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Search of human proteins with 13449281
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13449281 apolipoprotein L6 [Homo sapiens]
(343 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13449281 apolipoprotein L6 [Homo sapiens] 676 0.0
gi|13470094 apolipoprotein L5 [Homo sapiens] 188 5e-48
gi|22035646 apolipoprotein L3 isoform 1 [Homo sapiens] 167 1e-41
gi|13562090 apolipoprotein L2 [Homo sapiens] 150 2e-36
gi|22035653 apolipoprotein L2 [Homo sapiens] 150 2e-36
gi|211938442 apolipoprotein L1 isoform c precursor [Homo sapiens] 145 7e-35
gi|211938440 apolipoprotein L1 isoform a precursor [Homo sapiens] 145 7e-35
gi|21735616 apolipoprotein L1 isoform b precursor [Homo sapiens] 145 7e-35
gi|21735614 apolipoprotein L1 isoform a precursor [Homo sapiens] 145 7e-35
gi|22035650 apolipoprotein L3 isoform 3 [Homo sapiens] 118 7e-27
gi|22035648 apolipoprotein L3 isoform 3 [Homo sapiens] 118 7e-27
gi|19923626 apolipoprotein L4 isoform 1 [Homo sapiens] 104 1e-22
gi|22035657 apolipoprotein L4 isoform 2 precursor [Homo sapiens] 104 1e-22
gi|194353995 apolipoprotein L domain containing 1 isoform 1 [Hom... 58 1e-08
gi|194353993 apolipoprotein L domain containing 1 isoform 2 [Hom... 58 1e-08
gi|24429572 TBP-associated factor RNA polymerase 1-like [Homo sa... 32 0.83
gi|7705415 hook homolog 1 [Homo sapiens] 32 1.1
gi|31982906 cingulin-like 1 [Homo sapiens] 32 1.1
gi|221219020 NYD-SP11 protein [Homo sapiens] 31 1.4
gi|157738667 FYVE and coiled-coil domain containing 1 [Homo sapi... 31 1.4
gi|46852174 kinesin family member 3A [Homo sapiens] 31 1.8
gi|12669915 E2F transcription factor 4 [Homo sapiens] 31 1.8
gi|38348729 hypothetical protein LOC203238 [Homo sapiens] 31 1.8
gi|29171682 interleukin 9 receptor precursor [Homo sapiens] 30 2.4
gi|19923312 v-myc myelocytomatosis viral related oncogene, neuro... 30 2.4
gi|4506671 ribosomal protein P2 [Homo sapiens] 30 2.4
gi|35493713 vacuolar protein sorting 13B isoform 5 [Homo sapiens] 30 3.1
gi|35493701 vacuolar protein sorting 13B isoform 1 [Homo sapiens] 30 3.1
gi|148762940 DVL-binding protein DAPLE [Homo sapiens] 30 3.1
gi|62865871 coiled-coil domain containing 132 isoform a [Homo sa... 30 3.1
>gi|13449281 apolipoprotein L6 [Homo sapiens]
Length = 343
Score = 676 bits (1744), Expect = 0.0
Identities = 343/343 (100%), Positives = 343/343 (100%)
Query: 1 MDNQAERESEAGVGLQRDEDDAPLCEDVELQDGDLSPEEKIFLREFPRLKEDLKGNIDKL 60
MDNQAERESEAGVGLQRDEDDAPLCEDVELQDGDLSPEEKIFLREFPRLKEDLKGNIDKL
Sbjct: 1 MDNQAERESEAGVGLQRDEDDAPLCEDVELQDGDLSPEEKIFLREFPRLKEDLKGNIDKL 60
Query: 61 RALADDIDKTHKKFTKANMVATSTAVISGVMSLLGLALAPATGGGSLLLSTAGQGLATAA 120
RALADDIDKTHKKFTKANMVATSTAVISGVMSLLGLALAPATGGGSLLLSTAGQGLATAA
Sbjct: 61 RALADDIDKTHKKFTKANMVATSTAVISGVMSLLGLALAPATGGGSLLLSTAGQGLATAA 120
Query: 121 GVTSIVSGTLERSKNKEAQARAEDILPTYDQEDREDEEEKADYVTAAGKIIYNLRNTLKY 180
GVTSIVSGTLERSKNKEAQARAEDILPTYDQEDREDEEEKADYVTAAGKIIYNLRNTLKY
Sbjct: 121 GVTSIVSGTLERSKNKEAQARAEDILPTYDQEDREDEEEKADYVTAAGKIIYNLRNTLKY 180
Query: 181 AKKNVRAFWKLRANPRLANATKRLLTTGQVSSRSRVQVQKAFAGTTLAMTKNARVLGGVM 240
AKKNVRAFWKLRANPRLANATKRLLTTGQVSSRSRVQVQKAFAGTTLAMTKNARVLGGVM
Sbjct: 181 AKKNVRAFWKLRANPRLANATKRLLTTGQVSSRSRVQVQKAFAGTTLAMTKNARVLGGVM 240
Query: 241 SAFSLGYDLATLSKEWKHLKEGARTKFAEELRAKALELERKLTELTQLYKSLQQKVRSRA 300
SAFSLGYDLATLSKEWKHLKEGARTKFAEELRAKALELERKLTELTQLYKSLQQKVRSRA
