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Search of human proteins with 61743944
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|61743944 abl-interactor 1 isoform b [Homo sapiens]
(481 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|61743944 abl-interactor 1 isoform b [Homo sapiens] 988 0.0
gi|61743942 abl-interactor 1 isoform a [Homo sapiens] 973 0.0
gi|61743948 abl-interactor 1 isoform d [Homo sapiens] 971 0.0
gi|61743946 abl-interactor 1 isoform c [Homo sapiens] 905 0.0
gi|109689723 abl interactor 2 [Homo sapiens] 704 0.0
gi|7705981 NESH protein isoform 1 [Homo sapiens] 271 1e-72
gi|206597502 NESH protein isoform 2 [Homo sapiens] 261 8e-70
gi|194294523 intersectin 2 isoform 3 [Homo sapiens] 65 1e-10
gi|194294521 intersectin 2 isoform 1 [Homo sapiens] 65 1e-10
gi|194294525 intersectin 2 isoform 2 [Homo sapiens] 65 1e-10
gi|55741677 SET domain containing 1A [Homo sapiens] 63 7e-10
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] 62 9e-10
gi|46094081 development and differentiation enhancing factor 1 [... 62 2e-09
gi|116284392 mucin 2 precursor [Homo sapiens] 61 2e-09
gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens] 61 3e-09
gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens] 61 3e-09
gi|224586851 sorbin and SH3 domain containing 2 isoform 6 [Homo ... 60 4e-09
gi|224586846 sorbin and SH3 domain containing 2 isoform 4 [Homo ... 60 4e-09
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 60 4e-09
gi|51988887 SH3 domain containing ring finger 1 [Homo sapiens] 60 6e-09
gi|167234422 hematopoietic cell-specific Lyn substrate 1 [Homo s... 60 6e-09
gi|55956916 myosin IE [Homo sapiens] 59 7e-09
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 59 1e-08
gi|150417989 cyclin K isoform 1 [Homo sapiens] 59 1e-08
gi|224586855 sorbin and SH3 domain containing 2 isoform 8 [Homo ... 58 2e-08
gi|224586853 sorbin and SH3 domain containing 2 isoform 7 [Homo ... 58 2e-08
gi|224586849 sorbin and SH3 domain containing 2 isoform 5 [Homo ... 58 2e-08
gi|224586844 sorbin and SH3 domain containing 2 isoform 3 [Homo ... 58 2e-08
gi|203098098 shroom family member 3 protein [Homo sapiens] 58 2e-08
gi|10947118 sorbin and SH3 domain containing 2 isoform 2 [Homo s... 58 2e-08
>gi|61743944 abl-interactor 1 isoform b [Homo sapiens]
Length = 481
Score = 988 bits (2554), Expect = 0.0
Identities = 481/481 (100%), Positives = 481/481 (100%)
Query: 1 MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS 60
MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS
Sbjct: 1 MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS 60
Query: 61 VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR 120
VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR
Sbjct: 61 VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR 120
Query: 121 THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQK 180
THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQK
Sbjct: 121 THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQK 180
Query: 181 PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHS 240
PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHS
Sbjct: 181 PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHS 240
Query: 241 GSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPAAPGSAPGSQYGTMTRQISRHNSTTSS 300
GSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPAAPGSAPGSQYGTMTRQISRHNSTTSS
Sbjct: 241 GSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPAAPGSAPGSQYGTMTRQISRHNSTTSS 300
Query: 301 TSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQE 360
TSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQE
Sbjct: 301 TSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQE 360
Query: 361 NIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNY 420
NIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNY
Sbjct: 361 NIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNY 420
Query: 421 IEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESIMHYT 480
IEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESIMHYT
Sbjct: 421 IEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESIMHYT 480
Query: 481 D 481
D
Sbjct: 481 D 481
>gi|61743942 abl-interactor 1 isoform a [Homo sapiens]
Length = 508
Score = 973 bits (2516), Expect = 0.0
Identities = 481/508 (94%), Positives = 481/508 (94%), Gaps = 27/508 (5%)
Query: 1 MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS 60
MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS
Sbjct: 1 MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS 60
Query: 61 VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR 120
VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR
Sbjct: 61 VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR 120
Query: 121 THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQK 180
THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQK
Sbjct: 121 THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQK 180
Query: 181 PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHS 240
PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHS
Sbjct: 181 PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHS 240
Query: 241 GSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGP--------------------------- 273
GSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGP
Sbjct: 241 GSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENISVPPPSGAPPAPPLAPLLPVSTVI 300
Query: 274 AAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSI 333
AAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSI
Sbjct: 301 AAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSI 360
Query: 334 SIAPPPPPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVD 393
SIAPPPPPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVD
Sbjct: 361 SIAPPPPPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVD 420
Query: 394 YEDEEAAVVQYNDPYADGDPAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKND 453
YEDEEAAVVQYNDPYADGDPAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKND
Sbjct: 421 YEDEEAAVVQYNDPYADGDPAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKND 480
Query: 454 DGWYEGVCNRVTGLFPGNYVESIMHYTD 481
DGWYEGVCNRVTGLFPGNYVESIMHYTD
Sbjct: 481 DGWYEGVCNRVTGLFPGNYVESIMHYTD 508
>gi|61743948 abl-interactor 1 isoform d [Homo sapiens]
Length = 476
Score = 971 bits (2509), Expect = 0.0
Identities = 476/481 (98%), Positives = 476/481 (98%), Gaps = 5/481 (1%)
Query: 1 MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS 60
MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS
Sbjct: 1 MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS 60
Query: 61 VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR 120
VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR
Sbjct: 61 VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR 120
Query: 121 THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQK 180
THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVK HGNNQPARTGTLSRTNPPTQK
Sbjct: 121 THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVK-----HGNNQPARTGTLSRTNPPTQK 175
Query: 181 PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHS 240
PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHS
Sbjct: 176 PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHS 235
Query: 241 GSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPAAPGSAPGSQYGTMTRQISRHNSTTSS 300
GSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPAAPGSAPGSQYGTMTRQISRHNSTTSS
Sbjct: 236 GSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPAAPGSAPGSQYGTMTRQISRHNSTTSS 295
Query: 301 TSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQE 360
TSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQE
Sbjct: 296 TSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQE 355
Query: 361 NIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNY 420
NIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNY
Sbjct: 356 NIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNY 415
Query: 421 IEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESIMHYT 480
IEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESIMHYT
Sbjct: 416 IEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESIMHYT 475
Query: 481 D 481
D
Sbjct: 476 D 476
>gi|61743946 abl-interactor 1 isoform c [Homo sapiens]
Length = 452
Score = 905 bits (2339), Expect = 0.0
Identities = 448/481 (93%), Positives = 450/481 (93%), Gaps = 29/481 (6%)
Query: 1 MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS 60
MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS
Sbjct: 1 MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS 60
Query: 61 VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR 120
VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR
Sbjct: 61 VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR 120
Query: 121 THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQK 180
THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQK
Sbjct: 121 THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQK 180
Query: 181 PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHS 240
PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHS
Sbjct: 181 PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHS 240
Query: 241 GSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPAAPGSAPGSQYGTMTRQISRHNSTTSS 300
GSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPAAPGSAPGSQYGTMTRQISRHNSTTSS
Sbjct: 241 GSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPAAPGSAPGSQYGTMTRQISRHNSTTSS 300
Query: 301 TSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQE 360
TSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSI+ +P P
Sbjct: 301 TSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSIADSPTP--------------------- 339
Query: 361 NIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNY 420
PPPPPPDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNY
Sbjct: 340 --------PPPPPPDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNY 391
Query: 421 IEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESIMHYT 480
IEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESIMHYT
Sbjct: 392 IEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESIMHYT 451
Query: 481 D 481
D
Sbjct: 452 D 452
>gi|109689723 abl interactor 2 [Homo sapiens]
Length = 475
Score = 704 bits (1816), Expect = 0.0
Identities = 358/491 (72%), Positives = 406/491 (82%), Gaps = 26/491 (5%)
Query: 1 MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS 60
MAELQMLLEEEIP G+RAL +SY NL RVADYCENNYIQ+ DK++ALEETKAYTTQSLAS
Sbjct: 1 MAELQMLLEEEIPGGRRALFDSYTNLERVADYCENNYIQSADKQRALEETKAYTTQSLAS 60
Query: 61 VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR 120
VAY IN LANNVLQ+LDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR
Sbjct: 61 VAYLINTLANNVLQMLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR 120
Query: 121 THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQK 180
THKIIAPAN+ERPVRYIRKPIDYT+LDD+GHGVK + Q + G L RT PPTQK
Sbjct: 121 THKIIAPANLERPVRYIRKPIDYTILDDIGHGVK------VSTQNMKMGGLPRTTPPTQK 174
Query: 181 PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPAR--LGSQHSPGRTASLNQRPRT 238
PPSPPMSG+GTLGR++PY+TLEPV+PP VPNDY+ SP R SQ SP RTAS+NQR RT
Sbjct: 175 PPSPPMSGKGTLGRHSPYRTLEPVRPPVVPNDYVPSPTRNMAPSQQSPVRTASVNQRNRT 234
Query: 239 H--SGSSGG------SGSRENSGSSSIGIPIAVPTPSPPTIGPAAPGSAPGSQYGTMTRQ 290
+ SGSSGG S SRENSGS S+G+PIAVPTPSPP++ P P Q+ +M R
