 701

 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 111/517 (21%), Positives = 184/517 (35%), Gaps = 81/517 (15%)

Query: 56  VLDKFLSHAKRQPRKPFIIYEGDI------YTYQDVDKRSSRVAHVFLNHSSLKKGDTVA 109
           VLD+ + H K+   K    +EG+        TY  +  +  + ++V L    ++KGD VA
Sbjct: 107 VLDRNV-HEKKLGDKVAFYWEGNEPGETTQITYHQLLVQVCQFSNV-LRKQGIQKGDRVA 164

Query: 110 LLMSNEPDFVHVWFGLAKLGCVVAFLNTNIRSNSLLNCI--RACGPRALVVGADLLGTVE 167
           + M   P+ V      A++G + + +     S SL   I   +C   +L++  D     E
Sbjct: 165 IYMPMIPELVVAMLACARIGALHSIVFAGFSSESLCERILDSSC---SLLITTDAFYRGE 221

Query: 168 EI--LPSLSENISVWGMKDSVPQGVISLKEKL---------STSPDEPVPRS-------- 208
           ++  L  L++       +   P     + + L         STS   P+ RS        
Sbjct: 222 KLVNLKELADEALQKCQEKGFPVRCCIVVKHLGRAELGMGDSTSQSPPIKRSCPDVQISW 281

Query: 209 --------HHVVSLLKSTC-----------LYIFTSGTTGLPKAAV--ISQLQVLRGSAV 247
                   H ++      C             ++TSG+TG PK  V  +    +   +  
Sbjct: 282 NQGIDLWWHELMQEAGDECEPEWCDAEDPLFILYTSGSTGKPKGVVHTVGGYMLYVATTF 341

Query: 248 LWAFGCTAHDIVYITLPLYHSSAAILGISGCVELGATCVLKKKF----SASQFWSDCKKY 303
            + F   A D+ + T  +   +       G +  GAT VL +        ++ WS   KY
Sbjct: 342 KYVFDFHAEDVFWCTADIGWITGHSYVTYGPLANGATSVLFEGIPTYPDVNRLWSIVDKY 401

Query: 304 DVTVFQYIGELCRYLCKQSKREGEKDHKVRL----AIGNGIRSDVWREFLDRFG--NIKV 357
            VT F       R L K       K  +  L     +G  I  + W  +    G     +
Sbjct: 402 KVTKFYTAPTAIRLLMKFGDEPVTKHSRASLQVLGTVGEPINPEAWLWYHRVVGAQRCPI 461

Query: 358 CELYAATESSISFMNYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVK 417
            + +  TE+    +        +          +TF      F     + NE G      
Sbjct: 462 VDTFWQTETGGHMLT------PLPGATPMKPGSATFPF----FGVAPAILNESG---EEL 508

Query: 418 KGE-PGLLISRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYF 476
           +GE  G L+     K P+ G         ++     FKK   Y  TGD   +DQD + + 
Sbjct: 509 EGEAEGYLV----FKQPWPGIMRTVYGNHERFETTYFKKFPGYYVTGDGCQRDQDGYYWI 564

Query: 477 WDRTGDTFRWKGENVATTEVADVIGMLDFIQEANVYG 513
             R  D     G  ++T EV   +   + + EA V G
Sbjct: 565 TGRIDDMLNVSGHLLSTAEVESALVEHEAVAEAAVVG 601


>gi|253970489 acyl-CoA synthetase short-chain family member 2
           isoform 2 [Homo sapiens]
          Length = 714

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 111/530 (20%), Positives = 184/530 (34%), Gaps = 94/530 (17%)

Query: 56  VLDKFLSHAKRQPRKPFIIYEGDI------YTYQDVDKRSSRVAHVFLNHSSLKKGDTVA 109
           VLD+ + H K+   K    +EG+        TY  +  +  + ++V L    ++KGD VA
Sbjct: 107 VLDRNV-HEKKLGDKVAFYWEGNEPGETTQITYHQLLVQVCQFSNV-LRKQGIQKGDRVA 164

