Search of human proteins with 61102721

Search of human proteins with 61102721

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|61102721 PRAME family member 9 [Homo sapiens]
         (478 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|148356236 PRAME family member 15 [Homo sapiens]                    978   0.0  
gi|61102721 PRAME family member 9 [Homo sapiens]                      978   0.0  
gi|59958373 PRAME family member 4 [Homo sapiens]                      962   0.0  
gi|61696142 PRAME family member 5 [Homo sapiens]                      944   0.0  
gi|239741043 PREDICTED: PRAME family member 11 [Homo sapiens]         941   0.0  
gi|239741045 PREDICTED: PRAME family member 23 [Homo sapiens]         939   0.0  
gi|58219004 PRAME family member 6 [Homo sapiens]                      939   0.0  
gi|226437621 PRAME family member 11 [Homo sapiens]                    867   0.0  
gi|153792112 PRAME family member 20 [Homo sapiens]                    788   0.0  
gi|153945800 PRAME family member 21 [Homo sapiens]                    788   0.0  
gi|88942379 PREDICTED: PRAME family member [Homo sapiens]             764   0.0  
gi|239741047 PREDICTED: PRAME family member 25-like [Homo sapiens]    675   0.0  
gi|239741053 PREDICTED: similar to Putative PRAME family member ...   575   e-164
gi|59676593 PRAME family member 7 [Homo sapiens]                      574   e-164
gi|59676587 PRAME family member 8 [Homo sapiens]                      573   e-164
gi|124249372 PRAME family member 12 [Homo sapiens]                    570   e-163
gi|46249373 preferentially expressed antigen in melanoma [Homo s...   447   e-125
gi|46249371 preferentially expressed antigen in melanoma [Homo s...   447   e-125
gi|46249369 preferentially expressed antigen in melanoma [Homo s...   447   e-125
gi|46249367 preferentially expressed antigen in melanoma [Homo s...   447   e-125
gi|5174641 preferentially expressed antigen in melanoma [Homo sa...   447   e-125
gi|154800493 PRAME family member 22 [Homo sapiens]                    426   e-119
gi|194306638 PRAME family member 3 [Homo sapiens]                     420   e-117
gi|153791443 PRAME family member 18 [Homo sapiens]                    418   e-117
gi|113865933 PRAME family member 16 [Homo sapiens]                    415   e-116
gi|194306635 PRAME family member 19 [Homo sapiens]                    414   e-116
gi|157426839 PRAME family member 17 [Homo sapiens]                    412   e-115
gi|66954681 PRAME family member 13 [Homo sapiens]                     410   e-114
gi|12738831 PRAME family member 1 [Homo sapiens]                      409   e-114
gi|194018546 PRAME family member 10 [Homo sapiens]                    408   e-114

>gi|148356236 PRAME family member 15 [Homo sapiens]
          Length = 478

 Score =  978 bits (2527), Expect = 0.0
 Identities = 478/478 (100%), Positives = 478/478 (100%)

Query: 1   MKMSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQA 60
           MKMSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQA
Sbjct: 1   MKMSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQA 60

Query: 61  WPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSE 120
           WPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSE
Sbjct: 61  WPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSE 120

Query: 121 AMAHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLL 180
           AMAHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLL
Sbjct: 121 AMAHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLL 180

Query: 181 HLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLV 240
           HLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLV
Sbjct: 181 HLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLV 240

Query: 241 LSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKV 300
           LSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKV
Sbjct: 241 LSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKV 300

Query: 301 LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD 360
           LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD
Sbjct: 301 LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD 360

Query: 361 DCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRE 420
           DCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRE
Sbjct: 361 DCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRE 420

Query: 421 SYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC 478
           SYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC
Sbjct: 421 SYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC 478


>gi|61102721 PRAME family member 9 [Homo sapiens]
          Length = 478

 Score =  978 bits (2527), Expect = 0.0
 Identities = 478/478 (100%), Positives = 478/478 (100%)

Query: 1   MKMSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQA 60
           MKMSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQA
Sbjct: 1   MKMSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQA 60

Query: 61  WPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSE 120
           WPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSE
Sbjct: 61  WPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSE 120

Query: 121 AMAHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLL 180
           AMAHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLL
Sbjct: 121 AMAHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLL 180

Query: 181 HLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLV 240
           HLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLV
Sbjct: 181 HLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLV 240

Query: 241 LSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKV 300
           LSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKV
Sbjct: 241 LSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKV 300

Query: 301 LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD 360
           LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD
Sbjct: 301 LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD 360

Query: 361 DCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRE 420
           DCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRE
Sbjct: 361 DCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRE 420

Query: 421 SYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC 478
           SYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC
Sbjct: 421 SYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC 478


>gi|59958373 PRAME family member 4 [Homo sapiens]
          Length = 478

 Score =  962 bits (2486), Expect = 0.0
 Identities = 470/478 (98%), Positives = 473/478 (98%)

Query: 1   MKMSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQA 60
           MKMSI TPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQ+
Sbjct: 1   MKMSIWTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQS 60

Query: 61  WPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSE 120
           WPFRRLPLRPLIKMPCLEAFQAVLDGLDALL  GVRPRRWKLQVLDLQDVCENFWMVWSE
Sbjct: 61  WPFRRLPLRPLIKMPCLEAFQAVLDGLDALLNLGVRPRRWKLQVLDLQDVCENFWMVWSE 120

Query: 121 AMAHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLL 180
           AMAHGCFLNAKRNKKPV+DCPRMRGRQPLTVFVELWLKNRTLDEYLT LLLWVKQRKDLL
Sbjct: 121 AMAHGCFLNAKRNKKPVEDCPRMRGRQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLL 180

Query: 181 HLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLV 240
           HLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKL+
Sbjct: 181 HLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLI 240

Query: 241 LSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKV 300
           LSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLK 
Sbjct: 241 LSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKF 300

Query: 301 LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD 360
           LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD
Sbjct: 301 LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD 360

Query: 361 DCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRE 420
           DCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRE
Sbjct: 361 DCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRE 420

Query: 421 SYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC 478
           SYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC
Sbjct: 421 SYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC 478


>gi|61696142 PRAME family member 5 [Homo sapiens]
          Length = 476

 Score =  944 bits (2441), Expect = 0.0
 Identities = 466/476 (97%), Positives = 467/476 (98%)

Query: 3   MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 62
           MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP
Sbjct: 1   MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60

Query: 63  FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
           FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGV PRRWKLQVLDLQDVCENFWMVWSEAM
Sbjct: 61  FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120

Query: 123 AHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLLHL 182
           AHGCFLNAKRNKKPVQDCPRMRG+QPLTVFVELWLKNRTLDEYLT LLLWVKQRKDLLHL
Sbjct: 121 AHGCFLNAKRNKKPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180

Query: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 242
           CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS
Sbjct: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 240

Query: 243 HMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLT 302
           HMDVSRYVSPEQKKEIVTQFTTQFLKL CLQKL MNSVSFLEGHLDQLLSCLKTSLKVLT
Sbjct: 241 HMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVLT 300

Query: 303 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 362
           ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC
Sbjct: 301 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 360