Sbjct: 241 SAFSLGYDLATLSKEWKHLKEGARTKFAEELRAKALELERKLTELTQLYKSLQQKVRSRA 300
Query: 301 RGVGKDLTGTCETEAYWKELREHVWMWLWLCVCLCVCVYVQFT 343
RGVGKDLTGTCETEAYWKELREHVWMWLWLCVCLCVCVYVQFT
Sbjct: 301 RGVGKDLTGTCETEAYWKELREHVWMWLWLCVCLCVCVYVQFT 343
>gi|13470094 apolipoprotein L5 [Homo sapiens]
Length = 433
Score = 188 bits (478), Expect = 5e-48
Identities = 112/284 (39%), Positives = 165/284 (58%), Gaps = 7/284 (2%)
Query: 25 CEDVELQDGDLSPEEKIFLREFPRLKEDLKGNIDKLRALADDIDKTHKKFTKANMVATST 84
C+ + DG+LS EEK+FL FP K +L+ NI +L LAD +D TH+ TK ++VA+S+
Sbjct: 85 CDKDSMPDGNLSEEEKLFLSYFPLHKFELEQNIKELNTLADQVDTTHELLTKTSLVASSS 144
Query: 85 AVISGVMSLLGLALAPATGGGSLLLSTAGQGLATAAGVTSIVSGTLERSKNKEAQARAED 144
+SGVM++LGLALAP T GGSL+LS G GL AA +T+IV+ LE N A+ +A
Sbjct: 145 GAVSGVMNILGLALAPVTAGGSLMLSATGTGLGAAAAITNIVTNVLENRSNSAARDKASR 204
Query: 145 ILPTYDQEDREDEEEKADYVTAAGKIIYNLRNTLKYAKKNVRAFWKLRANPRLANATKRL 204
+ P + ++ + AAG + ++ K++ A+ ++N K
Sbjct: 205 LGPLTTSHEAFGGINWSE-IEAAGFCVNKCVKAIQ-GIKDLHAYQMAKSNSGFMAMVKNF 262
Query: 205 LTTGQVSSRSRVQVQKAFAGTTLAMTKNARVLGGVMSAFSLGYDLATLSKEWKHLKEGAR 264
+ + + VQ+AF GTTLAMT A V+G + F L D+++ + WKHL++GAR
Sbjct: 263 VAKRHIPFWTARGVQRAFEGTTLAMTNGAWVMGAAGAGFLLMKDMSSFLQSWKHLEDGAR 322
Query: 265 TKFAEELRAKALELERKLTELTQLYKSLQQKV-----RSRARGV 303
T+ AEELRA A +LE++L LTQ ++ L QK SR R V
Sbjct: 323 TETAEELRALAKKLEQELDRLTQHHRHLPQKASQTCSSSRGRAV 366
>gi|22035646 apolipoprotein L3 isoform 1 [Homo sapiens]
Length = 402
Score = 167 bits (424), Expect = 1e-41
Identities = 111/302 (36%), Positives = 160/302 (52%), Gaps = 18/302 (5%)
Query: 2 DNQAERESEAGVGLQRDEDDA-----------PLCEDVELQDGDLSPEEKIFLREFPRLK 50
+N+A + L RDE DA ED +Q D E FL+EFP++K
Sbjct: 102 NNEAWKRFVTAAELPRDEADALYEALKKLRTYAAIEDEYVQQKDEQFREW-FLKEFPQVK 160
Query: 51 EDLKGNIDKLRALADDIDKTHKKFTKANMVATSTAVISGVMSLLGLALAPATGGGSLLLS 110
++ +I+KLRALA+ I++ H+ T +N+V++ST SG+MSL GL LAP T G SL L+
Sbjct: 161 RKIQESIEKLRALANGIEEVHRGCTISNVVSSSTGAASGIMSLAGLVLAPFTAGTSLALT 220
Query: 111 TAGQGLATAAGVTSIVSGTLERSKNKEAQARAEDILPTYDQEDREDEEEKADYVTAAGKI 170
AG GL A+ VT I + +E S A+A A + T + +E D +
Sbjct: 221 AAGVGLGAASAVTGITTSIVEHSYTSSAEAEASRLTATSIDRLKVFKEVMRDITPNLLSL 280
Query: 171 IYNLRNTLKYAKKNVRAFWKLRANPRLANATKRLLTTGQVSSRSRVQVQKAFAGTTLAMT 230
+ N + +RA + RA RL +TT ++S+ S Q ++ AGTT A++
Sbjct: 281 LNNYYEATQTIGSEIRAIRQARARARLP------VTTWRISAGSGGQAERTIAGTTRAVS 334
Query: 231 KNARVLGGVMSAFSLGYDLATLSKEWKHLKEGARTKFAEELRAKALELERKLTELTQLYK 290
+ AR+L S L D+ L E KHL EGA++ AEELR +A ELE L ELTQ+Y+
Sbjct: 335 RGARILSATTSGIFLALDVVNLVYESKHLHEGAKSASAEELRRQAQELEENLMELTQIYQ 394
Query: 291 SL 292
L
Sbjct: 395 RL 396
>gi|13562090 apolipoprotein L2 [Homo sapiens]
Length = 337
Score = 150 bits (378), Expect = 2e-36
Identities = 99/303 (32%), Positives = 156/303 (51%), Gaps = 12/303 (3%)
Query: 2 DNQAERESEAGVGLQRDEDDA-----------PLCEDVELQDGDLSPEEKIFLREFPRLK 50
D++A A L RDE D + +D D D + FL+EFPRLK
Sbjct: 31 DDEAWNGFVAAAELPRDEADELRKALNKLASHMVMKDKNRHDKD-QQHRQWFLKEFPRLK 89
Query: 51 EDLKGNIDKLRALADDIDKTHKKFTKANMVATSTAVISGVMSLLGLALAPATGGGSLLLS 110
+L+ +I KLRALA+++++ H+ T AN+V+ S SG+++LLGL LAP T G S +L
Sbjct: 90 RELEDHIRKLRALAEEVEQVHRGTTIANVVSNSVGTTSGILTLLGLGLAPFTEGISFVLL 149
Query: 111 TAGQGLATAAGVTSIVSGTLERSKNKEAQARAEDILPTYDQEDREDEEEKADYVTAAGKI 170
G GL AA V I +E A+A+A ++ + + +E +
Sbjct: 150 DTGMGLGAAAAVAGITCSVVELVNKLRARAQARNLDQSGTNVAKVMKEFVGGNTPNVLTL 209
Query: 171 IYNLRNTLKYAKKNVRAFWKLRANPRLANATKRLLTTGQVSSRSRVQVQKAFAGTTLAMT 230