Sbjct: 235 YSSSGSSGGSHPSSRSSSRENSGSGSVGVPIAVPTPSPPSVFPGHP-----VQFYSMNRP 289
Query: 291 ISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQIP 350
SRH T S YRR PS+T+Q S Q +NGGP YSQN +S+APPPP + Q+TPQ+P
Sbjct: 290 ASRHTPPTIG-GSLPYRRPPSITSQTSLQNQMNGGPFYSQNPVSLAPPPPSILQVTPQLP 348
Query: 351 LTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYNDPYAD 410
L GFVARVQENI+D+ PPPPPP + P+FD+SPPPPPPP DYE+EEAAVV+Y+DPYA+
Sbjct: 349 LMGFVARVQENISDT---PPPPPPVEEPVFDESPPPPPPPE-DYEEEEAAVVEYSDPYAE 404
Query: 411 GDPAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPG 470
DP WAP++Y+EKVVAIYDYTKDK+DELSF EGAIIYVIKKNDDGWYEGV N VTGLFPG
Sbjct: 405 EDPPWAPRSYLEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPG 464
Query: 471 NYVESIMHYTD 481
NYVESIMHY++
Sbjct: 465 NYVESIMHYSE 475
>gi|7705981 NESH protein isoform 1 [Homo sapiens]
Length = 366
Score = 271 bits (692), Expect = 1e-72
Identities = 185/474 (39%), Positives = 244/474 (51%), Gaps = 111/474 (23%)
Query: 1 MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS 60
MAELQ L E EIP+G+ AL ++ L RVADYCE+NY+QATDKRKALEET A+TTQ+LAS
Sbjct: 1 MAELQQLQEFEIPTGREALRGNHSALLRVADYCEDNYVQATDKRKALEETMAFTTQALAS 60
Query: 61 VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR 120
VAYQ+ LA + L++LD+Q + LR++E+ ++ + Q V++H EKVARREIG L T +
Sbjct: 61 VAYQVGNLAGHTLRMLDLQGAALRQVEARVSTLGQMVNMHMEKVARREIGTLATVQRLPP 120
Query: 121 THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQK 180
K+IAP N+ Y R+P+++ LDD+GHG+K L + Q +RTGTLSR + K
Sbjct: 121 GQKVIAPENLPPLTPYCRRPLNFGCLDDIGHGIKDL-----STQLSRTGTLSR---KSIK 172
Query: 181 PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHS 240
P+ P S TLGR P + EPV P VP+ RL + S AS +
Sbjct: 173 APATPAS--ATLGR--PPRIPEPVHLPVVPD------GRLSAASSASSLAS--------A 214
Query: 241 GSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPAAPGSAPGSQYGTMTRQISRHNSTTSS 300
GS+ G G PTP G AAP + P
Sbjct: 215 GSAEGVG--------------GAPTPK----GQAAPPAPP-------------------L 237
Query: 301 TSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQE 360
SS P+ F P + ++PPPP ++PL
Sbjct: 238 PSSLDPPPPPAAVEVFQRPPTLE----------ELSPPPP-----DEELPL--------- 273
Query: 361 NIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNY 420
P PPPPP D D+ PPPPP + +P+W P +Y
Sbjct: 274 -----PLDLPPPPPLD---GDELGLPPPPP----------------GFGPDEPSWVPASY 309
Query: 421 IEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVE 474
+EKVV +Y YT KD+ELSF EG +I V ++ DGW EGV + TG FPGNYVE
Sbjct: 310 LEKVVTLYPYTSQKDNELSFSEGTVICVTRRYSDGWCEGVSSEGTGFFPGNYVE 363
>gi|206597502 NESH protein isoform 2 [Homo sapiens]
Length = 360
Score = 261 bits (668), Expect = 8e-70
Identities = 184/474 (38%), Positives = 241/474 (50%), Gaps = 117/474 (24%)
Query: 1 MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS 60
MAELQ L E EIP+G+ AL ++ L RVADYCE+NY+QATDKRKALEET A+TTQ+LAS
Sbjct: 1 MAELQQLQEFEIPTGREALRGNHSALLRVADYCEDNYVQATDKRKALEETMAFTTQALAS 60
Query: 61 VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR 120
VAYQ+ LA + L++LD+Q + LR++E ++ V++H EKVARREIG L T +
Sbjct: 61 VAYQVGNLAGHTLRMLDLQGAALRQVE------ARMVNMHMEKVARREIGTLATVQRLPP 114
Query: 121 THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQK 180
K+IAP N+ Y R+P+++ LDD+GHG+K L + Q +RTGTLSR + K
Sbjct: 115 GQKVIAPENLPPLTPYCRRPLNFGCLDDIGHGIKDL-----STQLSRTGTLSR---KSIK 166
Query: 181 PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHS 240
P+ P S TLGR P + EPV P VP+ RL + S AS +
Sbjct: 167 APATPAS--ATLGR--PPRIPEPVHLPVVPD------GRLSAASSASSLAS--------A 208
Query: 241 GSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPAAPGSAPGSQYGTMTRQISRHNSTTSS 300
GS+ G G PTP G AAP + P
Sbjct: 209 GSAEGVG--------------GAPTPK----GQAAPPAPP-------------------L 231
Query: 301 TSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQE 360
SS P+ F P + ++PPPP ++PL
Sbjct: 232 PSSLDPPPPPAAVEVFQRPPTLE----------ELSPPPP-----DEELPL--------- 267
Query: 361 NIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNY 420
P PPPPP D D+ PPPPP + +P+W P +Y
Sbjct: 268 -----PLDLPPPPPLD---GDELGLPPPPP----------------GFGPDEPSWVPASY 303
Query: 421 IEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVE 474
+EKVV +Y YT KD+ELSF EG +I V ++ DGW EGV + TG FPGNYVE
Sbjct: 304 LEKVVTLYPYTSQKDNELSFSEGTVICVTRRYSDGWCEGVSSEGTGFFPGNYVE 357
>gi|194294523 intersectin 2 isoform 3 [Homo sapiens]
Length = 1670
Score = 65.5 bits (158), Expect = 1e-10
Identities = 30/62 (48%), Positives = 44/62 (70%), Gaps = 3/62 (4%)
Query: 413 PAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNY 472
PA+ P + +V+A+YDY + +DELSF +G +I V+ K+D W++G N VTGLFP NY
Sbjct: 1097 PAFHP---VCQVIAMYDYAANNEDELSFSKGQLINVMNKDDPDWWQGEINGVTGLFPSNY 1153
Query: 473 VE 474
V+
Sbjct: 1154 VK 1155
Score = 43.1 bits (100), Expect = 6e-04
Identities = 28/87 (32%), Positives = 42/87 (48%), Gaps = 6/87 (6%)
Query: 388 PPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIY 447
P V E+ EA N P A + E+ +A+Y Y+ + +L+F EG I
Sbjct: 928 PGSEVKREEPEALYAAVNKK-----PTSAAYSVGEEYIALYPYSSVEPGDLTFTEGEEIL 982
Query: 448 VIKKNDDGWYEGVCNRVTGLFPGNYVE 474
V +K D W+ G +G+FP NYV+
Sbjct: 983 VTQK-DGEWWTGSIGDRSGIFPSNYVK 1008
Score = 36.6 bits (83), Expect = 0.052
Identities = 21/53 (39%), Positives = 27/53 (50%), Gaps = 2/53 (3%)
Query: 426 AIYDYTKDKDDELSFMEGAIIYVIKK--NDDGWYEGVCNRVTGLFPGNYVESI 476
A+Y + DE+SF G II V +K + GW G G FP NYVE +
Sbjct: 737 ALYPFEARNHDEMSFNSGDIIQVDEKTVGEPGWLYGSFQGNFGWFPCNYVEKM 789
Score = 35.0 bits (79), Expect = 0.15
Identities = 16/50 (32%), Positives = 26/50 (52%), Gaps = 5/50 (10%)
Query: 430 YTKDKDDELSFMEGAIIYVIKKNDDGWYEGVC-----NRVTGLFPGNYVE 474
Y ++LS G +I ++KKN GW++G R G FP ++V+
Sbjct: 1037 YVASGSEQLSLAPGQLILILKKNTSGWWQGELQARGKKRQKGWFPASHVK 1086
Score = 33.9 bits (76), Expect = 0.34
Identities = 18/54 (33%), Positives = 32/54 (59%), Gaps = 1/54 (1%)
Query: 423 KVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESI 476
K A+ +T KD+ L+F + II V+++ ++ W+ G + G FP +YV+ I
Sbjct: 875 KAQALCSWTAKKDNHLNFSKHDIITVLEQQENWWF-GEVHGGRGWFPKSYVKII 927
>gi|194294521 intersectin 2 isoform 1 [Homo sapiens]
Length = 1697
Score = 65.5 bits (158), Expect = 1e-10
Identities = 30/62 (48%), Positives = 44/62 (70%), Gaps = 3/62 (4%)
Query: 413 PAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNY 472
PA+ P + +V+A+YDY + +DELSF +G +I V+ K+D W++G N VTGLFP NY
Sbjct: 1124 PAFHP---VCQVIAMYDYAANNEDELSFSKGQLINVMNKDDPDWWQGEINGVTGLFPSNY 1180
Query: 473 VE 474
V+
Sbjct: 1181 VK 1182
Score = 43.1 bits (100), Expect = 6e-04
Identities = 28/87 (32%), Positives = 42/87 (48%), Gaps = 6/87 (6%)
Query: 388 PPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIY 447
P V E+ EA N P A + E+ +A+Y Y+ + +L+F EG I
Sbjct: 955 PGSEVKREEPEALYAAVNKK-----PTSAAYSVGEEYIALYPYSSVEPGDLTFTEGEEIL 1009
Query: 448 VIKKNDDGWYEGVCNRVTGLFPGNYVE 474
V +K D W+ G +G+FP NYV+
Sbjct: 1010 VTQK-DGEWWTGSIGDRSGIFPSNYVK 1035
Score = 36.6 bits (83), Expect = 0.052
Identities = 21/53 (39%), Positives = 27/53 (50%), Gaps = 2/53 (3%)
Query: 426 AIYDYTKDKDDELSFMEGAIIYVIKK--NDDGWYEGVCNRVTGLFPGNYVESI 476
A+Y + DE+SF G II V +K + GW G G FP NYVE +
Sbjct: 764 ALYPFEARNHDEMSFNSGDIIQVDEKTVGEPGWLYGSFQGNFGWFPCNYVEKM 816
Score = 35.0 bits (79), Expect = 0.15
Identities = 16/50 (32%), Positives = 26/50 (52%), Gaps = 5/50 (10%)
Query: 430 YTKDKDDELSFMEGAIIYVIKKNDDGWYEGVC-----NRVTGLFPGNYVE 474
Y ++LS G +I ++KKN GW++G R G FP ++V+
Sbjct: 1064 YVASGSEQLSLAPGQLILILKKNTSGWWQGELQARGKKRQKGWFPASHVK 1113
Score = 33.9 bits (76), Expect = 0.34
Identities = 18/54 (33%), Positives = 32/54 (59%), Gaps = 1/54 (1%)
Query: 423 KVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESI 476
K A+ +T KD+ L+F + II V+++ ++ W+ G + G FP +YV+ I
Sbjct: 902 KAQALCSWTAKKDNHLNFSKHDIITVLEQQENWWF-GEVHGGRGWFPKSYVKII 954
>gi|194294525 intersectin 2 isoform 2 [Homo sapiens]
Length = 1249
Score = 65.5 bits (158), Expect = 1e-10
Identities = 30/62 (48%), Positives = 44/62 (70%), Gaps = 3/62 (4%)
Query: 413 PAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNY 472
PA+ P + +V+A+YDY + +DELSF +G +I V+ K+D W++G N VTGLFP NY
Sbjct: 1124 PAFHP---VCQVIAMYDYAANNEDELSFSKGQLINVMNKDDPDWWQGEINGVTGLFPSNY 1180
Query: 473 VE 474
V+
Sbjct: 1181 VK 1182
Score = 43.1 bits (100), Expect = 6e-04
Identities = 28/87 (32%), Positives = 42/87 (48%), Gaps = 6/87 (6%)
Query: 388 PPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIY 447
P V E+ EA N P A + E+ +A+Y Y+ + +L+F EG I
Sbjct: 955 PGSEVKREEPEALYAAVNKK-----PTSAAYSVGEEYIALYPYSSVEPGDLTFTEGEEIL 1009
Query: 448 VIKKNDDGWYEGVCNRVTGLFPGNYVE 474
V +K D W+ G +G+FP NYV+
Sbjct: 1010 VTQK-DGEWWTGSIGDRSGIFPSNYVK 1035
Score = 36.6 bits (83), Expect = 0.052
Identities = 21/53 (39%), Positives = 27/53 (50%), Gaps = 2/53 (3%)
Query: 426 AIYDYTKDKDDELSFMEGAIIYVIKK--NDDGWYEGVCNRVTGLFPGNYVESI 476
A+Y + DE+SF G II V +K + GW G G FP NYVE +
Sbjct: 764 ALYPFEARNHDEMSFNSGDIIQVDEKTVGEPGWLYGSFQGNFGWFPCNYVEKM 816
Score = 35.0 bits (79), Expect = 0.15
Identities = 16/50 (32%), Positives = 26/50 (52%), Gaps = 5/50 (10%)
Query: 430 YTKDKDDELSFMEGAIIYVIKKNDDGWYEGVC-----NRVTGLFPGNYVE 474
Y ++LS G +I ++KKN GW++G R G FP ++V+
Sbjct: 1064 YVASGSEQLSLAPGQLILILKKNTSGWWQGELQARGKKRQKGWFPASHVK 1113
Score = 33.9 bits (76), Expect = 0.34
Identities = 18/54 (33%), Positives = 32/54 (59%), Gaps = 1/54 (1%)
Query: 423 KVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESI 476
K A+ +T KD+ L+F + II V+++ ++ W+ G + G FP +YV+ I
Sbjct: 902 KAQALCSWTAKKDNHLNFSKHDIITVLEQQENWWF-GEVHGGRGWFPKSYVKII 954
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 62.8 bits (151), Expect = 7e-10
Identities = 70/271 (25%), Positives = 87/271 (32%), Gaps = 67/271 (24%)
Query: 164 QPARTGTLSRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGS- 222
+P+R P ++ PP P G G P E V+ P SPAR GS
Sbjct: 416 EPSRPTDQDYRPPASEAPPPEPPEPGGGGGGGGPSPEREEVRTSPRP----ASPARSGSP 471
Query: 223 ------------QHSP--GRTASLNQRPRTHSGSSGGSGSRENSGSSSI--GIPIAVPTP 266
QHS R L + R+ E SS + P
Sbjct: 472 APETTNESVPFAQHSSLDSRIEMLLKEQRSKFSFLASDTEEEEENSSMVLGARDTGSEVP 531
Query: 267 SPPTIGPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGP 326
S GP P AP + + T S G R +P Q A P +G
Sbjct: 532 SGSGHGPCTPPPAPANFEDV---------APTGSGEPGATRESPKANGQNQASPCSSGDD 582
Query: 327 L-YSQNSISIAPPPPPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPP----------- 374
+ S + +PPP P P P P P PPPPPPP
Sbjct: 583 MEISDDDRGGSPPPAPTPPQQPPPP---------------PPPPPPPPPYLASLPLGYPP 627
Query: 375 ----------DDIPMFDDSPPPPPPPPVDYE 395
D P + PPPPPPPP Y+
Sbjct: 628 HQPAYLLPPRPDGPPPPEYPPPPPPPPHIYD 658
Score = 39.7 bits (91), Expect = 0.006
Identities = 63/240 (26%), Positives = 85/240 (35%), Gaps = 46/240 (19%)
Query: 161 GNNQPARTGTL---SRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSP 217
GN P T SR + P+ P S +GT PY T P + + Y +S
Sbjct: 238 GNGTPCSQDTSFSSSRQDTPSSFGQFTPQSSQGT-----PY-TSRGSTPYSQDSAYSSS- 290
Query: 218 ARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPAAPG 277
T S + +PR S + SR + +SS + T T A
Sbjct: 291 -----------TTSTSFKPRRSENSYQDAFSRRHFSASSASTTAS--TAIAATTAATASS 337
Query: 278 SAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAP 337
SA S +S +S++SS+SS +R S A + A S N
Sbjct: 338 SASSSS-------LSSSSSSSSSSSSSQFR---SSDANYPAYYE-------SWNRYQRHT 380
Query: 338 PPPPMPQLTPQIPLTGFVARVQENIADSPT---PPPPPPPDDI---PMFDDSPPPPPPPP 391
PP + P F E S T PP P P D P ++PPP PP P
Sbjct: 381 SYPPRRATREEPPGAPFAENTAERFPPSYTSYLPPEPSRPTDQDYRPPASEAPPPEPPEP 440
Score = 37.0 bits (84), Expect = 0.040
Identities = 34/127 (26%), Positives = 51/127 (40%), Gaps = 12/127 (9%)
