Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 61743944

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|61743944 abl-interactor 1 isoform b [Homo sapiens]
         (481 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|61743944 abl-interactor 1 isoform b [Homo sapiens]                 988   0.0  
gi|61743942 abl-interactor 1 isoform a [Homo sapiens]                 973   0.0  
gi|61743948 abl-interactor 1 isoform d [Homo sapiens]                 971   0.0  
gi|61743946 abl-interactor 1 isoform c [Homo sapiens]                 905   0.0  
gi|109689723 abl interactor 2 [Homo sapiens]                          704   0.0  
gi|7705981 NESH protein isoform 1 [Homo sapiens]                      271   1e-72
gi|206597502 NESH protein isoform 2 [Homo sapiens]                    261   8e-70
gi|194294523 intersectin 2 isoform 3 [Homo sapiens]                    65   1e-10
gi|194294521 intersectin 2 isoform 1 [Homo sapiens]                    65   1e-10
gi|194294525 intersectin 2 isoform 2 [Homo sapiens]                    65   1e-10
gi|55741677 SET domain containing 1A [Homo sapiens]                    63   7e-10
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]                 62   9e-10
gi|46094081 development and differentiation enhancing factor 1 [...    62   2e-09
gi|116284392 mucin 2 precursor [Homo sapiens]                          61   2e-09
gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]                61   3e-09
gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]                61   3e-09
gi|224586851 sorbin and SH3 domain containing 2 isoform 6 [Homo ...    60   4e-09
gi|224586846 sorbin and SH3 domain containing 2 isoform 4 [Homo ...    60   4e-09
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    60   4e-09
gi|51988887 SH3 domain containing ring finger 1 [Homo sapiens]         60   6e-09
gi|167234422 hematopoietic cell-specific Lyn substrate 1 [Homo s...    60   6e-09
gi|55956916 myosin IE [Homo sapiens]                                   59   7e-09
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    59   1e-08
gi|150417989 cyclin K isoform 1 [Homo sapiens]                         59   1e-08
gi|224586855 sorbin and SH3 domain containing 2 isoform 8 [Homo ...    58   2e-08
gi|224586853 sorbin and SH3 domain containing 2 isoform 7 [Homo ...    58   2e-08
gi|224586849 sorbin and SH3 domain containing 2 isoform 5 [Homo ...    58   2e-08
gi|224586844 sorbin and SH3 domain containing 2 isoform 3 [Homo ...    58   2e-08
gi|203098098 shroom family member 3 protein [Homo sapiens]             58   2e-08
gi|10947118 sorbin and SH3 domain containing 2 isoform 2 [Homo s...    58   2e-08

>gi|61743944 abl-interactor 1 isoform b [Homo sapiens]
          Length = 481

 Score =  988 bits (2554), Expect = 0.0
 Identities = 481/481 (100%), Positives = 481/481 (100%)

Query: 1   MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS 60
           MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS
Sbjct: 1   MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS 60

Query: 61  VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR 120
           VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR
Sbjct: 61  VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR 120

Query: 121 THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQK 180
           THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQK
Sbjct: 121 THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQK 180

Query: 181 PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHS 240
           PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHS
Sbjct: 181 PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHS 240

Query: 241 GSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPAAPGSAPGSQYGTMTRQISRHNSTTSS 300
           GSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPAAPGSAPGSQYGTMTRQISRHNSTTSS
Sbjct: 241 GSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPAAPGSAPGSQYGTMTRQISRHNSTTSS 300

Query: 301 TSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQE 360
           TSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQE
Sbjct: 301 TSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQE 360

Query: 361 NIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNY 420
           NIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNY
Sbjct: 361 NIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNY 420

Query: 421 IEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESIMHYT 480
           IEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESIMHYT
Sbjct: 421 IEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESIMHYT 480

Query: 481 D 481
           D
Sbjct: 481 D 481


>gi|61743942 abl-interactor 1 isoform a [Homo sapiens]
          Length = 508

 Score =  973 bits (2516), Expect = 0.0
 Identities = 481/508 (94%), Positives = 481/508 (94%), Gaps = 27/508 (5%)

Query: 1   MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS 60
           MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS
Sbjct: 1   MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS 60

Query: 61  VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR 120
           VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR
Sbjct: 61  VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR 120

Query: 121 THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQK 180
           THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQK
Sbjct: 121 THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQK 180

Query: 181 PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHS 240
           PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHS
Sbjct: 181 PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHS 240

Query: 241 GSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGP--------------------------- 273
           GSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGP                           
Sbjct: 241 GSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENISVPPPSGAPPAPPLAPLLPVSTVI 300

Query: 274 AAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSI 333
           AAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSI
Sbjct: 301 AAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSI 360

Query: 334 SIAPPPPPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVD 393
           SIAPPPPPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVD
Sbjct: 361 SIAPPPPPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVD 420

Query: 394 YEDEEAAVVQYNDPYADGDPAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKND 453
           YEDEEAAVVQYNDPYADGDPAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKND
Sbjct: 421 YEDEEAAVVQYNDPYADGDPAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKND 480

Query: 454 DGWYEGVCNRVTGLFPGNYVESIMHYTD 481
           DGWYEGVCNRVTGLFPGNYVESIMHYTD
Sbjct: 481 DGWYEGVCNRVTGLFPGNYVESIMHYTD 508


>gi|61743948 abl-interactor 1 isoform d [Homo sapiens]
          Length = 476

 Score =  971 bits (2509), Expect = 0.0
 Identities = 476/481 (98%), Positives = 476/481 (98%), Gaps = 5/481 (1%)

Query: 1   MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS 60
           MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS
Sbjct: 1   MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS 60

Query: 61  VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR 120
           VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR
Sbjct: 61  VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR 120

Query: 121 THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQK 180
           THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVK     HGNNQPARTGTLSRTNPPTQK
Sbjct: 121 THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVK-----HGNNQPARTGTLSRTNPPTQK 175

Query: 181 PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHS 240
           PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHS
Sbjct: 176 PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHS 235

Query: 241 GSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPAAPGSAPGSQYGTMTRQISRHNSTTSS 300
           GSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPAAPGSAPGSQYGTMTRQISRHNSTTSS
Sbjct: 236 GSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPAAPGSAPGSQYGTMTRQISRHNSTTSS 295

Query: 301 TSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQE 360
           TSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQE
Sbjct: 296 TSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQE 355

Query: 361 NIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNY 420
           NIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNY
Sbjct: 356 NIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNY 415

Query: 421 IEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESIMHYT 480
           IEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESIMHYT
Sbjct: 416 IEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESIMHYT 475

Query: 481 D 481
           D
Sbjct: 476 D 476


>gi|61743946 abl-interactor 1 isoform c [Homo sapiens]
          Length = 452

 Score =  905 bits (2339), Expect = 0.0
 Identities = 448/481 (93%), Positives = 450/481 (93%), Gaps = 29/481 (6%)

Query: 1   MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS 60
           MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS
Sbjct: 1   MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS 60

Query: 61  VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR 120
           VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR
Sbjct: 61  VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR 120

Query: 121 THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQK 180
           THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQK
Sbjct: 121 THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQK 180

Query: 181 PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHS 240
           PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHS
Sbjct: 181 PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHS 240

Query: 241 GSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPAAPGSAPGSQYGTMTRQISRHNSTTSS 300
           GSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPAAPGSAPGSQYGTMTRQISRHNSTTSS
Sbjct: 241 GSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPAAPGSAPGSQYGTMTRQISRHNSTTSS 300

Query: 301 TSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQE 360
           TSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSI+ +P P                     
Sbjct: 301 TSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSIADSPTP--------------------- 339

Query: 361 NIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNY 420
                   PPPPPPDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNY
Sbjct: 340 --------PPPPPPDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNY 391

Query: 421 IEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESIMHYT 480
           IEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESIMHYT
Sbjct: 392 IEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESIMHYT 451

Query: 481 D 481
           D
Sbjct: 452 D 452


>gi|109689723 abl interactor 2 [Homo sapiens]
          Length = 475

 Score =  704 bits (1816), Expect = 0.0
 Identities = 358/491 (72%), Positives = 406/491 (82%), Gaps = 26/491 (5%)

Query: 1   MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS 60
           MAELQMLLEEEIP G+RAL +SY NL RVADYCENNYIQ+ DK++ALEETKAYTTQSLAS
Sbjct: 1   MAELQMLLEEEIPGGRRALFDSYTNLERVADYCENNYIQSADKQRALEETKAYTTQSLAS 60

Query: 61  VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR 120
           VAY IN LANNVLQ+LDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR
Sbjct: 61  VAYLINTLANNVLQMLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR 120

Query: 121 THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQK 180
           THKIIAPAN+ERPVRYIRKPIDYT+LDD+GHGVK       + Q  + G L RT PPTQK
Sbjct: 121 THKIIAPANLERPVRYIRKPIDYTILDDIGHGVK------VSTQNMKMGGLPRTTPPTQK 174

Query: 181 PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPAR--LGSQHSPGRTASLNQRPRT 238
           PPSPPMSG+GTLGR++PY+TLEPV+PP VPNDY+ SP R    SQ SP RTAS+NQR RT
Sbjct: 175 PPSPPMSGKGTLGRHSPYRTLEPVRPPVVPNDYVPSPTRNMAPSQQSPVRTASVNQRNRT 234

Query: 239 H--SGSSGG------SGSRENSGSSSIGIPIAVPTPSPPTIGPAAPGSAPGSQYGTMTRQ 290
           +  SGSSGG      S SRENSGS S+G+PIAVPTPSPP++ P  P      Q+ +M R 
Sbjct: 235 YSSSGSSGGSHPSSRSSSRENSGSGSVGVPIAVPTPSPPSVFPGHP-----VQFYSMNRP 289

Query: 291 ISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQIP 350
            SRH   T    S  YRR PS+T+Q S Q  +NGGP YSQN +S+APPPP + Q+TPQ+P
Sbjct: 290 ASRHTPPTIG-GSLPYRRPPSITSQTSLQNQMNGGPFYSQNPVSLAPPPPSILQVTPQLP 348

Query: 351 LTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYNDPYAD 410
           L GFVARVQENI+D+   PPPPPP + P+FD+SPPPPPPP  DYE+EEAAVV+Y+DPYA+
Sbjct: 349 LMGFVARVQENISDT---PPPPPPVEEPVFDESPPPPPPPE-DYEEEEAAVVEYSDPYAE 404

Query: 411 GDPAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPG 470
            DP WAP++Y+EKVVAIYDYTKDK+DELSF EGAIIYVIKKNDDGWYEGV N VTGLFPG
Sbjct: 405 EDPPWAPRSYLEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPG 464

Query: 471 NYVESIMHYTD 481
           NYVESIMHY++
Sbjct: 465 NYVESIMHYSE 475


>gi|7705981 NESH protein isoform 1 [Homo sapiens]
          Length = 366

 Score =  271 bits (692), Expect = 1e-72
 Identities = 185/474 (39%), Positives = 244/474 (51%), Gaps = 111/474 (23%)

Query: 1   MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS 60
           MAELQ L E EIP+G+ AL  ++  L RVADYCE+NY+QATDKRKALEET A+TTQ+LAS
Sbjct: 1   MAELQQLQEFEIPTGREALRGNHSALLRVADYCEDNYVQATDKRKALEETMAFTTQALAS 60

Query: 61  VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR 120
           VAYQ+  LA + L++LD+Q + LR++E+ ++ + Q V++H EKVARREIG L T +    
Sbjct: 61  VAYQVGNLAGHTLRMLDLQGAALRQVEARVSTLGQMVNMHMEKVARREIGTLATVQRLPP 120

Query: 121 THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQK 180
             K+IAP N+     Y R+P+++  LDD+GHG+K L     + Q +RTGTLSR    + K
Sbjct: 121 GQKVIAPENLPPLTPYCRRPLNFGCLDDIGHGIKDL-----STQLSRTGTLSR---KSIK 172

Query: 181 PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHS 240
            P+ P S   TLGR  P +  EPV  P VP+       RL +  S    AS        +
Sbjct: 173 APATPAS--ATLGR--PPRIPEPVHLPVVPD------GRLSAASSASSLAS--------A 214

Query: 241 GSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPAAPGSAPGSQYGTMTRQISRHNSTTSS 300
           GS+ G G                PTP     G AAP + P                    
Sbjct: 215 GSAEGVG--------------GAPTPK----GQAAPPAPP-------------------L 237

Query: 301 TSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQE 360
            SS      P+    F   P +            ++PPPP       ++PL         
Sbjct: 238 PSSLDPPPPPAAVEVFQRPPTLE----------ELSPPPP-----DEELPL--------- 273

Query: 361 NIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNY 420
                P   PPPPP D    D+   PPPPP                 +   +P+W P +Y
Sbjct: 274 -----PLDLPPPPPLD---GDELGLPPPPP----------------GFGPDEPSWVPASY 309

Query: 421 IEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVE 474
           +EKVV +Y YT  KD+ELSF EG +I V ++  DGW EGV +  TG FPGNYVE
Sbjct: 310 LEKVVTLYPYTSQKDNELSFSEGTVICVTRRYSDGWCEGVSSEGTGFFPGNYVE 363


>gi|206597502 NESH protein isoform 2 [Homo sapiens]
          Length = 360

 Score =  261 bits (668), Expect = 8e-70
 Identities = 184/474 (38%), Positives = 241/474 (50%), Gaps = 117/474 (24%)

Query: 1   MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS 60
           MAELQ L E EIP+G+ AL  ++  L RVADYCE+NY+QATDKRKALEET A+TTQ+LAS
Sbjct: 1   MAELQQLQEFEIPTGREALRGNHSALLRVADYCEDNYVQATDKRKALEETMAFTTQALAS 60

Query: 61  VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR 120
           VAYQ+  LA + L++LD+Q + LR++E      ++ V++H EKVARREIG L T +    
Sbjct: 61  VAYQVGNLAGHTLRMLDLQGAALRQVE------ARMVNMHMEKVARREIGTLATVQRLPP 114

Query: 121 THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQK 180
             K+IAP N+     Y R+P+++  LDD+GHG+K L     + Q +RTGTLSR    + K
Sbjct: 115 GQKVIAPENLPPLTPYCRRPLNFGCLDDIGHGIKDL-----STQLSRTGTLSR---KSIK 166

Query: 181 PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHS 240
            P+ P S   TLGR  P +  EPV  P VP+       RL +  S    AS        +
Sbjct: 167 APATPAS--ATLGR--PPRIPEPVHLPVVPD------GRLSAASSASSLAS--------A 208

Query: 241 GSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPAAPGSAPGSQYGTMTRQISRHNSTTSS 300
           GS+ G G                PTP     G AAP + P                    
Sbjct: 209 GSAEGVG--------------GAPTPK----GQAAPPAPP-------------------L 231