+ N + +N+RA + RANP+L G++S+ QV++ G AM+
Sbjct: 210 VDNWYQVTQGIGRNIRAIRRARANPQLGAYAPPPHIIGRISAEGGEQVERVVEGPAQAMS 269
Query: 231 KNARVLGGVMSAFSLGYDLATLSKEWKHLKEGARTKFAEELRAKALELERKLTELTQLYK 290
+ ++G L D+ +L+ E KHL EGA+++ AEEL+ +A ELE KL LT++++
Sbjct: 270 RGTMIVGAATGGILLLLDVVSLAYESKHLLEGAKSESAEELKKRAQELEGKLNFLTKIHE 329
Query: 291 SLQ 293
LQ
Sbjct: 330 MLQ 332
>gi|22035653 apolipoprotein L2 [Homo sapiens]
Length = 337
Score = 150 bits (378), Expect = 2e-36
Identities = 99/303 (32%), Positives = 156/303 (51%), Gaps = 12/303 (3%)
Query: 2 DNQAERESEAGVGLQRDEDDA-----------PLCEDVELQDGDLSPEEKIFLREFPRLK 50
D++A A L RDE D + +D D D + FL+EFPRLK
Sbjct: 31 DDEAWNGFVAAAELPRDEADELRKALNKLASHMVMKDKNRHDKD-QQHRQWFLKEFPRLK 89
Query: 51 EDLKGNIDKLRALADDIDKTHKKFTKANMVATSTAVISGVMSLLGLALAPATGGGSLLLS 110
+L+ +I KLRALA+++++ H+ T AN+V+ S SG+++LLGL LAP T G S +L
Sbjct: 90 RELEDHIRKLRALAEEVEQVHRGTTIANVVSNSVGTTSGILTLLGLGLAPFTEGISFVLL 149
Query: 111 TAGQGLATAAGVTSIVSGTLERSKNKEAQARAEDILPTYDQEDREDEEEKADYVTAAGKI 170
G GL AA V I +E A+A+A ++ + + +E +
Sbjct: 150 DTGMGLGAAAAVAGITCSVVELVNKLRARAQARNLDQSGTNVAKVMKEFVGGNTPNVLTL 209
Query: 171 IYNLRNTLKYAKKNVRAFWKLRANPRLANATKRLLTTGQVSSRSRVQVQKAFAGTTLAMT 230
+ N + +N+RA + RANP+L G++S+ QV++ G AM+
Sbjct: 210 VDNWYQVTQGIGRNIRAIRRARANPQLGAYAPPPHIIGRISAEGGEQVERVVEGPAQAMS 269
Query: 231 KNARVLGGVMSAFSLGYDLATLSKEWKHLKEGARTKFAEELRAKALELERKLTELTQLYK 290
+ ++G L D+ +L+ E KHL EGA+++ AEEL+ +A ELE KL LT++++
Sbjct: 270 RGTMIVGAATGGILLLLDVVSLAYESKHLLEGAKSESAEELKKRAQELEGKLNFLTKIHE 329
Query: 291 SLQ 293
LQ
Sbjct: 330 MLQ 332
>gi|211938442 apolipoprotein L1 isoform c precursor [Homo sapiens]
Length = 380
Score = 145 bits (365), Expect = 7e-35
Identities = 93/254 (36%), Positives = 141/254 (55%), Gaps = 2/254 (0%)
Query: 42 FLREFPRLKEDLKGNIDKLRALADDIDKTHKKFTKANMVATSTAVISGVMSLLGLALAPA 101
FL+EFPRLK +L+ NI +LRALAD + K HK T AN+V+ S ++ SG+++L+G+ LAP
Sbjct: 122 FLKEFPRLKSELEDNIRRLRALADGVQKVHKGTTIANVVSGSLSISSGILTLVGMGLAPF 181
Query: 102 TGGGSLLLSTAGQGLATAAGVTSIVSGTLERSKNKEAQARAEDILPTYDQEDREDEEEKA 161
T GGSL+L G L A +T I S T++ K QA+A D++ + +E E
Sbjct: 182 TEGGSLVLLEPGMELGITAALTGITSSTMDYGKKWWTQAQAHDLVIKSLDKLKEVREFLG 241
Query: 162 DYVTAAGKIIYNLRNTLKYAKKNVRAFWKLRANPRLA--NATKRLLTTGQVSSRSRVQVQ 219
+ ++ + N + K++RA + RAN + + R T +S+ S QV+
Sbjct: 242 ENISNFLSLAGNTYQLTRGIGKDIRALRRARANLQSVPHASASRPRVTEPISAESGEQVE 301
Query: 220 KAFAGTTLAMTKNARVLGGVMSAFSLGYDLATLSKEWKHLKEGARTKFAEELRAKALELE 279
+ + L M++ ++ +F L D+ L E KHL EGA+++ AEEL+ A ELE
Sbjct: 302 RVNEPSILEMSRGVKLTDVAPVSFFLVLDVVYLVYESKHLHEGAKSETAEELKKVAQELE 361
Query: 280 RKLTELTQLYKSLQ 293
KL L YK LQ
Sbjct: 362 EKLNILNNNYKILQ 375
>gi|211938440 apolipoprotein L1 isoform a precursor [Homo sapiens]
Length = 398
Score = 145 bits (365), Expect = 7e-35
Identities = 93/254 (36%), Positives = 141/254 (55%), Gaps = 2/254 (0%)
Query: 42 FLREFPRLKEDLKGNIDKLRALADDIDKTHKKFTKANMVATSTAVISGVMSLLGLALAPA 101
FL+EFPRLK +L+ NI +LRALAD + K HK T AN+V+ S ++ SG+++L+G+ LAP
Sbjct: 140 FLKEFPRLKSELEDNIRRLRALADGVQKVHKGTTIANVVSGSLSISSGILTLVGMGLAPF 199
Query: 102 TGGGSLLLSTAGQGLATAAGVTSIVSGTLERSKNKEAQARAEDILPTYDQEDREDEEEKA 161
T GGSL+L G L A +T I S T++ K QA+A D++ + +E E
Sbjct: 200 TEGGSLVLLEPGMELGITAALTGITSSTMDYGKKWWTQAQAHDLVIKSLDKLKEVREFLG 259
Query: 162 DYVTAAGKIIYNLRNTLKYAKKNVRAFWKLRANPRLA--NATKRLLTTGQVSSRSRVQVQ 219
+ ++ + N + K++RA + RAN + + R T +S+ S QV+
