Guide to the Human Genome
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Search of human proteins with 13569922

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|13569922 NUAK family, SNF1-like kinase, 2 [Homo sapiens]
         (628 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|13569922 NUAK family, SNF1-like kinase, 2 [Homo sapiens]          1275   0.0  
gi|7662170 AMPK-related protein kinase 5 [Homo sapiens]               638   0.0  
gi|33636756 MAP/microtubule affinity-regulating kinase 4 [Homo s...   268   1e-71
gi|193083129 MAP/microtubule affinity-regulating kinase 3 isofor...   256   3e-68
gi|193083127 MAP/microtubule affinity-regulating kinase 3 isofor...   256   3e-68
gi|193083125 MAP/microtubule affinity-regulating kinase 3 isofor...   256   3e-68
gi|46852166 MAP/microtubule affinity-regulating kinase 3 isoform...   256   3e-68
gi|254028240 MAP/microtubule affinity-regulating kinase 2 isofor...   253   4e-67
gi|254028237 MAP/microtubule affinity-regulating kinase 2 isofor...   253   4e-67
gi|254028234 MAP/microtubule affinity-regulating kinase 2 isofor...   253   4e-67
gi|254028232 MAP/microtubule affinity-regulating kinase 2 isofor...   253   4e-67
gi|86990441 MAP/microtubule affinity-regulating kinase 2 isoform...   253   4e-67
gi|153791472 MAP/microtubule affinity-regulating kinase 1 [Homo ...   249   4e-66
gi|94557301 protein kinase, AMP-activated, alpha 1 catalytic sub...   244   2e-64
gi|38569491 serine/threonine-protein kinase QSK [Homo sapiens]        241   1e-63
gi|116256471 SNF1-like kinase [Homo sapiens]                          239   7e-63
gi|46877068 AMP-activated protein kinase alpha 2 catalytic subun...   236   4e-62
gi|94557299 protein kinase, AMP-activated, alpha 1 catalytic sub...   236   6e-62
gi|38569460 SNF1-like kinase 2 [Homo sapiens]                         234   2e-61
gi|24308326 BR serine/threonine kinase 1 [Homo sapiens]               221   2e-57
gi|116089335 BR serine/threonine kinase 2 [Homo sapiens]              218   1e-56
gi|7661974 maternal embryonic leucine zipper kinase [Homo sapiens]    197   3e-50
gi|23503303 serine/threonine-protein kinase NIM1 [Homo sapiens]       195   9e-50
gi|156105707 SNF related kinase [Homo sapiens]                        186   4e-47
gi|156105705 SNF related kinase [Homo sapiens]                        186   4e-47
gi|4885549 AKT3 kinase isoform 1 [Homo sapiens]                       173   5e-43
gi|32307163 AKT3 kinase isoform 2 [Homo sapiens]                      173   5e-43
gi|89363047 death-associated protein kinase 1 [Homo sapiens]          172   8e-43
gi|14042947 testis-specific serine kinase 1 [Homo sapiens]            172   1e-42
gi|4557511 death-associated protein kinase 3 [Homo sapiens]           172   1e-42

>gi|13569922 NUAK family, SNF1-like kinase, 2 [Homo sapiens]
          Length = 628

 Score = 1275 bits (3300), Expect = 0.0
 Identities = 628/628 (100%), Positives = 628/628 (100%)

Query: 1   MESLVFARRSGPTPSAAELARPLAEGLIKSPKPLMKKQAVKRHHHKHNLRHRYEFLETLG 60
           MESLVFARRSGPTPSAAELARPLAEGLIKSPKPLMKKQAVKRHHHKHNLRHRYEFLETLG
Sbjct: 1   MESLVFARRSGPTPSAAELARPLAEGLIKSPKPLMKKQAVKRHHHKHNLRHRYEFLETLG 60

Query: 61  KGTYGKVKKARESSGRLVAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHPHIIAIHEVFE 120
           KGTYGKVKKARESSGRLVAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHPHIIAIHEVFE
Sbjct: 61  KGTYGKVKKARESSGRLVAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHPHIIAIHEVFE 120

Query: 121 NSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCHQNRVVHRDLKLEN 180
           NSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCHQNRVVHRDLKLEN
Sbjct: 121 NSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCHQNRVVHRDLKLEN 180

Query: 181 ILLDANGNIKIADFGLSNLYHQGKFLQTFCGSPLYASPEIVNGKPYTGPEVDSWSLGVLL 240
           ILLDANGNIKIADFGLSNLYHQGKFLQTFCGSPLYASPEIVNGKPYTGPEVDSWSLGVLL
Sbjct: 181 ILLDANGNIKIADFGLSNLYHQGKFLQTFCGSPLYASPEIVNGKPYTGPEVDSWSLGVLL 240

Query: 241 YILVHGTMPFDGHDHKILVKQISNGAYREPPKPSDACGLIRWLLMVNPTRRATLEDVASH 300
           YILVHGTMPFDGHDHKILVKQISNGAYREPPKPSDACGLIRWLLMVNPTRRATLEDVASH
Sbjct: 241 YILVHGTMPFDGHDHKILVKQISNGAYREPPKPSDACGLIRWLLMVNPTRRATLEDVASH 300

Query: 301 WWVNWGYATRVGEQEAPHEGGHPGSDSARASMADWLRRSSRPLLENGAKVCSFFKQHAPG 360
           WWVNWGYATRVGEQEAPHEGGHPGSDSARASMADWLRRSSRPLLENGAKVCSFFKQHAPG
Sbjct: 301 WWVNWGYATRVGEQEAPHEGGHPGSDSARASMADWLRRSSRPLLENGAKVCSFFKQHAPG 360

Query: 361 GGSTTPGLERQHSLKKSRKENDMAQSLHSDTADDTAHRPGKSNLKLPKGILKKKVSASAE 420
           GGSTTPGLERQHSLKKSRKENDMAQSLHSDTADDTAHRPGKSNLKLPKGILKKKVSASAE
Sbjct: 361 GGSTTPGLERQHSLKKSRKENDMAQSLHSDTADDTAHRPGKSNLKLPKGILKKKVSASAE 420

Query: 421 GVQEDPPELSPIPASPGQAAPLLPKKGILKKPRQRESGYYSSPEPSESGELLDAGDVFVS 480
           GVQEDPPELSPIPASPGQAAPLLPKKGILKKPRQRESGYYSSPEPSESGELLDAGDVFVS
Sbjct: 421 GVQEDPPELSPIPASPGQAAPLLPKKGILKKPRQRESGYYSSPEPSESGELLDAGDVFVS 480

Query: 481 GDPKEQKPPQASGLLLHRKGILKLNGKFSQTALELAAPTTFGSLDELAPPRPLARASRPS 540
           GDPKEQKPPQASGLLLHRKGILKLNGKFSQTALELAAPTTFGSLDELAPPRPLARASRPS
Sbjct: 481 GDPKEQKPPQASGLLLHRKGILKLNGKFSQTALELAAPTTFGSLDELAPPRPLARASRPS 540

Query: 541 GAVSEDSILSSESFDQLDLPERLPEPPLRGCVSVDNLTGLEEPPSEGPGSCLRRWRQDPL 600
           GAVSEDSILSSESFDQLDLPERLPEPPLRGCVSVDNLTGLEEPPSEGPGSCLRRWRQDPL
Sbjct: 541 GAVSEDSILSSESFDQLDLPERLPEPPLRGCVSVDNLTGLEEPPSEGPGSCLRRWRQDPL 600

Query: 601 GDSCFSLTDCQEVTATYRQALRVCSKLT 628
           GDSCFSLTDCQEVTATYRQALRVCSKLT
Sbjct: 601 GDSCFSLTDCQEVTATYRQALRVCSKLT 628