Query: 110 LLMSNEPDFVHVWFGLAKLGCVVAFLNTNIRSNSLLNCI--RACGPRALVVGADLLGTVE 167
           + M   P+ V      A++G + + +     S SL   I   +C   +L++  D     E
Sbjct: 165 IYMPMIPELVVAMLACARIGALHSIVFAGFSSESLCERILDSSC---SLLITTDAFYRGE 221

Query: 168 EI--LPSLSENISVWGMKDSVPQGVISLKEKL---------STSPDEPVPRS-------- 208
           ++  L  L++       +   P     + + L         STS   P+ RS        
Sbjct: 222 KLVNLKELADEALQKCQEKGFPVRCCIVVKHLGRAELGMGDSTSQSPPIKRSCPDVQGKL 281

Query: 209 ---------------------HHVVSLLKSTC-----------LYIFTSGTTGLPKAAV- 235
                                H ++      C             ++TSG+TG PK  V 
Sbjct: 282 KEKSKRVQPQISWNQGIDLWWHELMQEAGDECEPEWCDAEDPLFILYTSGSTGKPKGVVH 341

Query: 236 -ISQLQVLRGSAVLWAFGCTAHDIVYITLPLYHSSAAILGISGCVELGATCVLKKKF--- 291
            +    +   +   + F   A D+ + T  +   +       G +  GAT VL +     
Sbjct: 342 TVGGYMLYVATTFKYVFDFHAEDVFWCTADIGWITGHSYVTYGPLANGATSVLFEGIPTY 401

Query: 292 -SASQFWSDCKKYDVTVFQYIGELCRYLCKQSKREGEKDHKVRL----AIGNGIRSDVWR 346
              ++ WS   KY VT F       R L K       K  +  L     +G  I  + W 
Sbjct: 402 PDVNRLWSIVDKYKVTKFYTAPTAIRLLMKFGDEPVTKHSRASLQVLGTVGEPINPEAWL 461

Query: 347 EFLDRFG--NIKVCELYAATESSISFMNYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDE 404
            +    G     + + +  TE+    +        +          +TF      F    
Sbjct: 462 WYHRVVGAQRCPIVDTFWQTETGGHMLT------PLPGATPMKPGSATFPF----FGVAP 511

Query: 405 PMRNEQGWCIHVKKGE-PGLLISRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTG 463
            + NE G      +GE  G L+     K P+ G         ++     FKK   Y  TG
Sbjct: 512 AILNESG---EELEGEAEGYLV----FKQPWPGIMRTVYGNHERFETTYFKKFPGYYVTG 564

Query: 464 DLIVQDQDNFLYFWDRTGDTFRWKGENVATTEVADVIGMLDFIQEANVYG 513
           D   +DQD + +   R  D     G  ++T EV   +   + + EA V G
Sbjct: 565 DGCQRDQDGYYWITGRIDDMLNVSGHLLSTAEVESALVEHEAVAEAAVVG 614


>gi|156151445 acyl-CoA synthetase family member 2 [Homo sapiens]
          Length = 615

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 53/232 (22%), Positives = 95/232 (40%), Gaps = 34/232 (14%)

Query: 83  QDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLAKLGCVVAFLNTNIRSN 142
           ++VDK +S +  +      L KGD + +   N   +V +    A+ G ++  +N   ++ 
Sbjct: 107 EEVDKAASGLLSI-----GLCKGDRLGMWGPNSYAWVLMQLATAQAGIILVSVNPAYQAM 161

Query: 143 SLLNCIRACGPRALVVGADL-----LGTVEEILPSLSENISVWGMK-------------D 184
            L   ++  G +ALV             +++I P + EN     +K             D
Sbjct: 162 ELEYVLKKVGCKALVFPKQFKTQQYYNVLKQICPEV-ENAQPGALKSQRLPDLTTVISVD 220

Query: 185 SVPQGVISLKEKLST-SPDEPVPRSHHVVSLLK--STCLYIFTSGTTGLPKAAVISQLQV 241
           +   G + L E ++  S  + + +  +    L         FTSGTTG PK A +S   +
Sbjct: 221 APLPGTLLLDEVVAAGSTRQHLDQLQYNQQFLSCHDPINIQFTSGTTGSPKGATLSHYNI 280