Query: 363 GIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRESY 422
           GIIDSQVNAILPALSRCFELNTFSFCGNPI MATLENLLSHTIILKNLCVELYPAPRESY
Sbjct: 361 GIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRESY 420

Query: 423 GADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC 478
            ADGTLCWSRFAQIRAELM RVRDLRHPKRILFCTD CPDCGNRSFYDLEADQ CC
Sbjct: 421 DADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQCCC 476


>gi|239741043 PREDICTED: PRAME family member 11 [Homo sapiens]
          Length = 513

 Score =  941 bits (2433), Expect = 0.0
 Identities = 461/478 (96%), Positives = 469/478 (98%)

Query: 1   MKMSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQA 60
           MKMSIR PPRLLEL GRSLLRDQALA+STLEELPTELFPPLFMEAFSRRRCEALKLMVQA
Sbjct: 36  MKMSIRIPPRLLELXGRSLLRDQALAVSTLEELPTELFPPLFMEAFSRRRCEALKLMVQA 95

Query: 61  WPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSE 120
           WPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSE
Sbjct: 96  WPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSE 155

Query: 121 AMAHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLL 180
           AMAHGCFLNAKRNK PVQDCPRMR RQPLTVFVELWLKNRTLDEYLT LLLWVKQR+DLL
Sbjct: 156 AMAHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTLDEYLTCLLLWVKQRRDLL 215

Query: 181 HLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLV 240
           HLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKW+LPILTQFTPYLGH+RNLQKLV
Sbjct: 216 HLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPILTQFTPYLGHLRNLQKLV 275

Query: 241 LSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKV 300
           LSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKV
Sbjct: 276 LSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKV 335

Query: 301 LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD 360
           LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD
Sbjct: 336 LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD 395

Query: 361 DCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRE 420
           DCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLC+ELYPAP+E
Sbjct: 396 DCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCLELYPAPQE 455

Query: 421 SYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC 478
           SYGADGTLCWSRFAQIRAELM +VR LRHPKRILFCTD CPD G+RSFYDLEADQYCC
Sbjct: 456 SYGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPDHGDRSFYDLEADQYCC 513


>gi|239741045 PREDICTED: PRAME family member 23 [Homo sapiens]
          Length = 476

 Score =  939 bits (2428), Expect = 0.0
 Identities = 464/476 (97%), Positives = 465/476 (97%)

Query: 3   MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 62
           MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP
Sbjct: 1   MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60

Query: 63  FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
           FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGV PRRWKLQVLDLQDVCENFWMVWSEAM
Sbjct: 61  FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120

Query: 123 AHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLLHL 182
           AHGCFLNAKRNKKPVQDCPRMRG+QPLTVFVELWLKNRTLDEYLT LLLWVKQRKDLLHL
Sbjct: 121 AHGCFLNAKRNKKPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180

Query: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 242
           CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS
Sbjct: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 240

Query: 243 HMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLT 302
           HMDVSRYVSPEQKKEIVTQFTTQFLKL CLQKL MNSVSFLEGHLDQLLSCLKTSLKVLT
Sbjct: 241 HMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVLT 300

Query: 303 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 362
           ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC
Sbjct: 301 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 360

Query: 363 GIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRESY 422
           GIIDSQVNAILPALS CFELNTFSFCGNPI MATLENLLSHTIILKNLCVELYPAPRESY
Sbjct: 361 GIIDSQVNAILPALSCCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRESY 420

Query: 423 GADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC 478
            ADGTLCWSRF QIRAELM RVRDLRHPKRILFCTD CPDCGNRSFYDLEADQ CC
Sbjct: 421 DADGTLCWSRFPQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQCCC 476


>gi|58219004 PRAME family member 6 [Homo sapiens]
          Length = 476

 Score =  939 bits (2427), Expect = 0.0
 Identities = 464/476 (97%), Positives = 465/476 (97%)

Query: 3   MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 62
           MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP
Sbjct: 1   MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60

Query: 63  FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
           FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGV PRRWKLQVLDLQDVCENFWMVWSEAM
Sbjct: 61  FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120

Query: 123 AHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLLHL 182
           A GCFLNAKRNK PVQDCPRMRG+QPLTVFVELWLKNRTLDEYLT LLLWVKQRKDLLHL
Sbjct: 121 ARGCFLNAKRNKTPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180

Query: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 242
           CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS
Sbjct: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 240

Query: 243 HMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLT 302
           HMDVSRYVSPEQKKEIVTQFTTQFLKL CLQKL MNSVSFLEGHLDQLLSCLKTSLKVLT
Sbjct: 241 HMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVLT 300

Query: 303 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 362
           ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC
Sbjct: 301 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 360

Query: 363 GIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRESY 422
           GIIDSQVNAILPALSRCFELNTFSFCGNPI MATLENLLSHTIILKNLCVELYPAPRESY
Sbjct: 361 GIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRESY 420

Query: 423 GADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC 478
            ADGTLCWSRFAQIRAELM RVRDLRHPKRILFCTD CPDCGNRSFYDLEADQ CC
Sbjct: 421 DADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQCCC 476


>gi|226437621 PRAME family member 11 [Homo sapiens]
          Length = 436

 Score =  867 bits (2241), Expect = 0.0
 Identities = 422/436 (96%), Positives = 429/436 (98%)

Query: 43  MEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKL 102
           MEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKL
Sbjct: 1   MEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKL 60

Query: 103 QVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTL 162
           QVLDLQDVCENFWMVWSEAMAHGCFLNAKRNK PVQDCPRMR RQPLTVFVELWLKNRTL
Sbjct: 61  QVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTL 120

Query: 163 DEYLTYLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPI 222
           DEYLT LLLWVKQR+DLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKW+LPI
Sbjct: 121 DEYLTCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPI 180

Query: 223 LTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSF 282
           LTQFTPYLGH+RNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSF
Sbjct: 181 LTQFTPYLGHLRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSF 240

Query: 283 LEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVP 342
           LEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVP
Sbjct: 241 LEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVP 300

Query: 343 LQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLS 402
           LQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLS
Sbjct: 301 LQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLS 360

Query: 403 HTIILKNLCVELYPAPRESYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPD 462
           HTIILKNLC+ELYPAP+ESYGADGTLCWSRFAQIRAELM +VR LRHPKRILFCTD CPD
Sbjct: 361 HTIILKNLCLELYPAPQESYGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPD 420

Query: 463 CGNRSFYDLEADQYCC 478
            G+RSFYDLEADQYCC
Sbjct: 421 HGDRSFYDLEADQYCC 436


>gi|153792112 PRAME family member 20 [Homo sapiens]
          Length = 475

 Score =  788 bits (2035), Expect = 0.0
 Identities = 391/476 (82%), Positives = 418/476 (87%), Gaps = 1/476 (0%)

Query: 3   MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 62
           MSIRTPPRLLELAGRSLLRD+ALA+STLEELPTELFPPLFMEAFSRR CEALKLMVQAWP
Sbjct: 1   MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWP 60

Query: 63  FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
           F RLPL  L+K PC E FQAVLDGLDALLT  VR RRWKLQVLDLQDV ENFWMVWSEAM
Sbjct: 61  FLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAM 120