>gi|7662170 AMPK-related protein kinase 5 [Homo sapiens]
          Length = 661

 Score =  638 bits (1646), Expect = 0.0
 Identities = 369/641 (57%), Positives = 433/641 (67%), Gaps = 67/641 (10%)

Query: 36  KKQAVKRHHHKHNLRHRYEFLETLGKGTYGKVKKARES-SGRLVAIKSIRKDKIKDEQDL 94
           K   VKRHHHKHNL+HRYE  ETLGKGTYGKVK+A E  SGR+VAIKSIRKDKIKDEQD+
Sbjct: 38  KPHGVKRHHHKHNLKHRYELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDEQDM 97

Query: 95  MHIRREIEIMSSLNHPHIIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARH 154
           +HIRREIEIMSSLNHPHII+I+EVFEN  KIVI+MEYAS+G+LYDYISER++LSERE RH
Sbjct: 98  VHIRREIEIMSSLNHPHIISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSERETRH 157

Query: 155 FFRQIVSAVHYCHQNRVVHRDLKLENILLDANGNIKIADFGLSNLYHQGKFLQTFCGSPL 214
           FFRQIVSAVHYCH+N VVHRDLKLENILLD N NIKIADFGLSNLY + KFLQTFCGSPL
Sbjct: 158 FFRQIVSAVHYCHKNGVVHRDLKLENILLDDNCNIKIADFGLSNLYQKDKFLQTFCGSPL 217

Query: 215 YASPEIVNGKPYTGPEVDSWSLGVLLYILVHGTMPFDGHDHKILVKQISNGAYREPPKPS 274
           YASPEIVNG+PY GPEVDSW+LGVLLY LV+GTMPFDG DHK L++QIS+G YREP +PS
Sbjct: 218 YASPEIVNGRPYRGPEVDSWALGVLLYTLVYGTMPFDGFDHKNLIRQISSGEYREPTQPS 277

Query: 275 DACGLIRWLLMVNPTRRATLEDVASHWWVNWGYATRVGEQEAPHEGGHPGSDSARASMAD 334
           DA GLIRW+LMVNP RRAT+ED+A+HWWVNWGY + V + +A H+   P      A + D
Sbjct: 278 DARGLIRWMLMVNPDRRATIEDIANHWWVNWGYKSSVCDCDALHDSESP----LLARIID 333

Query: 335 WLRRSSRPLLENGAKVCSFFKQHAPGGGSTTPGLERQHSLKKSRKENDMAQSLHSDTADD 394
           W  RS+    +  AK+    K       ++   LERQ SLKKS+KEND AQS      D 
Sbjct: 334 WHHRSTGLQADTEAKMKGLAKP-----TTSEVMLERQRSLKKSKKENDFAQS----GQDA 384

Query: 395 TAHRPGKSNLKLPKGILKKKVSAS--------AEGV----------------------QE 424
               P K + K PKGILKK+ ++          EGV                        
Sbjct: 385 VPESPSKLSSKRPKGILKKRSNSEHRSHSTGFIEGVVGPALPSTFKMEQDLCRTGVLLPS 444

Query: 425 DPPELSPIPASPGQAAPLLPKKGILKKPRQRESGYYSSPEPSESGELLDAGDVFVSGDPK 484
            P    P   SP Q+A  +PKKGILKK +QRESGYYSSPE SES ELLD+ DV  S  P 
Sbjct: 445 SPEAEVPGKLSPKQSA-TMPKKGILKKTQQRESGYYSSPERSESSELLDSNDVMGSSIPS 503

Query: 485 EQKPPQA----SGLLLHRKGILKLNGKFSQTALE--LAAP--TTFGSLDEL-APPRPLAR 535
              P  A      L   RKGILK + K+S   ++  L +P   T  SL E   P   L+R
Sbjct: 504 PSPPDPARVTSHSLSCRRKGILKHSSKYSAGTMDPALVSPEMPTLESLSEPGVPAEGLSR 563

Query: 536 A-SRPSGAVSEDSILSSESFDQLDLPERLP-EPPLRGCVSVDN------LTGLEEPPSEG 587
           + SRPS  +S+DS+LSS+SFD LDL E  P    +R CVS +N        GL+  P   
Sbjct: 564 SYSRPSSVISDDSVLSSDSFDLLDLQENRPARQRIRSCVSAENFLQIQDFEGLQNRPRP- 622

Query: 588 PGSCLRRWRQDPLGDSCFS-LTDCQEVTATYRQALRVCSKL 627
               L+R+R + L DS FS LTD  +VT  Y+QAL +CSKL
Sbjct: 623 --QYLKRYR-NRLADSSFSLLTDMDDVTQVYKQALEICSKL 660


>gi|33636756 MAP/microtubule affinity-regulating kinase 4 [Homo
           sapiens]
          Length = 688

 Score =  268 bits (685), Expect = 1e-71
 Identities = 138/268 (51%), Positives = 179/268 (66%), Gaps = 6/268 (2%)

Query: 53  YEFLETLGKGTYGKVKKARES-SGRLVAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHPH 111
           Y  L T+GKG + KVK AR   +GR VAIK I K ++ +   L  + RE+ IM  LNHP+
Sbjct: 59  YRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQL-NPSSLQKLFREVRIMKGLNHPN 117

Query: 112 IIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCHQNRV 171
           I+ + EV E    + +VMEYAS G+++DY+    ++ E+EAR  FRQIVSAVHYCHQ  +
Sbjct: 118 IVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNI 177

Query: 172 VHRDLKLENILLDANGNIKIADFGLSNLYHQGKFLQTFCGSPLYASPEIVNGKPYTGPEV 231
           VHRDLK EN+LLDA  NIKIADFG SN +  G  L TFCGSP YA+PE+  GK Y GPEV
Sbjct: 178 VHRDLKAENLLLDAEANIKIADFGFSNEFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEV 237

Query: 232 DSWSLGVLLYILVHGTMPFDGHDHKILVKQISNGAYREPPKPSDAC-GLIRWLLMVNPTR 290
           D WSLGV+LY LV G++PFDGH+ K L +++  G YR P   S  C  ++R  L++NP +
Sbjct: 238 DIWSLGVILYTLVSGSLPFDGHNLKELRERVLRGKYRVPFYMSTDCESILRRFLVLNPAK 297

Query: 291 RATLEDVASHWWVNWGYATRVGEQEAPH 318
           R TLE +    W+N GY    GE+  P+
Sbjct: 298 RCTLEQIMKDKWINIGYE---GEELKPY 322


>gi|193083129 MAP/microtubule affinity-regulating kinase 3 isoform d
           [Homo sapiens]
          Length = 713

 Score =  256 bits (655), Expect = 3e-68
 Identities = 132/257 (51%), Positives = 175/257 (68%), Gaps = 3/257 (1%)

Query: 53  YEFLETLGKGTYGKVKKARES-SGRLVAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHPH 111
           Y  L+T+GKG + KVK AR   +GR VAIK I K ++ +   L  + RE+ IM  LNHP+
Sbjct: 56  YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQL-NPTSLQKLFREVRIMKILNHPN 114

Query: 112 IIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCHQNRV 171
           I+ + EV E    + ++MEYAS G+++DY+    ++ E+EAR  FRQIVSAV YCHQ R+
Sbjct: 115 IVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRI 174

Query: 172 VHRDLKLENILLDANGNIKIADFGLSNLYHQGKFLQTFCGSPLYASPEIVNGKPYTGPEV 231
           VHRDLK EN+LLDA+ NIKIADFG SN +  G  L TFCGSP YA+PE+  GK Y GPEV
Sbjct: 175 VHRDLKAENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEV 234