Query: 242 LRGSAVLWAFGCTAHD------IVYITLPLYHSSAAILGISGCVELGATCVL 287
           +  S +L       H+       + +  PLYH   ++ G   C+  GAT +L
Sbjct: 281 VNNSNIL-GERLKLHEKTPEQLRMILPNPLYHCLGSVAGTMMCLMYGATLIL 331



 Score = 32.0 bits (71), Expect = 1.7
 Identities = 29/123 (23%), Positives = 48/123 (39%), Gaps = 1/123 (0%)

Query: 457 DVYLNTGDLIVQDQDNFLYFWDRTGDTFRWKGENVATTEVADVIGMLDFIQEANVYGVAI 516
           D +  TGD+   ++  F     R+ D     GEN+   E+ D       +QE  V GV  
Sbjct: 486 DKWYWTGDVATMNEQGFCKIVGRSKDMIIRGGENIYPAELEDFFHTHPKVQEVQVVGVK- 544

Query: 517 SGYEGRAGMASIILKPNTSLDLEKVYEQVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQ 576
               G    A I LK      +E++       +  +  P+++        T + K+ K +
Sbjct: 545 DDRMGEEICACIRLKDGEETTVEEIKAFCKGKISHFKIPKYIVFVTNYPLTISGKIQKFK 604

Query: 577 LVE 579
           L E
Sbjct: 605 LRE 607


>gi|195947378 acyl-coenzyme A synthetase ACSM6, mitochondrial [Homo
           sapiens]
          Length = 480

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 81/428 (18%), Positives = 160/428 (37%), Gaps = 41/428 (9%)

Query: 76  EGDIYTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLAKLGCVVAFL 135
           E D ++++ + + S + A +  +  +L  GD + +++   P+   +     +LG      
Sbjct: 82  EEDKWSFERMTQLSKKAASILSDTCALSHGDRLMIILPPTPEAYWICLACVRLGITFVPG 141

Query: 136 NTNIRSNSLLNCIRACGPRALVVG---ADLLGTVEEILPSLSENISVWGMKDSVPQGVIS 192
           +  + +  +   +R    + +V     A ++ +     P+L   + V    D    G + 
Sbjct: 142 SPQLTAKKIRYQLRMSKAQCIVANEAMAPVVNSAVSDCPTLKTKLLV---SDKSYDGWLD 198

Query: 193 LKEKLSTSPDEPVPRSHHVVSLLKSTCLYIFTSGTTGLPKAAVISQLQVLRG---SAVLW 249
            K+ +  +P    P+  ++ +  +      FT GTTG PK    SQ  +  G   ++  W
Sbjct: 199 FKKLIQVAP----PKQTYMRTKSQDPMAIFFTKGTTGAPKMVEYSQYGLGMGFSQASRRW 254

Query: 250 AFGCTAHDIVYITLPLYHSSAAILGISGCVELGATCVL--KKKFSASQFWSDCKKYDVTV 307
                  D+++     +  S ++  + G    GA   L     F      +   ++ +T 
Sbjct: 255 -MDLQPTDVLWSLGDAFGGSLSLSAVLGTWFQGACVFLCHMPTFCPETVLNVLSRFPITT 313

Query: 308 F----QYIGELCRYLCKQSKREGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVCELYAA 363
                +   EL ++ C  S R   K  K  +A G  I   V  ++  R   + + E Y  
Sbjct: 314 LSANPEMYQELLQHKCFTSYR--FKSLKQCVAAGGPISPGVIEDW-KRITKLDIYEGYGQ 370

Query: 364 TESSISFMNYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGL 423
           TE        TG + A  +T           L  Y  Q  +   N       +  GE G 
Sbjct: 371 TE--------TGLLCATSKTIKLKPSSLGKPLPPYIVQIVDENSN------LLPPGEEGN 416

Query: 424 LISRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDT 483
           +  R+    P   Y  P+  + ++       +G +   TGD  + D+D + ++  R  D 
Sbjct: 417 IAIRIKLNQPASLYC-PHMVSWEEY---ASARGHMLYLTGDRGIMDEDGYFWWSGRVDDV 472

Query: 484 FRWKGENV 491
               G+ +
Sbjct: 473 ANALGQRL 480


>gi|27477105 lipidosin [Homo sapiens]
          Length = 724

 Score = 40.0 bits (92), Expect = 0.006
 Identities = 51/210 (24%), Positives = 84/210 (40%), Gaps = 24/210 (11%)