Query: 301 TSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQE 360
            SS      P+    F   P +            ++PPPP       ++PL         
Sbjct: 232 PSSLDPPPPPAAVEVFQRPPTLE----------ELSPPPP-----DEELPL--------- 267

Query: 361 NIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNY 420
                P   PPPPP D    D+   PPPPP                 +   +P+W P +Y
Sbjct: 268 -----PLDLPPPPPLD---GDELGLPPPPP----------------GFGPDEPSWVPASY 303

Query: 421 IEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVE 474
           +EKVV +Y YT  KD+ELSF EG +I V ++  DGW EGV +  TG FPGNYVE
Sbjct: 304 LEKVVTLYPYTSQKDNELSFSEGTVICVTRRYSDGWCEGVSSEGTGFFPGNYVE 357


>gi|194294523 intersectin 2 isoform 3 [Homo sapiens]
          Length = 1670

 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 30/62 (48%), Positives = 44/62 (70%), Gaps = 3/62 (4%)

Query: 413  PAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNY 472
            PA+ P   + +V+A+YDY  + +DELSF +G +I V+ K+D  W++G  N VTGLFP NY
Sbjct: 1097 PAFHP---VCQVIAMYDYAANNEDELSFSKGQLINVMNKDDPDWWQGEINGVTGLFPSNY 1153

Query: 473  VE 474
            V+
Sbjct: 1154 VK 1155



 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 28/87 (32%), Positives = 42/87 (48%), Gaps = 6/87 (6%)

Query: 388  PPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIY 447
            P   V  E+ EA     N       P  A  +  E+ +A+Y Y+  +  +L+F EG  I 
Sbjct: 928  PGSEVKREEPEALYAAVNKK-----PTSAAYSVGEEYIALYPYSSVEPGDLTFTEGEEIL 982

Query: 448  VIKKNDDGWYEGVCNRVTGLFPGNYVE 474
            V +K D  W+ G     +G+FP NYV+
Sbjct: 983  VTQK-DGEWWTGSIGDRSGIFPSNYVK 1008



 Score = 36.6 bits (83), Expect = 0.052
 Identities = 21/53 (39%), Positives = 27/53 (50%), Gaps = 2/53 (3%)

Query: 426 AIYDYTKDKDDELSFMEGAIIYVIKK--NDDGWYEGVCNRVTGLFPGNYVESI 476
           A+Y +     DE+SF  G II V +K   + GW  G      G FP NYVE +
Sbjct: 737 ALYPFEARNHDEMSFNSGDIIQVDEKTVGEPGWLYGSFQGNFGWFPCNYVEKM 789



 Score = 35.0 bits (79), Expect = 0.15
 Identities = 16/50 (32%), Positives = 26/50 (52%), Gaps = 5/50 (10%)

Query: 430  YTKDKDDELSFMEGAIIYVIKKNDDGWYEGVC-----NRVTGLFPGNYVE 474
            Y     ++LS   G +I ++KKN  GW++G        R  G FP ++V+
Sbjct: 1037 YVASGSEQLSLAPGQLILILKKNTSGWWQGELQARGKKRQKGWFPASHVK 1086



 Score = 33.9 bits (76), Expect = 0.34
 Identities = 18/54 (33%), Positives = 32/54 (59%), Gaps = 1/54 (1%)

Query: 423 KVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESI 476
           K  A+  +T  KD+ L+F +  II V+++ ++ W+ G  +   G FP +YV+ I
Sbjct: 875 KAQALCSWTAKKDNHLNFSKHDIITVLEQQENWWF-GEVHGGRGWFPKSYVKII 927


>gi|194294521 intersectin 2 isoform 1 [Homo sapiens]
          Length = 1697

 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 30/62 (48%), Positives = 44/62 (70%), Gaps = 3/62 (4%)

Query: 413  PAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNY 472
            PA+ P   + +V+A+YDY  + +DELSF +G +I V+ K+D  W++G  N VTGLFP NY
Sbjct: 1124 PAFHP---VCQVIAMYDYAANNEDELSFSKGQLINVMNKDDPDWWQGEINGVTGLFPSNY 1180

Query: 473  VE 474
            V+
Sbjct: 1181 VK 1182



 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 28/87 (32%), Positives = 42/87 (48%), Gaps = 6/87 (6%)

Query: 388  PPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIY 447
            P   V  E+ EA     N       P  A  +  E+ +A+Y Y+  +  +L+F EG  I 
Sbjct: 955  PGSEVKREEPEALYAAVNKK-----PTSAAYSVGEEYIALYPYSSVEPGDLTFTEGEEIL 1009

Query: 448  VIKKNDDGWYEGVCNRVTGLFPGNYVE 474
            V +K D  W+ G     +G+FP NYV+
Sbjct: 1010 VTQK-DGEWWTGSIGDRSGIFPSNYVK 1035



 Score = 36.6 bits (83), Expect = 0.052
 Identities = 21/53 (39%), Positives = 27/53 (50%), Gaps = 2/53 (3%)

Query: 426 AIYDYTKDKDDELSFMEGAIIYVIKK--NDDGWYEGVCNRVTGLFPGNYVESI 476
           A+Y +     DE+SF  G II V +K   + GW  G      G FP NYVE +
Sbjct: 764 ALYPFEARNHDEMSFNSGDIIQVDEKTVGEPGWLYGSFQGNFGWFPCNYVEKM 816



 Score = 35.0 bits (79), Expect = 0.15
 Identities = 16/50 (32%), Positives = 26/50 (52%), Gaps = 5/50 (10%)

Query: 430  YTKDKDDELSFMEGAIIYVIKKNDDGWYEGVC-----NRVTGLFPGNYVE 474
            Y     ++LS   G +I ++KKN  GW++G        R  G FP ++V+
Sbjct: 1064 YVASGSEQLSLAPGQLILILKKNTSGWWQGELQARGKKRQKGWFPASHVK 1113



 Score = 33.9 bits (76), Expect = 0.34
 Identities = 18/54 (33%), Positives = 32/54 (59%), Gaps = 1/54 (1%)

Query: 423 KVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESI 476
           K  A+  +T  KD+ L+F +  II V+++ ++ W+ G  +   G FP +YV+ I
Sbjct: 902 KAQALCSWTAKKDNHLNFSKHDIITVLEQQENWWF-GEVHGGRGWFPKSYVKII 954


>gi|194294525 intersectin 2 isoform 2 [Homo sapiens]
          Length = 1249

 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 30/62 (48%), Positives = 44/62 (70%), Gaps = 3/62 (4%)

Query: 413  PAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNY 472
            PA+ P   + +V+A+YDY  + +DELSF +G +I V+ K+D  W++G  N VTGLFP NY
Sbjct: 1124 PAFHP---VCQVIAMYDYAANNEDELSFSKGQLINVMNKDDPDWWQGEINGVTGLFPSNY 1180

Query: 473  VE 474
            V+
Sbjct: 1181 VK 1182



 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 28/87 (32%), Positives = 42/87 (48%), Gaps = 6/87 (6%)

Query: 388  PPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIY 447
            P   V  E+ EA     N       P  A  +  E+ +A+Y Y+  +  +L+F EG  I 
Sbjct: 955  PGSEVKREEPEALYAAVNKK-----PTSAAYSVGEEYIALYPYSSVEPGDLTFTEGEEIL 1009

Query: 448  VIKKNDDGWYEGVCNRVTGLFPGNYVE 474
            V +K D  W+ G     +G+FP NYV+
Sbjct: 1010 VTQK-DGEWWTGSIGDRSGIFPSNYVK 1035



 Score = 36.6 bits (83), Expect = 0.052
 Identities = 21/53 (39%), Positives = 27/53 (50%), Gaps = 2/53 (3%)

Query: 426 AIYDYTKDKDDELSFMEGAIIYVIKK--NDDGWYEGVCNRVTGLFPGNYVESI 476
           A+Y +     DE+SF  G II V +K   + GW  G      G FP NYVE +
Sbjct: 764 ALYPFEARNHDEMSFNSGDIIQVDEKTVGEPGWLYGSFQGNFGWFPCNYVEKM 816



 Score = 35.0 bits (79), Expect = 0.15
 Identities = 16/50 (32%), Positives = 26/50 (52%), Gaps = 5/50 (10%)

Query: 430  YTKDKDDELSFMEGAIIYVIKKNDDGWYEGVC-----NRVTGLFPGNYVE 474
            Y     ++LS   G +I ++KKN  GW++G        R  G FP ++V+
Sbjct: 1064 YVASGSEQLSLAPGQLILILKKNTSGWWQGELQARGKKRQKGWFPASHVK 1113



 Score = 33.9 bits (76), Expect = 0.34
 Identities = 18/54 (33%), Positives = 32/54 (59%), Gaps = 1/54 (1%)

Query: 423 KVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESI 476
           K  A+  +T  KD+ L+F +  II V+++ ++ W+ G  +   G FP +YV+ I
Sbjct: 902 KAQALCSWTAKKDNHLNFSKHDIITVLEQQENWWF-GEVHGGRGWFPKSYVKII 954


>gi|55741677 SET domain containing 1A [Homo sapiens]
          Length = 1707

 Score = 62.8 bits (151), Expect = 7e-10
 Identities = 70/271 (25%), Positives = 87/271 (32%), Gaps = 67/271 (24%)

Query: 164 QPARTGTLSRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGS- 222
           +P+R        P ++ PP  P    G  G   P    E V+    P     SPAR GS 
Sbjct: 416 EPSRPTDQDYRPPASEAPPPEPPEPGGGGGGGGPSPEREEVRTSPRP----ASPARSGSP 471

Query: 223 ------------QHSP--GRTASLNQRPRTHSGSSGGSGSRENSGSSSI--GIPIAVPTP 266
                       QHS    R   L +  R+           E   SS +          P
Sbjct: 472 APETTNESVPFAQHSSLDSRIEMLLKEQRSKFSFLASDTEEEEENSSMVLGARDTGSEVP 531

Query: 267 SPPTIGPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGP 326
           S    GP  P  AP +             + T S   G  R +P    Q  A P  +G  
Sbjct: 532 SGSGHGPCTPPPAPANFEDV---------APTGSGEPGATRESPKANGQNQASPCSSGDD 582

Query: 327 L-YSQNSISIAPPPPPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPP----------- 374
           +  S +    +PPP P P   P  P               P PPPPPPP           
Sbjct: 583 MEISDDDRGGSPPPAPTPPQQPPPP---------------PPPPPPPPPYLASLPLGYPP 627

Query: 375 ----------DDIPMFDDSPPPPPPPPVDYE 395
                      D P   + PPPPPPPP  Y+
Sbjct: 628 HQPAYLLPPRPDGPPPPEYPPPPPPPPHIYD 658



 Score = 39.7 bits (91), Expect = 0.006
 Identities = 63/240 (26%), Positives = 85/240 (35%), Gaps = 46/240 (19%)

Query: 161 GNNQPARTGTL---SRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSP 217
           GN  P    T    SR + P+      P S +GT     PY T     P +  + Y +S 
Sbjct: 238 GNGTPCSQDTSFSSSRQDTPSSFGQFTPQSSQGT-----PY-TSRGSTPYSQDSAYSSS- 290

Query: 218 ARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPAAPG 277
                      T S + +PR    S   + SR +  +SS     +  T    T    A  
Sbjct: 291 -----------TTSTSFKPRRSENSYQDAFSRRHFSASSASTTAS--TAIAATTAATASS 337

Query: 278 SAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAP 337
           SA  S        +S  +S++SS+SS  +R   S  A + A          S N      
Sbjct: 338 SASSSS-------LSSSSSSSSSSSSSQFR---SSDANYPAYYE-------SWNRYQRHT 380

Query: 338 PPPPMPQLTPQIPLTGFVARVQENIADSPT---PPPPPPPDDI---PMFDDSPPPPPPPP 391
             PP      + P   F     E    S T   PP P  P D    P   ++PPP PP P
Sbjct: 381 SYPPRRATREEPPGAPFAENTAERFPPSYTSYLPPEPSRPTDQDYRPPASEAPPPEPPEP 440



 Score = 37.0 bits (84), Expect = 0.040
 Identities = 34/127 (26%), Positives = 51/127 (40%), Gaps = 12/127 (9%)

Query: 281  GSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPP 340
            G    T   + S  +S++SS+SS     + S +++ S++         +  S S  PPP 
Sbjct: 1025 GENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAALPSAS--PPPR 1082

Query: 341  PMPQLTP---QIPLTGFVARV-------QENIADSPTPPPPPPPDDIPMFDDSPPPPPPP 390
             +P  TP   ++P+   VA         QE     P  P    P   P+    PP  PP 
Sbjct: 1083 EVPVPTPAPVEVPVPERVAGSPVTPLPEQEASPARPAGPTEESPPSAPLRPPEPPAGPPA 1142

Query: 391  PVDYEDE 397
            P    DE
Sbjct: 1143 PAPRPDE 1149



 Score = 34.3 bits (77), Expect = 0.26
 Identities = 47/176 (26%), Positives = 59/176 (33%), Gaps = 33/176 (18%)

Query: 225  SPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGI-----PIAVPTPSPPTIGPAAPGSA 279
            S   ++S +    + S SS  S S  +S SSS        P A+P+ SPP      P  A
Sbjct: 1031 SDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAALPSASPPPREVPVPTPA 1090

Query: 280  PGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPP 339
            P                        G   TP    +  A P    GP  ++ S   AP  
Sbjct: 1091 P--------------VEVPVPERVAGSPVTP--LPEQEASPARPAGP--TEESPPSAPLR 1132

Query: 340  PPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPD-----DIPMFDDSPPPPPPP 390
            PP P   P  P     A   +    SP P  PPP            +  P P PPP
Sbjct: 1133 PPEPPAGPPAP-----APRPDERPSSPIPLLPPPKKRRKTVSFSAIEVVPAPEPPP 1183


>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
          Length = 639

 Score = 62.4 bits (150), Expect = 9e-10
 Identities = 63/228 (27%), Positives = 80/228 (35%), Gaps = 51/228 (22%)

Query: 176 PPTQKPPSPPMS-GRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQ 234
           PP  +PP PPM+ G    G + P        PP   + Y+            G T   + 
Sbjct: 422 PPWMQPPPPPMNQGPHPPGHHGP--------PPM--DQYL------------GSTPVGSG 459

Query: 235 RPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPAAPGSA---------PGSQYG 285
             R H G   G       G      P     P PP  GP  P            P S   
Sbjct: 460 VYRLHQGK--GMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSM 517

Query: 286 TMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQL 345
             +  +    +TT++T+S G    P    Q +A     G P    N   +  PP   P L
Sbjct: 518 ASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPL 577

Query: 346 TPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVD 393
            P                 +P PPPPPPP    M   +PPPPPPPP+D
Sbjct: 578 PP----------------GAPPPPPPPPPGSAGMMY-APPPPPPPPMD 608



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 58/245 (23%), Positives = 80/245 (32%), Gaps = 64/245 (26%)