Query: 232 DSWSLGVLLYILVHGTMPFDGHDHKILVKQISNGAYREPPKPSDAC-GLIRWLLMVNPTR 290
           D WSLGV+LY LV G++PFDG + K L +++  G YR P   S  C  L++  L++NP +
Sbjct: 235 DVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIK 294

Query: 291 RATLEDVASHWWVNWGY 307
           R TLE +    W+N G+
Sbjct: 295 RGTLEQIMKDRWINAGH 311


>gi|193083127 MAP/microtubule affinity-regulating kinase 3 isoform b
           [Homo sapiens]
          Length = 744

 Score =  256 bits (655), Expect = 3e-68
 Identities = 132/257 (51%), Positives = 175/257 (68%), Gaps = 3/257 (1%)

Query: 53  YEFLETLGKGTYGKVKKARES-SGRLVAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHPH 111
           Y  L+T+GKG + KVK AR   +GR VAIK I K ++ +   L  + RE+ IM  LNHP+
Sbjct: 56  YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQL-NPTSLQKLFREVRIMKILNHPN 114

Query: 112 IIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCHQNRV 171
           I+ + EV E    + ++MEYAS G+++DY+    ++ E+EAR  FRQIVSAV YCHQ R+
Sbjct: 115 IVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRI 174

Query: 172 VHRDLKLENILLDANGNIKIADFGLSNLYHQGKFLQTFCGSPLYASPEIVNGKPYTGPEV 231
           VHRDLK EN+LLDA+ NIKIADFG SN +  G  L TFCGSP YA+PE+  GK Y GPEV
Sbjct: 175 VHRDLKAENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEV 234

Query: 232 DSWSLGVLLYILVHGTMPFDGHDHKILVKQISNGAYREPPKPSDAC-GLIRWLLMVNPTR 290
           D WSLGV+LY LV G++PFDG + K L +++  G YR P   S  C  L++  L++NP +
Sbjct: 235 DVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIK 294

Query: 291 RATLEDVASHWWVNWGY 307
           R TLE +    W+N G+
Sbjct: 295 RGTLEQIMKDRWINAGH 311


>gi|193083125 MAP/microtubule affinity-regulating kinase 3 isoform a
           [Homo sapiens]
          Length = 753

 Score =  256 bits (655), Expect = 3e-68
 Identities = 132/257 (51%), Positives = 175/257 (68%), Gaps = 3/257 (1%)

Query: 53  YEFLETLGKGTYGKVKKARES-SGRLVAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHPH 111
           Y  L+T+GKG + KVK AR   +GR VAIK I K ++ +   L  + RE+ IM  LNHP+
Sbjct: 56  YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQL-NPTSLQKLFREVRIMKILNHPN 114

Query: 112 IIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCHQNRV 171
           I+ + EV E    + ++MEYAS G+++DY+    ++ E+EAR  FRQIVSAV YCHQ R+
Sbjct: 115 IVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRI 174

Query: 172 VHRDLKLENILLDANGNIKIADFGLSNLYHQGKFLQTFCGSPLYASPEIVNGKPYTGPEV 231
           VHRDLK EN+LLDA+ NIKIADFG SN +  G  L TFCGSP YA+PE+  GK Y GPEV
Sbjct: 175 VHRDLKAENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEV 234

Query: 232 DSWSLGVLLYILVHGTMPFDGHDHKILVKQISNGAYREPPKPSDAC-GLIRWLLMVNPTR 290
           D WSLGV+LY LV G++PFDG + K L +++  G YR P   S  C  L++  L++NP +
Sbjct: 235 DVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIK 294

Query: 291 RATLEDVASHWWVNWGY 307
           R TLE +    W+N G+
Sbjct: 295 RGTLEQIMKDRWINAGH 311


>gi|46852166 MAP/microtubule affinity-regulating kinase 3 isoform c
           [Homo sapiens]
          Length = 729

 Score =  256 bits (655), Expect = 3e-68
 Identities = 132/257 (51%), Positives = 175/257 (68%), Gaps = 3/257 (1%)

Query: 53  YEFLETLGKGTYGKVKKARES-SGRLVAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHPH 111
           Y  L+T+GKG + KVK AR   +GR VAIK I K ++ +   L  + RE+ IM  LNHP+
Sbjct: 56  YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQL-NPTSLQKLFREVRIMKILNHPN 114

Query: 112 IIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCHQNRV 171
           I+ + EV E    + ++MEYAS G+++DY+    ++ E+EAR  FRQIVSAV YCHQ R+
Sbjct: 115 IVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRI 174

Query: 172 VHRDLKLENILLDANGNIKIADFGLSNLYHQGKFLQTFCGSPLYASPEIVNGKPYTGPEV 231
           VHRDLK EN+LLDA+ NIKIADFG SN +  G  L TFCGSP YA+PE+  GK Y GPEV
Sbjct: 175 VHRDLKAENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEV 234

Query: 232 DSWSLGVLLYILVHGTMPFDGHDHKILVKQISNGAYREPPKPSDAC-GLIRWLLMVNPTR 290
           D WSLGV+LY LV G++PFDG + K L +++  G YR P   S  C  L++  L++NP +
Sbjct: 235 DVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIK 294

Query: 291 RATLEDVASHWWVNWGY 307
           R TLE +    W+N G+
Sbjct: 295 RGTLEQIMKDRWINAGH 311


>gi|254028240 MAP/microtubule affinity-regulating kinase 2 isoform f
           [Homo sapiens]
          Length = 709

 Score =  253 bits (646), Expect = 4e-67
 Identities = 130/257 (50%), Positives = 175/257 (68%), Gaps = 3/257 (1%)

Query: 53  YEFLETLGKGTYGKVKKARES-SGRLVAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHPH 111
           Y  L+T+GKG + KVK AR   +G+ VA+K I K ++ +   L  + RE+ IM  LNHP+
Sbjct: 53  YRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQL-NSSSLQKLFREVRIMKVLNHPN 111

Query: 112 IIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCHQNRV 171
           I+ + EV E    + +VMEYAS G+++DY+    ++ E+EAR  FRQIVSAV YCHQ  +
Sbjct: 112 IVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFI 171

Query: 172 VHRDLKLENILLDANGNIKIADFGLSNLYHQGKFLQTFCGSPLYASPEIVNGKPYTGPEV 231
           VHRDLK EN+LLDA+ NIKIADFG SN +  G  L TFCGSP YA+PE+  GK Y GPEV
Sbjct: 172 VHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEV 231

Query: 232 DSWSLGVLLYILVHGTMPFDGHDHKILVKQISNGAYREPPKPSDAC-GLIRWLLMVNPTR 290
           D WSLGV+LY LV G++PFDG + K L +++  G YR P   S  C  L++  L++NP++
Sbjct: 232 DVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSK 291

Query: 291 RATLEDVASHWWVNWGY 307
           R TLE +    W+N G+
Sbjct: 292 RGTLEQIMKDRWMNVGH 308


>gi|254028237 MAP/microtubule affinity-regulating kinase 2 isoform e
           [Homo sapiens]
          Length = 719

 Score =  253 bits (646), Expect = 4e-67
 Identities = 130/257 (50%), Positives = 175/257 (68%), Gaps = 3/257 (1%)

Query: 53  YEFLETLGKGTYGKVKKARES-SGRLVAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHPH 111
           Y  L+T+GKG + KVK AR   +G+ VA+K I K ++ +   L  + RE+ IM  LNHP+
Sbjct: 53  YRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQL-NSSSLQKLFREVRIMKVLNHPN 111

Query: 112 IIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCHQNRV 171
           I+ + EV E    + +VMEYAS G+++DY+    ++ E+EAR  FRQIVSAV YCHQ  +
Sbjct: 112 IVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFI 171