Query: 281 GSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPP 340
G T + S +S++SS+SS + S +++ S++ + S S PPP
Sbjct: 1025 GENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAALPSAS--PPPR 1082
Query: 341 PMPQLTP---QIPLTGFVARV-------QENIADSPTPPPPPPPDDIPMFDDSPPPPPPP 390
+P TP ++P+ VA QE P P P P+ PP PP
Sbjct: 1083 EVPVPTPAPVEVPVPERVAGSPVTPLPEQEASPARPAGPTEESPPSAPLRPPEPPAGPPA 1142
Query: 391 PVDYEDE 397
P DE
Sbjct: 1143 PAPRPDE 1149
Score = 34.3 bits (77), Expect = 0.26
Identities = 47/176 (26%), Positives = 59/176 (33%), Gaps = 33/176 (18%)
Query: 225 SPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGI-----PIAVPTPSPPTIGPAAPGSA 279
S ++S + + S SS S S +S SSS P A+P+ SPP P A
Sbjct: 1031 SDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAALPSASPPPREVPVPTPA 1090
Query: 280 PGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPP 339
P G TP + A P GP ++ S AP
Sbjct: 1091 P--------------VEVPVPERVAGSPVTP--LPEQEASPARPAGP--TEESPPSAPLR 1132
Query: 340 PPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPD-----DIPMFDDSPPPPPPP 390
PP P P P A + SP P PPP + P P PPP
Sbjct: 1133 PPEPPAGPPAP-----APRPDERPSSPIPLLPPPKKRRKTVSFSAIEVVPAPEPPP 1183
>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
Length = 639
Score = 62.4 bits (150), Expect = 9e-10
Identities = 63/228 (27%), Positives = 80/228 (35%), Gaps = 51/228 (22%)
Query: 176 PPTQKPPSPPMS-GRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQ 234
PP +PP PPM+ G G + P PP + Y+ G T +
Sbjct: 422 PPWMQPPPPPMNQGPHPPGHHGP--------PPM--DQYL------------GSTPVGSG 459
Query: 235 RPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPAAPGSA---------PGSQYG 285
R H G G G P P PP GP P P S
Sbjct: 460 VYRLHQGK--GMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSM 517
Query: 286 TMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQL 345
+ + +TT++T+S G P Q +A G P N + PP P L
Sbjct: 518 ASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPL 577
Query: 346 TPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVD 393
P +P PPPPPPP M +PPPPPPPP+D
Sbjct: 578 PP----------------GAPPPPPPPPPGSAGMMY-APPPPPPPPMD 608
Score = 48.9 bits (115), Expect = 1e-05
Identities = 58/245 (23%), Positives = 80/245 (32%), Gaps = 64/245 (26%)
Query: 140 PID-YTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQKPPSPPMSGRGTLGRNTPY 198
P+D Y VG GV L G P G + PP P PP S G P+
Sbjct: 446 PMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPS-----GPLPPW 500
Query: 199 -KTLEPVKPPTVPNDYMTSPARLGSQH------SPGRTASLNQRPRTHSGSSGGSGSREN 251
+ + PP P+ M S L Q + T S+ + + ++ G+ +
Sbjct: 501 QQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQM 560
Query: 252 SGS-SSIGIPIAVPTPSPPTIGPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTP 310
G+ + + +P V P PP P P PGS
Sbjct: 561 QGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGS---------------------------- 592
Query: 311 SVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQ--IPLTGFVARVQENIADSPTP 368
G +Y APPPPP P + P + + G P P
Sbjct: 593 -------------AGMMY-------APPPPPPPPMDPSNFVTMMGMGVAGMPPFGMPPAP 632
Query: 369 PPPPP 373
PPPPP
Sbjct: 633 PPPPP 637
Score = 43.9 bits (102), Expect = 3e-04
Identities = 40/140 (28%), Positives = 46/140 (32%), Gaps = 33/140 (23%)
Query: 272 GPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQN 331
GP PG P S + H + G P P +N GP
Sbjct: 386 GPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNG----PPPPWMQPPPPPMNQGP----- 436
Query: 332 SISIAPP----PPPMPQLTPQIPLTGFVARVQENIADSPTPP------PPPPPDDIPMFD 381
PP PPPM Q P+ V R+ + P PP PPPPP P
Sbjct: 437 ----HPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPP 492
Query: 382 DSPP----------PPPPPP 391
S P PPPPPP
Sbjct: 493 PSGPLPPWQQQQQQPPPPPP 512
Score = 40.4 bits (93), Expect = 0.004
Identities = 58/227 (25%), Positives = 70/227 (30%), Gaps = 42/227 (18%)
Query: 165 PARTGTLSRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGS-Q 223
PA T S P PP S T P+ P + + P G
Sbjct: 335 PATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGP 394
Query: 224 HS-PGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPAAPGS---A 279
HS P SL +G GG + N P P P P GP PG
Sbjct: 395 HSFPHPLPSL-------TGGHGGHPMQHNPNGPPP--PWMQPPPPPMNQGPHPPGHHGPP 445
Query: 280 PGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPP 339
P QY T SG YR G + + + PPP
Sbjct: 446 PMDQYLGST-----------PVGSGVYRLH-------------QGKGMMPPPPMGMMPPP 481
Query: 340 PPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPP 386
PP P P P +G + Q+ PPPPPP M +P P
Sbjct: 482 PPPPSGQPPPPPSGPLPPWQQ----QQQQPPPPPPPSSSMASSTPLP 524
Score = 31.6 bits (70), Expect = 1.7
Identities = 39/140 (27%), Positives = 49/140 (35%), Gaps = 32/140 (22%)
Query: 260 PIAVPTPSPPTIGPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQ 319
P P S P PAAP + P T Q + + S Y
Sbjct: 335 PATTPLASAPR--PAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYH------GMHGGG 386
Query: 320 PHVNGGPLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQENIADSPTPP---PPPPPDD 376
P GGP +S P P+P LT G ++ + P PP PPPPP
Sbjct: 387 P---GGPGGGPHSF-----PHPLPSLTG-----GHGGHPMQHNPNGPPPPWMQPPPPP-- 431
Query: 377 IPMFDDSPPPPP---PPPVD 393
+ P PP PPP+D
Sbjct: 432 ---MNQGPHPPGHHGPPPMD 448
>gi|46094081 development and differentiation enhancing factor 1 [Homo
sapiens]
Length = 1129
Score = 61.6 bits (148), Expect = 2e-09
Identities = 95/359 (26%), Positives = 134/359 (37%), Gaps = 65/359 (18%)
Query: 168 TGTLSRTNPPTQKPPSPPMS-GRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSP 226
T T S T+P T+ PP PP + G+G G P TL P+ T S R P
Sbjct: 778 TSTDSPTSPTTEAPPLPPRNAGKGPTG---PPSTL-PLSTQTSSGSSTLSKKR-PPPPPP 832
Query: 227 G--RTASLNQRPRTHS---------GSSGGSGSRENSGSSSIGIPIAVPTPSPPT-IGPA 274
G RT S P H G+ GG S + + G+ T S T +GP
Sbjct: 833 GHKRTLSDPPSPLPHGPPNKGAVPWGNDGGPSSSSKTTNKFEGLSQQSSTSSAKTALGPR 892
Query: 275 APGSAPGSQYGTMTRQISRHNSTT-------SSTSSGGYRRTPS-----VTAQFSAQPHV 322
P T +S +T SS + ++ P + + +P +
Sbjct: 893 VLPKLPQKVALRKTDHLSLDKATIPPEIFQKSSQLAELPQKPPPGDLPPKPTELAPKPQI 952
Query: 323 NG--------------GPLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQENIADSPTP 368
G L + +S PP P M L P+ L +A+ Q
Sbjct: 953 GDLPPKPGELPPKPQLGDLPPKPQLSDLPPKPQMKDLPPKPQLGDLLAKSQTG----DVS 1008
Query: 369 PPPPPPDDIPMFDDSPPPPPPPPVDYED--EEAAVVQYND--PYADGDPAWAP------K 418
P P ++ + S P P V D ++ A ND P P P K
Sbjct: 1009 PKAQQPSEVTL--KSHPLDLSPNVQSRDAIQKQASEDSNDLTPTLPETPVPLPRKINTGK 1066
Query: 419 NYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWY----EGVCNRVTGLFPGNYV 473
N + +V IYD D DDEL+F+EG +I V + D W+ EG R G+FP ++V
Sbjct: 1067 NKVRRVKTIYDCQADNDDELTFIEGEVIIVTGEEDQEWWIGHIEGQPER-KGVFPVSFV 1124
Score = 32.3 bits (72), Expect = 0.98
Identities = 33/120 (27%), Positives = 40/120 (33%), Gaps = 25/120 (20%)
Query: 272 GPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQN 331
G + P YG T QI ST S TS P PL +N
Sbjct: 755 GFSTPRDKQRLSYGAFTNQIFVSTSTDSPTS-----------------PTTEAPPLPPRN 797
Query: 332 SISIAPPPPPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPPPP 391
+ P PP +PL+ + + S PPPPPP D P P P P
Sbjct: 798 A-GKGPTGPPST-----LPLSTQTSSGSSTL--SKKRPPPPPPGHKRTLSDPPSPLPHGP 849
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 61.2 bits (147), Expect = 2e-09
Identities = 61/225 (27%), Positives = 86/225 (38%), Gaps = 14/225 (6%)
Query: 170 TLSRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRT 229
T + T PP PSPP + T +T TL P P+ P T+P + P T
Sbjct: 1527 TTTTTTPPPTTTPSPPTTTPITPPTSTT--TLPPTTTPSPPPTTTTTPPPTTTPSPPTTT 1584
Query: 230 ASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPAAPGSAPGSQYGTMTR 289
P T + ++ + + +++ P TPSPPT P P ++ + T T
Sbjct: 1585 TP---SPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTP 1641
Query: 290 QISRHNSTT---SSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLT 346
+TT ++T S TPS + P P + I+ P PP T
Sbjct: 1642 SPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTP---SSPITTTPSPPTTTMTT 1698
Query: 347 PQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPPPP 391
P P T + + S T P PPP M SP P PP
Sbjct: 1699 PS-PTTTPSSPITTTTTPSSTTTPSPPPTT--MTTPSPTTTPSPP 1740
Score = 60.1 bits (144), Expect = 4e-09
Identities = 63/249 (25%), Positives = 91/249 (36%), Gaps = 31/249 (12%)
Query: 170 TLSRTNPPTQKPPSPPMSGRGTLGRNT----PYKTLEPVKPPTVPNDYMTSPARLGSQHS 225
T + T PP PSPP++ T T P T P T P+ T+P+ + S
Sbjct: 1426 TTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPS 1485
Query: 226 PGRTASLNQRPRT-------------HSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIG 272
P T + P T S ++ + + +++ P TPSPPT
Sbjct: 1486 PPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTT 1545
Query: 273 PAAPGSAPGSQYGTMTRQISRHNSTT---SSTSSGGYRRTPSVTAQFSAQPHVNGGPLYS 329
P P ++ + T T +TT ++T S TPS + P P
Sbjct: 1546 PITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPP 1605
Query: 330 QNSISIAPP--PPPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPP 387
+ + PP P P TP P T + + TP PPP P +P PP
Sbjct: 1606 TTTTTTPPPTTTPSPPTTTPITPPTS-----TTTLPPTTTPSPPPTTTTTPPPTTTPSPP 1660
Query: 388 ----PPPPV 392
P PP+
Sbjct: 1661 TTTTPSPPI 1669
Score = 55.5 bits (132), Expect = 1e-07
Identities = 59/222 (26%), Positives = 78/222 (35%), Gaps = 28/222 (12%)
Query: 170 TLSRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRT 229
T++ T PP PSPP T TP T P P T P TS L +P
Sbjct: 1590 TITTTTPPPTTTPSPP-----TTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPP 1644
Query: 230 ASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPAAP-GSAPGSQYGTMT 288
+ P + S + +++ PI T PPT P++P + P TMT
Sbjct: 1645 PTTTTTPPPTTTPSPPT-------TTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMT 1697
Query: 289 RQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQ 348
+ TT+ +S TPS T S P P P PP +T
Sbjct: 1698 TP----SPTTTPSSPITTTTTPSSTTTPSPPPTTMTTP------SPTTTPSPPTTTMTTL 1747
Query: 349 IPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPPP 390
P T + +P PP PP P +P P P
Sbjct: 1748 PPTT-----TSSPLTTTPLPPSITPPTFSPFSTTTPTTPCVP 1784
Score = 52.0 bits (123), Expect = 1e-06
Identities = 55/223 (24%), Positives = 74/223 (33%), Gaps = 40/223 (17%)
Query: 171 LSRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTA 230
++ +PPT P PP T TL P P+ P T+P + SP T
Sbjct: 1396 ITTPSPPTTTPSPPP----------TSTTTLPPTTTPSPPTTTTTTPPPTTTP-SPPITT 1444
Query: 231 SLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPAAPGSAPGSQYGTMTRQ 290
+ P T + S+ P TPSPPT P+ P + P
Sbjct: 1445 TTTPPPTT----------TPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPP------- 1487
Query: 291 ISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQIP 350
+TT++T +P T + P + S P P TP P
Sbjct: 1488 -----TTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPP 1542
Query: 351 LTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPP---PPPP 390
T + PT P PPP +PPP P PP
Sbjct: 1543 TTTPITPPTSTTTLPPTTTPSPPPTT----TTTPPPTTTPSPP 1581
Score = 40.8 bits (94), Expect = 0.003
Identities = 39/156 (25%), Positives = 61/156 (39%), Gaps = 9/156 (5%)
Query: 165 PARTGTLSRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTV-PNDYMTSPARLGSQ 223
P T + T PPT P PP + TP T P P T P+ +T+
Sbjct: 1625 PITPPTSTTTLPPTTTPSPPPTT------TTTPPPTTTPSPPTTTTPSPPITTTTTPPPT 1678
Query: 224 HSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPP--TIGPAAPGSAPG 281
+P + P T + ++ + +S ++ P + TPSPP T+ +P + P
Sbjct: 1679 TTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPS 1738
Query: 282 SQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFS 317