Query: 140 PID-YTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQKPPSPPMSGRGTLGRNTPY 198
           P+D Y     VG GV  L    G   P   G +    PP    P PP S     G   P+
Sbjct: 446 PMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPS-----GPLPPW 500

Query: 199 -KTLEPVKPPTVPNDYMTSPARLGSQH------SPGRTASLNQRPRTHSGSSGGSGSREN 251
            +  +   PP  P+  M S   L  Q       +   T S+    +  + ++   G+ + 
Sbjct: 501 QQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQM 560

Query: 252 SGS-SSIGIPIAVPTPSPPTIGPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTP 310
            G+ + + +P  V  P PP   P  P   PGS                            
Sbjct: 561 QGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGS---------------------------- 592

Query: 311 SVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQ--IPLTGFVARVQENIADSPTP 368
                         G +Y       APPPPP P + P   + + G            P P
Sbjct: 593 -------------AGMMY-------APPPPPPPPMDPSNFVTMMGMGVAGMPPFGMPPAP 632

Query: 369 PPPPP 373
           PPPPP
Sbjct: 633 PPPPP 637



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 40/140 (28%), Positives = 46/140 (32%), Gaps = 33/140 (23%)

Query: 272 GPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQN 331
           GP  PG  P S    +      H       +  G    P         P +N GP     
Sbjct: 386 GPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNG----PPPPWMQPPPPPMNQGP----- 436

Query: 332 SISIAPP----PPPMPQLTPQIPLTGFVARVQENIADSPTPP------PPPPPDDIPMFD 381
                PP    PPPM Q     P+   V R+ +     P PP      PPPPP   P   
Sbjct: 437 ----HPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPP 492

Query: 382 DSPP----------PPPPPP 391
            S P          PPPPPP
Sbjct: 493 PSGPLPPWQQQQQQPPPPPP 512



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 58/227 (25%), Positives = 70/227 (30%), Gaps = 42/227 (18%)

Query: 165 PARTGTLSRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGS-Q 223
           PA T   S   P       PP S   T     P+    P +       +   P   G   
Sbjct: 335 PATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGP 394

Query: 224 HS-PGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPAAPGS---A 279
           HS P    SL       +G  GG   + N        P   P P P   GP  PG     
Sbjct: 395 HSFPHPLPSL-------TGGHGGHPMQHNPNGPPP--PWMQPPPPPMNQGPHPPGHHGPP 445

Query: 280 PGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPP 339
           P  QY   T              SG YR                G  +     + + PPP
Sbjct: 446 PMDQYLGST-----------PVGSGVYRLH-------------QGKGMMPPPPMGMMPPP 481

Query: 340 PPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPP 386
           PP P   P  P +G +   Q+        PPPPPP    M   +P P
Sbjct: 482 PPPPSGQPPPPPSGPLPPWQQ----QQQQPPPPPPPSSSMASSTPLP 524



 Score = 31.6 bits (70), Expect = 1.7
 Identities = 39/140 (27%), Positives = 49/140 (35%), Gaps = 32/140 (22%)

Query: 260 PIAVPTPSPPTIGPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQ 319
           P   P  S P   PAAP + P       T Q       +  + S  Y             
Sbjct: 335 PATTPLASAPR--PAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYH------GMHGGG 386

Query: 320 PHVNGGPLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQENIADSPTPP---PPPPPDD 376
           P   GGP    +S      P P+P LT      G      ++  + P PP   PPPPP  
Sbjct: 387 P---GGPGGGPHSF-----PHPLPSLTG-----GHGGHPMQHNPNGPPPPWMQPPPPP-- 431

Query: 377 IPMFDDSPPPPP---PPPVD 393
               +  P PP    PPP+D
Sbjct: 432 ---MNQGPHPPGHHGPPPMD 448


>gi|46094081 development and differentiation enhancing factor 1 [Homo
            sapiens]
          Length = 1129

 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 95/359 (26%), Positives = 134/359 (37%), Gaps = 65/359 (18%)

Query: 168  TGTLSRTNPPTQKPPSPPMS-GRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSP 226
            T T S T+P T+ PP PP + G+G  G   P  TL P+   T       S  R      P
Sbjct: 778  TSTDSPTSPTTEAPPLPPRNAGKGPTG---PPSTL-PLSTQTSSGSSTLSKKR-PPPPPP 832

Query: 227  G--RTASLNQRPRTHS---------GSSGGSGSRENSGSSSIGIPIAVPTPSPPT-IGPA 274
            G  RT S    P  H          G+ GG  S   + +   G+     T S  T +GP 
Sbjct: 833  GHKRTLSDPPSPLPHGPPNKGAVPWGNDGGPSSSSKTTNKFEGLSQQSSTSSAKTALGPR 892

Query: 275  APGSAPGSQYGTMTRQISRHNSTT-------SSTSSGGYRRTPS-----VTAQFSAQPHV 322
                 P       T  +S   +T        SS  +   ++ P         + + +P +
Sbjct: 893  VLPKLPQKVALRKTDHLSLDKATIPPEIFQKSSQLAELPQKPPPGDLPPKPTELAPKPQI 952

Query: 323  NG--------------GPLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQENIADSPTP 368
                            G L  +  +S  PP P M  L P+  L   +A+ Q         
Sbjct: 953  GDLPPKPGELPPKPQLGDLPPKPQLSDLPPKPQMKDLPPKPQLGDLLAKSQTG----DVS 1008

Query: 369  PPPPPPDDIPMFDDSPPPPPPPPVDYED--EEAAVVQYND--PYADGDPAWAP------K 418
            P    P ++ +   S P    P V   D  ++ A    ND  P     P   P      K
Sbjct: 1009 PKAQQPSEVTL--KSHPLDLSPNVQSRDAIQKQASEDSNDLTPTLPETPVPLPRKINTGK 1066

Query: 419  NYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWY----EGVCNRVTGLFPGNYV 473
            N + +V  IYD   D DDEL+F+EG +I V  + D  W+    EG   R  G+FP ++V
Sbjct: 1067 NKVRRVKTIYDCQADNDDELTFIEGEVIIVTGEEDQEWWIGHIEGQPER-KGVFPVSFV 1124



 Score = 32.3 bits (72), Expect = 0.98
 Identities = 33/120 (27%), Positives = 40/120 (33%), Gaps = 25/120 (20%)

Query: 272 GPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQN 331
           G + P       YG  T QI    ST S TS                 P     PL  +N
Sbjct: 755 GFSTPRDKQRLSYGAFTNQIFVSTSTDSPTS-----------------PTTEAPPLPPRN 797

Query: 332 SISIAPPPPPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPPPP 391
           +    P  PP       +PL+   +     +  S   PPPPPP       D P P P  P
Sbjct: 798 A-GKGPTGPPST-----LPLSTQTSSGSSTL--SKKRPPPPPPGHKRTLSDPPSPLPHGP 849


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 61/225 (27%), Positives = 86/225 (38%), Gaps = 14/225 (6%)

Query: 170  TLSRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRT 229
            T + T PP    PSPP +   T   +T   TL P   P+ P    T+P    +   P  T
Sbjct: 1527 TTTTTTPPPTTTPSPPTTTPITPPTSTT--TLPPTTTPSPPPTTTTTPPPTTTPSPPTTT 1584

Query: 230  ASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPAAPGSAPGSQYGTMTR 289
                  P T + ++    +  +  +++   P    TPSPPT  P  P ++  +   T T 
Sbjct: 1585 TP---SPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTP 1641

Query: 290  QISRHNSTT---SSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLT 346
                  +TT   ++T S     TPS     +  P     P    + I+  P PP     T
Sbjct: 1642 SPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTP---SSPITTTPSPPTTTMTT 1698

Query: 347  PQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPPPP 391
            P  P T   + +      S T  P PPP    M   SP   P PP
Sbjct: 1699 PS-PTTTPSSPITTTTTPSSTTTPSPPPTT--MTTPSPTTTPSPP 1740



 Score = 60.1 bits (144), Expect = 4e-09
 Identities = 63/249 (25%), Positives = 91/249 (36%), Gaps = 31/249 (12%)

Query: 170  TLSRTNPPTQKPPSPPMSGRGTLGRNT----PYKTLEPVKPPTVPNDYMTSPARLGSQHS 225
            T + T PP    PSPP++   T    T    P  T     P T P+   T+P+   +  S
Sbjct: 1426 TTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPS 1485

Query: 226  PGRTASLNQRPRT-------------HSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIG 272
            P  T +    P T              S ++    +  +  +++   P    TPSPPT  
Sbjct: 1486 PPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTT 1545

Query: 273  PAAPGSAPGSQYGTMTRQISRHNSTT---SSTSSGGYRRTPSVTAQFSAQPHVNGGPLYS 329
            P  P ++  +   T T       +TT   ++T S     TPS     +  P     P   
Sbjct: 1546 PITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPP 1605

Query: 330  QNSISIAPP--PPPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPP 387
              + +  PP   P  P  TP  P T         +  + TP PPP     P    +P PP
Sbjct: 1606 TTTTTTPPPTTTPSPPTTTPITPPTS-----TTTLPPTTTPSPPPTTTTTPPPTTTPSPP 1660

Query: 388  ----PPPPV 392
                P PP+
Sbjct: 1661 TTTTPSPPI 1669



 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 59/222 (26%), Positives = 78/222 (35%), Gaps = 28/222 (12%)

Query: 170  TLSRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRT 229
            T++ T PP    PSPP     T    TP  T  P  P T P    TS   L    +P   
Sbjct: 1590 TITTTTPPPTTTPSPP-----TTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPP 1644

Query: 230  ASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPAAP-GSAPGSQYGTMT 288
             +    P   +  S  +       +++   PI   T  PPT  P++P  + P     TMT
Sbjct: 1645 PTTTTTPPPTTTPSPPT-------TTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMT 1697

Query: 289  RQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQ 348
                  + TT+ +S      TPS T   S  P     P           P PP   +T  
Sbjct: 1698 TP----SPTTTPSSPITTTTTPSSTTTPSPPPTTMTTP------SPTTTPSPPTTTMTTL 1747

Query: 349  IPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPPP 390
             P T         +  +P PP   PP   P    +P  P  P
Sbjct: 1748 PPTT-----TSSPLTTTPLPPSITPPTFSPFSTTTPTTPCVP 1784



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 55/223 (24%), Positives = 74/223 (33%), Gaps = 40/223 (17%)

Query: 171  LSRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTA 230
            ++  +PPT  P  PP          T   TL P   P+ P    T+P    +  SP  T 
Sbjct: 1396 ITTPSPPTTTPSPPP----------TSTTTLPPTTTPSPPTTTTTTPPPTTTP-SPPITT 1444

Query: 231  SLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPAAPGSAPGSQYGTMTRQ 290
            +    P T            +   S+   P    TPSPPT  P+ P + P          
Sbjct: 1445 TTTPPPTT----------TPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPP------- 1487

Query: 291  ISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQIP 350
                 +TT++T       +P  T   +        P  +  S        P P  TP  P
Sbjct: 1488 -----TTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPP 1542

Query: 351  LTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPP---PPPP 390
             T  +          PT  P PPP        +PPP   P PP
Sbjct: 1543 TTTPITPPTSTTTLPPTTTPSPPPTT----TTTPPPTTTPSPP 1581



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 39/156 (25%), Positives = 61/156 (39%), Gaps = 9/156 (5%)

Query: 165  PARTGTLSRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTV-PNDYMTSPARLGSQ 223
            P    T + T PPT  P  PP +        TP  T  P  P T  P+  +T+       
Sbjct: 1625 PITPPTSTTTLPPTTTPSPPPTT------TTTPPPTTTPSPPTTTTPSPPITTTTTPPPT 1678

Query: 224  HSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPP--TIGPAAPGSAPG 281
             +P    +    P T + ++    +  +S  ++   P +  TPSPP  T+   +P + P 
Sbjct: 1679 TTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPS 1738

Query: 282  SQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFS 317
                TMT       S+  +T+      TP   + FS
Sbjct: 1739 PPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFS 1774



 Score = 39.7 bits (91), Expect = 0.006
 Identities = 59/250 (23%), Positives = 94/250 (37%), Gaps = 29/250 (11%)

Query: 165  PARTGTLSRTNPP----TQKPPSPPMSGRGTLGRNTPYKTLEPVKP---PTVPNDYMTSP 217
            P  TGT + T  P    T   P+P  +G  T    TP  T   V P   PT      T+P
Sbjct: 4027 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPTTTP 4085

Query: 218  ARLGSQHSPGRTASLNQRPRTH--------SGSSGGSGSRENSGSSSIGIPIAVPTPSPP 269
                +  +P  T +  Q P T         + +   +G++  + +         PTP+P 
Sbjct: 4086 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 4145

Query: 270  TIGPAAPGSAPGSQYGTMTRQIS----RHNSTTSSTSSGGYRRTPSVTAQFSAQP-HVNG 324
              G   P + P +   T+T   +    +  +TT  T++     TP+ T   +  P H + 
Sbjct: 4146 --GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTST 4203

Query: 325  GPLYSQNSISIAPPPPPMPQL-----TPQIPLTGFVARVQENIADSPTPPPPPPPDDIPM 379
             P+ ++ + S  PP    PQ      +P    T  ++ +   I  + T PP  P      
Sbjct: 4204 API-AELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTT 4262

Query: 380  FDDSPPPPPP 389
                   PPP
Sbjct: 4263 SGGHTLSPPP 4272



 Score = 38.9 bits (89), Expect = 0.010
 Identities = 53/242 (21%), Positives = 87/242 (35%), Gaps = 24/242 (9%)

Query: 165  PARTGTLSRTNPP----TQKPPSPPMSGRGTLGRN--TPYKTLEPVKPPTVPNDYMTSPA 218
            P  TGT + T  P    T   P+P  +G  T      T   T+ P   PT      T+P 
Sbjct: 2049 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2108

Query: 219  RLGSQHSPGRTASLNQRPRTH--------SGSSGGSGSRENSGSSSIGIPIAVPTPSPPT 270
               +  +P  T +  Q P T         + +   +G++  + +         PTP+P  
Sbjct: 2109 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 2166

Query: 271  IGPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQ 330
             G   P + P +   T+T   +   + T +T+      T + T   +        P+   
Sbjct: 2167 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI--T 2224

Query: 331  NSISIAPPPPPMPQLTP-QIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPP 389
             + ++ P P P    TP   P+T         +  +PTP     P   P+   +   P P
Sbjct: 2225 TTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2279

Query: 390  PP 391
             P
Sbjct: 2280 TP 2281



 Score = 38.9 bits (89), Expect = 0.010
 Identities = 53/242 (21%), Positives = 87/242 (35%), Gaps = 24/242 (9%)

Query: 165  PARTGTLSRTNPP----TQKPPSPPMSGRGTLGRN--TPYKTLEPVKPPTVPNDYMTSPA 218
            P  TGT + T  P    T   P+P  +G  T      T   T+ P   PT      T+P 
Sbjct: 2210 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2269