Query: 172 VHRDLKLENILLDANGNIKIADFGLSNLYHQGKFLQTFCGSPLYASPEIVNGKPYTGPEV 231
           VHRDLK EN+LLDA+ NIKIADFG SN +  G  L TFCGSP YA+PE+  GK Y GPEV
Sbjct: 172 VHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEV 231

Query: 232 DSWSLGVLLYILVHGTMPFDGHDHKILVKQISNGAYREPPKPSDAC-GLIRWLLMVNPTR 290
           D WSLGV+LY LV G++PFDG + K L +++  G YR P   S  C  L++  L++NP++
Sbjct: 232 DVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSK 291

Query: 291 RATLEDVASHWWVNWGY 307
           R TLE +    W+N G+
Sbjct: 292 RGTLEQIMKDRWMNVGH 308


>gi|254028234 MAP/microtubule affinity-regulating kinase 2 isoform d
           [Homo sapiens]
          Length = 788

 Score =  253 bits (646), Expect = 4e-67
 Identities = 130/257 (50%), Positives = 175/257 (68%), Gaps = 3/257 (1%)

Query: 53  YEFLETLGKGTYGKVKKARES-SGRLVAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHPH 111
           Y  L+T+GKG + KVK AR   +G+ VA+K I K ++ +   L  + RE+ IM  LNHP+
Sbjct: 53  YRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQL-NSSSLQKLFREVRIMKVLNHPN 111

Query: 112 IIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCHQNRV 171
           I+ + EV E    + +VMEYAS G+++DY+    ++ E+EAR  FRQIVSAV YCHQ  +
Sbjct: 112 IVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFI 171

Query: 172 VHRDLKLENILLDANGNIKIADFGLSNLYHQGKFLQTFCGSPLYASPEIVNGKPYTGPEV 231
           VHRDLK EN+LLDA+ NIKIADFG SN +  G  L TFCGSP YA+PE+  GK Y GPEV
Sbjct: 172 VHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEV 231

Query: 232 DSWSLGVLLYILVHGTMPFDGHDHKILVKQISNGAYREPPKPSDAC-GLIRWLLMVNPTR 290
           D WSLGV+LY LV G++PFDG + K L +++  G YR P   S  C  L++  L++NP++
Sbjct: 232 DVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSK 291

Query: 291 RATLEDVASHWWVNWGY 307
           R TLE +    W+N G+
Sbjct: 292 RGTLEQIMKDRWMNVGH 308


>gi|254028232 MAP/microtubule affinity-regulating kinase 2 isoform c
           [Homo sapiens]
          Length = 724

 Score =  253 bits (646), Expect = 4e-67
 Identities = 130/257 (50%), Positives = 175/257 (68%), Gaps = 3/257 (1%)

Query: 53  YEFLETLGKGTYGKVKKARES-SGRLVAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHPH 111
           Y  L+T+GKG + KVK AR   +G+ VA+K I K ++ +   L  + RE+ IM  LNHP+
Sbjct: 53  YRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQL-NSSSLQKLFREVRIMKVLNHPN 111

Query: 112 IIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCHQNRV 171
           I+ + EV E    + +VMEYAS G+++DY+    ++ E+EAR  FRQIVSAV YCHQ  +
Sbjct: 112 IVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFI 171

Query: 172 VHRDLKLENILLDANGNIKIADFGLSNLYHQGKFLQTFCGSPLYASPEIVNGKPYTGPEV 231
           VHRDLK EN+LLDA+ NIKIADFG SN +  G  L TFCGSP YA+PE+  GK Y GPEV
Sbjct: 172 VHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEV 231

Query: 232 DSWSLGVLLYILVHGTMPFDGHDHKILVKQISNGAYREPPKPSDAC-GLIRWLLMVNPTR 290
           D WSLGV+LY LV G++PFDG + K L +++  G YR P   S  C  L++  L++NP++
Sbjct: 232 DVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSK 291

Query: 291 RATLEDVASHWWVNWGY 307
           R TLE +    W+N G+
Sbjct: 292 RGTLEQIMKDRWMNVGH 308


>gi|86990441 MAP/microtubule affinity-regulating kinase 2 isoform a
           [Homo sapiens]
          Length = 745

 Score =  253 bits (646), Expect = 4e-67
 Identities = 130/257 (50%), Positives = 175/257 (68%), Gaps = 3/257 (1%)

Query: 53  YEFLETLGKGTYGKVKKARES-SGRLVAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHPH 111
           Y  L+T+GKG + KVK AR   +G+ VA+K I K ++ +   L  + RE+ IM  LNHP+
Sbjct: 20  YRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQL-NSSSLQKLFREVRIMKVLNHPN 78

Query: 112 IIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCHQNRV 171
           I+ + EV E    + +VMEYAS G+++DY+    ++ E+EAR  FRQIVSAV YCHQ  +
Sbjct: 79  IVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFI 138

Query: 172 VHRDLKLENILLDANGNIKIADFGLSNLYHQGKFLQTFCGSPLYASPEIVNGKPYTGPEV 231
           VHRDLK EN+LLDA+ NIKIADFG SN +  G  L TFCGSP YA+PE+  GK Y GPEV
Sbjct: 139 VHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEV 198

Query: 232 DSWSLGVLLYILVHGTMPFDGHDHKILVKQISNGAYREPPKPSDAC-GLIRWLLMVNPTR 290
           D WSLGV+LY LV G++PFDG + K L +++  G YR P   S  C  L++  L++NP++
Sbjct: 199 DVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSK 258

Query: 291 RATLEDVASHWWVNWGY 307
           R TLE +    W+N G+
Sbjct: 259 RGTLEQIMKDRWMNVGH 275


>gi|153791472 MAP/microtubule affinity-regulating kinase 1 [Homo
           sapiens]
          Length = 795

 Score =  249 bits (637), Expect = 4e-66
 Identities = 129/257 (50%), Positives = 173/257 (67%), Gaps = 3/257 (1%)

Query: 53  YEFLETLGKGTYGKVKKARES-SGRLVAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHPH 111
           Y   +T+GKG + KVK AR   +GR VA+K I K ++ +   L  + RE+ IM  LNHP+
Sbjct: 60  YRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQL-NPTSLQKLFREVRIMKILNHPN 118

Query: 112 IIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCHQNRV 171
           I+ + EV E    + +VMEYAS G+++DY+    ++ E+EAR  FRQIVSAV YCHQ  +
Sbjct: 119 IVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYI 178

Query: 172 VHRDLKLENILLDANGNIKIADFGLSNLYHQGKFLQTFCGSPLYASPEIVNGKPYTGPEV 231
           VHRDLK EN+LLD + NIKIADFG SN +  G  L TFCGSP YA+PE+  GK Y GPEV
Sbjct: 179 VHRDLKAENLLLDGDMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEV 238

Query: 232 DSWSLGVLLYILVHGTMPFDGHDHKILVKQISNGAYREPPKPSDAC-GLIRWLLMVNPTR 290
           D WSLGV+LY LV G++PFDG + K L +++  G YR P   S  C  L++ LL++NP +
Sbjct: 239 DVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKLLVLNPIK 298

Query: 291 RATLEDVASHWWVNWGY 307
           R +LE +    W+N G+
Sbjct: 299 RGSLEQIMKDRWMNVGH 315


>gi|94557301 protein kinase, AMP-activated, alpha 1 catalytic
           subunit isoform 1 [Homo sapiens]
          Length = 559

 Score =  244 bits (623), Expect = 2e-64
 Identities = 125/265 (47%), Positives = 178/265 (67%), Gaps = 5/265 (1%)

Query: 41  KRHHHKHNLRHRYEFLETLGKGTYGKVKKAR-ESSGRLVAIKSIRKDKIKDEQDLMHIRR 99
           ++H  +  + H Y   +TLG GT+GKVK  + E +G  VA+K + + KI+    +  IRR
Sbjct: 16  QKHDGRVKIGH-YILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRR 74

Query: 100 EIEIMSSLNHPHIIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQI 159
           EI+ +    HPHII +++V    S I +VMEY S G+L+DYI +  +L E+E+R  F+QI
Sbjct: 75  EIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQI 134

Query: 160 VSAVHYCHQNRVVHRDLKLENILLDANGNIKIADFGLSNLYHQGKFLQTFCGSPLYASPE 219
           +S V YCH++ VVHRDLK EN+LLDA+ N KIADFGLSN+   G+FL+T CGSP YA+PE
Sbjct: 135 LSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPE 194

Query: 220 IVNGKPYTGPEVDSWSLGVLLYILVHGTMPFDGHDHKILVKQISNGAYREPP--KPSDAC 277
           +++G+ Y GPEVD WS GV+LY L+ GT+PFD      L K+I +G +  P    PS   
Sbjct: 195 VISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPS-VI 253

Query: 278 GLIRWLLMVNPTRRATLEDVASHWW 302
            L++ +L V+P +RAT++D+  H W
Sbjct: 254 SLLKHMLQVDPMKRATIKDIREHEW 278


>gi|38569491 serine/threonine-protein kinase QSK [Homo sapiens]
          Length = 1263

 Score =  241 bits (616), Expect = 1e-63
 Identities = 124/258 (48%), Positives = 177/258 (68%), Gaps = 3/258 (1%)

Query: 53  YEFLETLGKGTYGKVKKARESSGRL-VAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHPH 111
           YE   T+GKG +  VK+A     +  VAIK I K ++ DE++L  I RE++IM  L HPH
Sbjct: 8   YEIDRTIGKGNFAVVKRATHLVTKAKVAIKIIDKTQL-DEENLKKIFREVQIMKMLCHPH 66

Query: 112 IIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCHQNRV 171
           II +++V E    I +V EYAS G+++D++    +++E+EAR  F+QIV+AV++CH   +
Sbjct: 67  IIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVTAVYFCHCRNI 126

Query: 172 VHRDLKLENILLDANGNIKIADFGLSNLYHQGKFLQTFCGSPLYASPEIVNGKPYTGPEV 231
           VHRDLK EN+LLDAN NIKIADFG SNL+  G+ L+T+CGSP YA+PE+  GK Y GP+V
Sbjct: 127 VHRDLKAENLLLDANLNIKIADFGFSNLFTPGQLLKTWCGSPPYAAPELFEGKEYDGPKV 186

Query: 232 DSWSLGVLLYILVHGTMPFDGHDHKILVKQISNGAYREPPKPSDAC-GLIRWLLMVNPTR 290
           D WSLGV+LY+LV G +PFDG   + L  ++ +G +R P   S  C  LIR +L+++P +
Sbjct: 187 DIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFRIPFFMSTECEHLIRHMLVLDPNK 246

Query: 291 RATLEDVASHWWVNWGYA 308
           R ++E +  H W+  G A
Sbjct: 247 RLSMEQICKHKWMKLGDA 264


>gi|116256471 SNF1-like kinase [Homo sapiens]
          Length = 783

 Score =  239 bits (609), Expect = 7e-63
 Identities = 121/253 (47%), Positives = 167/253 (66%), Gaps = 3/253 (1%)

Query: 53  YEFLETLGKGTYGKVKKARESSGRL-VAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHPH 111
           Y+   TLGKG +  VK AR    +  VAIK I K ++ D  +L  I RE+++M  LNHPH
Sbjct: 27  YDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRL-DSSNLEKIYREVQLMKLLNHPH 85

Query: 112 IIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCHQNRV 171
           II +++V E    + IV E+A  G+++DY++    LSE EAR  F QI+SAV YCH + +
Sbjct: 86  IIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILSAVEYCHDHHI 145

Query: 172 VHRDLKLENILLDANGNIKIADFGLSNLYHQGKFLQTFCGSPLYASPEIVNGKPYTGPEV 231
           VHRDLK EN+LLD N +IK+ADFG  N Y  G+ L T+CGSP YA+PE+  GK Y GP++
Sbjct: 146 VHRDLKTENLLLDGNMDIKLADFGFGNFYKSGEPLSTWCGSPPYAAPEVFEGKEYEGPQL 205

Query: 232 DSWSLGVLLYILVHGTMPFDGHDHKILVKQISNGAYREPPKPSDAC-GLIRWLLMVNPTR 290
           D WSLGV+LY+LV G++PFDG +   L +++  G +R P   S  C  LIR +L+V+P R
Sbjct: 206 DIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPFFMSQDCESLIRRMLVVDPAR 265

Query: 291 RATLEDVASHWWV 303
           R T+  +  H W+
Sbjct: 266 RITIAQIRQHRWM 278


>gi|46877068 AMP-activated protein kinase alpha 2 catalytic subunit
           [Homo sapiens]
          Length = 552

 Score =  236 bits (603), Expect = 4e-62
 Identities = 120/264 (45%), Positives = 173/264 (65%), Gaps = 3/264 (1%)

Query: 41  KRHHHKHNLRHRYEFLETLGKGTYGKVK-KARESSGRLVAIKSIRKDKIKDEQDLMHIRR 99
           ++H  +  + H Y   +TLG GT+GKVK    + +G  VA+K + + KI+    +  I+R
Sbjct: 5   QKHDGRVKIGH-YVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKR 63

Query: 100 EIEIMSSLNHPHIIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQI 159
           EI+ +    HPHII +++V    +   +VMEY S G+L+DYI +  ++ E EAR  F+QI
Sbjct: 64  EIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQI 123

Query: 160 VSAVHYCHQNRVVHRDLKLENILLDANGNIKIADFGLSNLYHQGKFLQTFCGSPLYASPE 219
           +SAV YCH++ VVHRDLK EN+LLDA+ N KIADFGLSN+   G+FL+T CGSP YA+PE
Sbjct: 124 LSAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPE 183

Query: 220 IVNGKPYTGPEVDSWSLGVLLYILVHGTMPFDGHDHKILVKQISNGAYREPPKPS-DACG 278
           +++G+ Y GPEVD WS GV+LY L+ GT+PFD      L K+I  G +  P   +     
Sbjct: 184 VISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVAT 243

Query: 279 LIRWLLMVNPTRRATLEDVASHWW 302
           L+  +L V+P +RAT++D+  H W
Sbjct: 244 LLMHMLQVDPLKRATIKDIREHEW 267


>gi|94557299 protein kinase, AMP-activated, alpha 1 catalytic
           subunit isoform 2 [Homo sapiens]
          Length = 574

 Score =  236 bits (601), Expect = 6e-62
 Identities = 125/280 (44%), Positives = 179/280 (63%), Gaps = 20/280 (7%)

Query: 41  KRHHHKHNLRHRYEFLETLGKGTYGKVKKAR-ESSGRLVAIKSIRKDKIKDEQDLMHIRR 99
           ++H  +  + H Y   +TLG GT+GKVK  + E +G  VA+K + + KI+    +  IRR
Sbjct: 16  QKHDGRVKIGH-YILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRR 74

Query: 100 EIEIMSSLNHPHIIAIHEVFENSSKIVIVMEYASRGDLYDYISER--------------- 144
           EI+ +    HPHII +++V    S I +VMEY S G+L+DYI +                
Sbjct: 75  EIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRKSDVPGVVKTGST 134

Query: 145 QQLSEREARHFFRQIVSAVHYCHQNRVVHRDLKLENILLDANGNIKIADFGLSNLYHQGK 204
           ++L E+E+R  F+QI+S V YCH++ VVHRDLK EN+LLDA+ N KIADFGLSN+   G+
Sbjct: 135 KELDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGE 194