Sbjct: 260 ENISNFLSLAGNTYQLTRGIGKDIRALRRARANLQSVPHASASRPRVTEPISAESGEQVE 319
Query: 220 KAFAGTTLAMTKNARVLGGVMSAFSLGYDLATLSKEWKHLKEGARTKFAEELRAKALELE 279
+ + L M++ ++ +F L D+ L E KHL EGA+++ AEEL+ A ELE
Sbjct: 320 RVNEPSILEMSRGVKLTDVAPVSFFLVLDVVYLVYESKHLHEGAKSETAEELKKVAQELE 379
Query: 280 RKLTELTQLYKSLQ 293
KL L YK LQ
Sbjct: 380 EKLNILNNNYKILQ 393
>gi|21735616 apolipoprotein L1 isoform b precursor [Homo sapiens]
Length = 414
Score = 145 bits (365), Expect = 7e-35
Identities = 93/254 (36%), Positives = 141/254 (55%), Gaps = 2/254 (0%)
Query: 42 FLREFPRLKEDLKGNIDKLRALADDIDKTHKKFTKANMVATSTAVISGVMSLLGLALAPA 101
FL+EFPRLK +L+ NI +LRALAD + K HK T AN+V+ S ++ SG+++L+G+ LAP
Sbjct: 156 FLKEFPRLKSELEDNIRRLRALADGVQKVHKGTTIANVVSGSLSISSGILTLVGMGLAPF 215
Query: 102 TGGGSLLLSTAGQGLATAAGVTSIVSGTLERSKNKEAQARAEDILPTYDQEDREDEEEKA 161
T GGSL+L G L A +T I S T++ K QA+A D++ + +E E
Sbjct: 216 TEGGSLVLLEPGMELGITAALTGITSSTMDYGKKWWTQAQAHDLVIKSLDKLKEVREFLG 275
Query: 162 DYVTAAGKIIYNLRNTLKYAKKNVRAFWKLRANPRLA--NATKRLLTTGQVSSRSRVQVQ 219
+ ++ + N + K++RA + RAN + + R T +S+ S QV+
Sbjct: 276 ENISNFLSLAGNTYQLTRGIGKDIRALRRARANLQSVPHASASRPRVTEPISAESGEQVE 335
Query: 220 KAFAGTTLAMTKNARVLGGVMSAFSLGYDLATLSKEWKHLKEGARTKFAEELRAKALELE 279
+ + L M++ ++ +F L D+ L E KHL EGA+++ AEEL+ A ELE
Sbjct: 336 RVNEPSILEMSRGVKLTDVAPVSFFLVLDVVYLVYESKHLHEGAKSETAEELKKVAQELE 395
Query: 280 RKLTELTQLYKSLQ 293
KL L YK LQ
Sbjct: 396 EKLNILNNNYKILQ 409
>gi|21735614 apolipoprotein L1 isoform a precursor [Homo sapiens]
Length = 398
Score = 145 bits (365), Expect = 7e-35
Identities = 93/254 (36%), Positives = 141/254 (55%), Gaps = 2/254 (0%)
Query: 42 FLREFPRLKEDLKGNIDKLRALADDIDKTHKKFTKANMVATSTAVISGVMSLLGLALAPA 101
FL+EFPRLK +L+ NI +LRALAD + K HK T AN+V+ S ++ SG+++L+G+ LAP
Sbjct: 140 FLKEFPRLKSELEDNIRRLRALADGVQKVHKGTTIANVVSGSLSISSGILTLVGMGLAPF 199
Query: 102 TGGGSLLLSTAGQGLATAAGVTSIVSGTLERSKNKEAQARAEDILPTYDQEDREDEEEKA 161
T GGSL+L G L A +T I S T++ K QA+A D++ + +E E
Sbjct: 200 TEGGSLVLLEPGMELGITAALTGITSSTMDYGKKWWTQAQAHDLVIKSLDKLKEVREFLG 259
Query: 162 DYVTAAGKIIYNLRNTLKYAKKNVRAFWKLRANPRLA--NATKRLLTTGQVSSRSRVQVQ 219
+ ++ + N + K++RA + RAN + + R T +S+ S QV+
Sbjct: 260 ENISNFLSLAGNTYQLTRGIGKDIRALRRARANLQSVPHASASRPRVTEPISAESGEQVE 319
Query: 220 KAFAGTTLAMTKNARVLGGVMSAFSLGYDLATLSKEWKHLKEGARTKFAEELRAKALELE 279
+ + L M++ ++ +F L D+ L E KHL EGA+++ AEEL+ A ELE
Sbjct: 320 RVNEPSILEMSRGVKLTDVAPVSFFLVLDVVYLVYESKHLHEGAKSETAEELKKVAQELE 379
Query: 280 RKLTELTQLYKSLQ 293
KL L YK LQ
Sbjct: 380 EKLNILNNNYKILQ 393
>gi|22035650 apolipoprotein L3 isoform 3 [Homo sapiens]
Length = 202
Score = 118 bits (296), Expect = 7e-27
Identities = 76/202 (37%), Positives = 105/202 (51%), Gaps = 6/202 (2%)
Query: 91 MSLLGLALAPATGGGSLLLSTAGQGLATAAGVTSIVSGTLERSKNKEAQARAEDILPTYD 150
MSL GL LAP T G SL L+ AG GL A+ VT I + +E S A+A A + T
Sbjct: 1 MSLAGLVLAPFTAGTSLALTAAGVGLGAASAVTGITTSIVEHSYTSSAEAEASRLTATSI 60
Query: 151 QEDREDEEEKADYVTAAGKIIYNLRNTLKYAKKNVRAFWKLRANPRLANATKRLLTTGQV 210
+ +E D ++ N + +RA + RA RL +TT ++
Sbjct: 61 DRLKVFKEVMRDITPNLLSLLNNYYEATQTIGSEIRAIRQARARARLP------VTTWRI 114
Query: 211 SSRSRVQVQKAFAGTTLAMTKNARVLGGVMSAFSLGYDLATLSKEWKHLKEGARTKFAEE 270
S+ S Q ++ AGTT A+++ AR+L S L D+ L E KHL EGA++ AEE
Sbjct: 115 SAGSGGQAERTIAGTTRAVSRGARILSATTSGIFLALDVVNLVYESKHLHEGAKSASAEE 174
Query: 271 LRAKALELERKLTELTQLYKSL 292
LR +A ELE L ELTQ+Y+ L
Sbjct: 175 LRRQAQELEENLMELTQIYQRL 196
>gi|22035648 apolipoprotein L3 isoform 3 [Homo sapiens]