Query: 219  RLGSQHSPGRTASLNQRPRTH--------SGSSGGSGSRENSGSSSIGIPIAVPTPSPPT 270
               +  +P  T +  Q P T         + +   +G++  + +         PTP+P  
Sbjct: 2270 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 2327

Query: 271  IGPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQ 330
             G   P + P +   T+T   +   + T +T+      T + T   +        P+   
Sbjct: 2328 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI--T 2385

Query: 331  NSISIAPPPPPMPQLTP-QIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPP 389
             + ++ P P P    TP   P+T         +  +PTP     P   P+   +   P P
Sbjct: 2386 TTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2440

Query: 390  PP 391
             P
Sbjct: 2441 TP 2442



 Score = 38.9 bits (89), Expect = 0.010
 Identities = 53/242 (21%), Positives = 87/242 (35%), Gaps = 24/242 (9%)

Query: 165  PARTGTLSRTNPP----TQKPPSPPMSGRGTLGRN--TPYKTLEPVKPPTVPNDYMTSPA 218
            P  TGT + T  P    T   P+P  +G  T      T   T+ P   PT      T+P 
Sbjct: 2371 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2430

Query: 219  RLGSQHSPGRTASLNQRPRTH--------SGSSGGSGSRENSGSSSIGIPIAVPTPSPPT 270
               +  +P  T +  Q P T         + +   +G++  + +         PTP+P  
Sbjct: 2431 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 2488

Query: 271  IGPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQ 330
             G   P + P +   T+T   +   + T +T+      T + T   +        P+   
Sbjct: 2489 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI--T 2546

Query: 331  NSISIAPPPPPMPQLTP-QIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPP 389
             + ++ P P P    TP   P+T         +  +PTP     P   P+   +   P P
Sbjct: 2547 TTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2601

Query: 390  PP 391
             P
Sbjct: 2602 TP 2603



 Score = 38.9 bits (89), Expect = 0.010
 Identities = 53/242 (21%), Positives = 87/242 (35%), Gaps = 24/242 (9%)

Query: 165  PARTGTLSRTNPP----TQKPPSPPMSGRGTLGRN--TPYKTLEPVKPPTVPNDYMTSPA 218
            P  TGT + T  P    T   P+P  +G  T      T   T+ P   PT      T+P 
Sbjct: 2532 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2591

Query: 219  RLGSQHSPGRTASLNQRPRTH--------SGSSGGSGSRENSGSSSIGIPIAVPTPSPPT 270
               +  +P  T +  Q P T         + +   +G++  + +         PTP+P  
Sbjct: 2592 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 2649

Query: 271  IGPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQ 330
             G   P + P +   T+T   +   + T +T+      T + T   +        P+   
Sbjct: 2650 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI--T 2707

Query: 331  NSISIAPPPPPMPQLTP-QIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPP 389
             + ++ P P P    TP   P+T         +  +PTP     P   P+   +   P P
Sbjct: 2708 TTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2762

Query: 390  PP 391
             P
Sbjct: 2763 TP 2764



 Score = 38.9 bits (89), Expect = 0.010
 Identities = 53/242 (21%), Positives = 87/242 (35%), Gaps = 24/242 (9%)

Query: 165  PARTGTLSRTNPP----TQKPPSPPMSGRGTLGRN--TPYKTLEPVKPPTVPNDYMTSPA 218
            P  TGT + T  P    T   P+P  +G  T      T   T+ P   PT      T+P 
Sbjct: 2693 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2752

Query: 219  RLGSQHSPGRTASLNQRPRTH--------SGSSGGSGSRENSGSSSIGIPIAVPTPSPPT 270
               +  +P  T +  Q P T         + +   +G++  + +         PTP+P  
Sbjct: 2753 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 2810

Query: 271  IGPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQ 330
             G   P + P +   T+T   +   + T +T+      T + T   +        P+   
Sbjct: 2811 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI--T 2868

Query: 331  NSISIAPPPPPMPQLTP-QIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPP 389
             + ++ P P P    TP   P+T         +  +PTP     P   P+   +   P P
Sbjct: 2869 TTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2923

Query: 390  PP 391
             P
Sbjct: 2924 TP 2925



 Score = 38.9 bits (89), Expect = 0.010
 Identities = 53/242 (21%), Positives = 87/242 (35%), Gaps = 24/242 (9%)

Query: 165  PARTGTLSRTNPP----TQKPPSPPMSGRGTLGRN--TPYKTLEPVKPPTVPNDYMTSPA 218
            P  TGT + T  P    T   P+P  +G  T      T   T+ P   PT      T+P 
Sbjct: 2854 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2913

Query: 219  RLGSQHSPGRTASLNQRPRTH--------SGSSGGSGSRENSGSSSIGIPIAVPTPSPPT 270
               +  +P  T +  Q P T         + +   +G++  + +         PTP+P  
Sbjct: 2914 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 2971

Query: 271  IGPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQ 330
             G   P + P +   T+T   +   + T +T+      T + T   +        P+   
Sbjct: 2972 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI--T 3029

Query: 331  NSISIAPPPPPMPQLTP-QIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPP 389
             + ++ P P P    TP   P+T         +  +PTP     P   P+   +   P P
Sbjct: 3030 TTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3084

Query: 390  PP 391
             P
Sbjct: 3085 TP 3086



 Score = 38.9 bits (89), Expect = 0.010
 Identities = 53/242 (21%), Positives = 87/242 (35%), Gaps = 24/242 (9%)

Query: 165  PARTGTLSRTNPP----TQKPPSPPMSGRGTLGRN--TPYKTLEPVKPPTVPNDYMTSPA 218
            P  TGT + T  P    T   P+P  +G  T      T   T+ P   PT      T+P 
Sbjct: 3015 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3074

Query: 219  RLGSQHSPGRTASLNQRPRTH--------SGSSGGSGSRENSGSSSIGIPIAVPTPSPPT 270
               +  +P  T +  Q P T         + +   +G++  + +         PTP+P  
Sbjct: 3075 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 3132

Query: 271  IGPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQ 330
             G   P + P +   T+T   +   + T +T+      T + T   +        P+   
Sbjct: 3133 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI--T 3190

Query: 331  NSISIAPPPPPMPQLTP-QIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPP 389
             + ++ P P P    TP   P+T         +  +PTP     P   P+   +   P P
Sbjct: 3191 TTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3245

Query: 390  PP 391
             P
Sbjct: 3246 TP 3247



 Score = 38.9 bits (89), Expect = 0.010
 Identities = 53/242 (21%), Positives = 87/242 (35%), Gaps = 24/242 (9%)

Query: 165  PARTGTLSRTNPP----TQKPPSPPMSGRGTLGRN--TPYKTLEPVKPPTVPNDYMTSPA 218
            P  TGT + T  P    T   P+P  +G  T      T   T+ P   PT      T+P 
Sbjct: 3176 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3235

Query: 219  RLGSQHSPGRTASLNQRPRTH--------SGSSGGSGSRENSGSSSIGIPIAVPTPSPPT 270
               +  +P  T +  Q P T         + +   +G++  + +         PTP+P  
Sbjct: 3236 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 3293

Query: 271  IGPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQ 330
             G   P + P +   T+T   +   + T +T+      T + T   +        P+   
Sbjct: 3294 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI--T 3351

Query: 331  NSISIAPPPPPMPQLTP-QIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPP 389
             + ++ P P P    TP   P+T         +  +PTP     P   P+   +   P P
Sbjct: 3352 TTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3406

Query: 390  PP 391
             P
Sbjct: 3407 TP 3408



 Score = 38.9 bits (89), Expect = 0.010
 Identities = 53/242 (21%), Positives = 87/242 (35%), Gaps = 24/242 (9%)

Query: 165  PARTGTLSRTNPP----TQKPPSPPMSGRGTLGRN--TPYKTLEPVKPPTVPNDYMTSPA 218
            P  TGT + T  P    T   P+P  +G  T      T   T+ P   PT      T+P 
Sbjct: 3337 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3396

Query: 219  RLGSQHSPGRTASLNQRPRTH--------SGSSGGSGSRENSGSSSIGIPIAVPTPSPPT 270
               +  +P  T +  Q P T         + +   +G++  + +         PTP+P  
Sbjct: 3397 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 3454

Query: 271  IGPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQ 330
             G   P + P +   T+T   +   + T +T+      T + T   +        P+   
Sbjct: 3455 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI--T 3512

Query: 331  NSISIAPPPPPMPQLTP-QIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPP 389
             + ++ P P P    TP   P+T         +  +PTP     P   P+   +   P P
Sbjct: 3513 TTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3567

Query: 390  PP 391
             P
Sbjct: 3568 TP 3569



 Score = 38.9 bits (89), Expect = 0.010
 Identities = 53/242 (21%), Positives = 87/242 (35%), Gaps = 24/242 (9%)

Query: 165  PARTGTLSRTNPP----TQKPPSPPMSGRGTLGRN--TPYKTLEPVKPPTVPNDYMTSPA 218
            P  TGT + T  P    T   P+P  +G  T      T   T+ P   PT      T+P 
Sbjct: 3498 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3557

Query: 219  RLGSQHSPGRTASLNQRPRTH--------SGSSGGSGSRENSGSSSIGIPIAVPTPSPPT 270
               +  +P  T +  Q P T         + +   +G++  + +         PTP+P  
Sbjct: 3558 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 3615

Query: 271  IGPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQ 330
             G   P + P +   T+T   +   + T +T+      T + T   +        P+   
Sbjct: 3616 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI--T 3673

Query: 331  NSISIAPPPPPMPQLTP-QIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPP 389
             + ++ P P P    TP   P+T         +  +PTP     P   P+   +   P P
Sbjct: 3674 TTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3728

Query: 390  PP 391
             P
Sbjct: 3729 TP 3730



 Score = 38.9 bits (89), Expect = 0.010
 Identities = 53/242 (21%), Positives = 87/242 (35%), Gaps = 24/242 (9%)

Query: 165  PARTGTLSRTNPP----TQKPPSPPMSGRGTLGRN--TPYKTLEPVKPPTVPNDYMTSPA 218
            P  TGT + T  P    T   P+P  +G  T      T   T+ P   PT      T+P 
Sbjct: 3659 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3718

Query: 219  RLGSQHSPGRTASLNQRPRTH--------SGSSGGSGSRENSGSSSIGIPIAVPTPSPPT 270
               +  +P  T +  Q P T         + +   +G++  + +         PTP+P  
Sbjct: 3719 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 3776

Query: 271  IGPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQ 330
             G   P + P +   T+T   +   + T +T+      T + T   +        P+   
Sbjct: 3777 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI--T 3834

Query: 331  NSISIAPPPPPMPQLTP-QIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPP 389
             + ++ P P P    TP   P+T         +  +PTP     P   P+   +   P P
Sbjct: 3835 TTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3889

Query: 390  PP 391
             P
Sbjct: 3890 TP 3891



 Score = 38.9 bits (89), Expect = 0.010
 Identities = 53/242 (21%), Positives = 87/242 (35%), Gaps = 24/242 (9%)

Query: 165  PARTGTLSRTNPP----TQKPPSPPMSGRGTLGRN--TPYKTLEPVKPPTVPNDYMTSPA 218
            P  TGT + T  P    T   P+P  +G  T      T   T+ P   PT      T+P 
Sbjct: 3820 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3879

Query: 219  RLGSQHSPGRTASLNQRPRTH--------SGSSGGSGSRENSGSSSIGIPIAVPTPSPPT 270
               +  +P  T +  Q P T         + +   +G++  + +         PTP+P  
Sbjct: 3880 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 3937

Query: 271  IGPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQ 330
             G   P + P +   T+T   +   + T +T+      T + T   +        P+   
Sbjct: 3938 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI--T 3995

Query: 331  NSISIAPPPPPMPQLTP-QIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPP 389
             + ++ P P P    TP   P+T         +  +PTP     P   P+   +   P P
Sbjct: 3996 TTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 4050

Query: 390  PP 391
             P
Sbjct: 4051 TP 4052



 Score = 37.7 bits (86), Expect = 0.023
 Identities = 51/234 (21%), Positives = 80/234 (34%), Gaps = 31/234 (13%)

Query: 165  PARTGTLSRTNPP----TQKPPSPPMSGRGTLGRN--TPYKTLEPVKPPTVPNDYMTSPA 218
            P  TGT + T  P    T   P+P  +G  T      T   T+ P   PT      T+P 
Sbjct: 3981 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 4040

Query: 219  RLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPAAPGS 278
               +  +P  T +  Q P T   ++                     TP+P   G   P +
Sbjct: 4041 TTTTTVTPTPTPTGTQTPTTTPITT-----------------TTTVTPTPTPTGTQTPTT 4083

Query: 279  APGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPP 338
             P +   T+T   +   + T +T+      T + T   +        P+    + ++ P 
Sbjct: 4084 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI--TTTTTVTPT 4141

Query: 339  PPPMPQLTP-QIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPPPP 391
            P P    TP   P+T         +  +PTP     P   P+   +   P P P
Sbjct: 4142 PTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 4190



 Score = 37.4 bits (85), Expect = 0.030
 Identities = 51/243 (20%), Positives = 84/243 (34%), Gaps = 28/243 (11%)

Query: 168  TGTLSRTNPPTQKP----------PSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSP 217
            T T     PPT  P          P+P  +   T    T   T+ P   PT      T+P
Sbjct: 1887 TTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 1946

Query: 218  ARLGSQHSPGRTASLNQRPRTH--------SGSSGGSGSRENSGSSSIGIPIAVPTPSPP 269
                +  +P  T +  Q P T         + +   +G++  + +         PTP+P 
Sbjct: 1947 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP- 2005

Query: 270  TIGPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYS 329
              G   P + P +   T+T   +   + T +T+      T + T   +        P+  
Sbjct: 2006 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-- 2062

Query: 330  QNSISIAPPPPPMPQLTP-QIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPP 388
              + ++ P P P    TP   P+T         +  +PTP     P   P+   +   P 
Sbjct: 2063 TTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2117

Query: 389  PPP 391
            P P
Sbjct: 2118 PTP 2120



 Score = 35.8 bits (81), Expect = 0.089
 Identities = 61/237 (25%), Positives = 81/237 (34%), Gaps = 32/237 (13%)

Query: 165  PARTGT-----LSRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPAR 219
            P  T T     L+ +NPP +   S P + R T    T   TL    PP +    MTS A 
Sbjct: 4198 PTHTSTAPIAELTTSNPPPES--STPQTSRSTSSPLTESTTLLSTLPPAIE---MTSTAP 4252

Query: 220  LGSQHSPGRTA---SLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPA-A 275
              +  +P  T+   +L+  P T +   G       +GSSS   P  V T +     P   
Sbjct: 4253 PSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPT 4312

Query: 276  PGSAPGSQYGTMTRQISRH-------NSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLY 328
            P S P     T  R            N T  +     Y  T   T  F     ++    +
Sbjct: 4313 PLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYF-VNCSLSCTLEF 4371

