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Search of human proteins with 13540523
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13540523 nucleosomal binding protein 1 [Homo sapiens]
(282 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13540523 nucleosomal binding protein 1 [Homo sapiens] 561 e-160
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 120 2e-27
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 93 2e-19
gi|4759128 solute carrier family 24 (sodium/potassium/calcium ex... 93 2e-19
gi|4557509 cylicin 2 [Homo sapiens] 84 1e-16
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 84 1e-16
gi|221219020 NYD-SP11 protein [Homo sapiens] 81 9e-16
gi|192807336 arsenate resistance protein 2 isoform e [Homo sapiens] 81 9e-16
gi|192807332 arsenate resistance protein 2 isoform c [Homo sapiens] 81 9e-16
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 81 1e-15
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 81 1e-15
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 80 3e-15
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 80 3e-15
gi|21735415 centromere protein B [Homo sapiens] 79 4e-15
gi|192807334 arsenate resistance protein 2 isoform d [Homo sapiens] 79 4e-15
gi|58331218 arsenate resistance protein 2 isoform a [Homo sapiens] 79 4e-15
gi|157738619 smoothelin-like 1 [Homo sapiens] 77 2e-14
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 77 2e-14
gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens] 76 3e-14
gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens] 76 3e-14
gi|55956788 nucleolin [Homo sapiens] 76 3e-14
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 74 1e-13
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 74 1e-13
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 74 2e-13
gi|60498973 myelin transcription factor 1-like [Homo sapiens] 73 3e-13
gi|190014588 PC4 and SFRS1 interacting protein 1 isoform 2 [Homo... 72 4e-13
gi|19923653 PC4 and SFRS1 interacting protein 1 isoform 2 [Homo ... 72 4e-13
gi|221316599 chromogranin B precursor [Homo sapiens] 71 9e-13
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 71 1e-12
gi|24415404 MDN1, midasin homolog [Homo sapiens] 71 1e-12
>gi|13540523 nucleosomal binding protein 1 [Homo sapiens]
Length = 282
Score = 561 bits (1446), Expect = e-160
Identities = 282/282 (100%), Positives = 282/282 (100%)
Query: 1 MPKRKAAGQGDMRQEPKRRSARLSAMLVPVTPEVKPKRTSSSRKMKTKSDMMEENIDTSA 60
MPKRKAAGQGDMRQEPKRRSARLSAMLVPVTPEVKPKRTSSSRKMKTKSDMMEENIDTSA
Sbjct: 1 MPKRKAAGQGDMRQEPKRRSARLSAMLVPVTPEVKPKRTSSSRKMKTKSDMMEENIDTSA 60
Query: 61 QAVAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVA 120
QAVAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVA
Sbjct: 61 QAVAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVA 120
Query: 121 AEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGE 180
AEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGE
Sbjct: 121 AEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGE 180
Query: 181 DGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKEREDGKE 240
DGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKEREDGKE
Sbjct: 181 DGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKEREDGKE 240
Query: 241 DEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDDGKKEEPQSIV 282
DEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDDGKKEEPQSIV
Sbjct: 241 DEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDDGKKEEPQSIV 282
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 120 bits (300), Expect = 2e-27
Identities = 89/252 (35%), Positives = 144/252 (57%), Gaps = 23/252 (9%)
Query: 48 KSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKN-GEAKITEAPASEKEIV-EVKEENI 105
+ + EE + V E K E EE+ E + GE + E E+E + +EE
Sbjct: 804 RGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGE 863
Query: 106 EDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEA-GKEDKDEKGEEDGKEDKNGN 164
E E+ GE+ E E + E E ++E E + EE+GE G+E+ + +GEE+ E K G
Sbjct: 864 EGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGK-GE 922
Query: 165 EKGEDAK---EKEDGK-KGEDGKGNG--EDGKEKGEDEKEEEDRKETGDGK--------E 210
E+GE+ + E+E+G+ +GEDG+G G E+G+ +GE+E+ E + +E G+G+ E
Sbjct: 923 EEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGE 982
Query: 211 NEDGKEKGDKKEGKDVKVKEDEKERE---DGKEDEGG--NEEEAGKEKEDLKEEEEGKEE 265
E+G+ +G+++EG++ +E E E E +G+E+E G E G+E E EEEEG+EE
Sbjct: 983 EEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEE 1042
Query: 266 DEIKEDDGKKEE 277
E +E +G+ EE
Sbjct: 1043 GEEREKEGEGEE 1054
Score = 119 bits (298), Expect = 3e-27
Identities = 85/259 (32%), Positives = 149/259 (57%), Gaps = 20/259 (7%)
Query: 33 EVKPKRTSSSRKMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKITEAPA 92
E + ++ RK + ++ E+ + Q E ++ E E + GE + E
Sbjct: 765 EGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEE---TEGRGEEKEEGGEVEGGEVEE 821
Query: 93 SEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGK-EDKDE 151
+ E E +EE + E GE++E E + E + ++E EE + EE+GE G+ E ++E
Sbjct: 822 GKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEE 881
Query: 152 KGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEE---EDRKETGDG 208
+GE +G+E+ G +GE+ + + +G++ +G+G E+G+ KGE+E EE E +E G+G
Sbjct: 882 EGEGEGEEE--GEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEG 939
Query: 209 KENEDGKEKGDKKEGK-DVKVKEDEKERE-----DGKEDEGGNEEEAGK-EKEDLKEEEE 261
E EDG+ +G+++EG+ + + +E E E E +G+E EG EEE G+ E E+ + EEE
Sbjct: 940 -EGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEE 998
Query: 262 GKEEDEIKED---DGKKEE 277
G+EE E +E+ +G++EE
Sbjct: 999 GEEEGEGEEEGEGEGEEEE 1017
Score = 119 bits (297), Expect = 4e-27
Identities = 88/296 (29%), Positives = 148/296 (50%), Gaps = 29/296 (9%)
Query: 5 KAAGQGDMRQ--EPKRRSARLSAMLVPVTPEVKPKRTSSSRKMKTKSDMMEENIDTSAQA 62
K G+G+M + E ++ A E + K + + +M E + +
Sbjct: 679 KDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEG 738
Query: 63 VAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENI----------------E 106
E EE E + GE + E ++E KEE E
Sbjct: 739 EEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEE 798
Query: 107 DATE-KGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGE----AGKEDKDEKGEEDGKEDK 161
+ TE +G EK+E E EE + E EE++ E +GE G+E++ E EE+G +
Sbjct: 799 EETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEG--EG 856
Query: 162 NGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKK 221
G E+GE+ + +E+G++GE G+G E+G+ +GE+E E E +E G+G+ E+G+ +G+++
Sbjct: 857 KGEEEGEEGEGEEEGEEGE-GEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEE 915
Query: 222 EGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDDGKKEE 277
EG+ +E E+ +G+E+EG E G++ E EEEEG+ E E +E +G+ EE
Sbjct: 916 EGEGKGEEEGEEGEGEGEEEEGEGE---GEDGEGEGEEEEGEWEGEEEEGEGEGEE 968
Score = 117 bits (293), Expect = 1e-26
Identities = 78/237 (32%), Positives = 143/237 (60%), Gaps = 6/237 (2%)
Query: 46 KTKSDMMEENIDTSAQAVAETKQEAVVE-EDYNENAKNGEAKITEAPASEKEIVEVKEEN 104
K K++++ +++ A+ V+E K ++V E ED E +G + + A + E +E+
Sbjct: 620 KEKTEILSDDLTDKAE-VSEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEE-REKG 677
Query: 105 IEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAG-KEDKDEKGEEDGKEDKNG 163
+D E+ E+ +EE +K D E+Q +++ E G +++++++ EE G+E+
Sbjct: 678 EKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGE 737
Query: 164 NEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEG 223
E+ E +E+E+ K+GE GK GE + +GE EKEE +RK+ + E G+E+GD+ EG
Sbjct: 738 GEEEEGDREEEEEKEGE-GKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEG 796
Query: 224 KDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEED-EIKEDDGKKEEPQ 279
++ + + +E+E+G E EGG EE E+E+ +EE EG+EE+ E +E++G+ EE +
Sbjct: 797 EEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEE 853
Score = 115 bits (289), Expect = 3e-26
Identities = 80/262 (30%), Positives = 140/262 (53%), Gaps = 19/262 (7%)
Query: 35 KPKRTSSSRKMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKITEAPASE 94
K +R K + + D E + + E ++ VE E K + E E
Sbjct: 777 KEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGE 836
Query: 95 KEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGE 154
+E E +EE E E+G K E E + EEE ++ + E + EE G+E+ + +GE
Sbjct: 837 EEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGE 896
Query: 155 E---DGKEDKNGNEKGE----DAKEKEDGKKG------EDGKGNGEDGKEKGEDEKEE-E 200
E +G+ ++ G +GE + K +E+G++G E+G+G GEDG+ +GE+E+ E E
Sbjct: 897 EEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWE 956
Query: 201 DRKETGDGKENEDGKEKGDKKEGKDVKVK-----EDEKEREDGKEDEGGNEEEAGKEKED 255
+E G+G+ E+G+ +G++ EG+ + + E+E+ E+G+E+ G EE G+ +E+
Sbjct: 957 GEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEE 1016
Query: 256 LKEEEEGKEEDEIKEDDGKKEE 277
+ E EG+ E E E +G++EE
Sbjct: 1017 EEGEVEGEVEGEEGEGEGEEEE 1038
Score = 112 bits (279), Expect = 5e-25
Identities = 83/220 (37%), Positives = 127/220 (57%), Gaps = 15/220 (6%)
Query: 65 ETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKK-EAVAAEV 123
E +E EE+ E GE + E E+ E +EE E E+ GE + E E
Sbjct: 860 EEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEG 919
Query: 124 KNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGK 183
K EEE + E E + EE+GE ED + +GEE+ E + E+GE E+E +GE+G+
Sbjct: 920 KGEEEGE-EGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGE 978
Query: 184 GNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKERE-DGKEDE 242
G GE+ E+GE E EEE+ +E +G+E +G+E+G EG+ + +E E E E +G+E E
Sbjct: 979 GEGEE--EEGEGEGEEEEGEE--EGEEEGEGEEEG---EGEGEEEEEGEVEGEVEGEEGE 1031
Query: 243 GGNEEEAGKEK-EDLKEEEEGKE----EDEIKEDDGKKEE 277
G EEE G+E+ E+ ++E EG+E +E +E++GK +E
Sbjct: 1032 GEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQE 1071
Score = 110 bits (274), Expect = 2e-24
Identities = 75/214 (35%), Positives = 123/214 (57%), Gaps = 12/214 (5%)
Query: 73 EEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKE 132
EE G ++ EKE+ E +E D E+ +++E + +N+E ++
Sbjct: 672 EEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGG 731
Query: 133 DEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDG-KKGEDGKGNGEDGKE 191
+EE E+ E +E+++EK E +GKE+ G E+ E +EKE+G +K E+ G E G+E
Sbjct: 732 EEEHGEGEEEEGDREEEEEK-EGEGKEEGEG-EEVEGEREKEEGERKKEERAGKEEKGEE 789
Query: 192 KGEDEKEEEDRKETGDGKENEDG--KEKGDKKEGKDVKVKED-----EKEREDGKEDEGG 244
+G D+ E E+ + G G+E E+G E G+ +EGK + +E+ E+E +G+E+EG
Sbjct: 790 EG-DQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGE 848
Query: 245 NEEEAGKEK-EDLKEEEEGKEEDEIKEDDGKKEE 277
EEE G+ K E+ EE EG+EE E E +G++EE
Sbjct: 849 GEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEE 882
Score = 108 bits (271), Expect = 4e-24
Identities = 77/233 (33%), Positives = 130/233 (55%), Gaps = 25/233 (10%)
Query: 67 KQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNE 126
+QE E ++ +N E + E E E +E + E+ EK GE KE E E
Sbjct: 709 EQEQKEREQGHQKERNQEME--EGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGE---E 763
Query: 127 EEDQKEDEEDQNEEKGEAGKEDK-DEKGEEDGKEDKNGNEKGEDAKE--KEDGKKGEDGK 183
E ++E EE + +++ AGKE+K +E+G++ E++ +GE+ +E + +G + E+GK
Sbjct: 764 VEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGK 823
Query: 184 GNGEDGKEKGEDEKEE--------EDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKER 235
G E+ +E+GE E+EE E +E G+GK E+G+E ++EG++ + + +E+E
Sbjct: 824 GEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEG 883
Query: 236 E---------DGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDDGKKEEPQ 279
E +G+E+EG E E E E +EE EGK E+E +E +G+ EE +
Sbjct: 884 EGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEE 936
Score = 105 bits (263), Expect = 3e-23
Identities = 72/219 (32%), Positives = 125/219 (57%), Gaps = 8/219 (3%)
Query: 54 ENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKITEAPAS---EKEIVEVKEENIEDATE 110
E + + E + E EE E + GE + E E+E E + E E+ E
Sbjct: 879 EEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGE 938
Query: 111 KGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDA 170
GE E E + E E ++E+ E + EE+GE E+ + +GEE+ E + E+GE+
Sbjct: 939 GEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEE 998
Query: 171 KEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKE 230
E E+G+ E+G+G GE+ +E+GE E E E + G+G+E E+G+E+G+++E K+ + +E
Sbjct: 999 GE-EEGEGEEEGEGEGEE-EEEGEVEGEVEGEEGEGEGEE-EEGEEEGEERE-KEGEGEE 1054
Query: 231 DEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIK 269
+ + RE+ +E+E G +E G+E+ + ++ EE K+ +IK
Sbjct: 1055 NRRNREE-EEEEEGKYQETGEEENERQDGEEYKKVSKIK 1092
Score = 101 bits (252), Expect = 6e-22
Identities = 70/223 (31%), Positives = 119/223 (53%), Gaps = 7/223 (3%)
Query: 54 ENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGG 113
E + + E ++E E E GE + E E+ E +EE E E+ G
Sbjct: 866 EGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEG 925
Query: 114 EKKEAVAAEVKNE---EEDQKEDEEDQNEEKGEA--GKEDKDEKGEEDGKEDKNGNEKGE 168
E+ E E + E E+ + E EE++ E +GE G+ + +E+GE +G+E + E+ E
Sbjct: 926 EEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEE 985
Query: 169 DAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDV-K 227
E E+ + E+G+ GE G+E+GE E EEE+ E E E+G+ +G+++EG++ +
Sbjct: 986 GEGEGEEEEGEEEGEEEGE-GEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGE 1044
Query: 228 VKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKE 270
+E E E E+ + + EEE GK +E +EE E ++ +E K+
Sbjct: 1045 EREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEYKK 1087
Score = 91.3 bits (225), Expect = 9e-19
Identities = 74/240 (30%), Positives = 123/240 (51%), Gaps = 29/240 (12%)
Query: 58 TSAQAVAETKQEAVVEEDYNENAKNGEAKITEAPASE---------KEIVEVKEENIEDA 108
T+ +A ++ + E E++ E++K + E A+E KE E+ +++ D
Sbjct: 574 TTIEAFSDEEVEIPEEKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDK 633
Query: 109 TEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEK-- 166
E K ++V E ED E D E+G +G E ++ E G++DK E
Sbjct: 634 AEVSEGKAKSVG-----EAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMER 688
Query: 167 -GEDAKE---KEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKE 222
GE KE KE+ KK DG+ + +E+G ++ ++ +E G+ + E +E+GD++E
Sbjct: 689 PGEGEKELAEKEEWKK-RDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREE 747
Query: 223 GKDVKVKEDE-KEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKE-DDGKKEEPQS 280
++ KE E KE +G+E EG E+E G+ K KEE GKEE +E D G+ EE ++
Sbjct: 748 EEE---KEGEGKEEGEGEEVEGEREKEEGERK---KEERAGKEEKGEEEGDQGEGEEEET 801
Score = 84.3 bits (207), Expect = 1e-16
Identities = 69/237 (29%), Positives = 116/237 (48%), Gaps = 26/237 (10%)
Query: 61 QAVAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVA 120
Q + E Q+ + E+ + + +++ E A ++ + + T + +E
Sbjct: 527 QTIGELTQDTALTENDDSDEYEEMSEMKEGKACKQHVSQGIFMTQPATTIEAFSDEEVEI 586
Query: 121 AEVKNEEEDQK-----EDEEDQNEE--KGEAGKEDKDEKGEEDGKEDKNGNE-KGEDAKE 172
E K ED K E E + NEE K G+++K E +D + +E K + E
Sbjct: 587 PEEKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEVSEGKAKSVGE 646
Query: 173 KEDGKKGEDGKGNGEDG-----------KEKGEDEKEEEDRKETGDGKENEDGKEKGDKK 221
EDG +G G G E+G +EKGE +K + + G+G++ KE+ K+
Sbjct: 647 AEDGPEGR-GDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKR 705
Query: 222 EGKDVKVKEDEKEREDGKEDEGGNE-EEAGKEKEDLKEEEEG-KEEDEIKEDDGKKE 276
+G++ +++KERE G + E E EE G+E+ EEEEG +EE+E KE +GK+E
Sbjct: 706 DGEE----QEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEE 758
Score = 65.9 bits (159), Expect = 4e-11
Identities = 57/191 (29%), Positives = 95/191 (49%), Gaps = 25/191 (13%)
Query: 65 ETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVK 124
E + E EE E + GE + E +E EE + E+ GE++ E +
Sbjct: 952 EGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEE-----EEGEGEGEEEEGEEEGEEEGEGE 1006
Query: 125 NEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKG 184
E E + E+EE+ GE E + E+GE +G+E++ G E+GE+ +EKE G
Sbjct: 1007 EEGEGEGEEEEE-----GEVEGEVEGEEGEGEGEEEE-GEEEGEE-REKE---------G 1050
Query: 185 NGEDGKEKGEDEKEEEDR-KETGDGK-ENEDGKE--KGDKKEGKDVKVKEDEKEREDGKE 240
GE+ + E+E+EEE + +ETG+ + E +DG+E K K +G K +++
Sbjct: 1051 EGEENRRNREEEEEEEGKYQETGEEENERQDGEEYKKVSKIKGSVKYGKHKTYQKKSVTN 1110
Query: 241 DEGGNEEEAGK 251
+G +E+ K
Sbjct: 1111 TQGNGKEQRSK 1121
Score = 40.4 bits (93), Expect = 0.002
Identities = 42/143 (29%), Positives = 70/143 (48%), Gaps = 7/143 (4%)
Query: 54 ENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGG 113
E + + E +E EE E GE + E E E VE +E E E+G
Sbjct: 982 EEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGE-VEGEEGEGEGEEEEGE 1040
Query: 114 EKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNE-KG--EDA 170
E+ E E + EE +++ EE++ EE+G+ + ++E +DG+E K ++ KG +
Sbjct: 1041 EEGEEREKEGEGEE-NRRNREEEE-EEEGKYQETGEEENERQDGEEYKKVSKIKGSVKYG 1098
Query: 171 KEKEDGKKG-EDGKGNGEDGKEK 192
K K KK + +GNG++ + K
Sbjct: 1099 KHKTYQKKSVTNTQGNGKEQRSK 1121
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 93.2 bits (230), Expect = 2e-19
Identities = 62/192 (32%), Positives = 105/192 (54%), Gaps = 12/192 (6%)
Query: 88 TEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKE 147
+E E+EI KE E +E+ E++E + K E E +++ E + E+KGE KE
Sbjct: 36 SEIREREREIETRKEGKKERESERKKERRER--EKRKREREKERKRERGKKEKKGERKKE 93
Query: 148 DKDEKGEEDGKEDKNGNEKGEDAK--EKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKET 205
+++ K KE+K G EK + K +KE G+ ++GK + K E+ KE E +KE
Sbjct: 94 ERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEE 153
Query: 206 GDGKENEDGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEE 265
+E E +++ K+E K V KE+E++ ++ KE ++ + +++ K+E E KE
Sbjct: 154 ---REKERERKERKKRERKQVGEKEEERKEKERKE-----RKKRERNRKERKKERERKER 205
Query: 266 DEIKEDDGKKEE 277
E K++ KKEE
Sbjct: 206 RERKKERKKKEE 217
Score = 80.5 bits (197), Expect = 2e-15
Identities = 62/245 (25%), Positives = 119/245 (48%), Gaps = 7/245 (2%)
Query: 37 KRTSSSRKMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKITEAPASEKE 96
K SS +K +++ + ++ + ++ + E E E K +KE
Sbjct: 3 KAISSRAAVKLNTELQMVSCSHISKPCTQPGWQSEIREREREIETRKEGKKERESERKKE 62
Query: 97 IVEVKEENIEDATEKGGE--KKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGE 154
E ++ E E+ E KKE K E E +K E +N+E E K K EK +
Sbjct: 63 RREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEK-K 121
Query: 155 EDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDG 214
E G+ K G E+ + K + +K + K E KE+ E+++ +RK+ G+ +E
Sbjct: 122 ERGRTSKEGKERERKEERKREERKERERK-KEEREKERERKERKKRERKQVGEKEEERKE 180
Query: 215 KEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDDGK 274
KE+ ++K+ ++ KE +KERE +++ ++E K++E KE ++ ++ + +++ GK
Sbjct: 181 KERKERKK-RERNRKERKKERE--RKERRERKKERKKKEERKKERQKDRQTNWREKERGK 237
Query: 275 KEEPQ 279
+E +
Sbjct: 238 RERKE 242
Score = 73.6 bits (179), Expect = 2e-13
Identities = 57/207 (27%), Positives = 108/207 (52%), Gaps = 17/207 (8%)
Query: 65 ETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVK 124
ET++E E E+ + E + E E+E +E ++ +KG KKE + +
Sbjct: 46 ETRKEGKKER---ESERKKERREREKRKREREKERKRERGKKE--KKGERKKEERERKKR 100
Query: 125 NEEEDQKEDEEDQN------EEKGEAGKEDKD-EKGEEDGKEDKNGNEKGEDAKEKE--- 174
E++ KE EE + +E+G KE K+ E+ EE +E++ E+ ++ +EKE
Sbjct: 101 RREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERER 160
Query: 175 DGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKE 234
+K + K GE +E+ E E++E ++E + KE + +E+ +++E K + K++E++
Sbjct: 161 KERKKRERKQVGEKEEERKEKERKERKKRER-NRKERKKERERKERRERKKERKKKEERK 219
Query: 235 REDGKEDEGGNEEEAGKEKEDLKEEEE 261
+E K D N E + K + KE ++
Sbjct: 220 KERQK-DRQTNWREKERGKRERKERKK 245
Score = 71.6 bits (174), Expect = 7e-13
Identities = 48/218 (22%), Positives = 104/218 (47%), Gaps = 15/218 (6%)
Query: 37 KRTSSSRKMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKITEAPASEKE 96
+R +RK K E + + + ++E + + + K GE K E ++
Sbjct: 42 EREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRR 101
Query: 97 IVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEED 156
+ +E E K EKKE + +E ++KE+ + + ++ E KE+++++ E
Sbjct: 102 REKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERK 161
Query: 157 GKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKE 216
++ + + GE +E+++ KE+ E +K E +RKE +E ++ +E
Sbjct: 162 ERKKRERKQVGEKEEERKE--------------KERKERKKRERNRKERKKERERKERRE 207
Query: 217 KGDKKEGKDVKVKEDEKERE-DGKEDEGGNEEEAGKEK 253
+ +++ K+ + KE +K+R+ + +E E G E ++K
Sbjct: 208 RKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
>gi|4759128 solute carrier family 24 (sodium/potassium/calcium
exchanger), member 1 [Homo sapiens]
Length = 1099
Score = 93.2 bits (230), Expect = 2e-19
Identities = 67/227 (29%), Positives = 116/227 (51%), Gaps = 18/227 (7%)
Query: 43 RKMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVK- 101
R+++ + EE+++ A+A + K E+ EE+ E AK +T AP + + + +
Sbjct: 683 REVRLAKEKEEESLNQGARAQPQAKAESKPEEE--EPAKLPAVTVTPAPVPDIKGDQKEN 740
Query: 102 ---EENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGK 158
+E++ +A E GE E ++K E Q E +GE + K E+ E++ +
Sbjct: 741 PGGQEDVAEA-ESTGEMPGEEGETAGEGETEEKSGGETQPEGEGETETQGKGEECEDENE 799
Query: 159 EDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKG 218
+ G+ +GED E EDG+ G +G E E +E + G+ K +E G E G
Sbjct: 800 AEGKGDNEGEDEGEIH----AEDGEMKGNEG----ETESQELSAENHGEAKNDEKGVEDG 851
Query: 219 DKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEE 265
+G D E+E+E E+ +E+E EE+ +E+E+ +EEE+G EE
Sbjct: 852 GGSDGGD---SEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEEKGNEE 895
>gi|4557509 cylicin 2 [Homo sapiens]
Length = 348
Score = 84.0 bits (206), Expect = 1e-16
Identities = 87/299 (29%), Positives = 137/299 (45%), Gaps = 52/299 (17%)
Query: 9 QGDMRQ------EPKRRSARLSAMLVPVTPEVKPKRT----SSSRKMKTKSDMMEENIDT 58
+GD RQ R S R S L +KP RT S + ++ K + DT
Sbjct: 68 RGDRRQPLWMYRSLMRISERPSVYLAARRQPLKPTRTVEVDSKAAEIGKKGEDKTTQKDT 127
Query: 59 SAQAVAETKQEAVVEEDYNENAKNGEAKIT---EAPASEKEIVEVKEENIEDATEKGGEK 115
+ + +E KQ + + K E K+ ++ +K+ + K+ E EKGG K
Sbjct: 128 T-DSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSATESEDEKGGAK 186
Query: 116 KEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKG--EEDGKEDKNGNEKGEDAK-- 171
K D K+D++D N+ K A E + EKG E+D K+ K ++KG+D+
Sbjct: 187 K------------DNKKDKKDSNKGKDSA-TESEGEKGGTEKDSKKGKKDSKKGKDSAIE 233
Query: 172 ---EKEDGKKGEDGK---GNGEDGKEKGEDEKE----EEDRKETG--DGKENEDGKEKGD 219
K D KK EDGK G++ K+ +D KE ++D+K+ D +D K++
Sbjct: 234 LQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESK 293
Query: 220 K---KEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDDGKK 275