Length = 202
Score = 118 bits (296), Expect = 7e-27
Identities = 76/202 (37%), Positives = 105/202 (51%), Gaps = 6/202 (2%)
Query: 91 MSLLGLALAPATGGGSLLLSTAGQGLATAAGVTSIVSGTLERSKNKEAQARAEDILPTYD 150
MSL GL LAP T G SL L+ AG GL A+ VT I + +E S A+A A + T
Sbjct: 1 MSLAGLVLAPFTAGTSLALTAAGVGLGAASAVTGITTSIVEHSYTSSAEAEASRLTATSI 60
Query: 151 QEDREDEEEKADYVTAAGKIIYNLRNTLKYAKKNVRAFWKLRANPRLANATKRLLTTGQV 210
+ +E D ++ N + +RA + RA RL +TT ++
Sbjct: 61 DRLKVFKEVMRDITPNLLSLLNNYYEATQTIGSEIRAIRQARARARLP------VTTWRI 114
Query: 211 SSRSRVQVQKAFAGTTLAMTKNARVLGGVMSAFSLGYDLATLSKEWKHLKEGARTKFAEE 270
S+ S Q ++ AGTT A+++ AR+L S L D+ L E KHL EGA++ AEE
Sbjct: 115 SAGSGGQAERTIAGTTRAVSRGARILSATTSGIFLALDVVNLVYESKHLHEGAKSASAEE 174
Query: 271 LRAKALELERKLTELTQLYKSL 292
LR +A ELE L ELTQ+Y+ L
Sbjct: 175 LRRQAQELEENLMELTQIYQRL 196
>gi|19923626 apolipoprotein L4 isoform 1 [Homo sapiens]
Length = 348
Score = 104 bits (259), Expect = 1e-22
Identities = 90/295 (30%), Positives = 149/295 (50%), Gaps = 32/295 (10%)
Query: 15 LQRDEDDA------PLCEDVELQDGDLSPEEKIF----LREFPRLKEDLKGNIDKLRALA 64
L R+E DA L V ++D D+ +E+ F L+EFP+++ ++ +I++LR +A
Sbjct: 68 LPREEADALYEALKNLTPYVAIEDKDMQQKEQQFREWFLKEFPQIRWKIQESIERLRVIA 127
Query: 65 DDIDKTHKKFTKANMVATSTAVISGVMSLLGLALAPATGGGSLLLSTAGQGLATAAGVTS 124
++I+K H+ AN+V+ ST G++S++G+ LAP T G SL ++ AG GL A+
Sbjct: 128 NEIEKVHRGCVIANVVSGST----GILSVIGVMLAPFTAGLSLSITAAGVGLGIASATAG 183
Query: 125 IVSGTLERSKNKEAQARAEDILPTYDQEDREDEEEKADYVTAAGKIIYNLR-NTLKYAKK 183
I S +E + + A+ A + T D + A I+ ++ N L +A
Sbjct: 184 IASSIVENTYTRSAELTASRLTAT-----------STDQLEALRDILRDITPNVLSFALD 232
Query: 184 NVRAFWKLRANP----RLANAT-KRLLTTGQVSSRSRVQVQKAFAGTTLAMTKNARVLGG 238
A K+ AN R + AT R L + + V+ + T + K AR LG
Sbjct: 233 FDEA-TKMIANDVHTLRRSKATVGRPLIAWRYVPINVVETLRTRGAPTRIVRKVARNLGK 291
Query: 239 VMSAFSLGYDLATLSKEWKHLKEGARTKFAEELRAKALELERKLTELTQLYKSLQ 293
S + D+ L ++ L +GA+++ AE LR A ELE L ELT +++SL+
Sbjct: 292 ATSGVLVVLDVVNLVQDSLDLHKGAKSESAESLRQWAQELEENLNELTHIHQSLK 346
>gi|22035657 apolipoprotein L4 isoform 2 precursor [Homo sapiens]
Length = 351
Score = 104 bits (259), Expect = 1e-22
Identities = 90/295 (30%), Positives = 149/295 (50%), Gaps = 32/295 (10%)
Query: 15 LQRDEDDA------PLCEDVELQDGDLSPEEKIF----LREFPRLKEDLKGNIDKLRALA 64
L R+E DA L V ++D D+ +E+ F L+EFP+++ ++ +I++LR +A
Sbjct: 71 LPREEADALYEALKNLTPYVAIEDKDMQQKEQQFREWFLKEFPQIRWKIQESIERLRVIA 130
Query: 65 DDIDKTHKKFTKANMVATSTAVISGVMSLLGLALAPATGGGSLLLSTAGQGLATAAGVTS 124
++I+K H+ AN+V+ ST G++S++G+ LAP T G SL ++ AG GL A+
Sbjct: 131 NEIEKVHRGCVIANVVSGST----GILSVIGVMLAPFTAGLSLSITAAGVGLGIASATAG 186
Query: 125 IVSGTLERSKNKEAQARAEDILPTYDQEDREDEEEKADYVTAAGKIIYNLR-NTLKYAKK 183
I S +E + + A+ A + T D + A I+ ++ N L +A
Sbjct: 187 IASSIVENTYTRSAELTASRLTAT-----------STDQLEALRDILRDITPNVLSFALD 235
Query: 184 NVRAFWKLRANP----RLANAT-KRLLTTGQVSSRSRVQVQKAFAGTTLAMTKNARVLGG 238
A K+ AN R + AT R L + + V+ + T + K AR LG
Sbjct: 236 FDEA-TKMIANDVHTLRRSKATVGRPLIAWRYVPINVVETLRTRGAPTRIVRKVARNLGK 294
Query: 239 VMSAFSLGYDLATLSKEWKHLKEGARTKFAEELRAKALELERKLTELTQLYKSLQ 293
S + D+ L ++ L +GA+++ AE LR A ELE L ELT +++SL+
Sbjct: 295 ATSGVLVVLDVVNLVQDSLDLHKGAKSESAESLRQWAQELEENLNELTHIHQSLK 349
>gi|194353995 apolipoprotein L domain containing 1 isoform 1 [Homo
sapiens]
Length = 279
Score = 57.8 bits (138), Expect = 1e-08
Identities = 37/117 (31%), Positives = 60/117 (51%), Gaps = 4/117 (3%)