Query: 123 AHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLLHL 182
           A  C  NA  N+KPVQDCPRMRG+QPLTVF++L LKNRTLDEY T L LWVKQR+ L+HL
Sbjct: 121 ARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHL 180

Query: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 242
           CCKKLK+LGM F NIR+ILK VNLDCIQEVEVNC W LP+L +FTPYLG MRNL+KLVLS
Sbjct: 181 CCKKLKMLGMLFHNIRNILKTVNLDCIQEVEVNCNWTLPVLAEFTPYLGQMRNLRKLVLS 240

Query: 243 HMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLT 302
            +D SRY+SPEQKKE VTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQ+LSCLKTSL +L 
Sbjct: 241 DID-SRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNILA 299

Query: 303 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 362
           ITNCVLLESDLKHLS+ PSI QLKTLDLSG RL N+SLVPLQ+LLEKVAATLEYLDLDDC
Sbjct: 300 ITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDDC 359

Query: 363 GIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRESY 422
           GI+DSQVNAILPALSRCFEL TFSF GNPI  ATLENLL HTI L NLC+ELYPAPRESY
Sbjct: 360 GIVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRESY 419

Query: 423 GADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC 478
              G +C SRFAQ+ AELM RVR LR P+RILFCTDYCP CGNRS YDLE D+ CC
Sbjct: 420 DVRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGNRSLYDLEVDRCCC 475


>gi|153945800 PRAME family member 21 [Homo sapiens]
          Length = 475

 Score =  788 bits (2035), Expect = 0.0
 Identities = 391/476 (82%), Positives = 418/476 (87%), Gaps = 1/476 (0%)

Query: 3   MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 62
           MSIRTPPRLLELAGRSLLRD+ALA+STLEELPTELFPPLFMEAFSRR CEALKLMVQAWP
Sbjct: 1   MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWP 60

Query: 63  FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
           F RLPL  L+K PC E FQAVLDGLDALLT  VR RRWKLQVLDLQDV ENFWMVWSEAM
Sbjct: 61  FLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAM 120

Query: 123 AHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLLHL 182
           A  C  NA  N+KPVQDCPRMRG+QPLTVF++L LKNRTLDEY T L LWVKQR+ L+HL
Sbjct: 121 ARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHL 180

Query: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 242
           CCKKLK+LGM F NIR+ILK VNLDCIQEVEVNC W LP+L +FTPYLG MRNL+KLVLS
Sbjct: 181 CCKKLKMLGMLFHNIRNILKTVNLDCIQEVEVNCNWTLPVLAEFTPYLGQMRNLRKLVLS 240

Query: 243 HMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLT 302
            +D SRY+SPEQKKE VTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQ+LSCLKTSL +L 
Sbjct: 241 DID-SRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNILA 299

Query: 303 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 362
           ITNCVLLESDLKHLS+ PSI QLKTLDLSG RL N+SLVPLQ+LLEKVAATLEYLDLDDC
Sbjct: 300 ITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDDC 359

Query: 363 GIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRESY 422
           GI+DSQVNAILPALSRCFEL TFSF GNPI  ATLENLL HTI L NLC+ELYPAPRESY
Sbjct: 360 GIVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRESY 419

Query: 423 GADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC 478
              G +C SRFAQ+ AELM RVR LR P+RILFCTDYCP CGNRS YDLE D+ CC
Sbjct: 420 DVRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGNRSLYDLEVDRCCC 475


>gi|88942379 PREDICTED: PRAME family member [Homo sapiens]
          Length = 395

 Score =  764 bits (1973), Expect = 0.0
 Identities = 372/381 (97%), Positives = 374/381 (98%)

Query: 98  RRWKLQVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWL 157
           RRWKLQVLDLQDVCENFWMVWSEAMA GCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWL
Sbjct: 15  RRWKLQVLDLQDVCENFWMVWSEAMARGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWL 74

Query: 158 KNRTLDEYLTYLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCK 217
           KNRTLDE+LT LLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCK
Sbjct: 75  KNRTLDEHLTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCK 134

Query: 218 WVLPILTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYM 277
           WVLPILTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKL CLQKLYM
Sbjct: 135 WVLPILTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLHCLQKLYM 194

Query: 278 NSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTN 337
           NSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTN
Sbjct: 195 NSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTN 254

Query: 338 YSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATL 397
           YSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPI MATL
Sbjct: 255 YSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATL 314

Query: 398 ENLLSHTIILKNLCVELYPAPRESYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCT 457
           ENLLSHTIILKNLC+ELYPAPRESYGADGTLCWSRF QIRAELM RVRDLRHPKRILF T
Sbjct: 315 ENLLSHTIILKNLCLELYPAPRESYGADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGT 374

Query: 458 DYCPDCGNRSFYDLEADQYCC 478
           DYCPDCGNRSFYDLEADQYCC
Sbjct: 375 DYCPDCGNRSFYDLEADQYCC 395


>gi|239741047 PREDICTED: PRAME family member 25-like [Homo sapiens]
          Length = 474

 Score =  675 bits (1742), Expect = 0.0
 Identities = 345/477 (72%), Positives = 387/477 (81%), Gaps = 4/477 (0%)

Query: 3   MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 62
           MS++ P RLLELAG+SLL DQALA+S L+ELP ELFPPLF+EAF+ RRCE LK+MVQAWP
Sbjct: 1   MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 60

Query: 63  FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
           F  LPL  L+K P LE    V+DG+D LL Q VRPRR KLQVL+L+DV ENFW +WS A 
Sbjct: 61  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSGAR 120

Query: 123 AHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLLHL 182
              C   A   ++ V+DCPR   +QPL VF+++ LK + +DE L++   WV+ R+  +HL
Sbjct: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 180

Query: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKLVL 241
           CC K+    M   N R+IL+ V  D IQ +E+ N  W   I+ +F+PYL  MRNL+KL +
Sbjct: 181 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIV-EFSPYLSQMRNLRKLFI 239

Query: 242 SHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVL 301
           S  D  RY+     +E +  FTTQFLKL CLQKLYMNSVSFLEGHLDQLLSCLKTSLKVL
Sbjct: 240 S--DGCRYLLSSDSQEQIAPFTTQFLKLHCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVL 297

Query: 302 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 361
           TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD
Sbjct: 298 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 357

Query: 362 CGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRES 421
           CGIIDSQVNAILPALSRCFELNTFSFCGNPI MATLENLLSHTIILKNLC+ELYPAPRES
Sbjct: 358 CGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCLELYPAPRES 417

Query: 422 YGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC 478
           YGADGTLCWSRF QIRAELM RVRDLRHPKRILF TDYCPDCGNRSFYDLEADQYCC
Sbjct: 418 YGADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGTDYCPDCGNRSFYDLEADQYCC 474


>gi|239741053 PREDICTED: similar to Putative PRAME family member 24
           [Homo sapiens]
          Length = 474

 Score =  575 bits (1482), Expect = e-164
 Identities = 295/476 (61%), Positives = 357/476 (75%), Gaps = 2/476 (0%)

Query: 3   MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 62
           MSIR PPRLLELA + LLRDQALA+ST+EELP ELFP LFMEAFSRRRCE LK MVQAWP
Sbjct: 1   MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60