TMT S+ +T+ TP + FS
Sbjct: 1739 PPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFS 1774
Score = 39.7 bits (91), Expect = 0.006
Identities = 59/250 (23%), Positives = 94/250 (37%), Gaps = 29/250 (11%)
Query: 165 PARTGTLSRTNPP----TQKPPSPPMSGRGTLGRNTPYKTLEPVKP---PTVPNDYMTSP 217
P TGT + T P T P+P +G T TP T V P PT T+P
Sbjct: 4027 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPTTTP 4085
Query: 218 ARLGSQHSPGRTASLNQRPRTH--------SGSSGGSGSRENSGSSSIGIPIAVPTPSPP 269
+ +P T + Q P T + + +G++ + + PTP+P
Sbjct: 4086 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 4145
Query: 270 TIGPAAPGSAPGSQYGTMTRQIS----RHNSTTSSTSSGGYRRTPSVTAQFSAQP-HVNG 324
G P + P + T+T + + +TT T++ TP+ T + P H +
Sbjct: 4146 --GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTST 4203
Query: 325 GPLYSQNSISIAPPPPPMPQL-----TPQIPLTGFVARVQENIADSPTPPPPPPPDDIPM 379
P+ ++ + S PP PQ +P T ++ + I + T PP P
Sbjct: 4204 API-AELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTT 4262
Query: 380 FDDSPPPPPP 389
PPP
Sbjct: 4263 SGGHTLSPPP 4272
Score = 38.9 bits (89), Expect = 0.010
Identities = 53/242 (21%), Positives = 87/242 (35%), Gaps = 24/242 (9%)
Query: 165 PARTGTLSRTNPP----TQKPPSPPMSGRGTLGRN--TPYKTLEPVKPPTVPNDYMTSPA 218
P TGT + T P T P+P +G T T T+ P PT T+P
Sbjct: 2049 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2108
Query: 219 RLGSQHSPGRTASLNQRPRTH--------SGSSGGSGSRENSGSSSIGIPIAVPTPSPPT 270
+ +P T + Q P T + + +G++ + + PTP+P
Sbjct: 2109 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 2166
Query: 271 IGPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQ 330
G P + P + T+T + + T +T+ T + T + P+
Sbjct: 2167 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI--T 2224
Query: 331 NSISIAPPPPPMPQLTP-QIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPP 389
+ ++ P P P TP P+T + +PTP P P+ + P P
Sbjct: 2225 TTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2279
Query: 390 PP 391
P
Sbjct: 2280 TP 2281
Score = 38.9 bits (89), Expect = 0.010
Identities = 53/242 (21%), Positives = 87/242 (35%), Gaps = 24/242 (9%)
Query: 165 PARTGTLSRTNPP----TQKPPSPPMSGRGTLGRN--TPYKTLEPVKPPTVPNDYMTSPA 218
P TGT + T P T P+P +G T T T+ P PT T+P
Sbjct: 2210 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2269
Query: 219 RLGSQHSPGRTASLNQRPRTH--------SGSSGGSGSRENSGSSSIGIPIAVPTPSPPT 270
+ +P T + Q P T + + +G++ + + PTP+P
Sbjct: 2270 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 2327
Query: 271 IGPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQ 330
G P + P + T+T + + T +T+ T + T + P+
Sbjct: 2328 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI--T 2385
Query: 331 NSISIAPPPPPMPQLTP-QIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPP 389
+ ++ P P P TP P+T + +PTP P P+ + P P
Sbjct: 2386 TTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2440
Query: 390 PP 391
P
Sbjct: 2441 TP 2442
Score = 38.9 bits (89), Expect = 0.010
Identities = 53/242 (21%), Positives = 87/242 (35%), Gaps = 24/242 (9%)
Query: 165 PARTGTLSRTNPP----TQKPPSPPMSGRGTLGRN--TPYKTLEPVKPPTVPNDYMTSPA 218
P TGT + T P T P+P +G T T T+ P PT T+P
Sbjct: 2371 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2430
Query: 219 RLGSQHSPGRTASLNQRPRTH--------SGSSGGSGSRENSGSSSIGIPIAVPTPSPPT 270
+ +P T + Q P T + + +G++ + + PTP+P
Sbjct: 2431 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 2488
Query: 271 IGPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQ 330
G P + P + T+T + + T +T+ T + T + P+
Sbjct: 2489 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI--T 2546
Query: 331 NSISIAPPPPPMPQLTP-QIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPP 389
+ ++ P P P TP P+T + +PTP P P+ + P P
Sbjct: 2547 TTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2601
Query: 390 PP 391
P
Sbjct: 2602 TP 2603
Score = 38.9 bits (89), Expect = 0.010
Identities = 53/242 (21%), Positives = 87/242 (35%), Gaps = 24/242 (9%)
Query: 165 PARTGTLSRTNPP----TQKPPSPPMSGRGTLGRN--TPYKTLEPVKPPTVPNDYMTSPA 218
P TGT + T P T P+P +G T T T+ P PT T+P
Sbjct: 2532 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2591
Query: 219 RLGSQHSPGRTASLNQRPRTH--------SGSSGGSGSRENSGSSSIGIPIAVPTPSPPT 270
+ +P T + Q P T + + +G++ + + PTP+P
Sbjct: 2592 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 2649
Query: 271 IGPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQ 330
G P + P + T+T + + T +T+ T + T + P+
Sbjct: 2650 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI--T 2707
Query: 331 NSISIAPPPPPMPQLTP-QIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPP 389
+ ++ P P P TP P+T + +PTP P P+ + P P
Sbjct: 2708 TTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2762
Query: 390 PP 391
P
Sbjct: 2763 TP 2764
Score = 38.9 bits (89), Expect = 0.010
Identities = 53/242 (21%), Positives = 87/242 (35%), Gaps = 24/242 (9%)
Query: 165 PARTGTLSRTNPP----TQKPPSPPMSGRGTLGRN--TPYKTLEPVKPPTVPNDYMTSPA 218
P TGT + T P T P+P +G T T T+ P PT T+P
Sbjct: 2693 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2752
Query: 219 RLGSQHSPGRTASLNQRPRTH--------SGSSGGSGSRENSGSSSIGIPIAVPTPSPPT 270
+ +P T + Q P T + + +G++ + + PTP+P
Sbjct: 2753 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 2810
Query: 271 IGPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQ 330
G P + P + T+T + + T +T+ T + T + P+
Sbjct: 2811 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI--T 2868
Query: 331 NSISIAPPPPPMPQLTP-QIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPP 389
+ ++ P P P TP P+T + +PTP P P+ + P P
Sbjct: 2869 TTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2923
Query: 390 PP 391
P
Sbjct: 2924 TP 2925
Score = 38.9 bits (89), Expect = 0.010
Identities = 53/242 (21%), Positives = 87/242 (35%), Gaps = 24/242 (9%)
Query: 165 PARTGTLSRTNPP----TQKPPSPPMSGRGTLGRN--TPYKTLEPVKPPTVPNDYMTSPA 218
P TGT + T P T P+P +G T T T+ P PT T+P
Sbjct: 2854 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2913
Query: 219 RLGSQHSPGRTASLNQRPRTH--------SGSSGGSGSRENSGSSSIGIPIAVPTPSPPT 270
+ +P T + Q P T + + +G++ + + PTP+P
Sbjct: 2914 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 2971
Query: 271 IGPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQ 330
G P + P + T+T + + T +T+ T + T + P+
Sbjct: 2972 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI--T 3029
Query: 331 NSISIAPPPPPMPQLTP-QIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPP 389
+ ++ P P P TP P+T + +PTP P P+ + P P
Sbjct: 3030 TTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3084
Query: 390 PP 391
P
Sbjct: 3085 TP 3086
Score = 38.9 bits (89), Expect = 0.010
Identities = 53/242 (21%), Positives = 87/242 (35%), Gaps = 24/242 (9%)
Query: 165 PARTGTLSRTNPP----TQKPPSPPMSGRGTLGRN--TPYKTLEPVKPPTVPNDYMTSPA 218
P TGT + T P T P+P +G T T T+ P PT T+P
Sbjct: 3015 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3074
Query: 219 RLGSQHSPGRTASLNQRPRTH--------SGSSGGSGSRENSGSSSIGIPIAVPTPSPPT 270
+ +P T + Q P T + + +G++ + + PTP+P
Sbjct: 3075 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 3132
Query: 271 IGPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQ 330
G P + P + T+T + + T +T+ T + T + P+
Sbjct: 3133 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI--T 3190
Query: 331 NSISIAPPPPPMPQLTP-QIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPP 389
+ ++ P P P TP P+T + +PTP P P+ + P P
Sbjct: 3191 TTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3245
Query: 390 PP 391
P
Sbjct: 3246 TP 3247
Score = 38.9 bits (89), Expect = 0.010
Identities = 53/242 (21%), Positives = 87/242 (35%), Gaps = 24/242 (9%)
Query: 165 PARTGTLSRTNPP----TQKPPSPPMSGRGTLGRN--TPYKTLEPVKPPTVPNDYMTSPA 218
P TGT + T P T P+P +G T T T+ P PT T+P
Sbjct: 3176 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3235
Query: 219 RLGSQHSPGRTASLNQRPRTH--------SGSSGGSGSRENSGSSSIGIPIAVPTPSPPT 270
+ +P T + Q P T + + +G++ + + PTP+P
Sbjct: 3236 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 3293
Query: 271 IGPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQ 330
G P + P + T+T + + T +T+ T + T + P+
Sbjct: 3294 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI--T 3351
Query: 331 NSISIAPPPPPMPQLTP-QIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPP 389
+ ++ P P P TP P+T + +PTP P P+ + P P
Sbjct: 3352 TTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3406
Query: 390 PP 391
P
Sbjct: 3407 TP 3408
Score = 38.9 bits (89), Expect = 0.010
Identities = 53/242 (21%), Positives = 87/242 (35%), Gaps = 24/242 (9%)
Query: 165 PARTGTLSRTNPP----TQKPPSPPMSGRGTLGRN--TPYKTLEPVKPPTVPNDYMTSPA 218
P TGT + T P T P+P +G T T T+ P PT T+P
Sbjct: 3337 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3396
Query: 219 RLGSQHSPGRTASLNQRPRTH--------SGSSGGSGSRENSGSSSIGIPIAVPTPSPPT 270
+ +P T + Q P T + + +G++ + + PTP+P
Sbjct: 3397 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 3454
Query: 271 IGPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQ 330
G P + P + T+T + + T +T+ T + T + P+
Sbjct: 3455 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI--T 3512
Query: 331 NSISIAPPPPPMPQLTP-QIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPP 389
+ ++ P P P TP P+T + +PTP P P+ + P P
Sbjct: 3513 TTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3567
Query: 390 PP 391
P
Sbjct: 3568 TP 3569
Score = 38.9 bits (89), Expect = 0.010
Identities = 53/242 (21%), Positives = 87/242 (35%), Gaps = 24/242 (9%)
Query: 165 PARTGTLSRTNPP----TQKPPSPPMSGRGTLGRN--TPYKTLEPVKPPTVPNDYMTSPA 218
P TGT + T P T P+P +G T T T+ P PT T+P
Sbjct: 3498 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3557
Query: 219 RLGSQHSPGRTASLNQRPRTH--------SGSSGGSGSRENSGSSSIGIPIAVPTPSPPT 270
+ +P T + Q P T + + +G++ + + PTP+P
Sbjct: 3558 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 3615
Query: 271 IGPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQ 330
G P + P + T+T + + T +T+ T + T + P+
Sbjct: 3616 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI--T 3673
Query: 331 NSISIAPPPPPMPQLTP-QIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPP 389
+ ++ P P P TP P+T + +PTP P P+ + P P
Sbjct: 3674 TTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3728
Query: 390 PP 391
P
Sbjct: 3729 TP 3730
Score = 38.9 bits (89), Expect = 0.010
Identities = 53/242 (21%), Positives = 87/242 (35%), Gaps = 24/242 (9%)
Query: 165 PARTGTLSRTNPP----TQKPPSPPMSGRGTLGRN--TPYKTLEPVKPPTVPNDYMTSPA 218
P TGT + T P T P+P +G T T T+ P PT T+P
Sbjct: 3659 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3718
Query: 219 RLGSQHSPGRTASLNQRPRTH--------SGSSGGSGSRENSGSSSIGIPIAVPTPSPPT 270
+ +P T + Q P T + + +G++ + + PTP+P
Sbjct: 3719 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 3776
Query: 271 IGPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQ 330
G P + P + T+T + + T +T+ T + T + P+
Sbjct: 3777 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI--T 3834
Query: 331 NSISIAPPPPPMPQLTP-QIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPP 389
+ ++ P P P TP P+T + +PTP P P+ + P P
Sbjct: 3835 TTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3889
Query: 390 PP 391
P
Sbjct: 3890 TP 3891
Score = 38.9 bits (89), Expect = 0.010
Identities = 53/242 (21%), Positives = 87/242 (35%), Gaps = 24/242 (9%)
Query: 165 PARTGTLSRTNPP----TQKPPSPPMSGRGTLGRN--TPYKTLEPVKPPTVPNDYMTSPA 218
P TGT + T P T P+P +G T T T+ P PT T+P
Sbjct: 3820 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3879
Query: 219 RLGSQHSPGRTASLNQRPRTH--------SGSSGGSGSRENSGSSSIGIPIAVPTPSPPT 270