Query: 329  SQNSISIAPPPPPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPP 385
               S    P P P P  +   P          +    PTP   PP  + P FD  PP
Sbjct: 4372 YNWSCPSTPSPTPTPSKSTPTP------SKPSSTPSKPTPGTKPP--ECPDFD--PP 4418


>gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]
          Length = 1220

 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 26/52 (50%), Positives = 35/52 (67%)

Query: 423  KVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVE 474
            +V+ +YDYT   DDEL+F +G II V+ K D  W++G  N   GLFP NYV+
Sbjct: 1159 QVIGMYDYTAQNDDELAFNKGQIINVLNKEDPDWWKGEVNGQVGLFPSNYVK 1210



 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 23/61 (37%), Positives = 34/61 (55%), Gaps = 1/61 (1%)

Query: 413  PAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNY 472
            PA  P    E+ +A+Y Y   +  +L+F +G +I V KK+ D W+ G      G+FP NY
Sbjct: 996  PAAKPVVSGEEFIAMYTYESSEQGDLTFQQGDVILVTKKDGD-WWTGTVGDKAGVFPSNY 1054

Query: 473  V 473
            V
Sbjct: 1055 V 1055



 Score = 38.9 bits (89), Expect = 0.010
 Identities = 23/62 (37%), Positives = 32/62 (51%), Gaps = 7/62 (11%)

Query: 418  KNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVC-----NRVTGLFPGNY 472
            K  I +V+A   YT    ++L+   G +I + KKN  GW+EG        R  G FP NY
Sbjct: 1075 KPEIAQVIA--SYTATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANY 1132

Query: 473  VE 474
            V+
Sbjct: 1133 VK 1134



 Score = 33.9 bits (76), Expect = 0.34
 Identities = 18/58 (31%), Positives = 25/58 (43%), Gaps = 7/58 (12%)

Query: 426 AIYDYTKDKDDELSFMEGAIIYV-------IKKNDDGWYEGVCNRVTGLFPGNYVESI 476
           A+Y +     DE++   G I+ V        +  + GW  G     TG FP NY E I
Sbjct: 747 ALYPFESRSHDEITIQPGDIVMVKGEWVDESQTGEPGWLGGELKGKTGWFPANYAEKI 804



 Score = 33.5 bits (75), Expect = 0.44
 Identities = 17/51 (33%), Positives = 29/51 (56%), Gaps = 1/51 (1%)

Query: 426 AIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESI 476
           A+Y +   KD+ L+F +  +I V+++ D  W+ G      G FP +YV+ I
Sbjct: 920 ALYPWRAKKDNHLNFNKNDVITVLEQQDMWWF-GEVQGQKGWFPKSYVKLI 969


>gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]
          Length = 1721

 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 26/52 (50%), Positives = 35/52 (67%)

Query: 423  KVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVE 474
            +V+ +YDYT   DDEL+F +G II V+ K D  W++G  N   GLFP NYV+
Sbjct: 1159 QVIGMYDYTAQNDDELAFNKGQIINVLNKEDPDWWKGEVNGQVGLFPSNYVK 1210



 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 23/61 (37%), Positives = 34/61 (55%), Gaps = 1/61 (1%)

Query: 413  PAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNY 472
            PA  P    E+ +A+Y Y   +  +L+F +G +I V KK+ D W+ G      G+FP NY
Sbjct: 996  PAAKPVVSGEEFIAMYTYESSEQGDLTFQQGDVILVTKKDGD-WWTGTVGDKAGVFPSNY 1054

Query: 473  V 473
            V
Sbjct: 1055 V 1055



 Score = 38.9 bits (89), Expect = 0.010
 Identities = 23/62 (37%), Positives = 32/62 (51%), Gaps = 7/62 (11%)

Query: 418  KNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVC-----NRVTGLFPGNY 472
            K  I +V+A   YT    ++L+   G +I + KKN  GW+EG        R  G FP NY
Sbjct: 1075 KPEIAQVIA--SYTATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANY 1132

Query: 473  VE 474
            V+
Sbjct: 1133 VK 1134



 Score = 33.9 bits (76), Expect = 0.34
 Identities = 18/58 (31%), Positives = 25/58 (43%), Gaps = 7/58 (12%)

Query: 426 AIYDYTKDKDDELSFMEGAIIYV-------IKKNDDGWYEGVCNRVTGLFPGNYVESI 476
           A+Y +     DE++   G I+ V        +  + GW  G     TG FP NY E I
Sbjct: 747 ALYPFESRSHDEITIQPGDIVMVKGEWVDESQTGEPGWLGGELKGKTGWFPANYAEKI 804



 Score = 33.5 bits (75), Expect = 0.44
 Identities = 17/51 (33%), Positives = 29/51 (56%), Gaps = 1/51 (1%)

Query: 426 AIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESI 476
           A+Y +   KD+ L+F +  +I V+++ D  W+ G      G FP +YV+ I
Sbjct: 920 ALYPWRAKKDNHLNFNKNDVITVLEQQDMWWF-GEVQGQKGWFPKSYVKLI 969


>gi|224586851 sorbin and SH3 domain containing 2 isoform 6 [Homo
           sapiens]
          Length = 824

 Score = 60.1 bits (144), Expect = 4e-09
 Identities = 75/330 (22%), Positives = 117/330 (35%), Gaps = 22/330 (6%)

Query: 156 LKAKHGNNQP-ARTGTLSRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYM 214
           L   H +N P A     S   PP   PP PP+  R     +T     +P         + 
Sbjct: 328 LSKSHSDNSPNAFKDASSPVPPPHVPPPVPPLRPRDR--SSTEKHDWDPPDRKVDTRKFR 385

Query: 215 TSPARLGSQHSPGRTASLNQR-----PRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPP 269
           + P  +  ++ PG+++ L        P T +      G R+   SS +G     P+P P 
Sbjct: 386 SEPRSI-FEYEPGKSSILQHERPPPLPTTPTPVPREPG-RKPLSSSRLGEVTGSPSPPPR 443

Query: 270 TIGPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYS 329
           +  P     AP     + TR   +        SSG +            Q  ++      
Sbjct: 444 SGAPTPSSRAPAL---SPTRPPKKPLDYVQDHSSGVFNEASLY------QSSIDRSLERP 494

Query: 330 QNSISIAPPPPPMPQLTPQI-PLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPP 388
            +S S+A       +  P + P  G   +     +      P         F  S P  P
Sbjct: 495 MSSASMASDFRKRRKSEPAVGPPRGLGDQSASRTSPGRVDLPGSSTTLTKSFTSSSPSSP 554

Query: 389 PPPVDYEDEEAAVVQYNDP--YADGDPAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAII 446
               D E   +      D    A  +    P+       A+YD+      ELSF +G  +
Sbjct: 555 SRAKDRESPRSYSSTLTDMGRSAPRERRGTPEKEKLPAKAVYDFKAQTSKELSFKKGDTV 614

Query: 447 YVIKKNDDGWYEGVCNRVTGLFPGNYVESI 476
           Y+++K D  WYEG  +   G+FP +YVE +
Sbjct: 615 YILRKIDQNWYEGEHHGRVGIFPISYVEKL 644



 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 34/96 (35%), Positives = 47/96 (48%), Gaps = 8/96 (8%)

Query: 386 PPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNYI---EKVVAIYDYTKDKDDELSFME 442
           P PP P  Y  +    +  N P     P +  +N     E   A+Y+YT   +DEL   E
Sbjct: 732 PDPPIPHSYSSDRIHSLSSNKPQR---PVFTHENIQGGGEPFQALYNYTPRNEDELELRE 788

Query: 443 GAIIYVIKKNDDGWYEGVCNRVT--GLFPGNYVESI 476
             +I V++K DDGW+ G   R    G FPGNYV+ +
Sbjct: 789 SDVIDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL 824



 Score = 52.4 bits (124), Expect = 9e-07
 Identities = 81/342 (23%), Positives = 116/342 (33%), Gaps = 78/342 (22%)

Query: 172 SRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPG--RT 229
           SR    T  P  PP SG  T     P   L P +PP  P DY+         HS G    
Sbjct: 429 SRLGEVTGSPSPPPRSGAPTPSSRAP--ALSPTRPPKKPLDYV-------QDHSSGVFNE 479

Query: 230 ASLNQ--------RPRTHSGSSGGSGSRENSG------------SSSIGIPIAVPTP-SP 268
           ASL Q        RP + +  +     R  S             S+S   P  V  P S 
Sbjct: 480 ASLYQSSIDRSLERPMSSASMASDFRKRRKSEPAVGPPRGLGDQSASRTSPGRVDLPGSS 539

Query: 269 PTIGPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLY 328
            T+  +   S+P S      R+  R  S+T +       R    T +    P        
Sbjct: 540 TTLTKSFTSSSPSSPSRAKDRESPRSYSSTLTDMGRSAPRERRGTPEKEKLPAKAVYDFK 599

Query: 329 SQNSISIAPPPPPMPQLTPQIPLTGFVARVQENIADSP-------TPPPPPPPDDIPMFD 381
           +Q S  ++        +  +I    +       +   P       TPP    P       
Sbjct: 600 AQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVEKLTPPEKAQP------- 652

Query: 382 DSPPPPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNYIEKVVAIYDYTKDKDDELSFM 441
            + PPPP  P +                           I + +A Y++  D + ELS  
Sbjct: 653 -ARPPPPAQPGE---------------------------IGEAIAKYNFNADTNVELSLR 684

Query: 442 EGAIIYVIKKNDDGWYEGV---CNRVTGLFPGNYVESIMHYT 480
           +G  + ++K+ D  WYEG     NR  G+FP +YVE +   T
Sbjct: 685 KGDRVILLKRVDQNWYEGKIPGTNR-QGIFPVSYVEVVKKNT 725



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 47/200 (23%), Positives = 74/200 (37%), Gaps = 27/200 (13%)

Query: 207 PTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTP 266
           P   N  + +P      H   +T +     ++HS +S  +       +SS   P  VP P
Sbjct: 300 PYTYNAGLYNPPYSAQSHPAAKTQTYRPLSKSHSDNSPNAFK----DASSPVPPPHVPPP 355

Query: 267 SPPTIGPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGP 326
            PP + P    S     +    R++      +   S   Y    S   Q    P      
Sbjct: 356 VPP-LRPRDRSSTEKHDWDPPDRKVDTRKFRSEPRSIFEYEPGKSSILQHERPP------ 408

Query: 327 LYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQENIADSPTPPP----PPPPDDIPMFDD 382
                   +   P P+P+   + PL+   +R+ E +  SP+PPP    P P    P    
Sbjct: 409 -------PLPTTPTPVPREPGRKPLSS--SRLGE-VTGSPSPPPRSGAPTPSSRAPAL-- 456

Query: 383 SPPPPPPPPVDYEDEEAAVV 402
           SP  PP  P+DY  + ++ V
Sbjct: 457 SPTRPPKKPLDYVQDHSSGV 476


>gi|224586846 sorbin and SH3 domain containing 2 isoform 4 [Homo
           sapiens]
          Length = 731

 Score = 60.1 bits (144), Expect = 4e-09
 Identities = 75/330 (22%), Positives = 117/330 (35%), Gaps = 22/330 (6%)

Query: 156 LKAKHGNNQP-ARTGTLSRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYM 214
           L   H +N P A     S   PP   PP PP+  R     +T     +P         + 
Sbjct: 235 LSKSHSDNSPNAFKDASSPVPPPHVPPPVPPLRPRDR--SSTEKHDWDPPDRKVDTRKFR 292

Query: 215 TSPARLGSQHSPGRTASLNQR-----PRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPP 269
           + P  +  ++ PG+++ L        P T +      G R+   SS +G     P+P P 
Sbjct: 293 SEPRSI-FEYEPGKSSILQHERPPPLPTTPTPVPREPG-RKPLSSSRLGEVTGSPSPPPR 350

Query: 270 TIGPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYS 329
           +  P     AP     + TR   +        SSG +            Q  ++      
Sbjct: 351 SGAPTPSSRAPAL---SPTRPPKKPLDYVQDHSSGVFNEASLY------QSSIDRSLERP 401

Query: 330 QNSISIAPPPPPMPQLTPQI-PLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPP 388
            +S S+A       +  P + P  G   +     +      P         F  S P  P
Sbjct: 402 MSSASMASDFRKRRKSEPAVGPPRGLGDQSASRTSPGRVDLPGSSTTLTKSFTSSSPSSP 461

Query: 389 PPPVDYEDEEAAVVQYNDP--YADGDPAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAII 446
               D E   +      D    A  +    P+       A+YD+      ELSF +G  +
Sbjct: 462 SRAKDRESPRSYSSTLTDMGRSAPRERRGTPEKEKLPAKAVYDFKAQTSKELSFKKGDTV 521

Query: 447 YVIKKNDDGWYEGVCNRVTGLFPGNYVESI 476
           Y+++K D  WYEG  +   G+FP +YVE +
Sbjct: 522 YILRKIDQNWYEGEHHGRVGIFPISYVEKL 551



 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 34/96 (35%), Positives = 47/96 (48%), Gaps = 8/96 (8%)

Query: 386 PPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNYI---EKVVAIYDYTKDKDDELSFME 442
           P PP P  Y  +    +  N P     P +  +N     E   A+Y+YT   +DEL   E
Sbjct: 639 PDPPIPHSYSSDRIHSLSSNKPQR---PVFTHENIQGGGEPFQALYNYTPRNEDELELRE 695

Query: 443 GAIIYVIKKNDDGWYEGVCNRVT--GLFPGNYVESI 476
             +I V++K DDGW+ G   R    G FPGNYV+ +
Sbjct: 696 SDVIDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL 731



 Score = 52.4 bits (124), Expect = 9e-07
 Identities = 81/342 (23%), Positives = 116/342 (33%), Gaps = 78/342 (22%)

Query: 172 SRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPG--RT 229
           SR    T  P  PP SG  T     P   L P +PP  P DY+         HS G    
Sbjct: 336 SRLGEVTGSPSPPPRSGAPTPSSRAP--ALSPTRPPKKPLDYV-------QDHSSGVFNE 386

Query: 230 ASLNQ--------RPRTHSGSSGGSGSRENSG------------SSSIGIPIAVPTP-SP 268
           ASL Q        RP + +  +     R  S             S+S   P  V  P S 
Sbjct: 387 ASLYQSSIDRSLERPMSSASMASDFRKRRKSEPAVGPPRGLGDQSASRTSPGRVDLPGSS 446

Query: 269 PTIGPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLY 328
            T+  +   S+P S      R+  R  S+T +       R    T +    P        
Sbjct: 447 TTLTKSFTSSSPSSPSRAKDRESPRSYSSTLTDMGRSAPRERRGTPEKEKLPAKAVYDFK 506