Query: 63  FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
           F RLPL  L+K P LE+ ++VL+G+D LLTQ VRPR+ KLQVLDL++V ENF  ++S A 
Sbjct: 61  FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120

Query: 123 AHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLLHL 182
           A   F  A   K+   +CP    +QP  VF++L LKNRTLDE LT+LL W KQRK LLH+
Sbjct: 121 AS--FPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178

Query: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 242
           CCK+L++ GMP  +I  +L MV LDCIQEVEV C W L  L +F PYLG MRNL+KLVL 
Sbjct: 179 CCKELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMRNLRKLVLF 238

Query: 243 HMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLT 302
           ++  S  + P+ K + + +FT+QFLKL   Q L M+SVSFLEGHLDQLL CL+ SL+++ 
Sbjct: 239 NIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLEMVV 298

Query: 303 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 362
           +T+C+L ESDLKHLS CPSI QLK LDL G+ LT++S  PL  LLE+V ATL+ LDL+DC
Sbjct: 299 MTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDLEDC 358

Query: 363 GIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRESY 422
           GI+DSQ++AILP LSRC +L+TFSFCGN I MA LENLL HT+ L  L +ELYPAP ESY
Sbjct: 359 GIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESY 418

Query: 423 GADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC 478
              G LCW RFA++ AELM  +RDLR PK I+FCT  CP CG R+ YDLE     C
Sbjct: 419 DTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHCLC 474


>gi|59676593 PRAME family member 7 [Homo sapiens]
          Length = 474

 Score =  574 bits (1479), Expect = e-164
 Identities = 295/476 (61%), Positives = 356/476 (74%), Gaps = 2/476 (0%)

Query: 3   MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 62
           MSIR PPRLLELA + LLRDQALA+ST+EELP ELFP LFMEAFSRRRCE LK MVQAWP
Sbjct: 1   MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60

Query: 63  FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
           F RLPL  L+K P LE+ ++VL+G+D LLTQ VRPR+ KLQVLDL++V ENF  ++S A 
Sbjct: 61  FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120

Query: 123 AHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLLHL 182
           A   F  A   K+   +CP    +QP  VF++L LKNRTLDE LT+LL W KQRK LLH+
Sbjct: 121 AS--FPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178

Query: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 242
           CCK+L++ GMP  +I  +L MV LDCIQEVEV C W L  L +F PYLG MRNL+KLVL 
Sbjct: 179 CCKELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMRNLRKLVLF 238

Query: 243 HMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLT 302
           ++  S  + P+ K + + +FT+QFLKL   Q L M+SVSFLEGHLDQLL CL+ SL+++ 
Sbjct: 239 NIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLEMVV 298

Query: 303 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 362
           +T+C+L ESDLKHLS CPSI QLK LDL G+ LT++S  PL  LLE+V ATL+ LDL+DC
Sbjct: 299 MTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDLEDC 358

Query: 363 GIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRESY 422
           GI+DSQ++AILP LSRC +L+TFSFCGN I MA LENLL HT+ L  L +ELYPAP ESY
Sbjct: 359 GIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESY 418

Query: 423 GADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC 478
              G LCW RFA++ AELM   RDLR PK I+FCT  CP CG R+ YDLE     C
Sbjct: 419 DTQGALCWGRFAELGAELMKTPRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHCLC 474


>gi|59676587 PRAME family member 8 [Homo sapiens]
          Length = 474

 Score =  573 bits (1478), Expect = e-164
 Identities = 294/476 (61%), Positives = 357/476 (75%), Gaps = 2/476 (0%)

Query: 3   MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 62
           MSIR PPRLLELA + LLRDQALA+ST+EELP ELFP LFMEAFSRRRCE LK MVQAWP
Sbjct: 1   MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60

Query: 63  FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
           F RLPL  L+K P LE+ ++VL+G+D LLTQ VRPR+ KLQVLDL++V ENF  ++S A 
Sbjct: 61  FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120

Query: 123 AHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLLHL 182
           A   F  A   K+   +CP    +QP  VF++L LKNRTLDE LT+LL W KQRK LLH+
Sbjct: 121 AS--FPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178

Query: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 242
           CC++L++ GMP  +I  +L MV LDCIQEVEV C W L  L +F PYLG MRNL+KLVL 
Sbjct: 179 CCQELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMRNLRKLVLF 238

Query: 243 HMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLT 302
           ++  S  + P+ K + + +FT+QFLKL   Q L M+SVSFLEGHLDQLL CL+ SL+++ 
Sbjct: 239 NIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLEMVV 298

Query: 303 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 362
           +T+C+L ESDLKHLS CPSI QLK LDL G+ LT++S  PL  LLE+V ATL+ LDL+DC
Sbjct: 299 MTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDLEDC 358

Query: 363 GIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRESY 422
           GI+DSQ++AILP LSRC +L+TFSFCGN I MA LENLL HT+ L  L +ELYPAP ESY
Sbjct: 359 GIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESY 418

Query: 423 GADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC 478
              G LCW RFA++ AELM  +RDLR PK I+FCT  CP CG R+ YDLE     C
Sbjct: 419 DTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHCLC 474


>gi|124249372 PRAME family member 12 [Homo sapiens]
          Length = 483

 Score =  570 bits (1470), Expect = e-163
 Identities = 295/470 (62%), Positives = 353/470 (75%), Gaps = 2/470 (0%)

Query: 3   MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 62
           MS++ PPRLLELA +SLLRD+ALA+ TLEELP ELFPPLFMEAF+RR CE L  MVQAWP
Sbjct: 1   MSLQAPPRLLELAEQSLLRDRALAIPTLEELPRELFPPLFMEAFTRRCCETLTTMVQAWP 60

Query: 63  FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
           F  LPL  L+K   LE F+AVL+GLDALL Q VRPRRWKLQVLDL++V ENFW +WS A 
Sbjct: 61  FTCLPLGSLMKSCNLEIFRAVLEGLDALLAQKVRPRRWKLQVLDLRNVDENFWGIWSGAS 120

Query: 123 AHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLLHL 182
           A      +KR  +   +CPR  G+QPL V ++L  KN  LDE LT+ L W KQRK LLH+
Sbjct: 121 ALSPEALSKR--RTAGNCPRPGGQQPLMVILDLCFKNGMLDECLTHFLEWGKQRKGLLHV 178

Query: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 242
           CCK+L+I G+    I  +L  V LDCIQEVEV C W L IL +F PYLG MRNL+KLVL 
Sbjct: 179 CCKELQIFGIAIHRIIEVLNTVELDCIQEVEVCCPWELSILIRFAPYLGQMRNLRKLVLF 238

Query: 243 HMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLT 302
           ++ VS  +  ++K++ V QFT+QFLKL   QKLYM+SVSFLEGHLDQLL CL+  L+ + 
Sbjct: 239 NIHVSACIPLDRKEQFVIQFTSQFLKLDYFQKLYMHSVSFLEGHLDQLLRCLQAPLETVV 298

Query: 303 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 362
           +T C+L ESDLKHLS CPSI QLK LDL GI LT++S  PL +LLE+  ATL+ LDL+DC
Sbjct: 299 MTECLLSESDLKHLSWCPSIRQLKELDLRGITLTHFSPEPLSVLLEQAEATLQTLDLEDC 358