Query: 91  RVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLAKLGCVVAFLNTNIRSNSLLNCIRA 150
           R A  FL    LK+  +VA+L  N P++     G    G +V  + T     +       
Sbjct: 144 RAAKGFLK-LGLKQAHSVAILGFNSPEWFFSAVGTVFAGGIVTGIYTTSSPEACQYIAYD 202

Query: 151 CGPRALVVGADL-LGTVEEILPSLSENISVWGMKDSVPQ---GVISLKEKLSTSPDEPVP 206
           C    ++V     L  + +I   L    +V   K+  P     V +++E +    + P  
Sbjct: 203 CCANVIMVDTQKQLEKILKIWKQLPHLKAVVIYKEPPPNKMANVYTMEEFMELGNEVPEE 262

Query: 207 RSHHVVSLLKST--CLYIFTSGTTGLPKAAVISQLQVLRGSAVLWA--FGCTAHDI---- 258
               ++   +    C+ ++TSGTTG PK  ++SQ        + W   +G  A DI    
Sbjct: 263 ALDAIIDTQQPNQCCVLVYTSGTTGNPKGVMLSQ------DNITWTARYGSQAGDIRPAE 316

Query: 259 -----VYITLPLYHSSAAILGISGCVELGA 283
                V   LPL H +A I  +   ++ GA
Sbjct: 317 VQQEVVVSYLPLSHIAAQIYDLWTGIQWGA 346



 Score = 29.6 bits (65), Expect = 8.6
 Identities = 31/115 (26%), Positives = 52/115 (45%), Gaps = 15/115 (13%)

Query: 441 YKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGD-TFRWKGENVATTEVADV 499
           Y + +DK    + ++G  +L+TGD    D D FLY   R  +      GENV    + + 
Sbjct: 529 YLNMEDKTCEAIDEEG--WLHTGDAGRLDADGFLYITGRLKELIITAGGENVPPVPIEEA 586

Query: 500 IGM-LDFIQEANVYGVAISGYEGRAGMASII-----LKPNTSLDLEKVYEQVVTF 548
           + M L  I  A + G      + R  ++ ++     L P+TS   + + EQ + F
Sbjct: 587 VKMELPIISNAMLIG------DQRKFLSMLLTLKCTLDPDTSDQTDNLTEQAMEF 635


>gi|42794760 acyl-CoA synthetase long-chain family member 5 isoform
           b [Homo sapiens]
          Length = 683

 Score = 37.4 bits (85), Expect = 0.041
 Identities = 50/224 (22%), Positives = 90/224 (40%), Gaps = 33/224 (14%)

Query: 66  RQPRKPFIIYEGDIYTYQDVDKRSSRVAHVFLNHSSLKKGDT-VALLMSNEPDFVHVWFG 124
           R+P +P+        +Y+ V  R+  +    L+       D  V +   N P+++     
Sbjct: 97  RKPNQPY-----RWLSYKQVSDRAEYLGSCLLHKGYKSSPDQFVGIFAQNRPEWIISELA 151

Query: 125 LAKLGCVVAFLNTNIRSNSLLNCIRACGPRALVVGAD-----LLGTVEE-ILPSLSENIS 178
                 V   L   +   ++++ +       ++         L+G VE+   PSL   I 
Sbjct: 152 CYTYSMVAVPLYDTLGPEAIVHIVNKADIAMVICDTPQKALVLIGNVEKGFTPSLKVIIL 211

Query: 179 VWGMKDSVPQG-------VISLKEKLSTSPD---EPVPRSHHVVSLLKSTCLYIFTSGTT 228
           +    D + Q        ++SL +  +   +   +PVP S   +S++       FTSGTT
Sbjct: 212 MDPFDDDLKQRGEKSGIEILSLYDAENLGKEHFRKPVPPSPEDLSVI------CFTSGTT 265

Query: 229 GLPKAAVISQLQVLRGSA-----VLWAFGCTAHDIVYITLPLYH 267
           G PK A+I+   ++  +A     V  A+  T  D+    LPL H
Sbjct: 266 GDPKGAMITHQNIVSNAAAFLKCVEHAYEPTPDDVAISYLPLAH 309