Query: 205 FLQTFCGSPLYASPEIVNGKPYTGPEVDSWSLGVLLYILVHGTMPFDGHDHKILVKQISN 264
           FL+T CGSP YA+PE+++G+ Y GPEVD WS GV+LY L+ GT+PFD      L K+I +
Sbjct: 195 FLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICD 254

Query: 265 GAYREPP--KPSDACGLIRWLLMVNPTRRATLEDVASHWW 302
           G +  P    PS    L++ +L V+P +RAT++D+  H W
Sbjct: 255 GIFYTPQYLNPS-VISLLKHMLQVDPMKRATIKDIREHEW 293


>gi|38569460 SNF1-like kinase 2 [Homo sapiens]
          Length = 926

 Score =  234 bits (596), Expect = 2e-61
 Identities = 118/253 (46%), Positives = 169/253 (66%), Gaps = 3/253 (1%)

Query: 53  YEFLETLGKGTYGKVKKARESSGRL-VAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHPH 111
           Y+   TLGKG +  VK  R    +  VAIK I K ++ D  +L  I RE++IM  L+HPH
Sbjct: 20  YDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQL-DAVNLEKIYREVQIMKMLDHPH 78

Query: 112 IIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCHQNRV 171
           II +++V E  S + +V EYA  G+++DY++   +L+E EAR  F QI+SAV YCH  ++
Sbjct: 79  IIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRKI 138

Query: 172 VHRDLKLENILLDANGNIKIADFGLSNLYHQGKFLQTFCGSPLYASPEIVNGKPYTGPEV 231
           VHRDLK EN+LLD N NIKIADFG  N +  G+ L T+CGSP YA+PE+  G+ Y GP++
Sbjct: 139 VHRDLKAENLLLDNNMNIKIADFGFGNFFKSGELLATWCGSPPYAAPEVFEGQQYEGPQL 198

Query: 232 DSWSLGVLLYILVHGTMPFDGHDHKILVKQISNGAYREPPKPSDAC-GLIRWLLMVNPTR 290
           D WS+GV+LY+LV G +PFDG    IL +++  G +R P   S+ C  LIR +L+++P++
Sbjct: 199 DIWSMGVVLYVLVCGALPFDGPTLPILRQRVLEGRFRIPYFMSEDCEHLIRRMLVLDPSK 258

Query: 291 RATLEDVASHWWV 303
           R T+  +  H W+
Sbjct: 259 RLTIAQIKEHKWM 271


>gi|24308326 BR serine/threonine kinase 1 [Homo sapiens]
          Length = 778

 Score =  221 bits (562), Expect = 2e-57
 Identities = 110/267 (41%), Positives = 167/267 (62%), Gaps = 8/267 (2%)

Query: 43  HHHKHNLRHR-----YEFLETLGKGTYGKVKKARES-SGRLVAIKSIRKDKIKDEQDLMH 96
           H H H  +H      Y   +TLGKG  G VK      +G+ VAIK + ++K+  E  LM 
Sbjct: 19  HPHPHPPQHAQYVGPYRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNREKLS-ESVLMK 77

Query: 97  IRREIEIMSSLNHPHIIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFF 156
           + REI I+  + HPH++ +H+V+EN   + +V+E+ S G+L+DY+ ++ +L+ +EAR FF
Sbjct: 78  VEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFF 137

Query: 157 RQIVSAVHYCHQNRVVHRDLKLENILLDANGNIKIADFGLSNLYHQGKFLQTFCGSPLYA 216
           RQIVSA+ +CH   + HRDLK EN+LLD   NI+IADFG+++L      L+T CGSP YA
Sbjct: 138 RQIVSALDFCHSYSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYA 197

Query: 217 SPEIVNGKPYTGPEVDSWSLGVLLYILVHGTMPFDGHDHKILVKQISNGAYREPP-KPSD 275
            PE++ G+ Y G   D WS GV+L+ L+ G +PFD  + + L++++  G +  P   P D
Sbjct: 198 CPEVIKGEKYDGRRADMWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPD 257

Query: 276 ACGLIRWLLMVNPTRRATLEDVASHWW 302
              L+R ++ V P +R +LE +  H W
Sbjct: 258 CQSLLRGMIEVEPEKRLSLEQIQKHPW 284


>gi|116089335 BR serine/threonine kinase 2 [Homo sapiens]
          Length = 668

 Score =  218 bits (556), Expect = 1e-56
 Identities = 142/450 (31%), Positives = 229/450 (50%), Gaps = 38/450 (8%)

Query: 53  YEFLETLGKGTYGKVKKARES-SGRLVAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHPH 111
           Y   +TLGKG  G VK      + + VAIK + ++K+  E  LM + REI I+  + HPH
Sbjct: 19  YRLEKTLGKGQTGLVKLGVHCVTCQKVAIKIVNREKLS-ESVLMKVEREIAILKLIEHPH 77

Query: 112 IIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCHQNRV 171
           ++ +H+V+EN   + +V+E+ S G+L+DY+ ++ +L+ +EAR FFRQI+SA+ +CH + +
Sbjct: 78  VLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSI 137

Query: 172 VHRDLKLENILLDANGNIKIADFGLSNLYHQGKFLQTFCGSPLYASPEIVNGKPYTGPEV 231
            HRDLK EN+LLD   NI+IADFG+++L      L+T CGSP YA PE++ G+ Y G + 
Sbjct: 138 CHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKA 197

Query: 232 DSWSLGVLLYILVHGTMPFDGHDHKILVKQISNGAYREPP-KPSDACGLIRWLLMVNPTR 290
           D WS GV+L+ L+ G +PFD  + + L++++  G +  P   P D   L+R ++ V+  R
Sbjct: 198 DVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVDAAR 257

Query: 291 RATLEDVASHWWVNWGYATRVGEQEAPHE---GGHPGSDSARASMADWLR-----RSSRP 342
           R TLE +  H W   G      EQ  P +      P  +     + D +      R    
Sbjct: 258 RLTLEHIQKHIWYIGGKNEPEPEQPIPRKVQIRSLPSLEDIDPDVLDSMHSLGCFRDRNK 317

Query: 343 LL-------ENGAKVCSFF------------KQHAPGGGSTTPGLERQHS--LKKSRKEN 381
           LL       EN  K+  F              +  P      P  +R  S  L +  K  
Sbjct: 318 LLQDLLSEEENQEKMIYFLLLDRKERYPSQEDEDLPPRNEIDPPRKRVDSPMLNRHGKRR 377

Query: 382 DMAQSLH-SDTADDTAHRPGKSNLKLPK-GILKKKVSASAEGVQEDP---PELSPIPASP 436
              +S+      D  +  P +  +++ + G   + +S ++ G+   P   P ++P P+  
Sbjct: 378 PERKSMEVLSVTDGGSPVPARRAIEMAQHGQRSRSISGASSGLSTSPLSSPRVTPHPSPR 437

Query: 437 GQAAPLLPKKGILKKPRQRESGYYSSPEPS 466
           G   P  PK   +  P++  +G  +   PS
Sbjct: 438 GSPLP-TPKGTPVHTPKESPAGTPNPTPPS 466


>gi|7661974 maternal embryonic leucine zipper kinase [Homo sapiens]
          Length = 651

 Score =  197 bits (500), Expect = 3e-50
 Identities = 111/260 (42%), Positives = 156/260 (60%), Gaps = 8/260 (3%)

Query: 53  YEFLETLGKGTYGKVKKARES-SGRLVAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHPH 111
           YE  ET+G G + KVK A    +G +VAIK + K+ +    DL  I+ EIE + +L H H
Sbjct: 11  YELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLGS--DLPRIKTEIEALKNLRHQH 68

Query: 112 IIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCHQNRV 171
           I  ++ V E ++KI +V+EY   G+L+DYI  + +LSE E R  FRQIVSAV Y H    
Sbjct: 69  ICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGY 128