K K+ K V K+ EKE D K+D N K+D K++ + + + K+D KK
Sbjct: 294 KDATKDAKKVAKKDTEKESADSKKDAKKN------AKKDAKKDAKKNAKKDEKKDAKKK 346
Score = 83.6 bits (205), Expect = 2e-16
Identities = 66/202 (32%), Positives = 107/202 (52%), Gaps = 24/202 (11%)
Query: 91 PASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKD 150
P VEV + E K GE K + + E + K+ ++D +KG+ ++ K+
Sbjct: 98 PLKPTRTVEVDSKAAEIG--KKGEDK-TTQKDTTDSESELKQGKKDS--KKGKDIEKGKE 152
Query: 151 EK--GEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKE--KGEDEKEEEDRKETG 206
EK ++D K+ K EKG+D+ + + +KG K N +D K+ KG+D E + ++ G
Sbjct: 153 EKLDAKKDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGG 212
Query: 207 DGKENEDGKEKGDKKEGKD-----VKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEE 261
K+++ GK+ D K+GKD VK DEK+ EDGK+D +E+ K+D KE ++
Sbjct: 213 TEKDSKKGKK--DSKKGKDSAIELQAVKADEKKDEDGKKD-ANKGDESKDAKKDAKEIKK 269
Query: 262 GKEE-------DEIKEDDGKKE 276
GK++ D +DD KKE
Sbjct: 270 GKKDKKKPSSTDSDSKDDVKKE 291
Score = 83.6 bits (205), Expect = 2e-16
Identities = 66/221 (29%), Positives = 113/221 (51%), Gaps = 24/221 (10%)
Query: 72 VEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQK 131
V+ E K GE K T+ ++ E E+K+ + K EK + + K + + K
Sbjct: 107 VDSKAAEIGKKGEDKTTQKDTTDSES-ELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGK 165
Query: 132 EDEEDQNEEKG-EAGKEDKDEKG--EEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGED 188
+D E KG ++ E +DEKG ++D K+DK + KG+D+ + +G+KG G +D
Sbjct: 166 KDAE-----KGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKG----GTEKD 216
Query: 189 GKEKGEDEKEEED-----RKETGDGKENEDGKEKGDK-KEGKDVKVKEDEKEREDGKEDE 242
K+ +D K+ +D + D K++EDGK+ +K E KD K+D KE + GK+D+
Sbjct: 217 SKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKD--AKKDAKEIKKGKKDK 274
Query: 243 GGNEEEAGKEKEDLKEE---EEGKEEDEIKEDDGKKEEPQS 280
K+D+K+E + K+ ++ + D +KE S
Sbjct: 275 KKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKESADS 315
Score = 72.0 bits (175), Expect = 5e-13
Identities = 68/263 (25%), Positives = 118/263 (44%), Gaps = 28/263 (10%)
Query: 17 KRRSARLSAMLVPVTP----EVKPKRTSSSRKMKTKSDMMEENIDTS-----------AQ 61
+R S L+A P+ P EV K +K + K+ + S +
Sbjct: 86 ERPSVYLAARRQPLKPTRTVEVDSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGK 145
Query: 62 AVAETKQEAV-VEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVA 120
+ + K+E + ++D + K+ E A SE E K++N +D + K A
Sbjct: 146 DIEKGKEEKLDAKKDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATE 205
Query: 121 AEVK--NEEEDQKEDEEDQNEEKG---EAGKEDKDEKGEEDGKEDKNGNEKGEDAKE--K 173
+E + E+D K+ ++D + K E DEK +EDGK+D N ++ +DAK+ K
Sbjct: 206 SEGEKGGTEKDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAK 265
Query: 174 EDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGK---ENEDGKEKGDKKEGKDVKVKE 230
E K +D K + +D K+E + T D K + + KE D K+ K+
Sbjct: 266 EIKKGKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKK 325
Query: 231 DEKE--REDGKEDEGGNEEEAGK 251
D K+ +++ K+DE + ++ GK
Sbjct: 326 DAKKDAKKNAKKDEKKDAKKKGK 348
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 84.0 bits (206), Expect = 1e-16
Identities = 83/291 (28%), Positives = 130/291 (44%), Gaps = 30/291 (10%)
Query: 2 PKRKAAGQGDMRQEPKRRSARLSAMLV-PVTPEVK-PKRTSSSRKMKTKSDMMEENIDTS 59
P ++ A + + P + A+ PV E K P++ S K KT D+ T
Sbjct: 711 PVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTL-DVKSPEAKTP 769
Query: 60 AQAVAET-------KQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKG 112
A+ A + K ++ V+E+ K +A A EKEI K+E ++ ++
Sbjct: 770 AKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIP--KKEEVKSPVKEE 827
Query: 113 GEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKE 172
+ +E E + E++K + EEK ++ KE+ +K K + EK E A E
Sbjct: 828 EKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVE----EKKEPAVE 883
Query: 173 KEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGD--KKEGKDVKVKE 230
K K E K ED K+ EKE + E KE+ KEK + KKE D K KE
Sbjct: 884 KPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEV---KEDAKPKEKTEVAKKEPDDAKAKE 940
Query: 231 DEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDDGKKEEPQSI 281
K E ++EA EK+D KEE+ K E++ K + KE+ +++
Sbjct: 941 PSKPAE---------KKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTL 982
Score = 78.6 bits (192), Expect = 6e-15
Identities = 74/290 (25%), Positives = 133/290 (45%), Gaps = 16/290 (5%)
Query: 2 PKRKAAGQGDMRQEPKRRSARLSAMLV-PVTPEVK-PKRTSSSRKMKTKS-DMMEENIDT 58
P+++ A + + P + A+ PV E K P++ S K + KS + + +
Sbjct: 655 PEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKE 714
Query: 59 SAQAVAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEA 118
A++ + K E E AK+ + ++P K + K +++ K K+EA
Sbjct: 715 EAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEA 774
Query: 119 VAAEVKNEE-------EDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAK 171
+ K E E+ K E+ ++ K +A +K+ +E+ K EK ++ K
Sbjct: 775 RSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVK 834
Query: 172 EKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKED 231
KE KK E+ K E+ +D K+EE K+ + E+ KE +K K+ KV+
Sbjct: 835 VKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKP-KESKVEAK 893
Query: 232 EKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEI---KEDDGKKEEP 278
++E ED K+ E+ K ++KE+ + KE+ E+ + DD K +EP
Sbjct: 894 KEEAEDKKKVP--TPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEP 941
Score = 73.9 bits (180), Expect = 1e-13
Identities = 77/291 (26%), Positives = 124/291 (42%), Gaps = 27/291 (9%)
Query: 3 KRKAAGQGDMRQEPKRRSARLSAMLVPVTPEVKPKRTSSSRKM------KTKSDMMEENI 56
K K+ + + + K +S + L +PE K +R K KS + EE +
Sbjct: 735 KAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEE-V 793
Query: 57 DTSAQAVAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKE------ENIEDATE 110
+ +A + K++A E E K E K + + V+VKE E AT
Sbjct: 794 KSPEKAKSPLKEDAKAPE--KEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATP 851
Query: 111 KGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAG----KEDKDEKGEEDGKEDKNGNEK 166
K EKK++ K EE +KE + + EEK E KE K E +E+ ++ K
Sbjct: 852 KTEEKKDS-----KKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTP 906
Query: 167 GEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDV 226
++A K + K+ K E K++ +D K +E K ++ E EK D KE K
Sbjct: 907 EKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSK---PAEKKEAAPEKKDTKEEKAK 963
Query: 227 KVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDDGKKEE 277
K +E K KED+ +E K K + E+ ++ + K + E+
Sbjct: 964 KPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATED 1014
Score = 71.6 bits (174), Expect = 7e-13
Identities = 71/251 (28%), Positives = 109/251 (43%), Gaps = 27/251 (10%)
Query: 32 PEVKPKRTSSSRKMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKITEAP 91
PE PK S S +K KS EE I + V ++++E V+ E+ E E ++TE
Sbjct: 423 PEGLPKIPSVSTHIKVKS---EEKI----KVVEKSEKETVIVEEQTE-----ETQVTEEV 470
Query: 92 ASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDE 151
E+E E KEE E E+GGE++EA E ++E + EE KE K
Sbjct: 471 TEEEE-KEAKEE--EGKEEEGGEEEEA--------EGGEEETKSPPAEEAASPEKEAKSP 519
Query: 152 KGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEK--EEEDRKETGDGK 209
EE + + + E+AK + K E K ++ + + K E+E+ K + K
Sbjct: 520 VKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVK 579
Query: 210 ENEDGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIK 269
E K ++ + K EK + KE+ E KE+ K E K ++ K
Sbjct: 580 SPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAK 639
Query: 270 EDDGKKEEPQS 280
KEE +S
Sbjct: 640 SP--TKEEAKS 648
Score = 64.7 bits (156), Expect = 9e-11
Identities = 70/256 (27%), Positives = 106/256 (41%), Gaps = 35/256 (13%)
Query: 2 PKRKAAGQGDMRQEPKRRSARLSAMLVPVTPEVKPKRTSSSRKMKTKSDMMEENIDTSAQ 61
P++ + + + P++ + + PV E KP+ K+K EE A
Sbjct: 796 PEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEV----KVKEPPKKAEEE-KAPAT 850
Query: 62 AVAETKQEAVVEEDYNENAKNGEAKITEAPASEK---EIVEVKEENIEDATEKGGEKKEA 118
E K+++ EE + A + + + PA EK VE K+E ED + +KEA
Sbjct: 851 PKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEA 910
Query: 119 VA-AEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGK 177
A EVK E+ + +EK E K++ D + KE EK E A EK+D K
Sbjct: 911 PAKVEVK---------EDAKPKEKTEVAKKEPD---DAKAKEPSKPAEKKEAAPEKKDTK 958
Query: 178 KGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKERED 237
+ E K+ E K E KE E K K +K E K +++D
Sbjct: 959 E--------EKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAE------KSSSTDQKD 1004
Query: 238 GKEDEGGNEEEAGKEK 253
K E E++A K K
Sbjct: 1005 SKPPEKATEDKAAKGK 1020
Score = 63.5 bits (153), Expect = 2e-10
Identities = 79/302 (26%), Positives = 126/302 (41%), Gaps = 27/302 (8%)
Query: 3 KRKAAGQGDMRQEPKRRSARLSAMLVPVTPEVK-PKRTSSSRKMKTKSDMMEENIDTSAQ 61
K K+ + + + P+ +S P EVK P++ S K + KS ++ + +
Sbjct: 549 KAKSPAKEEAKSPPEAKSPEKEEAKSPA--EVKSPEKAKSPAKEEAKSPAEAKSPEKAKS 606
Query: 62 AVAE-TKQEAVVEEDYNENAKN-GEAKITE---APASEKEIVEVKEENIEDATEKGGEK- 115
V E K A + E AK+ E K E +P E+ K ++ E K EK
Sbjct: 607 PVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKA 666
Query: 116 KEAVAAEVKNEEEDQ---KEDEEDQNEEKGEAGKEDKD-EKGEEDGKEDKNGNEKG---- 167
K V AE K+ E+ + K + + + K +E K EK + KE+ EK
Sbjct: 667 KSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPV 726
Query: 168 -EDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDK-----K 221
E+AK E K + + + E K + + E+ + DK K
Sbjct: 727 KEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAK 786
Query: 222 EGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLK---EEEEGKEEDEIKEDDGKKEEP 278
+VK EK + KED E+E K KE++K +EEE +E ++KE K EE
Sbjct: 787 SPVKEEVKSPEKAKSPLKEDAKAPEKEIPK-KEEVKSPVKEEEKPQEVKVKEPPKKAEEE 845
Query: 279 QS 280
++
Sbjct: 846 KA 847
Score = 62.4 bits (150), Expect = 4e-10
Identities = 65/257 (25%), Positives = 97/257 (37%), Gaps = 12/257 (4%)
Query: 29 PVTPEVK-PKRTSSSRKMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKI 87
PV E K P S K + KS + + +A + K+EA + K
Sbjct: 519 PVKEEAKSPAEAKSPEKEEAKSPA---EVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSP 575
Query: 88 TEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKE 147
E + EK KEE A K EK ++ VK E + E + EE +
Sbjct: 576 AEVKSPEKAKSPAKEEAKSPAEAKSPEKAKS---PVKEEAKSPAEAKSPVKEEAKSPAEV 632
Query: 148 DKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGD 207
EK + KE+ EK + + EKE+ K E K + + E K +
Sbjct: 633 KSPEKAKSPTKEEAKSPEKAK-SPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSP 691
Query: 208 GKENEDGKEKGDKKEGKDVKVKED----EKEREDGKEDEGGNEEEAGKEKEDLKEEEEGK 263
K KE+ E VKE+ EK + KE+ E+ KE+ K E+ K
Sbjct: 692 EKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAK 751
Query: 264 EEDEIKEDDGKKEEPQS 280
++ K D K E ++
Sbjct: 752 SPEKAKTLDVKSPEAKT 768
Score = 60.1 bits (144), Expect = 2e-09
Identities = 81/324 (25%), Positives = 123/324 (37%), Gaps = 53/324 (16%)
Query: 2 PKRKAAGQGDMRQEPKRRSARLSAMLVPVTPEVKPKRTSSSRKMKTKSDMMEENIDTSAQ 61
P ++ A + P++ A+ A + P + + + KS EE A+
Sbjct: 519 PVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEE-----AK 573
Query: 62 AVAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVA- 120
+ AE K + E AK+ EA + EK VKEE A K K+EA +
Sbjct: 574 SPAEVKSPEKAKSPAKEEAKSP----AEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSP 629
Query: 121 AEVKNEE-------EDQKEDEEDQNEEKGEAGKEDK-----------DEKGEEDGKEDKN 162
AEVK+ E E+ K E+ ++ EK EA +K EK + K +
Sbjct: 630 AEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAK 689
Query: 163 GNEKG-----EDAKEKEDGKK------GEDGKGNGEDGKEKGEDEKEEEDRKETGDGKEN 211
EK E+AK E K K +E EK + KE E
Sbjct: 690 SPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEK 749
Query: 212 EDGKEKGD-------------KKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLK- 257
EK K+E + K EK + KE+ E+ KED K
Sbjct: 750 AKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKA 809
Query: 258 EEEEGKEEDEIKEDDGKKEEPQSI 281
E+E +++E+K ++E+PQ +
Sbjct: 810 PEKEIPKKEEVKSPVKEEEKPQEV 833
Score = 56.6 bits (135), Expect = 2e-08
Identities = 77/301 (25%), Positives = 124/301 (41%), Gaps = 27/301 (8%)
Query: 3 KRKAAGQGDMRQEPKRRSARLSAMLVPVTPEVKPKRTSSSRKMKTKSDMMEEN-IDTSAQ 61
K +A +++ K +S P + P++ S K + KS ++ + A+
Sbjct: 569 KEEAKSPAEVKSPEKAKSPAKEEAKSPAEAK-SPEKAKSPVKEEAKSPAEAKSPVKEEAK 627
Query: 62 AVAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEK-KEAVA 120
+ AE K + E AK+ E ++P E+ K ++ A K EK K V
Sbjct: 628 SPAEVKSPEKAKSPTKEEAKSPEK--AKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVK 685
Query: 121 AEVKNEEEDQ---KEDEEDQNEEKGEAGKEDKD-EKGEEDGKEDKNGNEKG-----EDAK 171
AE K+ E+ + KE+ + + K +E K EK + KE+ EK E+AK
Sbjct: 686 AEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAK 745
Query: 172 EKEDGKKGEDGKGNGEDGKEKGEDEKEE-EDRKETGDGKENEDGKEKGDKKEGKDVKVKE 230
E K E K E KEE + K KE+ E +KE
Sbjct: 746 SPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKE 805
Query: 231 DEK--EREDGKEDEGGN--EEEAGKEKEDLKEEEEGKEED--------EIKEDDGKKEEP 278
D K E+E K++E + +EE ++ +KE + EE+ E K+D K+E P
Sbjct: 806 DAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAP 865
Query: 279 Q 279
+
Sbjct: 866 K 866
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 81.3 bits (199), Expect = 9e-16
Identities = 61/229 (26%), Positives = 118/229 (51%), Gaps = 27/229 (11%)
Query: 67 KQEAVVEEDYNENAKNGEAKIT---EAPASEKEIVEVKEENIEDATE--KGGEKKEAVAA 121
K+E + EE+ K+ E + E E+E++ + E +G + KE ++
Sbjct: 2156 KEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSS 2215
Query: 122 EVKNEEEDQKEDEE-----DQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDG 176
+V E ++ EE D+ E++ E+++E+ EE+ +E++ E+ E+ KE+E+G
Sbjct: 2216 QVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEG 2275
Query: 177 KKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKER- 235
E+ + EKEEE++K+ K+ E+ +EK + E K+ + E+E E
Sbjct: 2276 --------------EEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESL 2321
Query: 236 --EDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDDGKKEEPQSIV 282
E+ +E+ EEE +EKE LK+E++ K +++ ++ +E SI+
Sbjct: 2322 SDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQRRKSLRGRERVLSIL 2370
Score = 75.1 bits (183), Expect = 6e-14
Identities = 72/300 (24%), Positives = 139/300 (46%), Gaps = 45/300 (15%)
Query: 17 KRRSARLSAMLVPVTPEVKPKRTSSSRKMKTKSDMMEENIDTSAQAVAETKQE-AVVEED 75
+R+ A+ S L+ + + ++ +K + + + + + TK + A+ ++
Sbjct: 2049 QRKLAKASRKLIKKRESLSKEPAKLNKILKALQKLTRDERKLTQEEIKMTKMKRALFVKE 2108
Query: 76 YNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVK---NEEEDQKE 132
+ + + I E SEK K+E +K K+ +A +++ N+EE E
Sbjct: 2109 RRLSIEQSKLDIKEWDFSEKRSELTKDE------KKLARKQRKLANKMRRMINKEEKMTE 2162
Query: 133 DEEDQNEEKGEAGKEDKDEKGEED-------------GKEDKNGNEKGE------DAKEK 173
+E + E +D++E G E+ KE K G++ E D E
Sbjct: 2163 EESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVES 2222
Query: 174 EDG------------KKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKK 221
E+ +K E E+ +E+ E+ +EEE R+E + KE E+G+EK +K
Sbjct: 2223 EEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEK 2282
Query: 222 EGKDVKVKEDEKEREDGKEDEGGNEEE----AGKEKEDLKEEEEGKEEDEIKEDDGKKEE 277
E ++ K K+ EK++E+ +E E EE+ + +E E L +EEE +E ++E+ +++E
Sbjct: 2283 EEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKE 2342
Score = 67.0 bits (162), Expect = 2e-11
Identities = 55/222 (24%), Positives = 113/222 (50%), Gaps = 20/222 (9%)
Query: 37 KRTSSSRKMKTKSDMMEENIDTSA----QAVAETKQEAVVEEDY-----------NENAK 81
K + R+M K + M E A + + + ++E +EE+ + AK
Sbjct: 2145 KLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAK 2204
Query: 82 NGEAKITEAPASEKEIVEVKE---ENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQN 138
G+ K E +S+ + VE +E E +E ++ EK+E++++E + E E+++E EE++
Sbjct: 2205 RGD-KPKEKFSSQVDEVESEEHFSEEMESLLDEL-EKQESLSSEEEEEREEEEEREEEEV 2262
Query: 139 EEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKE 198
E+ E KE+++ + ++ KE++ +K ++ K++E +K E + E E+ +
Sbjct: 2263 REEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLS 2322
Query: 199 EEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKEREDGKE 240
+E+ +E E E +EK K+ K K++E ++ G+E
Sbjct: 2323 DEEEEEESCSLEEEVDREKEILKKEKQFKLQEQRRKSLRGRE 2364
Score = 49.3 bits (116), Expect = 4e-06
Identities = 45/164 (27%), Positives = 83/164 (50%), Gaps = 12/164 (7%)
Query: 35 KPKRTSSSRKMKTKSDMMEENIDTSAQAVAET--KQEAVV---EEDYNENAKNGEAKITE 89
KPK SS+ + +S EE+ +++ + KQE++ EE+ E + E ++ E
Sbjct: 2208 KPKEKFSSQVDEVES---EEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVRE 2264
Query: 90 APASEKEIVEVKEENIE-DATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKED 148
KE E +E+ +E + EK +KKE EV+ +EE +E EE +EE+ E+
Sbjct: 2265 EEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLS-- 2322
Query: 149 KDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEK 192
DE+ EE+ + ++ ++ +KE K ++ + G+E+
Sbjct: 2323 -DEEEEEESCSLEEEVDREKEILKKEKQFKLQEQRRKSLRGRER 2365
Score = 47.4 bits (111), Expect = 1e-05
Identities = 44/168 (26%), Positives = 80/168 (47%), Gaps = 14/168 (8%)
Query: 2 PKRKAAGQGDMRQEPKRRSARLSAMLVPVTPEVKPKRTSSSRKMKTKSDMMEENIDTSAQ 61
PK K + Q D + + S + ++L E++ + + SS + + + EE + +
Sbjct: 2209 PKEKFSSQVDEVESEEHFSEEMESLL----DELEKQESLSSEEEEER----EEEEEREEE 2260
Query: 62 AVAETKQEAVVEEDYNEN--AKNGEAKITEAPASEKEIVEVKEENIEDATE-KGGEKKEA 118
V E ++E EE+ E K E K + +KE V+ KEE E+ E E+ E+
Sbjct: 2261 EVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETES 2320
Query: 119 VAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEK 166
++ E + EE E+E D+ + E K++K K +E ++ G E+
Sbjct: 2321 LSDEEEEEESCSLEEEVDREK---EILKKEKQFKLQEQRRKSLRGRER 2365
Score = 45.4 bits (106), Expect = 5e-05
Identities = 51/236 (21%), Positives = 103/236 (43%), Gaps = 20/236 (8%)
Query: 40 SSSRKMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKITEAPA------- 92
SS K + D E ++ E K++ V EE + ++ A+I A
Sbjct: 1530 SSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRA 1589
Query: 93 -SEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDE 151
E+++ + +E+ ++ + E+++ A VK ++D+ E Q E K +E +
Sbjct: 1590 QEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDR---EMAQAEGKFAQKEETLAQ 1646
Query: 152 KGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKEN 211
+GE+ +E + +K + +K + E+ K + GK + +E ++N
Sbjct: 1647 RGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQN 1706
Query: 212 EDGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDE 267
D +EK ++ ++ +E E E+ EEE +E+ L EE++ E+E
Sbjct: 1707 LDWQEK---------ELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEE 1753
Score = 40.4 bits (93), Expect = 0.002
Identities = 62/275 (22%), Positives = 116/275 (42%), Gaps = 31/275 (11%)
Query: 3 KRKAAGQGDMRQEPKRRSARLSAMLVPVTPEVKPKRTSSSRKMKTKSDMMEENIDTSAQA 62
+RK A + + + +R+ A+ L + K T R+M + +T AQ
Sbjct: 1592 ERKLAQEEEKLAQEERQLAQEERKLA----QAYVKITQDDREMAQAEGKFAQKEETLAQR 1647
Query: 63 VAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAE 122
+ QEA E K+ A + E V +EE + K E K +A +
Sbjct: 1648 GEKLSQEA-------EKLAQKRKKL----AKKWEKVAREEEKLAKKGGKLAEVKNILAQK 1696
Query: 123 V-----KNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGK 177
V + + D +E E Q E+ E E+ K EE +E+ E+ + E+E+
Sbjct: 1697 VEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEAL 1756
Query: 178 KGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKEN--EDGKEKGDKKE---GKDVKVKEDE 232
+ K + E+ K E+E +++++ KE E+ + G K+E K +K+ +
Sbjct: 1757 AWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKR 1816
Query: 233 KEREDGKEDEGGN------EEEAGKEKEDLKEEEE 261
+ + E+ N ++ +EK++L +E+E
Sbjct: 1817 ERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKE 1851
Score = 39.7 bits (91), Expect = 0.003
Identities = 46/187 (24%), Positives = 84/187 (44%), Gaps = 16/187 (8%)
Query: 95 KEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGE-AGKEDKDEKG 153
KEI + +E+ + K G K +V + + ++E D +EE E A E+K K
Sbjct: 1385 KEISKKEEKKTFQKSPKQGRKAVQKERKVGKIKREMTKEERDMSEEVEEMATLEEKVVK- 1443
Query: 154 EEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGK---E 210
++GK E +D KK D E + GE K + KE + + E
Sbjct: 1444 -QEGKLVMI-----ERTPSWQDWKKAWD-----EWKQVHGETRKSWKAWKEEWEKRLLQE 1492
Query: 211 NEDGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKE 270
E + G+K ++ ++ED+K + + + N + +++ K+EEE E+E+
Sbjct: 1493 EEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEEEVSR 1552
Query: 271 DDGKKEE 277
+ +KE+
Sbjct: 1553 EGEEKEQ 1559
Score = 39.3 bits (90), Expect = 0.004
Identities = 45/228 (19%), Positives = 103/228 (45%), Gaps = 36/228 (15%)
Query: 73 EEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAE---VKNEE-- 127
++ + ++ K G +A E+++ ++K E ++ + E +E E VK E
Sbjct: 1393 KKTFQKSPKQGR----KAVQKERKVGKIKREMTKEERDMSEEVEEMATLEEKVVKQEGKL 1448
Query: 128 ---------EDQKEDEEDQNEEKGEAGKEDKDEKGEEDGK---EDKNGNEKGEDAKEKED 175
+D K+ ++ + GE K K K E + + E++ ++ GE +E+
Sbjct: 1449 VMIERTPSWQDWKKAWDEWKQVHGETRKSWKAWKEEWEKRLLQEEEKLHQAGEKLSPEEE 1508
Query: 176 GKKGEDGKGNGEDGKE--------KGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVK 227
+ ED K E+ K+ K ++++ +++ + T + + + +G+EK + +
Sbjct: 1509 MLQ-EDKKLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRH 1567
Query: 228 VKEDEK------EREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIK 269
++E+ K +R ++ E + +E+E L +EE ++E K
Sbjct: 1568 IQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERK 1615
Score = 38.1 bits (87), Expect = 0.009
Identities = 54/257 (21%), Positives = 108/257 (42%), Gaps = 21/257 (8%)
Query: 37 KRTSSSRKMKT--KSDMMEENIDTSAQAVAETKQEAVVEE-DYNENAKNGEAKITEAPAS 93
K S + KT KS + V + K+E EE D +E + +
Sbjct: 1385 KEISKKEEKKTFQKSPKQGRKAVQKERKVGKIKREMTKEERDMSEEVEEMATLEEKVVKQ 1444
Query: 94 EKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEED---QNEEK-GEAGKE-- 147
E ++V ++ +K ++ + V E + + KE+ E Q EEK +AG++
Sbjct: 1445 EGKLVMIERTPSWQDWKKAWDEWKQVHGETRKSWKAWKEEWEKRLLQEEEKLHQAGEKLS 1504
Query: 148 DKDEKGEEDGK----EDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRK 203
++E +ED K E K E +K KE K E+ E+ +GE+++++ +
Sbjct: 1505 PEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEE 1564
Query: 204 ETGDGKENEDGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGK 263
+ +E++ + + + + +E+ K ++ EE+ +E+ L +EE
Sbjct: 1565 QRHIQEEHKWARIHRKRARAEKKRAQEERKLAQE--------EEKLAQEERQLAQEERKL 1616
Query: 264 EEDEIKEDDGKKEEPQS 280
+ +K +E Q+
Sbjct: 1617 AQAYVKITQDDREMAQA 1633
>gi|192807336 arsenate resistance protein 2 isoform e [Homo sapiens]
Length = 871
Score = 81.3 bits (199), Expect = 9e-16
Identities = 49/141 (34%), Positives = 78/141 (55%), Gaps = 8/141 (5%)
Query: 130 QKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDG 189