+ +P T + Q P T + + +G++ + + PTP+P
Sbjct: 3880 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 3937
Query: 271 IGPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQ 330
G P + P + T+T + + T +T+ T + T + P+
Sbjct: 3938 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI--T 3995
Query: 331 NSISIAPPPPPMPQLTP-QIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPP 389
+ ++ P P P TP P+T + +PTP P P+ + P P
Sbjct: 3996 TTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 4050
Query: 390 PP 391
P
Sbjct: 4051 TP 4052
Score = 37.7 bits (86), Expect = 0.023
Identities = 51/234 (21%), Positives = 80/234 (34%), Gaps = 31/234 (13%)
Query: 165 PARTGTLSRTNPP----TQKPPSPPMSGRGTLGRN--TPYKTLEPVKPPTVPNDYMTSPA 218
P TGT + T P T P+P +G T T T+ P PT T+P
Sbjct: 3981 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 4040
Query: 219 RLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPAAPGS 278
+ +P T + Q P T ++ TP+P G P +
Sbjct: 4041 TTTTTVTPTPTPTGTQTPTTTPITT-----------------TTTVTPTPTPTGTQTPTT 4083
Query: 279 APGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPP 338
P + T+T + + T +T+ T + T + P+ + ++ P
Sbjct: 4084 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI--TTTTTVTPT 4141
Query: 339 PPPMPQLTP-QIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPPPP 391
P P TP P+T + +PTP P P+ + P P P
Sbjct: 4142 PTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 4190
Score = 37.4 bits (85), Expect = 0.030
Identities = 51/243 (20%), Positives = 84/243 (34%), Gaps = 28/243 (11%)
Query: 168 TGTLSRTNPPTQKP----------PSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSP 217
T T PPT P P+P + T T T+ P PT T+P
Sbjct: 1887 TTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 1946
Query: 218 ARLGSQHSPGRTASLNQRPRTH--------SGSSGGSGSRENSGSSSIGIPIAVPTPSPP 269
+ +P T + Q P T + + +G++ + + PTP+P
Sbjct: 1947 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP- 2005
Query: 270 TIGPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYS 329
G P + P + T+T + + T +T+ T + T + P+
Sbjct: 2006 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-- 2062
Query: 330 QNSISIAPPPPPMPQLTP-QIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPP 388
+ ++ P P P TP P+T + +PTP P P+ + P
Sbjct: 2063 TTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2117
Query: 389 PPP 391
P P
Sbjct: 2118 PTP 2120
Score = 35.8 bits (81), Expect = 0.089
Identities = 61/237 (25%), Positives = 81/237 (34%), Gaps = 32/237 (13%)
Query: 165 PARTGT-----LSRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPAR 219
P T T L+ +NPP + S P + R T T TL PP + MTS A
Sbjct: 4198 PTHTSTAPIAELTTSNPPPES--STPQTSRSTSSPLTESTTLLSTLPPAIE---MTSTAP 4252
Query: 220 LGSQHSPGRTA---SLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPA-A 275
+ +P T+ +L+ P T + G +GSSS P V T + P
Sbjct: 4253 PSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPT 4312
Query: 276 PGSAPGSQYGTMTRQISRH-------NSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLY 328
P S P T R N T + Y T T F ++ +
Sbjct: 4313 PLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYF-VNCSLSCTLEF 4371
Query: 329 SQNSISIAPPPPPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPP 385
S P P P P + P + PTP PP + P FD PP
Sbjct: 4372 YNWSCPSTPSPTPTPSKSTPTP------SKPSSTPSKPTPGTKPP--ECPDFD--PP 4418
>gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]
Length = 1220
Score = 60.8 bits (146), Expect = 3e-09
Identities = 26/52 (50%), Positives = 35/52 (67%)
Query: 423 KVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVE 474
+V+ +YDYT DDEL+F +G II V+ K D W++G N GLFP NYV+
Sbjct: 1159 QVIGMYDYTAQNDDELAFNKGQIINVLNKEDPDWWKGEVNGQVGLFPSNYVK 1210
Score = 47.0 bits (110), Expect = 4e-05
Identities = 23/61 (37%), Positives = 34/61 (55%), Gaps = 1/61 (1%)
Query: 413 PAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNY 472
PA P E+ +A+Y Y + +L+F +G +I V KK+ D W+ G G+FP NY
Sbjct: 996 PAAKPVVSGEEFIAMYTYESSEQGDLTFQQGDVILVTKKDGD-WWTGTVGDKAGVFPSNY 1054
Query: 473 V 473
V
Sbjct: 1055 V 1055
Score = 38.9 bits (89), Expect = 0.010
Identities = 23/62 (37%), Positives = 32/62 (51%), Gaps = 7/62 (11%)
Query: 418 KNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVC-----NRVTGLFPGNY 472
K I +V+A YT ++L+ G +I + KKN GW+EG R G FP NY
Sbjct: 1075 KPEIAQVIA--SYTATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANY 1132
Query: 473 VE 474
V+
Sbjct: 1133 VK 1134
Score = 33.9 bits (76), Expect = 0.34
Identities = 18/58 (31%), Positives = 25/58 (43%), Gaps = 7/58 (12%)
Query: 426 AIYDYTKDKDDELSFMEGAIIYV-------IKKNDDGWYEGVCNRVTGLFPGNYVESI 476
A+Y + DE++ G I+ V + + GW G TG FP NY E I
Sbjct: 747 ALYPFESRSHDEITIQPGDIVMVKGEWVDESQTGEPGWLGGELKGKTGWFPANYAEKI 804
Score = 33.5 bits (75), Expect = 0.44
Identities = 17/51 (33%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
Query: 426 AIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESI 476
A+Y + KD+ L+F + +I V+++ D W+ G G FP +YV+ I
Sbjct: 920 ALYPWRAKKDNHLNFNKNDVITVLEQQDMWWF-GEVQGQKGWFPKSYVKLI 969
>gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]
Length = 1721
Score = 60.8 bits (146), Expect = 3e-09
Identities = 26/52 (50%), Positives = 35/52 (67%)
Query: 423 KVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVE 474
+V+ +YDYT DDEL+F +G II V+ K D W++G N GLFP NYV+
Sbjct: 1159 QVIGMYDYTAQNDDELAFNKGQIINVLNKEDPDWWKGEVNGQVGLFPSNYVK 1210
Score = 47.0 bits (110), Expect = 4e-05
Identities = 23/61 (37%), Positives = 34/61 (55%), Gaps = 1/61 (1%)
Query: 413 PAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNY 472
PA P E+ +A+Y Y + +L+F +G +I V KK+ D W+ G G+FP NY
Sbjct: 996 PAAKPVVSGEEFIAMYTYESSEQGDLTFQQGDVILVTKKDGD-WWTGTVGDKAGVFPSNY 1054
Query: 473 V 473
V
Sbjct: 1055 V 1055
Score = 38.9 bits (89), Expect = 0.010
Identities = 23/62 (37%), Positives = 32/62 (51%), Gaps = 7/62 (11%)
Query: 418 KNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVC-----NRVTGLFPGNY 472
K I +V+A YT ++L+ G +I + KKN GW+EG R G FP NY
Sbjct: 1075 KPEIAQVIA--SYTATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANY 1132
Query: 473 VE 474
V+
Sbjct: 1133 VK 1134
Score = 33.9 bits (76), Expect = 0.34
Identities = 18/58 (31%), Positives = 25/58 (43%), Gaps = 7/58 (12%)
Query: 426 AIYDYTKDKDDELSFMEGAIIYV-------IKKNDDGWYEGVCNRVTGLFPGNYVESI 476
A+Y + DE++ G I+ V + + GW G TG FP NY E I
Sbjct: 747 ALYPFESRSHDEITIQPGDIVMVKGEWVDESQTGEPGWLGGELKGKTGWFPANYAEKI 804
Score = 33.5 bits (75), Expect = 0.44
Identities = 17/51 (33%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
Query: 426 AIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESI 476
A+Y + KD+ L+F + +I V+++ D W+ G G FP +YV+ I
Sbjct: 920 ALYPWRAKKDNHLNFNKNDVITVLEQQDMWWF-GEVQGQKGWFPKSYVKLI 969
>gi|224586851 sorbin and SH3 domain containing 2 isoform 6 [Homo
sapiens]
Length = 824
Score = 60.1 bits (144), Expect = 4e-09
Identities = 75/330 (22%), Positives = 117/330 (35%), Gaps = 22/330 (6%)
Query: 156 LKAKHGNNQP-ARTGTLSRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYM 214
L H +N P A S PP PP PP+ R +T +P +
Sbjct: 328 LSKSHSDNSPNAFKDASSPVPPPHVPPPVPPLRPRDR--SSTEKHDWDPPDRKVDTRKFR 385
Query: 215 TSPARLGSQHSPGRTASLNQR-----PRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPP 269
+ P + ++ PG+++ L P T + G R+ SS +G P+P P
Sbjct: 386 SEPRSI-FEYEPGKSSILQHERPPPLPTTPTPVPREPG-RKPLSSSRLGEVTGSPSPPPR 443
Query: 270 TIGPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYS 329
+ P AP + TR + SSG + Q ++
Sbjct: 444 SGAPTPSSRAPAL---SPTRPPKKPLDYVQDHSSGVFNEASLY------QSSIDRSLERP 494
Query: 330 QNSISIAPPPPPMPQLTPQI-PLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPP 388
+S S+A + P + P G + + P F S P P
Sbjct: 495 MSSASMASDFRKRRKSEPAVGPPRGLGDQSASRTSPGRVDLPGSSTTLTKSFTSSSPSSP 554
Query: 389 PPPVDYEDEEAAVVQYNDP--YADGDPAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAII 446
D E + D A + P+ A+YD+ ELSF +G +
Sbjct: 555 SRAKDRESPRSYSSTLTDMGRSAPRERRGTPEKEKLPAKAVYDFKAQTSKELSFKKGDTV 614
Query: 447 YVIKKNDDGWYEGVCNRVTGLFPGNYVESI 476
Y+++K D WYEG + G+FP +YVE +
Sbjct: 615 YILRKIDQNWYEGEHHGRVGIFPISYVEKL 644
Score = 58.2 bits (139), Expect = 2e-08
Identities = 34/96 (35%), Positives = 47/96 (48%), Gaps = 8/96 (8%)
Query: 386 PPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNYI---EKVVAIYDYTKDKDDELSFME 442
P PP P Y + + N P P + +N E A+Y+YT +DEL E
Sbjct: 732 PDPPIPHSYSSDRIHSLSSNKPQR---PVFTHENIQGGGEPFQALYNYTPRNEDELELRE 788
Query: 443 GAIIYVIKKNDDGWYEGVCNRVT--GLFPGNYVESI 476
+I V++K DDGW+ G R G FPGNYV+ +
Sbjct: 789 SDVIDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL 824
Score = 52.4 bits (124), Expect = 9e-07
Identities = 81/342 (23%), Positives = 116/342 (33%), Gaps = 78/342 (22%)
Query: 172 SRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPG--RT 229
SR T P PP SG T P L P +PP P DY+ HS G
Sbjct: 429 SRLGEVTGSPSPPPRSGAPTPSSRAP--ALSPTRPPKKPLDYV-------QDHSSGVFNE 479
Query: 230 ASLNQ--------RPRTHSGSSGGSGSRENSG------------SSSIGIPIAVPTP-SP 268
ASL Q RP + + + R S S+S P V P S
Sbjct: 480 ASLYQSSIDRSLERPMSSASMASDFRKRRKSEPAVGPPRGLGDQSASRTSPGRVDLPGSS 539
Query: 269 PTIGPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLY 328
T+ + S+P S R+ R S+T + R T + P
Sbjct: 540 TTLTKSFTSSSPSSPSRAKDRESPRSYSSTLTDMGRSAPRERRGTPEKEKLPAKAVYDFK 599
Query: 329 SQNSISIAPPPPPMPQLTPQIPLTGFVARVQENIADSP-------TPPPPPPPDDIPMFD 381
+Q S ++ + +I + + P TPP P
Sbjct: 600 AQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVEKLTPPEKAQP------- 652
Query: 382 DSPPPPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNYIEKVVAIYDYTKDKDDELSFM 441
+ PPPP P + I + +A Y++ D + ELS
Sbjct: 653 -ARPPPPAQPGE---------------------------IGEAIAKYNFNADTNVELSLR 684
Query: 442 EGAIIYVIKKNDDGWYEGV---CNRVTGLFPGNYVESIMHYT 480
+G + ++K+ D WYEG NR G+FP +YVE + T
Sbjct: 685 KGDRVILLKRVDQNWYEGKIPGTNR-QGIFPVSYVEVVKKNT 725
Score = 40.8 bits (94), Expect = 0.003
Identities = 47/200 (23%), Positives = 74/200 (37%), Gaps = 27/200 (13%)
Query: 207 PTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTP 266
P N + +P H +T + ++HS +S + +SS P VP P
Sbjct: 300 PYTYNAGLYNPPYSAQSHPAAKTQTYRPLSKSHSDNSPNAFK----DASSPVPPPHVPPP 355
Query: 267 SPPTIGPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGP 326
PP + P S + R++ + S Y S Q P
Sbjct: 356 VPP-LRPRDRSSTEKHDWDPPDRKVDTRKFRSEPRSIFEYEPGKSSILQHERPP------ 408
Query: 327 LYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQENIADSPTPPP----PPPPDDIPMFDD 382
+ P P+P+ + PL+ +R+ E + SP+PPP P P P
Sbjct: 409 -------PLPTTPTPVPREPGRKPLSS--SRLGE-VTGSPSPPPRSGAPTPSSRAPAL-- 456
Query: 383 SPPPPPPPPVDYEDEEAAVV 402
SP PP P+DY + ++ V
Sbjct: 457 SPTRPPKKPLDYVQDHSSGV 476
>gi|224586846 sorbin and SH3 domain containing 2 isoform 4 [Homo
sapiens]
Length = 731
Score = 60.1 bits (144), Expect = 4e-09
Identities = 75/330 (22%), Positives = 117/330 (35%), Gaps = 22/330 (6%)
Query: 156 LKAKHGNNQP-ARTGTLSRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYM 214
L H +N P A S PP PP PP+ R +T +P +
Sbjct: 235 LSKSHSDNSPNAFKDASSPVPPPHVPPPVPPLRPRDR--SSTEKHDWDPPDRKVDTRKFR 292
Query: 215 TSPARLGSQHSPGRTASLNQR-----PRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPP 269
+ P + ++ PG+++ L P T + G R+ SS +G P+P P
Sbjct: 293 SEPRSI-FEYEPGKSSILQHERPPPLPTTPTPVPREPG-RKPLSSSRLGEVTGSPSPPPR 350
Query: 270 TIGPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYS 329
+ P AP + TR + SSG + Q ++
Sbjct: 351 SGAPTPSSRAPAL---SPTRPPKKPLDYVQDHSSGVFNEASLY------QSSIDRSLERP 401
Query: 330 QNSISIAPPPPPMPQLTPQI-PLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPP 388