Query: 363 GIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRESY 422
           GI+DSQ++AILPALSRC +L+TFSFCGN I MA LENLL HT+ L  L +ELYPAP ESY
Sbjct: 359 GIVDSQLSAILPALSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESY 418

Query: 423 GADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLE 472
            A G LCW RF+Q+ AELM  +RDLR PK I+F T  CP CG R+ YDLE
Sbjct: 419 DAQGALCWGRFSQLGAELMKTLRDLRQPKIIVFSTVPCPRCGIRASYDLE 468


>gi|46249373 preferentially expressed antigen in melanoma [Homo
           sapiens]
          Length = 509

 Score =  447 bits (1149), Expect = e-125
 Identities = 245/485 (50%), Positives = 322/485 (66%), Gaps = 13/485 (2%)

Query: 1   MKMSIRTPPR-LLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQ 59
           + MS+ T PR L+ELAG+SLL+D+ALA++ LE LP ELFPPLFM AF  R  + LK MVQ
Sbjct: 15  ISMSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQ 74

Query: 60  AWPFRRLPLRPLIKMPCL--EAFQAVLDGLDALLTQGVRPRRWKLQVLDLQ-DVCENFWM 116
           AWPF  LPL  L+K   L  E F+AVLDGLD LL Q VRPRRWKLQVLDL+ +  ++FW 
Sbjct: 75  AWPFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWT 134

Query: 117 VWSEAMAHGCFLNAKRNKKPVQDCPRMRGRQ--------PLTVFVELWLKNRTLDEYLTY 168
           VWS   A           +P+    ++ G          P+ V V+L+LK    DE  +Y
Sbjct: 135 VWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSY 194

Query: 169 LLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTP 228
           L+  VK++K++L LCCKKLKI  MP ++I+ ILKMV LD I+++EV C W LP L +F+P
Sbjct: 195 LIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSP 254

Query: 229 YLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLD 288
           YLG M NL++L+LSH+  S Y+SPE++++ + QFT+QFL L+CLQ LY++S+ FL G LD
Sbjct: 255 YLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLD 314

Query: 289 QLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLE 348
           QLL  +   L+ L+ITNC L E D+ HLSQ PS+SQL  L LSG+ LT+ S  PLQ LLE
Sbjct: 315 QLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLE 374

Query: 349 KVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILK 408
           + +ATL+ L  D+CGI D Q+ A+LP+LS C +L T SF GN I ++ L++LL H I L 
Sbjct: 375 RASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLS 434

Query: 409 NLCVELYPAPRESY-GADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRS 467
           NL   LYP P ESY    GTL   R A + A L   + +L  P  +    + CP CG+R+
Sbjct: 435 NLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGDRT 494

Query: 468 FYDLE 472
           FYD E
Sbjct: 495 FYDPE 499


>gi|46249371 preferentially expressed antigen in melanoma [Homo
           sapiens]
          Length = 509

 Score =  447 bits (1149), Expect = e-125
 Identities = 245/485 (50%), Positives = 322/485 (66%), Gaps = 13/485 (2%)

Query: 1   MKMSIRTPPR-LLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQ 59
           + MS+ T PR L+ELAG+SLL+D+ALA++ LE LP ELFPPLFM AF  R  + LK MVQ
Sbjct: 15  ISMSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQ 74

Query: 60  AWPFRRLPLRPLIKMPCL--EAFQAVLDGLDALLTQGVRPRRWKLQVLDLQ-DVCENFWM 116
           AWPF  LPL  L+K   L  E F+AVLDGLD LL Q VRPRRWKLQVLDL+ +  ++FW 
Sbjct: 75  AWPFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWT 134

Query: 117 VWSEAMAHGCFLNAKRNKKPVQDCPRMRGRQ--------PLTVFVELWLKNRTLDEYLTY 168
           VWS   A           +P+    ++ G          P+ V V+L+LK    DE  +Y
Sbjct: 135 VWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSY 194

Query: 169 LLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTP 228
           L+  VK++K++L LCCKKLKI  MP ++I+ ILKMV LD I+++EV C W LP L +F+P
Sbjct: 195 LIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSP 254

Query: 229 YLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLD 288
           YLG M NL++L+LSH+  S Y+SPE++++ + QFT+QFL L+CLQ LY++S+ FL G LD
Sbjct: 255 YLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLD 314

Query: 289 QLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLE 348
           QLL  +   L+ L+ITNC L E D+ HLSQ PS+SQL  L LSG+ LT+ S  PLQ LLE
Sbjct: 315 QLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLE 374

Query: 349 KVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILK 408
           + +ATL+ L  D+CGI D Q+ A+LP+LS C +L T SF GN I ++ L++LL H I L 
Sbjct: 375 RASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLS 434

Query: 409 NLCVELYPAPRESY-GADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRS 467
           NL   LYP P ESY    GTL   R A + A L   + +L  P  +    + CP CG+R+
Sbjct: 435 NLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGDRT 494

Query: 468 FYDLE 472
           FYD E
Sbjct: 495 FYDPE 499


>gi|46249369 preferentially expressed antigen in melanoma [Homo
           sapiens]
          Length = 509

 Score =  447 bits (1149), Expect = e-125
 Identities = 245/485 (50%), Positives = 322/485 (66%), Gaps = 13/485 (2%)

Query: 1   MKMSIRTPPR-LLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQ 59
           + MS+ T PR L+ELAG+SLL+D+ALA++ LE LP ELFPPLFM AF  R  + LK MVQ
Sbjct: 15  ISMSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQ 74

Query: 60  AWPFRRLPLRPLIKMPCL--EAFQAVLDGLDALLTQGVRPRRWKLQVLDLQ-DVCENFWM 116
           AWPF  LPL  L+K   L  E F+AVLDGLD LL Q VRPRRWKLQVLDL+ +  ++FW 
Sbjct: 75  AWPFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWT 134

Query: 117 VWSEAMAHGCFLNAKRNKKPVQDCPRMRGRQ--------PLTVFVELWLKNRTLDEYLTY 168
           VWS   A           +P+    ++ G          P+ V V+L+LK    DE  +Y
Sbjct: 135 VWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSY 194

Query: 169 LLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTP 228
           L+  VK++K++L LCCKKLKI  MP ++I+ ILKMV LD I+++EV C W LP L +F+P
Sbjct: 195 LIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSP 254

Query: 229 YLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLD 288
           YLG M NL++L+LSH+  S Y+SPE++++ + QFT+QFL L+CLQ LY++S+ FL G LD
Sbjct: 255 YLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLD 314

Query: 289 QLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLE 348
           QLL  +   L+ L+ITNC L E D+ HLSQ PS+SQL  L LSG+ LT+ S  PLQ LLE
Sbjct: 315 QLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLE 374

Query: 349 KVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILK 408
           + +ATL+ L  D+CGI D Q+ A+LP+LS C +L T SF GN I ++ L++LL H I L 
Sbjct: 375 RASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLS 434

Query: 409 NLCVELYPAPRESY-GADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRS 467
           NL   LYP P ESY    GTL   R A + A L   + +L  P  +    + CP CG+R+
Sbjct: 435 NLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGDRT 494