++E+EE+Q + GE K+++ G G ++ N+K E +KEDGK+ E+ N +D
Sbjct: 269 EQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDE---KKEDGKQAENDSSN-DDK 324
Query: 190 KEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDV----KVKEDEKEREDGKEDEGGN 245
+K E + ++E++KE + + + K++ K G D V E E E E G+ +E
Sbjct: 325 TKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKE 384
Query: 246 EEEAGKEKEDLKEEEEGKEED 266
E EA KEKE KEEE K +D
Sbjct: 385 EAEALKEKEKPKEEEWEKPKD 405
Score = 58.9 bits (141), Expect = 5e-09
Identities = 46/163 (28%), Positives = 83/163 (50%), Gaps = 22/163 (13%)
Query: 93 SEKEIVEVKEENIEDATEKGGE--KKE-----AVAAEVKNEEEDQKEDEEDQNEEKGEAG 145
+E ++ +++E E+ K GE KKE A + + + D+ E +ED + + ++
Sbjct: 261 TENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSS 320
Query: 146 KEDKDEKGEEDGKEDKNGNEKGEDA-KEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKE 204
+DK +K E DG ++ EK ED+ KE + K + K +G+D ++G + E
Sbjct: 321 NDDKTKKSEGDGDKE----EKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESE----- 371
Query: 205 TGDGKENEDGKEKGDKKEGKDVKVKEDEKERE-DGKEDEGGNE 246
E+E G+ + +K+E + +K KE KE E + +D G E
Sbjct: 372 ----SESESGQAEEEKEEAEALKEKEKPKEEEWEKPKDAAGLE 410
Score = 38.5 bits (88), Expect = 0.007
Identities = 32/148 (21%), Positives = 58/148 (39%), Gaps = 4/148 (2%)
Query: 63 VAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAE 122
+ E ++E E +K E + + K+E ED + + +
Sbjct: 267 ILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTK 326
Query: 123 VKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDG 182
+ D++E +ED + EA K K + G + + E E E G + E+
Sbjct: 327 KSEGDGDKEEKKEDSEK---EAKKSSKKRNRKHSGDDSFDEGSVSESESESESG-QAEEE 382
Query: 183 KGNGEDGKEKGEDEKEEEDRKETGDGKE 210
K E KEK + ++EE ++ + G E
Sbjct: 383 KEEAEALKEKEKPKEEEWEKPKDAAGLE 410
Score = 28.9 bits (63), Expect = 5.3
Identities = 20/110 (18%), Positives = 52/110 (47%), Gaps = 2/110 (1%)
Query: 48 KSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIED 107
K++ +E + QA ++ + ++ + K + + +E A + ++ + +D
Sbjct: 301 KTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDD 360
Query: 108 ATEKGGEKKEAVAAEVKNEEEDQKEDE--EDQNEEKGEAGKEDKDEKGEE 155
+ ++G + +E EE+++E E +++ + K E ++ KD G E
Sbjct: 361 SFDEGSVSESESESESGQAEEEKEEAEALKEKEKPKEEEWEKPKDAAGLE 410
>gi|192807332 arsenate resistance protein 2 isoform c [Homo sapiens]
Length = 875
Score = 81.3 bits (199), Expect = 9e-16
Identities = 49/141 (34%), Positives = 78/141 (55%), Gaps = 8/141 (5%)
Query: 130 QKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDG 189
++E+EE+Q + GE K+++ G G ++ N+K E +KEDGK+ E+ N +D
Sbjct: 269 EQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDE---KKEDGKQAENDSSN-DDK 324
Query: 190 KEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDV----KVKEDEKEREDGKEDEGGN 245
+K E + ++E++KE + + + K++ K G D V E E E E G+ +E
Sbjct: 325 TKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKE 384
Query: 246 EEEAGKEKEDLKEEEEGKEED 266
E EA KEKE KEEE K +D
Sbjct: 385 EAEALKEKEKPKEEEWEKPKD 405
Score = 58.9 bits (141), Expect = 5e-09
Identities = 46/163 (28%), Positives = 83/163 (50%), Gaps = 22/163 (13%)
Query: 93 SEKEIVEVKEENIEDATEKGGE--KKE-----AVAAEVKNEEEDQKEDEEDQNEEKGEAG 145
+E ++ +++E E+ K GE KKE A + + + D+ E +ED + + ++
Sbjct: 261 TENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSS 320
Query: 146 KEDKDEKGEEDGKEDKNGNEKGEDA-KEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKE 204
+DK +K E DG ++ EK ED+ KE + K + K +G+D ++G + E
Sbjct: 321 NDDKTKKSEGDGDKE----EKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESE----- 371
Query: 205 TGDGKENEDGKEKGDKKEGKDVKVKEDEKERE-DGKEDEGGNE 246
E+E G+ + +K+E + +K KE KE E + +D G E
Sbjct: 372 ----SESESGQAEEEKEEAEALKEKEKPKEEEWEKPKDAAGLE 410
Score = 38.5 bits (88), Expect = 0.007
Identities = 32/148 (21%), Positives = 58/148 (39%), Gaps = 4/148 (2%)
Query: 63 VAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAE 122
+ E ++E E +K E + + K+E ED + + +
Sbjct: 267 ILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTK 326
Query: 123 VKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDG 182
+ D++E +ED + EA K K + G + + E E E G + E+
Sbjct: 327 KSEGDGDKEEKKEDSEK---EAKKSSKKRNRKHSGDDSFDEGSVSESESESESG-QAEEE 382
Query: 183 KGNGEDGKEKGEDEKEEEDRKETGDGKE 210
K E KEK + ++EE ++ + G E
Sbjct: 383 KEEAEALKEKEKPKEEEWEKPKDAAGLE 410
Score = 28.9 bits (63), Expect = 5.3
Identities = 20/110 (18%), Positives = 52/110 (47%), Gaps = 2/110 (1%)
Query: 48 KSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIED 107
K++ +E + QA ++ + ++ + K + + +E A + ++ + +D
Sbjct: 301 KTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDD 360
Query: 108 ATEKGGEKKEAVAAEVKNEEEDQKEDE--EDQNEEKGEAGKEDKDEKGEE 155
+ ++G + +E EE+++E E +++ + K E ++ KD G E
Sbjct: 361 SFDEGSVSESESESESGQAEEEKEEAEALKEKEKPKEEEWEKPKDAAGLE 410
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 80.9 bits (198), Expect = 1e-15
Identities = 69/310 (22%), Positives = 145/310 (46%), Gaps = 47/310 (15%)
Query: 11 DMRQEPKRRSARLSAMLVPVTPEVKPKRTSSSRKM-----KTKSDMMEENIDTSAQAVAE 65
D +++ +R S++ A++V RTS+ RK + SD+ +++ ++ + ++
Sbjct: 1126 DNKKKKQRTSSKKKAVIVKEKKR-NSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSD 1184
Query: 66 TKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVK- 124
++ V E+ ++ G + + A K + +++ +D + K+ + E+K
Sbjct: 1185 EQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKA 1244
Query: 125 --NEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKE-------- 174
+ +ED D+E + E K GK++++ G+E+ K N + + K+
Sbjct: 1245 NLSSDEDGSSDDEPE-EGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLL 1303
Query: 175 -------DGKKGEDGKGNGEDGKE-KGE-------DEKEEEDRKETGDGKE--NEDGKEK 217
DG+ GE+ K ++ KE KG ++ E+ D +E+G +E + +++
Sbjct: 1304 RHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQR 1363
Query: 218 GDKKEGKDVKVKEDE------------KEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEE 265
+ K +++E++ K +ED + N EE +EKE+ +EEEE +EE
Sbjct: 1364 PRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEE 1423
Query: 266 DEIKEDDGKK 275
+E E+D K
Sbjct: 1424 EEEDENDDSK 1433
Score = 63.9 bits (154), Expect = 1e-10
Identities = 51/240 (21%), Positives = 107/240 (44%), Gaps = 11/240 (4%)
Query: 32 PEVKPKRTSSSRKMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKITEAP 91
PE KRT + + + +++ + + +E ++ Y + +++
Sbjct: 1258 PEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKP----RYRHRLLRHKLTVSDGE 1313
Query: 92 ASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKED-EEDQNEEKGEAGKEDKD 150
+ E++ + KE E G + V++E + + Q+ E+ +E + E +
Sbjct: 1314 SGEEKKTKPKEHK-----EVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRS 1368
Query: 151 EKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKE 210
K E + ++ +K + + K + K N E+ +E+ E+E+EEE+ +E + E
Sbjct: 1369 AKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDE 1428
Query: 211 NEDGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKE 270
N+D K G K K K+ +D+K R + + EE + E +E E+ +E EI++
Sbjct: 1429 NDDSKSPG-KGRKKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLREVIEIED 1487
Score = 43.5 bits (101), Expect = 2e-04
Identities = 67/397 (16%), Positives = 139/397 (35%), Gaps = 130/397 (32%)
Query: 3 KRKAAGQGDMRQEPKRRSARLSAMLVPVTPEVKPKRTSSSRKMKTKS-DMMEENIDTSAQ 61
K++A+ D + + +++ V E K K S+ +KTK+ +++ + A+
Sbjct: 873 KQQASASTDGVDKLSGKEQSFTSLEVRKVAETKEK----SKHLKTKTCKKVQDGLSDIAE 928
Query: 62 AVAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKE--ENIEDATEK-------- 111
+ Q ED + +K G + + +K+++++++ E+ D TEK
Sbjct: 929 KFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEIC 988
Query: 112 --------------GGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEA--GKEDKDEKGEE 155
GEKK + ++++D+ D +++ KG++ EDK K
Sbjct: 989 HFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGA 1048
Query: 156 DGKEDKNGNEKGEDAKEKED---------------------------------------- 175
G+E K G+ +++++D
Sbjct: 1049 YGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNT 1108
Query: 176 -----GKKGEDGKGNGEDGKEK-----------------------------------GED 195
G D + + ED K+K
Sbjct: 1109 KEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSS 1168
Query: 196 EKEEEDRKETGDGKENEDG-----------------KEKGDKKEGKDVKVKEDEKEREDG 238
+ E++D+ G+G +E + GD+ K V V D+ + ++
Sbjct: 1169 DIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDND 1228
Query: 239 KEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDDGKK 275
E+ + + K +L +E+G +DE ++GKK
Sbjct: 1229 PENRIAKKMLLEEIKANLSSDEDGSSDDE--PEEGKK 1263
Score = 43.5 bits (101), Expect = 2e-04
Identities = 53/236 (22%), Positives = 97/236 (41%), Gaps = 41/236 (17%)
Query: 86 KITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAG 145
K+ E K + + ++D EK + E+D+K+ ++ E+K +
Sbjct: 900 KVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSD 959
Query: 146 KEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKG----EDGKGNGE-------DGKEKGE 194
+ K K E+ + +G EK + +E KG ++G +GE D K +
Sbjct: 960 FKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKK 1019
Query: 195 DEKEEEDRKETGDG--------KENEDGKEKGDKKE----GKDVKVKED----EKEREDG 238
DE + K TG G K++++G +KK GK + ++D + E+
Sbjct: 1020 DELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSM 1079
Query: 239 KEDEGGNEEEAGK-----------EKEDLKEEEEG---KEEDEIKEDDGKKEEPQS 280
KED + ++ K K + KE + G + +E ED+ KK++ S
Sbjct: 1080 KEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTS 1135
Score = 42.0 bits (97), Expect = 6e-04
Identities = 48/186 (25%), Positives = 69/186 (37%), Gaps = 23/186 (12%)
Query: 67 KQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEK--GGEKKEAVAAEVK 124
K +EED N + +A E E ++++ K E EK EKK+ +E K
Sbjct: 366 KAHLALEEDLNSEFRAMDAVNKEKNTKEHKVIDAKFETKARKGEKPCALEKKDISKSEAK 425
Query: 125 -------NEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEK----------- 166
+E Q E+Q K G+ K ++ EE E N +E
Sbjct: 426 LSRKQVDSEHMHQNVPTEEQRTNKSTGGEHKKSDRKEEPQYEPANTSEDLDMDIVSVPSS 485
Query: 167 -GEDAKEK-EDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDG-KEKGDKKEG 223
ED E E + + + DG E E E K K+N G K K K
Sbjct: 486 VPEDIFENLETAMEVQSSVDHQGDGSSGTEQEVESSSVKLNISSKDNRGGIKSKTTAKVT 545
Query: 224 KDVKVK 229
K++ VK
Sbjct: 546 KELYVK 551
Score = 41.6 bits (96), Expect = 8e-04
Identities = 57/275 (20%), Positives = 115/275 (41%), Gaps = 31/275 (11%)
Query: 11 DMRQEPKRRSARLSAMLVPVTPEVKPKRTSSSRKMKTKSDMMEENIDTSAQAVAETKQEA 70
+++ K +AR + +P T + K K + +N+ TS + ++ +
Sbjct: 786 EIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSK-KGMDNQGHKNLKTSQEGSSDDAERK 844
Query: 71 VVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEK-GGEKKEAVAAEVKNEEED 129
E ++ + T ++ + + D +K G+++ + EV+ E
Sbjct: 845 QERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAET 904
Query: 130 QKEDEEDQNE--EKGEAGKED------KDEKGEEDGKEDKNGNEKG-EDAKEKEDGKKG- 179
+++ + + + +K + G D K ++ +E ++DK ++KG E+ K+ D KK
Sbjct: 905 KEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKV 964
Query: 180 ---EDGKGNGEDGKEKGEDEKE----EEDRKETGDGKENEDGKEKGDKKEGKDVKVKE-- 230
E + DG EK + +E + K+ +G DG++K K K K K+
Sbjct: 965 IKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNG--TTDGEKKSKKIRDKTSKKKDEL 1022
Query: 231 -DEKEREDGKEDEGGNEEEA-------GKEKEDLK 257
D E+ GK D + E+ G+EK+ K
Sbjct: 1023 SDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCK 1057
Score = 33.5 bits (75), Expect = 0.22
Identities = 43/224 (19%), Positives = 81/224 (36%), Gaps = 41/224 (18%)
Query: 73 EEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKE 132
+E+ NE K E + P +K+ K + + A + K + ++E DQ
Sbjct: 640 DEECNETVK--EKQKLSVPVRKKD----KRNSSDSAIDN--PKPNKLPKSKQSETVDQNS 691
Query: 133 DEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGN--------EKGEDAKEKEDGKKGEDGKG 184
D ++ E + + D E + + G+D K K K G
Sbjct: 692 DSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSD 751
Query: 185 ----NGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEG------------KDVKV 228
G+ K +K+ + + E+ + + + K K G KD
Sbjct: 752 FDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDS 811
Query: 229 KEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDD 272
EDEK + G +++G ++LK +EG +D ++ +
Sbjct: 812 SEDEKHSKKGMDNQG---------HKNLKTSQEGSSDDAERKQE 846
Score = 30.8 bits (68), Expect = 1.4
Identities = 18/75 (24%), Positives = 31/75 (41%)
Query: 139 EEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKE 198
E KG ++ DE D E + K+K+ GKKG+ + G + + +
Sbjct: 1859 ENKGYFDEDSMDEFIASDSDETSMSLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIK 1918
Query: 199 EEDRKETGDGKENED 213
+ + G G+ N D
Sbjct: 1919 VWNSRSRGGGEGNVD 1933
Score = 28.5 bits (62), Expect = 6.9
Identities = 17/108 (15%), Positives = 44/108 (40%)
Query: 41 SSRKMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEV 100
S K+ T + + + S++ ET + + N + +G ++ + KE
Sbjct: 7 SESKLNTLVQKLHDFLAHSSEESEETSSPPRLAMNQNTDKISGSGSNSDMMENSKEEGTS 66
Query: 101 KEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKED 148
E + + ++K ++ + ++++ D+E NE+ E+
Sbjct: 67 SSEKSKSSGSSRSKRKPSIVTKYVESDDEKPLDDETVNEDASNENSEN 114
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 80.9 bits (198), Expect = 1e-15
Identities = 69/310 (22%), Positives = 145/310 (46%), Gaps = 47/310 (15%)
Query: 11 DMRQEPKRRSARLSAMLVPVTPEVKPKRTSSSRKM-----KTKSDMMEENIDTSAQAVAE 65
D +++ +R S++ A++V RTS+ RK + SD+ +++ ++ + ++
Sbjct: 1164 DNKKKKQRTSSKKKAVIVKEKKR-NSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSD 1222
Query: 66 TKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVK- 124
++ V E+ ++ G + + A K + +++ +D + K+ + E+K
Sbjct: 1223 EQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKA 1282
Query: 125 --NEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKE-------- 174
+ +ED D+E + E K GK++++ G+E+ K N + + K+
Sbjct: 1283 NLSSDEDGSSDDEPE-EGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLL 1341
Query: 175 -------DGKKGEDGKGNGEDGKE-KGE-------DEKEEEDRKETGDGKE--NEDGKEK 217
DG+ GE+ K ++ KE KG ++ E+ D +E+G +E + +++
Sbjct: 1342 RHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQR 1401
Query: 218 GDKKEGKDVKVKEDE------------KEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEE 265
+ K +++E++ K +ED + N EE +EKE+ +EEEE +EE
Sbjct: 1402 PRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEE 1461
Query: 266 DEIKEDDGKK 275
+E E+D K
Sbjct: 1462 EEEDENDDSK 1471
Score = 63.9 bits (154), Expect = 1e-10
Identities = 51/240 (21%), Positives = 107/240 (44%), Gaps = 11/240 (4%)
Query: 32 PEVKPKRTSSSRKMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKITEAP 91
PE KRT + + + +++ + + +E ++ Y + +++
Sbjct: 1296 PEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKP----RYRHRLLRHKLTVSDGE 1351
Query: 92 ASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKED-EEDQNEEKGEAGKEDKD 150
+ E++ + KE E G + V++E + + Q+ E+ +E + E +
Sbjct: 1352 SGEEKKTKPKEHK-----EVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRS 1406
Query: 151 EKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKE 210
K E + ++ +K + + K + K N E+ +E+ E+E+EEE+ +E + E
Sbjct: 1407 AKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDE 1466
Query: 211 NEDGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKE 270
N+D K G K K K+ +D+K R + + EE + E +E E+ +E EI++
Sbjct: 1467 NDDSKSPG-KGRKKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLREVIEIED 1525
Score = 43.5 bits (101), Expect = 2e-04
Identities = 67/397 (16%), Positives = 139/397 (35%), Gaps = 130/397 (32%)
Query: 3 KRKAAGQGDMRQEPKRRSARLSAMLVPVTPEVKPKRTSSSRKMKTKS-DMMEENIDTSAQ 61
K++A+ D + + +++ V E K K S+ +KTK+ +++ + A+
Sbjct: 911 KQQASASTDGVDKLSGKEQSFTSLEVRKVAETKEK----SKHLKTKTCKKVQDGLSDIAE 966
Query: 62 AVAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKE--ENIEDATEK-------- 111
+ Q ED + +K G + + +K+++++++ E+ D TEK
Sbjct: 967 KFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEIC 1026
Query: 112 --------------GGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEA--GKEDKDEKGEE 155
GEKK + ++++D+ D +++ KG++ EDK K
Sbjct: 1027 HFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGA 1086
Query: 156 DGKEDKNGNEKGEDAKEKED---------------------------------------- 175
G+E K G+ +++++D
Sbjct: 1087 YGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNT 1146
Query: 176 -----GKKGEDGKGNGEDGKEK-----------------------------------GED 195
G D + + ED K+K
Sbjct: 1147 KEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSS 1206
Query: 196 EKEEEDRKETGDGKENEDG-----------------KEKGDKKEGKDVKVKEDEKEREDG 238
+ E++D+ G+G +E + GD+ K V V D+ + ++
Sbjct: 1207 DIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDND 1266
Query: 239 KEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDDGKK 275
E+ + + K +L +E+G +DE ++GKK
Sbjct: 1267 PENRIAKKMLLEEIKANLSSDEDGSSDDE--PEEGKK 1301
Score = 43.5 bits (101), Expect = 2e-04
Identities = 53/236 (22%), Positives = 97/236 (41%), Gaps = 41/236 (17%)
Query: 86 KITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAG 145
K+ E K + + ++D EK + E+D+K+ ++ E+K +
Sbjct: 938 KVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSD 997
Query: 146 KEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKG----EDGKGNGE-------DGKEKGE 194
+ K K E+ + +G EK + +E KG ++G +GE D K +
Sbjct: 998 FKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKK 1057
Query: 195 DEKEEEDRKETGDG--------KENEDGKEKGDKKE----GKDVKVKED----EKEREDG 238
DE + K TG G K++++G +KK GK + ++D + E+
Sbjct: 1058 DELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSM 1117
Query: 239 KEDEGGNEEEAGK-----------EKEDLKEEEEG---KEEDEIKEDDGKKEEPQS 280
KED + ++ K K + KE + G + +E ED+ KK++ S
Sbjct: 1118 KEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTS 1173
Score = 42.0 bits (97), Expect = 6e-04
Identities = 48/186 (25%), Positives = 69/186 (37%), Gaps = 23/186 (12%)
Query: 67 KQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEK--GGEKKEAVAAEVK 124
K +EED N + +A E E ++++ K E EK EKK+ +E K
Sbjct: 404 KAHLALEEDLNSEFRAMDAVNKEKNTKEHKVIDAKFETKARKGEKPCALEKKDISKSEAK 463
Query: 125 -------NEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEK----------- 166
+E Q E+Q K G+ K ++ EE E N +E
Sbjct: 464 LSRKQVDSEHMHQNVPTEEQRTNKSTGGEHKKSDRKEEPQYEPANTSEDLDMDIVSVPSS 523
Query: 167 -GEDAKEK-EDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDG-KEKGDKKEG 223
ED E E + + + DG E E E K K+N G K K K
Sbjct: 524 VPEDIFENLETAMEVQSSVDHQGDGSSGTEQEVESSSVKLNISSKDNRGGIKSKTTAKVT 583
Query: 224 KDVKVK 229
K++ VK
Sbjct: 584 KELYVK 589
Score = 41.6 bits (96), Expect = 8e-04
Identities = 57/275 (20%), Positives = 115/275 (41%), Gaps = 31/275 (11%)
Query: 11 DMRQEPKRRSARLSAMLVPVTPEVKPKRTSSSRKMKTKSDMMEENIDTSAQAVAETKQEA 70
+++ K +AR + +P T + K K + +N+ TS + ++ +
Sbjct: 824 EIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSK-KGMDNQGHKNLKTSQEGSSDDAERK 882
Query: 71 VVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEK-GGEKKEAVAAEVKNEEED 129
E ++ + T ++ + + D +K G+++ + EV+ E
Sbjct: 883 QERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAET 942
Query: 130 QKEDEEDQNE--EKGEAGKED------KDEKGEEDGKEDKNGNEKG-EDAKEKEDGKKG- 179
+++ + + + +K + G D K ++ +E ++DK ++KG E+ K+ D KK
Sbjct: 943 KEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKV 1002
Query: 180 ---EDGKGNGEDGKEKGEDEKE----EEDRKETGDGKENEDGKEKGDKKEGKDVKVKE-- 230
E + DG EK + +E + K+ +G DG++K K K K K+
Sbjct: 1003 IKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNG--TTDGEKKSKKIRDKTSKKKDEL 1060
Query: 231 -DEKEREDGKEDEGGNEEEA-------GKEKEDLK 257
D E+ GK D + E+ G+EK+ K
Sbjct: 1061 SDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCK 1095
Score = 33.5 bits (75), Expect = 0.22
Identities = 29/158 (18%), Positives = 62/158 (39%), Gaps = 16/158 (10%)
Query: 41 SSRKMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEV 100
S K+ T + + + S++ ET + + N + +G ++ + KE
Sbjct: 7 SESKLNTLVQKLHDFLAHSSEESEETSSPPRLAMNQNTDKISGSGSNSDMMENSKEEGTS 66
Query: 101 KEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKED------------ 148
E + + ++K ++ + ++++ D+E NE+ E+
Sbjct: 67 SSEKSKSSGSSRSKRKPSIVTKYVESDDEKPLDDETVNEDASNENSENDITMQSLPKGTV 126
Query: 149 --KDEKGEEDGKEDKNGNEKGEDAKEKEDG--KKGEDG 182
+ E + K+D G E +K K + K+GEDG
Sbjct: 127 IVQPEPVLNEDKDDFKGPEFRSRSKMKTENLKKRGEDG 164
Score = 33.5 bits (75), Expect = 0.22
Identities = 43/224 (19%), Positives = 81/224 (36%), Gaps = 41/224 (18%)
Query: 73 EEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKE 132
+E+ NE K E + P +K+ K + + A + K + ++E DQ
Sbjct: 678 DEECNETVK--EKQKLSVPVRKKD----KRNSSDSAIDN--PKPNKLPKSKQSETVDQNS 729
Query: 133 DEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGN--------EKGEDAKEKEDGKKGEDGKG 184
D ++ E + + D E + + G+D K K K G
Sbjct: 730 DSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSD 789
Query: 185 ----NGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEG------------KDVKV 228
G+ K +K+ + + E+ + + + K K G KD
Sbjct: 790 FDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDS 849
Query: 229 KEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDD 272
EDEK + G +++G ++LK +EG +D ++ +
Sbjct: 850 SEDEKHSKKGMDNQG---------HKNLKTSQEGSSDDAERKQE 884
Score = 30.8 bits (68), Expect = 1.4
Identities = 18/75 (24%), Positives = 31/75 (41%)
Query: 139 EEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKE 198
E KG ++ DE D E + K+K+ GKKG+ + G + + +
Sbjct: 1897 ENKGYFDEDSMDEFIASDSDETSMSLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIK 1956
Query: 199 EEDRKETGDGKENED 213
+ + G G+ N D
Sbjct: 1957 VWNSRSRGGGEGNVD 1971
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 79.7 bits (195), Expect = 3e-15
Identities = 80/298 (26%), Positives = 131/298 (43%), Gaps = 37/298 (12%)
Query: 8 GQGDMRQEPKRRSARLSAMLVPVTPEVKPKRTSSSRKMKTKSDMMEENIDTSAQA----- 62
G+ + + P + PV + K S + K KS + + ++ A++
Sbjct: 626 GKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKS 685
Query: 63 -VAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEK---KEA 118
V E K +A V + E + E ++ EAP EK VE KEE +D EK + KE
Sbjct: 686 PVEEAKSKAEVGK--GEQKEEEEKEVKEAPKEEK--VEKKEEKPKDVPEKKKAESPVKEE 741
Query: 119 VAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKD-EKGEEDGKEDKNGNEKGEDAKEKEDGK 177
AEV + K E + +E+G+ +++K+ EK +G ++ G++KG KED
Sbjct: 742 AVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKED-- 799
Query: 178 KGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDG-------------KEKGDKKEGK 224
+G+ +G++E E+E KE G G+E E G K+ GDK E K
Sbjct: 800 -------IAVNGEVEGKEEVEQE-TKEKGSGREEEKGVVTNGLDLSPADEKKGGDKSEEK 851
Query: 225 DVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDDGKKEEPQSIV 282