Query: 329 SQNSISIAPPPPPMPQLTPQIPLTGFVARVQENIADSP-------TPPPPPPPDDIPMFD 381
           +Q S  ++        +  +I    +       +   P       TPP    P       
Sbjct: 507 AQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVEKLTPPEKAQP------- 559

Query: 382 DSPPPPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNYIEKVVAIYDYTKDKDDELSFM 441
            + PPPP  P +                           I + +A Y++  D + ELS  
Sbjct: 560 -ARPPPPAQPGE---------------------------IGEAIAKYNFNADTNVELSLR 591

Query: 442 EGAIIYVIKKNDDGWYEGV---CNRVTGLFPGNYVESIMHYT 480
           +G  + ++K+ D  WYEG     NR  G+FP +YVE +   T
Sbjct: 592 KGDRVILLKRVDQNWYEGKIPGTNR-QGIFPVSYVEVVKKNT 632



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 47/200 (23%), Positives = 74/200 (37%), Gaps = 27/200 (13%)

Query: 207 PTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTP 266
           P   N  + +P      H   +T +     ++HS +S  +       +SS   P  VP P
Sbjct: 207 PYTYNAGLYNPPYSAQSHPAAKTQTYRPLSKSHSDNSPNAFK----DASSPVPPPHVPPP 262

Query: 267 SPPTIGPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGP 326
            PP + P    S     +    R++      +   S   Y    S   Q    P      
Sbjct: 263 VPP-LRPRDRSSTEKHDWDPPDRKVDTRKFRSEPRSIFEYEPGKSSILQHERPP------ 315

Query: 327 LYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQENIADSPTPPP----PPPPDDIPMFDD 382
                   +   P P+P+   + PL+   +R+ E +  SP+PPP    P P    P    
Sbjct: 316 -------PLPTTPTPVPREPGRKPLSS--SRLGE-VTGSPSPPPRSGAPTPSSRAPAL-- 363

Query: 383 SPPPPPPPPVDYEDEEAAVV 402
           SP  PP  P+DY  + ++ V
Sbjct: 364 SPTRPPKKPLDYVQDHSSGV 383


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 60.1 bits (144), Expect = 4e-09
 Identities = 61/220 (27%), Positives = 82/220 (37%), Gaps = 32/220 (14%)

Query: 175 NPPTQKPPSPPMSGRGTLGRNTP-YKTLEPVK-PPTVPNDYMTSPARLGSQHSPGRTA-S 231
           +PP Q  PSPP+S   T     P    L P++ PP+ P     SP    S  +P   A  
Sbjct: 600 SPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVH 659

Query: 232 LNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPAAPGSAPGSQYGTMTRQI 291
           L Q P +   S                 P+  P  SPP   P +P + P SQ       +
Sbjct: 660 LLQAPFSPPPSP----------------PVQAPF-SPPASPPVSPSATPPSQ---APPSL 699

Query: 292 SRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQIPL 351
           +        +       +PS T    A P +   PL       + P PP  P ++P    
Sbjct: 700 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPL------QVPPSPPASPPMSPSATP 753

Query: 352 TGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPPPP 391
                RV   +A  P   PP PP  +PM   + PPP  PP
Sbjct: 754 P---PRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPP 790



 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 67/246 (27%), Positives = 93/246 (37%), Gaps = 29/246 (11%)

Query: 167 RTGTLSRTNPPTQKPPS--PPMSGRGTLGRNTPYKTLEPVKPPT---VPNDYMTSPARLG 221
           +T   S T PP +  PS  PP     +    TP+    P   P     P   +T+P    
Sbjct: 524 QTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTP---- 579

Query: 222 SQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTP-SPPTIG-------P 273
               P  T S    P   +  +  S   +   S  +  P+A P P +PP +        P
Sbjct: 580 ----PPETPSSIATPPPQAPPALASPPLQGLPSPPLS-PLATPPPQAPPXLALPPLQAPP 634

Query: 274 AAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFS--AQPHVNGGPLY-SQ 330
           + P S P S   T + Q     +     +      +P V A FS  A P V+      SQ
Sbjct: 635 SPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQ 694

Query: 331 NSISIAPPP---PPMPQLTPQI-PLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPP 386
              S+A PP   PP P  +P + P      +    +A  P   PP PP   PM   + PP
Sbjct: 695 APPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPP 754

Query: 387 PPPPPV 392
           P  PP+
Sbjct: 755 PRVPPL 760



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 59/245 (24%), Positives = 83/245 (33%), Gaps = 35/245 (14%)

Query: 169 GTLSRTNPPTQKPPSPPMSGR----GT-LGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQ 223
           G    T+ PT   PSP M+ R    GT +G   P  +  P  P   P   ++S     S+
Sbjct: 159 GARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSS----ASE 214

Query: 224 HSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPAAPGSAPGSQ 283
           HS    +   +R  +  G      SR  S S       A P  SP   GP+A G+     
Sbjct: 215 HSTTEPSPAARRRPSAGGGLQRPASRSLSSS-------ATPLSSPARSGPSARGTPRAPA 267

Query: 284 YGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPP---- 339
           + +  +            +       P++    S+ P     P  S       PPP    
Sbjct: 268 HPSQPKPKGLQALRPPQVTPPRKDAAPAL-GPLSSSPLATPSP--SGTKARPVPPPDNAA 324

Query: 340 -------PPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPP--- 389
                  PP P L   +PL         ++   P+PP  PP    P     P   PP   
Sbjct: 325 TPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQ 384

Query: 390 --PPV 392
             PP+
Sbjct: 385 TIPPI 389



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 63/223 (28%), Positives = 82/223 (36%), Gaps = 37/223 (16%)

Query: 176 PPTQKPPSPP----MSGRGTLG-RNTPYKTLEPVK-PPTVPNDYMTSPARLGSQHSPGRT 229
           PP Q PPSPP    MS   T   R  P     P++ PP+ P     SP       +P   
Sbjct: 733 PPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPAL 792

Query: 230 AS--LNQRPRTHSGSSGGSGSRENSGSSSIGI-PIAVPTPSPPTIGPAAPGSAPGSQYGT 286
           A+  L   P   S  +   G    S S+S+ + P+A P P  P +  A     P S   +
Sbjct: 793 ATPPLQALP---SPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPAS 849

Query: 287 MTRQISRHNSTTS-STSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQL 345
            T Q  R   T    TS  G R T                       +++AP PPP P  
Sbjct: 850 PTLQAPRRPPTPGPDTSVSGPRLT-----------------------LALAPGPPPPPSR 886

Query: 346 TPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPP 388
           +P   L+G       + A S TP      D  P    +  PPP
Sbjct: 887 SPSSTLSGPDLAGHSSSATS-TPEELRGYDSGPEGGAAASPPP 928



 Score = 42.7 bits (99), Expect = 7e-04
 Identities = 64/280 (22%), Positives = 87/280 (31%), Gaps = 62/280 (22%)

Query: 167 RTGTLSRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSP 226
           R G +     P   P + P    GT  RN   +     +    P    TSP   G   SP
Sbjct: 61  RAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSP---GPVSSP 117

Query: 227 GRTASLNQRP-----------------------------------RTHSGSSGGSGS--- 248
           GR AS   RP                                   R  SG + G+ S   
Sbjct: 118 GR-ASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAM 176

Query: 249 --RENSGSSSIGIPIAVPT--PSPPTIGPAAPGSAPG---------------SQYGTMTR 289
             R  +  + +G+P   P+  P PPT GP    S+                 S  G + R
Sbjct: 177 ARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQR 236

Query: 290 QISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQI 349
             SR  S++++  S   R  PS      A  H +        ++      PP     P +
Sbjct: 237 PASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPAL 296

Query: 350 -PLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPP 388
            PL+               P PPP     P+    PP PP
Sbjct: 297 GPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPP 336



 Score = 37.4 bits (85), Expect = 0.030
 Identities = 56/241 (23%), Positives = 84/241 (34%), Gaps = 35/241 (14%)

Query: 163 NQPARTGTLSRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGS 222
           + PAR+G  +R  P     PS P             K L+ ++PP V      +P R  +
Sbjct: 250 SSPARSGPSARGTPRAPAHPSQPKP-----------KGLQALRPPQV------TPPRKDA 292

Query: 223 QHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPAAPGSAPGS 282
             + G  +S      + SG+        ++ ++ +  P  +P PSPP   P     AP S
Sbjct: 293 APALGPLSSSPLATPSPSGTKARPVPPPDNAATPL--PATLP-PSPPLATPLP--LAPPS 347

Query: 283 QYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPM 342
                + Q       T  + +     TP + A  S Q        +S  S S+  PP P+
Sbjct: 348 PSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPL 407

Query: 343 -------------PQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPP 389
                        P L           R  +    SP+ P   PPD  P+      P  P
Sbjct: 408 ALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASP 467

Query: 390 P 390
           P
Sbjct: 468 P 468


>gi|51988887 SH3 domain containing ring finger 1 [Homo sapiens]
          Length = 888

 Score = 59.7 bits (143), Expect = 6e-09
 Identities = 50/185 (27%), Positives = 75/185 (40%), Gaps = 17/185 (9%)

Query: 296 STTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQIPLTGFV 355
           S+++ T++        ++    +Q H++   L       I  PPP  P  T   P   F 
Sbjct: 333 SSSNPTAAARISELSGLSCSAPSQVHISTTGL-------IVTPPPSSPVTTG--PSFTFP 383

Query: 356 ARVQENIADSPTPPPPPPPDDIP--MFDDSPPPPPPPPVDYEDEEAAVVQYNDPYADGDP 413
           + V    A     PP PPP  +   +   +PP               +    D  A   P
Sbjct: 384 SDVPYQAALGTLNPPLPPPPLLAATVLASTPPGATAAAAAAGMGPRPMAGSTDQIAHLRP 443

Query: 414 AWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVT--GLFPGN 471
              P  Y    VAIY YT  K+DEL   +G +  V ++  DGW++G     +  G+FPGN
Sbjct: 444 QTRPSVY----VAIYPYTPRKEDELELRKGEMFLVFERCQDGWFKGTSMHTSKIGVFPGN 499

Query: 472 YVESI 476
           YV  +
Sbjct: 500 YVAPV 504



 Score = 53.1 bits (126), Expect = 5e-07
 Identities = 71/316 (22%), Positives = 110/316 (34%), Gaps = 49/316 (15%)

Query: 191 TLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRE 250
           T+  +   +    V P  V N    SPA +G  H     AS    P     ++  +    
Sbjct: 592 TVAAHNQERPTAAVTPIQVQNAAGLSPASVGLSHHS--LASPQPAPLMPGSATHTAAISI 649

Query: 251 NSGSSSIGIPIAVPTPSPPTIGPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTP 310
           +  S+ +    A P  SP +I  A+  + P  +  T+   +     + SS         P
Sbjct: 650 SRASAPLACAAAAPLTSP-SITSASLEAEPSGRIVTVLPGLPTSPDSASSACGNSSATKP 708

Query: 311 SVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQENIADSPTPPP 370
              ++   +     G L   +  S    P   P  +P + +    A +    A  P  PP
Sbjct: 709 DKDSKKEKK-----GLLKLLSGASTKRKPRVSPPASPTLEVELGSAELPLQGAVGPELPP 763

Query: 371 P---------PPPDDIPMFD-------------------DSPPPPPPPPVDYEDEEAAVV 402
                     P   D P+                     DS  P  PPP         V+
Sbjct: 764 GGGHGRAGSCPVDGDGPVTTAVAGAALAQDAFHRKASSLDSAVPIAPPPRQACSSLGPVL 823

Query: 403 QYNDPYADGDPAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCN 462
             + P              E+   +  Y    + EL   EG I++V KK +DGW++G   
Sbjct: 824 NESRPVV-----------CERHRVVVSYPPQSEAELELKEGDIVFVHKKREDGWFKGTLQ 872

Query: 463 R--VTGLFPGNYVESI 476
           R   TGLFPG++VE+I
Sbjct: 873 RNGKTGLFPGSFVENI 888



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 19/51 (37%), Positives = 31/51 (60%)

Query: 426 AIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESI 476
           A+Y+Y   +  +L F +G II + ++ D+ WY G  N + G FP N+V+ I
Sbjct: 141 ALYNYEGKEPGDLKFSKGDIIILRRQVDENWYHGEVNGIHGFFPTNFVQII 191



 Score = 38.9 bits (89), Expect = 0.010
 Identities = 21/53 (39%), Positives = 33/53 (62%), Gaps = 4/53 (7%)

Query: 426 AIYDY-TKDKD---DELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVE 474
           A+YD+  KDK+   D L F +  ++ VI++ D+ W EG+     G+FP +YVE
Sbjct: 203 ALYDFEVKDKEADKDCLPFAKDDVLTVIRRVDENWAEGMLADKIGIFPISYVE 255


>gi|167234422 hematopoietic cell-specific Lyn substrate 1 [Homo
           sapiens]
          Length = 486

 Score = 59.7 bits (143), Expect = 6e-09
 Identities = 43/154 (27%), Positives = 64/154 (41%), Gaps = 37/154 (24%)

Query: 358 VQENIADSPTPPPPPPP--------DDIPMFDDSPPPPPPPPV----DYEDEEAAVVQYN 405
           +++ + +    PP  PP        ++ P+++  P P P P      DYED E       
Sbjct: 330 IRQTLPEDNEEPPALPPRTLEGLQVEEEPVYEAEPEPEPEPEPEPENDYEDVEEMDRHEQ 389

Query: 406 DPYADGD----------------------PAWAPKNYIE---KVVAIYDYTKDKDDELSF 440
           +   +GD                      PA A    +      VA+YDY  +  DELSF
Sbjct: 390 EDEPEGDYEEVLEPEDSSFSSALAGSSGCPAGAGAGAVALGISAVALYDYQGEGSDELSF 449

Query: 441 MEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVE 474
               +I  I+  D+GW+ G C+   GLFP NYV+
Sbjct: 450 DPDDVITDIEMVDEGWWRGRCHGHFGLFPANYVK 483


>gi|55956916 myosin IE [Homo sapiens]
          Length = 1108

 Score = 59.3 bits (142), Expect = 7e-09
 Identities = 63/248 (25%), Positives = 95/248 (38%), Gaps = 38/248 (15%)

Query: 241  GSSGGSGSRENSGSSSIGIPIAVPTPSPP----TIGPAAPGSAPGSQYGTMTRQISRHNS 296
            G     GSR+       G  +AV  PS      +IGP  P ++  ++  T   Q + ++S
Sbjct: 887  GPWSAGGSRQVQFHQGFG-DLAVLKPSNKVLQVSIGPGLPKNSRPTRRNTT--QNTGYSS 943

Query: 297  TTSSTS--------SGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQ 348
             T + +          GY +   +  Q+   PH  G    +Q S+  +   PP+P+   Q
Sbjct: 944  GTQNANYPVRAAPPPPGYHQNGVIRNQYVPYPHAPGSQRSNQKSLYTSMARPPLPR--QQ 1001