>gi|42794758 acyl-CoA synthetase long-chain family member 5 isoform
           b [Homo sapiens]
          Length = 683

 Score = 37.4 bits (85), Expect = 0.041
 Identities = 50/224 (22%), Positives = 90/224 (40%), Gaps = 33/224 (14%)

Query: 66  RQPRKPFIIYEGDIYTYQDVDKRSSRVAHVFLNHSSLKKGDT-VALLMSNEPDFVHVWFG 124
           R+P +P+        +Y+ V  R+  +    L+       D  V +   N P+++     
Sbjct: 97  RKPNQPY-----RWLSYKQVSDRAEYLGSCLLHKGYKSSPDQFVGIFAQNRPEWIISELA 151

Query: 125 LAKLGCVVAFLNTNIRSNSLLNCIRACGPRALVVGAD-----LLGTVEE-ILPSLSENIS 178
                 V   L   +   ++++ +       ++         L+G VE+   PSL   I 
Sbjct: 152 CYTYSMVAVPLYDTLGPEAIVHIVNKADIAMVICDTPQKALVLIGNVEKGFTPSLKVIIL 211

Query: 179 VWGMKDSVPQG-------VISLKEKLSTSPD---EPVPRSHHVVSLLKSTCLYIFTSGTT 228
           +    D + Q        ++SL +  +   +   +PVP S   +S++       FTSGTT
Sbjct: 212 MDPFDDDLKQRGEKSGIEILSLYDAENLGKEHFRKPVPPSPEDLSVI------CFTSGTT 265

Query: 229 GLPKAAVISQLQVLRGSA-----VLWAFGCTAHDIVYITLPLYH 267
           G PK A+I+   ++  +A     V  A+  T  D+    LPL H
Sbjct: 266 GDPKGAMITHQNIVSNAAAFLKCVEHAYEPTPDDVAISYLPLAH 309


>gi|42794756 acyl-CoA synthetase long-chain family member 5 isoform
           a [Homo sapiens]
          Length = 739

 Score = 37.4 bits (85), Expect = 0.041
 Identities = 50/224 (22%), Positives = 90/224 (40%), Gaps = 33/224 (14%)

Query: 66  RQPRKPFIIYEGDIYTYQDVDKRSSRVAHVFLNHSSLKKGDT-VALLMSNEPDFVHVWFG 124
           R+P +P+        +Y+ V  R+  +    L+       D  V +   N P+++     
Sbjct: 153 RKPNQPY-----RWLSYKQVSDRAEYLGSCLLHKGYKSSPDQFVGIFAQNRPEWIISELA 207

Query: 125 LAKLGCVVAFLNTNIRSNSLLNCIRACGPRALVVGAD-----LLGTVEE-ILPSLSENIS 178
                 V   L   +   ++++ +       ++         L+G VE+   PSL   I 
Sbjct: 208 CYTYSMVAVPLYDTLGPEAIVHIVNKADIAMVICDTPQKALVLIGNVEKGFTPSLKVIIL 267

Query: 179 VWGMKDSVPQG-------VISLKEKLSTSPD---EPVPRSHHVVSLLKSTCLYIFTSGTT 228
           +    D + Q        ++SL +  +   +   +PVP S   +S++       FTSGTT
Sbjct: 268 MDPFDDDLKQRGEKSGIEILSLYDAENLGKEHFRKPVPPSPEDLSVI------CFTSGTT 321

Query: 229 GLPKAAVISQLQVLRGSA-----VLWAFGCTAHDIVYITLPLYH 267
           G PK A+I+   ++  +A     V  A+  T  D+    LPL H
Sbjct: 322 GDPKGAMITHQNIVSNAAAFLKCVEHAYEPTPDDVAISYLPLAH 365


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.140    0.429 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,207,007
Number of Sequences: 37866
Number of extensions: 961339
Number of successful extensions: 2096
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 27
Number of HSP's that attempted gapping in prelim test: 2031
Number of HSP's gapped (non-prelim): 69
length of query: 619
length of database: 18,247,518
effective HSP length: 108
effective length of query: 511
effective length of database: 14,157,990
effective search space: 7234732890
effective search space used: 7234732890
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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