Query: 43 LREFPRLKED----LKGNIDKLRALADDIDKTHKKFTKANMVATSTAVISGVMSLLGLAL 98
LR F L D L G + +LR +A +++ ++ AN+ +S + + +++GL+L
Sbjct: 48 LRRFQGLLLDRRGRLHGQVLRLREVARRLERLRRRSLVANVAGSSLSATGALAAIVGLSL 107
Query: 99 APATGGGSLLLSTAGQGLATAAGVTSIVSGTLERSKNKEAQARAEDILPTYDQEDRE 155
+P T G SLL+S G G+ATA G +I S N R ++I T + RE
Sbjct: 108 SPVTLGTSLLVSAVGLGVATAGGAVTITSDLSLIFCNSRELRRVQEIAATCQDQMRE 164
>gi|194353993 apolipoprotein L domain containing 1 isoform 2 [Homo
sapiens]
Length = 248
Score = 57.8 bits (138), Expect = 1e-08
Identities = 37/117 (31%), Positives = 60/117 (51%), Gaps = 4/117 (3%)
Query: 43 LREFPRLKED----LKGNIDKLRALADDIDKTHKKFTKANMVATSTAVISGVMSLLGLAL 98
LR F L D L G + +LR +A +++ ++ AN+ +S + + +++GL+L
Sbjct: 17 LRRFQGLLLDRRGRLHGQVLRLREVARRLERLRRRSLVANVAGSSLSATGALAAIVGLSL 76
Query: 99 APATGGGSLLLSTAGQGLATAAGVTSIVSGTLERSKNKEAQARAEDILPTYDQEDRE 155
+P T G SLL+S G G+ATA G +I S N R ++I T + RE
Sbjct: 77 SPVTLGTSLLVSAVGLGVATAGGAVTITSDLSLIFCNSRELRRVQEIAATCQDQMRE 133
>gi|24429572 TBP-associated factor RNA polymerase 1-like [Homo
sapiens]
Length = 1826
Score = 32.0 bits (71), Expect = 0.83
Identities = 20/74 (27%), Positives = 33/74 (44%)
Query: 251 TLSKEWKHLKEGARTKFAEELRAKALELERKLTELTQLYKSLQQKVRSRARGVGKDLTGT 310
T+S E H EG +KFA R E + + E Q LQ KV S + D
Sbjct: 1050 TMSTEQAHSGEGPMSKFARGSRFSVAEHQERYKEECQRIFDLQNKVLSSTEVLSTDTDSI 1109
Query: 311 CETEAYWKELREHV 324
++ ++E+ +++
Sbjct: 1110 SAEDSDFEEMGKNI 1123
>gi|7705415 hook homolog 1 [Homo sapiens]
Length = 728
Score = 31.6 bits (70), Expect = 1.1
Identities = 66/304 (21%), Positives = 113/304 (37%), Gaps = 48/304 (15%)
Query: 4 QAERESEAGVGLQRDEDDAPL-CEDVELQDGDLSPEEKIFLREFPRLKEDLKGNIDKLRA 62
Q E+ E L+ +DD + CE++E Q L EF ++L ++ RA
Sbjct: 253 QLEQLQEENFRLEAAKDDYRVHCEELEKQ-----------LIEFQHRNDELTSLAEETRA 301
Query: 63 LADDIDKTHKKFTKANMVATSTAVISGVMSLLGLALAPATGGGSLLLSTAGQGLATAAGV 122
L D+ID KAN + ++ + + L L + L +
Sbjct: 302 LKDEIDVLRATSDKANKLESTVEIYRQKLQDLN------------DLRKQVKTLQETNMM 349
Query: 123 TSIVSGTLERSKNKEAQARAEDILPTYDQEDRE------DEEEKADYVTAAGKIIYNLRN 176
+ +LE K AR + L TY ++ ++ E ++AD + K +
Sbjct: 350 YMHNTVSLEEELKKANAARTQ--LETYKRQVQDLHVKLSSESKRADTLAFEMKRLEEKHE 407
Query: 177 TLKYAKKNVRAFWKLRANPRLANATKRLLTTGQVSSRSRVQVQKAFAGTTLAMTKNARVL 236
L L+ RL L T + S+VQ Q T + TK+ L
Sbjct: 408 AL------------LKEKERLIEQRDTLKETNEELRCSQVQ-QDHLNQTDASATKSYENL 454
Query: 237 GGVMSAFSLGYDLATLSKEWKHLK---EGARTKFAEELRAKALELERKLTELTQLYKSLQ 293
+ L E K L+ EG+ + EEL+ + + RK+ EL + +
Sbjct: 455 AAEIMPVEYREVFIRLQHENKMLRLQQEGSENERIEELQEQLEQKHRKMNELETEQRLSK 514
Query: 294 QKVR 297
+++R
Sbjct: 515 ERIR 518
>gi|31982906 cingulin-like 1 [Homo sapiens]
Length = 1302
Score = 31.6 bits (70), Expect = 1.1
Identities = 62/296 (20%), Positives = 115/296 (38%), Gaps = 39/296 (13%)
Query: 18 DEDDAPLCEDV-----ELQDGDLSPEEKI-FLREFPRLKEDLKGNI-DKLRALADDIDKT 70
D + L E++ +LQD ++ EE+ LR+ R LKG + +++ + ++DK
Sbjct: 722 DREKGALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELTALKGALKEEVSSHDQEMDKL 781
Query: 71 HKKFTKANMVATSTAVISGVMSLLGLALAPATGGGSLLLSTAGQGLATAAGVTSIVSGTL 130
+++ + L ++ AT +L S + AG V L
Sbjct: 782 KEQY-------------DAELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVK--L 826
Query: 131 ERSKNKEAQARAEDILPTYDQEDREDEEEKADYVTAAGKI------IYNLRNTLKYAKKN 184
+ +N++ Q R+E++ Q R+ E+ K D A + I L L +A+K
Sbjct: 827 LQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKE 886
Query: 185 VRAFWKLRANPRLANATKRLLTTGQVSSRSRVQVQKAFAGTTLAMTKNARVLGGVMS--- 241