Query: 172 VHRDLKLENILLDANGNIKIADFGLSNLYHQGK--FLQTFCGSPLYASPEIVNGKPYTGP 229
            HRDLK EN+L D    +K+ DFGL       K   LQT CGS  YA+PE++ GK Y G 
Sbjct: 129 AHRDLKPENLLFDEYHKLKLIDFGLCAKPKGNKDYHLQTCCGSLAYAAPELIQGKSYLGS 188

Query: 230 EVDSWSLGVLLYILVHGTMPFDGHDHKILVKQISNGAYREPP--KPSDACGLIRWLLMVN 287
           E D WS+G+LLY+L+ G +PFD  +   L K+I  G Y  P    PS    L++ +L V+
Sbjct: 189 EADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPKWLSPSSIL-LLQQMLQVD 247

Query: 288 PTRRATLEDVASHWWVNWGY 307
           P +R +++++ +H W+   Y
Sbjct: 248 PKKRISMKNLLNHPWIMQDY 267


>gi|23503303 serine/threonine-protein kinase NIM1 [Homo sapiens]
          Length = 436

 Score =  195 bits (496), Expect = 9e-50
 Identities = 108/253 (42%), Positives = 152/253 (60%), Gaps = 3/253 (1%)

Query: 53  YEFLETLGKGTYGKVKKARES-SGRLVAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHPH 111
           Y     +G G + +VK    S +   VAIK + K K+ D++    + REI  M  L+HP+
Sbjct: 74  YRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKL-DQKTQRLLSREISSMEKLHHPN 132

Query: 112 IIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCHQNRV 171
           II ++EV E  SK+ +VMEYA  G+L+  IS   +LSE E++  F QIVSAV + H+N++
Sbjct: 133 IIRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQIVSAVKHMHENQI 192

Query: 172 VHRDLKLENILLDANGNIKIADFGLSNLYHQGKFLQTFCGSPLYASPEIVNGKPYTGPEV 231
           +HRDLK EN+   +N  +K+ DFG S +  +G+ L TFCGSP YA+PE+   + Y G  V
Sbjct: 193 IHRDLKAENVFYTSNTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDEHYIGIYV 252

Query: 232 DSWSLGVLLYILVHGTMPFDGHDHKILVKQISNGAYREPPKPSDAC-GLIRWLLMVNPTR 290
           D W+LGVLLY +V GTMPF       L K I  G Y  PP  S+ C  LIR +L   PT 
Sbjct: 253 DIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYSVPPHVSEPCHRLIRGVLQQIPTE 312

Query: 291 RATLEDVASHWWV 303
           R  ++ + +  W+
Sbjct: 313 RYGIDCIMNDEWM 325


>gi|156105707 SNF related kinase [Homo sapiens]
          Length = 765

 Score =  186 bits (473), Expect = 4e-47
 Identities = 102/255 (40%), Positives = 155/255 (60%), Gaps = 5/255 (1%)

Query: 53  YEFLETLGKGTYGKVKKARES-SGRLVAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHPH 111
           Y+  +TLG+G +  VK AR   +G  VA+K I K K+ D     H+ +E+  M  + HP+
Sbjct: 16  YDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKL-DTLATGHLFQEVRCMKLVQHPN 74

Query: 112 IIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQ-LSEREARHFFRQIVSAVHYCHQNR 170
           I+ ++EV +  +K+ +++E    GD++DYI + ++ L+E  A+ +F QIV A+ YCH+  
Sbjct: 75  IVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISYCHKLH 134

Query: 171 VVHRDLKLENILL-DANGNIKIADFGLSNLYHQGKFLQTFCGSPLYASPEIVNGKPYTGP 229
           VVHRDLK EN++  +  G +K+ DFG SN +  GK L T CGS  Y++PEI+ G  Y  P
Sbjct: 135 VVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKKLTTSCGSLAYSAPEILLGDEYDAP 194

Query: 230 EVDSWSLGVLLYILVHGTMPFDGHDHKILVKQISNGAYREPPKPSDAC-GLIRWLLMVNP 288
            VD WSLGV+L++LV G  PF   +    +  I +  Y  P   S  C  LI  +L  +P
Sbjct: 195 AVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMDCKYTVPSHVSKECKDLITRMLQRDP 254

Query: 289 TRRATLEDVASHWWV 303
            RRA+LE++ +H W+
Sbjct: 255 KRRASLEEIENHPWL 269


>gi|156105705 SNF related kinase [Homo sapiens]
          Length = 765

 Score =  186 bits (473), Expect = 4e-47
 Identities = 102/255 (40%), Positives = 155/255 (60%), Gaps = 5/255 (1%)

Query: 53  YEFLETLGKGTYGKVKKARES-SGRLVAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHPH 111
           Y+  +TLG+G +  VK AR   +G  VA+K I K K+ D     H+ +E+  M  + HP+
Sbjct: 16  YDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKL-DTLATGHLFQEVRCMKLVQHPN 74

Query: 112 IIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQ-LSEREARHFFRQIVSAVHYCHQNR 170
           I+ ++EV +  +K+ +++E    GD++DYI + ++ L+E  A+ +F QIV A+ YCH+  
Sbjct: 75  IVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISYCHKLH 134

Query: 171 VVHRDLKLENILL-DANGNIKIADFGLSNLYHQGKFLQTFCGSPLYASPEIVNGKPYTGP 229
           VVHRDLK EN++  +  G +K+ DFG SN +  GK L T CGS  Y++PEI+ G  Y  P
Sbjct: 135 VVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKKLTTSCGSLAYSAPEILLGDEYDAP 194

Query: 230 EVDSWSLGVLLYILVHGTMPFDGHDHKILVKQISNGAYREPPKPSDAC-GLIRWLLMVNP 288
            VD WSLGV+L++LV G  PF   +    +  I +  Y  P   S  C  LI  +L  +P
Sbjct: 195 AVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMDCKYTVPSHVSKECKDLITRMLQRDP 254

Query: 289 TRRATLEDVASHWWV 303
            RRA+LE++ +H W+
Sbjct: 255 KRRASLEEIENHPWL 269


>gi|4885549 AKT3 kinase isoform 1 [Homo sapiens]
          Length = 479

 Score =  173 bits (438), Expect = 5e-43
 Identities = 92/251 (36%), Positives = 150/251 (59%), Gaps = 4/251 (1%)

Query: 44  HHKHNLRHRYEFLETLGKGTYGKVKKARE-SSGRLVAIKSIRKDKIKDEQDLMHIRREIE 102
           HHK    + +++L+ LGKGT+GKV   RE +SG+  A+K ++K+ I  + ++ H   E  
Sbjct: 139 HHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESR 198

Query: 103 IMSSLNHPHIIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSA 162
           ++ +  HP + ++   F+   ++  VMEY + G+L+ ++S  +  SE   R +  +IVSA
Sbjct: 199 VLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSA 258

Query: 163 VHYCHQNRVVHRDLKLENILLDANGNIKIADFGL-SNLYHQGKFLQTFCGSPLYASPEIV 221
           + Y H  ++V+RDLKLEN++LD +G+IKI DFGL          ++TFCG+P Y +PE++
Sbjct: 259 LDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVL 318

Query: 222 NGKPYTGPEVDSWSLGVLLYILVHGTMPFDGHDHKILVKQISNGAYREP-PKPSDACGLI 280
               Y G  VD W LGV++Y ++ G +PF   DH+ L + I     + P    SDA  L+
Sbjct: 319 EDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLL 377

Query: 281 RWLLMVNPTRR 291
             LL+ +P +R
Sbjct: 378 SGLLIKDPNKR 388


>gi|32307163 AKT3 kinase isoform 2 [Homo sapiens]
          Length = 465

 Score =  173 bits (438), Expect = 5e-43
 Identities = 92/251 (36%), Positives = 150/251 (59%), Gaps = 4/251 (1%)