Query: 349  IPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYNDPY 408
               +  V++  E++ D    P              PPP    P                 
Sbjct: 1002 STSSDRVSQTPESL-DFLKVPDQGAAGVRRQTTSRPPPAGGRP----------------- 1043

Query: 409  ADGDPAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLF 468
                P   PK  + +  A+Y Y     DELSF    II +IK++  GW+ G      GLF
Sbjct: 1044 ---KPQPKPKPQVPQCKALYAYDAQDTDELSFNANDIIDIIKEDPSGWWTGRLRGKQGLF 1100

Query: 469  PGNYVESI 476
            P NYV  I
Sbjct: 1101 PNNYVTKI 1108


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 67/244 (27%), Positives = 99/244 (40%), Gaps = 36/244 (14%)

Query: 163 NQPARTGTLSRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGS 222
           + PAR+G  +R  P     PS P             K L+ ++PP V      +   LG 
Sbjct: 250 SSPARSGPSARGTPRAPAHPSQPKP-----------KGLQALRPPQVTPPRKDAAPALGP 298

Query: 223 QHS-----PGRTASL-NQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPS-PPTI---- 271
             S     P  +A+L +Q P T   +   S     +   +  +P+A P+PS PP++    
Sbjct: 299 LSSSPLATPSPSAALQSQAPPTLPATPHSSSL---TCQLATPLPLAPPSPSAPPSLQTLP 355

Query: 272 -GPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQ 330
             PA P S   +  G+ T Q + H+   S   S      P  T    A P +   PL + 
Sbjct: 356 SPPATPPSQATTSLGSPTLQ-ATHSFLPSPPLS------PLATPPPQAPPALALPPLQAP 408

Query: 331 NSISIAPPPPPMPQLTPQIPLTGFVARVQENIADSPTPP---PPPPPDDIPMFDDSPPPP 387
            S   +PP  P+   +PQ P    V  +Q   +  P+PP   P  PP   P+   + PP 
Sbjct: 409 PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPS 468

Query: 388 PPPP 391
             PP
Sbjct: 469 QAPP 472



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 67/260 (25%), Positives = 94/260 (36%), Gaps = 37/260 (14%)

Query: 169 GTLSRTNPPTQKPPSPPMSGR----GT-LGRNTPYKTLEPVKPPTVP-------NDYMTS 216
           G    T+ PT   PSP M+ R    GT +G   P  +  P  P   P       +++ T+
Sbjct: 159 GARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTT 218

Query: 217 PARLGSQHSPGRTASLNQRPRTHSGSSGGS--GSRENSGSSSIGIPIAVPTPS------- 267
                ++  P     L QRP + S SS  +   S   SG S+ G P A   PS       
Sbjct: 219 EPSPAARRRPSAGGGL-QRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGL 277

Query: 268 ----PPTIGP----AAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQ 319
               PP + P    AAP   P S     T   S    + +  +      + S+T Q +  
Sbjct: 278 QALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATP 337

Query: 320 PHVNGGPLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQENIADSP------TPPPPPP 373
             +      +  S+   P PP  P       L     +   +   SP      TPPP  P
Sbjct: 338 LPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAP 397

Query: 374 PD-DIPMFDDSPPPPPPPPV 392
           P   +P     P PP  PP+
Sbjct: 398 PALALPPLQAPPSPPASPPL 417



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 69/242 (28%), Positives = 97/242 (40%), Gaps = 42/242 (17%)

Query: 165 PARTGTLSRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQH 224
           P+ +  L    PPT   P+ P S   T    TP     P+ PP+      ++P  L +  
Sbjct: 307 PSPSAALQSQAPPTL--PATPHSSSLTCQLATPL----PLAPPSP-----SAPPSLQTLP 355

Query: 225 SPGRTASLNQRPRTHSGSSGGSGSRENSGS---SSIGIPIAVPTP-SPPTIG-------P 273
           SP  T      P + + +S GS + + + S   S    P+A P P +PP +        P
Sbjct: 356 SPPAT------PPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPP 409

Query: 274 AAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFS--AQPHVNGGPLY-SQ 330
           + P S P S   T + Q     +     +      +P V A FS  A P V+      SQ
Sbjct: 410 SPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQ 469

Query: 331 NSISIAPPPPPMPQLTPQIPLTGFVARVQENIADSPTPPPP-PPPDDIPMFDDSPPPPPP 389
              S+A PP  +P   P  P           ++ S TPPP  PPP   P    + PPP  
Sbjct: 470 APPSLAAPPLQVPPSPPASP----------PMSPSATPPPQAPPPLAAPPLQLAKPPPQA 519

Query: 390 PP 391
           PP
Sbjct: 520 PP 521



 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 72/307 (23%), Positives = 97/307 (31%), Gaps = 87/307 (28%)

Query: 167 RTGTLSRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSP 226
           R G +     P   P + P    GT  RN   +     +    P    TSP   G   SP
Sbjct: 61  RAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSP---GPVSSP 117

Query: 227 GRTASLNQRP-----------------------------------RTHSGSSGGSGS--- 248
           GR AS   RP                                   R  SG + G+ S   
Sbjct: 118 GR-ASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAM 176

Query: 249 --RENSGSSSIGIPIAVPT--PSPPTIGPAAPGSAPG---------------SQYGTMTR 289
             R  +  + +G+P   P+  P PPT GP    S+                 S  G + R
Sbjct: 177 ARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQR 236

Query: 290 QISRHNSTTSSTSSGGYRRTPSV-----TAQFSAQPHVNG-------------------- 324
             SR  S++++  S   R  PS           +QP   G                    
Sbjct: 237 PASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPAL 296

Query: 325 GPLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSP 384
           GPL S    + +P      Q  P +P T   + +   +A +P P  PP P   P     P
Sbjct: 297 GPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLA-TPLPLAPPSPSAPPSLQTLP 355

Query: 385 PPPPPPP 391
            PP  PP
Sbjct: 356 SPPATPP 362



 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 62/235 (26%), Positives = 81/235 (34%), Gaps = 37/235 (15%)

Query: 165 PARTGTLSRTNPPTQKP----PSPPMSGRGTLGRNTPYK-TLEPVK-PPTVPNDYMTSPA 218
           P    T S  +P  Q      PSPP+S   T     P    L P++ PP+ P     SP 
Sbjct: 361 PPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPL 420

Query: 219 RLGSQHSPGRTA-SLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPAAPG 277
              S  +P   A  L Q P +   S                 P+  P  SPP   P +P 
Sbjct: 421 ATPSPQAPNALAVHLLQAPFSPPPSP----------------PVQAPF-SPPASPPVSPS 463

Query: 278 SAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAP 337
           + P SQ       ++        +       +PS T    A P +   PL       +A 
Sbjct: 464 ATPPSQ---APPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPL------QLAK 514

Query: 338 PPPPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPPPPV 392
           PPP  P      PL    +      A  P   P  P   +PM   + PPP  PPV
Sbjct: 515 PPPQAPPALATPPLQALPSPP----ASFPGQAPFSPSASLPMSPLATPPPQAPPV 565



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 59/217 (27%), Positives = 77/217 (35%), Gaps = 38/217 (17%)

Query: 176 PPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQR 235
           PP Q PPSPP S         P  +     PP  P      P +L ++  P    +L   
Sbjct: 477 PPLQVPPSPPAS---------PPMSPSATPPPQAPPPLAAPPLQL-AKPPPQAPPALATP 526

Query: 236 PRTHSGSSGGS--GSRENSGSSSIGI-PIAVPTPSPPTIGPAAPGSAPGSQYGTMTRQIS 292
           P     S   S  G    S S+S+ + P+A P P  P +  A     P S   + T Q  
Sbjct: 527 PLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAP 586

Query: 293 RHNSTTS-STSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQIPL 351
           R   T    TS  G R T                       +++AP PPP P  +P   L
Sbjct: 587 RRPPTPGPDTSVSGPRLT-----------------------LALAPGPPPPPSRSPSSTL 623

Query: 352 TGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPP 388
           +G       + A S TP      D  P    +  PPP
Sbjct: 624 SGPDLAGHSSSATS-TPEELRGYDSGPEGGAAASPPP 659


>gi|150417989 cyclin K isoform 1 [Homo sapiens]
          Length = 580

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 67/237 (28%), Positives = 86/237 (36%), Gaps = 33/237 (13%)

Query: 177 PTQKPPSPPMSGRGTL-GRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQR 235
           P+ +P SP    R  +       K  EP  PP +P    T P    +   P R   L   
Sbjct: 323 PSPQPSSPRQVKRAVVVSPKEENKAAEP-PPPKIPKIETTHPPLPPAHPPPDRKPPL--- 378

Query: 236 PRTHSGSSGGSGSRENSGSSSIGIPIAV---PTPSPPTIGPAAPGSAPGSQYGTMTRQIS 292
                G +   G  + +    + IP      P   PP + P  P   P S Y T      
Sbjct: 379 -AAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPL-PHRPPPPPPSSYMTGM---- 432

Query: 293 RHNSTTSSTSSG-GYRRTPSVTA----QFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTP 347
              STTSS  SG GY+   S+       + A P   G P +      + PP PP P + P
Sbjct: 433 ---STTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPPPPVPP 489

Query: 348 QIPLTGFVARVQENIADSPTPPP------PPPPDDIPMFDDSPPPPPP----PPVDY 394
             P +     +       P PPP      PPPP  +P     PP PPP    PP  Y
Sbjct: 490 P-PASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPPASY 545



 Score = 39.7 bits (91), Expect = 0.006
 Identities = 63/297 (21%), Positives = 98/297 (32%), Gaps = 43/297 (14%)

Query: 140 PIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQKPPSPPMSGRGTLGRNTPYK 199
           P+D  VL+D+ H +  L ++     P  T    +  P  Q  P  P      + ++ P +
Sbjct: 243 PVD--VLEDICHQILDLYSQGKQQMPHHTPHQLQQPPSLQPTPQVPQ-----VQQSQPSQ 295

Query: 200 TLEPVKP----PTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSS 255
           + EP +P    P  P      PA+   + SP  ++     PR    +   S   EN  + 
Sbjct: 296 SSEPSQPQQKDPQQPAQQQ-QPAQQPKKPSPQPSS-----PRQVKRAVVVSPKEENKAAE 349

Query: 256 SIGIPIAVPTPSPPTIGPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQ 315
                   P P  P I    P   P          ++                 P V   
Sbjct: 350 P-------PPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIP 402

Query: 316 FSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQIPLT-------GFVARVQENIADSPT- 367
             A P     P++    +   PPPPP       +  T       G+ +       + P+ 
Sbjct: 403 PPAHP----APVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSY 458

Query: 368 ---PPPPPPPDDIP----MFDDSPPPPPPPPVDYEDEEAAVVQYNDPYADGDPAWAP 417
              PP   PP  +P    ++  +PPPPP PP        A+      Y    P + P
Sbjct: 459 GALPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNP 515



 Score = 37.0 bits (84), Expect = 0.040
 Identities = 28/95 (29%), Positives = 36/95 (37%), Gaps = 8/95 (8%)

Query: 326 PLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPP 385
           P   Q        P P P    Q+     V+  +EN A  P PP       IP  + + P
Sbjct: 310 PAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPK------IPKIETTHP 363

Query: 386 PPPP--PPVDYEDEEAAVVQYNDPYADGDPAWAPK 418
           P PP  PP D +   AA +   +P    D    PK
Sbjct: 364 PLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPK 398


>gi|224586855 sorbin and SH3 domain containing 2 isoform 8 [Homo
           sapiens]
          Length = 492

 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 34/96 (35%), Positives = 47/96 (48%), Gaps = 8/96 (8%)

Query: 386 PPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNYI---EKVVAIYDYTKDKDDELSFME 442
           P PP P  Y  +    +  N P     P +  +N     E   A+Y+YT   +DEL   E
Sbjct: 400 PDPPIPHSYSSDRIHSLSSNKPQR---PVFTHENIQGGGEPFQALYNYTPRNEDELELRE 456

Query: 443 GAIIYVIKKNDDGWYEGVCNRVT--GLFPGNYVESI 476
             +I V++K DDGW+ G   R    G FPGNYV+ +
Sbjct: 457 SDVIDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL 492



 Score = 52.8 bits (125), Expect = 7e-07
 Identities = 64/287 (22%), Positives = 97/287 (33%), Gaps = 31/287 (10%)

Query: 207 PTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTP 266
           P   N  + +P      H   +T +     ++HS +S  +       +SS   P  VP P
Sbjct: 40  PYTYNAGLYNPPYSAQSHPAAKTQTYRPLSKSHSDNSPNAFK----DASSPVPPPHVPPP 95

Query: 267 SPPTIGPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGP 326
            PP + P    S     +    R++      +   S   Y    S   Q     H     
Sbjct: 96  VPP-LRPRDRSSTEKHDWDPPDRKVDTRKFRSEPRSIFEYEPGKSSILQ-----HERPAS 149

Query: 327 LYS-------QNSISIAPPPPPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIP- 378
           LY        +  +S A       +     P  G        + D       P   D+P 
Sbjct: 150 LYQSSIDRSLERPMSSASMASDFRKRRKSEPAVG----PPRGLGDQSASRTSPGRVDLPG 205

Query: 379 -------MFDDSPPPPPPPPVDYEDEEAAVVQYNDP--YADGDPAWAPKNYIEKVVAIYD 429
                   F  S P  P    D E   +      D    A  +    P+       A+YD
Sbjct: 206 SSTTLTKSFTSSSPSSPSRAKDRESPRSYSSTLTDMGRSAPRERRGTPEKEKLPAKAVYD 265

Query: 430 YTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESI 476
           +      ELSF +G  +Y+++K D  WYEG  +   G+FP +YVE +
Sbjct: 266 FKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVEKL 312



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 81/368 (22%), Positives = 131/368 (35%), Gaps = 85/368 (23%)

Query: 156 LKAKHGNNQP-ARTGTLSRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYM 214
           L   H +N P A     S   PP   PP PP+  R     +T     +P         + 
Sbjct: 68  LSKSHSDNSPNAFKDASSPVPPPHVPPPVPPLRPRDR--SSTEKHDWDPPDRKVDTRKFR 125

Query: 215 TSPARLGSQHSPGRTASL-NQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGP 273
           + P  +  ++ PG+++ L ++RP +   SS          S+S+         S P +GP
Sbjct: 126 SEPRSI-FEYEPGKSSILQHERPASLYQSSIDRSLERPMSSASMASDFRKRRKSEPAVGP 184

Query: 274 -----------AAPGSA--PGSQYGTMTRQISRHNSTTSSTSSGGYRRTP-----SVTAQ 315
                       +PG    PGS   T+T+  +  +S+ SS S    R +P     ++T  
Sbjct: 185 PRGLGDQSASRTSPGRVDLPGSST-TLTKSFT--SSSPSSPSRAKDRESPRSYSSTLTDM 241