V K EK +G + ++ + ++E EE EE + +K +IV
Sbjct: 852 VVVTKTVEKITSEGGDGATKYITKSVTVTQKVEEHEETFEEKLVSTKKVEKVTSHAIV 909
Score = 75.9 bits (185), Expect = 4e-14
Identities = 69/249 (27%), Positives = 120/249 (48%), Gaps = 15/249 (6%)
Query: 35 KPKRTSSSRKMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKITEAPASE 94
+P T SS+ K K + + + + V E +E VE++ +E + A E S
Sbjct: 427 RPPITISSKIQKPKVEAPK--LKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSM 484
Query: 95 KEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGE 154
KE + E E+ E E+ A + VK + KE+E ++ EE+G+ +E++DE +
Sbjct: 485 KEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAK 544
Query: 155 EDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDG 214
D E+ G+EK E + EKE+G++ E+G+ + E E EE + KE + K E
Sbjct: 545 SDQAEE-GGSEK-EGSSEKEEGEQ--------EEGETEAEAEGEEAEAKE--EKKVEEKS 592
Query: 215 KEKGDKKE-GKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDDG 273
+E K+E D KV++ EK + + + ++ K ++E+ + E+ G
Sbjct: 593 EEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKG 652
Query: 274 KKEEPQSIV 282
K P+S V
Sbjct: 653 KSPVPKSPV 661
Score = 75.1 bits (183), Expect = 6e-14
Identities = 96/359 (26%), Positives = 148/359 (41%), Gaps = 89/359 (24%)
Query: 1 MPKRKAAGQGDMRQEPKRRSARLSAMLVPV---TPEVKPKRTSSSRKMKTKSDMMEENID 57
M + K + +EP+ ++A PV PEVK + K + + EE +
Sbjct: 484 MKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGE-----KEEEEGQEEEEE 538
Query: 58 TSAQAVAETKQEAVVEEDYNENAKNGEAKITEAPA-SEKEIVEVKEENIEDATEKGGEKK 116
A ++ +E E++ + + GE + E A +E E E KEE +K EK
Sbjct: 539 EDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEE------KKVEEKS 592
Query: 117 EAVA--------AEVKNEEEDQKEDEEDQNEEKGEA--GKEDKDEKG---------EEDG 157
E VA A+V+ E+ + + EEKG++ K +EKG EE G
Sbjct: 593 EEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKG 652
Query: 158 KE---DKNGNEKG----------------------EDAKEKEDGKKGEDGKGNGEDGKEK 192
K EKG E+AK K + KGE + ++ KE
Sbjct: 653 KSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEA 712
Query: 193 GEDEKEEEDRKETGDGKENEDGK----------------------EKGDKKEGKDVKVKE 230
++EK E+ ++ D E + + EK K+EGK ++ +E
Sbjct: 713 PKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQ-QE 771
Query: 231 DEKER---EDGKEDEGGNEEEAGKEKEDL--KEEEEGKE--EDEIKEDDGKKEEPQSIV 282
EKE+ E G E+EG ++ G KED+ E EGKE E E KE +EE + +V
Sbjct: 772 KEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGSGREEEKGVV 830
Score = 70.1 bits (170), Expect = 2e-12
Identities = 66/272 (24%), Positives = 117/272 (43%), Gaps = 27/272 (9%)
Query: 33 EVKPKRTSSSRKMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKITEAPA 92
+V+ +++ + ++ + ++ + AE K+E E+ AK K T
Sbjct: 461 KVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEV 520
Query: 93 SEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEK 152
E+E + +EE E+ E+ K A E +E+E E EE + EE G+ + + +
Sbjct: 521 KEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEE----GETEAEAE 576
Query: 153 GEE-DGKEDKNGNEKGEDAKEKE----DGKKGEDGKGNGEDGK----EKG-----EDEKE 198
GEE + KE+K EK E+ KE D K + K K EKG + E
Sbjct: 577 GEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVE 636
Query: 199 EEDRKETGDGKENEDGK---------EKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEA 249
E+ + E GK EKG K ++ + +E ++ E
Sbjct: 637 EKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEV 696
Query: 250 GKEKEDLKEEEEGKEEDEIKEDDGKKEEPQSI 281
GK ++ +EE+E KE + ++ + K+E+P+ +
Sbjct: 697 GKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDV 728
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 79.7 bits (195), Expect = 3e-15
Identities = 80/298 (26%), Positives = 131/298 (43%), Gaps = 37/298 (12%)
Query: 8 GQGDMRQEPKRRSARLSAMLVPVTPEVKPKRTSSSRKMKTKSDMMEENIDTSAQA----- 62
G+ + + P + PV + K S + K KS + + ++ A++
Sbjct: 250 GKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKS 309
Query: 63 -VAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEK---KEA 118
V E K +A V + E + E ++ EAP EK VE KEE +D EK + KE
Sbjct: 310 PVEEAKSKAEVGK--GEQKEEEEKEVKEAPKEEK--VEKKEEKPKDVPEKKKAESPVKEE 365
Query: 119 VAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKD-EKGEEDGKEDKNGNEKGEDAKEKEDGK 177
AEV + K E + +E+G+ +++K+ EK +G ++ G++KG KED
Sbjct: 366 AVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKED-- 423
Query: 178 KGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDG-------------KEKGDKKEGK 224
+G+ +G++E E+E KE G G+E E G K+ GDK E K
Sbjct: 424 -------IAVNGEVEGKEEVEQE-TKEKGSGREEEKGVVTNGLDLSPADEKKGGDKSEEK 475
Query: 225 DVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDDGKKEEPQSIV 282
V K EK +G + ++ + ++E EE EE + +K +IV
Sbjct: 476 VVVTKTVEKITSEGGDGATKYITKSVTVTQKVEEHEETFEEKLVSTKKVEKVTSHAIV 533
Score = 75.9 bits (185), Expect = 4e-14
Identities = 69/249 (27%), Positives = 120/249 (48%), Gaps = 15/249 (6%)
Query: 35 KPKRTSSSRKMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKITEAPASE 94
+P T SS+ K K + + + + V E +E VE++ +E + A E S
Sbjct: 51 RPPITISSKIQKPKVEAPK--LKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSM 108
Query: 95 KEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGE 154
KE + E E+ E E+ A + VK + KE+E ++ EE+G+ +E++DE +
Sbjct: 109 KEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAK 168
Query: 155 EDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDG 214
D E+ G+EK E + EKE+G++ E+G+ + E E EE + KE + K E
Sbjct: 169 SDQAEE-GGSEK-EGSSEKEEGEQ--------EEGETEAEAEGEEAEAKE--EKKVEEKS 216
Query: 215 KEKGDKKE-GKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDDG 273
+E K+E D KV++ EK + + + ++ K ++E+ + E+ G
Sbjct: 217 EEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKG 276
Query: 274 KKEEPQSIV 282
K P+S V
Sbjct: 277 KSPVPKSPV 285
Score = 75.1 bits (183), Expect = 6e-14
Identities = 96/359 (26%), Positives = 148/359 (41%), Gaps = 89/359 (24%)
Query: 1 MPKRKAAGQGDMRQEPKRRSARLSAMLVPV---TPEVKPKRTSSSRKMKTKSDMMEENID 57
M + K + +EP+ ++A PV PEVK + K + + EE +
Sbjct: 108 MKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGE-----KEEEEGQEEEEE 162
Query: 58 TSAQAVAETKQEAVVEEDYNENAKNGEAKITEAPA-SEKEIVEVKEENIEDATEKGGEKK 116
A ++ +E E++ + + GE + E A +E E E KEE +K EK
Sbjct: 163 EDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEE------KKVEEKS 216
Query: 117 EAVA--------AEVKNEEEDQKEDEEDQNEEKGEA--GKEDKDEKG---------EEDG 157
E VA A+V+ E+ + + EEKG++ K +EKG EE G
Sbjct: 217 EEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKG 276
Query: 158 KE---DKNGNEKG----------------------EDAKEKEDGKKGEDGKGNGEDGKEK 192
K EKG E+AK K + KGE + ++ KE
Sbjct: 277 KSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEA 336
Query: 193 GEDEKEEEDRKETGDGKENEDGK----------------------EKGDKKEGKDVKVKE 230
++EK E+ ++ D E + + EK K+EGK ++ +E
Sbjct: 337 PKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQ-QE 395
Query: 231 DEKER---EDGKEDEGGNEEEAGKEKEDL--KEEEEGKE--EDEIKEDDGKKEEPQSIV 282
EKE+ E G E+EG ++ G KED+ E EGKE E E KE +EE + +V
Sbjct: 396 KEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGSGREEEKGVV 454
Score = 70.1 bits (170), Expect = 2e-12
Identities = 66/272 (24%), Positives = 117/272 (43%), Gaps = 27/272 (9%)
Query: 33 EVKPKRTSSSRKMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKITEAPA 92
+V+ +++ + ++ + ++ + AE K+E E+ AK K T
Sbjct: 85 KVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEV 144
Query: 93 SEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEK 152
E+E + +EE E+ E+ K A E +E+E E EE + EE G+ + + +
Sbjct: 145 KEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEE----GETEAEAE 200
Query: 153 GEE-DGKEDKNGNEKGEDAKEKE----DGKKGEDGKGNGEDGK----EKG-----EDEKE 198
GEE + KE+K EK E+ KE D K + K K EKG + E
Sbjct: 201 GEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVE 260
Query: 199 EEDRKETGDGKENEDGK---------EKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEA 249
E+ + E GK EKG K ++ + +E ++ E
Sbjct: 261 EKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEV 320
Query: 250 GKEKEDLKEEEEGKEEDEIKEDDGKKEEPQSI 281
GK ++ +EE+E KE + ++ + K+E+P+ +
Sbjct: 321 GKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDV 352
>gi|21735415 centromere protein B [Homo sapiens]
Length = 599
Score = 79.0 bits (193), Expect = 4e-15
Identities = 49/168 (29%), Positives = 90/168 (53%), Gaps = 18/168 (10%)
Query: 112 GGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAK 171
GG + +K+E E+++E+EE++ EE+GE E+++E+GEE+ +E G E GE+ +
Sbjct: 390 GGGPNATITTSLKSEGEEEEEEEEEEEEEEGEG--EEEEEEGEEEEEEGGEGEELGEEEE 447
Query: 172 EKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGK-DVKVKE 230
+E+G + DE+EEED + + +G E ED + + G +
Sbjct: 448 VEEEG--------------DVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQ 493
Query: 231 DEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDDGKKEEP 278
+E + EGG + ++ E+ED EEE+ ++ED+ +++ E P
Sbjct: 494 EEAQCPTLHFLEGGEDSDSDSEEED-DEEEDDEDEDDDDDEEDGDEVP 540
Score = 59.3 bits (142), Expect = 4e-09
Identities = 39/145 (26%), Positives = 71/145 (48%), Gaps = 10/145 (6%)
Query: 85 AKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEA 144
A IT + SE E E +EE E+ +G E++E E + E ++ EE++ EE+G+
Sbjct: 395 ATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDV 454
Query: 145 GKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNG---------EDGKEKGED 195
++++E+ EE E + + E G G G E G++ D
Sbjct: 455 DSDEEEEEDEESSSEGLEAEDWAQGVVE-AGGSFGAYGAQEEAQCPTLHFLEGGEDSDSD 513
Query: 196 EKEEEDRKETGDGKENEDGKEKGDK 220
+EE+D +E + ++++D +E GD+
Sbjct: 514 SEEEDDEEEDDEDEDDDDDEEDGDE 538
Score = 55.1 bits (131), Expect = 7e-08
Identities = 27/65 (41%), Positives = 45/65 (69%), Gaps = 4/65 (6%)
Query: 220 KKEGKDVKVKEDEKEREDGK----EDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDDGKK 275
K EG++ + +E+E+E E+G+ E+EG EEE G E E+L EEEE +EE ++ D+ ++
Sbjct: 402 KSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEE 461
Query: 276 EEPQS 280
E+ +S
Sbjct: 462 EDEES 466
Score = 52.8 bits (125), Expect = 3e-07
Identities = 45/162 (27%), Positives = 72/162 (44%), Gaps = 21/162 (12%)
Query: 56 IDTSAQAVAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEK 115
I TS ++ E ++E EE+ E GE E +EE E+ E+GGE
Sbjct: 397 ITTSLKSEGEEEEEEEEEEEEEE----GEG-------------EEEEEEGEEEEEEGGEG 439
Query: 116 KEAVAAEVKNEEED-QKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKE 174
+E E EE D ++EE+++EE G E +D G + G+ A+E+
Sbjct: 440 EELGEEEEVEEEGDVDSDEEEEEDEESSSEGLEAED---WAQGVVEAGGSFGAYGAQEEA 496
Query: 175 DGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKE 216
+G + + E++ EEED ++ D + EDG E
Sbjct: 497 QCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDE 538
>gi|192807334 arsenate resistance protein 2 isoform d [Homo sapiens]
Length = 872
Score = 79.0 bits (193), Expect = 4e-15
Identities = 50/142 (35%), Positives = 79/142 (55%), Gaps = 9/142 (6%)
Query: 130 QKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDG 189
++E+EE+Q + GE K+++ G G ++ N+K E +KEDGK+ E+ N +D
Sbjct: 269 EQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDE---KKEDGKQAENDSSN-DDK 324
Query: 190 KEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDV----KVKEDEKEREDGK-EDEGG 244
+K E + ++E++KE + + + K++ K G D V E E E E G+ E+E
Sbjct: 325 TKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKE 384
Query: 245 NEEEAGKEKEDLKEEEEGKEED 266
EEA KEKE KEEE K +D
Sbjct: 385 EAEEALKEKEKPKEEEWEKPKD 406
Score = 65.1 bits (157), Expect = 7e-11
Identities = 44/162 (27%), Positives = 78/162 (48%), Gaps = 18/162 (11%)
Query: 120 AAEVKNEEEDQKE----DEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKED 175
AA +K E + + ++E++ E+ G+ G+ K E+G G +G K D EK+
Sbjct: 252 AAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRA-GAGLGDGERKTNDKDEKK- 309
Query: 176 GKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKER 235
EDGK+ E++ +D+ + +G +++ K++ +KE K K + K
Sbjct: 310 -----------EDGKQA-ENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHS 357
Query: 236 EDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDDGKKEE 277
D DEG E + + EEE+ + E+ +KE + KEE
Sbjct: 358 GDDSFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEE 399
Score = 57.0 bits (136), Expect = 2e-08
Identities = 46/159 (28%), Positives = 79/159 (49%), Gaps = 18/159 (11%)
Query: 93 SEKEIVEVKEENIEDATEKGGE--KKE-----AVAAEVKNEEEDQKEDEEDQNEEKGEAG 145
+E ++ +++E E+ K GE KKE A + + + D+ E +ED + + ++
Sbjct: 261 TENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSS 320
Query: 146 KEDKDEKGEEDGKEDKNGNEKGEDA-KEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKE 204
+DK +K E DG ++ EK ED+ KE + K + K +G+D ++G E E E
Sbjct: 321 NDDKTKKSEGDGDKE----EKKEDSEKEAKKSSKKRNRKHSGDDSFDEG-SVSESESESE 375
Query: 205 TGDGKENEDGKEKGDKKEGKDVKVKEDEKEREDGKEDEG 243
+G +E EK + +E K K E+E E K+ G
Sbjct: 376 SGQAEE-----EKEEAEEALKEKEKPKEEEWEKPKDAAG 409
Score = 53.5 bits (127), Expect = 2e-07
Identities = 44/175 (25%), Positives = 74/175 (42%), Gaps = 9/175 (5%)
Query: 60 AQAVAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEV-----KEENIEDATEKGGE 114
A A+ + AV++ E + +I E E++ + KEE A GE
Sbjct: 243 ADAIVKMLDAAVIKM---EGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGE 299
Query: 115 KKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKE 174
+K E K + + + D + ++ K G DK+EK E+ KE K ++K + K
Sbjct: 300 RKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKK-RNRKHSG 358
Query: 175 DGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVK 229
D E E E G+ E+E+E+ +E KE +E K+ ++ K
Sbjct: 359 DDSFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKDAAGLECK 413
Score = 43.5 bits (101), Expect = 2e-04
Identities = 28/98 (28%), Positives = 50/98 (51%), Gaps = 7/98 (7%)
Query: 183 KGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKEREDGKEDE 242
+G E+ E E+EEE + G+ + E+G+ +G+ +DEK +EDGK+ E
Sbjct: 258 EGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEK-KEDGKQAE 316
Query: 243 GGNEEEAGKEKEDLKEEEEGKEEDEIKEDDGKKEEPQS 280
+ + D ++ EG + E K++D +KE +S
Sbjct: 317 NDSSND------DKTKKSEGDGDKEEKKEDSEKEAKKS 348
Score = 31.6 bits (70), Expect = 0.82
Identities = 18/64 (28%), Positives = 33/64 (51%), Gaps = 3/64 (4%)
Query: 220 KKEG---KDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDDGKKE 276
K EG D+++ E E+E E + +++E G+ L + E + + K++DGK+
Sbjct: 256 KMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQA 315
Query: 277 EPQS 280
E S
Sbjct: 316 ENDS 319
>gi|58331218 arsenate resistance protein 2 isoform a [Homo sapiens]
Length = 876
Score = 79.0 bits (193), Expect = 4e-15
Identities = 50/142 (35%), Positives = 79/142 (55%), Gaps = 9/142 (6%)
Query: 130 QKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDG 189
++E+EE+Q + GE K+++ G G ++ N+K E +KEDGK+ E+ N +D
Sbjct: 269 EQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDE---KKEDGKQAENDSSN-DDK 324
Query: 190 KEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDV----KVKEDEKEREDGK-EDEGG 244
+K E + ++E++KE + + + K++ K G D V E E E E G+ E+E
Sbjct: 325 TKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKE 384
Query: 245 NEEEAGKEKEDLKEEEEGKEED 266
EEA KEKE KEEE K +D
Sbjct: 385 EAEEALKEKEKPKEEEWEKPKD 406
Score = 65.1 bits (157), Expect = 7e-11
Identities = 44/162 (27%), Positives = 78/162 (48%), Gaps = 18/162 (11%)
Query: 120 AAEVKNEEEDQKE----DEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKED 175
AA +K E + + ++E++ E+ G+ G+ K E+G G +G K D EK+
Sbjct: 252 AAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRA-GAGLGDGERKTNDKDEKK- 309
Query: 176 GKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKER 235
EDGK+ E++ +D+ + +G +++ K++ +KE K K + K
Sbjct: 310 -----------EDGKQA-ENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHS 357
Query: 236 EDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDDGKKEE 277
D DEG E + + EEE+ + E+ +KE + KEE
Sbjct: 358 GDDSFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEE 399
Score = 57.0 bits (136), Expect = 2e-08
Identities = 46/159 (28%), Positives = 79/159 (49%), Gaps = 18/159 (11%)
Query: 93 SEKEIVEVKEENIEDATEKGGE--KKE-----AVAAEVKNEEEDQKEDEEDQNEEKGEAG 145
+E ++ +++E E+ K GE KKE A + + + D+ E +ED + + ++
Sbjct: 261 TENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSS 320
Query: 146 KEDKDEKGEEDGKEDKNGNEKGEDA-KEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKE 204
+DK +K E DG ++ EK ED+ KE + K + K +G+D ++G E E E
Sbjct: 321 NDDKTKKSEGDGDKE----EKKEDSEKEAKKSSKKRNRKHSGDDSFDEG-SVSESESESE 375
Query: 205 TGDGKENEDGKEKGDKKEGKDVKVKEDEKEREDGKEDEG 243
+G +E EK + +E K K E+E E K+ G
Sbjct: 376 SGQAEE-----EKEEAEEALKEKEKPKEEEWEKPKDAAG 409
Score = 53.5 bits (127), Expect = 2e-07
Identities = 44/175 (25%), Positives = 74/175 (42%), Gaps = 9/175 (5%)
Query: 60 AQAVAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEV-----KEENIEDATEKGGE 114
A A+ + AV++ E + +I E E++ + KEE A GE
Sbjct: 243 ADAIVKMLDAAVIKM---EGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGE 299
Query: 115 KKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKE 174
+K E K + + + D + ++ K G DK+EK E+ KE K ++K + K
Sbjct: 300 RKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKK-RNRKHSG 358
Query: 175 DGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVK 229
D E E E G+ E+E+E+ +E KE +E K+ ++ K
Sbjct: 359 DDSFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKDAAGLECK 413
Score = 43.5 bits (101), Expect = 2e-04
Identities = 28/98 (28%), Positives = 50/98 (51%), Gaps = 7/98 (7%)
Query: 183 KGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKEREDGKEDE 242
+G E+ E E+EEE + G+ + E+G+ +G+ +DEK +EDGK+ E
Sbjct: 258 EGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEK-KEDGKQAE 316
Query: 243 GGNEEEAGKEKEDLKEEEEGKEEDEIKEDDGKKEEPQS 280
+ + D ++ EG + E K++D +KE +S
Sbjct: 317 NDSSND------DKTKKSEGDGDKEEKKEDSEKEAKKS 348
Score = 31.6 bits (70), Expect = 0.82
Identities = 18/64 (28%), Positives = 33/64 (51%), Gaps = 3/64 (4%)
Query: 220 KKEG---KDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDDGKKE 276
K EG D+++ E E+E E + +++E G+ L + E + + K++DGK+
Sbjct: 256 KMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQA 315
Query: 277 EPQS 280
E S
Sbjct: 316 ENDS 319
>gi|157738619 smoothelin-like 1 [Homo sapiens]
Length = 512
Score = 77.0 bits (188), Expect = 2e-14
Identities = 88/290 (30%), Positives = 128/290 (44%), Gaps = 32/290 (11%)
Query: 6 AAGQGDMRQEPKRRSARLSAMLVPVTPEVKPKRTSSSRKMKTKSDMMEENIDTSAQAVAE 65
A G+ D E + + + L V P + + +M EE T+ +A+ E
Sbjct: 5 AVGESDCSAEAREKMEQKEGKLSEDGTTVSP--AADNPEMSGGGAPAEETKGTAGKAINE 62
Query: 66 TKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKN 125
E E A + E + EVK +E E GG KE AE+K
Sbjct: 63 GPP---TESGKQEKAPAEDGMSAELQGEANGLDEVK---VESQREAGG--KEDAEAELKK 114
Query: 126 EEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGN 185
E+ +++E E G +E K E E + KE +EK + A+EKE K E G+
Sbjct: 115 EDGEKEETTVGSQEMTGRK-EETKSEPKEAEEKESTLASEK-QKAEEKE--AKPESGQKA 170
Query: 186 GEDGKEKGEDEK--EEEDRK-----ETGDGKE-NEDGKEKGDKKEGK---DVKVKEDEKE 234
+ ++K E + EEED K ETG KE + + KEK +E K V EDE +
Sbjct: 171 DANDRDKPEPKATVEEEDAKTASQEETGQRKECSTEPKEKATDEEAKAESQKAVVEDEAK 230
Query: 235 RE----DGKED--EGGNEE-EAGKEKEDLKEEEEGKEEDEIKEDDGKKEE 277
E DGKE+ G EE +A +E ED +E E G +E ++D K+ E
Sbjct: 231 AEPKEPDGKEEAKHGAKEEADAKEEAEDAEEAEPGSPSEEQEQDVEKEPE 280
Score = 69.3 bits (168), Expect = 4e-12
Identities = 62/235 (26%), Positives = 100/235 (42%), Gaps = 25/235 (10%)
Query: 36 PKRTSSSRKMKTKSDMMEENIDTSAQAVAETK----QEAVVEEDYNENAKNGEAKITEAP 91
P S ++ D M + A + E K +EA +ED K + + E
Sbjct: 64 PPTESGKQEKAPAEDGMSAELQGEANGLDEVKVESQREAGGKEDAEAELKKEDGEKEETT 123
Query: 92 ASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGK-EDKD 150
+E+ KEE + E EK+ +A+E + EE + + E Q + + K E K
Sbjct: 124 VGSQEMTGRKEETKSEPKE-AEEKESTLASEKQKAEEKEAKPESGQKADANDRDKPEPKA 182
Query: 151 EKGEEDGK---EDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGD 207
EED K +++ G K + KE K D + E K EDE + E ++ G
Sbjct: 183 TVEEEDAKTASQEETGQRKECSTEPKE---KATDEEAKAESQKAVVEDEAKAEPKEPDGK 239
Query: 208 GKENEDGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEG 262
+ KE+ D KE E ED +E E G+ E ++++D+++E EG
Sbjct: 240 EEAKHGAKEEADAKE-----------EAEDAEEAEPGSPSE--EQEQDVEKEPEG 281
Score = 62.8 bits (151), Expect = 3e-10
Identities = 63/280 (22%), Positives = 114/280 (40%), Gaps = 14/280 (5%)
Query: 3 KRKAAGQGDMRQEPKRRSARLSAMLVPVTPEVKPKRTSSSRKMKTKSDMMEENIDTSAQA 62
+ KA + M E + + L + V E K + + K D +E +Q
Sbjct: 71 QEKAPAEDGMSAELQGEANGLDEVKVESQREAGGKEDAEAELKK--EDGEKEETTVGSQE 128
Query: 63 VAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAE 122
+ K+E E + A+ E+ + ASEK+ E KE E + ++ +
Sbjct: 129 MTGRKEETKSEP---KEAEEKESTL----ASEKQKAEEKEAKPESGQKADANDRDKPEPK 181
Query: 123 VKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDG 182
EEED K +++ ++ E E K++ +E+ K + ++AK + K DG
Sbjct: 182 ATVEEEDAKTASQEETGQRKECSTEPKEKATDEEAKAESQKAVVEDEAKAE---PKEPDG 238
Query: 183 KGNGEDGKEKGEDEKEE-EDRKETGDGKENEDGKEKGDKK-EGKDVKVKEDEKEREDGKE 240
K + G ++ D KEE ED +E G +E+ ++ +K+ EG + +E +
Sbjct: 239 KEEAKHGAKEEADAKEEAEDAEEAEPGSPSEEQEQDVEKEPEGGAGVIPSSPEEWPESPT 298
Query: 241 DEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDDGKKEEPQS 280
EG N G + + + E D + P+S
Sbjct: 299 GEGHNLSTDGLGPDCVASGQTSPSASESSPSDVPQSPPES 338
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 76.6 bits (187), Expect = 2e-14
Identities = 60/242 (24%), Positives = 123/242 (50%), Gaps = 24/242 (9%)
Query: 35 KPKRTSSSRKMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKITEAPASE 94
K +R +KM + + M E T Q QE + E+ E + E K+ E E
Sbjct: 519 KEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREE--ERMREREKKMRE----E 572
Query: 95 KEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGE 154
+E++ +EE +++ EK E++E + E + + ++Q+E +Q E+ E +EDK ++ E
Sbjct: 573 EEMMREQEEKMQEQEEKMREQEEKMW-EQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQE 631
Query: 155 ED-GKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENED 213
E ++++ E+ E E+E+ + ++ K ++ K +G++EK
Sbjct: 632 EMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKM--------------- 676
Query: 214 GKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDDG 273
+E+ +K +G++ K++E E++ +E G EE+ ++E + +EE +E++E D
Sbjct: 677 -REQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQK 735
Query: 274 KK 275
+K
Sbjct: 736 EK 737
Score = 68.6 bits (166), Expect = 6e-12
Identities = 49/249 (19%), Positives = 126/249 (50%), Gaps = 4/249 (1%)
Query: 32 PEVKPKRTSSSRKMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKITEAP 91
PE K K + + + + E+ Q +++ + ++ ++ + E
Sbjct: 436 PEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKM 495