Query: 44  HHKHNLRHRYEFLETLGKGTYGKVKKARE-SSGRLVAIKSIRKDKIKDEQDLMHIRREIE 102
           HHK    + +++L+ LGKGT+GKV   RE +SG+  A+K ++K+ I  + ++ H   E  
Sbjct: 139 HHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESR 198

Query: 103 IMSSLNHPHIIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSA 162
           ++ +  HP + ++   F+   ++  VMEY + G+L+ ++S  +  SE   R +  +IVSA
Sbjct: 199 VLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSA 258

Query: 163 VHYCHQNRVVHRDLKLENILLDANGNIKIADFGL-SNLYHQGKFLQTFCGSPLYASPEIV 221
           + Y H  ++V+RDLKLEN++LD +G+IKI DFGL          ++TFCG+P Y +PE++
Sbjct: 259 LDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVL 318

Query: 222 NGKPYTGPEVDSWSLGVLLYILVHGTMPFDGHDHKILVKQISNGAYREP-PKPSDACGLI 280
               Y G  VD W LGV++Y ++ G +PF   DH+ L + I     + P    SDA  L+
Sbjct: 319 EDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLL 377

Query: 281 RWLLMVNPTRR 291
             LL+ +P +R
Sbjct: 378 SGLLIKDPNKR 388


>gi|89363047 death-associated protein kinase 1 [Homo sapiens]
          Length = 1430

 Score =  172 bits (436), Expect = 8e-43
 Identities = 101/271 (37%), Positives = 157/271 (57%), Gaps = 14/271 (5%)

Query: 46  KHNLRHRYEFLETLGKGTYGKVKKARE-SSGRLVAIKSIRKDKIKDEQ---DLMHIRREI 101
           + N+   Y+  E LG G +  VKK RE S+G   A K I+K + K  +       I RE+
Sbjct: 6   QENVDDYYDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGVSREDIEREV 65

Query: 102 EIMSSLNHPHIIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVS 161
            I+  + HP++I +HEV+EN + +++++E  + G+L+D+++E++ L+E EA  F +QI++
Sbjct: 66  SILKEIQHPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQILN 125

Query: 162 AVHYCHQNRVVHRDLKLENI-LLDAN---GNIKIADFGLSNLYHQGKFLQTFCGSPLYAS 217
            V+Y H  ++ H DLK ENI LLD N     IKI DFGL++    G   +   G+P + +
Sbjct: 126 GVYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGNEFKNIFGTPEFVA 185

Query: 218 PEIVNGKPYTGPEVDSWSLGVLLYILVHGTMPFDGHDHKILVKQISNGAYR-EPPKPSDA 276
           PEIVN +P  G E D WS+GV+ YIL+ G  PF G   +  +  +S   Y  E    S+ 
Sbjct: 186 PEIVNYEP-LGLEADMWSIGVITYILLSGASPFLGDTKQETLANVSAVNYEFEDEYFSNT 244

Query: 277 CGL----IRWLLMVNPTRRATLEDVASHWWV 303
             L    IR LL+ +P +R T++D   H W+
Sbjct: 245 SALAKDFIRRLLVKDPKKRMTIQDSLQHPWI 275


>gi|14042947 testis-specific serine kinase 1 [Homo sapiens]
          Length = 367

 Score =  172 bits (435), Expect = 1e-42
 Identities = 106/255 (41%), Positives = 147/255 (57%), Gaps = 10/255 (3%)

Query: 59  LGKGTYGKVKKARESSGRL-VAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHPHIIAIHE 117
           LG+G+Y KVK A     +  VAIK I + K   +     + REIEI++ LNH  II  +E
Sbjct: 18  LGEGSYAKVKSAYSERLKFNVAIKIIDRKKAPADFLEKFLPREIEILAMLNHCSIIKTYE 77

Query: 118 VFENS-SKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCHQNRVVHRDL 176
           +FE S  K+ IVME A +GDL + I  R  L E EAR  F Q+  A+ YCH   VVHRDL
Sbjct: 78  IFETSHGKVYIVMELAVQGDLLELIKTRGALHEDEARKKFHQLSLAIKYCHDLDVVHRDL 137

Query: 177 KLENILLDANGNIKIADFGLSNLY---HQGKFL--QTFCGSPLYASPEIVNGKPYTGPEV 231
           K +N+LLD + NIK++DF  S        G+    +TFCGSP YA+PE++ G PY     
Sbjct: 138 KCDNLLLDKDFNIKLSDFSFSKRCLRDDSGRMALSKTFCGSPAYAAPEVLQGIPYQPKVY 197

Query: 232 DSWSLGVLLYILVHGTMPFDGHDHKILV---KQISNGAYREPPKPSDACGLIRWLLMVNP 288
           D WSLGV+LYI+V G+MP+D  + K ++   K+      R      +   LI  +L  + 
Sbjct: 198 DIWSLGVILYIMVCGSMPYDDSNIKKMLRIQKEHRVNFPRSKHLTGECKDLIYHMLQPDV 257

Query: 289 TRRATLEDVASHWWV 303
            RR  ++++ SH W+
Sbjct: 258 NRRLHIDEILSHCWM 272


>gi|4557511 death-associated protein kinase 3 [Homo sapiens]
          Length = 454

 Score =  172 bits (435), Expect = 1e-42
 Identities = 96/271 (35%), Positives = 151/271 (55%), Gaps = 14/271 (5%)

Query: 46  KHNLRHRYEFLETLGKGTYGKVKKARES-SGRLVAIKSIRKDKIKDEQ---DLMHIRREI 101
           + ++   YE  E LG G +  V+K R+  +G+  A K I+K ++   +       I RE+
Sbjct: 6   QEDVEDHYEMGEELGSGQFAIVRKCRQKGTGKEYAAKFIKKRRLSSSRRGVSREEIEREV 65

Query: 102 EIMSSLNHPHIIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVS 161
            I+  + HP+II +H++FEN + +V+++E  S G+L+D+++E++ L+E EA  F +QI+ 
Sbjct: 66  NILREIRHPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILD 125

Query: 162 AVHYCHQNRVVHRDLKLENILL----DANGNIKIADFGLSNLYHQGKFLQTFCGSPLYAS 217
            VHY H  R+ H DLK ENI+L      N  IK+ DFG+++    G   +   G+P + +
Sbjct: 126 GVHYLHSKRIAHFDLKPENIMLLDKNVPNPRIKLIDFGIAHKIEAGNEFKNIFGTPEFVA 185

Query: 218 PEIVNGKPYTGPEVDSWSLGVLLYILVHGTMPFDGHDHKILVKQISNGAYREPPK----- 272
           PEIVN +P  G E D WS+GV+ YIL+ G  PF G   +  +  IS   Y    +     
Sbjct: 186 PEIVNYEP-LGLEADMWSIGVITYILLSGASPFLGETKQETLTNISAVNYDFDEEYFSNT 244

Query: 273 PSDACGLIRWLLMVNPTRRATLEDVASHWWV 303
              A   IR LL+ +P RR T+     H W+
Sbjct: 245 SELAKDFIRRLLVKDPKRRMTIAQSLEHSWI 275


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.133    0.398 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,527,812
Number of Sequences: 37866
Number of extensions: 1529630
Number of successful extensions: 8290
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 735
Number of HSP's successfully gapped in prelim test: 200
Number of HSP's that attempted gapping in prelim test: 5497
Number of HSP's gapped (non-prelim): 1410
length of query: 628
length of database: 18,247,518
effective HSP length: 108
effective length of query: 520
effective length of database: 14,157,990
effective search space: 7362154800
effective search space used: 7362154800
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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