+ R A + L Q + Q QK + ++ L + +
Sbjct: 887 EKEAVSAR------RALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNEME 940
Query: 242 --AFSLGYDLATLSKEWKHLKEGARTKFAEELRAKALELERKLTELTQLYKSLQQK 295
+ LG + L KE + E +RT E E+ EL ++ + L++K
Sbjct: 941 NERWHLGKTIEKLQKEMADIVEASRTSTLELQNQLDEYKEKNRRELAEMQRQLKEK 996
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 31.2 bits (69), Expect = 1.4
Identities = 44/174 (25%), Positives = 75/174 (43%), Gaps = 17/174 (9%)
Query: 133 SKNKEAQARAEDILPTYDQEDREDEEEKADYVTAAGKIIYNLRNTLKYAKKNVRAFWKLR 192
SK+KE Q + E+ + T ++E + EEK VT + I + +K RA K
Sbjct: 1531 SKSKEQQYKDEEEV-TLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRA 1589
Query: 193 ANPR-LANATKRLLTTGQVSSRSRVQVQKAFAGTTLAMTKNARVLGGVMSAFSLGYDLAT 251
R LA ++L R Q ++ A + +T++ R + F+ + T
Sbjct: 1590 QEERKLAQEEEKLAQ----EERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEE--T 1643
Query: 252 LSKEWKHLKEGA------RTKFAEELRAKALE---LERKLTELTQLYKSLQQKV 296
L++ + L + A R K A++ A E L +K +L ++ L QKV
Sbjct: 1644 LAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKV 1697
>gi|157738667 FYVE and coiled-coil domain containing 1 [Homo sapiens]
Length = 1478
Score = 31.2 bits (69), Expect = 1.4
Identities = 25/76 (32%), Positives = 37/76 (48%), Gaps = 10/76 (13%)
Query: 260 KEGARTKFAEELRAKALELERKLTELTQLYKSLQQKVRSRARGVGK---DLTGTCETEAY 316
KEGA + E+L ELE+ T++ + Y L Q+V +R R K DL T+ Y
Sbjct: 1079 KEGAALR--EDLERTQKELEKATTKIQEYYNKLCQEVTNRERNDQKMLADLDDLNRTKKY 1136
Query: 317 WKE-----LREHVWMW 327
+E LR+ +W
Sbjct: 1137 LEERLIELLRDKDALW 1152
>gi|46852174 kinesin family member 3A [Homo sapiens]
Length = 699
Score = 30.8 bits (68), Expect = 1.8
Identities = 21/83 (25%), Positives = 43/83 (51%), Gaps = 6/83 (7%)
Query: 246 GYDLATLSKEWKHLKEGA------RTKFAEELRAKALELERKLTELTQLYKSLQQKVRSR 299
G DL ++E + L E + R K AE+LR + E E++ ++ + Y SLQ++ + +
Sbjct: 483 GVDLLAKAEEQEKLLEESNMELEERRKRAEQLRRELEEKEQERLDIEEKYTSLQEEAQGK 542
Query: 300 ARGVGKDLTGTCETEAYWKELRE 322
+ + K T ++ +L++
Sbjct: 543 TKKLKKVWTMLMAAKSEMADLQQ 565
>gi|12669915 E2F transcription factor 4 [Homo sapiens]
Length = 413
Score = 30.8 bits (68), Expect = 1.8
Identities = 32/117 (27%), Positives = 54/117 (46%), Gaps = 13/117 (11%)
Query: 204 LLTTGQVSSRSRVQ---VQKAFAGTTLAMTKNARV--LGGVMSAFSLGYDLATLSKEWKH 258
LLTT VS + + A TLA+ + R+ + V+ L + S +WK
Sbjct: 24 LLTTKFVSLLQEAKDGVLDLKLAADTLAVRQKRRIYDITNVLEGIGLIEKKSKNSIQWKG 83
Query: 259 LKEGARTKFAE----ELRAKALELERKLTELTQLYKSLQQKVRSRARGVGKDLTGTC 311
+ G T+ EL+A+ EL+++ EL Q +QQ +R+ V +D+ +C
Sbjct: 84 VGPGCNTREIADKLIELKAEIEELQQREQELDQHKVWVQQSIRN----VTEDVQNSC 136
>gi|38348729 hypothetical protein LOC203238 [Homo sapiens]
Length = 1326
Score = 30.8 bits (68), Expect = 1.8
Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 6/70 (8%)
Query: 244 SLGYDLATLSKEWKHLKEGARTKFAE------ELRAKALELERKLTELTQLYKSLQQKVR 297
SL YDLA KE + A + AE +L A+ EL+ K E + +++ QQK +
Sbjct: 83 SLEYDLAVARKEAGLGRRAAEERLAEAHRIQEKLCAQNSELQAKTNETEKAFQTSQQKWK 142
Query: 298 SRARGVGKDL 307
R DL
Sbjct: 143 EECRRFEHDL 152
>gi|29171682 interleukin 9 receptor precursor [Homo sapiens]
Length = 521
Score = 30.4 bits (67), Expect = 2.4
Identities = 13/29 (44%), Positives = 17/29 (58%), Gaps = 4/29 (13%)
Query: 310 TCETEAYWKELREHVWMWLWLCVCLCVCV 338
T E+EA LR + WL C+C+C CV
Sbjct: 12 TLESEA----LRRDMGTWLLACICICTCV 36
>gi|19923312 v-myc myelocytomatosis viral related oncogene,