Query: 468 FYDLE 472
           FYD E
Sbjct: 495 FYDPE 499


>gi|46249367 preferentially expressed antigen in melanoma [Homo
           sapiens]
          Length = 509

 Score =  447 bits (1149), Expect = e-125
 Identities = 245/485 (50%), Positives = 322/485 (66%), Gaps = 13/485 (2%)

Query: 1   MKMSIRTPPR-LLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQ 59
           + MS+ T PR L+ELAG+SLL+D+ALA++ LE LP ELFPPLFM AF  R  + LK MVQ
Sbjct: 15  ISMSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQ 74

Query: 60  AWPFRRLPLRPLIKMPCL--EAFQAVLDGLDALLTQGVRPRRWKLQVLDLQ-DVCENFWM 116
           AWPF  LPL  L+K   L  E F+AVLDGLD LL Q VRPRRWKLQVLDL+ +  ++FW 
Sbjct: 75  AWPFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWT 134

Query: 117 VWSEAMAHGCFLNAKRNKKPVQDCPRMRGRQ--------PLTVFVELWLKNRTLDEYLTY 168
           VWS   A           +P+    ++ G          P+ V V+L+LK    DE  +Y
Sbjct: 135 VWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSY 194

Query: 169 LLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTP 228
           L+  VK++K++L LCCKKLKI  MP ++I+ ILKMV LD I+++EV C W LP L +F+P
Sbjct: 195 LIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSP 254

Query: 229 YLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLD 288
           YLG M NL++L+LSH+  S Y+SPE++++ + QFT+QFL L+CLQ LY++S+ FL G LD
Sbjct: 255 YLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLD 314

Query: 289 QLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLE 348
           QLL  +   L+ L+ITNC L E D+ HLSQ PS+SQL  L LSG+ LT+ S  PLQ LLE
Sbjct: 315 QLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLE 374

Query: 349 KVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILK 408
           + +ATL+ L  D+CGI D Q+ A+LP+LS C +L T SF GN I ++ L++LL H I L 
Sbjct: 375 RASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLS 434

Query: 409 NLCVELYPAPRESY-GADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRS 467
           NL   LYP P ESY    GTL   R A + A L   + +L  P  +    + CP CG+R+
Sbjct: 435 NLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGDRT 494

Query: 468 FYDLE 472
           FYD E
Sbjct: 495 FYDPE 499


>gi|5174641 preferentially expressed antigen in melanoma [Homo
           sapiens]
          Length = 509

 Score =  447 bits (1149), Expect = e-125
 Identities = 245/485 (50%), Positives = 322/485 (66%), Gaps = 13/485 (2%)

Query: 1   MKMSIRTPPR-LLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQ 59
           + MS+ T PR L+ELAG+SLL+D+ALA++ LE LP ELFPPLFM AF  R  + LK MVQ
Sbjct: 15  ISMSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQ 74

Query: 60  AWPFRRLPLRPLIKMPCL--EAFQAVLDGLDALLTQGVRPRRWKLQVLDLQ-DVCENFWM 116
           AWPF  LPL  L+K   L  E F+AVLDGLD LL Q VRPRRWKLQVLDL+ +  ++FW 
Sbjct: 75  AWPFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWT 134

Query: 117 VWSEAMAHGCFLNAKRNKKPVQDCPRMRGRQ--------PLTVFVELWLKNRTLDEYLTY 168
           VWS   A           +P+    ++ G          P+ V V+L+LK    DE  +Y
Sbjct: 135 VWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSY 194

Query: 169 LLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTP 228
           L+  VK++K++L LCCKKLKI  MP ++I+ ILKMV LD I+++EV C W LP L +F+P
Sbjct: 195 LIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSP 254

Query: 229 YLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLD 288
           YLG M NL++L+LSH+  S Y+SPE++++ + QFT+QFL L+CLQ LY++S+ FL G LD
Sbjct: 255 YLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLD 314

Query: 289 QLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLE 348
           QLL  +   L+ L+ITNC L E D+ HLSQ PS+SQL  L LSG+ LT+ S  PLQ LLE
Sbjct: 315 QLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLE 374

Query: 349 KVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILK 408
           + +ATL+ L  D+CGI D Q+ A+LP+LS C +L T SF GN I ++ L++LL H I L 
Sbjct: 375 RASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLS 434

Query: 409 NLCVELYPAPRESY-GADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRS 467
           NL   LYP P ESY    GTL   R A + A L   + +L  P  +    + CP CG+R+
Sbjct: 435 NLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGDRT 494

Query: 468 FYDLE 472
           FYD E
Sbjct: 495 FYDPE 499


>gi|154800493 PRAME family member 22 [Homo sapiens]
          Length = 481

 Score =  426 bits (1095), Expect = e-119
 Identities = 238/474 (50%), Positives = 311/474 (65%), Gaps = 5/474 (1%)

Query: 1   MKMSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQA 60
           M+MS++ P RLLELAG+SLL DQALA+S L+ELP ELFPPLF+EAF+ RRCE LK+MVQA
Sbjct: 1   MRMSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQA 60

Query: 61  WPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSE 120
           WPF  LPL  L+K P LE    V+DG+D LL Q VRPRRWKLQVL+L+DV ENFW +WS 
Sbjct: 61  WPFPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSG 120

Query: 121 AMAHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLL 180
           A    C   A   ++ V+DCPR   +QPL VF+++ LK + +DE L++   WV+ R+  +
Sbjct: 121 ARPLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSV 180

Query: 181 HLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKL 239
           HLCC K+    M   N R+IL+ V  D IQ +E+ N  W   ++ +F+ YL  MRNL+KL
Sbjct: 181 HLCCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPC-MIVEFSRYLSQMRNLRKL 239

Query: 240 VLSHMDVSRY-VSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSL 298
            +S  D  RY +S + ++++V +F++  L+L  LQ LY+  V F  GHLDQL+ CL++ L
Sbjct: 240 FIS--DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPL 297

Query: 299 KVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLD 358
           + L +T   L + DLK L + PS+SQLK L+LS   L    L PL+ LLEKVAATL+ L 
Sbjct: 298 ETLALTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLF 357

Query: 359 LDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAP 418
           L DCGI DS++  ILPALS C  L TF F GN   M  L++LL HT  L NL +E YPAP
Sbjct: 358 LVDCGIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAP 417

Query: 419 RESYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLE 472
           RES    G +       ++AELM  +R++R PKRI F    CP CG      LE
Sbjct: 418 RESLDDRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLE 471


>gi|194306638 PRAME family member 3 [Homo sapiens]
          Length = 481

 Score =  420 bits (1079), Expect = e-117
 Identities = 237/474 (50%), Positives = 309/474 (65%), Gaps = 5/474 (1%)

Query: 1   MKMSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQA 60
           M+MS++ P RLLELAG+SLL DQALA+S L+ELP ELFPPLF+EAF+ RRCE LK+MVQA
Sbjct: 1   MRMSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQA 60

Query: 61  WPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSE 120
           WPF  LPL  L+K P LE    V+DG+D LL Q VRPRR KLQVL+L+DV ENFW +WS 
Sbjct: 61  WPFPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSG 120