+S S+A + P + P G + + P F S P P
Sbjct: 402 MSSASMASDFRKRRKSEPAVGPPRGLGDQSASRTSPGRVDLPGSSTTLTKSFTSSSPSSP 461
Query: 389 PPPVDYEDEEAAVVQYNDP--YADGDPAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAII 446
D E + D A + P+ A+YD+ ELSF +G +
Sbjct: 462 SRAKDRESPRSYSSTLTDMGRSAPRERRGTPEKEKLPAKAVYDFKAQTSKELSFKKGDTV 521
Query: 447 YVIKKNDDGWYEGVCNRVTGLFPGNYVESI 476
Y+++K D WYEG + G+FP +YVE +
Sbjct: 522 YILRKIDQNWYEGEHHGRVGIFPISYVEKL 551
Score = 58.2 bits (139), Expect = 2e-08
Identities = 34/96 (35%), Positives = 47/96 (48%), Gaps = 8/96 (8%)
Query: 386 PPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNYI---EKVVAIYDYTKDKDDELSFME 442
P PP P Y + + N P P + +N E A+Y+YT +DEL E
Sbjct: 639 PDPPIPHSYSSDRIHSLSSNKPQR---PVFTHENIQGGGEPFQALYNYTPRNEDELELRE 695
Query: 443 GAIIYVIKKNDDGWYEGVCNRVT--GLFPGNYVESI 476
+I V++K DDGW+ G R G FPGNYV+ +
Sbjct: 696 SDVIDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL 731
Score = 52.4 bits (124), Expect = 9e-07
Identities = 81/342 (23%), Positives = 116/342 (33%), Gaps = 78/342 (22%)
Query: 172 SRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPG--RT 229
SR T P PP SG T P L P +PP P DY+ HS G
Sbjct: 336 SRLGEVTGSPSPPPRSGAPTPSSRAP--ALSPTRPPKKPLDYV-------QDHSSGVFNE 386
Query: 230 ASLNQ--------RPRTHSGSSGGSGSRENSG------------SSSIGIPIAVPTP-SP 268
ASL Q RP + + + R S S+S P V P S
Sbjct: 387 ASLYQSSIDRSLERPMSSASMASDFRKRRKSEPAVGPPRGLGDQSASRTSPGRVDLPGSS 446
Query: 269 PTIGPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLY 328
T+ + S+P S R+ R S+T + R T + P
Sbjct: 447 TTLTKSFTSSSPSSPSRAKDRESPRSYSSTLTDMGRSAPRERRGTPEKEKLPAKAVYDFK 506
Query: 329 SQNSISIAPPPPPMPQLTPQIPLTGFVARVQENIADSP-------TPPPPPPPDDIPMFD 381
+Q S ++ + +I + + P TPP P
Sbjct: 507 AQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVEKLTPPEKAQP------- 559
Query: 382 DSPPPPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNYIEKVVAIYDYTKDKDDELSFM 441
+ PPPP P + I + +A Y++ D + ELS
Sbjct: 560 -ARPPPPAQPGE---------------------------IGEAIAKYNFNADTNVELSLR 591
Query: 442 EGAIIYVIKKNDDGWYEGV---CNRVTGLFPGNYVESIMHYT 480
+G + ++K+ D WYEG NR G+FP +YVE + T
Sbjct: 592 KGDRVILLKRVDQNWYEGKIPGTNR-QGIFPVSYVEVVKKNT 632
Score = 40.8 bits (94), Expect = 0.003
Identities = 47/200 (23%), Positives = 74/200 (37%), Gaps = 27/200 (13%)
Query: 207 PTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTP 266
P N + +P H +T + ++HS +S + +SS P VP P
Sbjct: 207 PYTYNAGLYNPPYSAQSHPAAKTQTYRPLSKSHSDNSPNAFK----DASSPVPPPHVPPP 262
Query: 267 SPPTIGPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGP 326
PP + P S + R++ + S Y S Q P
Sbjct: 263 VPP-LRPRDRSSTEKHDWDPPDRKVDTRKFRSEPRSIFEYEPGKSSILQHERPP------ 315
Query: 327 LYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQENIADSPTPPP----PPPPDDIPMFDD 382
+ P P+P+ + PL+ +R+ E + SP+PPP P P P
Sbjct: 316 -------PLPTTPTPVPREPGRKPLSS--SRLGE-VTGSPSPPPRSGAPTPSSRAPAL-- 363
Query: 383 SPPPPPPPPVDYEDEEAAVV 402
SP PP P+DY + ++ V
Sbjct: 364 SPTRPPKKPLDYVQDHSSGV 383
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 60.1 bits (144), Expect = 4e-09
Identities = 61/220 (27%), Positives = 82/220 (37%), Gaps = 32/220 (14%)
Query: 175 NPPTQKPPSPPMSGRGTLGRNTP-YKTLEPVK-PPTVPNDYMTSPARLGSQHSPGRTA-S 231
+PP Q PSPP+S T P L P++ PP+ P SP S +P A
Sbjct: 600 SPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVH 659
Query: 232 LNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPAAPGSAPGSQYGTMTRQI 291
L Q P + S P+ P SPP P +P + P SQ +
Sbjct: 660 LLQAPFSPPPSP----------------PVQAPF-SPPASPPVSPSATPPSQ---APPSL 699
Query: 292 SRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQIPL 351
+ + +PS T A P + PL + P PP P ++P
Sbjct: 700 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPL------QVPPSPPASPPMSPSATP 753
Query: 352 TGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPPPP 391
RV +A P PP PP +PM + PPP PP
Sbjct: 754 P---PRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPP 790
Score = 54.7 bits (130), Expect = 2e-07
Identities = 67/246 (27%), Positives = 93/246 (37%), Gaps = 29/246 (11%)
Query: 167 RTGTLSRTNPPTQKPPS--PPMSGRGTLGRNTPYKTLEPVKPPT---VPNDYMTSPARLG 221
+T S T PP + PS PP + TP+ P P P +T+P
Sbjct: 524 QTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTP---- 579
Query: 222 SQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTP-SPPTIG-------P 273
P T S P + + S + S + P+A P P +PP + P
Sbjct: 580 ----PPETPSSIATPPPQAPPALASPPLQGLPSPPLS-PLATPPPQAPPXLALPPLQAPP 634
Query: 274 AAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFS--AQPHVNGGPLY-SQ 330
+ P S P S T + Q + + +P V A FS A P V+ SQ
Sbjct: 635 SPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQ 694
Query: 331 NSISIAPPP---PPMPQLTPQI-PLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPP 386
S+A PP PP P +P + P + +A P PP PP PM + PP
Sbjct: 695 APPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPP 754
Query: 387 PPPPPV 392
P PP+
Sbjct: 755 PRVPPL 760
Score = 48.1 bits (113), Expect = 2e-05
Identities = 59/245 (24%), Positives = 83/245 (33%), Gaps = 35/245 (14%)
Query: 169 GTLSRTNPPTQKPPSPPMSGR----GT-LGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQ 223
G T+ PT PSP M+ R GT +G P + P P P ++S S+
Sbjct: 159 GARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSS----ASE 214
Query: 224 HSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPAAPGSAPGSQ 283
HS + +R + G SR S S A P SP GP+A G+
Sbjct: 215 HSTTEPSPAARRRPSAGGGLQRPASRSLSSS-------ATPLSSPARSGPSARGTPRAPA 267
Query: 284 YGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPP---- 339
+ + + + P++ S+ P P S PPP
Sbjct: 268 HPSQPKPKGLQALRPPQVTPPRKDAAPAL-GPLSSSPLATPSP--SGTKARPVPPPDNAA 324
Query: 340 -------PPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPP--- 389
PP P L +PL ++ P+PP PP P P PP
Sbjct: 325 TPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQ 384
Query: 390 --PPV 392
PP+
Sbjct: 385 TIPPI 389
Score = 44.3 bits (103), Expect = 2e-04
Identities = 63/223 (28%), Positives = 82/223 (36%), Gaps = 37/223 (16%)
Query: 176 PPTQKPPSPP----MSGRGTLG-RNTPYKTLEPVK-PPTVPNDYMTSPARLGSQHSPGRT 229
PP Q PPSPP MS T R P P++ PP+ P SP +P
Sbjct: 733 PPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPAL 792
Query: 230 AS--LNQRPRTHSGSSGGSGSRENSGSSSIGI-PIAVPTPSPPTIGPAAPGSAPGSQYGT 286
A+ L P S + G S S+S+ + P+A P P P + A P S +
Sbjct: 793 ATPPLQALP---SPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPAS 849
Query: 287 MTRQISRHNSTTS-STSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQL 345
T Q R T TS G R T +++AP PPP P
Sbjct: 850 PTLQAPRRPPTPGPDTSVSGPRLT-----------------------LALAPGPPPPPSR 886
Query: 346 TPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPP 388
+P L+G + A S TP D P + PPP
Sbjct: 887 SPSSTLSGPDLAGHSSSATS-TPEELRGYDSGPEGGAAASPPP 928
Score = 42.7 bits (99), Expect = 7e-04
Identities = 64/280 (22%), Positives = 87/280 (31%), Gaps = 62/280 (22%)
Query: 167 RTGTLSRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSP 226
R G + P P + P GT RN + + P TSP G SP
Sbjct: 61 RAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSP---GPVSSP 117
Query: 227 GRTASLNQRP-----------------------------------RTHSGSSGGSGS--- 248
GR AS RP R SG + G+ S
Sbjct: 118 GR-ASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAM 176
Query: 249 --RENSGSSSIGIPIAVPT--PSPPTIGPAAPGSAPG---------------SQYGTMTR 289
R + + +G+P P+ P PPT GP S+ S G + R
Sbjct: 177 ARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQR 236
Query: 290 QISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQI 349
SR S++++ S R PS A H + ++ PP P +
Sbjct: 237 PASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPAL 296
Query: 350 -PLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPP 388
PL+ P PPP P+ PP PP
Sbjct: 297 GPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPP 336
Score = 37.4 bits (85), Expect = 0.030
Identities = 56/241 (23%), Positives = 84/241 (34%), Gaps = 35/241 (14%)
Query: 163 NQPARTGTLSRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGS 222
+ PAR+G +R P PS P K L+ ++PP V +P R +
Sbjct: 250 SSPARSGPSARGTPRAPAHPSQPKP-----------KGLQALRPPQV------TPPRKDA 292
Query: 223 QHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPAAPGSAPGS 282
+ G +S + SG+ ++ ++ + P +P PSPP P AP S
Sbjct: 293 APALGPLSSSPLATPSPSGTKARPVPPPDNAATPL--PATLP-PSPPLATPLP--LAPPS 347
Query: 283 QYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPM 342
+ Q T + + TP + A S Q +S S S+ PP P+
Sbjct: 348 PSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPL 407
Query: 343 -------------PQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPP 389
P L R + SP+ P PPD P+ P P
Sbjct: 408 ALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASP 467
Query: 390 P 390
P
Sbjct: 468 P 468
>gi|51988887 SH3 domain containing ring finger 1 [Homo sapiens]
Length = 888
Score = 59.7 bits (143), Expect = 6e-09
Identities = 50/185 (27%), Positives = 75/185 (40%), Gaps = 17/185 (9%)
Query: 296 STTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQIPLTGFV 355
S+++ T++ ++ +Q H++ L I PPP P T P F
Sbjct: 333 SSSNPTAAARISELSGLSCSAPSQVHISTTGL-------IVTPPPSSPVTTG--PSFTFP 383
Query: 356 ARVQENIADSPTPPPPPPPDDIP--MFDDSPPPPPPPPVDYEDEEAAVVQYNDPYADGDP 413
+ V A PP PPP + + +PP + D A P
Sbjct: 384 SDVPYQAALGTLNPPLPPPPLLAATVLASTPPGATAAAAAAGMGPRPMAGSTDQIAHLRP 443
Query: 414 AWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVT--GLFPGN 471
P Y VAIY YT K+DEL +G + V ++ DGW++G + G+FPGN
Sbjct: 444 QTRPSVY----VAIYPYTPRKEDELELRKGEMFLVFERCQDGWFKGTSMHTSKIGVFPGN 499
Query: 472 YVESI 476
YV +
Sbjct: 500 YVAPV 504
Score = 53.1 bits (126), Expect = 5e-07
Identities = 71/316 (22%), Positives = 110/316 (34%), Gaps = 49/316 (15%)
Query: 191 TLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRE 250
T+ + + V P V N SPA +G H AS P ++ +
Sbjct: 592 TVAAHNQERPTAAVTPIQVQNAAGLSPASVGLSHHS--LASPQPAPLMPGSATHTAAISI 649
Query: 251 NSGSSSIGIPIAVPTPSPPTIGPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTP 310
+ S+ + A P SP +I A+ + P + T+ + + SS P
Sbjct: 650 SRASAPLACAAAAPLTSP-SITSASLEAEPSGRIVTVLPGLPTSPDSASSACGNSSATKP 708
Query: 311 SVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQENIADSPTPPP 370
++ + G L + S P P +P + + A + A P PP
Sbjct: 709 DKDSKKEKK-----GLLKLLSGASTKRKPRVSPPASPTLEVELGSAELPLQGAVGPELPP 763
Query: 371 P---------PPPDDIPMFD-------------------DSPPPPPPPPVDYEDEEAAVV 402
P D P+ DS P PPP V+
Sbjct: 764 GGGHGRAGSCPVDGDGPVTTAVAGAALAQDAFHRKASSLDSAVPIAPPPRQACSSLGPVL 823
Query: 403 QYNDPYADGDPAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCN 462
+ P E+ + Y + EL EG I++V KK +DGW++G
Sbjct: 824 NESRPVV-----------CERHRVVVSYPPQSEAELELKEGDIVFVHKKREDGWFKGTLQ 872
Query: 463 R--VTGLFPGNYVESI 476
R TGLFPG++VE+I
Sbjct: 873 RNGKTGLFPGSFVENI 888
Score = 45.1 bits (105), Expect = 1e-04
Identities = 19/51 (37%), Positives = 31/51 (60%)
Query: 426 AIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESI 476
A+Y+Y + +L F +G II + ++ D+ WY G N + G FP N+V+ I
Sbjct: 141 ALYNYEGKEPGDLKFSKGDIIILRRQVDENWYHGEVNGIHGFFPTNFVQII 191
Score = 38.9 bits (89), Expect = 0.010
Identities = 21/53 (39%), Positives = 33/53 (62%), Gaps = 4/53 (7%)
Query: 426 AIYDY-TKDKD---DELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVE 474
A+YD+ KDK+ D L F + ++ VI++ D+ W EG+ G+FP +YVE
Sbjct: 203 ALYDFEVKDKEADKDCLPFAKDDVLTVIRRVDENWAEGMLADKIGIFPISYVE 255
>gi|167234422 hematopoietic cell-specific Lyn substrate 1 [Homo
sapiens]
Length = 486
Score = 59.7 bits (143), Expect = 6e-09
Identities = 43/154 (27%), Positives = 64/154 (41%), Gaps = 37/154 (24%)