Query: 92 ASEKEIVEVKEENIEDATEKGGEKKEAVAAEVK--NEEEDQKEDEEDQNEEKGEAGKEDK 149
+++ + +EE + + E+ EK+E + + K +EE +E+++ Q +EK +E+K
Sbjct: 496 RDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEK 555
Query: 150 DEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGK 209
+ E + +K E+ E +E+E+ + ++ K ++ K ++EK +E ++ + +
Sbjct: 556 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 615
Query: 210 ENEDGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGK--EEDE 267
E +E+ DK + ++ + E E++ ++ +E EE+ +++E ++E+EE +E++
Sbjct: 616 EKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEK 675
Query: 268 IKEDDGKKE 276
++E + K +
Sbjct: 676 MREQEEKMQ 684
Score = 66.2 bits (160), Expect = 3e-11
Identities = 72/298 (24%), Positives = 136/298 (45%), Gaps = 46/298 (15%)
Query: 13 RQEPKRRSARLSAMLVPVTPEVKPKRTSSSRKMKTKSDMME-ENIDTSAQAVAETKQEAV 71
++E + R+ + E + R + K + +M E E + Q + E K++
Sbjct: 384 QEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLW 443
Query: 72 VEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQK 131
+E E E KI E +EE I D E G++K+ E E+EDQ
Sbjct: 444 EQEKMQEQ----EEKIWE-----------QEEKIRDQEEMWGQEKKMWRQEKMREQEDQM 488
Query: 132 EDEE-----------DQNEEKGEAGKE--DKDEKGEEDGK----EDKNGNEKGEDAKEK- 173
++E DQ E E + +K+E+ E K E+K EK +EK
Sbjct: 489 WEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKK 548
Query: 174 ---EDGKKGEDGKGNGEDGKEKGEDE--KEEEDRKETGDGKENEDGK---EKGDKKEGKD 225
++ K E+ + + K + E+E +E+E++ + + K E + E+ +K + ++
Sbjct: 549 TWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQE 608
Query: 226 VKV-KEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGK---EEDEIKEDDGKKEEPQ 279
K+ +++EK E +ED+ +EE E+E+ +E+E K +E++++E + K E +
Sbjct: 609 EKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQE 666
Score = 64.3 bits (155), Expect = 1e-10
Identities = 59/262 (22%), Positives = 131/262 (50%), Gaps = 17/262 (6%)
Query: 33 EVKPKRTSSSRKMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKITEAPA 92
E + K +M + + + E + + +QE ++E+ E + E K+ E
Sbjct: 349 EQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEE--ERIREREKKMREEEE 406
Query: 93 S---EKEIVEVKEENIEDATEKG------GEKKEAVAAEVKNEEEDQK--EDEEDQNEEK 141
+ ++E ++ +EEN+ + EK E+KE + + K +E+++K E EE +++
Sbjct: 407 TMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQE 466
Query: 142 GEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEED 201
G+E K + E+ +++ E+ E +++E ++ + +D + + ++E+ E
Sbjct: 467 EMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQ 526
Query: 202 RKE-TGDGKENEDGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEE 260
+K + K E+ K + +K+ D + K E+ER +E + EEE +E+E+ +E+
Sbjct: 527 KKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQ 586
Query: 261 EGK---EEDEIKEDDGKKEEPQ 279
E K +E+++ E + K +E +
Sbjct: 587 EEKMREQEEKMWEQEEKMQEQE 608
Score = 61.2 bits (147), Expect = 1e-09
Identities = 54/250 (21%), Positives = 127/250 (50%), Gaps = 16/250 (6%)
Query: 33 EVKPKRTSSSRKMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKI---TE 89
E + K K++ + +M + Q +++ + E++ E ++ E K+ E
Sbjct: 450 EQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQE--EKMRDQEQKMWDQEE 507
Query: 90 APASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQK-EDEEDQNEEKGEAGKED 148
+ E + KEE + + +K +++E + E K +E+++K D+E++ E+ + +
Sbjct: 508 RMWEQDERLREKEERMREQ-KKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMRERE 566
Query: 149 KDEKGEED--GKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEK----EEEDR 202
K + EE+ ++++ E+ E +E+E+ ++ K ++ K ++EK EEED+
Sbjct: 567 KKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDK 626
Query: 203 KETGD---GKENEDGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEE 259
+ + ++ E +E+ +K ++ K++E E++ + +E G EE+ +++E ++ +
Sbjct: 627 MQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQ 686
Query: 260 EEGKEEDEIK 269
EE E E K
Sbjct: 687 EEKMREQEEK 696
Score = 58.5 bits (140), Expect = 6e-09
Identities = 54/228 (23%), Positives = 111/228 (48%), Gaps = 13/228 (5%)
Query: 67 KQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEE-----NIEDATEKGGEKKEAVAA 121
+++A+ E Y N E K A EK + E+ N+++ K K +
Sbjct: 167 ERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQ 226
Query: 122 EVKN--EEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKG 179
N +EE +++EE + +EK +E+K + EE +E + + E+ +++ +
Sbjct: 227 VQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLR 286
Query: 180 EDGKGNGEDGKEKGEDEK--EEEDRKETGDGK---ENEDGKEKGDKKEGKDVKVKEDEKE 234
E K E KE E +K E+E++ + + K + E +E+ +K ++ ++ E EK+
Sbjct: 287 EQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQ 346
Query: 235 REDGKEDEGGNEEEAGKEKEDLKEEEEG-KEEDEIKEDDGKKEEPQSI 281
+ ++ EE ++ E L+E+EE +E++++ E + K +E + I
Sbjct: 347 MREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERI 394
Score = 57.0 bits (136), Expect = 2e-08
Identities = 59/267 (22%), Positives = 131/267 (49%), Gaps = 21/267 (7%)
Query: 33 EVKPKRTSSSRKMKTKSDMM---EENIDTSAQAVAETKQEAVVEED----YNENAKNGEA 85
E + K KM+ + + M EE + + + E +Q+ +E+ +E + E
Sbjct: 314 EQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEE 373
Query: 86 KITEAPAS-EKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEA 144
++ E E+E +EE I + +K E++E + + EE+ QK++E +E+ E
Sbjct: 374 RMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQ---EEKMQKQEENMWEQEEKEW 430
Query: 145 GKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKE 204
++ E+ E+ +++K E+ E E+E+ + ++ E + E +E+ED+
Sbjct: 431 QQQRLPEQKEKLWEQEKM-QEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMW 489
Query: 205 TGDGKENEDGKEKGDKKEG---KDVKVKEDEKEREDGK----EDEGGNEEEAGKEKEDLK 257
+ K + ++ D++E +D +++E E+ + K ++E EE+ +E+E
Sbjct: 490 EQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKT 549
Query: 258 --EEEEGKEEDEIKEDDGKKEEPQSIV 282
+EE+ +EE+ ++E + K E + ++
Sbjct: 550 WDQEEKMREEERMREREKKMREEEEMM 576
Score = 55.5 bits (132), Expect = 5e-08
Identities = 45/211 (21%), Positives = 102/211 (48%), Gaps = 14/211 (6%)
Query: 12 MRQEPKRRSARLSAMLVPVTPEVKPKRTSSSRKMKTKSDMMEENIDTSAQAVAETKQEAV 71
MR+E K + + + +KM+ + +MM E + + + +++
Sbjct: 536 MREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEE 595
Query: 72 VEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQK 131
+ E + E K+ E EK + +E+ +++ E E++E +++ +EE
Sbjct: 596 KMWEQEEKMQEQEEKMWEQ--EEKMWEQEEEDKMQEQEEMMWEQEE----KMQEQEEKMW 649
Query: 132 EDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAK--EKEDGKKGEDGKGNGEDG 189
E EE E++ + ++++ +G+E+ ++ +G++ K E+E+ +G++ K G++
Sbjct: 650 EQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEE 709
Query: 190 KEKGEDEK---EEEDRKETGDGKENEDGKEK 217
K G++EK +EE R++ + D KEK
Sbjct: 710 KMWGQEEKMWGQEEMREKE---ERIRDQKEK 737
Score = 54.7 bits (130), Expect = 9e-08
Identities = 52/261 (19%), Positives = 131/261 (50%), Gaps = 15/261 (5%)
Query: 13 RQEPK--RRSARLSAMLVPVTPEVKPKRTSSSRKMKTKSDMMEENIDTSAQAVAETKQEA 70
+QE K R+ RL + + + R R + + ++ E+ + Q ++E
Sbjct: 252 KQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQ 311
Query: 71 VVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQ 130
+ E++ E E K+ E ++E + +EE + + ++ E+++ +++++EE
Sbjct: 312 MQEQE--EKMWEQEEKMRE----QEEKMWRQEERLWEQEKQMREQEQ----KMRDQEERM 361
Query: 131 KEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGK 190
E +E E++ +++K + EE +E++ E+ + +E+E+ + ++ K ++ +
Sbjct: 362 WEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQE-E 420
Query: 191 EKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKERED--GKEDEGGNEEE 248
E E++E ++ + KE +EK ++E K + +E +++E+ G+E + +E+
Sbjct: 421 NMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEK 480
Query: 249 AGKEKEDLKEEEEGKEEDEIK 269
++++ + E+EE + E K
Sbjct: 481 MREQEDQMWEQEEKMRDQEQK 501
Score = 53.5 bits (127), Expect = 2e-07
Identities = 51/239 (21%), Positives = 113/239 (47%), Gaps = 6/239 (2%)
Query: 43 RKMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKE 102
R+ + K EE + + + E ++E +E K + + E+++ E +E
Sbjct: 265 REQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWE-QE 323
Query: 103 ENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGK--EDKDEKGEEDGKED 160
E + + EK ++E + + K E Q++ DQ E E + +K+E+ E K
Sbjct: 324 EKMREQEEKMWRQEERLWEQEKQMRE-QEQKMRDQEERMWEQDERLREKEERMREQEKMW 382
Query: 161 KNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDK 220
+ + E+ + +E KK + + + +EK +K+EE+ E + + + + +
Sbjct: 383 EQEEKMQEEERIREREKKMREEEETMREQEEK--MQKQEENMWEQEEKEWQQQRLPEQKE 440
Query: 221 KEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDDGKKEEPQ 279
K + K++E E++ + +E EE G+EK+ ++E+ ++ED++ E + K + +
Sbjct: 441 KLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQE 499
Score = 53.1 bits (126), Expect = 3e-07
Identities = 52/244 (21%), Positives = 122/244 (50%), Gaps = 14/244 (5%)
Query: 43 RKMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKE 102
RK + K EE + + E ++E + ++ + E + E E++ + +E
Sbjct: 251 RKQEEKMWRQEERLREQEGKMRE-QEEKMRRQEKRLREQEKELREQEKELREQKKLREQE 309
Query: 103 ENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDG--KED 160
E +++ EK E++E +++ +EE EE E++ + ++++ + +E+ ++D
Sbjct: 310 EQMQEQEEKMWEQEE----KMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQD 365
Query: 161 KNGNEKGEDAKEKEDGKKGEDGKGNGE---DGKEKGEDEKEEEDRKETGDGKENEDGKEK 217
+ EK E +E+E + E+ E + ++K +E+E +E K+ E+ E+
Sbjct: 366 ERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQ 425
Query: 218 GDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEE--GKEEDEIKEDDGKK 275
+K+ + ++ EK E K E EE+ +++E ++++EE G+E+ +++ ++
Sbjct: 426 EEKEWQQQRLPEQKEKLWEQEKMQE--QEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMRE 483
Query: 276 EEPQ 279
+E Q
Sbjct: 484 QEDQ 487
Score = 52.4 bits (124), Expect = 4e-07
Identities = 48/244 (19%), Positives = 121/244 (49%), Gaps = 16/244 (6%)
Query: 37 KRTSSSRKMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKITEAPASEKE 96
+ T ++ ++K K+ ++E + +AE+++ + N K + K+ A
Sbjct: 177 RNTITNEELKKKNAELQEKL-----RLAESEKSEI-----QLNVKELKRKLERAKFL--- 223
Query: 97 IVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEED 156
+ +V+ +++ + E+ +++ +EE EE E++G+ +E +++ ++
Sbjct: 224 LPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKM-REQEEKMRRQE 282
Query: 157 GKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKE 216
+ + E E KE + KK + + ++ +EK +++E+ +E ++ E E
Sbjct: 283 KRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWE 342
Query: 217 KGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEG-KEEDEIKEDDGKK 275
+ + ++ K++ D++ER +++ +EE +E+E + E+EE +EE+ I+E + K
Sbjct: 343 QEKQMREQEQKMR-DQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKM 401
Query: 276 EEPQ 279
E +
Sbjct: 402 REEE 405
Score = 52.0 bits (123), Expect = 6e-07
Identities = 61/289 (21%), Positives = 137/289 (47%), Gaps = 37/289 (12%)
Query: 14 QEPKRRSARLSAMLVPVTPEVKPKRTSSSRKMKTKSDMMEENIDTSAQAVAETKQEAVVE 73
+E K+++A L L E K + + +++K K +E Q T QE +
Sbjct: 183 EELKKKNAELQEKLRLAESE-KSEIQLNVKELKRK---LERAKFLLPQVQTNTLQEEMWR 238
Query: 74 EDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKED 133
++ E + E KI + ++E + +EE + + K E++E + + K E +KE
Sbjct: 239 QE--EELREQEKKIRK----QEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKEL 292
Query: 134 EEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEK-----------EDGKKGEDG 182
E + E + + +++E+ +E ++ EK + +EK E + ++
Sbjct: 293 REQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQ 352
Query: 183 KGNGEDGKEKGEDE--KEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKEREDGKE 240
K ++ + +DE +E+E+R +E E E+ +K + ++ +++E EK+ + +E
Sbjct: 353 KMRDQEERMWEQDERLREKEERM-----REQEKMWEQEEKMQ-EEERIREREKKMREEEE 406
Query: 241 DEGGNEEEAGKEKEDLKEEEE--------GKEEDEIKEDDGKKEEPQSI 281
EE+ K++E++ E+EE ++++++ E + +E+ + I
Sbjct: 407 TMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKI 455
Score = 50.1 bits (118), Expect = 2e-06
Identities = 56/266 (21%), Positives = 125/266 (46%), Gaps = 17/266 (6%)
Query: 14 QEPKRRSARLSAMLVPVTPEVKPKRTSSSRKMKTKSDMMEENIDTSAQAVAETKQEAVVE 73
+E KR+ R +L P+V+ T + + ++ E+ Q +QE +
Sbjct: 211 KELKRKLERAKFLL----PQVQTN-TLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLR 265
Query: 74 EDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKED 133
E + + E + EK + E ++E E E +KK E E+E++ +
Sbjct: 266 EQEGKMREQEE----KMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWE 321
Query: 134 EEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEK---EDGKKGEDGKGNGEDGK 190
+E++ E+ E ++ E++ K+ + +K D +E+ +D + E + E K
Sbjct: 322 QEEKMREQEEKMWRQEERLWEQE-KQMREQEQKMRDQEERMWEQDERLREKEERMREQEK 380
Query: 191 EKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKED--EKEREDGKEDEGGNEEE 248
++EK +E+ + K+ + +E ++E K K +E+ E+E ++ ++ ++E
Sbjct: 381 MWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKE 440
Query: 249 AGKEKEDLKEEEE--GKEEDEIKEDD 272
E+E ++E+EE ++E++I++ +
Sbjct: 441 KLWEQEKMQEQEEKIWEQEEKIRDQE 466
>gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens]
Length = 755
Score = 76.3 bits (186), Expect = 3e-14
Identities = 69/207 (33%), Positives = 110/207 (53%), Gaps = 31/207 (14%)
Query: 99 EVKEENIEDATEKGGEKKEAVAAEVKNEEED---QKEDEEDQNEEKGEAGKEDKDEKGEE 155
E K++ +++ E+ G KE+ K EE+ KE EED +E++ + ED EK E
Sbjct: 502 ESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKESEEDDSEKESD---EDCSEKQSE 558
Query: 156 DGKE---DKNGNEK--GEDAKEKE------DGKKGEDGKGNGE---DGKEKGEDEK--EE 199
DG E ++NG EK E+ EKE D + E+ N E DG EK DE+ E
Sbjct: 559 DGSEREFEENGLEKDLDEEGSEKELHENVLDKELEENDSENSEFEDDGSEKVLDEEGSER 618
Query: 200 EDRKETGDGKENEDGKEK--GDKKEGKDVKVKEDEK--EREDGKEDEGGNEEEAGKEKED 255
E +++ + +E ED EK D+ + K+ + DEK E D K +EG +E+ +E +D
Sbjct: 619 EFDEDSDEKEEEEDTYEKVFDDESDEKEDEEYADEKGLEAADKKAEEGDADEKLFEESDD 678
Query: 256 LKEEE-EGKE----EDEIKEDDGKKEE 277
++E+ +GKE ++++ EDD E+
Sbjct: 679 KEDEDADGKEVEDADEKLFEDDDSNEK 705
Score = 75.5 bits (184), Expect = 5e-14
Identities = 61/210 (29%), Positives = 93/210 (44%), Gaps = 13/210 (6%)
Query: 75 DYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDE 134
++ +K + A E+ I E K E ED GGE +E + E +KE E
Sbjct: 404 EHPSTSKMNAQETATGMAFEEPIDEKKFEKTED----GGEFEEGASENNAKESSPEKEAE 459
Query: 135 EDQNEEKGEAGKEDKDEKGEEDGKEDKNGNE---KGEDAKEKEDGKKGEDGKGNGEDGKE 191
E E++ E G + +G KE + GN ED+ +KE KK +
Sbjct: 460 EGCPEKESEEGCPKRGFEGSCSQKESEEGNPVRGSEEDSPKKESKKKTLKNDCEENGLAK 519
Query: 192 KGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKERE---DGKE---DEGGN 245
+ ED+ +E +E G KE+E+ + + E K ED ERE +G E DE G+
Sbjct: 520 ESEDDLNKESEEEVGPTKESEEDDSEKESDEDCSEKQSEDGSEREFEENGLEKDLDEEGS 579
Query: 246 EEEAGKEKEDLKEEEEGKEEDEIKEDDGKK 275
E+E + D + EE E E ++D +K
Sbjct: 580 EKELHENVLDKELEENDSENSEFEDDGSEK 609
Score = 73.2 bits (178), Expect = 2e-13
Identities = 76/268 (28%), Positives = 120/268 (44%), Gaps = 34/268 (12%)
Query: 39 TSSSRKMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNENA--KNGEAKITEAPASEKE 96
++S R +++ E+ TS ET EE +E K + E ASE
Sbjct: 389 SASERAGPSRARHFSEHPSTSKMNAQETATGMAFEEPIDEKKFEKTEDGGEFEEGASENN 448
Query: 97 IVEVKEENIEDATEKGGEKKEAVAAEVKNEEE---DQKEDEEDQNEEKGEAGKEDKDEKG 153
KE + E E+G +KE+ K E QKE EE G E+ K
Sbjct: 449 ---AKESSPEKEAEEGCPEKESEEGCPKRGFEGSCSQKESEEGNPVR----GSEEDSPKK 501
Query: 154 EEDGKEDKNGNEKGEDAKEKED--GKKGEDGKGNGEDGKEKGEDEKEEED--RKETGDGK 209
E K KN E+ AKE ED K+ E+ G ++ +E +++ +ED K++ DG
Sbjct: 502 ESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKESEEDDSEKESDEDCSEKQSEDGS 561
Query: 210 ENE---DGKEKGDKKEGKDVKVKE-------DEKEREDGKEDEGGNE---EEAGKEKE-- 254
E E +G EK +EG + ++ E +E + E+ + ++ G+E +E G E+E
Sbjct: 562 EREFEENGLEKDLDEEGSEKELHENVLDKELEENDSENSEFEDDGSEKVLDEEGSEREFD 621
Query: 255 ---DLKEEEEGKEEDEIKEDDGKKEEPQ 279
D KEEEE E ++ +KE+ +
Sbjct: 622 EDSDEKEEEEDTYEKVFDDESDEKEDEE 649
Score = 72.0 bits (175), Expect = 5e-13
Identities = 61/206 (29%), Positives = 106/206 (51%), Gaps = 18/206 (8%)
Query: 47 TKSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVE-VKEENI 105
TK +++ S + +E + E E ++ EN G K + SEKE+ E V ++ +
Sbjct: 536 TKESEEDDSEKESDEDCSEKQSEDGSEREFEEN---GLEKDLDEEGSEKELHENVLDKEL 592
Query: 106 EDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKN-GN 164
E+ + E ++ + +V +EE ++E +ED +E++ E +K E D KED+ +
Sbjct: 593 EENDSENSEFEDDGSEKVLDEEGSEREFDEDSDEKEEEEDTYEKVFDDESDEKEDEEYAD 652
Query: 165 EKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGK 224
EKG +A +K K E+G + + +E D+KE+ED DGKE ED EK + +
Sbjct: 653 EKGLEAADK----KAEEGDADEKLFEES--DDKEDED----ADGKEVEDADEKLFEDDDS 702
Query: 225 DVKVKEDEKEREDGKEDEGGNEEEAG 250
+ K+ ++E ED E + +E G
Sbjct: 703 NEKLFDEE---EDSSEKLFDDSDERG 725
Score = 62.8 bits (151), Expect = 3e-10
Identities = 56/195 (28%), Positives = 95/195 (48%), Gaps = 21/195 (10%)
Query: 37 KRTSSSRKMKTKSDMMEENIDT--SAQAVAETKQEAVVEEDYNENAK---NGEAKITEAP 91
K++ + + + + +E+++D S + + E + +EE+ +EN++ +G K+ +
Sbjct: 555 KQSEDGSEREFEENGLEKDLDEEGSEKELHENVLDKELEENDSENSEFEDDGSEKVLDEE 614
Query: 92 ASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDE 151
SE+E E D+ EK E++E +V ++E D+KEDEE +EK G E D+
Sbjct: 615 GSEREFDE-------DSDEK--EEEEDTYEKVFDDESDEKEDEE-YADEK---GLEAADK 661
Query: 152 KGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKG---NGEDGKEKGEDEKEEEDRKETGDG 208
K EE ++K E + E DGK+ ED +D EK DE+E+ K D
Sbjct: 662 KAEEGDADEKLFEESDDKEDEDADGKEVEDADEKLFEDDDSNEKLFDEEEDSSEKLFDDS 721
Query: 209 KENEDGKEKGDKKEG 223
E G +EG
Sbjct: 722 DERGTLGGFGSVEEG 736
Score = 43.5 bits (101), Expect = 2e-04
Identities = 46/184 (25%), Positives = 72/184 (39%), Gaps = 12/184 (6%)
Query: 105 IEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGN 164
+E+ + + E+ A + E ++ D AG E N
Sbjct: 355 VEETSREREERLRGWEAFLNAPEANRGLRRSDSVSASERAGPSRARHFSEHPSTSKMNAQ 414
Query: 165 EK--GEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKE 222
E G +E D KK E + GE E+ E + KE+ KE E+G + + +E
Sbjct: 415 ETATGMAFEEPIDEKKFEKTEDGGEF-----EEGASENNAKESSPEKEAEEGCPEKESEE 469
Query: 223 GKDVKVKE---DEKEREDGKEDEGGNEEEAGKE--KEDLKEEEEGKEEDEIKEDDGKKEE 277
G + E +KE E+G G E+ KE K+ LK + E + EDD KE
Sbjct: 470 GCPKRGFEGSCSQKESEEGNPVRGSEEDSPKKESKKKTLKNDCEENGLAKESEDDLNKES 529
Query: 278 PQSI 281
+ +
Sbjct: 530 EEEV 533
>gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens]
Length = 755
Score = 76.3 bits (186), Expect = 3e-14
Identities = 69/207 (33%), Positives = 110/207 (53%), Gaps = 31/207 (14%)
Query: 99 EVKEENIEDATEKGGEKKEAVAAEVKNEEED---QKEDEEDQNEEKGEAGKEDKDEKGEE 155
E K++ +++ E+ G KE+ K EE+ KE EED +E++ + ED EK E
Sbjct: 502 ESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKESEEDDSEKESD---EDCSEKQSE 558
Query: 156 DGKE---DKNGNEK--GEDAKEKE------DGKKGEDGKGNGE---DGKEKGEDEK--EE 199
DG E ++NG EK E+ EKE D + E+ N E DG EK DE+ E
Sbjct: 559 DGSEREFEENGLEKDLDEEGSEKELHENVLDKELEENDSENSEFEDDGSEKVLDEEGSER 618
Query: 200 EDRKETGDGKENEDGKEK--GDKKEGKDVKVKEDEK--EREDGKEDEGGNEEEAGKEKED 255
E +++ + +E ED EK D+ + K+ + DEK E D K +EG +E+ +E +D
Sbjct: 619 EFDEDSDEKEEEEDTYEKVFDDESDEKEDEEYADEKGLEAADKKAEEGDADEKLFEESDD 678
Query: 256 LKEEE-EGKE----EDEIKEDDGKKEE 277
++E+ +GKE ++++ EDD E+
Sbjct: 679 KEDEDADGKEVEDADEKLFEDDDSNEK 705
Score = 75.5 bits (184), Expect = 5e-14
Identities = 61/210 (29%), Positives = 93/210 (44%), Gaps = 13/210 (6%)
Query: 75 DYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDE 134
++ +K + A E+ I E K E ED GGE +E + E +KE E
Sbjct: 404 EHPSTSKMNAQETATGMAFEEPIDEKKFEKTED----GGEFEEGASENNAKESSPEKEAE 459
Query: 135 EDQNEEKGEAGKEDKDEKGEEDGKEDKNGNE---KGEDAKEKEDGKKGEDGKGNGEDGKE 191
E E++ E G + +G KE + GN ED+ +KE KK +
Sbjct: 460 EGCPEKESEEGCPKRGFEGSCSQKESEEGNPVRGSEEDSPKKESKKKTLKNDCEENGLAK 519
Query: 192 KGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKERE---DGKE---DEGGN 245
+ ED+ +E +E G KE+E+ + + E K ED ERE +G E DE G+
Sbjct: 520 ESEDDLNKESEEEVGPTKESEEDDSEKESDEDCSEKQSEDGSEREFEENGLEKDLDEEGS 579
Query: 246 EEEAGKEKEDLKEEEEGKEEDEIKEDDGKK 275
E+E + D + EE E E ++D +K
Sbjct: 580 EKELHENVLDKELEENDSENSEFEDDGSEK 609
Score = 73.2 bits (178), Expect = 2e-13
Identities = 76/268 (28%), Positives = 120/268 (44%), Gaps = 34/268 (12%)
Query: 39 TSSSRKMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNENA--KNGEAKITEAPASEKE 96
++S R +++ E+ TS ET EE +E K + E ASE
Sbjct: 389 SASERAGPSRARHFSEHPSTSKMNAQETATGMAFEEPIDEKKFEKTEDGGEFEEGASENN 448
Query: 97 IVEVKEENIEDATEKGGEKKEAVAAEVKNEEE---DQKEDEEDQNEEKGEAGKEDKDEKG 153
KE + E E+G +KE+ K E QKE EE G E+ K
Sbjct: 449 ---AKESSPEKEAEEGCPEKESEEGCPKRGFEGSCSQKESEEGNPVR----GSEEDSPKK 501
Query: 154 EEDGKEDKNGNEKGEDAKEKED--GKKGEDGKGNGEDGKEKGEDEKEEED--RKETGDGK 209
E K KN E+ AKE ED K+ E+ G ++ +E +++ +ED K++ DG
Sbjct: 502 ESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKESEEDDSEKESDEDCSEKQSEDGS 561
Query: 210 ENE---DGKEKGDKKEGKDVKVKE-------DEKEREDGKEDEGGNE---EEAGKEKE-- 254
E E +G EK +EG + ++ E +E + E+ + ++ G+E +E G E+E
Sbjct: 562 EREFEENGLEKDLDEEGSEKELHENVLDKELEENDSENSEFEDDGSEKVLDEEGSEREFD 621
Query: 255 ---DLKEEEEGKEEDEIKEDDGKKEEPQ 279
D KEEEE E ++ +KE+ +
Sbjct: 622 EDSDEKEEEEDTYEKVFDDESDEKEDEE 649
Score = 72.0 bits (175), Expect = 5e-13
Identities = 61/206 (29%), Positives = 106/206 (51%), Gaps = 18/206 (8%)
Query: 47 TKSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVE-VKEENI 105
TK +++ S + +E + E E ++ EN G K + SEKE+ E V ++ +
Sbjct: 536 TKESEEDDSEKESDEDCSEKQSEDGSEREFEEN---GLEKDLDEEGSEKELHENVLDKEL 592
Query: 106 EDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKN-GN 164
E+ + E ++ + +V +EE ++E +ED +E++ E +K E D KED+ +
Sbjct: 593 EENDSENSEFEDDGSEKVLDEEGSEREFDEDSDEKEEEEDTYEKVFDDESDEKEDEEYAD 652
Query: 165 EKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGK 224
EKG +A +K K E+G + + +E D+KE+ED DGKE ED EK + +
Sbjct: 653 EKGLEAADK----KAEEGDADEKLFEES--DDKEDED----ADGKEVEDADEKLFEDDDS 702
Query: 225 DVKVKEDEKEREDGKEDEGGNEEEAG 250
+ K+ ++E ED E + +E G
Sbjct: 703 NEKLFDEE---EDSSEKLFDDSDERG 725
Score = 62.8 bits (151), Expect = 3e-10
Identities = 56/195 (28%), Positives = 95/195 (48%), Gaps = 21/195 (10%)
Query: 37 KRTSSSRKMKTKSDMMEENIDT--SAQAVAETKQEAVVEEDYNENAK---NGEAKITEAP 91
K++ + + + + +E+++D S + + E + +EE+ +EN++ +G K+ +
Sbjct: 555 KQSEDGSEREFEENGLEKDLDEEGSEKELHENVLDKELEENDSENSEFEDDGSEKVLDEE 614
Query: 92 ASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDE 151
SE+E E D+ EK E++E +V ++E D+KEDEE +EK G E D+
Sbjct: 615 GSEREFDE-------DSDEK--EEEEDTYEKVFDDESDEKEDEE-YADEK---GLEAADK 661
Query: 152 KGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKG---NGEDGKEKGEDEKEEEDRKETGDG 208
K EE ++K E + E DGK+ ED +D EK DE+E+ K D
Sbjct: 662 KAEEGDADEKLFEESDDKEDEDADGKEVEDADEKLFEDDDSNEKLFDEEEDSSEKLFDDS 721
Query: 209 KENEDGKEKGDKKEG 223
E G +EG
Sbjct: 722 DERGTLGGFGSVEEG 736