Query: 316 FSAQPHVNGGP-------------LYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQENI 362
             + P    G                +Q S  ++        +  +I    +       +
Sbjct: 242 GRSAPRERRGTPEKEKLPAKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRV 301

Query: 363 ADSP-------TPPPPPPPDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYNDPYADGDPAW 415
              P       TPP    P        + PPPP  P +                      
Sbjct: 302 GIFPISYVEKLTPPEKAQP--------ARPPPPAQPGE---------------------- 331

Query: 416 APKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGV---CNRVTGLFPGNY 472
                I + +A Y++  D + ELS  +G  + ++K+ D  WYEG     NR  G+FP +Y
Sbjct: 332 -----IGEAIAKYNFNADTNVELSLRKGDRVILLKRVDQNWYEGKIPGTNR-QGIFPVSY 385

Query: 473 VESIMHYT 480
           VE +   T
Sbjct: 386 VEVVKKNT 393


>gi|224586853 sorbin and SH3 domain containing 2 isoform 7 [Homo
            sapiens]
          Length = 1004

 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 34/96 (35%), Positives = 47/96 (48%), Gaps = 8/96 (8%)

Query: 386  PPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNYI---EKVVAIYDYTKDKDDELSFME 442
            P PP P  Y  +    +  N P     P +  +N     E   A+Y+YT   +DEL   E
Sbjct: 912  PDPPIPHSYSSDRIHSLSSNKPQR---PVFTHENIQGGGEPFQALYNYTPRNEDELELRE 968

Query: 443  GAIIYVIKKNDDGWYEGVCNRVT--GLFPGNYVESI 476
              +I V++K DDGW+ G   R    G FPGNYV+ +
Sbjct: 969  SDVIDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL 1004



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 21/51 (41%), Positives = 32/51 (62%)

Query: 426 AIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESI 476
           A+YD+      ELSF +G  +Y+++K D  WYEG  +   G+FP +YVE +
Sbjct: 774 AVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVEKL 824



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 25/71 (35%), Positives = 38/71 (53%), Gaps = 4/71 (5%)

Query: 413 PAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGV---CNRVTGLFP 469
           P  A    I + +A Y++  D + ELS  +G  + ++K+ D  WYEG     NR  G+FP
Sbjct: 836 PPPAQPGEIGEAIAKYNFNADTNVELSLRKGDRVILLKRVDQNWYEGKIPGTNR-QGIFP 894

Query: 470 GNYVESIMHYT 480
            +YVE +   T
Sbjct: 895 VSYVEVVKKNT 905



 Score = 33.5 bits (75), Expect = 0.44
 Identities = 38/165 (23%), Positives = 64/165 (38%), Gaps = 19/165 (11%)

Query: 156 LKAKHGNNQPARTGTLSRTNPPTQKPPS-PPMSGRGTLGRNTPYKTLEPVKPPTVPNDYM 214
           L   H +N P      S   PP   PP  PP+  R     +T     +P         + 
Sbjct: 53  LSKSHSDNSPNAFKDASSPVPPPHVPPPVPPLRPRDR--SSTEKHDWDPPDRKVDTRKFR 110

Query: 215 TSPARLGSQHSPGRTASL-NQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGP 273
           + P  +  ++ PG+++ L ++RP +   SS          S+S+         S P +GP
Sbjct: 111 SEPRSI-FEYEPGKSSILQHERPASLYQSSIDRSLERPMSSASMASDFRKRRKSEPAVGP 169

Query: 274 -----------AAPG--SAPGSQYGTMTRQISRHNSTTSSTSSGG 305
                       +PG    PGS   T+T+  +  + ++ S + GG
Sbjct: 170 PRGLGDQSASRTSPGRVDLPGSS-TTLTKSFTSSSPSSPSRAKGG 213


>gi|224586849 sorbin and SH3 domain containing 2 isoform 5 [Homo
           sapiens]
          Length = 661

 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 34/96 (35%), Positives = 47/96 (48%), Gaps = 8/96 (8%)

Query: 386 PPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNYI---EKVVAIYDYTKDKDDELSFME 442
           P PP P  Y  +    +  N P     P +  +N     E   A+Y+YT   +DEL   E
Sbjct: 569 PDPPIPHSYSSDRIHSLSSNKPQR---PVFTHENIQGGGEPFQALYNYTPRNEDELELRE 625

Query: 443 GAIIYVIKKNDDGWYEGVCNRVT--GLFPGNYVESI 476
             +I V++K DDGW+ G   R    G FPGNYV+ +
Sbjct: 626 SDVIDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL 661



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 21/51 (41%), Positives = 32/51 (62%)

Query: 426 AIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESI 476
           A+YD+      ELSF +G  +Y+++K D  WYEG  +   G+FP +YVE +
Sbjct: 431 AVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVEKL 481



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 25/71 (35%), Positives = 38/71 (53%), Gaps = 4/71 (5%)

Query: 413 PAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGV---CNRVTGLFP 469
           P  A    I + +A Y++  D + ELS  +G  + ++K+ D  WYEG     NR  G+FP
Sbjct: 493 PPPAQPGEIGEAIAKYNFNADTNVELSLRKGDRVILLKRVDQNWYEGKIPGTNR-QGIFP 551

Query: 470 GNYVESIMHYT 480
            +YVE +   T
Sbjct: 552 VSYVEVVKKNT 562


>gi|224586844 sorbin and SH3 domain containing 2 isoform 3 [Homo
           sapiens]
          Length = 644

 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 34/96 (35%), Positives = 47/96 (48%), Gaps = 8/96 (8%)

Query: 386 PPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNYI---EKVVAIYDYTKDKDDELSFME 442
           P PP P  Y  +    +  N P     P +  +N     E   A+Y+YT   +DEL   E
Sbjct: 552 PDPPIPHSYSSDRIHSLSSNKPQR---PVFTHENIQGGGEPFQALYNYTPRNEDELELRE 608

Query: 443 GAIIYVIKKNDDGWYEGVCNRVT--GLFPGNYVESI 476
             +I V++K DDGW+ G   R    G FPGNYV+ +
Sbjct: 609 SDVIDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL 644



 Score = 53.1 bits (126), Expect = 5e-07
 Identities = 67/298 (22%), Positives = 101/298 (33%), Gaps = 36/298 (12%)

Query: 196 TPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSS 255
           T +K +  V  P + N     P      H   +T +     ++HS +S  +       +S
Sbjct: 186 TMFKQIHMVHKPGLYN-----PPYSAQSHPAAKTQTYRPLSKSHSDNSPNAFK----DAS 236

Query: 256 SIGIPIAVPTPSPPTIGPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQ 315
           S   P  VP P PP + P    S     +    R++      +   S   Y    S   Q
Sbjct: 237 SPVPPPHVPPPVPP-LRPRDRSSTEKHDWDPPDRKVDTRKFRSEPRSIFEYEPGKSSILQ 295

Query: 316 FSAQPHVNGGPLYS-------QNSISIAPPPPPMPQLTPQIPLTGFVARVQENIADSPTP 368
                H     LY        +  +S A       +     P  G        + D    
Sbjct: 296 -----HERPASLYQSSIDRSLERPMSSASMASDFRKRRKSEPAVG----PPRGLGDQSAS 346

Query: 369 PPPPPPDDIP--------MFDDSPPPPPPPPVDYEDEEAAVVQYNDP--YADGDPAWAPK 418
              P   D+P         F  S P  P    D E   +      D    A  +    P+
Sbjct: 347 RTSPGRVDLPGSSTTLTKSFTSSSPSSPSRAKDRESPRSYSSTLTDMGRSAPRERRGTPE 406

Query: 419 NYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESI 476
                  A+YD+      ELSF +G  +Y+++K D  WYEG  +   G+FP +YVE +
Sbjct: 407 KEKLPAKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVEKL 464



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 81/368 (22%), Positives = 131/368 (35%), Gaps = 85/368 (23%)

Query: 156 LKAKHGNNQP-ARTGTLSRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYM 214
           L   H +N P A     S   PP   PP PP+  R     +T     +P         + 
Sbjct: 220 LSKSHSDNSPNAFKDASSPVPPPHVPPPVPPLRPRDR--SSTEKHDWDPPDRKVDTRKFR 277

Query: 215 TSPARLGSQHSPGRTASL-NQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGP 273
           + P  +  ++ PG+++ L ++RP +   SS          S+S+         S P +GP
Sbjct: 278 SEPRSI-FEYEPGKSSILQHERPASLYQSSIDRSLERPMSSASMASDFRKRRKSEPAVGP 336

Query: 274 -----------AAPGSA--PGSQYGTMTRQISRHNSTTSSTSSGGYRRTP-----SVTAQ 315
                       +PG    PGS   T+T+  +  +S+ SS S    R +P     ++T  
Sbjct: 337 PRGLGDQSASRTSPGRVDLPGSST-TLTKSFT--SSSPSSPSRAKDRESPRSYSSTLTDM 393

Query: 316 FSAQPHVNGGP-------------LYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQENI 362
             + P    G                +Q S  ++        +  +I    +       +
Sbjct: 394 GRSAPRERRGTPEKEKLPAKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRV 453

Query: 363 ADSP-------TPPPPPPPDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYNDPYADGDPAW 415
              P       TPP    P        + PPPP  P +                      
Sbjct: 454 GIFPISYVEKLTPPEKAQP--------ARPPPPAQPGE---------------------- 483

Query: 416 APKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGV---CNRVTGLFPGNY 472
                I + +A Y++  D + ELS  +G  + ++K+ D  WYEG     NR  G+FP +Y
Sbjct: 484 -----IGEAIAKYNFNADTNVELSLRKGDRVILLKRVDQNWYEGKIPGTNR-QGIFPVSY 537

Query: 473 VESIMHYT 480
           VE +   T
Sbjct: 538 VEVVKKNT 545


>gi|203098098 shroom family member 3 protein [Homo sapiens]
          Length = 1996

 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 66/266 (24%), Positives = 97/266 (36%), Gaps = 40/266 (15%)

Query: 169  GTLSRTNPPTQKP-PSPPMSGRGTLGRNTPYKTLEPVKPP---TVPNDYMTSPARLGSQH 224
            GTL      ++ P P PP++G   L  +T    L P+  P    +P+ Y +   + G Q 
Sbjct: 1318 GTLDHQRQASRTPCPRPPLAGTQGLVTDTRAAPLTPIGTPLPSAIPSGYCSQDGQTGRQP 1377

Query: 225  SPGRTASLNQRPRTHS-----GSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPAAPGSA 279
             P  T ++  R   H+     G  G  G     G    G    V  P  P      P S 
Sbjct: 1378 LPPYTPAMMHRSNGHTLTQPPGPRGCEGDGPEHGVEE-GTRKRVSLPQWP------PPSR 1430

Query: 280  PGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFS-AQPHVNGGPLYSQNSISIA-- 336
                +      +   +S     +   Y++  S+ +  S + P    G   +   IS+   
Sbjct: 1431 AKWAHAAREDSLPEESSAPDFANLKHYQKQQSLPSLCSTSDPDTPLGAPSTPGRISLRIS 1490

Query: 337  -----PPPPPMPQLTPQIPLTGFVARVQENIADSPT------PPPPPPPDDIPMF--DDS 383
                   PPP      ++    FV         SPT      PPPPPP  + P++  DD 
Sbjct: 1491 ESVLRDSPPPHEDYEDEV----FVRDPHPKATSSPTFEPLPPPPPPPPSQETPVYSMDDF 1546

Query: 384  PPPPP----PPPVDYEDEEAAVVQYN 405
            PPPPP       +D ED E     +N
Sbjct: 1547 PPPPPHTVCEAQLDSEDPEGPRPSFN 1572


>gi|10947118 sorbin and SH3 domain containing 2 isoform 2 [Homo
            sapiens]
          Length = 1100

 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 34/96 (35%), Positives = 47/96 (48%), Gaps = 8/96 (8%)

Query: 386  PPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNYI---EKVVAIYDYTKDKDDELSFME 442
            P PP P  Y  +    +  N P     P +  +N     E   A+Y+YT   +DEL   E
Sbjct: 1008 PDPPIPHSYSSDRIHSLSSNKPQR---PVFTHENIQGGGEPFQALYNYTPRNEDELELRE 1064

Query: 443  GAIIYVIKKNDDGWYEGVCNRVT--GLFPGNYVESI 476
              +I V++K DDGW+ G   R    G FPGNYV+ +
Sbjct: 1065 SDVIDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL 1100



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 21/51 (41%), Positives = 32/51 (62%)

Query: 426 AIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESI 476
           A+YD+      ELSF +G  +Y+++K D  WYEG  +   G+FP +YVE +
Sbjct: 870 AVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVEKL 920



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 25/71 (35%), Positives = 38/71 (53%), Gaps = 4/71 (5%)

Query: 413  PAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGV---CNRVTGLFP 469
            P  A    I + +A Y++  D + ELS  +G  + ++K+ D  WYEG     NR  G+FP
Sbjct: 932  PPPAQPGEIGEAIAKYNFNADTNVELSLRKGDRVILLKRVDQNWYEGKIPGTNR-QGIFP 990

Query: 470  GNYVESIMHYT 480
             +YVE +   T
Sbjct: 991  VSYVEVVKKNT 1001



 Score = 33.5 bits (75), Expect = 0.44
 Identities = 38/165 (23%), Positives = 64/165 (38%), Gaps = 19/165 (11%)

Query: 156 LKAKHGNNQPARTGTLSRTNPPTQKPPS-PPMSGRGTLGRNTPYKTLEPVKPPTVPNDYM 214
           L   H +N P      S   PP   PP  PP+  R     +T     +P         + 
Sbjct: 149 LSKSHSDNSPNAFKDASSPVPPPHVPPPVPPLRPRDR--SSTEKHDWDPPDRKVDTRKFR 206

Query: 215 TSPARLGSQHSPGRTASL-NQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGP 273
           + P  +  ++ PG+++ L ++RP +   SS          S+S+         S P +GP
Sbjct: 207 SEPRSI-FEYEPGKSSILQHERPASLYQSSIDRSLERPMSSASMASDFRKRRKSEPAVGP 265

Query: 274 -----------AAPG--SAPGSQYGTMTRQISRHNSTTSSTSSGG 305
                       +PG    PGS   T+T+  +  + ++ S + GG
Sbjct: 266 PRGLGDQSASRTSPGRVDLPGSS-TTLTKSFTSSSPSSPSRAKGG 309


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.130    0.387 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,158,237
Number of Sequences: 37866
Number of extensions: 1733239
Number of successful extensions: 32159
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 640
Number of HSP's successfully gapped in prelim test: 1164
Number of HSP's that attempted gapping in prelim test: 12382
Number of HSP's gapped (non-prelim): 10394
length of query: 481
length of database: 18,247,518
effective HSP length: 106
effective length of query: 375
effective length of database: 14,233,722
effective search space: 5337645750
effective search space used: 5337645750
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press