Query: 121 AMAHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLL 180
           A    C   A   ++ V+DCPR   +QPL VF+++ LK + +DE L++   WV+ R+  +
Sbjct: 121 ARPLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSV 180

Query: 181 HLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKL 239
           HLCC K+    M   N R+IL+ V  D IQ +E+ N  W   ++ +F  YL  MRNL+KL
Sbjct: 181 HLCCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPC-MIVEFIRYLSQMRNLRKL 239

Query: 240 VLSHMDVSRY-VSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSL 298
            +S  D  RY +S + ++++V +F++  L+L  LQ LY+  V F  GHLDQL+ CL++ L
Sbjct: 240 FIS--DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPL 297

Query: 299 KVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLD 358
           + L +T   L + DLK L + PS+SQLK L+LS   L    L PL+ LLEKVAATL+ L 
Sbjct: 298 ETLALTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLF 357

Query: 359 LDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAP 418
           L DCGI DS++  ILPALS C  L TF F GN   M  L++LL HT  L NL +E YPAP
Sbjct: 358 LVDCGIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAP 417

Query: 419 RESYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLE 472
           RES    G +       ++AELM  +R++R PKRI F    CP CG      LE
Sbjct: 418 RESLDDRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLE 471


>gi|153791443 PRAME family member 18 [Homo sapiens]
          Length = 479

 Score =  418 bits (1074), Expect = e-117
 Identities = 237/472 (50%), Positives = 307/472 (65%), Gaps = 5/472 (1%)

Query: 3   MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 62
           MS + P RLLELAG+SLLRDQALA+S L+ELP ELFP LF+EAF+ RRCE LK+MVQAWP
Sbjct: 1   MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60

Query: 63  FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
           F  LPL  L+K P LE    V+DG+D LL Q VRPRRWKLQVL+++DV ENFW +WS A 
Sbjct: 61  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120

Query: 123 AHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLLHL 182
              C   A   ++ V+DCPR   +QPL VF+++ LK +++DE L++   WV+ R+  +HL
Sbjct: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180

Query: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKLVL 241
           CC K+    M   N R+IL+ V  D IQ +E+ N  W   ++ + + YL  M+NL+KL +
Sbjct: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPC-MVAEVSRYLSQMKNLRKLFI 239

Query: 242 SHMDVSRYV-SPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKV 300
           S  D   Y+ S E + ++V +F++ FL+L  LQ LYM  + F EG+LDQL+ CLK+ L+ 
Sbjct: 240 S--DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLET 297

Query: 301 LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD 360
           L +T   L E DLK L   PS+SQLK L+LS   L    L PL+ LLEKVAATL+ L L 
Sbjct: 298 LALTYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLV 357

Query: 361 DCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRE 420
           DCGI DS++  ILPALSRC  L TF F GN   M  L++LL HT  L NL +E YPAPRE
Sbjct: 358 DCGIGDSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRE 417

Query: 421 SYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLE 472
           S    G +       ++AELM  +R++R P RI F    CP CG      LE
Sbjct: 418 SLDNRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLE 469


>gi|113865933 PRAME family member 16 [Homo sapiens]
          Length = 474

 Score =  415 bits (1066), Expect = e-116
 Identities = 236/464 (50%), Positives = 293/464 (63%), Gaps = 3/464 (0%)

Query: 3   MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 62
           MS+++P RLLELAG+SLLR+Q L +  L+ELP E+FP +FMEA S R  EALKLMVQAWP
Sbjct: 1   MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60

Query: 63  FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
           F RLPL  L+K P LE  QAVL GLD LL Q +RPRRWKLQVLDL+DV  NFW +WS A 
Sbjct: 61  FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120

Query: 123 AHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLLHL 182
           A  C   A R ++ V+D PR    QPL VF++L  K  TLDE L+YL  W+  R+ L+HL
Sbjct: 121 ALSCSPEAMRKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180

Query: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 242
           CC K++   MP  + R++LK V  D IQE+E+  K  L    +F PYL  M NL+KL L+
Sbjct: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240

Query: 243 H-MDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVL 301
              D   YVS +Q  + V      FL L   Q LY+  +S ++ HL+ LL CLK  L   
Sbjct: 241 FGYDDELYVSGQQ--QFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTF 298

Query: 302 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 361
              +  L + D++ LSQ PS+SQLK L L  I +   +L PL  LLEKVAATLE L L D
Sbjct: 299 IFCHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKD 358

Query: 362 CGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRES 421
           C I DSQ+  +LPALSRC +L TF F GN      L++LL HT  L  L +ELYPAP E 
Sbjct: 359 CQIQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLEC 418

Query: 422 YGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGN 465
               G + W   A IRAELM  +R++R PKRI F    CP CG+
Sbjct: 419 LDNRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGS 462


>gi|194306635 PRAME family member 19 [Homo sapiens]
          Length = 479

 Score =  414 bits (1065), Expect = e-116
 Identities = 236/472 (50%), Positives = 306/472 (64%), Gaps = 5/472 (1%)

Query: 3   MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 62
           MS + P RLLELAG+SLLRDQALA+S L+ELP ELFP LF+EAF+ RRCE LK+MVQAWP
Sbjct: 1   MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60

Query: 63  FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
           F  LPL  L+K P LE    V+DG+D LL Q VRPRRWKLQVL+++DV ENFW +WS A 
Sbjct: 61  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120

Query: 123 AHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLLHL 182
              C   A   ++ V+DCPR   +QPL VF+++ LK +++DE L++   WV+ R+  +HL
Sbjct: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180

Query: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKLVL 241
           CC K+    M   N R+IL+ V  D IQ +E+ N  W   ++ + + YL  M+NL+KL +
Sbjct: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPC-MVAEVSRYLSQMKNLRKLFI 239

Query: 242 SHMDVSRYV-SPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKV 300
           S  D   Y+ S E + ++V +F++ FL+L  LQ LYM  + F EG+LDQL+ CLK+ L+ 
Sbjct: 240 S--DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLET 297

Query: 301 LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD 360
           L +T   L E DLK L   PS+SQLK L+LS   L    L PL+ LLEKVAATL+ L L 
Sbjct: 298 LALTYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLV 357

Query: 361 DCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRE 420
           DCGI  S++  ILPALSRC  L TF F GN   M  L++LL HT  L NL +E YPAPRE
Sbjct: 358 DCGIGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRE 417

Query: 421 SYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLE 472
           S    G +       ++AELM  +R++R P RI F    CP CG      LE
Sbjct: 418 SLDNRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLE 469


>gi|157426839 PRAME family member 17 [Homo sapiens]
          Length = 474

 Score =  412 bits (1060), Expect = e-115
 Identities = 235/464 (50%), Positives = 292/464 (62%), Gaps = 3/464 (0%)

Query: 3   MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 62
           MS+++P RLLELAG+SLLR+Q L +  L+ELP E+FP +FMEA S R  EALKLMVQAWP
Sbjct: 1   MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60

Query: 63  FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
           F RLPL  L+K P LE  QAVL GLD LL Q +RPRRWKLQVLDL+DV  NFW +WS A 
Sbjct: 61  FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120

Query: 123 AHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLLHL 182
           A  C   A   ++ V+D PR    QPL VF++L  K  TLDE L+YL  W+  R+ L+HL
Sbjct: 121 ALSCSPEAMSKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180