Score = 43.5 bits (101), Expect = 2e-04
Identities = 46/184 (25%), Positives = 72/184 (39%), Gaps = 12/184 (6%)
Query: 105 IEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGN 164
+E+ + + E+ A + E ++ D AG E N
Sbjct: 355 VEETSREREERLRGWEAFLNAPEANRGLRRSDSVSASERAGPSRARHFSEHPSTSKMNAQ 414
Query: 165 EK--GEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKE 222
E G +E D KK E + GE E+ E + KE+ KE E+G + + +E
Sbjct: 415 ETATGMAFEEPIDEKKFEKTEDGGEF-----EEGASENNAKESSPEKEAEEGCPEKESEE 469
Query: 223 GKDVKVKE---DEKEREDGKEDEGGNEEEAGKE--KEDLKEEEEGKEEDEIKEDDGKKEE 277
G + E +KE E+G G E+ KE K+ LK + E + EDD KE
Sbjct: 470 GCPKRGFEGSCSQKESEEGNPVRGSEEDSPKKESKKKTLKNDCEENGLAKESEDDLNKES 529
Query: 278 PQSI 281
+ +
Sbjct: 530 EEEV 533
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 76.3 bits (186), Expect = 3e-14
Identities = 72/256 (28%), Positives = 117/256 (45%), Gaps = 28/256 (10%)
Query: 30 VTPEVKPKRTSSSRKMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKITE 89
V P+ K K+ +++ K T AVA ++A V + A AK T
Sbjct: 47 VIPQKKGKKAAATSAKKVVVS------PTKKVAVATPAKKAAVTP--GKKAAATPAKKTV 98
Query: 90 APASEKEIVEVKEENIEDA-TEKGGEKKEAVAAE-VKNEEEDQKEDEEDQNEEKGEAGKE 147
PA K A G+K A+ A+ KN + +KED +++ ++ E
Sbjct: 99 TPAKAVTTPGKKGATPGKALVATPGKKGAAIPAKGAKNGKNAKKEDSDEEEDDDSE---- 154
Query: 148 DKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGD 207
+DE+ +ED ED ED E K + ++ E ED+++++D +E
Sbjct: 155 -EDEEDDEDEDED-------EDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDDEEDDS 206
Query: 208 GKENEDGKEKGDKKEGKDVKVK-----EDEKEREDGK-EDEGGNEEEAGKEKEDLKEEEE 261
+E + KK K V VK EDE E ED + ED+ +E++ + ED +EEEE
Sbjct: 207 EEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEE 266
Query: 262 GKEEDEIKEDDGKKEE 277
+EE+ +KE GK+++
Sbjct: 267 EEEEEPVKEAPGKRKK 282
Score = 72.0 bits (175), Expect = 5e-13
Identities = 70/269 (26%), Positives = 125/269 (46%), Gaps = 34/269 (12%)
Query: 14 QEPKRRSARLSAMLVPVTPEVK-----PKRTSSSRKMKTKSDMMEENIDTSAQAVAETKQ 68
Q+ +++A SA V V+P K P + ++ K + + T A+AV +
Sbjct: 50 QKKGKKAAATSAKKVVVSPTKKVAVATPAKKAAVTPGKKAAATPAKKTVTPAKAVTTPGK 109
Query: 69 EAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEE 128
+ A G+A + I +N ++A ++ +++E +E +EE
Sbjct: 110 KG---------ATPGKALVATPGKKGAAIPAKGAKNGKNAKKEDSDEEEDDDSE--EDEE 158
Query: 129 DQKEDEEDQNEEKGEAGK--------EDKDEKGEEDGKEDKNGNEKG--EDAKEKEDGKK 178
D ++++ED++E + A K ED+D++ +ED ++D + E E+A E K
Sbjct: 159 DDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKG 218
Query: 179 GEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKEREDG 238
+ K K EDE EEED D E++D E + + +D + +E+E+E E
Sbjct: 219 KKAAKVVPVKAKNVAEDEDEEED-----DEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPV 273
Query: 239 KEDEGGNEEEAGKEK---EDLKEEEEGKE 264
KE G ++E K+K E K++ EG E
Sbjct: 274 KEAPGKRKKEMAKQKAAPEAKKQKVEGTE 302
Score = 46.2 bits (108), Expect = 3e-05
Identities = 29/111 (26%), Positives = 53/111 (47%), Gaps = 12/111 (10%)
Query: 176 GKKGE----DGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKED 231
GKKG G NG++ K++ DE+E++D +E + E+ED E +
Sbjct: 123 GKKGAAIPAKGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAP 182
Query: 232 EKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDDGKKEEPQSIV 282
E ED ++DE +++D +EE+ EE+ ++ K ++ +V
Sbjct: 183 ASEDEDDEDDED--------DEDDDDDEEDDSEEEAMETTPAKGKKAAKVV 225
Score = 28.9 bits (63), Expect = 5.3
Identities = 19/59 (32%), Positives = 27/59 (45%), Gaps = 9/59 (15%)
Query: 217 KGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDDGKK 275
K K +G K+ KE E+ EDE +E+E E++ EE I + GKK
Sbjct: 6 KAGKNQGDPKKMAPPPKEVEEDSEDEEMSEDE---------EDDSSGEEVVIPQKKGKK 55
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 74.3 bits (181), Expect = 1e-13
Identities = 57/244 (23%), Positives = 121/244 (49%), Gaps = 13/244 (5%)
Query: 38 RTSSSRKMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNE-NAKNGEAKITEAPASEKE 96
R + + + + E+ Q +QE V E + + G+ + E E+E
Sbjct: 97 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 156
Query: 97 IVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEED 156
+V+E+ + ++G +++ +V+ +E +E E E++G+ G E +++ GE++
Sbjct: 157 -GQVREQEGQVREQEGQVREQE--GQVREQEGQVREQEGQMGEQEGQMG-EQEEQMGEQE 212
Query: 157 GKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDE---KEEEDRKETGDGKENED 213
+ K + GE ++E +K E+ G E+ +K E++ +EE+ RK+ +E E+
Sbjct: 213 EQMQKQEEQMGE---QEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEE 269
Query: 214 GKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDDG 273
+ +++ K + E E++ + +E EE+ +++E ++E+EE E E E G
Sbjct: 270 QMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQE--EQMG 327
Query: 274 KKEE 277
K+EE
Sbjct: 328 KQEE 331
Score = 70.5 bits (171), Expect = 2e-12
Identities = 51/223 (22%), Positives = 116/223 (52%), Gaps = 14/223 (6%)
Query: 53 EENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKG 112
EE + + + + +++ +E+ + + K E ++E + +EE + + E+
Sbjct: 219 EEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQM 278
Query: 113 GEKKEAVAAEVKN-EEEDQKEDEEDQNEEKGEAGKEDKDEKGEED---GKEDKNGNEKGE 168
++KE E + E+E+Q ++E+Q E+ E +E +++ E++ GK+++ E+ E
Sbjct: 279 LKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKE 338
Query: 169 DA-KEKEDGKKGEDGKGNGEDGKEKGEDE---KEEEDRKETGDGKENEDGKEKGDKKEGK 224
++KE K E+ G E+ +K E++ +EE+ RK+ ++ E+ K +++ G
Sbjct: 339 QMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMG- 397
Query: 225 DVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDE 267
E +++ + KE EE+ G++KE ++++EE E +
Sbjct: 398 -----EQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQK 435
Score = 70.1 bits (170), Expect = 2e-12
Identities = 48/240 (20%), Positives = 125/240 (52%), Gaps = 10/240 (4%)
Query: 43 RKMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKE 102
R+ + + E + + + E +++ +E+ + K E ++E V+ +E
Sbjct: 188 REQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQE 247
Query: 103 ENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKE-DK 161
E ++ E+ +++E +++ +EE +E EE ++K + +E++ + EE +E ++
Sbjct: 248 EQVQKQEEQMRKQEE----QMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEE 303
Query: 162 NGNEKGEDAKEKEDG-KKGEDGKGNGEDG----KEKGEDEKEEEDRKETGDGKENEDGKE 216
E+ E +E+E+ ++ E+ G E+ KE+ ++KE+ ++E G++ E ++
Sbjct: 304 QMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQK 363
Query: 217 KGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDDGKKE 276
+ ++ ++ ++++ E++ +E EE+ G++KE + E++E E E + + K++
Sbjct: 364 QEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQ 423
Score = 67.4 bits (163), Expect = 1e-11
Identities = 51/246 (20%), Positives = 124/246 (50%), Gaps = 14/246 (5%)
Query: 38 RTSSSRKMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNE-NAKNGEAKITEAPASEKE 96
R + + + + E+ Q +QE V E + + G+ + E E+E
Sbjct: 83 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 142
Query: 97 IVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEED 156
+V+E+ + ++G +++ +V+ +E +E E E++G+ +E + + GE++
Sbjct: 143 -GQVREQEGQVREQEGQVREQE--GQVREQEGQVREQEGQVREQEGQV-REQEGQMGEQE 198
Query: 157 GKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGED---EKEEEDRKETGDGKENED 213
G+ + + GE ++E +K E+ G E+ K E+ E+EE+ +K+ ++ E+
Sbjct: 199 GQMGEQEEQMGE---QEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEE 255
Query: 214 GKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDDG 273
K +++ + + +++E+ ++++ EE+ G+++E ++E+EE E +E+
Sbjct: 256 QMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMRE---QEEQM 312
Query: 274 KKEEPQ 279
+++E Q
Sbjct: 313 REQEEQ 318
Score = 67.0 bits (162), Expect = 2e-11
Identities = 55/252 (21%), Positives = 132/252 (52%), Gaps = 19/252 (7%)
Query: 38 RTSSSRKMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNE-NAKNGEAKITEAPASEKE 96
R + + + + E+ Q +QE V E + + G+ + E E+E
Sbjct: 125 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 184
Query: 97 IVEVKEENIEDATEKG--GEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGE 154
+V+E+ + ++G GE++E + + EE+ QK +E+Q E+ E ++ +++ GE
Sbjct: 185 -GQVREQEGQMGEQEGQMGEQEEQMGEQ---EEQMQK--QEEQMGEQEEQMRKQEEQMGE 238
Query: 155 EDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDE---KEEEDRKETGDGKEN 211
++ + K ++ + K++E +K E+ E+ + E++ ++E+ +E G++
Sbjct: 239 QEEQVQK---QEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQE 295
Query: 212 EDGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEE--GKEEDEI- 268
E +E+ ++ ++ +++E E++ + +E G EE+ ++KE + E++E K+E+++
Sbjct: 296 EQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMG 355
Query: 269 -KEDDGKKEEPQ 279
+E+ +K+E Q
Sbjct: 356 EQEEQMQKQEEQ 367
Score = 66.2 bits (160), Expect = 3e-11
Identities = 59/281 (20%), Positives = 136/281 (48%), Gaps = 24/281 (8%)
Query: 17 KRRSARLSAMLVPVTPEVKPKRTSSSRKMKTKSDMMEENIDTSAQAVAETKQEAVVEEDY 76
K +L +P+ P+ R + + + + E+ Q +QE V E
Sbjct: 35 KELKRKLETDKIPL-PQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 93
Query: 77 NE-NAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEE 135
+ + G+ + E E+E +V+E+ + ++G +++ +V+ +E +E E
Sbjct: 94 GQVREQEGQVREQEGQVREQE-GQVREQEGQVREQEGQVREQE--GQVREQEGQVREQEG 150
Query: 136 DQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKE-DGKKGEDGKGNGEDGKEKGE 194
E++G+ +++ + +E ++ G + ++ + +E +G+ GE GE ++ GE
Sbjct: 151 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGE 210
Query: 195 DEK------------EEEDRKET---GDGKENEDGKEKGDKKEGKDVKVKEDEKEREDGK 239
E+ EE+ RK+ G+ +E +E+ +K+ + ++ K++E+ RE +
Sbjct: 211 QEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMR-KQEEQMREQ-E 268
Query: 240 EDEGGNEEEAGKEKEDLKEEEE-GKEEDEIKEDDGKKEEPQ 279
E EE+ K+KE ++EE+ G++E++++E + + E +
Sbjct: 269 EQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQE 309
Score = 66.2 bits (160), Expect = 3e-11
Identities = 57/254 (22%), Positives = 129/254 (50%), Gaps = 16/254 (6%)
Query: 38 RTSSSRKMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNE-NAKNGEAKITEAPASEKE 96
R + + + + E+ Q +QE V E + + G+ E E+E
Sbjct: 146 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQE 205
Query: 97 I-VEVKEENIEDATEKGGEKKEAVAAEVKN----EEEDQKEDEEDQNEEKGEAGKEDKDE 151
+ +EE ++ E+ GE++E + + + EE+ QK++E+ Q +E+ +E++
Sbjct: 206 EQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMR 265
Query: 152 KGEEDGKEDKNG--NEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGK 209
+ EE +E + +K + +E++ G++ E + E +E+ E +E+E++ +
Sbjct: 266 EQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMRE---Q 322
Query: 210 ENEDGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEE--GKEEDE 267
E + GK++ E K+ ++ E +++ +E G EE+ K++E ++++EE K+E++
Sbjct: 323 EEQMGKQEEQMWEQKE-QMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQ 381
Query: 268 IK--EDDGKKEEPQ 279
++ E+ +K+E Q
Sbjct: 382 MRKQEEQMRKQEEQ 395
Score = 65.9 bits (159), Expect = 4e-11
Identities = 55/257 (21%), Positives = 133/257 (51%), Gaps = 15/257 (5%)
Query: 38 RTSSSRKMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNE-NAKNGEAKITEAPASEKE 96
R + + + + E+ Q +QE V E + + G+ + E E+E
Sbjct: 132 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 191
Query: 97 -IVEVKEENIEDATEKGGEKKEAVAAEVKN---EEEDQKEDEEDQNEEKGEAGKEDKDEK 152
+ +E + + E+ GE++E + + + +EE ++ EE E++ + K+++ +
Sbjct: 192 GQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQ 251
Query: 153 GEEDG--KEDKNGNEKGEDAKEKEDG--KKGEDGKGNGEDGKEKGE-DEKEEEDRKETGD 207
+E+ K+++ E+ E +E+E+ K+ E + + G+++ + E+EE+ R++
Sbjct: 252 KQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQ 311
Query: 208 GKENEDGKEKGDKKEGKDVKVKEDEKERE-DGKEDEGGNEEEAGKEKEDLKEEEE--GKE 264
+E E+ + +++ GK + ++KE+ + KE EE+ G+++E ++++EE K+
Sbjct: 312 MREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQ 371
Query: 265 EDEIK--EDDGKKEEPQ 279
E++++ E+ +K+E Q
Sbjct: 372 EEQMRKQEEQMRKQEEQ 388
Score = 62.8 bits (151), Expect = 3e-10
Identities = 59/276 (21%), Positives = 141/276 (51%), Gaps = 29/276 (10%)
Query: 14 QEPKRRSARLSAMLVPVTPEVKPKRTSSSRKMKTKSDMMEENIDTSAQAVAETKQEAVVE 73
+E K ++A L L V E K + +++K K + + I + ++ V E
Sbjct: 7 EELKEKNAELQEELQLVETE-KSEIQLHIKELKRKLET--DKIPLPQEGQVREQEGQVRE 63
Query: 74 EDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKED 133
++ + G+ + E E+E +V+E+ + ++G +V+ +E +E
Sbjct: 64 QEGQVREQEGQVREQEGQVREQE-GQVREQEGQVREQEG---------QVREQEGQVREQ 113
Query: 134 EEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKG 193
E E++G+ ++++G+ +E + ++G+ +E+E + ++G+ ++G+ +
Sbjct: 114 EGQVREQEGQV----REQEGQVREQEGQVREQEGQ-VREQEGQVREQEGQVREQEGQVRE 168
Query: 194 ED----EKEEEDRKETGDGKENED--GKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEE 247
++ E+E + R++ G +E E G+++G E ++ ++ E E++ + +E G EE
Sbjct: 169 QEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGE-QEEQMGEQEEQMQKQEEQMGEQEE 227
Query: 248 EAGKEKEDLKEEEE--GKEEDEI--KEDDGKKEEPQ 279
+ K++E + E+EE K+E+++ +E+ +K+E Q
Sbjct: 228 QMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQ 263
Score = 57.0 bits (136), Expect = 2e-08
Identities = 43/186 (23%), Positives = 85/186 (45%), Gaps = 7/186 (3%)
Query: 37 KRTSSSRKMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKITEAPASEKE 96
K+ RK + + EE + + + + K++ EE E + + + E++
Sbjct: 252 KQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQ 311
Query: 97 IVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGE-----AGKEDKDE 151
+ E +E+ E + G K+E E K + +QKE Q E+ GE +E++
Sbjct: 312 MREQEEQMREQEEQMG--KQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVR 369
Query: 152 KGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKEN 211
K EE ++ + K E+ K++ + GE + GE ++ E E++ ++KE +E
Sbjct: 370 KQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEE 429
Query: 212 EDGKEK 217
G++K
Sbjct: 430 HMGEQK 435
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 73.9 bits (180), Expect = 1e-13
Identities = 63/233 (27%), Positives = 113/233 (48%), Gaps = 35/233 (15%)
Query: 77 NENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEED 136
N+ A+N + E S +E E++E + K +K + AE +E+ +KE+EE+
Sbjct: 139 NDTAENETTEKEEKSESRQERYEIEET---ETVTKSYQKNDWRDAEENKKEDKEKEEEEE 195
Query: 137 QNEEKGEAGKEDKDEKGEEDGKED---------KNGNEKGEDAKEKEDGKKGEDGKGNGE 187
+ ++G G+ + EE E KNG E+ K++E+ ++G D + E
Sbjct: 196 EKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHE 255
Query: 188 ----DGKEKGEDEK-----EEEDR------KETGDGKENEDGKEKGDKKEGKDVKVKEDE 232
+ KE+ E E+ EE +R K+ D + + +EK +E + + +E E
Sbjct: 256 KMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERE 315
Query: 233 KEREDGK----EDEGGNEEE--AGKEKEDLKEEEE--GKEEDEIKEDDGKKEE 277
+ RE+ K E + EEE A +E++ +KEEE+ +E IKE++ + E
Sbjct: 316 RMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAE 368
Score = 73.6 bits (179), Expect = 2e-13
Identities = 70/289 (24%), Positives = 130/289 (44%), Gaps = 23/289 (7%)
Query: 12 MRQEPKRRSARLSAMLVPVTPEVKPKRTSSSRKMKTKSDMME--ENIDTSAQAVAETKQE 69
+ + +RR RL L E P T +S + ++ + EN T + +E++QE
Sbjct: 100 LARREERRQKRLQEALER-QKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQE 158
Query: 70 AVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKG--GEKKEAVAAEVKNEE 127
E+ K+ + K+ + KEE E+ ++G GE + V E K E
Sbjct: 159 RYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTE 218
Query: 128 EDQK-----------EDEEDQNEEKGEAGKED--KDEKGEEDGKEDKNGNEKGEDAKEKE 174
++ EE + EE+ E G ++ EK EE+ KE +A+E+E
Sbjct: 219 SQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERE 278
Query: 175 DGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKE 234
K +D K E + + E++ ++R E + +E E +E+ + + ++KE+EK
Sbjct: 279 RIKAEQDKKIADERARIEAEEKAAAQER-ERREAEERERMREEEKRAAEERQRIKEEEKR 337
Query: 235 REDGKEDEGGNEEEAGKEKEDLKEEE----EGKEEDEIKEDDGKKEEPQ 279
+ ++ E+ A +E++ +KEEE E ++ +E++ K E Q
Sbjct: 338 AAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQ 386
Score = 67.0 bits (162), Expect = 2e-11
Identities = 60/249 (24%), Positives = 118/249 (47%), Gaps = 25/249 (10%)
Query: 38 RTSSSRKMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKITEAPASEKEI 97
R + K + K EE ++ E + E +VEE K TE+ E +
Sbjct: 178 RDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEE-----------KTTES-QEETVV 225
Query: 98 VEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDE-KGEED 156
+ +K I K E++E + E+ + E+ ++ED+E E+ E+++ K E+D
Sbjct: 226 MSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQD 285
Query: 157 GK-EDKNGNEKGED---AKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENE 212
K D+ + E+ A+E+E + E + E+ + E ++ +E+ K + ++
Sbjct: 286 KKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRI 345
Query: 213 DGKEKGDKKEGKDVKVKE----DEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEI 268
+EK +E + +K +E +E++R +E+E EE + K+ L+E++ +E +I
Sbjct: 346 KEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQ-LEEKKHAMQETKI 404
Query: 269 KEDDGKKEE 277
K G+K E
Sbjct: 405 K---GEKVE 410
Score = 66.2 bits (160), Expect = 3e-11
Identities = 62/264 (23%), Positives = 130/264 (49%), Gaps = 25/264 (9%)
Query: 32 PEVKPKRTSSSRKMKTKSDMMEENIDTS----AQAVAETKQEAVVEEDYNENAKNGEAKI 87
P+ + +R S ++ M EE+ + + A+ AE ++ E+D + +
Sbjct: 238 PKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEA 297
Query: 88 TE-APASEKEIVEVKE-ENIEDATEKGGEKKEAVAAEVKNE-EEDQKEDEEDQ------- 137
E A A E+E E +E E + + ++ E+++ + E K EE Q+ EE++
Sbjct: 298 EEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQ 357
Query: 138 --NEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGE- 194
EE+ A +E + + EE+ K ++ + +EK+ + KG + K +G+
Sbjct: 358 RIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKW 417
Query: 195 --DEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEK--EREDGKEDEGGNEEEAG 250
++K +ED+ +T K + G+EKG K + K K++ED+ ++E+ K+++ ++E
Sbjct: 418 VNEKKAQEDKLQTAVLK--KQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPK 475
Query: 251 KEKEDLKEEEEGKEEDEIKEDDGK 274
+E + + ++G E+K +G+
Sbjct: 476 EEVKSFMDRKKG--FTEVKSQNGE 497
Score = 62.4 bits (150), Expect = 4e-10
Identities = 72/305 (23%), Positives = 127/305 (41%), Gaps = 45/305 (14%)
Query: 3 KRKAAGQGDMRQEPKRRSA---RLSAMLVPVTPEVKPKRTSSSRKMKTKSDMMEENIDTS 59
KR A + +++E KR + R+ E + R K K + + ++
Sbjct: 336 KRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEK 395
Query: 60 AQAVAETK---------------QEAVVEEDYNENA---KNGEAKITEAPASEKEIVEVK 101
A+ ETK E +ED + A K GE K T+ V+ K
Sbjct: 396 KHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTK--------VQAK 447
Query: 102 EENIEDATEKGGEKKEAVAAE-VKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGE------ 154
E +++ +K KKE + E +K ++E ++E + + +KG E K + GE
Sbjct: 448 REKLQE--DKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFT--EVKSQNGEFMTHKL 503
Query: 155 --EDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENE 212
+ + G D KE E + E GK E + +GE E EE ++ + K+ E
Sbjct: 504 KHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQ---KQQE 560
Query: 213 DGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDD 272
E + K+ ++ + K E+E + K++E + +EK LKEE E + + ++
Sbjct: 561 AALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQ 620
Query: 273 GKKEE 277
E+
Sbjct: 621 KMPED 625
Score = 59.7 bits (143), Expect = 3e-09
Identities = 77/308 (25%), Positives = 122/308 (39%), Gaps = 46/308 (14%)
Query: 12 MRQEPKRRSARLSAMLVPVTPEVKPKRTSSSRKMKTKSDMMEENIDTSAQAVAETKQEAV 71
M +E K R+ A L E R + + K + + A A ++EA
Sbjct: 257 MEEEDKERAEAERARLEAEERE----RIKAEQDKKIADERARIEAEEKAAAQERERREAE 312
Query: 72 VEEDYNENAKNGEAKITEAPASEKEIVE----VKEENIEDATEKGGEKKEAV-AAEVK-- 124
E E K + EK E +KEE A E+ K+E AAE +
Sbjct: 313 ERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQR 372
Query: 125 ---NEEEDQKEDEEDQN---EEKGEAGKEDK----------------DEKGEEDGKEDKN 162
EEE K +E+ +N EEK A +E K ++K +ED +
Sbjct: 373 ARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAV 432
Query: 163 GNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKE-----K 217
++GE+ K K+ + + KE+ +DEK ++D++ + K D K+ K
Sbjct: 433 LKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVK 492
Query: 218 GDKKEGKDVKVKEDE--------KEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIK 269
E K+K E + D KE EG + EAGK E+L+ E +E +
Sbjct: 493 SQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFE 552
Query: 270 EDDGKKEE 277
+ K++E
Sbjct: 553 KLKQKQQE 560
Score = 52.8 bits (125), Expect = 3e-07
Identities = 69/290 (23%), Positives = 130/290 (44%), Gaps = 28/290 (9%)
Query: 3 KRKAAGQGDMRQEPKRRSARLSAMLVPVTPEVKPKRTSSSRKMKTKSDMMEENIDTSAQA 62
+R+A + MR+E KR + + + + KR + R+ + K + E+ Q
Sbjct: 308 RREAEERERMREEEKRAAEERQRI------KEEEKRAAEERQ-RIKEE--EKRAAEERQR 358
Query: 63 VAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAE 122
+ E ++ A E + +AK+ E +++ +E K+ +++ KG + ++ + +
Sbjct: 359 IKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQ--LEEKKHAMQETKIKGEKVEQKIEGK 416
Query: 123 VKNEEEDQKEDEED-----QNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGK 177
NE++ Q++ + Q EEKG + K EK +ED K E+ +D K K+D +
Sbjct: 417 WVNEKKAQEDKLQTAVLKKQGEEKGTK-VQAKREKLQEDKPTFKK--EEIKDEKIKKDKE 473
Query: 178 KGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKERED 237
E+ K + D K+ + K + T K E+ + + D K E + E
Sbjct: 474 PKEEVK-SFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEA 532
Query: 238 GKEDE-----GGNEEEAGKEKEDLKEEEEGKEEDEIKEDDGKKEEPQSIV 282
GK E G E EK K++E E +E+K+ K+EE + ++
Sbjct: 533 GKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKK---KREERRKVL 579
Score = 40.8 bits (94), Expect = 0.001
Identities = 51/261 (19%), Positives = 109/261 (41%), Gaps = 28/261 (10%)
Query: 31 TPEVKPKRTSSSRKMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKITEA 90
T +K + K++ K + ++E+ T K+E + +E ++ K + ++
Sbjct: 430 TAVLKKQGEEKGTKVQAKREKLQEDKPTF-------KKEEIKDEKIKKD-KEPKEEVKSF 481
Query: 91 PASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKD 150
+K EVK +N E T K + + D KE E E G+ +E +
Sbjct: 482 MDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRR 541
Query: 151 EKGEEDGKEDKNGNEKGEDA--------KEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDR 202
+GE + +E + +K ++A K++E+ +K + + +E +EEE++
Sbjct: 542 RRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEK 601
Query: 203 KETGDGKENEDGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEG 262
+ KE+ +++ + ++ +K EDG D+ + + LK EE
Sbjct: 602 RRL---------KEEIERRRAE--AAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERA 650
Query: 263 K-EEDEIKEDDGKKEEPQSIV 282
+ +++ G K Q+ +
Sbjct: 651 EFLNKSVQKSSGVKSTHQAAI 671
Score = 29.3 bits (64), Expect = 4.1
Identities = 25/94 (26%), Positives = 43/94 (45%), Gaps = 8/94 (8%)
Query: 41 SSRKMKTKSDMMEENIDTSAQAVAETKQEAVVE------EDYNENAKNGE-AKITEAPAS 93
SS K++ +++ + +++ S+ V T Q A+V E Y + + AK T+ AS