Query: 358 VQENIADSPTPPPPPPP--------DDIPMFDDSPPPPPPPPV----DYEDEEAAVVQYN 405
+++ + + PP PP ++ P+++ P P P P DYED E
Sbjct: 330 IRQTLPEDNEEPPALPPRTLEGLQVEEEPVYEAEPEPEPEPEPEPENDYEDVEEMDRHEQ 389
Query: 406 DPYADGD----------------------PAWAPKNYIE---KVVAIYDYTKDKDDELSF 440
+ +GD PA A + VA+YDY + DELSF
Sbjct: 390 EDEPEGDYEEVLEPEDSSFSSALAGSSGCPAGAGAGAVALGISAVALYDYQGEGSDELSF 449
Query: 441 MEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVE 474
+I I+ D+GW+ G C+ GLFP NYV+
Sbjct: 450 DPDDVITDIEMVDEGWWRGRCHGHFGLFPANYVK 483
>gi|55956916 myosin IE [Homo sapiens]
Length = 1108
Score = 59.3 bits (142), Expect = 7e-09
Identities = 63/248 (25%), Positives = 95/248 (38%), Gaps = 38/248 (15%)
Query: 241 GSSGGSGSRENSGSSSIGIPIAVPTPSPP----TIGPAAPGSAPGSQYGTMTRQISRHNS 296
G GSR+ G +AV PS +IGP P ++ ++ T Q + ++S
Sbjct: 887 GPWSAGGSRQVQFHQGFG-DLAVLKPSNKVLQVSIGPGLPKNSRPTRRNTT--QNTGYSS 943
Query: 297 TTSSTS--------SGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQ 348
T + + GY + + Q+ PH G +Q S+ + PP+P+ Q
Sbjct: 944 GTQNANYPVRAAPPPPGYHQNGVIRNQYVPYPHAPGSQRSNQKSLYTSMARPPLPR--QQ 1001
Query: 349 IPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYNDPY 408
+ V++ E++ D P PPP P
Sbjct: 1002 STSSDRVSQTPESL-DFLKVPDQGAAGVRRQTTSRPPPAGGRP----------------- 1043
Query: 409 ADGDPAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLF 468
P PK + + A+Y Y DELSF II +IK++ GW+ G GLF
Sbjct: 1044 ---KPQPKPKPQVPQCKALYAYDAQDTDELSFNANDIIDIIKEDPSGWWTGRLRGKQGLF 1100
Query: 469 PGNYVESI 476
P NYV I
Sbjct: 1101 PNNYVTKI 1108
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 58.9 bits (141), Expect = 1e-08
Identities = 67/244 (27%), Positives = 99/244 (40%), Gaps = 36/244 (14%)
Query: 163 NQPARTGTLSRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGS 222
+ PAR+G +R P PS P K L+ ++PP V + LG
Sbjct: 250 SSPARSGPSARGTPRAPAHPSQPKP-----------KGLQALRPPQVTPPRKDAAPALGP 298
Query: 223 QHS-----PGRTASL-NQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPS-PPTI---- 271
S P +A+L +Q P T + S + + +P+A P+PS PP++
Sbjct: 299 LSSSPLATPSPSAALQSQAPPTLPATPHSSSL---TCQLATPLPLAPPSPSAPPSLQTLP 355
Query: 272 -GPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQ 330
PA P S + G+ T Q + H+ S S P T A P + PL +
Sbjct: 356 SPPATPPSQATTSLGSPTLQ-ATHSFLPSPPLS------PLATPPPQAPPALALPPLQAP 408
Query: 331 NSISIAPPPPPMPQLTPQIPLTGFVARVQENIADSPTPP---PPPPPDDIPMFDDSPPPP 387
S +PP P+ +PQ P V +Q + P+PP P PP P+ + PP
Sbjct: 409 PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPS 468
Query: 388 PPPP 391
PP
Sbjct: 469 QAPP 472
Score = 52.0 bits (123), Expect = 1e-06
Identities = 67/260 (25%), Positives = 94/260 (36%), Gaps = 37/260 (14%)
Query: 169 GTLSRTNPPTQKPPSPPMSGR----GT-LGRNTPYKTLEPVKPPTVP-------NDYMTS 216
G T+ PT PSP M+ R GT +G P + P P P +++ T+
Sbjct: 159 GARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTT 218
Query: 217 PARLGSQHSPGRTASLNQRPRTHSGSSGGS--GSRENSGSSSIGIPIAVPTPS------- 267
++ P L QRP + S SS + S SG S+ G P A PS
Sbjct: 219 EPSPAARRRPSAGGGL-QRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGL 277
Query: 268 ----PPTIGP----AAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQ 319
PP + P AAP P S T S + + + + S+T Q +
Sbjct: 278 QALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATP 337
Query: 320 PHVNGGPLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQENIADSP------TPPPPPP 373
+ + S+ P PP P L + + SP TPPP P
Sbjct: 338 LPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAP 397
Query: 374 PD-DIPMFDDSPPPPPPPPV 392
P +P P PP PP+
Sbjct: 398 PALALPPLQAPPSPPASPPL 417
Score = 51.2 bits (121), Expect = 2e-06
Identities = 69/242 (28%), Positives = 97/242 (40%), Gaps = 42/242 (17%)
Query: 165 PARTGTLSRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQH 224
P+ + L PPT P+ P S T TP P+ PP+ ++P L +
Sbjct: 307 PSPSAALQSQAPPTL--PATPHSSSLTCQLATPL----PLAPPSP-----SAPPSLQTLP 355
Query: 225 SPGRTASLNQRPRTHSGSSGGSGSRENSGS---SSIGIPIAVPTP-SPPTIG-------P 273
SP T P + + +S GS + + + S S P+A P P +PP + P
Sbjct: 356 SPPAT------PPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPP 409
Query: 274 AAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFS--AQPHVNGGPLY-SQ 330
+ P S P S T + Q + + +P V A FS A P V+ SQ
Sbjct: 410 SPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQ 469
Query: 331 NSISIAPPPPPMPQLTPQIPLTGFVARVQENIADSPTPPPP-PPPDDIPMFDDSPPPPPP 389
S+A PP +P P P ++ S TPPP PPP P + PPP
Sbjct: 470 APPSLAAPPLQVPPSPPASP----------PMSPSATPPPQAPPPLAAPPLQLAKPPPQA 519
Query: 390 PP 391
PP
Sbjct: 520 PP 521
Score = 47.0 bits (110), Expect = 4e-05
Identities = 72/307 (23%), Positives = 97/307 (31%), Gaps = 87/307 (28%)
Query: 167 RTGTLSRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSP 226
R G + P P + P GT RN + + P TSP G SP
Sbjct: 61 RAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSP---GPVSSP 117
Query: 227 GRTASLNQRP-----------------------------------RTHSGSSGGSGS--- 248
GR AS RP R SG + G+ S
Sbjct: 118 GR-ASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAM 176
Query: 249 --RENSGSSSIGIPIAVPT--PSPPTIGPAAPGSAPG---------------SQYGTMTR 289
R + + +G+P P+ P PPT GP S+ S G + R
Sbjct: 177 ARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQR 236
Query: 290 QISRHNSTTSSTSSGGYRRTPSV-----TAQFSAQPHVNG-------------------- 324
SR S++++ S R PS +QP G
Sbjct: 237 PASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPAL 296
Query: 325 GPLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSP 384
GPL S + +P Q P +P T + + +A +P P PP P P P
Sbjct: 297 GPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLA-TPLPLAPPSPSAPPSLQTLP 355
Query: 385 PPPPPPP 391
PP PP
Sbjct: 356 SPPATPP 362
Score = 46.6 bits (109), Expect = 5e-05
Identities = 62/235 (26%), Positives = 81/235 (34%), Gaps = 37/235 (15%)
Query: 165 PARTGTLSRTNPPTQKP----PSPPMSGRGTLGRNTPYK-TLEPVK-PPTVPNDYMTSPA 218
P T S +P Q PSPP+S T P L P++ PP+ P SP
Sbjct: 361 PPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPL 420
Query: 219 RLGSQHSPGRTA-SLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPAAPG 277
S +P A L Q P + S P+ P SPP P +P
Sbjct: 421 ATPSPQAPNALAVHLLQAPFSPPPSP----------------PVQAPF-SPPASPPVSPS 463
Query: 278 SAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAP 337
+ P SQ ++ + +PS T A P + PL +A
Sbjct: 464 ATPPSQ---APPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPL------QLAK 514
Query: 338 PPPPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPPPPV 392
PPP P PL + A P P P +PM + PPP PPV
Sbjct: 515 PPPQAPPALATPPLQALPSPP----ASFPGQAPFSPSASLPMSPLATPPPQAPPV 565
Score = 45.1 bits (105), Expect = 1e-04
Identities = 59/217 (27%), Positives = 77/217 (35%), Gaps = 38/217 (17%)
Query: 176 PPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQR 235
PP Q PPSPP S P + PP P P +L ++ P +L
Sbjct: 477 PPLQVPPSPPAS---------PPMSPSATPPPQAPPPLAAPPLQL-AKPPPQAPPALATP 526
Query: 236 PRTHSGSSGGS--GSRENSGSSSIGI-PIAVPTPSPPTIGPAAPGSAPGSQYGTMTRQIS 292
P S S G S S+S+ + P+A P P P + A P S + T Q
Sbjct: 527 PLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAP 586
Query: 293 RHNSTTS-STSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQIPL 351
R T TS G R T +++AP PPP P +P L
Sbjct: 587 RRPPTPGPDTSVSGPRLT-----------------------LALAPGPPPPPSRSPSSTL 623
Query: 352 TGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPP 388
+G + A S TP D P + PPP
Sbjct: 624 SGPDLAGHSSSATS-TPEELRGYDSGPEGGAAASPPP 659
>gi|150417989 cyclin K isoform 1 [Homo sapiens]
Length = 580
Score = 58.9 bits (141), Expect = 1e-08
Identities = 67/237 (28%), Positives = 86/237 (36%), Gaps = 33/237 (13%)
Query: 177 PTQKPPSPPMSGRGTL-GRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQR 235
P+ +P SP R + K EP PP +P T P + P R L
Sbjct: 323 PSPQPSSPRQVKRAVVVSPKEENKAAEP-PPPKIPKIETTHPPLPPAHPPPDRKPPL--- 378
Query: 236 PRTHSGSSGGSGSRENSGSSSIGIPIAV---PTPSPPTIGPAAPGSAPGSQYGTMTRQIS 292
G + G + + + IP P PP + P P P S Y T
Sbjct: 379 -AAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPL-PHRPPPPPPSSYMTGM---- 432
Query: 293 RHNSTTSSTSSG-GYRRTPSVTA----QFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTP 347
STTSS SG GY+ S+ + A P G P + + PP PP P + P
Sbjct: 433 ---STTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPPPPVPP 489
Query: 348 QIPLTGFVARVQENIADSPTPPP------PPPPDDIPMFDDSPPPPPP----PPVDY 394
P + + P PPP PPPP +P PP PPP PP Y
Sbjct: 490 P-PASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPPASY 545
Score = 39.7 bits (91), Expect = 0.006
Identities = 63/297 (21%), Positives = 98/297 (32%), Gaps = 43/297 (14%)
Query: 140 PIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQKPPSPPMSGRGTLGRNTPYK 199
P+D VL+D+ H + L ++ P T + P Q P P + ++ P +
Sbjct: 243 PVD--VLEDICHQILDLYSQGKQQMPHHTPHQLQQPPSLQPTPQVPQ-----VQQSQPSQ 295
Query: 200 TLEPVKP----PTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSS 255
+ EP +P P P PA+ + SP ++ PR + S EN +
Sbjct: 296 SSEPSQPQQKDPQQPAQQQ-QPAQQPKKPSPQPSS-----PRQVKRAVVVSPKEENKAAE 349
Query: 256 SIGIPIAVPTPSPPTIGPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQ 315
P P P I P P ++ P V
Sbjct: 350 P-------PPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIP 402
Query: 316 FSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQIPLT-------GFVARVQENIADSPT- 367
A P P++ + PPPPP + T G+ + + P+
Sbjct: 403 PPAHP----APVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSY 458
Query: 368 ---PPPPPPPDDIP----MFDDSPPPPPPPPVDYEDEEAAVVQYNDPYADGDPAWAP 417
PP PP +P ++ +PPPPP PP A+ Y P + P
Sbjct: 459 GALPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNP 515
Score = 37.0 bits (84), Expect = 0.040
Identities = 28/95 (29%), Positives = 36/95 (37%), Gaps = 8/95 (8%)
Query: 326 PLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPP 385
P Q P P P Q+ V+ +EN A P PP IP + + P
Sbjct: 310 PAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPK------IPKIETTHP 363
Query: 386 PPPP--PPVDYEDEEAAVVQYNDPYADGDPAWAPK 418
P PP PP D + AA + +P D PK
Sbjct: 364 PLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPK 398
>gi|224586855 sorbin and SH3 domain containing 2 isoform 8 [Homo
sapiens]
Length = 492
Score = 58.2 bits (139), Expect = 2e-08
Identities = 34/96 (35%), Positives = 47/96 (48%), Gaps = 8/96 (8%)
Query: 386 PPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNYI---EKVVAIYDYTKDKDDELSFME 442
P PP P Y + + N P P + +N E A+Y+YT +DEL E
Sbjct: 400 PDPPIPHSYSSDRIHSLSSNKPQR---PVFTHENIQGGGEPFQALYNYTPRNEDELELRE 456
Query: 443 GAIIYVIKKNDDGWYEGVCNRVT--GLFPGNYVESI 476
+I V++K DDGW+ G R G FPGNYV+ +
Sbjct: 457 SDVIDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL 492
Score = 52.8 bits (125), Expect = 7e-07
Identities = 64/287 (22%), Positives = 97/287 (33%), Gaps = 31/287 (10%)
Query: 207 PTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTP 266
P N + +P H +T + ++HS +S + +SS P VP P
Sbjct: 40 PYTYNAGLYNPPYSAQSHPAAKTQTYRPLSKSHSDNSPNAFK----DASSPVPPPHVPPP 95
Query: 267 SPPTIGPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGP 326
PP + P S + R++ + S Y S Q H
Sbjct: 96 VPP-LRPRDRSSTEKHDWDPPDRKVDTRKFRSEPRSIFEYEPGKSSILQ-----HERPAS 149
Query: 327 LYS-------QNSISIAPPPPPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIP- 378
LY + +S A + P G + D P D+P
Sbjct: 150 LYQSSIDRSLERPMSSASMASDFRKRRKSEPAVG----PPRGLGDQSASRTSPGRVDLPG 205
Query: 379 -------MFDDSPPPPPPPPVDYEDEEAAVVQYNDP--YADGDPAWAPKNYIEKVVAIYD 429
F S P P D E + D A + P+ A+YD
Sbjct: 206 SSTTLTKSFTSSSPSSPSRAKDRESPRSYSSTLTDMGRSAPRERRGTPEKEKLPAKAVYD 265
Query: 430 YTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESI 476
+ ELSF +G +Y+++K D WYEG + G+FP +YVE +