Query: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 242
           CC K++   MP  + R++LK V  D IQE+E+  K  L    +F PYL  M NL+KL L+
Sbjct: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240

Query: 243 H-MDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVL 301
              D   YVS +Q  + V      FL L   Q LY+  +S ++ HL+ LL CLK  L   
Sbjct: 241 FGYDDELYVSGQQ--QFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTF 298

Query: 302 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 361
              +  L + D++ LSQ PS+SQLK L L  I +   +L PL  LLEKVAATLE L L D
Sbjct: 299 IFCHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKD 358

Query: 362 CGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRES 421
           C I DSQ+  +LPALSRC +L TF F GN      L++LL HT  L  L +ELYPAP E 
Sbjct: 359 CQIQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLEC 418

Query: 422 YGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGN 465
               G + W   A IRAELM  +R++R PKRI F    CP CG+
Sbjct: 419 LDNRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGS 462


>gi|66954681 PRAME family member 13 [Homo sapiens]
          Length = 474

 Score =  410 bits (1055), Expect = e-114
 Identities = 233/477 (48%), Positives = 304/477 (63%), Gaps = 4/477 (0%)

Query: 3   MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 62
           MSI+ PPRLLELAG+SLLRDQAL++S +EELP  L+ PLFMEAF RR  + L +MVQAWP
Sbjct: 1   MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60

Query: 63  FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
           F  LPL  L+K   LE  +A+L+GL  LLTQ  RPRRWKLQVLDL+DV ENFW  W  A 
Sbjct: 61  FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120

Query: 123 AHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLLHL 182
           A  CF      ++  +DCPRM   QPL VF+++ LK    DE L YL  WV QR+ L+HL
Sbjct: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180

Query: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKLVL 241
           CC KL     P +++R  LK++ L+ IQ++E+ N  W   ++ +   YL  M+NL+KLV 
Sbjct: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWP-RLIRKLRCYLKEMKNLRKLVF 239

Query: 242 SHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVL 301
           S    S     E +  +VT+F++ FL+L  LQ L +  ++F  GHL+QL+ CL+  L+ L
Sbjct: 240 SRCHHS-MSDNELEGRLVTKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENL 298

Query: 302 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 361
            +T   LLE D+K LSQ PS+  LK L+LS + L   SL PL  LLEK+AA+LE L L+ 
Sbjct: 299 ELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEG 358

Query: 362 CGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRES 421
           C I  SQ++AILP LS C +L TF F  N + M  L++LL HT  L  L +E YPAP ES
Sbjct: 359 CQIHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLRHTSGLSKLSLETYPAPEES 418

Query: 422 YGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC 478
             +   + W  FA +RAELM  +R++R PKRI      CP CG+    +LE    CC
Sbjct: 419 LNSLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELEL-HLCC 474


>gi|12738831 PRAME family member 1 [Homo sapiens]
          Length = 474

 Score =  409 bits (1052), Expect = e-114
 Identities = 234/478 (48%), Positives = 305/478 (63%), Gaps = 6/478 (1%)

Query: 3   MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 62
           MSI+ PPRLLELAG+SLLRDQAL++S +EELP  L+ PLFMEAFSRR  + L +MVQAWP
Sbjct: 1   MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFSRRHFQTLTVMVQAWP 60

Query: 63  FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
           F  LPL  L+K   LE  +A+L+GL  LLTQ  RPRRWKLQVLDL+DV ENFW  W  A 
Sbjct: 61  FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120

Query: 123 AHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLLHL 182
           A  CF      ++  +DCPRM   QPL VF+++ LK    DE L YL  WV QR+ L+HL
Sbjct: 121 ALSCFPETTSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180

Query: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKLVL 241
           CC KL     P + +R  LK++ L+ IQE+E+ N  W   ++ +   YL  M+NL+KLV 
Sbjct: 181 CCSKLVNYLTPIKYLRKSLKIIYLNSIQELEIRNMSWP-RLIRKLRCYLKEMKNLRKLVF 239

Query: 242 SHMDVSRYVSP-EQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKV 300
           S      Y S  E +  +V +F++ FL+L  LQ L +  ++F  GHL+QL+ CL+  L+ 
Sbjct: 240 SR--CHHYTSDNELQGRLVAKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLEN 297

Query: 301 LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD 360
           L +T   LLE D+K LSQ PS+  LK L+LS + L   SL PL  LLEK+AA+L+ L L+
Sbjct: 298 LELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLKTLILE 357

Query: 361 DCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRE 420
            C I  SQ++AILPALSRC +L TF F  N + +  L++LL HT  L  L +E YPAP E
Sbjct: 358 GCQIHYSQLSAILPALSRCSQLTTFYFGRNCMSIDALKDLLRHTSGLSKLSLETYPAPEE 417

Query: 421 SYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC 478
           S  +   + W  F  +RAELM  +R++R PKRI      CP CG+    +LE    CC
Sbjct: 418 SLNSLVRVNWEIFTPLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELEL-HLCC 474


>gi|194018546 PRAME family member 10 [Homo sapiens]
          Length = 474

 Score =  408 bits (1049), Expect = e-114
 Identities = 231/464 (49%), Positives = 295/464 (63%), Gaps = 3/464 (0%)

Query: 3   MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 62
           MS++ P RLLELAG+SLLR+Q L + TL+ELP E+FP +FMEAFS RR EALKLMVQAWP
Sbjct: 1   MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60

Query: 63  FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
           F  LPL  L+K   LE  QAVL GLD L+ Q VRPRRWKLQVLDL+DV ENFW +WS A 
Sbjct: 61  FLSLPLGSLMKTLHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120

Query: 123 AHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLLHL 182
              C   A   ++ V+DCPRM   QPL VF++L LK  TLDE L+YL  W+  R+ L+HL
Sbjct: 121 VLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180

Query: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 242
           CC K++   MP  + R++L+ +  D IQE+EV  K  L    +F PYL  M NL++L L+
Sbjct: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLA 240

Query: 243 H-MDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVL 301
              +   YVS +     +    + FL L   Q LY+  +S ++ HL+ LL  LK  L   
Sbjct: 241 FGYERELYVSVQW--PCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAF 298

Query: 302 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 361
             ++  L + D++ LSQ PS+SQLK L L  I +    L PL +LLEKVAATL+ L L D
Sbjct: 299 IFSDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKD 358

Query: 362 CGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRES 421
           C I D Q+  +LPALS C +L TF+F GN   M  L++LL HT  L  L +ELYPAP ES
Sbjct: 359 CRIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTGGLSKLGLELYPAPLES 418

Query: 422 YGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGN 465
               G + W     IRAELM  +R++R PKRI F    CP+CG+
Sbjct: 419 LDYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPNCGS 462


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.327    0.140    0.442 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,981,691
Number of Sequences: 37866
Number of extensions: 771108
Number of successful extensions: 2216
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 49
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 2089
Number of HSP's gapped (non-prelim): 78
length of query: 478
length of database: 18,247,518
effective HSP length: 106
effective length of query: 372
effective length of database: 14,233,722
effective search space: 5294944584
effective search space used: 5294944584
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.