Sbjct: 642 SSLKIEERAEFLNKSVQKSS-GVKSTHQAAIVSKIDSRLEQYTSAIEGTKSAKPTKPAAS 700
Query: 94 EKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEE 127
+ + NI+ EKG AA N+E
Sbjct: 701 DLPVPAEGVRNIKSMWEKGNVFSSPTAAGTPNKE 734
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 73.6 bits (179), Expect = 2e-13
Identities = 53/240 (22%), Positives = 123/240 (51%), Gaps = 14/240 (5%)
Query: 44 KMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEV--K 101
KM+ + +MM E + + + ++ + E E + E KI E +++ ++ +
Sbjct: 425 KMRRQEEMMWEKEEKIRELEEKMHEQEKIRE--QEEKRQEEEKIREQEKRQEQEAKMWRQ 482
Query: 102 EENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDK 161
EE I + EK E++E + + + E +K EE++ +E+ E ++++ + +E+ K
Sbjct: 483 EEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQK 542
Query: 162 NGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKK 221
+ E+ K++ K +EK D++E+ +E ++ E +E+ +K
Sbjct: 543 EKIHEQEEKIRKQEEKMWRQ--------EEKMHDQEEKIREQEEKVWRQEEKIREQEEKI 594
Query: 222 EGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEE--GKEEDEIKEDDGKKEEPQ 279
++ K++E E+ ++ +E G EE+ +++E ++E+EE ++E++I+E + K E +
Sbjct: 595 REQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQE 654
Score = 63.9 bits (154), Expect = 1e-10
Identities = 70/282 (24%), Positives = 141/282 (50%), Gaps = 27/282 (9%)
Query: 14 QEPKRRSARLSAMLVPVTPEVKP--------KRTSSSRKMKTKSDMMEENIDTSAQAV-- 63
+E K ++A+L L V E KR K+ ++ D + +
Sbjct: 278 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 337
Query: 64 AETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEV 123
K +A VEE+ N N + + E ++E ++ EE I++ EK E++E ++
Sbjct: 338 VSAKLQAQVEENELWNRLNQQQE--EKMWRQEEKIQEWEEKIQEQEEKIREQEE----KI 391
Query: 124 KNEEEDQKEDEED--QNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGED 181
+ +EE + EE + EEK +E EK E+ ++++ EK E +E E+ K E
Sbjct: 392 REQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEE-KMHEQ 450
Query: 182 GKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKEREDGK-- 239
K ++ K + E++ E+++++ + K +E+ +++ + ++ +E++ R++ K
Sbjct: 451 EKIREQEEKRQEEEKIREQEKRQEQEAKMWR--QEEKIREQEEKIREQEEKMWRQEEKIH 508
Query: 240 EDEGGNEEEAGKEKEDL-KEEEEGKEEDEI---KEDDGKKEE 277
E E EEE +E+E++ ++EE+ +E++EI KE ++EE
Sbjct: 509 EQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEE 550
Score = 59.7 bits (143), Expect = 3e-09
Identities = 54/242 (22%), Positives = 119/242 (49%), Gaps = 11/242 (4%)
Query: 33 EVKPKRTSSSRKMKTKSDMMEENIDTSAQAVAETKQEAV-VEEDYNENAKNGEAKITEAP 91
E K + ++ + K EE I + + E +++ EE +E K E E
Sbjct: 463 EEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIRE----EEK 518
Query: 92 ASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQK---EDEEDQNEEKGEAGKED 148
E+E + +EE I + E +K++ E K ++++K ++E+ ++E+ +E+
Sbjct: 519 RQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEE 578
Query: 149 KDEKGEEDGKEDKNG-NEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGD 207
K + EE +E + E+ E +E+E+ + ++ K ++ K ++EK +E ++
Sbjct: 579 KVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMR- 637
Query: 208 GKENEDGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDE 267
++ E +E+ K ++ K++E E+ ++ +E EE+ +++E ++E+EE E
Sbjct: 638 -RQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQE 696
Query: 268 IK 269
K
Sbjct: 697 EK 698
Score = 59.3 bits (142), Expect = 4e-09
Identities = 57/297 (19%), Positives = 143/297 (48%), Gaps = 22/297 (7%)
Query: 3 KRKAAGQGDMRQEPKRRSARLSAMLVPVTPEVKPKRT---SSSRKMKTKSDMMEENIDTS 59
+ K Q +M E + + R M+ +++ + K++ + M E
Sbjct: 395 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIR 454
Query: 60 AQAVAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAV 119
Q ++E + E++ + + + E ++E + +EE + EK E+++
Sbjct: 455 EQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIR 514
Query: 120 AAEVKNEEED--------QKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAK 171
E + E+E+ ++++E + +EK +E ++ E+ ++++ +++ E +
Sbjct: 515 EEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIR 574
Query: 172 EKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGD-----GKENEDGKEKGDKKEGKDV 226
E+E+ ++ K ++ K + ++EK E + T + G++ E E+ +K + ++
Sbjct: 575 EQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEE 634
Query: 227 KV-KEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGK---EEDEIKEDDGKKEEPQ 279
K+ +++EK RE K+ +EE +E+E++ +E+E K +E+++ E + K +E +
Sbjct: 635 KMRRQEEKIREQEKKIR--EQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQE 689
Score = 55.5 bits (132), Expect = 5e-08
Identities = 64/296 (21%), Positives = 141/296 (47%), Gaps = 33/296 (11%)
Query: 1 MPKRKAAGQGD-MRQEPKRRSARLSAMLVPVTPEVKPKRTSSSRKMKTKSDMMEENIDTS 59
+P+++ + D + +E + SA+L A + E +++ + K EE I
Sbjct: 319 LPQQQLQAEADHLGKELQSVSAKLQAQV-----EENELWNRLNQQQEEKMWRQEEKIQEW 373
Query: 60 AQAVAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAV 119
+ + E ++E + E++ E + E K+ ++E++ KEE + E EK+E
Sbjct: 374 EEKIQE-QEEKIREQE--EKIREQEEKMRR----QEEMMWEKEEKMRRQEEMMWEKEE-- 424
Query: 120 AAEVKNEEEDQKEDEEDQNEEKGEAGKEDK----DEKGEEDGKEDKNGNEKGEDAK---- 171
+++ +EE E EE E + + +++K +EK +E+ K + + ++AK
Sbjct: 425 --KMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQ 482
Query: 172 ------EKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKD 225
++E ++ E+ E+ + E +EEE R+E + E+ + ++ +
Sbjct: 483 EEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQK 542
Query: 226 VKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEE--GKEEDEIKEDDGKKEEPQ 279
K+ E E++ +E EE+ ++E ++E+EE ++E++I+E + K E +
Sbjct: 543 EKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQE 598
Score = 52.8 bits (125), Expect = 3e-07
Identities = 52/237 (21%), Positives = 109/237 (45%), Gaps = 7/237 (2%)
Query: 37 KRTSSSRKMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKITEAPASEKE 96
++ K++ + E+ Q +QE + E E E KI E +E
Sbjct: 458 EKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQ-EEKMWRQEEKIHEQEKIREE 516
Query: 97 IVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEE--KGEAGKEDKDEKGE 154
++E + EK E++E + K E+++K Q E+ + E D++EK
Sbjct: 517 EKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKI--RKQEEKMWRQEEKMHDQEEKIR 574
Query: 155 EDGKEDKNGNEKGEDAKEK--EDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENE 212
E ++ EK + +EK E +K + + ++ +EK +++E+ +E ++ E
Sbjct: 575 EQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEE 634
Query: 213 DGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIK 269
+ + +K ++ K++E E++ + +E EE+ +++E + E+EE +E E K
Sbjct: 635 KMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEK 691
Score = 52.4 bits (124), Expect = 4e-07
Identities = 55/235 (23%), Positives = 117/235 (49%), Gaps = 14/235 (5%)
Query: 43 RKMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKN---GEAKITEAPA--SEKEI 97
R+ + K EE + + + E QE + EE+ + + E KI E +KE
Sbjct: 487 REQEEKIREQEEKMWRQEEKIHE--QEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEK 544
Query: 98 VEVKEENIEDATEKGGEKKEAVA-AEVKNEEEDQK----EDEEDQNEEKGEAGKEDKDEK 152
+ +EE I EK ++E + E K E+++K E++ + EEK +E E+
Sbjct: 545 IHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQ 604
Query: 153 GEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENE 212
E ++++ E+ E E+E+ + ++ K ++ K + E EK+ +++E ++ E
Sbjct: 605 EEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIR-EQEKKIREQEEK-IREQEE 662
Query: 213 DGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDE 267
+E+ +K ++ K+ E E++ ++ +E EE+ +++ L+++EE +E +
Sbjct: 663 MMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQ 717
Score = 42.7 bits (99), Expect = 4e-04
Identities = 40/194 (20%), Positives = 101/194 (52%), Gaps = 16/194 (8%)
Query: 53 EENIDTSAQAVAETKQEAVVEED----YNENAKNGEAKITEAPASEKEIVEVKEENIEDA 108
+E I + + E +++ +E+ E + E KI E ++E V +EE I +
Sbjct: 535 QEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIRE----QEEKVWRQEEKIREQ 590
Query: 109 TEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGE 168
EK E++E + E + ++Q+E +Q E+ E +E E+ E+ ++++ E+ +
Sbjct: 591 EEKIREQEEKIR-EQEEMTQEQEEKMGEQEEKMCEQ-EEKMQEQEEKMRRQEEKIREQEK 648
Query: 169 DAKEKEDGKKGEDGKGNGEDGKEKGEDEK--EEEDRKETGDGKENEDGKEKGDKKEGKDV 226
+E+E+ + ++ ++ K ++EK E+E++ + ++ E + + +K ++V
Sbjct: 649 KIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQ----EQEEKMRRQEEKMWEQEV 704
Query: 227 KVKEDEKEREDGKE 240
++++ E++ ++ +E
Sbjct: 705 RLRQQEEKMQEHQE 718
Score = 32.3 bits (72), Expect = 0.48
Identities = 24/130 (18%), Positives = 62/130 (47%), Gaps = 7/130 (5%)
Query: 33 EVKPKRTSSSRKMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKITEAPA 92
E + K K++ + +M +E + + + ++ ++ E + E KI E
Sbjct: 589 EQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEK 648
Query: 93 S---EKEIVEVKEENIEDATEKGGEKKEAVAAEVKN----EEEDQKEDEEDQNEEKGEAG 145
++E + +EE +++ EK E++E + + + EE+ ++++E+ +E
Sbjct: 649 KIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQ 708
Query: 146 KEDKDEKGEE 155
+E+K ++ +E
Sbjct: 709 QEEKMQEHQE 718
>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
Length = 1184
Score = 72.8 bits (177), Expect = 3e-13
Identities = 53/165 (32%), Positives = 84/165 (50%), Gaps = 27/165 (16%)
Query: 126 EEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGN 185
++ D ED +++ E++GE ED DE G+ED +ED+ G+ + E+ E+ED ED +
Sbjct: 91 DDSDGTEDMDEKEEDEGEEYSEDNDEPGDED-EEDEEGDREEEEEIEEED----EDDDED 145
Query: 186 GEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGN 245
GED +++ E+E+EEE+ +E +ENED + + ++ +D E++D DE N
Sbjct: 146 GEDVEDEEEEEEEEEEEEEE---EENED-----HQMNCHNTRIMQD-TEKDDNNNDEYDN 196
Query: 246 EEE--------AGKEKEDL-----KEEEEGKEEDEIKEDDGKKEE 277
+E GK ED E E EDD K E
Sbjct: 197 YDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKNE 241
Score = 56.2 bits (134), Expect = 3e-08
Identities = 39/101 (38%), Positives = 55/101 (54%), Gaps = 21/101 (20%)
Query: 181 DGKGNGEDGKEKGEDEKEE--EDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKEREDG 238
D ED EK EDE EE ED E GD E + E+GD++E E+E E ED
Sbjct: 91 DDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEED---EEGDREE-------EEEIEEEDE 140
Query: 239 KEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDDGKKEEPQ 279
+DE G ED+++EEE +EE+E +E++ + E+ Q
Sbjct: 141 DDDEDG---------EDVEDEEEEEEEEEEEEEEEENEDHQ 172
Score = 55.5 bits (132), Expect = 5e-08
Identities = 36/177 (20%), Positives = 80/177 (45%), Gaps = 1/177 (0%)
Query: 90 APASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDK 149
AP + V+ ++++ + G + E + EE + DE +E+ E G ++
Sbjct: 72 APKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREE 131
Query: 150 DEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGK 209
+E+ EE+ ++D E ED +E+E+ ++ E+ + ED + + + +D ++ +
Sbjct: 132 EEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNN 191
Query: 210 ENEDGKEKGDKKEGKDV-KVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEE 265
+ D ++ K ++ K+ ED R + + N + ++ D E K E
Sbjct: 192 DEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKNENLGRKSE 248
Score = 52.0 bits (123), Expect = 6e-07
Identities = 29/80 (36%), Positives = 49/80 (61%), Gaps = 4/80 (5%)
Query: 201 DRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEE 260
D + DG E+ D KE + EG++ DE ED +++EG EEE E+ED ++E
Sbjct: 88 DECDDSDGTEDMDEKE---EDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDE 144
Query: 261 EGKE-EDEIKEDDGKKEEPQ 279
+G++ EDE +E++ ++EE +
Sbjct: 145 DGEDVEDEEEEEEEEEEEEE 164
Score = 51.2 bits (121), Expect = 1e-06
Identities = 45/185 (24%), Positives = 80/185 (43%), Gaps = 25/185 (13%)
Query: 31 TPEVKPKRTSSSRK---MKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKI 87
T + +P+ + RK +K S ++E D+ + K+E EE +N + G+
Sbjct: 63 TQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDE 122
Query: 88 TEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNE-------- 139
+ +E EE IE+ E E E V E + EEE+++E+EE++NE
Sbjct: 123 EDEEGDREE-----EEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHN 177
Query: 140 -------EKGEAGKEDKDEKGEEDGKEDKNGNEKGEDA--KEKEDGKKGEDGKGNGEDGK 190
EK + ++ D E K N + EDA + + + + + + ED
Sbjct: 178 TRIMQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDS 237
Query: 191 EKGED 195
+K E+
Sbjct: 238 DKNEN 242
Score = 42.0 bits (97), Expect = 6e-04
Identities = 42/196 (21%), Positives = 82/196 (41%), Gaps = 20/196 (10%)
Query: 42 SRKMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVK 101
++K KT+ +E + +V E D ++ ++ + K E E+ +
Sbjct: 58 AKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEK--EEDEGEEYSEDND 115
Query: 102 EENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEED----QNEEKGEAGKEDKDEKGE--- 154
E ED ++ G+++E E++ E+ED ED ED + EE+ E +E+++E +
Sbjct: 116 EPGDEDEEDEEGDREEE--EEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQM 173
Query: 155 --------EDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETG 206
+D ++D N N++ ++ E GK ED + E E
Sbjct: 174 NCHNTRIMQDTEKDDNNNDEYDNYDELVAKSLLNLGK-IAEDAAYRARTESEMNSNTSNS 232
Query: 207 DGKENEDGKEKGDKKE 222
+++ + G K E
Sbjct: 233 LEDDSDKNENLGRKSE 248
Score = 40.8 bits (94), Expect = 0.001
Identities = 30/97 (30%), Positives = 52/97 (53%), Gaps = 11/97 (11%)
Query: 190 KEKGEDEKEEED--RKETGDGKENEDGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEE 247
K K +D++ +E +++ K + ++ D +G + DEKE ++G+E N+E
Sbjct: 60 KRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTE---DMDEKEEDEGEEYSEDNDE 116
Query: 248 EAGKEKE-----DLKEEEEGKEEDEIKEDDGKKEEPQ 279
G E E D +EEEE +EEDE ++DG+ E +
Sbjct: 117 P-GDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDE 152
>gi|190014588 PC4 and SFRS1 interacting protein 1 isoform 2 [Homo
sapiens]
Length = 530
Score = 72.4 bits (176), Expect = 4e-13
Identities = 62/243 (25%), Positives = 108/243 (44%), Gaps = 19/243 (7%)
Query: 3 KRKAAGQGDMRQEPKRRSARLSAMLVPVTPEVKPKRTSSSRKMKTKSDMMEENIDTSAQA 62
K + + D E K + ++ + TP K R RK + + + E + T+A A
Sbjct: 113 KETSVSKEDTDHEEKASNEDVTKAVDITTP--KAARRGRKRKAEKQVETEEAGVVTTATA 170
Query: 63 VAETKQEAVVEEDYNENAK----NGEAKITEAPA-SEKEIVEVKEENIEDATEKGGEKKE 117
K K G K+ + P SE +I+ ED ++K G++++
Sbjct: 171 SVNLKVSPKRGRPAATEVKIPKPRGRPKMVKQPCPSESDIITE-----EDKSKKKGQEEK 225
Query: 118 AVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGK 177
+ K +EE QKE+++ + E + GK++ + K + K E+ + ++G+
Sbjct: 226 QPKKQPKKDEEGQKEEDKPRKEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEGDDQEGE 285
Query: 178 KGEDGKGNGEDGKE----KGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEK 233
K G N + KG+ EKE DRK +E + E+ +K EGK +VK+ EK
Sbjct: 286 KKRKGGRNFQTAHRRNMLKGQHEKEAADRKRK---QEEQMETEQQNKDEGKKPEVKKVEK 342
Query: 234 ERE 236
+RE
Sbjct: 343 KRE 345
Score = 59.3 bits (142), Expect = 4e-09
Identities = 66/273 (24%), Positives = 119/273 (43%), Gaps = 47/273 (17%)
Query: 36 PKRTSSSRKMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKITEAPASEK 95
PK SS++ TK +++ + + +K++ EE + IT A+ +
Sbjct: 88 PKVKFSSQQAATKQSNASSDVEVEEKETSVSKEDTDHEEKASNEDVTKAVDITTPKAARR 147
Query: 96 EIVEVKEENIEDATEKGG---------------EKKEAVAAEVK--NEEEDQKEDEEDQN 138
E+ +E TE+ G ++ A EVK K ++
Sbjct: 148 GRKRKAEKQVE--TEEAGVVTTATASVNLKVSPKRGRPAATEVKIPKPRGRPKMVKQPCP 205
Query: 139 EEKGEAGKEDKDEK-GEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEK 197
E +EDK +K G+E+ K+ K +K E+ +++ED + E K G K E E
Sbjct: 206 SESDIITEEDKSKKKGQEE-KQPKKQPKKDEEGQKEEDKPRKEPDKKEG-----KKEVES 259
Query: 198 EEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKEREDGKEDE---------GGNEEE 248
+ ++ +TG D +E+GD +EG EK+R+ G+ + G +E+E
Sbjct: 260 KRKNLAKTG-VTSTSDSEEEGDDQEG--------EKKRKGGRNFQTAHRRNMLKGQHEKE 310
Query: 249 AGKEKEDLKEEEEGKEEDEIKEDDGKKEEPQSI 281
A K +++EE E ++ +D+GKK E + +
Sbjct: 311 AADRK---RKQEEQMETEQQNKDEGKKPEVKKV 340
Score = 39.3 bits (90), Expect = 0.004
Identities = 49/205 (23%), Positives = 90/205 (43%), Gaps = 22/205 (10%)
Query: 6 AAGQGDMRQEPKRRSARLSAMLVPVTPEVKPKRTSSSRKMKTKSDMMEENIDTSAQAVAE 65
A +++ PKR + + +P P +PK + ++SD++ E D S + E
Sbjct: 168 ATASVNLKVSPKRGRPAATEVKIP-KPRGRPKMVK--QPCPSESDIITEE-DKSKKKGQE 223
Query: 66 TKQEAVVEEDYNENAKNGEAKITEAPASE-KEIVEVKEENIEDATEKGGEKKEAVAAEVK 124
KQ + E K + E E K+ VE K +N+ K V +
Sbjct: 224 EKQPKKQPKKDEEGQKEEDKPRKEPDKKEGKKEVESKRKNLA---------KTGVTSTSD 274
Query: 125 NEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKG 184
+EEE +D+E + + KG + + G+ +K + D K K++ ++ E +
Sbjct: 275 SEEEG--DDQEGEKKRKGGRNFQTAHRRNMLKGQHEK----EAADRKRKQE-EQMETEQQ 327
Query: 185 NGEDGKEKGEDEKEEEDRKETGDGK 209
N ++GK K E +K E+ R+ + D +
Sbjct: 328 NKDEGK-KPEVKKVEKKRETSMDSR 351
Score = 36.6 bits (83), Expect = 0.025
Identities = 24/98 (24%), Positives = 51/98 (52%), Gaps = 12/98 (12%)
Query: 117 EAVAAEVKNEE--EDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKE 174
++V +V N+ E ++ +E ++ +++G+ G K EK E+ G + NG G DA++
Sbjct: 433 DSVITQVLNKSLAEQRQHEEANKTKDQGKKGPNKKLEK-EQTGSKTLNG---GSDAQD-- 486
Query: 175 DGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENE 212
G + NGE ++ ++ + +K + + +E E
Sbjct: 487 ----GNQPQHNGESNEDSKDNHEASTKKKPSSEERETE 520
Score = 28.5 bits (62), Expect = 6.9
Identities = 18/78 (23%), Positives = 37/78 (47%), Gaps = 5/78 (6%)
Query: 203 KETGDGKENEDGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEG 262
K + +++E+ + D +GK K+ EKE+ K GG++ + G + + E
Sbjct: 442 KSLAEQRQHEEANKTKD--QGKKGPNKKLEKEQTGSKTLNGGSDAQDGNQPQ---HNGES 496
Query: 263 KEEDEIKEDDGKKEEPQS 280
E+ + + K++P S
Sbjct: 497 NEDSKDNHEASTKKKPSS 514
Score = 28.1 bits (61), Expect = 9.0
Identities = 25/108 (23%), Positives = 43/108 (39%), Gaps = 19/108 (17%)
Query: 153 GEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENE 212
GE D + N+ + ++ E+ K +D G+ G K + EKE+ K G + +
Sbjct: 430 GEGDSVITQVLNKSLAEQRQHEEANKTKD---QGKKGPNK-KLEKEQTGSKTLNGGSDAQ 485
Query: 213 DGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEE 260
DG + + + ED N E + K+K +E E
Sbjct: 486 DGNQP---------------QHNGESNEDSKDNHEASTKKKPSSEERE 518
>gi|19923653 PC4 and SFRS1 interacting protein 1 isoform 2 [Homo
sapiens]
Length = 530
Score = 72.4 bits (176), Expect = 4e-13
Identities = 62/243 (25%), Positives = 108/243 (44%), Gaps = 19/243 (7%)
Query: 3 KRKAAGQGDMRQEPKRRSARLSAMLVPVTPEVKPKRTSSSRKMKTKSDMMEENIDTSAQA 62
K + + D E K + ++ + TP K R RK + + + E + T+A A
Sbjct: 113 KETSVSKEDTDHEEKASNEDVTKAVDITTP--KAARRGRKRKAEKQVETEEAGVVTTATA 170
Query: 63 VAETKQEAVVEEDYNENAK----NGEAKITEAPA-SEKEIVEVKEENIEDATEKGGEKKE 117
K K G K+ + P SE +I+ ED ++K G++++
Sbjct: 171 SVNLKVSPKRGRPAATEVKIPKPRGRPKMVKQPCPSESDIITE-----EDKSKKKGQEEK 225
Query: 118 AVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGK 177
+ K +EE QKE+++ + E + GK++ + K + K E+ + ++G+
Sbjct: 226 QPKKQPKKDEEGQKEEDKPRKEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEGDDQEGE 285
Query: 178 KGEDGKGNGEDGKE----KGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEK 233
K G N + KG+ EKE DRK +E + E+ +K EGK +VK+ EK
Sbjct: 286 KKRKGGRNFQTAHRRNMLKGQHEKEAADRKRK---QEEQMETEQQNKDEGKKPEVKKVEK 342
Query: 234 ERE 236
+RE
Sbjct: 343 KRE 345
Score = 59.3 bits (142), Expect = 4e-09
Identities = 66/273 (24%), Positives = 119/273 (43%), Gaps = 47/273 (17%)
Query: 36 PKRTSSSRKMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKITEAPASEK 95
PK SS++ TK +++ + + +K++ EE + IT A+ +
Sbjct: 88 PKVKFSSQQAATKQSNASSDVEVEEKETSVSKEDTDHEEKASNEDVTKAVDITTPKAARR 147
Query: 96 EIVEVKEENIEDATEKGG---------------EKKEAVAAEVK--NEEEDQKEDEEDQN 138
E+ +E TE+ G ++ A EVK K ++
Sbjct: 148 GRKRKAEKQVE--TEEAGVVTTATASVNLKVSPKRGRPAATEVKIPKPRGRPKMVKQPCP 205
Query: 139 EEKGEAGKEDKDEK-GEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEK 197
E +EDK +K G+E+ K+ K +K E+ +++ED + E K G K E E
Sbjct: 206 SESDIITEEDKSKKKGQEE-KQPKKQPKKDEEGQKEEDKPRKEPDKKEG-----KKEVES 259
Query: 198 EEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKEREDGKEDE---------GGNEEE 248
+ ++ +TG D +E+GD +EG EK+R+ G+ + G +E+E
Sbjct: 260 KRKNLAKTG-VTSTSDSEEEGDDQEG--------EKKRKGGRNFQTAHRRNMLKGQHEKE 310
Query: 249 AGKEKEDLKEEEEGKEEDEIKEDDGKKEEPQSI 281
A K +++EE E ++ +D+GKK E + +
Sbjct: 311 AADRK---RKQEEQMETEQQNKDEGKKPEVKKV 340
Score = 39.3 bits (90), Expect = 0.004
Identities = 49/205 (23%), Positives = 90/205 (43%), Gaps = 22/205 (10%)
Query: 6 AAGQGDMRQEPKRRSARLSAMLVPVTPEVKPKRTSSSRKMKTKSDMMEENIDTSAQAVAE 65
A +++ PKR + + +P P +PK + ++SD++ E D S + E
Sbjct: 168 ATASVNLKVSPKRGRPAATEVKIP-KPRGRPKMVK--QPCPSESDIITEE-DKSKKKGQE 223
Query: 66 TKQEAVVEEDYNENAKNGEAKITEAPASE-KEIVEVKEENIEDATEKGGEKKEAVAAEVK 124
KQ + E K + E E K+ VE K +N+ K V +
Sbjct: 224 EKQPKKQPKKDEEGQKEEDKPRKEPDKKEGKKEVESKRKNLA---------KTGVTSTSD 274
Query: 125 NEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKG 184
+EEE +D+E + + KG + + G+ +K + D K K++ ++ E +
Sbjct: 275 SEEEG--DDQEGEKKRKGGRNFQTAHRRNMLKGQHEK----EAADRKRKQE-EQMETEQQ 327
Query: 185 NGEDGKEKGEDEKEEEDRKETGDGK 209
N ++GK K E +K E+ R+ + D +
Sbjct: 328 NKDEGK-KPEVKKVEKKRETSMDSR 351
Score = 36.6 bits (83), Expect = 0.025
Identities = 24/98 (24%), Positives = 51/98 (52%), Gaps = 12/98 (12%)
Query: 117 EAVAAEVKNEE--EDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKE 174
++V +V N+ E ++ +E ++ +++G+ G K EK E+ G + NG G DA++
Sbjct: 433 DSVITQVLNKSLAEQRQHEEANKTKDQGKKGPNKKLEK-EQTGSKTLNG---GSDAQD-- 486
Query: 175 DGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENE 212
G + NGE ++ ++ + +K + + +E E
Sbjct: 487 ----GNQPQHNGESNEDSKDNHEASTKKKPSSEERETE 520
Score = 28.5 bits (62), Expect = 6.9
Identities = 18/78 (23%), Positives = 37/78 (47%), Gaps = 5/78 (6%)
Query: 203 KETGDGKENEDGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEG 262
K + +++E+ + D +GK K+ EKE+ K GG++ + G + + E
Sbjct: 442 KSLAEQRQHEEANKTKD--QGKKGPNKKLEKEQTGSKTLNGGSDAQDGNQPQ---HNGES 496
Query: 263 KEEDEIKEDDGKKEEPQS 280
E+ + + K++P S
Sbjct: 497 NEDSKDNHEASTKKKPSS 514
Score = 28.1 bits (61), Expect = 9.0
Identities = 25/108 (23%), Positives = 43/108 (39%), Gaps = 19/108 (17%)
Query: 153 GEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENE 212
GE D + N+ + ++ E+ K +D G+ G K + EKE+ K G + +
Sbjct: 430 GEGDSVITQVLNKSLAEQRQHEEANKTKD---QGKKGPNK-KLEKEQTGSKTLNGGSDAQ 485
Query: 213 DGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEE 260
DG + + + ED N E + K+K +E E
Sbjct: 486 DGNQP---------------QHNGESNEDSKDNHEASTKKKPSSEERE 518
>gi|221316599 chromogranin B precursor [Homo sapiens]
Length = 677
Score = 71.2 bits (173), Expect = 9e-13
Identities = 61/267 (22%), Positives = 118/267 (44%), Gaps = 26/267 (9%)
Query: 29 PVTPE-----------VKPKRTSSSRKMKTKSDMMEENIDTSAQAVAETKQEAVV--EED 75
P+TPE VK K T+ + K + ++ + D S + ++ EA EED
Sbjct: 52 PITPECRQVLKTSRKDVKDKETTENENTKFEVRLLRDPADASEAHESSSRGEAGAPGEED 111
Query: 76 YNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEE 135