Sbjct: 266 FKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVEKL 312
Score = 47.8 bits (112), Expect = 2e-05
Identities = 81/368 (22%), Positives = 131/368 (35%), Gaps = 85/368 (23%)
Query: 156 LKAKHGNNQP-ARTGTLSRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYM 214
L H +N P A S PP PP PP+ R +T +P +
Sbjct: 68 LSKSHSDNSPNAFKDASSPVPPPHVPPPVPPLRPRDR--SSTEKHDWDPPDRKVDTRKFR 125
Query: 215 TSPARLGSQHSPGRTASL-NQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGP 273
+ P + ++ PG+++ L ++RP + SS S+S+ S P +GP
Sbjct: 126 SEPRSI-FEYEPGKSSILQHERPASLYQSSIDRSLERPMSSASMASDFRKRRKSEPAVGP 184
Query: 274 -----------AAPGSA--PGSQYGTMTRQISRHNSTTSSTSSGGYRRTP-----SVTAQ 315
+PG PGS T+T+ + +S+ SS S R +P ++T
Sbjct: 185 PRGLGDQSASRTSPGRVDLPGSST-TLTKSFT--SSSPSSPSRAKDRESPRSYSSTLTDM 241
Query: 316 FSAQPHVNGGP-------------LYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQENI 362
+ P G +Q S ++ + +I + +
Sbjct: 242 GRSAPRERRGTPEKEKLPAKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRV 301
Query: 363 ADSP-------TPPPPPPPDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYNDPYADGDPAW 415
P TPP P + PPPP P +
Sbjct: 302 GIFPISYVEKLTPPEKAQP--------ARPPPPAQPGE---------------------- 331
Query: 416 APKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGV---CNRVTGLFPGNY 472
I + +A Y++ D + ELS +G + ++K+ D WYEG NR G+FP +Y
Sbjct: 332 -----IGEAIAKYNFNADTNVELSLRKGDRVILLKRVDQNWYEGKIPGTNR-QGIFPVSY 385
Query: 473 VESIMHYT 480
VE + T
Sbjct: 386 VEVVKKNT 393
>gi|224586853 sorbin and SH3 domain containing 2 isoform 7 [Homo
sapiens]
Length = 1004
Score = 58.2 bits (139), Expect = 2e-08
Identities = 34/96 (35%), Positives = 47/96 (48%), Gaps = 8/96 (8%)
Query: 386 PPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNYI---EKVVAIYDYTKDKDDELSFME 442
P PP P Y + + N P P + +N E A+Y+YT +DEL E
Sbjct: 912 PDPPIPHSYSSDRIHSLSSNKPQR---PVFTHENIQGGGEPFQALYNYTPRNEDELELRE 968
Query: 443 GAIIYVIKKNDDGWYEGVCNRVT--GLFPGNYVESI 476
+I V++K DDGW+ G R G FPGNYV+ +
Sbjct: 969 SDVIDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL 1004
Score = 51.6 bits (122), Expect = 2e-06
Identities = 21/51 (41%), Positives = 32/51 (62%)
Query: 426 AIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESI 476
A+YD+ ELSF +G +Y+++K D WYEG + G+FP +YVE +
Sbjct: 774 AVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVEKL 824
Score = 42.4 bits (98), Expect = 0.001
Identities = 25/71 (35%), Positives = 38/71 (53%), Gaps = 4/71 (5%)
Query: 413 PAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGV---CNRVTGLFP 469
P A I + +A Y++ D + ELS +G + ++K+ D WYEG NR G+FP
Sbjct: 836 PPPAQPGEIGEAIAKYNFNADTNVELSLRKGDRVILLKRVDQNWYEGKIPGTNR-QGIFP 894
Query: 470 GNYVESIMHYT 480
+YVE + T
Sbjct: 895 VSYVEVVKKNT 905
Score = 33.5 bits (75), Expect = 0.44
Identities = 38/165 (23%), Positives = 64/165 (38%), Gaps = 19/165 (11%)
Query: 156 LKAKHGNNQPARTGTLSRTNPPTQKPPS-PPMSGRGTLGRNTPYKTLEPVKPPTVPNDYM 214
L H +N P S PP PP PP+ R +T +P +
Sbjct: 53 LSKSHSDNSPNAFKDASSPVPPPHVPPPVPPLRPRDR--SSTEKHDWDPPDRKVDTRKFR 110
Query: 215 TSPARLGSQHSPGRTASL-NQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGP 273
+ P + ++ PG+++ L ++RP + SS S+S+ S P +GP
Sbjct: 111 SEPRSI-FEYEPGKSSILQHERPASLYQSSIDRSLERPMSSASMASDFRKRRKSEPAVGP 169
Query: 274 -----------AAPG--SAPGSQYGTMTRQISRHNSTTSSTSSGG 305
+PG PGS T+T+ + + ++ S + GG
Sbjct: 170 PRGLGDQSASRTSPGRVDLPGSS-TTLTKSFTSSSPSSPSRAKGG 213
>gi|224586849 sorbin and SH3 domain containing 2 isoform 5 [Homo
sapiens]
Length = 661
Score = 58.2 bits (139), Expect = 2e-08
Identities = 34/96 (35%), Positives = 47/96 (48%), Gaps = 8/96 (8%)
Query: 386 PPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNYI---EKVVAIYDYTKDKDDELSFME 442
P PP P Y + + N P P + +N E A+Y+YT +DEL E
Sbjct: 569 PDPPIPHSYSSDRIHSLSSNKPQR---PVFTHENIQGGGEPFQALYNYTPRNEDELELRE 625
Query: 443 GAIIYVIKKNDDGWYEGVCNRVT--GLFPGNYVESI 476
+I V++K DDGW+ G R G FPGNYV+ +
Sbjct: 626 SDVIDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL 661
Score = 51.6 bits (122), Expect = 2e-06
Identities = 21/51 (41%), Positives = 32/51 (62%)
Query: 426 AIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESI 476
A+YD+ ELSF +G +Y+++K D WYEG + G+FP +YVE +
Sbjct: 431 AVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVEKL 481
Score = 42.4 bits (98), Expect = 0.001
Identities = 25/71 (35%), Positives = 38/71 (53%), Gaps = 4/71 (5%)
Query: 413 PAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGV---CNRVTGLFP 469
P A I + +A Y++ D + ELS +G + ++K+ D WYEG NR G+FP
Sbjct: 493 PPPAQPGEIGEAIAKYNFNADTNVELSLRKGDRVILLKRVDQNWYEGKIPGTNR-QGIFP 551
Query: 470 GNYVESIMHYT 480
+YVE + T
Sbjct: 552 VSYVEVVKKNT 562
>gi|224586844 sorbin and SH3 domain containing 2 isoform 3 [Homo
sapiens]
Length = 644
Score = 58.2 bits (139), Expect = 2e-08
Identities = 34/96 (35%), Positives = 47/96 (48%), Gaps = 8/96 (8%)
Query: 386 PPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNYI---EKVVAIYDYTKDKDDELSFME 442
P PP P Y + + N P P + +N E A+Y+YT +DEL E
Sbjct: 552 PDPPIPHSYSSDRIHSLSSNKPQR---PVFTHENIQGGGEPFQALYNYTPRNEDELELRE 608
Query: 443 GAIIYVIKKNDDGWYEGVCNRVT--GLFPGNYVESI 476
+I V++K DDGW+ G R G FPGNYV+ +
Sbjct: 609 SDVIDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL 644
Score = 53.1 bits (126), Expect = 5e-07
Identities = 67/298 (22%), Positives = 101/298 (33%), Gaps = 36/298 (12%)
Query: 196 TPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSS 255
T +K + V P + N P H +T + ++HS +S + +S
Sbjct: 186 TMFKQIHMVHKPGLYN-----PPYSAQSHPAAKTQTYRPLSKSHSDNSPNAFK----DAS 236
Query: 256 SIGIPIAVPTPSPPTIGPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQ 315
S P VP P PP + P S + R++ + S Y S Q
Sbjct: 237 SPVPPPHVPPPVPP-LRPRDRSSTEKHDWDPPDRKVDTRKFRSEPRSIFEYEPGKSSILQ 295
Query: 316 FSAQPHVNGGPLYS-------QNSISIAPPPPPMPQLTPQIPLTGFVARVQENIADSPTP 368
H LY + +S A + P G + D
Sbjct: 296 -----HERPASLYQSSIDRSLERPMSSASMASDFRKRRKSEPAVG----PPRGLGDQSAS 346
Query: 369 PPPPPPDDIP--------MFDDSPPPPPPPPVDYEDEEAAVVQYNDP--YADGDPAWAPK 418
P D+P F S P P D E + D A + P+
Sbjct: 347 RTSPGRVDLPGSSTTLTKSFTSSSPSSPSRAKDRESPRSYSSTLTDMGRSAPRERRGTPE 406
Query: 419 NYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESI 476
A+YD+ ELSF +G +Y+++K D WYEG + G+FP +YVE +
Sbjct: 407 KEKLPAKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVEKL 464
Score = 47.8 bits (112), Expect = 2e-05
Identities = 81/368 (22%), Positives = 131/368 (35%), Gaps = 85/368 (23%)
Query: 156 LKAKHGNNQP-ARTGTLSRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYM 214
L H +N P A S PP PP PP+ R +T +P +
Sbjct: 220 LSKSHSDNSPNAFKDASSPVPPPHVPPPVPPLRPRDR--SSTEKHDWDPPDRKVDTRKFR 277
Query: 215 TSPARLGSQHSPGRTASL-NQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGP 273
+ P + ++ PG+++ L ++RP + SS S+S+ S P +GP
Sbjct: 278 SEPRSI-FEYEPGKSSILQHERPASLYQSSIDRSLERPMSSASMASDFRKRRKSEPAVGP 336
Query: 274 -----------AAPGSA--PGSQYGTMTRQISRHNSTTSSTSSGGYRRTP-----SVTAQ 315
+PG PGS T+T+ + +S+ SS S R +P ++T
Sbjct: 337 PRGLGDQSASRTSPGRVDLPGSST-TLTKSFT--SSSPSSPSRAKDRESPRSYSSTLTDM 393
Query: 316 FSAQPHVNGGP-------------LYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQENI 362
+ P G +Q S ++ + +I + +
Sbjct: 394 GRSAPRERRGTPEKEKLPAKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRV 453
Query: 363 ADSP-------TPPPPPPPDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYNDPYADGDPAW 415
P TPP P + PPPP P +
Sbjct: 454 GIFPISYVEKLTPPEKAQP--------ARPPPPAQPGE---------------------- 483
Query: 416 APKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGV---CNRVTGLFPGNY 472
I + +A Y++ D + ELS +G + ++K+ D WYEG NR G+FP +Y
Sbjct: 484 -----IGEAIAKYNFNADTNVELSLRKGDRVILLKRVDQNWYEGKIPGTNR-QGIFPVSY 537
Query: 473 VESIMHYT 480
VE + T
Sbjct: 538 VEVVKKNT 545
>gi|203098098 shroom family member 3 protein [Homo sapiens]
Length = 1996
Score = 58.2 bits (139), Expect = 2e-08
Identities = 66/266 (24%), Positives = 97/266 (36%), Gaps = 40/266 (15%)
Query: 169 GTLSRTNPPTQKP-PSPPMSGRGTLGRNTPYKTLEPVKPP---TVPNDYMTSPARLGSQH 224
GTL ++ P P PP++G L +T L P+ P +P+ Y + + G Q
Sbjct: 1318 GTLDHQRQASRTPCPRPPLAGTQGLVTDTRAAPLTPIGTPLPSAIPSGYCSQDGQTGRQP 1377
Query: 225 SPGRTASLNQRPRTHS-----GSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPAAPGSA 279
P T ++ R H+ G G G G G V P P P S
Sbjct: 1378 LPPYTPAMMHRSNGHTLTQPPGPRGCEGDGPEHGVEE-GTRKRVSLPQWP------PPSR 1430
Query: 280 PGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFS-AQPHVNGGPLYSQNSISIA-- 336
+ + +S + Y++ S+ + S + P G + IS+
Sbjct: 1431 AKWAHAAREDSLPEESSAPDFANLKHYQKQQSLPSLCSTSDPDTPLGAPSTPGRISLRIS 1490
Query: 337 -----PPPPPMPQLTPQIPLTGFVARVQENIADSPT------PPPPPPPDDIPMF--DDS 383
PPP ++ FV SPT PPPPPP + P++ DD
Sbjct: 1491 ESVLRDSPPPHEDYEDEV----FVRDPHPKATSSPTFEPLPPPPPPPPSQETPVYSMDDF 1546
Query: 384 PPPPP----PPPVDYEDEEAAVVQYN 405
PPPPP +D ED E +N
Sbjct: 1547 PPPPPHTVCEAQLDSEDPEGPRPSFN 1572
>gi|10947118 sorbin and SH3 domain containing 2 isoform 2 [Homo
sapiens]
Length = 1100
Score = 58.2 bits (139), Expect = 2e-08
Identities = 34/96 (35%), Positives = 47/96 (48%), Gaps = 8/96 (8%)
Query: 386 PPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNYI---EKVVAIYDYTKDKDDELSFME 442
P PP P Y + + N P P + +N E A+Y+YT +DEL E
Sbjct: 1008 PDPPIPHSYSSDRIHSLSSNKPQR---PVFTHENIQGGGEPFQALYNYTPRNEDELELRE 1064
Query: 443 GAIIYVIKKNDDGWYEGVCNRVT--GLFPGNYVESI 476
+I V++K DDGW+ G R G FPGNYV+ +
Sbjct: 1065 SDVIDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL 1100
Score = 51.6 bits (122), Expect = 2e-06
Identities = 21/51 (41%), Positives = 32/51 (62%)
Query: 426 AIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESI 476
A+YD+ ELSF +G +Y+++K D WYEG + G+FP +YVE +
Sbjct: 870 AVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVEKL 920
Score = 42.4 bits (98), Expect = 0.001
Identities = 25/71 (35%), Positives = 38/71 (53%), Gaps = 4/71 (5%)
Query: 413 PAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGV---CNRVTGLFP 469
P A I + +A Y++ D + ELS +G + ++K+ D WYEG NR G+FP
Sbjct: 932 PPPAQPGEIGEAIAKYNFNADTNVELSLRKGDRVILLKRVDQNWYEGKIPGTNR-QGIFP 990
Query: 470 GNYVESIMHYT 480
+YVE + T
Sbjct: 991 VSYVEVVKKNT 1001
Score = 33.5 bits (75), Expect = 0.44
Identities = 38/165 (23%), Positives = 64/165 (38%), Gaps = 19/165 (11%)
Query: 156 LKAKHGNNQPARTGTLSRTNPPTQKPPS-PPMSGRGTLGRNTPYKTLEPVKPPTVPNDYM 214
L H +N P S PP PP PP+ R +T +P +
Sbjct: 149 LSKSHSDNSPNAFKDASSPVPPPHVPPPVPPLRPRDR--SSTEKHDWDPPDRKVDTRKFR 206
Query: 215 TSPARLGSQHSPGRTASL-NQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGP 273
+ P + ++ PG+++ L ++RP + SS S+S+ S P +GP
Sbjct: 207 SEPRSI-FEYEPGKSSILQHERPASLYQSSIDRSLERPMSSASMASDFRKRRKSEPAVGP 265
Query: 274 -----------AAPG--SAPGSQYGTMTRQISRHNSTTSSTSSGG 305
+PG PGS T+T+ + + ++ S + GG
Sbjct: 266 PRGLGDQSASRTSPGRVDLPGSS-TTLTKSFTSSSPSSPSRAKGG 309
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.130 0.387
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,158,237
Number of Sequences: 37866
Number of extensions: 1733239
Number of successful extensions: 32159
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 640
Number of HSP's successfully gapped in prelim test: 1164
Number of HSP's that attempted gapping in prelim test: 12382
Number of HSP's gapped (non-prelim): 10394
length of query: 481
length of database: 18,247,518
effective HSP length: 106
effective length of query: 375
effective length of database: 14,233,722
effective search space: 5337645750
effective search space used: 5337645750
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.