neuroblastoma derived [Homo sapiens]
Length = 464
Score = 30.4 bits (67), Expect = 2.4
Identities = 25/74 (33%), Positives = 33/74 (44%), Gaps = 7/74 (9%)
Query: 99 APATGGGSLLLSTAGQGLATAAGVTSIVS---GTLERS--KNKEAQARAEDILPTYDQED 153
APA+ + +G G+A AG + G + S +K ED L D ED
Sbjct: 208 APASAPAAGPAVASGAGIAAPAGAPGVAPPRPGGRQTSGGDHKALSTSGEDTLSDSDDED 267
Query: 154 RE--DEEEKADYVT 165
E DEEE+ D VT
Sbjct: 268 DEEEDEEEEIDVVT 281
>gi|4506671 ribosomal protein P2 [Homo sapiens]
Length = 115
Score = 30.4 bits (67), Expect = 2.4
Identities = 23/95 (24%), Positives = 43/95 (45%), Gaps = 6/95 (6%)
Query: 51 EDLKGNIDKLRALADDIDKTHKKFTKANMVATSTAVISGVMSLLGLALAPATGGGSLLLS 110
+D+K +D + ADD D+ +K ++ N + G+ L A GG++ +S
Sbjct: 21 KDIKKILDSVGIEADD-DRLNKVISELNGKNIEDVIAQGIGKL-----ASVPAGGAVAVS 74
Query: 111 TAGQGLATAAGVTSIVSGTLERSKNKEAQARAEDI 145
A A AAG + + K +E++ +D+
Sbjct: 75 AAPGSAAPAAGSAPAAAEEKKDEKKEESEESDDDM 109
>gi|35493713 vacuolar protein sorting 13B isoform 5 [Homo sapiens]
Length = 4022
Score = 30.0 bits (66), Expect = 3.1
Identities = 23/75 (30%), Positives = 37/75 (49%), Gaps = 7/75 (9%)
Query: 57 IDKLRALADDIDKTHKKFTKANMVATSTA-----VISGV-MSLLGLALAPATGGGSLLLS 110
I L A+A +D+ + F K + S VISGV ++G+ P GG + L+S
Sbjct: 3760 ISLLGAIAGIVDQPMQNFQKTSEAQASAGHKAKGVISGVGKGIMGVFTKPI-GGAAELVS 3818
Query: 111 TAGQGLATAAGVTSI 125
G G+ AG++ +
Sbjct: 3819 QTGYGILHGAGLSQL 3833
>gi|35493701 vacuolar protein sorting 13B isoform 1 [Homo sapiens]
Length = 3997
Score = 30.0 bits (66), Expect = 3.1
Identities = 23/75 (30%), Positives = 37/75 (49%), Gaps = 7/75 (9%)
Query: 57 IDKLRALADDIDKTHKKFTKANMVATSTA-----VISGV-MSLLGLALAPATGGGSLLLS 110
I L A+A +D+ + F K + S VISGV ++G+ P GG + L+S
Sbjct: 3735 ISLLGAIAGIVDQPMQNFQKTSEAQASAGHKAKGVISGVGKGIMGVFTKPI-GGAAELVS 3793
Query: 111 TAGQGLATAAGVTSI 125
G G+ AG++ +
Sbjct: 3794 QTGYGILHGAGLSQL 3808
>gi|148762940 DVL-binding protein DAPLE [Homo sapiens]
Length = 2028
Score = 30.0 bits (66), Expect = 3.1
Identities = 21/75 (28%), Positives = 37/75 (49%), Gaps = 1/75 (1%)
Query: 6 ERESEA-GVGLQRDEDDAPLCEDVELQDGDLSPEEKIFLREFPRLKEDLKGNIDKLRALA 64
E+ES A L R D A +++E + DL+ + + R L+EDL K + L+
Sbjct: 866 EKESRALDKELARCRDAAGKLKELEKDNRDLTKQVTVHARTLTTLREDLVLEKLKSQQLS 925
Query: 65 DDIDKTHKKFTKANM 79
++DK ++ K +
Sbjct: 926 SELDKLSQELEKVGL 940
>gi|62865871 coiled-coil domain containing 132 isoform a [Homo
sapiens]
Length = 964
Score = 30.0 bits (66), Expect = 3.1
Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 4/76 (5%)
Query: 133 SKNKEAQARAEDILPTYDQEDREDEEEKADYV---TAAGKIIYNLRNTLKYAKKNVRAFW 189
S E+ + + YD + EE K DYV T G + R TLK KK+ +
Sbjct: 541 SNGYESDEQEKSAYQEYDSDSDVPEELKRDYVDEQTGDGPVKSVSRETLKSRKKSDYSLN 600
Query: 190 KLRANPRLANATKRLL 205
K+ A P L N T ++
Sbjct: 601 KVNA-PILTNTTLNVI 615
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.130 0.371
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,466,618
Number of Sequences: 37866
Number of extensions: 472495
Number of successful extensions: 3534
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 29
Number of HSP's that attempted gapping in prelim test: 3437
Number of HSP's gapped (non-prelim): 104
length of query: 343
length of database: 18,247,518
effective HSP length: 103
effective length of query: 240
effective length of database: 14,347,320
effective search space: 3443356800
effective search space used: 3443356800
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.