K K E +E + + ++ + + E+ + +E E++++ EE
Sbjct: 112 IQGPTKADTEKWAEGGGHSRERADEPQWSLYPSDSQVSEEVKTRHSEKSQREDEEE--EE 169
Query: 136 DQNEEKGEAGKEDKDEKGEEDGKEDKNG--NEKGEDA--KEKEDGKKGEDGKGNGEDGKE 191
+N +KGE G++ +EK E+ E +N NE+ + + K++E + E K
Sbjct: 170 GENYQKGERGEDSSEEKHLEEPGETQNAFLNERKQASAIKKEELVARSETHAAGHSQEKT 229
Query: 192 KGEDEKEEEDRKETGDGKENEDGKEKG------DKKEGKDVKVKEDEKEREDGKEDEGGN 245
++ +E +ETG +EN + KG + +EG++ E +K R + G +
Sbjct: 230 HSREKSSQESGEETG-SQENHPQESKGQPRSQEESEEGEEDATSEVDKRRTRPRHHHGRS 288
Query: 246 EEEAGKEKEDLKEEEEGKEEDEIKEDD 272
+ + L EE+G ++E +E +
Sbjct: 289 RPDRSSQGGSLPSEEKGHPQEESEESN 315
Score = 59.3 bits (142), Expect = 4e-09
Identities = 60/265 (22%), Positives = 110/265 (41%), Gaps = 24/265 (9%)
Query: 6 AAGQGDMRQEPKRRSARLSAMLVPVTPEVKPKRTSSSRKMKTKSDMMEENIDTSAQAVAE 65
A G G R+ L V+ EVK + + S++ + + + EN +
Sbjct: 124 AEGGGHSRERADEPQWSLYPSDSQVSEEVKTRHSEKSQR-EDEEEEEGENYQKGERGEDS 182
Query: 66 TKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKN 125
++++ + E +NA E K +A A +KE + + E T G +E + K+
Sbjct: 183 SEEKHLEEPGETQNAFLNERK--QASAIKKEELVARSE-----THAAGHSQEKTHSREKS 235
Query: 126 EEEDQKEDEEDQN---EEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGED- 181
+E +E +N E KG+ +++ E+GEED + +K G+ D
Sbjct: 236 SQESGEETGSQENHPQESKGQPRSQEESEEGEEDATSEV---DKRRTRPRHHHGRSRPDR 292
Query: 182 -GKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKEREDGKE 240
+G +EKG ++E E+ N G+K++ + E+E E G+E
Sbjct: 293 SSQGGSLPSEEKGHPQEESEE--------SNVSMASLGEKRDHHSTHYRASEEEPEYGEE 344
Query: 241 DEGGNEEEAGKEKEDLKEEEEGKEE 265
+G +A ++ E + G EE
Sbjct: 345 IKGYPGVQAPEDLEWERYRGRGSEE 369
Score = 36.6 bits (83), Expect = 0.025
Identities = 52/295 (17%), Positives = 114/295 (38%), Gaps = 42/295 (14%)
Query: 6 AAGQGDMRQEPKRRSARLSAMLVPVTPEVKPKRTSSSRKMKTKSDMMEENIDTSAQAVAE 65
AAG + + +S++ S E + + ++ K + EE+ + A +E
Sbjct: 221 AAGHSQEKTHSREKSSQESG-------EETGSQENHPQESKGQPRSQEESEEGEEDATSE 273
Query: 66 T-KQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVK 124
K+ + + + ++ P+ EK + + E + GEK++ + +
Sbjct: 274 VDKRRTRPRHHHGRSRPDRSSQGGSLPSEEKGHPQEESEESNVSMASLGEKRDHHSTHYR 333
Query: 125 NEEEDQKEDEE-------------------DQNEEKGEAGKEDKDEKGEEDGKE------ 159
EE+ + EE + E+ A + +E +E+ K
Sbjct: 334 ASEEEPEYGEEIKGYPGVQAPEDLEWERYRGRGSEEYRAPRPQSEESWDEEDKRNYPSLE 393
Query: 160 -DKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKG---EDEKEEEDRKETGDGKENEDGK 215
DK + GE+++E+ + G+ G G+ + D +EE+ G + E+
Sbjct: 394 LDKMAHGYGEESEEERGLEPGKGRHHRGRGGEPRAYFMSDTREEKRFLGEGHHRVQENQM 453
Query: 216 EKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKE 270
+K ++ + + D G+E G ++ G DL++ +E +EE ++
Sbjct: 454 DKA-RRHPQGAWKELDRNYLNYGEEGAPGKWQQQG----DLQDTKENREEARFQD 503
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 70.9 bits (172), Expect = 1e-12
Identities = 62/305 (20%), Positives = 153/305 (50%), Gaps = 33/305 (10%)
Query: 1 MPKRKAAGQGD-MRQEPKRRSARLSAMLVPVTPEVKPKRTSSSRKMKTKSDMMEENIDTS 59
+P+++ + D + +E + SA+L A + E +++ + K EE I
Sbjct: 246 LPQQQLQAEADHLGKELQSVSAKLQAQV-----EENELWNRLNQQQEEKMWRQEEKIQER 300
Query: 60 AQAVAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAV 119
+ + E +++ +E+ + + E ++E++ KEE I + EK E+++
Sbjct: 301 EEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIR 360
Query: 120 AAEVKNEEEDQKEDEEDQNEEKGEAGKEDK----------------DEKGEEDGKEDKNG 163
E K +EE++ ++E + E++ + ++++ E+ E+ G++++
Sbjct: 361 EQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKM 420
Query: 164 NEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEK---EEEDRKETGDGKENEDGK---EK 217
E+ E+ +E+E+ + ++ K ++ K + ++EK +EE +E + ++GK ++
Sbjct: 421 WEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQE 480
Query: 218 GDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGK---EEDEIKEDDGK 274
+E ++ +++EK RE K+ +EE +E+E++ +E+E K +E+++ E + K
Sbjct: 481 AKMQEQEEKMRRQEEKIREQEKKIR--EQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEK 538
Query: 275 KEEPQ 279
+E +
Sbjct: 539 MQEQE 543
Score = 67.0 bits (162), Expect = 2e-11
Identities = 54/237 (22%), Positives = 123/237 (51%), Gaps = 18/237 (7%)
Query: 44 KMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEV--K 101
KM+ + +MM E + + + ++ + E E + E KI E +++ ++ +
Sbjct: 331 KMRRQEEMMWEKEEKIRELEEKMHEQEKIREQ--EEKRQEEEKIREQEKRQEQEAKMWRQ 388
Query: 102 EENIEDATEKGGEKKEAVAAEVKN---EEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGK 158
EE I + EK E++E + + + +EE E EE+ E+ E+K + EE +
Sbjct: 389 EEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQ------EEKMRRQEEKIR 442
Query: 159 E-DKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEK 217
E +K E+ E +E+E+ + ++ K ++GK ++ K +E ++ ++ E +E+
Sbjct: 443 EQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKM--RRQEEKIREQ 500
Query: 218 GDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEE--GKEEDEIKEDD 272
K ++ K++E E+ ++ +E EE+ +++E ++E+EE ++E++++E +
Sbjct: 501 EKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQE 557
Score = 65.9 bits (159), Expect = 4e-11
Identities = 50/228 (21%), Positives = 117/228 (51%), Gaps = 9/228 (3%)
Query: 44 KMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEE 103
K++ + M E Q ++E + E++ + + + E ++E + +EE
Sbjct: 345 KIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEE 404
Query: 104 NIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNG 163
+++ EK GE++E + + EEE Q+++E+ + +E+ +E K + EE +E +
Sbjct: 405 MMQEQEEKMGEQEEKMWEQ---EEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEM 461
Query: 164 NEKGEDAKEKEDGKKGE-DGKGNGEDGKEKGEDEKEEEDRKETGDGKE-----NEDGKEK 217
++ E+ +++GK E + K ++ K + ++EK E K+ + +E E +E+
Sbjct: 462 MQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQ 521
Query: 218 GDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEE 265
+K ++ K+ E E++ ++ +E EE+ +++ L+++EE +E
Sbjct: 522 EEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQE 569
Score = 64.7 bits (156), Expect = 9e-11
Identities = 67/287 (23%), Positives = 139/287 (48%), Gaps = 30/287 (10%)
Query: 14 QEPKRRSARLSAMLVPVTPEVKP--------KRTSSSRKMKTKSDMMEENIDTSAQAV-- 63
+E K ++A+L L V E KR K+ ++ D + +
Sbjct: 205 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 264
Query: 64 AETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEV 123
K +A VEE+ N N + + E ++E ++ +EE I++ EK E++E +
Sbjct: 265 VSAKLQAQVEENELWNRLNQQQE--EKMWRQEEKIQEREEKIQEQEEKIREQEEKMR--- 319
Query: 124 KNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGK 183
+ EE +++E+ + +E+ KE+K + EE E + E+ E K +E+ K E K
Sbjct: 320 RQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEE--KRQEEEKIREQEK 377
Query: 184 GNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGK-DVKVKEDEKEREDGKEDE 242
++ K ++EK E ++ +E E+ ++ ++K G+ + K+ E E+E ++ +E
Sbjct: 378 RQEQEAKMWRQEEKIREQEEKI---REQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKM 434
Query: 243 GGNEEEAGKEKEDLKEEEEG---------KEEDEIKEDDGKKEEPQS 280
EE+ ++++ ++E+EE ++E+++ E +GK E ++
Sbjct: 435 RRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEA 481
Score = 57.0 bits (136), Expect = 2e-08
Identities = 54/284 (19%), Positives = 141/284 (49%), Gaps = 45/284 (15%)
Query: 40 SSSRKMKTKSDMMEENIDTSAQAVA-ETKQEAVVEEDYNENAKNGEAKITEAPASEKEI- 97
S+ K K+D E + A++ E + + +E+ E + K+ + + EI
Sbjct: 170 SAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQ 229
Query: 98 VEVKE--------------ENIEDATEKGGEKKEAVAAEVK------------NEEEDQK 131
+ VKE + ++ + G++ ++V+A+++ N+++++K
Sbjct: 230 LNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEK 289
Query: 132 ---------EDEEDQNEEKGEAGKEDKDEKGEED---GKEDKNGNEKGEDAKEKEDGKKG 179
E EE E++ + ++++ + +E+ KE+K ++ E EKE+ +
Sbjct: 290 MWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQE-EMMWEKEEKIRE 348
Query: 180 EDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGK--EKGDKKEGKDVKVKEDEKERED 237
+ K + ++ + E++++EE++ + ++ ++ K + +K ++ K++E E+ ++
Sbjct: 349 LEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQE 408
Query: 238 GKEDEGGNEEEAGKEKEDLKEEEE--GKEEDEIKEDDGKKEEPQ 279
+E G EE+ +++E+++E+EE ++E++I+E + K E +
Sbjct: 409 QEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQE 452
Score = 48.9 bits (115), Expect = 5e-06
Identities = 40/211 (18%), Positives = 108/211 (51%), Gaps = 16/211 (7%)
Query: 33 EVKPKRTSSSRKMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEA--KITEA 90
E K + ++ + K EE I + + E QE +++E + + E + E
Sbjct: 369 EEKIREQEKRQEQEAKMWRQEEKIREQEEKIRE--QEEMMQEQEEKMGEQEEKMWEQEEE 426
Query: 91 PASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDK- 149
++E + +EE I + +K E++E +++ +EE +E EE E++G+ +++
Sbjct: 427 MQEQEEKMRRQEEKIREQEKKIREQEE----KIREQEEMMQEQEEKMGEQEGKMCEQEAK 482
Query: 150 -DEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEK--EEEDRKETG 206
E+ E+ ++++ E+ + +E+E+ + ++ ++ K ++EK E+E++ +
Sbjct: 483 MQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQ-- 540
Query: 207 DGKENEDGKEKGDKKEGKDVKVKEDEKERED 237
++ E + + +K ++V++++ E++ ++
Sbjct: 541 --EQEEKMRRQEEKMREQEVRLRQQEEKMQE 569
>gi|24415404 MDN1, midasin homolog [Homo sapiens]
Length = 5596
Score = 70.9 bits (172), Expect = 1e-12
Identities = 63/250 (25%), Positives = 110/250 (44%), Gaps = 25/250 (10%)
Query: 31 TPEVKPKRTSSSRKMKTKSDMMEE---NIDTSAQAVAETKQEAVVEEDYNENAKNGEAKI 87
T E P ++ K D ++ N D S Q E K+EA ++ GE KI
Sbjct: 4795 TEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADD-----GGQGEDKI 4849
Query: 88 TEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQN---EEKGEA 144
E ++ ++ + + G +++ E + +D D ED+N + E
Sbjct: 4850 NEQ-------IDERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDNEE 4902
Query: 145 GKEDK----DEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEE 200
G+E+ EK EE G E + E D E + ++ E+G ED K +GE+E +
Sbjct: 4903 GEEENPLEIKEKPEEAGHEAEERGETETDQNESQSPQEPEEGP--SEDDKAEGEEEMDTG 4960
Query: 201 DRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEE 260
+ GD ++ + + ++ ++ + DE+ E+G D+G +E +E+ED EE
Sbjct: 4961 ADDQDGDAAQHPEEHSEEQQQSVEEKDKEADEEGGENGPADQGFQPQEE-EEREDSDTEE 5019
Query: 261 EGKEEDEIKE 270
+ E E KE
Sbjct: 5020 QVPEALERKE 5029
Score = 69.3 bits (168), Expect = 4e-12
Identities = 59/233 (25%), Positives = 110/233 (47%), Gaps = 18/233 (7%)
Query: 39 TSSSRKMKTKSDMMEENIDTSAQAVAETKQ---EAVVEEDYNENAKNGEAKITEAPASEK 95
+ +S K K++ D EE + A + + E + E DY+EN + E E
Sbjct: 4818 SGNSNKDKSQQDKKEEKEEAEADDGGQGEDKINEQIDERDYDENEVDPYHGNQEK-VPEP 4876
Query: 96 EIVEVKEE-NIEDATEKGGEKKEAVAAEVKNEEEDQKEDEE--DQNEEKGEAGKEDKDEK 152
E +++ ++ N++ + GGE + E +N E +++ EE + EE+GE + + +
Sbjct: 4877 EALDLPDDLNLDSEDKNGGEDTDNEEGEEENPLEIKEKPEEAGHEAEERGETETDQNESQ 4936
Query: 153 GEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRK-ETGDGKEN 211
++ +E + ++K E +E + G +DG D + E+ EE+ + E D + +
Sbjct: 4937 SPQEPEEGPSEDDKAEGEEEMDTGADDQDG-----DAAQHPEEHSEEQQQSVEEKDKEAD 4991
Query: 212 EDGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKE 264
E+G E G +G ++E+ERED +E EA + KE + G E
Sbjct: 4992 EEGGENGPADQGFQ---PQEEEEREDSDTEE--QVPEALERKEHASCGQTGVE 5039
Score = 67.8 bits (164), Expect = 1e-11
Identities = 50/187 (26%), Positives = 98/187 (52%), Gaps = 14/187 (7%)
Query: 103 ENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKN 162
E ++D +++ G +++ K +E+D KED + +++ KGE + E + DGK
Sbjct: 4684 EGMKDVSDQIGNEEQVEDTFQKGQEKD-KEDPDSKSDIKGEDNAIEMSE--DFDGKMHDG 4740
Query: 163 GNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKE 222
E+ E+ EK D + G+ K G+ E E ++ D + GD E ED +E+ +K E
Sbjct: 4741 ELEEQEEDDEKSDSEGGDLDKHMGDLNGE----EADKLDERLWGDDDEEEDEEEEDNKTE 4796
Query: 223 GKDVKVKEDEKE---REDGKEDEGGNEEEAGKEKEDLKEEEE----GKEEDEIKEDDGKK 275
+ E++ E ++D + N++++ ++K++ KEE E G+ ED+I E ++
Sbjct: 4797 ETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGEDKINEQIDER 4856
Query: 276 EEPQSIV 282
+ ++ V
Sbjct: 4857 DYDENEV 4863
Score = 67.8 bits (164), Expect = 1e-11
Identities = 53/193 (27%), Positives = 101/193 (52%), Gaps = 22/193 (11%)
Query: 102 EENIEDATEKGGEKKEA---VAAEVKNEEE--DQKEDEEDQNEEKGEAGKEDKDEKGEED 156
EE +ED +KG EK + +++K E+ + ED + + + +E+ DEK + +
Sbjct: 4696 EEQVEDTFQKGQEKDKEDPDSKSDIKGEDNAIEMSEDFDGKMHDGELEEQEEDDEKSDSE 4755
Query: 157 GKE-DKN-GNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDG 214
G + DK+ G+ GE+A + ++ G+D D +E ++E+E+ +ETG G + ED
Sbjct: 4756 GGDLDKHMGDLNGEEADKLDERLWGDD------DEEE--DEEEEDNKTEETGPGMDEEDS 4807
Query: 215 K--EKGDK----KEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEI 268
+ K D KD ++ ++E+E+ + D+GG E+ E+ D ++ +E E D
Sbjct: 4808 ELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGEDKINEQIDERDYDE-NEVDPY 4866
Query: 269 KEDDGKKEEPQSI 281
+ K EP+++
Sbjct: 4867 HGNQEKVPEPEAL 4879
Score = 67.4 bits (163), Expect = 1e-11
Identities = 66/245 (26%), Positives = 108/245 (44%), Gaps = 40/245 (16%)
Query: 73 EEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKE 132
EE + + G+ K E P S+ +I + ++ IE + + G+ + E EE+D+K
Sbjct: 4696 EEQVEDTFQKGQEKDKEDPDSKSDI-KGEDNAIEMSEDFDGKMHDGELEE--QEEDDEKS 4752
Query: 133 DEE--DQNEEKGEAGKEDKDEKGEE---DGKEDKNGNEKGEDAKEKEDGKKGEDGK---- 183
D E D ++ G+ E+ D+ E D E+++ E+ +E G ED +
Sbjct: 4753 DSEGGDLDKHMGDLNGEEADKLDERLWGDDDEEEDEEEEDNKTEETGPGMDEEDSELVAK 4812
Query: 184 ----GNGEDGKEKG-EDEKEEEDRKETGDGKENED-----------GKEKGDKKEGKDVK 227
+G K+K +D+KEE++ E DG + ED + + D G K
Sbjct: 4813 DDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGEDKINEQIDERDYDENEVDPYHGNQEK 4872
Query: 228 VKEDE-----KEREDGKEDEGGNEE---EAGKEKEDL----KEEEEGKEEDEIKEDDGKK 275
V E E + ED+ G E+ E G+E+ L K EE G E +E E + +
Sbjct: 4873 VPEPEALDLPDDLNLDSEDKNGGEDTDNEEGEEENPLEIKEKPEEAGHEAEERGETETDQ 4932
Query: 276 EEPQS 280
E QS
Sbjct: 4933 NESQS 4937
Score = 67.4 bits (163), Expect = 1e-11
Identities = 64/258 (24%), Positives = 118/258 (45%), Gaps = 53/258 (20%)
Query: 53 EENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKG 112
+ + + + E E V ++D N +G + +K + KEE E + G
Sbjct: 4792 DNKTEETGPGMDEEDSELVAKDD---NLDSGNSN------KDKSQQDKKEEKEEAEADDG 4842
Query: 113 GEKKEAVAAEVKNEEEDQKE-DEEDQNEEK-GEAGKEDKDEKGEEDGKEDKNG-----NE 165
G+ ++ + ++ + D+ E D N+EK E D + D EDKNG NE
Sbjct: 4843 GQGEDKINEQIDERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDS-EDKNGGEDTDNE 4901
Query: 166 KGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKD 225
+GE+ E +K E+ G + +E+GE E D+ E+ +E E+G + DK EG
Sbjct: 4902 EGEEENPLEIKEKPEEA---GHEAEERGETET---DQNESQSPQEPEEGPSEDDKAEG-- 4953
Query: 226 VKVKEDEKEREDGKEDEGGN----------EEEAGKEKEDLKEEEEG------------K 263
E+E + G +D+ G+ E++ E++D + +EEG +
Sbjct: 4954 ------EEEMDTGADDQDGDAAQHPEEHSEEQQQSVEEKDKEADEEGGENGPADQGFQPQ 5007
Query: 264 EEDEIKEDDGKKEEPQSI 281
EE+E ++ D +++ P+++
Sbjct: 5008 EEEEREDSDTEEQVPEAL 5025
Score = 62.0 bits (149), Expect = 6e-10
Identities = 52/213 (24%), Positives = 97/213 (45%), Gaps = 28/213 (13%)
Query: 93 SEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEK 152
S +++ V + + +KG + + E + D E +GE K+ D+
Sbjct: 4634 STAKLLSVLAQVFTELAQKGFCLPKEFMEDSAGEGATEFHDYEGGGIGEGEGMKDVSDQI 4693
Query: 153 GEEDGKED--KNGNEKGEDAKEKEDGKKGEDGK--------GNGEDGKEKGEDEKEEEDR 202
G E+ ED + G EK ++ + + KGED G DG+ + ++E +E+
Sbjct: 4694 GNEEQVEDTFQKGQEKDKEDPDSKSDIKGEDNAIEMSEDFDGKMHDGELEEQEEDDEKSD 4753
Query: 203 KETGD-----GKENEDGKEKGDKKEGKDVKVKEDEKEREDGKEDEG-GNEEE-------- 248
E GD G N + +K D++ D +EDE+E ++ E+ G G +EE
Sbjct: 4754 SEGGDLDKHMGDLNGEEADKLDERLWGDDDEEEDEEEEDNKTEETGPGMDEEDSELVAKD 4813
Query: 249 ----AGKEKEDLKEEEEGKEEDEIKEDDGKKEE 277
+G +D ++++ +E++E + DDG + E
Sbjct: 4814 DNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGE 4846
Score = 55.8 bits (133), Expect = 4e-08
Identities = 59/235 (25%), Positives = 107/235 (45%), Gaps = 22/235 (9%)
Query: 61 QAVAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVA 120
+A E ++ E D NE+ E + E P SE + E +EE A ++ G+ A
Sbjct: 4917 EAGHEAEERGETETDQNESQSPQEPE--EGP-SEDDKAEGEEEMDTGADDQDGDA--AQH 4971
Query: 121 AEVKNEEEDQKEDEEDQ--NEEKGEAGKEDKD-EKGEEDGKEDKNGNEKGEDAKEKED-- 175
E +EE+ Q +E+D+ +EE GE G D+ + EE+ +ED + E+ +A E+++
Sbjct: 4972 PEEHSEEQQQSVEEKDKEADEEGGENGPADQGFQPQEEEEREDSDTEEQVPEALERKEHA 5031
Query: 176 --GKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKK------EGKDVK 227
G+ G + N + + G ++E+ ++E G G + + E + K +
Sbjct: 5032 SCGQTGVENMQNTQAMELAGAAPEKEQGKEEHGSGAADANQAEGHESNFIAQLASQKHTR 5091
Query: 228 VKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDDGKKEEPQSIV 282
+R+ G+ D NE G E + + + D E G ++PQ+ V
Sbjct: 5092 KNTQSFKRKPGQAD---NERSMGDHNERVHKRLRTVDTDSHAE-QGPAQQPQAQV 5142
Score = 53.1 bits (126), Expect = 3e-07
Identities = 58/280 (20%), Positives = 111/280 (39%), Gaps = 28/280 (10%)
Query: 29 PVTPEVKPKRTS--SSRKMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEAK 86
P+ + KP+ + + +T++D E + +A EE+ + A + +
Sbjct: 4908 PLEIKEKPEEAGHEAEERGETETDQNESQSPQEPEEGPSEDDKAEGEEEMDTGADDQDGD 4967
Query: 87 ITEAPASEKEIVEVK-EENIEDATEKGGEKKEAVAA-EVKNEEEDQKEDEEDQNEEKGEA 144
+ P E + EE ++A E+GGE A + + EEE + D E+Q E E
Sbjct: 4968 AAQHPEEHSEEQQQSVEEKDKEADEEGGENGPADQGFQPQEEEEREDSDTEEQVPEALER 5027
Query: 145 GKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDE-------K 197
+ + + ++ E A EKE GK+ E G G + + +G +
Sbjct: 5028 KEHASCGQTGVENMQNTQAMELAGAAPEKEQGKE-EHGSGAADANQAEGHESNFIAQLAS 5086
Query: 198 EEEDRKETGDGK------ENEDGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGK 251
++ RK T K +NE +++ K ++ + + E G + + E
Sbjct: 5087 QKHTRKNTQSFKRKPGQADNERSMGDHNERVHKRLRTVDTDSHAEQGPAQQPQAQVEDAD 5146
Query: 252 EKEDLKEEEE----------GKEEDEIKEDDGKKEEPQSI 281
E +K+ + KE+ + +D GK +E + I
Sbjct: 5147 AFEHIKQGSDAYDAQTYDVASKEQQQSAKDSGKDQEEEEI 5186
Score = 45.4 bits (106), Expect = 5e-05
Identities = 66/301 (21%), Positives = 119/301 (39%), Gaps = 50/301 (16%)
Query: 29 PVTPEVKPK---RTSSSRKMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEA 85
P PE P + +M T +D + + + +E +Q++V E+D + + GE
Sbjct: 4938 PQEPEEGPSEDDKAEGEEEMDTGADDQDGDAAQHPEEHSEEQQQSVEEKDKEADEEGGEN 4997
Query: 86 KITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAE---VKNEEEDQKED------EED 136
+ +E E ++ + E+ + E+KE + V+N + Q + E++
Sbjct: 4998 GPADQGFQPQEEEEREDSDTEEQVPEALERKEHASCGQTGVENMQNTQAMELAGAAPEKE 5057
Query: 137 QNEEKGEAGKEDKDE-KGEEDGKEDKNGNEK-------------GEDAKEKEDGKKGE-- 180
Q +E+ +G D ++ +G E + ++K G+ E+ G E
Sbjct: 5058 QGKEEHGSGAADANQAEGHESNFIAQLASQKHTRKNTQSFKRKPGQADNERSMGDHNERV 5117
Query: 181 -------DGKGNGEDG-----KEKGEDEKEEEDRKETGDGKENE--DGKEKGDKKEGKDV 226
D + E G + + ED E K+ D + + D K ++ KD
Sbjct: 5118 HKRLRTVDTDSHAEQGPAQQPQAQVEDADAFEHIKQGSDAYDAQTYDVASKEQQQSAKDS 5177
Query: 227 KVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEE--------EGKEEDEIKEDDGKKEEP 278
++E+E ED D EE + E LK EE G +E E++ K EE
Sbjct: 5178 GKDQEEEEIEDTLMDTEEQEEFKAADVEQLKPEEIKSGTTAPLGFDEMEVEIQTVKTEED 5237
Query: 279 Q 279
Q
Sbjct: 5238 Q 5238
Score = 38.9 bits (89), Expect = 0.005
Identities = 57/292 (19%), Positives = 112/292 (38%), Gaps = 26/292 (8%)
Query: 10 GDMRQEPKRRSARLSAMLVPVTPEVKPK---RTSSSRKMKTKSDMMEENIDTSAQA--VA 64
GD Q P+ S + E + + + + + + E+ DT Q
Sbjct: 4966 GDAAQHPEEHSEEQQQSVEEKDKEADEEGGENGPADQGFQPQEEEEREDSDTEEQVPEAL 5025
Query: 65 ETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEEN---IEDATEKGGEKKEAVA- 120
E K+ A + EN +N +A A EKE + KEE+ DA + G + +A
Sbjct: 5026 ERKEHASCGQTGVENMQNTQAMELAGAAPEKE--QGKEEHGSGAADANQAEGHESNFIAQ 5083
Query: 121 -AEVKNEEED-----QKEDEEDQNEEKGEAGKE--------DKDEKGEEDGKEDKNGNEK 166
A K+ ++ +K + D G+ + D D E+ + +
Sbjct: 5084 LASQKHTRKNTQSFKRKPGQADNERSMGDHNERVHKRLRTVDTDSHAEQGPAQQPQAQVE 5143
Query: 167 GEDAKEK-EDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKD 225
DA E + G D + KE+ + K+ +E + ++ E+ ++ + D
Sbjct: 5144 DADAFEHIKQGSDAYDAQTYDVASKEQQQSAKDSGKDQEEEEIEDTLMDTEEQEEFKAAD 5203
Query: 226 VKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDDGKKEE 277
V+ + E+ + G +E E + +E+++ + + KE + +K E
Sbjct: 5204 VEQLKPEEIKSGTTAPLGFDEMEVEIQTVKTEEDQDPRTDKAHKETENEKPE 5255
Score = 34.3 bits (77), Expect = 0.13
Identities = 40/179 (22%), Positives = 72/179 (40%), Gaps = 25/179 (13%)
Query: 35 KPKRTSSSRKMKTKSDMMEENIDT------SAQAVAETKQEAVVEEDYNENAKNGEAKIT 88
KP + + R M ++ + + + T + Q A+ Q V + D E+ K G
Sbjct: 5100 KPGQADNERSMGDHNERVHKRLRTVDTDSHAEQGPAQQPQAQVEDADAFEHIKQG----- 5154
Query: 89 EAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKED 148
+ A + + +V + + + + G K++EE++ ED EE+ E D
Sbjct: 5155 -SDAYDAQTYDVASKEQQQSAKDSG----------KDQEEEEIEDTLMDTEEQEEFKAAD 5203
Query: 149 KDEKGEEDGKEDKNGNEKGEDAKEKE--DGKKGEDGKGNGEDGKEKGEDEKEEEDRKET 205
++ E+ K G D E E K ED + ++ E+EK E R+ T
Sbjct: 5204 VEQLKPEEIKSGTTA-PLGFDEMEVEIQTVKTEEDQDPRTDKAHKETENEKPERSREST 5261
Score = 32.7 bits (73), Expect = 0.37
Identities = 44/202 (21%), Positives = 77/202 (38%), Gaps = 36/202 (17%)
Query: 75 DYNENAKNGEAKITEAPASEKEIVEVKEENIEDAT-----EKGGEKKEAVAAEVKNEEED 129
D+NE + +E+ + + +EDA ++G + +A +V ++E+
Sbjct: 5112 DHNERVHKRLRTVDTDSHAEQGPAQQPQAQVEDADAFEHIKQGSDAYDAQTYDVASKEQQ 5171
Query: 130 Q--KEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGE 187
Q K+ +DQ EE+ E D +E+ E + + + E+ K G +
Sbjct: 5172 QSAKDSGKDQEEEEIEDTLMDTEEQEEFKAAD--------VEQLKPEEIKSGTTAPLGFD 5223
Query: 188 DGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEG-------------------KDVKV 228
+ + + + K EED+ D E EK ++ KDV
Sbjct: 5224 EMEVEIQTVKTEEDQDPRTDKAHKETENEKPERSRESTIHTAHQFLMDTIFQPFLKDVNE 5283
Query: 229 KEDEKER--EDGKEDEGGNEEE 248
E ER E + E GN EE
Sbjct: 5284 LRQELERQLEMWQPRESGNPEE 5305
Score = 28.1 bits (61), Expect = 9.0
Identities = 19/81 (23%), Positives = 34/81 (41%), Gaps = 12/81 (14%)
Query: 95 KEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKD---- 150
+EI+ +E A EK ++ +N E+EE++ E + + +KD
Sbjct: 3529 QEIISEWDEQERIAQEKAEQESGLYRYRSRNSRTALSEEEEEEREFRKQFPLHEKDFADI 3588
Query: 151 --------EKGEEDGKEDKNG 163
KG DG+E++ G
Sbjct: 3589 LVQPTLEENKGTSDGQEEEAG 3609
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.289 0.119 0.299
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,387,265
Number of Sequences: 37866
Number of extensions: 929598
Number of successful extensions: 57481
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1306
Number of HSP's successfully gapped in prelim test: 1011
Number of HSP's that attempted gapping in prelim test: 5163
Number of HSP's gapped (non-prelim): 16812
length of query: 282
length of database: 18,247,518
effective HSP length: 101
effective length of query: 181
effective length of database: 14,423,052
effective search space: 2610572412
effective search space used: 2610572412
T: 11
A: 40
X1: 17 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 45 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.